LOCUS       DBBGRF010000001       134475 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000001 DBBGRF010000000
VERSION     DBBGRF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 134475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 134475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..134475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.001"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(531..2027)
                     /gene="lysS"
                     /locus_tag="ACIZD4_000001"
     CDS             complement(531..2027)
                     /gene="lysS"
                     /locus_tag="ACIZD4_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGC5988973.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="ACIZD4_000002"
     CDS             complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="ACIZD4_000002"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGC5988974.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="ACIZD4_000003"
     CDS             complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="ACIZD4_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGC5988975.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="ACIZD4_000004"
     CDS             complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="ACIZD4_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGC5988976.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="ACIZD4_000005"
     CDS             complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="ACIZD4_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGC5988977.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="ACIZD4_000006"
     CDS             complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="ACIZD4_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGC5988978.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8558..9028)
                     /locus_tag="ACIZD4_000007"
     CDS             complement(8558..9028)
                     /locus_tag="ACIZD4_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HGC5988979.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9074..9499)
                     /locus_tag="ACIZD4_000008"
     CDS             complement(9074..9499)
                     /locus_tag="ACIZD4_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGC5988980.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9566..9835)
                     /locus_tag="ACIZD4_000009"
     CDS             complement(9566..9835)
                     /locus_tag="ACIZD4_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGC5988981.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9846..11441)
                     /locus_tag="ACIZD4_000010"
     CDS             complement(9846..11441)
                     /locus_tag="ACIZD4_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC5988982.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="ACIZD4_000011"
     CDS             complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="ACIZD4_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGC5988983.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14994..15554)
                     /gene="pth"
                     /locus_tag="ACIZD4_000012"
     CDS             complement(14994..15554)
                     /gene="pth"
                     /locus_tag="ACIZD4_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGC5988984.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15907..16881
                     /locus_tag="ACIZD4_000013"
     CDS             15907..16881
                     /locus_tag="ACIZD4_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGC5988985.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17051..18451
                     /locus_tag="ACIZD4_000014"
     CDS             17051..18451
                     /locus_tag="ACIZD4_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HGC5988986.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18529..19251)
                     /locus_tag="ACIZD4_000015"
     CDS             complement(18529..19251)
                     /locus_tag="ACIZD4_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5988987.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19330..19836)
                     /locus_tag="ACIZD4_000016"
     CDS             complement(19330..19836)
                     /locus_tag="ACIZD4_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC5988988.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19959..21758
                     /locus_tag="ACIZD4_000017"
     CDS             19959..21758
                     /locus_tag="ACIZD4_000017"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HGC5988989.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21826..23400)
                     /locus_tag="ACIZD4_000018"
     CDS             complement(21826..23400)
                     /locus_tag="ACIZD4_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HGC5988990.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23655..24164)
                     /gene="mreD"
                     /locus_tag="ACIZD4_000019"
     CDS             complement(23655..24164)
                     /gene="mreD"
                     /locus_tag="ACIZD4_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGC5988991.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24168..25022)
                     /gene="mreC"
                     /locus_tag="ACIZD4_000020"
     CDS             complement(24168..25022)
                     /gene="mreC"
                     /locus_tag="ACIZD4_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGC5988992.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25177..25815)
                     /locus_tag="ACIZD4_000021"
     CDS             complement(25177..25815)
                     /locus_tag="ACIZD4_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGC5988993.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25816..26466)
                     /gene="rpe"
                     /locus_tag="ACIZD4_000022"
     CDS             complement(25816..26466)
                     /gene="rpe"
                     /locus_tag="ACIZD4_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGC5988994.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26479..27378)
                     /gene="rsgA"
                     /locus_tag="ACIZD4_000023"
     CDS             complement(26479..27378)
                     /gene="rsgA"
                     /locus_tag="ACIZD4_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGC5988995.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27543..29612)
                     /gene="pknB"
                     /locus_tag="ACIZD4_000024"
     CDS             complement(27543..29612)
                     /gene="pknB"
                     /locus_tag="ACIZD4_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HGC5988996.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29609..30349)
                     /locus_tag="ACIZD4_000025"
     CDS             complement(29609..30349)
                     /locus_tag="ACIZD4_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGC5988997.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30362..31720)
                     /gene="rsmB"
                     /locus_tag="ACIZD4_000026"
     CDS             complement(30362..31720)
                     /gene="rsmB"
                     /locus_tag="ACIZD4_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGC5988998.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31720..32658)
                     /gene="fmt"
                     /locus_tag="ACIZD4_000027"
     CDS             complement(31720..32658)
                     /gene="fmt"
                     /locus_tag="ACIZD4_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGC5988999.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32651..33142)
                     /gene="def"
                     /locus_tag="ACIZD4_000028"
     CDS             complement(32651..33142)
                     /gene="def"
                     /locus_tag="ACIZD4_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGC5989000.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33157..35565)
                     /gene="priA"
                     /locus_tag="ACIZD4_000029"
     CDS             complement(33157..35565)
                     /gene="priA"
                     /locus_tag="ACIZD4_000029"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGC5989001.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35818..36123)
                     /gene="rpoZ"
                     /locus_tag="ACIZD4_000030"
     CDS             complement(35818..36123)
                     /gene="rpoZ"
                     /locus_tag="ACIZD4_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGC5989002.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36128..36742)
                     /gene="gmk"
                     /locus_tag="ACIZD4_000031"
     CDS             complement(36128..36742)
                     /gene="gmk"
                     /locus_tag="ACIZD4_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGC5989003.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37229..37513)
                     /locus_tag="ACIZD4_000032"
     CDS             complement(37229..37513)
                     /locus_tag="ACIZD4_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989004.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37531..38421)
                     /locus_tag="ACIZD4_000033"
     CDS             complement(37531..38421)
                     /locus_tag="ACIZD4_000033"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HGC5989005.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38441..38659)
                     /locus_tag="ACIZD4_000034"
     CDS             complement(38441..38659)
                     /locus_tag="ACIZD4_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGC5989006.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38629..40329)
                     /locus_tag="ACIZD4_000035"
     CDS             complement(38629..40329)
                     /locus_tag="ACIZD4_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HGC5989007.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40596..41369
                     /locus_tag="ACIZD4_000036"
     CDS             40596..41369
                     /locus_tag="ACIZD4_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989008.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41450..42019)
                     /gene="thiT"
                     /locus_tag="ACIZD4_000037"
     CDS             complement(41450..42019)
                     /gene="thiT"
                     /locus_tag="ACIZD4_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HGC5989009.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42085..42187)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42193..43164)
                     /locus_tag="ACIZD4_000038"
     CDS             complement(42193..43164)
                     /locus_tag="ACIZD4_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGC5989010.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43258..44631)
                     /gene="glmU"
                     /locus_tag="ACIZD4_000039"
     CDS             complement(43258..44631)
                     /gene="glmU"
                     /locus_tag="ACIZD4_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGC5989011.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45134..45952)
                     /gene="purR"
                     /locus_tag="ACIZD4_000040"
     CDS             complement(45134..45952)
                     /gene="purR"
                     /locus_tag="ACIZD4_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGC5989012.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46119..46943)
                     /locus_tag="ACIZD4_000041"
     CDS             complement(46119..46943)
                     /locus_tag="ACIZD4_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGC5989013.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46916..47596)
                     /locus_tag="ACIZD4_000042"
     CDS             complement(46916..47596)
                     /locus_tag="ACIZD4_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGC5989014.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47619..48557)
                     /locus_tag="ACIZD4_000043"
     CDS             complement(47619..48557)
                     /locus_tag="ACIZD4_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HGC5989015.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48802..49653)
                     /gene="ispE"
                     /locus_tag="ACIZD4_000044"
     CDS             complement(48802..49653)
                     /gene="ispE"
                     /locus_tag="ACIZD4_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HGC5989016.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49807..52380)
                     /gene="mprF"
                     /locus_tag="ACIZD4_000045"
     CDS             complement(49807..52380)
                     /gene="mprF"
                     /locus_tag="ACIZD4_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HGC5989017.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52521..53327
                     /gene="proC"
                     /locus_tag="ACIZD4_000046"
     CDS             52521..53327
                     /gene="proC"
                     /locus_tag="ACIZD4_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGC5989018.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53406..54962)
                     /gene="rny"
                     /locus_tag="ACIZD4_000047"
     CDS             complement(53406..54962)
                     /gene="rny"
                     /locus_tag="ACIZD4_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGC5989019.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55373..56422)
                     /gene="recA"
                     /locus_tag="ACIZD4_000048"
     CDS             complement(55373..56422)
                     /gene="recA"
                     /locus_tag="ACIZD4_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGC5989020.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56531..57772)
                     /locus_tag="ACIZD4_000049"
     CDS             complement(56531..57772)
                     /locus_tag="ACIZD4_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGC5989021.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(58012..58590)
                     /gene="pgsA"
                     /locus_tag="ACIZD4_000050"
     CDS             complement(58012..58590)
                     /gene="pgsA"
                     /locus_tag="ACIZD4_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGC5989022.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58799..59722)
                     /locus_tag="ACIZD4_000051"
     CDS             complement(58799..59722)
                     /locus_tag="ACIZD4_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HGC5989023.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60461..61747)
                     /locus_tag="ACIZD4_000052"
     CDS             complement(60461..61747)
                     /locus_tag="ACIZD4_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGC5989024.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61740..63008)
                     /locus_tag="ACIZD4_000053"
     CDS             complement(61740..63008)
                     /locus_tag="ACIZD4_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGC5989025.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63260..63721
                     /gene="mscL"
                     /locus_tag="ACIZD4_000054"
     CDS             63260..63721
                     /gene="mscL"
                     /locus_tag="ACIZD4_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGC5989026.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63780..64226)
                     /locus_tag="ACIZD4_000055"
     CDS             complement(63780..64226)
                     /locus_tag="ACIZD4_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5989027.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64319..64564)
                     /locus_tag="ACIZD4_000056"
     CDS             complement(64319..64564)
                     /locus_tag="ACIZD4_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGC5989028.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64679..65257)
                     /locus_tag="ACIZD4_000057"
     CDS             complement(64679..65257)
                     /locus_tag="ACIZD4_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC5989029.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65334..65864)
                     /locus_tag="ACIZD4_000058"
     CDS             complement(65334..65864)
                     /locus_tag="ACIZD4_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HGC5989030.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65868..66728)
                     /gene="rlmB"
                     /locus_tag="ACIZD4_000059"
     CDS             complement(65868..66728)
                     /gene="rlmB"
                     /locus_tag="ACIZD4_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGC5989031.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66721..67116)
                     /locus_tag="ACIZD4_000060"
     CDS             complement(66721..67116)
                     /locus_tag="ACIZD4_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGC5989032.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSTKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67113..68525)
                     /gene="cysS"
                     /locus_tag="ACIZD4_000061"
     CDS             complement(67113..68525)
                     /gene="cysS"
                     /locus_tag="ACIZD4_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGC5989033.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68522..69058)
                     /gene="epsC"
                     /locus_tag="ACIZD4_000062"
     CDS             complement(68522..69058)
                     /gene="epsC"
                     /locus_tag="ACIZD4_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HGC5989034.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69144..69383)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69380..70840)
                     /gene="gltX"
                     /locus_tag="ACIZD4_000063"
     CDS             complement(69380..70840)
                     /gene="gltX"
                     /locus_tag="ACIZD4_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGC5989035.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(71010..72167)
                     /locus_tag="ACIZD4_000064"
     CDS             complement(71010..72167)
                     /locus_tag="ACIZD4_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HGC5989036.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72201..73571)
                     /gene="radA"
                     /locus_tag="ACIZD4_000065"
     CDS             complement(72201..73571)
                     /gene="radA"
                     /locus_tag="ACIZD4_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGC5989037.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73634..74161)
                     /locus_tag="ACIZD4_000066"
     CDS             complement(73634..74161)
                     /locus_tag="ACIZD4_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGC5989038.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74391..75197
                     /gene="proB"
                     /locus_tag="ACIZD4_000067"
     CDS             74391..75197
                     /gene="proB"
                     /locus_tag="ACIZD4_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGC5989039.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKIVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75194..76441
                     /locus_tag="ACIZD4_000068"
     CDS             75194..76441
                     /locus_tag="ACIZD4_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGC5989040.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76517..76861
                     /locus_tag="ACIZD4_000069"
     CDS             76517..76861
                     /locus_tag="ACIZD4_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989041.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76978..77304)
                     /locus_tag="ACIZD4_000070"
     CDS             complement(76978..77304)
                     /locus_tag="ACIZD4_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989042.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77919..79121)
                     /locus_tag="ACIZD4_000071"
     CDS             complement(77919..79121)
                     /locus_tag="ACIZD4_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5989043.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGIKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79238..79753
                     /locus_tag="ACIZD4_000072"
     CDS             79238..79753
                     /locus_tag="ACIZD4_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC5989044.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79952..80398)
                     /locus_tag="ACIZD4_000073"
     CDS             complement(79952..80398)
                     /locus_tag="ACIZD4_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HGC5989045.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80445..81923)
                     /gene="msr(C)"
                     /locus_tag="ACIZD4_000074"
     CDS             complement(80445..81923)
                     /gene="msr(C)"
                     /locus_tag="ACIZD4_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HGC5989046.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82277..82906)
                     /locus_tag="ACIZD4_000075"
     CDS             complement(82277..82906)
                     /locus_tag="ACIZD4_000075"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGC5989047.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82890..83354)
                     /locus_tag="ACIZD4_000076"
     CDS             complement(82890..83354)
                     /locus_tag="ACIZD4_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC5989048.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83841..85109)
                     /locus_tag="ACIZD4_000077"
     CDS             complement(83841..85109)
                     /locus_tag="ACIZD4_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HGC5989049.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85340..86077)
                     /locus_tag="ACIZD4_000078"
     CDS             complement(85340..86077)
                     /locus_tag="ACIZD4_000078"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC5989050.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86144..86713)
                     /locus_tag="ACIZD4_000079"
     CDS             complement(86144..86713)
                     /locus_tag="ACIZD4_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HGC5989051.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86841..87713
                     /locus_tag="ACIZD4_000080"
     CDS             86841..87713
                     /locus_tag="ACIZD4_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC5989052.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            88055..88927
                     /locus_tag="ACIZD4_000081"
     CDS             88055..88927
                     /locus_tag="ACIZD4_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC5989053.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88924..90882
                     /gene="nagE"
                     /locus_tag="ACIZD4_000082"
     CDS             88924..90882
                     /gene="nagE"
                     /locus_tag="ACIZD4_000082"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HGC5989054.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91214..92065)
                     /locus_tag="ACIZD4_000083"
     CDS             complement(91214..92065)
                     /locus_tag="ACIZD4_000083"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC5989055.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92188..92655
                     /locus_tag="ACIZD4_000084"
     CDS             92188..92655
                     /locus_tag="ACIZD4_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGC5989056.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92918..93400)
                     /locus_tag="ACIZD4_000085"
     CDS             complement(92918..93400)
                     /locus_tag="ACIZD4_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC5989057.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93500..94363)
                     /locus_tag="ACIZD4_000086"
     CDS             complement(93500..94363)
                     /locus_tag="ACIZD4_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC5989058.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94961..95836
                     /locus_tag="ACIZD4_000087"
     CDS             94961..95836
                     /locus_tag="ACIZD4_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HGC5989059.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95981..96133)
                     /locus_tag="ACIZD4_000088"
                     /pseudo
     CDS             complement(95981..96133)
                     /locus_tag="ACIZD4_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96401..97732)
                     /locus_tag="ACIZD4_000089"
     CDS             complement(96401..97732)
                     /locus_tag="ACIZD4_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC5989060.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97881..98594)
                     /locus_tag="ACIZD4_000090"
     CDS             complement(97881..98594)
                     /locus_tag="ACIZD4_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5989061.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98769..100193
                     /locus_tag="ACIZD4_000091"
     CDS             98769..100193
                     /locus_tag="ACIZD4_000091"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC5989062.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100492..101199
                     /locus_tag="ACIZD4_000092"
     CDS             100492..101199
                     /locus_tag="ACIZD4_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGC5989063.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            101186..101509
                     /locus_tag="ACIZD4_000093"
     CDS             101186..101509
                     /locus_tag="ACIZD4_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGC5989064.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101598..102635)
                     /locus_tag="ACIZD4_000094"
     CDS             complement(101598..102635)
                     /locus_tag="ACIZD4_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC5989065.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(102956..103939)
                     /locus_tag="ACIZD4_000095"
     CDS             complement(102956..103939)
                     /locus_tag="ACIZD4_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HGC5989066.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104354..105124)
                     /locus_tag="ACIZD4_000096"
     CDS             complement(104354..105124)
                     /locus_tag="ACIZD4_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989067.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(105117..106052)
                     /locus_tag="ACIZD4_000097"
     CDS             complement(105117..106052)
                     /locus_tag="ACIZD4_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989068.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(106368..108017)
                     /locus_tag="ACIZD4_000098"
     CDS             complement(106368..108017)
                     /locus_tag="ACIZD4_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGC5989069.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(108134..110737)
                     /locus_tag="ACIZD4_000099"
     CDS             complement(108134..110737)
                     /locus_tag="ACIZD4_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGC5989070.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(110749..111798)
                     /locus_tag="ACIZD4_000100"
     CDS             complement(110749..111798)
                     /locus_tag="ACIZD4_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGC5989071.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(111824..112138)
                     /locus_tag="ACIZD4_000101"
     CDS             complement(111824..112138)
                     /locus_tag="ACIZD4_000101"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGC5989072.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(112154..112600)
                     /locus_tag="ACIZD4_000102"
     CDS             complement(112154..112600)
                     /locus_tag="ACIZD4_000102"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HGC5989073.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(112601..114523)
                     /locus_tag="ACIZD4_000103"
     CDS             complement(112601..114523)
                     /locus_tag="ACIZD4_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC5989074.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(114735..115631)
                     /locus_tag="ACIZD4_000104"
     CDS             complement(114735..115631)
                     /locus_tag="ACIZD4_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC5989075.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(115624..116304)
                     /locus_tag="ACIZD4_000105"
     CDS             complement(115624..116304)
                     /locus_tag="ACIZD4_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC5989076.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(116305..117087)
                     /locus_tag="ACIZD4_000106"
     CDS             complement(116305..117087)
                     /locus_tag="ACIZD4_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC5989077.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(117080..117997)
                     /locus_tag="ACIZD4_000107"
     CDS             complement(117080..117997)
                     /locus_tag="ACIZD4_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGC5989078.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(118161..118415)
                     /locus_tag="ACIZD4_000108"
     CDS             complement(118161..118415)
                     /locus_tag="ACIZD4_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989079.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
     gene            119272..122499
                     /gene="fss3"
                     /locus_tag="ACIZD4_000109"
     CDS             119272..122499
                     /gene="fss3"
                     /locus_tag="ACIZD4_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HGC5989080.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            122612..122926
                     /locus_tag="ACIZD4_000110"
     CDS             122612..122926
                     /locus_tag="ACIZD4_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC5989081.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            122939..123313
                     /locus_tag="ACIZD4_000111"
     CDS             122939..123313
                     /locus_tag="ACIZD4_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC5989082.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            123323..123658
                     /locus_tag="ACIZD4_000112"
     CDS             123323..123658
                     /locus_tag="ACIZD4_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HGC5989083.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            123741..125081
                     /locus_tag="ACIZD4_000113"
     CDS             123741..125081
                     /locus_tag="ACIZD4_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGC5989084.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            125159..125833
                     /locus_tag="ACIZD4_000114"
     CDS             125159..125833
                     /locus_tag="ACIZD4_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HGC5989085.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            125826..125990
                     /locus_tag="ACIZD4_000115"
     CDS             125826..125990
                     /locus_tag="ACIZD4_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989086.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            126066..127208
                     /gene="dcm"
                     /locus_tag="ACIZD4_000116"
                     /pseudo
     CDS             126066..127208
                     /gene="dcm"
                     /locus_tag="ACIZD4_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            127198..127488
                     /locus_tag="ACIZD4_000117"
     CDS             127198..127488
                     /locus_tag="ACIZD4_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989087.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            127747..128931
                     /gene="mobT"
                     /locus_tag="ACIZD4_000118"
     CDS             127747..128931
                     /gene="mobT"
                     /locus_tag="ACIZD4_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HGC5989088.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            128928..129065
                     /locus_tag="ACIZD4_000119"
     CDS             128928..129065
                     /locus_tag="ACIZD4_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HGC5989089.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            129811..131721
                     /gene="ltrA"
                     /locus_tag="ACIZD4_000120"
     CDS             129811..131721
                     /gene="ltrA"
                     /locus_tag="ACIZD4_000120"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGC5989090.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            131825..132049
                     /locus_tag="ACIZD4_000121"
     CDS             131825..132049
                     /locus_tag="ACIZD4_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989091.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            132062..132565
                     /locus_tag="ACIZD4_000122"
     CDS             132062..132565
                     /locus_tag="ACIZD4_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HGC5989092.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            132625..133014
                     /locus_tag="ACIZD4_000123"
     CDS             132625..133014
                     /locus_tag="ACIZD4_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC5989093.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            133001..>134475
                     /locus_tag="ACIZD4_000124"
     CDS             133001..>134475
                     /locus_tag="ACIZD4_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5989094.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGG"
BASE COUNT        39015 a        27858 c        24422 g        43180 t
ORIGIN      
        1 agagtgtttc ccgattcatt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagcgattgt caactctttt ttaaaagttt ttttcgattt cgtttttcga aatctttcgg
      121 caactcattt atcataactt atcgtttgtt atttgtcaag aacttttttg aagttttttt
      181 cgatagaatc aagcttcgca agtggttctt ttttaacgac tcagttatct tatcatgtcg
      241 ttagtaacat gtcaataact tttttgttat gtttttgaat aaatattttc ttctgtcttt
      301 tggacaagta ataatatacc aactaaattt agcttggtca acgaattttt tgtatttttt
      361 caagtttttt tcaataaacg attattcata acttttcttt ctttatcgtt cgttttcgtc
      421 ttctttaatg tctagaatag tcggcattag cttttgaact ttcgttatta tttattcctt
      481 tctacacagc aaaagctgcc taaggaattc cttagacagc ttttattcga ttatctcatt
      541 gttgggaata gcaaaacatc ccgaattgat tgtgcatcag ttagcaacat tactaatctg
      601 tcgatcccga tgcctagacc accagttggc ggcataccgt attctaaggc ttccaagaag
      661 tcttcgtcta caccgtgagc ttcgtcattt cctagttcac gttctttttc ttgcgcttcg
      721 aatctttctc tttgatcaat tggatcgttc agttctgtaa aggcattagc aaattcgcgc
      781 cccactatga atagttcgaa tcgatctgtg aatcgaggat cttctggatt tttcttcgct
      841 aaaggcgaaa cttcgactgg atgtccgtat acaaacgtcg gttgtgtcaa tgtttcttca
      901 acaaatgttt caaagaattc attgataaca tgtccgacac ccatagcttc ggttacttct
      961 acattgtgtt tttcggctaa agctaatgct tcttccaatg tcatttcttg ccagaagtct
     1021 acaccagttt gttctttgat tgcatctacc atatggatgc gtttaaagtc actttctaag
     1081 tcgacagctt gtccatcata tgtgattttt gctgttccta gtactttttc agctgcgtta
     1141 cggataatac cttctgtcag attcattaca tcattgaaat cagtatatgc tgtgtatgct
     1201 tctaacatcg taaattctgg attatgtgta gtatcaattc cttcattacg gaaaacgcgg
     1261 ccgatttcat aaactttttc cattccgcca acaattagtc gttttaaatg aagttctagc
     1321 gcaatacgca aatataaatc aatgtccagt gcattatgat gcgtgataaa tgggcgtgcg
     1381 gcagctccac ctgcctcatt gtgcaatact ggtgtttcta cttcaatata gccattgcca
     1441 tctaaatagc gacggatttc gctgataatt tggcttcgtt tcataaatcg gtcaaagctt
     1501 tcgcgattac tgattaaatc caagtagcgt tgtctgtagc gttgttcaat attcgttaag
     1561 ccatggtatt tatctggcag tggacgaagt gcttttgaca aaatcgtgat ttctgaagct
     1621 ttgatagaaa cttcgcctgt gtctgttttc atgatttgtc cagttacacc aaagaaatct
     1681 ccaaggtctg catgtttgaa tacttcatag gcctcatcac ctacttggtc ttttcttaca
     1741 taaatttgaa tttggccttc acgatcttgt agatgcgcaa atccagcttt cccttttcct
     1801 cggcgagtca tcatacgacc agctacacta gcggtcaatc ccatttctgc tagttcttct
     1861 tttgttcttg gatcaaatag ttcatgcaat tcttctgagt tgtgcgtgcg ttcaaatcgt
     1921 tttccaaatg gatcgattcc atcttcacgc aattgttcca ttttttgacg acgtacaagc
     1981 atttgatcat ttaaatcttc tacttgatgt tgttgttcct gtgtcacaaa agttcctcca
     2041 ttctcatgtt aatctctttc ctataatgcc aatgaaacac aaaaaaagca agccgaactt
     2101 ggaatttcgg cttgaaaatt cacgaaaaac ttagaaatca caacgtttgt ttcaatagta
     2161 ctttttccgc tttttctaca aattgatcca gcaggtcatt gatttcttgc tgtttttctg
     2221 tctgattgat tgctactttc actttcgctg ctcgaggaat cccttttaaa taataagccg
     2281 catgtgttct gaattctcta caagctactt tttctccttt gagatctgct aagcgttgta
     2341 aatgaagttt agctgtagca attttttcgg ctggtgttgg ttcaggaatc agttcccctg
     2401 tttcgagata atgctgtgtg cggtgaatca tccatggatt gcccagcgct gcacgaccaa
     2461 tcatcacacc gtctgcaccg acatagtcaa gcatccattt tgcatcttct ggcgttttga
     2521 catccccgtt ccccataaat ggaatcgtca aatgtttttt cacttctttc aatacttccc
     2581 agtccgcttt tccttcatac atctgaaccc gtgtacgtcc atgcatagcg atggcacttg
     2641 ctccagctga ttgtgctgct aatgcatttt ctacagcaaa gacgtgctct tcatcccaac
     2701 caatacgcat cttgattgtt actgggatat ttactgctga agaaacagct tggaccattt
     2761 cgtatacttt ctcaggatct aaaagccatt ttgctcctgc ttctgctttg attactttat
     2821 ttactggaca gcccatattg atatctatta tatcggcagc tgtgttttct tcgacaaatt
     2881 gagcagcttc aactagacta tctttatttc cgccaaatat ctgtaaactt aatggatgtt
     2941 ctgtttcttc aatgtggagc atctctaaag tttttttgtt tctgaaatga ataccttggt
     3001 cactgatcat ttcacatacg actaagcccg caccaaattc tttgacagtg actcgaaatg
     3061 ctgaatttgt tattccagcc atcggtgcaa caacgacacg attagggatt tccacattgc
     3121 caattttcca tgtgtgttcc acttaaatcc ctcctaaggc ttctttcttc aatccatcta
     3181 attcttcttc gctatacttg tatttgttat tacagaaaga acaaaccgct tctgcaccgt
     3241 gatcttcgtc tatcattgct tggatttctt ctgcacctaa cgcgataatt gcttctgcaa
     3301 atttttcttt tgaacagtca catttgaatt gaacaggcat tttttccaaa atgttcaatt
     3361 cttctgtacc aagcaatcct ttcaatattt cttctggtgt ctgtccttca tctaagaggg
     3421 tagagattct tggtgtcgtt tttaattgtt cttcgatctt gctgattgtt tcttcatcgg
     3481 cacctggcat gatttggatc atgaatcctc ccgccgtctt gatgctgtcg tcagtattga
     3541 ccaatacact cagtccaaca gctgaaggga tttgttctga gatagcaaga tagtaagtaa
     3601 aatcttcagc gatttctcca gaaacaatcg gcgtttgccc agaaaaaggt tcttttaatc
     3661 ctaagtcttt tgtgacagta aacattcctt gtgttccaac tgctccccgc acatcgattt
     3721 taccttcact atttagagga agactgagat gcggattttt gatgtaacct ttcacatctc
     3781 cctttccatt tgcatctact acaattcctg ttgctggacc atcgccttgg attcgaacag
     3841 ttagtttgtc ttctcctttg agcgtcgcac caagtagcag actaccgacc aatgtccgtc
     3901 ccaaagcagc tgaggaggtg tgccaagtat catgacgtct ttgtgcctcc gctacggtat
     3961 ttgttgcttg aacggcgtat gctcggacga atccgtcgtg agcaagtgcc ttaaccaaat
     4021 aatctttcat ttgttatgta ctcctttttc cgtttttaaa ctcatagtga atcatactag
     4081 caactactgc ttttttcaac tttggaatgc ttcttttaaa aataattcag aatcatctag
     4141 aaaacaggac atcaccctat ttacaactta aataaagaaa tctcccgaaa accggttttt
     4201 gttccggttt tcgggagtca tatcagatca attgacctat atttttttat ttgtattgat
     4261 cgtctgaatg attatcttct gattgttgag aatctgaatc atgttctgct ttattttcct
     4321 cattcagttc atgttttgct tcttcaaaat cacgtttttc ttccgcttgt ttttcagcgt
     4381 ctttttcttc caaagcacgt tttgcttctt caaaagtttt cgcttctttt tcgcttggat
     4441 aatcatttga ctcagtacct tcaggcatca caccgtgttc aaacaatgac ttgattgctt
     4501 tggcatccaa tgtttcgaat tccaaaagtt tttcagcaat cagtttatgc tgtgcacgat
     4561 gagcttcgat gatttctcga gctttatcat gagcttccat caagattttt cgtacttctt
     4621 gatcaatctc gaaagcgact tgttccgagt aagcttttgt ttgaccatag tcgcggccaa
     4681 caaacacttg atggtttcct tcatattgaa caggacctaa acgatcactc attccatatt
     4741 ctgttaccat gcttcgtgct agagctgtcg cttgctcaaa gtcattggaa gcaccagttg
     4801 attggacatt gaagatgatt tcttcagctg tacgtccacc aagtaagcct acgatttgtt
     4861 caaacatatc ttctttcgtc atcaagaact gatcttcttt tggtaaagcg atcatatatc
     4921 cgccggcgcg tccgcgaggg atgatcgtta ctttgtggac gacccgagcg cgactcaata
     4981 ctaatccgac aatcgtatga ccagcttcgt gataagcaac catttcgcgt tcttttttgc
     5041 tgattacgcg atctttttta gctggacctg caatcacgcg atcttccgct tcatcgatat
     5101 cagaagcatc gattttcttt ttatttcttc tagcagctac taacgctgct tcattcaaga
     5161 cattttctaa atctgctccg gcaaaacctg gtgtctgttg agccacaact ttcaagtcaa
     5221 cgtcatctgc catcggttta ttccgtgcat ggactcgcaa gattgcttca cgacctttta
     5281 catctggacg tccaactaaa atctggcggt caaaacggcc tggacgtagt aacgctgggt
     5341 ctagtacatc agaacggttg gttgcagcaa tgacgattac tccttcattt ccgtcgaagc
     5401 catccatttc tacaagcaat tggttcaatg tttgttcgcg ttcatcatgt ccgccgccca
     5461 taccggcacc acgttgacga cctaccgcat caatttcatc aatgaaaatg atagctggtg
     5521 cgtttttctt cgctgtttca aacaaatcac gaacacgact tgctccaaca ccgacaaaca
     5581 tttctacgaa atcagaaccc gagatcgagt aaaacggtac tccagcttct ccggcaacag
     5641 cttttgctaa taaggtttta cctgttcctg gaggtccttc taaaagtaca cctgccggga
     5701 tacgggcacc taattcaaca aatcggcgag gatctttcag aaattcaaca acttcaacta
     5761 gttcttgttt ttcttcttcc gcacccgcta catcagaaaa acgtacgcga ttagcttttt
     5821 tgtctgcttc tttggctttt gatttaccaa agttcatgac acggccgcca ccgccaccgc
     5881 cgccgccttg ttgtcccatc atcatgtaaa agaaaaagat gatgattacg attggcaaga
     5941 agctaagcaa tagggaaacc catataccgc tgcttgattc ttcttttact gttgtagcaa
     6001 ctttgttttc ttttgccagt tctgttactt ggctcaatgt tgtatcattt ggcaaaatga
     6061 ttgttgtgaa atgggtagta gtcgtatctg ttgaacctaa gatagctaac ccaccgctgt
     6121 tagcgacggt ctgctgttct ttgtattcac cagtgatctt atatacacca tttgcaggct
     6181 gcacttcaaa ttctttgatc ttgcctgctt gtagttgttc tgtgaatttt gagtactcga
     6241 tatctgacga tcgctggccg ttattaccaa aaatgaaata aacgaccatt accatcgcta
     6301 agattacgag gacataatac aaggcatttt tcatcatgcc gttgttcttt ttgttcatag
     6361 ttgccctccc taagcgtcaa tttaatttaa cagtttttta tcaatcctga ccattctatt
     6421 gtaccataat ttaattgaga tacagcatta atttgattga taaacactag gtttcaatac
     6481 accgatgtac ggaaggttac gatatgcttc tgcataatcc aagccataac cgaccacaaa
     6541 ttcatttggt acgttgaagc caacataatc tgcttcgata tttactactc ttccttcagg
     6601 tttgtcaagt agtgtaacaa ttttgactga ttttgctttg cggtatttga aaagatccac
     6661 taaataagca agtgttcttc cgctgtcaat gatatcttca acgatcaaca gatcgcgacc
     6721 ttctacattc gtatctaagt ctttgacgat ttttacttcc cctgacgaga ctgttgcatt
     6781 cccgtagctt gaaacatcca tgaaatccaa ttccaaatac gtatcgatag aacgaacgat
     6841 atctgccatg aatggtaccg ctccttttaa gacacctact actaggggat tggtgttttg
     6901 gtaaatttct gttaactctt tgcctagttc tttgcaacga acttgtatct cttcttgtga
     6961 gatcaaaatt ctctcaatat ccttttccaa catcaggttc tccttccaat tgcttctttt
     7021 tgatatttgt aaagaagtat gtagtgtatt ttatcagttt cttcacgaat actcaaatat
     7081 gaaaaggcaa aaggtatcaa gctatatata tttcttttgg catctgtaat gatccaagca
     7141 tgctgccttt gtgaattagg tactttctga tcgataaaat atctagatac tttttttgtg
     7201 agattctctg ttaatttaat gcggtctcct gcttttcttt tttcgacata cagttgcaca
     7261 tcagcaggaa tccaaatgtc atgagaaaat agagaccatg aatctgttgc tttgatgtcc
     7321 cctgcatttt caggtttgac cagaccaatc cattctgttt cattcaaata tattccttgt
     7381 tctggaatca gcaacaagcg ctggtcttct gtctggctag ttgcttgttt ttctttttta
     7441 gagagtacaa caaaatgata ctctcttttc agtatccaat tattgccaat actgagttgc
     7501 cattggcttt ttttctgttg ccactggtct aaaatcgact ccatttgttg ttctttcaaa
     7561 ataattcctg tttttgagaa tgctttgtcg aaaaaggagt aaaaaaaata gtatcgttca
     7621 gcatctgtca tttcttcaat catttctgca gaaaatcgaa attgttcctc ccactgttcg
     7681 acttcctttt cgatcaactg tcccatatat ttttgaatga cttggtctgc ccattggatc
     7741 tgttgcgaaa attgctggaa atgtctcaac gcctgtgtat tttcttgttt caattgagga
     7801 actaccaaat gacgaagccg atttctctgg atatctaaca attggtttgt ctgatcctca
     7861 aagtaaacaa gctgcgattc cgctgcataa gtatataggt cttctttgct aaaactcagc
     7921 aacggacgaa tcagtctgcc cgtagcaaat ggttgtactt ctttgattcc agaaaaagta
     7981 tttaactgtc ccccacgaac gattttcatt aacaccgtct cgatttgatc atctccgtga
     8041 tgagcagtca tcaacgtgtc atattgtcct tcttccatca cgcgagtgaa ttcttgataa
     8101 cgaaagttac gagcttctgt ttctatggcg gatttggctg gatcttccca aatacttaca
     8161 tataaaggga gattcttctc ttcacaatat gagcgaagat aggcagcttc ttctgctgat
     8221 tcttctctta attggtgatt gatgtggacg atacctaaag aaaaaccgat ttggcgttgc
     8281 acttgtaaaa gtaaatggag caaaaccatc gaatcaacac cacctgatac cgctgctaaa
     8341 attctcgatc cttgttgcca gaatccttgt tcattcccgt gccgaataaa tgactgctgt
     8401 aatagcggtg cttttttccc gcctttttca acgttcatcc tttccacacc ctttcttcct
     8461 aaaaaaaaga gagcgggaaa acgtctaaaa cgacaattaa cctgccctct gttgatacta
     8521 tgacccaaat agtcgcacta tcattatttg cggcttttta gctgcgacgt ccgccacggc
     8581 caccgcgctt tccttctgtg tttcgcttca atgaagataa gcggtcatcg ctatctttca
     8641 aaaatgaact catcaatgaa tcgaagtctt ctttttgagc tgaaggttga ctgcgagaaa
     8701 aagatttttt ctgtgctgga cgatttcggt tgtcacgggg atctttttgt tgatattttt
     8761 taggacggct ttcttctcca gattcagcag gttgttcctg cgctttccgg atagatagtc
     8821 cgatttttcc atcatcattt actgaaataa ctttaactgt tacttcatct cctacactta
     8881 aaacatcatg gatgtctttt acatagccat ttgacacttc gctaatatga actagacccg
     8941 tttttccagc acctagatca ataaacgcac caaaatttgt gattcctgat acttttcctt
     9001 gcagttttgc tcctacctcg attgacataa aaaaaatgtt cctcctaatt atttcccttt
     9061 tttatattcc tgcttatttt gcagttgtag aactagttga ttgatctgtt tcatttgtcg
     9121 agctgtctgt atttgattct aatataggat aaactttttc accgtctttt gagtaaaaga
     9181 atttgcttct ggcaagttta gctacatact catcatcttt cagcaatgaa acatcttggt
     9241 gcagctgatc aacgtctgcg ttgacttctt tcatttcagt atttgcttcg actctcaatt
     9301 cgttcaattg atgcatcctt tgcatgtcat ggaaaatctg cacacctatt atcgcgaaaa
     9361 tgaccaaagc accaacaaaa attgcagcca gtctgcgtct tcgaaaaatc agttgacgtt
     9421 gttgttgctg aaattcagca tactttttct ttgcatattc cgtatctagc gcagcgattt
     9481 tattgctttt tttcgtcact tggattcgct ccaatctttt tgattgtctt tttcattata
     9541 ccaatatcgt gaaagcttgt ctaatctatt tctctagtgt ttctgtgcga ttttcagaaa
     9601 taatttcgta cattttttgt gcatcttctt ttttggttga ttcatgtaat tccgtaattt
     9661 tcacttccaa cgttttgttg ccaaactgga ctttcaaaat atcgcctact ttgacatcac
     9721 tggaagattt cgccaattta ccgttgattt gaattcttcc tttatcagct acttcttttg
     9781 ctactgatcg tcttttgatg attcgggaaa tttttaaaaa tttatctaat cgcatatctt
     9841 attcctcact ttttaatttt tttatttaat cgcaggattt tcttaccaaa aggcaacatt
     9901 agccattctc gtactgtaaa cagacgaaga cgaatcactg cataaatgaa cacagaagcc
     9961 ccgatcccaa ctcctatcac gctgacaaaa aaagcagtgg aacgatgagt tacaggacca
    10021 aatactatat tcaatacacc ataatacagc agcagtacta ctgtcataca aagaaggctg
    10081 aacatcaact tccgtccaaa atgccgttct ttccaaaaag catttagctc ttttgtttca
    10141 attcgaacaa aataccaaag cgtcacacct aatcctaaaa gggtagacag gcttgcacct
    10201 gctgttccta ataaaccggt cagaaaagaa gtagtcaatc cttttaccaa tagtccccat
    10261 cctgcgcctt ttaaagaagg gcgaaacgag ttcttgcttt gagcaatact ttgataagct
    10321 tggatgactg cagtgaaagc aatggaaaaa acaaataata caagcgctgc atttcccgca
    10381 taatctttaa acaacgcata attgatataa gggagcagca aggctaatcc caaagacgca
    10441 gctaatgcta aagcggtcgt caatctaaga tagattttgg ctgtctgtaa aaactgacga
    10501 tagatccggt tggtcaaatg acgagtcaac gcaggcagga atgtcgcact taatgcagtg
    10561 gcaatcacta aacctaattg tactaaaggc tgacctcgat catagacccc ttttgctatc
    10621 ttcgcaccgt attctgacag tccgtaaact tccaaagcat tttttacaaa gaaagagtcg
    10681 atcagctgga aaaagataag caatccacta taaatcgaaa ccagtccgcc ttctaccaga
    10741 aaacgccgga tcaagggctt tgacggctgt ttgaacaatg gaaaccgtcg gaagcttaac
    10801 gctcctccat gaatcttttg ttcatagtag tgaaggatcc catatgcgca taaaccgcca
    10861 aaaacagctc cactcattgc tgccgtccct gtttggtaca ccgtccatcc aagctttcta
    10921 aaagcaaacg cactacagac aatcacaaaa acacgaacga actgctcaac tacttgagaa
    10981 acagcagttg gttccatcaa gaatcttcct tggaaattcc ctcgataaaa agatagacca
    11041 ggcatcagca aaaaggtaaa ggaaactact tggatcagcg gtttcaattg tatgtctccc
    11101 atcatccaag caatccagct gctaaatgca aagacaaaca accacaaaaa gacacctgtc
    11161 caaaatacta agggataaag attttgcaaa gcttgctttc gctcgaaagg attctttctt
    11221 tctgcaacgt actttgatat gaactgcgga agaccggata aagctaaagt cattgctatc
    11281 ccataaattg gataaacttg ctgataaaca taaaaacctt cgtcgccgac taagttttgg
    11341 aggggaattc ggtaaagggc acttaatact tttgctatga aagaagcaat cgtcaataca
    11401 aatgctcctt gcatgacgcg ccgcatttct ttatgatcca aatcattgct ccttcctacg
    11461 ctgacagata tttttgctca cgcaacgctt tgacaaactt ttggatttcc tgaagccata
    11521 ctgcttcttc catttggttg gggatcgtca agcgtatcac catctgttct ttttcaacgc
    11581 ctagactggc ttttagtttt gtcgctgtca gtgcttcgaa taactgttcc acactatagc
    11641 gttttgttcc aactttactt agagtaaaga ctatatgcgc ctcctgtttc cttatcgttt
    11701 ctaggagcgc tcgatcgcca tccattttga tctgcccaat tgtcaagaga tgtgctactt
    11761 cttctggata ttctccaaaa cggtcgagca gatcatcttc tagttcatct agcatttctt
    11821 gcgaatcaag ttcacgaatt cgtttataga tctcgatttt ctgccgttga tctgccacgt
    11881 atgtttcagg tagatacgca tcgacaccga ggtcgatctc aacagtggtc ttctccactt
    11941 gactattctt tccttgttta cgagaaacag cttcgcttag catttgagaa tacatatcga
    12001 aaccgactgc atcaataaat ccatgctgct gagcacctaa gagattacct gcaccgcgaa
    12061 tggaaagatc ccgcatcgca atcttgaatc cagatcccag ttctgtaaaa tctttgattg
    12121 cctgaagacg tttttcactg acttcgttaa ggatcttctg ctgctcatac ataaagtaag
    12181 catatgcgac acggctgctt cttcctaccc gccctcgcaa ttggtataac gtggataatc
    12241 ccatataatc agcgttctca acgaacaacg tatttgcgtt cgggatatct actcctgttt
    12301 caatgatggt tgtagtgaca agaacatcat attgaccttc aataaattca aaaagcgtat
    12361 tttctaattg cgcctctgtc atttgcccat gagcataacc gatccgtgct tccggaacga
    12421 gttcttggat ttcttctact ttttgttcga tcgtttctac ccgattatat aaatagaata
    12481 cttgtccacc tcgtcccatt tctcgatgga ttgcttcgcg aatagcccca ggattttttt
    12541 ccataacata cgtttggatc ggataacgat tcgcaggcgg tgtttcgatt actgaaagat
    12601 cccgcacgcc taacatcgac atatgcaaag ttctcggaat cggtgttgca gtcagagtca
    12661 aaacatccac ttgtgcacgt aactgtttca atcgttcctt atgttttaca ccaaaacgtt
    12721 gttcttcgtc aatgatcagt agacccaaat cgctaaattc aatatctttt gacaaaattc
    12781 ggtgggttcc tacaacaata tcaacttgac ctgtacgcag ttgttcgatg gtttcttttt
    12841 gttgctttct tgttctgaaa cgacttaata gcccgatatt tacggggaaa ccttcaaatc
    12901 tttccagcat cgtttcatag tgctgctgtg ccaagatcgt tgttggaact aaaaaggcta
    12961 cttgtttgct ttcctttatc gctttaaagg ccgctcgaag cgctacttct gttttcccat
    13021 aaccaacatc acctacgagt agtcgatcca ttggtttttc tttttccata tcccgtttga
    13081 tctccgctgc acttctcaac tggtcatcag tttcagagta ggggaaggca ttttcgaatt
    13141 ctttttggta ggcgtcatca ggtccaaaag catatccttt ttctgactct cttgcggcat
    13201 ataatttgat tagatcgtca gcgatatcct cgatttttga agagactttt cgcttggttt
    13261 tcgtccattc acttccgcct agcttattga tgcgaggcgc tttggcttca gaggcgacat
    13321 atttttggat cagattcagt tgagtaacag gaataaacag tttgtcgtcg ttttgataca
    13381 aaatagtcat atagtcttgg tgaacgccat ctacttctag cgtttccatc ccaatgtatt
    13441 tcccgatacc atgattggca tggacaacgt aatctcctgc ttttaactca ttatagcttt
    13501 tcaatcgctc tgcgtttgtt actgtttgac gtctcgtttg ttttttcgtc gttttttgga
    13561 aaatttcttt ttctgtgata gctactattt tttcttgagg aagttcaaaa ccagcctgca
    13621 aagctccttc aactaattgt acctgtcctc tgatcaatgc atttttttct gtttctacta
    13681 ctaatatgtc ttcatctcga agcatttgtt ctgctttgcg tattctgtcc tttgtcggaa
    13741 taaagatcac aacagtctgt ttttgcttgc gccaacggtc catttctgtt ttcagcaatg
    13801 gcatttgtcc gaagaactgt tgcatcgtcc gatattgaaa attatggatt gcttggaaac
    13861 gaagatttcc catccctttt tggaagagtg agaaaaaggt tgtggtgaac ttttccttct
    13921 gcacgatttt ttgtatatct gctgaaaatg tctgctcaga aaacacccgc aattcgctga
    13981 ttttttgagt ctgccattct gccgcttccc tttcgatttc ccgatttgtt tccatgattc
    14041 gctgataatc atcaacgact agtaaactat ttgaagggaa ataatccaag atcgtcacag
    14101 attcttggta aagaagatct gagtagaatt ttgcttcttc tgtcgggaca cctgcttgcc
    14161 agcttgaagt cagctgaccg aagtaatctt gcaaaaactc gcggtctgct tcttctgtgg
    14221 tcgcagcaag ccgtttttct agcatttttt gcatttgctc tattccatgt tctagatcct
    14281 ctggtccgta gacttgttca ctcgttgggg aaacccagat ttcttccgtt ttttcgattg
    14341 agcgttgtgt ttctgcttca aaataccgca tagaatctat ctctacatca aatagttcta
    14401 cacgaacagg ataggttgtc gttaacgggt aaatatcgat aatgcttcct cgaatactga
    14461 attctcccgg ttttgcgacc atctcttctc gtacatagcc catcaaagtc aattggcgag
    14521 gaagattttc cacgtctatc tcatcaccaa tatgccaatt caattgcgcc tgtagccaag
    14581 ttttcttatt cggcagtcgt ttgtgcaaag atgcgactgg caacaaatag atacctgctt
    14641 ttttttcttg aagtgcgtta agcgttgcaa ctctctcgcc tcgcgcttct ggagaagaaa
    14701 aggccatttc agcagaaagc acttcatcca ctggaaataa atggatctga tcttgcggaa
    14761 tcacatgttg cagatcttct gctaactgat tcgcataata caaatttggc atcagaataa
    14821 tcatgttttt atttgttttc ttaaacgctc gagcaaatag aagtgttttc gctgagcccg
    14881 ctaatcctgt gattagttgt ctaggcattt tttcttctaa attgctgacc cattctttta
    14941 cttgcggatc ttttccgact aattgaataa tatccattcc ttttcctcct tcctcaattg
    15001 aatcgattca tcgcatccac gaacgaatgc ccttctatga gatattcgac tgctttaaca
    15061 gattgacaca tgctttcttc tatcaaaggc tgattttctt tgctgaaagg actaagcaca
    15121 tgctggacta ctgttttttt cccttctggc ctgccgattc ccaccttgat tcgatcaaag
    15181 acattcgtat tcaaatggga aataatactt ttgataccgt tatgcccgcc ggcacttccc
    15241 ttttgacgga gccggatttt tcccactgcc agatccaaat catcgtagat tacgactaat
    15301 tcctctggat aaatcccaaa ataagtcatt agtgggccga ctgcacgacc agattcattc
    15361 atgaatgttt gtggtttgac taaaaggatc ttttctccat tatgaaaaaa ttcggcaact
    15421 tctgcttcga acggattttt tttgaaagta gcttgatgct cgcgtgcaat tttatccacg
    15481 accataaagc cgatattgtg ttttgtatat tggtatttgg tacctgggtt tcctaacccg
    15541 acgatcattt tcatttttgt tttccaccta attctaaaaa gcagcacaaa aggctggact
    15601 gctaattagc ggtccagtcc atcgagcttt tttctttttt acacttgtca atgcatagta
    15661 taacacaaaa caaggcgttt cggctaaaag agaatcgtta ataaatgata aagaaattaa
    15721 aaatttcttc aaagtttaat gaaataattg atatataaaa atagtgaaat aacgcacatg
    15781 taagctttta catataatac aaccttgtta tctgttatat tttatagcca aatagcgtga
    15841 catggggctt gagaaatgtt agcataagca tgggaaaaaa caaatcaatg gaaggattga
    15901 tactaaatga ctgcagctgc agaaaaaaaa gatcatcaaa aagttattct tgttggagac
    15961 ggcgccgtag gttctagcta tgcctttgct ctagttactc aaaatatcgc tcaagaagta
    16021 ggtattgtgg atatcaatac tgctaaaact gaaggagacg caattgactt gtctcacgct
    16081 ttggcattta cttcacctaa aaaaatctat tctgctactt acgcagacgc acatgatgct
    16141 gacttagttg ttattacagc tggcgcacca caaaaaccag gtgaaactcg tttagactta
    16201 gtaaacaaaa acctaaaaat caaccgcgat gttgtcacac aaatcgttga atcaggattt
    16261 aacggtatct ttttagttgc cgctaaccca gtagatattt tgacttactc aacttggaaa
    16321 ttctcaggtt tccctaaaga acgcgtaatc ggttcaggta cctctcttga ctcagctcgt
    16381 ttccgtcaag cacttgcgga attagttgac gttgatgcac gtaacgtcca tgcttacatc
    16441 ttaggtgaac acggagattc agaattccca gtttggtcac atgcaaatgt tgccggcttg
    16501 caaatctatg aatgggtaaa aaacaaccca gaaatcgatg aagaagctat ggttaaccta
    16561 ttctttggcg tacgtgacgc tgcttacaca attatcgaga aaaaaggcgc tactttctat
    16621 ggtatcgcag tagcattagc acgtatcact cgtgccatct tagatgatga aaatgctgtt
    16681 cttcctttat cagtattcat gaatggcgaa tatggattga acgacatcta cattggtgca
    16741 cctgctgtta tcaaccgtca aggtatccaa aaagtaatcg aaattccttt aagtgacagc
    16801 gagcaagacc gtatggctgc ttctgctaag caattaaaag aaattctaga tgaagctttt
    16861 gctaaactag acgctgaata atctttgaac atgacggaaa acatctattc ggtgttttcc
    16921 gtttttttat tttatcaccc ttatggtttc taaatttttt cataaagtag agataacctt
    16981 cgtcttttcc tctaaattat gctatcatga gaccgttcca ccctaaactt ttacttaagg
    17041 agttgtcgat atgacaagat cttcgcatcg aaaaaaatcg aaacatgttg ctttgctttc
    17101 agttcttggt gttctcttag tgctgatcag cttttatacc tatcgcagta catactacac
    17161 aaagcatttt ttgccgaata cagaaataaa tggaataaat gtcagcaatc taacagtcga
    17221 aaaagcaaat gaaaaattaa aagaagctta ttctgataaa aaactggcta ttaaagaaga
    17281 tggaaaagtc tggcaggaag taccaaaatc cgagctcggc tacaaagatg atttcacttc
    17341 ggagctttct ccgatcctaa atgaacaaaa cggatggact tggggaatga cttatgtctc
    17401 agcggcagaa aaacaagaaa tagatcctgt cagtcaaaac caccaaaaac tagacactac
    17461 cgttcagaca ttgacaacta agctgactga tttgaacaaa gaccggacac ctactactga
    17521 tgcaacgatc gaaaaagcag gtgactcttt cgttatcaag cctgaagtca atggaaatac
    17581 gatcgacgtc gatgctgcgg tcaaacaatt aaaaagtgcg gtaaactctg gtaaagatac
    17641 aattgaattg actgaattca aagaaaaacc aaaagtaaca tctgaagaca gctcactgaa
    17701 agaacaactc gcatccatga atgctatcgc aaatgtaaaa gctacttaca gtataaacgg
    17761 tgagactttc cagatcccat caagtgatat tatgagttgg ctgacctaca atgatggaaa
    17821 agtcgattta gatacagaac aagtacgtca atatgtaaca gatttaggca caaagtataa
    17881 cacaagtacg aatgacacaa aatttaaaag tacaaaaaga ggagaagtta cggtcccagt
    17941 tggcacttac agttggacga tccaaacaga cagtgagaca gaagcattga aaaaagcgat
    18001 tctggcaggc caagatttta ctcgttcacc cattgtgcaa ggtggcacaa ccgctgatca
    18061 tccattgatc gaagatacgt atatcgaagt tgatctggag aaccagcata tgtggtatta
    18121 caaagacgga aaagtggccc ttgaaacaga tatcgtttcc ggaaagccaa ctacacctac
    18181 acctgctgga gtcttctatg tttggaataa agaagaagat gcaactttaa aaggaacaaa
    18241 tgacgatgga acaccttacg agagtccggt aaactactgg atgccgattg actggacagg
    18301 tgttggtatc cacgattcag actggcaacc tgaatacggt ggagacttat ggaaaacccg
    18361 cggttcacac ggctgcatca acaccccacc aagtgtaatg aaggaattat tcgggatggt
    18421 cgaaaaagga acgcctgtat tggtcttcta acaaaaataa tatataaaaa gaaagcaccc
    18481 gtacgattgg tacaggtgct ttctttttat tatctaacaa tgtgctactt acatttcagc
    18541 agcagtaaag acttctgaaa catcatcatc gtcttctagc ttatctacta gacgttccaa
    18601 ttgctctttt tgttcctcat ttaaatcaat cgtcgtttgt ggaatcatcg tcaattctgc
    18661 ttgcgccaaa gtgaactctt tttccaactc atctcgtaca gcagcaaaat cttctggtgc
    18721 agtataaatc tcgaatactt caggagaagt ttgcagatct tctgcccccg cctctaatac
    18781 atcctcaaac atcgtctctt catcaacagt caacccatcg cgttcaatag cgatatatcc
    18841 tttgcggtca aacaagtaac tgactgaacc cgtttctccc agtgatccac cgtttcgagt
    18901 aaaagctact cggacatttg tcgctgtccg attacggtta tctgtcaatg catggactaa
    18961 gattcctact ccacccggac catatccttc atacgtgatt tcatcgtaat tcgtttcatc
    19021 tacggcactc gtagcctttt taatcgcccg ttccacattg tcgttaggca tatttgcagc
    19081 ttttgctttg tccacaacaa gccgcaaagc tggattcata gatggatcag gaccgcctgc
    19141 tttagctgcc atataaattt cacgagaaag tttctgaaag actttccctc gttttgcatc
    19201 ttgggcattt tttcttcctt ggatattatg ccatttacta tgtcctgaca tgatttttcc
    19261 tcccttgttc ttttgagaat acacttctat tctagtacta tttcacaaaa aaacaaagcc
    19321 acagccaatc tataaacgct tcttgaatgc cgcaaaaagc acacataata tcacagcagt
    19381 cagagcaccg atcgaatcca acatgacatc ttggaacata ggtgttcgtc caccggtcat
    19441 catctgatgg aattcgtcca aacctgcgta ccctgttgct gaaagccaag caaggatcgc
    19501 tgtcagccac caaattttta gcttggggaa aacacctaaa aacaagctgc ctcccaaaat
    19561 aaaataggta ccgaaatgtg cgcccttcct taaaaagaac tctaaaaatt tggcgtagcc
    19621 cagatggttg atactcacca tacttccacc ataattaaaa cgtatacccg ctaatgtgtc
    19681 tttaaatggc tgattaggca gccagctttc taatcgcgaa acttgtgatt gctgtccgta
    19741 agtttgagaa gaactgtaaa ataagattat aacgactatc agtgcgatta ctaaataaat
    19801 atttccgttt ttcatttgtt tttttgaaga attcataagt cacctctgta ttttatctta
    19861 gacttttttt gaagaaacaa caatcatttt catagagact tcttccataa aaaagtgcta
    19921 tacttaattt tgtattacaa tatgaaggga gttttttcat gagttattca ttaaattgga
    19981 atctagattc tattttttcc ggaggcagtc attctgatgc tttgaaccaa cggatgaagc
    20041 aattggaaga ccaaatgaac gagtattatc accgcgtaac aaaatggtca cctagttctg
    20101 acaatgcaga gcagttaaac gctattcttc aattgcaaga aacgattacg aatggtttta
    20161 cccaatgcag cagctatatt actgcattgc tttctgccaa tgtcaatgat tcagatgcaa
    20221 aggtcttatc aggcaagctt tacgcaatgc tgcctcgtct gcaatcagcc gaaactgtat
    20281 tgtcaaagaa atttgcagaa atatctgaca atgattggaa tcagatgctt tctcaatctt
    20341 cgtttgaaac aattgctttt cgtttaaacg agattcgtcg tgatggctca caattattat
    20401 cagaagctga agaaaacatt ataaatacgc tttctttaga tggtctaaat gcttggagca
    20461 gtcattatga tacgattgta gccagcattt cgattccctt cgaacaagat ggacaagtag
    20521 tcgaattatc tgctggacaa gccttcaata agatgatggg cgatccagat ccaaaagtca
    20581 gagaaacact tttcgcagca tgggaagaag cctggaaaga aaaggcaccc ctcttcacgg
    20641 atactttgaa tcatttagat ggttttagac tttctgacta tgaacttcat ggtgtcacag
    20701 attttctaca aaaaccatta gagtacaatc ggttgaagaa agaaacattg tctgtcatgt
    20761 gggatacaat ccagaaaaac aaacaacccc ttgttaatta cttgactaga aaagctaatc
    20821 ttttcggtaa agaaaaaatg gaatggcaag atcaagatgc acctattatt ttaggcgatt
    20881 tgaaagaaaa aacctttagt tttgacgaag cagcagcatt tattatcgaa aactttaaca
    20941 aattcagtcc aaaaatggct aaatttgccc aatctgcttt tgaaaagagc tggatcgaag
    21001 cagaagatcg tcctgggaaa cgtcctggtg gttattgtac tgagttacca gaaacaaaag
    21061 aatcaaggat ctttatgacc tacagtaatt ctgttaatga ggttgcgaca cttgctcatg
    21121 aactaggaca tgctttccat agcagcacga tgtgggattt accttcttta aatcgcgaat
    21181 atgccatgaa tgtcgcagaa acagcaagta cattcgcaga actgatcgta gccgatgcta
    21241 cattaaaagt cgcaaaaaca aaagaagaaa aaatcaattt gctagataca aaactgcaaa
    21301 atgctttagc tatgttcatg aatatccatt cccgattcat ttttgaaaat cgattctatg
    21361 aagcacggca agaaggatta gtctcagaag ataagatcac agagatgatg gttgaggcgc
    21421 aaaaagaagg ctatcaagga gctttagcta cttaccatcc atatttctgg gctgcaaaat
    21481 tgcatttctt tattgatgac gtaccgtttt ataacttccc atacacattt ggctacctct
    21541 ttagtttggg catctatgct tacgccaacc aaaagggagc aaattttgaa gaagaatata
    21601 tccatttact acgcgatact gcctcaatga cgacggaaga tcttgcgaag aaacatttga
    21661 atgtcgatct tacccaacca gatttttggc aagcaggtat cgacatggtg actgaagata
    21721 tccaaacgtt catggaattg acagaagaat ttatctgatt tctattttat cacaataaaa
    21781 aaagagttag tccagaatgg gctaactctt tttgattaat cattcttaca tgctgacagc
    21841 aaagtcaggg gcaaaccatt gaactgaacc aacttttacg ctttcgcctg gttgaggagc
    21901 atggatatat tgtcctccgc ctaaagcaat cgctacgtgg taagttccgc cttgtgaccc
    21961 ccagaataac aagtctccag cttttgcttg agaaactgaa atttttgttc cagctgattc
    22021 ttgaggaact gtccaaccac cgatgtcacg accagttact tgcatgtaaa catagcgtgt
    22081 gaaccctgag cagtcaaagc cacttggatc tttaccgccc caaacatatg gagtaccaat
    22141 atatttgtaa gcttctgcta cgattgctgc accattcaca cttccagaag gagctggagc
    22201 aggtgttaca ggttttggtt gttcaggtgt tggtgttggc gttggagccg gagtactact
    22261 tcctgtgccg tttcctgtat caacactttg atctgttgat ggtgttgtag gcgcaggtgt
    22321 tgttgattct tctgttgttg aagattcagg cactgttgtt gattcttctg ttgctgaaga
    22381 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcgctgttg ttgattcttc
    22441 tgttgctgaa gattcaggcg ctgttgattc ttctgttgaa gattcaggtg ttgttgattc
    22501 ttctgttgct gaagattgtg tagctgatga tgattcttca gtcattgaag attgtgtagc
    22561 tgatgattct tctgttgctg agctttgtgc agtagatgaa gcttgagtag cttgtgcttc
    22621 agcctctgct tgttcgcgtg cttctttttc agctttttct tgtgcagctt gttgacgagc
    22681 ttgttctgct agacgttgtt gttcacgaat acgagcttgc tctgcttcag cttctgcttt
    22741 ttgacggttc aagtcagctt tcttgtcttc agcagttgct tgttcagcag ctaatgaagt
    22801 tttcagtacg ttcaaatcag cttgtttaga taaaagatcg cctttttgag attccaaagc
    22861 agcttggttt tcagctaatt cttttagttt agcatcgttt tcagcttttt tgtcttctac
    22921 agctttttta tcttgttttt gttgttccat caagtcgttg tttgctttta ccatcgttgt
    22981 cattgcttga acgcgtccaa tagcatctgc taatgaatca gcattcaata cagcatcgat
    23041 gtagtttgag cttgtgttgc ttacttgtgc ttcgcgtgct tgtttttgga ttgtatcttc
    23101 acgtttttca atacgttctt gtaaatctgc aatgtctttt actaattgtg cagattcttg
    23161 acgcaatgta tcttgttttg ctaataggtc ttgtgcttgt gtgttgattt cagaaacttg
    23221 gctttctaag gcatcgattt gtgattgtgc atctgcttgt tgatttttca agtctgcaat
    23281 cttttgatct tgctgttgta tctgagaatc aaaatcgtcc gccgcggcag cgatcggtga
    23341 tgctacggca gtcaaggtca ttgaacatac cattactgct gatattaaac tctttttcac
    23401 tcttcattcc tccgactggc ttaatttaat aaatatctaa atatatttaa gtctttctta
    23461 acgatataaa aattgtacca tagcagtgtg tcaacgatat aatagttatg ttacaaaaat
    23521 gtttcaaaac aacttttaaa aatgacaaaa ctgttcgttt cagaaaatga tcatgaaaaa
    23581 gccgcgttaa gtctagcatt tcttaagata acaacgattc tttttcgctt tcgacctaaa
    23641 aataaaaaaa gaaattattc atcactgaat aatttcttaa agggaaaaat gaataataca
    23701 aatataatca tgttcaacag cagtgtaggt cctaaaaacc ttgtaataaa atacgtgtta
    23761 tttactactg ctaatttaaa aatcaactgg accaccatcg taaacaattc ataacccgtg
    23821 acaaagatga tcatactgaa aaattcagta aagatgttga catggataac gtctttcatt
    23881 acatacatca accatacaat taaagggaga gctactgcat agataccgat aacgccaata
    23941 tagtaagcgt catagatagc cccgagaaca atcgtggtaa tcagtaaata acgtttttca
    24001 aacgccatac tgcaacataa taatgccaat atcagaaagt gggcatttga catataggtg
    24061 cctttcgacc actcccctag cattcttgtt aaatgaccat ctatcaacat caaaaagaac
    24121 aaaacgattg gcagatagta cttcattgtt tctttcttca acatggacta atcctccgct
    24181 agccgttgga caatcgtcac aactgacacg tcatacattt ctgcataagg tttcacataa
    24241 acttcccgat ccagcccata actatctggt ttcgttttaa taaccgtacc gatcggcaag
    24301 ttagctggag aattccctcc aagaccggat gtctggacaa catccccttc tttgatatcc
    24361 gtatcaccag ttaattgggt caccactaag gcatggagct tttcatcata gtttttaagc
    24421 aaaccaaacg cttcgccatt agccgaagat acccgtactg gaaaatgatt ggagctttca
    24481 ttagaggatg acagtaattc gattttagac gaagccgtat tgacctcgat cactcggcca
    24541 atcaatcctt tttgcgacat gactgccata tttgcttcga taccgtcttt agaacccttg
    24601 tctacgatca gcatgtcctg ccaactgtca ggcgaacgag taatgacatt tgccgttact
    24661 ttttcgtaac tagtcagcgt ctgattcaac tcaagttctt ttttcaacgc ttcgatttct
    24721 ctctcgtaat tcttgttttg ctgtgaaacg tcatcatagc tatcgatttt ttcttttagc
    24781 cgctcatttt cggcataagt tgaaaaaaga ttatggacag aatctactcc atttcgtacc
    24841 caccgtactg gggcagagat tgttttatca accattgcaa cactgtcatt aacgatggat
    24901 tggaagaaat tgggctttcc ttcattcgct cgctgcgcag cggtcacact tagtatcgtc
    24961 accacgatga taacaataac caaggtaata ataatatttt tattaggatt gaacttcttc
    25021 acaaagacac ctcgaattaa ttagactctt gtgttcaatt ttatcactaa atgccgtgaa
    25081 acaaaaggta agttgctcct cttaagcttt tttttagcaa ataatagatt ctgtcatttt
    25141 tagcctgaaa gacaaatttt tttatttgtt tatggatcaa tctttgcttt gaataactgc
    25201 aatcatacca tctgaaaaag aaaattctgc ggtatctgaa agaaattcgt tacttgcata
    25261 agatgtcgga tattctactt ctttattttc caatacatac ttgctgcctt ttaatgtaag
    25321 attcgagacg ggagtcaagc agcaataagc taaatacttc atatctggta tctgtcttac
    25381 tatatgctct ccaggcaaat aataagacaa ataattttga caatctctga taataagctg
    25441 atgggcaaag ggtttgaagc gaggttccat acctaaccag agattggcta aaagatgatc
    25501 caatcttccg cccgtagctc caatcaaagt gacttccgct tgcgggtaac gttcaaatgt
    25561 ttttaagata cctaactgtg tatctgtatc gtctttttct gcaggggaac gggtatactc
    25621 tttggctttt gcaaatactt ccttctgctc ttcgttcgac aatgaatcaa aatcacccac
    25681 tgccagatct actgggtagc ctgcttgaag caggtacagc gcaccacggt ctatcccgac
    25741 ataggcatcg tatttggaca gcagagactg cggccagttt tgcggattac ctccagcagc
    25801 taataaaatt ttcatttagt ctaatgcctc ttttaatcgt tcgatttgtc cgactggatt
    25861 ttcggctcca tagatatatg atcctgcaac gaagacatcc gcccctgcat ctttacagat
    25921 ttttgctgtt tctggaacga ttccgccatc tacttcgatt gcataagtcc aattgttctc
    25981 tctacgtaga tcagcgagtt ccgtaatttt ttctactgtt tcttcaataa agctttgtcc
    26041 gccgaaccca ggattgacag tcatgactag tacttgatca gccaaaggca aaacatgttt
    26101 gatcatggag actggtgttc ctggattgat aactactcca gctttaactc ctaagctttt
    26161 tgtcatttga agtgcccgat gaatatgagg agttgcttcg acgtggacag taatgatatc
    26221 tgctccagct tttgcaaatg ctggaatgta gttttctgga tcaacgatca tcagatggac
    26281 gtctaacggt aatttagtaa caggacggat tgcctgaaca atatttggcc ctaatgtgat
    26341 atttgggaca aatcggccat ccattacatc tacgtggatg taatctgcgc ctcctttttc
    26401 cactaactca atgtctcttt gtaaattggc aaaatctgca ctcaaaatgg atggtgctat
    26461 cttcattctt gtttcctcct attttcgttt accttctttt tttgcataca ttggttttct
    26521 tttttcgatt tcttgtaaga attgcaaata attgtcgtaa cgtgtctgtg cgataccacc
    26581 tgtttctact ctatgtttta cttcgcagcc aggttcttta gcatgcatgc actctctaaa
    26641 tttgcaatgg acagaagctt ctacaaattc aggaaattgt ctcggcagtt ctcctgcttc
    26701 aattgtcaaa aagtcaatcg agctaaatcc tggtgtatct gctactaacc cgccatagat
    26761 aggaatcagt tccacatgac gtgttgtatg ccgtcctctt ccaagtgcat cagaaatctc
    26821 tcctgttgct aaattcagtt ccggtgatat ttgattcagt agcgtcgatt ttcctgctcc
    26881 agactgaccc ataaagaccg atagccgttc tgggaagtaa cggatcagtt ctgtcgtatc
    26941 acccgtatga ttgggtacaa tcaccggata gcctatttta gtataggttt gcttgatctc
    27001 ttcgattttt tctgggtcgt ctgacaagtc ggtctttgtc aaaaaaataa tcggttcgat
    27061 cgactcgtat tccaaggtaa ctagaaagcg gtcaagtaga ttataagaaa atgcaggctc
    27121 tacgatactt gtgacaatga ttccaagatc aacatttgtg actggtgggc gaactaattg
    27181 attttttctc ggcaagattt ccagaagata gccgtctgtt tgattttcac tctcaaagat
    27241 cacctgatct ccgacaagcg gcgtgatttt ccgattccgg aaatttcctc ttcctcttgt
    27301 ttgataggtc tctccgtttg cgtatacata gtaaaaaccg ctgattgctt ttctgatttg
    27361 tcctttgata agtgccacct ccgtttttgt ttattttacc atacgaagag gaaagtaggt
    27421 gttattccat gcaaacttct caaagtatat ggcttgaaaa ttgatcaaaa gagatagaaa
    27481 cacaaaaaag agaatgcaac aaatcaatgt cgcattccct tctgatatat tttattcagc
    27541 acttattttg aactttctga ggtgctagct gatgaacttg tggagctgga agattcttct
    27601 tttgaagagt tgcttgtgct actggagcta cttgagctgc tagaactgtc tgaagagtct
    27661 ttttcagaac tagaagacgc tggatctggt cctttagagt aaattacgtt cacaaccatt
    27721 cctttggtaa ttgtcgttcc tgcccctggt actgtacgaa tcactttatc tttatccacc
    27781 gtgtttgaat attcggaagt ctcatgcccg atatattctg caccgacact agctaaataa
    27841 ctttgtgctt cgctttttgt atagccggag atatcattca atttaggctc tgttccttgg
    27901 cttacgacaa aattgatgta agtttcttct gctacaactt cacccgaggc tggatcctga
    27961 ctgatgatcg aacctgatgg tacagtgtcg ctatagtcat aagtagcact aatattattg
    28021 atattgaatc cttgtgtaac aagccaatta cgaacagttt cgtagttttc tcctacatga
    28081 ctactcaaag tcactgtttc tggtcctttg ctgactgtga aagtaatcgt gtctgtttta
    28141 ggatcgactt ctgtatcttc tgatggagat tgcgaaatga tcattccgct ttctacctct
    28201 gaactgaatt cctcttcttt ttgaatcaag tcagcagaaa accctaattc tttcaaactt
    28261 gcttcggcat cttcataact tttaccactg taatcatcta atttgatttt tttcgtgccg
    28321 ctactaatat acagagtgac ttcgcgtttt tgcttgactg tcgttcccgc tgccgggtct
    28381 gtcttcacta cattaccttc ttcgattttg tcatctgcaa tttcttctgt ttttgttgct
    28441 acttctaatt tcgcttttgc gagtgtttct ctagcagaag cttcagaaag atcagaaaca
    28501 tcaggaacaa caacttctcc tcgcccgcca gaagcaaaga atacagctgt tccgattcct
    28561 aaaacagcaa gaatagctaa taggatcagc caccattttt tctgtccttt ctttttagga
    28621 tcaggcagaa cttcttcctc ctctggtaag gtttcgtttt ctggcttgtc ttttggcaga
    28681 ggcatagatt tgaatgaatc aggcattggt gcatcttccg taaggggtgt gataactttt
    28741 gtttcattat ccatcacatg aggctgccat ttttcttcgt ttgcacgagc tggtgataat
    28801 actgtagaaa gatcatcaga catttcctcg gctgacttat aacggtctgc aggttcttta
    28861 gccgttgccc gtaaaatcac gttttccagt gcttgtggca catttggatc aagtgctttt
    28921 atagatggaa gatcatcttg aaaatgtttt aaagcaattg ttacagcaga ttcaccatca
    28981 aacggtacgc tacccgtcaa catctcataa aggatgatcc ctaaagcata aatatctgac
    29041 tgcttcgttg ccatacttcc tctggcctgc tcaggggaca gataatgaac agatcctagc
    29101 atcgtattcg tctgcgtgat cgatgtttca gataaagcga tagcaatccc gaaatccgtg
    29161 atttttacaa caccttcatt atcgatcagt acgttttggg gtttcaaatc tcggtggatg
    29221 atttgatggt tatgagctaa agaaatagca gaaaggatct gctgcataat atttactgct
    29281 gtttcataag gaacaggata atgtgtttgg atatatcgtt tcaagtccat tcctttgacg
    29341 tattccatca ccagatactg catgttgtct tcttcaccaa catcgtaaac actaacaatg
    29401 tttggatgaa cgagttctgt tgctgctaaa gcttctctct gaaatcgtcg aatcgcagtc
    29461 tggtcatttt gaaagtcaaa tcgtaagact ttaactgcta catcacgatc caagattaaa
    29521 tcgtgcgcca aaaatacatt tgccatacca ccgctaccga tatttccagt gatttgataa
    29581 cggccattta attttttgcc caactcgatc atacactgtc ctccttatat tcgataagaa
    29641 gaacggtgat attatccgct ccgcctgctt cattggcacg atcaatcagc tcagttactt
    29701 tatgagacaa tgggccttct tgattgatga tcgttcctat ttcttcttca gacagcatgt
    29761 tcgtcaagcc atctgaacat aacagcagtc gatcttttag ttgccaaaga tgagtagaaa
    29821 catctacttc gactgttcca ggcatgccga cagaacgtgt taaaatattt ttccttggat
    29881 ggttcactgc catttcttcg ctgatttctc ctgatttgac tagttcattg actaaagaat
    29941 gatcctccgt caattgcatg attttatctt cacgaatcaa ataagctctg ctatccccaa
    30001 cattggcaat cgtgaaccag tcatctgaca gagcggccgc tacgattgtt gttcccatac
    30061 cgttatattc cggctgttct tgtccacgct gataaatcag catattttct tcttgaatcg
    30121 attgaatgaa ccattgggcg attttttcat cgtcaacagc ttcttgtttt tcccaagctt
    30181 cgcctagatt cgttaccgcc atctgactgg caatgtctcc ggcacgatga ccacccatcc
    30241 cgtctgctaa tacagcaagc ttgagacctg aacggctggt aaatacactg gcatagtctt
    30301 gatttgtgtt acgtcgtctt cctacatctg attgatattc aatctgcatt ttttcacctc
    30361 attacttttt gcgcaaacaa caaatgaaaa atccatctgt gtaaaactga tgcggataca
    30421 aagtcaacat tttctcttcg attgatgatt gtagcatagg attggtcaaa acatcaatcc
    30481 tctcaaaatc agggtgtctt tccaagaaag cagaaacaac gtcttggttt tcttctttta
    30541 agatcgtaca agtgctataa gtcagaatac cggaagactt taaagttggt gcgcagcttt
    30601 ctaaaatttc caattggatt tttggtaaat tcgctaattc atccggctgt tttttataac
    30661 gaatatctgg ttttcgccga agcagcccaa gacctgaaca aggcgcgtct actaaaatcc
    30721 gatcaaactg ctctgcttcg aactgtttac tgacttctct agcatccatc ttttgagcgt
    30781 agacagcaga agagacacct agacgtgctg cattatcttc aatgagtttg actttgtgtt
    30841 cgtgtacatc taaagcgacc acttctccac cgcatgacgg atctaaaaaa gaagcaatat
    30901 gcgtcgtctt acctccgggt gctgcacagg catctaagac atgatgttca ggctcgattt
    30961 gcatagacgg cgctacaagc atcgaacttt catcttggat cgtcatgacg ccatcgtgga
    31021 acaatgagct agaagctaaa tgcccttttt tcgctactat accgtatgga ctgacttggc
    31081 ttttttcagc tgtgatctct tcttcttgca aaacagtgat ggcctgatct ctggaaagtc
    31141 ggcgtgtatc tactcgggca ctagcatggc taggctgata tagcgataaa ccgagctttt
    31201 cagtttcttc gtatccgatt tgatccacca gtcgtttcgt catccataga ggcaggctga
    31261 ttttgacaga aagtctttcg ataggatcag caatgccttg cagatctggt gctccttgac
    31321 gctgataatt cctcaagaca ccatttacaa atttccctgt cccaggattt ccttttactt
    31381 ttgcgatttc gaccgcctcg tttaaaatag catgtgcagg gactttatct aaaaattcta
    31441 attggtatac agaaagataa agaagcatct tgacccagtc atccactttt tttgctttag
    31501 cgatcaatgg tgcaacgtaa aattccaata gtcgctgatg gctaatcgta ccatagatca
    31561 attctgtaaa taaacccaca tctttttgat ttagctcgct ttgtttgatc atctcattca
    31621 acaaaagatt cgagtaggcg ccacccttgt tcactcgctc taatgtcagt aatgccatat
    31681 atcgtactga ttttttcatt tttttaggga tttttttcat tatttcacct gctgaccaat
    31741 ctgaacttgc tgaccgcttc cgttaaggaa atcatgtacg gcctgttttc ctttaccagc
    31801 tggctgtaat tcattgatgg ctaagacggt ctgtttaccg caagcaatcc atagattttt
    31861 tttgtctttc cggatgatcg taccaggtgc tttgtctgta gtttctgcca atacttcaac
    31921 cgataataat ttccagcgta tgccctcata ggtcgtgaat gcaattggcc aaggacgcat
    31981 tccgcgtact tggttgtcaa tttcttctgc agttttatgc caatcgattg cttcttgttc
    32041 ccgtgtgatg tttggcgaaa aagttgcttc tgactcgtct tgaggtactg gtttttgtcc
    32101 atccaaaata ttgggcaatg tttctagcaa tagctttctt cctaaaaggc taagcttttc
    32161 aaacatcgtc cctacatcat cttgtttagt gattggtatg ctttcttgcg catagattcc
    32221 gcctgcatcc atttttttga tcatttccat gatcgttaca ccagtttctt tctccccatt
    32281 catgatggca taatgaacag gcgcacctcc ccgatattta ggaagtaaag aagcatggac
    32341 attgattgcc cctaattttg gtacttgcaa taacttttca ggcaagaatt ggccaaatgc
    32401 cgcagtgacg atcacatcag gcaccaattc aatgatttct tccatttctg gcgaaccgga
    32461 gattttctct ggctgcagca cacggatacc gtgcttcaga gccgcttttt ttaccggtgt
    32521 cggcgtaatt actcgtttcc gcccaactgg acggtcgggc tgtgttacca ctgcctggat
    32581 ctcgtaacct gattctatca gcccttcaag aatcggcaca gaaaaagcag gtgtgcccat
    32641 aaatactagc ttagtcatca agatgttcct ccatatattc ttcaagttct tcttccggga
    32701 tctgctgtat cattttctca atgaacaaga taccgtctaa gtgatcgatt tcatgctgga
    32761 aggcacgggc taaatagcca aaagccgtca cttctatctc ttctccgtct cgatcataat
    32821 aacgcacggt cacttcatct gctcgcttga ccgttccata gacatgcgga atactgagac
    32881 aaccttctac gtcaaggctt tcaccttttg cttcgatgat ttctgggtta atcagttcaa
    32941 atttctcgcc ttcatctact tcgatcacag caattctctt gttttgtcct acttgaggag
    33001 cagcgatccc tattccgtca ttcgcaatca ttgtctcata taaattgtct aataaagcga
    33061 ttgtctcgtc cgtgattaca tcgattggct gagcagttct ttttaattta tcattagggt
    33121 ggatcaatat aggatagcgc ataatttggc cctttcttaa ataaagttta atggttcgtt
    33181 gtcaattgcc acaaaaagac cttgtcgctg ttctttctgg cttccattca aaatttcatc
    33241 caaaacatga ggaagattcg gttcatgttt atatttgatg attagttgat aataatatcg
    33301 gtttttcact ctcaaaatca tgctgggcgt tggccctaat agcaagcttt gagggcttaa
    33361 cacttctttt agctgattgg caatctgaaa gattttcttt gccgctactt gttcttcagg
    33421 atggctggcg gttattttca cagtaaagta ataaggagga tagcctccac gatgccgtac
    33481 atgcatttcc tgctgataaa actgctcata attttgtttt ttagccaatt ctatggcgta
    33541 atgttgagga ttgaatgttt ggatcacgac ttcgcctgct ttttccgctc gccctgctcg
    33601 tcctgaaact tgggtaagca attggaatgt atgctcacta gaacgaaaat ccggtaaatt
    33661 cagggaggta tcagcattca acaccccaac taatgtcact tctggaaagt ccaaaccttt
    33721 agcaatcatt tgtgtcccta ataatatatc tgcttctttt gcaccgaatt tttgtaaaat
    33781 ctgttcgtgt gccccttttc ttcgagtggt atctacatcc atacgcaaaa tcctagcttg
    33841 cggataaagt tctcggagtt cctcttctac tttttgagta cctgttccat agtagcggat
    33901 tttattgccg ccacaattag gacagcgatt gggaataggt tcttcatgtc cgcaataatg
    33961 gcagcgcatt gaacgtgtat ccatatgcag tgtaagagag atatcgcaat taggacatgg
    34021 aagaacaaat ccacagtccc tacacatcac aaaagacgaa tatcctcgac gattgagcag
    34081 taggacagtt tgttcttttt tgtctaatcg attttgtatt ttttcctgca aattagcaga
    34141 aaaagtagag gtccgatgat tctgaaactc ttcacgcata tctacgatct caatagctgg
    34201 aagctgtgca gctgctttgg ctcggtggtt taactgcaat aactgataaa cgcctttttg
    34261 agctcgtgct cttgattcta aagagggcgt cgcgcttcct agaactattg ggcaatgatg
    34321 atatttactg cgccaaattg ctagatctct cgcatgataa cgcggtgtct catcttgttt
    34381 gtaacttgat tcatgttctt catcgataat gatcagcccg atatttttca gcggggcaaa
    34441 aatagcagat cgtgcgccta ctactacttg cgcttcttcc cgctcaatct tgcgccattc
    34501 atcatatttt tcaccttggg aaagtccgct atgtaagacc gcaactgatt ctccgaagcg
    34561 tcctttgaat cgctcgacca tttgcggagt caatgcgatt tcaggcacta acataatagc
    34621 cgttttattt tctgacaaaa catcagcgat tgcctgaaga tatacttctg ttttcccgct
    34681 gccagtgatt ccctccagca aaaagacctg atctttttgc tgctgacctg ctgtgatgat
    34741 ttgttcgaca gcattttttt gttctgcatt cagttccaat gccgtcgttt ggtcaaatac
    34801 tcggtcttta taagggtcgc gataacgttc tgattctata aactccagcc agcccttttc
    34861 ttttccttga ttcaagacag cagtactgat tcctttattt ttgaaataag caattggttc
    34921 ttcttggctc agttcagata aacacaaaag aagttctttt tgtttcttgg cattttgccg
    34981 taattttgcc cattcttctt cgatttgctt ttcagttaac aaagaacgga ccaaacgaat
    35041 cgtttttact ttatttcgtg tatggacttc atatttgata tctactaatt gctcttggcg
    35101 ccagcgaatc aattgagaaa ggctgccttc ttcttctgct tccttccagg aaatcacttc
    35161 tcgctgatca aacaatacct gaacttctgg tgtgtctgcc aaaggataga tcaatttatc
    35221 atattctgct ttcatcacac tcggaagcat cgtttgtaga caagtgattt tgaatgcgta
    35281 agtaattttt ttcatataat cagctaatga aagtaattct tcattgacca ccggagcaag
    35341 gtctagcaaa cgaataactg ccttcaaaga tggattagct gattcttctg atttttggat
    35401 agccataaca aatccttgga catgacgatt gccattacca aaagggactt ctactcgcat
    35461 cccgacttgc aaagctgttt ccatttcaga gggaaccaaa taagtgaatg gctgatcggt
    35521 ctgcatagta ggtacgtcca caatgacttc agctgttaat gtcatggttc gtttcctcct
    35581 ttttttgtct tttcttatca agcgacaaaa agttccttgc ctattttact agagatcgat
    35641 ggatttgtct tatcttctgc caaatcctaa caaaaaatta acagcagata agaaaaaaaa
    35701 gaactgtgtc aaaaagttca gacacagcct tttctaccag acaataagtg gcgaatgttt
    35761 gaaaaggaaa cagctgggtt tgcttttctt tttagatgtt cgctctattt ttctttatta
    35821 cattttttgc tcttcacgga tacgtgattc caattcgtgt tgttcacgct ctttttgtgc
    35881 ttgacgttcc tcttcttcca tcttcaaacg ttcacgtttt aattcaggat gtggatcatt
    35941 gactacattt cctgcatcga tttcttctaa agcttgaccg acgcttttta ctgaatcaaa
    36001 agaatctaga gtaggctgtg cacttgcatc caattcatgc gcgcgtttac ttgctaaaat
    36061 cactagagaa tattttgaat ttacacgatc taatagtgag tcaattgaag gttttaacat
    36121 cataagacta catctccttt aacattttaa tatatttacc gattacgcga tctactcgaa
    36181 aatgttcact ggcaataatg tttttgattc gttcaactgc tagcggcact tcatcattta
    36241 caacagcata gtcgtaaaga gccatcattt cgatttcttc ttttgcaact ttcattcgtt
    36301 tttcgattac ttcatctgca tctgttcctc ggcctacgat ccgtgatttt aattccgcta
    36361 aatctggcgg agtcaaaaag atgaatacac catcgggcac tttttctttg acttgttttg
    36421 ctccttggac ttcaatctcc aagaaaacat cttttccttc atccaatgtc ttgttgacat
    36481 atgacaaagg agttccataa taattcccga catattctgc gtattccagc atctctccag
    36541 cttcgatcat tgattcaaac tcttctttgc ttcggaagaa ataatcaacg ccttcgacct
    36601 ccccttcacg cattttacgg gtagtcattg agatcgaata ctgaaaatca ttatcctcac
    36661 tctcaaaaat tgcttttcgt actgtgcctt ttcctacacc ggatggacca gacaacacga
    36721 ttaataatcc acgctctgac atgacgacgt cctttcaact agtctttttg tacttatcgt
    36781 ttattttgca ctttttttct gcaactttca aggttatctt taattatagc tagaaattgg
    36841 taaaaaagct accctgtacc aagaggtcgt aaaaaagctg tcctgcatca agtaataaga
    36901 acagccaaac ataaacagct tctcatgttt ttcgtttggt tggggttatt atcgcagatg
    36961 caagcttttg aacgccgtgt ataagaggtc gtgaagaagc cgattagttt cgagtatgaa
    37021 gaaaaatttt gtgaaaatag tttctcacat ttttgcataa atttggctta ataccgagaa
    37081 aatggttttt gaacatcact tattcaaaat aaaaaaagat tgtgacacga attttgtcac
    37141 aacctttaaa tgtattccta gagcaaagaa gctaagcgaa gaaatccaat tctgtttatt
    37201 tattgtattt ctttgttcag catccttgct aaaagcccat attggacaaa gtattcacta
    37261 cacccatgat ctcatctttt cgagaacgtg ctttttctgt cggatcttct acctcttctg
    37321 tgtcaattcg aacaataaat ttccgattca tcgtcacgta agcaccgtcg ttgatcaaaa
    37381 taaacagttc gttctcatta tagtctgcac aggcatcttt ccatacgtca aagccgtttt
    37441 tttcagaagg gatatcccgt ttaaccacag tttttccact taattcgtgg aacgttacgt
    37501 cataatattt cattatctct acctctttcg tcattcaata ttttgtactt gttctctgat
    37561 tttttctaag atcgtcttag actggacgac ttgattttta atttcgattg catttgattt
    37621 ggaaccgatc gtgttgattt cccgattcat ttcttggatc aggaaatcta attcccgacc
    37681 tacaggacat tgtgcttcga taagttcatc tagtttttgt acatggatcg ccagacgatc
    37741 cagttcctcg tgaatatctc cgcgttccaa caagatggct agctccgtca acaaccgttg
    37801 ctcatcgact ttcgctccaa gaaattcctc cagctttttt tgatacctta tttgaaattc
    37861 cttttcatag atttctacaa aactatcgag tttttttagt acttctttga attcttcagt
    37921 attctttttc aacactaaag ctaaagcttg accttctttt tctcgactcg cctcaataga
    37981 atcaagtgcg cttttcaatg tatctagagc taactgtgcc aattcttcca tgctctcttc
    38041 cggtttttct tctaccgtta cgaagttttc gtccagcacg aagcgttccg ccatccgact
    38101 aattgacact tgattttgac taccgtatcg ttgttgaatt ccgtctgtca attgagtgat
    38161 aagtgaatca atcaattccc agttgatgac gatctgtttt tcgtttttgc caatataagc
    38221 tagattcaca aatacttcga ttcgaccgcg gcttaactgc tgtttaataa gctgacgaaa
    38281 atcgttttca acaaagttca ggattttagg acttcgtatt tgaacatcta gaaaacgctg
    38341 gttgacactt tttatttcaa tatctaactg atacgctttt gtttcgcgga tggctttgcc
    38401 aaaaccagtc atacttttca ttcgacaggg tccttcctca ttacatattt tctattgctt
    38461 tttgcagttg ttcaaactct tcgttcgtca atgtcaggcc tttccccatt ttttcatggt
    38521 ctggcgccca atctcgaaga tcgaattttg gcgggcgacc attccagctg actaggttca
    38581 gttctttacg ccaccccttg ttgttttctg acaatatagc gatttcttct acgatttcat
    38641 atgaaaattc ttgtgccatg gttgttcctc cttgagataa tataaatata ggatcagtaa
    38701 tgtgtcaact ggttgcttaa gcaattcatg ctgcaaacga tccttgcgtt ttccttgtag
    38761 cagataatca aaataaacag ttttcgtgcg ctcattttgt attttttgct ggtattttcg
    38821 ataccttcgc cattcttcag tacttaattg accaatttgt gccaataaat catccggcat
    38881 actttttata tcttgttggc agatcatttg aatcatcatg tctacttgat agatttcatt
    38941 gggcagtaaa aaatgttttt ttgctaaaag ttctagcatc gccaatccgc atgtctctgg
    39001 tacgaccctg ttcttatata aattacgcag tttttgccaa aattttatgc ttttgaaaaa
    39061 agataattct aactgaattt cttttgttaa gtaagacaaa aatcctcgcc agtatgttct
    39121 tgcaggttta acagaatgaa atgtatacca gttcccatag taatagccta atcgtttttt
    39181 catttccaga tagcctaatt gtaaatttaa ttggttcctt tggctatcaa aaagcagaaa
    39241 gctgcctagt gtccacaatg tttgacattt ccaatggata aaaatgtctg gcatacgaat
    39301 ttttttcgct gggcctggcc cttgcacatc tacgacaaat gcctctgttg ctcctttgtt
    39361 aatcgcaata tcaataggta ttttgttgcg atacccaccg tctgcatatt tattttttcc
    39421 gatctttcga taagccatag cgggataaaa tgaagcagag gcgagtatcc aatctggtat
    39481 ttcttctgtt tttgtctgtt ggatatcagt cactacttcc gctagttctg gcagtttagt
    39541 agacaccgta tataaacgta ttttgggatt atgtttgagt aaggacaaat ccaaattgtc
    39601 tttgaccatc ttttccaatg gagcagaaga aaccccgcct tcaattagtg ctgttttcgt
    39661 catttggcgt ctttctcgat agaagcgttc acgaaggtct tcaactgcag ccatttctgg
    39721 taacgcaagc acttgtcttg tcgacagctt tttccataaa ttcacagctt ttttcatatc
    39781 tccttgtaaa atcaatgcgc cgttcaacgc acctaccgag gtacctgtga taatctcaaa
    39841 gttgatatca tgttccttca gcgcctgcca cacaccaatc tgataagcac cgtgcgctcc
    39901 tcctccacct aaaacaagtg ctgtatgata gaccagcttt ttatttaatt gtgtggttcc
    39961 ttgatagccg tttttatgaa aaatacgcaa ccattcttct gatagaggag attgaaataa
    40021 aaaacaacag ttttctttaa taaaaaaacg agcgcaagct tccatatacc gaaaaaattt
    40081 tttccattca aaagtttcac cttcaatcaa cagattatta aaaataacat ctcctctact
    40141 tttagcaata gtaaaataga cggtatattt tttcgatact gctttaaaag cacattgctt
    40201 ttttgcagaa cgccaaaaag cgtctctact ttcttgatga ctttgaaaaa atggaagggg
    40261 ttgttttgct tgctggatag gcgaatacag cgacattttc tgtgaaaagt aaactttttt
    40321 tatctccatc gcgctctcct ttttcttcaa gtataccagt acgtcataaa aaggtcatga
    40381 gtctcgtatt cgactttgta gattccataa gaaaacaatt cataaaacct cctttaaata
    40441 aaaaaataca aaaatcacaa aaattaattg aaaatgagag tgttttcaat gaaaacgtga
    40501 ttttgtaatg gaattttaaa ataaaagaaa caagcttttt taatgcaaat gttgtaaaat
    40561 aaaagagatt aagaggaaat aagaggagga acatgatgac tgagtcagtt tatgtacata
    40621 ttgataccac aagtaatgct gttttaacaa aagggctgac tgctactgac tttgcaaaca
    40681 gtatcgtgca ttttcctcaa aacttgctct tgcttgatcc atctgcttct gctggagaat
    40741 atgaatccca tacagggctg aaagtaatcc gtggtacaga aaatattcag cgtttctttt
    40801 cctcttctcg taacaggcgt ggattcgatg aattgaagtg gatcgacttt actgatttaa
    40861 cgatgctgaa agaattgaca cctttagaaa tttcagaatt attatatttt ggtcatatga
    40921 aaacacatct tcattcgccg tttttttata aactacagaa taattttgta tacttcgatc
    40981 ttaatgatca gctgaatcgg atttattatc gctatttaga tgaattttat aggatttttg
    41041 ctagtaaatt aagttcgatc ttgtcagata agatcaatgt aaaaaaatct tttttcaaaa
    41101 aagaaacacc tgttgaaaaa atcagtgtgg aattattgaa agaaatgcgt aatttgatgc
    41161 aggaagggat cattttttct tttgatcaag ttggtttgat cgatggtaaa tatcgtatcc
    41221 caatctatgt gattgaagat tatatttgga aattaaaagg cacccggtat cgagaagagg
    41281 aaatcatcgc tactttaatc tactctgtca ccgatcgaca ctggcaattg gtagaagatg
    41341 ccgatctttc ttatctgcca ttgaagtaga tctatttctt atcaaaaaat aaaaaggaaa
    41401 caagaaacta ggacatgatt ctgtctcaag tttcttgctt cttttttatt tacagctcct
    41461 gtcgtttatc tggcacaaaa atcgaaggag tcgtttgttg gatccctaat aaaacgatga
    41521 tcgttacaat agctgtactc aacccgctgg caccattcat tacgaaagaa aagagccaag
    41581 gattcatccc ccatagtgca tacgctcccc agaaaaccac tcctgcaata aaatgccaaa
    41641 aatatctgga aagtgcgcca atcaatgcac caaacacgat gctttttcta atttgtttcg
    41701 tattatcgtc tacatagcct ttttggacat ttgaagccat gagccctgct gcgcctgcaa
    41761 aagtataggc aatcgggtac tcaatcaaca cttgaacgac acttaaataa taaacttgtc
    41821 ccaacggaaa atgtaggatg ccccaaatga aacctgccag catccctgcc tttgtccctc
    41881 ttcttaacgc aaaaagagtc aatggaatct gccctaatga aatagaaaaa ctgctgccga
    41941 tctggatcgg aatcaacgac aacaccatcg ctaacgctgc aacaatcgtt ccttctaccc
    42001 aaactctatt ttttcccata aaaaaacttc ctcctttgaa taaaaaagtc acaaaggagg
    42061 aagcagcttt cgaaaatagt caaacagctg tttattcaca attcctacgc tcgcataacc
    42121 gatacaggta cgaagggttt agaaatagat tcaatctcag cccaattgga ctcccctttg
    42181 tgagtttatt tattatttat tttttgtttc aaacaatgga ctaactggtt tgttttcatg
    42241 gatacgtttg attgcatctc ccattagtcc gccaacactt acttcatcga ttttgtcgat
    42301 tttacgatct tctggaagat agatcgagtc tgtaacaact agacgctcga tagctgaatc
    42361 ttctattctt tgtaaagcag ggccggataa tactggatgt gtacatgaag catacacact
    42421 agttgcacca gcttctttca aagcattggc agccaatgtg atcgtacctg ctgtatcgat
    42481 catatcatcg atcagtacac aagttttgcc tttgacttgt ccaatgatat tcattacttc
    42541 tgcaacattt gcttttggac ggcgtttgtc tatgatcgca atcggagatt tcaaaaattc
    42601 cgctaattta cgtgcccgtg tgacaccacc atggtctggt gaaacaacga caacatcatc
    42661 gcctttgatt cctttttcta agaaataatt ggcaataagt ggcgcaccca tcaaatgatc
    42721 gactggaata tcaaagaaac cttggatttg gactgcatga aggtccaaag tcagcattct
    42781 tgttgcacca gctttttgaa tcatgtttgc tactaatttc gctgtgattg gttcccgtgc
    42841 acgtgcttta cggtcttgac gcgcatagcc ataataaggc atgactacgt tgattgtttt
    42901 tgcacttgct cgtttcagtg cgtcaatcat gatcagcaac tccatcaagt tatcattgac
    42961 tgggctgctc gttgattgaa taacatagac atgcgatcca cgaatacttt cttcaatgtt
    43021 tacttgaatt tctccatcac taaattgagt aacagatgat tttcctaact cgacgccgac
    43081 tgctgctgca attttctctg ctaatgggcg attggaattt aacgcaaaaa tttttaatct
    43141 tgggtcaaag taatgttttg acatggggac ctccactttc tttttcacaa ctctagaatt
    43201 ctacctaata aatagtagtc atatttttta aataaatcaa gtgattttgc aaaagtctta
    43261 gtttagataa gggagttttt ttgcatatcc ttctttattg acttgtcttg ctctcgcaat
    43321 tgccagcgca tattctggaa tattgtctgt aattgttgac ccggcagcaa tcgaactgtt
    43381 tttagctacc tcgacaggtc cgatgatatt cgtgctagaa ccaataaagc tgtggtcgcc
    43441 gacagtcgta tgatgtttgt tctttccatc atagttgacg aagacaacac cacatccgac
    43501 attgatttct tctcccagcg tagcatcacc aacataagtc aagtgaccga ctttagttcc
    43561 tttgccgatt tgagcatttt tcacttccac aaagtttccg atatggacgt tttcgccaat
    43621 ttcagctttt ggtcgtaaat gtgcataagg tcccacatct gcatgtttct tgacatggct
    43681 gctttcaatg actgagtttt caatgacgac gtgatcctca atcctactgt ctacgatttt
    43741 tgaatgtgac ccgatgacac aatcagaacc aatgactgta tttccttgga tttgtacacc
    43801 tgcttcgatc aatgtgtctg gaccgatttc tacgcctgca tcgatgtatg tcgttgctga
    43861 atcgacaaag cttacgccat tgaccatatg catctggtta attcgctttc tcatgatctc
    43921 atttgcttta gctaacgcga tccgatcatt gactcccatt gattcttcaa aatcatccgt
    43981 ttgataagca gcaactgtat ggccttcttc ttttaagatt tcgatgatat ctgttagata
    44041 gtattcacct tgagcattgt ttgttccaac tttgcttaac gcatcgaaca aagcttcgtt
    44101 gtcaaaacag taagttcctg tattgatttc ttgtacaaga gcttcttctg gtgttgcatc
    44161 tttttgttcc acgatttttt ctacgatccc aatatggtca cggatgattc gtccatatcc
    44221 tgttgggttt tctgcttgtg ccgtcaagat cgttgcactt gcattttttc cttggtgata
    44281 ttcaaaaaga ttgttcagcg tttcagtagt caataatggt gtatcgccac tgataactaa
    44341 cgttgttcct ttttttcctt ccaagaaaga agcagcttgc aaaacagcat gtcctgttcc
    44401 caattgttct gcttgtaacg catatttact gcgttctcct agttgtgctt taacttgttc
    44461 tgctccgtgt ccaacgatcg taatcacttc atctggtttc gtttcactga cccgattaat
    44521 gatatgttct accataggtt taccagaaac gggatgtaaa actttatata attttgactt
    44581 catgcgggta cctttccctg ccgccaaaat aattgcataa cgtgcgtcca actgcgtcac
    44641 tcctaaatat agtttgctga tttcagttta tcccagtata cccatttttt caacaaaaca
    44701 agtgattttc ttttatccca gcgttttctg gataaaaaaa tagatagacc ataacgggcc
    44761 tatctatttg gtaaccggtg ctctcctgcc aactcctcgg tcacaagtca cactactcat
    44821 aaaacatgaa aagctgtttt ttgaaatcgt ttcttgtgac ttagagttaa acggtaggct
    44881 tacaacctct tcattaaacg tttttcaatc agctgacctt cggtattagc tcaataaacg
    44941 gcaaaatatg aggagcaatt tttccgttta ttgagctaat actcaggaca ggacgctgat
    45001 ttcacaacct ctagataaac ggtgttcaaa agccagtttc tcggtattaa gccaaattta
    45061 tgaaaaaatg tggaaagcca ttttcacaaa atttttctta ctactcgaaa ctaagcggct
    45121 ttttcacaac ctcttattct gaaaaataat ttcctggcac aaccgtaata tttttcgttt
    45181 gagtatctac atctttgaca taaagcagtg acgtataatc atcgatggcg cgatgaccgt
    45241 tgaattttga ttcggcaaat acagtgatgc caacaagttc tgattcgaat tcttcaatca
    45301 agctcttcat tccgttgact gttccgccgc ctttcatgaa atcatccact acaaggacac
    45361 gtgaaccacg tttcaaactt ctcttagaca gttccatctt ttcaattctt tcagaagatc
    45421 cagacacata gttgacactt actgttgatc cttctgttat ttttgagtcc cggcgtacaa
    45481 taacgaatgg cgcattcaga taataggaca cagcttgggc aataggtacg ccttttgtgg
    45541 ctacagtcat tacagcatcg attttttcac caaggtattt agaagcaatg attcttccaa
    45601 cttgacgcag cagttcaggt tctcctaaca aatcagagag ataaacatat cctcctggaa
    45661 gcagacggtc ttgttctgat agacgttctg ctagagattc aatatatttt ttcgcctctt
    45721 catatgaaat ttcagggatg aacaatacac cacctgcagc acccgggatt gtttccaagg
    45781 ttccataccc tcgttcttta aatgttttct tgatgattcc caaatcttca ctgatagaag
    45841 atttagcaga ttcataacgt tcggcaaagc ttgttaagga aatcaattca tgcgggtgat
    45901 tcaataaata ctgtgtcatg tcaactagac gttcactgcg acgtactttc acctattcca
    45961 actcctttta agaaatttta tcgttttaca ttatataagt ttttcttcaa aaattcgagc
    46021 attttatgaa aaaataagaa aatagttcgg tatttattaa aataaaaaga agcctataaa
    46081 aaatttttcg tttttataag gcttcttttc tttataattt agttattttt tcttctgaag
    46141 gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa gactaatgtg
    46201 attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga cagcatccct
    46261 agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc taatcgcata
    46321 ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc aatcgggatc
    46381 atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa atgaacgggt
    46441 agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg ccgtttgaat
    46501 aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac ttgctcccat
    46561 gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga attccctccg
    46621 ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat ggcaatggag
    46681 atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc tgctaataca
    46741 acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa cgctacccct
    46801 gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat cactaaaaac
    46861 acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc tcttctcatg
    46921 aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg atctgtctgt
    46981 ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat ttcccatgga
    47041 catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca tccatacctg
    47101 ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc gctaaactga
    47161 ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata tcccacatcc
    47221 ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga cgcttgaacc
    47281 agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta ggaaaacctg
    47341 cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt ccttcttgat
    47401 ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac gatgctttca
    47461 ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca cccgcatcta
    47521 catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc aaatcagata
    47581 tttcgatata acgcacctta caacctccat tctaaaactt aattgatact ttcttttaaa
    47641 gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat ttgttcatta
    47701 gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt cgacaatgtc
    47761 tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt gtttttcttc
    47821 acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg tgaaacgccc
    47881 gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc agcatgctga
    47941 gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg atccagtgct
    48001 tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt atctggatat
    48061 ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac cggatcgagc
    48121 caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc ttcatgttcg
    48181 tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat caaggtctgt
    48241 ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga actattatac
    48301 acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc gaaatcatgc
    48361 ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac gatctctttt
    48421 gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt tttgtctgct
    48481 tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac cgtagctgtc
    48541 aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt ttacgattta
    48601 ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc atcaatttct
    48661 gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg ctcatatcta
    48721 gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca gtttttcatc
    48781 acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt cctcacaaaa
    48841 accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca aggcaaaaac
    48901 ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca tacgctcttt
    48961 gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt ttcccatttt
    49021 tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt ggatgtcttg
    49081 atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga cactcattct
    49141 tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga tttcttcccc
    49201 tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg taccgacttc
    49261 caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt ggttgatccc
    49321 tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta ctggaatatt
    49381 cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta gcaataaagc
    49441 agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg tttctacaat
    49501 gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta cgctcgacat
    49561 caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca gtcctaaatt
    49621 tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa aagtctaagt
    49681 cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct agtggttgat
    49741 tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa caagttctag
    49801 tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc ctttttcttt
    49861 tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt tcctataagc
    49921 aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag cagactggaa
    49981 ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt gaaagaaaga
    50041 aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt ccgagtagcc
    50101 cattttctcg tatacaataa acagattggc taacagatag tcagctaatt cctcagattc
    50161 tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg gctgagcggt
    50221 gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag ataatacata
    50281 tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa gccatttttg
    50341 tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc aagtaaaatg
    50401 gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag acaagtcttc
    50461 tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac ccaattcatg
    50521 aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc ctaaacaatc
    50581 tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc caactggatc
    50641 tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt gatcttggtc
    50701 gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc ttgtagctgt
    50761 gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac tgccaagctt
    50821 cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg agatgcccaa
    50881 accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat gatttcctgt
    50941 tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa cgataaacaa
    51001 aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga attttgttcg
    51061 ataaaattct tttctggata accacacagc taacagaatc aagacatata ccaatatcaa
    51121 ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta aagcaatcgt
    51181 aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga gtaataaaaa
    51241 gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca ataatacttg
    51301 aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca tcatgatccc
    51361 cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa acagtcgcgg
    51421 aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca atagaagtcc
    51481 cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa ctactgctac
    51541 atcttgccga acagacaatt gactcattcc taagatcatc aaaacgtcaa aagtccccat
    51601 tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca taggatagat
    51661 cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata ccgcaagggc
    51721 tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg gataaaactc
    51781 gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg ctaaaaaact
    51841 accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa taaaaaagac
    51901 atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata gtgcgacttt
    51961 tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac tagcccgcag
    52021 acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg ttacccacgc
    52081 agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta agactctgat
    52141 cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca gaatcatgag
    52201 caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc aactcatgcc
    52261 attagcaata tttgcgactt gatttgccac aaagactaac acggagccga aaaaaatcag
    52321 ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt tatttttcac
    52381 attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc ttatttattt
    52441 taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa agatatccta
    52501 atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat atggcacaag
    52561 ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg ttcgtttcca
    52621 gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat gcatgcaaaa
    52681 gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa ccaaaaatca
    52741 ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc atttctattg
    52801 cttcaggaaa atcattaata gatttagaaa cagcgcttga agatcctcag gcctccatcg
    52861 tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg atttgcaaaa
    52921 atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa gcaatcggca
    52981 gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct ggcagctcac
    53041 ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg aatggtttgt
    53101 ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt caaaaattcc
    53161 tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct ggcggtacaa
    53221 ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc atcaaaggaa
    53281 tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga tagcaatgtt
    53341 ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt cttttgtatt
    53401 ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac tttgatgtgt
    53461 ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa acgaacagcg
    53521 tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc agcttgaact
    53581 gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact tcttaaacga
    53641 cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga gagcgcatct
    53701 gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg atgagaagcg
    53761 atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc accgatctca
    53821 acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag caacccggca
    53881 cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc taattttgca
    53941 acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg cagacgtccg
    54001 atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc tgcctcttcc
    54061 ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat ttcttcgata
    54121 cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg tgcgatttct
    54181 cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc gatgattaaa
    54241 tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc aatgatacga
    54301 cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga aacttgatct
    54361 gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc tgcttcttct
    54421 ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag ctcttcttca
    54481 gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat tttttctagt
    54541 tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc aattaattgc
    54601 tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt ttctaacgag
    54661 tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg agattttaat
    54721 tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg attttcttcc
    54781 ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc actatcgatg
    54841 attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga ctttgcgacc
    54901 ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat gttgaatacc
    54961 ataaaatcca cctccatact atctttttca tttttatcat ctatacagct tctatgataa
    55021 attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa catgcacaac
    55081 tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa acggctttct
    55141 acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat aggtaaacct
    55201 ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata tttttatttt
    55261 atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa aaaacggcag
    55321 gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat ttttattctt
    55381 ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact tcttcaccaa
    55441 taccataagc tgctctaact agagcagaaa cttctgccat catttcagga tgattagcca
    55501 tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa gaataccaag
    55561 caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct ccttcttgtg
    55621 agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt gctactttgt
    55681 tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt ttcaattgtt
    55741 ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt cctccaggag
    55801 tgatttctgg attcccaaac atcacgccta ctttttcacg gatttggttg atgaaaatag
    55861 cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga gacatcaaac
    55921 gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct cgtggaacta
    55981 aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact aaagcatcag
    56041 cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca tcgatattca
    56101 cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg aaagcggccg
    56161 ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt ttacctgaac
    56221 tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca cctaaagcga
    56281 catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt ttttcgccca
    56341 atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca gcatctaagg
    56401 ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat cagagcaaca
    56461 tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac cgaacaaata
    56521 ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct tgcataaccg
    56581 cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa accacgccgt
    56641 ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac gtgtccggtc
    56701 cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt gcttgaatgg
    56761 ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc tccggatcaa
    56821 tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct ggaaatactt
    56881 cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc aaactttccg
    56941 ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt gctagcgaat
    57001 tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt tcttctaatg
    57061 ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt cgtaatgtca
    57121 cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca atcagatctt
    57181 ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact ttagaaatta
    57241 gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc acaaacattg
    57301 gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct gtttgataaa
    57361 aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg ataatctggg
    57421 actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat gccaataatt
    57481 ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca gttgcttctt
    57541 ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt tcacttcttg
    57601 tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca actgtttgat
    57661 aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca ttcgtattca
    57721 cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc attacttccc
    57781 gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag agggcaagga
    57841 gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc tcctgccaaa
    57901 acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg aaattatccc
    57961 ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata cttacattga
    58021 tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga tagtaaagat
    58081 cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga atgggatatt
    58141 attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt ttcccggcca
    58201 agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg tgacggctaa
    58261 ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt caaccaacat
    58321 gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact tgccaaaatt
    58381 agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga tactagctaa
    58441 agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc ctacgttaaa
    58501 ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca tacaaattct
    58561 aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc ctattctacg
    58621 tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt tattcaaagg
    58681 agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga cacagatttg
    58741 tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat ttatacgatc
    58801 attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt tcccctggat
    58861 taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca ccaatcgtga
    58921 tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt gctgccagtg
    58981 tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga ttgacagcag
    59041 taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg gcactgccag
    59101 aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt gttgattcta
    59161 ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc tcgactgatc
    59221 cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga cgatcttgcc
    59281 aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat aaaatgacag
    59341 gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct tttctagaag
    59401 tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg cttttcccat
    59461 caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat tgccgaataa
    59521 atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg attgcttcca
    59581 aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt tttttattca
    59641 ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca tcttctccag
    59701 tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt tgggtgctgt
    59761 gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct gccaactcct
    59821 cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact tgttccttgt
    59881 gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca atcagctgtt
    59941 cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt atgtttctct
    60001 aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt caaaagcttg
    60061 catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt tacttggctg
    60121 ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg tgttccagaa
    60181 gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat tttcgtaaat
    60241 tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta cttcgtttga
    60301 ttttatttta atataagttg attaaaagag agcatgattt gttttatttt ctcactaatt
    60361 tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc tactacaagt
    60421 ctaaaacgaa atttaagact tttcctcata aaatactggt ttattttggt ctcatgtaaa
    60481 actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg tctttcattt
    60541 ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat aaactttgcg
    60601 taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt ccaagcattt
    60661 tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg aatccaagaa
    60721 tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg ctgaagtccg
    60781 caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg ataattcctt
    60841 gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg aacaacagat
    60901 tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg tctaatcctt
    60961 taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt tgtttgatga
    61021 tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg aaattttttg
    61081 cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta ccaactacaa
    61141 ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag tcttgagctg
    61201 tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg tgtgtaggat
    61261 acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca tacatttgga
    61321 tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag taaggtgctt
    61381 gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta gaaaacagat
    61441 agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc ccaaataatt
    61501 gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg gcaattccat
    61561 ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg atcgaaccat
    61621 aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac aaatacacgg
    61681 tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca tattctgttt
    61741 tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat ttgctcagct
    61801 acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc ttcatcagat
    61861 aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc ttgcggagag
    61921 tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag ttccaactct
    61981 gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag tacttgattt
    62041 cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt atccacgcta
    62101 ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag tttagagtga
    62161 ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg ttcatcgtaa
    62221 tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc acgtacttgt
    62281 cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata aactgtttcc
    62341 cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc aacatcgccg
    62401 acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga cgctagcgaa
    62461 ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt ttgttccggg
    62521 ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt atcttccttc
    62581 aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa ctgatcaaac
    62641 tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac cgcttgagaa
    62701 aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc gtttagccaa
    62761 tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag ctctgcaagt
    62821 tgcgcactta actttgtctg atccgaataa ttcaaactat ttgtttccaa catgctgctg
    62881 agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg gataaaaatc
    62941 cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc tgccaattga
    63001 tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt ttaatgggtc
    63061 aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca attcgccgtt
    63121 ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca aaagaaacag
    63181 acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta aagacaaata
    63241 aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc gtggagatgt
    63301 cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg taaaccaagt
    63361 ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca caggtacttc
    63421 tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg tcacatttgc
    63481 gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg tcttattctt
    63541 agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc aagtggaagt
    63601 ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc ttgccaaaca
    63661 agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata cttctaaata
    63721 ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt tttagattct
    63781 taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc caaatacaca
    63841 tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc ttgtgcgccg
    63901 atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc ttgaacaatc
    63961 tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc aaaatggata
    64021 ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt atcttgaaaa
    64081 aacgtatgcc aagcttctcc atcaatgtca tcaacttctt gataaggaca ctgttgttcc
    64141 acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt tgacaattct
    64201 tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt attcttagca
    64261 taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg tttgcttttt
    64321 aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct gaatagctgt
    64381 aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat actgaaggat
    64441 aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc tgagcaacca
    64501 acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct aaagttgttg
    64561 gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt caagtttacc
    64621 ataaaaaaaa aagaaatgca ataaaaataa ataagaagct cattaagatt tttctaaatt
    64681 attcctcatt ataaaatttc aagtgttttt ttattttgag ttttactctc ccgtaagcgc
    64741 tcattacttg cttgtgatcc attgctaaac attcagccat gtctacaaaa tcaacgcctt
    64801 gcatataata atgaaaaatt ttagcttcta tttttgaaaa ctggatttcg caattttcga
    64861 ttgcttcttt taataaaaga tgctgaattg ctaaaggttc ttgcaatgtg atctctgcta
    64921 aaaagtctgg tccttctgtc tctatttttt ggtcgattga gacttcatct ttttgatcac
    64981 gacgcttcag cgcgttctgc ttcctcaaca gagaatagat ttgattgctt ataacgcttt
    65041 tataataact tccaaagcta acacctttgc ttttttcgta agttctcaat gcctgatata
    65101 aagcgatcct tgcttcttgt tcccaatcct cagaaacata atttcttaaa taataggtgt
    65161 ttttcaaacg tagtaaaagt ggaaaatatt tttgatacag ggcagcaaat gcttcttcgt
    65221 caccattacg tgcagcgcgc aataactcct cagacataaa ataattcctc cataaattcg
    65281 tttatggagg aatcttatca tcaatgattc atcgaactga ttagaacgat atgttattta
    65341 ttttttctca ttaaatcgtc caatttttgg gacaattttt ttaactgctc ttcattccat
    65401 ggagaattac gtcggaaatc aataaaatgc atatctttat tttcttgggc tattgttttt
    65461 tccgtttttt ttatcgtctt atataattca taagcagaag ttcgtaatgc tccttgggaa
    65521 aagatcatcc actgttctgc taaatcgctt gtcgccactg tcacttgtgt caaacggtca
    65581 ttcagctgac cagcgattct ctcgatataa ctgtcagccg tttcgtcttc tttcgtaaaa
    65641 acaacatcca actggtattt cttataattt tgttggatgc ccggaactag ttgggcatcg
    65701 aagacaacga tgacttccat tccttcatat ttcgcataat ttgataaacg atgtaaaaga
    65761 gcttctcttg catccgccat tttgtcctgc tttttaagct ggacaagttc cggccacgaa
    65821 ccaatcatgt tgtagccgtc tacaatcaac agctgttttt tcatggtcta ctccccctga
    65881 cgttgggaaa aagcctgata cataagcaaa ccagcagcaa cactggcatt taagctctgg
    65941 acgtgcccgg tcatcgggat cgtcagcaat tcatccattt cttttttcaa tcctggactc
    66001 attcctttgc cttcattacc aatgactaaa gcaattgatc ctttggcatt ccatttttgg
    66061 aagtttgtgc cggtcatatc tgtgccaaat acccaaaatc ctgtttcttt gagctgttgc
    66121 acagcttgta ccaaattcgt cacgcgtgca acagggacat gttcgactgc cccagtggaa
    66181 gtctttgtta cgataggtgt gattccaact gctcggtgtt ttggtatgat cacaccatcg
    66241 acgccacttg cgtctgctgt ccgtaaaatc gacccaaaat tgtgtggatc ttcgatgcta
    66301 tccaaaatca aaaagaaggg gtcttctttt ttctcttttg ttcgttcaat cagttggtca
    66361 agggataaat attcataagg tgtaatcgca agaacgactc cttgatgcac gccgtgatcg
    66421 ctcaaagttt ctaatttttg tttaggaacc catttgactg gcacagcttg ttcacgtgcg
    66481 atttctttca gttcttctac tttttctcct cgtgaatctt cttgaagaaa gagtttattc
    66541 cctcgccctt gttgtagcgc ttctactgcg gcatggtgcc caaagacgaa attatcttct
    66601 aatgcttctt cattttgatc agaaactgac tgatttcgtc cagtttgctt tttatttgaa
    66661 tatctatttt gttttttgtc ttcaaatcca cgtttcgatt gatgtttgtt tgttctttct
    66721 ttacccattt ttttcaccaa ctttctgaat acaccagcgg atcaattctt ccatccgctc
    66781 ggtttgtttt gtcaaatgca gatagcccat gagcgcttcg aaccctgttg cgacccgata
    66841 cgtcgtaaca tcagcatttt ttgtgctcgt atggctttta gcatttcttc ctctgcgata
    66901 ataaagttct tcttcttctg tcaaaagatg ttcttccagc atttgctgaa tcaaaaaggc
    66961 ttgtgcattc gcagaaacat aattcgttgc cgcacgatgc agcttattgg gttttgtttc
    67021 tccttgatca atcaggtggt cacgaacata gatttcgtaa atcgcatctc caacataagc
    67081 caaggctaaa ccgttcaatt gtgtgtaatc tctcatgctt ctcttctcca tcgggttcct
    67141 tgcggtgtat cttctaataa gatccctttt tctttcaaca aatcacgaat ttcgtcgctt
    67201 cggacaaaat cacgattgct tcttgcttga tttcgttctt cgatcaattg ttcaatctct
    67261 tcatctaata actcttctgc tgtaaataaa ataccgaaga tcgaaagcca ttgcgagaat
    67321 aaagcttctc cttgtgccaa gacagcggca gaaactttcg gctggtctag ataagtgttc
    67381 agccacttag caagctcata gaccactgtg atcccatttg ctgcattaaa atcatcgtcc
    67441 atttcttcga tgaatcgctg ttctaaattt tctaacaaag cgattttatc cgcatcatct
    67501 gccaaattct ctgaggcagt ttcttggcgg aatttcaaat tgtcaaacgt attcttcagt
    67561 cgttgtaaat tggtggctgc ttctttcatc gtcgtttcac tgtagcggat cggacgacgg
    67621 tattgtgtgg tcgccatgaa gaaacgcaag acttgtggat caacgttttt gatcatttca
    67681 tgtacagtga tgaaattccc tagagattta ctcatttttt catcgtcttc gccaatcgtt
    67741 acatagccat tgtgcatcca gtaattagcg aattttttcc ctgttttcgc ttcactttgt
    67801 gcgatttcat tttcatgatg aggaaattct aaatcttgcc cgccaccatg gatatcgatc
    67861 gtttctccta aatgttttgt tgccataacg gaacattcaa tatgccaacc gggacgtcct
    67921 ttgccccatg gtgaatccca agaaatctcg ccaggttttg cttgtttcca taaagcgaaa
    67981 tctaatgggt cttctttttg ctgctgttct tcccctgtac gctgacttgc tccgacttcc
    68041 agttcatcga tggattggtc acttaatttc ccataatttt caaatttacg ggtacggtaa
    68101 tacacatcac ctgaagattc ataagcatag cctttttcaa ccaacacttg aataaatgct
    68161 aaaatatctg gcatatgatc catgactctt ggatgcagtg tagcaggttc gacattcaac
    68221 gctttcgtat cttcttcaaa tgctcggatg aaacgatcag caacttctgg tgctgtaata
    68281 cctaattcgt ttgctgtacg gatgatttta tcgtctacat ccgtgaaatt cgatacgaaa
    68341 tcgactttat agcctcgata ttcaaaatag cgtcgaattg tatcgaaagc aatggtgcta
    68401 cgagcatttc cgatatggat ataattatac acagtcggtc cgcagacata cataccgaca
    68461 tgtccctttt gtatagggat gaattcttct ttttttctgg tcaatgtatt gtagattttt
    68521 atcattctga tctcctcact ttttctcctt tgattcgaac gacttttgct ggtactccta
    68581 ccgctgtagc gtcgtctgga acatctttca acacaacggc acctgcaccg attttggcgt
    68641 tttttccgat cgttaccggt cctaatatct gcgcattcgc agagagcatg gctccttgtt
    68701 taacagttgg gtgtctttta cccgtttctt ttcctgtgcc gcctaatgtt acgccatgga
    68761 ataaaatcac atcgtcctcg atttctgcgg tttcgccaat gacgattccc attccatggt
    68821 cgatgaacac gccagttcca atcgttgctc ctggatggat ctcaacacca gttaggaaac
    68881 gccagaattg agcattgatc ttcgccaata aaaagagccg gtgctgatat aaaaaatgag
    68941 agaaacgatg ccaaaacaag gcatgaaaac cagggtatgt caaaacgatc tcagctgtcg
    69001 aacgtgcagc cggatcgttt ctctttgctg catcaatcgc tcgggtaaac caactcatga
    69061 ctttccactc ctttcgtaag aattttatgt aggaaatcat cttcttataa agaaaagaag
    69121 cgccttttaa ataagtttcc ttatcaaaag acgctttccg cgtggttcca cttttcttca
    69181 taatcaatga ttatctctga cagctaacgc ctgttatacg ttcttggcta ctttgtttcc
    69241 tataaaacag tttttcctgt tttctgtgtt tcgccaagac cactcccaga ggcatttcgg
    69301 caaccattca ttgatacctt gcaccacccg gtatctctct tgtaatgatc agctgcttac
    69361 ttttttctgt tcatcgtgtt tagttcagta cttgatttaa atgtgctaat gatttttcac
    69421 gaccaagcaa ttcgatcgtt tcaggcaatt ctggaccatg catttgtcct gatacagcta
    69481 cacggattgg catgaaaaga ttttttcctt ttacgccagt ttctttttga acagctttga
    69541 tggcagcttt gacagttgga gcatctacta cttccatttg ttctagctgt gctttgaatg
    69601 cgtggagaac agtaggaact gtttcaccag caagtacttc ttttgctgct tcattcaata
    69661 caggatgttc attgaaaaat agcgtagaca gatcaacgat ttctgcagca tagctcattt
    69721 gaggttgata caggctaacg atcttcttca cccattcgat tgtcttttca tctgggtttt
    69781 ctgctacacg tccatcagcg attagataag gcagacacat gtcagtaaat gcatctagat
    69841 ccattgcttt gatgtaatgg ttgtttaccc attgcagttt tttcgcatcg aaagctgcgg
    69901 gtgatttact taggcgtttt ggatcgaaca ttttgatcaa ttcttggtgt tcgaagattt
    69961 cgtcttcgcc cacaggtgac cagcccaata atgcaataaa gttgaacatt gcatctggta
    70021 gatagcctaa ttcgcgatat tgttcgataa attgcaagat tgattcgtca cgtttgctta
    70081 gttttttacc tgtttcactg ttgatgatca atgtcatatg tccgaaggtt ggtggtgtcc
    70141 agccaaatgc ttcatagatc atcagttgtt ttggtgtatt ggcaatatgg tcatctccac
    70201 gtaaaacgtg agtgattttc atcaaatgat catcgaccgc aacagcaaaa ttataagttg
    70261 gcataccatc gcgtttttgg atgacaaagt cgccaccgat attatcggat tcgaacgaaa
    70321 tagcgccttt caccatatct gtaaatgcgt attctgtatt gcgaggcaca cggaaacgta
    70381 caacagattc tagaccttgt gcttcttttt ctgcttgttc ttcaggtgtc aagttcgcac
    70441 atgttcctgc gtaatgaggc atttctcctc ttgcgcgttg tgcttcccgt tctgcttcta
    70501 attcttcttc tgtgcaatag catttgtatg ctcgattgct agcaagcagc tgatcaatca
    70561 gcggttgata gatttcttta cgttcagatt gacggtaagg gccgtattct ccaggatttt
    70621 caggagattc atcccaattc attcccaacc aagcaaggtt ttccaactgg cttttttcgc
    70681 catcttcgat attacgtttt tggtcagtat cctcaatacg aataataaag tctccatcat
    70741 tgtggcgggc aaacaaataa ttgaataatg cagttcttgc atttccaata tgcaggtgcc
    70801 cagttggact tggtgcatag cgtacgcgta ctttcgtcat tttcttcctc ttctttcaaa
    70861 ctagactttg actaacagca aaaattccgt cagttacggc ttctcaaata tcatttattt
    70921 aaagccactc agcacaaatt ttaccttttc taaggtaaat agtaaagcca actggttgaa
    70981 tttccttacc agttggctga atttcttttt tattttgatt gtttagtctt tttctctgtc
    71041 tcttttttat tgtcgattcc tcgtcctgca tgtgcaggtt tagcaaagat catgcgtcca
    71101 gcagctgttt gaagggcact tgttacaacg acttcgatac gttcattcat gtaatgctgt
    71161 ccatcttcta cgacaaccat cgtgccgtca tcaaggtagg ctactccttg ttggcgttct
    71221 gtcccggctt ttactactag aacattcatc gtttcaccag ggatgacgac tggttttacg
    71281 gcatttgcca acgcattgat attaagaaca ggtacatttt ggaattcaga gactttattc
    71341 aagttatagt cattggttac aatgacacca tctaaaagct tagccaattt gatcaatttg
    71401 ctgtctactt cactgatatc ttcaaagtct ccatcgtaca tttcgacaga tataccctct
    71461 tctttttgca aggcatttag gatatctaat ccgcgacgac cacgcacacg tttcaaacta
    71521 tcccctgagt ccgcgatgta ttgtagttcg taaagaacaa aattagggat catcaaggtt
    71581 ccttctaaga atccagtctt tgtaatatca taaatccgac cgtcaatgat cacgcttgta
    71641 tccaagattt tatatttatg gaaattttct cctgattttc gttctaacag ttgactctca
    71701 acttgactag ctgtttcttg ctcgattttt ttgcttcgtg aaccaaaaac tttcttccat
    71761 tcttcgattc gtgtcgttcc cattctcaat cccagatagc ctaagatgat catcagtaaa
    71821 atcggcaata cactattgac gaatggaatt tccatattgt aaagaggggt cgagatcaca
    71881 acacctaaag tcaatccgat gatcgcaccg atcgcaccga agagaagata agtcaagctg
    71941 acctcactta gtttttgttc tacttgtttg ataatagctg agatatgttt ggccaacagc
    72001 aaagataata aaaagaaaat aagtgcgcct aacaggctgt tggtaaatgt attattcagc
    72061 catccgtttg actgttgacc gattgcctgc caagctgagg gtaaaaatga aatacccaag
    72121 cttgcgccga caatgatcat cagcaaagta atgacacgtt tttgcatcgt ttttcctccg
    72181 tttcgacaat catttattag ttagcggaac acacgcttca acgtttcagc caaagttgct
    72241 actccaacta tctcgattcc ttttggcgct tcccagttac ctaagttgtt tttaggtagg
    72301 tatacttttg tgaagccgag tttttggact tctttgactc gttgttcaat atgactgaca
    72361 cgtctgattt ctccagtcag tccaatttca ccgatgaaac attccgttgg ctgtgttcct
    72421 ttttctttat agcttgaagc aatactgaca gcgatagcta aatcaatcgc tggttcattt
    72481 aattttaccc cacctgcagc ttttaagtaa gcatcttgat tctgaagaag caacccagct
    72541 cttttttcca gcactgccat gatcagagat acccgattga aatcaagacc tgttgttgtt
    72601 cgtttggcat ttccgaacat agtaggtgtg actaatgctt ggatctctac caaaattgga
    72661 cgtgtccctt ccattgccac aacgatagca gagccagttg caccgtctag gcgttcttct
    72721 aagaaaatct gtgaaggatt agcgacttct tccaatccat gctcatgcat ttcaaaaatc
    72781 ccaatctcat tcgttgagcc aaatcggttt tttactgctc gcaaaatccg aaaactatga
    72841 tgttgttcac cttcaaaata taacaccgta tccaccatat gttctaacat tcttgggccg
    72901 gcgatcgagc cttctttggt aacatgaccg acgataaaaa tggctatccc atttgtttta
    72961 gcggttttga gtagttctgc agtggtttct cttacttggc tgacacttcc tgccacactt
    73021 gtgatgtctg gctgcgtcat cgtttggatg gaatcaatga taacataatc aggggagata
    73081 tgttcgatgg cacgactgat ttcgttcata tctgtttcag cgtatagata aaattctgtg
    73141 ttgatacttc cgaggcgttc cgcgcgtaat tttatctgct ctgcgctttc ttcgccggat
    73201 acatataaga cttttccgcc tatggctgct aattgctgag aaacttgtaa cagcaaagtg
    73261 gatttcccga tacctggatc gccaccaatc aagaccatag accctggcac cacacctccg
    73321 cctaacacac ggttcagttc ttctaatttt gttttgatcc gaggttcttt tttagggacg
    73381 acgtctgcga tttttgttgg ttttgctttt tctcctgtca aacttgtccg agttctgcgg
    73441 tccgttgtat cttgttcgat ttcttcgacc atcgtattcc attttccgca atttgggcag
    73501 cgtcccaaga acttaggcga cacatacccg caattttggc aaacaaattg tacttttgat
    73561 ttttttgcca ttgtaccgcc tccttttatc ctaatcatga gacattaaat caagcttaag
    73621 tatctttaac gttttattta ctggaagaac caaatccgcc ttgacgttga gcagtcgttt
    73681 gatcttgatc tgcttttaaa aacggcaaaa agatcccttg gccgatacgc tcgccttttt
    73741 tgatcactac atccttgaaa ccaaagttgg tgaattggaa catgatatgg ccttcatttg
    73801 cctcattatt gtaataatca ctgtcaatca cacctactcc gtttgtcaac actaaaaacc
    73861 gcttcaacgg attgcttgaa cggttagcaa gctgcaaaaa ttcatcttct cccatgtaag
    73921 ctttgattcc agtaggcacg agggttggtt tcaattgttt ttcattttct gatacatctt
    73981 ttttcaatcc atctgcgact gtttccaacc cctttttcca gcctgctttc cagatacttg
    74041 gaatcacgac ctcttctgct gcttcaaaat catagccagc agcatgatgt gtagcgcgct
    74101 gcggtagatt gatattttga tctttatatt tagaaataac ttcaaatcct ctttttctca
    74161 ccggttttcc tccctaaata aactactcct attctaacat atccgaggct gtaaaagact
    74221 ttctttacaa attcttcaag aaattctgct atcttaaagt aaaccattaa ttcgttcttt
    74281 ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta catgacttta ctcgtcaaaa
    74341 caagtagaat agaacgaaat taatgagtgg atatttgatt gaggtgtcac atgcgtaaag
    74401 aaattaaaaa tgcaaaacga attattgtca aagtaggaac aagtacattg atttatccca
    74461 atggaaatat caatcttgcg gcaatcgatc agttagcttt tgtcctttct gatcttagaa
    74521 atcggggaaa ggaagtgatc ttagtctcat caggagctgt aggcgttggt atgcataaat
    74581 tacatttgtc agaacgtccg actttgattc ctgaacagca agctgcggcg gctgttggtc
    74641 aagccgaact gatgaatatc tataatcaaa gattcagtgt atataatcaa cagacggcac
    74701 agatcctcgt gacaagagac gtggtagatt atcctgaaag tcgtaaaaat gtgaggaata
    74761 cattggaaca gcttttgatt atggacacga tccctatcgt gaacgaaaac gatactgtag
    74821 cagtggatga attagatcat ctgacaaaat ttggcgataa tgatcagctg tcagccatca
    74881 tggcaaaaat tgtcgcggca gaccttttga tcgtcctttc tgatatcgac gggttttatt
    74941 cagataatcc gactacaaat cccgaggctc agatgtatcg ctatatcgat aaaatcgatg
    75001 aaaagattct ggcacaagca ggtggtgctg gtagcacatt tggaacaggc ggtatgcaga
    75061 gtaaattaaa agccgcttct aggatatttg aagcaaacag cgcaatgatt ttagcaaatg
    75121 gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa agaagtaggt actttattta
    75181 aggaggactt gaaatgactg acttgatgca attaggacaa caggcaaaag atagcgcgca
    75241 acaactagca cttatgccta caaaccgcaa aaatgagcta cttgttcaaa tggcacaaac
    75301 catcaaaaag aatcaacaag cgatcattga agcaaatcat aaagacttag aaaaagcagt
    75361 cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag ctgacacctg agcgaatcaa
    75421 tgccatggct acagagatcg aaaaaattgc ttcgttagac gatcctattg gaaaagtaga
    75481 tgagatgtgg acgaacaccg acggattgag aatcggcaaa aagcgcgtgc cactaggcgt
    75541 gatcggcatc atttacgaat ctcgtccaaa tgtcacgaca gatgcagcta gtctagcatt
    75601 caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa gcattcttct cgaatcaatt
    75661 attagtccaa ttattgcagc aagtactggt cagtgctggc gaatctcctt atgccatcca
    75721 gtttgtcgat gatacttctc atgaaactgc aggacagttg atgcgattga cagaatactt
    75781 agatgtgctg attcctcgag gcggagcaaa attaatccaa cgagtcaaag aacaggcaac
    75841 ggtacctatc attgaaacag gtacaggaaa taatcacgta tatatcgata aagaagcaca
    75901 gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct tcccgtccat ctgtctgtaa
    75961 cgcggcagaa acattgctga tccattctga gatcgcacct tttttcttgc cagctattga
    76021 aaaagaactg gtagaacacg gggtctcttt acgtgcggat gctcgtgcgt tagaatatct
    76081 agagacggct gctttagcag aagacacaga ttgggatact gaatatctag attatatcct
    76141 tgctgtcaaa gtggtcgatt ctttggatga agcaattgca catatcaatc ggcataatac
    76201 taaacattca gaaacgatcg tgacagatag ttatgcggct agtcaacgtt tcttaaatga
    76261 agtggacgcg gcggctgtct atgtcaatgc ctccactcgt tttacagacg gatcggtatt
    76321 tggttttggt gcagagattg gtatctctac tcaaaagttg catgcccgtg gtccaatggg
    76381 gttaaatgaa ttaacttcca caaaatatat catttatggc gatggacaaa tccgcgaata
    76441 atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt tctgtaaagg ttctatccaa
    76501 ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt tttatttacc ttatttctct
    76561 gaatatcgct gcttttctgg gagtcggtat tttatccctt ttctttcaat tcaaaaaacg
    76621 aagcataggg agtcaacggg aaaaatggtc gcagtatttt gacaaaatcg ggcaaaaagg
    76681 gctggttaca cgcttgcaca ttagttacat ggttgcatta tgcttattag cgacaatcaa
    76741 ttactattct tttttcgatc attcaatcgc ttatacgatt acgctactga ttgctgggat
    76801 ttttcactta tcttataaat atcagctgaa taaaaaccac ttgaatcgga ctttccgcta
    76861 aaaaatatcc gtacgataag tagagtgcct tgaagatcgg caaaaaactg ccggactttt
    76921 tagaggctgt gacaaagatt ttgtcacagc ctctttttcc atataaacgg cgttcgccta
    76981 ccagctgcct ggtaaatctg tttcctcttc gttaagaagc gaaaatccgt caaatgtttc
    77041 gccatcataa taacgaagca gctcatccat ggacaagttc atcgtttttt ctttttcttc
    77101 ttccgctgat tcagccagta gctgttcccg atacacctga tacataccag ctattttttg
    77161 ctgcatcgct tttctagttt caccttccgc attgattatt ggcaattctt tgatatagcc
    77221 acgataaatc aaccgatcat ctgaaaattc aatgggtaat tcaacgagtg tcaacccgac
    77281 ttcctgaaaa tattcttcca gcatctatta tccccccatt ctttttctta aatgaatttt
    77341 agcttaccta ctgaaaattt tccagtttca ttattttgag aaaaaaaggg aatgtgacaa
    77401 aaatcgtgtc acatcccctt tttccgaata aatggtgttc ttctgccaac tcctcaatca
    77461 taagtcacaa tattcaacaa acatgagaaa ctgttttttg aaattgttcc ttgtgattca
    77521 gagttaaacg acagtctcac aacctcttgg taaacggcgt tcaatcagct gaccctcggt
    77581 attagctcaa aaaacggtaa aatatgagaa gctatttttc cgttttgttt ctctaatact
    77641 taggataaaa cgctgatttt acaacctctg ttaaacggtg ttcaatcagc tgtccttcgg
    77701 tattagctca aaaaacggca aaatatgagg aactattttt ccgtttgttt ctctaatact
    77761 caggacaaaa cgctgatttt acaacctcct gataaacggt gttcaaaagc ttgcatctgc
    77821 ggtaataagc ccaaccaaac gaaaaatatg agaagctatt tttgtttggc tgttcttatg
    77881 acttgatgca ggacagcttt ttcacaacct ctgatttctt attcttcttc atttgtagca
    77941 aaataattac ggtgataaat gatacaacat acactgataa gaacaatggc acctgcaaaa
    78001 taaaacgcat agctttcacc aatatgttca ccaatcacac ctgcaataaa tggtgctaaa
    78061 gctccaccga aaaagcggac aaaactatag ctggacgaag caacgtttcg ttgcagacct
    78121 ggtatttcca tagcaatcgt cgtcaacagt gtattgataa ttccttggaa aaatcctgct
    78181 aacacaatgc tgatcggtac aaggactggc atagaagttc cagctcctaa taacagcaaa
    78241 caaataatga ataagacaaa tgctgctaaa attgtccgat aagtcgtaaa cttccgctca
    78301 agagccggtg caacgaaaat cgaagcaata gccagaagca caccccagcc aaaaaataca
    78361 aaaccgactt ctaattcaga atagccaatc aataaaaatg gcgcatacgc aagtaaagta
    78421 aagaatccga aattatataa caatgcgatt agtccaactg aacgaagttt atgattgctt
    78481 aacgctttga taccttccca aaggcctact tttctctttg gtttctcagt ttcaggtaaa
    78541 agtaccgcta gggctataaa accgcaaaac atcaaaaatg ctaccccaaa aaatggataa
    78601 cgccatgaac cactgcccaa gaccccaccg actagagggc caacagccat tccgcagcca
    78661 agtgctgctt catacatcat gattgctttt tctgtgttac caactaaaat actgacgatc
    78721 gttgctaaag cagtagagac aaataaagca ttcccgacac cccagccggc acgtaaccca
    78781 atcagcattc cgatattccc agataatccg ccaagaccag cgaatacaac gatgataaac
    78841 aatcctgtca tcaatgtttt tttcaaaccg atccgactag ataagaaacc tgtaaatagc
    78901 atcaccacac cagtgactaa catgtaacta gtaaataaca gggtcgtttc agctggcgta
    78961 gcgtttaact gtgcagcaat cgtttttaag attgggtcta ctagacccac tcccataaaa
    79021 gcgatcatac aggtagctgc tacaactagc gctgaacttt tcccctttgt ttcttcattt
    79081 gtttgttctt gtatatctat ttgattctcc aatatttcca tccctttctc tctattagca
    79141 tcatacatga tttattttac atgtcaatat gcacatgtaa aacgtggaaa ctttactgtg
    79201 atataataaa gaaaataaga cgagaggtag gatttttatg aatactttag cctatatatt
    79261 attatgcgtg cttttatcca aaccacgttc tgggtatgaa ttgaagcagc tgatcacaat
    79321 tttttgggaa gcccatcaca gtcagatcta tacaacgctt gccaagttag accagcaggg
    79381 ttatgtgacc gttttggaca aagacgagca ctctcaaaaa aagatctacc acttgactga
    79441 tgaaggacgt gctcttgtag aggaatggat caaagaggaa actcccgctc ctacgcaaaa
    79501 agatgaattt ctagcaaaaa tctatgcttt ttcgacgctc gataaaacaa cagctactgg
    79561 actgctattc actagagaac aacagctgaa caaaatcatg caaaaaaatc aaaaaaaatt
    79621 gaatgacctc tcgctagaca agaaacaaga atttggacgt tatgttgtga tccagcgcag
    79681 aattatgctt tgtcagcagg aactccaatg gtgtcagcaa gtaagagaac aaatgcagca
    79741 gttttttgag taagggataa acagaacctt tctagaaata tctattgaag agcaaattat
    79801 cttcaataaa agagcaatac agttggaaaa gaaaaagcga tccgaacgac aggccaaaac
    79861 ctatcgttcg gatcactatt tttctagaac tgcattcaag agactatgac aaaaagcatg
    79921 ccaaggcctt ttttcaaata acagtgttcc atcattcatt actttgaatt gcttttagca
    79981 cacttcttga aagcgggcca acgatgatca actgcaacgg taaagcggca atcacattca
    80041 ttttccaagc attcatataa gcagagaata attgatcagg tattccttgt tccatgatca
    80101 caccgaataa agacatacat gtcaccattc ctaaaaccat caagcatgaa atagttaaga
    80161 tcatttggac cttgctttct ggatttactg gtagtttaaa ggcaattttt ttcgccagca
    80221 caccgatgat gaagacatcc aaaatgaaag ccaccacgaa tccaggcact agaccaatca
    80281 acaaacttga taaatgaaga tcttgatgca gccataaatt atacgcgctc atccccaaga
    80341 ccatcaaaaa acacatcatt gttgtaaaaa ttattccttc ttttttattt gtaggcaatc
    80401 tgtaccactc ctttaaattt gtcacgaaaa tcatcgtagc acatttaaaa atttctcgta
    80461 agtacttttt ttattttctg cccttttatt tcataaactt catcagccgt acgctcgaca
    80521 aagtaagaat catgagaagt aaacaaaatc gttcccggat atatttgcat tagcttctct
    80581 aaagcttcga tcgttgccat atcaataaaa ttagtcggtt catctaacag caacacatta
    80641 cttggcttag taaaaagcaa agcaatcgtc agacgggtcg cttctccccc acttaatgta
    80701 cataacggtt tcgtcaaagt ttcctgagca aaccctaagt gattcagcaa actacggaca
    80761 agcgattctg aaaactctgt ttgtctcatg acaaaacgaa tgatggattc ttcagatgtc
    80821 atttgataac ccttttgctg atatacttga aagcttactt tcggagagag aaggattcct
    80881 tctccttgtt tgcggatatg ttctaataag gttgtcttac ctgaaccatt ttcaccgaca
    80941 atcgcgattt ttttacctaa agaaaactga aaatcaccat ttaccagtaa tgttctccca
    81001 cttctttcca attggacatt ttgtcccatg atgggatagc ggctgtggag ttcaagagat
    81061 tttggtactg gaaaacggat ttgtttcatc tgctgcggct tggttgtttc tcctattttt
    81121 tggagtcttc tctctaatgt tttcgcattc ttttggatgg ctttttgtac actgtctttt
    81181 tgtttagagg aagacaaccg atccagtctg atttgttgct ttttcttttt actggacact
    81241 ttttccaact tttccgcttg ttttttcttt tcttggatcg atttttccaa tcgttttttc
    81301 tctttcatga tcgactctgc ttctcgtagc tgagtctttt tctccaattc cttttgagtg
    81361 agataggcac tataattccc cgaaaactct cggatttctc cgtcttttac ttcccagatt
    81421 ttcgatgcta gctcatctag aaaatagcga tcatgactaa caaaaaccag cgtaccataa
    81481 taataacgaa gctcttcaat cagtcgatca atactttttc tatctagatg ggttgttggc
    81541 tcgtctagaa gcatcccttg ttcataagaa gaaagaagac gtatcaactc gatctttcgt
    81601 tcttcccctc cgctccattt ccgctctgaa gtttcttcca gtcttaactg gaaatgactg
    81661 gctaattcca aatttaggtc ctttgcttca gcgagatagg ttaattgagg caggtagttg
    81721 aaggtgatct ctgtttggat tttcccatga tcgggaaaaa gttcaccggc tattagtttg
    81781 agcaaagtcg atttaccgac accattttct cctatgatcc ctatacgatc ttgctgatag
    81841 acacgaagag aatcaataga tagttctagc tggttgccaa agctgacttg tagatttgtt
    81901 atatttactg ctaaattttc catatgtttt acactcctat ttcatgtaaa acaacaatta
    81961 tcgatactaa aaaagagcag aaaaatctgt ttgcaaaaaa actgcatcac atcttttcct
    82021 actctgaacg aaataactat gactaaatca ccaaatctgt catagctttc acctattcta
    82081 ctgtcgttcg aaaaaatgga catactccat ccatgaaatt gttgtttata catgtctttt
    82141 gaatttattt agttgttatt caaaagttcg aaacgtaatt tcatcgatgc agtcattttt
    82201 ccgacctcct tttttattag gttaccacac acgattcaaa aaaagcaata gctactgaat
    82261 agtaactgaa aaccttttat tcgaacatag tgatcttttc tggtgctaaa cgaacagact
    82321 cgtaaccttc ttctaccgct tttcctattg ataaaataat aactggaaca taacggtctt
    82381 tatccaaacc aaatgcctct gccaactgat ctgcttcgaa tccaccaatt ggatttgttt
    82441 catagccatg atcacgcgca actaacatga attgcatagc cgctaagcta gaatcgactt
    82501 tgactacatc gttcatttct tctcttgaaa aactcttgta ataaggaatg atcgcagcta
    82561 attgttgatc tctgacttct tttggcatct tccctgattc gtaagcttgg ttgtagattt
    82621 cttcgccata ttcgtaacat tgcatatcgc caaaaatcat gaccattgca gaagaagtat
    82681 cattttgtct cgtattgaaa cggatcaaag gacgcaagat ttcttttgct tcctcgcttt
    82741 cagcgaccac aaagcgccat ggtttcatat tgacagaaga aggtgcagtc gtcgcttctt
    82801 tgatcatttc cagcatttct tcgtgtggga ttttgtatgt ttcatcatat acgcgaacgg
    82861 atcttctacc agtcataatt gttgaaaaat catttttttg ttccattatt attaacctct
    82921 ttcgtttctg ttgttatatt gcaaagttgg gtattcaatt tatctaaaag tgttagaaat
    82981 tgtttcattt ctacatcgct gaaagccggg gatagcacgg aacctgtatc tttatggtcc
    83041 atttcacaat gcttgatttt cttctgggct ttttctgtta gcgctacata cacttcccgg
    83101 ttgttctgag gatttctctg acgcgaaaca tagccatttg cttccaatac cttcagatga
    83161 cgagtaactg ctccttgatc aatctgcaac ttttcttgca aactgctttg tagcaatgga
    83221 ttttcttctt tcagtctcat catgatctcg tatctagtaa gacttatacc gatattttct
    83281 tcaaagatct ggacgatttt ttgatcggct aatttgattt gatataaaag gtgactaatc
    83341 tcttctaaag acataatttc ctcctttcta ataattgact cgtcaacgat tgacttgtca
    83401 ataatagaat aaaaaaagaa aaaagtcaaa gaatcagctg tgtaataaaa aaaacgctct
    83461 caatagaaaa gtatagagaa aagaaatttt ttgtagaatg aacggaaaaa atgataaaga
    83521 aagcacaacg ctaaaaccaa gattattgat tcttatcaaa ctatagaaga tagctcttct
    83581 gcagtagata attttacacc gccaaaaatt tccgaaatcg ccttttgcaa gaatcccgtc
    83641 gaatattaga aattggatca gtatgcttaa acagtaataa aaaagttatg acaagatgtt
    83701 gtcacaacct tttttgagta aacggtgttc aaaaacttgc atctgcggta ataagttcaa
    83761 ccaaacaaaa aacatgaaaa tctgtttttg tttggctgtt cttactactt gatgcagggc
    83821 agctttttca ctacctcttt ttaataacca taaaatccta ttccttcata tctccagccc
    83881 atcggtgtta gccaatctct ttccttagca ctcaaggtat agtgatgggt accagttttt
    83941 tcatttggat taaatagtcg ataaattggc ttggaaccac cagaataaaa acttagacct
    84001 tcataacgcc aaccgatttt tgttaaagag ttgatctcag attgtgccat tgtgtaatga
    84061 tggtctccac tgtaaggatt gtataaacgg tagacaggtt gtccgctgtt tggtgcttgc
    84121 caagcaatcc cttcatattc ccagcctaca gttggcagat aatttttttc tccggcattc
    84181 aatgtatata aatgttctcc tgtatgacgg ttatacagac gatacatcgg agaagttgaa
    84241 gttggtgctg tatcatactg tgtcagatta taggtttcga ttacattgtt caatgtagaa
    84301 ccataattag gcgcagtggc ataacgacct gttagccaag ccgtagcatc tttgtaagag
    84361 ttcgtattgc ttttccatgc accggaatag tagtaaacgc ctggctgaaa agaagtcgtc
    84421 ttcaataccg ttacgttatc ttgcaatgat tctttgtacg aaggatattt tctaaaagcg
    84481 gcattcaccg taatccattg cccattcaca tattccgaag taggcatcgt aacagattgg
    84541 ccattatagc ttcctttaat cccaaataga ttgtaattag gggcagaagc caaagtactg
    84601 ttcccccagc cactttcaac gatggcttga gcaatcatga ctgatgcata taagtcattg
    84661 gcacttgcca aactttgtgc agttgaggca atactatcaa tgaacgcttg ttgagaatta
    84721 gcagatgagc gagcataaaa agcatagcca gtatagtttt cgaattcaga caaatctgct
    84781 tgatgggtat gtgtcaatgt ttgcccatct gtcaattggt tcgtgatttc ttctgcattc
    84841 tctggattgt tctgagcttc tgctgatgta ctgtcttcgg tttgtgtttg ttctgttgtt
    84901 tcagttgttg gttcttcggt tgaaattgta ttttctgaga cagtagctga ctgcaaagta
    84961 ctttctgtat cgttttcaat tcctgtttct gaagaactcg atgtctgagt tgcgacagtt
    85021 tctgtcgatt cttcagctag cactgttgtg ttggcaactg ctagatttcc taaaagaata
    85081 acgctaaata ataaattctt tgctttcatc ttttttctcc tttgaattat gaaacttttc
    85141 ctaaataaca gtgtaactaa aaaagtaaaa gcaagtcaat gtccatattt aaataacatt
    85201 tgtttctttt taataaattt gctttttctg cataaaaaga cgtaaatgaa gaatattctt
    85261 ctccattcac gccttaaatt gatggtcgtt tgaataacta tttaacaagt aattctctct
    85321 ggatattatc cgttatggat tatacttcct gtgtcgtcgg acggataatc atgttgctga
    85381 cagacatccg gtctggcgtt tctatcgcaa atgctacagc agaagctata tcttcagatg
    85441 ttaatcccca ttctttttgc gcttcatgaa gttcaagagc agcctttttg tcgctgatgg
    85501 tttgatataa ttcagtttga acagctcctg gagagatgat cgtagatttg atgttatttt
    85561 gccgttgctc ttgacgtaat ccttccatga ttgcacggac agcaaatttt gttccgcaat
    85621 aaacggcgga atcaggataa acaacatgtc ccgccacaga atcagttgaa atgatatgcc
    85681 cagatttttg tttttccatg attggaagta cggcggaaat tccatttaac acacccatga
    85741 tgttgatatc aagcatattt tgccattcat cacggtgacc ttcaactaat ggagcggttg
    85801 gcatgattcc tgcattattg tacaatacat cgattcgacc gaacttttcc atcgctaaat
    85861 cgataactgc ttggacttgt gcaaaatctc ttacatctgc tgtttgaata tatagctcag
    85921 cttctggtaa agattctttt attgctttta ggcgatcttc tcggcgtgca gctataacta
    85981 gtttagcccc tttttctgct aatagcttcg ttgttgcttc accgattccg cttgaagcgc
    86041 ccatgatgac aatcactttt tctgataaat cattcattct attctcctcc tgttttgaaa
    86101 aatctcttgc ttatactcac tatctcttat ttcatcttac tgttcaaata atccgttcga
    86161 caggtttgac gattttggca gggattcctg caacgatggt attgtctggg acatctttcg
    86221 taacagttgc attcgctgca acaatggcat tctcgccaat cgttacgcct ggcagaatag
    86281 ttgctcctgc tccgatccaa gcatttttct tgatgtggat tggctttact gacaagcctc
    86341 ttcgttcttt tggatcggtt agatggttca ccgtgatgag gttgacacga ggaccaatca
    86401 atactgaatc ttctaaacag atgccaccta agtcaacgaa catcacttga cgattgataa
    86461 agacattttt ccctatacta atatgtttgc cgaaatctgt ataaaaaggc agcagaacag
    86521 tcaccgtatc atctactttg tcactaatga tattttctag ccgtttgcgg atatctgctg
    86581 gttcatggta cccagtattc agcgctgcta aaggctcttc gttttccgct tggatctgat
    86641 ggatcacttc aaagagcgga tccgttactc gaatctcttt attgacgatt tgtttttcga
    86701 tgaggcttgt cattttgctc cctcctttta tccttacttt ataacggacg gcttatgatg
    86761 tctaatactt ataaaacata cttaactatt ccttttaact atacttagtg gtatgctttt
    86821 ttaaaaacag gagggaaaaa atggatattc gtatactgac gtatttttta gcagtagcta
    86881 gagaaaaaaa tatcagccga gcagcaaaat ctctgcatat cacgcaacct actctctcaa
    86941 aacaactgaa agatttagaa gaagaacttg gtgtgacact tttcactcga ggctcccgag
    87001 agatacagtt gacggattct ggtcgatatc tttattcaaa aggaaaagaa atcttgtcgt
    87061 tggtagaaaa aacggcgaac aatttaacaa atgacgcaat catctctgga gaaatctaca
    87121 ttggcggagg cgaaactaaa gcaatctctt tcatttctga tagccttcat tcgttgatca
    87181 aggcgcatcc tgatatccag tttcatttat atagcgggaa tgcagatgat atcatagaca
    87241 aactggatag cggattactt gattttggac tcgtaatcga accgacaaac aaacaaaaat
    87301 accagtcatt tcgactgcca gcccaagatc gttggggact tttgatacat cggaatcatc
    87361 ctttagcaaa gcaaacagtc atccatccgc aggaactgaa aactgttcct ttgatcattt
    87421 cccggcaaac gtcagtggac agtcaactag ctgaatggct aggtttcagc atagatcagt
    87481 tatcgatcgt cggaacatat aacttattgt acaatgcttc tttgatggtc gataacggga
    87541 cttttggtgc attagctcta gatgggatca tcaatactta tgggacggaa aaagtattca
    87601 tcccactcga tccgccatta caagcttcac tgaatctcat ttggaaaaaa gaccagcctc
    87661 tttctcctgc tgctcgtaaa tttttagatg tcctaacgga gaaatacagt taagtagagt
    87721 ttttttcctt cgctttcagc tttttaacaa cgaataagtt aagcaaaaga tccaatgatt
    87781 aaataacata agtttcttaa tttgttcctt ccttttattt ctgataattc cagtaaatta
    87841 ctataattat aaaaaaagaa ttgacaaaac ataactgtct atataaaatt gattacgtta
    87901 acaataattc gtttcatgtg actagatcat actaggcatg aaaaatctct gaggaacatg
    87961 gtttccctag gaggtttttc gtgtctattt ttgtttggcc gcaatcaact ggtctagcaa
    88021 acgtgaaaac caaatcttca aaaagggtgc gcgcatgaaa atcaaaaaga tctttaatca
    88081 aaatgcagta ttggtagatg acggtggaca ggaaaaagta gctattggaa aagggattgg
    88141 atttgacaga aaaagaaatg atttgatttt tgatcgtgat gtcgaacgga tatttgtcat
    88201 ggaaccagaa ggtcaaatca agttgcaaaa tttacttaat cagattgatg aacgcttttt
    88261 atttgcagca gaaacgatca ttgatcatgc ggaaactgtt ttgatggaaa agttgaatga
    88321 acatgtattg atcgctttga ccgaccacat tgctttttct gcggagaaca ttaataacgg
    88381 tatcgtcatc cgcaacaaac ttttaagaga aatcgaagtg ctttacagtg atgaattcag
    88441 tattgctcaa tgggcagtag agtatctgac aaaagagctt gggattccat atacttatga
    88501 cgaagcagga tatatcgcaa tccatattca cagcggacga agcggtcgga acaataacca
    88561 tcgcagtatc cgtgaagtga cgattgtatc tgacatcatc catttagtgg aatcagaatt
    88621 ggaaacagat atccattcag aaccattttc actgaattat tcaagactgg tgaatcattt
    88681 acgactgctt ctacaacgaa cccatgcgca acaatatgct gttttagaca cggaaatcgt
    88741 agaaatggtc aaacgaaaat acccagaaag ctataagatt tctaaaaaaa tccgtgtgtt
    88801 gctgaccaaa gaataccagc tcgcgatcac gaaagaagaa ctgggttact tggccatcca
    88861 tatcgagcgt ttaagaagcg caatcgtaca aacaaatgtt aacaatcatg aggaggaaaa
    88921 aaattgaaag catatctaca acgaatggga cgttcccttc aacttccagt tgcggtctta
    88981 cctgctgctg ctttactagt agggatcgga aactggtggg catcttatag taacgacatt
    89041 gtcgctcatt ttttacaagc tggcggtaac gcagttttag gtcaattacc tttgctgttt
    89101 gccgttgggt tagcactagg gatgtcagtg gacaaatcag gtgctgctgc cttggcaggt
    89161 ttggtcgcat ttgaagttcc agtaaatgtt ttaaaaactg attcagtagc tactttattg
    89221 aatatcaaac cagaatcagt tgatccatct tttgctcaga tcagtaacgt atttattggt
    89281 attattgccg gattgattgc ggcagctctt tataatcgtt tccacgaagc aaaattaccg
    89341 atggctttat ctttctttag cggcaagcgt ctagtgccaa tcttggctgc ctttgtcatg
    89401 ttgctgatca gtgcagtgct actgctcgta tggcctccgg tttactctgc tttagtttct
    89461 tttgctaaat tcattttgag tttaggctgg ggtggtgcag gtctttatgg cttcttcaac
    89521 cgtttactga tccctacagg attgcatcaa gcaatgaact ccgtgttctg gtttgacgta
    89581 gcaggaatca atgatattgg taaatttttg gcttctgaag gaacaaaagg cgtaacagga
    89641 atgtatcaag ctggattttt cccaatcatg atgttcgggc ttccagcagg agcatatgct
    89701 atttacagaa atgcacgtcc agaaaacaaa gcaaaaacag cttccttgat gttagcagca
    89761 gcttttgctt cattctttac tggtgtaaca gaaccacttg aattctcatt tatgttcgtt
    89821 gcttggccat tatatgtctt gcatgcaatt ttcactggga tttctttagc agtgagtgca
    89881 ttcttccatt ggacagcagg atttgccttt agtgccggat ttgtcgatta cttcctatct
    89941 ttgaaaaatc cgattgcgaa tcagccattg atgttgatcg tccaaggatt agtaacagca
    90001 gtgatttact actttggctt taactttgct atcaaaaaat tccatctgat gactcctggc
    90061 cgcgaggaag cagatctttc agatgacgat actgcaacga ctaattcaga caataaatat
    90121 gcggcacaag caagcaaaat ctacgctgca ttaggcggag ccgacaatgt aacttcgatc
    90181 gataactgta ctacacgcct tcgtttgcaa gtcaaagata caggcctgat cgatcaaaat
    90241 aaaatcaaag ccactggcgt acctggtatg aagatcatcg acggaaaaaa tgcgcaagtc
    90301 atcgtaggta cagaagtaca attcgttgca gatgagatgg caaaactaca tggtggtgct
    90361 gcaacacgac ctgcacaaac aaacaccgtg gttaaaacag aaacatttgc cggtggaacg
    90421 atcgaacaag atatttacgc tatcgcaaat gggaaactga ttccaatcac tgaagtttca
    90481 gatgatgtat tcgcggaaaa aatgatgggt gacggctatg ctgtattacc agaaaatgga
    90541 gaaatcttct ctccaatcgc tggtacgatc acaaacattt tcccaacgaa acatgctgtc
    90601 ggaatccaaa cagatgctgg tatcgaagtc ttgcttcata tgggcatcaa cactgttgac
    90661 ttaaaaggcg aaccattcac tttatatgta aaagaaggtc aaaaagtcgc aagaggtcaa
    90721 ttgattgctt tagttgatct tgccgctatt caatctgcag gcaaaaacac ggatatggtc
    90781 gttgtattca caaatggcga caaagtccaa agcttagaaa tcgaacccgc acgtgatgta
    90841 aaagcaaatg ataaaatcgg ctctgtttcc aacaaagcct gagccatcgt cttccccaga
    90901 cttttttatc gataaacaaa caggagctga gacaaaaatc ttgtctcagc tcctttttcc
    90961 gaataaaaac ggcgttctcc tgccaactcc gcggtaataa gtccagccaa acgtaacata
    91021 tgaagagcta ttttttattt gactcttctt attacttgat gcagaacagc ttttttacaa
    91081 cctctgataa acggtgttca aaaaccagtt tatcggtatg aagtcaaatt tatgcaaaaa
    91141 tgtggaaagc cattttcaca aaatttttct tcatactcaa aactaatcgg ctttttcaca
    91201 acctctttat acattattcc tgatccaata tttcttttaa tgctgcttca agagaagtta
    91261 atggttttcc caatactttt tctaaatcat cagaggaaat agctaactga tcctttttaa
    91321 tatcatgttg gatcgctaaa aacatgtcag ctgcttcttg agggaatccg gcttctttta
    91381 gattttcgac aaacgctgca tcacttgctt caataatttc taacttttta cctgtcgcac
    91441 gctctaatgc cttggctaat tcttcatagt cagttagatt gccggataat tctaagattt
    91501 ctggagagtc actttctact agtacttttg ctgcagcttc tgcatattca cgtttcaatg
    91561 cccaacctgt ttttccattt cctgcagcat aaacgaattg accagttttt aaagcctgcc
    91621 caatgatagg taattcattc tctacatacc aattattccg taaaaatgta tgggaaatac
    91681 ctgaatcctt aatcattttt tcagtgaatt ggtgatctgg cgctaataca ctgatcgagt
    91741 gatcggcatc tgcaaaactt gtataagcga tataagatac cccagctgct tgtgctgcct
    91801 tcactacatt cttatgttcg gcttgacgat ttcctggaac gccagagaca aaaagcaatc
    91861 gatctattcc tttcaacgct tctttcattg agtctaaatc atcataatca ccaatacgta
    91921 tattaaatcc agcttctttc agtgcttctc ctttttcttc actacgtact agtacataga
    91981 tttcattttg tggaaccatc ttttttaaga attccagcgc ataaccacca aaacctccag
    92041 ttgctcctgt tactaaataa tgcatatttg ccactcccta ttctttttat ttgttaagat
    92101 ttacagctgt acatttataa attacacctt tatcataaag agtgtggtaa gataagtcaa
    92161 gcaaaaaaaa tgaaaggatg acaactgatg aagtattctc tgcaatttag tgatgcaatc
    92221 catgtacttg cctatattga aatgtttcaa gatacccgat cactttctag tgagatgatt
    92281 gccagtagta tcgaaacaaa tgcagcaaat gtacgtaaaa tcatgagtca gctcaaaaaa
    92341 tccggtttga tctttacaaa aaccggaaaa ccgcagcctt cccttgccaa aagtccagat
    92401 cagatttctt tactagatgt ctatcgcagc atcgaaggta atacacagct tatccaagtc
    92461 gatccaaaaa caaatccaaa ttgcgtcgtt ggtgcgaata tccaagaagc tttagaagaa
    92521 agctacgctc ggctgcagaa aaaggcagaa gaagaaatgg ctaagatcac acttgatagt
    92581 ctgatacata aaatagccgt tttggaaaaa gaaaaaagac cagaaaacac aggcctcgta
    92641 gagagatttt tataattctc tctactgtgc ctgcattttt ctgatcggaa tcgtctacat
    92701 aaattctttt attctccggg ggacaaaagc cttgtcatgc ccctttttcc tctctaatgc
    92761 tcaggtcaaa gcgctgaagt catgacgtct tgataaacgg tgttcaagta gctgaccctc
    92821 ggcattagtt ctgaaaaatg caaaatatgg aaagctattt cccatttttc ctctctaatg
    92881 ctcaggtcaa agcgctactt tcacgacctc tatattatca tggtttattg actaccggta
    92941 tccagatttc tcccatatat ttcccgttgg taactcccat ttcgactaca gcatttggac
    93001 ccccaacata ggcgtaatct tctacttctc ttaaaacatg cccaaaggcc gtattcgtca
    93061 aatcatttct taattcttca ggcgattctg ctaaagcgat tacaacaaga tacgttcctt
    93121 ttgggaatgg gatgattcgg gtagtgtttg gaacatcctg actcgtttga acaccgacat
    93181 agtacatcat tttcccgtta tagggttcgt tgactgtaaa gaaataatga ttttcagcag
    93241 cttgtttcaa tgcatctatt gttccattac cgataacttt ttgctcaaat gcttgtttct
    93301 ctgcagccaa accgacaaaa tccgtattgc tactcttcaa ttccacacca atacccgtca
    93361 ccgtaaaatc tggtttttct tcgatcctat actttgccat ttctcccacc ctttctatta
    93421 tattaagttc atcttacata aaattaaagg gaaatgacac gattacgctc ttttttctag
    93481 ggatattttt attttttaac tatttttttg ctttcactgc aatccaaatc tcactgtaaa
    93541 cattactgaa atcctctccc cattttgtaa aagagatctc gggagcttcg actaactcat
    93601 aatctgaaga aggaagccat tctgcataga ttttccccca agtatcttgt aaagtttggg
    93661 gaaatggccc tttattagga aaaatggccc aagtgtgttc ttctatagca agcatttcta
    93721 aatcagcgta cggattttct tttgtcgtag caaagccaat catgtgcatc aaactgccct
    93781 tttcttccaa gcgggctcca tcaaatccat aagaaacgtt gattacttga tttggatata
    93841 aatctcctaa cttatgcatc tcttcccttt gagtctccgt gatcgtctgc gctaactttt
    93901 gtatttcttg attgactcct tcaaatttga caggaacttt tttcgccaca cctgccacat
    93961 aaaactgttc tttcttttcg atacgaaatt ccatcgattt tcctcctctg acatcaataa
    94021 aaaatgtcaa gcgtggaaaa gatttttgta tgccgtatct gctgatttct gaaggcagat
    94081 atcctgacca atcacgaaaa gctcttgaaa aaccttcgac tgtttcatat ccatatctaa
    94141 acgccgtttc tgtcactctt gatccatcta ggagatcgcg attagccaaa gccaatctac
    94201 ggtttttgat atagtccatt agcgacatcc ctgcaataaa cgtaaagatg cgttttaatt
    94261 gatattcaga gattcctgta ttttcggcta ttattttata ggaaagtcct tctgtcaaat
    94321 gttcttcgat gtaatcgatc aattggttca gatctttaag catatttatc ttcctccttg
    94381 cttgcctttt tatcatatta tcaaagaaag tcaattactt gatgaatcag gaaccaattt
    94441 agtcagatgt agaaaatgtt gtatggatct aaagaaaatt ctcaagcagc gtttcgtaac
    94501 ggataattgg tattatctgc ctatctatgt tttaccttta gaaaaataaa ttttggggaa
    94561 gacacattct aagtaaacaa agcggtaaaa atatctttta ttcccttagt taatccgctt
    94621 actacctact gtacaaagca aattgttgtt caaactgctg atcagaacgc tgcttggatt
    94681 tttctttgcg atacatcata cctcttttat caattggaac aattatttat ttctaacaaa
    94741 atcacttcat ttttgtcaga taaataaaaa acaaaaaaag ttccatcttt aaaacacgct
    94801 attcttttac tttttctcac attctctaag aaaagaaaag gagaatgaat ttttgacaat
    94861 tcgagcaaaa gtgattatca aatatgtaaa atcagctact tttttcttaa acgtttcttt
    94921 atactaaata taaataagtg tttcatgaaa ggagaactag atgaataatt ggcttgagta
    94981 ttttcctgaa aacgttttgg aacgcggtta cagctatcat ctgcacggtt ttgtccgtca
    95041 tttgaactat acaagcaagt acttgtccgc aacagtttct ggcacggaag attataaggt
    95101 agtgatcact tgggatgaaa agaccaacat gacttgtgat tgtctatatg ccatagaagg
    95161 aaaaaaatgc aaacacatgg ctgctgtctt attcgcttac gaagaacgtc caataaaaaa
    95221 atccaactac tcactttccg aactctcgtc ccttgtttcc tccgctagtt cctctcttgt
    95281 acgggagctt ttaacagaga ttcttataga acatccgcaa tttatcgaac gcttcaaagt
    95341 taagatgcca tttcatgcaa taaattattc agataaatta acaactatca tccataaata
    95401 cgatcatatt atcaagaaaa acaaaaacag gaaaacagcg aagttcatca tggagatgcg
    95461 aaagttcatc caagaagcag ttgaatcgct cattcagcaa aatgcctatc ttcccgcatt
    95521 cgaattgatc aatgaagtga ttgctactct cgaaacattc tattgggagc ctgaggatga
    95581 acgaaccctt cttctgatag aggactgtta ttatttatgg aaagaattat tagcagaagc
    95641 acctcatgca gaaaaaaggc aaatgttctc ttggttcgtc tgccaagtcg atcatactga
    95701 cgcctcttat tcaaaacgct actccataaa aatcctgaaa gaagactttc gggaaaaaga
    95761 attttctaac caaaagaaaa aaatagataa aaaaactaaa gaaacggtaa agaaagacga
    95821 tttcaatgaa aaatagcaag taaacgataa caaccatcct aaatccacaa gaaatacagc
    95881 agaccttgct ttaaaaacac gaatcatgca aaggatgaag taaagaagac ttaacgcgta
    95941 cccaatatta gtcatttgac tattaggtac gcgttttgtt ttataagtca tgacaaattt
    96001 ccttcgttgc tgggtagatt ttccggcatt gttgatagat tttatgatac ttttctacat
    96061 tttgtaagag aggttccact gcatctgtat attggataaa attctgacaa caactttcag
    96121 gtgtgtcgaa ccactctaat ctttaaagat aaatattaaa ataacgatta ataatattaa
    96181 cagtctttat ttttcaccac caaaaaccta tctttgcata tactaaatag acgtatatac
    96241 acagataggt ttgtcttgtg aaaaataatg attatcctta ccaaaaaatg tttgtttttc
    96301 tacatgttcg tacttatcaa aaaatatgat ccttattgaa attactggct atttatattc
    96361 caacgacttc ttgtgttaat ttttgttatc tcatagtaaa ttatgtttca ttttcactta
    96421 atttagttgt cacgtgttcg tcaattcgta aaaacggtaa atatataaac acacttgcgg
    96481 ctataattaa tatttgtaaa acagctgctc gccagtctcc ggctgttgct aaaaatcccg
    96541 atataactgg tggcgtagtc caaggaattt gcactactac atgattaatt aatcccacag
    96601 cagttgcaaa atatgctact gtcaaagaaa aaatcggtgc aagcacaaag ggaataatca
    96661 gactgatatt aaatacaata ggcaatccaa aaataatagg ttcgcttata ttgaatatag
    96721 cgggagttac cgataattta gcaaagtcct tataatcttt tctacgactg aagataaata
    96781 ttgcaatcaa taaagcaatc gtatttcccg atccacccat taccgcaaag gtatctttaa
    96841 aggccatatt gataatatgt ggaatttgct ctttgtttgc ataagctgcc atattttctt
    96901 gcatattctg aatcaaaaac ggatctaaca atgaacctga tattactgct tgatggatac
    96961 caaatccaaa aaatagatta gcaatagatg taattaacaa aaatcctggt aaaccagttg
    97021 taattttact taatggctct gtaactatcg tggtaattag cttatttata tccatattaa
    97081 acaattgaat gattataaat gacaataaag caaacgaggt aatcgtaata atgattggga
    97141 ttaatacatt aaaagacttt aaaacagcgg gaggaatatt tccggatagc tgaatctgta
    97201 gtttcttatt attagaaagt ttaataaata attctgtagc cgctaatcca acaaatatac
    97261 ctacaaacat tcctgaagct cctgtatagg atataggtat cacacccgtc acttcaacag
    97321 ctttatccgc attttcagga gtaaacatca tctgcatagg tgttaataca acaaatgtcg
    97381 aaatagcaac taataccgct gcaatatgat ttgtataatt tctgcttgca cacatatgat
    97441 aagatactgc tgctacaact aataatgtag ttatgcttaa tgtaccattg gcaattgaag
    97501 taccaatttg ttgtaacgtg gtcaatgtac tagtatcgac aatttccccc atgaatcctg
    97561 ttggttctaa gatcactgaa ttaataagtg tcacaaatcc tgctaacatc ataaatggca
    97621 taaatgtagc aaacgcatct cgcaaagttc ttaaatggat ctgattcccc aacttagtcg
    97681 caactatacc aaatttttca aatacaatgt ccttcctgct acttttgccc atattttttc
    97741 tcctttatgc ttattgtaat cgattacttt ttccacccaa ataatacatc acttatcaaa
    97801 aaaagtaaat acttttaatt aaatatatat atctttttta gtataaaaaa ataagctctg
    97861 aaaaaataat tttcccgagc ttatttttca acaaaaacag cttcaaaaac aaagtcttga
    97921 tataaatgtc tcgataccga atactcgaaa ggtttaccag acgatagagc aacaactttg
    97981 tctatctcaa tcataaattc acctggatct atttttaata tttttgcgtc aaattcattc
    98041 gcagtatctc ctttgatacg tatgtgcgaa gtctttattt ccagacccag ttcatttgtg
    98101 atataagcat atacagattt ctttaaatgt tttggttcca agcctggtat gactgctaat
    98161 ggcatgaatg tttgctcaat cgagtatggt tgacaatcaa taaaacggct tcgtacaata
    98221 ttatatacat agtcttttac actgatactt aatttatcag ctactttttt cgatggaagt
    98281 tcaattgaga aagtatggat ttctgaatct acgtgttctt caccaaccac gctaaacaaa
    98341 ccttcgtttg gaccaagaac tcgtgagtta tcaattggtg ttctgacgac ttcagtccca
    98401 tacccacttc tacttcgcaa aactccttcg gaaacaagta agtctacgcc tttctttact
    98461 gttaacttgc ttgtatgata aataactgcc aattcatctc ctgtaggaag tttctcacca
    98521 attttatact ctccatttac aatttttttc tttatatcta agtaaatttc catatacttc
    98581 gcaatttttt tcaatggtga ccctccaatc aaaaacatat cttcatctat actttaacat
    98641 aaataaaccg ataaaatcca catcaaaatt atacacacaa taaaaaagat atatatattt
    98701 aaacaaaact atttacttta agttgtaagc ggtgttatca ttaagtggaa acaggaggta
    98761 aaaaaattat gacaactatg aaaaagctaa cttttccaga tgatttttgg tggggttccg
    98821 cttggtcagc tgagcaagca gaaggaaaag gagaaacagg aaaagcagag actatctggg
    98881 atcgctggtt taaagaacaa ccttaccggt tttatcaacg aatcgattcc tctattacaa
    98941 ccgatcacat ccatcaatat aaagaagata tagaactaat gaaaaaaact gggcataact
    99001 cctttcgcgt ttctatttct tgggcacgaa tgtttccaaa tggcggtacc ggaaaagtaa
    99061 atcccaaagc catttctttc tatcgaaaat tattttccga aatgaataat aacggaatca
    99121 aagtatttgc caacttatat cattttgaca tgcctgctac tcttcaagat aaaggaggat
    99181 gggaatcacg tgaagtagtt gatgcttatg ttcattacgc tgaaacttgt tttaaagaat
    99241 ttggtgactt agtttgtcat tggtttacct tcaatgaacc acttgggcct attttaggta
    99301 cttatcttga agattttcat tatccaaacc tcattgactt taaacgcgga gcgcaagcag
    99361 cattcttcac tatacttgca cacgcaaaag caatacaagt atttaaagaa ctagctcttc
    99421 ctagtaaaat aggcgttatt ctaaatttga gtcctacttt tcctcgtagt caaaatcctg
    99481 ctgatgtgaa agcagcagaa atcgctgatt tattttatac gcggagcttt ttagatccta
    99541 tggttaaagg gaatttttct aaaaagctta tcctgttatt acaagaatat aatcagcttc
    99601 ctgaagatta tacgaaagaa gatcttgtat gtatctacga aaataccgct caaattcttg
    99661 gactaaacta ttacgagcca cgtcgcgtca aatctcgttc ttctatggtg gatacatcta
    99721 gtccattttt accagagtgg tttttcgaac cacatatcat gcctggacga cgaatgaacg
    99781 aataccgggg atgggaaatt tacgaaaaag gaatttatga tttgtgcatg gatatcaaga
    99841 accattatgg aaacatcgaa gcatttatct cggagaacgg aatgggcgtt gcggatgaag
    99901 aacgtttcat ggatgataca gggcaaataa ttgatgatta tcggattgag tatatcaaag
    99961 atcatcttgc ttacttatgg aaggcaataa atgaaggatg taacattaag gggtatcatc
   100021 tttggacatt tattgattgc tggtcatgga tcaacgccta taaaaaccga tatgggctgg
   100081 tttcactcga ccttactact caaaaaagaa caattaaaaa aagtggcgaa ttttacaagc
   100141 aattaagtga tacaaatgga tttagatacg atgtagactt gttagttgaa taatattcta
   100201 aaattccact tgaagtgaac acattagaaa acaagaataa tgagaaatac caataacaaa
   100261 tactttttct tcatacttca tttatacttg tcagtataag agactgtgac aaatgtagtg
   100321 atcctcagaa gttaggtctg gaaatctaac ttgagaagat ttttttaaac tacgtccagt
   100381 cttttttatt tgtttaaaat tgaagttgac aagtcttcat taaaaattta gaatattcac
   100441 aagtttgacg acaattatga aaatttatgt cgtgctaaag gagttttgtt attggatgaa
   100501 aagttagata taaaaactgc gatcaaagac acgttaccta ccgtttttgg ttatatcggt
   100561 attggacttg catttggtat cgttgggaaa gctgccgggt ttcatccgct ggtcgtcacg
   100621 ttgatgtccc tgctgatcta tgctggttct gcccaattta tcacggtcag catgcttgct
   100681 agccatagtc cactgctctc catcgttctc tcgacctttc tagtcaattc ccgaatgatt
   100741 ctgatgagta tgacgattgc tccttatttc aagaaaaatc ggctgcttca aaatctgctg
   100801 attggcacat tgctgacaga tgaaagtttc gcactgggaa tgaataaatt gaactatact
   100861 ggacaaaagt taaactttcg ttggatgaat acagctaatt ggatttctta tttgacgtgg
   100921 gtgggttctt ctcttgttgg cgcactttta gggaatttta ttactgatcc gaaaaagttt
   100981 ggtttggatt tcgccatcgt cgctatgttt atcgggttac tttatcttca agtcatttct
   101041 gatagaaaca cctctaaacg attacagttg atcctgattg gtctcacttt gattctggta
   101101 tatgtcggac tgatttttat cccaagtaac ttagtgattt tagttgtaac actgattggg
   101161 tgcggattgg gggtgtggat caaacatgcc ttcttttgag tttacattgc tgactatttt
   101221 aggttgtact ttagcaactt ggctttctag gatcctacca tttgtcttac tgaaaaaatt
   101281 cgatttgccg caaccgttgc ttgagtattt aagttttgtc ccgatcgtca ttatgtctgc
   101341 tttatggttc agcagtctat ttacccaaaa tatcggacat ctgccgcaga tcaatctcga
   101401 aaatgctttg gcttcagttc ctacactttt agctgctatt ctttcaaaaa gcttattggt
   101461 gatcgtcttg gtaggaattc tttccctttc gttgattcgc ttattataaa taaaaaaaca
   101521 agagcttatg gcaaattact gtcatgcgct cttgttttta tcaaagtcaa ataagaaaaa
   101581 aatcggcgta ttcttgctta tccgttgaac ggaccactaa caacgacttt tcctaatata
   101641 tgtcctgttt ctacgtcttt ggttgcttgt ttcaagttct tcgcattcat cccatctgaa
   101701 tagaccttgc tcaatgtact gcggataatc ccttcatttg ctaaagcagc aatgtgcgct
   101761 aaagcttctc cttgcgtttc gatttcatag ttatagtctg ttttagcgaa catatactcc
   101821 cagtcgaagc tgatagattg gtttttccaa acacctatat ctaacggctc tttgatccct
   101881 acgatcgttc ccacatgtcc aaatggtcgg acaaggtgtt tgatttgatc aaagtagcgg
   101941 gtaatatcga ataatacagc gacatactct acttgatcga ttcctaattc acgaaaactt
   102001 ttacttaagt cgtgatgata atcgattgga tagtctacac ctgttttttt cagccattca
   102061 aaattcttcg gacttgcagt cgcgtagact tctaggccag cccaatgcgc tagttgattc
   102121 aaaatcgaac cgacgccccc agctccgttg atcactaaga tttttttccc gcggttggca
   102181 ttttcttctg gagtcagacc aaatttttca aataacaatt cataagcggt caatgaggtc
   102241 aacggcaagg ctgcggcttc ttcatctgaa agattttttg gtgcaagagc gacaatacgt
   102301 tcgtcaacca gttggtattc ttgattgctt cctgctcttg tcgttgtacc tgcgtaaaaa
   102361 acgcgatcgc cgacagaaaa tttttgcact tcatcaccta cagcaacaac tttcccgact
   102421 ccatcaaacc ctaagatacg taaagcattt cttatcccgt tatcttggcg aagtttcgta
   102481 tcgacaggat taacagatac tgcgttgact tttaccagaa gatcccgtga actgggtaca
   102541 ggtatctgtt ctttttcatc aataaagctt tttggatcat cgatcgacaa cccttcataa
   102601 aaaccgacta ccttcattaa ttccttttct gacatacgaa ttcctcctta gcttcatcaa
   102661 gttggagcat ccatacagtt ttcatttcaa tatatatagt atgctatttg ttccactttt
   102721 attcatcata attattctct tacttaaagt aaactatttg cacttttttg gttaaaaaag
   102781 aggttgcgac aagacttttg tcacaacctc ttttaaacgg tgttcaatca actgaccctc
   102841 ggtattcgct caaaaaacga caaaatatga ggagctattt ttgtttggct gttcttatta
   102901 cttgatgcag gacagctttt tcacgacctc taattcacgg tgttcaagca agaaatcatt
   102961 gttcactgaa aagcgttgga tgttcttttt caaaggtgtc taagatctct cgtacttcat
   103021 cagtagattt cgtattcatc aactgaactc gcaagtcatt tgctcctgga aatcctttga
   103081 tatagatttt aaagaaacga tgtagtcctg tgatggaacg cgggatgatt tctgaataat
   103141 gatcttgcag atctagttgc agacgaagta gtccgatcag ttctttttct gtatgttccc
   103201 tcggttcttt ttcaaatgca taaggattct tgaaaatccc ccggccaatc atgatgccat
   103261 ctacgccata tttttcggcc aattcttctc ctgtctggcg atctgggata tctccgttga
   103321 tcgtgatcag tgtttgcgga gcgatttggt cacgtaaagc aatgatttta gggatgactt
   103381 cccaatgtgc atctacttta ctcatctctt tacgcgtacg caaatggaca gaaagattgg
   103441 ctatatcttg atgaagtagg tgactgatcc attcttccat ctcagacatt tccgtatagc
   103501 cgatacgcgt cttgacgctg acaggcaaac cgccagcttt agccgcttca atcaattgtg
   103561 ccgctacttc tgggcgaagg atcaagccac tgccttttcc acgttctgct acattaggga
   103621 ctgggcagcc catgttgata tcgattcctt ggaagcccat ttctgccata gcaatgctca
   103681 tttctctaaa aaattctggc ttgtctcccc aaatatgggc aaccatcggc tgttcatctt
   103741 ctgtaaaggt caatcttcct cgtacactgt cttttccatc tggatgacag aaactgtctg
   103801 agtttgtaaa ctcagtaaag aagacatccg gtgctgctgc atgctttacg acatggcgaa
   103861 atacaacatc tgttacatct tccattggtg ctaaaacaaa aaaaggcttt ggcagctctt
   103921 tccaaaaatt agtagtcatt tatttgttac tctccattct atcaagcagt gaagtcgcaa
   103981 tctttctcaa aaacattgtc attatactag gaaacaaaaa aagaagcaaa gtgaacagct
   104041 taaaagatgt ttctgattga gcaaaaaaag actgtgacaa aaatcttatc acaattcctt
   104101 ttccggaata aatggtgttc aaaagcttgc atctgcggta ataagtccaa ccaaacgaaa
   104161 aataggagga gctatttttg tttggctgtt cttattactt gatgcagaac agctttttca
   104221 caacctctcc actaaacggt gttcaatcag ctgaccctcg gtattagctc aacaaacgac
   104281 aaaatatgag gaactatttt cccgtttgtt tctctaatac tcaggtcaaa acgctgattt
   104341 cacaacctct tttctaactt ctcaatcctc ttcctttatt gatcaaatac caagtaacgg
   104401 cgtacaaaac aacgatgaat agcacaagta cgatcatcga tgttgctact ggcacatcga
   104461 ttgttccaag gaatccgtaa cggaaaccga agatcatata aacgatcgga ttgactttcg
   104521 aaacagcttg ccaaaatggc ggcaacatag agatggcata gaaaacgcca cctagataag
   104581 ttaacggctg caagacaaat gtaggcacga tcgatacatc gtcataagac tgagcaaaaa
   104641 tcccgttgag cagtcctgct aacgaaaaca agattgccgt catcaataat gtaatgatga
   104701 ccatgaacca tgaatacaca tgaagtggta caaagaacaa ggaaatgatc gttacgagag
   104761 agccgacgag aatactgcga cccactccgc caatcacaaa gccccaaatg atcacatgcg
   104821 taggaacagg cgctaccaag atttcttcga tgtttttctg gaatttttga gagaagaagg
   104881 acgaagaaac gttggcatac gaactagtga tagcagacat cataatcaaa ccaggcacga
   104941 tgaattccat atatgaaaaa ccacccatgt caccgatccg accaccgatc atttttccga
   105001 aaataacaaa gtacaaggat gtcgtgatca caggcggaac cagtgtttgg acccagatac
   105061 gcaaatagcg gttcgtttcc ttgatagcta aactttttaa tgcagtaaaa taaagattaa
   105121 acatttttct cctccgtatg attattttct tctgtgattt tcaaaaacag ttcttctaaa
   105181 cgattcgact tattcctcat agaaagaact ttgattcctt gtcttgtcag ctgatcgaag
   105241 attccgttca ccccttgatt tcgttcaact tcgacagcga ttgtctgttc atcttcaaat
   105301 gtacaagcgt atccttcaat cacaggtttg gtctcatatg gcgctaaatc aaagataaat
   105361 gtttcaaatt gcagtttgga tagaagctct ttcatactag tattctcgat cagttcacct
   105421 gattggatga tcccgatgtt gcgacaaagc atttcagctt cttctaaata atgcgtcgtc
   105481 aaaatgatcg ttgtaccatt ttcgttcaat tctcggagaa actcccacat ctcgcgtctc
   105541 aattcaatat cgactcctgc tgttggttca tccaagatca gcaaacgtgg ttcatgcatc
   105601 aatgccctag caatcatcag tcttcgcttc attcccccgg aaagcatacg tgcacggaca
   105661 tttctctttt cccaaagatt ggactgcttc aaatattttt cgctgcgttt catcgcttct
   105721 ttgcgagaga caccgtagta gcctgcttga ttcacgacga tttgctggac cgtttcaaag
   105781 ggattgaaat tgaactcttg cgggactaat ccaatctgtt gctttgctcg gactagatcc
   105841 gtatccagat cataaccgaa gacattcact tttccagatg ttttattgac taaagaagta
   105901 atgattccga tcgttgtaga cttcccagct ccatttggtc ctaatagcgc atagaaatct
   105961 ccttctttca cggaaagatc gattcctcgc aatgcttcga ccccacttcc ataaaccttt
   106021 ttcaaattat ttatttcaag cgcatttgcc atttatttcc tatctcctta tagacatgat
   106081 tctttattgt atcatggaat acagcagatg aaaaaacaac ttggttccag cgaaaaatca
   106141 ggttgctggg ctcaggaaaa tctcctaatg aaagacatca atcggacgaa gtcagacaac
   106201 cttttcagaa aaaacaaatc gaagataaag gattactatt catatgtgca acaaaaggag
   106261 cgtgagacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcggaa
   106321 gcaaaagcca agatttttga tccaataaat actttcgatc acttcgccta tcccaataca
   106381 tgccactgcc gcttttcatc aaataacgcg gcttccgttt ttgcggtttc tactaaagtc
   106441 tctgggtaat ccaaaacttt cagcaaggca atcgcatttc gggtccttga aggtccttct
   106501 tttaatttga aatcaaaact gattcctttt ccttctgtta cttgttcttc aaagtggaca
   106561 ttctcacaat aattctttaa aatctctgtc aattcgatat catgtgtggc gacaaatgct
   106621 aaagatggat actccgcaag ccaccgaacg actgaagcgg aagaagcaat ccgttcgatc
   106681 gtatttgtcc cttttaaaat ctcatctacg aagcagtagc agcgttcttt ggaagccact
   106741 tggtccaaca aacgtttgat cgatttgatt tctgaaacaa aataactgtc gccttcaaat
   106801 aaatcatctt cgattgccat ggaagtcaac acatgtccag gttgcagggt aaactgttct
   106861 gcaatcgctg tttggatcgt ctgtgctaga atacagctga tggctatact tttgacatac
   106921 gtagattttc ctgatgcatt ggaacccgtg actaatgtat tcttctgcca gttgaccgga
   106981 ttcactaccg cttcttttaa caatggatga tagatatctt tcgctgtcac accgccctca
   107041 gtaaactctg gtcggcaagt gatgggcata taagtacggt aattcaatat tgcagcggct
   107101 acttctaatt ctcccagcaa ttcccacagc ttgatggctt cagttgaatg cttttctaat
   107161 ttagtgagaa cgaaatgata ggagataaat ggcagcatga acatgatgtt gacatattca
   107221 aaaatcaact ctgcttcact cccactcttc atacgaaatg aaaaacctaa tttagggatg
   107281 tctcttaatg gtttagtttg ctgtttcagc tcttcttgaa gtggtgtcgg cagttttgct
   107341 agctgattgg cggctgaaat cgttgaaacc aaataactca tgctattcag ctctgtttct
   107401 agtgtttgtt tcttcactag ataatagacc gtattgaata ctaacccacc gattgccaaa
   107461 tagattccta gtacttgtcc taaaagaagc aaacccaaac ccaccagcgg aagcaagcca
   107521 agaaaaataa ataaacctac gcgtccaatc tttttacttt ttccatccgc tagatattgt
   107581 tttgcaaaat tatgatcttt ttttcctaaa cgagcgaatt gatattggat tttttctctc
   107641 agttgaggat tttcctgata aaaagcaatc agtttttcta actgctgatc ttcaccaaaa
   107701 tcaaagctgc gtaaacgttg atacaacgct tctgaaccta cactagaata ggtactgttg
   107761 attccttcga atacttcgaa catatccagg tcataccaag taagatcatc gatttcgcta
   107821 tcccatgaac ggaacttctt ctccgtgagc catgcttcct tcaagctttc ttctttatca
   107881 aatctcggtt gataaggaat tttttcccat ttgctacgaa ctgtttcctt taatttcaaa
   107941 cgtgaaaaaa tgtctaaagc aactaataaa ataacagctg caataataat taaaacgata
   108001 aattctcttt gacccatatc cctctccgtt cctttatttg ttagctttag tatagcactg
   108061 ttgcgctatt tgaaaagagg gtaaaaaaac acctttcaaa ataaaaggtg tttttttctt
   108121 gtatattaca tatttatctc tcatttatca aaattgacaa ataatcatag ggaggaattg
   108181 ttgttaattc ttgtttattc tccagtgcat tgacaactgt cccaagggaa aggatagcct
   108241 caggtactat tttttcttgt tctgttggat tagctaagcg aagaacaaat ccttgttcat
   108301 gaaaataaga aggataaatc gatgatacaa ttaagtcttc aggtaattca atcaatgaaa
   108361 atttacgagg aacatcaagt tcattttgta atggccaaat cttgttatct aacctgtgaa
   108421 taaatacatt cagtttctgc ttttgataag aaatagattg ttctaaccgt ttttctgcct
   108481 gttttgccac tttgaactca ttaaatcttc cttcttctac attaaatcca aaagtgactt
   108541 tatactcacc tatctcttga gctagcggtg tttccatcat gacatgccct tcatttgtcg
   108601 tatctcctga agctcgccca ggtcgccaag caagattagg ttttccaagt tcccctgttg
   108661 ttgaaaataa ggttatgatt aattgatttt ctatacgttc atactctttt aaaccatctg
   108721 cataaaacgt aaaataatga tcattttctg ccacagagac actcttatcg aatatttcta
   108781 aattaacagg tttctctacc atagtttctg accaattcgg aggaatgaca tcaggggtat
   108841 tttcaataaa tccgttttga atttgtgcaa ttgatttttc agatttatct aaaacattaa
   108901 ttgctaagcg catacgatgc gagtaaacag tattatgaat tttgagtgtg ccttcaacga
   108961 tttgactttc tcccagactg aacgatattt cataagatat ttcttccatt tcgggttttt
   109021 cagataaacg atcttttaaa tctttaggaa gttgagcttt tccgtaaaca actaatgttt
   109081 cttgtaaaga atctttatat actttagctg tttctaattt tagagatagt tctgtatctc
   109141 cttctaatgg tgaataatca tacgtatcgc catcatttgc tgaatcgatc aaatgaacga
   109201 aatcaagata ttgtctatct ccaactatca aattcaattg cccatcttta aaagaaagtt
   109261 tatatttatt gttacttatc tcagttttgt ctatctcgat tgctgtttct aatttttcat
   109321 tatttttctc aaattcaaca acagtgtatc ctagtgctgg cacatttaca tttattttta
   109381 tgtcaagttc ataataagct ggttcatcaa aatattcgaa acctgtagca atcatccgat
   109441 aagcattttt ccgttctgga aaataaactt ctttttcaat gatattatag ggactacctt
   109501 tgaagtgtat tttctttgaa tcagctacta catgcacgat tttcgatcca ctataattct
   109561 cagtcgttgt gttgaaaaca aggacttcat tcgattttag ctttaatgca tcagccatcc
   109621 gttttacaat aaggttttcg attccgtcag ctatctcatt agcttctttg attcgatgga
   109681 aaatatcttc cgcaacatta tctgaaacac agccaccaat actatcatga gcctggtttt
   109741 gcaaaatctt tttccataac cgacgaagta ggcctttact gatatggata ccatttcttt
   109801 ctgcaatcag catgagcggc tcaactcgtt ttagaatttt ttgttccaat ttaaaatttt
   109861 ctattttcat ttttgttctt actgagccaa tagaacgatg aacacgagag taaaccggct
   109921 gacgaagttc acctttatat tcaggtaatt cttttttgtt tctgataact tctacataag
   109981 aaggataatc tgaaataata ttgtggaatt tactgtattt attcaacttc tctacgactt
   110041 gatcaaaatt taaaatcatt gacttttgat ctacacccga aggtactaaa atatctttgt
   110101 tttttccttg catatgaagc atttcaactg cttcatccaa cttttctttt gcaaattcag
   110161 gaatatcttt aattgcgtct aaggtcatca ttccagtcat ataaccaaat ggaaaattca
   110221 tggcataaac aaatttatct cccaatcctt tccagataaa ataaggagat ggaaccatcg
   110281 tttcaaagtt taatcctcgc caacacatga aattatcgat ttctacttga tgcaaaagtg
   110341 taggcaaatt cgcattgaac ccaaacgtgt caggcaaata ccctaccatc attggatctc
   110401 catatttaag gatcgtatca ctgattccaa tcattaagtt tcttaaaatt gattcagcat
   110461 ccactaataa ggcatctgtt tgtgcatacc acggtcccac gaatagttgt cctgttttca
   110521 tcagtcgttg gataacctta agcttttgcg gattgatctc caaatactca tcgacgattg
   110581 aagtttgtcc atctaaacaa aagtttactt tagggttcct ttccaattca tctagaactt
   110641 cagtaaagac ctgatcagac aatacgatgg catcttcatt tgtaaaatac cattctctgt
   110701 cccagtgcgt gtgttgaatt atatgtgcat ttaccatatc agattctcct actttccttc
   110761 ttctactgaa tttacttgtt gttctttttt atacttgatg gattttagtg cattgaccat
   110821 taacgctgta accactcccc caataacaat tgatactaaa tataaaggta tattcgtaac
   110881 aaaaggaatt gccataaagg ttgaaagcat tgtttcttga gtaacaccaa aaaatccatt
   110941 tagaccacat gctactgcag tgcccaccac gatgcttggt attactcgta aaggatcttt
   111001 cacggcaaac gggatcgtcc cttcagtaat ccccacaagg cccataatca tagctgtctt
   111061 tgcattatct cgttccgatt catcataaag ttttttgttt aaaattgttg ctaaaaacat
   111121 tccaaatggc ggaatagcaa ttcctaataa catggctgta ctaggtccaa agcttccgct
   111181 tgaaaaagaa gcaaccccaa aagcatatgc gattttattg ataggtcctc ccatatcaaa
   111241 cgccatcatt cctcctaaaa tagccgacat caaagcagca tttgctcctg acatgccttc
   111301 tagccaatta gtcagtcctg ttgtcattgc ttgaataggc gtagctagta cataccataa
   111361 tatgattcca acaactaatg tagtaacaaa aggaatcagc ataattgatt ttagactaat
   111421 aacttgcatc ggtactttta cttttttcaa tgcattagct aaatagccac aagctaatcc
   111481 agcaaccatt cctccaataa atcccatacc aagattttga cacatcatcc cagtgataaa
   111541 agctggtgct agaccgggac ggtcagcaat tgaatatgcg atataggctg aaatcatcgg
   111601 tacgataaac tgtaatcccg tctgaccaat cattcgcagg actccccaga atgtatccgt
   111661 ctggtcccaa acacctgtgc caccaaaaat gactgcaata gaagttagta accctgctgc
   111721 tacgacaagc gggatcatat aggaaacccc actttggaaa tgatttagaa tttctcttcc
   111781 ttgtttcttg aattccatta gtaactcccc cacgatatat tttttatttg ttaattaatg
   111841 caattgcttc atcaatcgtc tcttcaccat cttttactac ctctgaggtc cctactgtta
   111901 aaatcggttt accgtcaaag cgacctcgtt ctgaaacatt tgtatctact gcaaatatga
   111961 caacatctgc ctcggaaaca tccgaaattg aaagtttgtt ttctatcccc atagccccct
   112021 gtgtttctac tttaatatct aaccctttct tcttcgcaaa cttttctaaa ttagcttttg
   112081 ccatataagt atgggcaatc cctgcgatac atgctgttac tgctactatt tttgtcatat
   112141 gaaattcctc cttttaaaat gatagagctt ttaccaattc ttttttattt ctcgaatctt
   112201 ttattctttt aacaaactcg tcatccatca atcttccaga taattctgct aaaatacgta
   112261 aatgattagt acctttatca gtgtctttta ttgctaacaa aaagacgaga tcaactggtt
   112321 gatcatctaa tgcgccccat tcaacagacc gctttaactt ggctacagcc actgttgatt
   112381 caattactgc taggcttttg ccatgaggaa tggcgatatt tttcccaatt cctgtggtca
   112441 tatggttttc tctgtcaaat acgtcttttt gaaattgttt gtggtcagac acaaacccat
   112501 tagtctctaa caatttcgat aatttttcga ctacactttt tttatcagat gcatttaaat
   112561 ctatcactat attatttata ttgatttttt cactgatcat ttataagcct tctttcaata
   112621 tataaactaa tttttcaaac gacgaactcg tttttaaatt tgctaataac tcatgattcg
   112681 aagcgatttc attgaatgtt tcataaattt tattcaattc aggttttact ttttcattaa
   112741 gtgcaaaaaa gaaaacagaa tgaacaagtg tcccatccca atcaattcct tctggattaa
   112801 cgtagacaca gattactggc ttttttataa aatctacttc gatatgcggc atagcaaaat
   112861 cattcatcgc tgttgaagat agtttttctc ttttgattgc tccctctagt atcccttctt
   112921 tcgcgtaatt ttcttttacc aattttttgg taattatatt taaaacgttc acttgattat
   112981 cctttatttg gtgggtaaaa aagcaaaatc gtttatctaa taaatttaga aaagcatctt
   113041 ctgtttgttc atttaactgt agatactgtt ttacttttct gacatctgcc cctaacatca
   113101 aaggactaac aacaataaca ggaaaatttg tattttcaat cggaatcgtg cttataacaa
   113161 gttcatcagt gacttttcta tcttgtagtt cattgatgct tagtacatct tctatctcaa
   113221 ccatatctgc aaaaccgtta tttattcttt gctctaataa ttttgatgtt ccatatccgc
   113281 tactacaaac taatatcact ttcgttttgt caggtttgta acgatccaaa agtgattgaa
   113341 tatggagtgt tacgtaagcg atttcatctt cattaaaatg tatacagaat ctctcttcga
   113401 tttcctctaa taaatctaca cttatcataa atgacctttt aaaagaatat ttgattttgt
   113461 ccgtataagg gttatagata tttactccca atttgagtct tttaactgct gcattgagat
   113521 gtaatactag attattgatc aattcttcat caggataaaa ttcatttaat ttaattctta
   113581 ctaactcttg tagctcaaca cccatatcta aataggaaag cttcgtttga tctaagtcgt
   113641 gattcatagc atttttttca atcgaagtaa tgtgaatgtc aacataagct tgttcatcta
   113701 ttggcacaat aattgaaaat gctttttcaa tcattttgat taaaataagt gtattctttg
   113761 agatttcttc ttcagaatta ttactacgtg ataagaaatt gcttgtttca atcctttcta
   113821 tcgcaatagc aaggtggata gctaaagttt gaaattcata atctgtaaat ttcaattgtg
   113881 tcttattcat gtatcgatta agcaattcgg ctactttttt caatatgtcc ttatttaaga
   113941 aattattcgc ttcaccaatg aaattgatat tcaagtctaa gagatctgtt ttactgttag
   114001 atgctgtaaa gccaccccaa taatagttca caacttctga catcaacctt cttttacttt
   114061 tttcatcagc tttgatgcgc acgccatttc gatctgaaac taaggacatc ccatgcttgt
   114121 ttagtctttt tctaacatct ttcattgtgc tttctaccgt cgacctgctc acgtataatt
   114181 cgtcagcaag attttgaatc tttagagaat cattagtatt caataattta gcaaacacat
   114241 aagttagacg gtcctccgga gagtctgcga tattgatttt atgactggat aataaatttc
   114301 gaagtgtttc tttttttcca ataagcgaaa cgcctttttt aggttgaacc aacatttgta
   114361 catctggcat tttttggatt atttctttca aaattaaaat atctttgcta attgttttcg
   114421 tagatacata taattgttct gataattctt tgtaagttgt gtgctcattt tcaatcaaaa
   114481 agtatagtat tttcatttgc cgttcgctaa attcgatgcc cattatcttc acctcctgaa
   114541 tacagcttaa gtgtacaatt attatctcta ttttcataca gaagaaagtt cttgattaat
   114601 gtagaagttt ctaatattct tgattatttc aaatcaataa aaaagcctgc aatatttata
   114661 tcacaggctt ttttctctat taaatatata taagataata catttttcta ctagttctca
   114721 ctaatcttgt ataattaaac cctccgcaac ttgacggaga tggagaagat gcccccgtct
   114781 aatctagcgg tcatctctcc tcccattcct tccaccaatt tttttgacag gtaaagcccg
   114841 attccgctag attccgtatt tgtgcggctg gtattttcgg tataaaaacg ctggaagact
   114901 ttttcaacag aggtttgcgt tcctggtttg ataggattgg ccactgttaa tcgaatgaat
   114961 ggatcctctt ttgaaaatgt cacctttgct tgtccatctg cataacgcaa taaattctgt
   115021 atgatatttt gcagcactcg cagcaacatg agcggatctg ctaatacagt tgtatttatc
   115081 gagtgttcag cgaacgctac ctcgatattt ttctcagaaa attgttcata aaaagagaaa
   115141 aatacttctt ccacctcttt agaaaaagaa agcgtatgga gatccatttc tttttgcttc
   115201 gtctctattc gagcaagatc ataaaactga tccgtcatac tgagtaatct tgcaacagat
   115261 tgtttgatga tcgttaaata cttctcccgt ttctccgtat cctctacctg ttccagtaat
   115321 tgtacataac cgttaatagc agtcaaagga gttctgagat catgagaaag gccgacgatc
   115381 gatagtctga tgttttcttc catttcttga aatgcttgtc ctttttgttc attttcatcc
   115441 aaccatgtat tcagtgcatc tactaggtcc attagattct tttctcgaaa ttcgactgaa
   115501 agacgaccac catattcttg tcgttcagaa agagtggcga ttttcttagt taatctcttg
   115561 atttcccttt gcaggaagaa aataaaactt cccataaaga taacaacgag aagcaacagc
   115621 catttaatca aatctaaacc ccactcccca caccgtatga atatacacag catgtgcctt
   115681 tgctagcttc cctcgaagat tggaaatatg catattcact gttttctcac tatcaaaata
   115741 tggttcttgc caaactgttt cataaagatt tgctcgcgaa aatacttttt tcggatgttc
   115801 taaaaaaagc ttcagcagat cgaattctct tcctgtcaaa tggacagcca caccattcac
   115861 atttacatcc ctcgactctt tgtccagtaa gatttccttg taatagatgc gttgcgacag
   115921 atcttttact tggacagaag tctgatgacg aagttggatg ccgattcgta acaaaagttc
   115981 ttcgatatca aatggtttcg tcacatagtc atccgctcct gctgccaaca aggaaacttt
   116041 atctctttga tcgctttttg ctgaaagaac gatgatcgga acattcgatg tctgtcggat
   116101 ttctgctaac aatgcttcac ctgaaagccc tggaagcatg agatctagaa ggatcaaatc
   116161 gacaggatat gtgcttaaca ataattttcc ttccgtacct gaataagcat caagaagttt
   116221 gtatctctgt tcaagaacct cctccagtaa ggaatgaaca gcttcatcgt cttcgataat
   116281 caaaatagtt tccagcagga ccacctactt aatgtcagat ttttggaaaa taaacattcc
   116341 tagagctgat gataccacga ttgttactag actgaccaga atcattttcg gtgcttgcga
   116401 ataagttgct tgttgcgcaa agtccgtata catgagccac gtttccgtaa accactccgt
   116461 tagaaattcc aagcctttga tttttgcgaa aacaccggga atgaaggccg ttcccatgat
   116521 ataaagaaaa gaaagaagca aactgacact ggtacttcta gtgatgaatg tcaaagccac
   116581 tggaacagat aatgtcccta atgtcagcag aagcaataca ggaaatactt ttagaacata
   116641 atttccatag tttttgattc cctcaacttc accaaatccg aaagcaagtg tgtaagcaag
   116701 catggctagt cccgtgatca aaaccacgcc aagtgttgtg atcaaaagcg taacgagaag
   116761 tttcgacaca taataagtca ttcgattccg tcctaaagat aacgtattgc gaatcgtacc
   116821 gttttgaaat tcttccccaa tataaaagca cgcaaatgct gcgaaagcca gaagaatcca
   116881 tgcagccatt ttttctacca ttaaaatccc tgttgcaccg ttgatgactg tatccgttgc
   116941 ttggtttaat tcattgccgt attttgtatg catataccat tcgttccaag aataaaaaag
   117001 cggaagtacg accatcagtc ctagtgagac ccacatttta cggctcttcc atacttttat
   117061 tttttcagca gttaatagat taaacatgtg gattgcctcc agttaattgt aagaaataat
   117121 cttccagttt ttgcccaact aggtgaatac catccacagg aacttttgct tctaccaatg
   117181 cttgattgat ggctgctact tggtcaattc cttcaaaaag ctggataaca cggctagatt
   117241 gtacaaaata atccctataa ccaagagagt cgagaaccgt tactgcttgt tccgtcgccg
   117301 aagtgtcaat ttttataaat tgacgagatt cttgtgccaa ttcttctttc gataattctt
   117361 tgatcaagtg tccttcatgc aaaataccat agtgagtggc gatctgtgac aattcatcta
   117421 gcaagtggct agaaagcaag acggtgatgc cccgttcttt taccaaacgt tggatgattt
   117481 ctcgcatttc tgccatccct gctggatcca tcccattcgt cggttcatcc aaaatcaaaa
   117541 attctggatt cgtgatcagt gcatttgcaa tagctaaacg ctggcgcata cctaaagaga
   117601 aattctttgc tttctttttc cctgtatttt ccaatcgcat cattttcagc aggtcttcga
   117661 tttctctatc cgacacaccg ccgttcgctg cttggatacg taggttatct cttgcagtta
   117721 attctggata aagagcaggg gtttcaatcg attgacccat acgtcgtctt gctgcctgca
   117781 aatccgtcgt tccaaataat tcgatcgaac cttcatcaat cgagatcaaa cccataatag
   117841 ttctcataaa ggtagactta cccgctccat tttccccaat caatccatag atcattccac
   117901 gtttgatttc gattgatact ttatctaatg ctttggcagc accgtatttt ttggttatac
   117961 cagttgcttt caagaccgtt tcatttccaa aatccatact tatccttctt tcttattgat
   118021 gagtgaagta tagttgacgg gtataaagaa agcagccaga aatgtataaa gaaagtgtaa
   118081 attttccaat tgaatgtcaa aaaaaacaat cggacaatac gtgtctttcc tattatcagg
   118141 cagtttgtta tacgcttgta tcagtttcct gattctttct tttcgaccaa agtcgtttct
   118201 ctgtattcct cttcactgaa aatttttgct tctttcagat caagcttgag taattttacc
   118261 agaccggtta taaggataac tatagcaaga ctccctccca gaaaaattag actgtctcgc
   118321 agacgtggtt gcgttgtctt ccaatcaaag agcgcaccaa acagtgctaa tccaagtgga
   118381 ctggccacca tggtaatcgt tgttatcgtt gacataagtc gtccttgtat atgcgttgga
   118441 acttctcgct gaagccagac catataaaaa gcaaaagaaa acattaatcc ttaaaaacgg
   118501 acttatgaaa aataatacat gccgtttggg atttacaatt agctaccaaa taagaggtta
   118561 tgacaaaaga cttttcacaa tcccttcttc cgaataaacg gtgttctcct gccaactcct
   118621 cggtcacaag tcacaatatt tatcaaacat gagaagcaat ttttgtaaat tccttcttat
   118681 ttcttgaagc tgaccacttc tgtcacaacc tcagaagcgg ataaataata ttgtttgatg
   118741 atactttatc tttttcccgt ttgtttatag atcgaatgat attatagacc aagaatccta
   118801 cctattaaca tagctaaaaa cacaaaaaag gcactttcca aattgtggaa agtgccagaa
   118861 aagttaggat taaggtaact gcgctcagca ttgcttcgcc cagtacgatt ctcgtaactc
   118921 gtgaactcga acgataatcg caattaacgt tttgagaact gtgaagcttt acgggctttc
   118981 ttaagacctg gttttttctt cgtatcattg aataagtttg aaaaaccttg atttataaag
   119041 gttttcccgt aaatatattt tattatattt gattaaattt gaaatgtttg tgttctaaaa
   119101 tgtgttctaa tttaaaggca gtatatttcg tattttagat taaattttta ggctcattca
   119161 ttctcaaatc cattctattc agtcaataaa aattttaaaa agactttata aacaaagatg
   119221 ttcaagcgag catcttattt ttttgtgctt aatttgaaag gagaacattt catgtataaa
   119281 aaacaaaaaa agaaattatg tgtattaact attttgagtt tggctgttca agcaattgtt
   119341 ggagcaattg ctcctacgat tacttttgct gatgaaatta cccatccaca aacggtaacc
   119401 gtagaactag atttagcaca tcaatatgct gttgaaggaa cttttagtga tggtcgtcca
   119461 atgtcagaag tcactgttcc gcattatgca gtgtacaacg gctttaaaca agatattttc
   119521 tgtattgaac caggagtccc gatttacaat gagttcactc ctggctatga gaaaaacccg
   119581 ttaccagata tgtccgataa agccaaatta gtttccgttt tatggaaaaa agtaggtaca
   119641 gatgcagata ctcatattgt ggcacagaag atgatctggc aagaagttaa tgggtatacc
   119701 cttcactcaa taaaacgatc agatggtagt gccgtaaata tcgcagccat tgaggcaaaa
   119761 ataaatcaag ccattgacga ttatcagaag aaaccaacct tccataatag tacggctaaa
   119821 acagtattag ggcaatcgac tactgtgacg gatacgaata atctgaattt gtcagagttc
   119881 gatgaggttg tggaaaatgc cgcaaacatt gattatcgtg tgaatggtaa tcagttgata
   119941 atcaccccaa atgccaattc aaaagaaagt ggtgtgctga cgcttaagaa atctgctggt
   120001 accggaacac ctgtcgccta taaaaaggct ggccaacaga ctttaatggc cggggcgatt
   120061 gataaaccta atacctacac aatcaaaatt gatgtggaaa cggagggttc tttaaagatc
   120121 aaaaaagtcg ataaagaatc gggtgatgtt gtaccaggaa cggttttcca tttagacttt
   120181 ggaaaaactt tacctgcaaa agacgtgact actgacaaag aaggcattgc tacattggat
   120241 gagattcctc atggtacaaa agtaaccatt accgaaaaat cagtaccggc gccttatacg
   120301 attgatacca cccccatgac taccaccatt aaagcaggcg aaaccattta cgtgacttca
   120361 aaaaacgcac gggaaaaagg gcaaatcatt ctggataaaa gcggagttga aacagggagt
   120421 gatctttgga atgacaatta ttccttagct ggtaatacgt ttgccattcg caaagacagt
   120481 ccaaccggtg aaatcgttca agaaatgacc acggatgaaa acggtcatgc ggaaacacca
   120541 aaagagattg ctaatgcgtt ggaattggga acctattatg tgaccgaaac taaagctagt
   120601 catgggttcg tgaatacgtt caaacctgta aaagtcgaat tgaagtatgc caatcaaacc
   120661 gtagcccctg ttaccagtaa cgtaaaaggg caaaatcaag aagtcactgg cgaaaccact
   120721 ttgacgaaag aagacaaaga tactggggat aaagcacaag gtaaggcagt ctttgagggt
   120781 gctgaataca ccttgtttac tgctaaggat ggaaaagctg ttaaatggag tgaggctttt
   120841 aaaccagagt tagcgaaggg aacgaaaggt tctgatgaaa cggtcacttt gactttagac
   120901 gaaaagaacc aagttgccgt taaacattta gctatcaacg agtattattg ccaagaaaca
   120961 aaagcgcccg aaggatatag ccttgatgaa acaaagtatc ctgtatccat caaaaaggtg
   121021 gatgatagcg aaaaaaatgc cgtgattacc cgaaatgtta cggcaaaaga acaagtgatt
   121081 cgctttggct ttgatttctt taaatttgct ggatcagctg cgggcactac cgaaactggc
   121141 ttcaatgatc tgacctttaa agtgtcgcca ttggaaggga ccaatgaaat cacaggtgcc
   121201 gaagatgaag cgaccacagc ttataacgag caattagggt ttgatggtta tggcaagttt
   121261 gaaaatcttc cttatgggga ttatttactt gaagaagtag aagccccaga aggttttcaa
   121321 aagattacgc cattagaaat ccgttctact tttaaggaaa acaaagaaga ctttgtgaag
   121381 agtgagtatg tctttaccat taccgaacaa gaccaaaaac aaccaattaa aacggtgacc
   121441 gttccttacg agaagctgac gaacaaagca ttttctgtta gtttgaaccg tttaatgctc
   121501 tatgatttgc ctgaggaaga agatagttta acttctcttg cgacttggaa agacggaaac
   121561 aaagaattaa cttctctgga ttctaccgag ctagttgata aattgagtta caatctacat
   121621 gaaatcaaag aagactggta tgtggtagcg caagccattg atgtggatgc gacaaaagct
   121681 gcccaagaaa aagatgaaaa agccaaacca gtggtgattg cagaaacaag cgcaacgttg
   121741 gcgaacaaag agaaaacagg aacttggaaa attcagcata aattaaccgc cgaacaagtt
   121801 ttaaataaaa ctattgtctt attcaactat gtgtatgaaa ataaggaagc ttttgaagca
   121861 ggcgataagc cagtagcgaa ggatgttagc ttgaataacc aagcccaaac tgtcagttgt
   121921 acagtggaac accatgtttc tatccaaaca aaggcccacc tagaaaacgg ttctcagacc
   121981 tttactcatg gtgatgtggt ggatatgttt gatgatgtgt cgattactca tgatgtactg
   122041 gatggctcaa aagaagcttt cgaaacaatt ctgtatgctt tattaccgga tggtacaaac
   122101 aaagaaattt ggaaatctgg caagattgat tatgaagtaa atgataaaga attcaccaaa
   122161 actgtgcttg cgaaaaaagt agataccgga aaatatccag aaggaaccaa gtttactttt
   122221 gcggaaatca attacgataa agatgggaat atcaatggaa aacacaatga agatttgaaa
   122281 gaaaaatctc aaaccttaac accaaaagaa gttccaacca tactaagtac gccgaaacaa
   122341 ccggaaacac caactgttcc aagtggctct caagaatcta gtcccacagt gaagaccttc
   122401 cctcaaaccg gggagaaaaa ttccaatgtt ttactgttca ttggttttac tttgattttt
   122461 gcgacggcgg gctattattt ctggaatcgc cggaactaag gtgatgagat gatacaagta
   122521 aatcctaaga accaacgtgc gcgaccgcct cctaaaaaag tagtcgcgct atttttgtat
   122581 ccaaaactaa caatgaaaag aggaaaagaa gatggaattg aaatttgtcg tgccagatat
   122641 ggctgaaacc tttggaaagt taagttatgc cggtgaagga gaaattataa cagaaggata
   122701 tggacggaat actacggtga ttggtcgcag ttatcatttg tattccagta agcaacgggc
   122761 cgatgatatt gaggtggtag tagctgcgga agccggtgaa aaggattttg atcaagacca
   122821 accgctaaaa gccgtgaatc cccatttggt tgccaaaggc tatgagattg agaatcgtgg
   122881 gtttactgat tacgtgttgt atgttgatga tttagtgaaa gcataggagg aaaagaagat
   122941 gagattaaca gaaggtattg tcgtagattc aggtttaaca tttgggaagt tgcgtttttc
   123001 cgcattacgc cgagaagtac ggaagcaaaa tgaggatgga acaattggta atgaggtaaa
   123061 agaacgaacc tataatttaa aatcctctgc acaagggcga atgattcaag ttagtatccc
   123121 agctaatgta cccttacgcg agtttgctta tgatgcagag gtagagttgg tcaatccaat
   123181 cgtggatacc gttgccaatt atgtttttcg agaaggaact accgttaatt ggttcattaa
   123241 ggcggatgat ttagtcttga agcggcagcc gaatcaagga aatcctacga accaaaatga
   123301 aagaaagaaa taggtgaaga ttatggaaat taatgttgaa catattttag attgtctcga
   123361 tcaatatgga aaaggcgagc tgactgagga acaactcgtt aaagcattaa cctctgatga
   123421 aaaaatgttt ctgattatac atcaaggttt acttggagaa aatagcgaca gtgaagaaga
   123481 ctctgatgta ctagactggt taggagaaga agagtctttc tttatagttg tcgaagtaaa
   123541 tgaaaactta tgtcggcagg cagaatccat tttggaagaa attggtgtgg agatgccgga
   123601 tgctattgaa ggctttttaa atcaattggt tgaaacgaaa caactcccct cctcgtagca
   123661 gtaaatgact agcataactt tttgaaattg cctaatgaaa tcctattggg ctttttcgat
   123721 tggaggtgga aaccatcaaa atgtacaaag gacatcgcat acgcgcagga gatcagcact
   123781 tggtttatca ctttgttctt ggctggctac tcgctctgtt catcggttgg atgagcgtct
   123841 tttattttca agagtttaga caatttgata tttctaagct atcactttct actattgaaa
   123901 tcgtttggtc tataaaagat ttagtatgtc tgcttggaag tctcgctttt tcaggagcta
   123961 tgatattgct ttatattcac ttttttcttg atcattggcg aagcttgtgg catcgacaaa
   124021 agctagctcg gatgattcta gagaaccatt ggtatgaagt gaaacaaact caaagtgaag
   124081 gctttttcaa agatttgaat agtagccgaa ccagagagac tatcagttac ttccccaaaa
   124141 tctgttatcg aatgaaagat ggattactgt ctattcgcgt tcaaatttca cttgggaaat
   124201 accaagatca gcttttaaaa ttggaaaaga agttagaaag cggactgtat tgtgagttag
   124261 tagaaaagga actcaaagac tcctatgtgg agtatacttt actgtatgat atgatcgcca
   124321 atcgaattgg gatagacgaa gtagtggcag aaaatgggac tctgcgattg atgaaaaatc
   124381 aagtatgggc ttatgattct ttaccccata tgttaatcgc tggtggcacg ggtggaggga
   124441 agacctattt cctcctcacc attatcgaag cactattgaa gtcagatgca gaattgttta
   124501 tcctcgatcc caaaaatgca gatttagctg atttaggtac ggtgatgcct catgtttatt
   124561 cacaaaagga agaaatttct gcttgtgtgg aagatttcta tgaacgtatg atggctcgta
   124621 gcaaggcaat gaaagaaatg tctaactaca aaacaggaga gaattatgcc tatcttggac
   124681 ttccacccaa ctttttaatc tttgatgaat acgtggctta tatggagatg ttaacgacga
   124741 aagaaagtgc ggtgattttg aataagctca aacaaatcgt gatgttgggt cgtcaatctg
   124801 gtttctttct gattttggct tgccaaaggc cggatgcgaa atatttagga gacggaatcc
   124861 gcgatcaatt caactttcgc gtggctttgg gtcgtatgag tgaactcgga tattccatga
   124921 tgtttgggga ggtcgaaaaa aacttcttta tgaagcacat caaaggtcga ggttatgtgg
   124981 atacaggtgg cagtgtgatt agtgagtttt atacgccact tgtaccaaaa gggtatgatt
   125041 tcttagattc aattagtaaa ttagaaaaga tgaatgattg agtgatcttc aatactgact
   125101 ttatacttca agtaacgtat aatactttta tatagtagga agaaagggga taattaatat
   125161 ggaaagtaat gattcttatt tagagtatgc aaaagcaaat aaggataagt ttatttctta
   125221 tattatcaaa gggaaatccc ccgaagttgg acgagacgca gtttttatgg cagggagtcc
   125281 tggggctgga aaatcagagg ttgccattgg attagctgag aattatgata accatgtgat
   125341 tattgatgcg gattactttc gcacccagtt tcctgattat aatggaaaaa actctagtct
   125401 ctttcaaaaa gcatcttctt ggttggtaga gcaggcattt agatatgtct tagatcatgg
   125461 ctattctttt attctggatg caacttttgc aatattaagt gctgaaaaaa atatctcgcg
   125521 ggcgttgaaa aaacattttc gagtgacgat tttctatgtt tatcaagacc ctaaaatcgc
   125581 ttggaaattt acacaagaac gtgaaattgc agagggacgt catgtgccga aaaaggcatt
   125641 tattaacgct tttttcaaat caagagagaa cattgcaaaa gtaaagagta aacatccaga
   125701 tgtattgctt catatcataa taaaagatta tacgaataat atttccgaag ttcattatgc
   125761 tacggataat ctagaattat ttttaccact agggtatagt aggaaagatt tggaggttca
   125821 attacatgac tgagaaagaa caagtaacga aaattgtaaa gaaatacaat aagagcattg
   125881 cggatttatc ggaaaatgct actgcaaaag agttcaaaac ggtgattaaa tatgtagccg
   125941 atcaggccaa tgaaaaacaa cggaaattag ttggattaaa taaaaaatag taggacaaat
   126001 taataatgta tgagccaaga gcaaaatgtt cttggctttt ttctttgcaa tgaatgaggt
   126061 aatgtatgag atttttagat ttattcgccg gtattggtgg ctttcgttta ggtatggaac
   126121 aggcgagcca tcattgtatc ggtttttgtg aaattgataa atttgctaga cgtagttata
   126181 aagcaattca tgatacaagt aaggaggtgg aaatgcatga catcacaagt gtatcagatg
   126241 agtttattca atccctcgga ccagtggaca tcctttgcgg cggatttccg tgccaagctt
   126301 tttcaattgc gggaaagcgg caaagatttt ccgatactcg aggtacttta ttctttgaaa
   126361 tcgctcggtt caccactctt ctccgaccta agcttttatt ccttgagaac gtccgaggat
   126421 tgctcaatca cgaaggaggg gctacgttcg agacgatcct ccgaacgctg gatggattgg
   126481 ggtatgacgt ggagtggtag gtgcttaact caaaggccta cattccccaa agccgggagc
   126541 ggatattcct tatcggacat tctcgagacg catgtaccga acaagtattt cctatcattg
   126601 gaccgtcttc aacatctgat caaaacatca gaaatttggt aaatatcaat ccttccaatc
   126661 gaggaatggg tggacaagtc tatggttcag atggcgtagc gccaacctta acaggtgatg
   126721 aaggaatcaa aatcgcactg ccagcaaggg atggaatctc tgtagcagga ctattaccgg
   126781 gaaagtttga acaaggtaat cgagtttatg aagttactgg aaccgccccc accttgtcaa
   126841 cgaaacaagg tggtacaaaa atcatgattc gaaaaaatga aacagaatat caagaggtga
   126901 agccagaaga cagtgtgaat ctggcttttc ctaattccac aagtcgccga ggtcgtctgg
   126961 gaaaacagag tgttcatacc ttactaacag gagaccaaca agcgatcgtc acggatcagt
   127021 atcaaattcg gaagctaaca cctagagagt gttggcgact tcagggcttt cccgattggg
   127081 cttttgatcg agattctcaa gtcaattcag atagtcagtt gtataagcaa gccggaaact
   127141 ctgtaacagt tccggtcatt tttgatattg ccagaagatt aaaagagttg gatgtacatg
   127201 gtttatgatg agttgattgg agaaatttat tgggtgattg gaaagattca gtcagaccca
   127261 gaattagaag aacaattgcg acggttaaaa tttgatattc gcaagaatgg tgtcaaagtc
   127321 gctggcgatc catatttaat gaatgaggag acggatgctc gaattgaaat aaatcaagta
   127381 attgcagaat ttgagcggat tgcggaccaa gcaaaagaac cagatattcg tcaatacttg
   127441 ttagaaatga aagcagagtt ggaagtaaat ggtattacag atgagtaacc taaaccaaca
   127501 caactgactg ttaggcgctg accgcggagg attcgcgaag cagaaatcct ccgtggtgct
   127561 gtgcctgttc atggacggcg ttagccgacc atgatgtctc acccccgtat ctaacagggg
   127621 ggtacaaaaa cacaaaaaat aagtaagcaa ccattaagaa tgcttgttgt atcaaagata
   127681 gtaagtaatt tgtataggtg ttaactcatt tgaaaaagtt aacaccttga atttggaggt
   127741 gagaacttgg cacaacggaa tttagattat cggctattaa aagaccgacg caacgaatac
   127801 ggcgtttcac aaaataaatt ggctacggct tgtggactta gtcggccgta cttaaatcag
   127861 atagaaaatg gtggcgtaac cgcatctata aaaaccatga ggaaaatttt tgaccaactg
   127921 gaaagcttta atcccgattt gcctttgacg ttactgtttg actatgtaag gattcgcttt
   127981 cccacaacgg atgcacgaaa aattattcaa gaaattctcc atttgaaatt tgagtatatg
   128041 ctccatgaag attatgcctt ttactcctat caagaacagt atgtcatggg tgatattgtg
   128101 gtgatgttgt ctcatgaaga agataaaggt gtgcttttag aattaaaggg gcgaggttgc
   128161 cgacaatttg aaactttttt actcgctcaa aagcgtagct ggtacgactt tttcgaggat
   128221 tgtctaaagg ccggtggcgt gatgaaacgc ttggacttgg caatcaatga tcgagtgggg
   128281 ctattggata tacctgagct aacgaaaaaa tgtcagaagg aagaatgtat ctccttgttt
   128341 cgtaccttta aaagttatcg ttccggggaa cttttaaagg ctgatgaaaa ggacggcatg
   128401 ggcaatacct tatatatcgg cagtctcaag agtgaggttt atttctgttt gtatgaaaaa
   128461 gactatgaac aatatatcaa gttagggatt ccattagacc aaactgagac gaaaaatcgt
   128521 tttgagattc gactgaaaaa tgaccgtgct tttcatgcga ttcaagattt gttaaaaggt
   128581 cgtagcattg agagcaccac gttttccatt atcaatcgtt acttgcgatt tgcggataaa
   128641 gtagaaggta aaaggcgaac caactggccc ttgaatgaac aatgggggcg ttttattgga
   128701 cggaatcgga aagagattca attaacttcc gagccaaaac cgtataccat tgaacgaacc
   128761 ttgaattggc taggccgaca agtcgcccct acgtggaaaa tggctaagga gttggatcga
   128821 ttgaatcgga caacctatat ccaggatatg gtacagaatg cacgcttatc agaccgacat
   128881 aaaaagattt tggagcaaca aagtatggca attgaaaatt tgattatatg aaaagaggaa
   128941 tcgtcatggg aattgtaaaa gatatttttt tggtatttgg tggcagtatg cttggtgtta
   129001 ctgtgatgtg cttgatgaat gcaagtgcag cagcggatcg agcaatggaa aagaaaggaa
   129061 agtgacaaga tgaatttcgg acaaaattta tgtgcgactc gttccttagt gaaaagctaa
   129121 ggcactaata aaagaacgaa aaagtttggt tattaggaga actgataatc tgacaggtgg
   129181 aatgatgaag taacgctctg aaacgcctgc cctgagcctc cgacaagcat tgtatgagga
   129241 aactcagaat gtttgaagct cggtaaagac ggctgaaaga taccgtaata gttgatgaac
   129301 atatatcttc tatcgaaaac tatccagagg tgggtagcgt atccaacagg tcgggggtct
   129361 ataaaatatc tatggttaga atgttctata aggaactgac gaaacagcga atgtacgggt
   129421 ctaaatttga actttgtaga aatgcaaagg tacgagaaat cgtagctggt gtggcaaagt
   129481 aagaatatag gttatgaaat gccatataac gttacaggcg gtatcaagcc agcaggctta
   129541 tagctagtga cctaaggata tatatgtata gataagatta tcggaacgag gaaaggtatt
   129601 gggttctcat caagagaata aactgacgaa gaacaataag cagttgaact aatgctgaaa
   129661 agcagagggc gaacctaaga aattcttgta atgagaatgg aggaatgccc tcaagtcgtg
   129721 tatatattag aaaagtatta tgttgtttca ataaggatta cgagtaagat aaaaaagctc
   129781 actcaatttc aagtaaagga gtgaagcctt atgcctaaaa ataaaaatga aacattgtgt
   129841 gtagaagatt taagacacgc tgaatattac gaaatgcaaa acacctttga tgatttatat
   129901 gccaaaagta agaatggaga tattttcact catcttatgg atattatcct atcgagagaa
   129961 aatatattac tggcatatcg aaatatcaaa gcaaatgcag gcagtaaaac agcaggaaca
   130021 gacggtacaa taattaaaga tattggcaaa ttgccagcag aaacagttgt caaaaaagta
   130081 agatacattg ttgcaggcag tccacatggg tatcgaccta agccagtgag gcgaaaagaa
   130141 ataccaaaac caaatggtaa aaccagacct ctaggtattc cttgtatgtg ggacaggctt
   130201 atacaacaat gtataaaaca agtattagaa ccaatctgcg aagctaaatt tagtgaaaac
   130261 agctatggtt ttagacctaa taggtcagtt gaaaatgcaa taaaagcaac ctataaccgc
   130321 ctacaaatca gccagctaca ttatgtgatt gaatttgata ttaagggttt ctttgacaac
   130381 gtgaaccatt ccaagctgat aaaacagata tgggctatgg gaatacggga caagcacttg
   130441 atattcattt taaaaaggat attaaaagct ccaatcaaaa tgactaacgg tacaataaca
   130501 tatccagaga aaggaactcc gcaaggggga ataatatccc cactactagc aaacattgtt
   130561 cttaatgagt tagaccattg ggtagaaagc caatggcagg aaaatcctgt tacaaaaaac
   130621 tatgtggttc atatcaataa aagcggtagc ccatgtaaaa gcaacgctta caaagaaatg
   130681 aagaaaacaa agttaaagga aatgtatatg gttcgttatg cagatgattt tagagttttc
   130741 tgccgctaca aggaaagtgc tgaaaaagcc aaaatagcaa tcactcaatg gattgaacaa
   130801 cgattaaaat tggaagtatc acaagaaaaa acaagaattg taaatgttag aaaaagatac
   130861 tccgactttc ttggtttcaa gattaaaatg ataccgagaa gaaagaagtt agttgttaaa
   130921 tcacatataa gtgataaaca attcaaaaac caaaaagaca agctggtatc acaggcaaag
   130981 aaaattgctt ctccctcaaa agggaaaacg gaattagaag aaacaagact ttataattca
   131041 atggtattag gtatgcaaaa ttattatcag attgcaacga atgtaaatct ggattgtatg
   131101 aaactgaata gagctgtaat ggctatcttc actaacagat taggtacaaa caaaaggggc
   131161 agattgagaa aaacaggcag acaacttacg acaaaggagg caacaagata tggtaaatct
   131221 aaaatgcttc ggtatgttgc tggcgagggc gaacctattt tccctgttgg atatatccaa
   131281 cacagaaaac caatggcaaa ggtgtattta gcgaattgct acactctaga gggaagaaaa
   131341 tttatccaca ccaatctaag tgttgataaa ttactgatgt accagttaat gaaattatct
   131401 ttggaaaatc gcacaataga atacgcagac aatcgaattt cgctattttc tgctcaacat
   131461 ggaaaatgtg ctataactct ggaagaattt caacaagcta atgaaataca ttgtcatcat
   131521 attgtaccaa ctggagctgg tggaaatgac gattataaaa atcttatttt ggtaaaagag
   131581 gcggtacacc gtctaataca cgctaaaaca gaagaaacaa tacaaaaata tatagctcta
   131641 ttgaagctaa ataaagtcca gctcataaga ctaaataaat atagagtatt agctggcaat
   131701 caagaattaa acttgatata ggtctactac ataaatactt ttcaatataa acacgatgga
   131761 acgcggagtg cggtgaaagt cgcacgctcc gtgtgaatgg ggggaaaagt ttgagatatt
   131821 tataatatca ggaacttacc tatccatata tcaatggttt ttaaccaatg cccaatcctt
   131881 agtcttactg gcaattgtgg tcattggttt gtttttagga tttaagcggg agttttccaa
   131941 actgattggc tttttggtga ttgctttgat tgcggtcgga ttggtcttta atgcttctgg
   132001 ggtgaaggat gtcttactca gtttgtttaa ccgaattgtc ggtgcgtaag ggggaagcac
   132061 gatggaacag atgcgtgttt atattgcgaa cctcgggaaa tataacgaag gtgaattggt
   132121 gggggcgtgg tttaccccac ctgtcgattt tgatgaagtg aaagaacgaa ttgggttaaa
   132181 tgacgaatac gaggaatatg caattcatga ttatgaactt ccctttgaga ttgatgagta
   132241 tacgccaatt gaggaaatta atcggttgtg tggcttagcg gaggaacttg aaggaacgcc
   132301 agttggtgaa gttgcttctg agattcaaca tgctttcttc aattcttttg aggagatggt
   132361 agagcatgtg gatgatatta tctattatcc agattgcgat gatatgagtg atgtagcata
   132421 tttcttgatt gtagaagctg gtgattttgg agaagtacca gaacacttga agacgtatat
   132481 tgattttgat gcgtgtggta gagacttgga gattggaggc aattatttgg taacgagtcg
   132541 aggtgttttt gagtatccat attaacaaaa ttattgaagg gtagttgatt tctaaactat
   132601 ccttcttttt aaaggaatga tttgatgaag aaaataaaaa gctacaccag tatttgggca
   132661 gttgaaaagg tcatttatgc aattaatgac tttcaactgc cttttcctgt gacttttaac
   132721 cagatggctt ggtttgtttt atccttgctg tttgtcatcg tatttgccca tgtgcctcca
   132781 ctatctatga tagagggggc ctttttaaaa tacttaggta taccggtggc agttacttgg
   132841 ttcatgtcgc aaaaaacgtt tgacggtaag aaaccattgg gatttttacg atcttttatt
   132901 agctatcact tacgatttaa ggtcactttc gcaggaaaga aagtcaaaga acagaagaaa
   132961 cgatgggacg aacccattac tctggtaagg agtgtgaact atgtacccga ttaagtatat
   133021 tgaaaataat cttgtcttta atcaagaggg agaatgtttt gcctactatg agttaatacc
   133081 ttacaattac tcctttttgt cacctgaaca gaaatatcaa gtccacgata actttcgtca
   133141 attgattgcg caaaatcgtg aaggcaagat tcatgcctta caaattgcca cagaaagtag
   133201 tattcgtgcc acgcaagaac gatcaaaaaa ggaaattacc gggcgattaa cagaagtagc
   133261 gaaacaacga attgatttac agacagaggc attagtatcc atgattggcg atagtcagat
   133321 tgattatcgc ttttttattg gcttcaaact gattgcgaca gatgaagagg tcaatctaaa
   133381 gaatctcaag aaatctttct tctccggctt tcaagaattt gtctatggag tgaatcatca
   133441 tttgatgggc gattttgttt ccttatccaa tgaagaaatt cgccgatata ccaagcttga
   133501 aaaactaatg gaaagtaaat tggctcgaag atttaaagtc agacgagtca caccgagtga
   133561 tctgatgtat ttgattgaac atatctatgg cgaaaagggt acaccatttg aagaatatga
   133621 atttcagcta ccaaagaaaa agctgaagtc ggaaactttg gtgaaacgtt acgacttatt
   133681 acgtcccagt cgttgtttga ttgaagaaaa gccccggtac ttatgcatgg aacatgagaa
   133741 tcatgaatca tatgtagcgt acttaacaat taatacaatt gtgggggaaa tggagtttcc
   133801 ctcctcagaa cttttctatt accagcaaca acaatttaca ttcccaattg acactagtat
   133861 gaatgtggag attgtgacga acaaaaaggc acttgctacc gttcgcaata agaaaaagga
   133921 attaaaagac ttggacaacc atgcctatca atctgacaat gaaacaaatt ccaatgtctt
   133981 agatgcattg gattccgtag atgaattgga aactaccttg gatcagtcca aagaatccat
   134041 gtacaaactg agctatgtgg ttcgagtaag tgccgaatca gtagatgaac taaagcgccg
   134101 gtgtgatgaa gtgctagatt tttatgatga taccaatgta aaactagtcc ggccttttgg
   134161 cgatatgatg gggctacatg aagaattctt accttctagt aagcgataca tgaatgatta
   134221 tatccagtat gttacgtctg attttctcgc cggacttggt tttggcgcca ctcagatgtt
   134281 aggggagttg gaaggcattt actttggtta taacgtagat acggggcgca atgtttacct
   134341 gaaaccggca ttggcctcac aaggggtcaa ggattcagtt accaatgcgc tagcagcggc
   134401 attcctcggt tcactcggtg gcggaaagtc ctttagtaac aatctcttag tttattacgc
   134461 cgtccttttt ggtgg
//
LOCUS       DBBGRF010000002        93326 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000002 DBBGRF010000000
VERSION     DBBGRF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 93326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.002"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            83..970
                     /locus_tag="ACIZD4_000125"
     CDS             83..970
                     /locus_tag="ACIZD4_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC5989095.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="ACIZD4_000126"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="ACIZD4_000126"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGC5989096.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="ACIZD4_000127"
     CDS             2272..2718
                     /locus_tag="ACIZD4_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGC5989097.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="ACIZD4_000128"
     CDS             2991..4343
                     /locus_tag="ACIZD4_000128"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HGC5989098.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="ACIZD4_000129"
     CDS             4514..4801
                     /locus_tag="ACIZD4_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC5989099.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5027..5470
                     /locus_tag="ACIZD4_000130"
     CDS             5027..5470
                     /locus_tag="ACIZD4_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGC5989100.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5476..6660)
                     /locus_tag="ACIZD4_000131"
     CDS             complement(5476..6660)
                     /locus_tag="ACIZD4_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HGC5989101.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6928..7626
                     /locus_tag="ACIZD4_000132"
     CDS             6928..7626
                     /locus_tag="ACIZD4_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGC5989102.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7633..8310
                     /gene="nth"
                     /locus_tag="ACIZD4_000133"
     CDS             7633..8310
                     /gene="nth"
                     /locus_tag="ACIZD4_000133"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGC5989103.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8436..8969)
                     /locus_tag="ACIZD4_000134"
     CDS             complement(8436..8969)
                     /locus_tag="ACIZD4_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989104.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9266..11647)
                     /locus_tag="ACIZD4_000135"
     CDS             complement(9266..11647)
                     /locus_tag="ACIZD4_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HGC5989105.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11637..12284)
                     /gene="recU"
                     /locus_tag="ACIZD4_000136"
     CDS             complement(11637..12284)
                     /gene="recU"
                     /locus_tag="ACIZD4_000136"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGC5989106.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12348..12887
                     /locus_tag="ACIZD4_000137"
     CDS             12348..12887
                     /locus_tag="ACIZD4_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGC5989107.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12977..13396
                     /gene="gpsB"
                     /locus_tag="ACIZD4_000138"
     CDS             12977..13396
                     /gene="gpsB"
                     /locus_tag="ACIZD4_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGC5989108.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13418..13785
                     /gene="rnpB"
                     /locus_tag="ACIZD4_000139"
     ncRNA           13418..13785
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACIZD4_000139"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13994..15160
                     /locus_tag="ACIZD4_000140"
     CDS             13994..15160
                     /locus_tag="ACIZD4_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGC5989109.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15206..16702
                     /locus_tag="ACIZD4_000141"
     CDS             15206..16702
                     /locus_tag="ACIZD4_000141"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HGC5989110.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16783..17466
                     /locus_tag="ACIZD4_000142"
     CDS             16783..17466
                     /locus_tag="ACIZD4_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC5989111.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18111..19301
                     /locus_tag="ACIZD4_000143"
     CDS             18111..19301
                     /locus_tag="ACIZD4_000143"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HGC5989112.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19403..20356
                     /locus_tag="ACIZD4_000144"
     CDS             19403..20356
                     /locus_tag="ACIZD4_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HGC5989113.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSGNVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20425..21774
                     /locus_tag="ACIZD4_000145"
     CDS             20425..21774
                     /locus_tag="ACIZD4_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC5989114.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21957..22280)
                     /locus_tag="ACIZD4_000146"
     CDS             complement(21957..22280)
                     /locus_tag="ACIZD4_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989115.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22409..23572
                     /locus_tag="ACIZD4_000147"
     CDS             22409..23572
                     /locus_tag="ACIZD4_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC5989116.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23642..24991
                     /locus_tag="ACIZD4_000148"
     CDS             23642..24991
                     /locus_tag="ACIZD4_000148"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC5989117.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25036..25467)
                     /locus_tag="ACIZD4_000149"
     CDS             complement(25036..25467)
                     /locus_tag="ACIZD4_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5989118.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25855..28497
                     /gene="alaS"
                     /locus_tag="ACIZD4_000150"
     CDS             25855..28497
                     /gene="alaS"
                     /locus_tag="ACIZD4_000150"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGC5989119.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKEHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28697..29293
                     /locus_tag="ACIZD4_000151"
     CDS             28697..29293
                     /locus_tag="ACIZD4_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC5989120.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29415..30563
                     /locus_tag="ACIZD4_000152"
     CDS             29415..30563
                     /locus_tag="ACIZD4_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC5989121.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30601..31014)
                     /locus_tag="ACIZD4_000153"
     CDS             complement(30601..31014)
                     /locus_tag="ACIZD4_000153"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HGC5989122.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31093..31524
                     /locus_tag="ACIZD4_000154"
     CDS             31093..31524
                     /locus_tag="ACIZD4_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HGC5989123.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31623..31856)
                     /locus_tag="ACIZD4_000155"
     CDS             complement(31623..31856)
                     /locus_tag="ACIZD4_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC5989124.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32039..33709
                     /locus_tag="ACIZD4_000156"
     CDS             32039..33709
                     /locus_tag="ACIZD4_000156"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGC5989125.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33856..34242
                     /locus_tag="ACIZD4_000157"
     CDS             33856..34242
                     /locus_tag="ACIZD4_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989126.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34229..34927
                     /locus_tag="ACIZD4_000158"
     CDS             34229..34927
                     /locus_tag="ACIZD4_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGC5989127.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34932..35396
                     /gene="lspA"
                     /locus_tag="ACIZD4_000159"
     CDS             34932..35396
                     /gene="lspA"
                     /locus_tag="ACIZD4_000159"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGC5989128.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35393..36304
                     /locus_tag="ACIZD4_000160"
     CDS             35393..36304
                     /locus_tag="ACIZD4_000160"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGC5989129.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36539..37078
                     /gene="pyrR"
                     /locus_tag="ACIZD4_000161"
     CDS             36539..37078
                     /gene="pyrR"
                     /locus_tag="ACIZD4_000161"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGC5989130.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37092..38375
                     /locus_tag="ACIZD4_000162"
     CDS             37092..38375
                     /locus_tag="ACIZD4_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGC5989131.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38388..39314
                     /locus_tag="ACIZD4_000163"
     CDS             38388..39314
                     /locus_tag="ACIZD4_000163"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGC5989132.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39333..40613
                     /locus_tag="ACIZD4_000164"
     CDS             39333..40613
                     /locus_tag="ACIZD4_000164"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGC5989133.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40618..41694
                     /locus_tag="ACIZD4_000165"
     CDS             40618..41694
                     /locus_tag="ACIZD4_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGC5989134.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41699..44884
                     /gene="carB"
                     /locus_tag="ACIZD4_000166"
     CDS             41699..44884
                     /gene="carB"
                     /locus_tag="ACIZD4_000166"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGC5989135.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44938..45714
                     /locus_tag="ACIZD4_000167"
     CDS             44938..45714
                     /locus_tag="ACIZD4_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGC5989136.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45711..46643
                     /locus_tag="ACIZD4_000168"
     CDS             45711..46643
                     /locus_tag="ACIZD4_000168"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGC5989137.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46640..47356
                     /gene="pyrF"
                     /locus_tag="ACIZD4_000169"
     CDS             46640..47356
                     /gene="pyrF"
                     /locus_tag="ACIZD4_000169"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGC5989138.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47363..47992
                     /gene="pyrE"
                     /locus_tag="ACIZD4_000170"
     CDS             47363..47992
                     /gene="pyrE"
                     /locus_tag="ACIZD4_000170"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGC5989139.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47980..48294
                     /locus_tag="ACIZD4_000171"
     CDS             47980..48294
                     /locus_tag="ACIZD4_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989140.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48332..48973
                     /locus_tag="ACIZD4_000172"
     CDS             48332..48973
                     /locus_tag="ACIZD4_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HGC5989141.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49016..49708
                     /locus_tag="ACIZD4_000173"
     CDS             49016..49708
                     /locus_tag="ACIZD4_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HGC5989142.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49705..50607
                     /locus_tag="ACIZD4_000174"
     CDS             49705..50607
                     /locus_tag="ACIZD4_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC5989143.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="ACIZD4_000175"
     CDS             complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="ACIZD4_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HGC5989144.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            52661..53284
                     /locus_tag="ACIZD4_000176"
     CDS             52661..53284
                     /locus_tag="ACIZD4_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989145.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53734..54783
                     /gene="trpX"
                     /locus_tag="ACIZD4_000177"
     CDS             53734..54783
                     /gene="trpX"
                     /locus_tag="ACIZD4_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC5989146.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54780..55661
                     /locus_tag="ACIZD4_000178"
     CDS             54780..55661
                     /locus_tag="ACIZD4_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989147.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55664..56434
                     /locus_tag="ACIZD4_000179"
     CDS             55664..56434
                     /locus_tag="ACIZD4_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989148.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56713..57567
                     /gene="aroE"
                     /locus_tag="ACIZD4_000180"
     CDS             56713..57567
                     /gene="aroE"
                     /locus_tag="ACIZD4_000180"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGC5989149.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57745..58908
                     /locus_tag="ACIZD4_000181"
     CDS             57745..58908
                     /locus_tag="ACIZD4_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC5989150.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59025..59435
                     /locus_tag="ACIZD4_000182"
     CDS             59025..59435
                     /locus_tag="ACIZD4_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC5989151.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59609..61837
                     /gene="topB"
                     /locus_tag="ACIZD4_000183"
     CDS             59609..61837
                     /gene="topB"
                     /locus_tag="ACIZD4_000183"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGC5989152.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            61860..62165
                     /locus_tag="ACIZD4_000184"
     CDS             61860..62165
                     /locus_tag="ACIZD4_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989153.1"
                     /translation="MFIPKSENIAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTL
                     ILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            62325..62561
                     /locus_tag="ACIZD4_000185"
     CDS             62325..62561
                     /locus_tag="ACIZD4_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC5989154.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62558..62957
                     /locus_tag="ACIZD4_000186"
                     /pseudo
     CDS             62558..62957
                     /locus_tag="ACIZD4_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(63624..64568)
                     /locus_tag="ACIZD4_000187"
     CDS             complement(63624..64568)
                     /locus_tag="ACIZD4_000187"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGC5989155.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(64864..65808)
                     /locus_tag="ACIZD4_000188"
     CDS             complement(64864..65808)
                     /locus_tag="ACIZD4_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGC5989156.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66029..67243
                     /locus_tag="ACIZD4_000189"
     CDS             66029..67243
                     /locus_tag="ACIZD4_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5989157.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            67265..69280
                     /locus_tag="ACIZD4_000190"
     CDS             67265..69280
                     /locus_tag="ACIZD4_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HGC5989158.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(69363..70736)
                     /locus_tag="ACIZD4_000191"
     CDS             complement(69363..70736)
                     /locus_tag="ACIZD4_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGC5989159.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(70762..71046)
                     /locus_tag="ACIZD4_000192"
     CDS             complement(70762..71046)
                     /locus_tag="ACIZD4_000192"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC5989160.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(71048..73063)
                     /locus_tag="ACIZD4_000193"
     CDS             complement(71048..73063)
                     /locus_tag="ACIZD4_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC5989161.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(73242..73547)
                     /locus_tag="ACIZD4_000194"
     CDS             complement(73242..73547)
                     /locus_tag="ACIZD4_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HGC5989162.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(73636..74667)
                     /locus_tag="ACIZD4_000195"
     CDS             complement(73636..74667)
                     /locus_tag="ACIZD4_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC5989163.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            74874..75749
                     /locus_tag="ACIZD4_000196"
     CDS             74874..75749
                     /locus_tag="ACIZD4_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC5989164.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(75901..76743)
                     /locus_tag="ACIZD4_000197"
     CDS             complement(75901..76743)
                     /locus_tag="ACIZD4_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC5989165.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(76835..78712)
                     /locus_tag="ACIZD4_000198"
     CDS             complement(76835..78712)
                     /locus_tag="ACIZD4_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC5989166.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(78709..80130)
                     /locus_tag="ACIZD4_000199"
     CDS             complement(78709..80130)
                     /locus_tag="ACIZD4_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC5989167.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(80133..83522)
                     /locus_tag="ACIZD4_000200"
     CDS             complement(80133..83522)
                     /locus_tag="ACIZD4_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC5989168.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            83779..85170
                     /locus_tag="ACIZD4_000201"
     CDS             83779..85170
                     /locus_tag="ACIZD4_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989169.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(85243..85890)
                     /locus_tag="ACIZD4_000202"
     CDS             complement(85243..85890)
                     /locus_tag="ACIZD4_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5989170.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(85898..86584)
                     /locus_tag="ACIZD4_000203"
     CDS             complement(85898..86584)
                     /locus_tag="ACIZD4_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989171.1"
                     /translation="MKKILTMKKVTKTFGSGHTMVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(86590..87663)
                     /locus_tag="ACIZD4_000204"
     CDS             complement(86590..87663)
                     /locus_tag="ACIZD4_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989172.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            87885..88559
                     /locus_tag="ACIZD4_000205"
     CDS             87885..88559
                     /locus_tag="ACIZD4_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC5989173.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            88564..89904
                     /locus_tag="ACIZD4_000206"
     CDS             88564..89904
                     /locus_tag="ACIZD4_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGC5989174.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(90053..91039)
                     /locus_tag="ACIZD4_000207"
     CDS             complement(90053..91039)
                     /locus_tag="ACIZD4_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HGC5989175.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            91763..92794
                     /locus_tag="ACIZD4_000208"
     CDS             91763..92794
                     /locus_tag="ACIZD4_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5989176.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            92903..>93326
                     /locus_tag="ACIZD4_000209"
     CDS             92903..>93326
                     /locus_tag="ACIZD4_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HGC5989177.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT        29844 a        16563 c        18942 g        27977 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa
     4981 taggaaacaa aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca
     5041 actgctaata gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga
     5101 aatggaaaaa gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg
     5161 gaaaatccct gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc
     5221 catcagtaag ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga
     5281 agagaataaa aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag
     5341 acacgagcaa ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc
     5401 aaaagaagaa tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag
     5461 tagcaaatga agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa
     5521 tccgaatacc gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc
     5581 gatgacgcgc gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt
     5641 atctgagaca gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa
     5701 accataacag ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt
     5761 gatgaataga taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga
     5821 aaattttttg agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat
     5881 caaagagaag cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg
     5941 agaaaagata gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa
     6001 aggaataacg gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga
     6061 gaaacttaaa tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc
     6121 ataaacggca tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa
     6181 ctcagctaat agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc
     6241 catccatcca aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata
     6301 taaggtggag atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca
     6361 tatcgaattt cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat
     6421 aaggatcgga tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa
     6481 ggcagctaga gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga
     6541 gtgagaataa ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc
     6601 agtgaataag acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat
     6661 gtaaaaactc ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt
     6721 gtttccttgt caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag
     6781 tgaagatacg catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg
     6841 accgatcagt gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt
     6901 atactgtgat tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga
     6961 caaacagtca tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa
     7021 gaatttttat ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat
     7081 ttgcagatga ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat
     7141 cgtctcgtaa caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca
     7201 gatcgatata atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa
     7261 aaaaaatacg aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa
     7321 caagaatttg gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa
     7381 gaagaccatt atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag
     7441 gcttatagtt ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt
     7501 acaaaacaac aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa
     7561 gtagaacagt cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag
     7621 gagtagcgga atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga
     7681 atgtttcccg aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca
     7741 gtgatcttaa gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt
     7801 gcctcttttc cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa
     7861 ataaaaacga ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag
     7921 ctgattgaac gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct
     7981 ggtgtaggca gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc
     8041 gcagtagata cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct
     8101 acggtcatgg aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag
     8161 acacatcata cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc
     8221 gaggtatgtc ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa
     8281 aaggcgctaa aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta
     8341 tgaattatct tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt
     8401 aaatgtacat actcagtagc taggatggta acttattaca atttattgcg ataaaaataa
     8461 aagttgttat ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct
     8521 ataaaataag tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt
     8581 gtaataaaaa tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg
     8641 gatttgggcg gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa
     8701 aaagtgagaa tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt
     8761 aaaagtacag aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat
     8821 aataaacaaa atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa
     8881 aaaagatggt gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag
     8941 ccttctttca aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg
     9001 ggattattaa gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata
     9061 aacaagtaaa tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta
     9121 agctaaatgt tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac
     9181 agcttggtac atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac
     9241 gcttgtagac gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg
     9301 gtgtatggtc atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag
     9361 gagcagatga agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag
     9421 acgctggctc gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc
     9481 tttgactagt agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct
     9541 ggacatagct ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat
     9601 attgatcttt gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt
     9661 ctgtatttgt cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta
     9721 cgtgtgacga ttctgaagtg acaggtgtca tttttttatt gtaacctgtc cacacggaaa
     9781 tcgaataatt tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac
     9841 caagttttgc atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata
     9901 acccagcgat ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg
     9961 tgatcatata agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt
    10021 ctgttccgtc ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat
    10081 tggcgaaagc cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat
    10141 cttgttcttc cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc
    10201 caagattttt taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg
    10261 ctggaacatt acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat
    10321 tatcccagtt tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag
    10381 tttttccagt agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca
    10441 tcgtagaacc aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt
    10501 ctgcgatgtg acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg
    10561 tggaggcaac ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat
    10621 catatagttt cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt
    10681 agacattctt atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga
    10741 cgatcttagt attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat
    10801 taacagcttg atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa
    10861 cagtatctcg tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg
    10921 cttgaggcat cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac
    10981 caaagtacat ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat
    11041 ttacgtagta ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc
    11101 acgcttcttg ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa
    11161 gtttgatcaa ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag
    11221 agagggcaga accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat
    11281 cttctaccga cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt
    11341 cacgcttttc tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag
    11401 atacggtagc gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga
    11461 aaagtcctac acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct
    11521 tgataaataa tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct
    11581 tcttcacact ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat
    11641 ttgccattct tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc
    11701 aaataaggaa tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa
    11761 gataaaggta gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga
    11821 acactattca aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc
    11881 ccattttgtt cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag
    11941 ggaaaagatg ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag
    12001 acgccattat agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca
    12061 cttctcttag gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc
    12121 gccaacccgc gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc
    12181 ccccgattgc cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag
    12241 gcattcttat aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct
    12301 aggccacatt atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa
    12361 aagtaatcta tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc
    12421 ctaaaatcca agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag
    12481 ggctggaatg ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag
    12541 tagcggaatt gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg
    12601 attttggtaa taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag
    12661 cagattatgt cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc
    12721 acactcgttt tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc
    12781 ctggaaaaac gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg
    12841 aaattcggct gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt
    12901 tgatttatca acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa
    12961 aactagaggt gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga
    13021 attcaaaaca aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat
    13081 catcaaagat tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg
    13141 attgagtgca aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca
    13201 acaaacagag gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc
    13261 aaatcttgaa cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc
    13321 agcacaacct aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa
    13381 aacacgtcaa ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga
    13441 cttgatcagg ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc
    13501 ttagcgaaac cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct
    13561 tcggctatgc ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat
    13621 ccggtggaac gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt
    13681 gtctggaaga agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg
    13741 ttttttctcc ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag
    13801 ggaattaggt cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta
    13861 tttttcaata cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta
    13921 ttcggaattt gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat
    13981 aaggagattg tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg
    14041 gctagaagca ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa
    14101 cggacgtgca cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg
    14161 tacagcagat cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt
    14221 gtttgaaaac gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc
    14281 tgtagctgga aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac
    14341 aaaaaaagca atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact
    14401 gacggaaact ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt
    14461 aactctggat acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg
    14521 agcaccattg aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga
    14581 ccgtccattt tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat
    14641 aggccataat atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt
    14701 cagtcaagaa atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat
    14761 tgaattagat attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa
    14821 tgcagaagaa atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt
    14881 caaaacggat aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg
    14941 agaagaagaa actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa
    15001 aacatggagt aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa
    15061 agcaaccaaa aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg
    15121 gggaactcgt ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc
    15181 aattggatgt ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga
    15241 aatcaatctt ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc
    15301 tgaaaaagct agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc
    15361 aaaaaaaatc ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga
    15421 attgtcggaa gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca
    15481 tcgcgtaccg gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca
    15541 atggcaaaaa gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa
    15601 tattgaatta acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga
    15661 tgttttgctg aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga
    15721 tcagcttaaa gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc
    15781 tgaaacagac tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa
    15841 agtaatcgaa caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc
    15901 atttatgact ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga
    15961 tttcaaaatg gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga
    16021 catcgatgat aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga
    16081 atcacaatcg ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca
    16141 atatcctttc tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt
    16201 ttatcgttca ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac
    16261 ttaccctctc catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt
    16321 agatgttgct gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg
    16381 accaacaaat gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg
    16441 ttattttccc tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca
    16501 gcaagaaata gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg
    16561 gatgtcagag catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga
    16621 tgcaacacat gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt
    16681 taatgtatat caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct
    16741 atagatgttt tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg
    16801 atcgctgatt atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat
    16861 accaaaagag ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc
    16921 tttgtgacgc ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat
    16981 gagaacgagg caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa
    17041 cagatctcga tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa
    17101 gcggccgaac tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta
    17161 ggagcaatcg gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt
    17221 gatcctgaac tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca
    17281 gtgatcaatc atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac
    17341 ggatatgaag aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt
    17401 ctggaatggt ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa
    17461 aaatgatgga ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta
    17521 aaagttactt ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt
    17581 cacaaggaac aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt
    17641 cggaattggc aggagaacac cgtttattcg gaagaatagg actgtgacaa gacttttgtc
    17701 acagtccttt tttcgaattc aacaagtaaa acttttaaga aatattcaga gagtaaaatt
    17761 aaaaattgct gataaacgaa gatggaaatt ttatgtattt ttattggtct atgcaataaa
    17821 taaattaaat attcagaata caattgattt taacgaaagg gcttctatca atggttgtgt
    17881 tgtatttatc tgcccaggta gagtaaaata gatcattatc taaaaggtaa ttgttcatac
    17941 tatataagtc atttgaaagt aaaaagatac tgtaaataaa aaatgtggtt aaataattct
    18001 cataatcagt gtaagcgtta tcaaaaatat agcatacttg ctttgtagat gaatgacacg
    18061 atatatgttt ggtatgttct gcaagacaga tgaatatgga ggtggagaca atgtcttcca
    18121 aagaactaac aatgtattta gagaaagaat tggatcaact gaaagaaaag gggttataca
    18181 atacgatcga catactagaa agtgaaaatg gtgcttgtat catcgtagac ggaaaaaaga
    18241 tgatcaatct agcatccaac aattatcttg gatttgccaa tcgcgaagaa ttgaaaaaag
    18301 catgtattga agcaaccgaa acttatggtg taggagcagg agcagtccga acgatcaatg
    18361 gttcgctgaa aatccatcag caattagaag aaaaaatcgc agaattcaaa gggacagaag
    18421 cagcaatcgc ctttcaatct ggattcaact gcaatatggg cgctatctct gcagtaatga
    18481 caaaagaaga tgctatctta tcggatgaat taaaccatgc atctattatt gacggttgcc
    18541 gcttatccgg agcaaaaatc atccgaatta aacatcaaga tatgaaagac cttgagaaaa
    18601 aagcaaagga agcgatagaa agtaagaaat ataaaaaaat catgtatatc acagatggtg
    18661 ttttctccat ggatggagac attgcacgat tgccggaaat tattccgatt gttgaaaaat
    18721 atggactgat cacctacgtc gatgatgcgc acggctcagg cgtaactgga aaaggtgcag
    18781 gaaccgtcaa gcattttgga ttaagcgaca aaatcgatat gcaaatgggc acgttatcga
    18841 aagctatagg tgttgttggg ggttatgtag ctggatcgaa aacactaatc gactggttga
    18901 aagctagaag tcggccattc ctattttcta cttcgctaac tccaggtgca gctgcagctg
    18961 cattggcttc gattactttg atgcaagaac atccggaact tgtcgaaaaa gtttgggaaa
    19021 atgctaatta ttttaaagaa gaattgaaaa aagtaggcta taacatcggt atgtctgaaa
    19081 cacctattac tccagtcatt ttgggagacg aaaaagtgac tcagactttc tctaagaagc
    19141 tgatcgaaca tgggatttat gctaaaccaa tcgtttatcc aactgtgcct cttgggacag
    19201 gcaggatcag aaatatgccg actgcggaac atacgaggga aatgcttgat gaagcagtag
    19261 cagtttatca aaaaatagga aaagaaatgg aaattattta actaaattta gttttttcgt
    19321 ctatttaaaa ttagagaaca tgttcacgca tatattgtta atcatctgaa gatagtagta
    19381 aaaaagatca gggaggatca tcatgaaaaa agtattggtg acaggatgtt taggacaaat
    19441 tggttcagag ttgatcacac ggctacgtca agaactaggc agtggaaatg tcattgcgac
    19501 agatatacgc atgcctgaag tcattgagaa aaacgatatc tttgagatcc tagatgtaat
    19561 ggattacgaa aaaatgcgca gcatagcaga acaatatcaa gtggacacat tgattcattt
    19621 ggctgctctt ttgtcagctg ttgcagaagc aaaaccacaa ttagcctgga atttgaacgt
    19681 gactgggctg gtcaatgcat tggaagtcgc tagagaattc cagctgaaat tttttacgcc
    19741 aagttcaatc ggcgcgtttg gtccaaatac tccaaaagat cataccccac aagatactct
    19801 tcagcgtcct acaaccatgt atggggtaac gaaggtagct ggagaactac tatgtgatta
    19861 ttattatgtg aaatatggcg tagatactcg tggtgtccgt ttccctggat tgatttctta
    19921 tgcaaccttg ccaggaggcg gtacgacaga ctacgcagtc gatatttatt attcagcaat
    19981 caaagaagga aagtacacta gtttcattga tcaaggtaca tcaatggata tgatgtatat
    20041 gccagatgcg atcgatgcca ttataaaact catgaatgca gatcctgatc gattggttca
    20101 tcgaaatgcc ttcaatatat cggcgatgtc ttttgacccg gaagagatca aagcatctat
    20161 tcaaaaaatc ataccagatt ttgaaatgga ttatgatgtg gatcctgtac gtcagtcaat
    20221 agcagaatct tggccaaatt cactagatgt ttcttgtgcg caagaggaat ggggcttttc
    20281 gccgaaatac gacttagatg tgatgacaaa ggatatgttg gaaaaactga aagaaaaatt
    20341 ggtagagacg gtataaaaca agaaccacat ccaaaaagtt ttttatactt ttgggattgg
    20401 ctatggtatg aaaggggaca agggatggaa gaatatcaag ccacgccagt aaaagaagta
    20461 aaaatagaaa atgaattaaa acgtacgatg ggatttttta ctgctttatc gactgttatg
    20521 ggcacagtga tcggtgcagg ggtatttttt aaagccgcaa gcgtagcaga agttacagga
    20581 tccgccagtt tgcatatgtt ttcttggttt ctcggtggta tgatttctgt ctgtgcagga
    20641 ctaacaggag ctgaactggc agctgctatt ccagaaacag gagggatgat taaatatatc
    20701 gaacggattt acggaaatac agcagctttt ttattgggct gggcgcaagt cgtgatttat
    20761 tttccagcaa atgtagcagc cttgtcgatc attttcggta cacagttcgt caatctattt
    20821 ggtctttccc agtcaatgat tgttcccgta gctgttacag ctgctgtatc gatcctgttg
    20881 atcaattttt taggttctaa agctggaggg gcttttcagt cgattacgct tgtctgcaag
    20941 cttattcctt tgtttgtgat cgtcattttc ggtttgttcc gacaagaagg agtagacttc
    21001 caactgtttc cgatccaagc aggagaaaat ctttcatttt tctcagcctt gggagcgggc
    21061 ttgctagcaa cgatgttcgc atacgacggt tggatacacg taggaaatat ttcgggagaa
    21121 ttgaaaaagc cggcgaaaga tttgccaaaa gcaatttctt taggaatcat cggaatcatg
    21181 atcgtttatt tattagtaaa tgcggtgttc ttaagaaccg catctatcga cggagtcgca
    21241 ggaaacagca atgcggcaag tgacgttgca aaaatgattt ttggcggctt cggtggaaga
    21301 ctggtcacag ttggtatctt gatttctgtt tatggaacca tcaatggcta tacccttact
    21361 ggaatgcgtc tcccttatgt tatggcaaaa gaaaacaacc tgccttttag caagctcttt
    21421 gctaaacttc atgataaaac taaagttcct gtagccgcag gtatcttaga gctagtcatc
    21481 gctattggca tgatgatgat cggtggtttt gatacactaa cggatatgct gatctttgtc
    21541 atttggattt tttatacgat ggtctttgtt ggtgtcattc ttcttcgtaa aaaagaacct
    21601 gatttgtttc gaccatacaa agttccaatg tatccgttta ttccactagt agcaatcatt
    21661 ggagggactt ttatcgtatc aagcacgctt atcactcaga cctttttagc ttcgatgggg
    21721 atagtattga cacttgctgg tatcccgatt tatctctatt taaaacgtag atagctaaaa
    21781 cattcgaatt ttattagaac tgcacttctc tgccaaacaa aatattttat ttaaatgagg
    21841 agtacgtgga agaaatgtca aaagtactcg ttaattttga tcacgtaaat gtcgttttgt
    21901 ctacgatgaa atagcaaagt aaaagacaga aatcgggctc aaccgatttc tgtcttttac
    21961 tttgatttgc gtaactgaac tattcggcgt acgccgcgat aaatatttaa taaaaccaag
    22021 caaccagaaa tgaaaatggg aagccaaatc agatagacag ggtagccaag cactttagac
    22081 aaagcatgtg gagtcatttt atccatttca agaagtgctt gctgccaagt ctgaagattg
    22141 aagactagca tgaaacccga aataatcagg agaataaatc ctaaataatg aattgtagtt
    22201 ctttttctta cataagcgat cgtagcataa aggaacagta aaaaaatagg tacgccaaaa
    22261 acaaagtaca tattcagcat ctcgacaccc cctttgtgtt tatcttactt tactttgaaa
    22321 gaaatgagaa ataatagcct cgttacttgc ttgaaacagc aaaggactgc taagataaga
    22381 gagatacaaa gaatcaagga ggagtcatat ggcaagttat atcgaaccga ttcgttttgc
    22441 gctgattgtt tttccatttt tagccttagc gatctcatct gtttttttta tttatgaata
    22501 tcgaaagtat ggaacatttc tagtaacaag ggcagttatt ttgtattctt tcgtttttta
    22561 tttattgtgt gcgtattttt tggtgatctt accacttccg gcaaaggaga cggttgccca
    22621 aatgacaggg ccaaagatgg agctgcattt atttgcttca tggcaacatt tcagagacaa
    22681 cacggtattg gtcttgtctg aacctagtac ctacctgccg gcaatgaagc agagtgtatt
    22741 tttggaacca gcttttaatg ttttattact cataccattt ggcatttatt taagatatta
    22801 tttccggctt tcttttatga aaacgatgat tgctagtttc tgcctttctc tattttttga
    22861 attgacgcag ctaagtggac tttattttat ctacccaaga ccataccgct tatttgatgt
    22921 gaatgattta gtgacaaata cattgggtgg aatcattggt tttgtcgtta cgccgttatt
    22981 tacatttatg cttcctacaa gaagacgaat ggatgaactt tcttatgaaa aaggaaagac
    23041 tgtctcattg actcgacgct tggtcgctta tttgatcgac tggacatttt tatctcttat
    23101 taatttggta gcggcgattt tctttaaaat tgcgttcgat tcaggggcag ttacttctca
    23161 tatctggtgg cttttattag aagtaggggt atactttatg attgtaccgt ttataaccaa
    23221 tggatggaca cttggcaaaa aaattgtgcg tatccgtttg gtggaagaag accgcgaacg
    23281 aatttcttta aaagcattga tgatccgcta cgggtatctg tactttcttt tttatggttt
    23341 aagctggttg gggcagttgc ttcagcaaat catgaattcg acaacgaata cggtgttgca
    23401 gatgagtgca gtattcattt ctctcggtgt cttgttacta caaggtattt ttattttaaa
    23461 tatcttgcta tcatttttga gaaaaaaacg gattctgttt tatgaaaaag ctagtcacac
    23521 atatactgtt agcacgattg gccaaacaaa ggatgatgat tctcgaaatt agctgagcaa
    23581 aaacgctttg tctgtgttat aatgccaaag tcgtgataat ttaaagagaa gaggtgcacg
    23641 aatgaataat tttgatatat tccgcttcaa accgtttatc aatgaagcgt taaccgcaaa
    23701 gggcttcaaa cagcccacag aggtccagga acgtttgatt cctttaattg caaaaggaaa
    23761 aaatatcatt gggcaatctc aaactggtac aggaaaaaca catacgtttt tgttgccttt
    23821 gtttgaaaaa atcaatgcag aaaaagagga agtacaagtt gttattacag ctccaagtag
    23881 ggaactagct gcacagatct atgaagcagc tacacaaatc gctaaatttt ctacaccgga
    23941 gatccgtgtc tcgaattttg tcggcggtac agacaaacag cgtcaattaa atcgtctgca
    24001 tcaccaacag ccacaggttg tagtaggcac gcctggtaga atattagaca tgatgaatga
    24061 acaagcgctg aagattcaca ccgcatttgc atttgttgtc gatgaagcgg atatgacatt
    24121 ggatatgggt tttttaaatg aagtagacca aattgcaagt cgattaccag aaaagctgca
    24181 gtttttagtt ttttctgcca ctattccaga aaaacttcgt ccattcttac gaaaatacat
    24241 ggaaaatcca atcattgaag aaatcaaacc aaaagcagtt atttctgaag acattgaaaa
    24301 ttggctgatt tcaacaaaag gtaaagatga gaatcaaatg atttatcaac tgctgacaat
    24361 tggtcatcct tatttagcaa tcgtatttgc caatacaaaa cagcatgtgg atgaaattgc
    24421 cgattacttg aaaaaccaag gcttgaaagt agcaaagatt catggagaca tcaccccaag
    24481 agagagaaaa cgagtgatgc gacaagtaca gaatctggag tatcaatatg ttgtagcgac
    24541 tgatttagct gctagaggga tcgatatcga aggtgtctct catgttatta atgcagaaat
    24601 tccagaagat ctagacttct ttatccatcg tgtcggacgt actggacgta atggcttaaa
    24661 aggaacggcc attacgttat attcgccaaa tgatgagcaa gccattgatg cgatagaaaa
    24721 attgggcgtc tcatttgaac caaaagaaat caaaaacggg gaaatcgtca aaacatacga
    24781 tcgtaataga cgtgccaaac gagaaaaatc aaaagatgta ttagatccca cgctgattgg
    24841 tcttgtgaag aagaaaaaga aaaagatcaa gcctggttat aagaaaaaaa tcgattgggc
    24901 aattgcagaa aaaaataaaa aagaacgcaa aatcgaacgc agacagcaaa gccgtactgc
    24961 tcgtaaaaat aagaaaaatt cacataaata aaaaacaaga ggttgtgaca aaaggcgtgt
    25021 cacaatctct tgtttttaag ctagactttt tttcattccg atacaaagta cttcatcttc
    25081 aataaaaggt tctgtgcaag tatgataccc ttgtttttca taaaaatcta cagccgtcat
    25141 ttcagctact acataactag tctgacaacc ttctgaaacc gcccgttttt cagcagcttc
    25201 aagcaactga ccgcctaacc cttttcctcg gtattctttt gctacgcaaa atcgttccgg
    25261 cttgaagcaa gtaggtgttt tcttttcata acgcaaagta gctactggtc ttttttgatc
    25321 aagaaataga taataggttt gttgcgggat atcttttccg tcgaattcta gttctgcagg
    25381 aatcccttgt tctaatacaa aaacttgata tctcaaaaag cagctagctg cgcgtatcca
    25441 ttcatccgct ccaactattt ttttcatcat attcctcctt gtcatgaata gcagagatgt
    25501 attgattcct ttattcttat cgtaccaaaa atcgtggagt atgaccaaaa ggaaatgaaa
    25561 ataaaaattg agatattgac agtgatcaat agaatgcgta tactaaataa gtacgaaaag
    25621 gatatgattt gttttttaag actcacagaa aattctttct tggctgaaaa aagaatagtc
    25681 actaatcaaa ttgctccctt tttctatttt ggtagaaata ccgacgcagc tcagcgttat
    25741 cgagtttaag aggtaatgat tacacatcat tgcaatcaag gtggtaccgc gagttttcgt
    25801 ccttggctgt gatggtgttt ttttgtattt aatttataga aagcaggtaa tgacatgaaa
    25861 caattaagta gtgcacaagt tcgacaaatg tttcttgatt tcttccaatc taaagaacat
    25921 acgattgaac ctagtgcgtc tttgatcccc gtgaacgatc caaccttatt gtggatcaac
    25981 tctggtgttg caacattgaa aaaatatttt gatggttcag ttgtgccaga aaatccaaga
    26041 atcacaaatg cccaaaaatc tattcgaaca aatgatatcg aaaatgtcgg taaaacagca
    26101 cggcaccata cgatgtttga gatgctgggt aatttttcga ttggtgacta tttcaaaaat
    26161 gaagccatcc actgggcatg ggaatttttg actgatccaa aatggatggc attcgatcca
    26221 gaaaaacttt atgtaacagt ttatccaaaa gatacagaag caaaacgcat ctggcatgaa
    26281 gaagttggcc tgccactaga tcacattatt gatgtagaag acaacttctg ggatatcggt
    26341 gcaggcccat gtggtccgga tacggaaatt ttctatgacc gtggagaagc ttataacgat
    26401 ttagcagaag acgatcctga aaactatcca ggaggagaaa atgaacgtta tttagaaatc
    26461 tggaacttag tattttcaga attcaaccat aagcctgata acacatttga accacttcct
    26521 cataaaaaca ttgatacggg gatgggattg gaacgcatgg tctcaatcgt tcaagatgcg
    26581 tcaacgaact ttgagacaga cttgtttatg cctattatcc acgccgtaga aaagctaagc
    26641 aaacaagtaa aatatggtga aaacccagta acagatattt cttacaaagt aatcgcagat
    26701 catattcgcg ccctttcatt tgctattggc gacggtgcat tgccatcgaa tgaagggaga
    26761 gggtatgtct tacgccgttt gcttcgtcgt gctgtcatgc atgggaaaaa attaggtatt
    26821 gaacaagcat tcttatatcg tttagtccct gttgttgggg aaatcatggt aagttattat
    26881 cctgaagtac ttcaacaaaa agaatttatt gaaaaagtta tccgtacaga agaagaacgt
    26941 ttcaatgaaa caatcaatga aggtttggaa atcttaaatc aagtgatcca agaagtaaaa
    27001 aacgaaaacg ggacgactct agcaggaaaa gacatcttca aactatacga cacatatggc
    27061 ttcccggtag aattaacgga agaggtggca gaagatgaag gactgaaagt tgatcatgct
    27121 ggttttgaaa aagaaatgga tgcacaacgc gaacgtgctc gctctgcccg cagtactgaa
    27181 aaatcaatgg gggtacaatc tgctttattg acagatatca aagtagaaag taaattcatt
    27241 ggatacacag aacaagaatc agatagtcaa ttattggtca tcgttaaagg tgagtctctt
    27301 ttgaatgaag tcgcagaagg tgaagctcaa atgatctttg atcaaacacc tttctatgca
    27361 gaaatgggtg ggcaagtagc ggatcaagga tggatcatga atgaagtagg cgaaatcgta
    27421 gcagttgtta cagatgttca aaaagcgcct aatggtcaat ttatgcacac cgtagaagta
    27481 aaagcaccaa tgagtgaagg acaaacctat catctattga tcgatcaatc gatgcgcaat
    27541 cggatcatca aaaaccatac agcaacccat ctactgcaca aggcattgaa agaagtactt
    27601 ggcgagcatg caaatcaagc tggttcttta gtcgctcctg gacatttacg attcgacttt
    27661 acccactttg gtcaaatcac ttcagatgaa ttagctgaaa tggaaagaat cgtcaacgaa
    27721 aaaatctggg aagctatccc agttgaaaca attgaaacag atatcgatac agccaaaaac
    27781 atgggtgcaa tggctttgtt tggtgaaaaa tacggacatg acgttcgagt agtaaatatt
    27841 ggcggctggt caatcgaact gtgcggaggc acacatgtag caaatacaga aaacatcgga
    27901 atcttcaaaa tcgtttctga atcaggaatt ggtgcaggcg tgcgacgaat cgaggctgta
    27961 acaagtaaag aagcgtacga actacttgaa gaagaagaaa aacaactaaa acaagtagca
    28021 acaattgtta aatcacctca attgaaagaa gttgtttcaa aagcggaaca attgcaacag
    28081 caagtaagag agctacaaaa ggaaaatgaa caattagcta gcaagttagc gaatcaacaa
    28141 gctggtgatg tattcaaaga tccagaaacg atcaatggaa aaacaatcat tgcagcacaa
    28201 gtaaaagtga aagatatgaa tcagctgcgt caattagctg accaatggaa acaaaaaaat
    28261 atttcagata ttcttgtttt agcaaacgaa caagaaggaa aagtcagtct gctagcggca
    28321 atgacgaaag aatcaaatga agctggacta aaagctggcg acttgattaa agcaatcgca
    28381 ccgaaagtag gcggtggcgg tggtggacgt ccagacatgg cacaagctgg cgggaaaaat
    28441 cctgctggta ttccagatgc acttaaagct gcgaaagaat gggttgcgca acaatagggc
    28501 gtttacgttt gacagaaaaa caaaagttca aacattgaac gaaacatgat tatgggggcg
    28561 aagacaaaca agtcttgccc tcatactttt ttcaattgga tggcgcatct aatcaaatgg
    28621 tcggattcgg atggtcttta gttgacgaaa gtgacagaaa tttttacgat tagtataaat
    28681 aaaaaggggt gaaaaaatga atagtagaaa taagaccttt cgactagtct tacgtgcgat
    28741 cttgttagca atcatcatcg tacaagcgat ggttccttgg ctggggttta ttccattagg
    28801 attcattagt ttaacaatta tccatatcac agtaattatt gctgcagtag tattaggccc
    28861 aaaagatggc atggtgattg gcttgttttg gggaatcgct acaattgttc gtgcctatgc
    28921 catgccaaca acgccatttg atacattagt gttcacgaat ccgattatct cggtagttcc
    28981 cagagtactt gttggcttag tagcaggctt ggttttccac tggatttatc aaaaaaataa
    29041 atcaataacg atcagctcag cctttgcagg ggtactgggt tcattggtca atacagtctt
    29101 agtgttagga ttcatgggat tattttatac aggtgcaacg gcagatgcct atggtgtaga
    29161 ctctgctctt ttatttaaaa ccttagcagg ggttgcagca atcaatggga taccagaagc
    29221 aataggtgcg ggaatcataa caccattact agcaaaagcg ttatttgcag caacaccgtt
    29281 gaaaccagaa taatgaccat cttttaatag taataggacg cacgatagat agaaaaagga
    29341 agagaggaga ggaaaacaat cgtcctctcc atctttttac ctgagcaaca agcaaactag
    29401 aaggggtaaa aaacttggct aagaaacaag aagaaaaaaa gaaacaaata ccgcaacagc
    29461 ggacaaaaaa aggagtacta gcgggtatct taggattggt tacgaatctg atcttgtttg
    29521 tctctaagct aatgatcggg cttttttcag gaagtgtctc cattatggct gatgcagtga
    29581 acagtctatc agatactgct tcatccatat tgactttgat cggatttaaa attgctgcaa
    29641 agccagcaga tcaggaacat ccttatggac acgaacgctt cgaatatatc agtgggttat
    29701 ttgtttcgat catcattact tatgtaggat ttcaattttt agagtcttct gctgaaaaaa
    29761 tcatccatcc agaaaatgtc tctttaacac ccatcgtctt ttttgtccta atcatttcca
    29821 tctttttgaa atttgcacaa ggcaaaatgt atcaggttat tgcgcaatcc attgattctg
    29881 aaacattgag agctacagca acagatagtt ataatgatgt ctttactaca ctggctgtat
    29941 tgctttcagc agcaatcgaa tgggtaactg gatggcgtat tgatggatat ataggttttg
    30001 ctttagcatt atatatcctt tatagtggat tgacgatgct tcgaaatttt gtatacgaac
    30061 tattaggaag tcgcccaacg ccagcagaga ttgaagaaat ggaagagcat ttaaatgctt
    30121 gcgatgatat acttggctat catgatttat tggtgcataa ctatggaccc aataaacgct
    30181 ttgcatcagt ccacatcgaa gtagatgaat caatgaattt gaatgtggct cataagatta
    30241 ttgatctgat agaaaaagac tttaaaaagt ctttggatgt ggaacttgtc tgtcacttgg
    30301 atccaatgcc tgttgataac gaaaaatact ataatatctt gcggcagtta aagcaaattc
    30361 ttcttgaaac aggtacaggg cttaatattc atgattttag agtaattcat caaggaaaaa
    30421 cgctgcaatt tgatgtagtg gtccctgaga aattccagtt tgttgataca gaactagaaa
    30481 gaatcttacg tagtcaaata gaagaaaaaa tcggagatta ccaattggaa attacgtttg
    30541 atcacaatta tcttttatat taaatgagaa actataaaaa gactccttaa agtttttaat
    30601 ttaaagagtc tttttttctt ttaattgttt atggagagcc tgacgtgcaa gattatctgc
    30661 tcctttattt ttgttttcgg gcaaccattg caggatcaat aaagaaaatt cggatagaag
    30721 ttcttggatt ctttgaaggt agggaaggaa gagctcgttc ttcgttgcgt ttttgtcgac
    30781 cgtagaaact agtgttttgc tgtctgaaaa acagaaaatc gtttcattct gtaagtcgtt
    30841 tttctttaga aattctaaag tttttaaaaa gacttcgaac tctgcttgat ggtttgtccc
    30901 tatagaaagc gggatagata gctgttcttg tttaccttga tagacaatca agattccacc
    30961 tccactagga ccagggttgc cttttgtaga ggcatcaatg tatactttta acataaaaag
    31021 agattctcct ttttgttcaa actaatgtta tggtaagatt atatcattac tgaatcggtg
    31081 agaggttaga gaatgaaaaa aaatattcga tggcagcctg aactggcaca tacgatcatc
    31141 tattggtcat tgaccttgat cattctgttt tttagtctga ttctttcttt agaaaacaca
    31201 ggtccttatt ggaaaagcaa ttttgtttta ggtatttttc ttgtttttct atttctaggt
    31261 ttgcggcgtt cttttatttt aaaatcaaac tctgtgatta tacgttatgc tgctttttgg
    31321 aaagaccgag aaatatctgt cggacagatt cgatctttga cgccaactaa tactggggtg
    31381 caaatgatgt tgcaagatga gaaagcccca tctgttttca tgatgcgaaa aaaagatcaa
    31441 gtagtccttt ttgatcattt tgaaaaaaac ggacccaaat cagaatcaat tccttatcct
    31501 tatacgaaaa aaagaaaaag ctaattttaa aaatcagaac ctaaaaaaac gaatttttac
    31561 aggaaaagaa aagagtgaga cgtacggttc atcccgttta gcgtctcact ctatttgttt
    31621 atctattcat gcatactagt atcggtagtc tgaacgttgc ctttcttgac atgggcagct
    31681 tgtgttcctc gattcccttc gatgatctca aattcgacca cttgattttc ttccaaagtt
    31741 ttgaatccct cttcttcaat cgcagtaaaa tgtacaaaaa tttcttctgt gtcatcataa
    31801 ctgataaagc cgtatccttt tttgttgtca aaccatttta caattcctgt ggtcaaagca
    31861 ctcacgacct ttctaaagtc tgatcatagc cttcattata aagagtattt ataagtacgt
    31921 caaataaatt aaaaacctgt aattttatgt tttttttctg aataaaaaaa ggtataattg
    31981 gcatatctta acaaagaaga tattttgttg aataaagttc gtgaaaaggg gtaatcaaat
    32041 gaagaatgat ctgcaaattt cacaagaaac agagctagaa ccgattgttg aagtggctag
    32101 taaattagat cttaaggaag acgatttgga actgtatggg aaatataagg cgaaaatcaa
    32161 tttttctgga atcaatcgat caaaggataa cgctgagggg catttgatct tagttacttc
    32221 catcaatcca acaccagctg gcgaaggaaa gtcaacgatc actgtagggt taggagacgc
    32281 gctcaataaa atcaataaaa aatctgttat tgcattgcga gaaccctcac ttggtcctgt
    32341 gatgggaatc aaaggtggtg ctgcaggcgg aggatatgca caggtattgc ctatggaaga
    32401 tatcaacttg cattttactg gtgacatgca tgctatcaca acagctaata atgcattatc
    32461 tgctctttta gataatcata ttcatcaagg aaatgaattg aacatcgatg cccgccgagt
    32521 gatttggaaa cgggtagtcg atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt
    32581 gggtgggcca atccaaggtg ttccaagaga agatgggttt gatatcacag ttgccagcga
    32641 aatcatggct atcttgtgtc ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag
    32701 gatcgttgtc ggctatacat ttgaccgtca gcctgtgact gctggagact tgaaagcaga
    32761 aggcgctctg gcattactgc tgaaagatgc aatcaagccg aatcttgtac aaacaattta
    32821 cggaacacca gcttttgtcc acgggggacc gtttgccaat atcgctcatg gctgcaatag
    32881 tattttagct accaagacag cattgagatt agcagattac gttgtcacag aggcaggatt
    32941 tggtgcagat cttggcggag agaaattttt agatatcaaa gtacctaact tgaaaaaagc
    33001 gccggatgct gtggtgattg tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa
    33061 aaaagatgaa cttaaaaatg agaatcttga tgctttgaaa gtaggttttg caaatttaaa
    33121 gcgccatata cgtaatatgg aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt
    33181 cgtaacagat acagacaatg aactcacact gttggagcac ttgtgtgaaa atcaggggat
    33241 tcttgccaag agagcgagtg tatgggcaga tggagcagaa ggcggcgttg atttagcaaa
    33301 agctgtagta cgattgattg atagaaaaga agctaattac aagccattat accgcctaga
    33361 agaaacgata caagaaaaga cagaaacaat cgtcaagaaa atttacggag gaaatggtgt
    33421 tgttttcagc aaaaaagcgc aaaaacaaat agaagagttt acgaagaatg gatgggacaa
    33481 actgccgatt tgtatggcaa aaacacagta ttcattttct gatgatcctt cactgctagg
    33541 tgcaccggaa gatttcacca tcacgatccg cgaaatcatc ccaaaattag gggcaggatt
    33601 tttagtagcc ttgactggag atgttatgac gatgcctggt ttgcctaaaa aacctgctgc
    33661 attgaatatg gacgtgacaa atgacggaga agtgttggga ttgttttaag cttgattata
    33721 atctaccatc gaaggagctg tattttgact acagcttctt tttttagacg atagggaatt
    33781 aattttgttt acactaggat cattcttttt ctttattgta ttttgagcta tactaaagca
    33841 taataggagg gtatgatgaa aacgacattt ataagaaaaa ccggttttta cggtatgggt
    33901 agctcgattc agctaagaat caacaatgaa aaacgcagtg ttctcagtca tgaacaaaag
    33961 ataacgcttg atctggaagt gccctttacg atgcaggtca ccttttattg gctaaaaagc
    34021 cccgtttata cagtgaaaga agcaaagcct gcttatgtga tcacaatgaa ttacttgatt
    34081 cttcaaatct atccgttttt atttctagca actgggttgg gggccgtttt cctacaaaat
    34141 ttatttttca gtttttttgc agttattgtg ttgattgcgt tctttttcta tataaaaaac
    34201 cgggcatatt tgatcaagga ggaaaattat ggcaaactct gatctttttt taatcagttt
    34261 caatcgaatc gaaaaatgga tgagagacga gatgggaaat gcacgaaata tgggatttac
    34321 cgaacttgtc agacgcctag ctcaaagaaa acaattaatg atcagaaaat acgaagatga
    34381 tcttttacag cttgctcagt taaggaatgc gatcgtccat gatcggatcg cagtcgattt
    34441 tgtcattgca gagccaaatg attggacagt caagcgaatc cagctgatcg aacaagaact
    34501 gattcagcct gaaaccgtgc tgcctcgatt tgcaaaacgt gtaacaggtt ttgaacaaga
    34561 tcttccgtta cttgaactgt taaagatagt agcagaaaaa aggtattcac aatttccgtt
    34621 atacaataaa ggaaaatttg tagcattgat tactttacgt aatatcgggt tttggctagc
    34681 aaaagaaagc caaaaaggtc cggttgattt aacaaataaa cgagcgttgg atttgatcat
    34741 ccaaaacgga aagtacacaa attatcattt tgttccagct aaaacacata tttacgaggt
    34801 tgaagcgatg tttcgtgagc aagggacttt ggaagccgta cttatcacta aagatgggaa
    34861 tcccgatggt aatctgctcg ggatcgtacg acctcgtgat atttataaac aaatagaaaa
    34921 ggattgattt tttgttaatt atttattgga tattcagcgc tttgctagta ggagtggatc
    34981 agttggtcaa atggtggatc actgataatc tagcgcttgg agagacgaaa aatcttatac
    35041 caggtatttt gtcactgaat catattcgaa acactggagc cgcatggagt atgctagaag
    35101 ggaagatgtg gttctttact atagtgacac tcattgcagt cgttgtgatt ctcacattga
    35161 tgattaaaaa tcgtgaaaaa ggtaatcgct ggttcatgat tggattgagt ttgattctag
    35221 ctggtgcgat tggcaatttt atcgaccgta ttcgtcttgg ctatgtagta gatatgttcc
    35281 agacagattt tatgagcttt ccgattttta acgtagcaga tgtgacactt gtatgtggag
    35341 tgatttgtat gttaatttat attattttag atgaaaagga tcaaagaaaa aaatgacaga
    35401 acttaaaacg acgattcacc atgaatctgg taggatcgat aaagtattga ctaatttatt
    35461 caccgattac agtcgttcgc aaattcagct gtggctgaaa aatggagcgg tttctgtcaa
    35521 tggacagcca gtcaaagcaa attacaaagt aaaacaagga gacgagatta ctgtcttgat
    35581 ccccgaacca gaaacattag atgtggtccc agaaaatatc ccgttgacga tcgtttacga
    35641 agatgaagat gtagcggtga taaacaaacc tcaaggaatg gtcgttcatc cttcagcagg
    35701 tcatacgcat ggcacaatgg tcaatgcgct gatgtaccat atcaaggatc tttctacgat
    35761 caacggcgtt attcgtccag gtattgttca ccgaatcgac aaagatactt ccggactgct
    35821 aatggttgcc aaaaatgacc aggcacacga atcattagct cagcaattaa aagataagac
    35881 ctctttgcgc aaatatgttg ctttagtcca tggagagatt cctcacgaaa aaggaaccat
    35941 caatgcgcca atcggccgtt cgaaggaaaa ccggaaaatg caggcgataa gagaagatgg
    36001 gaagtcggct gtcacacatt ttactgtatt ggaacgtttc gaaggattta ctctggttga
    36061 attaaaacta gaaaccggaa gaacacacca gatccgtgtg catatgaagt atatcggtta
    36121 tccgttagct ggagatccag tatacggacc gaagaaaact ttgaaaggca atggtcagtt
    36181 tctccatgcg caaatgttag gttttacgca cccgactaca aacgaaaaga tgatctttga
    36241 agcacctctt ccagaagttt ttgaaaaaac tttagaaaaa ttaagaaaaa acattgcatt
    36301 ttaatttaga taacggtata gtaattaaca acgaaagcat aaaacttaat agaattcctt
    36361 taagtttagt cccgtgaggc taagaagggt gggagcaagg atacgtatgg tgcgccataa
    36421 gtagattgct cattgacata gtatagctat cagtgtatca gtatacgctc agtctaaaca
    36481 ttcctcctgt cctcttaggg caggagtttt tttatgcaaa aaagtagggg gaatgaaaat
    36541 gcaagcaaaa gaagtagtag atcaggtaac catgaagcga gcattgactc gaattactta
    36601 tgagattatc gagagaaacc atagtatcca agatatcgta ttggtaggta tcaaaacacg
    36661 aggaatctac attgcatcaa gaattgccga acgcctgaag cagctagaag atatcgatat
    36721 tcctgtagga gaactggata tcactttata ccgagatgac aaaaaagaaa atccagaaga
    36781 accggaactt cattcttctg acatcccagt ttccttagaa ggaaaagaag ttattttgat
    36841 tgatgatgtt ttgtatacag gacgaacgat tcgagcagca atggacgcag taatggattt
    36901 tggcagacca agaaaaattt cattagcagt cctggtcgat cgtgggcatc gagaattgcc
    36961 aatccgtgca gattatgttg ggaagaacat tccaacatct cgggcggaag agattttagt
    37021 agagatgcaa gagcttgatg gacaagatcg catcatgatt ttgaaagagg aagattagag
    37081 gagagagaaa catgtcggag aaaaaaggat ttcataatga tgacgtggtg ttagatatcc
    37141 acgatcgccc aaccccagga cattgggtag gattaagttt acaacacttg ttcacgatgt
    37201 tcggagcaac cgtgttagtc cccatcttag taggtatcga tccaggtatt gcgctagtca
    37261 gttcaggact aggtacattg gtgtacttat ttactactaa aggaaagata cctgcgtact
    37321 taggaagcag cttcgctttc attgcagcga tgcagctttt gatgaaaaca gatggttatc
    37381 cagcgattgc acaaggagca gtcacaactg gattagtcta tttgattgtt gcgctgatca
    37441 tcaaaaagat cggttcagca tggctggata aaatcttgcc tccaatcgtc gtcggtccag
    37501 tcatcatggt tatcgggttg ggacttgcgg caaatgcagc aacaaatgct atgtataatc
    37561 agggcacgta tgatttcaag tatattgctg tagcgctgat cacattagga ttaacaattt
    37621 tcttcaacat gtggctaaga ggttttctcg gattgattcc gattttacta ggtattatta
    37681 gcggatacat cgtagccttg ctgtttggaa tcgtggatac taagccaatc gtagacgctg
    37741 cctggtttgc tgttcctaac tttgagattc cctttgtaca atatgaacca aagctatatc
    37801 ttggagcaat cacaacaatg gcacccatcg cttttgtgac gatgacagag catatcggcc
    37861 atcttatggt attgaataaa ctaactaaac gtaatttctt tgaagaaccg ggtcttcata
    37921 agacgttgac aggtgatgga ttagcacaaa tcgtggcagc ctttgtcgga ggtcctcctg
    37981 taacaagtta cggtgaaaac attggtgttc tggctatcac acgtgtccat agcgtgtttg
    38041 tgatcggtgg agctgcagta tttgcagtca ttttaggatt cgtaggaaaa ttaagcgctt
    38101 tgattttaag tatccctgga ccagtcatct caggaatcag ttttatctta tttggagtaa
    38161 ttgccgcaag tggaatgaag attttaatcg agaacaaaat cgattttgat aaaaagaaaa
    38221 atctgttgat tgcttcagtt atcttagtag taggaattgg cggactcgtc tttgaagtag
    38281 gcacatttac attgtcggca atggcattag caactgtact tggcatcatt ttaaatctta
    38341 tcttaccaga aacttcacga agcgaagaaa actaaggagg aaacattatg atcatcaaat
    38401 cagaacgtat cagcttaaag catttattga ccgttgaggc acttactgat caagaagtta
    38461 tgggcttgat ccgcagaggg caggaattca agcaaggtgc taattggact ccgcaaaagc
    38521 gccagtactt tgctacaaac ctctttttcg aaaatagtac tcgcacacat aaaagcttcg
    38581 atgtagcgga gaaaaaacta gggctagaag tgattgaatt tgaagcaagc acaagctctg
    38641 tccaaaaagg ggaaacacta tacgatacag tactgacgat gtcagcatta ggcgtagacg
    38701 tagcggttat ccgtcatggt gatgagaact attatgacga actgatacaa agtaaaacaa
    38761 tccagtgttc gattatcaat ggaggagacg gaagcggaca gcatccaacc caatgcttgc
    38821 ttgatttgat gaccatttat gaagaatttg gtcattttga aggtctgaaa gttgccatcg
    38881 taggtgatat cactcactct cgcgtagcta aatccaatat gcagatgtta aaacgtctag
    38941 gcgcacaagt attcttctca ggtcctagag aatggtacga cgatgaattc gaagtgtacg
    39001 gacattatat gccattggat gaactactag atcaagttga tgtcatgatg atgcttcggg
    39061 tgcaacacga acgccatgat ggaaaagaaa gtttctcaaa agaaggctac catcaggaac
    39121 atgggttaac agttgagcgt gcgaagaagt tgcaaaaaca tgcaatcatt atgcacccag
    39181 caccagttaa ccgtgatgta gaattagctg attcattagt ggaaggatta cagtcgcgga
    39241 tcgttcagca aatgagcaat ggagtattcg tcagaatggc aatcttagaa gcagtgctaa
    39301 atggaaaagc gtaattatag gaggatgaaa aaatgaaaac actcattaaa aacggtcaga
    39361 tcaatacacg aaaaaatatg acgacaccag cagaaatttg gatagaagat gggcgaatca
    39421 aagcaatcgg tacaggattc tcagaagccg aatttgatga agtgtttgat gcaaagggac
    39481 aattgatcac acctggttta gtggacgtcc atgttcattt gagagagcca ggatttacat
    39541 acaaggagac gatcgaagct gggactcgct cagctgctcg tggcggtttc actactgtat
    39601 gcgcgatgcc gaatttaaat cctgtacctg atacggcaga aaagctgaga caagtatatg
    39661 acatcattag aaaagatgca gttgtgaagg tattgcagta tgcgccaatc acagaaaatc
    39721 tgcgaagtga gaaattagtt gatcaagaag cactgattga agaaggtgct tttgctttca
    39781 caaatgacgg tgtaggtgtc caaacagctg ggacgatgta tctggctatg aaagaagctg
    39841 caaaaaacaa taaagcccta gtagcccata cagaagatga atctttatta tttggcggcg
    39901 ttatgcacgc tggcaagaag gcagaagaac ttggtcttcc cgggatctta agcgtaaccg
    39961 agtcttctca aattgctaga gatctgttgc tagctgaagc aactggtgtt cattaccatg
    40021 tttgccatgt ttctactaaa gaaagtgtcc gtgtaatcag agacgcaaaa aaagcaggaa
    40081 tccacgtaac agcagaagtt tcaccccatc atcttatttt gatcgacgaa gatattcccg
    40141 aagatttcgg cttttggaaa atgaacccgc cgctaagagg acgggaggac agagaagctt
    40201 tgatcgaagg cttgcttgac ggtacgatcg attgcatcgc tacagaccat gccccccatg
    40261 gattagaaga aaaaagccaa agtttcatga aatcaccatt tggtatcgta ggaagcgaaa
    40321 cagcgtttca actgatctat actcattttg tagaaactgg tcgattcacg ttggaacaag
    40381 tgatcaattg gttggcagtt aaaccggctg agatttttgg tttgaatgca ggaacgctaa
    40441 cggttggtgc ccccgctgat gtagcagttt ttgatattac acaaacttgc acgatcgata
    40501 aagaagactt tttatcaaaa ggggagaata caccttttat cggctggaaa gtaaaaggcg
    40561 aaacacaaat gacttttgtc aacggaaaac ttgtgtggca gaagggagaa taaaagtatg
    40621 gaacgtttgc ttatattaga agatggaaca gttttcgaag gaaaggcttt tggtgcagat
    40681 gctagtgtct tcggagaaat cgtttttaca acaagtatga ctggttatca agaaactatc
    40741 actgatcaaa gttttaacgg tcaaatcatt acatttacct atcctatggt gggtaattat
    40801 ggggtaaata gagatgatta tgaatcgatt tctccaacat gcaaaggagt agtagtaaaa
    40861 gaacatgcac gtgtagcttc aaactggcga aaccaaatga cgctagattc atttttgaaa
    40921 caaaaaggaa ttcctggaat atcaggtatc gatacgcgcg cccttactcg caaaatccgt
    40981 gaagtcggaa cgatgaaagc tagtatagtt gatgctggag attccttcga acatgcattt
    41041 gatcagctga aagcaaccgt tctagcaacc aatcaagtgc agcaagtctc aactaacaaa
    41101 ccttatccaa gtccaggaac aggtcggaaa gtcattgtca ttgacttcgg cttgaaacat
    41161 agtattttac gagaattgag taaaagaaac tgtaacctca cagtacttcc ctataacaca
    41221 gatgccgaga cgattttagc gctatcacca gacggagtca tgctgacgaa tggacctggt
    41281 gatccaaaag atgtgccaga agcaatcgaa atgatcaaaa aaatccaagg aaaagtaccg
    41341 atttttggta tttgtctcgg tcaccagtta tttgctttag ccaacggtgc agatacctat
    41401 aaaatgaaat tcggacatcg aggattaaat cacccggtac gagaagtagc gaccggaaga
    41461 attgatttta cttctcaaaa tcatggctat gcagtcgatg aagccacgat tgatccagaa
    41521 aaactcatcg taactcatgt agaagtaaat gacggaacag tagaaggagt caaacacaga
    41581 gattatcccg ctttcagtgt gcagtttcat ccagatgctg cccctggtcc gcatgatgca
    41641 ctacatttat ttgatgaatt tatggaaatg atggacgcag gaaaggagca gtaaacagat
    41701 gccgaaacgt acagatatca agaaaattat ggtgattgga tctggtccga tcatcattgg
    41761 tcaagccgca gaatttgact acgcaggaac acaagcctgc cttgccttaa aagaagaagg
    41821 atatgaagtg gttttagtaa attctaatcc tgcgacgatc atgacggata aagaagtggc
    41881 agatcaagta tatatcgaac cgatcacact tgaatttgta tcaaggattc ttcgaaaaga
    41941 gcgtccagat gctctccttc caactttagg cggacagaca ggcctcaata tggcaatgga
    42001 gctggcagca tcaggtattt tagaagaatt gaacatagaa cttctaggaa caaagctttc
    42061 tgcgatcgat caagcagaag atcgtgatct attcaaacag ttgatgaaag aattgaatca
    42121 gccaatcccc gagtctgaaa tcgtcaatac agtagaagaa gctgtagatt ttgcaaataa
    42181 aatcggctat cctgtcatcg ttcgtccagc ctttacttta ggcggaactg gtggaggtat
    42241 gtgtgaaaat gaagaagaat tacgtatcgt atcagaaaat ggattaagtc tttcccccgc
    42301 tacccaatgt ttgattgaac gaagtattgc aggttttaaa gaaattgaat atgaagtgat
    42361 gagagattcg gctgataatg caatcgttgt ctgcaatatg gaaaattttg acccggtggg
    42421 tatccataca ggtgattcta tcgtatttgc ccctagtcaa acattgtctg accatgaata
    42481 tcaaatgctt cgtgatgctt ctctttcgat tattcgagca cttaagatcg agggaggctg
    42541 taatgtccaa ctcgctcttg atccacatag ttttaattat tatgtgattg aagtcaatcc
    42601 gcgtgtttct cgttcatctg cgttagcaag taaggcgact ggctatccga tcgctaagct
    42661 agctgctaaa atagcgcttg gattaacatt agacgaaatg aaaaatcctg ttacaggaac
    42721 gacttttgca gaatttgaac ctgcattaga ttatgttgta gctaaaattc ctcgctggcc
    42781 gtttgataag tttgaaaacg gagaacggct tttaggcacg cagatgaaag caactggtga
    42841 agtgatggct atcggtcgga atatcgaaga gtctttattg aaagctgtgc gttctttaga
    42901 aatcggtaca caccatatcg aacttcctga gttggcagac atcacggacg atgacctaat
    42961 ccaaaaagtg gttcgagcac aagatgatcg cctgttttat gtagctgaag ctattagaag
    43021 agggtacacc atagaagaat tagcggattt gacaaaaatc gatttattct ttttagataa
    43081 actgttgcat atcgtagaaa tcgaacagca gttgaaacag cagccgttgg atgacaagat
    43141 attgaaaaca gcgaaacaaa acggttttac agacaaaaaa gtggcggagc tgtgggaaat
    43201 aaacgaagaa gccgttcgcc agatgagaaa agaaaatgat ttgattcctg tatataagat
    43261 ggttgacact tgtgcagcgg aattcgaatc aaaaacacct tatttttata gttcctatga
    43321 atatgaaaat gaaagttcac gatcagaaaa gccctcaatt ctagtactgg gatctggtcc
    43381 tatccgtatc ggacaagggg ttgaatttga ctatgcgact gtgcattctg tcaaagcaat
    43441 ccagcaggca ggatacgaag caatcatcat gaacagcaat cctgaaacag tttcgactga
    43501 cttttctatt tcggataaat tatattttga gccattgacc ttcgaagatg tgatgaatgt
    43561 gatcgagcta gaacagccga taggagtaat cgttcaattt ggtggtcaga cagcaatcaa
    43621 cttagccgaa cctttgactg ctgctggtgt aaaaatctta gggacaacga tcgaagactt
    43681 ggatcgtgcg gaaaatcgtg atttattcga gcaagcgctg aaagagttgg atattcctca
    43741 acctttaggg gatactgcta caagtaaaga agaagccgtg gttatcgctt cgagaattgg
    43801 ttatccagtt cttgttcgtc caagctatgt attaggcgga cgtgcgatgg aaatcgttga
    43861 aaaccagcga gatttagaag attacatgga acatgctgtg aaagcatctc cagaacatcc
    43921 agtactagtg gaccgttact tgcttggtgg tgaatgcgaa gtggatgcga tttgtgacgg
    43981 tgaaacagta ctcatcccag ggatcatgga gcatattgag cgtgctggtg tccattcagg
    44041 ggattcaatg gctgtgtatc cacctcaaac attatctgaa tcgatcaaga aaacgatcga
    44101 agattacacg atccgcttag cattaggttt gaattgtgtc gggatgatga atatccagtt
    44161 tgtcatccat gaaaatgagg tttatgtgat cgaagtcaat cctcgagcaa gtcggactgt
    44221 tccattctta agtaaggtga caggaattcc aatggcacaa attgcgacga aagctatttt
    44281 gggagagaaa ctaaagacac ttggttatga aaacggactt tatccagaaa caaaagaagt
    44341 tcatgttaaa gcacctgtct tttcttttac gaaattgcag aaagttgata cttacttagg
    44401 gcctgaaatg aaatcgactg gagaagtaat gggatctgac agacaattag acaaagcttt
    44461 gtacaaggca ttcgaagctt ctggattaca cttgcctgaa tatggagccg tattatttac
    44521 gattgcggac gaaacaaaag aagaagcact agaattagct aaacgtttta cagaaattgg
    44581 ctatagtctg ataggaacga aacatacagc tgcttatttc gaaaaaaatg gtctggtcgt
    44641 tgaaacagta gcgaaaattt ctgaggaagc agcagaaaaa aatgtagtcg acttaataag
    44701 agatggtaaa acacaagtgg ttgtcaatac gattgataaa gatcggggaa atgcttctaa
    44761 agacggtttc atcatccgaa gagaagcagt tgaacatggt attccattgt ttacttcttt
    44821 agacacagca gatgcgatcg ttcgagtgat ggaatcccgt gctttttcaa ctaaccctat
    44881 ttaacggcga gcacatgtta agacaaaaag acgaaaaacc gttgcaggag gggacagatg
    44941 aaacaagaaa tgatggaaat cgttcagcaa aaacagctgg caccaaagat ttttgaaatg
    45001 acattgaaag gtgatctagt aaaagaaatg cagcaaccag gacagttctt gcatattctc
    45061 gtgccgcgtg cagacttgct attacgccga ccgattagct tgaatcatat cgaccacgaa
    45121 acaaatactt gccgtatcat ttatcgggtg gaaggtgagg ggactagagt cttctctact
    45181 ctttctgccg gagaccattt agatgtcatg ggtcctttag gcaatggttt tgatttgtcc
    45241 aatcttcata caggagacga agtatttata atcggtggag gaatcggtgt ccctcctcta
    45301 tatgagttat caaaacagtt agtcgaaaaa ggaattaagc caacgcattt tttaggtttt
    45361 gccacacatg aagtcgttta ttatgaaaaa gaatttaatc gtctaggaga aacaagaatc
    45421 gctactgacg atggaacata cggtatgcac ggaaatgtcg gtaatttatt gttaggaacg
    45481 aagacggaac ctacagctgt ttttgcatgt ggttcaaacg ggttattgaa gacagtggaa
    45541 cagctgtttt cttcgcatca aaatgtccag ttatcattag aatcccgcat ggcatgtggg
    45601 ataggggctt gctatgcttg cgtttgtcat acgccggaag atgaaacagg aacaaaaagt
    45661 gtgaaagttt gtgacgaagg accgattttt aaaataggag aggtaattat atgaatgaga
    45721 atcctttagc ggtcaaactt cctggcctag aattaaaaaa tcctatcatg ccggcaagcg
    45781 gctgtttcgg ttttggcaaa gaatacggaa aatactatga tttgaatcag cttggatcga
    45841 tcatggtcaa ggcaacgact ccaaatgccc gctttggcaa tcccacgcca agagtggcgg
    45901 aaacaccatc tggcatgttg aatgcaattg gtttgcaaaa tcctggtcta gacgttgtta
    45961 tgcataaact tcttccagaa ttagaggagt acaatgagtt acccatcatc gcaaatgttg
    46021 ctggtgcttg tgaagaagac tatgtagaag tttgtagcaa aattggcgaa gcaccaaatg
    46081 tgaaagcaat cgagctgaac atttcttgcc caaatgtcaa acatggcgga attgcttttg
    46141 gaacagattc tgatgttgct tttcaattaa cacaagcagt aaagaaagtt tcttctgttc
    46201 ctgtctatgt caaattgtcc ccaaatgtaa cagacatcgt tccaatcgct caggcaatcg
    46261 aagctggagg ggcagatggg tttacgatga tcaatactct tcttggtatg cggattgacc
    46321 ttaagacaag aaaaccgatt ttagccaatc aaacaggtgg actctccgga ccagcaatca
    46381 agcctgtcgc tattcgtttg attcaccaag tagcaagtat atccagcctt ccaatcattg
    46441 ggatgggcgg cgtgcagaca gtggatgatg ttcttgagat gtttatggct ggagcaagtg
    46501 ctgtagctat agggaccgcg aatttcaccg atccgtatat ctgtcctaaa ctaattaaag
    46561 agctccctgt gcgaatgagc gaactaggca tcgaatcgct ggaaagatta atcaaagaag
    46621 tgagagagga acgtgaacga tgaatcaact agaccaacga ccaattattg cattagattt
    46681 ttcaactagg caagaggtag aagactttct tcgatttttc ccgaaagaag aaaaattgtt
    46741 tgtgaaaatc ggaatggaat tgttctacca agaaggacct gaaatcgtac gttatctaaa
    46801 agaggctggt cataatgtat ttttagatct gaaacttcac gatattccga atacggtcga
    46861 aaaagcaatg cggggattgg caaagcttgg tgttgatctc acctgtgttc atgccgctgg
    46921 cggtattcgt atgatggagg cggcaatgcg aggattagaa gaggggactc cagaaggtgg
    46981 aaaacgtccg ctacttctag ctatcactca gcttacttct acaagtgaag aagaaatgca
    47041 tgccgatcaa ctaatcgaag tttctttaga aaaaagtgtg atccattatg ctagctgtgc
    47101 caaaaaagca ggattagatg gtgtggtttc ttctgcttgg gaagtagaag cgatcaaaga
    47161 aatggcagga gacgaatttg tttgcttaac tccgggtata agaccagaag gaacagtcgc
    47221 aggagatcag acaagagtag tcacaccttc tcaggcaaaa aagatcggct caacttttat
    47281 cgttataggt cgaccaatca ctcagtcaac taatccttat aaagcatatc aaacgattca
    47341 aacagaatgg agctaaccta aaatgaatgt tgaacaaagt atcgcaaaag acttattaga
    47401 aattgaagca gtatttttaa atccaagtaa tccttttaca tgggcaagtg gaatcaaaag
    47461 cccaatttac tgtgataacc gaatcacgat gagctatcca aaagtccgaa aagagatcgc
    47521 aaaaggatta gcaagcaaaa tcaaagaagc ttaccctgaa gtacaagtga ttgctggaac
    47581 tgcaacagca ggaatccctc atgccgcatg ggtagcggaa atactggatt tgccaatggt
    47641 ctatattcga agtaaggcga aagatcatgg gaaaggtaac caaatcgaag gacgtatatt
    47701 tgaaggtcag aagatggttg tgatcgagga tttgatttct acaggcggaa gtgtcttgga
    47761 agcagctgaa gcagcaaaaa gagaaggtgc ggatatcctt ggtgttgcgg ctatctttac
    47821 gtatgagttg ccaaaaggaa aagcaaattt cgaaaaagcc gaaatccctc ttatgacgtt
    47881 gaccaattat tctgtattga ttgaagcagc tttagaagat cgttatatcg atgagcaaga
    47941 attaactctg ctaaaagaat ggaaaaaaga tcctgaaaat tggcagattt aagcgcgctt
    48001 gatgaagata gagaaatccg atttgtgtct ccagaatcat caattggaat agcaaaaatc
    48061 caaaaactga ttgcgagaag catcttttca tcaggtatga aaagaaactt ctatcgtgat
    48121 cagtttttga tttttttaaa attcattttt ctaagactgg ttagcagaaa gaagagaata
    48181 atctcttctc ttttttctat tatatataga ttttctctat tttttggtaa gggagctgtt
    48241 tcaaaaatgg taaagagcgg aaatgttgcg aatatcagtt atttaatgat atgatattcg
    48301 gaaaaagaaa tctcaaaggg aggtaacttt tatggggttg aatgaattta ttttaggatt
    48361 gaacaattta gagacgatca caagggcacc tggatttttt aaatatacag agcatacagt
    48421 tgcagcacat tcgtatcgtg tagcatctat tgcgcaagtt ctaggagaca ttgaagaagc
    48481 gaatggacaa ccgatcgatt ggaaactgct ctatgaaaaa tcattgaatc atgactacac
    48541 agagcgtttt attggtgata tcaaaacgcc ggtgaaatac gcaagcaaag agttaagagg
    48601 gatgctgcaa acagttgaag aaaagatgac ggacgaattc atcaaccaag agattccagc
    48661 tgagttccaa gaagtttatc gccgtcggtt gttcgaagga aaagatgaaa ccgtagaagg
    48721 agaactatta gccatttcag ataaggttga ccttctttat gaatcttttg atgaaatcat
    48781 caaaaataac ccggaaaaag tttataagga gatgttcatt gaggcagtga ctacgattaa
    48841 aagctttgaa catcggcctt ctgttcagta tttctttaaa gagatatttc cggaactatt
    48901 gaaccaggaa ttttatggaa aagaggcgtt tttagaaacc gtctcaacga ttgtaaagaa
    48961 agaagaaaaa taaaaatgat atgagatgca gggggaagta tagttgaaaa agaatatgga
    49021 tgtcgaatgg ggctattctg gagacaaagg tccggaaaat tgggcgagtt tatgtgattg
    49081 gtttgcgaga ggtgcggaat ttccattgca gtcgcctatt catttgacca agggggaaga
    49141 aaccaaaata gaaggagaca cgctttcctt tcattatcaa aagcaacggt ttactgacaa
    49201 ggaattcaaa aacacgattc atttagtacc ttttgaccaa ctcagttatg tagagttcaa
    49261 gaaagaacgc tattatttga cagatattca tttccacttg ccttctgaac atatcatcaa
    49321 cggaaaacag gaagatattg aatttcattt tgttcatatg aacagcaaaa aagagaatct
    49381 agttgtgggt gtcatgtacc agctaatggt acaggaaggt tggctgtata atcaagaaaa
    49441 tggggaaagt tggaacttag aaaaacatga gcattgggta aatccggatg tgttctttcc
    49501 ggagcaaaaa agccatttcc attatattgg ctcattgaca actccgccta ccagcgggcc
    49561 aatccaatgg tttgtaatgg atcatgtagg aaaactgaac caagagtttc ttctcccctt
    49621 cgatggtcag tatgctcgac cgaacaaccg accaatccag cccttgaatg gaagagaaat
    49681 ttattatttc gaggagtttg agcaatgaat attcagcaga tgaaatacgt ggtcgctgta
    49741 gcaaacaatg gtagtttcag agaagcggca aagaaaatgt ttgtctccca gccaagtctt
    49801 tcagctggta tcaaagaatt agaaaccgag ttagggatca cgctgtttac tcgaacgaat
    49861 cgaggggcat atttaacaga agaagggcaa gacttcttaa atcgtgccga gaaaatattg
    49921 gtccagcttg atacattaga aactcactat ctaacgagtg aaaagagaga caatttttcg
    49981 atcgctgccc agcattatga tttcttaggt cctttgaccg cacagctact cgaggaattc
    50041 aaagacgaga tcaaacaatt tcggatcatg gagacgacaa cagcgagagt gatcgaagaa
    50101 gtcaaagagc agcacagtga gatcggcatt atttatatga atgagcataa tcaagctggt
    50161 atcagaagat atttacaaca aggagagcta agtggccgca gcattggaaa attcaaaacg
    50221 catatttttt taaggcaagg acatccatta gctgaacacg cagagatcac caaagaagaa
    50281 ttgttatctt atcctcaagt tcgttttaca caggatggaa ataatttccc gtatttttat
    50341 gaagacctta tcgagatccc tgatcaagaa acagtgattt atacgagtga tcgaggtact
    50401 ttgatgaata tcgttcttga aactgatgct tacgcttcag gatctggtat tgtgattgga
    50461 gggattcgcg agcacttgcg gttaatccct ttggcagaag gcgaactaaa tgaattttat
    50521 atcatttatt cggcgaaacg tccgctcagt gaaatcgctc aaagatttat caaagagctt
    50581 actcggttac tggaccagca gagctaagaa aagcagatga gaacgctgtt tattgaacac
    50641 cgttgatcaa aaaagagggg ttgtgacaga attttgtcac aactcctctt tttgtagcaa
    50701 acaatttata actaattgct gttgtgggaa agtacgcaaa tatgattcta gaaacactca
    50761 ttgattacct gttttgtttc atagctgtaa ttttttcttc ttctggtgtc acgataatcg
    50821 tcttttggtt ttcataaata acataaccag gcttggcgcc atttggtttt cggatatgct
    50881 ttacctgtac aagatcaacc ggcacttggg cagagtatcg gtattttgaa aaataggcag
    50941 ctaactcggc agcttctgta attgtttcat ctgagggctt gtcactttta atgatgacgt
    51001 gcgaaccggg tatatttttt gcatgaagcc aatagtcggt ttttttagct gtcttcattg
    51061 tcagctggtc attttgaaga ttgtttttac caacaagaat gagcgttccg tcagaagaaa
    51121 agtattgatc aggctgagat ggtttcttac gtttttgttt ttttaagttc ttctttttca
    51181 ggtatccttc tgaagtcaat tcttctttaa ttgcttcgat atccattggg ccggcaattt
    51241 ccagttgaga taagacagat tcaagatatt ggatttcatc tttggcttct tggatttgtt
    51301 cgccaatcag cttaacagcg ttcttcagct tttggtatcg atggaaatat ttctgtgcat
    51361 tttgatttgg tgtcaatgcc ggatctagtg ctattttgat tggccgatct tcttcataat
    51421 aattaggtaa aacaacttct tttgcgccgc gtggtacttg tgtcagaaaa gtagtaagta
    51481 gttcgccatt tctacggtaa ttctcagcgt tttcggattc tttgagtgtt tgttcacgtt
    51541 ttttcaattt atttttattt cgttttagtt cattttcgat ttttcgaatc agttctccgc
    51601 cttgttgttt tgcccgatct ttctctgctt tttcgtgata atagctatct aataattgac
    51661 tgagtgttgg ataagctgtt acagcagatg cctgttcgga caatacctga taagcaatcg
    51721 gtgtgaaaaa atctttattt tccgtttcgt aaaaagtagg aataggctga tggctgatgg
    51781 ctgagaaaaa ttcgtcccat acaaccatct tttcattagg acgttccagt aatcttttgg
    51841 tcagctcttg agcgatatcg aaaccgattc cctgaaactg acgttggatt gcttttggat
    51901 ctagttcagt ttgggaaagc cgctgaaaga ttttttcttt ctcggagcta aatgggttca
    51961 agacctcttg ttttggcgga gcaacatatt ctacaccagg aagcaaagaa cgataagtgt
    52021 tttgagagct tccaatgtgt ttgatcgcat ccagtatttt tccagtttct cgattaacta
    52081 agacgatcgt actatgacgt cccattaatt caacgatcaa tatgatattt tgtagatcac
    52141 ccaactcgtt tcgtttagca aagtggaaat ggatcactcg atcattttcg atttgttcga
    52201 tgtcttctaa aatagcgcca tccaaatatt ttcgaagcat catcacgaag ttaggcggat
    52261 tatcaggatt ctgataatcg atttgggtaa tctgtacacg agcataactt gggtgcgcag
    52321 ataataataa tcgatggttt ttgccgcgtg aacgaatcac cagcacgatt tcattttcat
    52381 aaggctgatg gattttcgag atccggccag atagtaacgt ttcacgcaat tcgttgacca
    52441 tcgcgtgggt aaatacacca tcaaaggaca tggttcattc ctcatttctt ttcataagta
    52501 tattcattat aacgaaaaaa agaagaaaaa ccaatttggc cgaatagtaa agcaaaagtc
    52561 tagaaaaatc ttggactaat tacataaaaa acagtgtttc tatcgttgaa atccaaattt
    52621 ttaggtataa taaaaaatag gagaaaaagt agaaaagaag gtgtttgtta tttgggaagt
    52681 agttaaatcg agagtacaag aaatgaatga acatttctca gtgtcattcg cagaaaatcc
    52741 aagtaagtat tttcgacgtc ttgtttttct gctcatctta tcattgctgt taacagttgc
    52801 aatgttttta ttgccggaaa aaatccgaga agagcaagta aatagtctcg tttattcgtc
    52861 cataccaacc agcaaattga aaccttttga ttacagcaaa gctgatcaga aaatcaaaca
    52921 aagccgggcg atatcggtga tgttcagcaa accgaacggg aaaacctatc aggacatgct
    52981 tgatgttttt aatgatcctg agcttatgga agaattgaat cgaccgatct tttattatcc
    53041 gatcgtttat gatgtacatg aactggaaca aaaatataac atacgaacgg atgaagtgac
    53101 atttattttc tttgatggag gaaaagaagc aaatcggata actgcgggta agggaggaat
    53161 aactgatttt gataaggagt tgatccctga actgaatcga cttccgttag ccaatatcaa
    53221 acaattagaa gaagaattgg atagaacggg agtaacttcc caaaattccg agattgctaa
    53281 ttgagacatt ggcgcgatga aacggtgggt ctatatagcg ctatttttaa ttatcagaac
    53341 aagtgatgtt tgatcttcaa aataacaaat aaaaaattaa aaaatatagt tgacgaaatt
    53401 caaaaattcg attagactta aatcaattct taaggaaagg gtgacctgta atgaacttat
    53461 caaaacgtat ttcagcagaa aacaaaaaaa attggcgcag ctggcgtaga taagttgtat
    53521 taatggtgag actttcccat agatacaact ttttagagtg catttctaaa gcttgtatct
    53581 atgctagaca tgaacattga ctgccgcata gattagaatc tatgcggttt tttgtgtaaa
    53641 gacaatgacc gctttggcca ttgtcttttt ttgtagactg gatacttgcc tgattataat
    53701 aaataaaaag attgactttg caggaggaaa aaaatgaaaa acaaacgatt aataacagtt
    53761 gtagtaatta ttttagttta tttagcaggt gcatttattt atggaaaagc ctcaggcgaa
    53821 aaagaaagta cttcgacgaa ccagacaaaa aaaacaacag ttgttggggt attgcaatac
    53881 gtgagccatc cggcattaga tgagatttat cgaggaatca aagatggtct gaaagaagaa
    53941 ggattaaaag aaggagaaaa tcttgagatc aaatttcaaa atggacaagc cgatcagagc
    54001 aagctagcca caatgagtca acagctagta caatctgatc cagatgcctt gattggaatc
    54061 gcaacacctg ccgctcaatc attagcaaac acgacttcat cgatcccagt tgtgttaggt
    54121 gctgtaacgg atcctgtggg ggctggatta gtcgcttctt tagagaaacc tggtggtaat
    54181 gtaacaggtg tttctgatca gccgcctgtt acttcacaaa tcaagcttgc ttctgatttg
    54241 ttgccaaatg caaaaaaagt cggaatcttg tatgcttctt cagaggataa ttcaaaatac
    54301 caagtagcac aagcagaaga agctgcaaaa aaagaagggt tagaatcagt aaaatatgcg
    54361 gtgccttcca ctaatgagat tgcacaaacg gttcaagtga tgagccgaca agtcgatttt
    54421 atctatgttc cattagataa taccattgcc aatgcgatgc aaacagtggt aaaagaagca
    54481 aacaaagcaa atatccccgt cattccatct gtggatacaa tggtggaaca aggtggacta
    54541 gcaacaatcg ggatcaatca atatcaatta gggcttcaaa gcggtaagat ggcggcagaa
    54601 cttgcgagtg gaaaagaaaa accggaaacg acgcctgttt atacatttga tcaaggggat
    54661 acagtgatca atcaatctca agctgatcgc ttaggaatca ttgttcccca atcgatgaag
    54721 gaaaaagcca aaatcattac agatgactcg cagcaagaaa catctaagga ggatgacaaa
    54781 tgatcgtatc agctatttca caaggcatgc tttgggcaat attaggatta gggattttca
    54841 tgacttatcg gatcttagac tttcctgata tgacgacaga agggtccttc ccattaggtg
    54901 ctgctgtctg tgtgacagct attactcatg gggtagcgcc gattgtagct acattattag
    54961 gcgtaggtgc tggcatgata gcaggactcg ttacggggtt actttataca aaaggaaaga
    55021 taccggttat tttagcaggg attttagtga tgtcaggatt gaactcagtt attttgtttg
    55081 tgatgcgaac accaaatctt tctttattga atcatccgat tctacaagac agcttccatc
    55141 gctttgggtt acctgattac tttgacacag tccttcttgg cttcatctct ttgggcatct
    55201 tgattgctgt actgctattc ttcttcaata cagatttggg tcaaggctat attgcgacag
    55261 gagacaacga aacgatggct cggtcgttag ggataaaaac cgatcgtatg aaaattttag
    55321 gtttaacttt gtcgaacggt gtcattgcat tatccggtgc gctgattgcc cagaacgacg
    55381 gatatgcaga tgtaaataaa gggattggcg taatcgtcat cggtcttgct tccatcatca
    55441 tcggtgaagt gatcttccaa gaattgacgc tagcagaaag attgattgct attgttgtcg
    55501 gcagtatcat ttatcagcta ttgattttag tagtaatcaa actagggttt gacacgactt
    55561 atctgaagtt gttctccgct atcatcttag ctatttgtct gatgatcccg caattgaaga
    55621 aagcactgaa cttaaaaacg ggttttgaga aggaggcata gtaatgactg atatattgac
    55681 aatcaaaaat ggcagaaaag tcgtaaacaa tggaatgaat gaagagaaag tactattgga
    55741 tgaaattaac cttacaatca gagaagggga cttcatcact gtccttggcg ggaatggtgc
    55801 tggaaaaagc acactgttca atacgatcgc tggtacgctt caactcagtc aaggatcgat
    55861 ctcttttaaa gatcagctga tcacaaaaga ttcagaagaa aaaagagcac gattcctttc
    55921 tcgagttttc caagacccca agatgggaac ggctcctcgg atgacagtag cagaaaattt
    55981 gctacttgca caaaaaagag gtcaaaaacg gaaattccgt ttacgtaact tgaaaaatca
    56041 aaaagaagat tttttcagac tatgtcaaga agtcggtaat ggcctagagc aacacttgga
    56101 tactccagcg ggtgaattat ctggtggtca acgccaagca ttaagcttgc tgatggcgac
    56161 gatcacagct cctgagttac tattattaga tgaacatact gcagctttag atcctaaaac
    56221 agctaaagca ttaatgcgat taacaaatca gcggatcaat gaacaaaaat tgacttgtct
    56281 catgatcacg catcgaatgg aagacgcctt gaaatacgga aatcgtctga tcgtactcca
    56341 aaaagggaaa atcgttcaag atatttctga aaaagaaaag caacatttga caatgggcga
    56401 ccttttgcag ttctttgaag aagtagtgga ttgatttcga cagaaaaatt cctttcagta
    56461 gaaggacttg aaaactcatt gacatcttcc tttgattcat cctatactta aaacaataaa
    56521 caattaaaca tatttgggtg ttttgtagga tcacgtagtc aatgatttta acaattaaat
    56581 agaatattct ttgctctgac aagtaaacga tgagaaaaga atttgctact ttgccaccta
    56641 gacgtttcgt actttttcgt atcaaacgct aagtggcttt ttttattgaa gtaagaacaa
    56701 aggaggaata agatgatttc tggacaaacc aaattagctg ggctctttgc tgatccggct
    56761 tctcacagtt tatccccatt gatgcacaat actgcttttg aagcaaacaa catcgatgcg
    56821 gtgtatttag ctttccaagt aaatccaatg aatttgaagc aagcagtcga aagtattcga
    56881 acttttgata tgttaggtgt aaatctttcg atgccgaata aaacagcggt tattccttat
    56941 ctggatgagg taagccagga agcgcaattg atcggagcag tgaatacgat cgtgcacgaa
    57001 aagggtcgtt tgattggcta taatactgat ggtgcgggct tcatgcaatc cgtgcaagaa
    57061 gctgggattt cgatcaaaaa gaaaaaaatg actctactgg gagctggagg tgcagcaaag
    57121 gcagtcactg ttcaagcagc gttagacggc gctgaggaaa tcgtagttta taaacgaaac
    57181 aaccaaacat tcgctcaagt aaaagaaaca ttcgaacaac tcagctatcg aacttcttgt
    57241 aagataaaag ttcgtgactt tgccgatacg catcaattaa gaaaagactt gaaagaaagc
    57301 tgtcttctag tcaatgcaac agatatcggg atgggaaaga aaatcaatca gtcaccgctc
    57361 ttagatataa gcatgatgca tgagaatcta gcggtttttg atttgattta tgcacctaga
    57421 gaaacacgtt tattaaaaga agcaaaaaaa gtaggagcaa aaggatacaa tggacttggc
    57481 atgttgatct accaaggagc aatcgcgttt gaattatgga caaaggaaaa gatgccgatc
    57541 catgtgattg aaaagctgtt tgattaaaaa aggataatag ataaagatct tttattctcg
    57601 cataaacggt ctcaagaaaa gtaatccttt atgtatcgaa gcatttattt cgttattttt
    57661 tattaaatta tcaaaaaatg ataggctttt gtcgattggt tatcgtatcc tttatttatc
    57721 agtaagaaac gaggaggaac cacaatgagt cggatggatc gctataagga catccataag
    57781 aaggcgaaac ctctgaagcg ggatacgggg agtatttttg ctagaagaga acgaaaacga
    57841 acgcgtatgg aaaatgagga agatgctacc cgtatttatg aaagagagca gcattcattt
    57901 gaacatttga accaatacga gcaacagata tacagagatg caccaagagc agaagaacaa
    57961 caaaaaaata aaaaattttt caatcggcaa aagaagaaca aaccgttaaa acctcgaaga
    58021 aagcgatcgt ggaaaaaaat cattctatcg attttgcttg ttttgatcct ttattcaggt
    58081 atctcatttt ttattggtaa atatgtagct gaacatgaca caagcttaga ggcagcgact
    58141 tcagaaacct ttcatgggca aaaagcgacg aatggtgcgc ataatatttt gatccttgga
    58201 agtgatacac gcggagaaga tgccgggcga gccgatacga tcatggtctt acagttggat
    58261 ggtccttccc ataagccgaa actgatttct tttatgcgtg acagcttcgt tacgatccca
    58321 ggggtaggac aaaataagat caattcagct tatgcatacg gaggagccga tctagtgcgt
    58381 caaactttag tagaaaattt tggaatcgat tgtcaatact atgcgaaagt cgatttcaaa
    58441 tcgtttgaaa aagtgatcga tgccttattc atgaacggag tgaagatcga tgcagaaaaa
    58501 gatctgaatc tggatggtgt agatattaaa aaagggggcc agaagatgga tggacatgtt
    58561 cttttgcagt acgcacgttt ccgaatggat gaacaaggag actttggccg tgtcagacgc
    58621 caacagcaag taatgaacgc tattttcagc caattgaaga atccattgaa tctgatccgt
    58681 gcaccttatg cagctggtaa agctttagga tatacatcca cagatgtcac tgcttggttc
    58741 ttgacgaaaa acctcttttc gattgcacga ggagctggtg gcattgatcg aataagtgtg
    58801 ccagtagacg gttcgtggaa ttatgggcaa agtgattatg ctggcagtat tcttgaaatt
    58861 gataatcaaa tgaatcaatc tgctattaca gattttttga ataaatgatc ataaaaaaga
    58921 tcaagaagaa gctgcgcaag gcttttgtca tgaatcaatc aaacgattca ctcgtaaaaa
    58981 acgctttctt atggtagatt taaccaagag aggagctgtt tacattggat atctatctga
    59041 acttcaaaaa tgagtcgcgt gaagccatcg ctttttatga aaaagttttt cagactgaag
    59101 catcaggtat caccacatac ggtgaaatgc ctggaataga acaaatgaac ttgccagaag
    59161 aagcaaaaaa tctaatcacg aatgcacggc tgaacattta tgatacatta gttatgtttg
    59221 cagatacgcc agaaggaatt ggtcctgaat tagttgtggg aaataatgtt tctttagtca
    59281 tccagacaag aaatgaagaa gaaacgaagc gcctatttga aagcttagct gagggtggta
    59341 agattgagat gccactggat gctgttccgt gggctcagtt gtatgggatg gtaactgatc
    59401 gatttggcat caactggcag attaaccaag agtgacagct aaagatgaat attttctgga
    59461 aacatcaagc agcaaacgga tcatcgtttg tttgcttgat gtttttgtgt ctatttcgac
    59521 tatacggtat ctttttttta ttgccagatg cgaaaatatg ttccataata gagaagtccg
    59581 caaaaaatta agtaacggag gtcagaagat gaagacggtg atactagctg aaaaaccttc
    59641 acaagcaaaa gcctatgccg aaaccttcca acagcaaaag cggcatgaag ggtattatga
    59701 aatcagcgat ccattgtttg ctggtgaagt aaccatcact tatggttttg gacatttggt
    59761 agatatggtt gctccaggag cttatgaaga gcgttgggca aaatggtctt tagaaaattt
    59821 gcctattttc ccagaaacct tccgttacga agttccaatg gacaaacgtg cacaattttc
    59881 gatcgtaaaa cgagaattgc agtcagccga taccatcatt attgcaacag atggtgatcg
    59941 agaaggtgaa gccatcgcgt ggtcgattat tcgacaagca aacgcatttt ctaaggaaaa
    60001 gaactattta cgtttatgga tcaattctct tgaaaaagaa gcaatctatg aaggttttaa
    60061 gaatctccaa cctggaaaga actattttcc aaaatataaa gaagcgcaag caaggcagaa
    60121 cgctgattgg ctgattggaa tgaatggaag tccattatat agcttgctac ttcaacgaaa
    60181 agggattgat ggcagttttt ctcttggtcg tgtacaaaca ccgacactct atatgattta
    60241 tcagctgcaa gaagaaatca aacacttcaa aaaagaaacg tactttgaag gagaaggttt
    60301 aattacgaca aacaaagggc agttttctgg aaaaatcgta ccaaaaaaag catttaaaac
    60361 ccaagaagag ttaacgaagg aaatagaaaa acttggagcg catttaggta agcaaaacgg
    60421 acggattctt gaagttacga aaaaggaaaa gaggttgcat agtccacgtt tattttcgct
    60481 atctagtttg cagacaaaga tgaatcagct aatgaaagca agtgccaaag ctacacttga
    60541 tgctgctcaa ggattgtacg aaagcaagtt tctaagctat ccaagaacgg attcctttta
    60601 cattacagaa aatgagcatc agtatctggt taaacatctg caaaattata aaaaattttt
    60661 aggaatagaa gaagtacaga caactgagat caaagcaaag aaacgatatg tcgatgcgaa
    60721 aaaagttcaa gaacatcatg caattattcc gacaaagacg attccgactc ctgcacgctt
    60781 tgcgaagctt tccaaattac agcaagcaat ctatttgcaa gttttgcgca ctactgtggc
    60841 tatgtttgct gcagattata tctacgaaga gacgaccgta atgacgggcg tacagcaatt
    60901 aaagctaaaa agcatcggaa agatcccatt acagcaaggt tggcaggaaa tcttacgcat
    60961 caagtcaaaa aagaaagaag ctcagactct tcctcctatc gtagaaaatg aagaagcaga
    61021 agtagaactg aaaagtatgg agaaagaaac acaacctcca aaaccctata ccgaaggaac
    61081 gttgatcaca gcaatgaaaa ctgcgggaaa aacgctggat aatgatgaag cgcaagaaat
    61141 tctcaaagaa gtagaaggaa tagggacaga agctacacga gccaatatca ttgaaaatct
    61201 taagcagaag cattacatcg aagtcaataa aaacgaaata actgttacgc caaaaggaat
    61261 cactctttgt aaggcagtag ccaatgaacc attactgacg agcgcagaaa tgactgcgcg
    61321 ctgggaaggg tacttgagaa aaattggtaa acaagagggg acaccatctg tttttttaga
    61381 gaatatcaaa aaattcatcc tacatttatt ggcagaagtt cctaatcaaa tcgacaaggt
    61441 agacttttca gatgagatta gcgggacacg tcagataaaa gcgatggaga agaaaaacga
    61501 tcaattagga agatgtccaa aatgtaaaaa gggaatagtc atgctttatc ctaaaatcgc
    61561 tacatgcttg aatccggaat gcgacttcaa attgtggcca acagtagcta aaaagaagct
    61621 gactaaaacg aatctcagag atttgctttc aaaaggaaag acaagtaaag ttgtcaaagg
    61681 ttttactggt aaaaaaggga aattcgatgc agttttagta ttaaaagaag atatgacaat
    61741 cggtttttct tttccatgga tcgaaaacag tggaacaaaa gcagttgatg gaaacaaaga
    61801 aacatcaaga aaaaataatg aaaacgaagt agagtaaatg aaaacaatga aatagcggaa
    61861 tatttattcc gaaaagtgag aatatagcaa tcacgattgt ggctgtgtac caagcatttc
    61921 taaagtatcc tgattacggg acgaagttgt tgtcattgac gcacaatcaa acagcatatt
    61981 caccaacgtt gattttatcg actttgactg caggagctaa aagcgctact tatttttttc
    62041 ataaaacgac aagcatgcta aagcgaaaga aacagcgaaa acaattgttg gtggtggtag
    62101 cggctatgat cattatttat tttctaccag ttattacaca agtatttcat caatattttg
    62161 gttaagaata cgagagtttg tgacaaaagt catgtcacaa acttttttct ttgtcatttt
    62221 ttcgtaagaa aaagcaaaat aaaagtatat acattgatta aaagtatata cttggatata
    62281 atgtacttac tatagaatga gaatggtata gagggtggcg aaatatgaaa aaaatgaaaa
    62341 agtataaaat tagaaaatct ggcaatagcg atgtaacaac tatcccacca gaagtaaaag
    62401 aattcatggg tgtgcagaca ggtgacgcaa tcagttatgt ttttcaatct gatggttctg
    62461 tacgaatgat caaagcacaa gaagaacctg atattgattc attagttgat tcgatcatga
    62521 atcaatatga agacgcgtta aaagatttgg ttgatttatg aggtatcttt cgactaaaga
    62581 aattatcaaa atcaacgcga aagttatttt accgtcactc gccaggcgaa atgatcggtg
    62641 taaaagatgc aaatgcatta gatatggccg tcaaacagcc ttcacaagca gtattcaatc
    62701 aagaactcta tcctgaaatc tatgaaaaag cggcgatttt agcaattaat ttagctaaaa
    62761 aacatccttt tcataatggc aataaacgaa ctgctcttgt tgccatgttg ttgtttcttc
    62821 aattgaataa ttgtccagtt gctttttctc gtcaagaagc tgttgatttt atcataatga
    62881 ttaccactag ttcattggat ttcgattcac taaagtccaa gataaccagt tatttacgac
    62941 aaaccgcaat aaaatgaacg aattaaaaac tttatttctc aattagatca gcatgtcatt
    63001 aaggaatatg ctgatttttt tatgtttaat catacaaaat agttttttca taaaaatatg
    63061 gaaaatatgg attaattttg aaataattga tttaaaagga atacaaaaga gtgaatagta
    63121 ggaaatagtg gtttagaact agtgggctga ttttttatat attttagttt acataatata
    63181 tattatacaa agtagattta aaaaatgata aacctctctc gaacggtttt ttatcaaaaa
    63241 tcgtcatttt tccatcaaaa tctgcttatg caaaattata aaaaaatttt gcagtttttc
    63301 ttactttttt tgtcgtttaa ttgaatgata aaaaccagtt tctttattca gttaatcaaa
    63361 tatgaacgaa ttagatatga atcattgtat ttgccgttgc ggaaggattt tttaattaac
    63421 cacagataaa cattgataac gattcgctta ttgtaatcaa cagattaaat ttcatatgtt
    63481 catatgtacg gatacatttt cggaccgatt aattttaacc attctgttta tttgcttacc
    63541 tattagatat caataaaaaa ctgcttaaca gctatttcag ctgttaagca gttttaggat
    63601 ttttagttca tattcattgt ttcttataat acagtgttca atacttctct taaagcactt
    63661 gttgatttgc tgaacattgc tttttcttct tcgttgattg ataattcaac aacttcacga
    63721 acaccatttt cgtcaacgat tgatggcaca cctgtaaaga tatctttttc gtcgtattca
    63781 ccagttaaat aagcagatac aggcaataca gcttgttcgt tattcaagat agcttttacg
    63841 atacgtgcag tactcatacc aataccatag taagttgctt ttttacgatc aatgatctca
    63901 taagcagcat tacggacttt atcagcaatc acatctaatt catcttgggc aatacgatgg
    63961 tctttttcta caatttcaaa cactggttta ccaccgacag ttgtatgtga ccatgcagca
    64021 acttctgaat caccatgttc acctaagata tagccgtgga cgctgcgtgg gtcaactttt
    64081 aatttcaatg cgatttcttt acggaaacga gttgtatcca atgttgttcc agtaccgata
    64141 acacgtgatg ttggcagacc agattcgttc caagcgatat atgtcaaaat atctactggg
    64201 tttgaagcaa caacgataat accgtcgaat cctgatccca tgatttcttt tacgatttgg
    64261 cgcatgattg acgcatttgt tttaactaaa tctaaacgag attgaccagg tttttggttg
    64321 ataccagctg tgataacaac gatatcagca tctttacatt cttcatagcc acctgaccat
    64381 acagccacat tttcatcgcc ccaagccata ccatctaaaa ggtccaatgc ttccccttct
    64441 gctttttctt gattcacatc gatcaatact aattcattag agattccttg gttgatcatt
    64501 gcataagcga tacttgttcc aacaaaacct gtaccgacga ttactacttt acgacttgtt
    64561 tttttcatga ataaacagct ccttttcata actatttgtt actttcatga aaagtatagt
    64621 cttgtttatt cattttatca acatgttaat tataatagtt gttattataa tttttgatgg
    64681 aaacgaattc ctgaatacgc ataacagata aatgacaaat gtttacacct atatcccctg
    64741 ataatacaac caaaagttta gaactgaaaa taaatccaaa aaaattcgct gcaacgatat
    64801 aataagacag caatcgcacc taaaacaatt ttccttcata tgctttagtg aaagattttc
    64861 ttcttaatgt ttatttctcc attcattggg agtacatgtt gaatacttct tgaataattt
    64921 gaataaagaa gtcgtttgtt tatatccgat acgattagcg atttcttcca acgaaaaact
    64981 cgtttcttga atcagttcca acgcaaagtc gaattttttc tttagaacca gttcttgaaa
    65041 ggaagcatca aaatacattt tcaatttatt actaagatag accggattgt agccaaaatg
    65101 agctgctgtt tcttttaacg tacaagaagt aaaatgctta tcgatataat ctaatactct
    65161 aagcatctca ttttctgcgc atccatctgc tgatgaaaag ctttgttgtt ctaataaatg
    65221 agtcaattcg atcagtaata gtgatgtata gagatttaac gaacggatct tatgactgta
    65281 tgtatcaaaa taaatcaaca gcatattttc aatcaaatgc gtcaaacgac ttgtttttcc
    65341 gccgcgaaaa tgaatgaatt gtgtatgttc ccctttttct tttgatgcat ttatcaaaaa
    65401 agaagaaagt agattatttg tgcttgccaa atgattcaat atctctgtag ataaggtttc
    65461 ttcttttaat aagatgttga ttaaaatatc ctcttgccct gtgtattcga ttctttgagt
    65521 agcttcttta tcaatgatca ccacgtcact ttcttccatc tctatccttt ctccattaat
    65581 aatttgtaaa catgtaccgc tatacatata attgatttca acaaaatcat gtgtatgctc
    65641 gggaacttcc gcatatcgac ggtgtttact gatatgaata tttccctgtt gaaatagatc
    65701 ccctcggtgg atttttggcg gtgtctgaag atggtaagct aagtttaaat cattgatatt
    65761 cattccttgt tcacgctgca gagtttcgat tgattcttcg ttacgcaaaa aaaatgtcta
    65821 attcagctag ttccaattga ctccctcctt tttgtaagcg gtttctttcg cttattagtt
    65881 cacgctgtac tgctattata tgcaaagcta tttttggttt cataaagact ttctatggtt
    65941 gggacatgaa cttcctgtga ttccgctatt gagagaataa ccacttcata ctatattttt
    66001 gataagcgct tacaaaaatg aaaggaacat gcttatgaat aaaaagatga tgaaattttc
    66061 tctgctgtca gtctctctta ttttgacttc tgctggtgca gtcacgtctg caattcccag
    66121 tatgtcagct acttatgcca cgcgttcttt atctgctgtt gaattattaa cgactgctcc
    66181 ctcttttatg gtcactattt ttgttttgat tagtagtttt attgctagga aaatcggaca
    66241 aaaacaaact gtgatcatcg gattagtgat tgcatcgatt tgtggtatcc tccccctctt
    66301 ctcacaaagt tacagtattg tcttagcttc aagagctgga ctaggtattg gctttggatt
    66361 gatcaattct ttggcagtca gcatgattgc tgccttttat cacggagatg aacgagcctc
    66421 tatgattggt tttcaaagtg catttcaagg atttggtgca gctttaatga catttgttgc
    66481 aggacagcta gtacagttcg gttggcaata taccttttta gtctacgcca tcagcttacc
    66541 tattcttgtc ttgtttgttt tgtttgttcc tacacctgaa acaactgaac ttcaatcgca
    66601 tggcacagcc ccaacaagac aagtaatcaa aacgaatcct aaaatgatta gttatggtat
    66661 ttttctcttg ctggtcatcg tggtatataa tgctgtatcg attaaattag ccacagtcct
    66721 gacgacttat tctctaggaa acgaaactaa tgcagcgaat atcttaacaa tcatgcaatt
    66781 ggcaagtatg gctgccggag tttgttttgg ctggcttcag acaaaagcac atcgctatat
    66841 gcttacactt tctttactac tgatgggaat cggctttgta ttgattgcca ctgtgataaa
    66901 cctgtatgtg attgggtttg gtgcgatcct aacaggaatt tctttttcgt tattcattcc
    66961 ttacttattc aaccaagtaa gtatccaagc gcccaagtac gcggagagtt tcaatacttc
    67021 aatcttattg gttggcgcta atttaggtac tttcattgca ccatatggtt tgctctttct
    67081 ctcttttgct tctcttggga gtaaaacact tgctgttttc gtcaatggca gtatcttgct
    67141 gttgattagc gcgcttatta gccttctagt agtacacagg acgaatagaa agacagtgat
    67201 aagagtagat gaagaaataa aagaacaatt gacaacaaaa taaatttgat ggaggtcgtg
    67261 taaaatgaca aatgaaaaac ataaagatag atggctttgg tatcctggag actttgagat
    67321 ccgccatgga ctgctacaaa atttccaacg ggaagaacga ggttttgact ggccagcgta
    67381 ctggtacatg gatgattgcc atcggaacgt caagtttaag agatattact ttcttgatca
    67441 accttccatg tttaaagtga cgatccaagg agttgggtat gtagaaatta atggacaaaa
    67501 acatccatgt ggaaaatggc tgacttgtcc agctggtaaa gcaaaaattc gtatctttgt
    67561 aggacataca tcagggctac cagcgatgtt tatcgaggga gacgaagtaa aatcagatat
    67621 tggctggaca gcaagtaatt ttattgaaga atatccagct ggctggagtc cgctttatgt
    67681 cgatatcgca aaagatccaa atcaaatcta ttatcaaaaa gaatgcgtcc atccagtcac
    67741 tgaaacggag attggcggag gaatcttatt cgattttggg cgagcagtga atggctgtgt
    67801 agaactaata tctctggatg accatatcga atctatcact ctatgttatg gagagtccga
    67861 tgtagaagct atggatatcg attattgcta ctataagcaa ataggaatga caagaaaaat
    67921 gaaagctcgt aaacgcgctt ttcgctattt gtttatacca gaggtttcta ctggaatggt
    67981 tcaacttcaa gtttttcatg aatttttatc tctttcgaaa caagctgctt tttcaagcga
    68041 ttcttcttta ctgaatcaga tctggtcagt atcagaagaa gccttcaagt tatgtagtga
    68101 tttgtttttt atcgacggta tcaaacgaga tcgctggatt tggtctggag atgcgtatca
    68161 atcattcatg atcaatcaat atcttttttt tgacgaggaa atcaataaac gaacgatatt
    68221 agcattaaga ggacaaaatg aaatcaagca gcatatgaat actatcgttg actattcgat
    68281 cttgtggttg attggtatcg aaaaccacta tatgatgacg aaagactatg aatttttacg
    68341 catcgtctac cctaagatgc aatcattaat gagatacttg atggagcaaa cgaatgaatt
    68401 agggtttatt tatgggagag caaaagattg gatatttatt gattggtctg aaatggataa
    68461 agaaggaacg cttgctgcag aacaagtctt attactgaaa gcctatcatt ccatgatcac
    68521 ttgcggagat atcttagctg aaacatatgg agagaacgaa aattatcata ctcatctcta
    68581 tcaagaaaaa tatcaactat tgaaacaaaa cctatttgac tacttttggg atgaagaact
    68641 tggcgctttt atcgattgct atgaatctgg gagaagaaat gtgacgcgtc atgcgaatat
    68701 tttcgctgtt ttattcgatt ttgctaacaa agaccaacag caatcgatct taaagaatgt
    68761 cttattgaat gacactatca cacagattac tactccatat ttcaaattct atgaacaaga
    68821 tgctttatgc aaactcggac agacgaatat cgtctaccaa acgattcttg attattgggg
    68881 agggatgtta tctcatgatg cggtaacttt ctgggaagaa tacgacccta ctcaaacagg
    68941 aaatgaaaag tacagtatgt atggagatcc ttatggaaaa agcttatgcc atgcatgggg
    69001 agcaagccca atctatcttt taggacgcta ttttatcggt ttgtatccaa caaagccagg
    69061 ttatgaagaa tttatgatac aacctaatct agattcattt gaaacactga attgtacgct
    69121 acctatcaaa gatggaaaga tttcgcttga aaaaacaaaa gataagatcg tgattacttc
    69181 tgatagaaca ggcggaacag tgaaaatgaa tggtaaaagt tatcctcttc tagcaaaaca
    69241 gccacttgtc ttaacaagct attcaaaaat aaatgcataa aacaaaaaac tgcttgcgac
    69301 atatcagaag actttaaatc ttcttctgat attgtccaag caatttttat tttgaagttt
    69361 gcttaattct gttctttaga aacaatgttt gttctttttc cggcaaaaag aaagctagat
    69421 aatacgacaa gtaaaaagaa agcgatgatt ccaactgtca aggctatttg accgtattct
    69481 cctagtttcc caagtacaag tcctggtact agataatcag tatcggcaaa tgtagaagaa
    69541 gcgattttaa gatctcctaa tactggaagg ataaataatg gcagccaact aatcaataag
    69601 ctattgaaag cagaacctaa taccgcccct cttctaccgc cagtcgagtt gccgaagaca
    69661 ccagaagcag ctccgcagaa gaaatgtcct actaccccag gaatgataac tgtagtttgc
    69721 aagcctatca tagcaaacat ggatagtgtt cctacaaaga agctaacaaa aaagccaatt
    69781 aatacagcat taggtgcata tggaaaaacg ataggaacat ctaatgctgg tttagaatcg
    69841 ggtacgagtt ttttagcaat cccttggaat gctggaacga tttctgccaa caccattcga
    69901 accccttgaa ggacgataac aaacccagct gtgaatgttc cagcttggat cagtgcaaag
    69961 attacagcgt tgtctccatt gcttagttct ctttcaacaa atccaggacc agctaacaaa
    70021 gcaagtgcga catatacgat cgacatcaag agcatgatcg atacagtaga atctcgcaaa
    70081 aagctgaaac ttttaggaat ctttatgtcc tctgtagaac ggtctttgtt tccaaaaaac
    70141 tttccgatcc atccactaga agcataaccg atatttccgg tatgccctaa cgcaacttga
    70201 ttgtttccag tgatgttctt cataaacggt tgacaaagag caggcgtaat agttaatagt
    70261 gttccttcga agaccccgcc taataagatc atccacaaat ttgcagtaaa ccccgcgctt
    70321 actaaaatga ctgctgttag acaagaaaca taaagcattg cttgacctgt aagaaaaatg
    70381 aatttatatc ttgtgaatct agcaagtaaa atattcacga tcatccctac tagcatgatc
    70441 aaagcagtag gtgtaccgta ttgttgcaaa gcaatcgcca ctactgcttc attgctagga
    70501 actactcctt gagtatgcag agctgtttgg aacatcgaag caaaaggggt tagtgaatta
    70561 ctgattaaac cagcaccgcc gatcagtact aggaatccga caaatgtttt gatagttcct
    70621 tggatcactt ctgaaaattt cttcttctga agaacgagac caagcagtgc aatcaaagaa
    70681 acgaggatgg agggctgact gacgattgac acaaacaaat tcaacaattt atccattgat
    70741 agttcctccc ttgaatcatt tttattcttt tgacaagatc ttcgttactt tttcttttac
    70801 ttcttcgctg tcaatgatcg attgcaaagg tacgagcttt tcatcaggta tagaagttag
    70861 cgtatctttc aaagaatgct caatgaagaa ataatcagcc atatcgctag atacacttcc
    70921 aacatccgta tgacttactt caaactcgtc cacatctgct ccaagatctg caagtgcttg
    70981 tttgatgttc atctctacca taaaacttgt tcctaatcca ctttgacata ctgcaaaaat
    71041 tttcatatca ttcgtctcct tttcttatga tcgctaatat ttcttctttt gttgatgcgt
    71101 gtaataaatc ttgaagattt tgtttattag aaagtagctt tgttaaattt gccaaagccc
    71161 gaagatgtgc ctcattatcg atagcagcta aacagatgaa caaactaatg ggatgggctg
    71221 gattatcaag cagatccaca ggttgttgaa gtttcagcaa agacatccct acttcgttta
    71281 cgccatcttc tggacgagca tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac
    71341 catactgctc cacgcgctcg atcatagctt tgatataact ttcttctatt ttattttctg
    71401 ataatagcgg ctgtgcggca aatgtgattg cttcttgcca gttttttggt tgatccgata
    71461 attggatcat ttcttctgtt aataattcag atagcatagg acgttgatcc tccttctttt
    71521 ctaaaagttt gttcatttta cgatttaata cttgatagag cttttcttcg tctacgcctt
    71581 cttttaattc gatataaggc agtagcgccg acaacaattc ttgggcagaa ggcattgaaa
    71641 atcctggtat cagccaatct ctttgtactt gattgatcag ctgatttttt tccaagtcag
    71701 tcatgattgg atgcagaaca tagagagact ttttcttatc agtaagtgtg agaggtacag
    71761 tagaaaaaat aatatcgtaa gaagtttcgt caacctcgtg taagcggtca gctgaattag
    71821 tctctgtaaa aaagatcatc gggaataatt gctgaagttc actttttaag atcaatgaag
    71881 agctaatgcc acttggacag acgatcacgg ctcttatttt tctatttctt tcttctgcgt
    71941 ccgcttttct gatctctccg ccaaatagta tagtgaaaaa accaatctct tcttcaggga
    72001 tgctcttccc tattcgtctt tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg
    72061 aagcatattg atgcttaatt tgatcgatca tcacattagg taaataaaaa gaataggaaa
    72121 tacgaaaata ggcagggacc aagtgataaa agacattcat caataattca cgaaacgaag
    72181 caaattctac ggccatcagg aattccatgc gatggatgac ttctgaagaa cattccagca
    72241 aaaaatcaag tgcaggctcc tggacatctc cttcaacgat cgatgctaag caaagagaga
    72301 aaaatataat ctccgaattt tgatgttcgg aatagccaag gccagtcaat acttgtcgac
    72361 taatgtcagt gactgcaaga gaagccaaca gttcagcatc ttttaccagt tccatggatg
    72421 tttttccaat tcgaatggtt gtcaaactca aataataagc taattcatcc attcgatttg
    72481 gtgcgaatcg aagatctgat agtgaaatcg ttttatctag caaatctcta actttggcgt
    72541 aataatcaat ggaaagggtt gcggttaaat acgtgagccc aaatcttcca gcaagtgact
    72601 gcatcaaacg agcagtgcga ttttttgctt ctcttcttaa tattgcttct gaccctagca
    72661 gcctaaaacc agttttccta gtatacgaca gctgacaatc ttccacttct aattcatttc
    72721 ttatcttttt gatatctgac aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat
    72781 gaaaaacaga aacagacgtt gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct
    72841 cttgttcggt atacacagct tcaaatcgag taatatccaa aaatttttct gcccagtcga
    72901 ttgctcggaa tttctttata cggatacggg tatcatccac atattcggca aaaggagtta
    72961 attgtttgat cgcctcgctt gtatttactt cgatgatctc tgctgctttt tctagactga
    73021 tttctcttgg tgttttcagg agataactaa ttttgtagtt cacagcgctg ttcacctcct
    73081 acttatattc tagtatggta gcgcttttaa atcgaggggt gtttggtaca acttacagtt
    73141 ggattttttt tacgactgta ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg
    73201 tgaccaaatg tctcctgctt ttatgaattg atttcgtccg atcaatgatg atcatgttta
    73261 ttttttgagg tcagttcttc aaatttttct ttgacatctt caaccgcttt ttcgatatct
    73321 ttttcaaagt gattgggctc attaggcttt gtttcctctt ctacagaatt tgaaccagat
    73381 aaagctgttt ctttattttc tgtttcacca gagtttgtgc cagctaatga ttcttctttg
    73441 tcttctgttt caccagaatt agttcctgct aaagccactt cttcttctgt tttaggtgcc
    73501 attgaacctc ttaatcgttt gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct
    73561 agtagttcta tactttttca tcgtacaata agacagttta tgcgtcaaaa aacaaacccg
    73621 attcttacaa atatgtcata tttttccttc tgattcttga atgcttttga ttccttcttc
    73681 caaaattttc atttgtaaga ttgtttcttc atctttgatg actttttctg cgccattaac
    73741 taatgtctcg taaatccctt cgtagacacg gctgtaatca ccaacctcgg aaattacttt
    73801 ttcttcatga taactccctt gttcatctat ataggtcaat acaccataat gttcgggcaa
    73861 atcgatacca aagtcttcat gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg
    73921 atcttttgtt tgtttcacga acatcccttt ttttccgtaa acgacgaaac ttggacgttc
    73981 tttgatgcgg aaataactgg attttatcga aattttcata tttccataga aaaaatccag
    74041 atcgaagtaa tcattcattc gtcctttccc taaaagttga cgtacatcat agctgatatc
    74101 atctggttcg ccgaaataag aaagaacttg atctactgta tgacaagcat gtccatataa
    74161 atagctgttc gcagtagaaa attcatgcgt attttctggt acttccggtc tgaaataatc
    74221 ataatgcatt tctacttcta aaatatcccc taattttccg ctttcgatta ctttttggac
    74281 tgtcaagaag tcagaatcga accgtctgtt ttggtaacat tggataaata gacctttttc
    74341 ttttgctaat gcaaataact cttctgcttc ctttgacgtt tctgcaaaag gtttctctac
    74401 tagtacattc ttaccatgtt cgagtgccat ttttccatat tcataatgaa attgactagg
    74461 tgtagtgatg acaactaatt ggatctcagg atcatcccaa agatcagaca gctgatcagt
    74521 atattcgatg tcttcgaatg ttttccacac tggttcagat ggggaaaaaa tttttttgat
    74581 attgattttg ttcgtaagtt ttcttgaaaa aggcaaatga tagcgatttg tactctttcc
    74641 attgccaaga taagcgattg taagcatgag tggtgcctcc ttttattgat gttttcagta
    74701 tatcctagaa aagcgcagaa agtatttata atagctattc tggtaaaaaa gttcagaaaa
    74761 acacttgtta tcattcggtt tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa
    74821 gatagtagcg gaaccaagtg tttatcagta agatagaatt tggaggtcag atcatgctta
    74881 ttgaagaaaa actaacaaaa caagagttgt ttaccacgac agagaaacgg attgtcgatt
    74941 acatccgtag gaatatcgaa gctgcagtct acatgacgat tgaagaatta gcaaaagcta
    75001 cgtatacttc ccattcagct atcattcgtt tatgcaaaaa aatgggattc agcggattta
    75061 aagaattccg tttcgagctg gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa
    75121 cgattgatcc taattttcct ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa
    75181 tggcggattt atcgatccag tcaataaaaa aagcacaatt gcagattgaa catgaagatt
    75241 tagatcaaat cggtaaagta ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg
    75301 attctcaaat cacggcaagg aaattccaga ataaaatggt caagttgaat aagtttttga
    75361 tcatggctga agaatacagt gattcttctt ggaatgcagc caatttgact agcgaggatt
    75421 gcgccatttt tattagctac agcggtcgca tccatcatta tgaacgaata atgacctatt
    75481 tgaagcatgt agaggcccct accttgctga ttaccggaaa tcagcattca gaaatggcca
    75541 aacaggctga tatgtgtctt gttatatcgc aggaggaata tgattttgct aaagtagcga
    75601 ctttctcctc tcaaattgcc ttcgattacg tattaaatac gttattctca gtgatatatt
    75661 ctcaaaattt tgaagagaat atccgcaact tgaaaaacaa acaagaattg atgcaaaaag
    75721 gccttcttaa agaatatcgg aaaacttaag aaaagatcct catttagtaa taagaaagat
    75781 agtgtttgat aggctctctt tgatatcatc ataaaaacag gctgaagttt tctttttcaa
    75841 acctcagcct gtttgtttac ggaacgattc gaatagatat attatagaaa tgaggaatag
    75901 ctaacttctg tttcttattt tgaacgattg acgaaaaaga tatataagaa ggaggaaaat
    75961 cagtatacat gcagctaaca atccatacag gaaaaatcgt ttgttctcgg atactttctg
    76021 tacttctttt tgaacttctt ttgcatgata aggaacccgg tgccctctga caagtaagcg
    76081 atgactgttg accatataag gtgtacaagt taggagtgtc acgaaatcct gccctttttc
    76141 gattctcaga tcttttgtat cagtcggttc taccgtcttg atctgatcga cttgataagc
    76201 gagtgtccgt ccattgattt cgatatagaa agaatcacct aaagtcagtt tcggtaagtc
    76261 tgtgaacaac tttgcttgag gcagtcctcg atggctggaa ataacggcat gtgtattttc
    76321 tccccccgta ggataagacg ttccttccaa taatgaggca cctttttcta gcagcacagt
    76381 attcgtttca tcaaaaattg gcaaatggac attgatctca gggatcgtca aaataccgat
    76441 cgtatgtttc tcaaaatagg ttctatcctt tttcgcaggt tcttttttct tagtaaaggg
    76501 atctgcacct ggatttccac cttcttttgc taattgctgg tttttctttg tcatgttttc
    76561 ttggatttta gccatgactt cttcattttc tttgaccgct tgttgctgat aatgagagat
    76621 gatctgctga tccagataat tattcagcgc gtcgctaaca aatggataag ctagtatccc
    76681 tattcctgag agaagcaaga aaagcatcag cagatctaga agtttccttt tctttggttt
    76741 catttgtgtt ctccttgtga tgactgtttg ataataaaag aaaaaggagc atttgcgtaa
    76801 tccgctgctc ctttttccaa ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag
    76861 caaagtacag tccagcaatc agtagaagga ctactcctgc accgatatac acatagattc
    76921 ccttaccgcc tgttgaagga agtgtacctt tgtgtttatt tggtattttt tcaggagaaa
    76981 tcaactgtcc tgctgttaca taagattgtt catcgatagt aaatgctaca cggtttgtta
    77041 atggaacata tttttctggc gctttcgttt cttccagata gtacgtgcca tattttagac
    77101 ctgtcacatc gattaaaccg ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg
    77161 atacccagct gacggctttt gtggatgggt cgatcgataa atatttcgct gtgtcactat
    77221 cttgatcacg aacgacgaat tctgctccag caagtgtttg gtctgatgta acgtcaccat
    77281 ctactttaac aaatcgtttg cccccagtaa cgacatcgac tgacggtggt gtttgatcat
    77341 ttgtatgccc gttatcgaca tttgcttggt tagaaaatcc tttggttgga tctgcttttt
    77401 cgttcaaatg catatagtaa acgaatttca atgtaccgcc aggagttaat gaaggaatat
    77461 aattcggatc aactgaaacc gtgaatccgt ctgtttgctc agtgacagaa taatttactg
    77521 ggtcgatttc tttatttcca tcatataagg cataagcata cgttcctgaa gaatcattat
    77581 caaatgttaa agcagcgtca tgagtatcga taagtttgaa tgttgtgtac ttgttttgcg
    77641 ttccttcttt atcagcgata cctaatggga tattgacaga aatctcatat tgaatttttt
    77701 caccgattgc gacatctttt ccattcaatt gaggtgttgt tttatcaact ttagacgtat
    77761 catttttgat ggtcttttct actggtgttt ggctatttgc caggatctca aaaggcgtga
    77821 ttgtttgctt ttcaatcatt tccgcattat caggagcttt tacttcttct aaattatatt
    77881 ttccaacttc taaatgatta acgatcaact ggcctttttc aatagatgcc tcggcaaagt
    77941 cattgttgcc gatgtcataa gaatgaccag taatgaaatg tttggctttg gtttgatcag
    78001 ttgtccaagt gtacaatcca tctgtgacac tttggatgta ttttttgacg cttggtgttc
    78061 cttcttcttt agaaataata aattctgctc catttagtgc ttcgttttcg gcagtaccga
    78121 tttttgtaac tttcaacgtt ccatcattac cgactgtatt tttagggtag agatggatag
    78181 tatctagttc ttctgtcccg tatttataag agccatctgc ttgtttgatc atctcatata
    78241 cagggaaagc taaaaccatg tttgcggcag ctgacactcc gtcttttggt tcttctttga
    78301 tcgtgtagac tgcatctttc ccattttgtt ttttaggtaa agataaagtg acatttccat
    78361 cagcatctgt cgttcctgaa gcaactggtg taccaggagt caaagactgg actgcttgtt
    78421 ttgctgcatc cacggacgct cctttatctc gttgcgcata aaattcttga gtgacgttat
    78481 aaactgaaaa tgaaatatcg gctaatcctt ggtattgatc gaattcgctc atttctttcc
    78541 cgctgttttg gattaaagga tcgggtaaat cagtcatttt ctttttatga aggatgactt
    78601 gagctgctgt ctcctctgca aacacttttt ttgcgccgaa gctgtttgtg agtaatggta
    78661 aaataaggaa aaggactcct aacataacgt ttattttttt atgatttttc attttttcac
    78721 tcctgttctt tttttgataa acaaccagat tgcaaagctt gcgaatacca taccaacaac
    78781 gcctaaaagt gtatttttcg tttcgtttgt ttttggaaga aatggacggc tattttcttt
    78841 tttattgact actttcaata tactgtccgc ctctttatcc tcagaaagaa aagttgaaat
    78901 ggtaaacgga atttctgttt cacttaaaat ataaccagaa ggtgcttcga tctcttttaa
    78961 tcgataactt cctgttttca acccggaaat tgaaaaagcg ccatttttat cggaaatcag
    79021 gtgaagcgca tctgattcgt tctttgtcca cttgtatccg ttggctgttt gctggaggta
    79081 atttcctgct ttgtttttaa taaggaatac tgcgccagct aatcgtttat ctggtttatt
    79141 tgtctcgatt ttgacaaatt gcttactccc tgtatataca gagactttct ttgtactgac
    79201 accaaaacca aaatccagtg ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact
    79261 gcttagctgc atctgataag aaatggtcag tttttttcca gcatattttt ccaacgaagg
    79321 gatcgaaaat aaaacatcaa atccgtgagg tttcttgtgt atgacaaagc cttctgtcag
    79381 cttttctcca ttcgatgaaa tcgttaaact attaggtaaa aacgttaatg cttcatccgc
    79441 actatctgac aattcgaact tttgatagtc aaggatattt acaggaattg tcgtatgcaa
    79501 ggaataagtg attttttcac caatcgtaaa atcatttcta ggctcttcta ataccttctc
    79561 aaaaggtgga tcagggtagt cgttttcttc atttttagga tacaaatgga tagttgaaag
    79621 tttttgattg ttttgtccat gtacaggaag aacaactacc atattctctg ccttttcttt
    79681 gacgacttct ggtactttgg attcaatgaa aagatacgct ttatctcttt tttcttgatc
    79741 tttagcggcc agagaaaaag aagcgatacc atcttcgttg ttaagagttg tagttgttgc
    79801 ttctgcggta aacataccgg aagacgcacc gttttttgcg atctctgctt gtgcttcttc
    79861 taccgttttg cccttttccc gtagatggta aaaagaatct gtgacatcat aaacttggaa
    79921 tgtgacacca tttaatcctc gatacgtttg taataaagct ttttcttgtc cgtcatttgg
    79981 atgatttttc ggcagttgcc cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat
    80041 ttctgtttct gtttctgttg ctacctgagt aaaagctggt ttaaatagta acaagaagag
    80101 acacatacta agccaaccaa gttttttcat atttagctgc cccctctttc ttttttcaaa
    80161 aaaagatacc aaatagaaaa cgcacaacca atcatcccta ctagatagat tcctaaacgg
    80221 ccaattcctc ccgtttcagg taatggtact tttgcctgat tcgtgatgtc taaagaaatc
    80281 tggttgtttt tggctcctgg tgacagaaca gattcatgat cttgtccatc cacttgaatt
    80341 gacccatctt cgtgtataac tatagtaact ggctctttta gaccttggta tccttctggt
    80401 gtaaaagttt cggtcagcgt ataagttcca ggttttaaat tttcgaatag aaaggtatct
    80461 gtttcttgtc catcttttgg cgattctaag tccatttctg gtccctgcag tctgaatttt
    80521 gctcctttta atgtctgtcc gttgtcttct tttttgtgta ccgttagatc aaacgctttt
    80581 agtcgatttt gatgagtgag cgtccataca ttatttgtca tctcggtatt ttttcccgtg
    80641 taaatgattt ttccatattt atcgatttgg aattcataat ttcccggcga agtatcatat
    80701 ccggcaggac cagctgtttc aacgactcga tatttaccag gtgtgagtga atcaaaactg
    80761 gcaagacctt tttcattcgt tgtttggctg tcaattggct gataagtacc atttgcttct
    80821 tttttctgta gggaaaatgc tgctccttta agatttatct ctttgtccgt cccttgcatc
    80881 gcatacttac gtactgctac aggaacttca acaaaaggat tttcaatagt caactggatc
    80941 gtatcatcgg aagtagtgac tgtttttcca tcaatggtta ccgtaccatc agaagcgatc
    81001 ttgatttccc aagtagtctt tttgcttaat ccatgccctt ctggagcttt tgtttctgtc
    81061 agcgtatagg tcatttcttt ttgcaatttg acattttctg gaagagaata ggttccgtcg
    81121 ccatgatctg ttagtaaagt atcaatagaa tctcctgtta atttgaaaac agcgccaata
    81181 agatcctttt cacctgtaga ggaatttttc gttattttca agtttaacgg tgtgaattgt
    81241 ttagtatttt tccatgtcat tgcatctatt tgttgagaat cgtatcctgg tacaggtaat
    81301 tctttgattg tttggtaact gaatgcttga ccttgattat tgtattgagg tagtgataat
    81361 atctcttgat aactttctcc gctatttgca gataatttgt caatgtctgc acgttcccac
    81421 gtatttgttg tatctttagc tggtttaatg attcgaatat atccgttttt ccaagctgca
    81481 gcatttgtcg tatgttcccg ttgaatctca aaagtaactt gatctggacg atcagctaga
    81541 ttgttgtcaa attcttccca taactttttg atgtgaagac tgactccggg agctttagca
    81601 gatggtatac cgaattcagc taattcattg gtatcaatgt ttggctggaa agttgtcctg
    81661 ccgttcattt gataccagaa atttggatgg aagtcctcat tttctgtttg gattctcact
    81721 tggtaatgga tttggatttc ttggtctttt cctaaataga tctgattgct cttgatggta
    81781 tttccttcta tggaaataga tggagtgacc gttgtaggac ttgtccccac actcttgact
    81841 gaaagtgtac caggctgata aatgaatggt tctgcgattg gatcatttat ttgtccattg
    81901 cttacagttg ctgagatctg tacagctttt ttggctaggt attcagagat atctgttgca
    81961 tgatcagctg attcatagta aagatcgcct ttttcatctg atgaaaccat ttgtcgcata
    82021 cgagactcta cttctgcttt tgagagacca gctgccggat cgctttgaag ttggatgcca
    82081 agaccatgta tttcgattcc tcgttctttg agtgccatcg cttctccgat ggttgcgata
    82141 aacgtactgt cgattcttct ggatagattg ttttggtcag gtgcatcata gattcttgag
    82201 attagagaag tatttcccgg ccgatcttgc gtattagaaa actgagttcc gtaataattg
    82261 ctgcttgatt gtgcgtgtac ccgctgtact ttataggaaa atgttggtac accatccgtc
    82321 agcaaaacga tcactttttt atgtccattt ggaacggata gcatgcttcc tgcatctctt
    82381 agtgcttttt gtgtaaaagt accaccattt gtccgtgaag gtgtaatgga ttttacttga
    82441 tttttcactg aatcaaatga acccatctgt actgcaccgt tactgtagct atatccttcg
    82501 cttgagtagc cgacatatcc catattgatt ttgtctgtga taccgctatc tgctaaagta
    82561 tcgacaaaac gatcgacacc aatctttact tcaccgatcc gattattgtc gttcatactt
    82621 cctgaccagt ctacgaccaa tacgagatca agaggcgtga tatctttttg tacatttcca
    82681 cgagcattca aataaacatc aaacaatccg ggtgtacttg tttcctttgc atactttcgt
    82741 atcgcatagt ctgcttgatt accggttcct ccatattcga tatacgaatg ggtccgatca
    82801 ttaggatctc cattccaaga atttatacca tcccattgat ttgttccgtt tttattgcct
    82861 tgatgatcaa gaacatttgt atttcctgta ggttgccaac tggctttagg ataagtgccc
    82921 tgatcatctg ttgtatattc tgtaggaatc gtttgattag atggcacact cacagctggc
    82981 aaggataatg taggcaatgt aaatgggctg acagaatttt cgttttcttt tgatgattct
    83041 tcttctattt cgtctggctt tggtactgac acatctgtat ctttcttatt ttctgtctca
    83101 tcaataatgt catattcttt attatcgacg atcagcttgt ttgcctggct gtggtaaagt
    83161 gctggatcga ttggaaaact cagatcgata gtttgtttag tgtttgatga gatttccaac
    83221 gtaattttcc cgctatttac ctgataagca tagccatctc cttcttttct ttccacatca
    83281 cttaagtaat tttcgactag accaatttct ttttctatct tttcagcact ggtgttattc
    83341 gcatttagct tgatgttcag tgcttttttt ccagactgat ccgaaatgac ttcagctgaa
    83401 attgtttcta aaactgttgg atcatctgta gtgtctgcta ttgcagataa tggcacaaag
    83461 tttgataaac tcaatattat cagcatgaaa ataactttca gtttcttccc tgtggtcgtc
    83521 atttttcccc tcctttttct ttttttctgt tttgacgtga atagtgaaaa ttattaaaat
    83581 aaacaggcgt tacataattt tatttatttt aatatgataa ttattatacg aagggcgcta
    83641 aagggaatca caccaatttt cataccaatt ggtttcattt atgaagttga ttccttcgat
    83701 taatgagcgt ttcattgaaa gaaaagggtt gagggagaaa aacatatgat caggttgttg
    83761 gaaggaaact atagaaagat ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg
    83821 atgactaaaa aagaacttgc caaacgaatt ggtagttcag aatctacatt tgtaaggtat
    83881 atcgaagaga tcaaaatccg ctggggaacg gatgtaacga ttcaatcttc acaaaaattg
    83941 gggtatcgtc ttgaacattt gaatgtacca gcttatttaa atgttctgat ggaaatgtcg
    84001 caaagttcta caaacagtcg tttattaaat gagattattg tcaatccggg taaaacgatt
    84061 gagtattatt gtgaaaaaat ttccatcagc cggtcttctt ttacacgtaa gttgaaacaa
    84121 tgcaatcaaa ttttagaaag ctatttatta aaagtgatcg ttgaccaagg ttttcagtta
    84181 actagcctta aaagtgagct ccagttgcgt atctttgtta cctttttctt tttaagttac
    84241 tacggaagac gcacgttgcc atttccaatc gaaaaaaaga agatcaaaga aattatggtc
    84301 aagaataatt gtcagatgaa tttgtttcag gaagaaagcc catatgagca atctttcttt
    84361 attatgtatt ttgttgtgca tctcatgaga gaatcccaag gaactccatt tgaatggaaa
    84421 gctggagact cttatgtaca gttgataaat atcgataaaa aagacttctt aatcttgaaa
    84481 aatctcttag gaaaattgaa gtacagcagc tatataaaag tagtgaacta ttttgtcaat
    84541 acgatttttt cagaattttc ggagaaagaa aaaaatgaaa tcagtgagca gatacgaaaa
    84601 aatatgtcct actgttcgtt ttcatccgct gattgcaaag aaaaaaacga agaatatgtt
    84661 gttcaattat taacgcaaat ttattttttc tcccgtattt tcccatacga tacgactcat
    84721 ttgacgatcc gtgcaactta ctttgcacag cagatgcaac accgccagat acgtctatat
    84781 gctggatttc gtgcagaact tcaattttat tccactctac tgaatcagaa tctgatttat
    84841 tatttatcta gctatatctt ttggatgctt atcggtaatc ctgaaattca ccattatact
    84901 tctgataaaa aaatactgat tatcagcgac ttaagtcttc gacatagtca atatattgaa
    84961 gaatatatca gtgatattct tgctgtgcat aaaattcact ctgagacaac tgctattact
    85021 gaagatcagc tgtcgaaata caatcttctc gagtatgatc tgatcgttac gaatcaaccc
    85081 attttgaatg cccatgttcc tcatatattg attgatgata gtgtgtcatt cgcaaatgaa
    85141 gaagaactca tccgcttatt cgagttatga ataatcaaaa aacagctatg tataaaccac
    85201 cctgataaaa atttcaggac aaatacacat agctgtttct ttttattgta ttccttcagc
    85261 aatccaacga gatttatagc gaaagtcttt taacaactct tcttttgtcc aattatttgc
    85321 aatgagatcc gtcaaagtgt tcattacgag ggtcatggaa aagtatagga aactaactgc
    85381 ttcttccgac gattgaatgg agaaatgatt gattcttaat aattccagcc atttttcgtt
    85441 cattggagaa tcagccgata gttctctacg tttggttgtc tgctgatcat ttcgctgggt
    85501 taacaagtat aacctttgcc aatagatact ttcgtgatct aagtcgcagc accactctaa
    85561 atatttttcg atccccaaaa agaaatgttg tttgttttcg ctaatgaatt ttaagatatc
    85621 ttgatggact atgtgagaac tgcttttgat cgtatacaaa taagcatctt ccaaatcttg
    85681 aaaatattta taaaaagcac cgcgcgacat ccccatcttg tcaacgattt ctgagacttt
    85741 gacttggctg atgtgctgtg agcaaaatat ctccagtaat aggtcatcga ttctctgttt
    85801 ctttgcgttc gataaattga aaaaagtttc ttttggcatc cacatctctc ctttatctct
    85861 gattatacgt ggatagccct tcattgtcat gaaggattca ttccttcttt ttctcttctt
    85921 ctgtcaagta cccatcttcc attcgataaa cgcgatcact ccattgaatc atacggacat
    85981 catgagtaac cataatagtc gctttttgtt tctcatgagc ttctttaact agtaatttga
    86041 cgacttcata tgcatgatct gtatccaaac tagctgttgg ttcgtctgct aagatcaagc
    86101 ttggctcatt atataaagcg cgagcaattg ccactctctg tctttctcca ccagaaaggt
    86161 ctttaggata actattttta agtgactgga tatctaaaga ttgcagcaag gaatcgattt
    86221 ttgttgaatc ttcttttttt gaagtaactt ggtcaactag ttcaaattgt tcctttaccg
    86281 ttaaaaaagg aatcaaatta gagctttgga gaataaatcc tatttcttta aagcgtaaat
    86341 ctgctcgttt tttttctgga agctcagtta gtgagtgacc gttgatcact atttctccgg
    86401 aagtcggtgt ttgcaatcct cctgaaatgg taaggaaagt acttttacct gaaccagaag
    86461 gaccaatgat gctgacgaat tctccttcct ttacataaaa atcaattgct ttcaaagctg
    86521 agaccattgt atgaccagaa ccaaatgttt tggtaacttt tttcatcgtt aatatttttt
    86581 tcatttttat taacctccta ttgctgtaat tgggtctact ttggttatcg tacgtatcga
    86641 aaacaatccg cctagcattg cgacaatgat caaaatccca ctatatagca accattgtga
    86701 ccaaaaaaca gcaaaaggca tcgcgcttgg taaaatcaga ctagtcaaat aagcaaacaa
    86761 aagagcaagc agaacgccta ccaccccaac aataaaggac tgtgctacta aagatttagc
    86821 gatgaagaaa tttttgatcc cttgtgcttt cattactcca aaaatagcag tcttctgaag
    86881 tgtcatcacg tacatgaaaa taccgaccac ggcagcaacc actaagaaca aaaagtatat
    86941 catcgcattt aaggtcatat tttgggcaga atagccagga atactttcaa tgaatgtccc
    87001 aatagttaat aactgtagac ccttcgatgc tttttctttc gaaattttag ctgaatcctt
    87061 tattacgatc ccattgatcg gctgttcttc ttcagaagca aacggctgtt gtccatactt
    87121 caaagcagtc cacgtatcta gggacgcata gatgacggga gaaactgtgt aataagtttc
    87181 aggaaagata ccgacaatcg tcaaaggatc gtcgtaactg ccaattttga tcgtatctcc
    87241 aattttatag cctgaatcag ccagattttg agagatgatg atttcattct ttgttttaaa
    87301 ttcatgccct ttcgtgagtt ttggtaataa aaatgcttct ttcgttgtgc cgaaaactgt
    87361 aacattttct ttgttttttc ctttgattgc tccgctgtac aatccgattg gtgctttctc
    87421 tcctccttca atgtatttca gatctcctct tgttaattgt gaagctgcaa atacttgatt
    87481 tgcatcctcc gacaaaacaa tctcttgtgc gtcccaatca tcgattgctt ttttaaactc
    87541 ttctgaaagt ccattcgcta gtcctgacaa catgaatacg acatacgcaa tcaagaacat
    87601 aataccgacg atcaagccat atcgtaattt agaatagcga atttctttga tagctagaaa
    87661 catttgtttt tcctccctat gatagattga tagtgacaaa atgtcacttg ttgaatagtg
    87721 taactctaaa gtgacaattt gtcacttgtg ttgttttttt cttatcaata aattgtctaa
    87781 gacatctttc gataaaacct taacatgagt cataaaaaat ttatttaagc cttatttatg
    87841 ctttccatga taaactaaag tgaccaaatc aatgaggtgg gaaaatgatt aaactattag
    87901 tagtagaaga cgataaagta ttatccaata atataaaaga aatactcgct gcaatcggcg
    87961 agataacaca agtttatgat ggtagtgaag gactgttcga gttggaaagt ggagtttatg
    88021 atcttgcaat cttggatttg atgatgccgg aaatgaatgg atatgaagtg ttagcaaaaa
    88081 tacggaaaga aaaaatacag actccagtat tgattttgac tgcaaaagat agtttggaag
    88141 ataagattga aggatttgaa cgaggtgcag atgattatct aacaaaacct ttctatcgag
    88201 aagaactgat catgcgcgtg aaagcattat tgaaacgctc gctaggtctc tttgatgaaa
    88261 atgttctgaa gtataaggat atcagttgtg atttaaaaag caatgaagtc ttgtataaag
    88321 aacaagtttt gcccatacaa ggaaaagagt ttgaattgct cgtttatttt ttacaaaata
    88381 agggaatcat tttgacaaaa gagcagatat ttgaccggat ctggggattt gattctgata
    88441 cgacgattac agttattgaa gtttatatga gcaacttacg aaaacatctg cgaagtactg
    88501 gattggataa agaaatcaaa accttacgta atgtcggtta tatactgcaa agggtgtgat
    88561 gcaatgaatg gagatattac acgaaagcaa cgtagtcgct tttttgcgac aaatgtagca
    88621 gcatttgctt ttatcttttt tcttttggga ttcattactt tacagatatt aaaccaatct
    88681 gcatacagag aaacagatct gtcattagag aaaataaatt ttgattctcg aacagtacaa
    88741 ttagagatac aaagatatca gcaaggcgat ccctttttaa acccgactca aacggaacaa
    88801 aacagaacaa acatggaaca gccattaatg gaaccatcaa atgaccgttt taacactcaa
    88861 gtgatcttgt ggtctaaaaa tggtgagata ttgaataaag cagctattgg tgggcgtttc
    88921 aaccaaatca aagaattaaa aatggatacg aaaaatctga ataccatcca aaatattgaa
    88981 ttaaatgaag acagtggctc atctgccctc tctttccgtt cgattacgaa aaaagcggag
    89041 acgaatcaag atggcgttgc ctacatccaa attttagaaa atacaaatca aatcaagaat
    89101 tcattagcga cttttcgcac gattatgatt ttgtgtatga ttgttttttg gattctctct
    89161 attggtatca gttattactt gtctagtcta agcatgcgcc ctattattct ttcttggaga
    89221 agacaaaaag aatttgttga gaatgcttct catgaattgc gcacaccgtt aacgattatt
    89281 caaaatagtt tggaacatct ttttaccaag cctaatcata ctattattga agaatccgaa
    89341 agcatcgctc aagcattgtc agagacgagg cgcctcactg gattgacttc ggatttgctg
    89401 acaatcgctc ggaatgattc tgatcagcag ctgctttcaa agcaaatgat caatacacaa
    89461 gaatatatcg aacaacttgt taaaccattt caagagatgg ccatcataga tggaaaagag
    89521 tttattctcc ataacgatgc aacattagaa gtaccaattg atgaaaaaaa aatccatcaa
    89581 gttttggtta ttttgctgga taatgcatta aaatatacga atccagaaga taagatcatt
    89641 ttggattcat ctgttaacca taaagaatgg ctgattcacg taaagaatac tggcccttct
    89701 atcagtgaag aagatcaagc aaggattttt gatcgatttt atcgggaaga tcaatctcgg
    89761 gcgaaagaga ctggcggata cgggcttggc ttggcaattg caaaacaggt aatcgaacag
    89821 catcatggac agatttctgt atccaattat cttccacaag gagtcgattt taaagtccaa
    89881 ttgccgttga agcctaaaaa ataatgctta tccctaaaaa agggctgtga caaaaatctt
    89941 gtcacagccc ttttttgttg cgaataaacg gtgttccaga agtagcttct tcggaaataa
    90001 gccgaaattt ctttaagctg accacttctg tcacaacctc tttagcttac gcttacgatt
    90061 ttttattgcg gtcttcaatg tgtacatcac cgcttgtgtc aatatccaat tcttctcggc
    90121 taacatcttc tgtcactttt tcaacatctt catgttcttc tttatgaatc ccaacttctt
    90181 cacgaataac tgtatgtttg cttacatcta cttgctcttc tttgattggg atagtaatcg
    90241 tgtcatcttc caatttttcg tctgttccct gtgaagattg atctgttact ggtttgcgtt
    90301 cgatgacgat ttcttcacgt ttgaccggta cttctaccgt ttcagtatcg ttgaccacat
    90361 gtttgtggat gtcgacttct ccagttgtca catcatgtgt atttacatct aatttttctt
    90421 cttttagttg aattgtatca tcatctagat ttggtttgcg atcgatgtct tcagtcttgc
    90481 ttgtacccat tgtatcagtc tcgccaggta cgtccatcgg atcagttcct ggtgtcatat
    90541 tcaatggatc cgttgtattt tgaaagcctg tcgtgccacc tacgtccatt ggatctgttc
    90601 cagtgccagt ttctaatcca gtccccattg tgcttgctgg gctaacagta tcttgtgtat
    90661 ccattgtatc ttctgttgtt tctggctgac gatagccttt tactgtgatg acaaattttc
    90721 catcagaaat atctcctcta tattgatata aaggatcatt ttctggtgta gccgtctcag
    90781 aatcataggt atcaaaagaa aaagtatctt ttattttttc ccataaagaa cggtcttctt
    90841 caccatccat ccgattttca tctgtttcaa catctatacc agacaatccg tcaaatccta
    90901 gtctagatgc tgcttcatca gtagtataaa taacgatatc atctcgttca tacccttcgt
    90961 tacgcaaccg ttcaattact gataatgctt cttccctcgt actatagctt ccgatgaccg
    91021 ttaaattttt ctcttccatg taaattcctc ctagcaaata gatttatgat tggtatattg
    91081 ttacttataa atttattcta taggagacga ttgttttcta caaatattta gattggaatt
    91141 tgattaaaac aatttaattg aaatttgaaa acatttatgt taatgaaagt catattctaa
    91201 taaaatgtca tttgtttcta tatgaatttt tatgaaaaat ttcatataat ttccactcgt
    91261 tgtgatggtt taatttatcc aatccatcaa taagcaaaca acttatataa aaaaggatta
    91321 attctcaata taattgctcc taccatagaa taaatcttca tgtaaagtaa tgaagtacca
    91381 actatttcta atacttcttt aagaattatc ccaacaatat cgttagacaa accattattg
    91441 aataaatgga gagccaatcg attctgaaaa aatgttttct aatttttcgg aaataaaaga
    91501 aagagcctcc tgccattaga acgaaccaaa tccatttcat tgctcatgaa gtaaccacat
    91561 agctaaaaag aggataaatc aattaaaaga tcaaaagaat gactgcacta ataaaataac
    91621 taaaaatgta tcttcttact tcatatcttt tagctagtac ttagttaaaa atttgcttcc
    91681 taagatcaag acaaactgtc tatcttcatt tgatgaaatg cggtaaaata tagaaaatga
    91741 acactattgg agggaatttg taatggacag caaaactaga aaacaactgc aagaaaagtt
    91801 aaagcaacgt acacacttgc tcccttccgt ctttcaacag tttttagaag aaaatcgttc
    91861 ttccctttca ttaggcagtc gctatgaata cgcaaaagat tttcatctgt ttactgatta
    91921 tttgagaaaa gtattttctg aagaagtgga tgatcagctg attatccatt tagaaaaaca
    91981 agattatcag aatttcttag ctaaaatcta tcgacatact cgttcgttcc aaactacagc
    92041 gaaccaagaa acggagcaat tgtttgaaaa tagctattac gggatttcaa ggaagcaata
    92101 ttcattaaat cattttttac gatttttgta tcaaaaagga ctgattgaag aagagatttc
    92161 tcttttgggt acaagtttac cggaaacaac caaagcagct ccgcgatata tcgatgcaga
    92221 acttttcaaa gattttgagc atttgtttat cccgattgaa ggctttcaaa caagcagaga
    92281 agctagcttt gaagaaaaga atagaccgag gaaccttgca attactgcca ttcttctgta
    92341 ttgcggatta aagatccatg aagtagtaga acttaaacgt aaagatgtat ctttgaccaa
    92401 gcagattctt aatctgaata gaaaagaaaa cagactgaat aaagtaccaa taccaaaaga
    92461 agcgatgcca tttctggaga actattttaa gttaacagca caaaatacgg acgaaaattc
    92521 ttttgttttt cgttcctcac atgatcagca aatttctcct cggactattc gccaaatttt
    92581 gagcaaaatt acagtatata aaaacgtatc gccagaacta tgcagaaaaa catatcgtta
    92641 ttatgcagaa ctatatttag atgatgctga cgcggtaaat tatttatgtg gtaatcgata
    92701 cctctcatcc cattcttttc aagatatctg ggaaaagatg gttgattttt cttatcacga
    92761 attagcggca ttcgttcggg tttcttccat ataaaacaaa tgtatgatct ttttttcaca
    92821 ataaactatg ttattatata aaggattatg ttacgattat cttgaatttg tatattactt
    92881 aacaaaagat aatggagtgt gaatgatgga gaccataacg tattcccctt tgaacttatt
    92941 tacgaatttt caagaagctg cagctaactt ttccgagacc ccgattatct ttgatgagcc
    93001 actttcagct ttcccagaat taggacttga aacaacttac aaaaaatgct gcgaaagtgt
    93061 gttgaaacgg gcttatcaat tggctcatct tggagtgaaa tccggagaca aagttattat
    93121 ttataagagt tccgcttttg acacatacct tctagctgtt tctgtgtctt accttggtgc
    93181 agtgcctgtc atgacttctt atcatctacc aacaacaaca atggaagtat ttatcgatcg
    93241 tttagaagac cctttcattt tatttgatga tgagacaaaa aagcgagtga gagaaatttc
    93301 aaatggaaca aaatcaaaac agattc
//
LOCUS       DBBGRF010000003        80050 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000003 DBBGRF010000000
VERSION     DBBGRF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 80050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.003"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            125..1168
                     /locus_tag="ACIZD4_000210"
     CDS             125..1168
                     /locus_tag="ACIZD4_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HGC5989178.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1230..1694)
                     /locus_tag="ACIZD4_000211"
     CDS             complement(1230..1694)
                     /locus_tag="ACIZD4_000211"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGC5989179.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            1940..2887
                     /locus_tag="ACIZD4_000212"
     CDS             1940..2887
                     /locus_tag="ACIZD4_000212"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC5989180.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(3098..5170)
                     /locus_tag="ACIZD4_000213"
     CDS             complement(3098..5170)
                     /locus_tag="ACIZD4_000213"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGC5989181.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(5103..5480)
                     /locus_tag="ACIZD4_000214"
     CDS             complement(5103..5480)
                     /locus_tag="ACIZD4_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGC5989182.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(5609..6169)
                     /locus_tag="ACIZD4_000215"
     CDS             complement(5609..6169)
                     /locus_tag="ACIZD4_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5989183.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            6319..7611
                     /locus_tag="ACIZD4_000216"
     CDS             6319..7611
                     /locus_tag="ACIZD4_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGC5989184.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(7671..8789)
                     /locus_tag="ACIZD4_000217"
     CDS             complement(7671..8789)
                     /locus_tag="ACIZD4_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HGC5989185.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="ACIZD4_000218"
     CDS             complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="ACIZD4_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HGC5989186.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="ACIZD4_000219"
     CDS             complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="ACIZD4_000219"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGC5989187.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            11995..12594
                     /locus_tag="ACIZD4_000220"
     CDS             11995..12594
                     /locus_tag="ACIZD4_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC5989188.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="ACIZD4_000221"
     CDS             complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="ACIZD4_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HGC5989189.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(14289..14633)
                     /locus_tag="ACIZD4_000222"
     CDS             complement(14289..14633)
                     /locus_tag="ACIZD4_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGC5989190.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(14770..15915)
                     /locus_tag="ACIZD4_000223"
     CDS             complement(14770..15915)
                     /locus_tag="ACIZD4_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGC5989191.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(16095..17069)
                     /locus_tag="ACIZD4_000224"
     CDS             complement(16095..17069)
                     /locus_tag="ACIZD4_000224"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGC5989192.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(17149..18024)
                     /locus_tag="ACIZD4_000225"
     CDS             complement(17149..18024)
                     /locus_tag="ACIZD4_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HGC5989193.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            18154..20061
                     /locus_tag="ACIZD4_000226"
     CDS             18154..20061
                     /locus_tag="ACIZD4_000226"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HGC5989194.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(20602..23880)
                     /locus_tag="ACIZD4_000227"
     CDS             complement(20602..23880)
                     /locus_tag="ACIZD4_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HGC5989195.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(24151..24696)
                     /locus_tag="ACIZD4_000228"
     CDS             complement(24151..24696)
                     /locus_tag="ACIZD4_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGC5989196.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(24708..25400)
                     /locus_tag="ACIZD4_000229"
     CDS             complement(24708..25400)
                     /locus_tag="ACIZD4_000229"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGC5989197.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(25419..25703)
                     /gene="macP"
                     /locus_tag="ACIZD4_000230"
     CDS             complement(25419..25703)
                     /gene="macP"
                     /locus_tag="ACIZD4_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGC5989198.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(25716..26279)
                     /locus_tag="ACIZD4_000231"
     CDS             complement(25716..26279)
                     /locus_tag="ACIZD4_000231"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGC5989199.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            26507..27169
                     /locus_tag="ACIZD4_000232"
     CDS             26507..27169
                     /locus_tag="ACIZD4_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HGC5989200.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            27293..28489
                     /locus_tag="ACIZD4_000233"
     CDS             27293..28489
                     /locus_tag="ACIZD4_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HGC5989201.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(28590..29966)
                     /locus_tag="ACIZD4_000234"
     CDS             complement(28590..29966)
                     /locus_tag="ACIZD4_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC5989202.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(30003..30869)
                     /locus_tag="ACIZD4_000235"
     CDS             complement(30003..30869)
                     /locus_tag="ACIZD4_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HGC5989203.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(30958..31983)
                     /locus_tag="ACIZD4_000236"
     CDS             complement(30958..31983)
                     /locus_tag="ACIZD4_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC5989204.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(32001..32675)
                     /locus_tag="ACIZD4_000237"
     CDS             complement(32001..32675)
                     /locus_tag="ACIZD4_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC5989205.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(32859..33752)
                     /locus_tag="ACIZD4_000238"
     CDS             complement(32859..33752)
                     /locus_tag="ACIZD4_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC5989206.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(33826..35523)
                     /locus_tag="ACIZD4_000239"
     CDS             complement(33826..35523)
                     /locus_tag="ACIZD4_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC5989207.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(35516..36829)
                     /locus_tag="ACIZD4_000240"
     CDS             complement(35516..36829)
                     /locus_tag="ACIZD4_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HGC5989208.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(36829..40770)
                     /locus_tag="ACIZD4_000241"
     CDS             complement(36829..40770)
                     /locus_tag="ACIZD4_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC5989209.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(40879..41337)
                     /locus_tag="ACIZD4_000242"
     CDS             complement(40879..41337)
                     /locus_tag="ACIZD4_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC5989210.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(41635..42153)
                     /locus_tag="ACIZD4_000243"
     CDS             complement(41635..42153)
                     /locus_tag="ACIZD4_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGC5989211.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(42155..42772)
                     /locus_tag="ACIZD4_000244"
     CDS             complement(42155..42772)
                     /locus_tag="ACIZD4_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGC5989212.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(42769..43623)
                     /locus_tag="ACIZD4_000245"
     CDS             complement(42769..43623)
                     /locus_tag="ACIZD4_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5989213.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(43620..44531)
                     /locus_tag="ACIZD4_000246"
     CDS             complement(43620..44531)
                     /locus_tag="ACIZD4_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5989214.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(44572..45906)
                     /locus_tag="ACIZD4_000247"
     CDS             complement(44572..45906)
                     /locus_tag="ACIZD4_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5989215.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            46114..46944
                     /locus_tag="ACIZD4_000248"
     CDS             46114..46944
                     /locus_tag="ACIZD4_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HGC5989216.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(47188..47437)
                     /locus_tag="ACIZD4_000249"
                     /pseudo
     CDS             complement(47188..47437)
                     /locus_tag="ACIZD4_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(47628..47822)
                     /locus_tag="ACIZD4_000250"
     CDS             complement(47628..47822)
                     /locus_tag="ACIZD4_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989217.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(48327..48512)
                     /locus_tag="ACIZD4_000251"
     CDS             complement(48327..48512)
                     /locus_tag="ACIZD4_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989218.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(49362..49703)
                     /locus_tag="ACIZD4_000252"
     CDS             complement(49362..49703)
                     /locus_tag="ACIZD4_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC5989219.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(49703..49933)
                     /locus_tag="ACIZD4_000253"
     CDS             complement(49703..49933)
                     /locus_tag="ACIZD4_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC5989220.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            50220..50558
                     /locus_tag="ACIZD4_000254"
     CDS             50220..50558
                     /locus_tag="ACIZD4_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989221.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(50763..51325)
                     /locus_tag="ACIZD4_000255"
                     /pseudo
     CDS             complement(50763..51325)
                     /locus_tag="ACIZD4_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(52057..52638)
                     /locus_tag="ACIZD4_000256"
     CDS             complement(52057..52638)
                     /locus_tag="ACIZD4_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5989222.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(52821..53447)
                     /locus_tag="ACIZD4_000257"
     CDS             complement(52821..53447)
                     /locus_tag="ACIZD4_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HGC5989223.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(53469..54800)
                     /locus_tag="ACIZD4_000258"
     CDS             complement(53469..54800)
                     /locus_tag="ACIZD4_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGC5989224.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(54955..55356)
                     /locus_tag="ACIZD4_000259"
     CDS             complement(54955..55356)
                     /locus_tag="ACIZD4_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HGC5989225.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(55442..55648)
                     /locus_tag="ACIZD4_000260"
     CDS             complement(55442..55648)
                     /locus_tag="ACIZD4_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989226.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(55743..57245)
                     /locus_tag="ACIZD4_000261"
     CDS             complement(55743..57245)
                     /locus_tag="ACIZD4_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HGC5989227.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(57263..57718)
                     /gene="argR"
                     /locus_tag="ACIZD4_000262"
     CDS             complement(57263..57718)
                     /gene="argR"
                     /locus_tag="ACIZD4_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGC5989228.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(57816..58433)
                     /locus_tag="ACIZD4_000263"
     CDS             complement(57816..58433)
                     /locus_tag="ACIZD4_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC5989229.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            58654..60027
                     /locus_tag="ACIZD4_000264"
     CDS             58654..60027
                     /locus_tag="ACIZD4_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5989230.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            60102..61214
                     /locus_tag="ACIZD4_000265"
     CDS             60102..61214
                     /locus_tag="ACIZD4_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC5989231.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(61286..62923)
                     /locus_tag="ACIZD4_000266"
     CDS             complement(61286..62923)
                     /locus_tag="ACIZD4_000266"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HGC5989232.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(63091..63699)
                     /locus_tag="ACIZD4_000267"
     CDS             complement(63091..63699)
                     /locus_tag="ACIZD4_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC5989233.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(64083..65234)
                     /gene="queG"
                     /locus_tag="ACIZD4_000268"
     CDS             complement(64083..65234)
                     /gene="queG"
                     /locus_tag="ACIZD4_000268"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HGC5989234.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(65253..66005)
                     /locus_tag="ACIZD4_000269"
     CDS             complement(65253..66005)
                     /locus_tag="ACIZD4_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989235.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(66146..67096)
                     /locus_tag="ACIZD4_000270"
     CDS             complement(66146..67096)
                     /locus_tag="ACIZD4_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HGC5989236.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(67097..67936)
                     /locus_tag="ACIZD4_000271"
     CDS             complement(67097..67936)
                     /locus_tag="ACIZD4_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGC5989237.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(67933..68679)
                     /locus_tag="ACIZD4_000272"
     CDS             complement(67933..68679)
                     /locus_tag="ACIZD4_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGC5989238.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            68917..70287
                     /locus_tag="ACIZD4_000273"
     CDS             68917..70287
                     /locus_tag="ACIZD4_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC5989239.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(70342..71238)
                     /locus_tag="ACIZD4_000274"
     CDS             complement(70342..71238)
                     /locus_tag="ACIZD4_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC5989240.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(71352..71522)
                     /locus_tag="ACIZD4_000275"
     CDS             complement(71352..71522)
                     /locus_tag="ACIZD4_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989241.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(71519..72196)
                     /locus_tag="ACIZD4_000276"
     CDS             complement(71519..72196)
                     /locus_tag="ACIZD4_000276"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGC5989242.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(72287..73192)
                     /locus_tag="ACIZD4_000277"
     CDS             complement(72287..73192)
                     /locus_tag="ACIZD4_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HGC5989243.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            73367..74791
                     /locus_tag="ACIZD4_000278"
     CDS             73367..74791
                     /locus_tag="ACIZD4_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HGC5989244.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            74837..75868
                     /locus_tag="ACIZD4_000279"
     CDS             74837..75868
                     /locus_tag="ACIZD4_000279"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGC5989245.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            75875..77062
                     /locus_tag="ACIZD4_000280"
     CDS             75875..77062
                     /locus_tag="ACIZD4_000280"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGC5989246.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            77218..78600
                     /locus_tag="ACIZD4_000281"
     CDS             77218..78600
                     /locus_tag="ACIZD4_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HGC5989247.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            78637..78957
                     /locus_tag="ACIZD4_000282"
     CDS             78637..78957
                     /locus_tag="ACIZD4_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989248.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(79157..79825)
                     /locus_tag="ACIZD4_000283"
     CDS             complement(79157..79825)
                     /locus_tag="ACIZD4_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGC5989249.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        22892 a        16757 c        14323 g        26078 t
ORIGIN      
        1 tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt ttgtcaaaat
       61 actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga aaggaaccga
      121 tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg tccgcgaaat
      181 cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc ttgctattta
      241 tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat taggaaatac
      301 tttttttaaa cagcctgttc tagcaatcgg cacaaaattt gctgaaagca aactattaga
      361 attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc aaattggtgt
      421 aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg cttacttgat
      481 tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag gaaacgctgt
      541 ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag aggaagaaaa
      601 aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga ctctcccttt
      661 tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt tgggtggtac
      721 actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt ctgttgtcga
      781 attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg tctatctgtt
      841 tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg atacgcagaa
      901 aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt gtttggtcaa
      961 cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca gcagctggtt
     1021 tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat tcatgaaaga
     1081 aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag tgatggcttt
     1141 actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg tgattctcgc
     1201 atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc taacaacaac
     1261 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
     1321 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
     1381 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
     1441 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
     1501 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
     1561 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
     1621 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
     1681 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
     1741 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
     1801 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
     1861 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
     1921 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
     1981 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
     2041 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
     2101 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
     2161 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
     2221 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
     2281 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
     2341 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
     2401 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
     2461 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
     2521 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
     2581 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
     2641 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
     2701 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
     2761 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
     2821 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
     2881 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
     2941 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
     3001 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
     3061 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
     3121 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
     3181 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
     3241 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
     3301 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
     3361 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
     3421 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
     3481 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
     3541 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
     3601 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
     3661 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
     3721 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
     3781 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
     3841 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
     3901 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
     3961 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
     4021 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
     4081 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
     4141 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
     4201 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
     4261 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
     4321 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
     4381 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
     4441 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
     4501 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
     4561 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
     4621 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
     4681 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
     4741 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
     4801 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
     4861 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
     4921 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
     4981 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
     5041 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
     5101 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
     5161 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
     5221 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
     5281 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
     5341 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
     5401 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
     5461 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
     5521 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
     5581 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
     5641 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
     5701 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
     5761 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
     5821 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
     5881 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
     5941 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
     6001 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
     6061 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
     6121 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
     6181 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
     6241 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
     6301 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
     6361 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
     6421 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
     6481 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
     6541 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
     6601 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
     6661 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
     6721 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
     6781 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
     6841 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
     6901 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
     6961 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
     7021 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
     7081 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
     7141 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
     7201 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
     7261 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
     7321 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
     7381 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
     7441 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
     7501 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
     7561 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
     7621 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
     7681 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
     7741 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
     7801 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
     7861 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
     7921 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
     7981 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
     8041 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
     8101 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
     8161 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
     8221 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
     8281 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
     8341 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
     8401 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
     8461 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
     8521 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
     8581 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
     8641 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
     8701 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
     8761 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
     8821 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
     8881 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
     8941 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
     9001 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
     9061 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
     9121 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
     9181 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
     9241 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
     9301 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
     9361 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
     9421 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
     9481 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
     9541 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
     9601 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
     9661 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
     9721 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
     9781 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
     9841 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
     9901 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
     9961 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
    10021 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
    10081 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
    10141 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
    10201 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
    10261 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
    10321 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
    10381 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
    10441 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
    10501 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
    10561 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
    10621 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
    10681 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
    10741 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
    10801 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
    10861 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
    10921 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
    10981 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
    11041 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
    11101 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
    11161 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
    11221 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    11281 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    11341 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    11401 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    11461 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    11521 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    11581 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    11641 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    11701 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    11761 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    11821 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    11881 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    11941 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    12001 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    12061 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    12121 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    12181 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    12241 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    12301 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    12361 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    12421 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    12481 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    12541 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    12601 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    12661 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    12721 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    12781 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    12841 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    12901 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    12961 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    13021 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    13081 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    13141 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    13201 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    13261 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    13321 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    13381 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    13441 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    13501 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    13561 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    13621 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    13681 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    13741 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    13801 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    13861 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    13921 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    13981 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    14041 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    14101 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    14161 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    14221 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    14281 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    14341 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    14401 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    14461 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    14521 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    14581 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    14641 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    14701 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    14761 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    14821 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    14881 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    14941 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    15001 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    15061 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    15121 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    15181 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    15241 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    15301 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    15361 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    15421 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    15481 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    15541 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    15601 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    15661 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    15721 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    15781 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    15841 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    15901 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    15961 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    16021 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    16081 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    16141 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    16201 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    16261 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    16321 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    16381 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    16441 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    16501 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    16561 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    16621 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    16681 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    16741 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    16801 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    16861 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    16921 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    16981 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    17041 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    17101 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    17161 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    17221 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    17281 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    17341 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    17401 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    17461 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    17521 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    17581 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    17641 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    17701 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    17761 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    17821 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    17881 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    17941 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    18001 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    18061 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    18121 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    18181 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    18241 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    18301 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    18361 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    18421 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    18481 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    18541 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    18601 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    18661 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    18721 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    18781 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    18841 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    18901 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    18961 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    19021 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    19081 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    19141 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    19201 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    19261 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    19321 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    19381 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    19441 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    19501 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    19561 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    19621 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    19681 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    19741 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    19801 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    19861 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    19921 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    19981 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    20041 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    20101 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    20161 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    20221 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    20281 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    20341 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    20401 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    20461 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    20521 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    20581 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    20641 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    20701 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    20761 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    20821 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    20881 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    20941 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    21001 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    21061 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    21121 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    21181 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    21241 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    21301 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    21361 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    21421 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    21481 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    21541 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    21601 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    21661 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    21721 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    21781 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    21841 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    21901 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    21961 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    22021 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    22081 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    22141 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    22201 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    22261 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    22321 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    22381 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    22441 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    22501 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    22561 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    22621 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    22681 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    22741 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    22801 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    22861 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    22921 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    22981 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    23041 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    23101 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    23161 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    23221 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    23281 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    23341 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    23401 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    23461 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    23521 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    23581 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    23641 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    23701 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    23761 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    23821 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    23881 gtgtattcct cccgtaacaa attagaaatc gtttacttaa agtattacct aatttatttt
    23941 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    24001 taagttgttg ataataaaga gatttattaa cgtaaaaaga ataagttttt ttaaaataac
    24061 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    24121 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    24181 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg aatctttgaa
    24241 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    24301 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    24361 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    24421 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    24481 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    24541 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    24601 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    24661 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    24721 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    24781 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    24841 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    24901 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    24961 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    25021 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    25081 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    25141 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    25201 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    25261 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    25321 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    25381 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    25441 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    25501 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    25561 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    25621 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    25681 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    25741 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    25801 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    25861 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    25921 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    25981 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    26041 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    26101 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    26161 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    26221 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    26281 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    26341 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    26401 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    26461 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    26521 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    26581 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    26641 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    26701 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    26761 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    26821 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    26881 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    26941 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    27001 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    27061 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    27121 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    27181 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    27241 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    27301 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    27361 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    27421 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    27481 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    27541 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    27601 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    27661 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    27721 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    27781 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    27841 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    27901 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    27961 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    28021 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    28081 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    28141 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    28201 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    28261 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    28321 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    28381 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    28441 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    28501 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    28561 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    28621 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    28681 acagtttgca gacgaagcat caatacaata caagtcaaaa tggagacgat tggcaatagc
    28741 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    28801 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    28861 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    28921 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    28981 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    29041 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    29101 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    29161 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    29221 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    29281 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    29341 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    29401 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    29461 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    29521 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    29581 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    29641 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    29701 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    29761 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    29821 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    29881 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    29941 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    30001 gattaaactg ttttcatata ccctaaaagg ataccaccta aaatgactaa aaggcaacca
    30061 acaataacat aaatgagctc ttttttcgtt tttctttcgc caaggatgaa aatcccacct
    30121 aaagtagaga taatgatccc catttgtgaa agtgagaagc caacagctaa accaagtgat
    30181 ttgactgtta gaagcatgca gatgtttcct aagccccata ataatccaca gatcatgttt
    30241 ttccacacaa actgatcgac tttaacttta cggaaagcaa agaagcttgc gcctaagatc
    30301 attccgatac tttgaggtaa gataattgac atcgcatcca aattcgccca gttgacgatg
    30361 atggtatata caccataacc aatcgtagag aagatcaatg ctctaaaacc cttaccaaaa
    30421 tcaagcattt tattatctgt atctattttt ccttcgtcat cttgtcgggc agtcaaatac
    30481 gcaccgctta caagaagagc taaagcaata ataccgtata cataatcttt cgtttgtgtc
    30541 cattcatgga agaaaacggc tcccgcaatc gtattcaaaa ttaattgaaa accagtagac
    30601 aatggtagcc ctacagaaac acccatgtac ttcattccat ggaactgtcc attttgtcca
    30661 acactccaag ctaagccgga taaaaatccg atcaagaaaa tccaaggggt gattacagga
    30721 ctaacaacga aaaagacaac taaagaaaac agaaatgcac cgatcgtcat tcctagtgtt
    30781 tgttgattgg catcgccacc aattttacca cttactaaac caatactacc ccatgccaac
    30841 atagggacta atgctattaa aatttccata accaatctcc ttttatttca catgataaga
    30901 aacttatcag cgaaaacgtt aacaacacaa gcactttttt tcgtttctaa cgattttcta
    30961 acgtttttca ttataaaaat ttaagattgg gaaaaataaa gtcattgttg tcccttttcc
    31021 ttcagttgat tcagccgtca aatggatacc taatttttcg gccagatttt ttgctaaata
    31081 aagtcctaat cctgttgaat gtgttttgct aagtcgacca tttctcccag taaatccctt
    31141 atcaaagatc cgtttcaagt cttccgctgg gataccgatc cctgaatctt taactgaaag
    31201 gctgactcct tgcgcttcct tttctatgct cacaatgatg tttccgtgat ccggcgtata
    31261 tttgatggca ttactaagca attggttgaa gataaaagcg atccatttag catcggtcaa
    31321 aacagtatga tcctcaccaa cgatctcgta gcgaatattt ttttggataa aataatttgc
    31381 ctgactgcgt atcacaggct gaatgattcc ttttagtcca tattcttgga tgaggtagtc
    31441 ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt tctacgtatt catcgatttt
    31501 tgataattca ttttctagta atgtatactt ttgatcgtca atatcgaact cgatcgaacg
    31561 aactagcaat ttagaagcgg aaagtggcac tttgatttca tggacccatg agtcaatata
    31621 atctttttgg tcttgttgat tactgattgc tgattgcatt acttcttggt gttcacggat
    31681 cagctgattg atatattctt ctaccagttt ttcttcttct gtcctcccac cactcaaata
    31741 attttgcaaa ggggaagttt tttgtatgtc ggctaatttt ccccaccatc ttctcttgct
    31801 caagtaacca cccagcagat aaaaaatcag aaagacgccc tcaatcaaag ctaaataagc
    31861 aattgtgctc aaatcaactt tgatgtttgg cgccagccac atcacaaaga tcgtcaatgc
    31921 aataaaaaac agccatccca agatcaatgt ccactgatct ttcaaatatt taaaaaaatt
    31981 catcttaacc gctcatcctt tcagggaacg atatatccct gtcctacttt tgtttcgata
    32041 tatccttgga tacctgcctg ttcgattttt cggcgtaacc gattgatgtt gactgtcaat
    32101 gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc gcagcaattt ttcccgactt
    32161 aagatctttc cattgtgctt catcaaaata aataatagac gatattcatt tttgctcaaa
    32221 tcaatgatct ctccgttgat ttccatactt ccgttgtcaa cattcaacgt aatgccattg
    32281 tggctcatca tttcactaga taattctgtg tagttgtaag aacggcgaag taatgcattg
    32341 atttttgcaa tcagtacatc gatttggaaa tgttttgtca caaaatcatc tgcccccatg
    32401 ttcatagcca tgatcatatc catattcgta ttcctgctgg agataaaaat gatcggtact
    32461 ttcgatactt cacgtatttt ttgacaccaa taatagccat ccaaaacggg aagattaata
    32521 tctagtaata caagctgtgg ttcttctctt tcaaagtctg agaacacttg attgaaatcg
    32581 gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct ccatgatcaa ttgtcgaatg
    32641 atctcttcgt cttcgactac catgattttt gccataaaaa atccctccat ctttcttctt
    32701 gctactacaa tatcaaagaa gcccttgtga aacaagttgg cttacctgga aaatgtcatt
    32761 ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat cgcgtttgtc tcttccaagc
    32821 agcttaaatt tattatgtta ttcttaataa ttggtctatt atctgttatt tttctttcgt
    32881 tgtttttgtc ttttaaattt tcgataacac caataaccga aaagcgttag cactagcaat
    32941 atacctagaa ggagtataag taatcgataa agatggtatt tttttgtctg ttctatcttt
    33001 gaagagactt cttctgtaaa gggaactcgt cttcctgtca ctagtaatcg gtgagtgttc
    33061 acggtgtaag gtgtacaagt gataagtgtg actagatcct gcttttctct aattgctaat
    33121 gtatttgttt ttgttggaag gacaacaatt ttctcaacga cttcataagc gagcatccga
    33181 ccatacactt caagatagaa tcggtcatct tgctccattt cttcaagatc cgtaaagagt
    33241 tttttctcag caataccgct atgggcggta atcacggaat gtgtactctc tcctccagtt
    33301 ggaaaagagg tgccttgcag gactgtcgct cctctatcta acaaaagatc attcgtttca
    33361 tcaaataaag gcaagctaac attgattttc ggaatataga tggctccgat catatgttgt
    33421 tcgtaatatt cttttcctgg attttggaca tttctaaccg cttgctcaaa aggatctttg
    33481 acttgtccca ttcctgggat tactgatgta tgagcaagcg tctgattttt cttttcatgc
    33541 actgctaatt gttgctcatg tttttcttct ttatcgcgtt caagctgctt ttgataattc
    33601 tcgatccttc tttgatccaa ataattgctg agagcatctg ctaaaaatgg atatgtaaaa
    33661 actgcagctc cggcaagaaa catcactgcc ataaataatt gtaataaaag actgatttgg
    33721 gtttgaggtc tattacctat tttctttttc attttcttca ccttcttatt taaaaaaact
    33781 gcagcaacct ttataaaacc gattgctgca gcttattttt gttgcttata cttcagactt
    33841 cattttagat ttacggtacc agctgtacgc tccaatcatc aaacttattc cgattagtaa
    33901 gaatgccaag agcccgttcc caccagtagc aggaagtgac ccgcgtttca tattcggtac
    33961 tctttctggc cctggatttt ctactcctac gatctgaatt tcttcattat agcttccata
    34021 agagatgata aattcagtaa aggctgcctc acctgttgga agtacataac cttctggcgc
    34081 catggtctct ttcatttgat aggttccata atctaaccct tgaacctcaa agtatccatt
    34141 tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc cactcaattc tatctgctcc
    34201 tgattcataa acagctaaag gcgactcccc tttataaaat attgcgtatt cagaacggtc
    34261 ttcattccac aattcgaatc ttgcatcttt aagcaattca ctgcttgatg catcatattt
    34321 ttcaaacttt cttccacctg ttgtgacttt ctctggcggc tctactcctt cttcataatc
    34381 aaattcatca tttcgtccga tttcaataac cgctgtgttg ttatggaaat catccgcttc
    34441 tagttctgtg gaaaccttca aattatacgt gatcgttaaa tctcctccac gtgcatctgc
    34501 taatctacct aaagtatcta ctttggctac tccattttct tctgtcaaaa tcgtcacgac
    34561 aaacccgttg cttactactt ctactatata atcttgtcct tttgttaaaa tcgtctcgcc
    34621 ggctcgcact tctatttcct gatcataata agttagacca actgtaggcg tatctgtgat
    34681 tttgtaattt ttgataacag cgcttccgtt ttcaaggaca gaatcgatga aataaggaat
    34741 aggtgctgtg atcgtgtaag aagccgtttt tcctctttct agatcaatat aagaaatcgt
    34801 ttcttgttct ccagcttcat taataatcgt tacttgtcta aggtcgcttt cctctacatt
    34861 catctgttta tctgcttctc tgatttcgtt tttcggatac aaatgcacat ctgtattgta
    34921 tgtgtctttc catgtagaac catcccacac gccatccacc atatcaggca tcatcactgg
    34981 catcataaca accattggag acgcgattct ggaaatatga gctggcgaat aagtttctaa
    35041 gaaaagatag actttatctc tagaagaagg tgcttcttcc gtcacttgga cggtagagaa
    35101 taccgcttct ccagcttcat tcgttgtttg tttgtcaata cttgtcagtc gatattttaa
    35161 aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc gcttcggcag aattaagacc
    35221 gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa tcgtaatata cttccgttac
    35281 gtcaaacaaa tcaaaatcga ctcctggaat attttcttca ccaaaatccg tagaaaccaa
    35341 tccgctattc ggtcgttctt ccggaacaga tgagaaacct tttttgtgta atgtaatcgt
    35401 cacttcactt ggtttttgtg cgacttcttc ggctttgact agttttccgt tcccgaaaat
    35461 ccctattccc gcagtaacga gtaacagtac actcattccc gtgacaatca tttttttatt
    35521 catttttttc tccccgttct ttttttatta ataaaacagc acctaacaat aaaagaattc
    35581 ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg gaatacggac cattttcctg
    35641 attgacctgg attgcttgga ccactcggct ctttcggttt gtccgttgtt tcttttacgg
    35701 tctcgttata aacacgtggt gttgcggatt cataggcaga gactggaact ttcccggatt
    35761 ctaattcagc catctcctgt ccgttaacta ctacatattg tggttggcct tttgcatcca
    35821 cccaaaattc agggatgatg acctcgattc tcttacttgc ttcatccatc tcgtaacctt
    35881 ccacaccttt taattcttca aaataatagg tgccagaagg caagaaacgt tgtcctgtcg
    35941 taacaaggcc ctctttatcc gaaatgaatt tgcttacatt tttgtcattc aaaggatcat
    36001 tgtctgctgg tttgatccat tgatttttca agtcattagc aggagccata tctaaataat
    36061 atttcccccc ttctatcatc tgatatagag caaaaacagc accttctaat ggttttcctt
    36121 tttcagttgt tcctctttga cgtccatact tgaagaagta tggatctctt agataaccga
    36181 catttttagg atagatatga atctcttgca gttcctcggt tgattctgtc gggtgataaa
    36241 ttggcaaaat agcagcaatt gggatagctg tctgatcgat atcaacatcc aatccaactt
    36301 ctggatcaat cgattcttcg aaaatcaaat aaactgcatc ccgatcttgg tttttcttag
    36361 gtgctttgat acgtgcaatc ccgtctccta atccgccaac cgtatctttc ccagttgtta
    36421 ccgaagtccc tatttggaca agcctttctt ctgtgattag ctgacggata ttgtttctgt
    36481 tcgtttcagc gatttgctgg acgaattctt taggagtcat gttttcagca gctttttttt
    36541 catgataata atcggtcatg tcgtaaatgg caaatgtcgc tccatttagt ggcaccgtct
    36601 gtgaaatgat atctgctgtt tcccctgctt cctcagagat agccaagcca tcattttcat
    36661 ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat ccgtttatgc aacacgaatt
    36721 ccacgacatc ttcccctgat tcttctgccg acatcgcatg tggaagaagg actgctgcaa
    36781 gcggtagtaa aacaagtaat tgaagcatca aacacaacag ctttttcatt accttgctcc
    36841 ctccttttta gattgtctga caaacaaacc ataggctgct cctgcaagcg ccatgaagaa
    36901 tgcagcaagc aggatataga ataatcgtcc ggatcctcct gtagcaggca acggattttc
    36961 aggatcgttc ccgacactaa gctgtaatct gattcgattt gtctccaaaa gttcatattc
    37021 taactcttgc tgtagatcag gcgtctctgc ttcttcgttt ggataatacg aaatctcaac
    37081 ttttagtgta cccgcttctt ttcctggaac tacccgatca ttttctatgt caggttcttc
    37141 tcgataacta atttctaaaa taaagtaacc tggaagtttt ctatagctgt caggtgactt
    37201 cacttccttg atccgataga ccccttccaa caagtctgaa gcattgaata gggaagaatc
    37261 gtttggatct ggtgccaagc ctccctcgat gatttcatac tctcctgcac tattttgttt
    37321 ctcaattgaa aattctgcgc cttcaagacg tcggctattc atactgtcaa ttttcaaaag
    37381 ttccaaatcg attggcgcta gttcatcttc taaggttact tgtagtacac catcgatgat
    37441 ttcatagcct tccggcaagg gagcagtttc gtcttcgatg accgtatctt caatgataaa
    37501 cttaccttct tcattcagtg caaactggaa cacttgatca gatagccgat acccatttgg
    37561 tgcgacagat tccgagacct catattcacc aatagacaga tgcagaggtt ggtcgtaatt
    37621 taaatcgaca tacttttcta ctcctacggc acgagaatag aagtatccga tcccaggcaa
    37681 acgtttcgat tcttctggtt ctaacggatt accagtgtat gctcgataca gcgggaagga
    37741 agaatccccc actttcctga tatcgaaacc tgcaccatct aatgtatggc cttcatggtc
    37801 taattttcta actcggatct cccgataatc aaacgtattg taagcagtga atgctaccca
    37861 taaacgatcc tcttcatctg ttgtatacgt gagatattgc caattttctt cacctgtttg
    37921 cttgagttgg atagtcccta tagcattatc gtaaagtcgc aagatccatg tgtcattttc
    37981 atcaggttct ttgaaacctt ctgggttctg gctctcaatg attttgtatt ctgcatagtt
    38041 ggtagtttct tcactatcct tataaacaaa tgaatctggc tctccgattg gatgaataac
    38101 tttctcacca tccacgatta catatttccc gtcttcatct actgaataga acgtgagtct
    38161 ccctttctct tcctctactt cgttcacacc agaaagccct ttcgctactg gatatccgat
    38221 ttccagtccg ttaccatctg tttcataaag ttcaaactct gcgccattga ttggcatatt
    38281 actgccttca attagtttat tgatattcat gtggattggc ttgaattcat ttcgcatttc
    38341 cagtttgaca tacaactcat catactctgt gccttctatg ttaggctctt gtacaacaga
    38401 aagcttgtga tattctcctt cataatagga attcggatct ttaccttccg gtccgccgac
    38461 tctcgaacca gatgtatatt catctacaag ctcgtagtga cctaacatct catcttcgtt
    38521 ggctgcatat tttttgattt ggaattgata cgtctcatct actaactgat aacgtggtgg
    38581 tccagcgatc tctctgatcc aaaatatgtc gctgactgct ccagtttcat ctcctaaaat
    38641 cggcatcttc gtttcaaaga tcgctattcc gtccgtggta gttttacttg tttcgattgg
    38701 ttcggcttcc ccactctctg gattttggtc atataatgca aattcgactc cagccaacgg
    38761 ctcgccattt tgacccttct tgctgacttg gaaattacgg cctttatgtt cgtaacgaat
    38821 ggaagaagat gggaaataca tccgtccagt agtgatatca ttctcataat cctccaggtt
    38881 ctgaatatag gccatattgt tcactgtgca aaaatttccg tcttgagctc ccgcatcaag
    38941 ttttacttgg tacttgatcc tgaccatttc cccttcacct aaagaaatcg gagaaaattt
    39001 ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc gccactactt ctggtggggc
    39061 ttgtccatga cgttcttcat cccatatttc tggctcttgg tacttcatgc cgttttctcc
    39121 tggatctaga tggtaaaact gaatatctgc cgatctgcca gctccaaatg gtgagacatt
    39181 aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt ctcttgaagg tagaagagat
    39241 atcctccaag gctgtaacaa tgtcattctt gttgttcgca ttgtaatatc gcggtgttac
    39301 gccatcttct tctaaatcag caatattttt caatacattt cgtccaatag catctagtcg
    39361 ttgtctcccg ctaacgtttc catcgattcc taaaccaatg gagaagatac ttggcgggtt
    39421 ctcttgatac ttgtttttca gccaatgatg ataagcaact gtgttgatcg cagatgactt
    39481 ttcttgcgaa gtaggactgc cattcgtatt gttattagaa gaaccatcac caacccagtg
    39541 agtcgcttta ttatctcctt cttttacctc tccataacga tagtgtacat ttacttcatc
    39601 ttctggacgg ttaaagtcag atgcataggt aactggatga gtaaaccctg cattagaagt
    39661 attcccagaa aactcctcaa aatttctgaa caaaacgtca ttatcttcag caatcttatc
    39721 ttccatcaca gtccagttgc tccaagctcc attagtgctc gtacgataac ttgactgaat
    39781 cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg attaggattt tttctggatt
    39841 tctattttct ccgccattgt ctttatacaa tgtttcatag ccatttttaa gccctagtgt
    39901 aagcggagtt cctccgattg gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg
    39961 attgatatca tttgtcaatg gaaagatgtc cgaactgatt tgctcatggt tattgatagc
    40021 tgtactatta tggtaaaaat tcaccatacc gattcgaata tccagactcg ggtcagagag
    40081 cagatcttta ctcatttcgt ttactgcctc aatcaacgca gcatttttag tttgactatt
    40141 ggtcccagcg gttaattcac tcatactcgc tgacttatct agaacaaaaa cgatatcgat
    40201 tggactgatt tcctttttct cgcccccgat gacatctaga tagacattgt aaagggttgt
    40261 tgcatcttca ggatgtagat cagatgctgt gctgcttggc agaacaggtt ctacccattt
    40321 tttgatgtac gccccgttat aatccaagta actgttttca aaattccgtt catttcccca
    40381 aagctgaacg gtttgagctg gaacgtttct atcttcttcg cctgcagttg atccattatt
    40441 agtagcatag tcgtaatttc gccagttcgc tcccccgttt gtataatcac tatcatcgat
    40501 caagttctct ccgtcatatg gcgagccttt gtctccttga tagcgttcat tgctttgtgt
    40561 ccaatttcct aacacttttg tatagtcatt cgttgtaaac ttcgggtagc gatgctgttc
    40621 gttttcaact tctccgctag gatagatata ttcatagggg tcttgcgtag ctgttggccc
    40681 aagacgctcc aaaataccgt tgaataactg gcgttgaatg cgctggagtg cttgaccgct
    40741 gggtacgatt ggttcgtcca gcttttccat ctcattttct tcgctacgtt gaatttcagc
    40801 ggaatcttct gtatcagttt cattttcttg taattcttgg ttatctattc tttcatcaac
    40861 caccacttga agaggtagtt acccttcgtt cacatcgggg atcttttctg tttcaaaaat
    40921 caatgtgccg gtttctgctt cttttgaata aacttttccg acataccatt cttgaccatc
    40981 gatcgtctcg acttttaggt cttctccatc ttcatcatag gaggatagac ctgttccacg
    41041 aacgtttttt acggtaccaa tcccggcggc tgccgcatcg attgctaaac gtattctacc
    41101 ttcattggca ctttcctttt tttcaaaagc cagatgccat tcaagggttt cttctttttc
    41161 aatatacttc ccttcaattt ttgcatagtc ctcatctaag aatacctcat cctcctttgt
    41221 ttctgttgac tcagcagcta catccagggt cgtcatatga tagactgact ggaaatatgg
    41281 tccaaatagc aaactgacag ttactaactg caaaagcttc aattttaacc ctttcacatc
    41341 cttatactcc tttcaaaaat atttgtcttc tttcacaaca atcaacaaaa caatgcccat
    41401 ctaattataa tttaatttaa ttttaatttt aaatcaaatg atatcctttt tagttaaaaa
    41461 acaccaatta tacaacattt attattaaaa ttaaattata aaattttata acgttctcat
    41521 ttaacaaaac ttaagttatt aagacaaatg aataaacaac tacgctttcc tcgaaacaaa
    41581 aaaataaagc acaaatgcgc atttacgcac tcatgcttta ttcgtacaat taattcagat
    41641 aacggcagcg cataggatgc caataacact tcctaaaata gctcctccta aaatgtcagt
    41701 aggataatgt aaaagtaaaa aaatcctcga ataagcgatc aaacaagcaa ataaaaaggc
    41761 taatattcct gcaactggac ttaattcgaa caacgcagct actgataaaa aggctagcgc
    41821 tgtatgtcct gaaggaaaag aagaagtctt cggtttactt gtgtaaagga caagccgacg
    41881 atttttttca taaggtcttt tccgtcttgt cgtttttttg ataaaaagca aaccaacaaa
    41941 aaaatagatc aaactgccga taagaatggc tagaccatat tctctagtat caggtatcaa
    42001 gactaaaaca gcagcaagga gcaaccaaat aaaaccacca ttagagatat tactgataaa
    42061 tttcaaaaaa ttgatttttc gactatccgt tttccgttgc ttggcgaact tgttgataat
    42121 actatcatcg attttagcaa tcaaacgcaa catgttattc ctccttttta agaacctttt
    42181 cttgcgtacg atggataaaa agcaggactt gaaaataaaa caagaaactg aaacctaata
    42241 aagcaaaata gattggtcct gcaaaccaga atgcgacaag aaggatcaac gtgcctgcca
    42301 aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa aaatgcagta atccaagaag
    42361 cttctttttg ttccagttga agcaagattt tgtaactaaa gagaagcgcg cttaatagaa
    42421 gcaaaaacaa cgtagtatac atcaatgtat agccaattcc cccaccccaa tagcggaaaa
    42481 tctgataatc gatcaataga agaagaaaat aaacacttgc taaactatct tgctttccat
    42541 aaagagagaa gttctcacga aactttttcc agaatagtga accgagcttt ttctcttcat
    42601 tttttttgta atgataaatc atatacagaa ctgttcgact tgcagttcct aatgtgaaaa
    42661 caggcaagac gcacaggaac catagtagct gtaaatggat aagacgtgga atccattcaa
    42721 tgatttctaa gaaataatca ttggcttttt taccaatcga tcgattcatc atccttttga
    42781 acctcctgtc aaatccatcc cttcaatgaa ataacgttgt gcaaaaaaga acagcaaaat
    42841 cgtcgggatc aagacaagtg ttgctcctgc catcagataa ttccattgtg tcgttgcttg
    42901 gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt tcttgatctt ggatatataa
    42961 cagaggacct aagaaatcat tccaagctgc gttgaaggaa ttgatcgcaa tggtaatcaa
    43021 ggcaggtttc gtcaatggaa gcatcaaatg actccaaata tacaaatgat tcgctccgtc
    43081 gatttcagca gcttcgatca attcattatt gatcgataag taaaattgac gcatcagaaa
    43141 tatattgaac gcattgccga agaacgatgg aacgatcagg ggcaaataag tacctaccca
    43201 gccgatcttg gagaataata catattgagg gatcatcgtt acaaaccccg ggatcatcat
    43261 cgtagaaaga accaaagcaa acatcagctt tttcccagga aaatcaagct tcgcaaatcc
    43321 ataagcaata aaagaatttg aaaggacatt accgatcact actagcacag tgatgaataa
    43381 tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc gtatccagat agttttccca
    43441 tacgattttt tctgggaaaa aggtcggagg ataacgaacg atttcttcca ttggtttcaa
    43501 tgaagtaaac accatccaaa gcaatggaat gatcaaaatg attcctatta ctgtcatgag
    43561 gacataactt agtatttttt ttgtttgccg attcacactg gtctttttga aataatccat
    43621 catttgccgt cacctccaga ataatagacc cacttaggtg caagcttcaa attgacaaac
    43681 gtcagaacca acacgatcag aaacaggatc attgacatag ccatcgcata acccatatca
    43741 aaagctacga acgccttgtt ccacatatgc agattataaa aaagcaaaga atttgcaggt
    43801 ccgcctgttc catttttcgt catgacataa gcttcttgaa aaatttggaa agaaccgatc
    43861 gtagaggtga tcacatcgta aaaaataata ggagtgatta atggcaaagt aatacttttg
    43921 aactttcccc aaacgcctgc tccatcgatt tctgctgatt catataaaga tctaggaaca
    43981 ttttgtaatg tagctaagta aagtagcatt gctcctccag aactccatat tttcatcaaa
    44041 atcaacgcag gtttcgtcca ttgtggatca aacagccaag ctggtccagg gatatggaac
    44101 cagcccagaa atgtgttgat caatcctgca gatggagaaa gcagctgcat ccataagatg
    44161 tagactgcta ctcctgataa gactgccggt aaatagaaag ctgtacggaa tacactgatt
    44221 cctttgattt tttgattgag tactgtggct aaaaacacac tgaaaatcgt cgtcagcggt
    44281 acattgaaga tgacgaaata aacggtgttg tataacgatt tccaaaataa atcatcgtga
    44341 acgaacattc ttttgaaatt tgctagacca atgaaattca tcttggatgt caaattataa
    44401 tcggtgaaac taccaataac tgaaaaaagc ataggcccta gcataaatac caagaacccg
    44461 ataataaaag gcgagataaa taaataggcc catcttgctt cttttttctt tcggatagat
    44521 aaacgcttca aattttcttg cctcctctgt acctagacag tcaaaaatgg attattgatt
    44581 ttgcttgact aagttttcta ctgctttttg tgcatctgcc aatccttctt ttggtgattt
    44641 tgttcctaaa agaatctggt caatctgttc attcactaat gtcgtgtaat ccggagcatc
    44701 taaaggaact ggtgtgatca ccgtattttt aaagttttcg tccgccattt gatagatcat
    44761 ttttccttta tccgttaggt tgtcattatt cactaaattc tcattggctg tcttgctcgc
    44821 catgatatca aaactttttt cgccgaattt ttcttgtact tctggagaag aaagatattt
    44881 gatgaattca taagaggcct caggatcttt tgctccgtat ggtacttcca agacgaatcc
    44941 gccaccccac gaccaatggc ctgaaccttc ttctttttct gggagctgca tcacgccaaa
    45001 atcaaaatca tccggtgcat tttccatcaa actagagtaa taattgatat tttgggcacg
    45061 catggctact aatccggaaa taaatggatc agatacacca gacccaaatt cggcttctaa
    45121 tttattgatc gtatttttcc cataataatc ttgccagtct tggatccact ccaaggcttc
    45181 cactttattt ttagtatcaa tcttgacttt ttcatctttg tcaaaccaac tagtcccgtt
    45241 atctgcgttt agcgcccata catcagcccc taaattccat aatggataaa aaccgatgcg
    45301 tgtaaattct tttccttctt ttttatctag tttacgtgct gtttcttcta attcatccca
    45361 agttgtcggt agatcttgtt cactgattcc agcttcttta aataactttt tattataaaa
    45421 aatgacttgt gtatctgtat tgaatgggat cgcataagga tcaccttcat attctactgt
    45481 atcccaaagc tgcggataaa aatccttaga agtgtctttt tctacatatt tggagagatt
    45541 agttgcttgc tgtgcttctg ctctttgggc aacggaattt atgtcctgta caataacatc
    45601 gggtgcattt ccagctgtta ttgcagataa agatttagtc cagatgtcac cccatggctg
    45661 atacttataa tttacatgga tctcgttttg tgattgattg aaatcctcaa tgatttcttc
    45721 gatagcttct tttcgtgcac cggatcccca aaaggaccag aaatcaatat tttttcttcc
    45781 atcacttgtt ttttcagaag aatttgctgc acttgaactg gcatcgcttg cattacttga
    45841 tccgcatcct cctaataaaa acaatgctga acttgccagc aaccctgtaa acaataattt
    45901 tttcatattt tacctccaaa ttttaatgta accgatgccg gttttaatat aacgatatca
    45961 ttttgttctg aaaataacaa tttataaggt atgattctaa aaaaattatt aatgatacca
    46021 atactttata taattcgcga gcgctttctt tgaatttttt aatctttcgt agcagaatga
    46081 gaatgtatta aaaatagatt aggaggaatt ttgatgttta gacaccagaa agaattgcag
    46141 tttgaagcaa aaccagatcg tccgaatcca ttaatcgcga aatatctgca ggagctgatc
    46201 ggcggccaat atggcgagat gagtgtagct atgcagtacc tgttccaagg ctggagctgc
    46261 cgaggagaag aaaaatataa agatatgctg atggacattg caacagaaga aatcggccac
    46321 gtggaaatgt tggcgacaat ggttgctcgt ttattagagg gtgcgcctgt tgaagatcaa
    46381 gaagcagcga tgcaaaaaga tccaacaatc ggtgccatta tctctggaat gaatccacag
    46441 cacgcgatcg tagctggctt aggacctcgt cctgctgaca gcgtgggcaa tccatggagc
    46501 ggtgcctata tcattgcgag tggcaacttg ttagcagact ttagagctaa tttaaatgcc
    46561 gaatcacaag gaagacttca agtagcacgt atttacgaaa tgatcgatga tcgtggcgta
    46621 aaagatatgc tgtctgttct ccttgcaaga gatagctatc atcaaaatct atgggaatgt
    46681 gcagtgaaag aattagaaga aaaagaaggt tcaatcttag tcccaagtac tttcccgcgt
    46741 gacaaagaac gaaaagacat tgcttatgac ttctataact tctcagaggg agaccaaagt
    46801 agtgaaggtt cttgggctag tggcaaagca ctggatggcg aaggcgaata tcaatggttg
    46861 aaagaaccta agatcgaagg cgctgcacca aaattagaac cagtaacacc aaaaatgtat
    46921 gggacacctc cattcaagaa ataaatatct acccgtagaa acacccgttt tttgttccac
    46981 acgctttgtg agcaaaactg actaaagtca ttaatcataa ccacccttca aaagggtggt
    47041 tttctctaga gctataagct caaatcaccg gccagcgcct aaagacgctg gctttcatat
    47101 tttatgttca agccatattg cctttgccag ttttgcccac ctcttaaaag gtttatgtac
    47161 tactccttag cccttaaaag gatcgtctta ctctcgtaca ctcagcttat ctaacgcact
    47221 atcatgtttt tcttgttctt gaatgtactt tttgatggtc gcttcatttt gtcctacttt
    47281 tgtcacatag tatccttcca cccaaaagtg tcgataccca aatttatatt ttagatttgc
    47341 acaatctctt gatgatctcc tgaatattgg ctcgatattg attataaatt atttttcttc
    47401 tatactttgg tgtgaataca atgtggtatt tacacatcta ctttgtacgg gctaaactat
    47461 ttccctttat tgctccaccc gcatagcaag tggttttgta tttcaatcgc tcggcgcgct
    47521 caattaggtc taaagacaat aaatctaaaa acccgctgct tcactgacag aaacaacggg
    47581 ttttcagaaa aaaatgaaat gaaaaagatc tcttacggca atctatttta tttttttgat
    47641 tttttataaa tggaaaatgc ttcaagaagt ccaagaaata aagccgtata aaaacaagaa
    47701 cctatgaaat ctttatttat tagatattca acagaaatcc cgataacact agccaacaat
    47761 atatttatca gaagtgtaaa ataaggatgc tttttataga atagaactag tgttgttttc
    47821 atagactctc ctttcttcat atttccaatt aatcacaaat tcacggcatt actagaaaaa
    47881 ttaaaggggc gcagaagtgg aaaaatactc ttcgactttc cctacaaacc aggccatctt
    47941 gtgtttaata actataccaa atctaaggta cctctaaatc taaattccat ttgtggcggt
    48001 gacctccaat ttttaactct tctatctccc atccagtata cataaccttg atacttcgac
    48061 cacttatata tcgaacacac aaatacctat ccattgcagg agtactacct aacttagttg
    48121 ctacttgcat ctaaataaca gctgaaaaga taggacttac tcttagtaaa gtatctgaac
    48181 tattaatttt taaactatca tttttatcct caactacatg cacatctgtt gcaacttcac
    48241 tttctgtctc atccagataa atgattaagg aatcgggaat tgcaatatct tcagctgacg
    48301 ctggaatagt tgagctaaat tagtcatcat atctttatta taaaataacc aacagcaaaa
    48361 aatacaatga aaaacaaact tggaactaat gtatcattaa taaatgttga aaaattcagc
    48421 aactcattac tgtatgattt tagcagccca accaacatat accctataaa agctaataag
    48481 atggttagga atcctttaga atttttactc attcatagac acttccttaa ataactttta
    48541 ttatagaagg tattgtaaat aataatattg acaaaaagtg actcaaaata aaaaaaacct
    48601 tacattatac tggaatgaac tgtattgata gtgtacctaa aagctctact gacataagat
    48661 cgtgtaatcg gtaaagtaat tttattaatt atacgggatg taatcaatta gagaataaac
    48721 taatcataaa aggtactttt acattcataa ttgtcgcttt gagattctac tttggttcac
    48781 tatctgaccc aattgcacat tttcgatcat tacaagtatt ggtgtcgtta gaacaactaa
    48841 ataaaaacta gcggtagatt tttcagaatc tatgctaatt tctgtatgga tgttccagtg
    48901 atggcaaatt tctcttttca ttgtttttct tgtcgcatga tatgcctttt tgtgttattc
    48961 agttaaacta tagaaattct ttcctagaca gatcttgatc ccaaatttta cgtttttgag
    49021 catcgatata gtttaaaatg acattactca tatctaaaga gtttagattt tttaggacta
    49081 aaactgtcag ttgttctttt tcttctttct gttaaagtat tgtcgcgact tttcgtatac
    49141 gttaagatat gtcgtgaaaa aacaagtttt gtgacacaaa aaaacgaatg acttgaggaa
    49201 atcacctcaa tcattcgttt aaaatgctat atattcttta gtttaagata cggaaattaa
    49261 tgccatcgac cacactagta gaatgaacga catttacttg gccttttttt aatttcgtta
    49321 tgtttagcat ataaaaatat tatagagttt acttacaatg cttaaaacat atactgtata
    49381 atctgatcaa ttttagccat gtcttgcaat ggtaagtttt ctattttttt gagttttcgt
    49441 tccttaaaat caagagattt taattgtgta ataattactt gtccttttat atctagctct
    49501 tcaggtaatg agtaacgtgt cggtaaattc tttatagtgg aagtaattgg acatatgacc
    49561 gaaaacattg ttttacggtt aaattcataa cgagagacga ctagtcctgg tcgtcttttt
    49621 tgaatttctt ttcctacgga gggatcaaaa tcaatccata caatatcacc ttttttagga
    49681 atataaattc tttcttctga cactataaaa tttctctccc ttcaggagtt aaatcttccc
    49741 attcgtcttt ctcataatac tcggcctctt ccccaccact aaatggatct tcaatttttg
    49801 gaactaacgt aattgttcca tcatcagaat acacaacgat atattcttgg ttttctgaag
    49861 gtttctttcc gttatcagaa ggtaaagtta ccactacaga acttccttgt aatctagatt
    49921 ttgtaacaag cattatcatc actcccttaa taaaagtata ctatataaca ctaagtaacg
    49981 caaaattccc ctttgtaaac tatctagaaa attgttttgt ttaaagtata tcttattgga
    50041 tataaataga aataaattgt agccagttca ttttttcttt aactaaaaaa ataatccaag
    50101 aaacattgaa cctatggatc caaaagctac ccaaatacta tagctaaccc cccgctacct
    50161 tcaattttgc agataaaacg ctttgggaga aaatttcaaa gacaacaggc catcctatca
    50221 tgcccgatta taaacaaaaa gctggctatt ccttttgctc tgacaaattt caattgggaa
    50281 agttcacgaa actagcaggt gaagaagttt caactgttcg gatcaaagaa tgcccgcttc
    50341 aaatagaaac attggttcaa cgaatttcaa ctagacaaga ctttgctatt gtagaacgtg
    50401 agatcgtagc tatttttgta gaagaaggga ttttacatga tccaactcat atcaatgtgg
    50461 ataaatggca acctcttatc tataaattca gagaatatac aactgccaac cagtcgttaa
    50521 ctttgaattt tagattccaa gaattcaaag agtcataatg ataaacatcg ttaggtataa
    50581 ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag ctatacatta gaaaggtcga
    50641 ctgtgaccct atagatgcag tatatgcagc ttatgagcat ttcttctgtt ctctttgttt
    50701 ttgggatctg tgctgaagtc tttttcgttt tttgccgctc tttctttgaa aaatcgatta
    50761 tgttatacct tctccattac taattcaggc atctgctgag taatgatttt tcgcgcaaaa
    50821 gaaatatctg ttacccaagg ttcgatttgt tcttcagtca agacaagcgg cattcggtca
    50881 tggattggtg cgactgtgcg gttaggttca gtagtcatta tgattgattc tgccattttt
    50941 tcatcctgat ggctacgata aaaaccgcca atatacacta ttttttcctt atttgaaaac
    51001 ataaatttgt ctttttcttc attccactca ttgggaaaac acaacgattt tgcaaaaatg
    51061 gttgatgaaa ggtctttttt tcttctactg tctctgcacg ggcattaatc atcaattgtc
    51121 cttttttaaa tccggtaaat ccccacttca tgatttccgg agtgaggatg ttttcttcct
    51181 cttttcttaa cgtcacaaca agatttgacg gaaaaacttc tccagctgct aattctgctg
    51241 cctgcttcgg ttgtttcgtc tgggcttctc gataataatt ctgaaggagc tctgactcta
    51301 gatcaaaaaa ataacgacca cacatcctaa tccctcccaa tctttttttc tatcatacac
    51361 tgcaacaaga agttcgcacc aacaaaacgc tttcaatttt tgtagaacta aaaaagttgt
    51421 gacaagtgac aaactctcca gtgaatggta ttctcctgcc aactcctcgg tcacaagtca
    51481 caatattcaa caaacatgag aagctgcttt ttgaaattgt tccttgtgac tcggagtgaa
    51541 acggcaggct tacgacctct gggtaaacgg tgttcaaaag ccagtttctc ggtattaagc
    51601 caaatttatg caaaaatgta gaaagctatt ttcacaaaat ttttcttaat actcgaaact
    51661 aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat
    51721 aagcccaacc aaacgaaaaa tatgagcagc tatttttatt tggctgttct tattacttga
    51781 tgcagggcag ctttttcaca acctctccac taaacggtgt tcaatcagct aaccttcggt
    51841 attagctcaa aaaacggcaa aatatgagga actattttgc cgtttgtttc tctaatactc
    51901 aggtcaaagc gctgatttca caacctctaa tacacggtgt tccagaagta gcttcttcga
    51961 aaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt
    52021 cttgaagctg accacttctg tcacaacctc taattattaa agaacctttt gcgaagttaa
    52081 caatctttct ttgatcaatt gaaaattctg cctaagtagt gatagatcct gtgtgacttt
    52141 caacaataag atacttccct ggatttcagc aatcaacgct ttggcttgac ggtctgcttc
    52201 ttcatcggac agtttttctt cagaaagtgc caggatattt tgtttcgtat acttgaccca
    52261 ttgattgact aattctagta gcaacagacg gtattcttca tccactgtac tcaactcaat
    52321 aatcaaatta cctacaggac agccatgata agtgatctgt gtctcatgat cagcgaaaat
    52381 ccagtccaac atttcttcta atgcttcttc tggctgtttt ccagcattta agatgtcttc
    52441 gaacaattct gtctgccata cgtccatatg cgcatggatc accgctagac aaacttcttt
    52501 ttttgaagaa aagtaataat aaaattgacc ttttcctgta tcagaagctg ctagaatatc
    52561 tcggattgac gtttcatgat agcctttttt ataaataaga tctttggtcg cttccaagat
    52621 cttttccttt gttttcaatg atattctcct ttttcatttc tcatagtcct atattataca
    52681 gtaaattcat cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca
    52741 cagccctcac tataaaactg ttctcatata gctagatgtt cattgattca agaactgcga
    52801 ggacaaaagc aattcctatc ttatgatagt tgctctaata cttcctctgt tgtcatcact
    52861 tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg gccaggagca
    52921 ccaattgcat ctgtcgctac cacaacattg aatccactct ctaccaattc acgcatatgg
    52981 gaatcgctac acaagtttcc gttcattcca ccaagaatta ctgtgtcgat tccatttttt
    53041 ctcaattgga gcgccaaatc attgctttct ggtccaaaga ttttatgagg agagctgatg
    53101 atcgtatttt catccaaata aggtttcaat tcttcgataa aatcggctcc tgaaccttct
    53161 tccactgatt catattgact ttttctagca aacatctgct gctcaagcat catatgttct
    53221 cctgcaccgc caaattgcca tttatggtca tgtgggtaaa aataatgagg agaaataaag
    53281 agtttgtatc ctttttcttt tgcttgtttt accatttcaa tcatattttc gatcgtattg
    53341 tatttttcta agatatcttt tgtcaaacca aagccaccgc ctgctggttt caagaactcg
    53401 acttgcgggt cagtgagaac tactgctgta tttttattat tgaacatggt ggattctcca
    53461 ttcgttattt attttaatac atcatttaga gcttcactca ttgtcggatg agaatagatt
    53521 tgatctctca ataacgtata aggaagtttt ccattcatag ctagcgaaat caagttgatg
    53581 acttcatgag aatcttccgc atagatactt gcccctagaa tcaagtcagt ttcagggtcg
    53641 actaaaactt tgaatacacc tttaggatct tctaatactt gtgctttagg gacaccgctt
    53701 gtcatatact tgaataattt gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa
    53761 cctacattgg ataaagtcgg agtgataaat acactgtaag gcacagcttt ccggttattc
    53821 gttgttcgtt tattctcgcc cttcaactga tccataatga ttcgataatc atctagagag
    53881 atataagtga actgcaatcc gcctttgacg tctccaatcg cccaaatgtt gtctgcatct
    53941 gtacgaaggt attcatccac agcgattgct ccgcgatctg ttagtttaac atctgtattt
    54001 tctaatccaa gtgatgctgt acttggtttt cttccagttg cagccaaaac ttttgacgct
    54061 tggattgtta cttcttggcc atcttctgta aaggtgacgg cagctgttga ttcttggtct
    54121 gctacttgat ctacagatac acctagatgg aattcgattc ccgcatttgt catgtcttct
    54181 aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa attcagaatg ggcatcaaga
    54241 acgacaactt tagatccgta ttcattgaac attgatgcaa attccaagcc aatatatcca
    54301 gccccgatga tcactaattt ttccggtaat tgttcctgat ccatcgcttg cgtagaatca
    54361 atcaagtagc gacttgtatt caatcctttg attggtaaaa tgattggttc agaaccagta
    54421 ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac cattattcgt cacttcgatt
    54481 tgatggttag aaagaaaacg tgctgtaccg tccatcactg tcccagttgc ctcatcgctg
    54541 atcatatgat aatttttggc gcgaagcatg cccgtcaatt tttctttccg agcaacagcc
    54601 tctgtaaagt cgattcctct ttctccattg aaaatcaatg atttagaagg aatacagccg
    54661 atgttgatac atgttccgcc atacatacgt gttgactttt caacgactaa aaccgattca
    54721 ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc gatcacaata
    54781 ttttgatatt tttccatcat ttttccctcg cttctttttt acctaccgat tggtacaaaa
    54841 atatgataac cgataattgt ctattctcca aatcatctgc tttatttgtc aaaaaaaacc
    54901 agacaaaaag cggtcctttc acgtttttag tctggttcga tttcctttat tcttctaaac
    54961 aatcgttact tctacatcga tatttcctct agttgctttg gagtaagggc agaattcatg
    55021 cgcatcttct gcaatttttt gggcttcttc ttcgctgatg ccatcgatat gcacttctaa
    55081 tactacaccg atctgatagc cgccatcatc taaattataa agagagacac gtgcttttac
    55141 tgtggactct gctgtcattc ctgcttcttt gatcatatgt tgtaccgccc cattgaaaca
    55201 agaagcataa cctgctgcaa ataattgttc tggatttgtt ccttctgcat ggattcctgg
    55261 aggagtgatt ttcatatgca tcgagccatt tggtgcctcg acttctccat tgcgcccgcc
    55321 atggttgatc attgctgttt cgtatgcttt tttcattgta ctgctccttt cgattgacca
    55381 tttgctactt ggctataatt atagtgtatg acaagtaagg cgctttctac aaaaattctg
    55441 cttattcgaa taccagaatg ccgtcttcta ctatttttcc aaaaaacaaa aaaatactac
    55501 tcgtgaacaa cagcgtcata tttgttccaa aataaatagc aatcttttct acataatctt
    55561 ttatatgatt gattttaaga tacatatata ccagaaagtt gaccccataa accaatactg
    55621 ttaaaaaaat aaccatattc gttaccattt tttcctcctt ttgctggtct ccctaccagc
    55681 actcgattta accataccac tttttttgcc gtccaagcaa ctagcctttc aaaaagactg
    55741 gtttattctg ctgttaatga ttcaagatca gaaaaatgtc cgaataattt tgctaatttt
    55801 actaacgcca acttgttctt tccgaattca tcattttcta tctgtaatac tagtaacggc
    55861 tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt atggctcttc tagatcatat
    55921 cgaatacctt cttcattttc cgggtcgaag ttcatccctt tttcttcttc caacagtcgc
    55981 ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt catcgctgaa caattttaat
    56041 cggatttctt gtacttctac gggctgtttc aactctttga tttgttcatc taatgtgata
    56101 ccttttcttt ttaattctgg caaaagcatc aggatctttg cgatgacata tgcaccatca
    56161 tccagaaaat agttttcctt gaatgcagcg tgtccgcttg tttcgatggc tagctgtgta
    56221 tctttcccaa gacggttaag ttctaatgct ttattgatta catttcgata gccggaaata
    56281 taacgaactt ggatgcctcc tttttcttca atgaatcttt gtagatgaga agaagtaggg
    56341 gaattcgtca cgattcttgt tcctggatgc tcttttaata cgattgtact taatactgcg
    56401 atcaaattat ttcgattgat cactgttcca gaagcactga caactgcaga acgatccaca
    56461 tctgtatcga aaatgatccc aagatctgct tcatttgcta aaacagcctg cttgatactt
    56521 tccatcgctt ctttattatc aggatttggg atatgattag gaaatcggcc atctggttcc
    56581 aaaaattggg aacctgttga atccgcacct aagctattca atactttttc agcaaagaat
    56641 ccaccagcac catttccggc atcaacaatg attttccaac catttagtgg tttgctttct
    56701 agtgttccaa tccccttttt aatttttgtg actaaatctt gcgcataagg tgtcaaaagg
    56761 tctgcttttt ctacgcttcc agtttgttcg ctttttattt tttgctgctg tgataggata
    56821 aaagcaatat cttctttttc tgctcctcct tctgaggtaa agaattttat tccattataa
    56881 taatagggaa gatggctagc agtcagcata accgcagcat cgcacgagaa ctgttcaaat
    56941 tgagtggaca taaacatagc aggcgtagta gctaattcga aatcgatgac atgtatccct
    57001 tgttctttca gactttggat caacgcctct ttcagtgctg gtccgcttat cctactgtca
    57061 tgaccaatcc caatcgtcca ttttttattt ggatcggttg atttcttctt tttctttatc
    57121 cagtttgcta gtccccagcc gatctttttt accatgtctg tcgtcaagtt tacttcatat
    57181 ccttcaactg gtaatgcgat tcctcgaata tccgatccat tttgcagcgc tttcatatct
    57241 ttcatataaa agtcctcctc atttattccc tcattttttc cagcttttct gcaaatcgct
    57301 gtgcttcttc ttctgagcgg caaataataa tgaatgtatc tacaccggcc atcgttccga
    57361 caacttcagg gtaagccact tcatctagcc aattcgttac cacatcggca ccatttcgtt
    57421 cagtcaatac gataaccatg aactgaacag actggatacg caaaacctcg cgtctaattg
    57481 ctgtacgcaa acgttcttca tttaaagaaa cagatggctg gttaaataat gtatagcgta
    57541 ctattttgtt ttcattttga ctttttacta acttcatttc tcgaatgtct cgagaaatcg
    57601 ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc aagcagctct tcctgtgtcc
    57661 caataggttg ttctgtaatg atctggcgga tcagtgcttg tcgctgtttc tttttcatat
    57721 tagacacctc tcaatgttga ttatagcaaa agataagtaa tatttcttca tattttggta
    57781 ttttttactt ttattttttg ttttcattca ggttgctaac ctttttctat tttaacacgc
    57841 aaaatcgtct tcattttttc aggtgctgat tttcttggat cgctgatgta aatctctttg
    57901 tgttctttag aagctctttc atagccttct tttgcgatga atgcttctaa tttctcaaac
    57961 gttgctggtt cttcggcata gggcccgacg tgtaagattt gggcacaaag accttcttcc
    58021 atctttttga atactacttg ttctttcaag tcttccggaa gtttgctaga acgctgaatg
    58081 gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc ggatcatcaa ttgataagaa
    58141 aaatgttctt ttttcatcac tggttcatgc aaatactttt cttgcagtcc ccattgtcct
    58201 tccagtggat agacagtata catctgataa tcaggaatca gccaattttt tttaggcgac
    58261 atgcgtattg catagctgac tgcatataga caggctactc ttcgtttaaa gtcttcctga
    58321 ttcgggtcgc cgatccctct gatgctaaag aatgattttt taggaacctc tagtatttgc
    58381 gggctttttt tcatactata gctcttgtct ttacgccatt caattttttc catttttctt
    58441 cctccgcgaa attccattta gttatttatt atcatacctc tttttgagtg acttggctaa
    58501 tcgtgttgac actatttttc agtttgtgct agaataagtg aagtaaataa atcgtacaga
    58561 taacacgttt cggcgtgtcg agagagaggc ggtttctatt tttataatag aaatcactct
    58621 ctttttttac gaaatttttt agaggtgatg taaatgacaa aacaaaaaca gctgctttta
    58681 gtacctgcag taattgcaac agggatgatg tcttttgcgg gcgtattgat cgagacggcc
    58741 atgaatgtaa ctttcccaac tcttatcaga cagtttgatt taacgactgc acaagtccaa
    58801 tgggtaacaa cgatttatct tttgatgatt tcgatcattg ttccgctgtc tacttatttg
    58861 aatcgcaatt ttagtctcaa aaaactcttt ttagcttcaa atctgctttt cttggcaggt
    58921 ataatgatcg atttcttctc tcctaccttc atggtcctat tgtttggtcg attgctccaa
    58981 ggtgcagcga caggtatcgc tcttccgttg atgttccata ttatcttgac atttgccccc
    59041 ctcaatcgac gaggcgcgat gatgggtgtc ggtactttga caacggccat tgctccagca
    59101 attggcccca cttatggagg cattatgact tcacatttta catggaatca tatcttcctg
    59161 tttcttgtgc ccgttttgtt tctttctttg attatcggct ggtttgctat tcccgagatg
    59221 gcagtacaaa aaagtggtta tttggattgg ataagcgttt taggaatttg tcttttgttt
    59281 agtggaagtc taacattttt gagtacgttg ggaacagttt ccagctggat tgctttaatc
    59341 atcggcggta ttggctggtt ccttttttac tatcgaagta aaaaagtgga gcatccactg
    59401 atccgactgt ctattctttc aaataaaaca ttccgcttgt ttttgattgg cttcttagtt
    59461 tatcagtttt tattacttgg tgtatctttt gtcttgccga atttccttca gatcgttcaa
    59521 ggaagtagtc cttttgtcgc tggattagcg atgcttcccg gcgcagcggt tggtgctttg
    59581 ctttctcctt tttccgggaa aatgctggat caatatggtc cgaagaagcc aatttttgct
    59641 gggctgattc tttctttgat tggttggcta gcattattcc tactcatagg acacgcttca
    59701 gtgggtgtat tgattgcttg tcatgtgttt tatatgatcg gtatcggatt atcttacagc
    59761 aatatgatga ccaccggaat gaatgcactg aatgaagaac tacaaggaga cgggaacgca
    59821 atgttcaata ccttgcagca gttttctggc gctgtggcta cttcattagt agcggtcatt
    59881 atcaattacg tccagcatca tacttcccat aactatgaag tgtctactac attaggatca
    59941 aaagcagcat taggcgtctt gttgctgttg cttctcgtaa gctttgctcg attcgcctat
    60001 tatctgttct ttgctaaaaa agcgtagatt ccatatacgg caggtgttgc atctgccgtt
    60061 tttttgtgtg aaaatggttg tttgtaaaag gaggcttttt tatggaaaaa attgccatta
    60121 tcggtggcgg gatcattggt atgaccctag ccagttactt agatacatca aaattcaatg
    60181 ttgctttatt tgatgaaggg acaggacagg caactaaagc tagcgctggg attatctccc
    60241 cttggttgtc gaaacgcaga aacaaacaat ggtatcgtct ggctaaagac ggcgctgctt
    60301 ttttccctaa acttataaaa gatttccaac ttgatcaaac gatttacgca caatcaggga
    60361 cacttttgct tcgacctgaa aaagatttag ctgaattggc tgttcttgcc gagaaacgaa
    60421 aagaagaagc gccagaaatt ggaaacatcg aatggctttc acctgaacag acatctcaag
    60481 cacttccgtt attgaaacca gcagtttcac tgcgtatcag tggtggtggt cgtctggatg
    60541 gaaaagcata tttagaacat cttggtcagc gtttagcaca aaaacaaatg gagcagatcc
    60601 aggcaaaagt cactttgcat aagaagagcg attcttggct catcaaggga ccgtttggag
    60661 aatacacagc tgatcgtgta attttgacac ctggcccggc acttaagcct ttattacaag
    60721 aattaggcta tgctgcagat atacgtccgc aaaaagggca gctcttagca tttcagacat
    60781 cttataagat gagtcaagac tggcctgttg ctatgcttga cggagaagct gatttcattc
    60841 ctttcatgga tggaaagatc cttttaggtg ctacccatga aaacgatcaa ggctgggatt
    60901 tggctcctac tagcgaagct tataagggat tgactaagag tacagaacag ttcttgactg
    60961 atccagatca gataaaaaac tggccatacg agttccgtgt aggtacccgt gcttatacgt
    61021 cagatttttc cccatttttc ggcgtactgc cagatgatcc aagcttactg gctgctagcg
    61081 gtctaggctc ttctggcttg accacaggtc cttatatcgg ctatctatta gccaacttct
    61141 taaatactgg tcattggcct acggaagatt atcaaaagga catctccacc tatattacga
    61201 aaaatccatc atagaaaaac agctttttca agtaaggatc ccgagcgata ttgcgcatgg
    61261 attacttctt gaaaaagctg ttattttagt tcaatttctg aatcaaattc tccaaacttt
    61321 cttttgcttc atctggcaag agatcttttc ctatctgagc ttcaatgaat cgtaaacgaa
    61381 tatcaagtcg ttgtttcacc agatttttat aggacgtatc ctcaaaagaa acaggaaaat
    61441 ctggtatagg taaatagtgg atgtcttcaa atggaccaaa cgacttgaat tctgccgttt
    61501 gttgcacgat tctttcaacg attgacaatg tcgtttcagg tttgattttt ttatcatcga
    61561 aatatccagt attcaggaca tagcaggctg tttgctgttt caaaaacaac tctcgaaaag
    61621 cttgatagtc ttccctaaga ggatagacac ggaaaggatt agcaaatggt tcaatgacta
    61681 gctcatctag ctgtcttttt gtagtgatat tttccgcgtc tgatcgtttt gttgctaatg
    61741 ttgcaccaaa agacgctgct aaaactgggt cattgatctt gataattggc ggaagcgaat
    61801 catctttcat gatccaaaaa acagcatcga tcttttcgct aagatgatcg actcggtcgg
    61861 gtgtcgcata acgtgatttg actgtccgcc catttccgtt tcgtatatct cctgttacta
    61921 ggactttttc tcctttactt gtacatgtca cgcccacatt ctgacaagta aggaaagaag
    61981 aaatggccgg atcatcagac ggatagtctt gtgttttatc aaagtaagaa ggttccaagg
    62041 cagtagcaaa accatttttt cgagaaataa cgaaagcatc gtcatgcaag atcgaaacag
    62101 agtgaccttc cgtatgtttt gctaaggtaa tcgttgattt tccagaaccg gacaacccaa
    62161 atacagccat cgtataggtc tggtcattac tagcatattg tttcatccca ccgtggcagg
    62221 caataaagcc attgcgattt cccaatgccc aagcaagcgt caaagtcgct ttttttaatt
    62281 ctccaaagta acgtaatcct agcacagccg ctgtattatg gagagcatca aacaaaatga
    62341 gtccatttgg aaatgtttca tgtgtccatt cgggatcaca aaagatataa agatctccct
    62401 catcaaagga aacagacttt tgataagtct ctaagatctt cgaattcgct ggctgaaaat
    62461 tcagcaaata agaatacaaa ttgttctcaa atccttctgg aatcagcaaa tgactttgca
    62521 cagaaaattc ttcagatagg ccaacgatta cttttgtatg gtaaaactgg cgcttgcgac
    62581 tttgatacac agcttctctt aaaattttct cgtatttgct ttgttccttg tctaagtcct
    62641 caaagatccg ccgagcactt gctgttcttc ccacaatgct tccatcattg aatactagtg
    62701 tcctaacatc agctggtaaa tctagttctt cagcatgtga gattgttaaa tctgtgatga
    62761 tcgttcctgg actccctttt gctagttgat aagctgtctt cctatcaaaa acttcatgaa
    62821 cattattacc gtaaaatgtc gtttctacaa tcgatcgaat actggataac agtggatttc
    62881 cacttgtgat ttcgtttaat tcgagactct cttttgtact catggctcct cctcattccc
    62941 taaacaaaaa aacgttttct ttattataca ttattcgagt ttttatttgt actgctgcgc
    63001 tgtgggaagc aaacgagtta tttttcacac aaaaaaaccg agaacttgaa taaacaagtt
    63061 tctcggtttc atcattttcc ttttatcggc ttagtaccag ccgtttgcta accagaatgt
    63121 tttagcagca tcccatgaac cataacgaga tgttacatat tgttctgcta cacgttcttg
    63181 attggcagct gaatagtcgc cgtttaagta tgaagcatct aattgataac ggccgatgta
    63241 acgtccgtta gtagctgtgt atgaaccgcc tgattctttt tgtgcgatcc attcttttgc
    63301 agagcttgaa gttggcgctg ttgcagcagc tggggcagca ggagctactt caactgtttc
    63361 aacaggtgca acgtatgtat gttcttgcgt tgctgtttca gttgtagatg ctgtattttc
    63421 tgttgttttg ttttctgttg ttgctgaaga atcatttgaa gttgggattg ttaattgttc
    63481 accaacataa atgcggttga tgtttgcgat cgaatttttt tcagcaattg catcgatcat
    63541 tgagttgtct cctgcaaatt tttgtgagat cttagataat gaatcacctg attttactgt
    63601 ataaacttca tcagcgtgag catttgtagt tcctacaaac attgcagtag caccagcagc
    63661 aaaagttgta cctaaaacaa ttttcttaaa tgaattcata ttaaactcct ttttttctcc
    63721 gttttttatt ctttcgacgc tattaacttt atcatttaga aatatttcat aggtaaaaga
    63781 aacatgacat ttaatgacaa aataacgaat tatttaatat ttgtaacatt taaacaaata
    63841 tttttttgat acaaaaccat aaaagccttg ttgtataagc aaagtaatcg tttttctatg
    63901 tttttttatt tttgaatgaa aaacgcagat tctgtaacat tcactgcaat aatccataaa
    63961 aaaaagcaaa aaaatttttg atttttatca aattctctta aaaaaatgta aaaaatacaa
    64021 aaaaaccagt aattgttaca acaattactg gacaaaaact ttgaataatg ttaactattt
    64081 ttttatttta actttctccg caataatttc tgggcatgtt ccaattcgtt tataacgact
    64141 tcttctgttt ctttagctaa tatttcatct aatacatcaa gccatttttc cggttctttt
    64201 gttcctagac gtccaatagc ccaagctgct gttcctctga tgacagggcg gacatctgtt
    64261 aaacattctg aaatctcagg caatgccgtt cgatcaccta gattagctaa agcaatcaat
    64321 gcgtttctct gcaaaggttt cttcccacgc catgaaccag ctaaatgccc aaattgctgt
    64381 ttgaagtctt tattagacat cgaaagcatt ggctttaatt ttggatatat ttcgtctact
    64441 tttggttcca tctcttcatg aaaatgaaaa tcttttcctt gattgtaagg gcagactaac
    64501 tggcagatat cacatccata aatgacattt cgcatttttt tacgatattc ttccggcatc
    64561 atcccttttg tctgagtttg ataagacaaa catcgctggg cattcattct tccgtcacca
    64621 agcaatgctt ttgtcggaca agcagtcacg cagcgcatac agtcaccgca accaaattct
    64681 cctggtttat caggctcaaa tacaatatta gtaacgatct caccaagata gacaaatgaa
    64741 ccgaactctt cagtgatcaa caatccgttt cgtccaataa atcctaaacc agctcgctgt
    64801 gctacagcga catcgatcag ttctccagta tctacttgcg gagctagacg ccattcctct
    64861 tctttttgcc atttttctgc tcttgtttgg atgaattcga tcaatcggtt caaacggtct
    64921 ctgagtatat catggtaatc gatcccccaa gaagcacgag caaactgccc gcgtttttca
    64981 tccctaggca cttcttcatg gatcctagta ggatacgcaa gtgcaatgga aatgatcgat
    65041 ttcggctgat caaatgtcat ttctggataa agacgctcat cgatatttgg atgttcaaag
    65101 ccagaagtat ggccagctgc tttttgttct tccaacgatt cttttaatga atcaaaaggt
    65161 tccgccgtgg tgaacccgat tttgtcaatt cctaatcgtt tgctttcttg tatgatttct
    65221 tcttttaatg tcatggtctt cctcgcttgc tgttaacggc tgtataaccc ataatatagt
    65281 ttttcttttt tcagctggac aaactggatc tgctgatcgg caatcttctt ttcttccatc
    65341 catttttttc ttgcagcaaa tacttcccaa taatttgttg aaattaattt tcttttgtta
    65401 tctaatgcat taaaaaaatt caatgaaact ggttttgtac ttaacagttc atggagcctt
    65461 acctcttccc atggcgaaaa ctcagacaga tcgcgggaat acaatacttc ttcatagaga
    65521 tttttttgct gtgtgtacgt gaatgtttgc gggattttcc caggcctagc aatttctact
    65581 agacgattat aaaacatatt cattaatttg ctgttggcaa taaattgact tttataatag
    65641 gccgactgga tctttttgat tactccttct gctttgatga ctgaaaataa tgcaggccat
    65701 gctttgacgg ttatttcgtc gttttgttta actaatacgc caggtgtgaa gccgactgga
    65761 gaaaggaaca caaaataacc gataccggta ttttcatcta aaggctgaaa ttcatcaaac
    65821 aaccatttgc ctatgtacag ctcttcatct ggttctgttg tctcattttg atttgctatg
    65881 aataatttag ctaattctgc ttcaagaaat tgaaggtctt gatccttgtc ggtattttcc
    65941 tgctggctga tcaatcgaaa gacttcttct ttaatcgtat atttatcttt acgtgtaaaa
    66001 ttcatagcca caccttcctt ccttactcta actataacgg aatttcttca aaaaaggtat
    66061 ctgtacgacg aaaaacagca taattttttt tcatatctct tataaaaaat gcaaggtctg
    66121 ctcctcaagc tagaccttgc acttttcagc tttcttttgt ttgtgacaaa ccttcatgga
    66181 tcgtttcaat attccatttc atcatctgat agtaagaatc tccttgttct ccttcttttg
    66241 ctatggaatc agtgaacagt ttatcataga ttttcaaacc cgtttctttt gctacccgtt
    66301 ccatgcttct tgagtctaca ctggtttcca cgaataaaac cggtacttct tttgctctta
    66361 tctgatcaat gatcgctttc atttgatcag gcgtaccttg actttctgta ttgatctccc
    66421 atatataagc tgctggcaaa tcatatgctc gtgaaaaata cttgaatgcc ccttcacttg
    66481 ttactaataa ttttttgttc tcttcgatag aagcaaaact ttccttcgct tgtgtatcta
    66541 attcttttag tttttccaca tatgcttctg catttttttt atagagtgtc gcattttctg
    66601 catctttttc agagaatata cgtgcgattt cctccacata ttttattccg ttagataggt
    66661 ctagccaagc atggggatct gcttttgtat gttcttcacc gctagttaaa taaagaggtt
    66721 ctacattttt gctaactgca aaataatctt ttccttcttc ttttttagcc gtttccatca
    66781 agttatcgaa ccagctgtta cctgtttcaa gattcaaacc gttgtataaa ataacatctg
    66841 catcgcttgc ctttttgatg tcttctggta gtacttcata ttcatgcgga tctgttccga
    66901 ctggtacgat actgtggata tctatttgat ctgttccgac ctcttttgcc atgtccgcca
    66961 agatcgaatt ggtagccacg actgacaact tttctttact tccttcatcc gcttggtcag
    67021 aagcctgctt tccgcaaccg gctaatacca agaaactaac tgccaagatt aaaaagagtg
    67081 atttttttgt tttcatctat ctgcttcctt tctgaaataa aattcctttt gttggagaaa
    67141 ataaaaaagc aaggataaaa aatgcggtac atgctaacac gatcgtagct cctgatggcc
    67201 aattgtaact ataactgaaa aacacaccga caactgcact tagcataccg attcctgcag
    67261 ctgtaatgat cattttcagt aaatggttcg ttagcaagta agccgtggcg gctggtgtga
    67321 tcaacatggc aatcaccaag attgttccta ctgtctgtaa actgactaca gccactaatg
    67381 tcaaaaagaa catcaaaaga taatggatca gcgatgtgtt cagcccataa gcttttgcca
    67441 ttgtcggatc gaatgatgtg atcttcaatt ctttataaaa gaaaaagaca aatatcaaga
    67501 cgattccact aacgagtgct gtcagcaaca aatcgctttc cctaacagct aagacattcc
    67561 caaataaaat atgatacaaa tctgtcgcac tctgggcata tgaaatcaag ataatcccta
    67621 atgcaaaaaa ggagctaaag acaattccaa tcgctgtatc atttttcaat cggctccgct
    67681 gagtcacgaa accaatcact gctgctgtta gcatcccaaa agcagtggct ccaaagatgt
    67741 aactaaaacc aaacatataa gaaatggcta cacctggaag aactgcgtga gagatagcgt
    67801 ctcccatcaa agacatccct cgtaaaataa taaaagaacc gatgactcca gaagcaagtc
    67861 ctacaagcat ggaagtgacc aaagcgtatt gcaggaattg ataattcatt aatccatcaa
    67921 taaaggattg gatcattttt tctctcctcc ttttactaaa tgtctgatga tctcaccata
    67981 ggccaattga aggttcttcg atgtaaagac ttcttgtact ggaccggaag cgatcagctg
    68041 tttatttaaa agaataacct catcgaaata ttcttctact ttatgaagat catgatggac
    68101 gatcaaaatc gtttttcctg aattcttcaa ttcctgcaag atgtcaaaga tctttcgttc
    68161 acttaacgca tcaatcccta cgaatggttc atctaaaaag atccattctg ctccttgggc
    68221 tagagctctt gcaataaaaa ctctctgaag ctgtccaccc gatagttcgc tgatctgtct
    68281 tttggcatat tcttccatcc ctactttttt caaagcttgt cttgcacgtt ctttttcttt
    68341 tttcccaggt ctttgtccaa ttcgtaaaga tggatatgtt cctaaaagta caacgcctaa
    68401 tacatcaatt ggaaaggaaa gatccaattc acttcgctgt tccacgtagg ctattttttt
    68461 acggactgag tttaccgact gtccagaaaa ggtgacttta ccagtagtag ctggtatcaa
    68521 ctctagcaaa gatttcataa atgttgattt tcctgcaccg tttggtccga taataccggt
    68581 aattttttgt ggatttatcg tcaagttgat agttttcaaa acagttttcc cttgataagc
    68641 ggctgaaagg tcttgaatta caatggccgt acgttccaaa tcttacactc ctttttaggt
    68701 ttacctaact ttttatttaa atatagttta actaaaatgg aaagcatttt caagtagaat
    68761 gatgaaaaag tttttttcga attttcctcg cattttatga aaattttctg tagaatcaca
    68821 tcaagagttc aataaggcta acctaataat gaaaaacatg tgttgaaacg tttgattatt
    68881 ttttcttgtt gactcaacaa cgaaaggagt ttttgtatgg aagaagaaaa gttaactcga
    68941 agtcttagtg cccgtcatat ccaaatgatc gcactaggtg gaacgatcgg tgtcggtctg
    69001 tttatgggtg cctcctcaac catacgttgg acagggccct cagtgatggg agcctatgcg
    69061 attgcaggat tctttttgta tttgattatg cgtgctttag gcgaaatgct ttacgttgat
    69121 ccttcgactg gttcttttgc aaattacgcg agcgagtaca tccatcctgt ggctggctac
    69181 ttgaccgctt ggagtaatat ttttcaatat attgtcgtag gaataagtga agtgattgct
    69241 gtaggatctt atatgaatta ttggtggcct gatttgccgg caattattcc cggaatcatt
    69301 gtcgtcttgt ttcttatgct ggcaaatctt atttctgtca aggcgtttgg cgaattagaa
    69361 ttttggtttt cgatcatcaa agtcataacg atcattttga tgatcattgc aggtcttggg
    69421 gtaatcttat ttggatttgg taatcatggt caggcagtag ggatttcaaa tctttggaaa
    69481 aatggtggat tcttcactgg aggcgtcaaa ggatttttct ttgcattatc gatcgttgtt
    69541 gcttcctatc aaggaatcga actgatcgga atgactgctg gtgaagcaga gaatcctaaa
    69601 aagacgatca ttgaagctgt ccagtccact atcggtcgaa tcttgatttt ttatattggt
    69661 gctattttta tcattgtgag tatctatccg tggaatcaat tgagtgagat tggttcacct
    69721 tttgtacaaa ctttttctaa agtcggcatt acatttgctg caggactgat taattttgtc
    69781 gtgattacag cggcattatc aggttgcaat tcagggattt tcagcgcaag tcgtatggtc
    69841 tatacacttg ccataaatgg aaagatgtct aaaaaatttc tgaaactatc tcgtcacggt
    69901 gcgccttttt atcctgtcgt agcaatctca ggtggaatct taattggtct gatcttaaat
    69961 tatcttctac caatgttcat caaccagtca gaaaatattt tcgttttcgt atacagctca
    70021 agtattttgc ctggtatggt tccttgggta gtgattttga tcagcgagat tcgcttcaaa
    70081 aagaagcacg cagataaaat gcatgatcat ccttttaaaa tgccactatc tccttatacg
    70141 aattatgtga cacttgcttt tttagctatc gtattgattt tcatgtttat caatcctgaa
    70201 acgagaatct cattgattat tggactcgtt ttcttgcttt acatgacgat ccattacttt
    70261 gtacgcgaaa aaagaaccgg aaaataaaaa aagaacgaag cttcacctta gtggaagctt
    70321 cgttcttttt tattgctttt atcaattcaa ttttagcgtc tcaccgggag tcaggaaata
    70381 attctccatg ctcatcccat tcagcgacaa gatcgtttct actggtacgc cagttcgttc
    70441 ggctatttga tttggacctt ctccttccaa aactacggtt gtcgcagcct gtgaagtcgc
    70501 gctgttggta ttagtttcag aggaatctgt tgtgtcttgt gttgttcgag cttgcatttc
    70561 agaagcttct accgactctg ctgtctcaga atcagaagat gttgtgtctt gtgtgcttgt
    70621 tgactctgct tgaagagagg cgctagtctg caaataaata tcggaaatct tagcgacatg
    70681 attcgtataa ttagccgata attgattgat caaagtatct aagtctacac cgtctttatt
    70741 ttctgctgcc tgatacgctg cacgtaattt tctgatccct tcgtcggaga ttgcttgaag
    70801 ctcacgtgct ttttggttag caactgctga taaaccagct attccctctt gatttccctg
    70861 aatttctgtc tggtattctt caatcaatgc aggcgtcttt tcttcgatct ttttcgaata
    70921 atcatttacg attgcttgaa gttgctctgg caaaccattt gctgtttttt cttcagaagt
    70981 ttgtgtctct tttgttttag ttgatgactc acttgtttgt ttcgtctctg ttttctttgt
    71041 cgttgtttcc gttatggtcg tacttttcgc ttctgacgaa ttttttccat gaaaatatag
    71101 acccgcaact cctcctgcta tgatcaaaaa cacggcaact gctgccccaa tcatgatcat
    71161 ccgcttacga gctgcctgtt tttgctgtct tcttcgggtc atccgaacat tttctcccca
    71221 ctcattttca tcatacattt ttttcaccac caatttttat gtataatagc gttatcaaac
    71281 gcttcatatt cttattgtag caaataattg tcgctgtgca catttttatc tttgttattt
    71341 ataagaaaat ttcaccagtt gagatgattc caagattgtc cgtcgatttc tccttgcagc
    71401 tgcattgttc gttcgtctat ctcagccatc agtttcttta tttcatataa gagcgcacgg
    71461 tcttgatatt ctgatttttc gcttaattca tctaattgtt ggatcagcca atcatttgtc
    71521 ataatgaagt tcctttcatt tcttgcagtg taaaggtcaa gtcttcgatc tgctcttttg
    71581 cctcagtcag tgcttctacg atatatgctt gtttttcaga ttcttcttcc tgcattttct
    71641 gattttcctg tactctttga ataaaccagt caatccgctg agtcagcgat ggtttgcctt
    71701 ccaatgagag atactgctga taagcaatta gcttctccca acgtttttcc tgggataaat
    71761 acataaattg tgctaaaacg aatggcggaa gataggtcat atggaattta tttgcgattc
    71821 gctgatacgg cctcaaaaat tcggaaatcg tatattcttc ttttcctcca gcttggtatt
    71881 ctttttccgc cacacctgtt gtcaatacga ttcctagttc tttccctttt aatacatgtg
    71941 ctgctcgttc caagacatta tcttgccaaa tttttaaatg agcaggagaa ctataccagt
    72001 aaaacggaaa ctggaaaatg atccgatcat gctgggccaa gagctgtagt tcagtctcta
    72061 tatctatttt tccgtctgga taacttgatt ccaaatgatg ccaagtagct ggtaaaccag
    72121 cagaagcttc tttgaaaaat tgctgattta aagattcttc gatcgttgga tggctaatga
    72181 tgataagtgt acgcatccct tttcctcctt tttagtcttc gctttacagt gtagcataac
    72241 cgccacaagt ttcttttgcc gatgcttgtc attttaacca gactaatcag gttgtccaag
    72301 aaactgcggt ttgtttttcc aactgttttt tcaaggtatc caaagcaata ttcttaaaat
    72361 tttcgttttt catacgttta cgatagttcg tagccgtttc tccggtactc tttttgaaca
    72421 ttcggctaaa tacgactaga ctattgaacc ctacttgata ggcaatactt tccacggatt
    72481 catccgtcag agaaagaaga aacgcccctc gattgatccg taccccgatc aaatattcct
    72541 tgatactggt acccatatga tttttgaata ctcgcgacaa atggctccga ttgaccgcta
    72601 aatgctgggc gatttcctca acagacaatt tttcagcata atgtgcctcg atgtatttga
    72661 ctgtttcaac agctaaagag gaatgaacct tttgtacacc accgctgacc tttccgccat
    72721 cttttaaaag gactgataaa aaacggtagg ttaatgctgt taactgtaat tcattttcca
    72781 aggtttcttc cgtatctttc atgcattcta aaataatgtc gatatatttt tgtatgtcag
    72841 aagagaccat cgtgtattgg tcttctctga aaagcgactg ccgaatgatt tcttctgcag
    72901 cactcccacc aaatgaaagc cagcaataca tccacggatc ttctccatct gataagtaaa
    72961 acgtcgagtc tcctggacga atcaagaaca gatcaccttt tttcaattgg aattgttgat
    73021 ttttcacatg ataagatcct ttgccttcca tcacgacatg caggatgtaa tcattgcgaa
    73081 tagcaggacc aaaagaatga aacggcatcg ttttagagaa accacaaaaa tcaaaataca
    73141 attctttttc tacttgttga tgttcctttt ttaaaaaaat cgattgctcc acgtctatcc
    73201 ctccttactc ctttagtata atgcaacaaa aagttaaata aaagtcacag aaatatatta
    73261 aaaaggaagc gatttcttgt taagtttaag tcattaaaag atctttgtta ttcgttgtaa
    73321 ccggtttact tagtattata tattgaacag gagaggaata cagattatga aaagcaaaat
    73381 gatccaacgt gtgtcctacg ctttaggcgc ttttggacac gacacattct atgttacatt
    73441 aagcacttat tttatggtat tcgtgacaag ccagatgttc gcaggaacag ataaggcaac
    73501 gaatgcaaaa atgattgcta cagttacaag cttagttgta ggtatccgct tagttgaaat
    73561 tatttttgat cctttgattg gtggcatcat cgataatact cgtacaaaat acggtaaatt
    73621 caaaccatgg ttagttatcg gcggcgttgt tagttccgta ctcttggtag caatctttac
    73681 caatttcttt ggcttagcta ctcataatac gactttattt atcatattat ttgcaatcgt
    73741 tttcatctta ttggatagtt tttattcatt taaggatatc gctttttggt caatgattcc
    73801 agctttgagt acggaaacaa aggaacgtga aaaatttgct acgtttgctc gtttcggctc
    73861 ttctctaggt gcaaatggta ctactctagt cgttgtccct atcgttactt tctttaccta
    73921 tcttgttact cataaacata ttgaaggcgc ttcaggctgg ttctggttcg gtgtgattgc
    73981 tgctgttatt tcaggcggta ctgcgattat cactgccttg ggcacaaaag aagtcgatac
    74041 tgcgatccgt cagcaaaatg aaaaagctgg gatcaaagat gtgttcaaag cagttgctca
    74101 aaatgatcag ttgatgtggc ttgcccttgc ttatatcgct tatgcgattg ccaatgcagc
    74161 aacaactgcc gtattattct acttcttcaa atatgtactt ggccaaccaa ctgaattttg
    74221 gatcgttggt ctagttgctg ccttacttgg tttagtagct gttccactat tcccaatgct
    74281 tacacgcgtc atctctcgtc gctacgttta ccttggaggg atcgcaatga tgatttcttc
    74341 ttactttttc tttacgatcg caggttcaag tttgccaatc gttatcatcg ggctagtatt
    74401 gttctacttc cctcaacaat tgattttctt atccgctttg atgacgatca cagactctgt
    74461 tgaatatggt caatggaaaa atggtatccg taacgaagct gttactctat caattcgccc
    74521 tttactagat aaaatcgctg gtgctttgtc taacgggatc gtagggtttg tcgctatcgc
    74581 ttctgggatg actggtaatg ctactgctgc tgatatcact gctcatggcg taacgacttt
    74641 caaagcttat gcattctatg ctcctgctgc tttgatgatt ttctccgcta ttatttttgc
    74701 ttggaagatt acattgacag agaaaaaaca tgcacaaatc gttgagaaat tggaaaacaa
    74761 attggctcca gctgatacaa tggaagatta acttcacgat gcagtagttc cttcccatta
    74821 agaaaggatc ttgaaaatga agattacaga aaaagatttt ggccaaggtt atcacttgat
    74881 aaccttggag aacaaaaaca agctagcact ttctatctct gatttaggtg ctagaatcgt
    74941 cagtttaaaa tcaaatgatc gagaattagt tttgggattt gacaccgctg aagaatatat
    75001 cgaaaaagat ccgtatatcg gtgcttctat cggtcgcacc gcagggagaa tcgaaaatgg
    75061 ccgcttttct ctcaatggaa aaacttacca attagccaca gatccaaaaa ctggacataa
    75121 tctgcatggt ggtgctcctg gatttgaatt aaaaaaatgg tcttatgtca ttttgaatgg
    75181 cgaaaatgaa gcttctgtca tttttactac tacaagtccc gacggagaac atggttttcc
    75241 aggtacaatg gatgtggaaa tccgctatac tttgacaaaa gataatatct ggcgagtgac
    75301 ctctcgcggc accagtgacc aagatacttt attcaatccg acaaatcatg tttacttcaa
    75361 cttgacggga gatgcttctc agtcaatcga tcaacatgag ctttggctca atagcgaagc
    75421 ttatgctcct ttgcgaacag atagtattcc tataggggta aaagaaaatg ctgcaggaag
    75481 tgctttcgat tttcaaatac ctaaaaaatt agcgtccgtt tttgctagtg atttggatca
    75541 aaaaaatctt gttgacggaa tcgatcatcc atttttctta aaagaaaccg gcttgggtaa
    75601 agaagccgct cgcttgacta gccccgataa aagaatccaa gtagatattg ctacagatgc
    75661 ttctagtgtg gttattttca ctgcaaattt cggcacagaa acaccagaaa tgcgcaaccg
    75721 aaaactggca catcacggtg gcatcacatt tgagactcaa acagctccag gtgcagagcg
    75781 cttctcagca tttggttcga ttcatttaaa agccggatca gtatttgaaa cagtaacaga
    75841 attcaaaatc aaaacaagaa aggaataact catcatggaa atcaaaagaa gcttaaacac
    75901 aaaatttgcc gaaacattcg gacctaaaaa aactacacaa tacttctcac caggacgcat
    75961 caatttgatt ggtgaacaca cagattacaa tggaggccat gtcttccccg cttccatcac
    76021 ttatggaacg caaggtgtag cagcacctcg agacgataat aaaatattag tttattccac
    76081 aaactttgac gatatcggtg tcattagttt tactttagat gagctagaat atgataaaaa
    76141 agcaaactgg gcaaattacg taaaaggaat ggtccttaaa ttaaaagaag ctggacactc
    76201 aatcgatcat gggtttgagt tattagtgga aggaacaatc cctaatggtg caggactttc
    76261 cagtagcgct tcattagaat tattagtagg tgttgtatta gaagatctgt ttgatttaaa
    76321 aacagatcgc ttggaactag tccaaacagg taaaaaagta gaaaatgaat tcatcggtgt
    76381 caattcaggt atcatggatc agtttgccat cggcttcggt gagctagatc atgcaatctt
    76441 attagataca aatacgctga aatacgaaat ggttccagtg aaactagatg gttatgcaat
    76501 cgtcatcatg aatacgaata agcggcggga attggcagat tcaaaataca atgaacgccg
    76561 tagcgaatgc gaagaagcct tggcacgttt gcaaaaaact ttgcctatct cttctttagg
    76621 agacttagat gaagaagaat ttgaatcaac tattgaccaa atcggcgatg atacattgat
    76681 acgcagagct cgccatgccg tttctgaaaa tcagcggact ttgaaggcaa aagctgaatt
    76741 agaagctggg aacttagaag catttggtca actgttaaat gattctcacc actctcttcg
    76801 ctatgattat gaagtaactg ggatcgaatt agatacacta gtagatgctg ctcaaaaaca
    76861 agaaggtgtc ttaggtgcac gaatgacagg agctggattt ggtggctgtg cgattgctct
    76921 tgtcaaagaa gaaaatatac ctgccttcaa aaacaatgtc tatgatgaat acatgaaagt
    76981 tgtcggctat gctccggaat tttatgttgc acacattgga aatgggacaa caaagatcga
    77041 tccagaagct gttcatgttt gataaaaaaa tcaacgatct cagctaaaaa caaatagata
    77101 aaaataacct ctcagcaatt tccaaatgtg agccttttgc tcgtatttga aaattgctgt
    77161 tttttattga cacggaaaga gaacgtgtgt tctaattgtg ttgaagaggt gattgttatg
    77221 tgggcgaatc aaaatccggt atttgtttat gaaaaagaac cttcaagaga tattttatgt
    77281 attgactgca aatcttttta cgcctccgta gagtgcgttg aaaaggatct tgatcccctt
    77341 acaactaaat tagtagtcat gtcctatccg tccgattcga cagaaacacg gggtagcgga
    77401 ttaatcttgg cttccagtcc tgcagcaaaa aaagcttacg gcatcaccaa tatcagccgt
    77461 gccagagatc ttcccttccc ctatccaagt gatttatata ttgttgcccc aaggatggcc
    77521 tattatatgg aaaagaacag agaaatcaat tctatctata aaaaatatgc agacgaagcg
    77581 aaccatcatg tctattccgt cgatgaaagc ttccttgatg taacaaatag catggcactc
    77641 tttggtaaaa caaatgcgta cgacatggct aaactgatcc ataaagatgt gtttgagcag
    77701 accggaatct acacgactat aggaattggc gataacccgc tacttgctaa actagcctta
    77761 gacaatggct caaaagacgg aaagcaaatg tttgctgaat ggcgttatga agatgtacca
    77821 gaaaagttat ggaaaatctc agatatcact gacttttggg gaatcggcaa acgaacagca
    77881 aaacgtctga aacaaatggg tatacattct gtttatgatt tagctcacgc ggattattat
    77941 cacttgaaaa gcaagctagg ggtcatcggt actcagcttt atgcccatgc ttggggcatc
    78001 gatcgaagtt ttttgggaca agaatataca ccaaaatcaa aaagtatcgg aaatagtcaa
    78061 atcctagata gagattatac aagacgagaa gaaatcgaga tcgttatcaa agaaatggcc
    78121 gaccaagtcg gcactcgctt gagacgatct gcagcaaaaa cacaagtagt cagcttatgg
    78181 gtaggatact ctttaggcta tcttgatcca aatggcaaga ccgggtttca ccagcaaatg
    78241 aaaatcgaag cgacaaatgc tagcagagat cttgcagatg ctttattgac cattttccac
    78301 cagcattacc actaccagga tattcggcgt gtaggcgtga actgttccga cctcgtatac
    78361 gcgacaggtt tacagcttaa cctttttgaa gatcctgaaa agcagataaa tgaagcgaaa
    78421 gttgattttg ttgtcgatac gattagaaaa aaatacggct ttcaatcaat catccatgcg
    78481 catagtctct tgcaaggagg acgcgccatc gcacgtagtt ctctcgttgg cgggcatgca
    78541 ggtggtatga gtggattaga aggtggaaaa gatgagacgg acagcaaaaa aattcattga
    78601 ctataacgag tatcgagatc ggccatttgg attaaaatgg gggactgctt ttgcgatgga
    78661 agaactagtc aacggtatca aaaaaatgaa gaagaagcac gcaaacagcc tcttcctaaa
    78721 caacaaatga cattgcaaga aatcgatagt atactgacag aagccttttt atctcgtaaa
    78781 gcagtaatca ttcagctcaa tttaaaagat gaatttggaa gactcttgga tgaggtcgaa
    78841 gggcacttca ttggtgaagc ctatgaagat tactttatga ttgaccatca gccgatattg
    78901 tgggaagacg tacggtatat tgagttaaag gaaacaaaaa aatggtttgt gacatgagag
    78961 gttgtgacag aagtgatcaa cttcaaaaaa taagaaagga tttttcgaaa attgcttctt
    79021 aaatttttgt ggaattttgg cttatttttc gaagaagcaa cttctggaac aacgtatatt
    79081 agatatcaga ggttgtgaaa aagtcgctta gttttgagta acaagccaag gcgctgattt
    79141 cacaacctct gtctatctat ccatctattc ggtaagattc atgcatgacg tcttctttat
    79201 ttagtatgta gagccctttt tcttctgacc attcaacata aatcagctgt tttacatctg
    79261 catagccttc tttcttcaag ttctccataa gccatgcttc agtcaattga ttggactgaa
    79321 gcactttatg ctgaatttgc ccttcatcta caagcaggat cgataaagct ttgtcttcat
    79381 ctgatttttt caatacactc atttgaccgg cattctctag gataacatgt ttggcatttt
    79441 caagaaaaaa gcattcttgc tgtcttaaga ttgctcgcaa ctgctccatc tcgatatggt
    79501 tatttgtcaa ctctgtcatg ttgatgacgc cgtctttgat tagaacagat ggctcgcctt
    79561 tgacccaacg attgaccttt tcattttttt ggacgatacg ttcgatacca taaatcatta
    79621 ctgcccaaag cgcaatggca aataggacat gccctacatg gacattgtca tcataggttg
    79681 attcttctaa gatcccacct aaaacaagcg tatagactaa atcaaacggt gtgatttctg
    79741 acatggattt cttcccaagc aaacgtacca ctaataataa accgatcaac ccgaacacca
    79801 gtttcattgt aattgaaaaa atcatttttt ctccccctaa ctatctgtta attaaattat
    79861 atatgctttc tcacgaacac gcatggaata tacaaggaag aaatgtatcc ttttactaaa
    79921 aaaaggactg tgacactgta gtgaccccca aaagttagac ttttttggag tggagaaatc
    79981 cactcctttt ttttatgctc taaaatgata tttttacaca accgttacgg ttgttttacg
    80041 aaattggacg
//
LOCUS       DBBGRF010000004        74853 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000004 DBBGRF010000000
VERSION     DBBGRF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 74853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.004"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..143
                     /locus_tag="ACIZD4_000284"
     CDS             <1..143
                     /locus_tag="ACIZD4_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HGC5989250.1"
                     /translation="ELTDESQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQ
                     YV"
     gene            270..854
                     /locus_tag="ACIZD4_000285"
     CDS             270..854
                     /locus_tag="ACIZD4_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HGC5989251.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            965..2104
                     /locus_tag="ACIZD4_000286"
     CDS             965..2104
                     /locus_tag="ACIZD4_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5989252.1"
                     /translation="MWVEQTKDGQFKFIERYVDPYTEKTRKKSTTLTSNSPQAWKKAQ
                     KILDKKIKEALENYNKSDITFGELYKEWYEYYKQHVKRTSYLKVPMMMKHVSKHISDD
                     TIVRNIDETLINKMIEDMYTFGDLSLNYTKQTKTTLSVMLNYAIDRKYIQRNPALAVK
                     IHPKKVEEEKRKLSMDKKYLEKEEIDQILKQLYSNPRRKLHGIIAEFLYLTGLRYGEL
                     LALQMKDYEDGKISINGTLDYTSVKMDNAIKTTPKNTYSQREVQLPNRAKELIESVIA
                     DNILAGRPTDPDQYIFISTSGTPLTLHSFNAILHKVEEELELEKSLSSHIFRHSHVSL
                     LSELGVPLKAIMERVGHSDANTTLSIYNHVTKRAKQQVIDKLNSL"
     gene            complement(2193..3818)
                     /gene="groL"
                     /locus_tag="ACIZD4_000287"
     CDS             complement(2193..3818)
                     /gene="groL"
                     /locus_tag="ACIZD4_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGC5989253.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(3869..4153)
                     /gene="groES"
                     /locus_tag="ACIZD4_000288"
     CDS             complement(3869..4153)
                     /gene="groES"
                     /locus_tag="ACIZD4_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGC5989254.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            4378..5040
                     /locus_tag="ACIZD4_000289"
     CDS             4378..5040
                     /locus_tag="ACIZD4_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGC5989255.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(5116..6408)
                     /locus_tag="ACIZD4_000290"
     CDS             complement(5116..6408)
                     /locus_tag="ACIZD4_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC5989256.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            6578..7207
                     /locus_tag="ACIZD4_000291"
     CDS             6578..7207
                     /locus_tag="ACIZD4_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC5989257.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(7310..8119)
                     /locus_tag="ACIZD4_000292"
     CDS             complement(7310..8119)
                     /locus_tag="ACIZD4_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC5989258.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(8174..9043)
                     /locus_tag="ACIZD4_000293"
     CDS             complement(8174..9043)
                     /locus_tag="ACIZD4_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HGC5989259.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(9044..10360)
                     /gene="yycH"
                     /locus_tag="ACIZD4_000294"
     CDS             complement(9044..10360)
                     /gene="yycH"
                     /locus_tag="ACIZD4_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HGC5989260.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(10357..12192)
                     /gene="walK"
                     /locus_tag="ACIZD4_000295"
     CDS             complement(10357..12192)
                     /gene="walK"
                     /locus_tag="ACIZD4_000295"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HGC5989261.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(12197..12901)
                     /gene="yycF"
                     /locus_tag="ACIZD4_000296"
     CDS             complement(12197..12901)
                     /gene="yycF"
                     /locus_tag="ACIZD4_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGC5989262.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(13091..13951)
                     /locus_tag="ACIZD4_000297"
     CDS             complement(13091..13951)
                     /locus_tag="ACIZD4_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC5989263.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(13938..14507)
                     /locus_tag="ACIZD4_000298"
     CDS             complement(13938..14507)
                     /locus_tag="ACIZD4_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGC5989264.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            14888..14960
                     /locus_tag="ACIZD4_000299"
     tRNA            14888..14960
                     /locus_tag="ACIZD4_000299"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14921..14923,aa:Lys,seq:ctt)
     gene            complement(15456..15842)
                     /locus_tag="ACIZD4_000300"
     CDS             complement(15456..15842)
                     /locus_tag="ACIZD4_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HGC5989265.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(15839..16360)
                     /locus_tag="ACIZD4_000301"
     CDS             complement(15839..16360)
                     /locus_tag="ACIZD4_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HGC5989266.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(16362..17396)
                     /gene="sppA"
                     /locus_tag="ACIZD4_000302"
     CDS             complement(16362..17396)
                     /gene="sppA"
                     /locus_tag="ACIZD4_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HGC5989267.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(17429..18844)
                     /locus_tag="ACIZD4_000303"
     CDS             complement(17429..18844)
                     /locus_tag="ACIZD4_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HGC5989268.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(18813..20966)
                     /locus_tag="ACIZD4_000304"
     CDS             complement(18813..20966)
                     /locus_tag="ACIZD4_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGC5989269.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            21224..21460
                     /locus_tag="ACIZD4_000305"
     CDS             21224..21460
                     /locus_tag="ACIZD4_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HGC5989270.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            21479..21694
                     /locus_tag="ACIZD4_000306"
     CDS             21479..21694
                     /locus_tag="ACIZD4_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HGC5989271.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(22397..23149)
                     /locus_tag="ACIZD4_000307"
     CDS             complement(22397..23149)
                     /locus_tag="ACIZD4_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC5989272.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(23164..24411)
                     /locus_tag="ACIZD4_000308"
     CDS             complement(23164..24411)
                     /locus_tag="ACIZD4_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGC5989273.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(24487..24633)
                     /locus_tag="ACIZD4_000309"
     CDS             complement(24487..24633)
                     /locus_tag="ACIZD4_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HGC5989274.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(24737..25048)
                     /locus_tag="ACIZD4_000310"
     CDS             complement(24737..25048)
                     /locus_tag="ACIZD4_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGC5989275.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(25050..25247)
                     /locus_tag="ACIZD4_000311"
     CDS             complement(25050..25247)
                     /locus_tag="ACIZD4_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HGC5989276.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(25641..27368)
                     /locus_tag="ACIZD4_000312"
     CDS             complement(25641..27368)
                     /locus_tag="ACIZD4_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HGC5989277.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(27361..28554)
                     /locus_tag="ACIZD4_000313"
     CDS             complement(27361..28554)
                     /locus_tag="ACIZD4_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC5989278.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(28741..29385)
                     /locus_tag="ACIZD4_000314"
     CDS             complement(28741..29385)
                     /locus_tag="ACIZD4_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5989279.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(29479..29613)
                     /locus_tag="ACIZD4_000315"
     CDS             complement(29479..29613)
                     /locus_tag="ACIZD4_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HGC5989280.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(29615..31747)
                     /gene="feoB"
                     /locus_tag="ACIZD4_000316"
     CDS             complement(29615..31747)
                     /gene="feoB"
                     /locus_tag="ACIZD4_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HGC5989281.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(31744..32217)
                     /locus_tag="ACIZD4_000317"
     CDS             complement(31744..32217)
                     /locus_tag="ACIZD4_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HGC5989282.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            32618..32842
                     /gene="nrdH"
                     /locus_tag="ACIZD4_000318"
     CDS             32618..32842
                     /gene="nrdH"
                     /locus_tag="ACIZD4_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGC5989283.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            33001..35160
                     /gene="nrdE"
                     /locus_tag="ACIZD4_000319"
     CDS             33001..35160
                     /gene="nrdE"
                     /locus_tag="ACIZD4_000319"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGC5989284.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            35210..36175
                     /gene="nrdF"
                     /locus_tag="ACIZD4_000320"
     CDS             35210..36175
                     /gene="nrdF"
                     /locus_tag="ACIZD4_000320"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGC5989285.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(36264..37403)
                     /locus_tag="ACIZD4_000321"
     CDS             complement(36264..37403)
                     /locus_tag="ACIZD4_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC5989286.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(37712..38425)
                     /locus_tag="ACIZD4_000322"
     CDS             complement(37712..38425)
                     /locus_tag="ACIZD4_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGC5989287.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(38679..39380)
                     /gene="nagB"
                     /locus_tag="ACIZD4_000323"
     CDS             complement(38679..39380)
                     /gene="nagB"
                     /locus_tag="ACIZD4_000323"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGC5989288.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            39614..41146
                     /locus_tag="ACIZD4_000324"
     CDS             39614..41146
                     /locus_tag="ACIZD4_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC5989289.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(41337..42539)
                     /locus_tag="ACIZD4_000325"
     CDS             complement(41337..42539)
                     /locus_tag="ACIZD4_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5989290.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(42621..43310)
                     /locus_tag="ACIZD4_000326"
     CDS             complement(42621..43310)
                     /locus_tag="ACIZD4_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGC5989291.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(43416..43784)
                     /gene="rplL"
                     /locus_tag="ACIZD4_000327"
     CDS             complement(43416..43784)
                     /gene="rplL"
                     /locus_tag="ACIZD4_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGC5989292.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(43837..44340)
                     /gene="rplJ"
                     /locus_tag="ACIZD4_000328"
     CDS             complement(43837..44340)
                     /gene="rplJ"
                     /locus_tag="ACIZD4_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGC5989293.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(44544..44671)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(44750..45439)
                     /gene="rplA"
                     /locus_tag="ACIZD4_000329"
     CDS             complement(44750..45439)
                     /gene="rplA"
                     /locus_tag="ACIZD4_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGC5989294.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(45543..45965)
                     /gene="rplK"
                     /locus_tag="ACIZD4_000330"
     CDS             complement(45543..45965)
                     /gene="rplK"
                     /locus_tag="ACIZD4_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGC5989295.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            46308..46976
                     /gene="sdaAB"
                     /locus_tag="ACIZD4_000331"
     CDS             46308..46976
                     /gene="sdaAB"
                     /locus_tag="ACIZD4_000331"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGC5989296.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            46989..47861
                     /gene="sdaAA"
                     /locus_tag="ACIZD4_000332"
     CDS             46989..47861
                     /gene="sdaAA"
                     /locus_tag="ACIZD4_000332"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGC5989297.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(47952..49052)
                     /locus_tag="ACIZD4_000333"
                     /pseudo
     CDS             complement(47952..49052)
                     /locus_tag="ACIZD4_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(49144..50031)
                     /locus_tag="ACIZD4_000334"
     CDS             complement(49144..50031)
                     /locus_tag="ACIZD4_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC5989298.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(50108..50653)
                     /gene="nusG"
                     /locus_tag="ACIZD4_000335"
     CDS             complement(50108..50653)
                     /gene="nusG"
                     /locus_tag="ACIZD4_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGC5989299.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(50754..50924)
                     /gene="secE"
                     /locus_tag="ACIZD4_000336"
     CDS             complement(50754..50924)
                     /gene="secE"
                     /locus_tag="ACIZD4_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGC5989300.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(50948..51100)
                     /gene="rpmG"
                     /locus_tag="ACIZD4_000337"
     CDS             complement(50948..51100)
                     /gene="rpmG"
                     /locus_tag="ACIZD4_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGC5989301.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            51262..51906
                     /gene="cbpA"
                     /locus_tag="ACIZD4_000338"
     CDS             51262..51906
                     /gene="cbpA"
                     /locus_tag="ACIZD4_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HGC5989302.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(51962..52465)
                     /locus_tag="ACIZD4_000339"
     CDS             complement(51962..52465)
                     /locus_tag="ACIZD4_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGC5989303.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(52478..52524)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            53062..54027
                     /locus_tag="ACIZD4_000340"
     CDS             53062..54027
                     /locus_tag="ACIZD4_000340"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC5989304.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(54126..55298)
                     /locus_tag="ACIZD4_000341"
     CDS             complement(54126..55298)
                     /locus_tag="ACIZD4_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989305.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(55285..56430)
                     /locus_tag="ACIZD4_000342"
     CDS             complement(55285..56430)
                     /locus_tag="ACIZD4_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989306.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(56444..57368)
                     /locus_tag="ACIZD4_000343"
                     /pseudo
     CDS             complement(56444..57368)
                     /locus_tag="ACIZD4_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            57485..58564
                     /locus_tag="ACIZD4_000344"
     CDS             57485..58564
                     /locus_tag="ACIZD4_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGC5989307.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            58561..59189
                     /locus_tag="ACIZD4_000345"
                     /pseudo
     CDS             58561..59189
                     /locus_tag="ACIZD4_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(59299..59526)
                     /locus_tag="ACIZD4_000346"
     CDS             complement(59299..59526)
                     /locus_tag="ACIZD4_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC5989308.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(59629..62217)
                     /locus_tag="ACIZD4_000347"
     CDS             complement(59629..62217)
                     /locus_tag="ACIZD4_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGC5989309.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(62237..62896)
                     /locus_tag="ACIZD4_000348"
     CDS             complement(62237..62896)
                     /locus_tag="ACIZD4_000348"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC5989310.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(62945..63448)
                     /gene="trmL"
                     /locus_tag="ACIZD4_000349"
     CDS             complement(62945..63448)
                     /gene="trmL"
                     /locus_tag="ACIZD4_000349"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HGC5989311.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(63669..64535)
                     /locus_tag="ACIZD4_000350"
     CDS             complement(63669..64535)
                     /locus_tag="ACIZD4_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HGC5989312.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNEVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            64644..65285
                     /locus_tag="ACIZD4_000351"
     CDS             64644..65285
                     /locus_tag="ACIZD4_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGC5989313.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(65347..66708)
                     /gene="mgtE"
                     /locus_tag="ACIZD4_000352"
     CDS             complement(65347..66708)
                     /gene="mgtE"
                     /locus_tag="ACIZD4_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HGC5989314.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(66726..67625)
                     /locus_tag="ACIZD4_000353"
     CDS             complement(66726..67625)
                     /locus_tag="ACIZD4_000353"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGC5989315.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(67627..68424)
                     /locus_tag="ACIZD4_000354"
     CDS             complement(67627..68424)
                     /locus_tag="ACIZD4_000354"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGC5989316.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(68402..69106)
                     /locus_tag="ACIZD4_000355"
     CDS             complement(68402..69106)
                     /locus_tag="ACIZD4_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGC5989317.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            69237..69812
                     /locus_tag="ACIZD4_000356"
     CDS             69237..69812
                     /locus_tag="ACIZD4_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGC5989318.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            69930..70607
                     /locus_tag="ACIZD4_000357"
     CDS             69930..70607
                     /locus_tag="ACIZD4_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HGC5989319.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(70686..72494)
                     /gene="pepF"
                     /locus_tag="ACIZD4_000358"
     CDS             complement(70686..72494)
                     /gene="pepF"
                     /locus_tag="ACIZD4_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGC5989320.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(72670..73668)
                     /locus_tag="ACIZD4_000359"
     CDS             complement(72670..73668)
                     /locus_tag="ACIZD4_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HGC5989321.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(73894..74547)
                     /locus_tag="ACIZD4_000360"
     CDS             complement(73894..74547)
                     /locus_tag="ACIZD4_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGC5989322.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        22630 a        15349 c        12730 g        24144 t
ORIGIN      
        1 acgaactgac tgatgaatct cagtttaacc tcgaaaaatt tatggaatat tattctattc
       61 agaataagct cagatacact tgttatgctg tctgccaatg ctattttaag aaaaaatatt
      121 cttacgcaag gcaatatgta tgaatacatc aagaattatt aaaaaaaccg atttcagcaa
      181 aacattaaaa aagcccgtgc tggcacacgg actcatacct catttctgag atcgcaaata
      241 tattataaca agaagtgagg aatatttaaa tggcaaaaaa agttatgggt caagacggaa
      301 aaatgtataa agttagtaaa cctttttaca aaaaagtatg gttttgggta ttagcagtaa
      361 ttttaattat aattattggt tctgctttaa atggtggatc agatagtaat aaagcaagtg
      421 ataatggtgg cgaaaaagta actaaatctt caacctctgc ttcatcttct aaagaagaaa
      481 aaagcgatac cttctataag attggtgaca ctgtaaaagt tggtgatgct gaatatacac
      541 taaatagtgt agaactaact gatgaaagaa atcaatttga agaaaaccaa cctgcacaag
      601 tagtaaaaat tacttatacc gtaaaaaatg atggcgattc agatatccct gtaggtacag
      661 atgtggaagt atatggacca gatgacaaaa aatcagagac atatgccaac gaaaatacaa
      721 tgggatctgt tgctccagga aaacaaatgg atgtaactgc tcatttcacg ttaaaccaaa
      781 agggagaaat agaaatccac ttctctcctt tagtatcatt tgaaaaagca gctattttta
      841 aagcaactgt ataataaata aaaaacacgc cccaccgtcc agagtaagag cgtgctttta
      901 gaaaacaaac ctatataggt ctatttgtta tgcctattat agcaaatgat aggagatgtt
      961 aaaagtgtgg gttgaacaaa ccaaagatgg ccaattcaag tttattgaaa gatatgtaga
     1021 tccttataca gaaaaaacac gaaaaaaatc tacaacactt acaagtaatt caccacaagc
     1081 gtggaaaaaa gctcagaaaa ttctagataa aaaaattaaa gaagcactcg aaaattacaa
     1141 taaatcagat atcacttttg gtgagctgta taaagaatgg tatgaatatt ataagcagca
     1201 tgttaaacgt actagctatt tgaaggttcc aatgatgatg aaacatgttt ctaagcacat
     1261 aagcgatgat acaatcgtta gaaacattga tgagacactc attaataaga tgattgaaga
     1321 tatgtacact tttggtgatc tctcactgaa ctacacaaag caaacaaaaa caactctatc
     1381 cgttatgcta aactatgcaa ttgatagaaa atacattcaa agaaaccctg ctctagcagt
     1441 taaaatccat cctaaaaaag tggaagaaga aaaaagaaag ctttctatgg ataaaaaata
     1501 tctggagaaa gaagaaattg atcaaatact gaaacagtta tattccaatc ctcgcagaaa
     1561 actacacggc ataatagctg aatttctata tttgactggt ttgagatatg gggaattgct
     1621 agctttgcaa atgaaggact atgaggatgg gaaaatttcc attaatggga ccttagatta
     1681 cacatctgtg aaaatggata atgctataaa aacaactcca aaaaatactt attcgcaacg
     1741 tgaagtgcaa ttacccaatc gtgcaaaaga attgattgaa agtgtgatag ctgacaatat
     1801 tcttgcaggt agacccacag atcccgatca atatatattt atatctacaa gtggcactcc
     1861 gcttacgctg cactcattta acgctatact ccataaagta gaggaagagt tggaattaga
     1921 aaaaagtcta tcctcacata tattcagaca tagccacgtt tcactattat ctgaattagg
     1981 cgtacctctt aaagccatta tggagcgtgt agggcattct gatgcaaaca caactctgtc
     2041 tatttataac catgtaacaa aaagagccaa acaacaagta attgataaac taaatagcct
     2101 ttgatatttt tgccccttct ttgccccttt tgcttaaaat aaaacaaaaa aagaagaaag
     2161 aaccctgtta aaatagggtt ctttcttaat tactacatca taccgcccat cattgatgga
     2221 tccattgcag gagctgctgg cgctgctggt tctggtttat ctgcaacgac tgcttctgtc
     2281 gttaataaca aggcagaaac ggaagcggca ttttgcaagg cagaacgtgt tactttagtt
     2341 gggtctacga tacctgcttc aaccatgttt acccattctc cagtagcagc attgaaacca
     2401 gtgcctagtt ccacgttctt caatttatca acaatcactg atccttcata accagcgttt
     2461 tcagcgattt gacgaattgg ttcttctaaa gcacgaacaa cgatcttgat acctgttgcc
     2521 acgtctcctt ctgcttctac agcagaaact ttgctgataa cgttcactag agctgtacca
     2581 ccacctgaga ccattccttc ttctactgcg gcacgtgtag cattcaatgc atcttcaatg
     2641 cgtaatttta attctttcaa ttctgtttca gtagctgcac caactttaac aacagctaca
     2701 ccacctgcta atttagctaa gcgttcttgt aatttttcgc ggtcaaaatc agaagttgtt
     2761 tcagcaattt ggtttttgat caattgcaca cgagcttcga ttgcttcttt ttctccagaa
     2821 ccttctacga tcgttgtatt gtctttatct acaacaactt tagaagcatt tcctaagttt
     2881 tcgattgttg catctttcaa ttctaaacct agatcgtcag taattactgt accacctgtc
     2941 aaaatagcga tatcttcaag cattgcttta cgacgatcgc cgaaaccagg agcttttaca
     3001 gctactacgt tgaatgttcc acggattttg ttcaatacaa gagttggcaa tgcttcacca
     3061 tctacatcgt cagcaataat caacaatgga cgtgattgtt gcaagatttg ttctaacaat
     3121 ggcagaatat cttggatgtt agagattttt ttgtctgtga tcaagatata tgggttttct
     3181 agaacagctt ccattttgtc gttatctgtt accatatatt gtgataagta accacgatca
     3241 aactgcatac cttctacaac atctagttct gtttcgatcc cttttgattc ttcgattgtg
     3301 atgacaccgt cgtttccaac tttttccatt gcatcagcaa tcaaatgtcc aactttatca
     3361 gaacccgaag aaacagctgc tacttgtgca atggcttctt ttgaatcaac aacagttgag
     3421 atattatgca attcttcgac tgctgctttt gttgccaatt cgatcccgcg acgaatgcct
     3481 agaggattag cacctgcagt tacgtttttt aaaccttcgc gaacgattgc ttgtgtcaga
     3541 acagttgctg tcgttgtacc gtctcctgca atatcatttg tttttgatgc tacttctgat
     3601 acaagttttg cacccatgtt ttcaaaatga tcttctaatt cgatttcttt tgcgatcgtc
     3661 acaccatcat ttgtgatcaa tggagagccg taagattttt ctagtacgac atttcggcct
     3721 ttaggtccta atgttacttt cactgtatct gctaatttat ctaccccgcg taacatagct
     3781 gcgcgtgcgt cttctgcaaa tttcaattct tttgccatga ttgattcacc tcattgatta
     3841 tttttgatta tttttttatc ttccaaattt actcaacaat cgccatgata tcttttcctg
     3901 cgacgatcag atattctttt ccttcgtatt ttacttctgt accggcgtat ttttcgaaca
     3961 taacttggtc gcctgctttt acagcggcag gaactttttc accgttttct aacaaacggc
     4021 cttcaccgac tgcaacaact gtcccagttt ggggtttctc tttagcagca gaagctaaaa
     4081 cgattcctcc gacagttttt tcttcttctt ttgcgacttc gataatgacg cgatcaccta
     4141 atggttttaa cacgataaat ccctccgata actctttttt taatctgtta gcactcttaa
     4201 ccttcgagtg ctaacctaca tttttaataa tactcattct ccctcttttt tgcaagcttt
     4261 taaatcaaag aaaagaaatt ttattctgac agctgcttat tgaaattatg atataattga
     4321 aatcaatcga tataagcttg ccttgcatgc ttgttatccc ttaaaaggag gaattacatg
     4381 tctttaaaaa aatatagctt cctcagcatt ttttgctatg gtctaatttt tatctcaccc
     4441 ttgatcctag cttcgatagg acttgtaaaa tctacgtctg aattgatcac agcaactgca
     4501 gtcatgtata tactaggcgc cgttgtccta gctatttttt attttaagca acgtgaaccc
     4561 ttagcgatcg aatcagcggt aaaaaaagct tctgctccaa agattgttat ttatggattg
     4621 gttggaatct ttgtcgcatt gattctgcaa agcatcgctg tcatgttaga atctgtattg
     4681 tttggcaaag caaccccttc cgagaataca caaaatatca tccagatgat catggaagca
     4741 cccgctttta ttttggcgac aactgttgct ggacccatca tggaagagtt cgtattccgc
     4801 cgcagtatac tggggatcat cagtcgatat tcaaattttt gggtcggagc agtgatcagc
     4861 tctttgctgt ttgcgtttgc tcataatgat ggtcatctgc taatctactt tttcctaggt
     4921 ttcttcttca gcctagagta caaagcaact ggtcggatct ggacatcgat gatcacacac
     4981 gtaggaatga acacattagt tgttcttgtt caattagctg tccaaaaagg gctagtataa
     5041 acatgactat aaatactcct gtcatcctag attggtgatt ttcccaatct aaagcgacag
     5101 gagtattttt gttttttagt cgttcatctt ttctgctgct ccatcatttt ttgtctgtct
     5161 ttcctttttg cagtttgcag aatctatttt tttcaaaaat gggaaataaa tgaaaaaact
     5221 aattgacaac acgatacctt gtaaaatcgc tgcaggcact ccgcctacta agaaacccga
     5281 gaggatcggc ggtgttgtcc aagggacttg gactgctgta aataaaggaa cgaatccaaa
     5341 atataaagcg gaataggtaa tcaatcctga aacgaccggt gcgaaaataa aaggaacagc
     5401 catcatcggg ttcatcacga tcggtgtgga aaaaataatt gattcattga tgttgaaaaa
     5461 ggctggtaaa agagcaagat ttcctaattc tctgtatttc ttcgatttcg caaaaaccgt
     5521 cataaaaaat acagccccta acgtcaatcc agcacccgta accgtcatga actgatcgag
     5581 aaattgctga gtaacgatat gtccgccatt tgccaccgtc aactcttgtc ctgaggctaa
     5641 gatttctgca tttgctaatg aattcgcttg caagacggga ctaaccaacc cattgaccat
     5701 cgcagatcca tgaagaccaa ataaccataa aaacggaaca aaaaaaccta ataaaagcac
     5761 accaaacaac gtgtctatga acgattgaat gggaagctgg acatatgtcc atactccttg
     5821 aacaacagtc attctgaaca aatgttgaaa aaccgctgaa ccgataagcg taaaagtgac
     5881 tataacaatg attggaatca atgaagtaaa agactgccaa acattttcag gtatcttctc
     5941 tctttgcttc caccctttcg caagtcttac taaacgtgca tagccccatc cgatgatgag
     6001 cccagttgta actgctccta gtatcccttc agcacctgtc cagacagtat ctatctgagt
     6061 atttagtggc tgaataagca gtagataagc agacaaggct gttatgccga ctggtaagcg
     6121 atcgatgtct tcttcttttg cataagcgta tgcaatggca aaaacgatcc aaaaggctat
     6181 cacatcaaat gtagcctggt atacttgtgt aaaatacata gaaaatcctg ttttgtctat
     6241 ccactgagcg atgtaatcca caggaaaatg agcaaataag aaaaacagcg agccaacaat
     6301 aattattggg atcgtgtaag tcattccatt acgcaaagca gttaagggtc taagattcac
     6361 aacagatgtt atcattggta aaaaggcacg atctaaccac tctttcattt cttatctcct
     6421 tcaacttcta tttttatcaa tcagttttct taatttaact atacccaatg atcacgaacc
     6481 atgaaaggaa tgcgcactga gcttttcaaa aatcggattc tttgacgaat attcagcaac
     6541 tgcttacaat ggacaggaat aaaaaaggag gttttttatg aaaattgcac tcattggagc
     6601 tactggccat gcaggttcat ttattttaga cgaagcattg tccagagatt tagacgtgac
     6661 ggcaatcgtg cgtcatccag aaaaattgcc atcagatgtt ccgtttatac aaaaggattt
     6721 atttgagttg acaactactg atcttgcatc ttttgatgtt gtcgttgatg ctttcaacgc
     6781 tcccaaagga aaagaagaaa tgcatcaaac ttctttgtcc catttgattg agatgcttga
     6841 aggaaccgat acacgcttaa ttgtcgttgg gggtgcctct tcgttattct tagatacaga
     6901 aaagacgact cgtatgattg accaagtacc taaaaatgca cccttctatc caacagcttt
     6961 caatatgtac gaaggattgt taaaattgaa acaatctaaa aatctacatt ggacttatat
     7021 cagtccagct tctttatttg atccacatgg caaacgtaca ggtacttatt tgttaagtga
     7081 tgattattta caaagaaacg ctgctagcga cagtacgatc agcatggcag attacgcgat
     7141 tgcattagta gatgagatac tggatgagaa acatgaaaag cagcacatca gtgtagtcag
     7201 tcgataatac ggttattttt ttaatatgct aaaaaaataa aaatagaaga taaaaccaac
     7261 cctgattgat tttatcttct gctttttata tttttattga ttgaactgtt taaatcgaaa
     7321 atagctcagt tgcttcatct ggatctgtat catagatttc aaaatcatgt ccaacgccaa
     7381 aatctttttc tttcaaaaca ttttccattg ttaaatgagc aagttctttc atattgtttt
     7441 ccttgctaag atggccaaga tagattcgtt tggtccgatt accgatcaca tcagtcatga
     7501 caagtgcacc gtcttcgttg gaaagatgtc ctctatctcc taaaatacgc tgttttaaat
     7561 tccacggata aggtcccatg cgtaacatct caagatcatg attactttcc atcaaataac
     7621 catcggcatt ttcaatgaca cctcgcatat aatcactgca atatccggtg tccgtcaaca
     7681 tgacgaatga ccgattttct ttatggaaac gataaaattg cggagccgct gcgtcatggg
     7741 agacgccgaa actctcaata tcgatatcgc cgaatgttct gactttcccc atctcaaata
     7801 gatgtttttg ttccactggt acatttccaa tcagtggttc catcgcttcc caagtctgct
     7861 gattggcaaa aacatccaaa tgatacttac gagccaagac acccacgcca tgtatatgat
     7921 ctcgatgttc atgcgtcaca agtattccat ctaattggtc cggtgtccga tcaatttgag
     7981 ccatcaagga agtgattttt ttaccgctaa gtcctgcatc gaccaaaagc cgtttttttt
     8041 cactttcgat ataaagtgaa ttacccgaac ttccacttgc taggatactg attttaaaag
     8101 ctggtttttc ttcagccatt tgactcctac ttcccttctt actttgtaaa cttttttcat
     8161 tatactcgct tttttattga tcttccactt ttggtacagt attgtttgtc acgatcgtat
     8221 tgctgaaagc gttgacgctc tcaatttgga ccactttatc gcttgtttcg atcgctacat
     8281 gccaaacagg aacatacaca tttttttccc ggactttcag aatacaggaa taagctagct
     8341 gacgccataa aatttttgat cctcttggta ttttgttatt gatgtacaat gtattgattg
     8401 cttcctcttc cgtatacagt tccgtctttt cgcgcagctg ctcgatatca gataaatgcg
     8461 tctgcatgta tttcgtgatg ctataatcat tatcgttttt ttctaaagaa agaacgattt
     8521 ttgctgtatc atcattgaat gggatgcctt catactcttg gcttgcttgg atttctagtg
     8581 gttcttcttc taaatgagaa aagtttttcg tgtacacata atcattaccg aataaaatat
     8641 tgtctttgtt agataaaaaa tcttccaagg aactactaat tttatctgga tcgatcacgt
     8701 tcttttcagc atctgaactg gataaagatt tcgtcaaaac atcaccgtct aaaaacacac
     8761 cacttgccag caagccgctt ttaccagcct tgcgataatt cgctaatgaa gtgctaagat
     8821 tggtctgctc cgcgctaaga taatagcctt gcttgttctc agacgaaatc ttccccgtgt
     8881 aagtgatatc gtcgctagcc agacgttgtt ggattgattc agtctgatta gagcgaatga
     8941 cattgttttc ttggtatacc gcgtcatgat aactgctgaa taaaaacaca ttcaacccta
     9001 aaaaagcgac gaaaaatatc cattcgattt ttttgaaatc caattaattc gcctccaatc
     9061 caggtaattt ttccagaagg tcgttagctg aataccagtt atctttatat ttcacatacc
     9121 attcaggtaa gagatcaacg acacgattcg tttctttgac attttgccat gtatagccaa
     9181 cgatcactga accaatcttg ttgctatctg ctcccttagc ttttaactgc tggatgattt
     9241 cattcgtact tgcaagttct acttcttcgt ctgaaggtat cggcacttga atcgtattca
     9301 aactggtttg gatattcact tgcacagaac cattcgtttc accgccaact tccacaccaa
     9361 tctgtcctct gctgtctgtc ccaaaaaccg ggaagccttc cacgaatatc cgataatcga
     9421 tcgtattgtc actgcggtca aaatatctga ggttccctaa agaactgcct aatttgctaa
     9481 tataggggaa actttcagaa aatacactag cattttcttt tttctctggc agctctccac
     9541 gaaaatcaac tacttgcgtt tccgaatgga tagacattgt ttcattccca ccgtaaaaaa
     9601 tcaattcatt gctttcatca ttatttttca cgctatctgg tttctggaaa aaagcatttc
     9661 taaaaagtgt atagggttgc tgtgacagga tataactata cttcttcagt ttgatcgaat
     9721 gtttcgtagc atattgcgtg tcgatcgtcg atggttctgt tgtcatttct gtccattttg
     9781 tgtcttttgc tgttaattct ttattgatat ctgtccaatt caacgaaata tttgcttcat
     9841 atacgagatg gttcgaataa ttcaaaaatc ggattttttt atttccttga tcgaattgta
     9901 ttctagtaaa atacatattt tcgctttctt ttgccaagtt cgacacatct aaatctaaat
     9961 caaatgcttc cttgtattct cttagcaaaa aaggcgcatt ataggccaac tcaaaaccag
    10021 agttcagatt tttcacctgt tcaaactgtg atttgtctcc tgaaactact tcagaaagct
    10081 ttccaaatct tgctttatcg atgatcaatt gcaatcggta cacgagattt tcactgttgg
    10141 tttcttggat cattcccgaa tggtgccatg taacatgaag cggaagaaag acttcggaag
    10201 tttttcgatt gctttgagac tcgatcattt gagtgtttgt ctcatctacg ttgattgaac
    10261 tttttcctgc tgggctcagc cagattgcat aagagaagta tatgcttaac gcaaccatca
    10321 aaatgagtcc tatacgaacg actttttcag agattctcat tcccaccatt cctcctcata
    10381 aggttcatat ggcagcgaga tataaaaagt cgaccctttt ccttccttgc tctctgccca
    10441 aatagcgcct cgatgcgcct taatcacttc tctagaaata gctaatccaa gtcctgtccc
    10501 accttgtgct cttgcacgtg ctttatctac tcgatagaac cgctcgaaca ctcggttcag
    10561 atctttttta ggaatcccca atccttgatc ggtgatactt aaaatcacgt tattatgcgt
    10621 ttctaataag cgacaagtaa tcgttccccc atctggtgaa tacttgatcg cgttattcat
    10681 gatattatcg actacttgga tgattttatc tgtatctact tcgacccaaa gatctctttg
    10741 cgtaaattca cgacggatct tataattttt ttcctgattt cccaccatca tatcaaaccg
    10801 gtcaagaaca aaattcacta actcgttgaa attgacatat tctaattgaa gctgggtatt
    10861 acctgtatcc atgcgagata gatttaagag gtcattgatc attcgaatca ttcggtctgt
    10921 ttcatctagc gttaccttca aaaaatttgg tgctacttcc tcgtctttcc acgcaccttc
    10981 gctcaatgct tcgatataac tacgcatact tgtcaacggt gtacgaagtt catgggaaac
    11041 attagagacg aattcacgac gttcccgttc tgttttttct tgttctgtca catcatgcaa
    11101 gacagctact aatccgctga taaaacctga ttcgcgacgg atcatagaaa agtctactcg
    11161 caagatcatc tgatcacttt ccaatgtact ggttgaacgg tcaagtacca tttcgtttgg
    11221 atcttctaat aatttccgca acgtatattc ttcttcgata tctaaaagtg tcaaaatcga
    11281 ttgtccgatt gcttcctcgt ttttgatatc tagcaaggaa acagccatat cattgatcgt
    11341 aatgacttta cccctgcgat ctgtcgcaat gacgccgtct gtcatatggg atagcacgct
    11401 atccaaacga ttgcgttcag cttccattgt atcttgagct tcttcaatac gttcagctaa
    11461 ctgattgaag gtatcagcca gctgtccaag ttcatcttgt ccatgcactt tgactttccg
    11521 actgtagtct cctctagcga ttcgaatggc ttgttctctc atttcaccga tcggctgtgt
    11581 aatcgaacga gcaactaaaa cagatacgat cattgaaata aatgccgcaa ttagtgaggc
    11641 agtaaagaaa atgactgctg tgttattgat ttccgaatat ttttgttcga tattactttt
    11701 gacgtaaaga gccccgataa cggcatcgcc ggtcggggac aggatcggtt gaacattgat
    11761 attcacccgt ttatcgtcgt tatctaaagc aacataacgt ttagtcgtga aatcattgat
    11821 atcaacataa tcatttttct ttcccacagc gctttgttca ttgacatcgg ttgttcctcg
    11881 gatgatccct ttttcgtcaa cgacccgtat ttcgatgata tcgctagtcg cactgttttc
    11941 aataaatctt ttgatattcg catttacctc ttcatcatct gcattatctt ttcgattcaa
    12001 ttccgggctg attgttgttg ctaatgattc caccgtttga ttcatatctt taataaatgt
    12061 attgatcgtg gaacgttcta aaccacgtat aaagtaggca ccaataattt cgatcgagat
    12121 caataaaatc agaataaagg taatagcgat cttaaaattg actgatcgaa aaaagcggac
    12181 ttttcttttc atccaattac tcctgttctg ggttacgcaa atagtaaccg acaccacgac
    12241 gtgtcactaa ataatttgga tggcttggat tatcttcgat cttttcacgc aaacgacgta
    12301 cagttacatc cactgttcgt acatctccaa aataatcata accccaaacc gtttgtaata
    12361 aatgttctct tgtcatcact tgtccaaggt gcttcgccaa gtaaaagagt agttcgaatt
    12421 cacgatgtgt taactcgatt gtttctcctc gtttcgtcac catgtaagct tctggatgga
    12481 tcgtcaaatc accaatcgtc aattccgcag gtgctgcctc ttctggttcc ttcgcagccg
    12541 tggcaccgcg acgaagattt gctttgacac gtgcaactaa ttctcggttg gaaaatggct
    12601 tggtcacgta atcatcggcg cctaactcta agcctaggac tttatcaatt tcagaatctt
    12661 tggctgttac cataatgatc ggcatatcat aagttttgcg tacctcacga gcaacttcta
    12721 agccgtccat tttaggtagc atcaaatcaa gtaaaatcaa atcaggttct acctcagcaa
    12781 ctttttccaa ggcttcttcc ccatcatatg cagtataaac gtcatagcct tctttggcta
    12841 aattgaattt gacgatatcc gaaatcggct tctcatcatc gacaactaaa acttttttca
    12901 taaagagcca cctcttatat attattgtca taccttctca ttataccgta tttctgcttt
    12961 tgtttcatct ttgcctataa aacaaaagag aaaattaaaa tgaaagtgca aaatacttta
    13021 ttattttttg ttctaacttc aataaaaaag gaaaacactg attttcacct cagtgtttcc
    13081 tttttttgat ttatccttct aaaacttgta caccgacacc caataatccc ggaccagtgt
    13141 ggactactaa tgccggagaa atctggccaa agtagatttg gtttgcttgt gggaactctc
    13201 ttttaagtct cgcttccatt tcaattgctt cttctttcgc atccccatgg gcaacagcta
    13261 agttgaagac ctttgcatta ccgatttttt ctttgacgta agcaaccgtt ttatccaaac
    13321 tttttttacg tcccctagct tttcctactg tgtaataaat cccttcttca ttacatgaga
    13381 tgattgggtt aagctttaaa gcggttccta caatagaagc aactaaaccg atccgtccac
    13441 ctttttgaag atattccaat gtcgcaacat taaagaaaac ttttgttctt tcgactaact
    13501 cattcagatt actgatcagt tgatcccatt ctactccttc ttccagccat tttgctgctt
    13561 ggatcgcaga aaaacctgca ccaataccaa tatttttcgt atctagtaca tatgcttcca
    13621 attcttcttg ctgttgtgca attaaacgaa ccacattata tgtcccgctc aatccactgg
    13681 aaattgttac cgcaagtacc ttttcataac cgtctttttt gatttgctca aagatttctg
    13741 tgatcgactc accatccggc aaagatgtac cagggatttc ctctggcaaa cgttgataga
    13801 tctcttcagg ggtaatgtca attttatctg tatatacctg atctttataa ataattttca
    13861 atgggatcat atacatctcg tattttttta tcaattcttc tggaacatcc gtacctgaat
    13921 ctactaaaat tgcgatttta ttgtttttca tttgttttct cctcttttaa atattcggtt
    13981 tctagaacaa tcgttttttc cgcaagaagt ttcattgcaa acgataaagt tgccgctctt
    14041 acagcaatat attctacagg ggttgcctgg tcgaattttt gcggatgaga tttaccttgt
    14101 gctaattggc tgaccatcca cacagctgct tcttgttcat cgcaaaatag attataggct
    14161 tcacgaattc ctactgtttt tccttggaac aatatccctt ctttgatttc aggaatagtc
    14221 aatacttgtt tcaacgtagt gattgcaagt aaaaatgcta cgtgttcttt gttatatctt
    14281 tttttaactg gtgctggtat caaacctagt ttaacgtaat tgtttaccat agaagaggta
    14341 agcaatggat gcttttctcc ttgtatcaca ggtgaaagat aacgatcaac taacgttctg
    14401 acttggtcca tataaagttc taagtcaggg agttcttccc agtgaggcag acggaatgtt
    14461 tctagttcct tcccccactc cattaattgc tgacgcattt tttccatcat aaccgctcct
    14521 tttttcattt cataaacatg atatcagact tatgataaac attcaatcta gttgctttaa
    14581 ctaggtgatt tgattagcgg gattccatga aaacaaaaaa caagaaggct aagccttctt
    14641 gtcttttatc gttaagaaca ggagacccgc cggggagacg gcgggaaagg agtaaaaaat
    14701 gaaaaaagtg ttagggtttg ttctcttgca agaactttgt ttgttggtat gcttatataa
    14761 tagcgagcaa atgtgaataa tctatgaatg atttcctata aggaagtaaa gatttttctg
    14821 attttcttta aatgtagtct tgcattttaa aattcttagt gctactatta ttaagtactt
    14881 tttgtacggg ccgttagctc agttggtaga gcagctgact cttaatcagc gggtcgcggg
    14941 ttcgagcccc tcacggccca ttgggtgcca aacccacgga acaggtaaat gttggtgcga
    15001 aagcatttcg aaaacattta cgctgttctt tttttatttt tcaaaataac tagggctttt
    15061 tatttttaac tcaaagtcca ctgtagccct ttggactttg agttaaaaaa gaagcataat
    15121 tatgaacagt aaagtttcta atataacaat aattcgagaa gctttgcaaa atcatgctgc
    15181 caatgaactc tctaaacata taggattaaa tctaagtact ataaaaggtt aaaaagtgaa
    15241 gaatatttaa tagaaaaact aaatttactt gctgctttcc ccttttccat taatacaaca
    15301 atcagagagt gtcttttttt cgaaaaaatt agaataaata aaagacacgt agttttttta
    15361 tctacatgtc ttccatcgac tacaagttat catttctcaa aacgtattta gcttttaatt
    15421 gattaatcgt ttcacgttgt ctacacattg cctaattaag attttcttat tagaagcatc
    15481 aatcccgcaa taatacctaa aactccagga attacccaca ataatgttaa aagaaaaaat
    15541 ggaataatag ataaaatgag taaactaata ccatagacca ctgttttttg attttttctt
    15601 actaaaaaac ctattatgaa aatcattatc gaaaaaacta gggtaattcc tccaaataaa
    15661 acaacattcc cgcttagatt gactaacata tctatatcct tactggttag ttctgtagta
    15721 tttaaagtag ttgaatcaat agaagataga aacataccac ccatcaatgc taaaagacta
    15781 cataaaatcc ctgttattcc actaattaaa atcaaaataa actctgtttt tctcttattc
    15841 atttaattct ctccagatta agtgttttag aattagaaat tttttgacca tagttaatag
    15901 cttctaatga acgaataaca accactgacg tgttagaaaa ataatcccca atatgttgtt
    15961 tcttgggcgt gaaagcagcc accaaatacc caatttgaaa tacaaaattt tttaatataa
    16021 acctacatat acactcacga ataaagatag tttgccaact tagctctttt tcctcaaagc
    16081 tcactactct tatcccaaaa atcattttcc caattgtttg tcctgaattc agcttagtca
    16141 aaagtacaaa ataggttaaa taaatagcta atgacgctat accataaaaa gtaataatgg
    16201 atttgtcaga ttccagtccc atgattttgt aaaagagacc tatagtagca tgggtgatga
    16261 tgctaataca aattaaatca ataagaaaag caaaaaatcg taaccaaaat cccgcaaata
    16321 cataattagg caaagtttca atgccactct tcttattcat tttatagccc tccatagtaa
    16381 tacattggtt ttggagtatc agaaaatcca agtttttcaa aaactgaaat tacacgatct
    16441 gatgtagttg cctttagccc ttgccattca gcaatcttat tacctaacca agaagaagca
    16501 aagccagttg tgtcattttt atattctata accgtcgcat cagttaattt cttctctttt
    16561 tttagggaat ctaatgcatc ttcagagtaa ccaatttgat ccaccaaccc attttctact
    16621 gcttggttac catcataaat tcttccatcc gcaagttctt tcactgcatt agtatccata
    16681 tttcttcctt ttgctacaac attgacaaaa cgatcataag cactcatcac aaattcctgt
    16741 ataactttat tctcttcctc tgaaggtttg tgttgaggtg acatcatatc ttttaatgca
    16801 ccacttttat acgtcgcatc agttacgcca agtttttcta ataagccaga ataatttaaa
    16861 ccagaaataa tgacaccaat tgatccagtt gttgtttctt ccgtagcaaa tattttatct
    16921 gaaccagcag aaatgtagta ccctccactt gccgctgtat ttttaaatgc agtatagata
    16981 ggaatatcta gctttttaat ttttgccatt tctttagcaa tctcagcact ttcatatatt
    17041 cctcccccag gtgaatttac ttctaataac actcccttaa ccgctttgtc ttcttgaatt
    17101 ttctttagct gtgttaaaaa attctgatgg ttatattgtt ccctactaaa aagattgctt
    17161 tcacctgtat ctgcaataac tccattgacg gatagtttga caatcttttt atttgatgcg
    17221 ccttcttcta acgtttcttc tgtgatttcg ttagatccgt aaaaaatctt atttattcct
    17281 gttagggttg tatttgatgc ttcctcttta tcttttcctg gaattagcgc gacgataatg
    17341 gatagtaaca ataatccgca cgctactccc acagcaatcc atcttctttt attcatataa
    17401 actcctccta tattcttagt aaaaataatt attttttatt tagaaacaca tcgacaattt
    17461 gttgccaata tgttttttct cctacaatta aagacaactc tccagttaat ccataacgaa
    17521 acggaaacga ttgagttgtt tttaacgttc ctttcactgc ataaaaaaca cctttctcag
    17581 tggcagtaga attttctgaa atttcatcta aagttccgtc gatcgtaatc ggagccccac
    17641 ctttttgatc caatttaaaa tgaaccttca tcccttcttt aatataggta ctttcattcg
    17701 caggtaaaag tgctgtaaat ttcatttttg atttttcgtg gatcggataa atttctgcaa
    17761 gcactgttcc tttggctagt tctgcttgtc cctttgtttc ttcatttaaa tgaaccgttc
    17821 cagatacagg agcttttagt attccttttg aaagttgatc gtccaaactt ttgataactg
    17881 actggttctt ctcttgtttt tcatttagct ctgtaactgt ttgttttaca gttgttattg
    17941 cttgttctag ctcttgcttt cctttttccg tttgactaat tctgtcattc tcagaagtag
    18001 ttggtttaac taatttagct ttttctgact gatactgttc tacttctttt tttagttgct
    18061 caatttgttc atttatgctt gctgaaattg tcagtttcac ttgatttttt tgatcatcag
    18121 aaacattatt tagttgttct tgccaattct catagtttgc catcatttct tttgaaaaat
    18181 cttttaatga ttgattatta ctccaagcta cctgtacttg ttgccattct tgtaatttac
    18241 tatctgaact ctcaatttgt ttttctagtt gtctttttgt cttttcgtat acttctaatt
    18301 gcttttgatc atttaattca ctttgcttca aagcgtagcg gagtgattct ttttctgaca
    18361 acatgctctt taattgatta ctgtagccaa aactgtcatc cgttgaaaac aaattttttc
    18421 ctttacttat actttcaata aatagctgag ccatctttat ttgttgagta atacgttggt
    18481 tttcttgttc tatctgagcc ttttcattct ctattaaaga acaatccaat ctaaccaaca
    18541 catcgtcctt atgaacaaat tgattttctt ttaggaagtt ttccattatt ttagcttcta
    18601 atggcacttg taacttctct attttttcgg ggttcaattg agccgttgtc cgaataacaa
    18661 cctctttttt agcaaaggtt aaaaacaatc caataataca taaaaaaaga attacagggt
    18721 ataacaccca acggtagaag ctatgatgtt gtttagtata gatactagaa tgttcgaacc
    18781 aattattatt ctgcataaat tgtttccctc tcctagattt cccataattt ttgatagata
    18841 ccatcggcaa aacgaagttc atcgtgcgtt cctttttcta ccaaatgccc ttcatggaga
    18901 actaaaattt gatcacatgc ttttgctatt ggtaaatgat gcgcaataaa aataatcgtt
    18961 ttttctttta aattgaggag ataattcata attgcatgtt ctaacaaggt atctaatcca
    19021 ctagttgctt catctaaaat taatatgtcc ggatttttta ataaagcccg tgctaaggct
    19081 aatcgttgtc gttgccctcc tgaaagatta tttccacctt cttccaacaa tgtctcgtaa
    19141 cgtaatggct gttgattaat aaattcattt agttggacta tctcacaaac ttctattatt
    19201 tgttcgaaac ttggtgggct atctaaaccg aatataagat tctcaatgat tgttccacta
    19261 aagaaaaatg actcttgagg caaatatgtc actcgatcgc gtaatatctg aaaaggaatg
    19321 tctaagtgat taatgtttcc ataatggatc gatccttctg atgcttcata aaaacgaaca
    19381 aataactttg caagagttga ttttccagaa ccactaactc caactatagc cgttttactg
    19441 tgcgaaggaa ttgtacatga aatttcgttc aacgttgggg ccttcatgct atacgagaat
    19501 gaaacgtttt ttacagtgat atcttgttga aataattgtt cagaaagcat atattcaaaa
    19561 gactggttcg atttttctga atcaatcgcg aaaatttcat ttaaacgatt atttgcaact
    19621 tgagccgttt gcattttcac ttgtaaatta ataatgtttt gtaaaggatc tgtcaaaaat
    19681 actagtaaag cattgtatgt gataagttga cctagactaa ttctattatc cataacaaaa
    19741 taagaaccta gccataaaat taatgcactg ctaattaatt gaatcaaatg tttaattcct
    19801 tgttgaatat tatcaagcgt aaccgtacga aatgattttt tcattaattt aacaaattca
    19861 tggtctatac ggttatatac tttctcttca ccgctatatg ctttaattgt ttctattcct
    19921 ttaagacttt ctatgatact agaatttaca gctgcaccgg ctgccatttc ttccctgttc
    19981 gatttttcat agcttttcac gaaagcgaat attgcaacta cataaaaagg caaagagcat
    20041 agagtgatta aaaacaacgt actattctga atagctaacg taaccccaac aagcaacacc
    20101 ataccaatat ctaaaaatat tgataacgta gcacttgcta aagcatcaat aatcttactg
    20161 gcatcaagaa aacgagaaat aatttcccct gattttctcg tagcaaaaaa attcattggt
    20221 aaagttaaca catgtttgaa atactgaagc ataattgcca tactcattcg ctgtcctaaa
    20281 ataataagaa gataactacg actatattca aacaataccc gaaataaata gacagcgatc
    20341 aagccaatgg aaattatatt taaagttgaa cgtgcttgat tagggatgaa aaaatcaaga
    20401 ataccttgaa aataatatga gcttcctatg ccaaaaaacg taatgaaaat cgatgctaaa
    20461 acgatgtgga atactaatcc tttttgtttc caaattatag gcaaaaaaga acttaatcca
    20521 gctacttttt ctttaatagg aatataagtt tctctaggca taggtaataa aagaatacct
    20581 gtccattctt tttgaaacgc ttcaatcgtt tttctatttt ttccattagc gggatctgca
    20641 atccatagta cgtttccctt cgttttataa attacaacgt agtgcatata gctgttatca
    20701 accaatatat gtgcaattaa tggtaagata agatctcttt ctttccagat ctcactatct
    20761 gcttgaatag ccatacaatc aaaagacaat ttttcaaatg tctttttcaa tccaaatgct
    20821 gaagtaccct ctaaatcagt cccagatagg tcccgtaatt tatgaatcgg gatatcagtt
    20881 ttaaaatatt ttaaaatcat cgaaaggcaa gcaacaccac aatctttttc atcttgttgc
    20941 tgcacaaaag gaaatgattt tatcacttat ctaacacaac tccttctaaa aaatttttat
    21001 agaaaaattc tcaatatagc tttaatacag tgaaaatatt gtctcataat tccacaaaaa
    21061 ctttgaaaac agttcttgaa cactaacttt ttcattcctg aatcaaattt attttggaaa
    21121 ttttactatt caagaataaa cttgataagt ttcaggaaga tttttactgt taatcaaata
    21181 cgtatgttac agtagcaccg taaaaaatat tatttaaaga agcgtgttta aacatgcaaa
    21241 atgtaaagga actaagtatt gtggaaatgc acaaactgtt ggtggaggca ataatgcttg
    21301 gggaaaattg gggcaagttg taggtggact taccacaggg gcagtaggtg gtgcaggttt
    21361 aggaacagca atttgcggac cagcttgcgg tgttgttgga gggttatatg gagctgtcgc
    21421 tggaggtgct gcagctggct gggatgctcg aaaaaaataa aaaaggagaa taagtagtat
    21481 gcatattaaa aacacaaaaa caacatttat attatcttca gaagagttga aaaatattca
    21541 aggtgggagt gccgtgggag ttttaggcac tactttttct ggggcaacag caggagtaaa
    21601 actttgttca gccggaggac cttatgcaat agctgcttgt ggtgtaggtg gagctttatt
    21661 aggtgctgga ttcagcatgt ggaccggtgc gtaaacaatt aaaaaatatc aaacctcaag
    21721 attggtttgt gtcgattacg aacataggta tgttctttat cttttcaaaa gtttggaatg
    21781 gacagaactt tttactaaag cttcttgtgc tagtttttat aattatatta aatttttatc
    21841 ttttattaaa gtcagataaa aattctttgg aaatgtaatg gtagagatat ttttacaaaa
    21901 ggacttgcag cgctgtagtt ggtgctgcag gaggacctat ttcggccgtt acaggaggta
    21961 ttggtaatgt acttgtcgga tgtgcattaa agcctgttcc tgcaagttaa atttataaaa
    22021 acaggaaagt aattatctca aatcctatca agtacaatca taggattgca cttgacagga
    22081 caaatttttt aactaaaaaa tgaaaaacac tttctaaaaa ttagtagaat ttgccaaatc
    22141 tttcgcatct tccaccatac atttaatttt aattcccctt tatggtactt aataaaaaca
    22201 agaaaagaac tattcatttg gccctttttt ggttccagac catagaaata ttcctccagt
    22261 aactaatatt gctgttatgc acgtaactaa taacagctat aaaaattggt acaactttaa
    22321 taggattcag aaaaatttgc actagtgaag gaatctattt tattagaaaa atgcaatctc
    22381 cctaaagaaa aaaccactaa acagtgcttt ctttcaactt ctccttaatt ttttgtgctt
    22441 tccctaaagt aaagtttctg gccaactctg aatcaaaata tagtgaacgt tttttaaaat
    22501 ctatttcttt aacgttaaag atatttacta aacacgctcg actaattctt gttaacatag
    22561 gatatttctt ttcaagctca ctaattcttc cataaaattc gtactgccca tctttagtac
    22621 acaatgataa tctatgtggt aattttgaag cttctacaaa ataaatgtca tttatatcaa
    22681 aagtaaatgt ttgagaacct atggaaaaaa caaatgcttg attcgtaacc tgttttgttg
    22741 catctatcct ttcttgcgct aataacaata actcaacaat ctcgtttcga tactcatcta
    22801 gtgtttgatc ttttgttaca aatcctaacg tttcaactct tctttttatt gttacgggta
    22861 acatctcatc atgagtagtt gtaaaaatga tttttgcttg aacatcatat tttctgatta
    22921 cttctgctaa ttctataccg ttaacttcat gatttaaatc aatatctaag aaatatattc
    22981 cttgctttgg tcggaattgt ttgaggtatt ttttaacttc taacggactt tgtgttttca
    23041 atactatctt aaatacttta tcgtgaaaaa gaatgaaatt atcaataatt cgttctaact
    23101 gatttaattg tataatttga tcttcacata atattattgg ataactcata aatcctcctt
    23161 ccctcaaaac aacaaaataa cttgagtagt aaattgatac ggatcgtttt gatagttcac
    23221 aaacatattg ggattctttt tattgatttc ctctatacta gataaaccta acccttgatg
    23281 tccctttttt gttgttattc cttttttcat tagagtatct atagagagta gtatctctct
    23341 acaactattc gatatcgaaa tttctatctg tttatcatct cggtaaatag ctagagacag
    23401 ttctctatct tgactctcta tagatgcttc aattgcatta tcgagaataa ttccaagcac
    23461 cctaatacag tcaaatattg gaacaggaac ttcaataata gtacttggac attcgaattt
    23521 acaacaaatc ttattgttat ttgcttggta tagcttcgct atcaacaaac ttttcaaata
    23581 ttcatttttt atatttttta aataacgata ttcaaactta ttggttagat aagaattaga
    23641 atagatctct aattctttta tttctttttc caatatcgaa tcatggtttt gattagcgat
    23701 ttcttttaaa ctcagcaata aatttttata gtcatgtcta aatctggcaa atttttcttg
    23761 atctttttcc agtgaatcag tatatttttt tagataaacc aattcttttc ttttcaattg
    23821 ctgttcatat tgttctcgtt gcctaatagt tattctaata aataaaaata gaacaacaaa
    23881 catttgaatg attaaaaata ttaagacacc aaacacaaaa tgatcaaata cttgatattg
    23941 atgagcaaca taagaaacaa ataaaccaat tgtaagtaaa taaatcatga atatagcagt
    24001 aagtttagaa ctggactgtt caacaatcct atttatagct aattttctat ataaccaaat
    24061 aaacatcagc aaaaacaaag aatcaagcat tatctggaat actacataac catacccttt
    24121 tatcccttca aatgaaaaca tatacgtcat aaccatggaa gtaataatag atctgaaatc
    24181 atcaataagc atacataata gtaatttatt taaaagcact atattagttt tcttcttttc
    24241 ctttaatata aaataacttc cgattatagg tatagctgcg gaaacatcag taaataattc
    24301 aacaaaaaaa gtgagtggta tcaataaaca tacaaaaaga tattttcttt tgttaagatc
    24361 agtattagtc atataaaata agagaaaaaa gaaaaagttt cccacgaaca ttcttaatag
    24421 ataagctttt gtatcgatag taatcaagag atcccctcct gattttagga tatcataaaa
    24481 aaaattttag ttacactttt taaataatga aaaaacacat tccactaaat ttgatgccgg
    24541 ttttccttga ggttttgttc cagcacctcc tttaattttt ttaagctctt gatctgaaca
    24601 ttgtttagca tttagtctat ttttttcttc cattacgatt ccccctacaa actataaata
    24661 cttttatgtc actgattcaa tatacctatt tttctaatca aaaaattttg agacatattt
    24721 aatattataa gtatcattaa aattgagatt tatctccata atctgctcga tataaaccat
    24781 ttattccagc agttcttcca atttcactca aatttcttat taattcctct tgatattcag
    24841 tgaatcttat tttattagta taagcagtaa aatatagata attcaccaat ctatttatta
    24901 aaggaccggg atctaattca tatttttgtt tttctaattt taaatatacc ttttgtaaaa
    24961 cctcaagaat atcagaatat ttaggatctt tacttataga tatatcatta tataattcat
    25021 gaacaatttg cttagcattt tttttcattt tagcacttcc ctggaattgc tccacctaaa
    25081 aaaccaccta tagacattcc tgcaatacaa gtagttgcct tggcccaatc gaccgtacat
    25141 ttatttttag tgcaatacac tccatttcca taatattttc cactatgagt ggtaccccca
    25201 tagataagtt gtgtctcttt aatagacaaa atttttaaat gtttcataat ctaatcaccc
    25261 ctaaattaat gtttttagac tattattcta acattcatta aatttcaaaa aacaattcct
    25321 tcttgaaacg tagcaaaata attcctgaat aagaatttaa tcacttttaa gtatataaac
    25381 tatgtatatt ctttaatatt ttttgagaat gcacttcgta cataataaac tttaatcaca
    25441 ttagtctttc atacctacga tcgatctctt tgactcgcac ccataaattc ataatagttt
    25501 gtcggcgtct ttggacgttt cgaagatgag ctacgcattc tcttttttta tagacaaaaa
    25561 agatagagac gaacatggag cttccaaatt tggatatttg atccaatttt ggaagctcca
    25621 tttatttcgt gtctgtcttt ttattttttc cagctttcga ctaattcttg gttctctttg
    25681 atccagtctt ttgctgcttg ctgtggatct tttccattgt tgatttccaa cataactttt
    25741 tccatatctt tttctgacca atggaaattg tctaatactt tgtaagcttc tggctggtct
    25801 tctttcaatc cttttcgaac catcgtatgg atctgctctt cgcttcccat tccgttttca
    25861 ggatcttcta agtatttcag atcatatttg gcaaacatcc aatgaggtgt ccatcctgta
    25921 actacaattg gttcgtgttt tttgatcgct tgacctagtg caacggtcat tgctcctgaa
    25981 gaagatgtct ctactttcca gtctttcaag ttgtcatatt tttggatcgt gttttcagca
    26041 gccgtaacta caccagctcc tggctcgatt cctatgattt tcttacctgc ctgatcggtt
    26101 aactcatcga tcgaatttac atccatgtag gctggcactg ctaaaccaac ttttgctcct
    26161 gtcaaattgg cacctaggtc ttcgacttga tctttatatt gtgcatattg tgaaccatga
    26221 gttttaggta gccaagctga aaccatggca tctgactcgc catttgaaac agatttccac
    26281 atgattgaat tatctaatgg cgtcatcgtt acatcatagc ccatttgttt caatacttca
    26341 ccgactacat ttgttgaagc aacttctgta tcccattcaa cataagataa gttgatacgt
    26401 tttgtttctt tggcagatga aaaactccct ataccaatcg cacctaagat cactactact
    26461 acagcaccaa tgatcagtcc ttgacgtttt ttacttttct gtgttgttgc tcctgcagct
    26521 tttttattgt ttggctggtt caaatgctgt gtaaaacggt caatgatgat tgctaagata
    26581 actaatgcaa ccccgttgac aaatccattc ccgacttgtg ctctttgcaa tgctgataat
    26641 acgccgcgtc ctaagccggg tgcaccgatc atagaggcaa taacgaccat tgaaagtgac
    26701 agcattgttg tttgattgat ccctgccatg atcgtacttt tagctaaagg caattctagt
    26761 ttgaatagtt tttgacgact tgtgctcccg aatgaatcag aagcttctac taattcttta
    26821 ggaacttgtc gaatccctaa attcgtaaaa cgaacggttg gtggcagagc aaagatgact
    26881 gaggcaaata cccctggaac catcccgata ccgaaaaatg caactgctgg aatcaaataa
    26941 acgaatcctg gcattgtctg cataaagtca aggatcggtt tgataatact ttgggcttta
    27001 ctgctttttg ccatcaagat ccctaatggt accccaatga tgatcgagat cacactagat
    27061 aaaagaacaa gtgtgacagt attcatcaaa tcattccata gaccttggtt ataaataaac
    27121 catagaccga ttaatgtgaa caacgtaagt cctggacgtt tcttagaaat aaagaaagct
    27181 gctaccgtca ataacaagat aaacaaagga gctggaatca ctaacagtaa atttgtaatc
    27241 cccgacatca ctgcctgtcc aatcgtttgt aaaaatgaaa ataggccaga aaaagttgtc
    27301 gtaaaccatt ctgtgatatt ttctacccag tttgccactg gtaattgata gttcaataga
    27361 ttattcatgt tcactcacct cgcttgtttc tgctaatgct tcaatcacac tacctcggat
    27421 gacgacacct tttaattttc catcctctac aactgcaagt ggagtcggtg agtcataaat
    27481 aatattgaaa atatcactta ccaccatgtc tttcccaatc accgtcacat tttcatctag
    27541 gaagtcgatc aatggacgtt tttgcttcct agcttctaac gcttgatctg cagtgatgat
    27601 ccctttcagg tgtctctttc tgtcaacagc catcagcatg ctgacttctt cattacgcat
    27661 ccttgtcaat gcaacgtttg gtccatcaga ttcgatattc gtcgtcaatg caggtaccat
    27721 gatgttttga gccgtaagca ctttggaacg atcgacttct tccacaaatt cacgtacata
    27781 atcatttgct ggattggtca atatttcttc acctgttccg atctgcatga tttcgccgtc
    27841 tttcatcaag gcgattctgt ccccaatccg taaagcttca ttcaaatcat gggtaatgaa
    27901 aataatcgtt ttttgaacat tggcttgcag gtccagtaat tcgtcttgca tttctcgccg
    27961 gatcagcgga tcaagagccg agaacgcttc gtccatcagc aagatctcag gatcatttgc
    28021 taaagctctg gctaggccaa cccgttgttg catcccacca gataactgac taggatattg
    28081 gtctttaaat gaaagcaaac tagaattttc taatgctttt tctgcttttt cttgtcgttc
    28141 ttctttaggt acaccacgga cttctaaccc gtattctgta ttttccaaga tcgttcgatg
    28201 tggaaacaga ccgaagtttt ggaaaaccat attgatttta tgacgacgga cttctcgcaa
    28261 ttcttctttg cttaacttcg atacatcttc tccatcaata tagatactgc ccgaagttgg
    28321 ctcaatcaga cgattcaata gacggatcaa tgtggatttc ccactcccgg aaagccccat
    28381 gatcacgaag atttctcctt cttttacgtc aaaattcacg tcatacacac caaccgttgc
    28441 accggttttc tttaaaatct ccgttttcgg ctggtgatca ttcatcatat ctaaagcggc
    28501 ttgtgtcttt ttaccaaata tctttgttaa atgttttact tctactttta ccaaacaaat
    28561 tctccttttt tatgtaaatt catttttctt tctgaaaaaa gtgaccacac tatgttaaca
    28621 tcatgtagtc actttgtcaa aaatgaaaga aatttgcttg tccaaactga aaaaaacttg
    28681 gctaaatctt tgtaaataaa aggtttagcc aagttaatat ttttttaata tttcacacaa
    28741 tcattctgca agctgatgct ccgggtaaaa aaagtttgtc atacgctgta gtgtatattc
    28801 atttccaata aaatgaacga tgtcccctgc cgtaaattta gcataggggc caggtgaaac
    28861 aagcagttct tcattatgag aaattgcgat aactgtggcg ccagtcgcct gccagatatt
    28921 caactcgcta attgaacggt ccagatgcat tgctttttct gataaagata attcaaacgg
    28981 aagtaaagga ttcatcttat gtattcgctt cgtttgattg accagctgat ccaataattg
    29041 agaaaaatga ttcagctcat cttgttgctt ctccacactt gccatgattt ctgcttttgt
    29101 atcttggatg gattgtacat cttgatattg caataggaaa tcttttgctt tttccttcga
    29161 agcaacaaat gccccacttc catgccgtac ttccatgatt ccaagatcta ccagcacatt
    29221 gatagccttg cgggtagtct caggagaagc attgtacgta ctggcaagtg ttgagcgggc
    29281 atggatcttc tcacccactt tatatcggtt ttcaacgata cgttcggcta aatcaacagc
    29341 aatctgctgg tagcgcgggc ggacgatttt tttctttcca gacattttct ttcctctttc
    29401 tttttttact ttccctcatc ttactatgct ctagcaaaat aagcaaaaaa ggggagaata
    29461 gcctcttgca acgactgatc atcgcttgat ctgttccttt tttactgggc aagctgtttg
    29521 acagtcatca caattcttac cggattttaa acgagtatag acaattgcgc ctgcacttcc
    29581 aaagattaac acacttaata agaatgtcgc catcctattc ctctccttct aatgacaata
    29641 tagtataaaa ctggttcttg gattttggct gacggaacaa aacataaacg agtcctatca
    29701 tcagtaaaat agcaagatac gtccctaacg ctacctgtcc accctccaat aagtgtccca
    29761 actgataaat cacaaaacta actaaataag ctaaaccgca ttgatagcct atggcgatcc
    29821 aagtccattt cttggcattc atttcccgat ggatagcccc aattgccgca aaacaaggcg
    29881 cacaaagtaa attgaaggct aacaatgaat aagctgctgc gggagtatat gtgtgttgta
    29941 gcacttgcca gatttctctg ccattttcgg atacttccgc atgaccaaac aaaataccaa
    30001 atgtgccaat aatattttct ttagcgacca atcctgtaat cgctgcgact gttccttgcc
    30061 agtttcccca accaagcggc tgaaaaacaa ctgccaggat tcgcccgaaa aaggctaaga
    30121 tactttggtc ttcagaaaca ggttgagcat aaaaattata agaagagctg aaccagatca
    30181 cgatactaga aacaaagata atcgttcctg cttttttaac aaaagacttg ctgcggtcat
    30241 aggtttgtct taggaccgct gaccattgag gaaaatgata tgcgggcaat tccatgataa
    30301 aaggagctgt atctccagca aacaaacgtg tttttttcaa gctgattcca gagaaaataa
    30361 ttgcagtcat accaagaaaa taggcagaag gagctaccca agattgatga ggaaaaaagg
    30421 cccctgctac taaggcaata atcggcaact ttgcagaaca aggcatgaag gttgtgacca
    30481 tgatcgtcaa acgacgatct tgctcgtttt caatcgtgcg actggccatg acgcctggca
    30541 ctccacatcc tgtagcaatc agcataggaa tgaaggattt tcctgaaaga ccgaatttcc
    30601 tgaaaagtcg atccatgaca aaagcgatcc tcgccatata tccgcagtct tccagaaagc
    30661 tcaagcataa aaacaatata atcaattgcg gtagaaatcc taacactgct cccacgcctg
    30721 cgatgatgcc gttcaagatc agctcctgca tccatcccgc tacttgccat tcagctaaca
    30781 atctgccaac atgttctggt aaccatgtac caaacaatgt gtcattgatc caatctgtcc
    30841 ccattgttcc tactgtttga atagccagat aatagatcag ccacatcaca aatgcgaaga
    30901 tcggcaaggc taaccaacga ttcgttgcaa tctgatcgat tttgtcactc atcgataatt
    30961 ggaaagaatc atttgacaca acacagagtg tacatagttg ggtaataaat tcataacgtt
    31021 cattgaccag aatcgtctca ctatcgtcgt ccaatagttt ctctgttaac tggatcagtt
    31081 gctcgatctc tttttgctga gaaactgcta tctcgtaatc ctctcttacc ttctgatctc
    31141 gttcaaaata tttcattgca taccagcgtt tcttgccgct ttgttctcct agtacatctt
    31201 caatttcatg taaagctgct tctaaacgtg gatcatatgt acagggaaca ggaatagaag
    31261 gccgcttttt tgcagactcc tgaatctttt cgattagttt ttcgattcct tgctttttca
    31321 atacgctgat tggtaaaact ggtacaccaa gaccatagga aagcttttct agattgattt
    31381 tttttccttc ttttttgatg acatccatca tattcagacc aatgatcata ggaatgtcta
    31441 aatccaataa ctgcgtagtt aaataaagat ttcgttctaa attggtagca tcaataatgt
    31501 tgatgatcag ttcaggctgt tcctgaacca aataatctct tgcaatcact tcttctggtg
    31561 tataaggaga caaagaatag atgccgggta ggtcctgaat atgaatgttc ggattttttt
    31621 tcaacgatcc ttcttttttt tctactgtta cgcccggcca attccctaca tattgattcg
    31681 aaccagtcaa gagattgaac aagctagttt tcccgctgtt tggatttccg actaacgcga
    31741 tattcattct ttttcctccc tttgtatcaa gattagttcg gcctctgact ttcgtaacgt
    31801 cagttcatac cctcgcactg tcagttcgat tggatctccc agaggggcta gttttcggat
    31861 aactattttt acatttcgcg tcaatcccat atccattaac cgtcgcttca ctgcgccttg
    31921 tccgtggatt gctacgacga tcccagtctc tcctgctttt aattgatcaa gagaagtcca
    31981 gctttcagag gaagcagtct ttttattgac aaagatttga cctagtattt cccgacttac
    32041 tgccactcga tgacttttta ccagtaaaat ggcattgttg cctgataaat tgacgacgac
    32101 gattttactt ccggcaacga tcccgatatt ttgcaaatgg cgttttgttt tttcttctgt
    32161 ttcgattcgt tcgacttgat aaacgaaatt ctgctttgcc tgcgctaagg tctgcatatt
    32221 gattcctctc ttgtgaaata aatcatgtat taaaatcatt cattatatgt tctaattttc
    32281 ttacgtgtta cgcaaataaa tgagaatcat tctcacatag aatactctcg gtaattgaga
    32341 atgtcaatta tacttgtgat attatgagcg aatctttagt attgatagat aaaaatgaga
    32401 aaaaaatatt tcttcatagt tttccacaat tttttctcta ttaaatttgc tattttccca
    32461 cacgatactt gttttcagct cttttttcaa aaacacaaaa cttagtattc cacagtttcc
    32521 acaacacaat atgtagtgtt tgttgtttga cttttttact aagagtttta tactatctat
    32581 tatagataat aagaatgtgt tagaggaggc actcaccatg aacgtaaaaa tcttttctaa
    32641 aaataattgt atgcaatgta agatggtcaa acggttttta acagaaaatc aaattgcttt
    32701 tgaagaagtc aatatcgatg aacagcctga agcagtagac tggttgaaag cacaaggatt
    32761 ccaaagtgtt cctgtcatta cttctgatgc agaaacagtt atcggattcc gtcctgatca
    32821 gttgcgtaaa cttgccagct aacatgacta aaagaatcaa aacgtgatac atggatttga
    32881 agggcttgag acagcaccag tttttgtcgc aaacttccaa atcctttttt aaagcttaaa
    32941 aacaatgcaa tgatttgcaa tcaagcatca tcaaatacga aatgaaggtt gggcgtacgt
    33001 atgagtctta aaaatttaca agatgtcagt tatttcaagc tgaataatga aatcaatcgg
    33061 ccagtcaatg gtcaaatccc tttgaataag gataaagaag ctttagttgc cttttttgag
    33121 gaaaatgtca aaccaaatac gatgactttt ctatctatta tggaaaaaat caattacttg
    33181 atcgatcaag aatatataga agcagaattc attcaattgt attcaccatc atttattgaa
    33241 aagctatatc aatttttgga cgagcaacat ttttctttca aatcttttat ggctgcttac
    33301 aaattttatt ctcaatatgc gttgaaaacc aacgacggtt ccgcttatct ggaaacttat
    33361 gaagatcgag tagccttcaa tgcgctttac tttgcgaacg gggatgaaga attagcactt
    33421 gctcttgcag acgaaatgat ccatcaacga tatcagccag ctacaccttc tttcttgaat
    33481 gctggacgta aacgtcgggg cgaattggtg tcttgtttct tgactcaagt cactgacgat
    33541 atgaactcta tcgggcgctc aatcaactct gctttgcaat tgtcccgtat tggtggcggc
    33601 gtagggatta ctttatcaaa tcttcgtgaa gccggcgctc ctatcaaagg atatgagggt
    33661 gctgcaagtg gtgtcgttcc agtcatgaaa ttattcgaag atagtttcag ctattctaat
    33721 caattaggtc agcgtcaagg agctggcgtg gtttatttga acgttttcca tccagacatt
    33781 attgctttcc tttcagcaaa aaaagaaaat gcagatgaaa agattcgcgt aaaaactctt
    33841 tctcttggcg tgatcgtacc tgataaattt tatgaattga cacgtaaaaa cgaagatatg
    33901 tatttattta gtccatatag tgtcgaaaaa gaatatggtg tcccattctc ttatgtaaat
    33961 attacagctg agtatgatca tctagttgca aatccaaaca ttcgcaaaca aaaaatcaaa
    34021 gcgcgtgatc ttgaaaatga aatctcaaaa ttacaacaag aatctggcta tccttacgta
    34081 atcaatattg atacagcgaa ccgcgagaat ccaatcgatg gcaagatcat catgagtaat
    34141 ttatgttcag agattttaca agttcaaacg ccttctgtga ttaacggcaa acaggaatat
    34201 gaagtattag gaacggatat ctcatgtaac ttaggctcga caaatatcgt gaatttgatg
    34261 caaagcccta actttggtca atctgtgcgt acgatgactc gtgcattgac atttattaca
    34321 gatgcatctg atatcgatgt cgtaccaccg atccaaaacg gaaataagct gaatcatacg
    34381 attggattag gtgccatggg cttacacact tatcttgcaa aagaacaaat ggaatatggc
    34441 tcagaggatt cattagactt tacaaatatt tacttcatgc tgttgaatta ttggacactt
    34501 gttgaaagca acaatatcgc tcgtgaaaga aaacaagttt tccataattt tgaaaaatca
    34561 gcttatgctg acggcactta tttcgaaaaa tacgtaactg gagaattcca gccaaaatca
    34621 gaaaaagtca aagcattgtt tgaaggcatt tttatcccaa ctgctgaaga ttggaatgct
    34681 ttgaaacaag cagtaatgaa agatggactg tatcatcaaa atcgcttggc agtagcacca
    34741 aatggctcaa tttcatatat caacgatacg agtgcaagta ttcatcctat cactcgcatg
    34801 atcgaagaac gccaagagaa gaaaatcggt aaaatttatt acccagcgcc ttatctatcc
    34861 aatgagacga ttccgtatta cacttctgct tatgatatgg acatgcgtaa agtaatcgat
    34921 gtttatgcaa tggcacaaca acacgtcgat caaggcatga gtttgacttt attcatgcgt
    34981 tctgaaatcc cagaaggcat ttatgaatgg aagacaacaa cgaagcaaac gacacgtgat
    35041 ttgaatattt taagacatta cgctttccac aaaggaatca aatccattta ttacgtacgt
    35101 acctttactg atgatgcaga agaaatcgga agcaatcaat gtgaaagctg cgtgatctaa
    35161 tatcatagat agattcgctt attcatattt taattaaagg agcattctca tgtcagaaac
    35221 atattatgaa gcaataaact ggaatgaaat tgaagatatc attgataaat ccacttggga
    35281 gaagctgaca gagcaatttt ggctagatac acgtatccca ctttcaaatg acctagatga
    35341 ttggcgtaca ttgtctcaat tggaaaaaga tacagtagga catgtatttg gcggtttgac
    35401 actgctagat actgtccaat ctgaaagtgg catggatcag ttgcgtaaag atgtccgcac
    35461 tccccatgaa gaagccgttt tgaacaatat tcaattcatg gaatccgttc atgccaaaag
    35521 ttattcttct atttttagta cactgaatac gaaaaaagaa atcgaagaaa tttttgactg
    35581 gacaaatacg aatccttatc tgcaaaaaaa agctgagcgt atcaatgaaa tctacaaaca
    35641 cggtacaccg ctagaaaaga aaattgccag cgtcttttta gaaacattct tgttctattc
    35701 aggtttttat actcctcttt attatttagg aaacaacaaa ttggctaacg tagcagagat
    35761 catcaaacta atcatccgag atgaatctgt acatggaacc tacatcggtt acaaattcca
    35821 attaggattc aacgagttac ctgaagcaga acaagaaacg ttaaaagact ggatgtacaa
    35881 tcttctttat gagctttacg aaaacgaaga acgttataca gaagaattat acgatccaat
    35941 cggctggaca gaagaagtca agacattcct acgctataat gccaacaaag cattgatgaa
    36001 cctagggatg gatccactct ttccagatac tgccaatgat gtcaacccaa tcgtaatgaa
    36061 cgggatttca acaggcacaa gcaaccatga cttcttctca caagtcggaa acggctattt
    36121 gttaggtcat gtagaagcga tgaaagacga cgattatttg attggattgg aataaggatt
    36181 tattttaatt caaaaatttt tcgaaaaata aaaagagttt agcgtacaga tattttaaat
    36241 gtacactgaa ctctttttta tgcttattca cttgtttctt ccagcacttt tggactgtct
    36301 aacttttccg aaacatgttc cattcttctc aataaataga ttttccggat atttaatatt
    36361 atcgtcttaa tcactgcata gacaggtatg caaatcagca tgcctaatat tcctgcgaca
    36421 cttcctgctc caatcaatac caagatgatc gtcaaaggat ggatattcat tgatttccca
    36481 aataacaacg gcttgatcaa atttccatct aattgttgga tcactaaaat cgacaacgcc
    36541 atatacaaag cttgaaatgg agagataaac aaaccgacaa tgattgctgg taccgctcca
    36601 ataaaagggc cgacatacgg gataatattc gtgattccgc aaatgaccgc aagcaacaag
    36661 ctataaggct gatcgaatat tctcattgcc aaaaagctca ttacaccaat aatcaaagca
    36721 tctaagatcg tactgctgat ataggcagat aatgtttcgt ttaattcttt taccgtttgg
    36781 cgtaactctt tacgaatcgc tttcggaaag aagtgagaca acgcatcaat aaatttgtgc
    36841 ccatccttga acataaatag caaaataaat ggaacggtaa ataacaaaat aaaaaattgc
    36901 atcataaatg aaatgatttt tgagacactt gcagataaac tgactaatat gatattgaac
    36961 aaattactaa gagataaatt tgctgatgct aattgttctt ccaaattgaa atttttaaac
    37021 tcttcccgct gcgccaattc atttaaccat ttgcttgttt catctgcata cattggcaag
    37081 ctctgggtca attgaattgt ctgttccatt aactgaggca ctacattcat gacagttaaa
    37141 acaactaaaa tgattacgac caaaaacgtc aataaaaaac cgaacactct cgggatccga
    37201 tgcttttcga gaaaaacaac gattggatcg aacatataat agataaaacc agcaacaagc
    37261 aatggtaaaa aaactgccga aagcattttc aatattggac taaaaatatt cggcatttgt
    37321 aaaataaagt acacgccgat gatcgtgagt actagctcca ctgtccagaa aaataatttt
    37381 gattgtttaa aacgtgattg catacatctc ctccaaggtc ctttgatact tctattctat
    37441 catttaacaa agagttacgc gctgagattt tcatttgctt aaaaaaaaca aaaaaaataa
    37501 acatatttta atgagtagac gagtacttaa acaaaaacac ggtttggagt agtgacaaaa
    37561 attatactgc agtccctttt tccaaataaa cggtgttcaa aagcttgcat cttcgtaata
    37621 agcccagcca aacgaaaaat ataaggaact atttttattt ggctgggctt attacttgat
    37681 gtaggacatc tattttacaa cctcagatca tttattgcgc aatactgact aaatgcaact
    37741 ttgtgatatt tttgtgtacg gacaactcct cgatcacatc ggcataagtg agcccttttg
    37801 gaagatcaat cgtatagata tttttgtaca ctcggtagtc atcaacgaat tttacgtcaa
    37861 aattcacatc ttcgattacg atatttttct cttcaaaata atcggtaaga aaatctttgg
    37921 tttcttttct atggataaat tggatttcta actttttagt cgtaggtaca tggatcacgc
    37981 gtttcactac tgtgagtgca atagcaatcc cgataaaact gatgatcgca atggaatagt
    38041 aacccatgcc gatggcgatc cctaatccag caattgccca taaagaagcg gcagtcgtaa
    38101 gtcccgtcac cgattgtttc gtgacgatga tcgttcccgc gcctaagaaa ccgacaccac
    38161 tcaccacttg agcaatcagc cttgcttcat ctgaacgaat cgttccagca agctgtggat
    38221 actctaaagc atctcttaat gcaccactag cgatctcaac ttggatcaat gcaatgatac
    38281 atgctcccat acaaactaaa atatgcgtac gcatacctgc tggacgattt ttatattgtc
    38341 gttcaaaacc gattgctccg ccaaatagca tagcgatccc taaacgtaaa ataatctctg
    38401 gaattgtcaa taccatatca ttcatctaaa caccctccag tccaatatat catgtctgaa
    38461 aggagcagac aaaaaaagtg caatttttac ctcttacgaa aaaaggactg tgacaaaatt
    38521 tttgtcatag tcctttttat gaataaacgg tgttcaatca gctgaccctc ggtattactc
    38581 aacaaacggc aaaatatggg gagctatttt tcctttgtct tctctaatac tcaggtcaaa
    38641 acgctgattt cacaacctct ttagcctact attgaaaatt acaacttact tgctgcttct
    38701 tcatcgatga tcacaacaac attgtcgtga ttttgcaata cacttgctgg caaatgattc
    38761 gttacaggtc cttcaatcat ccctttgatt gcatcagctt tgctttcgcc aaatgccatc
    38821 aagacgattt ctttactttt cataattgaa ccgattccca ttgaaacagc ttttgttggt
    38881 acatcttctg ctttatcgaa gaatcgtttg tttgcattga ttgttgattc tgttaagtca
    38941 actactgaag tcgttccgtc aaatgaagca ccaggttcat tgaaaccgat atgtccattt
    39001 tgcccgattc ctaagatttg gatatcgatt ggatgtgcat cgatgatttg atcatacttt
    39061 ttgcatgctg cttccagatc ttctgctttt ccatctggta caaacgtttc tttgaatggt
    39121 tttttatcaa ataattggac atccatgaaa tgacggtagc tttgttcatc tgaaccgcct
    39181 agtccaacgt actcatctaa gtttacagaa gtcatttcac tgaaatccaa atcgcttgaa
    39241 gtcatttctt tatataaagt aactggtgtg cttcctgttg ccaatcctaa tacttttgca
    39301 cctttgttca taccttcttt gatgatttca aatgcttttt ttccgccttc ttcagcgttt
    39361 tttacacgaa tgatttccat agtgattgct cctttatatt ttggtatagc ccaattatag
    39421 cattcttttt ttctttttac aataattagt atagaccaaa ttgcattttt ttcattttct
    39481 tgacaataaa taggaatccg tgttaggttt cataagatgg ttcaatcaaa caatccatgt
    39541 tgcatgaaaa ccaagcaagt gattcactgt ggacgcttta tgtctgcagt ttttttatga
    39601 aaaaggagtt attatgagta tactgacatt aaacaacatt acccagcaat ttggcgacaa
    39661 aatcctctat gaaggtgtcg atctgcaatt aaatgctggc gaacatcttg ggctgattgg
    39721 acaaaacgga gccggtaaaa gtacattgat taaaatcatc actggtgaga tcttaccaga
    39781 tgacggacag atccattggc aaaaaaatat tcacaaaggt tacctcgatc aatatgtgga
    39841 agtcgatgaa acattaacaa tcgaagaatt tctaaaaact gcgtacgcaa aagaatacga
    39901 aaaggaagaa aaaattgctt ttctttacca aacatatagc gagaccttcg atgattcctt
    39961 gctggaaaaa gctgggaaac tccaaacgga attagaccaa ggagtgtttt atcaaatcga
    40021 caccttagtt gctgagatga gcagcgggtt ggggatcgat gtcttaggtt tagattcact
    40081 gttgaaaaat ctaagtggtg gacaacgttc aaaggtgatt ttagcaaaac tacttttaga
    40141 aaacccagat gttctgatct tagatgaacc aaccaatcac ttagatgatc agcatatcca
    40201 atggctgacg cagtttcttc aggattttga cggtgcgtat atcgtgattt cccatgacca
    40261 agaatttctt gatcagatca ccacccatat cgcagacatc gagtttggaa agattactaa
    40321 gtatactggc catctaaaac aagcattgaa acaaaaggaa caaaatcgcg aaagctattt
    40381 gcgccaatat catgctcaac aaaaacaaat cgaaaagacc gaagcttata ttcgaaaata
    40441 caaagccggt tcccgatcaa cgatggcaaa aagccgacaa aaacaattag ataaaatcga
    40501 acggctgacg cctccagctt cagcaagtaa agctgtcttt gattttccat tctcgcctat
    40561 tgtcacgaca ttagcagtgg aaacaactga tttagtcatc ggatatgatc gaccgctact
    40621 tgcacccatc aatttgacca tccgctttgg tgaaaatatt gccattcgag gcttcaacgg
    40681 gattggaaaa tctactttat taaaaacact gatcggtgag attgaaaaaa taagtggcga
    40741 tttccacttc ccagataaca caaaaatcaa ttacttttca caagatctgt actgggaaaa
    40801 tccattagaa acaccactac aatatttaag cagtcaattt ccaaaagcga ctatcaaaga
    40861 attacgtcgc caactagcta aagcagggtt agttaatcaa ttagcaagtg aacctctcac
    40921 tacattaagt ggtggggaac aaactaaggt gaaacttgca cagttgacaa tgaaccaagg
    40981 taatttactg attctcgatg aaccgacgaa ccatatcgat caagaaacga aagaaagctt
    41041 acaagacggg atacagaaat ttccaggaac agtaatcatc gtctctcatg aacaagaatt
    41101 ttatcaagat cttgtgcaac gagtcattga gattgaacca aaataaacgt ttgattgaat
    41161 agttgaaaaa aaggagctgt gacaaaagtt ttgtcacaac tccttcttct gaataaatgg
    41221 tggccaatta gctgaccttc ggtattagct caaaaaacgg caaaatatga ggagctattt
    41281 ttatttggct attcttatta cttgatgcag aacagctttt cacaacctct tttcgtctat
    41341 tttttatttt cgagatttct ctttccttta aaaacaactg tttgaaagaa gaacgcacat
    41401 ccttgaaaaa caagcccgct aaccgttaca cctaaccagc catactgctg ccacattgtc
    41461 gtccctagca atgaaccagc cgcacctcca ataaagtaca taaacataaa tacagtatta
    41521 tttcggttgc ttgctgcttc acctagccct tgtactcgtg tttgattggc gacttgacca
    41581 aattgattcc cgacgtctaa taaaataata gctaaaagca aaatggccaa atggcttccg
    41641 ccaaccaata aagcaataaa gcttattgtt tgcataacaa gtcccatata cacgattttt
    41701 ctttcagaat aagaatctgc cagtcgtccc acgataggtg cagcaactgc tccagacaaa
    41761 ccaaaaatcg ctaatatccc tgcttcgaat gttccccaat tgtaggcggg actgctgata
    41821 taaaaaatca acgtagacca aaagatcgaa aatgttccaa acatgaaaaa tccactgact
    41881 gccgcttctc ttaatagacg ttgagaagca actaaatgcg gcaaactttt aagtgaatca
    41941 aggtatgaaa cagctgtact actttgctgg acagaacgcg gcattttcca gtaaagcaga
    42001 agtgtaagaa ttccgactgc acataaagca aataaataga tcatccgcca agaaaaaaga
    42061 ctggcaacaa taccagatac cgtccgagaa agcaaaatcc ccacgagtaa accgctaagc
    42121 aatgtaccca tgaccttccc tcttgctttt ggtcccgcta gtaccgcacc gtaaggaatg
    42181 atgatttgcg gcacgatcga aagtaatcct attaaaaaag aagcgcatgc aaataacgta
    42241 aacgaaggcg caaaaaaagc ggccaacaga gagacggcag ataacgctgc cattcgaatg
    42301 atcaattttg gacgatccac cacgtcccct aaaggaacta aaaacagtaa ccctaacgca
    42361 tagcctaatt gggtcaacat cgtcaatatc ccgactgcac ttgtgctaac agataaacta
    42421 gctgctactt ttgttccaat cggctggatg taatacatat tggcaacaac aacgccacaa
    42481 gtgattgata atagtaaaat aagcgaagtt gttaaaggtt ttttttcatt actcttcatt
    42541 gatttccccc atttcctatc ttagtttaca acttatggaa aagattggaa atagaaaaat
    42601 acaactattc gccacactta ttatttgtgc ttttgttttc cttgtttttt cttgcgatct
    42661 ttataaatga agacaactaa ccctactagc acagtaacac ttgcaaccaa cgtgactgca
    42721 gttttgttat atccgtgaaa cagagcttct ccaccacacg catacaacac agacgaaggg
    42781 atgactccaa tcacgatcga caatatgatt tgctgtagag gcaatttcat cgcatctgca
    42841 gcaaaattga ccatagaaga tggaataacc ggtatcatat agcctaacat tacacctatt
    42901 tttggatgtt tcatttgtcg gattgcttgc acccaatgat tcgtttcggt tttcttatct
    42961 aaaaatttta agcgatgcat aaggaaaatt gcagtgatgt taccaagagc attacccaaa
    43021 atgttgatga tcgcacctgt cagtggtcca aagctcaaac cagcaatgac tccaactact
    43081 gaagtaggaa tacctggaac agcacacatc accgctgtca atacgatcaa gagtatcgat
    43141 gcaaaagtcc catgcgaacg aatatgtgcg agtagctctg ccttactcgc tctcggattt
    43201 aaaaataatt ggatgtctgt ctgatattct aaatacaacc gatagcccac taccagtatc
    43261 agaatgattc ccaacgagat caatatcaat cggattattt tctttttcat atttcctcct
    43321 gaaaaaaatc tatattcatt aaataatagt ttaacataaa aacaaaaaag caccgaaatc
    43381 caacatagga tctcagtgct tttaaatagt aaaaattatt taacagttac agatgcgcca
    43441 acttcttcaa gtttagcttt caattcttca gcttcttctt tagatacgcc ttctttaact
    43501 ggtgcaggag cgccatcaac tacagcttta gcttctttca agcctaaacc agttgcttca
    43561 cgaactgctt tgataacttt aactttttgg tctccagctg cagttaattc tacagtgaat
    43621 tctgtttgtt cttcagcagc agcagcgcca ccagcagcag ctacagctac aggagcagca
    43681 gcagatacgc caaattcttc ttcaatagct ttaactaggt cgttaagttc taggatagtt
    43741 gcttctttta actcagcaac gatgttttca atgttcaatg ccattataat ttcctccgtt
    43801 taattgttct tttttattta atgctttatg cggcaattaa gctgcatctc catcttcttt
    43861 gtctgccact gctttgacag cgtaagccac gttgcggact ggcgcttgta gtacagatag
    43921 caacatagat agaagtcctt cgcgatttgg caattttgcc aatgctgtga tttcttccaa
    43981 tgaagagact ttaccttcga tgataccgcc tttgatttct aatgcttttg cttctttagc
    44041 aaattcgtcc atgattttcg ctggtgcgac tacatcttcg ttactgaatg caacagctgt
    44101 aggtccagtg aatacttcgt ccatgccttc aaggccagct tttttagctg cacgtgaaag
    44161 aatagaattt ttgataactt tcatttctac gttagcatca cgaagttgtt tacgtaaacg
    44221 tgttacttca tcaactgtta atccgcggta gtcaacgact actactgatg cagctgctgt
    44281 aaatttttcg cttacttcat caacgattgc tgcttttttt gcgataattg cttcactcat
    44341 ttttgagttt cacctcctga attttgatgg aagagttttt tgcactgaaa aggcaagtca
    44401 cttttatagt tactttgctc aaccagtatt attcatcacc tattcacttc gttcatagtg
    44461 attctactcg ctttgctcga aaggaaactc ctttcgcttt gctcaaccag tattgttcat
    44521 catctcttca cttcgttcat agtgattcac aataaaaaac tctatgccac cgcagacata
    44581 gagggactat tgaatatatt caataaacgt cctcggtagg aaattaaggc ttgatgccac
    44641 ctactgtctt cggtacaagt taattattaa cctcaactag cttagcatgc taaactagtt
    44701 gagtcaagaa ttatttttca gttggatcaa tcaacattct aatatttaat tagaaagaag
    44761 cttggtcaac atggatacca ggtccaaatg ttgttgtgat cgttacattt ttcatgtatt
    44821 gacctttagc tgctgatggt ttagctttta gcaatacatc atggattgct gcaaagtttt
    44881 caactaattt ttcatcgtca aatgaaactt ttccgattgg tacatggata tttccagctt
    44941 tgtccacacg gtaagttact ttaccagctt tcacttcgtt tactgctttt gttacgtcca
    45001 ttgtaactgt accagtttta gggtttggca ttaagccttt tggtcctaat actcgtccta
    45061 gacgacctac agtagccatc atatcaggtg ttgcaacaac tacatcaaag tcaaaccatc
    45121 cgttttggat tttttgaacc atgtcgtcgt cacctacgaa atctgcacca gctgcttcag
    45181 cttcttttgc tttgtctcct ttagcaaaaa ctaaaacagt ttgtgtttta ccagttccgt
    45241 ttggtaatac aacagcacca cggatttgtt ggtctgcttt tttagggtct acgttcaaac
    45301 ggtatgcaac ttcaactgtt gcatcaaatt ttgcaatgtt tgtttctttt gctaaagcta
    45361 ctgcttcggc aacaggataa actttacttg aatcaacttt ttttaatgca tcttgcattt
    45421 ttttgctctt tttagccatt ttggttcctc cttgattgtg gttataacgg ttgtacctcc
    45481 cacgtgttct atatctttca atatagagcc aactgagaag ctgctgtctt agggtgtata
    45541 gattattcta cagtgatccc catgcttcgt gcagttcctt caaccatgcg cattgctgct
    45601 tcaacgttag ctgcgtttag gtcttccatt tttaattcag cgatttctct tacttgatcg
    45661 ctagaaactt tcgcaacttt atttttgttt ggttcgcctg aacctttttc gattttagct
    45721 gcttttttca atagaacagc agctggcggt gtttttgtaa cgaatgtgaa tgaacggtct
    45781 tcgtatacag aaataacaac cggaatgatc aaacctgctt gatcagctgt acgagcgttg
    45841 aattcttttg tgaatcccat gatattgata cccgcttgac ctagtgcagg acctactggt
    45901 ggagctggag ttgctttacc tgcaggaatt tgcaatttaa cgattttttc tactttcttt
    45961 gccacgagac atacctcctt aagtccgtga tgtggttaat tggagatgca tatttctcct
    46021 cccacgtttt atctgatctg aaaaaatcca gacaaataat gtgcaaaaca atgcacactg
    46081 gtacagtata gcaaatttat ttgttttttc aagatttttt tctgctattt ttacattttg
    46141 cttgaataaa cgctaaattt attctaaaaa aacaacaatt tttcgttctc atttcttctt
    46201 ttatgttaca cttgcgctag catggttcaa cagatgaaag caaacaataa cacggttttt
    46261 tagacccttg tacaaagatt cctacataac aaaatgaggt ggagaaaatg aaagatttaa
    46321 ggtatagaag tgtctttgat attattggac ctgtgatgat tggtccaagt agctctcaca
    46381 ctgccggagc tgctagaatc gggaaaatca tacgtagtat atttggcgaa cagcctgatt
    46441 ctgtagatat ttatctatat gaatcatttg caaaaaccta tcgggggcac ggaacagata
    46501 ttgcattagt tggcggcctg ttagggatgg aacccgatga tgaacgttta gctgattctt
    46561 tgaaattggc atatgaagcc ggtatggaag tcttgtttgt tcctaagagt gaaaaagccg
    46621 aacatccaaa ctctgtaaag atgcttctaa aaaaaggaac acgaaagctt tcagtcactg
    46681 gcatttcgat cggcggtggc aatatccaga tttctgaatt gaatggattc aaaatttctt
    46741 taagcatggg tactcctacc ttgatcgttg tccaccaaga tgttccaggt atgattgcta
    46801 aagtgactag tatactttct gagaccaata cgaatatcgg cactatgaca gtgacacggg
    46861 aatcaaaagg tgaaaatgcc attatgataa ttgaagtaga tgatcctcaa gtagaagaaa
    46921 cggtaaaaag actcaaacag ctgccaaata tcgacagcgt aaattatttc gattaaggag
    46981 ctaaaaaaat gtttttatcg attgaagaat tagtagatca agcaaaagct tatccaagtg
    47041 tagcagaatt gatgattgca gttgaaatgg aaatgagtgg ccgttcccgt agtcacatca
    47101 tcgagatcat ggaaaaaaac ctctcagtaa tggaacaatc aatcaacgag ggaaaagaag
    47161 gtgttacctc cgtcacagga attaccggtg gtgatgcaaa aaaattagat gattatttaa
    47221 atgaggcaga ctttttaagt ggagaaacaa tcttaaaagc tgtacgcaat gctgtagctg
    47281 ttaatgaagt caatgcaaaa atggggttga tttgtgctac accgactgcc ggaagcgcgg
    47341 gtgttgttcc tggtgtgctg atggctgtcc gagatcggct tgatttgaca catgaacagc
    47401 aattggaatt cttatttacc gctggcgctt tcgggttagt catcgcaaac aacgcttcta
    47461 tcagtggtgc agaaggggga tgtcaagcag aagttggttc tgcaagtgca atggcagcag
    47521 cagctttggt ttgtgcaaaa aatgggactc ctcatcaagc agcacaagca gtagccatta
    47581 cattgaaaaa tatgatggga ctgatttgcg atcccgttgc aggcttagtt gaagtcccgt
    47641 gtgtcaaacg taatgcttta ggctcttctc aagcttttat ctctgctgat atggcattag
    47701 cgggtatcga aagtgtcatt ccgccggatg aagtcgttgc tgcaatgtac caagtcggac
    47761 gtcaaatgcc gtcgattttc aaagaaacag cagaaggtgg cttagctgtt acgccaactg
    47821 ctaaacgact tgcggaagag attttaaata agagggcgtg ataaagctcc ttaatttcga
    47881 gtattaagag attagttatc ttcataacaa aaaacgaaga gaggactaat tgcccttctc
    47941 ttcgtttttt attaatccat caatttcgta ttttttactt catcgatcgt ttttgttcct
    48001 gcaagttgca tcgtgatcga caattctttg ttcaggtgtt caaaaacaga tgttactcct
    48061 tctgccccac ctagattcaa cccataaatc actggtcggc caatcgcaac taagtcagca
    48121 ccacttgcca gagctttgaa gacatgctct cctcgacgga caccagagtc gaaaatcact
    48181 ggtacacgtt tgttgactac ttcggcaatt tttggcaata cttcaaagga cgcaggacct
    48241 ccatctagtt gacgtccacc atgattggat acccagatac catctgcccc tgcagagata
    48301 gcgattactg catcttctgg cgattgtatt ccttttacga taactggaag atgggtgatt
    48361 tctttgattg ttttgatgtc atctggtgtc aagccttgtt ttgcagctgc ataaatttct
    48421 gcgattcctt ttccttcgcc attaccactt gcactttgtt cgctatacgc agctaagtta
    48481 ggcattggta atggaaattg gaattgattg atgacgtctt cttcacggta accaccgagc
    48541 gttgaatctg ccgttaaaat gatagcttta gcccctgctt ctactgcttt gttcaaaatg
    48601 aactcattga atctgtcgtc tttactcata tataattgga aaaactgcgg tgcgcctggc
    48661 gctgcatcgg ctgcgtcttt gattgtcgta tttgcataag tgctgatgga aaagattgat
    48721 ccagcagcag ctactccttt agctgtatca gcttcccctt tttcatgtgc caatccttgg
    48781 gccgctgatg gcgcttggat aatcggtgta tctaattcaa ttccgaaaac agatgtatgc
    48841 aaatcggctg agtcgattcc gcgtaatatc cgtggcatga ttttctttgt attaaaagaa
    48901 gtcgtatttt ctttcatcgt ccactcatct tcagaaccac cgcgaatata gccaaaagct
    48961 cctgcttcca tgcgctcttt tacacgacct tctagttagg caatgtttac aatatcgatt
    49021 ggatgttctt cattacttgt atgataagtc atagtagatc cttctttcat cttcttgatt
    49081 acatataaat catactaaac ttacaaaaag taagcaaaca tttactctca gatactttta
    49141 tcgctattct ttccaaataa atcgacttac aagctgatct acttcttggt tttcatgaag
    49201 catactatga gaggcatttt cacctgtcac tactttttcc tctatttcat ttccgcgttg
    49261 cttcaacaac gcatagaccg ctaatgcact gtttaacggt actgttccat cactcaagtc
    49321 tgtttcatct agttgaccag caatcaagaa aaatcgagtg gttataggaa tattaccgat
    49381 catttgctgg taatcttgat agcggttaga aacgacagca ggcccctttg ctaactcatc
    49441 tgtcagagac tgcgcactat catcgacaaa atcattaaaa ggcgcgccaa ttgctgttaa
    49501 tgtctgaact tgtggcaatg acgtatcctg tccatacgtt cctaaatagc gtagtgcact
    49561 aactcctccc atggaatgcc ccactatgtt gactttatct atgccgtagt tttctttcag
    49621 atacaaaaga caagttttga tccattctgc ttgattccac tcgttatttt tattatcttc
    49681 aaacaatact tggaccatcg gattgtctgc ttttccagac aaatctcctg ttgcttgtat
    49741 ttgtccatct gttcctactg ttaaaaccaa ttcttttact gcttgctgat ttttttccaa
    49801 acgccgcaac atccctttaa aggaattttc tgtcccgctg tagccgtgga aaaaaagtgt
    49861 tggaatagtg gttttttcta tcactttact ggattctgcc gttttttctt tatcagaaac
    49921 ttcagtagta tttatcttcg tcgtctggca accacttaac gcaaacaaac tgataaggac
    49981 taaagctgct gcagttgcac gtttgcataa atttttgatt ggttctgtca tacacctctt
    50041 cctttccata tagaaaaaag aaagacttga aaggccaatc atatgatcga catttcaagt
    50101 ctctttatta atcgatttta tctacttgat cgaaatcaag ttctgtactg gtttcacgtc
    50161 caaacatatc gatgttgact ttcaattttt ctttttctcc gtcaacttct gttacttgtc
    50221 cttctaatcc agcaaatgcg ccttcgatga ttttcacgac ttcgccaact tctacttcta
    50281 gatcattttg tcgcaggctc ataccgatag aacgcaagat atgattgact tcttctggaa
    50341 gtaatggtgc tggtttgctt ccggctccgt gtgaaccaac gaatcctgtc acaccaggtg
    50401 tgttgcggac aacataccat gaagcgtctg tcatgatcat ttcaacaagt acgtatcctg
    50461 ggaatgtttt atgaacgatt tctttttctt tcccattttt gacttcagtt tctttttctt
    50521 caggaacaac gacacggaaa ataaagtcgg ccattttcat actttgcgca cgagattcga
    50581 tatttgcttt tactttgttt tcatatcctg aatatgtatg caagacatac cagttttttt
    50641 caaaagattc cattgaaggc tcctcatttc attgtaaaat aaaaaaacct cagtacaccc
    50701 gaagtttttc tttcgcttca ttatagcact aaaagtacgt tgtggctagc gagttatttt
    50761 aaaatccagc caaataagct ttggatggct gtatccatta cgtaaaacat caatccgaaa
    50821 ataatagaag tttcgatgac tactaacgta tctttacgga gttgttttct gcttggccaa
    50881 gttacttgtt tgatttcatc ttttacgctt tttagaaatt tcatgagaca acctcccttg
    50941 ctactgttta tttcgtttct ttatgtaatg tatattgatt acaatattta caaaacttat
    51001 tgatttccaa acgttcgccg ctttttcctt cactgactga ttttgtgtag ttgcgagacc
    51061 cacaaacgga acaagcgagt gctgcttttt tctttgccat ttacttctgc ccccttgctg
    51121 agaatcagac ttatacttca taacagtatc acgtaacttt ttacttgtca atttgtgaaa
    51181 taaactatct attgttttgg ataaaattat gatatgatta atttgaaatt aagctaaaat
    51241 gagacaattg gaggtatagc gatgctatta aaaacacttg tatataagaa aaaagatctg
    51301 acaaccgtta cagagactag tacattagaa gaagcattaa aaattttaga aacttccgga
    51361 taccgttgtg tgccgatctt agattcttca ggtaatattt tccgtggaaa catttacaaa
    51421 atgcatatct atcgtcataa agcaaatggc ggtgatatga cgcttcctgt cactcatctt
    51481 ttgaaaaacg ctacaaagtt catttacctg gatacttctt tcttcaaagt attctttacg
    51541 atcaaagagc ttccttatat tgctgtcctt gacagtgaaa atcattttta tggtattttg
    51601 acacatagta cgttgcttaa tatgctctct caatcttgga gcgtagaaca aggaagctat
    51661 gtactgacaa ttgcttccac aggaaagcaa ggagatttgg ctgctattgc aaaaatcatt
    51721 tcaaaacaca gcagcattgc cagctgtatt actcttgata tcgaaaaaga cgaatacatt
    51781 cgacgtacat tgatcacgct accggctaac actgaagcga aagtatgtga aacgatcgtc
    51841 aaccacttag agaaaaagaa ttataaagtg gtagaaattg aaaatttgca aaaccaagaa
    51901 gcataatcaa aaagcgaaaa aagaaaacag ctaatctgct ttcttttttc gctttttata
    51961 attagacacg cttttcaaaa tcaagcgcgc gatctaaata atacatcaat ggtgctgaaa
    52021 cagccatgac gataaactca cttaatgcaa gcgtgccata ggttgtccaa aatgcttggc
    52081 cacctgttgg aactaacata taagcaatca gtcccatgct gatggtaaag aagatcgtgt
    52141 tcaatactaa acgcatcttt acatttttca ctttgttttg caataaagct gtcaggccta
    52201 aagaaagcaa tgtttggccg ccaccaaaaa ccacatccat gataccaaaa ccaaagaagg
    52261 cattatagac gatgaccccg cctaaaactc cccaaagcaa tttacggtta aagacaacta
    52321 aatgattcaa actttctgaa atacgaaact ggatcggccc tgaggataca ggcgcaacta
    52381 aaatagttaa cgctagataa agagccatga tgatgccatt tacaacgatt acggataacc
    52441 gttgtctgct tttcgttttt tgcattttct ctcctctttt ctcctagttt ttttaacgcg
    52501 ggatggttga tgaaccgcgg ttatgtgaaa caaacaataa ttataacaga cttttcattt
    52561 atttcaatcc gtcttatctg cttttaaaaa agcaaaagct taaacaatgt aaacgtttgc
    52621 taaaaatcgt gggatatggt ataaagtaag tgtaaggggt cataagaatt cccagtaaag
    52681 cagacgaagt aggatctgca agaacagaat tgttgtgaaa cttaaataaa taaaaaagga
    52741 tgtgggaatt tgagcaacct cttactagag aacggtctag caagcagctg aagatctaag
    52801 tggacatgcc gaaccttgga acttctcctt acgtaagtaa tggatcatgc gcttgctagg
    52861 cttttttgtg tttttcggtc ttcggacctt tttcattttc ctagacttct gctataataa
    52921 ccaagaatta attttgtaac agattttttt gaaaaaacaa gtttctttca ttcaaaaaat
    52981 agaaaaagct tgctaattat tggttaacca gcaaacagga gtattaaaat atcttgtttt
    53041 attgaatagc aggaggaaat catgaaattc cattatcata tattgatcaa tccatcggca
    53101 ggcagcggaa atggctataa agtagcagaa agaattttac cggtattaaa aaataagcat
    53161 attgactata cacttcatta tagtgaatac aaaggacacg atgctgagat tgctgaaact
    53221 ttggcaaaag aaacattgat tccttggata gaagaagaac agaaaacaat cgatactttc
    53281 ccccttttga tcatcgtagg aggtgacggc accttacatc aggtacttga tactttctat
    53341 cagatggaag tagaattccc agttgcttat attccagcag gttctggaga tgattttgct
    53401 cgaggggcag gccttccaaa aaatcccaaa aaaggacttc agctgatttt agcagctcaa
    53461 tcaccagaaa aagtccacat aatggcttat gaagaaaaaa taagtgaaaa aaaaggaata
    53521 gctgttaata atttcggtat aggattagat gcagctatcg tccatgcgac aaatcattct
    53581 tccacaaaaa agcgattgaa caaatacaac ttaggatcat tttcgtattt attctctatt
    53641 ctccgtgctt tattcactca aaaaggattt ccaattctgg tagatgcagg aggaaaacaa
    53701 ttaagttttt caaacgcatt tttatgtaca gcaacgaagc atcctttttt tggcggagga
    53761 atcgcgattg ttccaactgc tgatgcgtct aaaccagtca ttgattttgt cgtggtcgaa
    53821 cgaatcaatt tctttaaaat cttgtggctc attcttttac ttatacagaa aaaacaattg
    53881 aaatcgaaat atttccatca ctacacaaca aacagattac gtatcgtttc aacaacaccg
    53941 caacatggtc aagaagatgg agaagaaatg gaaaaacgac cttttgatat cacaataacc
    54001 acaactaaac agttgttttg gtgttaataa aagaggtttt gtcagaagct acatctggaa
    54061 caccgtttat tcggaaaaaa ggactgtgac acgacttttg tcacagtcct ttttttacta
    54121 tgcagttaat tctttgccca attgggttgc catcgatagt ttctttcttt acccaaaata
    54181 aattggatca ttgaaaacac cgcagcaaaa gcaactaaga cacaaccatt gaaccaaaaa
    54241 gattctgcaa atgtttgatt gtaactgagt gtttcactga tcaagttatt attttgaaca
    54301 aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca tttctggcaa gtattctgct
    54361 ggtacaaaca ccccaccgat aaagcaactg cctgtgataa aaatatcttt gatcccaccg
    54421 ctggtttctg agttttttac caatgaagtg atacaagccg aaaagctaat gatcggcaat
    54481 aaaaacaaga aagtatttaa aatatgatac cataccgtta tatcccacga ggtgtggatc
    54541 actaacagaa ccattagaag taagaagcca ctgaacaaca gcagcgagta actaatcaaa
    54601 ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg gcgcactctg gtttcgttta
    54661 ctgatctctt tgcgattaaa tgctagattg atgacgctga aaccgctaaa aatggataga
    54721 aacaacccat aagacaagaa attaaaggtt gtgcccgtca acagcttttt catccgctga
    54781 ctatatcccg cacttagctc aacttctcca gtaaccgaga gtgccatttg tgtctgttcc
    54841 atagctgcat cgattgtttt atcttcttct tgaaacagaa tcagtgtttg caaaaaggtg
    54901 ttcacttgct gtgtaacaac tgttttagaa aaggcatctg ggcgactctg tatcttgatc
    54961 gtcggcatct ttcctacttc gacttgttcg gtaaagtctg caggcagatg taagataatg
    55021 tttacacgat taaaataaag agcatcatcg atttcttttt gtgaggttcc atccaatgta
    55081 acgactgttt ccttgtcatt caaatattta cgaaggccat cgactacagg cgactcttct
    55141 tcactaatca aggcgatttt cgcatcttgc agagaggtat tttcaacatc aatattttgc
    55201 gcaaaaaaga atgtggcaac aacagtgata attacaccta tcagtaaatt cgatttattt
    55261 gctttaagca atgtccaaat cgttttataa agcgtcataa cgcacccctc tttccatcca
    55321 agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac catagaagat tggtataaaa
    55381 actagccaaa tcagtgtaga aataaagttt atacaaactt tcgctgatca agttgacgag
    55441 atttaattga ccaacaatcg gaatatgaag atcaatccaa tacttcactt gttccgaccc
    55501 catcatacca gcaaaaaagc tcatcgcaat cgtcactgaa atcaagatgc tatccttttg
    55561 caccagattc atttttggta tcaaattacc aaccaatgta cctaacaaaa tcgcacacaa
    55621 cgaccccaga gcggtaacaa tcatcaacca ttgccaacgt tcaccaaagt ctacttgata
    55681 gataaaacga aagacagcta acataatata aatctctgtc aaaacaatcg taaagcttgc
    55741 tgccaaatta gcgattgaaa ctaacgattg ctttctagga atcaaggaca agcgaatacc
    55801 atttgacgat tgatttgctt gctgatcctg tacattgcgg accccccaca tcgtcccgta
    55861 gagaatcgcc attccaatca gagtgaagaa ataaaaactt ttgaaactca tattacgacc
    55921 tgcatgaact tcttgaaaag atacttcttg ttcaaaaaca gtcatgatgg gcgcgagatc
    55981 aacgttctcc acttctgcca ctttactcga aattatacca atacgctgta aaaattgatc
    56041 catgacgttt ttcatcaacg tctgactcat tcctgcttga cccacatgga gcgaaacaga
    56101 tgaaccatca atgagataaa aaccagccaa atcatctgca tttagctttt cattcgcttc
    56161 tacttccgat agttcctgta cttcaaataa tggtttatca ttgacttcga cttgttctaa
    56221 gactgtggta aaattttccg aaagcgctgt ttgatccgct ttgattacaa ttccagtatt
    56281 aatcgtttcg agattgccac cttgatcaat ctcgccaaag gccgccataa acatcaatcc
    56341 taaaagaatt ggaaaggcca atgtccaaaa caacatggat ttatttcgca gcagtatttt
    56401 tgtgcgatat ttataaaaat gccaaaacat tatttcccct cctctagtct ctcaaatcct
    56461 tgccagtaat ctctaaaaag acatcattca aggacgcttc tttggttgct atttttccgt
    56521 aactgatctt ttcttcttgt aagattgtaa gaatcggcaa caatactgta tttagttcag
    56581 tagttgttac ttggagctga ccttttttat aagcgattcc atcagaagct attgttcgct
    56641 gacaacacgt tttctgggag taatgggatg tcgatcgtca aacgatccgc cgtccgtacc
    56701 atatctttta gagattcttt ggttccttta gcaatcacct gtccttgatc catgatcacg
    56761 atctggtcgc aaagaatttc tacttcttcc atgtaatgtg ttgtatagac aatggttgct
    56821 ccttgtcgat tcagctcctt gatactttct aaaattttat tccgactttg ggggtctaca
    56881 gctactgtcg gctcatctaa aaaaattaac cgcggcttgt gggcaatccc acatgcgatg
    56941 ttcaaccgac gtttcaagcc accactaagt tctcctggac gaaacgaaac atatttttct
    57001 aatcccacta attgaatcac ctcttcaatc aaggctttcc ttttctcttt ttcggaaaca
    57061 tataaaccgc aaaaataatc gatattttct tgcacactta gttcgtcaaa gaccgcaacg
    57121 tcttgaggaa cgaccccaat cattgccttg acagcataat tttcaggagt cattgttgtc
    57181 ccgaacaatt taatggttcc tttgtcataa tttaacaaag aaagcataca gttgatggca
    57241 gtcgatttcc cactgccgtt tggtcctaac agacctaaga cttctccttc ttgtacttgc
    57301 agatcaaaat gattcaatgc tacaaaatct ccatagcgtt tgactaattt atcaatttcg
    57361 ataatcatca tgaaaaactc cttccaaatt tcttgttgat ctgactataa taaagtgcaa
    57421 gaaaagaaac tagtgacgat tggctaaacc acacatgaca tttgtcacaa tgaaggagtc
    57481 tgctatgcat aaatctcggc tactcaacga aactagcttt ctactggtta tctcattgct
    57541 tttgctggta agtcaaggat tcgttgctat gcaagttatc tatttattga tcgccgtttt
    57601 attcactggt gtcagttatt tactgcctac aaagccaaat tggattttcc aagttattct
    57661 atttctttta tgtgcctttt tacctgatct tgtcctgttt ctgccagcga cgatgcgagt
    57721 gatcgcccct gaagaaagcc accttgatta cttgtttttg ttaggttttt tgttgatttc
    57781 gacggttggt aatcatcccc ccatcaaggt cgcctttgtc gtaattttgc tgtttttttc
    57841 cttttactta cgaaaaaaag atcaacgaac gaccgatctt gagaaaaagt acattgtctc
    57901 caaagatact cattgggaaa aacaacaaga gttatcggaa caaaataaag cattggccct
    57961 gtcacaagaa acacaattag ccttgcaaat tgtggaagaa cggaaccgaa ttgcccgaga
    58021 catccatgac aatgtcggtc atctgctgtc aagtgcgatt ttacaaattg gtgcgcttga
    58081 aatgatcaat caagaaccaa aactaaaaga accattagaa aatttaagtg ccaccgttca
    58141 cactgggatg gatcggattc gtcaaagtgt ccatgacctc catgagacat cgatctcttt
    58201 tcaacactcc ttagagtttc tgatcgctga ttttccttct tctgttacga ttgaaggaaa
    58261 cttgtttgaa ggattgaatg aaacgcagca aaactgcttc ttaatggtca tcaaagaagc
    58321 cttaaccaac agtatcaaac atagtcatgc caaaaccgtt gttttacatt ttcgaacgtt
    58381 gccggccttt tatcgcttgc aaatcacgaa tgatggcacc agcccacaaa aaaattctgc
    58441 tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa gaacaaaagg gacaagtcca
    58501 tattttccaa gaaaaccagc aatttcagtt aacgatcatt ttaccaaggg agggacacca
    58561 atgataacag tagtcattat tgagatgatc catttgtgac gaaatcgtta caaaccattt
    58621 tagaaagcac gaaagagatc cgtgtgttag gcattggtca ttgtgccaag gatgcgctag
    58681 tcttatacga aacccatcgt cccgatgttt tgctgacgga catccgcatg cctaaacaaa
    58741 cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc cttttgcttt
    58801 tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt gtcaaagggt
    58861 atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct tataatggac
    58921 aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag aataaaccga
    58981 cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc atcaaagaag
    59041 tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt gacggcactg
    59101 ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc acgcaattgg
    59161 ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa cctgaatgat
    59221 gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc gcaaaccatt
    59281 tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg gattgttcgg
    59341 cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg attcttcacg
    59401 atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca tctcatctaa
    59461 ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt cggtttcttt
    59521 agccataaag taacgccccc cttttgattt cagcttagca tatcacactg aaaaaacaaa
    59581 agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc aagcattttt
    59641 tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat ctactaactg
    59701 gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt ctacctcttc
    59761 tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt ccattacttg
    59821 gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt ttacaacccg
    59881 tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag aatcttcata
    59941 agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga tccttgattt
    60001 caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg cttgctcttc
    60061 ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca aattacgctg
    60121 aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt cactgccttg
    60181 tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt ttcttttata
    60241 agtgacctca tttgcatcaa actggataac taattcatcc actttatctt cagaatcttt
    60301 tgccaagatg atacccgtga tttctcccat atctccattg aatacattca attcgggagt
    60361 attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc aatgtacttc
    60421 cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta acgcatcgat
    60481 ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac ggaatccctt
    60541 atttttcgct ttttccacaa ttttagagat caagggttca atttgataag catcacttcg
    60601 gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc cttctttgat
    60661 ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct gattgagttc
    60721 cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag gaccgacaga
    60781 gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa tcgctttgaa
    60841 taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca aaagtccgcc
    60901 ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc ccagaagacg
    60961 atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg ctcggccagt
    61021 tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat ccaattccag
    61081 tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt tccccgtacc
    61141 tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag cttgttcttg
    61201 cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct tctgcacttc
    61261 tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg aattaccgat
    61321 cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt gttgtatctt
    61381 tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga tttcaattgg
    61441 gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg gtacgtatgt
    61501 atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc gaattcttct
    61561 cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt tgaacccgat
    61621 tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca aagactcgtt
    61681 cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac gattcagtcc
    61741 catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca tttctctttt
    61801 tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga ttttttcgat
    61861 agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga ttcctgggaa
    61921 tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt cttgctcata
    61981 tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc cataaaaacg
    62041 ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct ctttttcacg
    62101 gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat tactaggatt
    62161 ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg gctgcatcgg
    62221 aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct aaaaaatctg
    62281 tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca gtctctaaaa
    62341 tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc tcttttcctg
    62401 tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa agtgggccat
    62461 ctttatgttg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt gccgattcaa
    62521 tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc aaattcggca
    62581 gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa gtacccagcc
    62641 ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc tctttgttga
    62701 taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct ttaaaaggaa
    62761 catattttac ctttttccca aatgctttga tttcttcgta actttgtggc aaaagcggag
    62821 aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc ccatgtcggg
    62881 taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact ctataataaa
    62941 ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta gggaatcctt
    63001 gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc aatgagcgga
    63061 catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc ataaatgttt
    63121 ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca tcagcaaaat
    63181 tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta cgattaccta
    63241 aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca ttccaataat
    63301 ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc tcgattaaat
    63361 gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt gcagggatta
    63421 atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt atgttcgttt
    63481 ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg tgtcagtcac
    63541 tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca ggaacctgat
    63601 aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt ttttgcaacc
    63661 tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa taattctatg
    63721 tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg ctcttctacc
    63781 tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg tatctcaaat
    63841 tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt ggctactaca
    63901 cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg acgtagttcc
    63961 tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga gagtacacgt
    64021 tggaattctt ggtaatgaga aggcgaaaag atatttaaaa cctcgttgaa tgtttgatca
    64081 gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga ttgttctgta
    64141 gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat ctttttcaat
    64201 tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag cgagacttct
    64261 tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga ttggatcatt
    64321 ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg ggataaaaaa
    64381 taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat caagccatta
    64441 tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg attttctgcc
    64501 aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt ctgttttatc
    64561 ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc tagaagaaag
    64621 tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac tacacatcta
    64681 ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac ttagcggtcg
    64741 gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct ggggaaaaag
    64801 atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat aacgatatcg
    64861 aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg gatggcgtag
    64921 tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa ctattgatcg
    64981 aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt cctgaagatc
    65041 ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc ttgactcatg
    65101 gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa ttgattgcct
    65161 atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag aatgcagcac
    65221 atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg gatcttcagt
    65281 tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc aaatgttttt
    65341 gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa tcagtacact
    65401 cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat caaatcctag
    65461 acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga ttgcaaatag
    65521 catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac ctacgattag
    65581 aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt cagccaaaac
    65641 aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa cagccacagc
    65701 tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga agactgctaa
    65761 aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg tcgacatacc
    65821 taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta ctggattttc
    65881 attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag cttcatcatc
    65941 aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat cataatcggt
    66001 aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt cttggtcgtc
    66061 gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg cgtcgtcatc
    66121 attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt gattaacgac
    66181 atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt acatcgcaga
    66241 gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg cgccagccgt
    66301 ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg acatcaaact
    66361 taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag cattatctgt
    66421 atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta ggtattcttt
    66481 catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt taggcgacag
    66541 ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt gcccctgctc
    66601 atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt cccttaaatc
    66661 ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac caatctcacc
    66721 tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa aggctgcttg
    66781 aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca atgaagggct
    66841 tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag cagggcacag
    66901 ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag ctggatatca
    66961 actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc cgaacgtcct
    67021 tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg caaatcgata
    67081 tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata ttttttcaca
    67141 aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg ctttgcaaaa
    67201 agcatcaaac cagatgtatc ccgatctagt cgcgtcacca catggattac ttggttttcg
    67261 taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt tggatggtat
    67321 tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg ttcatcttca
    67381 tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc ttcagcagga
    67441 atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc tacttgatca
    67501 ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt tgagatccct
    67561 ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc ccatgtaaac
    67621 tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat gcatatgtcg
    67681 ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc ggatatttgc
    67741 ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt ccaattttat
    67801 ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa acactcgatt
    67861 attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga tcacagcacc
    67921 gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca atccatctcc
    67981 tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg tacgattggc
    68041 ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt catccaaata
    68101 actgatccga acatccagca agggataact aacactttgt tcccggttcg ttcgtaagct
    68161 gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta aatgacctgt
    68221 atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga acgccgacaa
    68281 taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat ctcgttgaat
    68341 ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct ttgcttcttt
    68401 attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct ttcttcaaaa
    68461 gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac cgctgtgctt
    68521 cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca gcttctgccg
    68581 cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta taattcagcg
    68641 aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt tccgccaaaa
    68701 ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga taagaacggt
    68761 agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc atgtcttttc
    68821 ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac atgatcctta
    68881 acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc cgtaattgtg
    68941 attttgttac aatactatcg actggcttga ctctcccagt gacaaattca atcgggacat
    69001 gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc aattctgata
    69061 cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct gatacctcta
    69121 cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt actcttgatt
    69181 tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc gatcaaatga
    69241 cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac gagatattca
    69301 tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt tatttcgata
    69361 ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc gttggtcatc
    69421 aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca acggatacct
    69481 ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt tcaggcgcag
    69541 tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa accggaaagc
    69601 ttacaacaaa acgggctgaa ttccctattg aagaaggact tttagctatt gatgaaagct
    69661 ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca tctgtgggaa
    69721 aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct gctaagaaca
    69781 agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca aggcacttga
    69841 gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta gtcactagtt
    69901 gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt gttaatcctt
    69961 taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa gaagagtacg
    70021 ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat ttgcagacaa
    70081 ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa cgtaatcact
    70141 tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt caaggaaaga
    70201 aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat gacataccat
    70261 attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg aatatgttta
    70321 aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa aaaattgctc
    70381 gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc tgcgaccgtg
    70441 attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc acagagctgt
    70501 gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat acaaatgatt
    70561 ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaaa aatacgtcga
    70621 ctcccttaca agagagccga cgtatttttt tcgtttctat tcgagaaaat caaaaataga
    70681 aagccttata aacgatcgat caattcttct aattcattta gacgttgttc aaacatcgac
    70741 attgcatctt caatatatgc agcctgtgtc atatcaactc ctgctttttt cattacttcc
    70801 acaggataat cgctgttacc tgcttttagg taagccaagt agttctctag tgcctctggt
    70861 tcctggttta gtattttctt cgccagtgct gaagcagcag aaaagccagt cgagtattgg
    70921 aaaacatagt aattataata aaaatgcggt atccgtgacc attcgaattt aatttctggg
    70981 tcttcttcga ctgctggacc ataatatttt gcattcaatt taccataact atcacttagg
    71041 tattcactag tcaatggcac acctttttca tcttccgtat gcatgaaatg ctcgaattca
    71101 gcgaattgtg tctggcggaa aactgttcct ttaaacccat ccaagtaatg gttgagtaca
    71161 taagcccgta cacgagggtc tttttctgtt tccaataaat actccgttag gatattttca
    71221 ttcgttgtcg aagcaatttc tgctaaaaag atggagtagt cgccgtacac ataaggctgg
    71281 ttcgaacgag tgaaataact atgaacacta tgtcccattt cgtggacaag cgtaaatagc
    71341 tgatccagcg tatcatgcca attcaataaa atatatggat ttgtgtcata gcttcccgaa
    71401 gaataagcat cgcttcgttt ccctttattt tcgacaacat cgatccaacg ttcagagaat
    71461 gctttttcta cgatggccat gtattcttca cccattggtt tcagtgcttc taaagctttt
    71521 tcttttgctt cttcgtacgt aaaggtaatt ggagcttccc ctaagaccgg tgtataaaga
    71581 tcatacatgt gcagtttttc cacttctaat aaacgtttcc gtaattccat gtatcgatgt
    71641 aacaaaggca aatgcttgtt taccacgtct accaaagtat cgtatacact ttcaggaata
    71701 tgattattgc tcaaagacgc ttctctggca gagctgtaat tacggacttt cgctttaaaa
    71761 ttatgtcctt ttatatgtgt gcctaaagta gaagcaaatg tatttctaaa ttgttcgtaa
    71821 acactgtaca atcccttaaa tgctgcttcg cgcacccttc gatccgtgct ttctagcaac
    71881 tgaccataca cgccatgaga taattggact atttcaccat tttctccttc aatcgttgga
    71941 aaaactagat ctgcattatt caaaacagca aatgtatcac ttgaagcatc aaagatttca
    72001 cctgctccag caagaagaga ttcctgctca gcagataaga catgggctcg attatctact
    72061 atttgctgga tataatggcg atagacttcc aattttggtt cttctttgaa atattgccaa
    72121 atctggtcat ctgacaattg caatatttct ggttcaaacc aggaaacggc ttcactaact
    72181 ttcgaaaaca gactgcttgc tcttgcataa agcgcttggt aatctgtatt tccagtgtct
    72241 tgatcgtttt taaggtgcgc atatacataa atgacttcag tttggcgata aaccctcaat
    72301 acgaattcaa tcgcatttaa aaattgagaa gcgccttgat caagtgttcc tttgtgtttt
    72361 tcagattgtt ttaactcttc tgataattcc aaatatttct catcaaactc ttggtcgctt
    72421 gaaaagatct tggtcaagtc ccaagttaaa ttttcaggca attcttctcg ttttggcaac
    72481 tgctttactt ccatgaaatc cactcctttt cttcccttag ctctatctat caaaatagat
    72541 catagtctaa catccacatg tcacagcatc taacttttct actcattcat gtgtctgctt
    72601 ccatcaattt tagcataact aaatcttgtt ttacatagaa aaccgattcc tagcctattt
    72661 ttatacttac tattttttca aagaagacaa gtgtatgcat tcgttaaaaa actgctgata
    72721 gaccatctct tcatcaatca taggaaaaag ccattccctt ttatgttctt ttatttggca
    72781 aagccatgag ttgaaatcag gaactttctg gttttccaag gcttcttcgt acaacattcg
    72841 ataaagaaaa acctgttctt gtaaataaaa gaaaaaccga cttttttgat agatccacga
    72901 tgatagatgc aaaagatgtt tatgacgcaa gtagcattgt tcttgtatgg atactgtatt
    72961 cttttgcttg tgaataagtt ggcgtgtcag ccatttcttc ccatcttcac tcactttttc
    73021 tatttttttc atttggttca ttttaatttc gttactagtg aatatttctt taaggtccct
    73081 actagaaaaa gtccagcagc tactgcaaaa ggaaatatgc cctgatacag tctctgtaat
    73141 atgatgatac aaataaagct tttgtttctt gagatcagct ttccagcaat gcactcctct
    73201 ttttctatta tagtagcagc aacttttttc tatcaatgag aattgcgatt gtccaagaaa
    73261 agaattacca agtatccacc atacttggta actgttattc aaataatttt gggttctttc
    73321 aataaatctc tggtgagaca gtctagaaca ttggatttct attgctagat tcgccaacaa
    73381 aatatccggc ctttgccgca acctcggcaa ataggcttcc aaaaatactg gttctactga
    73441 ctgtcccagc caatccatga agcattcctt taactgtaag tgctcttttg attctctttc
    73501 actaaagacc gaacagttat ctgatttttg atgggcaaaa tgagcacatt ttttctttcc
    73561 ctttttcaaa atcactcttt ttcgacagcc acgacaataa tatttctttc ctttttctgc
    73621 atgtttagca aaacagcact tattatattc attcattgca agcagcattt ttctccctct
    73681 gaacttattt acgtctaaga atttatttac acgaaaaaag agggcgtgaa aaagctattc
    73741 tgcatcaagt aataagaaca gctaaacaaa aatagttccc aatatttttc gtttggttgg
    73801 gcttgttacc gcagatgcaa gcttttgaac acatttatac gaaaaaaaga ctgcgacaca
    73861 atttttgtca cagtctctta ctataatgct gatttataca aaataaaatt tcgttcgctc
    73921 gatagcatta cgcgccatca gacattgtcc atattcattc aatgtttctg gtgtacgatc
    73981 gctcttttca gcaaactcca aaattcgagc aatctgattc tctacatccg cttggttgag
    74041 attttccatc cagaagtgaa cgactaggta atagcgctct tcgaataaat acaaatcagt
    74101 ccaagcagac tctagttcga catctgttgc aagttggatc acttgttcaa aatcttcaaa
    74161 agcaaaagtt gcttgtcttt cctgttcttc tagggcgctt ccagataatt cttcctccgg
    74221 atcgctgcca ataatctgct gacgaagaaa gtcactcaca tcttctgaat caacagtaga
    74281 atcttctgat tgagaaattt cttcatccgg aagattttta ctgataaaca gttctaatcc
    74341 gtctcctttt ggcaaaactt ggaaagtgac agcttcgctt cctcggaact cctcttcgat
    74401 atcaacttct tccaaaatac tataaaagaa attttcgatt tctttgtgat tgccaagtaa
    74461 atccaaaaat gaaacgcccc gttcctctaa atcttcatga ccaattagta cacggatcgt
    74521 attttcatta atatgttcca tttccatttt gctacacctc actttgccac aatgtttaat
    74581 atagattcat tgtagcgaaa tcagcttaaa tgtaaagaaa aaaaatctcg ctgttaagcg
    74641 aatttaataa aaccagcgga tttttcaacc tttcaagcta tcttatttaa ctataacatt
    74701 tttggcagac gaatactata tagccgactt ttcagctaat tttccctctc tatttttcgt
    74761 gcaatcatca tcttctacta cctttttata catctaatca agaatacttt ttgtaaaaac
    74821 aaaaaaactt ggaaaaacta tctttgtaat agt
//
LOCUS       DBBGRF010000005        74586 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000005 DBBGRF010000000
VERSION     DBBGRF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 74586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.005"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            192..413
                     /gene="relB"
                     /locus_tag="ACIZD4_000361"
     CDS             192..413
                     /gene="relB"
                     /locus_tag="ACIZD4_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGC5989323.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            415..681
                     /locus_tag="ACIZD4_000362"
     CDS             415..681
                     /locus_tag="ACIZD4_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC5989324.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            848..1333
                     /locus_tag="ACIZD4_000363"
     CDS             848..1333
                     /locus_tag="ACIZD4_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989325.1"
                     /translation="MGWYGAYSSANEVIEEKKGYAKNGLEIVDTKVTKTYGIILFKDA
                     EGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFFVGDQEKMVKQQLDRIKEE
                     NNKPNLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQDGSLTRFTRLSAGDVKEV
                     A"
     gene            1827..2111
                     /locus_tag="ACIZD4_000364"
     CDS             1827..2111
                     /locus_tag="ACIZD4_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989326.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            2127..2264
                     /locus_tag="ACIZD4_000365"
     CDS             2127..2264
                     /locus_tag="ACIZD4_000365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989327.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     V"
     gene            2385..2639
                     /locus_tag="ACIZD4_000366"
     CDS             2385..2639
                     /locus_tag="ACIZD4_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989328.1"
                     /translation="MNYTDEEQITLEYVFTNEKGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            2721..2906
                     /locus_tag="ACIZD4_000367"
     CDS             2721..2906
                     /locus_tag="ACIZD4_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGC5989329.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            2973..3368
                     /locus_tag="ACIZD4_000368"
     CDS             2973..3368
                     /locus_tag="ACIZD4_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGC5989330.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEDLLEK"
     gene            3385..3735
                     /locus_tag="ACIZD4_000369"
     CDS             3385..3735
                     /locus_tag="ACIZD4_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989331.1"
                     /translation="MKSTHLNYFSRTLINNLLKDTTGISVSTKHFANDLIIFEDNNLR
                     IEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKKAKLLFEFQT
                     DYHNELLAQSEILD"
     gene            3757..4131
                     /locus_tag="ACIZD4_000370"
     CDS             3757..4131
                     /locus_tag="ACIZD4_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989332.1"
                     /translation="MKQTQTEPINDTLADQLAGYYKLFEMSKAQRLIHYLWKYKILFL
                     FWEATLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
     gene            complement(4437..4835)
                     /locus_tag="ACIZD4_000371"
     CDS             complement(4437..4835)
                     /locus_tag="ACIZD4_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGC5989333.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(5025..5792)
                     /locus_tag="ACIZD4_000372"
     CDS             complement(5025..5792)
                     /locus_tag="ACIZD4_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HGC5989334.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFKDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            complement(5827..6987)
                     /locus_tag="ACIZD4_000373"
     CDS             complement(5827..6987)
                     /locus_tag="ACIZD4_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HGC5989335.1"
                     /translation="MKITEKNVNPKFETTESNLKKFDLTVTLSNQLVDSIVEMDAMPQ
                     KIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSSSSKHSRLKQVIEKLHQQSVIK
                     IQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSSIMPLLTNLEDHFTQYTFDQVV
                     NLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDRLKNPVFSIADLRKKFSIEKKY
                     KAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTYTNIKFLLTRTMSVPVPYKQEQ
                     RDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFLISSADLCDLKLMSRLQNKVYP
                     LYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYLEKSITSYLPYVNLYD"
     gene            8031..8834
                     /locus_tag="ACIZD4_000374"
     CDS             8031..8834
                     /locus_tag="ACIZD4_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGC5989336.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            9419..9874
                     /locus_tag="ACIZD4_000375"
     CDS             9419..9874
                     /locus_tag="ACIZD4_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989337.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            9993..11051
                     /locus_tag="ACIZD4_000376"
     CDS             9993..11051
                     /locus_tag="ACIZD4_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HGC5989338.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            11093..13042
                     /locus_tag="ACIZD4_000377"
     CDS             11093..13042
                     /locus_tag="ACIZD4_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5989339.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            13045..16686
                     /locus_tag="ACIZD4_000378"
     CDS             13045..16686
                     /locus_tag="ACIZD4_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3659 domain-containing protein"
                     /protein_id="HGC5989340.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            17086..17424
                     /locus_tag="ACIZD4_000379"
     CDS             17086..17424
                     /locus_tag="ACIZD4_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989341.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            17534..17755
                     /locus_tag="ACIZD4_000380"
     CDS             17534..17755
                     /locus_tag="ACIZD4_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989342.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            17775..19931
                     /locus_tag="ACIZD4_000381"
     CDS             17775..19931
                     /locus_tag="ACIZD4_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989343.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            19943..20176
                     /locus_tag="ACIZD4_000382"
     CDS             19943..20176
                     /locus_tag="ACIZD4_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGC5989344.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            20166..21032
                     /locus_tag="ACIZD4_000383"
     CDS             20166..21032
                     /locus_tag="ACIZD4_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989345.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            21047..23017
                     /locus_tag="ACIZD4_000384"
     CDS             21047..23017
                     /locus_tag="ACIZD4_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989346.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            23184..23378
                     /locus_tag="ACIZD4_000385"
     CDS             23184..23378
                     /locus_tag="ACIZD4_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989347.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFKTIS"
     gene            23412..23747
                     /locus_tag="ACIZD4_000386"
     CDS             23412..23747
                     /locus_tag="ACIZD4_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989348.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(24004..25587)
                     /locus_tag="ACIZD4_000387"
     CDS             complement(24004..25587)
                     /locus_tag="ACIZD4_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989349.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            25709..26293
                     /locus_tag="ACIZD4_000388"
     CDS             25709..26293
                     /locus_tag="ACIZD4_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989350.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            26304..26549
                     /locus_tag="ACIZD4_000389"
     CDS             26304..26549
                     /locus_tag="ACIZD4_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989351.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            26555..27277
                     /locus_tag="ACIZD4_000390"
     CDS             26555..27277
                     /locus_tag="ACIZD4_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989352.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            27408..28151
                     /locus_tag="ACIZD4_000391"
     CDS             27408..28151
                     /locus_tag="ACIZD4_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989353.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            28157..28522
                     /locus_tag="ACIZD4_000392"
     CDS             28157..28522
                     /locus_tag="ACIZD4_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989354.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            28538..29068
                     /locus_tag="ACIZD4_000393"
     CDS             28538..29068
                     /locus_tag="ACIZD4_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989355.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            29230..29538
                     /locus_tag="ACIZD4_000394"
     CDS             29230..29538
                     /locus_tag="ACIZD4_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989356.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIERCH
                     YGQHFWTGEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     "
     gene            29669..29953
                     /locus_tag="ACIZD4_000395"
     CDS             29669..29953
                     /locus_tag="ACIZD4_000395"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989357.1"
                     /translation="MTFLNSVFIDYVITTKRIGSYSSTYASLVPMLNSMSRFLKEREK
                     KELQYIKEIMPDFEMHEWQIALSDWKLANKVRRITPFQAKRFLRAMKFVQ"
     gene            30090..30890
                     /locus_tag="ACIZD4_000396"
     CDS             30090..30890
                     /locus_tag="ACIZD4_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989358.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            30927..31109
                     /locus_tag="ACIZD4_000397"
     CDS             30927..31109
                     /locus_tag="ACIZD4_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989359.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            31220..31537
                     /locus_tag="ACIZD4_000398"
     CDS             31220..31537
                     /locus_tag="ACIZD4_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989360.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            31540..31683
                     /locus_tag="ACIZD4_000399"
     CDS             31540..31683
                     /locus_tag="ACIZD4_000399"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989361.1"
                     /translation="MLSDLFILLIYLGVSEIIAYFLFVIANYGISSAIVQMFRLPVSE
                     LKK"
     gene            complement(31887..32366)
                     /locus_tag="ACIZD4_000400"
     CDS             complement(31887..32366)
                     /locus_tag="ACIZD4_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989362.1"
                     /translation="MTDKTSDLPKLAPKTSRVKRKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            32451..33824
                     /locus_tag="ACIZD4_000401"
     CDS             32451..33824
                     /locus_tag="ACIZD4_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HGC5989363.1"
                     /translation="MKKSKRKIATLLMLMVQFTGIAMSVITINPQVIHADGIATYDAQ
                     FNCTTEGSGSGTDSDGNDTGSGAVSGDVAKNIDDIYKFMNGEYGLSGATIAGILGNWK
                     QESGNDPRTVEGYYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVNWAKKNFGGA
                     WWTTEAQLDFMFKGDGGFVAILKDYALNASDDVVANAVAFHKNWEISADSESAVVAVR
                     GGNAKEIWKYMKSKGMDGAKDVSKINKIAGGTSTGGGSNNSSSSASGTVEDACATTDD
                     ANSGSGSMGKEGKINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQ
                     GQCTELTWAYMSQLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWA
                     VGDAGHTGVVIAVFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGK
                     AKFEIEK"
     gene            33847..34374
                     /locus_tag="ACIZD4_000402"
     CDS             33847..34374
                     /locus_tag="ACIZD4_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989364.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            34361..34924
                     /locus_tag="ACIZD4_000403"
     CDS             34361..34924
                     /locus_tag="ACIZD4_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989365.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLENLDSYVRAE"
     gene            35347..36084
                     /locus_tag="ACIZD4_000404"
     CDS             35347..36084
                     /locus_tag="ACIZD4_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989366.1"
                     /translation="MADRKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANHQD
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            36201..37520
                     /locus_tag="ACIZD4_000405"
     CDS             36201..37520
                     /locus_tag="ACIZD4_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC5989367.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKHGRKIRLVVKREVNKFRYCGD
                     IRKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGVVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEDYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRKQYEEEKEKTFKAIRWDWGRQREIYMSKLW"
     gene            37976..38707
                     /locus_tag="ACIZD4_000406"
     CDS             37976..38707
                     /locus_tag="ACIZD4_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5989368.1"
                     /translation="MENSFKNKALYHQLVDLLKKRMESGMIPHDKLPSERELTAQYGV
                     SRTTVRLALQELENTGYIYRRHGKGTFVSDIKTAAADLAGAYSFTEQMKSLGRHPETR
                     ILSFEKMEADKFIAQRLNLPLGEAVFKLSRLRIADREPLMIEDSYLPVKFFLSLDDQL
                     LRSKPLYDLFSEDFKQTVRLADEELYASIASKDDAKQLMIPEGAPVLHLVRQTYNMKN
                     EIIEFTLSVARADQFHYQIRHIRNS"
     gene            38720..39892
                     /locus_tag="ACIZD4_000407"
     CDS             38720..39892
                     /locus_tag="ACIZD4_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC5989369.1"
                     /translation="MFTIEKEKLEQMGAEITTREIRQQPELWKETIDLYQSAQGELEN
                     FLTEVQKQAKGQRTRVIFTGAGTSQYVGDTLVPYLRKHGDRQAFSFESIGTTDIVAEP
                     EEYLIKEEPTLLVSFARSGNSPESLAAVEIANQVVDTIHHLSITCAKEGKLAQISQAD
                     SKSFLFLMPVRSNDDGFAMTGSFSCMTLGALLTFDQTALAEKQNYVETLNALGNEVIA
                     REHDIEEIVALDFERIVYVGSGSLAGLTREAQLKILELTAGKIATVFDSSMGFRHGPK
                     SFINEKTIMFGFVNNDPYTRDYDLDILEEVHEDEIASGVFAITQPGKRNFSGDTFEFA
                     TGTSLLPDAYLALGYVMVAQTVALLTSVKVANTPDTPSPTGTVNRVVKGVTIHDYK"
     gene            39915..40922
                     /gene="lacD"
                     /locus_tag="ACIZD4_000408"
     CDS             39915..40922
                     /gene="lacD"
                     /locus_tag="ACIZD4_000408"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGC5989370.1"
                     /translation="MLTLTTGKKAAMDRLSTKDGIISALAIDQRGALKKMIKALNVEP
                     TDKHIEHFKELVSSELTPYASSILLDPEYGLPAAKVRHADAGLLLAYEKTGYDATTPG
                     RLPDLLADWSVLRLKEQGADAIKFLLYYDVDEDPAINHQKHVFVERLGSECAEEDLPF
                     YLELVSYDAQISDAGSFDYAKVKPHKVNDMMKEFSKPQYKVDVLKVEVPVNMNFVEGF
                     GTGEIAYTKEEAANYFLEQSQATDLPFIFLSAGVSTELFQQTLVFAKEAGSTFNGVLC
                     GRATWKNGVKPFIESGEAAARDWLQSEGRENIESLNNMLKQTASSWHDKVQVAEEEAV
                     N"
     gene            40934..41896
                     /locus_tag="ACIZD4_000409"
     CDS             40934..41896
                     /locus_tag="ACIZD4_000409"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HGC5989371.1"
                     /translation="MIVTVTMNPSIDISYPLEKLKLDTVNRTDQVSKTAGGKGLNVTR
                     VIHDLKGDVLATGVLGGFHGAYISEELKKAGIKQAFTEIQEESRDSIAILHEGNQTEI
                     LEAGPTVSEAEQQAFLENFQELVKEAEIVTISGSLAKGLPLNFYQRLVQLAEEQVVKV
                     LVDTSGESLRQVLTGEHKPFLIKPNLEELEALLGQPFSIDDLEELQSALAQPLFTGVE
                     WIVVSLGKDGALAKYRDSFYRVTIPTIKTVNPVGSGDATIAGFAYGLSQKMSVTELLK
                     LCMAAGMANAQEVRTGHVNLANVDMHFEEINVRKASRTRSAFEQ"
     gene            complement(42127..42837)
                     /locus_tag="ACIZD4_000410"
     CDS             complement(42127..42837)
                     /locus_tag="ACIZD4_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5989372.1"
                     /translation="MVIPKYQIIKDELKQQIISGKFENGDKFYTEAELAEMFSVSSIT
                     VIRALNDLVKDGFIVRHQGRGSFVSRARKGKIVEFSDIELFPISNDQVQVLSITRGND
                     PVYLSKLELPDTAFYYCIKRLRKAEETPYIYQQTYLPEQYVNPNYQELSYYNSIYQRF
                     KLDYNIHMNEEDFTETNEIKFPTPSDAAKLLEISADEPTVLQVRVTKRRDTQQMLEYV
                     ESYKKWNFYKIELVSKNN"
     gene            43008..44786
                     /locus_tag="ACIZD4_000411"
     CDS             43008..44786
                     /locus_tag="ACIZD4_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase family protein"
                     /protein_id="HGC5989373.1"
                     /translation="MKTFEIKEDFLLNGEAFKIMSGAIHYFRIDPADWYHSLYNLKAL
                     GFNTVETYIPWNLHEPKKGEFHFEGILDLERFLSIAKELELYAIVRPSPYICAEWEFG
                     GFPAWLLNEDTRIRTNEIGYLKHVADYYDVLIKKLVPHQLSNGGNILMIQIENEYGSY
                     GEEKDYLRSVRDLMINRGITVPFFTSDGPWRATLRAGSMIEEDILVTGNFGSKAEENF
                     ASMQSFFDEHGKKWPLMCMEFWDGWFNRWKEPIVQRDAEELAEAVKEVLIRGSINLYM
                     FHGGTNFGFMNGCSARGVIDLPQITSYDYGAPLNEQGNPTEKYFAIQKMIHDTFPEIQ
                     QMEPLTKNTMEVKGIHLRNKVSLFSTLDTISQPVKTTYPETMEMLGQNTGYILYRTSI
                     KKDAEEERLRVIDGRDRSQLFLNQKLQATQYQTQIGEDIIVPMTEETNQLDILIENMG
                     RVNYGHKLFADTQNKGIRTGVMADLHFLTDWSQYCLPLDSCEAVDYSREWQPEQPSFY
                     RYEVVLDEVEDSFIDLSNFGKGVVFVNQVNIGRFWEVGPTLSLYIPKGLLKEGNNEIV
                     IFETEGTFQPEIQLVKKPLYKEMKEG"
     gene            44789..45268
                     /locus_tag="ACIZD4_000412"
     CDS             44789..45268
                     /locus_tag="ACIZD4_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HGC5989374.1"
                     /translation="MSIIGVRIDGRLIHGQVANLWTTKLNITRIMVVDDEVAQNDIEK
                     SGLKLATPAGVKLSVLPIEKAANNILAGKYDSQRLLIIARKPDRLLKLVELGVPIEEI
                     NVGNMSQTDETRSITKSINVVDQDVEVFNQLHAKGVRLIAQMVPSDKAEDFMNLLAK"
     gene            45281..46177
                     /locus_tag="ACIZD4_000413"
     CDS             45281..46177
                     /locus_tag="ACIZD4_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC5989375.1"
                     /translation="MDILWWQILLLTLYAGYQILDELQIYSSLSAPVFAGLFAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSVALGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDKLVEDMNYKGIERNFLMGAIPWSFSRMIPVFLAL
                     AFGGGLVEKVVAVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHFPYLILGFT
                     LTALLGTVFTNMQVLGTGVAGVVKNFEGIFNSLPMLAIALIGFALAAISYKNGQMIPS
                     SPAPKEVASNDSDEGEIEDDEI"
     gene            46164..46973
                     /locus_tag="ACIZD4_000414"
     CDS             46164..46973
                     /locus_tag="ACIZD4_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC5989376.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDDTPELKEIMKTHTQFFNTSNFFNTIVTGIDLAIEEKEGIGGKDTVSGMKA
                     GLMGPFAAIGDSIFAALIPTIFGALAANMAINGNPTGIFIWIIAQIAVMIFRWKQLEF
                     AYREGISLVTTMQHRLTALTDAATLLGVFMVGALVATMINVKFSWAPSIGDVTLNMQN
                     NLDMILPRLLPAGIVAAIYWMLGKKNMTSTKAIFIVLVVCVALSALGVISK"
     gene            47011..47415
                     /locus_tag="ACIZD4_000415"
     CDS             47011..47415
                     /locus_tag="ACIZD4_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC5989377.1"
                     /translation="MGKQLVLVSHGLFCEELKKSTEMIMGPQESIHTVSLLPAESAED
                     FRAKFEAVIADLDDFVVLADLMGGTPCNVVSRMILEGQAIELYAGMNMPMVIDFINSE
                     LIGTELALVESATSNICHVNERIIGDDDDEDE"
     gene            47559..48152
                     /locus_tag="ACIZD4_000416"
     CDS             47559..48152
                     /locus_tag="ACIZD4_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5989378.1"
                     /translation="MDFNEKLKQLRQNKQWTQEELAERLFISRTAVSKWESGRGFPSI
                     DSLKAISQVFDISIDELLSNSELLSIAENEQQQQRKNFQHLLLGISDCMVGLLIVLPI
                     FGQAQGNHIAFVSLWQLSQETIIFKLIIFSFVILTMLFGIFELAFSRREQRIIGSVSL
                     ILSLFGVLLFIMTRHPYPATYVLMLLAVKGISLLNSR"
     gene            48261..48920
                     /locus_tag="ACIZD4_000417"
     CDS             48261..48920
                     /locus_tag="ACIZD4_000417"
                     /inference="COORDINATES: protein motif:HMM:NF013718.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGC5989379.1"
                     /translation="MKIAKKQLETAIGLLIVFILYTISLSLFDVQKIGPQHSEVGFST
                     INQYVFQKIGTSEFWYQVTEILGIFPLIIVGYFALRGFFQLYTRKKLLLVDKEILALG
                     FLYAGVAACYVLFEKVIINYRPILVDGQLEASYPSSHTFLAITVLLSAFYVLRKETGT
                     GKAIIAYVSLVVMIALVIGRFLSGAHWGTDIFGGILLGLTLASCYLAGIESSSKQKKE
                     R"
     gene            complement(48941..49013)
                     /locus_tag="ACIZD4_000418"
     tRNA            complement(48941..49013)
                     /locus_tag="ACIZD4_000418"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48978..48980),aa:Thr,seq:ggt)
     gene            complement(49131..50279)
                     /locus_tag="ACIZD4_000419"
     CDS             complement(49131..50279)
                     /locus_tag="ACIZD4_000419"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC5989380.1"
                     /translation="MSKHKHQKRKKNKLTLVFPLFLILLAFSGMYAEHSYPEHHATKK
                     SSTPATKTTTDLTNQQPIEPKNATSAGIEQLLVEKNFSGTVLVFQHGQVILNKAYGWK
                     DQARRIHNTIHTQYCIGSVQKGQTAYLIMQAVKSGKISLEEKLSTFYPQISNSEKISI
                     KDMLNMSSGLRIDEKKIAALNTTDPQKILSETIRQTTVAANSSYSYQPVNYVLLAGIL
                     EQVYHTDYSTLFDKLLRKPMKLKETSFYSETNNQQALSYSESSSGPVYAPTTVSSYAD
                     ELGTGNVFMSGEDLYSYFQDLYQDKFLTTQERAALWQSYPGEKYASGIYNMTNNYHSR
                     GVKARFEALVDFSKDGQNGIILLSNVWTQPKGYNDIVSKLYKQVVAGS"
     gene            50410..50483
                     /locus_tag="ACIZD4_000420"
     tRNA            50410..50483
                     /locus_tag="ACIZD4_000420"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:50444..50446,aa:Asn,seq:gtt)
     gene            complement(50518..50934)
                     /locus_tag="ACIZD4_000421"
     CDS             complement(50518..50934)
                     /locus_tag="ACIZD4_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989381.1"
                     /translation="MNKKRKLSVLITLVSILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETVTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            51326..52573
                     /locus_tag="ACIZD4_000422"
     CDS             51326..52573
                     /locus_tag="ACIZD4_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HGC5989382.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETAKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTETDTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            52843..55233
                     /locus_tag="ACIZD4_000423"
     CDS             52843..55233
                     /locus_tag="ACIZD4_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC5989383.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     KFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGAFKQEGITVKDDGQTFEYTATNTLKKGVVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGISVK
                     DDGQTFEYTATNTLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDRNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            55282..57117
                     /locus_tag="ACIZD4_000424"
     CDS             55282..57117
                     /locus_tag="ACIZD4_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC5989384.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKSVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            57192..58049
                     /locus_tag="ACIZD4_000425"
     CDS             57192..58049
                     /locus_tag="ACIZD4_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC5989385.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            58039..59148
                     /locus_tag="ACIZD4_000426"
     CDS             58039..59148
                     /locus_tag="ACIZD4_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC5989386.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKTETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVIGALASLKVLILLIKEFRKA"
     gene            59487..60287
                     /locus_tag="ACIZD4_000427"
     CDS             59487..60287
                     /locus_tag="ACIZD4_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989387.1"
                     /translation="MVGVSKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            60393..61181
                     /locus_tag="ACIZD4_000428"
     CDS             60393..61181
                     /locus_tag="ACIZD4_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989388.1"
                     /translation="MSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWISAVGEEN
                     IEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVSWEMNNQ
                     YKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYAEYLKTE
                     RDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALSQYSSDE
                     EVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            complement(61198..62643)
                     /locus_tag="ACIZD4_000429"
     CDS             complement(61198..62643)
                     /locus_tag="ACIZD4_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HGC5989389.1"
                     /translation="MLGVILMMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFD
                     FIYPIVESTYSTYGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYS
                     FEDPIPHFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANA
                     NKHKFTKEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESG
                     YYVKGEREKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRV
                     VADAGYKTPKFVHFLSHLKLYPILPYTAPHGVKGMFRKKDFVYDAYFDCYLCPNNQPL
                     LFSTITRDGYRTYKSNPKFCVSCPLLENCTLSTKHQKIVTRHIWADLMDELEHQRHTA
                     LNREIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLW
                     KTKKPMAFYFKIMQRLTKRSGLITNSFLSTI"
     gene            62946..63815
                     /locus_tag="ACIZD4_000430"
     CDS             62946..63815
                     /locus_tag="ACIZD4_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HGC5989390.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            63835..64182
                     /locus_tag="ACIZD4_000431"
     CDS             63835..64182
                     /locus_tag="ACIZD4_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989391.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            64195..65457
                     /locus_tag="ACIZD4_000432"
     CDS             64195..65457
                     /locus_tag="ACIZD4_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989392.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            65537..66913
                     /locus_tag="ACIZD4_000433"
     CDS             65537..66913
                     /locus_tag="ACIZD4_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGC5989393.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGK
                     ADPEPQTSNNTNNKQPIASKTKPKANDPKGSENVVITTDKSEKKQINGSTSPIMQKML
                     KAKKQVHK"
     gene            66910..67539
                     /locus_tag="ACIZD4_000434"
     CDS             66910..67539
                     /locus_tag="ACIZD4_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989394.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            67558..68037
                     /locus_tag="ACIZD4_000435"
     CDS             67558..68037
                     /locus_tag="ACIZD4_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989395.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            68596..69195
                     /locus_tag="ACIZD4_000436"
     CDS             68596..69195
                     /locus_tag="ACIZD4_000436"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGC5989396.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIHFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            69211..69687
                     /locus_tag="ACIZD4_000437"
     CDS             69211..69687
                     /locus_tag="ACIZD4_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989397.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSEDSKSMRDLLITYLNEHEFEQTKVKKKNKK"
     gene            69704..70606
                     /locus_tag="ACIZD4_000438"
     CDS             69704..70606
                     /locus_tag="ACIZD4_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989398.1"
                     /translation="MLFTLLGYLCLVLAFFGAIAIFVGQFQANNPIMRNIGIGIVIIS
                     LIVFGATKIFGSNDQQFGISGVDNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNAVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGSDLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            70679..70873
                     /locus_tag="ACIZD4_000439"
     CDS             70679..70873
                     /locus_tag="ACIZD4_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989399.1"
                     /translation="MVVNKEKVRKYVTLKIASVEYLEKRAKEEEKTRGKKVTVSELLE
                     ELIESDQTIRRAFTNRSVKS"
     gene            70978..71406
                     /locus_tag="ACIZD4_000440"
     CDS             70978..71406
                     /locus_tag="ACIZD4_000440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989400.1"
                     /translation="MIIQKFDWKMKLGISLVILGFIIFLGIKAQKNQSTFETMSSQII
                     EECSKIYYCENKTEESNGFYYIDQPHDVVIKMESHEVNEWIQRSTNVSKKLERYSQTF
                     LSKVIFSNCKNKETSQRVASSLENLKFSVSKKEKFVDLRK"
     gene            71641..72228
                     /locus_tag="ACIZD4_000441"
     CDS             71641..72228
                     /locus_tag="ACIZD4_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989401.1"
                     /translation="MENNNDIRYFSIGERVTTVSELSKDYRDKEGTIISLKKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVFPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            72228..73127
                     /locus_tag="ACIZD4_000442"
     CDS             72228..73127
                     /locus_tag="ACIZD4_000442"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HGC5989402.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVADATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            73127..74041
                     /locus_tag="ACIZD4_000443"
     CDS             73127..74041
                     /locus_tag="ACIZD4_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989403.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPANSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            74093..74308
                     /locus_tag="ACIZD4_000444"
     CDS             74093..74308
                     /locus_tag="ACIZD4_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989404.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
BASE COUNT        26604 a        11084 c        14842 g        22056 t
ORIGIN      
        1 ttttcaacag gtaaccgata cattagtttc aatgtttact gagtaactaa ttattttgca
       61 ggaggacaat ttatttacac aaaattattg acgctcccat atgtttatgt ttatgtatat
      121 attcatatat ataactattg catttgtcat acaatcgtag tacaatgtaa ttgaaaagga
      181 gttgataaac tatgccagta ataagtattc gtgtatctaa agaagaaaaa gattttcttg
      241 aaaaagttgc tgaattcaac ggagataaca tttctgaatt tatgcgtagt aattccctgc
      301 aaacagcaga aacgttagta gactttgcca cctacaagga actaatgaaa gagcatgagg
      361 aaaacgatca aagtatttcc cacgaagata tgctaaaaga gttaggctta taagatgact
      421 taccaagtaa gatatgaacg tgaagctcaa aaagcgctaa aaaaaatgga taagtttcag
      481 gcaaaggtta tcctaaactg gatcgagaaa aatcttgtag gcactgatga tccaagaaaa
      541 catggtaaag gtctaacagc taataaatca ggctactggc gatatagggt aggtgcctac
      601 cgtataatag ctgatattag cgagcatgaa gtgacaattc ttatattgtc tattggtcac
      661 agaagtgaag tttataagta acagacaagc tgataaggct tgtctgtttt tttgttaacc
      721 caacaaaatc actgtttacg atcccacttt acctaaaaaa gaacaatacc ctcttgttat
      781 tatacacact ggtgtgtata atataagtgt aaacaagcta attaactttc aaaaggagcg
      841 attttttatg ggatggtatg gtgcttattc atcagcaaat gaagtgatcg aagaaaagaa
      901 agggtacgcc aaaaatggtt tggaaatcgt agataccaaa gtaacgaaga cctatggtat
      961 tatccttttc aaagatgcag aaggaaccta cgatattgac agcttcatct ttcgagatga
     1021 aatgtacaaa ccaatctact tcttaaatga cagtcctgct tactttaaga aaattccgaa
     1081 aaaatggttg aaattctttg tcggtgatca agaaaaaatg gttaagcaac aactagatag
     1141 aattaaagaa gaaaacaata aaccaaacct tgatgactta ttagttgcag gtaaaactta
     1201 ctcaatctgg gatggatcgt atgtcgctgt ttatcagtat aaactcaaac gtagctttat
     1261 ttttagacta caagatggat cactcactcg gttcactcga ctatcagcag gagatgttaa
     1321 ggaagtagcc taaaacttaa atacataaac ataaacgtgt atacgtttat gtttatgttt
     1381 atgtatatgt atatgaatat aaacgtatta ggtacgaacg tttttaaatg cttttctggg
     1441 ctttgatttt agggtagggc taaaacatcc attgatccaa aacagctcag aaacgcattt
     1501 aaacgtatct gataccaata ttacagaagg agtgtatcgt atgattaacc tatttctttt
     1561 agtgacagct agtacattat tctttactgg aatatcactg ataatttcct atttgatcta
     1621 taagaaagcc gaaacttaca caagcaaagc aaccggacta gccgtttcct cctttttaac
     1681 tttgctgact ttttttgtta ctctatcgtt ttcttttgtt tagcacagct gatccatcag
     1741 caaaaaacct ctctttacat tatacacact agtgtgtata atgtaattgt aaacaagcta
     1801 attaactttt aggaaggagt gacaatatgc taacagctac attacagcaa cctactcacg
     1861 ttgctattgc agaaagctat acaattaatg caggggtcgt taaacagctg atcaaggatc
     1921 gagaattcaa aaagtttaac agtcgtcaag cgtataacag acagttaaag aaagctattc
     1981 taaagcacaa aaattccttc atagggaaat tggaaagtgt ggatgttaaa actgtttcaa
     2041 cggcattttc agttgttgaa gtgactattg acggtcgctt gatttctcta tttgcttttg
     2101 gaattaattg atagggagtg tggactttgg aaggtaagac ttttgcagaa atttggactg
     2161 aatttattga ggtaccaact cgcattgatc cgataacttc tgaaaaggta ttggatgcag
     2221 acttctacaa tctcaaagca ggtactagcc ttgaatgcgt ttagatgtat ttagaagagc
     2281 atttcaaagg cgtaacgctc ggtcacgtct tataccacaa tggtgccgag tgggatgcaa
     2341 ttggaaatat ccatttttct taatacaaga aaggagaaca caatatgaat tataccgatg
     2401 aagaacaaat cactttggaa tacgttttca caaatgaaaa aggggaggaa attgaaaaag
     2461 tcttgatcat ttcatcaaaa gacttggaga acgctttgac ttatgaacca tacgaatcaa
     2521 ccgtaactgt caatgaattc ttagatacct atacttctaa tgatacttgg gaaattatga
     2581 atatttgcaa cgctaataac attcaatttg ctgaaaaaac caataaatca ttttattagt
     2641 tttgcaataa aacatcctct ttttctattg attccataca caacaatgtg tataatagat
     2701 tttgtaaagg gagggtagct atgcctaaga cagcaagaga aattgtaaaa attctcaaat
     2761 ctaacggctt caaaaagact ggacaaactg gcagtcatgc aaaattttat aattccaaga
     2821 ctaaaagaac ggtcgttgtt ccgatccaca atggtgatgt accactagga acagaagcta
     2881 atatctggaa gcaagcaggg ctttaacagc cttgccttcc tatttggtat taggcatact
     2941 atcctctctt acactagaaa aggagcgagg aaatgaagac aaaaaatatt ttttatccgg
     3001 caatcttcga gaaagaagga gaagcttata acatcgtttt ccctgactta ccggaaatat
     3061 ctacctttgg aaatagtctt gaagaagcat atttaaacgc taaggatgct ttaggattag
     3121 cgctatatag tgtaccagat gcagaatttc ctaaaccatc agcagtggaa gaattaactt
     3181 tgaaagccaa tcaagtagta gtaatcatcc aactaaacat taaacttttc cgaagaagct
     3241 taaatacaaa aacaattaga aaaaatgtta gtgttccgga atggttagtt cttttaggga
     3301 aggagaaaaa cataaacttc tctcaattac ttcaaaaagc actagaagaa gacttgcttg
     3361 aaaagtaaaa aggagaccga acctatgaaa tctacacact taaactattt ctctcgaacg
     3421 ttaatcaata atctattaaa agatacaact ggcattagcg ttagtaccaa acactttgcc
     3481 aatgatctaa ttatttttga ggataataac ttgcgaattg agatgtttat tgaacaggca
     3541 actcctaact caatacctga attctgctat acgcacactg aaaaaatgaa acatgcaaaa
     3601 tcagttaaag atgttgaagc attaagtgaa tcactaacga acgctttaaa cctcgttaag
     3661 aaggctaaat tgttatttga atttcaaacc gactaccaca atgagttgct tgctcaatct
     3721 gaaattttag attaattgaa acaggagaag agaaagatga aacaaacaca aacagaaccc
     3781 attaacgata cgcttgctga tcaattagca ggttattata aattatttga gatgagtaaa
     3841 gcacagcgct tgatccacta tctttggaaa tacaaaattt tgtttctttt ttgggaagca
     3901 acactaacat tctcagttct tttttataag tcagattttt ataatcaaca cttagtttta
     3961 gggagttttt tgcttatcta caccattttg atgcttaatt tatataccta catcacactt
     4021 gaagaacact tagtaattag cgatgcaggg atcgagagaa acatcaaaag ggtatctttc
     4081 aagatcacgt taaacaagcc taccgataaa aagctctcag aagcgttctg agagcttttg
     4141 acattttctt gtataattta tcctaacaca ttacaaagca cctaattcga gcttatatca
     4201 agcaaatttg ctatttattc ctcaatacat atctaaaaat tacttgatgg aaaactagat
     4261 acatggtaag catgaaaaga aaatcaattt gagcagatgc agtataatac atagcaattt
     4321 aaaagctctc agaacgcttc tgagagcttt taatatattc tttgataatt tgtctttctt
     4381 aaatccatac gtcctaaaac aagctgtttt tgcttaatat gatcatctga gagacatcaa
     4441 atcaactttt ctctcaacaa atcattcaaa gctttcgaca gattaatatt ctcttcagcc
     4501 gctaaaacat ttaaatagtg ttccacagtc actgattttc gatcataatt ttgcttgttt
     4561 cgagctttag caactttcgt attagctttt acgacaaata aattaacatt ctcagatcgc
     4621 ttgattcttg catttaactc ttgaacaggc gtaggcgatg gaatttcttt ttcttgcaac
     4681 tctaaaagca ccaagtatcc ttccaatact tcttgcgcca tctcaaaagc atcttctaaa
     4741 gtttcaccat gcgtatataa gtctggaaaa tctgggaatt taactgcata ttcatttcct
     4801 ttccattcga atactgcaca aaaaaagtat ttcatcgcat tgcacctctc taattaaaaa
     4861 ataatttttg ctttttggtt tcaaaaaaag aatcgcctac caaaaaattg ataggcgatc
     4921 acaagctaat taacctctaa aggagattaa taccttgctc ccaaggcact acatatctta
     4981 acatacgtct gaagcatctt caaacgagta agatatattt tgcattaacc taattttttt
     5041 tctctataag gtttttcatc aaactcacta gaaatattaa actggacagc aaaattgtaa
     5101 tttctgcctt ttctaacttt agcaaaatca atcttcagca ttgatttttc attaatttct
     5161 tcaactgatt cccttaaaac acgtctatca aaattcgata ttgttttata ctcattttct
     5221 gttttcgtaa tctcacgaat tttaactatt tcaatcaggg gattcttata tatttcagct
     5281 ttctcaaaat ctcctttatt tttggcgata agatattttt tataatacat cgccaaatat
     5341 ttgtataaca cgatgctata ttttttttga aaagatgcta agtctttaaa aacaaagaac
     5401 ggatacttct ttttgattga gacaattaag ggaattacat cttctgaaaa actgaaagat
     5461 acactatgct cttctaaatc ccaatgaatc cgatcaatag cagatacagt agtatacgtc
     5521 ttatatttct tgtctagatt cgatatttca taaactgctt gtctttgcaa agtgttaact
     5581 atggttttta gttccgtttc aagattttga tcaacatcca tgtaattaat aatcgcttta
     5641 acaggtaaat ctactacgcc tgttttcttt agctttgtgg gtgagatata actgaacagc
     5701 aattgataaa gttcatacga ctttaaatcc attttcatat caattgttgc taagaactcc
     5761 tcattgtact ttgtcagttc atcttttttc aaaagttttt ccttccttca cgcatttttt
     5821 cagttgttaa tcataaaggt tcacataagg caaataactc gtaattgatt tttcgagata
     5881 tttaacagta ttttttattg tgtaatcctc cttatgagta gcaacgtaag ataggtgatt
     5941 gacaactgat tcaaatcctc tatctttgga taaacgatca taaagcggat aaactttatt
     6001 ctgaagtcgg ctcataagtt taagatcgca taagtcggca gaactgatca aaaagttttt
     6061 gattagtaat ttagtgtatt tgctattcat agctttcaag tacgattgat tcattttctc
     6121 tgttttatct tctgcgcctt ttaaataagc agggtctctt tgttcttgct tataaggtac
     6181 cggaactgac atggtacgtg taagcaagaa ctttatgttt gtataagtat gacccttctt
     6241 gataagctca tagtcaattt taaaatcagt gtatttattc agttgggcaa tcggttcttt
     6301 aattacacgt ctttcaaagt ctcgaaaagc tttatatttt ttctcaatac taaatttctt
     6361 tcgtaaatct gcaatggaga aaacaggatt ttttaatcta tcaagtgatt ttgtactcca
     6421 tgttaagtta tctctatttg cttcatacag attaaaatct ttagtgaata attgaaaaaa
     6481 actgatcgca tacttgcttg tcaagttaac tacttgatca aatgtatatt gcgtaaaatg
     6541 atcttctaag ttcgttaata aaggcataat tgaactacta aatttaatag atactgcatc
     6601 agaaaaatca ttgaattcag taatttctag cggtgagatg actttgtatt cagtcttacc
     6661 gttaggttta gttctttgaa ttttaatgac agattgctga tgcaattttt caataacttg
     6721 ttttaatctt gaatgttttg aagaagatga actagaagac atcaacgcaa ataaagcctt
     6781 tttagatact ttgacggtat tattaaaagg cggattttta gggtcaagat gtcctatagc
     6841 gtaaagataa attttttgtg gcatagcatc catttcaaca atgctatcta caagttgatt
     6901 cgataaagta acagttaaat caaacttttt tagattgctt tcggtagttt caaatttcgg
     6961 gtttacattc ttttctgtta ttttcatacg attgcctctt ctttctaagc ttggtacgag
     7021 cttaaaaact tggaactggt acgattccat tgaataagta tagacctgtt ttcgatacgt
     7081 tacaataaga aatgtatcgt aaatttataa cataactcaa tgtcagtaaa acacatttta
     7141 ttttttccaa tcaaatttca ttgaaaatac agcagaaatc gctattttag aacattttca
     7201 aaataaaaat ccttttcaat aaaatacgaa attataaaaa ttaccaaaat taaaaaacaa
     7261 atatttttct agtttttaga aataaattca catacttttt ctttttttgg atatattcgg
     7321 aataccacat cgctttttgt ccacgtttgc atcgcttttt gtccacattc acatcgcttt
     7381 ttgtccatgt tcgcatcgct ttatgtccac cctaaaatct atttaagatt gatataaagc
     7441 ctttttggag gttgctaaag ttttaaagat taaaatatat attataaata taaataaaag
     7501 gggaagctga agcttcctcc ttttcctttt tttcaattat tcaaagttac acaagcaaaa
     7561 taaactccta gatagtgtta gtttttttta agatttttta tttttaagat tttgaaataa
     7621 gagaggagta atcctccttt attaaatatc tgttaatata tctgttaaat atctgttaat
     7681 atatctgtta ggggaggctt aatctcttgg gagagtaagt attaaagggg tataaaggta
     7741 acacttttgg acagtaaagg taacaaaagt ggacagtaag ggtaacagtt ttggacagca
     7801 aaggtaacaa aagtggacat ttgaggtatc acactaggat aagacgttac cttcggtttt
     7861 cttgatttgg aaggcgaaaa aatagaaaat tagattagta acaaatcttt gttgactgtt
     7921 acctttagtt gtgatttaat ttaggtaaca agcagaaaaa attgtttcct ttaattagta
     7981 ccagattaac atgattaaag gagcgcaaaa agaagattgg agagtaatca atgtctcaag
     8041 aagttaccga aaagattatt gatagtgatg tagatttagt atcagaacaa acaaatgcaa
     8101 ttgtgcgtta taacaatggt ctgaatacaa cagctttgcg aggatttaag cctgttgaaa
     8161 tggatgtgtt ttgggctatt ttatcaaaaa tgaaacgtca aggaacagca gaagtaactt
     8221 ttgatttcaa cctctttcgt tatttggtca aatacgacag aagagaaaag gacagttttt
     8281 attctgtgtt aaaagatttg agtgacaaac taggtaattt aacctaccgt tttgaagatt
     8341 cagacgtcta tgaacagctg tggctttttc aaaaattccg gatagataaa cagaaggaaa
     8401 cagttacaat taaggcaaat gaggaatttg aatttatctt aaactcaatt ggcaaaaact
     8461 ttactcgttt tgaacttgat aattttacaa aactaagaag tagctacaca aaagaattgt
     8521 atcgtcatct catgcaatac agaaataaag agtggcgaaa tggttattgg gtagtcaaag
     8581 ttgaagattt tagaagagca ttaagtatac cttcaagtta tagaatgaca aatattgata
     8641 aaagaatact agagcaggcg aaagaagaat ttttagctcc tgatgaaaac ggaatacagg
     8701 tatttgaaac ttttgattat gaaaaaatct atgcaaagaa aggaagaaga gttgatcggc
     8761 tcagattcac ttttagtgag ccagaatcaa acttgccaac catttcaatg cataattggt
     8821 tagaagaaga ttgagaagaa gcaggttgta attttaatac aacctgcttc tttaaaaaag
     8881 tatgggtaac acttttggac aataaatgca agaagttttt ttgtaagcaa gtttcagtct
     8941 aaataatatt tgaaagaatg gctaatctat acaaatttta acaactatgg gtaacacttt
     9001 tggacaagtc aagaaaaaaa acaatttttc ttaatttgtt gatcgactaa aggtaacact
     9061 tttggacaac acagaataaa aagtccggtg atatcagttt tggtaggaaa catcttaata
     9121 tctttgtgag attgaaggta acatttttgg acaagtcaac tatttgttaa aagttaatat
     9181 agagtaatta gataagtttt ttcttttcgt ctgataaatg gataatatta gttattttat
     9241 tgctaattag tctttcatga tgactgaaat agctaaaata aatatctcgt tggataattg
     9301 ctgatacttt aagggatatc taaatttgct gattgattta tttatgttat tatgatatta
     9361 taataacata aatgtgttac gcccgaacct cattttaaaa aaatgaaggg gtgagacaat
     9421 gaatgctatt aattggcatg aatttgttaa ctatatggag agcttactag atgatctaaa
     9481 aagttttagt attgctgatg cagtaaagca tgggttacca gttagtacaa cgatgaaatt
     9541 acgaggattg aaaattccag atgaaattat taagctgaga actaaaacaa ttattgaaac
     9601 cgcaaaagtc gttgacaata tgaaccatga actaaaaggc aagaaaacaa cttacgagaa
     9661 agattttgaa cgttttttaa aatctgttat tggaaaatat ctaggtaaaa aatctttcag
     9721 tgaattgaga gatgaagaga ttgtacctac tccaatggtt agcaaaatcc gaaaaaacaa
     9781 agccgagggg aattactatc ttggtacaat agcaaaaatc attgattatt tggaaaataa
     9841 agagcaaaag aaaggaacga agaaaggaag ataatttttg tgttaaatat taatggggaa
     9901 gaatataccg aaatgattca aaatcccgaa cctagaatta ccgaaaaaac gtctgattgt
     9961 ttgctctttt atgaaagggg gcagacaaac taatggaaaa aaacgtcaat tcaacatcta
    10021 ccaaagatca atacagtatt attggagggt tgcttggtga taaggataag agaacacgtc
    10081 acggattacg cattatgctt gcaacttttc taggagtgct ttttttatta acaggcttgg
    10141 gtagctacat ttatcaatta ggaaactata attattatct cgtgaacaat acaacaccta
    10201 taggctcttc attggagttt gctcgatcag gagcagagat cactatttca gatgtgtgga
    10261 cagatcaaaa cagagatgta acagtagtaa aactcggtta ctcgcaaaac gctagaaagt
    10321 tgttatctac gcaaggaaaa aactacaact tatatatggc aacgaaagaa aaagatcgtc
    10381 ctaaaaagct tgaaatgagc tatgggatgt taagtactga tggggatgct ttcttattcc
    10441 taaaaggtaa attagatgaa agagcttatc aagtttttat tgcaaaccaa gtatcactaa
    10501 tttctggtga tgatacagct gacgatgata ccaaagtcaa tgtgaatgaa gcagattcag
    10561 ttacaaaagc actttctcaa tattctatga atgatgttaa taatgaagga gtaatttctt
    10621 ttgggaaaaa agcaaaacct gttaatactc ctgataatat caatttcaga ataaatccat
    10681 attcagattc aactaatgtc tatcaaggaa gctttcttac caaagatggc gatattgatt
    10741 attcaaaagt tgtagcagtt acaagtaaga ataatgttgt aagtaagtta gaagatcagt
    10801 taaatgcttc aaatactaac atcaagaaaa ttgaagctac aaaagctgag tatctggaac
    10861 gtttacaaca aaatcctgac gataaagatt cgcaagaaag tattcgtcaa ctagacagtc
    10921 gaatggagac cgaaattaaa gcaatcaatg atacacaaaa attgattgat caatacaaaa
    10981 atgctgactt taacaaagat tcttttggag acatgaagac gacatttaag tacctaactc
    11041 tgactgacta gaagtaaatt attcttattt tagaggaagt gaacacaaac agatggaaaa
    11101 tagtaccgag ttttttaaga atattcaaac tgaatttaat catgctctca caccaatgaa
    11161 accaccgaaa cataagttag tgggacgtga tgacgaactc catgagttgt cactgatctt
    11221 gaatagaccg gaaacaccgc aagctatctt gttaggtgaa gccggaacag gtaaaacagc
    11281 acttgcaagt gaatgggctg aaagacagcg acaagatgga aagaaagtac aagtatacaa
    11341 attatcaatc ggacaattgc gtgttggggg agatgatgtc ctccaaacac gtttagaaac
    11401 attaattcca agattgaaag aatatgagcg aattttaaaa tctgaggaca aagaaaatga
    11461 atttgtcctc ttcattgacg agtttcataa agttgttagc tcttttggta gtggcaataa
    11521 aattgggggt gattcgctaa aagaaccgtt agcaaatgaa tcacttcaat tgattaccgc
    11581 tactacaaga aaagaatatg aaaactatat caaaagagat gatgccttag ggagacggtt
    11641 acaaccgtta gaattgaatg aactaaaaag cgatgttgtc gtcgatattt tgagacaatg
    11701 gctaaataca tcctctgtta aagatgatcc tcaggcttct tttaaattat cgcaaaggat
    11761 tcctgatgaa ttacttcaag aaatcgtaca agcaaacaag ctttatcgtg aggatttgtc
    11821 cgaaccggct aaatcaattg ccgtaatgga ggatttgatt gcaaaagatc gagtagacgg
    11881 aaatgcttat aatcgagaaa gtctattgca aatatttggt aagtataata ttcagctaga
    11941 ttctgatttt gatatggaaa aacttcaaga ggaattaaag tccataaaag ggcaaccgtt
    12001 agcagtttat actataacaa tgttgtttaa acgtatgaag cttggatttg atcgttttaa
    12061 aggtcgaaag caaccaaaag caactgctct gtttacagga tcaacagggg tcggtaaaac
    12121 tgcaatggct aaagccgtgg caagaggact ttatggcgat gaaaataaag ttctcttagt
    12181 taatatgccg gactacaaaa caaaagatga tgcaatgcgt tttagacgac tcataggtac
    12241 tcatgtaagg catgatcctt ctgcgattat tgtgtgtgat gaatatgaga aagctggtgt
    12301 agaaacactc gatgcctttt tatcaatttt agatgaaggt aggataagtt ttactgaaag
    12361 aggatgggat gatcgagaag ttcacgacac tgtttcattg tcaaatacaa ttttatttgc
    12421 gacaacaaat gcaggtgcgg agatgttcga ttcgttaaac agatatagct cactatctcg
    12481 tgttacaaac aaggaaaatt ctaatgaata tagcactgaa ctaaaaagag aataccgaaa
    12541 agtcgcatca gggatcaaac aagccttgat tggtgaaggt ctaaagcctg aagttattaa
    12601 ccgatttgga cgaatagttc cattttgggc tttatccgaa caaactcttc tggaaattgc
    12661 ttataatgaa atgttgaaga gtgctgaatt agtacgaaaa catttaaata tagatttacg
    12721 tcttccacct aggaaagaaa gagtatatgg tcaaaatttt tatgcagacg atctctccat
    12781 gcacttagtt tttgacatgg cttcacaaga ggattctaaa tcagggggtg caaggaatat
    12841 cttgcattta gttgaatctg agtttgaaga agcgattact gaagcaataa ttacttatcc
    12901 aaacgcaaaa atattcgatg ttaagttgag tgaagccgga gcgtttgaag gaaaaggtga
    12961 ttctaatgct gaaattattg caaagccttc cgttgctgaa agtaaagaaa acaagattgt
    13021 attttcgatt ggaggggcgt agctatgaaa ttcaagaaat atttactaca aaaccttaga
    13081 ataaaacgat gggtcgtaag aggtctagtt attggaggag tattagcagt tactttaggc
    13141 gctccttttg gaatgaatga tccaactcct gacaatcaag atagcaaaca agaaacagtt
    13201 ataaataaga acgttgcata tgcggaaagt aaaccggcag aacaaggaat gtggacacta
    13261 tatgctcgta tcctaatggg agataaagaa gttaatgata gtgccgctaa aactggacaa
    13321 atgaatttgt taggacaagg tggtatcagt gccgatttcc cttattctga catttctaaa
    13381 caaggtaatt cgattgcagg gggtaatgca ggtactcaac tagcatctac tttagcaact
    13441 tatagttact acggatatat tgaaacagtc tcaggaaatg ctattgccag tcaagcatca
    13501 tccattctag gaagtattgg taggacgatt ggtagtttta tcggatcaat tagtttaatc
    13561 ctttctaata ttgctgaatc cataaatgaa ctccttggaa aatttttcat gagtatgaat
    13621 atattttctc ttatggggtg gggagaaggt ggatcggatg tatctaatcc ggtatctaaa
    13681 gcattaacta gcttgcttaa caatttggga ttaaataatg aattatttaa agcgatagca
    13741 agcttatcta tgctcttttt cacagcaata ctaggttatc aaggaatgaa attattgtcg
    13801 aaagatggtg ttaactcgaa gggattatca ccagtacttg aaaaatggat tgttcgtatt
    13861 tttgtattgt ttatattctt accagtggca ggatcgctat tgggagttta tatcaacggc
    13921 atccagtcag caaaaaaaga tggagatata ccaacaaatg ttgtttctga ctacatcatt
    13981 aacacaagac tttgggcttc tactcaaaat cttgctccat catctgatac tggtggtgat
    14041 gtacctgacg gaaagcctac atccgaaatc aagttcgttg atacagatta tgaaccatct
    14101 aaaaaatctg caatgataag agcgatcaat actagcagtt atgccagaca aaataatgat
    14161 ctagattcta attcagtcgg tatggctcta ttaaaagaat ggtcatcgaa tgatactttc
    14221 aatattaata cttatgccgg tgatgttaat gtcgccgaaa atgatgctta tatgggaaga
    14281 gcgcctgctg tttggacagg ctataattta ggggatggaa aagaaggaag tgcaattaag
    14341 aaaccaacca atttaaatgg atatatttgg tcagcaaatc aaaatgtgac agacgacaat
    14401 cgcaagcctg atggaaaagg aacagcgcat aactttgatg ctactcaacc ttggggcgtt
    14461 gctaacaatg caacttttag cacacagtcg gtagctttat tgctccaatc ggcacttgat
    14521 acatcgggag ctaagtttta tgcgtataat atcgctcctt caggaattca aggcagtgct
    14581 aagaatatgt caacagtaaa aacagaatgg cgtacagcat ccttagttgg tcatggagct
    14641 atgggtaagt ttggctcgtg gctagcgatg aacgctgaat caatcgtttt agcagttctt
    14701 tacttagcat gtgcttgggc gatgttcaat gtgaatatcg tgaaagcatt taaacgtgaa
    14761 tttattcgga tttgggaagt agttctaaca ggatcacttg catcaggagc aggtgtgatg
    14821 gcaatttcat taggtgttgt tacaacatct ctgatcggac tacaattacc tatctttctg
    14881 attactttta ttcgtgcatt tggtgatact gctgtgggat tcattcctaa tacattagtt
    14941 ggcgatggcg tagcaaatat tgttcgatct gctatgattt taggtgtagg atatctttta
    15001 gtctttaaaa aaggcgaaaa agtaaataat ttgattaata tgcttattgg cttaccactt
    15061 gaagtagcgt ttgggtttga tgaacgtgct aagttattat ttggtaatag aaatgatgct
    15121 gtgcgagttg tggacggcgt ttctaaagca atcaagaaaa gccaaggagc taaaaatccc
    15181 tattatgatg gtggcaacag ctcagtaaaa gatatggttg caggaggtct tggagcagtt
    15241 ggagcgcaaa aaatggctga acgtttgaac aatatgggag atagcaatgc tgatgctaag
    15301 tccattgctg ataaagtaat tcctgaaaca ccagaaggaa tgtcattcaa cggtggcgga
    15361 gttggttcca caatcaataa tacctctttc aaagatttag ttcgtcaaga tcaactacgt
    15421 aataactccc aacaatatat tgatcattta ggacgtatgg ttgatgaaaa cggaaacttt
    15481 gtcgatgaaa atggtgaaat attaaaagat agtaaatacg gtaaagatgc taaaggcaac
    15541 tttattgacg aaaaagggcg tttggtcgat gaagatggaa accttataga tactaatggt
    15601 aaaccattgg aagatagtga agatggtaat attggtatgg atagcgaagg acgtttaatt
    15661 gatgaaaaag gtcgcttagt cgatgaagat ggaaatcttg ttgacgaaaa tggacgcagg
    15721 ttgctaaatg gtgattttgg tcatgatagt aacggacgtt tagttgacga aaaaggtcgt
    15781 ttagttgatg aagatggaaa tcttgttgat gagtttggta ataaacttgg taaacacagc
    15841 gatggatata atgtgaatgg agatttagtc gatgaggatg ggaatatcat tgagacgaga
    15901 gatgcgcttg tggcagatcg aaatagagaa ctcgaacaac aacggcatac gccaattgct
    15961 gttgcaattc ctgagaatga agaagacgag attactttag atcaaactca tcaagaactg
    16021 aggaatgaaa tgagtggtga ggacgtgtca gacagagtgc atcgagaatt aggagatgga
    16081 gcatctggtg aaagtcagtc aagagagctt aacagcaact ttgataatag tgctattcgg
    16141 aatgacacag tacttaaaga cagagaatcg ctaacaaaag aaacggataa agaacaatca
    16201 gatgtgaaga aaaagttcat tcctactcct aatgttaatc aaacagataa atatgaaaca
    16261 aatattggat caggaatgtc gaaagacaat caatcaatta gagaacctga actgacaaat
    16321 aaaaataata gaacaaataa ttctaaatct acttcagata attcagggaa atctaatcaa
    16381 tcaaccaaga aaacatcaac agctaaatca gccgttgaat atctatcaaa aactggtaaa
    16441 aatgtttaca cctcagcaga taaagcttta gcaaaagctc caaaaggtag tctagcaggg
    16501 ataacctatg aagctaaaaa cgaagctatt aaaataggta aaggaacggc taaggttgcc
    16561 aaggctactg ctacaggagc atccaaaact ggtaaagtag tgaagaaatc taccatgtca
    16621 gtcaaggact atattgtaaa atacggtaat caaaaatcaa ctgaaaataa gtctgaagac
    16681 gagtaaaaag aaggagcatt gatttgctcc ttctttttac tttgatttct aactgaagat
    16741 gtcaaggaaa atttctattt atgcaaaaaa attattttaa attgtctata aatgaattaa
    16801 atatttactg ttcaaagttg tataattaaa aagggcttat gctggtaaag aacagaatta
    16861 ttatctaaac aaaaacttga taaaccagca tttttagcca ataaaaaaag tgaaataatt
    16921 taatggaaaa tctcttttaa tcatcgaaaa tttatgttat tatgataaca taaagatgta
    16981 aatatcgaga cgtctttttc ttagttagat cattgacaag tgaacaaata agatttgtcg
    17041 atgatataat taacttatta aaaatattaa aaaggaggtt tttatatgtt cgattctatt
    17101 aaaaatttgg ttagcggaat gacgcctgat atgaaaactt tagtacaagt tgttttgtat
    17161 ttcttggcat tcgttttttc gttgaaacca ggattcactg caatgaaatt ttttggtgat
    17221 gcaaaatggg gagatggatt aaaatatgtt ggggcgatta ttgcaatctt tattattcct
    17281 gtaattacaa ccgttatgct ttacacaatg ggtactaaaa caggtaatga tttgaaccaa
    17341 aaagctaata tcatatcagc acttattcca gttgttggta tctatctagt ttcaaaattt
    17401 ccaaaaaatg aactgttagg ttaaaagtga attgaacaaa tttggataat atgccgattt
    17461 gttcaattta ctttttacca aaaaactacg ctccaagcgt agtttagaag tgagggaaga
    17521 aagtaaatgt aagatggttt ttgatagaga aaaaatgtta gctcacgcca acgaagtatt
    17581 aatgagcagt ctgaaaggta ccgaactggc aaagataatg aatatgaatg ttaaccagtt
    17641 ctatgattat cgaaatggga gtaaaaagat tgaaaaagcc agacttgaaa cgcttattaa
    17701 attcgaaaaa gcatatgtat atatgctaga taaacagaaa agaactattg actgaaaaaa
    17761 ggagttttac aataatggca aaattcaaag atattaccga atctattaat tatgtggcag
    17821 aaacagttcc tgtagttgca ctctctttga agccacaatt actcgaagtg tacaaaaaag
    17881 aagaaaaaga agcgaaggca aaaaaagcta aagcaaaggt atggaaagaa ttcgatgcgt
    17941 tgctgaccaa agatttacca aagaaaaatt atatggtaat tgaagatgta caaaagctca
    18001 acagtgaggg agttatagat gaggatgatg ctattctcga ttctgagaag tatgtcgttc
    18061 tattgaagtc aagtttgaat tatgtagctg atctaccaga aaaatttaaa gagaagctat
    18121 tagcaggtgt ccgttttatg gatagtagtg gtcaattatt agttattccg gatgatccta
    18181 atgtgtttga atcagaagtt gaagaagcta cagacttcta tagcgcagta gagcaattag
    18241 aagtagctac taatggatta gaacgaattg ctgagacctt caactcttct gaagaagttg
    18301 aatttgaagc cgtagcagaa aatgtaccag atgaaaaaga agctcttttt gtggatgata
    18361 acaaaccaac cgaagcagaa aaccaagaag taagcataga agaaacacaa atacaaacag
    18421 aaacctacca acaaccaaaa attgatgaaa aacccgaatc ccaaagtgac aaagaaaatt
    18481 atgtttatga agctgaaaaa atcacatctg aaagtgatgt accgaaaaac ttagatgctg
    18541 attttttaga aaaaaatttt gaacagatca ttgctgacaa atttcaacct gtagttttag
    18601 atgagattaa tgaccctgtc gatttaaacg aggagatgct atccatacct gagttgaaac
    18661 cattgctgtt tttagctaaa gagagtatga acgctcgcat ctctattgct aataataaaa
    18721 tcaacagtga attaaataag acgaaggagc aattgatcct caaaggaaag caaatgttag
    18781 ctgatgagct tttgcggata gaggaagcaa cctcattaaa tggtcaaaat cagtttacaa
    18841 atacactatc ggttgctaaa gagagctacg aagcagaagc atctaaaatt gatgatttag
    18901 tgatggaaaa atccaatatc attcgtaaag attatgatat ggcgaaacag gcttatttgg
    18961 atgctgaact aaagaaacta gagcaacggt atgatgctga gcatttacca gaagttaaac
    19021 aacaagaaga tgaatataga aaagcaactg aagaaagtct tgatcaacag taccaagaag
    19081 caattgaatc tattaaaaac gatgcattga aacaaagcca agaagcaaaa gaagttgtgg
    19141 tggaacgaat tatcaattca ttgaaaccag aaattgaaaa atcattaaca gacgtgcaag
    19201 aaaaaacttt agagattgtc gaaaaaacaa agtcagaaaa tgaagctgag ttccatgata
    19261 caaaagagaa aacaacagat gtggttgtca aatattttgc gaacaaagaa gaagttgaaa
    19321 agcaggtagc taacaacacg aaagaattag aaacaaaact tgtagagcaa caaaaaacta
    19381 tcgaagaata taaagatcga atgaaagagg tcaaagattt agcagagggt tataaattaa
    19441 atagcgaaaa gttggcagaa caaagtgaag ctttaagaga agacttatct cgttcccgaa
    19501 gtgatctagc tcaaatggca gaaaaaacga aatcattagc agttgctaca gaaaatcaat
    19561 caagttcaaa acgtgatttt acaagtaaaa agatggctac tatcatttct gtcgctgcaa
    19621 tggcttgcgg aacgatcttg ggatcgtcct actttattag tcataataat caacaagcac
    19681 aggctcaaac tcaaacatct atttcgagag tggaaaattc gattgggaca aatacgaact
    19741 ctgcttcaac aaatagtagc tatgaagcaa caccaactac agagttcaaa gttgggaaag
    19801 atgttgtcat cagtattgat gggaaaacaa ctaaggctga agtgatttct attgatggag
    19861 aaaaagcagt tgtgaaaact ccagacggaa atcagtacaa aattcaagct cacttatctg
    19921 ataataacta aggagggcta ttatgcgaga agaaaaaata gtttatccag taattcaaaa
    19981 caatcaagaa aacatgacct cttctcagca cttacaggaa gcacagctcg tgtatcaggt
    20041 aaatgaacta ccacaaacga acgagacaat gagcaagtca atatctttaa ttggcttgct
    20101 tattgttgca atagtgataa ctgtaggtgt ttaccgtaag ttgaacgtga aaggaagtat
    20161 ttctgatggc agataactca aactatggat ttaaacataa cttacatcaa aaaccttctg
    20221 aaacaattgt cagagttgaa tggcttgaaa agcatgtcaa tagcacctat tctgttacag
    20281 caaaaagatt aattgtatca gctatagttg ttgcagtcgt tgttcttgga tcaattgttt
    20341 acttagtttc tgatacgatt aaactgaaat ttatttttgt tccaacgtta ttaatgataa
    20401 ttggatttct tattctaatt agccagtata tgtttattga tccatctagt ggttcattga
    20461 tttctggttc tattagactg ttcaaatcag tagttaattc agcaagagta tctatgggga
    20521 aaaagaaacc atttcgaggc acagagattt taaaagtgaa acaagatgga acaatcgtat
    20581 atcgagatgg gagtgtagca ttaatgttca atctagatgg ggctacatca ctaaccgctt
    20641 ttccagaaga agttatggct caggaatcga aatcaataca atatcaaaat accagagatc
    20701 gttccttagc tgaaatcaaa atcacttcat ctcaacctca gaatacggaa agacaaactc
    20761 gaaatatgaa aatacaaaaa cgaaatgcaa ggagtaacaa agcagtcttt gacataatag
    20821 atcagcaaga acgatttgta tcagaatata ttgatggtgt gaaaacaaca gtaatccaat
    20881 atcttatctt gaaatctcaa tctaagatgg tattggatga aggtgtggaa cgtttagaaa
    20941 actatacgag tagaggactt tattatagtg tcactcagtt gtcagctaaa caaacaaaag
    21001 aaatattatc tgatatttat gcactgaaat agaggtgaga gattaaatgg aaattatggg
    21061 tagatcacaa ctattaaatt tcaaaaaaaa gagaaaaact aaaaaagaac aaaaaactag
    21121 aaattcaaag gtagtgaata atacctttgt tagtgattta acatctttag ttggttatca
    21181 atttacacca tcttacatta ggacaggtaa gcggtgggga acaattgtga aattagtgaa
    21241 tacttatgga atgaatagaa attatggatt tggttggatg gttaaagcta ttcctgaagt
    21301 gagagtagaa ggggtaaaag cctatctaat tgaagcagat aagccagtgt cacaaaaaga
    21361 tcaacaagaa ataatgcacg agaatgttgg gggatcaacg aatagttatg aaaataattt
    21421 agaaggaaaa aattcagatg ctgaaattag caaaactgtt atgcggatta tggatttgaa
    21481 tacagcatct ttactagaca gcatggcaaa taaaattatt gattggaagc tagaaatcct
    21541 attagtatcc gattctccta ataaaatcag cgaacagcta attaaactcc aacggttgta
    21601 tgatgaaaaa atgtatggat taaagcttat gtcatatgga ggagatcaac gtgatctgtt
    21661 tgatagactt ttaagtgaac caatcgggaa tgtctatgag tatacgtcta tgagttcgga
    21721 ttttgcagga aatgatcatg caattcgcaa aggtttagat gatgcgaatg gatgggctat
    21781 cggcactatg tctactagct acgcaagtgg tgtagctttt atggcactgg atgattcttt
    21841 tacaagtaaa gttttagtgg catcacacaa aaacgctaca attaaaggct atgatgaaaa
    21901 aatctcagca tcatcacttt gggggcaatt gattgctaat aatgcaatgg caaatcataa
    21961 acgaactttt catattgtct taaataaatt tgattacttt ggtgatccaa ctggtagaac
    22021 atttgttgcc aaaccttcgt taaacagtgt aatagaaaag gttaatttgg ctgaagaagg
    22081 tcttaactct ttggagcttt ttggtaatca aaaggacatt ggtgatttat atagacggaa
    22141 tctcgataaa ctaactcaga ttttttattt gttagcaggc agaacattag attctgcaac
    22201 tagagtttta ttgaaaaaag aattaggtaa cttttatata agtcagaaac tttgggatat
    22261 taattatgaa gaacgttcaa aacttttggt gaacagtagt gatacaatgc cagttcttgg
    22321 ggattttatt agctatttga ctaatgctga aacaaaagcc aaaaaatctg gtactgaaaa
    22381 agaagtcgat cgtattattg tattaaaaga cacattgaga acagcattag acagcttctc
    22441 taggatgttt aatcaaagaa cgacactgaa agaaatcggt aaaagtgaca aattacagtt
    22501 ttactataac ttaggtgatc taagagcaga aaccaatgtt atggaagctc aatttttaaa
    22561 tacctttgat ttcatcacat cacaagcaaa aaaagatgat attgttatga ttcacggctt
    22621 cgataagtta tctattgaaa ccgttgggct aattaaaaaa agattaacaa tgcttgaaga
    22681 agatggaatt cgtcttgcct ttctatttga tacaatcggt tcaggagaag acaatgaata
    22741 caaagaagat attgaaacag ctgatatatt caatacagat ggaaaaattt accaaagttt
    22801 tgaaagtgat tttaattaca ctatcattgg aaagatgacc agtggagagt taatgaagta
    22861 tgaaaaaaaa gttgctcctg ctagaaaagg agaagatgat caaaaacttt ctgttgattt
    22921 gagacagtat ttgacaacag gaagaagtaa taaatttcag atcaggagac cagtggatct
    22981 gactaataat tttgttattg gagagtttat tctttaagtt ttatctttga ttttgagtgt
    23041 ataaggaaag gataagaaaa aacatgtata tttgagacta aaaacagtct tagagaacat
    23101 ggtacgtttt gtgaaaagag aactatagaa atttcataaa gtgaaacctt actgagtgaa
    23161 ataattatag tggaggttaa ataatgaaac caaacataaa aattttagat cgaatatttc
    23221 taggtagaga cacagaagta atcctaattc aacatgaaga aggatttgaa gttagtatag
    23281 gtattcagaa acttcaaaaa cctcattatt gtaatcagtt gtataaaaac tttactgatg
    23341 aagaaaaagc gagagttttt tttaaaacaa tttcctagga aaaatagtta acataaaagg
    23401 aatgaattgt tatgaaacaa tatttaaatg aatggaaagc gatagagggg tcattagtaa
    23461 cgcaaagaat aaaggaatta cctgattgct tagagaagga tcatttgttt caaatacgag
    23521 aaatgttgaa aaaagaacag tttgatccag accaattttt agtagtcgag tatccaacta
    23581 ttggagtgta ctgttgtaac catatcaatg atggaaaata ttttattatt caggagtatg
    23641 gaggacagtt aactcctttc tatactacat gggaaatgag tgaagaagga atcaataatt
    23701 ttccatgtga aagcatcgaa gattcaattt cacacaccga atgttaattg attataacta
    23761 taaaaaagga ttgaacatta tgttcaatcc ttttttcaat gaaatgtttt ccgccatttc
    23821 attgtttggt gcgatttcta ttttattata tcaaaataaa gagagattct aaagaaagaa
    23881 gagggaaata tataaatcaa gcgacagtat atttattatt aaatgctatt gtgagaatat
    23941 aactaattag tttaatttga aagtaaatat acgctataaa agtgcatctt gtgttataaa
    24001 aaattatttt attttgtgaa cataatttaa caattctttc tcggaattga tttcttttct
    24061 taaatagtct tcagacttat taataatatt atctattatg tctagataca tatcactttt
    24121 cgattcagct aattcataca gtttttttaa ttctttatcc tttaattgaa aaccctgatc
    24181 catagtcact gcatttggat atagaagccc actataatgt ttacgtaaat tcacttggaa
    24241 tttctgatta taaaagtcta acagattaga aataaaaggc ggaaaattac tgtttttgta
    24301 aaattgatta tttccattta ggttgtatag taatttgtta aattgctcct gatttaattt
    24361 attgtaaatc catggtaata cttccatatc cttatctgct aacctgaatg aactagcatc
    24421 ggtaagatgt tcgatcataa aatctatgaa catctctttt tcaccaaaat ataaatattg
    24481 attatatatt gtttctaatg ttgaagatgg tagcgaagaa actctcattt tttgctggag
    24541 tataggatca actagactat ttaagtgatt ttgtaattct tcattgttgt ttcctagaac
    24601 tgcaagggaa cgtaaacggt agtaatattc tatttctgtt agtacttgtt gtttcggttt
    24661 aaaatcattt attgatattt gtaaattttg aattgtctcg tctgaaaaat catgttgtaa
    24721 ttctggatgg gtagctataa aagtaagtaa aaagaaccct tttgtatacg tgatctgttg
    24781 attttcacca agtgatttat taatttcctc tcttgattca gctgtgaacc tatactttgc
    24841 aatttctttt tttagaatat ttaaatagaa ttctttatta tcaaaaatta gggcattaag
    24901 tagtctgaaa gtactttccc tatctctatc tgcttcctca tttccataag ataattgaaa
    24961 aacaaactta aaggctgtct tacataggtt ttctttggct ttttcgctta gtttatttag
    25021 atagctattt tttagtgcag agtgaaattc ttcaggtgta acagacatag catgtatgcg
    25081 acttgcatat tgtataattt cgatcgttac tttttttcct aatattggat tttttaggaa
    25141 tataatttca taggacttcc gtataacatc ctgacaagtt tcttttgtta tatctcttaa
    25201 ttcccaagta ttaccgttgt aagtgactac aggatgagct gaataatttc tttgatcctt
    25261 aatatatttt aaatcctcat attcatagct atcaattagc tcagttgaac tataagcttt
    25321 ttctagtagt tccatttccc attttggaga gtttggatca ctttttctta gtctagctat
    25381 atcttctaaa attttcttag aagtattatc ctcgtaaata tttgctaaat cagataattt
    25441 atcaattaaa tctaaaataa gcgcactgta attgacagct attgcagaac gataatttcc
    25501 ctgataaaaa ctacttctaa cttcttctaa taatggaata attctaggat ttttaacttt
    25561 ttttatttca tcatctaata taaacatata aatctccttt ttttatttgt atgacaagtt
    25621 taccataaaa aaaaattaaa aagcgagaca tatttatgtt gttgtgttat cataataaca
    25681 taaatatgta gagtgagatg atgaaaaaat ggatttgaaa caatcgtttt acatctggtt
    25741 atatcctgat aatcctatgt caataatggc tgatattttt gtagttagca tcttattgta
    25801 tttattttat ctaattttct ttcacaattt aatcgggtac atgattcttg attggaaagg
    25861 aatgttcgat atagaaagaa aaccatttgc taacaatcaa acctataccg tcttcgaaag
    25921 tggagattgg gaagaaaatg aagttgatgt gatccatgaa attggattag ctttatcagg
    25981 aatacaagat gctgatgttt tggtatcaat gacaacggat actggataca acgcttatga
    26041 ggtattttat cttatgtatt ttatatggcg tgatggtcaa gaaattatca atggtcgtgc
    26101 tgaaaaaaca atcaattcta atactgaaat ttctttttgt atgggtgaag gggaaatgat
    26161 tgtatataaa gatgggtcag caaacattaa aacagccttt ggtgatattg aaacaagtat
    26221 taaggaactt agggaatatg tgcagaaccc atataatttt caatatttag caggaagaat
    26281 aaatttagtt taggagtaaa aatatgaaaa aaattataaa tcaaccaaca aatcacttga
    26341 taattgaagg tgttattttc gtaacaatgt attttactgt aggaaatggc atctcaaata
    26401 caatcattca aaaaaatcca caatacctat tatttagtct ttatgcttgg attgtacaaa
    26461 tggtttgggt ttccatattg atgctgttgt tttattggat agtacgggtt attcttttat
    26521 tgttaaacaa aagaaaaaag gataggtgaa taaaatgaaa tcaactaaat tgaaggttgt
    26581 attgttatcg acagcagcat taataaccct tacagcatgt ggtacaacta atagtgctaa
    26641 taataacaaa gacacaaagt ctagtagtac gatggttact aaaaacagca ctacatcggc
    26701 atcaacaaca atgtcttcaa tgactgaaaa taatgctgaa aagtatcaaa aatacgaaga
    26761 cattaataaa ggtcaaaagc cggatgaagt ttataacaac tttattaata cagtaaaaaa
    26821 tgatgaaaat tatgggaatg atccattgca aaataaaaat ctgactatcg ttctttacaa
    26881 acctgattgt ccagattgtc aaaaagcaga atcaaaaatc atgcaagaaa taaaagaagg
    26941 atttagttat gctccaacat taatgcatga tattaccata aataaaccag cttacgagta
    27001 ttacgcagtt gctgtagata ttactgatgg tgtacctgag tgggtacaaa acattcctgg
    27061 tctggctgat gagaacaatc aatatcatac gccaacagtt gcagtagtaa caccaaagaa
    27121 agttaacggc acactatact gggatgtaat gggaatgaca acaaatacaa ctgatgaaat
    27181 gattgaaagt acaactaaat attatatgga tttgggagca tataaattat atcaacaatc
    27241 agagcctgtt atggacgatc aatccaaagt taaatagatc tttagggcgt aagccctatt
    27301 tttttaaaat taagtgataa caaataaatg atttctgaaa caaacgttct tactcaacta
    27361 ctcgaaacac acaagctaat taactagatt ataaaggaga atgcgtaatg aaagaaatca
    27421 gtgcaaatga agctcatatt ccgcaaaaga atcaggttgg tatatataag gtgcttcatg
    27481 gtgaaggaat ttataaaata cagttactta ccggttacaa taatggtgca aatgggaagt
    27541 ggttaaaggc aacaagtatt cgtgaactta gaagtgaagt agaaaaaatt aggcttggtc
    27601 tcacaagtga agaaatagct aaactgaagg gaaataattc ttttgtaatt gaaaaagaaa
    27661 aggaaaaaca tctactttat cgtgagctga aaattgaaga atactatgaa attgatttac
    27721 ctgaaaaatt aagaattatt gatcaacgtt cagaagaaaa atggaaaact gaaatatatc
    27781 caagcttaaa tgactacaag acatcaggaa agcccatgta taactacaca ggctttttaa
    27841 cctacacaca atacaaatat gcctttcgca aattaaaagg cattaaacaa gctgaaattg
    27901 ccctgtatga gatgaaaaaa gtggatagat tgaaattgat tcaagattta gtgcaaaata
    27961 catggaatca agcgattgtc gagctagaaa aagaaaatgg gaaaatttta actaataaat
    28021 atctgatcgt aaatgaaatt gaagaattaa ttggtttatt ttcatgtgaa aaaggtgaag
    28081 tcttcttgaa gtcatcacca acctattcaa ttttggacag tccgtatcag tttatacagg
    28141 caaggagatg agttagatgt ctagcttgaa agatgactat atccaagcaa aacaagagta
    28201 tgaaaaaata cagatgttga aatctgagaa agtcgaatta tttttaacac aaaaattagc
    28261 agaggatcat attgctaact tagatgctaa aactttagag gaatatgatc ggcagtttaa
    28321 tcagatacat cacaatatca ttttgcttgt tgagcaggca aagcgaaggt ttgaaaaagc
    28381 ggaatatgat ctattagatc aaggaattgt atgcttggat aagggattgc gaagatatta
    28441 tggtgcagag ttaaaaaagc aaaatgtaga tagaaatgca ctaaaacatg aaatcttaga
    28501 attgataatg caacgaattt gaagggatag aaagcaaatg tcacaaaaca ttagtgctgt
    28561 aaaacaatta atagaagaag atttagagac cacagttcag agattagcgg aacgaatcca
    28621 ttttgcaaat tatcaaacca tctctaactg gtcaagcagg aacagaaatc cggaagaaat
    28681 tccaatgaaa tttttttatc gaatcggaaa agaatatggt gttgatccga taaaaatttt
    28741 cgagaagacc atgatttatt actatcatgg aacacctaac gaagtgttag aacatctttt
    28801 ggaagaggca aaagaaaaat catcaatatt agagctatcg caaaatgaca aagttattca
    28861 agtgaaatgc gttgatccaa caggaaagat tattgtcggt tttgatattg aaagaaaatc
    28921 caaaatagat tttattacac aattaaaaaa gataaataat ttagatattc taacgcttag
    28981 accagatcat gaacagttgt ttatgagttt taaaaaacaa ttgaaagaaa tacaaaaaag
    29041 atataacaag gtgtttccta atgcgtgaaa agctcaaaga aatcagagtt ttttggataa
    29101 ttaacaaaga atgtatcatc ttatatactc ttggatttct tagcatgatc ttgttttggt
    29161 ggttatattt aaaacagtaa ttggagaggg tcaagaggat ttttatcaag ataaggatgt
    29221 ggaaactgca tgtggaataa tagattaaaa acaggattgt tattaatagt tatttcctgc
    29281 gctatgatga ttggtatgag gatacaaagg gaacaatcct attttgaagt ttctgctaac
    29341 aatgtaatag aaagatgcca ttatggtcaa catttttgga ctggggaagt cagagaaaat
    29401 atagatcgtg aatatgttca aagaattgtt tgggatgcat attctatcaa agattatcct
    29461 aaaagtttaa cgagtagatt attttacagt gaaaaagata atcaaaaact ctcagatttg
    29521 atgatgaaaa aagtatgact attattacga aagagaaaca gagtgctata ttcgagggga
    29581 aaaagcctac aacaaaagtg actattgggg tgacaaggcg aagcgattaa ctgcaaattt
    29641 tagagtgtat gaatcagagt ttataaactt gacctttctt aatagtgttt ttattgatta
    29701 tgtaattact acgaaacgca ttggaagtta ttcaagtacc tacgcatcct tagttccaat
    29761 gttaaactcg atgagccgtt tcttaaaaga aagagaaaag aaagagctac agtatatcaa
    29821 agaaatcatg ccggattttg aaatgcacga atggcaaatt gctttatcag attggaaatt
    29881 ggcgaataag gttcgtagaa taacaccttt tcaagccaag cgctttttga gagctatgaa
    29941 atttgtgcaa taaaaaaagc caccagacaa gttgatggag actaacacaa ttaccaacag
    30001 ttgtaattgt gttagcttac aaattaatta tggtgtttag tcaatcccaa attgtgaaat
    30061 ggcaccaata attggaaagg aaaaatgaaa tgtctgaaga tttacgagag ctgaagttac
    30121 gaaagaagca gtatgatcag tatttttccg gtttgttgaa taaacatatt gaagaaggac
    30181 ttgatcatga ttttggaaaa gatgaatatt gtttatattg cgaacgttac aatgaaaaaa
    30241 tgtctgaata tctacagctg aaaaaagaga tacagaaatt agagaaaaaa gtacatgctt
    30301 ggaagtataa agattccatg tctggttatg ttgaatctca aaataagcca agaaaaaaga
    30361 agcaagcgta tgttctaaag atggtaaatg gggaagagtt aattgtatta gcgtacagtg
    30421 aagaagaggt tcgagaactc gttgaaacac ctgtcaggaa aaaggttgaa acaataaatg
    30481 agatagacga cagccaatac aatagcatct atattgaaac aagtcatggt ggatataaga
    30541 aattagcaac tttccttaga agttctaaag ttgggataat ttctaaaaaa gacataagtg
    30601 ctgttaccga tagtttttgt actttatctg ttcctaaagc ttatttccaa tacgatagta
    30661 aaagatttga acgcttagag aaattctgta gaccgtatac tgtattgaaa actaaaaaat
    30721 ttaataaaac taaaagagtt tctatacagt taccgactgg tcaaatctca ttaggtgaaa
    30781 aagactatct gataaaagta ggaaaagagt taattataaa agtaccggaa cacttattta
    30841 aagaaaattt tgagatacgt gaaaccttgg tatggaaaga agaaaaatag tttggaagac
    30901 atagaatggt ataaggggaa attgaaatgg cagtaaataa aatattgcag gtactaatca
    30961 tagacgaatt tggcggagga gaatggtttg atgtgcagtc catagacttt gaagaagaag
    31021 tcgtagttat agaaaatatt tacggcgaag tatattcata ttcgcttgaa ggtgagaata
    31081 ttgaggattt acggttgatt ggtgagtaga aaaaaacaga aatatcaaaa tggagataaa
    31141 aattaatagc atgtaaagat agtcatgctt gggttaaaaa tgttaaaatt caaaaaaatg
    31201 agtcagaagg gataaaagta tgaaaagaga ggaatacaaa caaagattaa acgaactgct
    31261 tgaagaggac gaaacattaa ctcatggttc gcctgatgaa attctataca tgattgataa
    31321 tatggtgatc tttggtggat atgaacttgg taataggtca gttgatcata atattttaga
    31381 atttgatgat gtatcatggg aagaaattct tgattgggga attttggcgg tacctgaaac
    31441 taaaacctat attagtgaca ctatggttcc tttttttgag gaattggatt ataaaagact
    31501 tcccaaaaat gaaaatcata tactgggagg aaactaacaa tgttaagtga cttatttatt
    31561 ttactgatct atctaggtgt aagtgaaatt attgcgtatt ttttgtttgt cattgctaat
    31621 tatggtattt ccagtgcaat cgttcaaatg tttagattac cagtaagtga actaaaaaaa
    31681 tgatgagatt atcagcatat cttttaatgt ttttgaatgt ggtcacgtta atctttgtag
    31741 taatcggtgt gactttcgat ttaatggaat agtgggaaat ctataatgga aaaaagagac
    31801 acgaatgaac atattttttg aatcaatatt gttgatggtt tttgcgatca gcgcttacca
    31861 gaaatctaaa aaagagtaat gattgtttaa tcatcactct ttttttgtag ggaaattgaa
    31921 atatgtggag cttgtattgg tttagttagg attgcttggc tataaggagc tagttcttta
    31981 tcaaaaccat caaagtaggt tttcagtagc gatttaactg atcgctcatc ttgtttgatt
    32041 tggataattt cagcatccaa atcggttgtg agatcaggag cttttgatgc gattacctga
    32101 ttttttttat cttccaactc tcttaggctg tttaacaagt tgtaaaaaga atcattttga
    32161 ttgttcattc caacgtgagt tgcaatttta acagaagttt cgtccgtatt gtcatcaaaa
    32221 gaactcattg gaatatcaag tagtaacgag gatgtttctt ttactgactt tttctttaca
    32281 gcattttttg tttttccatc tttttttctc tttactcgag atgtttttgg agctagttta
    32341 ggtaaatcac ttgttttatc agtcatttat tagcttttcc tttctattaa tttatgttat
    32401 tatattatca taataacata aaaaaagtac actttttggg ggcgtagtta ttgaaaaaat
    32461 ctaagagaaa gattgccacg ttgcttatgt taatggtgca atttacaggg attgcaatga
    32521 gtgtaatcac aataaatccg caagtgatac atgctgatgg gatagctact tatgatgcac
    32581 aatttaactg tactactgaa ggtagtgggt caggaacaga tagcgatgga aacgatactg
    32641 gaagtggcgc tgtatcaggt gatgtagcaa aaaatattga tgatatttac aaatttatga
    32701 atggggaata tgggctatca ggtgctacta tcgcaggtat tctaggtaac tggaaacaag
    32761 aatcaggtaa tgatcctcga acggtagaag gttattacgg tgatggacag agagaagttg
    32821 acttcatcaa acaattcact gatggtctga tgggtattgg ctatggtcaa tggacagcag
    32881 gtcgccatac tgcattagta aactgggcga agaaaaactt tggtggcgct tggtggacga
    32941 cagaagcgca attggatttt atgttcaaag gtgatggtgg atttgttgct atattaaaag
    33001 attatgcttt aaacgcttct gatgatgttg tggcaaatgc cgtagcgttt cataagaatt
    33061 gggaaatttc agcagattcc gaatcagctg tagtggctgt acgtggtgga aatgcaaaag
    33121 aaatctggaa gtacatgaaa agcaaaggca tggacggagc taaagatgta agcaaaatca
    33181 ataaaattgc cggaggaaca agtaccggtg gtggatcaaa taattcatca agctcagcat
    33241 caggaacagt agaagatgcc tgtgcaacta cagatgatgc taattctggt tctggatcaa
    33301 tgggtaaaga aggaaaaatt aacggtaaaa aaggtcaagt aatagcgaat atgacttatg
    33361 aagaagcttt gaaaaaatat gggaaagcga tcacgctacc aaaattcaaa gaaccagatt
    33421 ggtcaacttc accttttaac ggaatatatc aaggtcagtg tacagagttg acgtgggctt
    33481 atatgagcca attatacgat gggaatcaac cgactactgg aaatggtggc tacgtatggg
    33541 aaagctacaa atcggcagga gcgaaaataa cgaacaaacc aatcgtaggt tatgggttta
    33601 gtgcttcaga tggatggtta tgggctgttg gcgatgcagg gcatactggt gtagttatag
    33661 cggtgtttga agatgggtca tttctatgtg ctaactttaa tgttccacca acccaagctc
    33721 caacaagggg agtttcggta actttgattg atggagtgga cggatcagat aatgtgcatt
    33781 tctttagcgg tgtaggaaaa gctaaatttg aaatcgaaaa ataaattgga atgaaggacg
    33841 atatagatga atagtaaagt gaaagataca attatcattt ctttgctttc tggtatgtta
    33901 ttagcactgc ttgttggaat cctattcttc aataagcaga atcaggacat agaagctgaa
    33961 aaacacagtg tgcatattga agataagctg acattcttta aagaggttaa accaaatgag
    34021 gtggatggat tacggaaaga tttagaaaat gatattcaag aaatgttgaa tggatcagtt
    34081 caaaataagt ttgcagatca atcaggtgaa gaatttttga gaaaactatt tattgtcaca
    34141 ggtaaaccac caattactga taagagtagt gagaaagaaa aaatcgagta ctataagcct
    34201 tttactttta agctaacaaa ctttggaatt aagacatcta gtagtgggtt gtatgaagca
    34261 ttgaccgatt ttgaagttca atacaatgga aaaaaagtgt atgataccac attaaccatc
    34321 acactaaata atgataagaa agtgactggg ggtgcttttt atgcaaaatc atgaaatcac
    34381 tactgctaaa aaggcgattg gaatactttc cataattgtg atcctttgtt gtgtggtact
    34441 atttcaaaag aaaaatgctt atgataataa tgtcaaagaa ttggaagacc ttaaaagtaa
    34501 acaaatcgaa gtagtcaaga ataaccagaa agtgaaagct atgcaggaag cccaatacaa
    34561 agaattgggg aatgctgaaa tcaaggaaca aagtaggaaa ttctttaatt tattttacaa
    34621 ctggaattca tgggaaaaat atacgaagaa tatgaaggaa atacaaaaag aatttcctca
    34681 gatagtaaag tctagtcctg ttgatatttc tggcacgatg gtaggcactg gtaatagtcc
    34741 aatatctagc tatactgctg attactatac aacaaatcaa aaaggtaaaa tggttgaatt
    34801 gattacacag acaagaaata ctccaacaac agcaacaaca acaatttggc gtggagtaac
    34861 aagcatagga gaaaatcaat tgttttactt ggagaattta gatagctatg taagagcgga
    34921 gtaaaataaa aaaagagcta acggtaccaa cgttagctct ttgtgctgac gatgataaca
    34981 aaacctaccg aaaaaggatt gtttcatcac aaacacaaac agaaaagaat tgataaaaaa
    35041 cccgaacctc agaattttta ttaatcaatt catttagatt ataataaatt gagctgaaca
    35101 ttacaatacg tatatgttgt aaaacgtaaa aaaagtcaaa agtaaatact ttcttaaaaa
    35161 gtcaaataaa actattaaag acaatatata tggtttattt gacataagaa aatggtctag
    35221 atgataattg taatatagaa ttgtaggctt aaataaagca taaaatacct tttatgataa
    35281 ggtatagctc ttaattttaa gcagttttta gatataagag tgaaagtaaa gtgggggaga
    35341 ataataatgg cagatcgtaa attagaaaag ttattagaag aaacgtggaa tccaaaagaa
    35401 tttagtgaat tttttatgga gaattttgaa actgacttag cagtgattgt taaagatgct
    35461 cttagagagc aagggtatcc tgaaactgca aactatataa acattaattt tactttgtat
    35521 actgaaaata aaggaacttg ggatttttgg gctactttag caaataagga gttaagtgat
    35581 aaatcagaca caggaattcg taactttttt gaatcaaaca gagatgatta tatgtatgct
    35641 aaccatcaag ataaattgaa ctttagagta gagtttgatg aaacacctga agaatttata
    35701 gaaagacaac cgcctaaaga aaatgtagca aaggtattgg aagatcgttg gaattcagat
    35761 gaaatagttt caacaattag cgaactaggc ggacaatatg aaccgctagt agaagcggtt
    35821 agagaagagc taagactgaa taagtttcct gatgttcaaa atattgatgt ttctcaaatt
    35881 gaaataaacg tcaagatcac gaataaactt gattatggta gttgggcaga tatagcatta
    35941 gaaaaataca tctactcaac gttaaaagag tttatcgaaa atagaatgga tatcatgtat
    36001 ctacagcatc cacagtattt aaactttggt gttgaaatag ctacacctct tgaagaatgg
    36061 aaaatggagc aagggcttga ctagcctttg ctccattttt ttaacagtaa agaaagtata
    36121 aaaagttaag gactaaaaag gctgcactac cagtcttttt agcccttttc attttgtttt
    36181 tgaacaagta aaatattact atgaaagcga atattctcga agcaatcttt tttgacgaac
    36241 accataattg ggataatttt gttgagaaac acgggcgaaa gattcggcta gtcgtcaaac
    36301 gggaagtaaa caagtttaga tattgtggag atattcgaaa aggataccga ctgtttgtct
    36361 gcgaaggatg tcatcaaaca aagtttgttc ccttgaaatg tcgtggaaaa ttctgtccaa
    36421 catgtgcaac aggtgaaagc caaaggtggt cagcggttgt ggcgaatgat atgtttaaag
    36481 tgacacatcg gcacgtaatc tttacgatcg atgaggggtt acgggaaatc tttatgatgg
    36541 aaaactatcg agattcctta ctgaaaggac taatggatga agccgcaaaa attattcttg
    36601 cctattttga gaaaagaaag gtgaaggcag gtgtagtagc tacaatccac acctttggat
    36661 caaaactaga atttaatccg catgttcata tggttgtcac tatgggtggc ttaacaagag
    36721 atggaagttg ggaagactac gattatttac ctttttctat gttaagaaaa tactggaaaa
    36781 atgctgtatt gaaactaatt agacgaacgt taggtgagtg ggacaagcaa agagttcaat
    36841 caagattaca agctgcgtac aagaacaatg gagaagggtt ttacgtaaat gctcctaaaa
    36901 gaagcaggac aaatctaaag tcactactcc aatacatcag tcgttatatg aagcgtggcc
    36961 cgatcgcatt aagccgaatc ttaatgtatg atggcgacac tgtcatgttc aactatatgg
    37021 acaaacgaac gaatactaaa gagacgatga ccatgagtat agacgaattc atagctgcac
    37081 tgattcgcca tattcaaaat aagaatttca aaacgattcg tcgctatgga atctatagtc
    37141 gtagaatcaa aacattaatg aaaaaggtca tgaaggagta tcagaaacga gtaaaaaagc
    37201 tgtttatcaa tctgaatgag gccttaagac caaaatcctg ggaagaaaga ataaccgaag
    37261 aatttggtga aaatccctta gaatgttctt gttgcggtga gtactatgaa ttcgttggga
    37321 tgagtgtgcg caaaaatgga aggttagtta ttaaatatgc gaaagataac catgcaaagc
    37381 gatttatgcg agaggagaat cgaaaaattg accaaaaaga attcaggaaa cagtatgaag
    37441 aagaaaaaga aaaaactttt aaagcaattc gctgggattg gggacgccaa cgtgaaattt
    37501 atatgtctaa gttgtggtga aaaagaatca atcccaatgg atgtagtaaa atttttagat
    37561 gatgcagata ttgcaaatga tccgaacaat cctccccaat ttacctgtga aaaatgtggg
    37621 aaggagatgt atccggaata ttatagaaat gcccttggaa tagagtttaa gatcagtgat
    37681 cttcaataag aaggttaatc atacaaaaag tccaccggag aatgaattct ccggtggttt
    37741 tcttatgctc taattgcgtc aactggtatt agattttcat accaattatt gaaaagtcta
    37801 tttgaatata gtatgaaaga aaaattttac tagcatattt tatcttacga aaacttgata
    37861 aatcagcatt ttaagccgat agtaaaatta ctaaaagatt tattgttgac aaaggtaaaa
    37921 aaaccacctt accattgggt tgtggttata accagtttaa aagaaggaga agcccatgga
    37981 aaattctttt aaaaacaaag ctttgtatca tcaacttgta gatttattga agaagcggat
    38041 ggaaagcggc atgattcctc atgataagct gccatctgag cgggaattaa cagctcagta
    38101 cggagttagt cggacgacgg tccgtttagc tttgcaagag ctggaaaaca cgggatacat
    38161 ttatcggcgt catggaaaag ggacatttgt ctctgatatc aaaacagctg ctgcagattt
    38221 agctggtgcc tacagcttta ccgaacaaat gaaaagcctc ggcagacatc ctgagacgcg
    38281 aattttatcc tttgaaaaaa tggaagctga taaatttatc gcacaacgac tcaatcttcc
    38341 tttaggagaa gcagttttca aattgagtcg gctgcggatc gcggatcgag agcctttaat
    38401 gattgaagat agctatctgc ctgtcaaatt cttcttgtca ttagatgatc agctattaag
    38461 aagcaagccc ttgtacgatc ttttttcaga agattttaag caaacggtcc gtttagcaga
    38521 tgaagagctt tatgccagca tcgcttcaaa ggatgacgcg aaacagctga tgatccctga
    38581 aggagcacca gtcctgcatt tagtccgtca gacctacaat atgaaaaatg aaatcattga
    38641 atttactttg agcgtcgctc gcgcggatca atttcattat cagattcgtc atattcgaaa
    38701 tagttaggag aattaaagca tgtttacaat agaaaaagaa aaattggaac aaatgggagc
    38761 ggagatcacg acgcgtgaga ttcgccaaca gccggaactt tggaaagaaa cgattgacct
    38821 ttatcagtca gcccaagggg aattagaaaa ttttcttaca gaagtccaaa aacaagcaaa
    38881 gggtcagcgt acacgcgtaa ttttcaccgg tgcgggaacc tcccaatatg taggcgacac
    38941 gctggttcct tatttgcgca aacacggcga tcgtcaagcc ttcagctttg aaagtatcgg
    39001 aaccactgac atcgtggcgg agcctgaaga atatttaatc aaagaggaac cgaccttact
    39061 ggtatccttt gccagaagcg gaaacagtcc tgaaagcttg gcagcagttg aaatcgcaaa
    39121 tcaagtcgtg gatacaatcc atcatttatc aatcacctgt gcaaaagagg gaaaattggc
    39181 gcaaatcagc caagcagact ccaagagctt tttattctta atgcctgttc gttcgaatga
    39241 tgacggtttt gccatgactg gcagcttctc ctgtatgaca ctaggcgcgt tgctgacatt
    39301 tgatcaaaca gcactagcgg aaaagcaaaa ctatgtagaa acattgaacg ctttaggaaa
    39361 cgaagtgatc gcccgtgagc atgacatcga agaaattgtc gcacttgatt ttgaacgaat
    39421 tgtttatgtc ggttccggca gtttagcagg cttgaccaga gaagcacaat taaaaatcct
    39481 agaactgacc gctggaaaaa tcgcgacagt ctttgattca tcgatgggct ttagacacgg
    39541 accaaaatca tttatcaatg aaaaaactat tatgttcggt tttgtcaata atgatccata
    39601 cacgcgggat tacgatttag atatcttaga agaagttcac gaagatgaaa tcgcttccgg
    39661 tgtctttgct atcactcaac ccggaaaacg gaatttctct ggggatacgt tcgagtttgc
    39721 aactgggact tctttacttc cagatgccta tttagcacta ggctatgtca tggtagcaca
    39781 aactgtcgcg cttttaacat cggtgaaagt tgcgaataca cctgacacgc cttcaccaac
    39841 gggaacagtc aatcgagtgg taaaaggcgt aacgattcat gactataaat aggaattaac
    39901 tgggaggaag aaacatgctt acattaacaa caggtaaaaa agcggcgatg gaccgtttat
    39961 caacaaagga tggcattatc agtgccttag caattgatca acgtggggcg ttaaaaaaaa
    40021 tgatcaaagc gttaaatgtc gaaccaacgg ataagcatat tgagcatttt aaagaattgg
    40081 tatcgagcga gctgacacca tatgcgtctt cgatcttatt ggaccctgaa tacggtctgc
    40141 ctgcagcaaa agtacgtcat gcagatgcag gtctattgct ggcatatgaa aaaacaggct
    40201 acgatgcaac cacaccagga cgtttacctg atctattagc ggattggtcg gttttacgac
    40261 taaaagaaca aggtgccgat gctatcaagt ttttacttta ttatgatgtg gatgaagatc
    40321 ctgcgatcaa tcatcaaaag catgtctttg tcgaacggtt aggcagtgaa tgtgcagaag
    40381 aagatttgcc attttactta gaattggttt cttatgatgc gcaaatttca gatgctggtt
    40441 catttgacta tgccaaagtg aaaccgcaca aggtcaatga tatgatgaag gaattctcaa
    40501 aaccgcaata caaagtggat gttctaaaag tggaggtccc agtgaatatg aatttcgttg
    40561 aaggctttgg tactggtgaa atcgcttata caaaagaaga agcggcaaac tatttcttag
    40621 aacaaagcca agcaacggat ttaccattta ttttcttaag cgcaggtgtt tcaacggagc
    40681 tattccaaca aacattggta tttgctaaag aagctggctc caccttcaat ggtgtgctct
    40741 gtgggcgtgc cacctggaaa aatggtgtaa agccgtttat tgaatcaggt gaagctgctg
    40801 ctcgtgactg gctgcaaagc gaaggtcgtg aaaatatcga aagcttgaac aacatgttaa
    40861 aacaaacggc aagctcatgg catgacaaag ttcaagtcgc agaagaagaa gcggtgaact
    40921 aggaggcgag ctcgtgatag taacagtaac gatgaacccg tccattgata tttcttatcc
    40981 actggagaaa ctgaagctag acacggtcaa tcgaaccgat caggtgagta aaacagctgg
    41041 cggaaaagga cttaatgtca cgcgtgtcat tcatgatttg aagggcgatg ttttagcaac
    41101 gggtgtttta ggcggttttc atggcgctta tatctcggaa gaattaaaga aagcaggtat
    41161 caagcaggca tttacagaaa tccaagagga aagtcgagat tcaattgcga tcttgcatga
    41221 aggaaatcag acggaaatat tagaagctgg tccgacagtt tcagaagcgg aacagcaggc
    41281 ttttttggaa aattttcagg agttggttaa agaagccgag attgtcacca tttcaggcag
    41341 tctggctaaa gggctcccat tgaattttta tcaaaggctc gttcaattag cggaagaaca
    41401 agtggtaaaa gtccttgtgg atacctctgg tgaaagcctg aggcaggtgt taaccggtga
    41461 gcataaaccc tttctgatta agccaaacct tgaagagcta gaagctttat tgggtcagcc
    41521 gttttcaatt gatgacttag aagagctgca gtcagcttta gctcagcctt tatttactgg
    41581 tgttgagtgg attgttgtgt cactaggcaa agatggggcg cttgcaaaat atcgtgattc
    41641 tttctatcga gtaacgattc caacgattaa aacagttaat ccagtggggt caggtgatgc
    41701 tactatagct gggtttgcct atggcttatc acaaaaaatg agcgtaacag aactgctgaa
    41761 gctttgtatg gcagccggta tggccaatgc tcaagaagtg cgaacaggtc atgtcaatct
    41821 agcgaatgtg gacatgcatt ttgaagagat caacgtaaga aaggcttcgc gaactcgctc
    41881 agcttttgag caataagacc aaaatatttc taaattgcca agaaacacag tgatcgaaga
    41941 gaactgatgt tgattggtac ctacttggtg cttctcaaat ttcgaaatat ttttgcttat
    42001 tgccgaaaaa gctagttcgt gaagccggac atggatatgc ctgctgtaaa acgatttatt
    42061 catgtgaaaa ttttatactt ttttcatagt aaaaaagatc gagcaataag ctcgatctag
    42121 tcaggattaa ttgttttttg agaccagttc aattttgtaa aaattccatt ttttatagga
    42181 ttcaacatat tccagcattt gctgtgtatc ccttcgtttg gtcacacgga cttggagaac
    42241 agttggttca tcagcagaaa tctccagcag ctttgctgca tctgaaggag tcgggaactt
    42301 gatttcattt gtttcggtaa agtcttcttc gttcatatgg atattataat ctagcttaaa
    42361 gcgttgatag atggaattgt aatagctcag ttcttgataa ttaggattca catattgttc
    42421 cggcaaatag gtctgttgat agatatacgg agtttcttcg gctttgcgca agcgtttgat
    42481 gcagtaataa aatgctgtat caggcaattc gagcttactt aaataaacgg gatcatttcc
    42541 tcgtgtgatt gataagactt gtacttgatc attacttata ggaaacaact cgatatcgga
    42601 aaattcgact atttttcctt tacgggcgcg cgagacgaaa gaaccgcggc cttgatgtcg
    42661 aacaatgaat ccatccttga ctaaatcatt caacgcgcga atgacggtga ttgagctgac
    42721 actgaacatt tctgccaact cggcttccgt ataaaatttg tcgccatttt cgaatttgcc
    42781 agaaatgatt tgctgtttta gttcatcttt tatgatttgg tattttggga tgaccatagg
    42841 aacctccaaa caatgaatag gaattaaaag tttcattaga attttttgat tttgtggtta
    42901 tggcttgatt ttaacacatt ccactaaaat aaggagagtt gactttcagt atcgaataat
    42961 ttaatatatt aatatattaa aaacgctttc atttaaggag ggagcttttg aaaacatttg
    43021 agattaaaga agattttctt ttaaacggcg aggcctttaa gatcatgtca ggagcaatac
    43081 attattttcg gattgaccca gcggattggt atcactcact gtataacctg aaagctttag
    43141 gcttcaatac cgttgaaacg tatataccat ggaatttgca tgaaccaaaa aaaggtgagt
    43201 tccattttga aggaatacta gatttggaac gctttttatc aattgcaaag gaactcgagt
    43261 tatatgcgat cgtaagacca tcaccataca tttgtgcaga atgggagttt ggtggattcc
    43321 ccgcttggct actaaacgaa gacacacgca tccgaacaaa tgaaatcggt tatttaaaac
    43381 atgtggctga ttattatgat gtcctcataa agaaactggt tcctcatcag ttgtcaaatg
    43441 gcggaaatat tttgatgatc caaatcgaga atgaatatgg ttcatatgga gaagaaaaag
    43501 actatttacg ttcggttcga gatttgatga taaacagagg aatcacggtt ccgtttttca
    43561 cttcagatgg gccttggcgt gcgacactta gagcaggcag catgatagaa gaagatattt
    43621 tagttacggg caattttggt tcaaaggccg aagagaattt tgcatccatg cagagtttct
    43681 tcgatgaaca cggaaaaaag tggcccctga tgtgcatgga attttgggat ggctggttca
    43741 atcgctggaa ggaacctatt gttcaacgag atgccgagga gttggcggaa gcagttaagg
    43801 aagtcttaat tagaggcagt atcaatctat atatgtttca tgggggaacg aattttggtt
    43861 ttatgaatgg ctgctccgca cgaggagtca ttgatttgcc gcaaattact tcttatgatt
    43921 acggggctcc gctaaatgag cagggcaatc caaccgaaaa atatttcgca attcaaaaaa
    43981 tgattcatga tacgtttcct gagattcaac aaatggaacc gttgacaaag aacacaatgg
    44041 aagtaaaagg aattcattta agaaataaag tcagcttgtt ttcaacttta gacacgatca
    44101 gtcaaccggt gaaaacgaca tatccagaga cgatggaaat gctaggacaa aatactggct
    44161 acattctgta tcgcacatcg attaaaaagg acgcggaaga agaaagactg agagtcattg
    44221 atggtcgcga tcgtagtcag ctatttctaa atcaaaaatt acaagcgaca cagtatcaga
    44281 cgcaaatcgg cgaggatatc attgttccga tgactgaaga aaccaatcaa ttagacattt
    44341 tgattgaaaa tatggggcgg gttaattacg gacacaaatt atttgctgat acacaaaata
    44401 aggggattcg aacaggagtt atggctgatc tgcatttcct cactgattgg tcgcagtatt
    44461 gcttgccgct ggattcttgt gaggcagttg attattcaag agaatggcag ccagagcagc
    44521 caagttttta tcgctatgaa gtagtgcttg atgaagtgga agacagcttt atcgatctgt
    44581 cgaattttgg aaaaggtgtc gtttttgtca atcaagtaaa tatcggacga ttttgggaag
    44641 ttggcccaac actatcgctt tatattccta agggattact taaagaaggc aacaatgaaa
    44701 tcgtgatttt tgaaacagaa ggaacctttc aaccagagat tcaattggta aaaaaaccat
    44761 tatataaaga aatgaaagag ggataacaat gagtattatt ggagtaagaa ttgacggacg
    44821 tttaattcac ggacaggtag caaacttatg gacaacaaaa ctgaatatta cgcggatcat
    44881 ggtggtagat gatgaagtgg cacaaaatga tattgaaaaa agcggactga agctggctac
    44941 tccagcaggc gtgaagctaa gcgtgctgcc gattgaaaaa gccgctaaca atatcttagc
    45001 agggaaatat gattctcaac gtctattgat cattgcccgc aaacccgatc gtttattgaa
    45061 gctagttgag ttaggtgttc caattgaaga aatcaatgtt ggaaatatgt cgcaaacaga
    45121 tgaaacgcgt tcaattacta aatcaatcaa tgttgtcgat caggatgtag aagtattcaa
    45181 ccaattacat gctaaaggcg ttcgattgat cgcacaaatg gtaccaagtg ataaagcaga
    45241 agacttcatg aatctattag cgaaatagga ggataagtaa atggatatct tatggtggca
    45301 gatcttatta ttaacattat atgcagggta tcaaatttta gatgaattac aaatttattc
    45361 atcattgagt gcaccagtct ttgccggatt atttgccggc ctagtaatgg gcgatttaaa
    45421 agcaggactt attattggcg gtagtatgca attgaccgta ctaggtgtcg gtacatttgg
    45481 aggcgcatca aaaattgacg ctaactccgg aacgattcta gcaacagctt tttcagtagc
    45541 attgggaatg aatccagagc aagcgatcgc tgcaattgcg gtaccagttg ccagcttgat
    45601 gattcaatta gatattttgg ctcgttttgc caatacgtat ttcgctcatc ggattgataa
    45661 attagtcgaa gatatgaatt ataaaggcat tgaacgcaac ttcttgatgg gggccattcc
    45721 atggtcattt tctcgcatga ttccagtctt tttagcgtta gcatttggcg gaggcttagt
    45781 cgaaaaggtt gttgctgtct tgaatggtga tttgaaatgg ttaggtgacg gtctatctgt
    45841 agccggagca gttttaccag ctgtcgggtt tgcgatttta ttacgttact tgcctgtgaa
    45901 aaaacacttt ccttacttga tcctagggtt cacgttaaca gcgttactag gaacagtctt
    45961 tacgaatatg caggttttag gcactggtgt tgcgggtgtt gtgaagaatt tcgaaggcat
    46021 tttcaattca cttcctatgt tagccatcgc attgatcgga tttgctttag ctgcgatcag
    46081 ttataagaat ggacagatga ttccaagttc cccagcaccg aaagaagttg cttccaatga
    46141 ttcagatgaa ggagagattg aagatgacga aatctaatta taagttgacg aaggaagatt
    46201 ttaagcagat caatcgcaga agcttgttta ccttccaatt aggctggaac tatgaacgga
    46261 tgcaaggatc aggctatctt tatacaatct tgccgcaatt acgtaagatt tatggcgatg
    46321 acacgccgga gttaaaagaa attatgaaga ctcatacaca attttttaat acgtcaaact
    46381 tcttcaatac aatcgtgact gggattgact tggcgattga agaaaaagaa gggatcggcg
    46441 gaaaagacac tgtatcaggg atgaaggctg ggttaatggg tccctttgcg gcaattgggg
    46501 attcgatctt cgccgcattg attccaacga tttttggggc cttggcagcg aatatggcga
    46561 tcaatggaaa tccaactggt atcttcattt ggatcatcgc acaaatcgcg gtaatgatct
    46621 tccgttggaa acaactggaa ttcgcttatc gtgaaggaat ctctttagtt acaacgatgc
    46681 agcatcgctt aactgctttg acagacgcgg cgactttgct tggggtcttc atggttgggg
    46741 cgttagttgc caccatgatc aatgtaaaat tctcttgggc accgagcatt ggtgatgtga
    46801 cgttgaatat gcagaacaat cttgatatga tcttaccgcg cttattacca gcaggaatcg
    46861 ttgcagcgat ttattggatg ctaggtaaaa agaacatgac ttcaaccaag gcgatcttta
    46921 tcgtattagt agtctgtgtg gcattatcag cattaggtgt gatttctaaa taagttaggc
    46981 tgattccaat gaataatgag gagcgaacca atgggaaaac aattagtttt agtgagtcat
    47041 ggactctttt gtgaggaatt gaaaaagagt acggaaatga ttatgggacc gcaagaaagc
    47101 atccatacag tcagtttact tcccgcagag tcagcggaag attttcgcgc aaaatttgaa
    47161 gcagttattg cggatttaga tgattttgtc gtgctggctg atttaatggg cgggacacct
    47221 tgtaatgtag tctcgcggat gattttagaa gggcaagcga tcgaactata cgcaggaatg
    47281 aatatgccga tggtgattga tttcatcaat agtgaattga tcggtacaga gcttgcatta
    47341 gtcgaatctg cgacaagtaa tatttgccac gtgaatgaac ggatcatcgg tgacgatgat
    47401 gacgaggacg agtaaaatct catagaagat gatatagagg cgtcgtttat ttgtgaatag
    47461 gagctagttt gaaagtctaa aagactttcg aaccagctcc tttttctgtt ctgctattat
    47521 ggtatgattg aggagaaaag aaagaatggg agattagagt ggatttcaac gagaaactaa
    47581 agcaattacg tcaaaataag caatggacgc aggaagaatt agcagagaga ctatttatct
    47641 cacgaacagc agtttccaaa tgggagtcag gtcgcgggtt tcccagtatt gattccttaa
    47701 aagctatttc gcaggttttt gatatttcta ttgatgagtt gctatccaat agtgaattgc
    47761 tgtcaattgc agaaaatgag cagcaacagc agcggaaaaa ctttcaacat ttgcttttag
    47821 gtatttcaga ttgcatggtc ggcttattaa ttgttctgcc gatttttggt caagcacaag
    47881 ggaaccatat tgcgtttgtc tctttatggc aactttcgca ggaaacaatt atcttcaagc
    47941 ttattatttt ttcattcgtt attttaacaa tgctgttcgg catttttgaa ctcgcttttt
    48001 ctaggcgaga acaacgaatt attggatcgg tttctttgat tttatcgttg ttcggcgtac
    48061 tgcttttcat catgactaga catccatacc cggcaacgta tgtattaatg cttttggcag
    48121 tgaaggggat ttccctatta aatagccgtt gatacgcatc gtcacatcaa ggtgacggtg
    48181 cgcttctttt tgtttctggc agtctctgat acgttttatt tggatagctt ccaaataatt
    48241 gttaggagag gattagtcaa atgaaaatag caaagaagca attagaaaca gccataggat
    48301 tattgatcgt ctttatttta tacacgattt ctttatcctt gttcgatgta cagaaaatag
    48361 gtccgcagca ttcggaggtg ggcttttcta caattaatca atacgtattt cagaagatag
    48421 gtactagtga attttggtat caagtgacgg aaatcttagg gatttttcca ttgataatcg
    48481 tggggtattt tgctttacga ggatttttcc aattgtatac ccgcaagaag ctcttactag
    48541 tggacaagga aattcttgcg ctaggatttc tttatgctgg agtcgccgct tgctatgttc
    48601 tttttgaaaa agtcatcatc aattatcgac cgattttagt ggatggacag ctagaggcat
    48661 cctatccgtc aagtcatact tttctggcaa ttacagtctt actgtcagct ttttatgtat
    48721 taagaaagga aacaggaacg ggaaaagcaa tcatcgccta tgtgagcctg gtggtcatga
    48781 ttgcgctggt tatcggacgt tttttgtctg gagcccattg gggaaccgat atttttggtg
    48841 gaattttatt aggtctgaca cttgccagct gctaccttgc aggaattgaa agtagttcta
    48901 aacaaaaaaa agaacgttga aaactcaacg ttcttagaag agccacctgt cgggcttgaa
    48961 ccgacgacct cttccttacc atggaaacgc tctaccagct gagctaaggc ggcatagtta
    49021 tttaacacaa gatatagaat agcgaaaaca agcttatttg tcaactggtt aaacagaaaa
    49081 aaatgcggca ttagctgctg tgaattcttt atttataaac gagtcgtcgc ttacgagcct
    49141 gcgacgactt gtttatatag tttagagacg atatcattat atccctttgg ttgagtccag
    49201 acatttgaga gcagaataat gccattttga ccatcttttg aaaaatcaac aagggcttca
    49261 aaacgtgcct taactcctcg tgaatggtag ttatttgtca tgttatagat tccgctggcg
    49321 tatttttcac ctggatacga ttgccataat gcagcacgtt cttgtgttgt taaaaatttg
    49381 tcctgataaa gatcttgaaa atagctgtac aaatcctccc ccgacataaa cacattgcct
    49441 gttcctaatt catctgcgta agaagatacg gtcgtaggag cgtaaacagg gccggaggaa
    49501 ctttctgagt atgaaagagc ctgctgattg ttcgtttctg aatagaagct tgtttctttc
    49561 agcttcattg gttttcttaa aagtttatca aatagtgtgc tgtagtcggt atgatagact
    49621 tgctccaaaa ttccagctaa caaaacataa ttgaccggtt gataggagta actagaattc
    49681 gcagccacag tcgtttgacg aattgtctct gaaagtattt tttgtggatc agtagtgttc
    49741 aaggcggcaa ttttcttttc gtcgatacgt aacccagaac tcatattcag catatctttg
    49801 atagagattt tctcactatt agaaatttgc ggataaaagg tgctgagctt ttcctctagg
    49861 gaaattttac cagatttaac cgcctgcatg atcaaatagg cagtttgtcc cttttgaacg
    49921 gagccgatgc aatattgtgt atgaatcgta ttgtggattc ttctagcttg atctttccag
    49981 ccataagctt tattcaaaat cacctgtcca tgctgaaaaa ctaaaacagt accgctaaaa
    50041 tttttttcta ccaataactg ctcaatacca gcggacgtag cattttttgg ttcgattggt
    50101 tgctgattgg tcaaatcagt agttgttttc gttgcaggtg tgctgctttt tttcgttgcg
    50161 tgatgctcag gatagctgtg ttcagcatac attccgctga atgctaggag tattaaaaaa
    50221 agcggaaaaa caagtgttaa tttatttttc tttctttttt ggtgcttgtg ttttgacata
    50281 ataaatcctc taattctatt tgaaatcgtt ccatttttat ttcgataaaa attttcagca
    50341 gttccatcta atttttgaaa attaggattg catcatgaaa taaaaattga tattatagta
    50401 aagtattctt ccggcatagc tcagttggta gtagcgcatg actgttaatc atgatgtcgt
    50461 aggttcgagt cctactgccg gagttttaga gatgatcttt tgatcgtctc tattttttta
    50521 ttttacaaat gaatacagtt cgtcgttttt accaagaatg attgtttgcc caactttgag
    50581 attgtcaggt gatccttcag cggtttgtaa ggagaacgtt ccgttgaact tatcggatac
    50641 cgttataggt agctttaatt ctgatccttc ctcatctttg agaattgctg tttttcgttc
    50701 atcaaaataa acagtcttta ttaaataatt tttcgtagtg atctcagcag atttgtcttt
    50761 ttttgtagta gtaacagttt ctttagaatt agaggtattt tctacgacta ttccatcttt
    50821 ggcatttgag cttgtgttta tttgattgaa tattttcagc gacaagatac cgctaagaat
    50881 agtcaatata gaaacaagtg taattaatac tgataatttc ctttttttgt tcattttttc
    50941 ttaacttcct ttttgttttg attagttaga tattccttat ctaacaagcc tttttaggct
    51001 attaaatgag gataaacccc aaaaaaatat tgcaattatg acagtgcaat ggtactatta
    51061 ttatacaata aattttgcga aaggggtagg tctaaatcgc aaacaaaaag aaattgaacc
    51121 tagacaaata caacttgtac accgcaaggg aagcaagttt gattttgggt aaaggtagaa
    51181 attatgttac aaacataatc aactattatc caaatcgttt gcctaaaggt tcgttcaaga
    51241 aagtgggtga caaaacctat attataacgg aagaaggaat agaagcattg cgatcacaaa
    51301 cagaaaataa aaacaaaaag aaggaatgaa tatgaagaaa aattcgcttg gtatggtttt
    51361 atttgcatca gctgtacttg cggggttatc agtaccagta acctcacatg ctgatgaatg
    51421 gactgcaaac acaccggatc aaatccaaat tacaacagga caatcaagtt atgcgttcaa
    51481 aaaaggagat actatttggt caactgtaga gaagcttaaa agcttaggtt acaagactac
    51541 tgttgctgag tttgccgaat tgaacaatgt tgatttggca aaaggagaac aacggactat
    51601 cccaattgga cgaactttca acatcagtaa agatacatta acagttaagg aagcagatgg
    51661 cgaagtagtt agtcaaactg ttcaaaaaga taaacctgat cctgttgaaa atacggagca
    51721 agagaacaaa aaatccgaga ctgcaaaaga atcggaacca acagcaaaca cttctgataa
    51781 gacagaaaca agtgcttcaa gtgttgatgg agcaagttca tctaatacaa ataattctac
    51841 aagtgagaaa gaagcatcac agggaacaag tgaaagtagc actacggaaa ctgatactgg
    51901 aacatcaaca aataactcac aatcaacatc aaatgatgca aatgaatcaa ccagtacatc
    51961 ttctagtgat caatcacaaa caggttcgag tgatgaaact gacagttcta cttcaccaag
    52021 taaacccgaa caaccaacta atgttgtgct aggcgttcca tttattagtc aaggtaacac
    52081 aatgctttgc gaaggaacat ctttgctaga agcgttacat tataaaggtg ttgcaacaaa
    52141 tcaagattta atgacttttg ttaaatcaat gccactatct cctgataata atccaaataa
    52201 tggtttttct ggtgaatgga gacacaatgt ggatggaact tatcaaggta tgaatccggc
    52261 tcctgtagtt tcatggggtg ttgctaatgg cggaaatgtt gtagatattt ctggttcatc
    52321 ggtacaagga ttaaaagatg agattgtaaa tggaaatcct gtagtagcgt gggtaactta
    52381 tgcctttgaa cctgctcaac ataaatcaat gttttggggc gatgctattt ggaatcgaca
    52441 tgtagtagcc gttgatggat ttaaagacgg tttttaccat gttgtcgatc ctgtgtttgg
    52501 ggcaagttgg attaatgcag gatcatttga aacagcatat aacgtatctc aattagcggt
    52561 ttcggtacgt taataaaaga gattgtttat atactaagta gttaagtata gtctttattt
    52621 gtccttgctt aactacttag aaaacttgtt gctcatggtg ggtagaacta aaaggggtga
    52681 tgctatgaat actagagcgt tgaaacagct tgctttcaac gaaaaaagtg attaataggt
    52741 gtggtgattt taacttagga atgggcgcga aggtcattac cacaccgaca tatcgtggct
    52801 cattttcttc gcctaactgg tataaagaag gagtaacgag agatgaagca tgaaaaaacg
    52861 ataattttaa aatcaaaaat aatttattgt tttgcgactt tagtaatggt gttatctacg
    52921 cttataatgc ctttttcagc aataagagct gaagcagatg tcacaaaacc gacaagtgca
    52981 aaatttacag aaactggcgt aaaaacagac ggttatatta gggttaatat gccgaatcat
    53041 ccaaatgaat ggatgatttc aagtcaattt aaagattctc atggaaatat tggatattgt
    53101 atggattcag aattgccatc cccaacagga agtggagccg gaagcttgaa gtacaaggga
    53161 gctggcagtg atgagttcta tcgtatgttt aaaggtggtt ttccatcaaa aacagcaaag
    53221 gaactgggtg caggaaatga tacagaagca tggtatgcaa cacaattagt ttcatgggtt
    53281 ttagccggaa actttaaagt ttcacagatt gtatggtcac atccaaacca taccgccgca
    53341 gaaacagctc gtgtaaaaaa agcatttgaa aaaatttatg actatgctaa gaatggaaaa
    53401 gatacgccca acactgagtt ttctatcaca gcttctaaga cagctgacga aggaaaatat
    53461 cacactttca catataaaac agcatcaaat aagactggta atgcgaagct cacttttaca
    53521 tcagcaaaac cagctggtat gaagatttat gatgcagatg gtaaagaaat tactaacaac
    53581 actgtgaaat taaattcaag ttttactatt aaagtacctg tgactacacc aagtggtact
    53641 ttgtcattta aaggtactgc taatgttagc acaaccaatc cttttacttt tgatggacga
    53701 ggcgtgtatc aagatgccgt agttatgatc actacttcag aaacaaagga ctctaaatct
    53761 ttgagtgcta aatggacaag agctgttggt caggtaacag ttaagaaagt tgatcaagat
    53821 ggaaatgctt taaaaggagc ggagttcact ctaactgaca ataacaatgc taaatctgtt
    53881 aagacaaccg gagatgatgg gttagctacg tttgatttgc aacaaggctt aacatacagc
    53941 ttagaagaaa caaaagttcc tgaaggttat caaggttcat ttaaaaagga tggtattact
    54001 gttaataccg atggacaaaa atttagttac actgctacga acacaattaa aaaaggtaaa
    54061 gtaaaagtta aaaaggttga ccaagatgga aaaccattag ctaatgctga atttaccttg
    54121 acggatgatt catcccaaac acaagcagaa aaaacagatg aaaacggact tgcaagcttc
    54181 gatattgtag caaacaagac ctacagcctt gaagagaccg gagtaccaac tggttataca
    54241 ggcgcattca agcaagaagg aattaccgtt aaagatgatg gacaaacttt tgaatataca
    54301 gctacaaaca ctttgaaaaa aggtgtagta aaagttcata aagtcgatca agatggaaaa
    54361 cctttggcaa atgcagagtt cactttaacc gatgaaaaag gtgcaacaca agtagaaaaa
    54421 acagatgaaa atggacttgc aagcttcaat attgtagcaa acaagacgta tagtctagaa
    54481 gaaaccggag taccagtagg ttacacaggt gcatttaagc aagagggtat cagtgttaaa
    54541 gacgatgggc aaacttttga atatacagct acaaacactt tgaaaaaagg tgtagtaaaa
    54601 gttcataaag tcgatcaaga tggaaaacct ttagcagatg cagaattcac cttaacggat
    54661 gaaaaaggtg taaaagaagt taaaaagacg gatgcaactg gtctggctac gttcaacatt
    54721 attgcgaaca aaacttacaa cttagaagaa acaaaagtac caacaggtta cacaggcgca
    54781 ttcaaacaag aaggaattac cgtcaaagat gatggacaag tctttgaata tacagctaaa
    54841 aacactttga aaaaaggtgt gatcaaagtt cataaagtcg atgatcaagg gaaagcatta
    54901 gcaaacgcag aattcacttt gacggacgac aaaggtgtaa aagttgtaca aaaaacggac
    54961 agaaatggct tggcaacatt taatattgtt gccaacaaaa cgtacaaaat cgaagaaaca
    55021 caaaacccta atggttatac agggaaatgg tctaaagaag gcatcaccgt tgctgacgat
    55081 ggacaaacct ttgaatatac agtaattaat caccttgtac ctgaaacagt aagaacaggc
    55141 ggaatcggta catcagcctt ccttcttgta tttctaattg caggattgag tatggtgcta
    55201 ctgtattatc gagaacagca caaagcaaaa taaaaaagtg ttaatggaaa agaagtaaat
    55261 atgaaaaaag aaggctgacg tatgaaatca aaaaaaattt tttcaaattt aatgctattt
    55321 ggtactttgc taggagtggg attgggcgca agctcaatct cttctagcct tggactaggg
    55381 gggcaagtag catatgcaca acaaaactat aattatcaag gaactggaac gattcatatc
    55441 cataaagtaa caaatactaa tggggatggg aaccctgtct cagatattga taacaaaggg
    55501 aaagaaatag ctttaccaaa tggtgtaaaa cctcttgaag gcgttgagtt ctcttatgtg
    55561 aaacttacta aagatgaagc taaatccttg ggatggacgg atagtgatac tacaaaaggt
    55621 caacatattg atgatgctaa agcacgatta ttactaaaca aaaaatacag tgaagtaagt
    55681 agaatgaaga ctgattcaca agggaatata gacataccta tacaagtaaa tacagacgat
    55741 ttaacagata acttgtattt gattgttgaa acaggaacag tcaaaggtgt agttgaagaa
    55801 gcgtatccta tgattgttaa cgtacctgaa ctaaacggat cagatgatca atactttaat
    55861 tatgatgtac atgtctatcc taaaaactat ttccaattaa actcagcaga gcttgataaa
    55921 aaagacgaag atggaaaggc tcttgccgga actgtttttg aattgcgaaa agatgatgga
    55981 tctgatcagg ttgttggaac ttataaaaca gacagcacag gtaaattaac tgtagatggt
    56041 ttggaattag gtgactatta tttcctagaa accgatttgg gaacagatgc taataaaaca
    56101 acctatttac tagatggtaa aaaattcaaa tttagcgtta aacgtgggga gactgctaaa
    56161 gtagttcttg atgttaccaa ctacaaacga cctgtaatta ctaaggtaat tgataaagaa
    56221 accgttgata ctggcgaaga tgttcaatat acattgaaac catcaattcc tggtaatatt
    56281 ggtaattacg aaaaatatgt tgtcaaagat gttctaggtg cagagttaac ttatgattca
    56341 tcagaagtga tcgaaggaat gactttagat actgattaca gtatcgaacg tgacggacaa
    56401 acgacaaact atgtctttac tgaatcaggt atggataagc ttcagaaaca atttgatgca
    56461 ggggatcgct tctttacaat tttgatgaac gctcatacta atagtaaagc taaaatggat
    56521 acaccactta agaatgatgt ttcaacgatc tacaacaatg gatatgaacc cgaagacgaa
    56581 acaccagttg atcacgctta tacaatcatt ggtgatcacc aattcattaa aacagatgga
    56641 gatacaagca aagcattgag tggagcaaaa tttgtagtga agaacaaaat tgatccgaat
    56701 aaagttactt acctaaaaca agatccaaca acgaaatctg ttacttggat tgcagataaa
    56761 tctaaagcta ctgaattcgt ttccggatca gatggtaagt tccaaattga aggcttgcaa
    56821 tatacctatg atgtagattt tgataaacaa ggtaatccaa caatcacaga taaaaaaatc
    56881 aatgattatg ctcttgaaga agttgttgct ccttcaggat atacaccaac tagaaatgat
    56941 gttccatttg tggtatcgaa tgatgatgct tctagcgaag taacagacat caagaacctt
    57001 aaaacacctg aaacagttcg tacaggtgga attggaacag tagtatttct agtggttgca
    57061 ggtgtggcag gaacagggct atatgttgtc tacaaacgag aacaacacaa agcttaatga
    57121 aataaaattc cctagagtgt ttttggctct agggtttctt tttaaaaagt gtgtgaaaag
    57181 taggtatgag catgaaaaag aagaatatca agttgatcat cttaaaaatt gggatgttgc
    57241 tatgtttagg agtaggtcta tatcctgtaa ttactcaggc ttatacctac taccaaactc
    57301 aacaaacact aaactcctat aaggaaaaat atgatgaagc ttctgaaaag gagaatgaag
    57361 aagtcttcaa aagatattca gaagttaata ggaaacgaaa agacacagaa caaacctcag
    57421 tcacgattcc tgaagataat aacaatattc cgtcaaatgg aaatcttcag aaggataaat
    57481 taggtgaatt agtgggtgaa attcttatac caaagattaa tgtggatttg ccaatttatg
    57541 atggtgtaaa cgatttccaa ctatcagcag gagcaggaat attaaccgga actgattatc
    57601 caactggtgg gattggaaac cattctgtta tatcagctca ttcaggcatt cctaataaaa
    57661 aatattttac agatttagag ttgctcaaac ttggtgataa attttttatt gatatttcag
    57721 ggaaaaaact tgcttatcaa gtagatcgga taaaaacaat tctaccaacc gaatttgagg
    57781 atttgcttcc tgtggcagga aaagattatg taacacttat gacatgtaca cctgttggag
    57841 ataattctca taggttactc gttagagggg ttagcatacc ttaccaaaaa agtattgttg
    57901 agaaagaaaa gaagaaagaa gatttaaagg taaaggcgca gatgaactgg tatcctatcg
    57961 tagttgtagg ggttttatta ataatagctg tgatagtcat tattaaaaaa atagtagcaa
    58021 agagacgagg aatgaaaaat gaagaataaa atactacttt ttttgactct tatttgcact
    58081 ttggttttaa caatttatcc tgcaaatcag ctctatcatc aattcaaaac aaaagagaat
    58141 gtggcggaaa tccaagagaa aattgagaaa aaacaaactc cttcaaaaga ggaagtggca
    58201 aaaaaagtcg aacaaataaa atcgaacagc ggtaaccaag gattagacaa tactcagaaa
    58261 acagataaag gagtagacaa tactcaggaa acagacggtg gatcatttga tattcgtgaa
    58321 gctgaaggaa aggtcaatcc atacacagga gatgtttttt caaaaaatca aacgaaagat
    58381 tttgaaccat ctacctattc aggagcggtt ggttatgtct atattccaaa aataaatgtg
    58441 ctagagcttt tgtttctagg cgcttcacag gagcatttat atagaggtgt ggcacaaatg
    58501 agtgctacta gtctaccttt atcaggtaaa ggtcatcaaa cagtaatagc aggtcatcgt
    58561 ggcggttata cgtcaccaca atttctttat gttgatcaat tagtagccgg agaccacatt
    58621 tatatagatt atcttggtga aaaagcagtt tatacggttt tccgaacaga cgttattaga
    58681 aattacggtc agaattcaac actgactgat attcctgatt tagatatgtt aacactttat
    58741 acttgtcatc catatcctca gaactacgat cgtttattag ttagaagtct aagagatgaa
    58801 aaagcaaaat acatcacgcc acaagtaaca gttggcaata ccgcatacgc tgatgccatt
    58861 gatagcgagt ccgtttcaga taagacagaa actgttacat cttctaatga tttatttgaa
    58921 gatgttgatc gtgccaacaa ggaattagat ggaaataatg atcttaatat tccggaacaa
    58981 ggtagcgtag agatgcaaga cagaacgttt gctgaaaagg caagttcaat atttacagga
    59041 attaccaata aacatcagaa aatgctttta gtcatttgga ctgtaatagg agcattagca
    59101 agtctaaagg ttcttattct tttaatcaaa gagtttcgaa aagcataatg aagattataa
    59161 aaattgatag agtacagtaa aaagggattg atactattat tgatctcttt tttattttga
    59221 atagagctag attcactttt aaataaaatc aaaactgatc ttaattctaa agaaaaagtc
    59281 aagaaaaaaa tacaataaat ttttttatca gaatatttat cagaatatta ttagaaaaga
    59341 taaactcaaa agcttaattt aatagggtta ttggttgtat ttagaaataa tgtatggaaa
    59401 agctataaag caatagataa gatgtagaaa atcttatttg tgaatgaaaa acaagtcatc
    59461 gtaaaatatt aataggaggt gtagtaatgg tgggagtatc aaaaacagct ttagactcat
    59521 tagctaaact atttagtagc aggtttgatg gtgcagaatt tgttgaatat ctaagccaaa
    59581 acgaaagtgg aaaaactctg atcgaaacaa tgaaaaaaga ctatttgaat gaaaatgact
    59641 ttccgacatg gacgaatatt gaagatgcta catgggatgt agtatgtacg atatattctc
    59701 cttgggtaac gattgctgat tttgttttag ataaaattgg aggggataca taccctgatg
    59761 ccaaatctct tgctacaagt gactttaaaa cgttctatgg ttatctaata ggtctaatag
    59821 gcaatggaat agatttgaaa gttacgccaa aacaaacacc tgaagaaatt gaaaaagaaa
    59881 aaggagaggt tcaaatggct tatgcaaatg acagagaaaa agtaaaatta ttggaaggta
    59941 aattatctga agaagaactt ggaaaaatgg tgcaagaaat caatgaagac agcaactatt
    60001 ttcctgaatt gaaggtatat caaaatgacg aagatttctt taatgaaatg tttagtaata
    60061 gtccatggga agcagtaagt aaaacaaatt taggagaatg gaactttcaa gatgatctag
    60121 ttgcatttag caatgatggg tatttacgat catattcaga aagtgagtat agagctgaat
    60181 taaaaacgta tgaaacggat attctgatga gctatttaaa tctattagag agtggtcagg
    60241 gagagttaag agataaagtt gaagaactat taaaagaaga gctataggga ttatttcaac
    60301 ataaacacaa gcagaaaact accaaacaaa acgtaccatg caaaaagtcg gttaaaccgg
    60361 ctttttgctc tattatgaga ggagatcaaa ccatgagtgc aacaaccgat atggctttag
    60421 aagcagtaat aaaagataat acaggaaatg tcgaaaatgt agaagacttt agcgatattg
    60481 caatcaatct ttcagcatgg atttcagctg taggagaaga aaatatcgaa tttgagatca
    60541 agaatatgga tgacttaaaa gcaaaatttc cttttattgc atcgaaacta agtcaagttg
    60601 ccgaggataa atcgtggaat gaattagtta gtttttccga aaaaatttat gatattacgc
    60661 aagaagatga gtgtgtttca tgggaaatga ataatcaata caagaaaatt gacgctttcg
    60721 tcaaatcacg tatagaagga acagcttttg agtttgaagg tatagatacc gcagataatt
    60781 ggttaaataa agaatccttt attaaaagta tagcggatga tcttgaaaaa caatggtcta
    60841 aggaagacta tgcagagtac ctaaaaacag aaagagatac agaagtgaaa gaaaaactca
    60901 ctgaggtatg tttggatgaa catattgatc ccaatatcgt aaaacaagaa gactatgaag
    60961 tggttattga taaagttcct actgattttg aggaagttgt aaagtatata gttgaagaag
    61021 cattatcgca atactcttca gatgaggaag tggacgaaga aactgttcgt accagagttt
    61081 ggcaactggt ttttgatgac aaagattata aatatttgag tgatcaaaac tcggttaatt
    61141 ggagtgtacg attattaatt gatcaaaatg atattgaata gagctgaaaa gctctattca
    61201 gattgtagac aaaaaggagt tggtaattaa gccactcctt tttgttagtc tttgcataat
    61261 tttgaaataa aaagccatag gcttttttgt tttccatagc catgtggcta gtttttttaa
    61321 attcatggca gcaaacgtaa gcatcgtgtg cgtggcgact ttttcaagac ctcgatattt
    61381 cgtccaacgc ataccatgct tttcttttgc atctgcaaat attcgttcaa tggtttgttt
    61441 tctctttttg taaatttctc tattcaacgc cgtatggcgt tggtgttcaa gttcatccat
    61501 aagatcagcc caaatatgtc gagtcactat tttttgatgt tttgtactca aagtacaatt
    61561 ttcaagtaat ggacaactca cacagaattt tggatttgat ttataggttc gataaccatc
    61621 acgagtgata gttgaaaata acaacggttg attattggga cataaatagc agtcaaaata
    61681 ggcatcataa acaaagtctt ttttacgaaa cattcctttc actccatgag gtgcagtata
    61741 tggaagaatc gggtagagtt tcaagtgtga cagaaaatga acaaatttag gcgtcttata
    61801 tcctgcatca gcaaccacac gctttatatt tggaaaagct cttttcgact gtttaaccag
    61861 atcgattgcg acttggctgt catgcacatt tcctggtgtg attaatgtag ataagataaa
    61921 accgttatct tcacaggaag tatgtgcaga ataagcaaat tgtttttctc gttcaccttt
    61981 aacatagtaa ccactttctg gatctgaatg acttattttt tgaagactca actcactttc
    62041 tgtgtcccat gtaaaaggac gttttcctac agcaatacgt tctttattta tttcatcttc
    62101 taattcatct tgataagctt ttgcttgacc gtaggtcatc tctttcgtga acttatgttt
    62161 attggcattt gctttgatat gagtagaatc aatataaagg ttgtcttccg taacgaagcc
    62221 agcttttaca gcttgttcta gaatatgaga gaaaatatct tcaaataaag ttgtttctct
    62281 aaatcttcga acatagtttt taccaaaagt agagaagtgt gggataggat cctcgaatga
    62341 ataacctaaa aaccaacggt aagcaacatt tgtttcaacg tctttaattg tctgtctcat
    62401 cgaacggata ccaaataaat attggataaa tactaattta attaagacca ctggatcaat
    62461 actgggacga ccataggttg aatacgtaga ttctacaatg ggataaatga aatcaaactg
    62521 aatcgcagca tcaatttttc gaactaagtg atctttaggt acaagatcat caattgttaa
    62581 catagcaaat tgatttctac cttcaatcga ttgttttctc atcattagaa tcactcccag
    62641 aatagtttat acaattagta taaaacaaaa aactgcaaac aacactccaa atttaggagt
    62701 ttgtctacag tctgaataga gctgaaaagc tctatttttt ttgataaaaa aactagctat
    62761 tttattaaaa ataatttggt tcaaaattta tttttttaac ttgataattt tttgccatcc
    62821 ttttttaaat tggctatata tcaaggttta tagtgggaat aaataaaaat acatttgaca
    62881 aaatttacaa tatagtttat tatatattta tcttattatg ataacacaat aaaaggaatg
    62941 gtggtatgaa aaagaagaag tttagccgat cgttgttagg aattttggtt ttagttgcgg
    63001 ttggtcttag tggcaagggt tactttcaga ataacagtac tcaggaacat gattttcaga
    63061 tcaaaagtag tgttcaggta ggtaataaag cagacagtga atcaaaagaa tttttaggga
    63121 tacgttatga tccaaacaaa tatccaaata atatcgtaaa cattaatgat gggaaatata
    63181 cactgacaaa agaagaccat gaagcattat cagaaaaagg cagtcaaacc ttttgggtaa
    63241 attatgcaga tttagatcaa cttggaagag caggagatgt tgaagcgttg atcacctatg
    63301 atgctgtaaa ttctcactca tctaaaaatg tggaacgtcc atctttcaaa agttctgtcc
    63361 atattgcagg agaatacaag gatggagtat ttgatcaaga gagagatact tgggtcggca
    63421 aagattcaaa caatgaaatc actcagctag aaggctataa aggttatctc tataacaaaa
    63481 gtcattcatt agcatggtcg ctaggaggag atatggaggt acacaattta acacttggaa
    63541 cgagagcgca aaatgttggg aaaaatgatc agaatggagg gatggcttac tcagaaacga
    63601 ttgtacgtga tgcaatctat aaaaataaga atgaaaaagt attgtataaa gttgatccaa
    63661 tttataaagg gaatgaatta gttcctcgtg gttctcatgt cgaagctttc tcagttaacg
    63721 ataatggaaa aacggtaaac cttaatgttt atgtatttaa caatcaaaaa ggaatcaaca
    63781 tcaactatca aaatggtact tgggtaagag attagaaatt gagaaggtga agaattggaa
    63841 acaataagca tcaatggatt agataaatca gttgcaaatc gaataaaaaa aggaaatggc
    63901 tactatcttc tgaagaaggg taaatattca gttgctagag agttagaaac aatgagtatc
    63961 gtgtatgtag ctaagaatca ttttgacgta gaacaggcta tttttgatcc agattctgaa
    64021 atagggaaat gtgttgaatt atcagagaaa actgttagta caaaaggggc gatgatcatt
    64081 gagagagaaa tgttagacga aatcagagta atcattccta aagatacgca gatgtgtgag
    64141 gacagcataa gtgacgatga accaaaatca gaaagaaaat aaggagatat tcagatgagc
    64201 gaaaaatcca ttgaattaaa ggaatataag cgaagcgatg gagaaaaata ttatcctgta
    64261 gccagttttt ctaaatcagt atatctggtt ggacgtgcat tggtagttgg tgcaattggc
    64321 atatatattt tgcattgggt aacaaaggtt gtacaactgc ttgtagatac cttagtaagt
    64381 attcttgtct cgttaaatga tgttaacgga acagatgatt taggattaaa agagatgttt
    64441 aaagagttac tcaatgcgtt ttttcccaat tatttaagtt attcatataa tgtacaaagc
    64501 ttttttgcaa agctacactt ggtagacatc tctattttag tattagaagc aggaacggta
    64561 ttctttgttg gatatttggt tactttgatg ttcaggcatc actatggaga acaaagacca
    64621 ttttttgatg atatggaaag tagaaggttg aaaagagaag ctctagaagc tatggatgtg
    64681 aagtatgatc caaacaagat tataggagat gaaacgaaca acaaaaaaag aaaacgaaac
    64741 aaaacgcaat tagaatccga tgtgctatca acgcttaaaa atatcaaaat ttctgttcat
    64801 acaagacgtg atctaagtgt caatgaagat attcgagaat atatcgtaaa aatcccgcaa
    64861 ccaaaaggga agaaagttag agaaacagtt ttacgacaaa ttcaagattt agggtcgatc
    64921 ctgacaagag caacaagcgg acgagccaaa tttggtgaaa aagaagatga agtttcaggc
    64981 gattatttca ttttccgagc atcagtaaat attgaaagag aacgtaagga aagagtaagt
    65041 accaaaaaca aagaaacgga aagagcaaca tcttcaatcg cagtttcaaa ttcacaattt
    65101 tcttttccaa tcaatctctt tgccgataat tccaaaaata tccaaaacca aaccgaaaaa
    65161 gctagaaaat atgccgaaac tcaaaagcaa tctttagaac tttatctatc ttctgctgac
    65221 gtacctgcaa gtctaacaga tatgcacgtt gggaatacat ctattgaata tttgtttact
    65281 ttatctcgta ccagaaaaat tcaactaagc tcaatgaaag aagaaattga aacttacttg
    65341 catatatcag gtgtaatcgt gcggatcaac gcagggcgta ttcaaattac tttaccatta
    65401 ggagaaaatg atcgtattcc aattgatgta ccatcaatga tcaatagcgt gttttagaag
    65461 acatcacaaa tagaaacaga aaatacaaac taccagttca caaacagaaa agtaccgaga
    65521 aaagtgagga atagaaatgg ctatgaaatt attagagaaa gtcaaaaaga gagccgaaaa
    65581 agctgaatct attttgctag ataaagaacc taatataaag cttaatggaa aattcagtgt
    65641 caatatgttg aacacaaagg ctaaagaccc aacagatgct atttttggaa ttaagcctga
    65701 tggcacaatt gctcattttt gcatcagcga aatgccacac atgttggttg caggaacgac
    65761 aggatcaggg aaatcagtat tactgaatga aattcttgtt acagtaatgt gtcactcaac
    65821 gcctgatgaa ttaaaaatag gaattgtaga cccaaaaagg gttgaatttg gaagatacaa
    65881 aaaattgccg ttcatgttgg ctgatccaat tacagatatg gatgaagctt atgatttttt
    65941 tgaatatctt gtgatcttga tgcatgaacg ttacaaactg atggaaaaag cagggttaca
    66001 aaacatcacg ctatataacg aatatgccga aaaaaatgga ttagatagat ttccctatgt
    66061 gatcttatta gttgatgaat attcacagtt ggttggaaca cataaagaag tagaaggttt
    66121 gattgttcaa ttaggacaaa tggcaagggc agcaggtatt catgttatct tagcaacaca
    66181 atctcctcga tcaacagttg tcactggtat tatcaaagcc aattttccgt cacgtgtttg
    66241 ccttatggta gcaagtgatt tagaaagtag gattgtatta gatgaaggcg gtggagaaag
    66301 tctaagtcca aagggagata tgcttattaa gcttgttgat ggaagtatgg ttagagcgca
    66361 gggagcttac atcagtaaca aagaaattga aacaatcttc aatcacctta gaaatactat
    66421 gccagaacca gaatatgttg attaccgagc aatcgtagct gaaactcgtg gtgagggcgg
    66481 tgaagacgag gattttggtg gaattggtaa agctcctgta agaaaatctg ctaaaagaaa
    66541 tttgaacaca cctttagcaa atccatcatc taaagagcca tcaattgaaa agaagagtgc
    66601 gtttgctatt aagcttgaaa agaacaaaga agaaaaagtc gagcagggag ctaaaacact
    66661 agaaaaactg caagcagaaa aactagaaaa agttttaagg gcattaggaa aagctgatcc
    66721 tgaaccgcaa acctcaaaca acacgaataa taaacagccg attgcatcta aaaccaaacc
    66781 taaagctaat gatccaaaag gctcagaaaa cgtagtgatc acaactgata aatctgaaaa
    66841 gaaacaaata aatggaagta cttcacctat catgcaaaaa atgttaaaag caaaaaaaca
    66901 ggtgcataaa tgatcatcgt cagttctttt ttaagatggc ttactccata taaatataca
    66961 gatgaagtag ttgtgaaacg agcgaagaaa agagataaaa aagcggtact aactcctaaa
    67021 cagatgcttg atcatggcat tttaggggtg aaggttttag aagtgaataa accgtttgaa
    67081 tcaaatagtg caagagaaaa gttgcttgga gctgaagccg atgtcgcata tttttaccat
    67141 gacaaaagca agcatcaaat agctattaaa ttcaatccaa aatcggcatg gcggtatcaa
    67201 gcaagagatg acttgaaacg taggaaactt agaccaatgc tctatccaga aggaaaagaa
    67261 gcatttgata gaacccacat cgttcccatt ggttttcatg gtacagaatc agataaccgc
    67321 ctattagtag gttggaacag caatcaaaat agagttcaga tcaataaatt tgagaagaaa
    67381 gtaaggaaat tcaacgatcg aaaaacgatc ctatggtttg cagatatttg taaacagccg
    67441 gatggaacag caaagtggga agcggtgata tttgacgaaa atggtaaaaa agtaatgtct
    67501 gaaacatggc atgataaagc taaatttgtt tggcagtagc agtagaggtg aaaaagattg
    67561 ctagaacttt ttgaagcaaa tagaacaggc tttaatcaaa aattagaagt gggagaaact
    67621 atagaatata aagataaaaa ctatattatt atcggaatct ataacacgag aattaacaga
    67681 ataggtgatc cacgtataac cagtgacttg gtttgtcaat ctgttaacta ttcacctgat
    67741 ctgacaagca ggtataagaa atacgtgtta ttagaatata gacacaagat tactgatgaa
    67801 attggtgtaa acaacacacg aaacatattt aagatcggaa cagtgattcc ttatagtaac
    67861 aacgaagaaa aaatatttta tcagatttac ggaatagaaa agtttgaata tgaacatgtc
    67921 gatctgctag tgacgtacca aatgcgttta atagaacctt ggtcacaggc agaaattgat
    67981 aaagcagtaa aattgaaccg attatcaaaa tttaacgtat taggaaatgc cttttaaaaa
    68041 tcgcaataca caaacagaaa aataccaaaa aattagcaat gaacgtaggt aagaacatga
    68101 caataaataa taataaccct aaaaaatata atgctcttgt ccaatgctat atcgaaaaca
    68161 aaattacaat gcaagaagtc gctgatgaat taggcaaatc aaagagccta gtatcacacg
    68221 attttaagca caatgttttt ccgaacccga ttgagctgag gaaaaaattt caaaagagag
    68281 tttatcaaga aataggtaag tggattgatg aagggaatgc aattgaccct ttaattgaaa
    68341 aatatccttt tttaaaaagc aaaaataaaa ttcaaaggtt aattcgtcaa ggcgatattc
    68401 aagctaaaga acctgttttg acaaccaatg atttggctaa aataaatctt cataaacaaa
    68461 ttattgaaga ctttgaaaaa aatctttcaa caactgaaat tttaaaaaaa tacaatattc
    68521 cgagaggaaa gctaacatcg actcttttta gagaatatgg agaatcggca gttactaaag
    68581 caaaggaagt agcgaatgag agaaaaaaac aaaaatagta gtcgatacct agtagcgact
    68641 gtagtttttg tttgtgtatt gattttcctg tttgattttt tgcagattgg aaaaagcata
    68701 attggaaata cattgagtgc aaaggaaatg gttgctttag gtggtttgta tgaaggacac
    68761 ttgttcccga atatattcat ttctatcgtt tctcatatta acttgtacca tttaatttct
    68821 aatttattgt tcttagtagt tcttgaagaa gcactgaatg atcagtatga gtggttaaca
    68881 ttattgatcg ttttaatcat atcaggattt ctaggaagct tagttccttt tctgctacac
    68941 agcaacatcg taagtatggg gcttagtgga ggtatttttg gatggattgc tttatttgcg
    69001 attgcataca tccattttga tagcaagaaa catttattac taagtgtttt tgtattattg
    69061 ataatcggca ttttactggt atctactttt gaatcaggcg agacaaacgt cttgtcacat
    69121 gtaatcggat ttgtctgtgg gatgatcttg ggatttattc taaagaacgt ttcattgatc
    69181 aaacaaaaga attaaaaggg agtgctaaaa atgccaaaaa aaaaagaaaa gaaaattcca
    69241 gtgtttttgt ctgtctcaga aatgttatca cttcaaatac tgttaagaaa aaagattgaa
    69301 acaatagacg aagaagttag aaataaaagg gctatgtacg aacaacgtga agcgctaaga
    69361 gaacgaatcc actattttga tgatatacac actaaaatct atgaagcacg tacaaatcac
    69421 gaagacgaaa gcaaattagg attagctcaa caacgaatat ttgaatggct gaatacgaat
    69481 actgagcaag aaccgttaag agcaattagt aatctttttg aatttggaac gaagcattgg
    69541 tttaacgctg tagaaaagga tgctgactta caagaagcgt tcgatacact aagcgaggat
    69601 agcaaatcca tgcgagactt attgatcact tatctaaatg agcatgaatt tgaacagacg
    69661 aaagttaaaa agaaaaataa aaaatagaaa gttgtgatgt atcatgctgt ttaccttatt
    69721 aggttattta tgtttagttc ttgctttttt tggagcaata gctatatttg tcggtcagtt
    69781 tcaagcaaat aatccgataa tgcgtaacat aggcattgga attgttatca tatccttgat
    69841 tgtatttggt gccacaaaga tttttgggag taatgatcag cagtttggta tttctggagt
    69901 tgataatagt tatgctccag attcattggg aagagtagtg atagatggaa cgtttgagaa
    69961 tgtaacgagc tacaaaaatg tttcattgac agtgaaggaa gatggcaaga aagcatcaga
    70021 cgacgttctc gctactatta agccgtctca atcacaattt gaagtgtttt atacagttaa
    70081 agagaatagc cctgtacaca agctgacatt ggtttttaac gttgatggag aagaatacta
    70141 taaagatgta aaaataaata aaacatcaac gaaaaagatt atcgaatcag cgaaaaaaga
    70201 agtagctaca gaagaaagta caactgaatc aagttctact gtcgaagcgg aactaccaga
    70261 taaaattgat tttgatcctg aaaaagtcaa atcgtttgaa tctgtttctg gttctatggc
    70321 agatcggttt aacactgaag ttttcaaagc tatcaaaact gttaaattgg atactgaaaa
    70381 gcaaatgatt aatgttacct tattcaatgc agttgaatct atggatcagg ataaaaaagt
    70441 tacggttgca agagaactag ggaaaagagt aattgggttg tatcgaggta cggcaaaacc
    70501 agattcagac ggttcagatt tgccagttca cgtagtttat gaagacggta aagtttttgg
    70561 agactctaca gcaaatgaag cactaacgat taaattagct aaatagccgg aaaattataa
    70621 taaacaagtg gtgtcacacc accatcgcat aggtgtgaca ccttggagat gattactgat
    70681 ggtagtaaat aaagaaaaag taagaaagta tgttacttta aaaatagctt ctgttgaata
    70741 tttagaaaag cgagctaaag aagaagaaaa aacaagaggt aagaaggtaa cagtttcaga
    70801 gttgttagaa gaattaattg agagtgacca aacaataaga cgtgcattta ccaataggtc
    70861 tgttaaaagt tagggtgata ctatctttaa tttcaaccaa atttctaata tatgatgaat
    70921 agtttccttg tacaaaatat ctaattaaga gataaaagtt aggaggattc attcaaaatg
    70981 attatccaaa agtttgactg gaaaatgaaa ttaggaatta gtcttgtaat attgggattt
    71041 attatttttt tggggataaa agcacaaaaa aatcaatcta cttttgaaac tatgtcttct
    71101 caaattattg aggaatgttc caaaatttat tattgtgaga acaaaactga agaatctaat
    71161 ggcttttatt atatcgatca accacatgat gttgttataa aaatggagtc acatgaagta
    71221 aacgaatgga ttcaaagaag tactaatgta tcaaaaaagt tagaaagata ttctcaaacg
    71281 tttttaagta aagtcatttt ttcaaattgc aaaaataaag aaacgtctca aagagtagct
    71341 agttctttag aaaatttaaa attttctgtt tcaaaaaaag agaaatttgt agatttacga
    71401 aaataaacta tcgaaagtag tatgattatg atcttaaaat atcatcttaa gagaagaatt
    71461 acgattgttt ataggattta caaaatgaat aagtttgaag agtgatttgg tcgcagacta
    71521 gatcactctt tttgtataaa aaaactttac acttattttt gagtgtgtta agatttttta
    71581 tatagagtga cggtttcttg tcagagtgaa tgataaccat caatattgga ggaataataa
    71641 gtggaaaaca ataatgatat tagatatttt agcattgggg aaagagttac aacagtaagt
    71701 gaattatcaa aggattatag agataaagaa ggaacgatta tttctcttaa aaagaatcga
    71761 agaggtgttt ggcaatatgt tgttgattta ggggatggcg ttacagttga gtgtaaagat
    71821 agtcaactga tcagaaatga tggcagtcat tccattgaaa aagcaattct tgtattccca
    71881 aaagtatcaa gcaagattat gaatgactgg ttgcttggaa aatttggtga gtacaataaa
    71941 aaagaaatcg cagaagtgat cggcaaatct tatccaacag tattagggta tctaaaaaag
    72001 ataacgaaca aagaagcgaa agttgaggat gttttaacag taagagaact tcagtcatta
    72061 atcgaatatc ggaataaaca aataacaaat cctgagtacc ttaaaaaaga agatggtcta
    72121 ttgaaacaat tggaacaggt aaataaaatc cggaaaatgc aaaaggtagc tcctttaagc
    72181 ctagataact ttaaaaaaat ctatttgaaa gagatcgaaa aagactaatg tggagtgtca
    72241 ctttaccgtt tcaacctgta tctgcaccaa gaccaagtgc aagaaggaat gttgctgatg
    72301 caactaatga cgtagcagag aaaaggattt caacctatta tgataaaaag tatctcgatt
    72361 atttgaaaaa aataaaaagc tttatcgaag atcaaggttt gttagatgat gaattttact
    72421 cgatcgtaaa tgatccgatg ggtgcaatta tggaagtgga cttttactat cagataccaa
    72481 aaagctataa aaaagtctat aacattatga agacgacagc gccagattta gataatttag
    72541 taaaaagtgc tatggatggt attttcaaca tctcagctat acgagatagc catatcacag
    72601 ggttaattgc ttttaaatac aatgtggcaa acgaaggaaa aacagttgtg aggatcaagc
    72661 gatattcaga atttgagtgg gatacttctg aaggattgaa cggagatatt tgggaagcca
    72721 catttgattt caaaccagta gcaacgccaa gaccaaagtc taaatttaga ggaaatggga
    72781 ttatcactta ctatccaaaa gagtataacg actatttgga aaatatcaag aatacgctta
    72841 aagagaaaga tttggtaaat gatcaactga aaaaggtaat gaatgctcct atgggggtta
    72901 tagctcagat agattatttt taccaagtga gaaaagataa gaaaaagctt gattcactga
    72961 tgcgtacttc acagccggat attgataact tagtcaaagg aacattggac ggaattttta
    73021 acaaggaaat tggcatcaaa gatagcaggg tggtaggttt aatagctttt aaatacaata
    73081 cttttgaaaa gtcgaaaaca aacgtgcgac tacaggagat gggctgatga ataataacga
    73141 aaaaattctt catgtacttg atagctttga aacaattcaa gaggaactaa agaaatatcg
    73201 agatgttttg gaacaaagat atgattttgt caatcagcaa aagagtaatc acatggattt
    73261 cattctcaat atgaatgact tgaagaagaa attagttgaa cgaaaagaac aagaaaagtt
    73321 gatcaaagct tactttgaac tcggtgaaaa agaagttaaa aaggcaatgg aactgaatga
    73381 agatcgcagg gttttagatc agctgttaga acaattattg gtgatgtttc aaaaaggacg
    73441 aatagatgag gatttaattg aagaagggtt gagaaagtat cctgcaaact caggtatcgg
    73501 aatagtgctg aaagcgattg atgaagaaga aattgaagct ttcataccgc cagaggattt
    73561 tgaatcggca atggaatata taaaatatta tagccaaggg atcactgctt ttagagagtt
    73621 tgatcctgaa gatgttattc atgacttgaa caacctaaaa gaatggtgtg aaagttatgg
    73681 agtcgatgat tccggattgg actacttgat cagtattatg gaaatcgaag aagagatgcc
    73741 ggataagcct gatccaacag atattttaga attgatccat gaagctagaa atccaattgc
    73801 ctatatttct agaggatata ctgtattgga atactataag ccttatatat cagcgatgaa
    73861 ccatttaaga cgtgtattaa gggaaaaacg tgaataccgc tcagtgttga atgcaacgaa
    73921 tagattagaa aaagctgttt cagagctaga tgcttattat cgtgaacatt acctgcaagc
    73981 aggtggtatg ccaagaaata cgaaagcaaa tatcagtagg tatataaaaa aagctgagta
    74041 ggcggagtta gcccataaaa tggcaaaagg taacctgaaa ggggcatttt gaatgaaaag
    74101 ggatgttttt gaattgtacg tattagaacg tctagaagac ggcatgatgg cacaagagat
    74161 aattgatgaa attgatgata tgatcagcag atttggtcaa ttggagttga atgatggaaa
    74221 caaaaattcg gtagtgctaa aacaattttg gttgaacaat ttttcgtata aggattttat
    74281 caaagaaaag gcaaatacat tgtactgact aaattcacga ggagcagtga tgagagctta
    74341 ttgctaagag cagttaggct cttttttgtt tgtgtaaaat tatttgtttt ataatacaca
    74401 tttatacaca aaaaaatatt gacagatagt acacaaatgt ggtaggatat atttgtaagc
    74461 aagttagatt aacaagttaa aggaagagca gttatgaaaa aagaagaact aatagatata
    74521 tttcaaattg ttgaacgagc aaataatatg ggaattatgt tttttgatcg tatttcttta
    74581 aagatg
//
LOCUS       DBBGRF010000006        69335 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000006 DBBGRF010000000
VERSION     DBBGRF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 69335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.006"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            212..604
                     /locus_tag="ACIZD4_000445"
     CDS             212..604
                     /locus_tag="ACIZD4_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC5989405.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACIZD4_000446"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACIZD4_000446"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGC5989406.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACIZD4_000447"
     CDS             2698..2943
                     /locus_tag="ACIZD4_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989407.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3165..4775
                     /locus_tag="ACIZD4_000448"
     CDS             3165..4775
                     /locus_tag="ACIZD4_000448"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGC5989408.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4752..4964)
                     /locus_tag="ACIZD4_000449"
     CDS             complement(4752..4964)
                     /locus_tag="ACIZD4_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989409.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5067..5936
                     /locus_tag="ACIZD4_000450"
     CDS             5067..5936
                     /locus_tag="ACIZD4_000450"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGC5989410.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="ACIZD4_000451"
     CDS             6101..7372
                     /locus_tag="ACIZD4_000451"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGC5989411.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="ACIZD4_000452"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="ACIZD4_000452"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HGC5989412.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="ACIZD4_000453"
     CDS             8763..9026
                     /locus_tag="ACIZD4_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGC5989413.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="ACIZD4_000454"
     CDS             9471..9920
                     /locus_tag="ACIZD4_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC5989414.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="ACIZD4_000455"
     CDS             9977..11395
                     /locus_tag="ACIZD4_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HGC5989415.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="ACIZD4_000456"
     CDS             11395..12255
                     /locus_tag="ACIZD4_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HGC5989416.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="ACIZD4_000457"
     CDS             12429..13202
                     /locus_tag="ACIZD4_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC5989417.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="ACIZD4_000458"
     CDS             13349..13714
                     /locus_tag="ACIZD4_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HGC5989418.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="ACIZD4_000459"
     CDS             complement(13862..15070)
                     /locus_tag="ACIZD4_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5989419.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="ACIZD4_000460"
     CDS             complement(15089..15367)
                     /locus_tag="ACIZD4_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989420.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="ACIZD4_000461"
     CDS             15560..16216
                     /locus_tag="ACIZD4_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC5989421.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="ACIZD4_000462"
     CDS             complement(16658..17455)
                     /locus_tag="ACIZD4_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HGC5989422.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="ACIZD4_000463"
     CDS             complement(17452..18636)
                     /locus_tag="ACIZD4_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HGC5989423.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="ACIZD4_000464"
     CDS             complement(18661..19908)
                     /locus_tag="ACIZD4_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGC5989424.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="ACIZD4_000465"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="ACIZD4_000465"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGC5989425.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="ACIZD4_000466"
     CDS             21888..22202
                     /locus_tag="ACIZD4_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGC5989426.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="ACIZD4_000467"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="ACIZD4_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGC5989427.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /gene="tmk"
                     /locus_tag="ACIZD4_000468"
     CDS             22887..23531
                     /gene="tmk"
                     /locus_tag="ACIZD4_000468"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGC5989428.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="ACIZD4_000469"
     CDS             23546..23875
                     /locus_tag="ACIZD4_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HGC5989429.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="ACIZD4_000470"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="ACIZD4_000470"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGC5989430.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="ACIZD4_000471"
     CDS             24863..25687
                     /locus_tag="ACIZD4_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HGC5989431.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="ACIZD4_000472"
     CDS             25680..26027
                     /locus_tag="ACIZD4_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGC5989432.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="ACIZD4_000473"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="ACIZD4_000473"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGC5989433.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="ACIZD4_000474"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="ACIZD4_000474"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGC5989434.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACIZD4_000475"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACIZD4_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGC5989435.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACIZD4_000476"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACIZD4_000476"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGC5989436.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="ACIZD4_000477"
     CDS             31684..32451
                     /locus_tag="ACIZD4_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989437.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="ACIZD4_000478"
     CDS             32441..34483
                     /locus_tag="ACIZD4_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989438.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="ACIZD4_000479"
     CDS             34764..34913
                     /locus_tag="ACIZD4_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGC5989439.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="ACIZD4_000480"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="ACIZD4_000480"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGC5989440.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="ACIZD4_000481"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="ACIZD4_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGC5989441.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="ACIZD4_000482"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="ACIZD4_000482"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGC5989442.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="ACIZD4_000483"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="ACIZD4_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGC5989443.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="ACIZD4_000484"
     CDS             39330..40412
                     /locus_tag="ACIZD4_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGC5989444.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="ACIZD4_000485"
     CDS             40412..41215
                     /locus_tag="ACIZD4_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGC5989445.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="ACIZD4_000486"
     CDS             41285..42025
                     /locus_tag="ACIZD4_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC5989446.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="ACIZD4_000487"
     CDS             42036..43040
                     /locus_tag="ACIZD4_000487"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGC5989447.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="ACIZD4_000488"
                     /pseudo
     CDS             complement(43085..44929)
                     /locus_tag="ACIZD4_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            45140..45658
                     /locus_tag="ACIZD4_000489"
     CDS             45140..45658
                     /locus_tag="ACIZD4_000489"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGC5989448.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45786..46469
                     /locus_tag="ACIZD4_000490"
     CDS             45786..46469
                     /locus_tag="ACIZD4_000490"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGC5989449.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46778..46851
                     /locus_tag="ACIZD4_000491"
     tRNA            46778..46851
                     /locus_tag="ACIZD4_000491"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46812..46814,aa:Arg,seq:tct)
     gene            47010..47369
                     /locus_tag="ACIZD4_000492"
     CDS             47010..47369
                     /locus_tag="ACIZD4_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGC5989450.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47492..49123
                     /locus_tag="ACIZD4_000493"
     CDS             47492..49123
                     /locus_tag="ACIZD4_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HGC5989451.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49185..49826)
                     /locus_tag="ACIZD4_000494"
     CDS             complement(49185..49826)
                     /locus_tag="ACIZD4_000494"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGC5989452.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50012..50088
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50108..50416
                     /gene="rplU"
                     /locus_tag="ACIZD4_000495"
     CDS             50108..50416
                     /gene="rplU"
                     /locus_tag="ACIZD4_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGC5989453.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50443..50787
                     /locus_tag="ACIZD4_000496"
     CDS             50443..50787
                     /locus_tag="ACIZD4_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGC5989454.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50800..51093
                     /gene="rpmA"
                     /locus_tag="ACIZD4_000497"
     CDS             50800..51093
                     /gene="rpmA"
                     /locus_tag="ACIZD4_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGC5989455.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51527..54334
                     /locus_tag="ACIZD4_000498"
     CDS             51527..54334
                     /locus_tag="ACIZD4_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC5989456.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            54525..55016
                     /locus_tag="ACIZD4_000499"
     CDS             54525..55016
                     /locus_tag="ACIZD4_000499"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HGC5989457.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55119..56108
                     /locus_tag="ACIZD4_000500"
     CDS             55119..56108
                     /locus_tag="ACIZD4_000500"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HGC5989458.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56141..56944
                     /locus_tag="ACIZD4_000501"
     CDS             56141..56944
                     /locus_tag="ACIZD4_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGC5989459.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56965..57879
                     /locus_tag="ACIZD4_000502"
     CDS             56965..57879
                     /locus_tag="ACIZD4_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC5989460.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            57962..58336
                     /locus_tag="ACIZD4_000503"
     CDS             57962..58336
                     /locus_tag="ACIZD4_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGC5989461.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58475..58720
                     /locus_tag="ACIZD4_000504"
     CDS             58475..58720
                     /locus_tag="ACIZD4_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC5989462.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            58892..59956
                     /locus_tag="ACIZD4_000505"
     CDS             58892..59956
                     /locus_tag="ACIZD4_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGC5989463.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60202..60627
                     /locus_tag="ACIZD4_000506"
     CDS             60202..60627
                     /locus_tag="ACIZD4_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC5989464.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60620..61069
                     /gene="nusB"
                     /locus_tag="ACIZD4_000507"
     CDS             60620..61069
                     /gene="nusB"
                     /locus_tag="ACIZD4_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGC5989465.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61166..62020
                     /locus_tag="ACIZD4_000508"
     CDS             61166..62020
                     /locus_tag="ACIZD4_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGC5989466.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62021..63358
                     /gene="xseA"
                     /locus_tag="ACIZD4_000509"
     CDS             62021..63358
                     /gene="xseA"
                     /locus_tag="ACIZD4_000509"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGC5989467.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63363..63587
                     /locus_tag="ACIZD4_000510"
     CDS             63363..63587
                     /locus_tag="ACIZD4_000510"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGC5989468.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63589..64479
                     /locus_tag="ACIZD4_000511"
     CDS             63589..64479
                     /locus_tag="ACIZD4_000511"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGC5989469.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64488..65306
                     /locus_tag="ACIZD4_000512"
     CDS             64488..65306
                     /locus_tag="ACIZD4_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGC5989470.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65413..65862
                     /locus_tag="ACIZD4_000513"
     CDS             65413..65862
                     /locus_tag="ACIZD4_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGC5989471.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            65880..67562
                     /gene="recN"
                     /locus_tag="ACIZD4_000514"
     CDS             65880..67562
                     /gene="recN"
                     /locus_tag="ACIZD4_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGC5989472.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67617..67733)
                     /locus_tag="ACIZD4_000515"
     CDS             complement(67617..67733)
                     /locus_tag="ACIZD4_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGC5989473.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67806..68762)
                     /locus_tag="ACIZD4_000516"
     CDS             complement(67806..68762)
                     /locus_tag="ACIZD4_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGC5989474.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            68933..69301
                     /locus_tag="ACIZD4_000517"
     CDS             68933..69301
                     /locus_tag="ACIZD4_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGC5989475.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
BASE COUNT        22370 a        11853 c        14668 g        20444 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctagtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaatttat cgttattata tgattaagaa ggattgaata
    45121 aagaaagaag ttgaaaacga tacctgatta caaaaaaata acttttataa gttctataac
    45181 gttgattata tttttaattc ttattcttct cgtcgtcttg gttccccgaa tttttggttt
    45241 gactccttat attattgagg acaaagaaat gagtccatat tatgcacaag gaaatctgat
    45301 atatgtacga ccgaaaaata caaatgagat tttagtcgga gatattatta catattatga
    45361 aaattcagga aaaaaaatct cgacgcgtcg cgtaatagcc gttgaaaaca accacgaaga
    45421 tttttataca aaagctgata caaagactta tattgagcct ggagtagtaa aaaagagaaa
    45481 tattatcggt agtcccatct ttcagattcc atatattgga ctagtccttt caaaaacggc
    45541 atttgcatgg attcaggggt tattctttac gattgctttt tgcctaacag gaatcacagc
    45601 atggaatacc tttgtagagt tgaaaaagaa gcggagacga acacagaaat ttttgtaaga
    45661 atgttaaaaa cataaatgta ttccagagat ccaacgactc ttctgaacat gaaacacgag
    45721 aaaacactca tgcagcttgt agatttagtc agttgttcgt ataatgtgtg aagaggagga
    45781 gtagtatgcg caatgaaatg atgcatcgtc ctgtagtcaa agaagaacta ttggatttta
    45841 tgcgtaccca gcaaaaaaaa ttaccgggtg agctaggcaa actggaagaa gaagctcatg
    45901 tagcagaagt accagttatt ccccatgaaa cagttgtatt tttgaaattt ttacttggac
    45961 agcttcagcc tgaacgaatc ttggagatcg gagcagctat cggtttttca tcaagtgtca
    46021 tggccacgac aatcggagaa aacgctcatg ttacgacaat tgatcgtttc gatgtcatga
    46081 tcgagaaagc taaaaaaaac tatgaacgtc taggactgac agataaagtg actttgcttg
    46141 aaggtcaagc agcagatatc ttgccggagt tgtctggtcc gtatgacttt atttttatgg
    46201 atagtgcaaa atcaaaatat attgaatttt tacctgaatg cttacgtttg ttaagaaaag
    46261 gtggcgtttt gatggtagat gacatcttcc aaggaggaac gatcttgctc ccagatgaag
    46321 agattccccg tggcaaacga gctatccatc gtaaattaaa tgaatttctt cgtgttgtga
    46381 tggatcatcc cgatttgaca tcgacaatct tgccattagg tgatggtgtg atcttaatga
    46441 caaaggaatc agaaacaatc gagttgtgat acatgattat ggcagcctgt agataatcga
    46501 ttgaatcgag ggctcaattc gaacttgatg taaaagtttc tatatttgta agtcaattaa
    46561 aggatacagg aaatctaaat aaacaggagt agcatgaagt caatgtagct cctgttttca
    46621 attgataacc ttagaacagc tgaaggagaa tgtctcgttt taaaagattg atttagtagt
    46681 tgggccaaaa taattcatta tttgctaatt aaataactat ttcgtattga cagaagcaat
    46741 ttaattatct ataattattg atgttccgct gattcttgtc atagtagctc agctggatag
    46801 agcatccgcc ttctaagcgg acggtcgggg gttcgaatcc ctcctgtgac gctaaaaaac
    46861 cgttagaaac tgaggtttct aacggttttt ctttgttttt tgtgccaata ttgtttgttt
    46921 tcaaaggcaa ataaaataaa aaaacatcct tatcgagtac aattataagg agcaaaaaaa
    46981 taaaactcat cagaaaagag gaagaagata tgacgatact atctagaatt ttagtgactc
    47041 tagttgcaat tgaatttttt tatatcatgt atatcgaaac ggtgagaact gattctgaca
    47101 cgacaagtag ggtttttaaa atgagtaaag aagagttaag cagaaaatct gttcaaacat
    47161 tgtttaagaa ccaaggagtg tacaatggac tattaggagt gggactactt tatggagctt
    47221 atctttcttc cgcatctaaa gaaatcacaa gtatgctatt aatatctatt ttttttgttg
    47281 cattatatgg cagtttgact agcgatcgtt ggattttact caaacaaggt gggctagctc
    47341 tgttggcatt gctttctatt ttcttataaa tatagaaaaa ataagaattt atctaacagg
    47401 aaactttgtg aaaaatatta ctttatctca tgaaatatga tattctaatg aatggtattt
    47461 tagaaaattt catgaaaaag gagttagata ggtgttcaaa aattatgttt cctcactaaa
    47521 aaaagaattt tcaggttatg atctttcaag atttcagaaa gatcttttgg ctgggatcac
    47581 agtagctgct gtagcattgc ctttagcctt ggcttttggg gtatcaagcg gagctgatgc
    47641 ggccgcaggt ttgattacgg ctatcattgc cggtatcgtt attggcggtt tatcaggcgg
    47701 tttttatcaa atatcaggtc cgacaggtgc gatggcagct atcttgatgt ctattgcggc
    47761 aacaaaggga atgcaaggtg tattgcttgc tactttttta gcgggtctat ttttacttgc
    47821 agcaggactt ttccgattag gaacactgac ttcttttatc ccagcacccg taattacggg
    47881 gtttacttca ggtattgcta tcattattgc attaggtcag atcgataatt tatttggtgt
    47941 tcactcggaa ggtacaaacg ttattgaaaa actaagtagt tatcaaacga taggatttcc
    48001 gataaacaca gcctctttga tcatgggagg gctagtcatt ttagggatgt ttatctatcc
    48061 aaaaaaatgg gcgaaacgaa tgcctagttc gctgctggct atcattttgg caacagcagt
    48121 tatgctattg ttccatttac cagtagcaac tgtgggtaag attccacaaa cattgatcag
    48181 tagtaatcgt ttgaatatgg gagattttag cttttctgcc ttgcaacaag tggcagttcc
    48241 agctattagc attgctttat taggaatgat tgaaagcttg ctatgtggtg cttcggctgg
    48301 ccgaatggca aataagccct tagatagcaa tcaagaatta atggcgcaag gaattggaaa
    48361 tctgttgctt cctttctttg gcgggattcc tgctactgcg gccatcgccc gtacaagcgt
    48421 ggccatcaaa tctggtgcac aaactagatt agctggtatg atacatgcag ttgtcttact
    48481 gctctccatg cttgtttttg cgccagtgat gtcacagatt ccaatgccag cacttgcagg
    48541 tgttttgatt gtgacggctt ggcgtatgaa tgaatgggaa acgatcaagg agctatttac
    48601 taataaatat tggtcagcag ttctattgtt tatccttacg atgatttgta cagttatctt
    48661 tgatttaagt attgctatcg tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa
    48721 aagcgctgct atcacgattt cattagaaac gatcgattgg caaagaatgg ggctgccaga
    48781 aacggaaaag ctgaataact ggacagtagt gtatattagt ggtccactgt tttttatgtc
    48841 ttcagaaaaa ctcaaaaata aattggaaga actaaatcat cacgatggtg tcattttctc
    48901 catgcgaggc gtaccaagta ttgatttgac ggcacgtgca gtttttgatg aatttcaaga
    48961 aaaagcagag caaagaggac aaacgattat ctatacttcc ttgcagccag aagtagaaaa
    49021 acaactttct cacttgtggg aacatacatt cacgcatcaa catcaaacag ttgctcatgc
    49081 gttgacagct ttacatgcga aatatactgc aattagccat taaaacaatg aaaaagaaca
    49141 gacaagactg taaactgaag attttatggt cttgtctgtt ctttttaata ttgctgtaaa
    49201 agtgaagcta gtacttgcca gtcttgatgg ataacaggta caagggagcg attgtagaaa
    49261 atagctgctg gatgaaaaag tggaagaatt cgatagtttt tttctgacca ttcgtaggca
    49321 tccttttgtt ctgttaattg taagacaggc cctgtataga gttgaccatg atttttggta
    49381 accgtatatt ctttgccaag taaacgttga agaccaatgt ttccaagtgt cgcaattaat
    49441 tttggctgga ccttcatcag ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa
    49501 cgagtaggtg tccgatttgg ataaacagtt tctgactgtt gtgtccgttt attgatccga
    49561 tgagtcacgc gatacgggcg gctccttaca gcactggtga tatacacctc ttctcgtgtt
    49621 aagccagttg aagaaagtgc ctgcatcaat tcttttccag cttgaccgct aaaaggaaca
    49681 tgcgtatcaa tctctgtttt ccctggggct tctcccacga gcatcagttt aggatgaaga
    49741 ggtccttgcc cagcgataaa tccttctaca ggacggccgt tcattcttaa agaagcttct
    49801 tgtatcagtt cttttgggta ttccatttat gctcctcctt tttcttttat tataagaata
    49861 aaagaaacac aatgcgacta ttttatttgg tagaactgtg aggatagaaa agcagaagta
    49921 ttgcttgaat ttttgtttta ctttttgatt ttaaatttag ttgactaacg gttgctgttc
    49981 tggtaagcta gtactgttgt aattgtggac tccacagcta caaccgctca gaacaagtaa
    50041 taagcacagc atatgctgtc acttcggatg gcgagtctaa gtatatcaga aggaggtgct
    50101 ttatagcatg tacgcaatta ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca
    50161 agcaatctat gttgaaaaac ttgacgttga agcaggagaa aaagttgttt ttgacgaagt
    50221 tatcttagta ggcggagaat ctacaaaagt aggcgctcca actgttgcag gtgcaactgt
    50281 tgaaggtact gttgaaaaac acggcaaaca aaagaaagtc gttactttca aatacaaacc
    50341 taaaaaacat tcacaccgta aacaaggtca tcgtcaacca tatacaaaag tggttatcga
    50401 cgcgatcaac gcttaatagc gtttgagaaa gaaggcctat atatgatcaa aggaacattt
    50461 aagcgaaatg acgcaggtca gatcgtttca ttcactttga ccgggcatgc tgatgctggt
    50521 ccttatggaa gtgatatcgt ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac
    50581 gggattgcct cattagccgg ttttgagccg attgttgaaa tgaatgaaga agaaggcggt
    50641 tatctttata ccgaagtcac ttcaggaatg acacaagaac aaaacaatat tgctgagatt
    50701 ctattagaaa atcttttatt aggattacaa tcgatagaag ctgaaaactc agaatatatc
    50761 caaattaaaa caattaatga taaataggag gtgcagacca tgttgttatc tatgaatcta
    50821 caattatttg cccacaaaaa aggtggcggt tctacatcta acggccgtga ctcagaatca
    50881 aaacgtctag gtgctaaacg tgctgatgga caaacagtta caggtggatc aattctttac
    50941 cgtcaacgcg gtacaaaaat ctatccaggt gtaaacgtgg gtatcggtgg agacgacact
    51001 ttatttgcaa aagttgatgg cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa
    51061 gtgtctgttt atccagtagc tcaagaagct taattgaatc ttatgattaa agaggttgtg
    51121 acaagacttt tgtcacagcc ttttttgttt ataaaaataa aagttgtagt ggaggctacg
    51181 aagtttactt tgtcttttta cacttaatat ttttttgcca atttggaatc aggatgtttt
    51241 gataactatc gttttcaatt gatggaagct atattgtttg ctatcagtga aataattata
    51301 tggtaaacag tgttcttttt cttgtttcca ttataaaaat cgtatcggga tttttcgttc
    51361 ttttaaattg aacatttcta tctatccgcg tgttatcaac aaaacaaaat caggtaaata
    51421 gttgacgaaa cagaaataaa tacatagtat tatgttttga agcctaagta caatagtcta
    51481 tagaaaagga gcgataccat tggcaaaacg cattgaccga atttatatgt atgtcaaaga
    51541 aaaaaccgct catttaacaa aggcagaata tgatcaagga gtaacaacac aggaaattgc
    51601 tgaagtgtta gggattcagc gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga
    51661 aggaaaactg ataaagacag acggacgacc agtacgttac atatatcaaa cactcgttac
    51721 gcacgtaaag ccagttacaa aacatgtagt cagttacaaa gaaacgccgg tctctgaaga
    51781 aaaaaataca ctccaaatag atactaagga tatctttgca aaaatcattg gagctaacgg
    51841 cagcatgaaa aattcagtgg aacaggcaaa agctgcgatt ttgtatccgc caagaggatt
    51901 aaattgtttg attacaggac ctaccggatc aggaaagact tattttgcac acgcgatgta
    51961 tcattttgca aaagcgcatc atgtaataga tgaggaaacg gaactgattg ttttcaattg
    52021 tgctgattat gccaataacc ctgagctttt gatgagtcat ttatttgggt acgcaaaagg
    52081 tgcttttaca ggcgcagatg aagaaaaaat ggggattatc gatcaagcgg atggcggtat
    52141 gctgtttttg gatgagattc accggttgcc gcctgaaggt caagaaatga tcttttactt
    52201 tatggatcat ggaacttaca gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt
    52261 acggatcgta ggtgcgacca cagaagaccc aggttcttct ctattagaaa cttttgttcg
    52321 gcgtatccca atcaatatca aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt
    52381 cgatttagta aaaatcatga ttgcccacga agcaaaccgc acgcagcgaa agatttcttt
    52441 gacagaagat gtagcaaaag cattgatcgg cagtgtgacc tatggaaata taggacaatt
    52501 gaagtcaaat atccagttag tatgtgcacg aggatttcta aatcatatgc aatcacccga
    52561 aatctcgatc acaatcgatg atttgacaga agggattcgt agcggattga ttcaattagc
    52621 aagcaaccgc agtgcaatgg cagagctttc taaaatattg gagccaaaga taactgtagc
    52681 accaaatgat acgatcatga aaatccaatc ggactcctat gagttacctt ataatctata
    52741 tgatatcatc ggagataaag cagctttact gaagtcggat ggtttggatc aagaagcaat
    52801 caatcatttc atttctacag atatcaacat ccatctgaag tctttctata aagaccatgg
    52861 tttttctttt aatgcagaca gcaaattagc agaatttgta gatccgaaaa tcatagaagt
    52921 gaccaatcag atttatgtaa tggtcaaaag atctttacca tatgagtttc agcaaaactt
    52981 tatttatgct atgagcttgc atatcagttc ttttttgaaa aaaatcaact taggagaaga
    53041 acggcatacg aatgataaca tccgtgagat ggcttttgat tttccagatg aatatgctgt
    53101 tgcgaaagaa gtgcgtagtt atatcgaaac gtattttcaa gtggagattc cagaaagtga
    53161 agactattac ttgaccgttc tactcgtctc gttacgggca aatcaagcaa gcggcagaat
    53221 cggtgtagtc gttgcagctc acggaaacag cacagcaagc agtatggtcc aagttgtcca
    53281 acagttgtta gatgcagaga acgtacgagc agtagacatg cctttggata tggatccgaa
    53341 aacagcattg gaccgaattg aacgcaatgt acaagaagta gatgaaggaa gcggggtcat
    53401 actcttagta gatatggggt cccttgcgtc gtttaattcg caaattcaaa gagacactgg
    53461 aattccagta cgtactgttg atatggtaac aacttctcta gttttggaaa ctgtacgaaa
    53521 ggtctcagta ttagggacag atctagatat gttgcatgaa tcattgaaaa attttcgagg
    53581 ttacgcagaa atatcttctg tagaatctgt tcaggaagca aaacctattc ataagaaaaa
    53641 agctgttttg gctatctgcg catctggcga aggtacagca caaagaatca aagaattgat
    53701 cgaacgagcg gtaaacaagc gtcaagaaac agaattagaa gttctagctt tgtcgattgt
    53761 ggaagtgaaa gaagaactgc cagttatcca aaaagaatat cagatcatag ctactactgg
    53821 gattactgat ttgaatatcc aagccccatt tattccttta gaacgtttta ttgatcaaaa
    53881 tatcgaagtc attttggatc agttgctgat ggaatcagaa ttggaggaaa ctgaattcat
    53941 ctccctagat gaagagtcag ctaaaaatac gtgtgttgag tttatctctg ataacttcat
    54001 ctttattaat ggtagtaagt taatcgatcc aatgtggcaa ttttctacac aaatctctca
    54061 gacgacggga atcggcgatg aagaatatgg attcaaaatc aacctagtga tgcacacagc
    54121 aggaatgatc gaacgtatta ttcggaatga accattgact gtggaagaaa acgaattgac
    54181 aaatacaacg aatgatcctc tttatagcca attggcagcc tcagttgttc tgttggaaga
    54241 tcagataaaa gtaaaagtgc cgatagaaga aatgtattat ctgctacgtc tagtccataa
    54301 tcagttagat aaaaaagaat acactgtgcc atgaatacac aaaaacgata cacttttata
    54361 gtgtatcgtt tttgtgtatt ggttaagaat cctttaaatt caattagtgt atcgtaaaaa
    54421 agttggcacg ctttttgctt atagtagtgt gtgctaggag gtggttgttc acacagaaat
    54481 gataggggtt tctgtgaagt agtgaggaag aaggagtttt gcagatggat attcgattgg
    54541 cacgtataga tgatcgttta atccacgggc aagtcgcaac agtttggtcg aagcaaacag
    54601 gtgttgaacg tatcattgtg atcagcgatg tagtcgctca agataaattg agaaagtttc
    54661 tactaaaaga agctgcaccg ccggggatca cagcaaatgt aataaccgtg cagaaaatga
    54721 ttcaaatcta tcatagtgga ttattatcac gagcaaaagt gatgctttta ttcaccaatc
    54781 cccaagatgt tgaagcggtt gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg
    54841 gtatgagttt tactgaaggc aaatcaatga ttaccaattt tgtttcagta aatcaacaag
    54901 atattgattc ctttcgttac ttgaacagtc aagaagtgga gttagagatt cgaaaagtac
    54961 ctgctgacag gaaaatcctt ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag
    55021 aatggttgtt ggaaaaggtc aaataattct gttgtaatgg ttagcaatta ttaatatttt
    55081 tgaatttgtt acaacaaaag taaataggag gtataaatat ggtagggatt atcctagcaa
    55141 gtcatggaca atttgctgaa ggaatcttac aatccggttc aatgatcttt ggcgaacaag
    55201 aaaacgtcaa agccgtgatt ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat
    55261 tggaagaagc ggttgcttct tttgataatc aagacgaagt gttattctta gttgatttat
    55321 ggggcggaac accgttcaat caatcaaaca cattattcga agagcacaaa gataaatggg
    55381 caatcgtcag cggtttgaat ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa
    55441 tggaatctgc tcatgaaatt gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag
    55501 taaaaccgga agaattagaa ccggcagaag caccgaaagc agcagttgaa gacgcacaac
    55561 ctaaaggagc acttccagaa ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag
    55621 cacgtgttga ctcacgtctg ttacatggac aagttgcgac agcttggaca aaagcagtgc
    55681 aaccaaaccg tattatcgtt gtttcagatg cagtatcaaa ggatgatctg cgtaagagac
    55741 taatcgaaca agctgctcct ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga
    55801 tcgaagtagc aaaagaccct cgttttggaa ataccaaagc attgctttta tttgaaaatc
    55861 ctgaagacgt attgacagct gttgaaggtg gcgtagacat caaagaatta aatgttgggt
    55921 caatggcgca ttcggtcggt aaagtcgttg taagtaaagt attgtctatg ggacaagaag
    55981 acgttgaagc gtttgagaag cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac
    56041 ctaatgattc acgcgataac atggatgata ttttgaaaaa agcaaaagct gaattagcaa
    56101 aagcgtaata aataatatta aaatttatag gaggcttatc atgtctatta tttcaataat
    56161 tttagtcgta ttagttgcct ttctagctgg tatggaaggt attcttgatg aatttcaatt
    56221 tcatcaacca ctagtggcat gtacattgat cggtttagtt accggtaacc tcgaagctgg
    56281 tatcgtactt ggcggtacgc ttcagatgat cgctttaggt tgggcaaata tcggtgccgc
    56341 tgtagcacca gatgctgcat tagcatcagt agcatcagca attattttag ttttaggtgg
    56401 acaaggtgtt aaaggtgttc cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg
    56461 gttgttctta acaatgatcg tacgtacaat cgctgttcca atcgttcatt tgatggatgc
    56521 ggctgctgaa gaaggaaaca tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt
    56581 acaaggggtt cgtatcgcgg tcccagcagc agcgttgcta tttatcccag cacaaactgt
    56641 gcaatcattc cttgaatcaa tgccagcatg gttaacagat ggtatggcta tcggtggggg
    56701 aatggtcgta gctgtaggtt acgctttggt aatcaacatg atggctacaa aagaagtatg
    56761 gccattcttc gttattggtt tcgttgtagc tgcaatttct caattaacat tgattgctct
    56821 aggtgcttta ggtgttgcat tagctcttat ttacttgaac ctttctaaaa tgggtggttc
    56881 atcaaataat ggaggcggaa gcaactctgg tgacccttta ggcgacattt tgaatgacta
    56941 ttaatcttga aggaggaaaa taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat
    57001 cgtttagctg ttgcgtggcg ctctaccttc attcaaggtt catggaacta cgaacgtatg
    57061 caaaacggtg gctgggcatt ttctatgatt ccagcaatca aaaaattata caaaacaaaa
    57121 gaagaacgtt ctgcagcatt aaaacgtcac ttggaattct ttaatacaca cccatacatt
    57181 gcttctccaa ttttaggggt tacattggct ctggaagaag aacgtgcgaa tggcgcgcct
    57241 gttgatgatg tagcgattca aggggttaaa gtaggtatga tgggtccttt agctggtgtt
    57301 ggtgacccag tgttctggtt tacagtacgt ccaatgctag gtgcactagg tgcttcatta
    57361 gctatgggag gaaatatcct tggaccaatc atcttcttct taggttggaa cattattcgt
    57421 tgggcattca tgtggtatac acaagaattt ggctacaaag ctggttctaa aattactgat
    57481 gacctttctg gcggattgtt acaagacgta acaaaaggtg cttcaatttt agggatgttc
    57541 gtattagctg cccttgtaca aagatgggta tcaatcaaat tcttaccagt tgtatcaact
    57601 gtaaaattag ataaaggtgc ttacatcgaa tgggataaat tgccttcagg tggtgaagga
    57661 atcaagagtg catttgaaca agttaataat ggcttagccc tttctcctga aaaggtaaca
    57721 acattacaag acaacttaga ccaattgatt cctggtttag ctgcattagg attaacattg
    57781 ttatgtatgt ggttgcttaa gaaaaaggtt tctccaatcg ttatcatcct tggtttattc
    57841 gtagtcggtg ttgttggaca cgtcatcgga cttttataat ccataaaaat atagctcggg
    57901 cgttgtcccg agcttttttt atatagtata ctgttcataa acaaatatct ggagggagaa
    57961 aatggttcaa tcaatcaata caaaagtaga cttggtaatt gatgctactt cgtttacggg
    58021 tctgacagat tacgggcaaa tcatgatagg taataatggt tttgagtttt accatgcgcg
    58081 agatagacgc aaatatatcc aaattccatg ggaagaagtg gattatgtac tagcatcagt
    58141 catgctaaag ggaaaatgga ttcctcgata tgccattcaa acgaaaaaaa atggtacata
    58201 cacattttct tccaaagaac ctaaaaaagt gcttcgtgcg atcagagaat atgtagatga
    58261 agatagaatg gtacaatcat tgagtttctt tgatgtagtg aaacgtggta ttcgtagtat
    58321 gtttaaacgc aagtaaaaaa taaagaaaac ttctaagagg aggttttctt tattttttta
    58381 ctttgcagaa gaaaatatga aatagcaaaa ccaattattt gtccccttta aatcccatat
    58441 gctaaaattg attagcaaag aaggaggtta tattatgagt tggttatgga cattgattgt
    58501 tggagccgtg atcggagcaa ttgcaggtgc gatcaccagt aaaggaaatt cgatgggctg
    58561 tgtaacgaat atcattgctg gactagtcgg ttcaagtatt ggacaagcga ttttcggcga
    58621 atggggacca aaagctgcag gtatggcact tattccatct attttaggcg cagtgatttt
    58681 ggtagcagtt gtctcatttt tctttggaaa acgatcataa gtttttacaa aatagtaaac
    58741 taaaaggagt tgcagcgaga ctgtgactcc tttttggctt tatttattta aaataaaaag
    58801 aagttttccg gaaattttta tttaactgtc gtgtacgaag aaaagtttgc tataatggaa
    58861 aaaagcgtgc aaagaaagag ggagtttcat tatgatgcta cgtgtagaaa aattgcgcaa
    58921 aaaaatgcaa gaagaaaatt tggattcatt tttggttacc agtccgtaca atcttcgtta
    58981 cttaacgaac tttacaggta cgacaggatt agctgttatt actttggaaa aagcattttt
    59041 tattactgat tttcgttata ccgagcaggc ggcagcgcag gctcaagggt ttgaaattat
    59101 taaaaatgtc ggacctattt ttgatgaggt agcaaactta gtacgcaaag aagaactgca
    59161 ctcattagct tttgaggaaa caacagtctc atttttagaa tattcggttt tagaagaaat
    59221 catcgatgcg gaattagtac ctgtttcaca gatgatcgaa gaactcagag aagtgaaaga
    59281 tgaagaagaa atcgctatta tcgaaaaagc atgtcatatt gcggatatgg catatgatca
    59341 catcctgaaa atgatccaac cgggcatgac tgagattgaa gtcgcaaatc aactagactt
    59401 ttatatgcgt tctcttggcg cttcaggtgt ttcttttgat acgatcgttg ctagcggatt
    59461 gcgttcggct atgccgcatg gtgtagcaag caaaaaaatc atcgaacaag gtgacttgat
    59521 cacattggac tttggttgct attacgaagg gtacgtttcc gatatgacac gtacattcgc
    59581 tattggtgat cctggggaaa aattaaaaga aatttatcaa atagtcttag atgctcaatt
    59641 agcagttatt gatgctgcaa aaccaggaat gactggtgtc caattagatg cagttgctag
    59701 agattatatt tcaaaacatg gttacgggga agcatttgga cattctacag gacatgggat
    59761 cggtttagag atccacgaag gaccaaacgt ttcttctcgt gcagaaaagc aatttgtacc
    59821 aggaaatgtg atcactgatg aaccagggat ctacttacca ggaatcggtg gagtacgtat
    59881 tgaggatgac ttgttgatca cagaagatgg aaatcgtgtg ttgactcgtt caccaaaaga
    59941 attgatcatc ttatagtttc atcaatagaa gaagtaagcg taaaaatcag tgttcacaga
    60001 ctttgttata gaaaatcact cgatttaatg atacactata gaagaacttt taagctgtaa
    60061 gagataataa agttgggtgt tttctccaat tcatagcagt ttgcagctga tcggcggcag
    60121 ttttcttacc acgtgatcac tatgccgcat catagagaat tcggatgtat ctcgtgctta
    60181 ggcaaaggga ggaataaata aatggcagat gaaaaaaatt tgattttaaa cgcaaaccaa
    60241 gatttaggag agatcgtgat cgctcctgaa gtcatcgaag taattatcgg gattgcagct
    60301 tctaaagtag aaggcgtata cggaatgcgc ggaacttttg ccagcaatgt cactgaatta
    60361 ttaggacgtg cagctcacgg aaaaggtgtt tacttagcaa acgaggaaga tggcttgaaa
    60421 gtagatcttt actgttatct agaatatggt gtttcagttc ctaaagtagc aatggaaatg
    60481 caggaacggg tcagccagca agtccttttc atgacggata tcgatttatc tgaagtcaat
    60541 atccatgtag tagctgttgt tcctgaaaaa ttagaacaac caacaatcga agaacttttt
    60601 gaagacgaag aggaagagaa tgaataaaga attatcaaga cacgagattc gggaaatggc
    60661 attgcaggct ttatttccat tagacttcaa tgcagaccta acaaaagaag atgcgatttt
    60721 caacgcaatc gaattagacc accgcgacat gatcaacgaa gatgaatcag agtttgttcc
    60781 tgtttatctt gatacgctag ttggcggtgt ctgtgcaaaa aaagatgaat tggataaagt
    60841 gattgaaaaa catttaaaaa acaattggca catcaatcgg atctcaaaaa tggatttggt
    60901 gatcttgcgt atcgcgattt ttgaaatgac ttatgtgaca gatgtaccag cggctgttgc
    60961 tttaaatgaa gcaatcgagt tggcaaaaac atttagtgat gaccgttcac gtaaattcgt
    61021 caacggtgtt ttatccaatg tattgaaaga attagaagct ggggcgtaag tcctagcttt
    61081 tttctatgaa tcatcataaa cctgttataa atcgggaaaa ttctatggta gaatgaaaac
    61141 acaaaaaata tctgggagtg gttagatggc agaattgatt aacggaaaag aattagctga
    61201 aaaaatgcag gcagagattg ctgaaaaaat ccaaaaattg aaagataatg gtatccatcc
    61261 cggattagtc gttttattgg taggggaaaa tccagccagc caaatctatg taagaaataa
    61321 agaacgtgta gcaaaagaaa tcggaatcca ttcattggta gagcgttatc ctgagacgat
    61381 ttctgaagac gaactacttg cagaaattga aaaatacaat caagatccta gttttcatgg
    61441 tatattggtc caattaccat tgccaaagca tatagatgaa gaaaagatcc tgttagctat
    61501 ccgccctgaa aaagacgtag acggttttca tccgatgaat ttaggcagac tccttgcggg
    61561 taaaccggac aagattcctt gtactccata cggcatcatg aaaatgtttg aagcttattc
    61621 tatcgatccg gcgggtaaac gagcagtagt tatcggacga agcaatatcg tcggtaaacc
    61681 gatggctcag ctactcttga tggcagatgc aactgttact gttgctcatt ctaaaaccga
    61741 aaatctggct gaactggcac aagaagcaga tattttagtc gtagcaatag gacgtggaca
    61801 ttttgtcaca aaagaattcg taaaaccagg tgctgtagtg atagatgtag ggatgaatcg
    61861 tgatgctaac ggtaagctga tcggtgatgt gaaatttgat gaagtggagc ctattgcagg
    61921 ctggatcact cctgtgccaa agggtgtagg gccaatgact atcacgatgc tgatgtatca
    61981 aaccgtaaaa tctgccgaag cttttggagc aggtgaatag atggcacaag aatatttaac
    62041 tgtcactaca ttaacgaagt atttgaaaag aaaatttgat gccgatcctt atttagaacg
    62101 cgtatattta acaggcgaaa tatcgaattt ccgtttacgt gccaatgccc atcaatattt
    62161 cagcttaaaa gatgaccatg caaaaatatc tgctattatg ttcaaaggag cattccaaaa
    62221 attacgattc cagccaaaag aaggaatgaa agtccttgtc gttgggcgta tttcattata
    62281 tgaagcggga ggttcttatc aaatctatgt agagcacatg gagcctgatg gaataggtgc
    62341 tttatatcaa gaattggaag aacgaaaaga aaagctgatg aaggaaggcc tttttcaagg
    62401 gcctaaaaaa atgctgccac gtttcccaaa gcgaatcgcg gtccttacca gtccaagcgg
    62461 agcggttatc cgcgatatca tcacgacggt gaaaagaaga tatccaattg tccaattggt
    62521 tttgttccca acagttgtac aaggaaacca agcagcggac aatgttgtca ggaatatcca
    62581 gagagtagaa gagatgggca atttcgatac aatgatcatc ggtcgtgggg gtggttcgat
    62641 tgaggattta tggccgttta atgaagagcg ggttgctcgg gcgatttatc aagctaatac
    62701 gccggtgatt tcatctgtag gacatgaaac agataccacg atcgctgatt tagtagcaga
    62761 tgttcgggct gccactccaa cagcagctgc agaattagct gttcctgttt tgtcagaaga
    62821 gttgatgcgc attcaagaac ggcaagctag attgcagcag gcgtttgtac gccagatcca
    62881 gcgcaaacaa gaacggttcg agcgtgctcg acgttcctat gtatttcggc agcctgaaag
    62941 attgtatgaa ggtcagacca tcaaattaga ccagttgaaa cagcgattat atcaagctac
    63001 acagcaaatt tatcatgcga aagaaaaaca aacgatcgca ttaagccacc aattggaaca
    63061 agtggctccg ctttatcgag ttaaagcagc tcgccaagaa actgcttatc tagaaaaacg
    63121 cttagaagag aaaatccaac aatatatgaa acaacagcag cagcgttttg ctcaagctgt
    63181 tcaatctctt gatttgttga gtccattgaa aatcatggga agaggctaca gctatacgac
    63241 gttaaatgat caagtagtaa aaagtgtcac cgagattcat caaggggatt tgctgacgat
    63301 ccattatcaa gatggaatcg ttaaaggaca agtacaagag atagacaaag gagaataaaa
    63361 atatggaaaa tccaactttt gaagagtcac tgcaagaatt agaaaaaatt gtcatgcagt
    63421 tagaacaagg agacgttcca ttagaatcag ctctagattc gtttaaacga ggaatggaat
    63481 taagcaaaca ttgccaagat acattagcta aagcagaaga gaccttgacg aaaatgatga
    63541 cagaatcaaa tgaagaagtt gattttgacg gaaacgagga aagctgagat gagattaact
    63601 gacttttcag ctattcatct acctgctgta gaaaaagaaa tcttgtcttt tttagatgag
    63661 catacaacgg atagaggact ctatgatgcg atgagttatt cagtgaaagc aggcgggaaa
    63721 agaatacgtc ccttattact tttaacggcc gttgcttcct ttgatgagcc tattgatgtt
    63781 cccgtctatc aagtagcagc tgctttagaa atggtgcata cgtattcctt gatccacgat
    63841 gatttgcctg cgatggacaa tgatgatctt cgtagaggaa aacctaccaa tcataaagta
    63901 ttcggcgaag cattagctat attggccgga gatggtttgc ttacaggagc attccagcta
    63961 atcagtatgg cacacttagg taattctcct aagcttctgc tgcttcagca attagctgtt
    64021 tgtgcgggat cacaaggtat ggttgctggg caagctgcag atatcgaggg cgaatcgaaa
    64081 aagctttctt tagaagaatt agcatttatt catgaaagaa agacagggca tttgattcgt
    64141 tatgccttgc tggctggtgg catattagcg aagcaacctg aagaaatctt attgctactt
    64201 caacgattag ccgaacattt aggtttagct tttcagataa gagatgatct actcgatgtg
    64261 attggtacaa cgaaaacatt agggaaaaca gctggtaaag atgaacgtat ggaaaaaaat
    64321 acttacccgc gtttattagg cctagaaaag acacgtgagg cgttggagat tgagctgtta
    64381 tccgccaaca agatcataga caaattagaa gaggacgttt tttcttttga tggcgggctg
    64441 atgcgccaga tgatcaagca atttgatgtg gagaaatgag ggaaagaatg gaaaaagaac
    64501 gcgtagatgt attagcggtc aaacaaggat tatttgaaac aagagaacaa gccaaacgtt
    64561 cagtgatggc tggtttgatt tacaacgaaa aaaacgagcg gtttgataaa ccgggagaaa
    64621 aaattccagt gagtagtgaa ttaagagtca aaggtaaaaa acttccttat gtttctcgag
    64681 ggggattaaa attagaaaaa gcactcaaag catttgatct atctgttgaa ggaaaaacat
    64741 tgttagatat tggtgcatcc actggcggat ttactgatgc agctttgcaa aatggcgcaa
    64801 aaatgagtta tgctttagac gttggctaca atcagctagc ttggaaaata agacaagatc
    64861 ctagagtcgt cgtaatggaa agagtgaatt ttcgttatgc aaaacccgaa gactttacct
    64921 taggaattcc agaagttgct gttatcgatg tttcttttat ttcactaaaa ctgatgctgc
    64981 ctccattaca tgctatttta aaagaagagg gagaagtgat tgctttaatc aaaccccaat
    65041 tcgaagcagg cagagaagct gtagggaaaa acggaattgt tcgtgaccct cagacccatc
    65101 aaaaagtttt agaagacatt ttgtcatttg cggcacaagg tggatatgat gtgctggaat
    65161 taagttattc tccgatcacg gggggagaag gaaatatcga gttcttggct cacttgagga
    65221 aagtacccga aagcggaaca atcaattcag ctattaatat ggcagaagtg gtttcaaatg
    65281 cacacgaaca gtttgaccat aaataaattg taactgtgaa aatcaagtga gaagtatgcg
    65341 gattcttctt tattatacca aggaaataag ctatcattga ttaagaagaa tatgctaagg
    65401 agcgaagacg taatgagaaa aaaagatcgg catcgtttga ttactcgatt gttgagtgag
    65461 caagatatcc gaaagcagga agaatttgtt gaaatcctga aaagcaaagg aatatctgtt
    65521 actcaagcta cgatttccag agatataaag gaactgaaac tgatcaaggt accggcttca
    65581 gatggcggct accgttatag cataccagct gaaacaaacg aagatgtaaa tactaaattg
    65641 gaaaaactat taaaagacgc tttcgtggca gttgaccaaa tggaaaaatt tgttattttg
    65701 aaaacattgc cgggaaatgc ttcggcagca gcaaatttga ttgataaacg ttacaagaaa
    65761 gaattatttt cgattatcaa tgatgacgat aatgttttga tgattacacg aactgaagac
    65821 caggcagttt tattgaagaa agacttcctg cattaccttt aagttgagga gcgaatgtga
    65881 tgctacaaga aatcagtatt actaactttg cgattattcc ggaattgcgg ctttcttttc
    65941 acgaaggaat gaccgcgctg accggagaga ctggtgcggg taaatccatt attatcgatg
    66001 ctttaggtct gttagcagga ggaagaggtt caagcgatta tatacgtcaa ggagcagaaa
    66061 aatgtgtgct tgaagggttg tttgaactac caaaacaaga aggattctct gaactgatgg
    66121 ttgaattagg gatcgaaaca gatgaggaca atctgattgt tcgacgggat atgtccttaa
    66181 ctggaaaaaa tgtttgtcga gtgaatggtc atattatcac attagctaat ctgagaagaa
    66241 tcggcagtta tttagtagat atccaaggac aaaacgaaca tcaggaactg ctccagcctg
    66301 aatcacatct tgctttattg gatcgttttg gagatgtagc tttccaacag aagaaaaaga
    66361 gttatcagca agaatatatc tcttatcgtg agctggaaaa aagggtacga aaagtgcagc
    66421 aaaatgaaaa atcctatgtt cagagaatag atatgctcca tttccagcaa gaagaaatag
    66481 ctgctgctga tttgcaagtc ggagaagaag agaaattaaa agaagaaaga gaaaaactta
    66541 gcaattatca aaaaattgct gatggattag ctgcaggtta cggagcactg acgaataatg
    66601 aacaaaacag tgtagatggt gttggcttgg ccgtttcaga actgcaaggg atcgcccatc
    66661 tagatgtgga gtatgaagca atttatgaaa atatccaaag tgcttactat ttgctgcaag
    66721 atgcaatcgg cgatatgagt cgtcagattg atttattgga gttagatgag agtcgtttag
    66781 aagaagttac gcaacgttta gaattaatcc gacagttgaa acgtaaatac ggcgaatcca
    66841 ttgagtcaat attggcttac tatgacgaaa tcaccgaaga gctagcttct tctgattttt
    66901 cagaaggtca attggacaaa atgaaagagg aactagagca aaaagagctt ctacttcagc
    66961 aacaagccgc agatcttcat gaagcgcgta aaaaaatcgc aaaagaattg gaaaaatcca
    67021 ttctgcatga attgaaaagt ctgtatatgg aaaacactga gtttgaggta cgtttcttaa
    67081 aagaagaaaa tagacaattg aatcatgatg gatttgacca aatcgaattt tacattacga
    67141 ccaatccagg agagccactg aagcctttgg tgaaagtcgc ttctggtggc gaactgtctc
    67201 ggatgttgct tgctttgaaa actatttttt cttctgagca aggtgtgaca agtattattt
    67261 ttgatgaagt ggatacaggt gtgagcggaa gagttgcaca ggccatcgca gataaaattt
    67321 ctcaaatatc gaaatactct caagttttgt gcatcactca tctgcctcaa gttgctgcag
    67381 tcgccgacta tcaatattat attgtgaaag cagtgattga tggacgtacg caaacttctg
    67441 tttcagagtt gaaaacaaaa gaaagagaag aagaaattgc acgtatgctg gctggaagtg
    67501 agattacaaa actcacactc gaacatgcaa aagaactatt gaaactcgca aaaaggacct
    67561 gagccacctc gcagtggttc aggtcctttt cagcagctga tagctatatt ttatttttac
    67621 atgacactca ttacagcagt caatacaaca gatccaatcg ttaaaatcag cattgtccaa
    67681 atgacaaatt ttgttacttt agcaaaagta cttgtttgtt ttttttcacg cattgttttc
    67741 aacctcgtca ttaattagtt gattcaagtg tacaatcttt tttccatttc cacaagaggg
    67801 cttttttata aaaacttccc tttttttaaa taataggtag ttacgataca aataaataat
    67861 gttaatagaa ctagccatat aaaggcatca tccctttcag caataggtaa cttaatgttc
    67921 attccataga tactgccgac gattgtcggt atagttaaaa taatcgttaa agaagttaaa
    67981 attttcataa tattattcag attattcgat acgattgctg aaaaagtctg attcatttgt
    68041 tctactagtt ttaattgaat gcgagaagta gtcattgcct gctctgtttc caccaataca
    68101 tcacgtaaat gatttttcaa agcatgattt tcttggaaaa gtttattttg cgctagttct
    68161 ttcaatgcat ctaaattagc agaagtcgct tctctgaaat aaacgaggct tttttggata
    68221 tccatgattt gataaagttg tttgttttca gtggatactt gaagtttggc ttccaaagta
    68281 tcgcattgag attgaagcgt agctaaataa ctgttgtaag agagtgtgac ctgccaaatg
    68341 aattgaaaga agatattgag attaggcgaa atatcacttt ttggaaaggt ctggctaaag
    68401 actttcttta aaaacagtgg ttcatgattc gtaattgtga taagcttctt tttgggcgtc
    68461 aaaataatag agagcgggta tgtatccact tgaaaataac cgctaggact tgttttagca
    68521 aaaggatatt gtaacaataa taacgctggc tttgtcaact ttgattgatt gaattcttct
    68581 gtacgggaat tttctgcatc gtccaatatg gaagtgatgt aatctgacgg aatttcaaat
    68641 tgatgtgtca gctgatgaat ctcttcttga ttaggacgtt ctacacaata ccagatcgtt
    68701 tggtcagttt cctttccggt attacgcagt ttctcattat ctaatgtaaa atatttgatc
    68761 atgattttcc tcctgttgcc tgtttctttt attataacgg atagggaatt ggaatacatg
    68821 gaatgtgttt gtaagatata gaatataact gcataaattt aaataaaatg aaacagttgt
    68881 gtaaagtata tacagtatac ttgaagcaac gataaaaaag gagtttacgt tcatgggcac
    68941 attcacacca cttatcttgt tttggtatat ttacccggta atcgttttgt ttggttgcca
    69001 atttcttgta aaattatttt cgttaaatcg tcgttttaaa ataaaagccc ctgatttggc
    69061 gattcctttt ttgtggggcg gtatgcatgc attgtctaga aatacaggga caatttctat
    69121 cttaccgttt ttctttattt ctgttttgct aatgggaatt tgtattgctg ttttccaagc
    69181 atattattat gaagaaatta tttatccgcg ttatttcaag atgacttggc gtttggtttt
    69241 tctgttgaca atcgtcttgt acgctgtctt gatcattgtg aacatacttt cttacctatg
    69301 aaaaaaatag aaaagctgta aaaagtcttt taaaa
//
LOCUS       DBBGRF010000007        66050 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000007 DBBGRF010000000
VERSION     DBBGRF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 66050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.007"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(25..1044)
                     /locus_tag="ACIZD4_000518"
     CDS             complement(25..1044)
                     /locus_tag="ACIZD4_000518"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGC5989476.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(1677..2681)
                     /locus_tag="ACIZD4_000519"
     CDS             complement(1677..2681)
                     /locus_tag="ACIZD4_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC5989477.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(2694..3743)
                     /locus_tag="ACIZD4_000520"
     CDS             complement(2694..3743)
                     /locus_tag="ACIZD4_000520"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC5989478.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFFFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(3760..4581)
                     /locus_tag="ACIZD4_000521"
     CDS             complement(3760..4581)
                     /locus_tag="ACIZD4_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC5989479.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(4568..5347)
                     /locus_tag="ACIZD4_000522"
     CDS             complement(4568..5347)
                     /locus_tag="ACIZD4_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC5989480.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(5364..5834)
                     /locus_tag="ACIZD4_000523"
     CDS             complement(5364..5834)
                     /locus_tag="ACIZD4_000523"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC5989481.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(5846..6265)
                     /locus_tag="ACIZD4_000524"
     CDS             complement(5846..6265)
                     /locus_tag="ACIZD4_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC5989482.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(6346..9123)
                     /locus_tag="ACIZD4_000525"
     CDS             complement(6346..9123)
                     /locus_tag="ACIZD4_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC5989483.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            9314..9538
                     /locus_tag="ACIZD4_000526"
     CDS             9314..9538
                     /locus_tag="ACIZD4_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989484.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            10317..12032
                     /locus_tag="ACIZD4_000527"
     CDS             10317..12032
                     /locus_tag="ACIZD4_000527"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989485.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            12035..13798
                     /locus_tag="ACIZD4_000528"
     CDS             12035..13798
                     /locus_tag="ACIZD4_000528"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989486.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(13838..14374)
                     /locus_tag="ACIZD4_000529"
     CDS             complement(13838..14374)
                     /locus_tag="ACIZD4_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HGC5989487.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     regulatory      complement(14412..14510)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            complement(14697..15119)
                     /gene="mgsA"
                     /locus_tag="ACIZD4_000530"
     CDS             complement(14697..15119)
                     /gene="mgsA"
                     /locus_tag="ACIZD4_000530"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HGC5989488.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            15328..16437
                     /locus_tag="ACIZD4_000531"
     CDS             15328..16437
                     /locus_tag="ACIZD4_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989489.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            complement(16561..17190)
                     /locus_tag="ACIZD4_000532"
     CDS             complement(16561..17190)
                     /locus_tag="ACIZD4_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989490.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17641..18525)
                     /gene="rsmA"
                     /locus_tag="ACIZD4_000533"
     CDS             complement(17641..18525)
                     /gene="rsmA"
                     /locus_tag="ACIZD4_000533"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGC5989491.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            complement(18518..19087)
                     /gene="rnmV"
                     /locus_tag="ACIZD4_000534"
     CDS             complement(18518..19087)
                     /gene="rnmV"
                     /locus_tag="ACIZD4_000534"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGC5989492.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            complement(19080..19856)
                     /locus_tag="ACIZD4_000535"
     CDS             complement(19080..19856)
                     /locus_tag="ACIZD4_000535"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGC5989493.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            complement(20011..21333)
                     /locus_tag="ACIZD4_000536"
     CDS             complement(20011..21333)
                     /locus_tag="ACIZD4_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC5989494.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            21508..22095
                     /locus_tag="ACIZD4_000537"
     CDS             21508..22095
                     /locus_tag="ACIZD4_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989495.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            complement(22574..24583)
                     /gene="metG"
                     /locus_tag="ACIZD4_000538"
     CDS             complement(22574..24583)
                     /gene="metG"
                     /locus_tag="ACIZD4_000538"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGC5989496.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            24851..25129
                     /locus_tag="ACIZD4_000539"
     CDS             24851..25129
                     /locus_tag="ACIZD4_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989497.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            25226..26047
                     /locus_tag="ACIZD4_000540"
     CDS             25226..26047
                     /locus_tag="ACIZD4_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGC5989498.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(26332..27342)
                     /locus_tag="ACIZD4_000541"
     CDS             complement(26332..27342)
                     /locus_tag="ACIZD4_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HGC5989499.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(27354..28307)
                     /locus_tag="ACIZD4_000542"
     CDS             complement(27354..28307)
                     /locus_tag="ACIZD4_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989500.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            complement(28297..29367)
                     /locus_tag="ACIZD4_000543"
     CDS             complement(28297..29367)
                     /locus_tag="ACIZD4_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989501.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            complement(29373..30416)
                     /locus_tag="ACIZD4_000544"
     CDS             complement(29373..30416)
                     /locus_tag="ACIZD4_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989502.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            complement(30417..31358)
                     /gene="opp3b"
                     /locus_tag="ACIZD4_000545"
     CDS             complement(30417..31358)
                     /gene="opp3b"
                     /locus_tag="ACIZD4_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HGC5989503.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            31442..31789
                     /locus_tag="ACIZD4_000546"
     CDS             31442..31789
                     /locus_tag="ACIZD4_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HGC5989504.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            complement(31859..33520)
                     /locus_tag="ACIZD4_000547"
     CDS             complement(31859..33520)
                     /locus_tag="ACIZD4_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC5989505.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            33699..33818
                     /locus_tag="ACIZD4_000548"
     CDS             33699..33818
                     /locus_tag="ACIZD4_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGC5989506.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            complement(34066..34614)
                     /gene="aac(6')"
                     /locus_tag="ACIZD4_000549"
     CDS             complement(34066..34614)
                     /gene="aac(6')"
                     /locus_tag="ACIZD4_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HGC5989507.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            35167..36270
                     /locus_tag="ACIZD4_000550"
     CDS             35167..36270
                     /locus_tag="ACIZD4_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC5989508.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            complement(36267..36473)
                     /locus_tag="ACIZD4_000551"
     CDS             complement(36267..36473)
                     /locus_tag="ACIZD4_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989509.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(36463..37530)
                     /gene="rlmN"
                     /locus_tag="ACIZD4_000552"
     CDS             complement(36463..37530)
                     /gene="rlmN"
                     /locus_tag="ACIZD4_000552"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGC5989510.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(37760..40207)
                     /locus_tag="ACIZD4_000553"
     CDS             complement(37760..40207)
                     /locus_tag="ACIZD4_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGC5989511.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            complement(40396..41832)
                     /locus_tag="ACIZD4_000554"
     CDS             complement(40396..41832)
                     /locus_tag="ACIZD4_000554"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC5989512.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            complement(42151..42966)
                     /locus_tag="ACIZD4_000555"
     CDS             complement(42151..42966)
                     /locus_tag="ACIZD4_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC5989513.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            complement(42984..43619)
                     /locus_tag="ACIZD4_000556"
     CDS             complement(42984..43619)
                     /locus_tag="ACIZD4_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC5989514.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            complement(43638..44279)
                     /locus_tag="ACIZD4_000557"
     CDS             complement(43638..44279)
                     /locus_tag="ACIZD4_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC5989515.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     misc_binding    complement(44324..44669)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            44759..45244
                     /locus_tag="ACIZD4_000558"
     CDS             44759..45244
                     /locus_tag="ACIZD4_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HGC5989516.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            complement(45516..47681)
                     /gene="acm"
                     /locus_tag="ACIZD4_000559"
     CDS             complement(45516..47681)
                     /gene="acm"
                     /locus_tag="ACIZD4_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HGC5989517.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(48176..48475)
                     /locus_tag="ACIZD4_000560"
     CDS             complement(48176..48475)
                     /locus_tag="ACIZD4_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGC5989518.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            48826..49458
                     /locus_tag="ACIZD4_000561"
     CDS             48826..49458
                     /locus_tag="ACIZD4_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HGC5989519.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            49581..50219
                     /locus_tag="ACIZD4_000562"
     CDS             49581..50219
                     /locus_tag="ACIZD4_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGC5989520.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(50338..50410)
                     /locus_tag="ACIZD4_000563"
     tRNA            complement(50338..50410)
                     /locus_tag="ACIZD4_000563"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(50375..50377),aa:Thr,seq:cgt)
     gene            50531..50773
                     /locus_tag="ACIZD4_000564"
     CDS             50531..50773
                     /locus_tag="ACIZD4_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989521.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            complement(50912..51541)
                     /gene="upp"
                     /locus_tag="ACIZD4_000565"
     CDS             complement(50912..51541)
                     /gene="upp"
                     /locus_tag="ACIZD4_000565"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGC5989522.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(51675..52622)
                     /locus_tag="ACIZD4_000566"
     CDS             complement(51675..52622)
                     /locus_tag="ACIZD4_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HGC5989523.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            complement(52775..54019)
                     /gene="glyA"
                     /locus_tag="ACIZD4_000567"
     CDS             complement(52775..54019)
                     /gene="glyA"
                     /locus_tag="ACIZD4_000567"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGC5989524.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            complement(54194..55219)
                     /locus_tag="ACIZD4_000568"
     CDS             complement(54194..55219)
                     /locus_tag="ACIZD4_000568"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGC5989525.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            complement(55241..55420)
                     /locus_tag="ACIZD4_000569"
     CDS             complement(55241..55420)
                     /locus_tag="ACIZD4_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989526.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            complement(55413..56252)
                     /gene="prmC"
                     /locus_tag="ACIZD4_000570"
     CDS             complement(55413..56252)
                     /gene="prmC"
                     /locus_tag="ACIZD4_000570"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGC5989527.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            complement(56245..57318)
                     /gene="prfA"
                     /locus_tag="ACIZD4_000571"
     CDS             complement(56245..57318)
                     /gene="prfA"
                     /locus_tag="ACIZD4_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGC5989528.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            complement(57321..57905)
                     /locus_tag="ACIZD4_000572"
     CDS             complement(57321..57905)
                     /locus_tag="ACIZD4_000572"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGC5989529.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            complement(58011..58259)
                     /locus_tag="ACIZD4_000573"
     CDS             complement(58011..58259)
                     /locus_tag="ACIZD4_000573"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5989530.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            complement(58250..58480)
                     /locus_tag="ACIZD4_000574"
     CDS             complement(58250..58480)
                     /locus_tag="ACIZD4_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989531.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            58586..59188
                     /locus_tag="ACIZD4_000575"
     CDS             58586..59188
                     /locus_tag="ACIZD4_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HGC5989532.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            complement(59292..59861)
                     /gene="lepB"
                     /locus_tag="ACIZD4_000576"
     CDS             complement(59292..59861)
                     /gene="lepB"
                     /locus_tag="ACIZD4_000576"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGC5989533.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(60091..60858)
                     /locus_tag="ACIZD4_000577"
     CDS             complement(60091..60858)
                     /locus_tag="ACIZD4_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HGC5989534.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            complement(60855..61334)
                     /locus_tag="ACIZD4_000578"
     CDS             complement(60855..61334)
                     /locus_tag="ACIZD4_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HGC5989535.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            complement(61459..62196)
                     /locus_tag="ACIZD4_000579"
     CDS             complement(61459..62196)
                     /locus_tag="ACIZD4_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HGC5989536.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            62357..63757
                     /locus_tag="ACIZD4_000580"
     CDS             62357..63757
                     /locus_tag="ACIZD4_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGC5989537.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            63980..65332
                     /locus_tag="ACIZD4_000581"
     CDS             63980..65332
                     /locus_tag="ACIZD4_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HGC5989538.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            65325..66023
                     /locus_tag="ACIZD4_000582"
     CDS             65325..66023
                     /locus_tag="ACIZD4_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HGC5989539.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
BASE COUNT        19015 a        13457 c        11477 g        22101 t
ORIGIN      
        1 gacgattaac tattgatcat ctatttaacg aagagaaaat tcattctcca tttttccgtc
       61 acgtaacatg atttcttttg ctgctttttt gatatcttct ccattataca aaacattata
      121 gattgtttga gtaattggca tctcaacacc tagctgttga gctagctcta ctgctgcttt
      181 tgtcgttgcc acaccctcaa cgaccattcc catgttttct agaacttctt ccagcttatg
      241 tccctgtcct aacaagttac cggcacgcca attgcgagaa tgaacacttg tacaagtaac
      301 gatcaagtcc cccacaccac tcaaaccgat aaatgtcaga ggattggcac ccatcgcgac
      361 accaagacgg ctgatttctg ccaatcctcg agtcatgatt gctgcttttg catcatctcc
      421 gaatcctaat ccatggatag cgccggcacc aattgcaatg atatttttca gtgctgcacc
      481 agtttctacg ccaatcacat cattatttgt ataaatcctg aaataatcat tcatgaacag
      541 tttttgtaca taggctgctg ctttttgatc aatacttgca gctgtaattg ttgtgatatc
      601 atgtactgcc acttcctcag catggctagg accagataat acaacaattg cctgtctttt
      661 ttcttctgga atttcttcag ccaaaacttc tgagattcgt ttatgcgtat cttgttctag
      721 tcctttactt gcatgtataa tgattggctt agtattcatt ttaccaataa gttcctgtgc
      781 gactgaacga atcgcttttg ttggaacaac aaataaaata gcatctgcgt tatccactgc
      841 ttctgccaat tctttatatc cgataatcga ttctgggatc gtcaaatcag gtaaaaaatg
      901 ctgatttgta tgatacttat tgatttcatc aatctgttca ggtacatttc cccaaatacg
      961 gacatcatgc ccgttttctg ccaatgtttg tgctaaagca gtgccccaag atccaggacc
     1021 aagaactgcg attttttgtt tcatggatat tcctccaaat aaataattga taatttccat
     1081 tatagtatac atttcttaaa gttgggacta atttccattg tttttaagtg tttgtttact
     1141 tcttttatcg tttttacttg aaataatcaa tgatatgtta caatagtcta cattttattt
     1201 ttacactcgt tatgctttgc ttgttcctaa gaggaagcag ttttgacaat gttactacca
     1261 gcattactat taggaggtta ggaaacttct cctagtgagt attgatttaa aatacataag
     1321 agacagattg aacatttcta aatctgtcag gtcctgcaac ggacagattg tctctgttga
     1381 cggttgacat aggaactttt gttttagtca acattctgga tacaaaacgc tatgtaaact
     1441 ggcgcaactc gttgtacttg gacttttact acggatccat gcaacaacta aatagtacta
     1501 ttgcataaca aaaaatggtt ggcacccaca tgtcccatta aacagattat aagttgaact
     1561 gtagataatg caaaaaatgt gttttataac gtaattgatg ccaatatttt aaaaaaataa
     1621 agggagcagt tatcgctgct ctctttattt tttatattct ttttatccag tctatcctaa
     1681 taatcaaact gacgatagta gcggcgtatc tctaatggat ggcagttcaa ctgctccaca
     1741 tgagcatcga tgcgttgtgt cactacatgc atcaataaga aagacaaaac acgtccgcga
     1801 tatttttcac tgataccttc tactggatag tcttttgtgt ctatcaatgt ataattgctg
     1861 caaatttttg gcaaaagttt agccacacgt tcagataaca ctctctgttc atcttcgcct
     1921 aaaaataatg tgactggggt tgtttcttct acgatctcta acgtcccgtg aagaaactcg
     1981 gcagcatgga tagatttcga tggaagccag ctttgttctt cccagtaaca catggcatat
     2041 gaataaacag ctccccattg attccctgct ccaataaaat aatgcatact atcacgtcga
     2101 tgtttttctg caaatgataa gccaaatgca tctgcttttt tctctgcttc cactaaccct
     2161 gttggtaaat aacgttcgag ctgttcatag tattctgaat aagcttcgaa ttctccattc
     2221 aaatacatca atcgatctgc tgccataaaa aatttgattt gttctgttcc aggagctgga
     2281 taagtgacca caaaatcgca tagctgagac aacttactgt tcgctttatc gataaatcca
     2341 atcagtgtcg ctcctacttt cttgatttgt tctactgctt tcactacttc ttgagttgta
     2401 ccggtaacag aggacaaaat aacgatagaa tcttttgtta atcttttgtt tccagtagtg
     2461 taatattctg cagcatgctg tacaaagaca ggcaagttgc ttttcccatt catataagtg
     2521 acagcttgca tcgaggaagc atacgttcca ccgattccta gataatagac agcgtcaaat
     2581 ttttccgcat aaagtttatc gatgatttct tctacttgcg gacgtaaagc tagtgcgcct
     2641 tttattgctt tgatttgttc ttcttcattg aatttcagca tgatttccac ctcttataat
     2701 ttacttttca agactgtatc aaagtcttca aaaatctttt tgttcaagtc aataccttta
     2761 gctactgcgg ttttataagc gaatagttga aacggaacga caagcgctaa tacagacaga
     2821 tattcatcac attctattgc taatccaagt gttttctcgt ttcttgcttt ttttgtggta
     2881 atggtgagag tctctccaac gtaccgactc atatatcttt gcaacttttg cgaacgttcc
     2941 ttatttacac tttccccttc aataaagaat agcaaatgcg aagcatctgc ctccaggtat
     3001 gggccgtgca tataagcttc taactcaaat ccttgtgacg gaacgcggat tgtttcagtc
     3061 aatttcgtct ctgcttcttt agctgttccc cagtttggac catatccaat ggtgacgaaa
     3121 cgctgtgcta aacgaaataa actttgatat ccatcaaaaa attcttccgt tttttgaata
     3181 atcgctggta aatggttgat tattttgcgc aactgttgca tgtagtcttg ttctattttt
     3241 ttgctgattt tatttttact tattccaatt cctatcccta agagtagtaa ctgtaaaaca
     3301 gtcgcagaat agccttttgt aacgaagcct actgattcta ccccggcacc taaatcaata
     3361 atttgtgcag cttctaaagc aagtggactt tgcacgtcat ttgtgatagc aacaacaggt
     3421 aacccttgtt tttgtatcat ttttactgct tcaacagtag aagcactttt cccgctttgt
     3481 gacacagcaa tcacagtatc gattgaagga gaaagttttc cataattgaa aaaaaaaaaa
     3541 ggttcttgaa tatcgacagt aagatcacca taagattcca atgctggctt cgctgctaaa
     3601 caagcgttat aagatgaacc cgttgctaag atcagtaaat tcactgtttt tttcatatgt
     3661 tctcttgtcg aaaaatcatt ctttttcaag atcgtactta gtacttcctt ttcttcatag
     3721 atataatctt gcatcgtaaa cattttctct gctccttttt taaaaaatcc ctatccacga
     3781 accaaaaatt ccaaagaaag ctagtccgat caagatcgtt aatggtttca cttctttctt
     3841 caatagataa aacactatgc caaatgctcc aagacataag atatttggaa cgatatcatc
     3901 aaaaatactt tgaacagtca cagcattttc tcctgaaccg atttttaaag gaatattgat
     3961 ggtgatcatc gtggcagtca ttgctccaac gaccatcagt ccaataatag acgcgcctaa
     4021 tgtcaaactt tccatcatac cgtttgcctg gatctttttc aaaaaacccg ttcctaagcg
     4081 atatccccaa cctgttgcta gatagcgaaa cagaatgtgc ggaatattga aaatcaaaat
     4141 gaacaagata gggcctaaaa tatttccttg catggctaaa gaggtaccca cacctgtggc
     4201 aatcaatcgc aaagttcccc aaaagaaaga atctcctaac cctgcaagag gtcccatcaa
     4261 agatgttttg atactatcga tcgcagtcac atcaaattca ggatcatcct tattttcttc
     4321 ctccattgca gccgtgattc ctaaaatcag tgtaacgata tgtggggtcg tgttaaaaaa
     4381 ctctagatgc cgtttcaaag ctgctgccat ttcttctttc gactgatata actttttcaa
     4441 aatcggaatc attgcataaa cataagccat attcatctga cgttcataat tccaagaaaa
     4501 ctccatttga aaagaacgcc aaaatacgtg atttagctct tttttcgtta ttttgctgtt
     4561 tttgatctca gaattcttca tcttcttcta cctcccctgc agttgtttga agtggtagtt
     4621 gacggacatt cataatattg actaccacaa ctgctaaaat cgcaccaaaa atagctactc
     4681 cggtcacagg aatctctaag taagaagcta tagcaaaacc taagaaaaaa tatggtgcaa
     4741 cttgtttgtt gatcagcaaa cgagcaagca tcgcaaaacc aagagctgga atcaaccctg
     4801 tagctactga caaccccttt tgaacgaagt caggaatcat atttaataga tttccgatcg
     4861 tattgcttcc caccatataa gaaaccatta ccacaacacc aagcatcaag gaaagaccga
     4921 taccggcaag caagtgcata tgctcgactc ctttataatt tccttcttct gcataattgt
     4981 ctgctttatg gttcataatt ggaatcaaaa gccctaagta aatatttttc aatatcaatg
     5041 tcaacgtagc aatcggcaaa cctagtaaaa gcgcggtttc tgtaccggct ccagctgtaa
     5101 tagcaaaagc cgtccctaaa atcccaccgg tcacaacatc aggtggaatc gaagcaccta
     5161 ctgagaacga tccgataaat gctaactcta aagttgcgcc cataatgatc ccagttttta
     5221 catcacctaa cacgattcct gtaaacagcc ccgtcacaat cggacgagaa agcaacgatg
     5281 tccctagtgc atattctgat tgtgcgacaa atgcaacaat tcctaataag actgcttgta
     5341 caatcattga ggttcttcct ttcttacaaa acttctctta catccacttt tttatctgct
     5401 ggtacttgac ggatttctac ttctatttgt ttgtcaatta atcgtttcaa gcgttcctcc
     5461 tcttctggta aaatatttac cgcttttccg atgctgcgag taccaggttt tgccttgatc
     5521 cctcctaagt tgatggtttt gatttctgga tacgcttctg ccagcttata tgcatcctcg
     5581 atcgattcca ctacgatgaa taacttatat ttatctgtca ccccgctttt caacgcggca
     5641 atcgagtcat caattgattt gatcactagt ttgactcctt gtggcttggc taatttgatc
     5701 gttgtctttc gtatctcatt cgtaggtaca tcatcattag caatcaaaat acagtctgcg
     5761 cctattgttt gtgtccatga aaaagctact tgtccgtgta ataaccgatg gtcgactctt
     5821 gtcaatacaa tcatttttct tcctcctaaa attcgtcttc ttctattttc tgattgagcc
     5881 gctcgttaca aaactggatc attttttttg aatcagttag cacctgctgg atcaaaacag
     5941 ttgtctctac ttcagcgtcc aaccgagata ctagctcaat caatagtggc aaattcaatc
     6001 cggcaacgag atagacatga tcccgattga tatattgtaa gaattcgttg ttgacacttc
     6061 cgccaaaaag atccgtcaga acaatgattt ctttatcttt gtacctcata aaaagctgcc
     6121 ttactgtttc cgctaaatca aaattctcat cagtatagca atcgaataca gtaatagaat
     6181 gatttttccc atagatcagc tctaatgaat ctaatatccc tgaagcaaat tttccatggg
     6241 aagctaagat aatttctcta tccacttttt catctcctct tttcacttac acatactaaa
     6301 aaagcaagtt gcatgccaaa attagtggca acaacttgct tatgttcaaa attcttcttc
     6361 tatcgagaga aactctgtat cttcactcaa aatatcatag atataggcaa tctcagaatt
     6421 ggggatcatg acactataat gctcttcaat gacactaaac gcagatttaa tagcagataa
     6481 cccttctttt tgacactgct tccatttctc taatccttga taggtttcga ttggcatttg
     6541 tcggatcaat cgttcaatga gacagctcac atggacatac aacgctaatt ttttgggatt
     6601 gctgatgctt cgattcaact gcacctctaa ttctctcata aaatgatcga tttctcccat
     6661 caccttctct gtatctagaa tagtcacgga atccagtact ttttccaatg aaaaattacg
     6721 aatgatgcgc tgattgaata tttccttctc tgaagcattc atagtagtgt ccaaccattc
     6781 agctagtaca gacatctttt cccccgagat gaggtcttct aatgaaagat agtcgatatt
     6841 ggtgatatca ggatctgtgg tgccaatcat tcctacgact tcgtatatgg aaaataatgg
     6901 gtcactgttt ttcttatctt ttaattgctg atattcatat gggatgattt tcaactgaca
     6961 agccgtaggt aagctttttt ctagcagttc acttaagtgg accgccgtac cgattccagt
     7021 gaagcaagta gtaatgagtg ctttgggttt gttttcctct ggatagagca gtcgccattc
     7081 tggctggatc tgtcgaacag tctcttctgc tatctcttct aatgatacat ttttttgcag
     7141 gcattcccct actgtgattg ctaaaggtgt cgtcacatta ttcaaaatca aaagcggtac
     7201 ggataactgt tttttaaaaa actgatggat ttctttcaga gatcccatgt ctactaatat
     7261 gatcaatcca tttgaaacat cgctgttttc gcaataatca aggatttctg aagcaatctg
     7321 ctgtggtgtg acatctagtg gcatatcaaa tgattcaaat agatcctctt gtaataaacg
     7381 atttactaca tttgccatac tgctagcagt tgcataaccg tgagcagcaa tcatcgcttt
     7441 tggcagtcgt ttttcttttg accatttcgc tttttttaga tagatcgtca gtaaaatccg
     7501 atccatactt gtgtcttcaa tatctaattt gatcttactt aattccagaa ttcgttggac
     7561 atagtgataa ctagatggat aagactgaga aacttgttgt tctaattctt tgattagttg
     7621 gataatatca tgttcttccg gtaaccattt gatagtgctt cgctgataga gatagtaact
     7681 caaggcatag acactgtttc catcgaattt gatttgatag gcagtttcca tttgtcgaaa
     7741 ggtctctcgg atagattgtg tccaataaac cagcagctcg tgtttttctt gtctactggt
     7801 ctcaaacagc aaaaaatcaa ataattgaat cacttcttgc tttaattttc cttcgcaaga
     7861 atatagcaga cagttatttt tcttgaaatc aattaggatt tgctcaaaac ttttaacgat
     7921 tcgctgctgt tcgggctgtt gcttctccat taattgctct aaggtctggt cttgcgtaat
     7981 atagattcct tgctgtgctg tatttttagt aataggctgc gcaagtagtt ctttttgcaa
     8041 atgatggatc gtgacatgga tttcaggctg ttcacgctgt tcagcatatg cttttgctgc
     8101 tgaaactttg acgatatttt tcagctctcc tatgtttccg gataatttct gacttgttaa
     8161 aagtgacaaa gctggtccac tgactgacaa agggctcccc atttttcttt gttcttcgag
     8221 aaaaaaagag taaatcagtt ctagccgttc attacgacta cgctgattaa gtgcaggtag
     8281 ttcgattcgg ataggtattc ttcgaatgaa agttgttaag aaatgactag taatctcttc
     8341 agtcgtagca aaaaagagac gtgttttgat ccggcgtgac aaattaggtt ctcccatacg
     8401 ataaatcaca ccttgatcaa gataggtgaa cagtttttcc tgaccttctg gtgttaagcg
     8461 atgtacctcg tctaaaaaca agatcccacc atctgctgct tcaaaagccc cttttttatt
     8521 ttcttctgca ccagtgtacg ctcccttaac atgtccaaac aaattgctag tcaaaagttc
     8581 aggattatct gcatattgtg cacaattaaa agtgatgaat ggtgcagaat cttctagcag
     8641 atcatgaagc agacaatact gatagaccaa attaactaaa taacttttac ctgtgccact
     8701 ttcgccagta atcaaaagtg gtaatccgcc atctggatag taaagagctg ttttgatttg
     8761 ttcgatactt tctttcaaac tggcgtcgta tccgatcata aaagagaata agtcttttgg
     8821 ttgcgcgaaa aaaggctgtt cctctttgag atcatcgata gaaaaataaa aattcgtgcg
     8881 taacttaaaa aattgttttt caaaagcttc tttgtggaaa taaatcactg gtcgagaatt
     8941 gattttgact agtagttgct catcatttaa ctggttcaaa taatgactga ctgtgtttct
     9001 ttttacccca aaatgatcag ctaacctttg tgctgtaaag acctcgttca tatgttctaa
     9061 atcgaaaaag gctgtctggt tctctaagta acataaaatt tccttcttca acaacttatt
     9121 cacccctcct ccatcataga aaacggattc attttgtcaa taaaatcttt aataaagaat
     9181 tgaaaaatat atcttattat agacagcagc ctacttatcc cttataattt ttattctaaa
     9241 aaacgtacag ttccttccag tttttatact ggaatttcaa catatgaaag aataaggagg
     9301 ctatgactat tcaatgaaat cggataaata taaaaacagg aaacatactt cctggaaaac
     9361 ttttcgagaa atcatcggat cttatctcgc tgtagttgta tttttgcctt tgctttatat
     9421 ggctatgaca gaacaaactc gttttattgg cgtagatacg caatatatag ccgaaacagg
     9481 atttttattc atctttatct tgatttttgc gttctataaa tccttccata caaaataaga
     9541 ttcacagatt tcaactttcc tgtctgtttt tagctattac aaatccttat atgtggtata
     9601 acaacaattt attggcataa tgaggaaaaa cgagttatga tgctttcaga gagtaaagag
     9661 gtactgttgt caccatcctt tttattgatt acgtacacca ctcttagttt tttcccattg
     9721 attacgaaaa caaggtagaa acattgatgt tcctaccttg ttttcttttt ttattttcag
     9781 atcaaaatct caagtagctt ttgacttgat gtcgggaggt tgtcttcgtt ccatcaaacc
     9841 tgatagaatc tgcgccaaac catagttttc tccactatta tttattcctc taagatagta
     9901 cccacaataa acgaataaat atttttctca ttttcatact ccttctttga aaatcaatta
     9961 gatttctctc aacccacttt tttacaaaaa ttacgtagca aaaaagattg caagaacaaa
    10021 ttaaaaaaga agtaaataga gtttcatcta taaacattta cttgatatat tttttatgca
    10081 gaattcattt atagaaaaat taagtaaaat agacgttcct atgaatgaag agactggcat
    10141 gttttctcat tttctttttt ttaaaaaaaa tagtctattc aatttctaaa gcttcttcat
    10201 aataaaactt tcatttatga aaaggcttgt tctcttttca ttctaaattt cctaagctac
    10261 aatgtggtag tacttgtttt ttcaattgtg gacaaataaa taataggagg aatcatatga
    10321 ttcagttatt acgttatgca aaagactatc gtaagcaaat cattttgggc ccgttcttca
    10381 aatttcttga agctgtcttc gaacttgtcc tgcctttaat gatggcttcc ttgatcgata
    10441 atggactaaa aatgaatgac cgaggaaaaa tcattgaaat gggcttatgg atggtcgcta
    10501 tgtctgtgat tggtctgatt tgtgctatca tttgccaata ctatgcttca gtagcttcac
    10561 aaggatttgg tacagagtta cgtaatcagc taatcaaaaa aatcaatact ttctctcaca
    10621 acgagttgaa tcattttgga acagatacct tgatcacccg aatgacaaac gacatcaatc
    10681 agcttcagct agctttagca atggtcattc gtttattgat cagagcaccg tttttaagta
    10741 tcgggtcagt ggtcatggct tttgtgatcg actgggaagt aggtctgttt ttcttagcat
    10801 tattgcctat tttctcaatc attttatttt ttatcatcaa aaaaaccgtt cctctctacc
    10861 aaaaagtgca agaaaaacta gatcagctca atgaacacgt tagtcagaat cttagcggtg
    10921 ttcgtgtcat ccgcgcattt gcgcagacaa aaaaagaaac agagaagttc gataaaagca
    10981 caaatgatct agcgaacaat tatttacgtg tttccaatat ctctgcccta ttatcacctg
    11041 ctacaacctt gatcatgaat gtcgggatca tctgtttgct gacagttggc gggatcaaag
    11101 taaatattgg tagcttgcaa caaggacaag ttcttgcttt gatcaattat atgaatcaaa
    11161 tgcttttggc actgatcgtt gtttcaaacc tcgtcgtgat cttcacacgt gccgaagctt
    11221 caggaaatcg ggtgaaagag gtgctagaca cagaaaattc gattcttgaa gctgaggtca
    11281 gtactactcc cgatttttct tctgaagcaa ttatcgcttt tgaccatgtt gacttccgtt
    11341 atactcctga ttctggtctt tctctccaaa atattacatt tcagctgaag cgaaatacag
    11401 tccttggaat cattggtcca accggaagcg ggaaaacgac tttgacacaa ttgattccgc
    11461 gtttctatga tgtcagttcc ggtacagtta taatggacgg aatggatgtt cgttcttggc
    11521 agctggatca tctccgtcag caaattgctc ttgttcccca aacttctgta ctatttaccg
    11581 ggactattcg tgaaaacctt caatggggta agaaagacgc cacagaaaaa gaatgttggg
    11641 aagctctgaa aatcgctcag gcagaagaat ttgtccgtca gcttccaaat ggtttagata
    11701 caaaagtcat ggaaaatggg aaaaatttct ctggcggaca aaaacagcga ctgacgattg
    11761 caagagcttt gattgccaag ccagcattac tgattttaga tgactcttta agtgcgttgg
    11821 attatcaaac agacttggat ttgcgtaagg cgctacagac ttatcttggc agtacagtga
    11881 ttattatctc ccaacgtgtc cgctctattc aagaagcaca tcatatctta gtgatggatc
    11941 aaggtaagat tgctgctcag ggtacccatg aagaattact tgctcaatca gcagaatatc
    12001 aggaaatcgt cgcatcacag gaggaagaat agttatgaaa gtaaaaaaat tatccttgca
    12061 gacgctccgc cgattcattc cttaccttac tgcctatgca aaagacattt ggctagctgt
    12121 gatactagga atcatcaatg ggattgcaac agttgtgatg acgttacaaa ttggtcaaag
    12181 tatcgatcaa atgattggag aaggacaggt ccgcttcaat cgactgttcc atttacttat
    12241 tctattcggt ggtatcgttt taatcaacgt agtcagtcaa tggctcatcc aagtgttaag
    12301 caatcggtta gcttacttat ccgttgcaaa attaagaaaa gatgcatttg ctcatctgaa
    12361 tcgattgcca cttcgttatt atgatcaaaa ctcccacgga aatatcgtca gtcgatttac
    12421 aaatgatatg gacaatattt ccattgcaat ttctgcggcc ttcaatcaat tattttctgg
    12481 agtggcaatc atcattcttt cgtttatttt tatgatgcgt ctaagtccac ttctgacatt
    12541 ggtcgttctt tgttctacac caattatttt ccttgtgagt tggatcgttg ctcgtgcttc
    12601 acaaacaaat ttcgatagac agcaaaggat tattggggat atctcgggct ttgtgaccga
    12661 acgaatcggt aaccagaaaa tcgtgaaagc ttttcagcaa gaagaagcta gtcaacagca
    12721 atttgaactg ctaaatgctg atctatatga aaaaggacaa cgggcacaat tttcttcttc
    12781 cttgacaaac ccgtcttctc gttttgtaga tcaccttgct tatttatcga ttggtttagt
    12841 tggcggccta ttggcattga agagtggttc gtcaatcact gttggtgtga tttccagctt
    12901 tacgatctac tcaagtcagt tttctaaacc atttatcgaa ctttctggaa tcacgacaca
    12961 actgcaaacc gctttttctg gtctagaacg agcatttgat ttgatcgatc agccagaaga
    13021 aaagcctgat ttgccagatg cctatgcctt ggaacccaaa aatatcaaag gaaaagtctc
    13081 ttttgatcat gtttcttttt cttatgaccc caagcagcgt ttgatcgaag atttcaattt
    13141 tactgcttat ccaggtcaaa ccattgctat agtaggaaaa acaggggccg gaaaatccac
    13201 acttgttaat ttgctgatgc gtttttatga cacaacaaaa ggaacaatta cagtcgatga
    13261 ccatgacatc cgctctatcc aacgtgatac attacgtaaa agttttggaa tggtgttaca
    13321 agatacttgg ctatttgaca gtacattgcg agaaaatctt cgttttggga atccggaagc
    13381 aagtgacgca gaaatcaatg atgccctaaa agcctcttat atgtatgaat ttgtagaacg
    13441 tttgccggaa aaattagata ctaagattgg cggtcaaggg ttaaagatat cagatggaca
    13501 acgccaactg ttgacgattg ctcgaacgat gatcagtaat ccccctatgt tgatcttaga
    13561 tgaagctacc agctcagtcg atacattgac agagaaaaaa atccaacaag ccttcttagc
    13621 aatgatggaa ggaaaaacca gttttgtgat tgcccatcgc ctgtccacaa tcaaaaatgc
    13681 ggaccagata ttagtgatgg atcagggagc tattgtcgaa atgggcaccc atgatgagct
    13741 gcttcaaaaa gatggttatt accgacggct ctatcaagca caattcacag cacaataaaa
    13801 acaagcagtc ttctgggatg ggaagactgc ttgtttttta tttagcgtgg atcgctaaac
    13861 ttcttaaaat ttttttgtaa ggaatactac gtcctacgta ataaatggca attgattgaa
    13921 tcggtaacca tattactgtt tttaacaggc ggggcgccca aacgacccag ctgaacaatg
    13981 gcacatggta catcaacgca agccataatg gtgtcaaaaa taagttgatg atcagcgtga
    14041 cactaagcgt agccagaatg gcatttttcc aagtgatctc ttttcgatag aaaaagaatc
    14101 cgtagattgc tccttcaata aatgcattca atgtaaatcc aataaagaat gcagatttcg
    14161 agaagagggc cattcctact aaatcagcta aaactgcgcc tatccctgac caaaaaggac
    14221 caaaaagaat gcccatgatc acttgtggaa taaatgtgac actgatttta ataaatgggg
    14281 tctcgattgc taccagtcgg gacaaagtga ccatcaatgc aatcaataag cccataatag
    14341 caatcatacg tgcgtctaac cggtgtttct tcatttttag catctccttt aagagctgct
    14401 acatcgtatc atgcagcgaa tgcgaaaata aaaccgcgaa cattacgtcc ttcgtccaag
    14461 aggcaacatc ccatcctctt agcacttaac gctttatttt ctactctgta ttatttttgg
    14521 gatcttttcc cacagaaact atagcatatt ttcacattta ctgcaaatac gaaaaactaa
    14581 tattattgtt tatattatcc aatacgttcg tattatatcg catattatca gtttgtttag
    14641 cttttatagc tacatatagg cgaacattaa acgttatttt tccatacgct tatccatcaa
    14701 aatgaaagtg gatgcttgtc tatttcatgg acgattcttc gaaaatctag gaagccggct
    14761 tccagtcctc ttagtagcac ctcagctgtt ccgatattcg tagctaacgg aatctcatag
    14821 acatcagata aacggataag tgctgttaca tctggttcat ggggctgtgc agccagcggg
    14881 tctcgaagaa aaatcaccaa atctaactga tcctccgaaa tcatggctcc aatttgctga
    14941 tccccgccta acggtccgga tttaaaccga tggatcggca agccggttgc ttccgtgatc
    15001 ctctgcccag tcgtcccggt agcaaaaagt tcatgttttt ccaatattgt tttatacgct
    15061 gttgctaatt tcaccatcat aggttttttt cggtcatgag cgatcaaagc gattttcata
    15121 agagacactc cttttgatat tgttaacata cttatttact ccagtgtatc agtttttatt
    15181 tcttatggat atttattaaa gcttaaaact agcacattga caaaaaaaag aaaaaattct
    15241 tgttcaacat gacattgaag ttagttaacg ctttcattta tactttaaat agttaataaa
    15301 actaaaaaag aaagtgtgga acgtattatg gtagaaatgg ctctgaaaaa cgtatataaa
    15361 aaatatgaca atgcagaaaa ttattctgta actgatttta atctatcaat caaagaccgt
    15421 gaatttatcg tttttgttgg tccttccggt tgtggaaagt caactacttt gcgaatgatc
    15481 gcgggactgg aagatatctc tgaaggagaa ctaaatatcg gcggaaaagt catgaatgac
    15541 gtggcaccta aagaccgtga tattgccatg gttttccaaa actacgcatt gtatcctcat
    15601 atgactgttt ttgataatat ggcttttggc ttgaaattac gtaaatatga taaagcagac
    15661 atcaaaaaac gtgtggacaa tgcagcagag atcttaggtc tgacagaata cttgaaacga
    15721 aaaccagctg ctttatctgg tggacaacgc caacgtgtgg cattgggacg ggcaatcgtt
    15781 cgggatgcaa aagtcttctt aatggatgag ccattatcaa atttagatgc taaattacgt
    15841 gtagccatgc gtgctgagat tgccaaactt caccagcgtc ttgaaacaac gaccatctat
    15901 gttactcacg atcagacaga agcaatgact atggctgacc gaatcgttat catgaaagac
    15961 ggatttatcc aacaaatcgg tacaccgaaa gaagtttatg atacacccgt caatatgttc
    16021 gttgccggct ttattggatc tcctgccatg aacttcttta atgtgacatt gaaaaatggt
    16081 gttatcacag atggacatgg gcttaagctt cgtattcctg aaggaaaaaa caaagtatta
    16141 gttgaaaaag gttatgaagg aaaagaagtt atcttcggta ttcgtccaga agacatccac
    16201 agtgaacaag tagcccttga agcttcacct gaagccgtag tgaaatcaga agttgtcgtt
    16261 tccgaattac ttggagctga aacgatgctt tacacaaaaa ctggttctac tgagttcatc
    16321 tcaaaagtag atgcaagaga tttccataaa ccaggcgaaa tagtcgacct tgccttcaac
    16381 atcagcaaag gccacttctt tgataaagaa acagaacaag tcatcaaact tccataaatt
    16441 gccccctgtt agagctgtgc cagaagatgt tggtgcagct ctttttagga caaaaaactc
    16501 tcatcttaga ggatttatta tccattacta gatgagagtt ttttttttga gagatcatgt
    16561 ctaatatgtc gttttcttcg cgtacccttg aatcgactct ttccgatttt ctttttttgc
    16621 tgccgtaaat acggggatat caaaatattt gctgagtgtt cctgctataa aataagcaat
    16681 attataatca actaaactgt ggataagccc accaatcccc atcaagatga atactgtata
    16741 aaaatatcct tgagaataat atgtttcagg catattacca ataaagtaaa agatgctgac
    16801 tactagcatt tctgctaaag aatgaatcac accgatcaca aaattgaacc cttggaaacg
    16861 ccaattagca aaagtaaact gtccattttt taaaacgata ctcggatgct tttgcaagta
    16921 ccaagcccca atcaacgcaa acacaagatg tgacaatgct cgcaatgcga tgataaccgg
    16981 cgttgttaaa aagaaaccaa atgtcgtacc tagcgcaaca gccactgcaa ctcctggtgt
    17041 aaaaaacatc gcaataaata atggcacatg agacgccaaa gtaaaggaag ctggtggaat
    17101 catgatttta ggcatgacca ttgggataat gacccccatc ccaatcaata aagcagaaat
    17161 cgttagtttt cgaactgaat tttttctcat tttttctctc tcctaatatg tcttgacaca
    17221 taaatgtcga cttagtataa ctcacttact aataactgtc aagacacata ttcttttcta
    17281 aatccataca aaatgagtgt gagtatcaag tataagaatt ttttgatcaa gaaacaaaaa
    17341 taggagatgt gacaaaattt gtgtcacatc tccttgttcg gcataatagt ggtcaaaagc
    17401 ttgcatcaag taataagacc aactaactca aaaacatgag aagctgtttt ttgaaattgt
    17461 tccttgtgac ttagagttaa acggcaggcc cacaacctct ttcttaaacg gtgttcaaaa
    17521 gcttgcatct gcggtaataa gcccaaacaa acgaaaaaca tgaggaacta tttttgtttg
    17581 gctgttctta ttacttgatg caggacagct ttttcacaac ttctgtcaca acctcttttt
    17641 ttactgcata ttttctgaca tcgcattgct taatgcggcg aattcttgta atgacaaagt
    17701 ctccccacga cgttttggat cgattccagc tgtttccaag ctttttgcta accatgcttt
    17761 tgtctggtca tctttgccat acgaatgctg caagttattc caaagcgttt ttcttctttg
    17821 ctgaaatgcc gcttttgtca atcggaaaaa tgctttttcg tctgtcactt cgactgccgg
    17881 tatatctctt cttgtcagtt tcaaaatcgc tgaatctaca tttggctgag ggacaaatac
    17941 tgtttttggt acgatgaatg ctaaactggc ttccatataa tattgaacag caatcgataa
    18001 tgaaccataa gctttcgttc ctggttcagc agagatacga tcagctactt ctttttgcat
    18061 catgacgact agttcatcca caaccaaatc tgattcaaga aaatgcatca tgatcggtgt
    18121 cgtaatatag taaggtaaat tcgctacgac ttttaacgga agctcctcat gaaatgtttc
    18181 tctaacagct gttgacaaat cggtctttaa aatatcttga tgtacaatag tcacattgtc
    18241 atagggttgc atcgtatcag ccaatacagg gatcaaacga tcatcgatct caaatgctac
    18301 gacttgtttt gcatgcttgg ctaattgttc cgtcaatgca ccgattcctg gtccaacttc
    18361 gatcacgttc gtatgttcat ctatttgcgc agtttctacg attttcctta aaatatttgg
    18421 ttcagtcaga aaattttgtc ctaaactttt tttaaatgaa aaaccatgtt tcaataaaat
    18481 ctcttttgtt ctagagggtg tcgcaatttc acgatattca ctcatgttgt tcctccacta
    18541 ttttcattgc ttgggcgagt tctttcggcg taatacgaaa catcttcaaa cgtttttcca
    18601 attgtttgcc gttcgtgtaa ccgatgcgca actcgtcacc tagtttttct cgtttttctt
    18661 ttgcttgtgc cccagctatt aaaccatagt ctaaaaggtc ttgtctagtg atttcagaaa
    18721 cagccgtttg ggaaatgtct ggcgtcacga cctttttcaa tgcttctaaa atagcagcat
    18781 cacttgcatg ctcgacacca aggcttccct ttttctttgg tttagcttgt gtgcgcggca
    18841 aaaaagcatg ttttgcctga ggaacagctt ccataatgat ttttcttatt ttttctcctg
    18901 aaaaatcagg atcggtaaaa acgatcactc cacgagtctc ttgggcatgt tcaatttgca
    18961 tcaggatctc ttcattgatt gcagacccta ttgtttctat cgtatctgca tcaactactt
    19021 cccgcagcct tcttgtatcg tcttttcctt caacgactat aatctcttgg atcttcatct
    19081 tatccatgtt cgcttagacc aaataatcgg tgcgcatttg tccatgtttg ggcagccact
    19141 tcttctgtcg gaagattccg aagttcagca atcttttcta ctgtataacg agtatagcct
    19201 ggttcatttc gctttcctct aaaaggaact ggtgccagat aaggggcatc tgtttccaca
    19261 agtaatcgtt cgattggtac atttgctgca gcctcttgga cgtctaatgc ttttttgaaa
    19321 gtgacgacac cgctaaatga aatatgcatc cctaagtcaa gaaatcgttt tgcccattca
    19381 taatcaccac tgaaactatg catgattcca ccgatatctc gaacatcttc ttcttttagg
    19441 atttgatacg tgtcttcaag tgcttctcta gtatgaatac tgattggtag gttcatttct
    19501 tttgcgatag caatctgtct gcgaaatact ttatcttgga cttctttcgg gtcttccatc
    19561 caatgataat ccaagccaat ttcccctaat gctacaacct ttggtaaagt caattgttct
    19621 tgtaatttat tttcgatttc tttcgtataa ctgccagcct ctgtcggatg ccagccgata
    19681 atactgtata tatttggata gtcatggctt aattgcaaag acttttcaat cgttggcgta
    19741 tcgaagccca cgaccgccat tttcgttacc cccatttctt gtgctcgctg aatcgtttct
    19801 ggaatatctt cattgaactg ttcagcattt aaatgggtat gagaatcaaa tatcatgttt
    19861 atctctcctt ttcattctta ctttagcaca taagcactac ttgcagaagt agcaaaaatc
    19921 aaaatagaag aacttgtttt attgaaatag aaaaagcacg aagatctaga ggacctagtt
    19981 cgtacttttt ctgtctgttg ttgaaatatt ttactcttct gagcgttttt tctttttttg
    20041 ataatagact gggataccta tcaaggtaac acctataccg atcaatgcta atttcgtttg
    20101 cgtcatcatc gtcataccta aaatgaaaat agcaccgaga atcgcaataa tcggaacgat
    20161 tggataaagt ggtactttat atggacgtgg caattccggc gctttttttc ttaaaataaa
    20221 gacaccgata aaaatcagta aactgaatag ccacatcaca aaaatcaaca tgtctgttaa
    20281 aaagtcgaaa gaaccaaggc tcatcataat acaagctact gctaactgga aaaccgcagg
    20341 aacataagga accgtaaact tctttgaaag ctttgtcagc tgtttactga aaggtagctc
    20401 gtcttctaaa gccatcgcat aaggcacgcg gatcccagtt agtgtataac cgttcaatgc
    20461 accgtatacc gagatcaaga tcccaatagt gaccagcttt ccaccgattc ctccaaaaat
    20521 gacgtctgat gcttcagaag ctgcattcaa attaccggca agatgatcaa tcggcaaagt
    20581 tttcaaaaaa acaaaattga tcaatagata aacgactgtt acaaaactca aaccaagaat
    20641 aattgcttta ggcaaatctt tttccggccg tttcatttcc cctgccattg caccgacacc
    20701 taaccagccg tcataagcaa acaacgttgc taacaacgca ctgctcaatc cttcgacaaa
    20761 agtaacatct tttccagctt cgattggaaa taactggaca gttccttgtc ctggggtcaa
    20821 taatccccat atgacaatca cagcaattgg tattaattta acaatcaacg tcactgattg
    20881 tacagaagca ccgacttttg tccctaacaa attcaaccct gtcacagaaa cagcggtgat
    20941 cactgcaatc aacaaaagat aatcggtaga taattgtaat aagttcgtca attgtgtcgc
    21001 aaagataatc gataatgcag caatattagc aggaaagtaa atcaagcttt gcgcccatcc
    21061 taataaaaag ctgggcaatt ttccatacgc agcttcaata tattttacag ctccaccagt
    21121 ttccgggatt gctgtagcta attcagccac tgtcaatcca gcacagatcg ttaagaaacc
    21181 acccaaaagc caagctagca atgtcaaact tgtagactga gtactagcag taacagcagc
    21241 agttttgaag aagacgcctg caccgatcac ggttcccata acggtagcta atgcgccaaa
    21301 cagattgatt tctcgtttta gtttgccttt cattcccatc ctctttcttc tttgaaattt
    21361 ggtataattt tcagtataac tgagaatatt ttaatttacc attctttttt ctccactttc
    21421 agtgaaaaac tccctcttaa gacggatgta tttctttttt atttttcgta tactaaacct
    21481 accttttcca cgaaggagga acagtttatg gattttaagc gttcttatcc gaaattagca
    21541 gattatttat ccaaccgggt cgatttttcc cgtaaagaac aacagcagtc ccattggcat
    21601 tggttcacat taattttatt tggattaatg actgttgcaa cgttatcaca aaaactaata
    21661 ttgctgactt tgttcatcgc aatcgttgca ttgatcaaag gtcctgtgat gatcttgtgg
    21721 gggatgttgt attccttttt ggttgggctt tttccgccta tcggtatttt gctttcagcg
    21781 attttctttt tattgaatat cggaacattt acaaagaact ggcggatgac cttagtcggg
    21841 atctattttt atttctatcc ttttggagtg atggcactta gtgaagtcat gcattgggat
    21901 aatcattggt ttatagctgg ctccttgctt ttagggttga tcttgttaca cgtgatgttg
    21961 acaaagctct atcaacatta tggtatcgga cgtacgattt tctggtatgt cttttcgatc
    22021 ccatttgcac tgcttactgc tctcttacca agccgtttga agacaaaaat aaaaggttac
    22081 cataaaatca agtgatagga tttttacaaa ataaagaaaa caatcatcga agtcaaagcc
    22141 gatgattgtt tttttatcta tattttcaat cacacatata agagcacaaa ctaattgaac
    22201 ataaagtgat agaacttata attaacacat caacgctact gttagatata aatatagatg
    22261 taataaagtc attgcattca aactttatga atgtaaggac aataaaaaag agtaccagat
    22321 gaatcaatta aaatctgccc gaccctttat cattatgctt tttttctgtt tttacgattc
    22381 ctattagtat tattctaaat taacaaaaat cagcgaagct cgtacttctt tttctaggat
    22441 ttattttgga tagttctctg tttctgtatt atatgattgg cttcaagtaa taagaaggaa
    22501 tttacgaaaa ttgcttctca aatttcggaa aaagggggta tgacacaact agtgtcatac
    22561 cccctttgaa tttctatgcg atttctgagc catttggcat ggattttggt gcttcgatta
    22621 cttgtaaaga gccatctggt gcttctgcag aaaggatcat tccttgactg atttgtccac
    22681 gcatctttcg tggtttcaga tttgctacaa tgacgacttt tttcccgatc aattcgcttg
    22741 gatcaggata aaattcagcg attcctgaca agatttgacg gtcttggctg tctccagcat
    22801 ctagtcggaa ttgcagcaac ttatctgccc cttctacttt ttgacagttg atgacttctg
    22861 ctacttttag ttctactttt tcaaatacat caaatttgat ttgtttttct ttcgttgaaa
    22921 caagttctgt ttcttctgga tcccatttga ctgtatcttc gtttgtttga gtaccttcag
    22981 acattttttc ttgaataaaa gcaacttctt cttccatatc taaacgtggg aagattggtg
    23041 taccttttgc aactactttt gttcctgaag gaaattcgcc aaagtgtaat ccttcaagat
    23101 tcattgtttc agagtccaat cctagttgat tgaagatctt ctctggcgtt tctgtcatga
    23161 ttggctgaag taatatcgct gcgatacgca aagattcagc taaatggatc atgacactat
    23221 tcaattcagc tttcttttct tcgtcttttg ctaataccca tggttctgtt tcatcaatgt
    23281 atttgtttgc acgagaaatc agcacccaga tttcagccaa tgctgtattg aattccattt
    23341 tttccattgc atcatggtaa cgtccgacaa cgttagcagc cgtcgtagac agttcactat
    23401 caaatggagt gacaagtgag gcatagtcag gaacgagtcc atcacaatat ttgttgatca
    23461 tagcaatcgt tcgattcaat aagttcccta gatcatttgc cagatcataa ttgacacggg
    23521 aaacaaaatc ttctggcgta aagacaccat ctgacccaaa cggaacagca cgaagcaaat
    23581 aataacggag tgcatctaaa ccataacgtt ccacaagcat ttcaggataa acgacatttc
    23641 cttttgattt agacattttt ccgtctttca tcaatagcca gccatgccca aatacttttt
    23701 taggtagagg caaatcaagg gccatcagca tgattggcca atagatcgta tgaaagcgaa
    23761 cgatttcttt accgaccatc tgaacatctg caggccagta tttttcgaat agactttcat
    23821 cttcggagcc atatcctagt gcagtaatat aattggataa tgcatcgatc catacataca
    23881 ccacatgttt cggatcactc ttgactggta ctccccaagt aaaagttgtt cgtgaaactg
    23941 caagatcctc taatcctggt ttgataaagt tgttgatcat ttcgttttta cgagattctg
    24001 gctggatgaa ttcgggatgt tcttcatagt attccaatag acggtctgcg tatttgctca
    24061 tgcggaagaa gtatgattct tcttttacca attctacttc gtgtccactt ggcgctttac
    24121 caccgatcac gttaccttcg tcatctttgt acacttctgc aagttgtgtt tctgtaaaga
    24181 attcttcgtc agaaacagag taccagcctt catattcacc taagtaaata tctccctgtt
    24241 ctaataaacg atcaaatatt ttttgaacag ctgctttatg gtaatcatct gtcgtgcgaa
    24301 tgaatttatc ataactgata tcaagcgttt tccataattt cttgacatca gccgccattt
    24361 tatctacata ttcttgcggt tttacaccta gttcttctgc ttttgtttcg attttttgac
    24421 catgttcatc cactccagtg agataaaaca catcaaagcc catcaaccgt ttataacgag
    24481 caattgcgtc acatgcaatc gtagtatacg agttgccgat atgaagtttg ccgcttggat
    24541 aatagattgg cgtagtgata taaaaagttt ccttttctgc cacggggctc ttcctccttt
    24601 atcgcatgat gcgaattcgt ttccttgcta gtataccata aaaaaagcat gctgttagct
    24661 ttttttcaaa atgaaaaaga ctggataaac gacttctatc tacgttcaat ctatccttta
    24721 aaaggatgaa taggttgaat aaatgcgggt ttttgttttg tttcatatct actaaaaaac
    24781 ggctttttat ttctcccctc acacgtggta taataaagac tatctatctt agtaagggac
    24841 tggaacaatc atgcagaaga aacatctttt ttttacactt agtattgctt ttctttcatt
    24901 agcacattta atattcagct atttttatat tcgtatgtat ggttatttta acctccatgg
    24961 gcatttgaac agttttatga cagcagcttg gattttgcgt tttatcattg acgtatatat
    25021 cgttatttgt ggcttctttg ccattcgtga agagcggtat aaagtattgc cgttttatct
    25081 gcttttcttt ttattcaatc tcatacttcc atttattttt catatttaaa tgataaccta
    25141 gatttttcaa gtaaatcctt ggtttttttt cagagtctgc tacaataagg taaaaagtac
    25201 ttttactgtc aatggaggtg gtcagatgaa ccgttttgct tctaaagaag aagaaaaatt
    25261 atattatgaa cataaagcaa gtgaagaaga atttcttaac tggtatcaaa aacaggaacg
    25321 tccagaatat gacaagccct ctttgactgt cgatatcgta ctgatgtgct ataacaaaga
    25381 agaagatcag ctgaaagttt tgttgatcca aagaaaaggg catccttatc gaaattcatg
    25441 ggcattgcct ggtggctttg tccaaaagga tgagtcaact ggagaaagcg tcttaagaga
    25501 aacaaaggaa gaaactggtg tggttatttc aaaagaaaat attgagcaac tgcatacatt
    25561 cagtacgcct aatcgagatc cgcgaggctg ggtcgtcaca gtcagctact tagcctttat
    25621 tggagaagaa ccgctaatcg ccggagatga tgccaaggaa gtacgctggt tcacactaga
    25681 acgtcatagt aacaagatcc atttatctag cggagaagtg gctatctcgc ttgatttagt
    25741 cactggagag tcttctggca aagatacttt ggcttttgac catagtcaaa tcatcttgaa
    25801 agcattcaac cgtgtagtca ataaaatgga acacgagccg caagttctac aagttttagg
    25861 taaagatttc acgattacgg aagctcgaaa agtatttgct aaattcttag ggatcgatta
    25921 taaaacgatc gatcattcca attttaagaa agctatgctc caatatttcg atgagatcgg
    25981 tgaacgtcct gtaggaatcg gccgtccttc aaaaatctat cagctcaagc cggggcacca
    26041 tgaataaggt tgtgagcaaa agattcagac ctaatcattc aagaaaaaac gcaaaaacaa
    26101 ctctttgtga gttacgtttt ttgtttcaga attttgatgt attcgtaaac tttctgaata
    26161 aaaaattaac aatagcagaa aaagctcgta cgaacttttt ctgctattgt tttattggtt
    26221 tgtcataatt agtgagcttt tcttcaaaag aaaaattcct agaaacaaaa gtcattaaga
    26281 ctttttatta acaaggctaa ccctaacgct cctatcagtt tcattcattt tttatccctt
    26341 gataaccgaa tgtctgccca ttttttctac tacttggctc tttcttacgg aattgctttc
    26401 ttctgctccg tcggtattga tcaaaagaaa ttttttatta taccattggg acttataacg
    26461 caattttgtt attaatttat gccagtcgtg aatagaaaaa tcagcatgtg cctcttcttt
    26521 tggaaaagat tctacaaata agtagtcata ttgtttgacc aatttcccag ataattgttc
    26581 aagataatct tctcgctggt tcttttgttt cagataaaga tccattactt ttctcttttg
    26641 tttctgataa ttgcttgcct gatctaacct gatctttcta tggtgagcgg agcggacttt
    26701 cacattcaat ttccgctgtg catgttgcag cttttcttct gtctggtgaa attttggtaa
    26761 agttacttct agaggtcgag atgtttggat caatgtcttc ggatgatagg cgatcccgat
    26821 ccatttagct aaagattctt tttttactgg cgaaacatca caaagtagtg cgacataaaa
    26881 ttcttcatta tatcgagcag aaatcgtagc ggagcgaatc gatccttcaa ctggccgatg
    26941 ctgatttatc ttgattagtt ctttttgttt tggtaacttt aagtagccat tttccagata
    27001 gatcgtacgg gtttggttgt tggtcgtata agattgccac atactttttt tcgttttaag
    27061 ctttgggaag ctggcacgtc ccttgaaata attgcgaaaa gcccgatcca aattaagctg
    27121 tgcatttgct aaagcaagac tgtctacttc ttttaagaat gggtattctt tttttaatgt
    27181 agcgggtgtg agcgaaaaat tggctactcc tgtttgttgc caacttttct gccgcttttt
    27241 cagcaaatgg ttataggtaa atcgagcaca tccaaaagta cgaatcaatt gctgtttttg
    27301 ttcttctgtc ggatacatac ggaatttaaa agcttttagc atctatgtcc ctcctagtta
    27361 gcaaccagaa gagattcctt ttgtcgtttt agtttttttg cgtaatatgg gacttcctgc
    27421 tcagttgcat agacaaaatg ttctggtgcg atttcacgaa gttgacgtac ttgtccgtca
    27481 tctggttcag gttgatattt gattcttctg cgttttctct catggtctgg atctggtaga
    27541 ggaatagcag ataacaaact ttctgtataa ggatgaacac cgtgattata gatttcatca
    27601 cttgttccca tctctaataa caagccgtta tgcattacac cgattcggtc actaatatgt
    27661 ttaaccatcg acaaatcatg tgcaataaat agataggtca attgatgttc tttttggaga
    27721 tcttgcaaca aattgaccac ttgggcttgg atcgacacat ctagtgcaga aattggttca
    27781 tcacaaatga taaaacgcgg ttttactgcc aatgctcgtg caataccaat acgctggcgt
    27841 tgcccacctg aaaattcatg aggataacga gtaccgtggc ttggattcaa tccaacagtt
    27901 ctcaatagat catcgacttt ttttgcacgc tcttcagatg atttagctag tccattaaca
    27961 tcaattcctt cggcaatgat atctctgact ttcatacgag gattcaacga agcgtatgga
    28021 tcttgaaaga tcatctgaac atcatgccgg aatttcgtca aacctttttt atctttgatc
    28081 ttcgttatat cttgaccgtc gaataatatc tcaccatcag taggttcatt caagcgaatg
    28141 atcgtacggc cagtagtgga ttttccgctt ccagattctc caactaaacc gaatgtttct
    28201 ccttcataaa tgtgaaagct gatgtcattt acagcatgta cttcattctt ttttcctaca
    28261 ttgaaatact gtttcaatcc tttaacttca agtagtttat ttggcatcag caattcctcc
    28321 ttgaccgtaa gtatgttttt gtttctcttt aaagatagcc cagcgacgtt ggatttcttc
    28381 tggcggtgtc actttgggtg cctgcggagc aagtagccaa gttgctgcct tgtgtgtttt
    28441 tgatagttca aaaaatggtg gttcttgttc tgcatcgatt ttcatcgcga attcatttct
    28501 tggatagaat gcgtctcctt ttggcgggtt caataaatcc ggtggagaac caggaatagc
    28561 atacaatcga tcgttcgcac tatctaatgt cggcattgaa ccaagcagtc cccaagtata
    28621 gggatgttgc gggttgtaga aaatttcttc cgatgttcca acttcaacga ttcttcctcc
    28681 atacatgaca gcgacacgat cagcgacatt cgctactaca ccaaggtcat gagtgataaa
    28741 gataattgat gtatcgattt ttgtctgaat ttctttcagc agctccaaaa tctgtgcttg
    28801 aatagtcaca tcaagcgctg ttgtaggttc atcagcaatc aggatttccg gataacatac
    28861 cagtgcaatc gcgatcacga tccgttgacg ctgacctcct gagaactgat gcggataact
    28921 gttgatacgt ttctcagctt cgggtattcc aactaattta agcaattcta atgcagcttt
    28981 ttgtccctct ttttttgaaa ctttattatg ctttctaagg gactcagcga cttgcttccc
    29041 aatgggcatc gtcggatcta aagaggtcat tggatcttgg aaaatcatcg ctatttcttt
    29101 accacggatt ttttgcatct ctctttctga ttttccaacg atatcgttac ctttaaagag
    29161 gatttgacca gcatctatat tggcgttgct tgacagcaag cgcatgatgc ttctggtcgt
    29221 cactgatttt ccacttccag attccccaac gatcgccaat gtttctcctt tattcaaatg
    29281 aaaattgaca ccgcgaatcg ctcgtacctt tccagcatac gtatcaaaag agatttctaa
    29341 gtctttcact tctaaaattt tcgtcatcgt cttcactctt tcattttagg atcaaaggca
    29401 tcacgcaatc catcagcaag taagttaaag ccaatcatga taaccgataa agttactgcc
    29461 ggaatccata atagataagg cagatacagg aatgtcttgt acccttcgct caacatcgtt
    29521 cctaatgaag ctgacggagg cgtaagacct aaaccgataa agcttaaaaa ggcttcgaag
    29581 aaaatagcag atggaatact aaacatcatt tgaataataa tgacactaga gatattcggc
    29641 aaaatatgtt tgaatgcaat tttcattctt gattcaccta atgtcaatcc agctaaaaca
    29701 tattcttgat cttttaattt cattgtttgt gcacgaacga tacgtgccat tggtatccag
    29761 tttgtgatgg ccatagcagc cacgattgaa aaaattcctg gttcaaaaac gaccaacatc
    29821 aaaatcatga caacgaggtt tggaattcct gataagattt ccaaaaaacg ttgcatcacg
    29881 ttatcgacac gtccgcctaa caaaccagaa accaacccgt aagctacacc aatcgttaca
    29941 tctagtaatg cagcaataaa tgcgatcagc aacgagattc tcattcccat aaataagcgg
    30001 cttaatacat cacgtcccaa accgtctgtt cctaaaaaga aatttacgtt tgaagggacg
    30061 tttgcttgag catatttatc aacaagttca ccaccaacca ttgcttttcc attcaatcca
    30121 tcgatattga ttcccggaat acgaggaggc aaattgatat aagccacgtt ttgggcagtt
    30181 ggatcatgag gagaaacaaa gattgtgatc acagagatca aaatgatgac caatagtaaa
    30241 accattgaaa taacggcagc tttgtttttc tttaaacggc gccatgaatc ttggataaaa
    30301 ttcaaagaag gtgcagtaat ctgttcacgt tcttcttcgg tatttttttg taatggaaga
    30361 aattcatccg cagggatatc tgcaactgtt tcataacgct ttggtatcat ttccatttat
    30421 cctcggctcc cttctgaaac acgaattctt ggatcaacta gaccgtacaa tagatccacg
    30481 atcaaaataa caaaaatcag cataaatgag taaaggatcg ttacagccat gatcgtagga
    30541 taatcatttg ttgtgattga cttaacgaat tgttccccga taccaggaat agcaaagata
    30601 ttttctacca ccagtgatcc ggtcatcaat gctacagcta acggtcctaa taaagtcatc
    30661 aatggaatca aactatttcg aagaccatgt ttaaaggcga tttcccaacg gctcaatcct
    30721 tttgcttttg ctaattccac ataatcacta tgcagtactt ccaccatttc cgtacggata
    30781 aaccgagcag agtcagcaag cggcgacatg gccaacgcaa ttgttggtaa gattgtgtac
    30841 acaaagccat cccattttgc gattggcaaa acttgtaatt tgattgcaaa gatatattgt
    30901 aataaaacag caaatacaaa gtttggaatg gaacgaccta atatcgctac gagtgtagaa
    30961 gatgtatctg cccatgtatt ttgcttcatg gcagagatcg ttcctaaaat cgtccctagg
    31021 actgttccaa agataattgc ctgtaaccct aactgcaagg atggtccgat tcttccagct
    31081 aacaaatgtg cgactggctg gtttttaaat tggaaggaaa ttccaaaatc tccttgaagc
    31141 aaattagaaa gataaatccc atattgtacg ataactggtt tatccaaacc gacttgttta
    31201 tttagcatct cgattgtttc aggactcaaa cgttcctgat tcgtatatgg cgtgcccggc
    31261 agcaattgca tcaagaaaaa ggtgattgtt gcaattaacc aaagcgtgat gatcatgaaa
    31321 aagacacgtt ttaatacata tttgatataa ctattcacta atgtttcccc ctagcttttg
    31381 acttctgaca gatgtttcgc tacattatta gataatgaac caaaaataaa ggagcaatca
    31441 aatgaaaaaa aaatctatcc cctacgcagt agcttttcta ctgattctgg ttattttaat
    31501 aaaaaatctc atcaaccatt cctttacact cattcaatta tctaatgatc tattcttatg
    31561 gtcattgccg tttctgatta tcggcggttt tttatgggtc ttttcttcgg gtttcttcga
    31621 tcattttcag cgatcggtcc atcttgcacg aacaaggaac cgaaagaaaa aaccagaatt
    31681 ttcctcgctc tcgtctgcca gctacggtat gtacagcttt tggctgatca ttgccggaat
    31741 actaattgct ctttctgcta ttttcatgct tttttctttg ttaggataag tgaatatgag
    31801 aacgaggttg cgacatttgc cgcagcctcg ttttttctca tgctcacggt attaacgatt
    31861 attcttcaac gtatgtccat ttgtaatccc atgaagcgcc tgccgcatgg tgaacgatac
    31921 ctttgatttt ttcattcact aggtgacctt ctgctttttg gtacaccgga acgacaccca
    31981 tatcatcaga gatgatcttg attgcttttt ggaaatcatc ccaacgggct tgttcatcgc
    32041 cagcgtctgt tgatgaagct gctttaactg cttcgtcata ttctgcattg ctccagcgac
    32101 cacggttgta tgaattacct gtgacaaaca aatcagtaaa gctgcttggg tctgcatagt
    32161 cagcagccca tccgcctagt actgcgtcaa aatcacccga agttgagcgg tcaagacgta
    32221 cagagaatgg aacaggtgtt ggtttgactg ttacgccatc caagttttct tggattgagt
    32281 tttgaacata ttcgattact tttttcgatg aatcatcatc agaagccatc aaatcaaatt
    32341 ctaaagaatc aacgcccaat tcttttttcg ctttttccca atattctttt gctttatctt
    32401 tgtcataaga aactaatttt ccagcttctt ttgcaaagtc ttcgttcgtt gttggacttt
    32461 ttaccatatc tgatgggatc aatcctgtag agacaactga tccgtcacct agtacttgtt
    32521 ttactaaagc ttcacgatcg atagaataag aaatagcttt tcttaggttc acattgttga
    32581 atggtgaatt cttttcacgt tgattgaatt cgatatagct tgtccgcgct tctttaacag
    32641 aagtataagc tggatcgttt gcgttttgct gtgctaactc accagacaag atcacgtcat
    32701 ctgcttggcc atctttgaat aagttcaatg cagtagaaga ttcttttact acactgactt
    32761 tgatttcaga aagttttact gtatctttgt cccagtaatg atcatttttc ttataagtcc
    32821 attctgtatc tgttcctggt ccatcaaaat cttctaatgt gaatggtcca ttataaacag
    32881 ctttatcact tgcagatgca taggcatccc cattttcttc cactacggat tgtttttgtg
    32941 ggaaaaatga tgggaaagca agcagatatt ggaaatatgg tgtttgtttc gtcaatttga
    33001 tttctaattc atagtcacca actgctttga tccctagttc tgatttatct ttctttccag
    33061 ctgtaatgtc ttctgcattt tcaactggcg catacaggta agcatattca gaagctgtag
    33121 ctgggtctac tgttcgttgc cagccataaa cgtaatccgc tgctgtaaca ggatcaccat
    33181 ttgaccattt tgcgtcttct cgtaatttga ttttgtaagt taatccgtct tcactgactt
    33241 ctgccaactc gctagctcct gccggctgtg gtttgctgtc ttcatcaaga cggtaaattc
    33301 cttcataaac gttattcaat gctgtaaaac tgattgtatc tgttgcaact gataagtcag
    33361 ctgtaggcat ttcttgaggc acgactaagt taaatacgcc tcctccatct gctgaaccgc
    33421 tttttgctga actactgctt gtggctgaac tgccgccata acatccagca agtacaaggc
    33481 cgcataccgc aaccaaacca aatgtaaatt tctttttcat tttacgtacc cctttattgg
    33541 aattttcaga ataattaata ttttctgaag ttgtttaaga gtttaatgaa taattattaa
    33601 aaaatcaaca cttttttttg tctttttcat aaaataatga ttttttcgtg aggtttcaag
    33661 gaatttttca gaaaaaatag ctttgtacaa ggttttccat ggtcttccaa aagccattaa
    33721 ataattttcg ttatattgtc tattattgcc atacaaagat aaaaaagaat aaacaaaaag
    33781 aaactgtgac aaaagtcttg tcacagtccc ttatctgaat aaacggtgtt caaaagccag
    33841 tttctcggta ttaagccaaa tttatgcaaa aatgtagaaa gccattttca caaaattttt
    33901 cttactactc gaaactaagc gactttttca caacctctgg tacacggtgt tccaaaagta
    33961 gcttcttcgg aaataagttg gaatttcaca aaaattcaag aagtaatttt cgtaaattcc
    34021 ttcttatttc ttgaagctga ttacttctgt cacaacctct ttttattatt gagaatttgg
    34081 tcgaggaata atcgtttttg ccatccaaat atccggtttg tcccagccat ttgcatttgg
    34141 taagacacct acgattttat aacctaattt ttcatagaat tcatacggat gttcacgaag
    34201 gttctggatg gaagccactt tatcaaatgt atgctcatac aggtccgttt gacttaacgt
    34261 tgttccatgg tctaaatcat ccgtacctaa ataaatcgtg attcctcctc tggaagctac
    34321 ttctttttct aagtaattga ctaatcgagt acctatttgg ttctttcgtc gggagctttc
    34381 tacaactaat ggatgcaatt cccaacctgt gataccgtat tgagggattg caccaataaa
    34441 tcctactaac tcatcttggt ctaccgctgc taccgcgatt cgttctggat tcatcatttc
    34501 ttctacttct tctgccgagc tgtctccata ttcttccggc caagtcagtc tcagtaaatc
    34561 agaaagctga tctttcaata ctggattatt acggtcaaat tcactgatta tcatacgtct
    34621 tcccccttgt tcttgcttat tctaacagtc cttttgaaaa aacgaaatgt tctcgctcaa
    34681 aaatctttag ctaccaatca gtatctctat tctttcatta tttatcttac ttataaaata
    34741 aaaaaattat acagaaacac tttattcaaa ataggaaaga tcaggaaagc catcaattgg
    34801 aggaaaaaac tctgtttgtt catcatgata tagattatct tttgctttaa aaaaaaccaa
    34861 ttatgaattg acaaataaaa cctgttttca tataataatc ttaattttta gaatttttag
    34921 ataattacaa aaaagcaaag ggaatcggta gaaatactaa gaggaacaaa aattcattat
    34981 tgtcgttttc aatgtttttg tacttgttcg tttttaggat acttattgat gatttcaagg
    35041 tgttcatgcc accttattca tcacttatcc tgtcttaggt tcacctctac tccatctaca
    35101 gccgcagtca gatcgatcac tctttaaaat tttaacccgt ttcaacgaag aaagaaggaa
    35161 atgaatatga gtcaaagtgt tttcttacca aattatacca ttggaacaga tgcgtatgaa
    35221 aaagcaaatg gaatcgtcaa agaatatggg acaaaagtag tgctgattgg agggaagact
    35281 gcactttcaa aggcagaaaa caaaataaaa gtagctttga cacaggaaat agaggttgtc
    35341 gccagtctct ggtacggggg taattcaact tatggaaata ttgaacagtt gatccagcat
    35401 gaaagtgtcc aaaaagcaga cgtcctgttt gcagtcggtg gtggccgtgc ttgcgatact
    35461 gtaaaagtca ttggtgaaaa actagctaaa ccagtcttca cctttcccac tattggttcg
    35521 aactgttcgc ccgtcactgc ggtatgtgtc atctataacg aagaaggcgt aatggacgga
    35581 ctcttctttc cttcaaaacc acctgtacac accttcattg atacagcaat tattgccgaa
    35641 gcacctgata aatacttatg ggcaggtatt ggcgatgctt tatccaaaga agtcgaatct
    35701 actttttctg ctcgtggcga tgatctaggc tacacggata gattaggaat ccaaatcgga
    35761 aaaatgtgca ttgatcgtct cttgacttat ggtacgcaag cattgaaaga tagtgccgac
    35821 gatcgtccct catatgcaat tgaacaagtc gtttcggata tcattgttac taccggattg
    35881 gtttctgttt tagttaacaa taactataat tctgctatgg cacactcatt ctattacggt
    35941 acgactgttc tagaaaaaat ggagggatac cttcacggag catctgtcag ttatggtgta
    36001 ctgaccttat tgatgatgga tcagcagttc gatttgtttg ataaaatcta tgtgtttatg
    36061 aaaaagaacc aacttccagt atcgttaacc gacatgaatc tcaatgtcac gaccgattta
    36121 gaagcaatct tagataaagc catggcaaca aatgatatta aacatgtgcc ttatgaaatc
    36181 acccgagaaa aatttaaaca ggccattctt gacgtagaaa cttatcatgc tacacaagaa
    36241 agccagcaag gatataagaa aatcagttaa ataattgcta aaacccccat caagcaggct
    36301 gtcatcaaat tgaggacatt tctttgcttg atgagggttt ttcttgtcaa aaaaagcttt
    36361 atagctttcg ctatagaatc ttttctctta tttaagttga acagttcctt aattaagaaa
    36421 actgctcctt ttatggtaat tgaaaaaacg agtaggatac gattatttgg caactgtttt
    36481 tttcatttgc ttgcttcgca attgtccgca agctgcatca atatctgtac catgttcttt
    36541 acgtatcaca cagtttacgc cgtttttctt caatacatca taaaatctca atacatcagc
    36601 ttttggactg cgagaatatt gatcatgttc actgactgga ttatatggaa tcaagttgac
    36661 atatgctaat tttttcttat cttttaatag atctgctaat tgttgcgcat gctctggtct
    36721 atcatttact tgattcaaca tgatatattc aaacgtgatt cgacggtttg ttttctctaa
    36781 atactcatcc acagcttcca tcaatttctc aattgggaaa cttcggttga tccgcatgat
    36841 cgatgttcgc acctcattat tcggcgcgtg caaggaaata gccagattga cttgcaagcc
    36901 gttattagcg aattccttga ttttgtgtgc taatccacta gtggaaactg taatgtgccg
    36961 agcaccaatt gccaatcctt tggcatcatt gatgatatgc aaaaagtcca ttacattgtc
    37021 gtaattatca aatggctcac cgatccccat tacaacgaca tgtgaaacgc gttcgccaag
    37081 attgcgctca tcaaaataat gttggaccat catgatctgt gcaacaattt ctccagcagt
    37141 cagatcacgg ttctttttga gcagcccgct tgcacaaaac gtacagccga tattacatcc
    37201 tacttgtgtc gtcacacaaa ctgacaagcc atattcttgt ctcatcagta cagtctcaat
    37261 catgttttta tcagggagtt caaacaaata ttttactgta ccatccgaag cttcttggac
    37321 gaccatctgt tttagaggat tgatgataaa atgctccgat aatttttcga tcaattgttt
    37381 cgatagattc gtcatttctg tgaaattact tacacgtttt tgatacaacc attcccaaac
    37441 ttgggcagct cggaattttt tctcgccgtt ttctataaac caattgatta attcttcatt
    37501 cgtcaagcca taaatggact gtttttccaa agtattttcc ctctttttct caaagtttcg
    37561 ctacatacta tacatgattc atttccttaa tgcaatactt cacaaataaa tcgaatagaa
    37621 ctttaatctc acaaaaacta aaaagacaag acatcatacc gtattagaaa agatggaaaa
    37681 aaaccatttt ttcttttggt atcatcatgc cttgtctttt tattggttat tcgtttttca
    37741 acccttcatc acacaagttt tacatgtcat tatcgtccgg caacgtttct gatgtttctt
    37801 cctgctcaat gaatactttc cgaggcttgc ttccttctga cgggccaaca actccatgag
    37861 cttccagttc atctactaaa cgtgctgctc ggttgtaacc gatccgaaat cttctttgga
    37921 gaagggaaat acttgccgtt tgcatttcaa cgacaagtgc ttttgcttct tcaaacagct
    37981 catcttgtgg ctgttctgga gcacctgtcg tttcaacttc atctgtcggc atcattttct
    38041 cttcataatg agcttcttgc tgatctgtaa caaattgaac gacccgttct acttcgtggt
    38101 cagaaatgaa tgctccttgc acacggatcg gtttattctc acccattggc aagaatagca
    38161 tatctcctcg ccctaagagc ttttctgccc cattagaatc aatgatcgtc cgagaatctg
    38221 taccgcttga taccgcaaat gccattctgg aaggtacatt tgctttgatg attcctgtga
    38281 taacatccac acttggacgt tgagtagcta ggatcatatg aatccccgct gcccgagcca
    38341 tttgcgctaa acgaataatc gcatcttcaa cttcattgct ggctaccatc atcaaatcag
    38401 ctaattcatc tacgatcact acgatgaatg gtaaggttgg atgtttcgtt ccgttttcca
    38461 agtttttctg ttgaacaaat tcattgtaac cagaaatatt tcttactccg gttgccgcga
    38521 atttttcata tcgttcttcc atttcttgta ctactttttg taaggcttgc gctgcttttc
    38581 tagggttcgt cacgaccggc gtcaacagat gaggtatgcc gttgtacata ttcaattcaa
    38641 ccattttcgg atcgatcatc atcagtttta cttcatgggg cttagcacgc attaatatac
    38701 ttgtgataat cccattaatt gctactgact tcccactacc agtcgaacca gccacgagta
    38761 agtgaggcat cttcgaaaga tcagccgttt gtacccgtcc agaaacatca cgtcctaaag
    38821 gtacttctag taatttatct gggtggtttg gttgtgcttc gatgatttct ctaaaggaaa
    38881 ccatactgat ctttccattt ggtacttcaa taccaatcag tgatttacct ggaatcggtg
    38941 cttccatccg gacatctttc gccgctaaag caagcgcgat atcatctgtt aagttcacaa
    39001 ttttacttac ttttacccct acagccggct ggacttcgaa ttttgtgacg gatggtccta
    39061 agctggcttt gacgaccttg gcatcgacac cgaaactttg gaaagtttgt tctaatacgc
    39121 cgatattttt ttcaattttt ttatactcat cactttgatc cacagttggt atagaatcaa
    39181 gcaaatcaac tgtcggtaat tcatagtctt gattttcctg ttctgcttca atctcaaatt
    39241 ctaatgaggt accgtcatcc tctggcaact catctgaaaa accttctgct gtattggtct
    39301 gttttggtgt atctggtact ggtttctcta gattcgcagg atggatattt tcttgaaaac
    39361 tgtcgattgg aacaaaactt agctgctccg gctctgtatt ttctggttcc tgccattcat
    39421 cagcagtatt ttccctttgc tggctcaccg cttttttctt ctcatattct gcagcttctt
    39481 tttctgcagc ttcttttgca gctaagcgcc ttgcttcttt cgcttctgcg cgctgtttca
    39541 ttctctcttc ctttgccgct tgctttcgag cttgcttggc aggatcacct tccaataatt
    39601 cctgtactcg ttctccaatt gattggatac catttaacag ctgatagcct tccagattac
    39661 tgaacaggaa tgctcctcct gccagtaata gcactgctgc taaataactt ccaggctgtg
    39721 caatcaagaa gtaagtaaaa tgataaagga ttgctccaat catcccacca ccaacgttat
    39781 tgtctacttg actttgtttt atatcactgg ctaacaaatc ccatgtcgtc cccatgatat
    39841 ttggttcccc agtatggagt ttgccaaata aatgggcatg taacaataat aagataccga
    39901 aataaaagag tatgccgcca aaccagcgtc ggtttttacc aattgaaaac tctgtattct
    39961 taatgacaat ccaaaatcct aatacggcta ataaaagaca gaggatttgg taagtatttc
    40021 ctgcaatgat ccgaaagccg tttgcaatca atattcctaa aaaacctaat tttaaaaagc
    40081 cgaagacagc aaataaaatc aaggcaaacc caacaccaat cgtcagcatt tgttcctgct
    40141 gctgtttttg ctttttcgtt tttttcgtct ttttcctttt tttagtaggc cgtttctttt
    40201 gtgccattta ttatccctca tttcatcaag tttcattata caaaaaaaag taagggaact
    40261 aaagttttgt ttgaaagaac tgacgctttc tttcattttt cagcttattt tacagttttt
    40321 cttaatttct aaatgatttt atcaagaaaa ggcacggcca tatccagccg taccttcttg
    40381 ttttaagtat gtgaactaaa ggttctctcc attttcttca atcagttttt ggtaccagta
    40441 ataactgtct ttcttatatc gttccaaaga tccttcttgt gtttcgtctt gatcaacata
    40501 tacaaatcca tatcgctttt gataaccgtt cagccagcta agcaaatctg tataagacca
    40561 ggtgcaatag cctaggactt ctgctccatc cgaaattgct tctttgatgg ctttgacgtg
    40621 gctttgtaag taattgattc gatagtcgtc atggatttgt ttatcttctg tcaacttgtc
    40681 atactctcct aagccatttt ccgtaatcag taccggcatg cggtaacggc ttgtgatacg
    40741 acgcagtccg atccttaatc cttctgggtc aatctcccag tcccaatttg ttcgttcgac
    40801 aaatggattc tcaacttttt tatacattcc aggaactcca gtttcttctg atgaaccttt
    40861 ttttcctgtc gtattcattt ttccagcacc aactccgttt aatggattga atgcattcgt
    40921 cgccgtttga tagtaattga tcccaagaaa atctggttta gcagattcta gcaattctgc
    40981 atcgccagct tcaatcgttg gtgcccatcc tttttcttct aagaacctca tggcagcaat
    41041 cggatatttt ccccacatat agacatccat ccaataattg gccatcaggt cttctgcatt
    41101 ttcagcagcc agaacatttt caggattact gtcaattgga taatttggcg tatacgcaaa
    41161 gcttggtccg atttttccag gcatttctaa ctcgtgaaat ttattgatga cagatgcatt
    41221 tgctaaatta gcaatatggt taacttcata cattcgtttc gggtctgtca cacctggcgg
    41281 atgtgctgct aacaaataac ctaatgaagt gaagatattt tgttcattca aactaatcca
    41341 gtaatggact ttcccgcgga atgcctcaaa taatgtttct gcataatgag tgaaatcttc
    41401 aatgatctga cgtgattccc aaccattata ttcatcttgc aatgcttgtg gaagatccca
    41461 atgatataaa gtcaacatag gttcaatatc gttttcaatc aattcgtcga tcaatctctc
    41521 ataaaaagcg agcccagctt gattgacttc tcctcgtcca ttaggaaaaa tccgtgtcca
    41581 agctacagag aagcggtaag ctttcagacc ttgttctttc attaaagcaa tatcttcttt
    41641 ataacgatga tagtggtcta ctgccaaatc accgttcgtt cctttaaatg tctttccagg
    41701 tatccgtaca aatcgatccc agactgattc tcctttccca tcttcttgcc aagctccttc
    41761 tacttgatac gctgcagaag cagagcccca cagaaaatct tttggaaatg aggtaagttc
    41821 tttgtgttcc attcatctct tcctttccta taaccttcaa tcgttcctct tttagaataa
    41881 cacgaaaccc cttccacaac aaaataaaat tatgtaaagg aggttgtgaa aaagtcgctt
    41941 agtttcgagt agtaagaaaa attttgtgaa aatggctttc tacatttttg cataaatttg
    42001 gcttaatacc gaaaaactgg cttttgaaca ccgtttacca agaggttgtg agcctgccat
    42061 tcagctccga gtcacaagga gttggcagga gaacactgtt tattcggaaa aagggactgt
    42121 gacacgtctt ttgtcacagt cccctatttg ttaatttctc ggcgtaacat cttcgccaaa
    42181 ccatttatcg gatatttttt ggaattcacc tgttttctct agttgatcta gggcttcatt
    42241 gatttttttc actaatgtac tatctgactt gcgtgcacca actgcaaaat cctcactctc
    42301 ataagaacct tttgttatgt tgaagtcttc tagttcgttt ctttgtttca aataatagtc
    42361 tgcgtatact ttatccatca gcagaccatc gacccgtctg cttttcagat cgatcaatgc
    42421 ttcattaaaa ctatcataca aaacagcatc ttggtttttg actatctctt ttaatacttc
    42481 tggttgtttc gtaaatacat cataaccaga tgacccattt tgcgcaccta atctcttatt
    42541 attcatttgt ccaaagtttg tgattcctga ttctttaggt gtgatcagca cttgatcgtt
    42601 ttccatataa ggttttgtaa attgcacttt cttttctctt gccggcgttt tggaatagcc
    42661 gttccatatc aaatcgatcg ttccattgtt cagttcaaat tccttcattg accagtcaat
    42721 gggctgaaag tctaccgtaa tcccatattg ttcaaagact gctttggcta aatcaatatc
    42781 aaatcctgtg agcttcccgt ctttatctct aaatcccata ggaacaaatg tatcgtctaa
    42841 acctataacg atttttttct cttcgttgat agtcgcccaa ttatctgctg aagttttttt
    42901 gttcgaacag cctgcaaaaa gaagaagacc tgcgatcaaa gcgaatagaa aactggtttt
    42961 tttcatctct atcttctcct ttcttaatga attggggaaa cttttagtaa ttgatcaccg
    43021 acattttctg caaatactaa atcatgggtg acaataattt gggttacccc atcttctttc
    43081 aatgatagga tcaaacgctc gacttgctgg cgtaattcag gatctaaagc acttgttggt
    43141 tcatcataag ccaatacccg tggattcata gccaatgctc tggcaatcgc tacccgctgt
    43201 ttttgtccgc cagaaagctg ataaggatag atattcaata aatcactaat ccctaatgaa
    43261 gccgctaatt cttctgcttt tttggtgtat tcttcttttg tctgtttcaa taccattttt
    43321 ggtgctaagg taatgttttc aaaaatattc agatgtggaa atagctggaa gtcttggaat
    43381 acgactccta caacttgttc tttcatttta agctcgaatg ggttgaacgg tacaccgtct
    43441 aaataaaatt ctccgctgtc agaactttct aagccagcca agatacgtaa aagcgtggtt
    43501 ttaccgccac cggaaggacc tacgatagct aatgttttcc catctggaat gattagattc
    43561 aaatctttga ttattttttt ttcaccaaat gctttgttca ctttcttcaa ttcaatcata
    43621 tttcttcctc ctatcagtta gcggtaataa tttaattttc cttcaacttg tttcattatg
    43681 attgttagaa taccagtcaa tgtaagatag atgattgcca cgcctagcaa aggcagtaaa
    43741 gtcgcgtcgc gttccatcgc gattttccca gcacgcatta cgtcacctaa acctaatata
    43801 tagatcaagg aagaatcttt gaccaagttg ataacttcat tccctacaga aggtaaaaca
    43861 atctttgtca cttgtgggat gacgattttc gtcaccgttt gaaagggact taattgcaaa
    43921 acttgcgctg cttcatattg accttgagga atcgattgta tccctccacg aaagatctct
    43981 gcaaaataag ctgcatagtt taagataaag gcaatgagtg ctgcttcgaa acgatcaaaa
    44041 acgatcccaa tcgtcggcaa cccataaaaa ataaaaatca gttgcaacaa cagcggtgtt
    44101 ccccgcataa cccatacata tgtttgaagc aagtagcgta gcggcttaaa atgcaaagac
    44161 aatcctaatg ctaaaacaat ccctaatggt aatgagccaa tcaaggtaaa taaaaataat
    44221 ttcaatgttg tgagtgctcc tactaataat tgcggcataa cttcaatcaa atactccatc
    44281 ttcttttcct cctttaaaat aaaaaaatcc tcttggcaaa tgccaagagg acgtattata
    44341 cgtggttcca cctctgttta ttttttcctt gcagaaaaaa cctcacacag tcgttgccgt
    44401 tcagatgaaa acaaaaagtc ctttgatccg aagatcaaag gacgttaatc acgtggttcc
    44461 accttttttt accgactcct cacggaaaag ccagccttat ctggtcatct agcaacgacc
    44521 gcagctgtaa cgggctcccc ggattttcct actatacgct tcagaaaatc gactccaaga
    44581 tgtgtttcac ggttaactgc tgcctctttc caccaaccag agactctcta aaaacaccta
    44641 acggctactc ttcttttcga tgtcatttgt tttaacttta cgtgtaattt acatgattat
    44701 ttttcatttg tcaactcttt tttatgatac actaataaaa aaaggagggt gatgcgcgat
    44761 gagtcgtgca accgaacaag aagcttatga actactaaaa aaactgggta tctcttttca
    44821 aaaagtcgat catcctgcga ttacgtcagt caaaaatgtc cctttttccc tacctggtcc
    44881 gcaagtaaaa aatctattat tgaaatcaag aaaaggaaaa caaatctatc ttgtcatctt
    44941 gcctgatgaa aagcacgccg atttaaaaca actagctgaa caattaaaag aaaagcgctt
    45001 atcttttgtt tctgaagaac agcttcctga cctcctaggc gttccagcag gtacagtgac
    45061 tccattagca ttgatgcacg acaaagagaa aaaaatccaa gtcgtgatcg atgctgctat
    45121 tgatcgtcaa gataccgtag gctttcatcc aaatatcaat accactacgt tgattatgga
    45181 tttttccgac tttgaaaaga tacttgttta cttagaacat ctgccagttt atgaaaattt
    45241 gtaatgatag agtagttttc ttatttccca attcaagcgt ctttttcttt atttagcaca
    45301 aaatatatca gaaattcttt tggccaatca aacaatgtaa caactagtat gaacgctgaa
    45361 aactaatacg agtattcttc catagttagc caaatccata tttattgatt ctacgaaaaa
    45421 agaagcatat ataaaaatgc ttcttttttc gattataaat cggaatttta ttcttttgat
    45481 ttcagtcata tttaacaaaa aatattatat tctaactaaa cttttttata tttttgtaag
    45541 aatatcccag cacagatagt tactatcaat aaaccaatga ttacagcaaa actagatttt
    45601 ttactacttg ttttaggaag aatgcttttt gatttatttg ttatctgttt aggtacagct
    45661 ctcttactaa tataattgct tctttgttcg ctggattctc ctgtatgagc aaatatttgc
    45721 aatttttgag agaatagatt tctaattttc tctctctctg tcttctctgg aaaatttttc
    45781 cacggtgtta tatggctacc tggtatagat atatttgttt tttccggtgt ataactgttt
    45841 ttgatgttat acccgtcaat cgtcgtactg tattcgggca cgttgtcttc cgttacagta
    45901 tagatgattt cttgcccgtc tctgtatttt ggcagatttg tgaaacgata gcgccaatca
    45961 tctttttcac ttacttcttt gtgttggatc ggttgaccgt cggctaatag atttactgtg
    46021 atcgtcgtcg gtcgtttgcc gtcttggttc tcattgtctt cccatgtttt ttgtcctgag
    46081 actgaaatga cttctttatt ctcatttgta acgactagcc cgttttcaat tttttgataa
    46141 cctgaaggga cataatcatt tccgttttga tctacttctt gcactttaaa cgtatattcg
    46201 tttccactat catcatactg ttggatatct tcccaagtca ctgaagttat tccattgtct
    46261 aatcgttttg tttctgcatc aggaactggt tcccaattgt ttgtacttgc tctgaataat
    46321 ttaaaataaa tactcggtct tggagtggtt ccaccgttcc aaattttagt tgctgtgatg
    46381 ttcgtaacct ttttcttgtt ataaataggt aaactgactc cctctgtatc attttcgttt
    46441 atggagaatt tgagttcatt tgaacttagt ggatcaaaat caatccaatt gggtgcttct
    46501 ttttctttta caacatagtc tcctacttgc aggcctttga tactagcttc tccctgttca
    46561 ttcgaagtca acaggatact agactgtcct tgaataggct gttcatctgc tcgtcttaat
    46621 tcgaaagtca catttgggat accaatctct gtgtcattga tatatttgaa aatcttcaat
    46681 tcgcctctaa ctgtaccgtt gactccacca gaagctgaaa tatttttaac tgtatgattg
    46741 aaactttctc catcaacagc aggtttatta aattctttaa accaagcttc cgaatgattc
    46801 tcaaaattta tttgttctgg gttttctatg atcgtcttat aactcaccat tattttccta
    46861 agattgacaa agttttttgg tatagttatt tcaatgtaat tatcagttac tgaaaaatta
    46921 aatgtagcgc tggggaaatc ttgtaaaaat tgttggattc cctcttctcc tctataaacc
    46981 ttctgttcac ctaagtgtat ttgattaatt tcaaacgtac ttggatctaa tctttgtcca
    47041 ctttggattt catcactgat tttaactggt tgttcaacat aagtgccgtt attgttaata
    47101 ttcaaaaacc atcgaatgtg cttagtatct tcaggtagca tgtctcctgt tttataataa
    47161 aaaacgctag aagaagaacc agaagctggc tttgtcacat ttacagtagc tgttttatca
    47221 ccgctcgtca cggtgaatgg tcccgtattt tcttcaccgg tatcggttac gtttctggcc
    47281 tgtatctcaa attgccccca accttctact gagtctaggt ttttaatatt ttcattaaac
    47341 acaacctgcg cagaatcttt tctgaccgtt aaagttccaa catttttatt ttcaatcatt
    47401 aatgggattt ctttttggaa tccttcaccg cgaatatttc cttcacttgg ccaattgatc
    47461 caaagataat cacctggttg gatattttgt tttttttcgt caaacgagaa ttttactttt
    47521 atgtttcctc catctgtaat attcgttggg tccacggtca acgaagtgac attactgctg
    47581 atatctctgc ctgcatccgc atagacatga acaggaatca gtgatgttat attagtaata
    47641 ataaataaca ttgataaaat aatatttcta cactttttca ttttttctat ctcccctatt
    47701 ttaactaaaa ataaaaccta ctatatcatc tctcaaaaat cctttcttca attcctcccc
    47761 cactcatttc caatctttta actaaaaaat tgatagttat tttacaaata tttataaaaa
    47821 ataaatatgc caaaaaactg tttttacaag gtttttccta atgtaaatta ttttttcgca
    47881 tatattcatt ttattttact tattgctttc attttttcaa tctatatttc caatttttaa
    47941 cttacaaaaa tgcaacatta ataaataacg atagtttcat aaaatacact tttaattaac
    48001 attattagtt tatactagct gtttttgtgt taattaaagg ataaaataca atataaagaa
    48061 acatctgttt ctttatttag aataaaaaaa tacagactct gttcaaataa atgaacctag
    48121 cctgcattat gagattgact atacttttta attcattgag atgaataact cgtttttata
    48181 aatgcccaaa agtaatcggt gccgaagcca ttcctcgacc taattctttt tcaaattttc
    48241 ctattgttga tatctccata taaaacggtg atactggttt agacaattct cccctgattg
    48301 ctaacggacg taaactacgt tccaaattat ttatgacttt aggataatac tgaccttttt
    48361 ctaagcctgt ctttgcgtct atcaaaagta tacgttcctt ttctttgatc tctggattta
    48421 aaacgagatc atataatttt agtaccatgt tttctatttc ttcactttta gacatcacga
    48481 tttcctccca aaaatatatt tcttcccact acattctata aacaaagtat acgctacatc
    48541 tagatttttt taaatcatta ctggattgtt aaaacctttc aatacactgt tatggcaacg
    48601 atttttattt taaaaacatt ctaaattaaa tcagtaaaaa tttttattct aagattttta
    48661 ttagaattac gcctaatttg tgtctctcag ggcaattcta agaacgtttc aagagatagc
    48721 gacactatcg ttatcgaaaa aggcgaaaac ctatctcatt ttctgctaat gtaagttggt
    48781 ttagcttttg ttaatatgac tttatgaaaa tggaggtaat taaatatgat ttttcctaaa
    48841 gttaatgaag caagcttgaa taaaggatcc ttttttcata tctatgaaaa cgaagatttt
    48901 gaactgtata atatcctttc acaaaaagag gtcatcgaaa accaaataat ctgccatcca
    48961 attatttaca aatctatttt caagtatgca ttttttgctt ccaatgattt tcaaagaatg
    49021 gagattaccg actgtatatt cgaaaactgt gatttttcag gctgtatatt gacaaaaagc
    49081 atgttgcatc gcgtgaaatt tgtcaattgt aaattaacag gtactaaatt gatggaaagt
    49141 tatattggga acacgttatt cgagaattgt aaaatggact atgtaaattt atctggttca
    49201 aacataaaag aaagtacctt tgagcactct gtcttatcaa gcgcagattt tgtagactgt
    49261 tccctcacta aaataatgtt ttctactaat gatttagaaa atgctagctt ttttgatact
    49321 gatttaaaaa atatcgattt aagtagcaac tcctttgaaa tgattgaagt acgctcggaa
    49381 catctaaaaa attgtacgct taatcagttg caagcacttg gttttgctag aaaattttta
    49441 caaataaaag tagtataatc aaaatgaata tataagataa atttttagca atacaaatat
    49501 ccataaaaaa acattgccta ttttaactct tcatgtatac tgactctatc ttcaaaaact
    49561 gaatagtagg agttattatc atgaataaca ttttaggaaa aaaaatagaa cttaaaaaag
    49621 ggatattggg cactattgtc gttgtactcg gtttgttagg gttgctattt gcgccatcca
    49681 ttattagcat tttttcttta actatcactg gatttatagc atttacactt gtttttggta
    49741 aaaaagatac gaaaaaaatg ttctcgaaac ctgtcgctcc tgtcaaaaat atagccaaat
    49801 atttttttat caatgtagta atcagtgccg cagtctcggt atttttgcaa caaattttga
    49861 aatggggttt aacaggcaat ccaataaatg aggctttcag cccgttatta tttattattt
    49921 tgcctatcat gatacttgga gaagaattgt tctcagtgta ttttctcgct attttttcta
    49981 gtaagttcag cattcctgtc gctagtttct tgtcagcaat catctttgga tttatccatt
    50041 acagtactta tgataatgga aatattttac acactgtagc acacatcctt ttgatacaag
    50101 gggtggcaag attgttattc aaccaagctg ccattaaaag caactcgatc attacaagtt
    50161 gggcagttca tgtgatattt gatttcacag ctatattgct agtcgtttta ttctcctaaa
    50221 tttttataga aataatacat gctctattgc taagaaagca tactttattt cctttaaaca
    50281 aaaagacaga tgtatcaatg gattaaaaat ccttgatata tctgtcttct cttttaatgc
    50341 cagctatagg gatcgaacct acgacctacg cgttacgagt gcgttgctct accaactgag
    50401 ctaagctggc cttatccaaa agaaattata tactctattt ggctgattgt aaagagtccg
    50461 atggaaaatt agtttaattt catgatattt ttcataaaac gtggtataat tgatgtgaaa
    50521 ggcaggtttt atgaaaatgg caacttttgg aaaatttgat acaactatcg taccatcgga
    50581 aattggtgaa aaattcaaga tcaatactca cgtaatgttc acaattcacg gcaagtcgca
    50641 aactggaacg atttcaaagc aattgaaaaa ttccgctgtt gttgagattg atgaaactgc
    50701 agaaaatgcg aacttgatga cgcaaagtaa gggtgtagta atcgttaact acaaagaact
    50761 aaaaaagatt tgaatttgac catctctgca tttttgggat ggttttttta tatgcaaacg
    50821 aaagctgtga aaaagctgtt ctgcatcaaa cgttaaaaat gaccaaaaaa ggatgtgaca
    50881 aaagttgtgt cacacccttt ttcgtattta cttattttgt accaaacaaa cggtcacccg
    50941 catcccctag tccaggaacg atataaccat gttcattcaa tttttcatct agagaagctg
    51001 tatagatgtc aatatcagga tgcgcttctt gcaaagcttt tactccctca ggtgctgcta
    51061 ccaaacaaac aaatttaatg ttcgacgcgc cacgttcttt caatgcatcg attgccatga
    51121 ttgctgatcc gcctgttgcc aacattggat ctactacaaa caactgacgt gcatcaatgt
    51181 cttctggaag tttgacgaaa tattcatgtg gttccaatgt ttcttcatct cgataaagac
    51241 cgatatgtcc cactttagca gctggaatca attccaagat accgtcaacc attccaatac
    51301 ctgcgcgcaa gattggaata atcgctactt ttttaccaga caacgttttt tgtgttgttt
    51361 cagtgatcgg tgtttcgatc acgatgtctt ccaatggcat atcccgtgat acttcatatg
    51421 ccatcaacat agcgatttca tcgactactt cacgaaaaac ctttgttccg cagtttttgt
    51481 cccgaataat agttagtttg tgttgaatca atggatgatc gatcacttga aatttgccca
    51541 ttttttaagc tctcctttgt tctgtcgttt ctttttaatt gtaaaacaaa atcaagtgat
    51601 tgactagtca aactcgccat ttttcctaag aaaatccgtt tttgaaaaga agttttcctg
    51661 cggacaagca aagcttattc ttttttcttg atccaagaag tagataatgc cattgctgca
    51721 cgcgttgcct ttgtctgatc catagcattt accatgacaa aatcatggat gattccttgg
    51781 aagcgtactt gtgtaacagg aacccctgca tcacgaagtt tgcgcgcata agcctcacct
    51841 tcatctctta atacatccgc ttctcccgtt aaaatcattg ctgaaggaag atcatttagt
    51901 tcatttatat ttgctctcaa aggcgaagct gtgatttcag cacgctcttc ttcattcgtc
    51961 gtatattggt cccaaaacca catcattcct tctcttgtca aaaaatagtt ttctccgaat
    52021 tcatgatagg aatctgtatc aaaatcagcg tttgtgactg gataatacag caattgcttg
    52081 gatattggga ggccctttcg ttcttttgtt aagatcgtca tgactgtagc catgttacca
    52141 cctactgaat ctcctgcaac gattagattc tcgagatcca gattttttga cttggctaat
    52201 ttattcagct gttgcaacac agcataattt tgttcaattg ctgttggata ttttgcttct
    52261 ggtgatcgac tatattctgg aaagacaacg acggaattcg tacgaaccgc aagttctctg
    52321 atcaatttat catgggtttg agcactgcca aaaacccagc ctgctccatg aatataaaaa
    52381 ataactggta atttatccat attcccttct ggtcgtacga gacgaatatt gagttttccc
    52441 cattcgccag tatccaccat caagtcttca atatcgacgg aatatttgtt cacaggtgat
    52501 tcttgtactt cttctagtaa aactcttcct tcttccggtg ctagttcata gatacgcgga
    52561 tgaggcgcat ttgcatcact gaatgctact gcttcctttt ctaacgagat acgatcagtc
    52621 atgacttttc ctccctgaga tttagtgtga agactaaaat tacacctcat atactagaga
    52681 gcatcaccga tattgtcaaa gaatccgttt tcccaaaaaa taaacagaaa agcccaacat
    52741 tgaacttttc tgtttactaa tggaatttaa atttttattt tttatgcaac ggaaattttt
    52801 cagttaattc gcgtacacct gttttgactt cgtctagttg agcgttatca tcttttgctt
    52861 gtaatgcttt gacaactagt tcagccactt ttacagcatc ttcttctttg aacccgcgag
    52921 tagtgattgc tggcgtgccg attcgaatac cgcttgtttt gaatggactt agtgtttcaa
    52981 aaggaatcga gtttttattt acagtgatat tcacactgtc caaaatgctc tctgcttctt
    53041 ttccatttat acctaactcg cgaacatcga tcaacatcag atgattatct gtcgcccctg
    53101 aaatgactct ggttccaatt gcttgattga aaactttgac cattgctttt gcattggcga
    53161 tgatttgttc actatattct ttaaatgcag gatctaatgc ttctttgaat gctactgctt
    53221 tacccgcaat cacatgctct agagggccgc cttgaatacc aggaaatacc gcactattta
    53281 ttttttttgc taatgcttca tcgtttgtca aaatcatgcc gcctcgaggg ccacgcaatg
    53341 ttttatgagt ggtagtcgtt gtgatatctg cataaggaac tggattagga tgaagtcctg
    53401 ctgctactaa tcctgcgata tgtgccatat ctaccatcag ttttgcgcct acttcatctg
    53461 cgatttctct gaatttcgca aagtcgatcg ttcgtccgta agcactggca cctgctacga
    53521 tcaattttgg ttgatgtttt ctagctaaaa tacgtaccac attataatca ataacttctg
    53581 ttgtcggatc aacaccgtaa gcaacaaagt gataggtttt gccactgaag ttgactggtg
    53641 atccatgtgt tagatgtccg cctgcggaaa gatccattcc taagatcgtg tcccctggtt
    53701 ctaccaaagc gagataagca gccgtgttgg cttgagagcc ggagtgaggc tggacgttcg
    53761 caaatttcgc tccgaataat tcttttgcac ggtcaatcgc taaattttca acgatatcga
    53821 caaattcaca cccaccataa tagcgatgcc ctggataacc ttctgcgtat ttatttgtca
    53881 agatacttcc ttgtgcagcc atcactgctt cggagacaaa gttttcagag gcaatcagct
    53941 ccaaattatg ttcttgtctt tcttcttctt tggcgatcgc agcccaaaga tcagggtcaa
    54001 acgttttgta atctaccaca aacaacagct cctttttatt ttcctacaat tttatttttc
    54061 ccatcaaaaa caaattgcca aatattcgta tctcttctat tacgattagt tacgcttagt
    54121 ttttcgttca ctgatagaag atttacttga tagcattgta tcatactaaa agaatgcgac
    54181 aataaccaat tgatcatttt tcaaaataat tttgtcctgc tgcttttttc aagcgattca
    54241 tgtaagcatt ccccaatcca gtttctggat acacttgtac aaaaatcaaa tctaatccaa
    54301 gtgttggttc atctaatcct cttagacctg caaacaatcc tttagccgcc gcttctactg
    54361 agttgtcgtt atacatataa acagctgcag tatctgtccg cacttgatcc gcaatttcgg
    54421 ggcttgctat gacacctgca cggatcttct tattttttgc ccattgaact gcagttgacc
    54481 aatcgccatc tctgaccatc agaacacgtg tatcgggtga gtagtgtttg tatttcatcc
    54541 caggggcttt tggtgtttca ttttctttta caagatgctg atcaatagca acaggagatt
    54601 cgatgactgc ttcgatttgt tctttcgtta ctgcacctgg tcgtaaaatc ataggcatgg
    54661 ctgttggatc acttaaatca agaacagtgg attctacacc aattcgcgta gctccatcat
    54721 caataatccc ggtaattttt ccttgtagat catgatatac atgatctgca gtcgttggac
    54781 ttggttttcc cgacgtattt gcacttggac cgacaagcgg aacaccggaa agttcgatta
    54841 cttctagtgt ttttttgtta tccggtatac gaaatgcagc tgtggataat cctcccgtca
    54901 caactgaggg caaagtgtct tttttgatct taaatatcaa agttaatggt ccaggccaga
    54961 agttcttcac aatcttctct gctgccggat gaaagttgtc cacatactct tttacttgtt
    55021 caaaagaggc gacatggacg attaatggat tatcttgcgg tctccctttt acagaaaaca
    55081 ctttcttgac agcgtttggt aaaagagcgt tggcgcccaa tccgtatact gtttcggtag
    55141 gaaaagcaac aagttctcct tctttcagtg cttcggctgc ctcttgcaat tctgtttcat
    55201 catatcgttt cgtttccaca gtttatccac aacccctttt tcatacattc ttattttgtc
    55261 tgagtttatc ctcaagtttt ccactgtttg tggataatct atttgtcaat agtggataaa
    55321 cttgttgata aaccaaaaag tcgtttacat ccttgtcaaa taagtgtttt tttataataa
    55381 aaaaacaaat aaaaaatttt tcatccacaa cttcaaccat aaacttggat cattcgttca
    55441 ttgccaaaaa gatccttttt tatcgccact tttttatctg gaaatgcttg ctgaaatatt
    55501 ttttttactg cttcaccttg gcgaaatccg atttctaaaa aaatctttcc atttgatttt
    55561 agtacgcttg gtgcttcaac tgctattttt tcataaatag ctaatccatc gttctcagca
    55621 aaaagggcca ttttaggttc gaatgaccgg acactttcat ccatcagttc ccattcattc
    55681 cgactgatgt acggcggatt agaaataatc acatcaaatt gctgatccat tactggtcct
    55741 aatgtatctc catgataaaa actgattttc gttccttctt tctgagcatt ttctttcgct
    55801 acttctaatg cttcttctga aagatccaca gcagatatat gccaattttt tcttgctgct
    55861 ttcaaactaa tagcaattgc tccagtccct gtcccaatat ctatcacttc taacggtaca
    55921 ccaggcgtct cgtctaaaca ccattcgact aactcctctg tttctggtcg agggatcagt
    55981 gttgcttcag ttacctttaa ccgatgatca taaaaatctg catatcctag caaatactga
    56041 ggtggatgat ctgcaagcag aagtcgcaga tcggtttcga tcaaccgctg ttcttcttct
    56101 gaaatctctt cgttcatatg aaggagccaa tcaagttttt tccattgttt tcgttccaaa
    56161 aataaaaatt ggatactata tgcttctttc ccatgatcct ctaaaaaaga agaagcccgt
    56221 gacaggactt ctcgataggt cattttaccc attttgcata gcttccagtt ttgatgtttg
    56281 atcatacatg atcaatgcat caacgatctc atctaatttc cctgctaaaa tctgatctaa
    56341 tttttggata gttaatccga tacgatgatc agtcacacga ttttgcggga aattatacgt
    56401 ccggatccgt tctgaacgat ccccagttcc gactgctgat tttcgattgg catcatactc
    56461 gctttgtgct tcttgctgga tcttatcgta cacacgagca cgcaagattt tcattgcttt
    56521 ttcacggttc ttgatttgag aacgttcatc ttgcatagca acaacgatcc ctgttggtaa
    56581 gtgagtcaaa cgtacagcag atgctgtttt attgacgtgc tgtccgccag cacctgaagc
    56641 atgatagata tctgtacgga tatctttgtc ttcaatatcg atctctactt cttcagcttc
    56701 tggcatcacg acaactgttg cggtggaagt atggatacgc ccttgcgatt cagttgaagg
    56761 aacacgctgg acgcggtgcg caccactttc atattttaat ttcgaatata cgttgtctcc
    56821 ggtgatcatc atgatcactt ctttatatcc accgattccg gtaacgttag cttccatcac
    56881 ttctgttttc cagccttgtg cttcagcata cttttggtac atattgaaaa gatcgccagc
    56941 gaataatgct gcttcgtctc cgcctgctgc tccacggatt tccatgatga tatttttatc
    57001 gtcatttgga tcttttggta aaagcaagat cttgattttt tcttctaaga cttctttttc
    57061 tttttttaat tcagataatt cttcttttgc tagttcagcc atttcatcat ccagtttttc
    57121 accaagcagt tcttctgtat cggtgattcc ttgtactact tctttataac gacgataaac
    57181 ttcgactgtt tcgcgcgtgt ttgcttcttc ttttgaaagc tgcataaaac gctttgtatc
    57241 agaaatcact tctgggtcac ttaaaagttc tccaagctct tcataacggt cttcaattgc
    57301 ttgtaattga tcgtacatgc ttattctcct tctgtaatca ttgatgggtg aaagtaatgt
    57361 tttcgacaaa cggggtaata agcttcattt ccgccaattt gcacttgatc gccttcataa
    57421 acagggtttc catcaatata atgtaaattc atgattgctt ttttgtggca gaaccaacag
    57481 attgttttca tttcttcgat tttgtctgca taaagcaata aatattttga tccttcaaat
    57541 aactcgtttc gaaaatcatt tttcaaacca aatgccataa ccggaatatc caattcgtcc
    57601 acaattctcg taaaagcaat gacatgtttc ttttttaaga attgcgcttc atcgatcagc
    57661 acacaatagg gtttgctttc cattttctga attacgtcaa atacgtctgt ttcttcaaat
    57721 atcggcatcg cattacgttt cagtccgatt cggcttgaaa caacgcctaa accatctctt
    57781 gtatcaatac cgcttgtcat taagacaact ggcttatttt gttcttcata attatgtgcg
    57841 acttttagga tctcgatcgt cttgccgcta ttcattgcgc catacttaaa aaatagttgt
    57901 gccatgctct ttttcacctt ccagtttgtt cctatggtat tatacttgat tttcagcatt
    57961 ttttacagtg agaattttca tcaagcacag attagtatta aatctattgc tcacttttgt
    58021 tccaattttt tgacaagaac taaacatggg ttccattcat cccataaatt tggaaaaact
    58081 tccaaccttg aaaatcctaa tgattcgtag aaacaaatag tttgatcata tatagagtag
    58141 tgcccctcgt ctacagtctt cacttgcaaa tatttgtaat gttttgctgc gtaaccttct
    58201 gcttctttaa aaagttttgt tcctaatcct tggtgatgat agtctttttt tattcccata
    58261 caatagaata gatttcggca gtatcttcac ttgtctgtga aagagtgata aagcctaaat
    58321 attcttcttt tcttttttca caccataaag gtagtttact tgattcctcg atatattttt
    58381 ccgttgattc aggaagccca aaccactcag gcaagtctag taatatttct cggacacact
    58441 ttcctttttc ctctctatct tttacaaacg atatcggcat attctttcta gattctccct
    58501 ttttgaattg agtatagcat gctttctttc ttttcacgtg ctataataag ttaaaatttc
    58561 aaagttttac gtaaggagct atttgatgac aaaaaatatt tttgattcca tcgctaacca
    58621 ttatgattcc cctgaccgtc aagcattagc caagattatt cgcgaagaac taactactta
    58681 tctaccgcgc gacagccacc aaaaagtcct gctggattac ggaggcggaa ctgggcttgt
    58741 tagtttaccg cttgcggaaa gattcaaaga actgatcatt gccgatgctt cagaaactat
    58801 gctgaaaatg gcagaagaaa agatccaagc agcagatctg aaaaatgtcc gaacgatcca
    58861 cgctgatgct tctgtcgaat ttcctgctgt ccaagctaat ctcatccttc tatcacttgt
    58921 acttttacac attcctgata cggagaatat tcttacaaaa ctttatgaaa ttttagctcc
    58981 tggcggtcaa ttgatcatcg tagactttga caagaatgaa caaattagtc atccgaaagt
    59041 ccataatggc tttagccaag aagaattgaa taatcgattg gaaaaaacgg gctttgtctc
    59101 tgctactagt cataccttcc atcgtgggga aaagctattt atgaacaaaa acgcttcgct
    59161 tttcttatcc atcagccaaa aagcttaaaa tgagattgca aaaaaagtga gcaactccaa
    59221 gaaataagaa ggaattttcg gaaaaagaag ctgtgacaaa aaacatgtca cagcttcttt
    59281 ttattttttc atcacatgat tttaatttct gaaagaggcc aataacggaa aacaactttt
    59341 ccttggatca tatctttgtc gactaaccca aacattcggc tgtcttttga aatcaagcgg
    59401 ttatcgccta gaacaagata ctttcctttt ggcacagtat attcaaagtc actcgtaaag
    59461 gtggatgaac tttctgcttg tgcttggaat cctgagctat aagcatattc tccttgtaac
    59521 ttatcttctg aaaattcttt tttgaactca tccagataag gttcatcata ctttttgcca
    59581 ttaatggtca actggtcatt ttccatcttg actgtatctc caggcatacc gatgatccgt
    59641 ttaacaatca tccgttcttc atcccccggt tcctttgtag taataatatc cattcgttca
    59701 tagtttgaga tcttagatga aatcaatcgt tgtccatcac ttaatgtagg gtccatcgaa
    59761 tgcccgttta cagtaactgg tgtaaacacg tacactctag ctaataaaat agccgctaat
    59821 acaaggatca aaatccccca atttttcaaa aattctttca cagcttacct cctacttgta
    59881 ttttcctcgt tatttattac gttttttcac aatacttcgt tgtactttct ttattctaca
    59941 atgtttataa atgaaaggaa agaataagtg atgtgttcgt cttatctttc tcgttatata
    60001 aaaaaggaac gtgacaaaag acgtgtcaca tcccccttat tccgaataaa cgtttttatc
    60061 gcaaccactg atacacggcg tttcatcaca ttatgaatgt cttcttcttt ggctacgact
    60121 ataaaccact ggttcttcct gcgactgtgc cttttttgca atcaatttca gacgataagg
    60181 ctcatgatag cgtaacccgt ctttgacaaa atcaccgccg acgatgaaca atccgacagg
    60241 ttccaatgtg tcttctgttg agtcaagtcg aatggtccct actttttcca tgtccgagta
    60301 gcttcgtcca atatttagaa catactcttt ctctcctgtt ttcttgacat agtaataagg
    60361 atacaatgta tttctatcga ccagaaatcc atccatgcga ccgagttcat ttgttttgat
    60421 ctcaccattt ccaatcaaat accgcatatt ctcggctaat ttcaattgat aatcttcgtc
    60481 ataagaaacc atgacctctt gtgtattcac tttatcgatc gaatttccat tatctatcga
    60541 ttcttctgtc tggatgttga acgcttcatc aggtaaatac ttcacaaaaa gctgagtgac
    60601 atcggctttc gtgtttttat ctaaaaagta ataaaataca tttaaaacag taaaataaac
    60661 aagcactaga aatgcaagtc catataagaa aaattgaaga tagttttggt tttgccaaag
    60721 tccataaaca attctcaata aataaagcgt gggaatcaca cttaaaatcg tatatccacg
    60781 gttaagatat ttaggactga tgtctaaata gccaaggaat ttatgcaccc cgttgataag
    60841 gtctagtaaa aatgtcattg agaatcacct gcttgctggt tatacgtttg ggtatttcct
    60901 gaatcttggt tttgctgtgc tgtacgtgct gcatcatcat tttgcgtgtt atcatctaca
    60961 gtcgtactgc ttggtatcgt ttcggagcta gcacttgtat ccggacttgt acttggattg
    61021 gttgaatccg atggagtgcc atctggtacc gtattacttg tttcgcttga gctgtcagtt
    61081 gtatatgtct catcatacga cgaactagtt gttgtatcgt cccatgtact tgtcgtagtg
    61141 gtttcattca aactttccgt tgttgttggt tcagatgtcg agactgaagt agttggtgtt
    61201 gtttcttcta cagtactaga acttgaactt ggtgcacggt agctggaact attcacaata
    61261 cctgtagtag tcgcgacaat cgtcgagatt gttaatacag cgattggctt caaaataggt
    61321 gctacttttc gcatcttatc tcttccttca ttgaaattta ttcttgtttc cttactttac
    61381 tacggacaaa ttatacagtc taccttattt ctaccataaa ttctttattt ttttcttacg
    61441 tttttccgaa agatttcttt aattttcctc aaaaactacg gttgatgttt ttaagtaagc
    61501 ttttgcttcc cgattgattt ctttcagatc gcatccttgc tgcttggcag cgaacacgca
    61561 accacaataa cattggcgat aaatatcata ctctttgcac atttgcaaag agcgttcata
    61621 gcctttgttt ttcttgaaat cacttggcaa gtattgtgtc ccgtaaatct tttggatatc
    61681 cattccgatc tgattgatca aagctgcatt tttctttggc gagatggtca gggcacttcc
    61741 aaagtaatcg tatcctagtt cttgcgcttt ttgcgcaaca agatctaatc gcatattgaa
    61801 gcatgcactg cagcgagcac caccttcttt ttcgttttca agatggtttg ttaaaaccat
    61861 tttggtgaat tcatttggac ggtattcatc aacgattagc gcaacatgat ggtcagtttt
    61921 ctcattaaat tggtctacaa atcgtttttg ttcatgtaat cttcgcaaat actcactttt
    61981 aggatgaata ttcgaatttg aaaaaaataa cgtgatctct gcatattgag acatgaattc
    62041 caatgtgtgc gtactgcaag gagcacagca tgtatgtatt aatatcttag gctttacttc
    62101 ttctttctcc cattgcatga tcattttttt cagaactgta tcataattta ttttttgatt
    62161 tttcattttt tctacgattt gttgagcatt aatcaatttg ttattcctcc tccttctttt
    62221 ttctaggatt ttccttatta taagccattt ctattttaat cgaaagctgt attgttatct
    62281 gtttgataat ttctttgagt attcctaatt ccccttgtat actggtagaa acgactattg
    62341 tcaggaggat agtactgtgc atgttgattt attctttcga aggctgcagc ggcgaggaca
    62401 gaagtttgct gccaatcatt tctcatcgat ccaaatcatc gttttttatt atatattgat
    62461 gacggtctta tcactcgttc tattttatat gccgattttt cgcgaaccag atagccatgt
    62521 ttcttttgtg gacatgctgt tcatggcaat cagtacagtg agtgtgactg gactatcgac
    62581 ttttgatatc aattctgtgt tcaatgataa cggtattata ctgctggaaa tattatttca
    62641 agttggtggt ttggggatca tgatgatttc tactgctttt gtcatttttt ctaaacgacg
    62701 gatcacactg aaacagcgac agctgatcat gacggatatg aatcaaccgc gtttgtctgg
    62761 tatcgtccga ctgattcgga tcacttttgc tattttaatc tggtttcaat tactttttgg
    62821 gacattcttt tctatttatt tttattacag aggctatttt gatcgttggc gtgatgccgt
    62881 tttttacggt ttttatcagg cgatatcggc tgtcacgaac tctgggtttg acgtcactgg
    62941 ggattccatc aagccctttg cacatgacta ttttttcttg atcctgatca tgtttttgat
    63001 ttttgtcgga ggaattggtt ttcctgtatt gatggagtgc cgggaatggc tattatacaa
    63061 acgttccaat gcgaagcttc cgtttcgttt ttccttgttt accaaattag ctgtgttagc
    63121 ttttgttatc ttgtttgttt cgggaactgt cttgatttat ctattggaaa aggaccattt
    63181 attccaagat tccaatatga gtgtcaaatg gatcaattcg atgttttatt cgattacgac
    63241 tcgtaatgct ggtctgcaga ttcacgattt gggtgatttt caaatcacaa cactgatcat
    63301 tttttcttta ctgatgttta tcggatgcag tcctagttct gtaggcggcg ggattcgaac
    63361 aactactgta gcaatcatcg gtttgtatct atattccttc ctcaaaagtg aagataacat
    63421 caatattttt ggacggagaa tcgatcaaga tgatgtgcga aaatcagtcg ttgtctttat
    63481 gctttctctt ggtatgtgtt tcttttgtat cgttttttta tctgctacag aagaacaaac
    63541 gctgatctcg atcatcatcg aagtaacttc tgcgtttgga acaactggtt tatctttagg
    63601 gattaccgga gacttgtctg ttgtgggcaa aatcacgatt gctacactga tgtttattgg
    63661 gcggatcgga atgctatata cattgatgtt attcgtgcca aaagaaacac gagatctagg
    63721 ctatgaatat ccaagcgaga aaattattat cggttaaaat gggaatatag gtaagaggga
    63781 ataataaaat cacagcagct tgaaacaatc attttgtttc aagctgtttt tttgttaaat
    63841 catgcgattt tgtccgattt catgcacttt cagccgtaac cttttcttaa gaataagaaa
    63901 agcaatttaa cctttttttc aacatatggt atgattagtt gaatttattc gtcagcaaat
    63961 cgtttttgga ggttacataa tgggaatacg cagtcatttt gcgattgcag ttggaaaaac
    64021 gtcgcaatgg gcattaaaaa ctttttttaa aggcggatca agtttaccag gtaaactagc
    64081 gctgaaagtc gatccacata tactagatag tttggcaaaa gactaccaag tcgtcgttgt
    64141 caccggaaca aacggtaaaa cattgactac cgctttaaca gtcaatattt tgcgccagca
    64201 attcgatgaa gttctaacca accctactgg tgcgaatatg gtacagggaa ttgtatcgac
    64261 tttcttgcag gcaaaaccaa aaaaaggaca gaaaaagttt gctgtcctag aaatagatga
    64321 agcaagtttg agcaaagtca cagaatatat gaaaccagaa ctgttcttat ttacaaatat
    64381 tttccgtgat caaatggatc ggtatggaga aatctatacg acctataaaa tgattgtaga
    64441 cggtgccgca aagtcaccaa atgcaacgat tatcagtaac ggtgattcac caatcttcaa
    64501 ttctatcgaa acagtcaatc ctagaaaata ttatggcttt gaccatgaag aagatcgtga
    64561 acaaatggct cattacaata cagacggtgt cttatgtcca aattgtcatc acatcttgca
    64621 ttataaaatg atcacttatg caaacttagg gaaatattac tgtccaaatt gtgacttcaa
    64681 acgtcctgaa ttggattatc gattaactga tatggtacgg atggacaatg tgtcagcaga
    64741 tttcgtgatc gatggtcatg aatacggaat cgaagttggc ggtatgtata atgtctacaa
    64801 tgctttagca gctactgcag tggcagagta cttcaatgtc gatcctgata aaatcaaaca
    64861 aggtttagga tatgacgaga aagtattcgg ccgacaagaa gtcatcaata tcaatgggaa
    64921 aaaatgtaca ttagtacttg tcaaaaatcc tgtaggtatc aatcaagtaa tcgatatgat
    64981 tggtctagct ccttatccat tttctttagt ggctttatta aatgccaatt acgcagacgg
    65041 aatcgatgtc agctggattt gggatggtaa ttttgaaaac tttgccgata tggatatccc
    65101 agctgttatt tctggaggag accgtcatac agatatgact ttacgtctaa aagttgccgg
    65161 gattccagaa aataaattga cagaaacaaa agaattacca gaagtaatcg aaaaaatcaa
    65221 agaattgcca actgagcatg tctatatttt agctacttac actgctgtat tgcagcttcg
    65281 taaagaacta gctgctcaag gatttatcaa aggaggaatg aaccgtggct aattatgaac
    65341 tcaatatcgc ccacctttat ggaaatttga tgaacacata tggtgataac ggaaaccttt
    65401 tgatgttgaa atatatagca gaaaaaatgg gggtttcttg ccatacggag atcgttagta
    65461 tacatgaacc ttttgatgct gataaatatg acttggtttt ctttggcggt ggtcaagact
    65521 ttgagcaatt aatcatttca aaagacatcc agaaaaagaa agattctttg atcaactata
    65581 tcgaaaatga tggcgtcatg ttagccattt gtggtggcta ccaattgcta ggtcactact
    65641 acatgggagc taatggagaa aagatccaag gaatcagtgc actggatcac tacacgttaa
    65701 gtcaggaaaa taaccggttt atcggtgata tcgttatcca taacgaagaa ttcaatgaaa
    65761 cttattatgg atttgaaaac cacaatggtc ggactttctt aggtgaaggt gaacgacctt
    65821 tggggaaagt ggtacaaggt caaggaaata atggtgaaga ccaatctgaa ggtgtcattt
    65881 accgaaatgt cttcggttct tatttccatg gacctatcct tgcaagaaat gagaacctgg
    65941 cagctcgttt gatccgccta gctttagaac aacgttacgg taaagaattg gatctgccct
    66001 atcttgaagg acaaacagcc tagttattcg aaaaagggga atgtgacaaa
//
LOCUS       DBBGRF010000008        65466 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000008 DBBGRF010000000
VERSION     DBBGRF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 65466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.008"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            149..1012
                     /locus_tag="ACIZD4_000583"
     CDS             149..1012
                     /locus_tag="ACIZD4_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC5989540.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1141..2763)
                     /locus_tag="ACIZD4_000584"
     CDS             complement(1141..2763)
                     /locus_tag="ACIZD4_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC5989541.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3012..3533
                     /locus_tag="ACIZD4_000585"
     CDS             3012..3533
                     /locus_tag="ACIZD4_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HGC5989542.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3719..5449)
                     /gene="spxB"
                     /locus_tag="ACIZD4_000586"
     CDS             complement(3719..5449)
                     /gene="spxB"
                     /locus_tag="ACIZD4_000586"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGC5989543.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5614..6432
                     /locus_tag="ACIZD4_000587"
     CDS             5614..6432
                     /locus_tag="ACIZD4_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HGC5989544.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6535..6732)
                     /locus_tag="ACIZD4_000588"
     CDS             complement(6535..6732)
                     /locus_tag="ACIZD4_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989545.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6901..7479
                     /locus_tag="ACIZD4_000589"
     CDS             6901..7479
                     /locus_tag="ACIZD4_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HGC5989546.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7574..7711
                     /locus_tag="ACIZD4_000590"
     CDS             7574..7711
                     /locus_tag="ACIZD4_000590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989547.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8523..9026)
                     /locus_tag="ACIZD4_000591"
     CDS             complement(8523..9026)
                     /locus_tag="ACIZD4_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC5989548.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9385..10410
                     /locus_tag="ACIZD4_000592"
     CDS             9385..10410
                     /locus_tag="ACIZD4_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC5989549.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10733..11611
                     /locus_tag="ACIZD4_000593"
     CDS             10733..11611
                     /locus_tag="ACIZD4_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HGC5989550.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12087..12203
                     /locus_tag="ACIZD4_000594"
     CDS             12087..12203
                     /locus_tag="ACIZD4_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HGC5989551.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13131..13469
                     /locus_tag="ACIZD4_000595"
     CDS             13131..13469
                     /locus_tag="ACIZD4_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989552.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13563..13793
                     /locus_tag="ACIZD4_000596"
     CDS             13563..13793
                     /locus_tag="ACIZD4_000596"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HGC5989553.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14193..14564
                     /locus_tag="ACIZD4_000597"
     CDS             14193..14564
                     /locus_tag="ACIZD4_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HGC5989554.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(14838..15530)
                     /locus_tag="ACIZD4_000598"
     CDS             complement(14838..15530)
                     /locus_tag="ACIZD4_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC5989555.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15533..16318)
                     /locus_tag="ACIZD4_000599"
     CDS             complement(15533..16318)
                     /locus_tag="ACIZD4_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC5989556.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16555..17955
                     /gene="lacG"
                     /locus_tag="ACIZD4_000600"
     CDS             16555..17955
                     /gene="lacG"
                     /locus_tag="ACIZD4_000600"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGC5989557.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            17980..18297
                     /locus_tag="ACIZD4_000601"
     CDS             17980..18297
                     /locus_tag="ACIZD4_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGC5989558.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18310..19983
                     /locus_tag="ACIZD4_000602"
     CDS             18310..19983
                     /locus_tag="ACIZD4_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HGC5989559.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            19997..21628
                     /locus_tag="ACIZD4_000603"
     CDS             19997..21628
                     /locus_tag="ACIZD4_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HGC5989560.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22119..23684)
                     /gene="guaA"
                     /locus_tag="ACIZD4_000604"
     CDS             complement(22119..23684)
                     /gene="guaA"
                     /locus_tag="ACIZD4_000604"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGC5989561.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(23743..24666)
                     /gene="coaA"
                     /locus_tag="ACIZD4_000605"
     CDS             complement(23743..24666)
                     /gene="coaA"
                     /locus_tag="ACIZD4_000605"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGC5989562.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            24862..25467
                     /locus_tag="ACIZD4_000606"
     CDS             24862..25467
                     /locus_tag="ACIZD4_000606"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC5989563.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            25775..26791
                     /locus_tag="ACIZD4_000607"
     CDS             25775..26791
                     /locus_tag="ACIZD4_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5989564.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            26932..28233
                     /locus_tag="ACIZD4_000608"
     CDS             26932..28233
                     /locus_tag="ACIZD4_000608"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGC5989565.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28279..28941
                     /gene="deoC"
                     /locus_tag="ACIZD4_000609"
     CDS             28279..28941
                     /gene="deoC"
                     /locus_tag="ACIZD4_000609"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGC5989566.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            28962..29360
                     /locus_tag="ACIZD4_000610"
     CDS             28962..29360
                     /locus_tag="ACIZD4_000610"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGC5989567.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29426..30508
                     /locus_tag="ACIZD4_000611"
     CDS             29426..30508
                     /locus_tag="ACIZD4_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC5989568.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            30720..32282
                     /locus_tag="ACIZD4_000612"
     CDS             30720..32282
                     /locus_tag="ACIZD4_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989569.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32275..33408
                     /locus_tag="ACIZD4_000613"
     CDS             32275..33408
                     /locus_tag="ACIZD4_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989570.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33408..34364
                     /locus_tag="ACIZD4_000614"
     CDS             33408..34364
                     /locus_tag="ACIZD4_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989571.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34463..35629
                     /gene="deoB"
                     /locus_tag="ACIZD4_000615"
     CDS             34463..35629
                     /gene="deoB"
                     /locus_tag="ACIZD4_000615"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGC5989572.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35653..36471
                     /locus_tag="ACIZD4_000616"
     CDS             35653..36471
                     /locus_tag="ACIZD4_000616"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGC5989573.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36488..37195
                     /gene="deoD"
                     /locus_tag="ACIZD4_000617"
     CDS             36488..37195
                     /gene="deoD"
                     /locus_tag="ACIZD4_000617"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGC5989574.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37493..38179)
                     /gene="gpmA"
                     /locus_tag="ACIZD4_000618"
     CDS             complement(37493..38179)
                     /gene="gpmA"
                     /locus_tag="ACIZD4_000618"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HGC5989575.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38351..38932)
                     /locus_tag="ACIZD4_000619"
     CDS             complement(38351..38932)
                     /locus_tag="ACIZD4_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5989576.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39065..39748)
                     /gene="rpiA"
                     /locus_tag="ACIZD4_000620"
     CDS             complement(39065..39748)
                     /gene="rpiA"
                     /locus_tag="ACIZD4_000620"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGC5989577.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40067..40480
                     /gene="rpsL"
                     /locus_tag="ACIZD4_000621"
     CDS             40067..40480
                     /gene="rpsL"
                     /locus_tag="ACIZD4_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGC5989578.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40564..41034
                     /gene="rpsG"
                     /locus_tag="ACIZD4_000622"
     CDS             40564..41034
                     /gene="rpsG"
                     /locus_tag="ACIZD4_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGC5989579.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41128..43215
                     /gene="fusA"
                     /locus_tag="ACIZD4_000623"
     CDS             41128..43215
                     /gene="fusA"
                     /locus_tag="ACIZD4_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGC5989580.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43387..44574
                     /gene="tuf"
                     /locus_tag="ACIZD4_000624"
     CDS             43387..44574
                     /gene="tuf"
                     /locus_tag="ACIZD4_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGC5989581.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            44981..45289
                     /gene="rpsJ"
                     /locus_tag="ACIZD4_000625"
     CDS             44981..45289
                     /gene="rpsJ"
                     /locus_tag="ACIZD4_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGC5989582.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45320..45949
                     /gene="rplC"
                     /locus_tag="ACIZD4_000626"
     CDS             45320..45949
                     /gene="rplC"
                     /locus_tag="ACIZD4_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGC5989583.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            45977..46600
                     /gene="rplD"
                     /locus_tag="ACIZD4_000627"
     CDS             45977..46600
                     /gene="rplD"
                     /locus_tag="ACIZD4_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGC5989584.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46600..46890
                     /gene="rplW"
                     /locus_tag="ACIZD4_000628"
     CDS             46600..46890
                     /gene="rplW"
                     /locus_tag="ACIZD4_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGC5989585.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            46929..47762
                     /gene="rplB"
                     /locus_tag="ACIZD4_000629"
     CDS             46929..47762
                     /gene="rplB"
                     /locus_tag="ACIZD4_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGC5989586.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            47805..48083
                     /gene="rpsS"
                     /locus_tag="ACIZD4_000630"
     CDS             47805..48083
                     /gene="rpsS"
                     /locus_tag="ACIZD4_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGC5989587.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48106..48453
                     /gene="rplV"
                     /locus_tag="ACIZD4_000631"
     CDS             48106..48453
                     /gene="rplV"
                     /locus_tag="ACIZD4_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGC5989588.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48467..49123
                     /gene="rpsC"
                     /locus_tag="ACIZD4_000632"
     CDS             48467..49123
                     /gene="rpsC"
                     /locus_tag="ACIZD4_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGC5989589.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49126..49560
                     /gene="rplP"
                     /locus_tag="ACIZD4_000633"
     CDS             49126..49560
                     /gene="rplP"
                     /locus_tag="ACIZD4_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGC5989590.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49550..49738
                     /gene="rpmC"
                     /locus_tag="ACIZD4_000634"
     CDS             49550..49738
                     /gene="rpmC"
                     /locus_tag="ACIZD4_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGC5989591.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            49763..50029
                     /gene="rpsQ"
                     /locus_tag="ACIZD4_000635"
     CDS             49763..50029
                     /gene="rpsQ"
                     /locus_tag="ACIZD4_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGC5989592.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50087..50455
                     /gene="rplN"
                     /locus_tag="ACIZD4_000636"
     CDS             50087..50455
                     /gene="rplN"
                     /locus_tag="ACIZD4_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGC5989593.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50492..50800
                     /gene="rplX"
                     /locus_tag="ACIZD4_000637"
     CDS             50492..50800
                     /gene="rplX"
                     /locus_tag="ACIZD4_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGC5989594.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            50828..51367
                     /gene="rplE"
                     /locus_tag="ACIZD4_000638"
     CDS             50828..51367
                     /gene="rplE"
                     /locus_tag="ACIZD4_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGC5989595.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51386..51571
                     /locus_tag="ACIZD4_000639"
     CDS             51386..51571
                     /locus_tag="ACIZD4_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HGC5989596.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51607..52005
                     /gene="rpsH"
                     /locus_tag="ACIZD4_000640"
     CDS             51607..52005
                     /gene="rpsH"
                     /locus_tag="ACIZD4_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGC5989597.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52037..52573
                     /gene="rplF"
                     /locus_tag="ACIZD4_000641"
     CDS             52037..52573
                     /gene="rplF"
                     /locus_tag="ACIZD4_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGC5989598.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            52734..53090
                     /gene="rplR"
                     /locus_tag="ACIZD4_000642"
     CDS             52734..53090
                     /gene="rplR"
                     /locus_tag="ACIZD4_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGC5989599.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53111..53611
                     /gene="rpsE"
                     /locus_tag="ACIZD4_000643"
     CDS             53111..53611
                     /gene="rpsE"
                     /locus_tag="ACIZD4_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGC5989600.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53626..53805
                     /gene="rpmD"
                     /locus_tag="ACIZD4_000644"
     CDS             53626..53805
                     /gene="rpmD"
                     /locus_tag="ACIZD4_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGC5989601.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            53849..54289
                     /gene="rplO"
                     /locus_tag="ACIZD4_000645"
     CDS             53849..54289
                     /gene="rplO"
                     /locus_tag="ACIZD4_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGC5989602.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54289..55584
                     /gene="secY"
                     /locus_tag="ACIZD4_000646"
     CDS             54289..55584
                     /gene="secY"
                     /locus_tag="ACIZD4_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGC5989603.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55646..56293
                     /locus_tag="ACIZD4_000647"
     CDS             55646..56293
                     /locus_tag="ACIZD4_000647"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGC5989604.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56484..56702
                     /gene="infA"
                     /locus_tag="ACIZD4_000648"
     CDS             56484..56702
                     /gene="infA"
                     /locus_tag="ACIZD4_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGC5989605.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            56735..56851
                     /gene="rpmJ"
                     /locus_tag="ACIZD4_000649"
     CDS             56735..56851
                     /gene="rpmJ"
                     /locus_tag="ACIZD4_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGC5989606.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            56869..57234
                     /gene="rpsM"
                     /locus_tag="ACIZD4_000650"
     CDS             56869..57234
                     /gene="rpsM"
                     /locus_tag="ACIZD4_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGC5989607.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57262..57651
                     /gene="rpsK"
                     /locus_tag="ACIZD4_000651"
     CDS             57262..57651
                     /gene="rpsK"
                     /locus_tag="ACIZD4_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGC5989608.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            57731..58669
                     /locus_tag="ACIZD4_000652"
     CDS             57731..58669
                     /locus_tag="ACIZD4_000652"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGC5989609.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            58697..59077
                     /gene="rplQ"
                     /locus_tag="ACIZD4_000653"
     CDS             58697..59077
                     /gene="rplQ"
                     /locus_tag="ACIZD4_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGC5989610.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59349..60188
                     /locus_tag="ACIZD4_000654"
     CDS             59349..60188
                     /locus_tag="ACIZD4_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC5989611.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60164..61033
                     /locus_tag="ACIZD4_000655"
     CDS             60164..61033
                     /locus_tag="ACIZD4_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC5989612.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61023..61820
                     /locus_tag="ACIZD4_000656"
     CDS             61023..61820
                     /locus_tag="ACIZD4_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGC5989613.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62023..62769
                     /gene="truA"
                     /locus_tag="ACIZD4_000657"
     CDS             62023..62769
                     /gene="truA"
                     /locus_tag="ACIZD4_000657"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGC5989614.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63433..63627
                     /locus_tag="ACIZD4_000658"
                     /pseudo
     CDS             63433..63627
                     /locus_tag="ACIZD4_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(63815..64591)
                     /locus_tag="ACIZD4_000659"
     CDS             complement(63815..64591)
                     /locus_tag="ACIZD4_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC5989615.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            64714..65121
                     /locus_tag="ACIZD4_000660"
     CDS             64714..65121
                     /locus_tag="ACIZD4_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HGC5989616.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20824 a        11650 c        13800 g        19192 t
ORIGIN      
        1 ttcttatttc ttgaagctga ccacttctgt cacaacctct tattttgatt agaacttgcg
       61 aaaataaacc ggttaaagtg tgtctagcgc aagagatttg ctataataga cgataagggt
      121 aaaatgtaac gagaaggggt tgaaaaatgt gtatcaaatt gtaacagatt cttgttgtga
      181 tctgccatac catgtattag caaaagaaaa agttgatttt ttatcaatga atctccaatt
      241 gaatgatcaa gagttagtag atgacctcgg aaagacattc aattatgacc gctacatgaa
      301 tcagctgaaa aatggtgcga tgcctacgac atcacaaatc aatgttggcc gatatttaga
      361 atttttccgt tcttatgcgg aaaaacagat tcctgtttta tatgtggctt tttccagtgg
      421 attaagcggc tcttacagta gtgcgcttca agcggttgaa ttgctgaagg aagaatatga
      481 agaccctgag atctatgttt ttgatacaaa agctgcaagt attggggaag ggcttttagt
      541 attggaagct gtaagattga aaaaagaagg taaaagcatc gaagaaaccc tagagtggct
      601 ggaaagtaat tatttgaaag tccattcatg ggtaacagta gacgatctga aatatctaga
      661 acgaggcggt aggatttcca aagcaagtgc tactcttggc agtctattga gtgtaaagcc
      721 tattattacg gtggataaag aaggaaggct gacgaatgtt gacaaagttc gaggaagaaa
      781 caagtcgatc cagacaatcg tcaatgagac ggtaaaaaca atcgttgcac cacttgatca
      841 aatcgtttat gtggcttacg ctggggatct agagagcgcg gagaaggcaa aacggctttt
      901 ggaagagcag ataaagatga aagatgtgaa gctttatccc ttaggaccaa cgatcgccag
      961 tcacacaggc tatggctgta tcgcgatttt ttcgatggga atcagtcgat aaaagcagta
     1021 actcattctg taaaaaagcc cagaaattga ttgtaacaaa aacagcgact cttaaaagat
     1081 agatgagcat cctatctctt agaggtcgct gtttttttat tttttaagct aaataggcca
     1141 ttatgcccat aactcgttca attgtttttg aatatctgca ttttccaaaa attcatcata
     1201 tgtcgtatca gctcgatcga tcacaccttt atccgaaacg gcaatgatgc ggtttgccaa
     1261 tgtttggata aattgatggt catgtgacgc aaataagatt gagccagtaa atgccatcaa
     1321 gccgtcattc aatgctgtga ttgattctaa gtctaaatgg ttcgttggat catctaatac
     1381 aagtacgtta gctttcgaaa gcatcatttt tgaaagcatg caacggactt tctctccacc
     1441 agataaaaca ttcactggtt tcaatacttc ttcaccagaa aacaacattc ttcctaagaa
     1501 gcttcttaag aaggtgttat catcttcttc tttacttgca tattgacgca accagtctaa
     1561 aatcgttaga tcagtatcga attctttcgt tgtatccttt ggtaaataag aattacttgt
     1621 tgtcacaccc caacgtactg ttccagtatc tggcgtaatt tcacccatga taactttgaa
     1681 tagcgttgtt gttgttatat cattttctgc gacgaaagcg accttgtctt ctttgctcaa
     1741 attaaaagat atatcatcta aaattttctt tccatcaatc gttacactta cattttctac
     1801 ctgcaataag tcgtttccaa tctcacgttc aggtttgaat ccaacgaatg gataacgtct
     1861 agaagaaggt tggatatcgt ctaaagtaat tttttcaagc atttttttac gtgaagttgc
     1921 ttgttttgat tttgatgcat tcgcactaaa gcgggcaata aattcttgga gttctttgat
     1981 ttgttcttct tttttggcat ttgcgtttgc ttgaagttta gccgctagtt gactagattc
     2041 caaccaaaaa tcataatttc ctacataaag tttgatttta ccaaaatcta gatccgccat
     2101 atgtgtacat actttgttca aaaagtgacg gtcatgggat acaacgatca cagtattttc
     2161 aaaattgatc aaaaattctt ccagccaatt gatcgattgg atatccagac cgtttgttgg
     2221 ttcgtctagc aaaagaacat caggtttacc aaatagtgtt tgtgctaata acacttttac
     2281 cttttgtcca ccagttaatt cactcatttg ctgatggtgc aattcttcag ggatgttcag
     2341 accttgcagt aaaacagctg cttctggttc agcttcccat ccattaagct cagcaaattc
     2401 tccttctaat tcagctgctc gaataccatc ttcgtcagtg aaatcctctt tcatgtaaat
     2461 cgcatctttt tctttcagca cttcatacag acgcttgtgt cccatgatga ctgtttcaag
     2521 tacagtatag tcttcatagt cgtaatggtt ctgtttcaat acggccatcc gttcatctgg
     2581 tcccatagta acggaacctg tggaaggctg cagatcccct gataacactt taaggaacgt
     2641 tgatttacct gcaccatttg caccaatcaa gccatagcag tttccggggg taaatttaat
     2701 attcacatca tcaaatagtt tgcggtctga aaagtgcaaa ctcacatcat ttacagtaat
     2761 caattttttt cctcactttt atcattatta gttttgacaa gtcttataga attatatagg
     2821 ggaaaggtaa aagattcaag gcaatcgaac attctttgtg tttcacgtga aacagaatga
     2881 aaaaaataaa aataaaagcg gagcgaaaat agctactata ggatttatta gtttgcaaca
     2941 gcataatttt tgacgttatt tataagaggg agtactataa aactgtaaaa gaaatgaaag
     3001 aaggattgaa aatggatgaa aaaagaacca tcgactgggg ctcattgatt ttgggaattt
     3061 tatttgtact tgtctcattg ttatcatttc aagaccctgt cggaaattta gttgcaattg
     3121 tagtagtctt tgcgattttt gcctttatta aagggatatt tgaactgttt gtacggaaca
     3181 gattaaaaga gctaacagga tataaaggaa agatgccctt aataatcggg atcatcgata
     3241 ttctagttgg cgtctttttc ttattcaata ttggtgcagg agtcgcagca ttgccttttg
     3301 tttttgcagt atggtttatt gctgattcag ttttagcgtt atttactgct gacttggcaa
     3361 gaggagtaag tgaaggatat tattggttta cgatcatcgt caatatttta ggaattttat
     3421 taggaatttt cttattgttt aatccaattt cttctgcgtt gacattaagc tttttagttg
     3481 gattctattt tatgttattt ggtatcacac atatcgtcta tgcatttaga taagtaaaat
     3541 caaacaaata aaaaagccgg cttccgatta cagttttact gttgtaattg gaagccggct
     3601 tttttatcat ggacaaatat gcacgaggtg atttttaggt gtcgagacaa atttatgcaa
     3661 aaatgtgaga agctatatac acaaatttta tcttaatact cgaagcatag cgcagttgtc
     3721 acaacctctt ttcatataat tcattcaata ctggcaaatc atggacttca tatttttctt
     3781 tgaatgcttg gatttcttct tcagaatatt ttcttggatc taaatgcaga tcttctactg
     3841 gcaatgggcg cttgttattg atcttcacat cgattactac aggacgatct gattttgcag
     3901 ctgcatcaaa ggcaaatcga agttgcgagt attctgtgac tgtaaagcta tttgccccga
     3961 gcgcttctcc aactttaccg aaatctgcat cttctaaaaa tacaccaaat ttcttttgtt
     4021 ccgtatcttc ttgttctgct tcgatgaaac caaaagaatc attcgaaaag acaacattaa
     4081 taattggaag ctgatatttg acttgtgtaa tgatatcttg catgaccata gcaaacccgc
     4141 catcaccact taaggtaaat acttgttttt ctgggtagct tagttgtgcg gcaattcctc
     4201 ctggcacacc attacccata gttgcgaacc atccagatgt cgtatgtttt tgtttaccgt
     4261 tcatattcaa taaacgaata gaatggatag tcgtgttacc gacatctgtg acgaaaatcg
     4321 catcgtcttc agcaatacga ttgatttctt tatagacagc ctctggacga atcggttctt
     4381 cctctcgatc ttcaaaagat ttcaaccaat ttacccattt ttctttattt tcttgatttg
     4441 ctaggtacca gctatcagca gggcgagcat cccctaactc gacaagtctt tgcaaagctg
     4501 tgtttgcatc accgaggatc gacaaagatg tttcatggcg tcgtccaaat tttgacgcat
     4561 cgatatcgat ttggataaat tcagcagttg gattaaaaaa tgcacgtcca aatgggaagt
     4621 cgctaccgac aaataagatc agatcggctt ctgccaatgc ttcatttccg ggtttagtag
     4681 cgacacgtcc agcaaaacca agaaagtttt cataatcatc aggaataatt ccttttgcta
     4741 gaacggaagc gacaacagga actgaaaaat gttctgagaa ttctttgatt tgcggaaatc
     4801 cgtttcgcgt tccttgacca acataaagaa ctggtttttt tgctttttca agataaggca
     4861 aagcagctag caaatctttt tcttctggta atatcacact tgttttgtga gtgtgagcgg
     4921 tggagaaagg ttgttcgtca atttcttcaa aaccaagatc aacagggata gtcacgatag
     4981 ccacgccttt atgctcatag gcggctttaa tggcttcatc tactacatgc ggaagacttt
     5041 gtggtgtcat gactgtacga ttgtatacgc taacatctgc gaaaatagga ttttcattta
     5101 gttcctggaa agagttatag ttcatggatg tagaagcaac ttgtcctaag aacgctacta
     5161 gaggcacatg gtccatctgt gcatcataca aaccattgat caaatgtgtc gcaccaggtc
     5221 ctgcagagcc gaagacagcg ccgactttcc ccgttaattt tgcatctgca gcggctgcga
     5281 gtgcgccgac ttcttcatga cgaacttgaa tgtagttgat ttcggttttt tcttgatata
     5341 gcgcatccat aattgaattg aaagatcctc cgggaatgcc gtaaatatgg tcgatacccc
     5401 agctttcaag aacttttacc attgcgattc ctgcattgat ttttgacatg gtgtttcact
     5461 cctttagcaa tgatgataca taaatttttt gtatctagag tatagaactt tttatcgaaa
     5521 atcccaacta attcgtcttt tcacaaaaat gtagtcatgt ttttgggaat atgctagagt
     5581 agtacataga tagattcaag agaggggaat ggcatggttg aatggctatt gagacttgaa
     5641 ccttggcagc aagcacttgc tgggacagct tttacttatt ttatgacagc tcttggtgcc
     5701 gggttggttt ttttctttaa agaaatcaaa aaagaagtgc taaacttgat gttaggattt
     5761 gcttctggtg tcatgattgc tgcaagtttt tggtctttgt tagatccggc tattacaaaa
     5821 gcagaagaaa atggagatat tgcttggcta gttgtaagta ttgggtttgg tttaggcggt
     5881 gtgtttttat atatggcaga taaaacactg ccccatatgc attttggacc acaacatgaa
     5941 gcagaaggat tgcctaccca tttaaaacgg acgatcttgc ttgttttttc tattacattg
     6001 cataacattc ctgaaggttt agccgtgggg gtagcattcg gtgcagcagc aactgcggat
     6061 aatccgacag ccgctatatt agccgctgtt tcggtggcgc taggtattgg tatccaaaac
     6121 ttcccagaag gagcagctgt atcaatcccg ttgcgacaag aaggtctgag tcgtaaaaag
     6181 gcctttgttt acggacaagc ttctggaatc gttgaaccaa ttgctggagt gattggagcg
     6241 ctactagtaa cgaaagtgga gctgctgctt ccttatgcac ttgcttttgc cgcaggagca
     6301 atgatttatg tcgtggtgga agaattgatc cctgaagcac agcagacatt gtccagcaaa
     6361 catcattttg cagtttttgg cgtcatgagt ggatttatca ttatgatgat tttggatgtg
     6421 gcattaggat aaataaaaaa aatatatatg atatatcaaa tagggccgcg aacttatatc
     6481 gcgaccctat ttttttagta agttatatca taatgaagtg aatggtatca tacattaata
     6541 atagtttttt ctatgtgtat ttcctttgat ccagcgaaca agccagatga taagtgcgat
     6601 tgggattaga actttgaccg caaaccataa aagcccgctt aggacactga caaaaagact
     6661 gatgacgaag ctagctgcaa ttagcactaa aagaaccatg aagatattta agaacatatt
     6721 tttttgacgc atacaaaacc ctcctcttgt tcattcttta ctatagaaaa agtataacag
     6781 ggattgttta aaaacacctc caactgaaga ctgattttta cttcatctac ttaaatgatc
     6841 aaacaattgc tttttctctg gtttatcatc taaaatagag cggaaaagga ggagaatatc
     6901 atgcctaaaa atcgtcttga agcatttaca gatgctgtaa tcgcgattat catgactatt
     6961 ttagttttag aacttcatga acctaacgga gacacgtggg aggcgctcgc tgcattaggt
     7021 taccgatttt ttatctatat tgtcagtttt atcattttag cgatttattg gaacaatcat
     7081 catcatttat ttcaagttgt acataagata aatggacggg tcttatgggc gaacagtttc
     7141 tttgtttttg cgctttcgct ttttccgttt gcaacttcat ggatcagtga gtacatcaat
     7201 agcctggctc cagaaatgac ttatggtttt gttaccttga ccgctaatat tgcgtattat
     7261 atcttggcaa aagaacttgt caaagcaaat aaaggccacg agaaagcatt gaaggcgatg
     7321 ttgaataatt acaagaaatc gtatctatcg attggtttga atgtgttagg aattgtctta
     7381 gggtatttag tagcgccagt agccgtgctg atcgcaaaca tcgtgattct agctgcttgg
     7441 atcatcccaa gtcgtaccat cgaatcacaa tatcggtaaa atgatccgtg tttaaaattt
     7501 aagagaaaaa tatagaaaaa ataaataaac gatcaaatat ccgagtgata ctagtattca
     7561 aagagggatg cagatggatc aaaaaagaat tcatgtagga ctgattacta gttttgtcac
     7621 gatgcttatt tatttggatc aaggtcattt gacttggaca gtagttggtg tcgtaggatt
     7681 tttgacatta ttcacagcaa taaaaaaata aacatcttta tgtaatctga tgttctatct
     7741 atttaagaaa agcatgttta cagcagtatg attctgttgt aaacgtgttt ttatttgtgg
     7801 aaaatttaat ttttagaaaa gtgtatcgaa aaatagatag ttagtttttc cacagtggat
     7861 aacttcgtaa gagataaaaa taaaaaatta gtcaaagaag ggcgtataga tttcttttga
     7921 taggagatat acaacagaaa tgaataaata ttaacgtgtt ttcaaacagt ataaaacggt
     7981 gtggtttttg gaataaaaaa ataacatatc tcattttaca cttttgttat tttatactta
     8041 aaaaataacg acacagaaaa taccgtgtct cagatttctc tactacttct aaaaactact
     8101 gtttttttcc tttgaaatgc cttcaaaaag taggatcagg cagaatatac tggcagaatc
     8161 aaggagaagg gagcctaaat aaggagaaaa accatagaaa atataaagta attacttata
     8221 aaacaagctt tttatagaaa aataatatac ctgagtaggg tataaattaa gacggaattc
     8281 ctttctagat tgagatattg actaggaaga atgttaagat tttaagcctt taagctaaaa
     8341 aaaacccttt ttgttaaata aggggaatat agcctgtcag tttcaaactg caagtcgtcc
     8401 tgctgcaata atatagtaga ttagagatga aaatagattt ttttaaacca atgactgaat
     8461 aaaaagaccg tcatagatac acattggaat gtgtctatta cggtcttttt ttacgaacga
     8521 ttttattgaa gacggacagt tcgggtcaaa aataaaaaag ctacgatcag aaataagaat
     8581 aaaatgtatc ccaaaataat ggctagacgg tctaacttat ttgtcgatag atgtttgttt
     8641 agaagttgat aggcccataa acctatcagt cctcctgttg tattagttat caaatcagtg
     8701 atgtccgcta cgccaatacc gaataggaat tgaatcaatt ctgccaagaa gcttacaagg
     8761 aaaataatcc ctaatttttt agaaaaagaa agtctcttga aattgacatt caaaagcacc
     8821 ccaaaaggaa aaaagacaat caagttataa gtggtctcac gtaataccgt cgtattttca
     8881 aaagaaaaag tagaaaaagg gacgagattg acattgctgt aagaataagt gagaaattgt
     8941 ggaagattaa atgatagctt gaataaaatc aaccataata gaaagaataa ataaatccct
     9001 aataaaaatt ttgatacata ccgcatagac atctcctcca tttaaaaagt ataccatcga
     9061 aaaccgctga aaaatcataa aaaagtatga agtttaagga ccaacgtagt tatcgtacga
     9121 aaattagaag cttttttttg ttgggaatcc ggtttcttta acaaagctaa gatagcgagt
     9181 tgcttggaaa agttgctatc ttttttctgt caaaacgact cggaatgttc gttttttgtt
     9241 ctaatttctc caagttgttt actttttgat actaagttta tgaaaaatca agaaatagtt
     9301 gttatactag gtaatgctga caaacgggat tggcatttca tcttggttca gctttttttc
     9361 caattactag gaaggaggga tagattgttc aagacttatt ttcgtttcaa taaaatacaa
     9421 gataatcctt ttcgtatcat gaatctgatg ctacttatct ttattgtatt atggttaggt
     9481 tacataaatc atgatttttt gatttcaagt ttttcatcat tagggatctt tacttttttc
     9541 tattatcaaa acataccgat gaaatatttg ctgaaacgta tgtttctgat cggttgcgga
     9601 ctgttggttg ctttcgtttt ggggatctta tcgacttatg ttttatggct tgaaccattt
     9661 gccgtagctt tggttgcttt ttccagcaga ttcgtgttgc gattattcca tatttctaaa
     9721 ccaggtggct tgttttttgc gatgctttct gccatgggaa cgagcatgca gctgccaatc
     9781 gctcaattac cgatcgtctc actttatttt tttatgggtg tcgtttttgc cctgattgcg
     9841 gcagtgatta caaaattact ggattcacgg cctgagcaga caattgaaaa agcaacttta
     9901 aaagaaagat ttcacgaaga gcctttagtg atcattgatt ctgttttcta cagcgctgcc
     9961 ttatttcttt ccgtttatgt cagtcacggc ttgaatctgc ataatcctta ttggttgacc
    10021 ttgtcatgtg catcgatttt gctagcagaa aacttggatg cgatgaagca tcgacaagtc
    10081 caatatctga ttggatcgat gggtgggtta tgtgtgtcgg cattcttgtc atttgtgccg
    10141 tttacgcagt tgcagaccat ttttctgatc acttttctat atggaatcgc acaatttcta
    10201 gttgctagaa attatgcagt tgctaatatt tttcttaatc cgatggcgtt gatgctatct
    10261 acacttattc gtggagcata cttgatttct ttgatcgaat atcgtttttt agggatcgtc
    10321 ataggaagtt tcatcggttt aggtgttgcg tgggtaatga cggttggttt gcaacattat
    10381 ttaacggttg ttcgtcaaaa attagaatag aaggacaaat atatgtgcca aaagaggtta
    10441 tgacaagatt tttgtcacaa cctctaattc aaggtgttca aaagccagat tctcagcatt
    10501 aagtcaaatt cacacaaaaa tgtggaaagg aactttcaaa aaaattttat atttattcta
    10561 tcaaaaaatt ttgtttatga tggtaactga ataaactttc ctgagatggt caatgctttc
    10621 cttgaaagtc ttacagatat tctttcttca tagaaagttt aagttttata gttagtgtac
    10681 aataaaagta tgtttatacc atatggtgtc cggataatca gtcatttaaa caatgaggtt
    10741 caaagatatg aaaaggggaa atttgatgaa gaaaataagc aatgaaatcc aaattctggc
    10801 agaaacttta actcttccca aagtcgttat agagcaaatg attgtacaag caaaaaacat
    10861 ccttgatgag gtgtttgagc aatatagtca tgaactaatg gatcctaata aagcaaaggc
    10921 gactgcaaag aaaatagaca aagtctatga agaggaacct tttgcagcat tagctattta
    10981 tctatatgca gcttctcaaa gttggaaaaa aatttatcaa ccattgaaga ttccaagaac
    11041 tatctatttg gcaacaatga atgcttttac tagatttatt catgaacatt tccaagtaac
    11101 aggaagctat cgctttgacc gtggtttttg gatttggcat tacactagtg gcttgatctt
    11161 tcggattggt gaattggagt acgaaatgac atattttccg aaagggtaca cggatctaag
    11221 attagaagga aagcagtgcc tttctcttca tattccttcc gatgcagatt tatctcagaa
    11281 taagataaga gatagttacg aaagtgccat tcgttttttt gaactttatt ttcctgatta
    11341 ccattaccaa gtgatgtaca cagatacttg gttactatca cccaatctta ctaaatggtt
    11401 gaaaaaagag tcaaaaatct gtctttttgc agccgattat cgattattat cagttgatga
    11461 acaggacgat agtggagtcc cttggatctt tggacgagta gatgcccaaa tacatgatta
    11521 tccagaaagt acgagtttac agcgacaagc aaaagagcaa ttgcttgcag gcgagcacat
    11581 tggctctggc ttaggtattc ttacttcata agtttagtac ttcgaaatag tttaaaagag
    11641 cgtgagacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcggaa
    11701 gcagaagcaa ctccttcgga aataagctga aattcacaaa aatttgaaaa gcaattttcg
    11761 tgaatttctt cttatttctt ggagttaaac gcttctgtcc cagcctcttt tttagtgttc
    11821 tatcgaacac acagtacgtt caataggtaa actagctata acaatagata ttaaagttaa
    11881 cggacaagag ggcctttttt aggtagctaa aacgtaataa tgaaaattta tttccagaga
    11941 taggagtcaa tcagctagtc tgatcgactg ttttaacaag ttgactttca ttttaacttt
    12001 tgataccatt taaaacacaa atcgtaattg tttcgatttg tgttttttag catgactaca
    12061 atcaaagaag aaagtgggtc gtccatatgg aaaaaacaga tatctcaagt gcataccgcc
    12121 gcttgaaaag cccaaatatc aaaacacgaa aacgtgcgct gaagatcatc aaagatgtga
    12181 aacggaatag tgggaaaagg taagaagaag gaaacttaat taaaaaaata gccgaaaaac
    12241 gtttttcggc tattttcaat aatcggtttt tgtgtaaggt ttccgaaaga actgctgttg
    12301 attttccatt tttaacatat gataaattgg tagaatcttt cttttcaaat tgataccatt
    12361 ccctaattcc agttatatag ttaactacag aaccacaaag cacgtacgtt tataaaagta
    12421 ttatctgtag ttatttttca attccctttc aacctcttat tttgaccagt agtattgatc
    12481 actttacctt ttaacacctt tgttcgtttt tgaaacattt ttagtcaaga atggaaacgt
    12541 aactacataa tcaaaggttt tgcgaaatat ttcatgaaat atttcatgta gaagcgagca
    12601 atacggttgc aaataaccat tatcgtttaa taagcagtta cgaaagctcc caatatctct
    12661 aacgttcagc tcactccatt tcttttcttc aaaaaaatca gtgattcgta tctctttcta
    12721 tttgtcgaaa aagttaactt taaaaagtaa cgccgaaaaa atatgcaaaa aaataaaaaa
    12781 gcagttacta ttgctagaat aacatcaagg aataataagt tttggttttc agataatagt
    12841 cgataagttg tgtattggaa ttttagatac agtaataaag tatttttcat gaaattttgt
    12901 gagaatcact attacaagta tctttaataa aattaatggt taaggaggaa cttaaagtag
    12961 aatgtaaatg aatagttgta gtcagtcgat tgtgatacta gactcaaagt tgcaggaata
    13021 agtttttcaa tttgtgattg gaagataaaa aatgaaaaag aagggctttt ttttatactt
    13081 tgttgattgt agtgtttatt ttccctctgt ttagccaagt aacattttct atgactcaac
    13141 cagtttcaag tgaggaacat gataaccttt ttcgtgctac agaagagttt aagaaatatc
    13201 aggaaaatat tgttccggag actccattag ctagtgagcc aattactgat attgatggaa
    13261 accaaatagg atggtatata cagtacgaag ttatggtggt aaataatgac tcaatagtaa
    13321 aaaatacagt aggcttagag ctaacaccga ttgaaaaggt gagttcattg ttaacgtata
    13381 tttatactga tgaaagtgac gagactgaga tcattttaac ggattactca aaaattgcta
    13441 ctgataaaaa gtatatattg tggatgtaga cactagtgaa atactttatg atatagaaat
    13501 tgatgaaaat ttactagatg tagcacaaga aatcgatcat caaaagcagg aagctattcg
    13561 atatgctggt agaaaaggga aaagaaaata tttattacgt gaatgtagca aaagttagag
    13621 aagatgaaaa tgagtggaaa gaattcaaga gtcgctactc aattaactcg actccgacat
    13681 ttacagttta cagagaagga tcgatagaaa aaactgtttt ttggactaaa gaaagtggaa
    13741 tgtctttagc tgaagtagaa gagtttttgg attatgttag tatgcaacag taagggagtt
    13801 cttattatga aaaattttga cacatattat gttattgttt tttcgatatc tttgctgtta
    13861 atattactaa ctttaatgca gtataaagag tatccagagt attttatttt aacttttgta
    13921 tatttagtaa gtagctacac acttctatat aaattcagaa gttcttctag agtttctaaa
    13981 gtttgtttct taattagctt attgattcta taatattttt gatttatata ggaaattaaa
    14041 aatattatag aatcaacact cagagaacgg gttggttttt aatagattta ataagtactg
    14101 ataatgaaat ttctcctggt tgggaaaacg aagttggtta ccctgtagaa gaattttttc
    14161 aagattactt tgcggagtat gccgatagga taatgagaga ttacgtaaca gataaaactc
    14221 aagaagtcat caatcaatcc cagtcattaa atgaattatc tgataaggcg aaagaagaag
    14281 cagttgccat tatttcttca gggattagtg actatattga tatgagtggt gaaatcaatt
    14341 atggcgataa agacaaaatt gtacgcatga taaaagcttt tatcaaaact tttgatgtga
    14401 aggcagatct taagtttaat gatacttacc tagtaggaaa attaattaat atccttggga
    14461 cagagaaaga tacggaaacg tttatttcct ctttgtctat gttgtttaca gataagcatt
    14521 tttcaactca gcttggtgga gaggaactag tggaaatctt ttaaccatta cgcccagcat
    14581 taataaaagt atatcaaaaa agtactcctg atgattttta agattggttt gagaaataat
    14641 gtgaaaacac tatttttaat gttaattata gatagagatg aacgcgtcat atggttaaaa
    14701 gaatgaaaaa gtcaaagata cactgctata tttcactaag gatatagcag tgtatctttc
    14761 atgtcgtttc actggcagtt ttttataaaa ggaggtgtgc atttcagttg cttttctttg
    14821 gtagttagtt gaatcgttta agaattaacg gatgtggcag acaggtgctc tgtccaaaaa
    14881 ccagtaaaat ctttgatggt tccatcttta tttagctgtg cctgttcaaa tactgttttg
    14941 tttttaccga atggatcaat tgcaataatt gttccgatcc ccgcacgttt ggcagcaagt
    15001 aatcctgagt aagcatcttc gataacaaga caatcagccg gagctaagct cagtttgtct
    15061 gccgctttaa gaaaaatatc cggttgcggt ttcccaggga aagagccgtc gtcatagaca
    15121 atcttgtccc agtcaaacca gcgggctaaa tcgaaaatat caaaataaaa agcaacattc
    15181 tctttgacag tagccgtggc aatcgttaat ggaatctgtt ggtcagtcag ctggtcaaga
    15241 gtcgcttcaa gcccttttgt caactgaagc tcgttttcat tttgcaagca aagcatacga
    15301 taatagcttt ctttttcttc tgacaatacg gcgatctcag aggcggtcaa atgctctgaa
    15361 atgaaatgtt tcaaaatctc cgtattcgtc cgaccatgaa tattttttaa aatatcctcg
    15421 tctgataaac catcttttgt atgatcatgt atcatatgca gccaagcagc ttcatgcaga
    15481 tgagagtcca aaaacattgt tccgttgaaa tcaaatataa tccctttcat agttacgctc
    15541 ctatagtggt attttcggtt gaatcagcaa tttgcagatc gacatattgt gcatagtgct
    15601 cttgaacctc ccgcgagatc tggcgatccg taatgagcag atcgaaatca tgcaaattat
    15661 aaaacacata aaaatcatct cgattgaatt ttttattatc aacgagtaga tatttcttac
    15721 gggaattatt tagagcgatc tgctgtgctt ctccttcttc ggtactgtaa gtagagatcg
    15781 cttcgttgtg aacgccattt gaactgataa atgcttttgt aaactttagt cttcttaaat
    15841 tgtcgttggt gatcggtccg acaaatgcgc cggtattttt ccggaaatca ccgccaatca
    15901 gtagaatttc tggtccatct gcttgagcaa gaatatcaaa aactggataa ttatttgtaa
    15961 tgatccgaat tttcttgttc agtaaatgcg tcgccaatag ttcgattgtt gtacctggtc
    16021 ctaagaaaat cgtttctccc tcgtgaatca aggaggctgc tgtggcagca atttcttttt
    16081 tttcttgaat ctgcagagtg gctttttcag tgtgagaaag ttcttgatct aaagtgtagg
    16141 aaagactttg agcccctcca tggacacgca gcagcttgcc cgatttttct aattcatcta
    16201 aatctctgcg aacggtcata tcagaaacat ctaattgatt gatgatttca ttaacggtaa
    16261 ggattccttt tttattgacc atttctacga tagtaagcaa tctttctttt ttcaacattg
    16321 tcttcacctc taatttaagg ataatctatc atataaacgg acaacagtca atctaattcg
    16381 aacaaaagta aacatttagg gtggttttta tgtttgttac aatagatttt attgctgttt
    16441 tctggttttt atgattattt gtgtttgttt ttgttgacaa atgttttgga tgcgtttaca
    16501 atgcaatcag ttagaaagag cgaaaactga ttatagattt gaggagagat gtacatgctt
    16561 aaattaccag aagattttat ttttggcgga gccacagcag cctatcaggt tgaaggagcc
    16621 actaaggaag gtggcaaagg cgctgttgct tgggatgact ttttagagga acaagggcga
    16681 ttcagtcccg atccggcaag tgatttttat catcaatatg caaaggacat tgaattgtgt
    16741 gaacgttttg gtgtaaatgg tctaagatta tccattgctt ggagccgcat ttttcctgat
    16801 ggagctggga aaccaaatcc agaaggaatc gctttttatc atcgtgtgtt cgaagaatgt
    16861 aagaaaagaa acgtaacgcc gtttgtgacg ttgcatcatt ttgatacccc taaacgtttg
    16921 tttgaccatg gagatttttt gaatcgagaa acaatagaag catttgtttc ctatgccatt
    16981 ttttgttttc atgaattcaa agaagtcaag gtgtggagta cctttaatga aatctatcca
    17041 gttgcaacca atcaatattt gttaggtgtt ttcccaccag gaatcaaata tgattttaca
    17101 aagatcgtcg cctgtcttca taatatgatg gttgctcatg cccgtgtagt gaactatttc
    17161 aaagaaaacg aacttccggg tgaaattggt gtagttcact cattagagac gaaatatgcg
    17221 gcaacagacg cgccggaaga taagcatgct gcctttttag acgatgcatt gtcgatccgt
    17281 ttcttattag atgctaccta tttaggctat tattcaactg aaaccttgac tgctcttgat
    17341 gagatatgtg aagcaaatca ggccagctat cattttcctg aagaagattt cgttgaattg
    17401 aaaaaagcat ccacgcgtaa tgactactta gggatcaatc actaccaatg ccattttgtc
    17461 aaagcttacg atggagaaaa tgcaatccat cataacggta cgggtgaaaa agggacctct
    17521 gtttataaag tgaagggaat cggagaacgt atttataaag aaggaattcc tcgaactgat
    17581 tgggactggc tgatttatcc agaaggtcta tatgacttgt tgctgcgaat taaaagcgat
    17641 tacccacatt acaacaaaat ctatatcact gagaacggga tggggtataa agatcagttt
    17701 gaagatggca ttattatgga tcagccgaga atcgactatt tgagagtcta tttggaatcc
    17761 ttaagcaagg cgataacagc cggggtaaat gtgaaggggt attttttgtg gtcgcttatg
    17821 gatcttttct catggacaaa tgggtataac aaaaggtatg gcttgtttta tgttgatttt
    17881 gaaacccaga agcgttaccc aaaagaatca gcttactggt acaagttggt cagtgaaacc
    17941 aaaacgatta tttaataagt gataatggag gaagaaaaga tgaataaaga ggaattacaa
    18001 atgcttggtt ttgagatcgt tgcatattca ggcgacgctc gcagtacatt attgaaatta
    18061 ttgaaagaag taagacaagg aaactttgaa catgttgatt cggcgttgaa agaagccgac
    18121 gaaaatttaa cccttgcaca taattcgcaa acaaaaattt tagcggaaga agcatctggg
    18181 aaagagatgg agatgggatt catttttatc catgggcagg atcatttaat gaccacttta
    18241 ttgctgagag atctgattca agactttatt gtactgtaca gacagaatca aggataggag
    18301 aagaacgcta tggatggaat cattaaacaa atcgaaaaag ggaaaccatt ttttgaaaaa
    18361 atctcacgta atagttattt aggagccgtt cgtgacggat ttttaacagc gatgccagct
    18421 attttatttt caagcatttt cattttgatt gctgcggttc ctgagatttt tggttaccaa
    18481 tggcctgaat ctgtctccac atggctatgg aaagtctata attattcgat gggtgttgta
    18541 gggttactcg tttcagcaac cactgctcgc tgcttggctg attcgatgaa tcgtcgctta
    18601 ccgaaaaaca aagtaatcaa caccacctct gtgatgctgg cctctgtggt aagtttcctg
    18661 ttgttaagcg tctctccgat tgaaggtgga ttttcaacgg aatatatggg gacaaaggga
    18721 ctactggctt cctttgtcgc tgcattttta acagttaatt tatataagtt ttgtgtgctg
    18781 aaagatatta ccattaaaat gcctaaagaa gttcctggaa cgatttcgca aaccttccga
    18841 gatatttttc ctttctcttt ttcagtattt gcggccgttt taattgattt aggcattcga
    18901 caaatcttcc aaatctcatt tgcagaagca atcattacgg tgctgcagcc gctatttaca
    18961 gcagctgacg ggtacttagg aatcgctatt atctggggag cgatggcgct gttttggttt
    19021 gtcggtgttc atggaccgtc gatcgtggag ccggcaattg cggcaattat ctatgccaat
    19081 gtggaaacca atctgcaatt gttcaattcc ggtgaacaag cttctaaagt actgacggtg
    19141 ggtttaggga attttgtagg aactatggga ggaactgggg caacattggt tgttcctttt
    19201 atcttcctac tctttgctaa gtctaagcag ttgaaggcag ttgggaaagc ttcctttatt
    19261 ccagtaagtt tcgctgtcaa cgaaccattg ctatttgcgg cacccatgat tttgaaccct
    19321 tattttttta ttccattttt gttaacacct gttgtaaacg tttgcctgtt caagtttttt
    19381 gtcgatgtat tgggcatgaa cagctttatg tacgttttgc cttgggcaac tccagcaccg
    19441 atcggtttgg ttctaggaac gggcatgggt atcttagctt ttgttctagc agcggttcta
    19501 atcgtcgttg acttcctgat ctatctacca ttttgcaaag catacgatgc tgtcttagta
    19561 gagaaagaag cacaaaaagc agaggtgatc gcaaccgagg aaggtgcttc tgccgatgta
    19621 cgtgaggaag tacctgtggc agcgagtcaa gttatcagcg atgcaaataa agaaatcaat
    19681 gtgttggtac tttgtgctgg cgcagggaca agtgcgatgt tagctaatgc tttaaaaaaa
    19741 ggtgcatctg aatcgaaagc accgatcagt gcaatggcgg gtgcttatgg ttctcattac
    19801 gaaatgctgc aggattttga tatggtggtc ttagcaccgc aagtcaattc ttactatgat
    19861 gatatcaaag aagacaccga tcgcttagga atcaagctgg ttgcgacaaa aggagcagaa
    19921 tatatcggat taacgagaga tcctgaaaaa gctgttcagt ttattctgaa ccaatttcaa
    19981 taaaggagga gccataatga aaatgggaat ttggttgcgt aaagctgttt tatttgcagc
    20041 tgtgttaggg gctttggggg ctgtttcaaa aactgttgaa gcatctgcca gcgaatttat
    20101 tcgcggagca gatatttcga tcctgtcaga tatggaaaaa tctggtgcaa aatattatga
    20161 agacgatatt tcaaaagatg ccttagagat tttaaaaaat aatggtgtca actatgttcg
    20221 actgcgtttg tggcaggatc cttataatag taatggagaa agttatggag cagggacaaa
    20281 tgatctggaa acgacgattg accttgcaaa acgagcaaaa aatctgggac ttaaggtgct
    20341 gctggatttt cactacagtg atttttgggt tgatcctggg aaacagaatc ttcctaaagc
    20401 atggcaaggt ctgacctttg aagaaatgaa tacggcattg tacgactata caaagaacgt
    20461 tctgtcggaa atgaagcagc tggacgttta tcctgatatg gttcagatcg gcaatgaact
    20521 gaatagcgga atgctctggc cttatggcaa gtcttgggga gaaggcgggg gagaatttga
    20581 tcgattggct gcttttttga agtctggtat ccaagctgtt cgagacactc aacctaaaac
    20641 aactccagta atgctccact tagctgatgg tggcgataca ggagcattta cttggtggtt
    20701 tgatgaaatc acgagtcgag gtgtgtcatt tgatttaatt ggagtgtcgt attatccgta
    20761 ttggcacggt tcaatgaatg aacttcaaac caatatgaat gcgatcagcc aacggtatgg
    20821 taaagaagtg atcgtagttg aaacagctta tgggcataca acagcgaatg ccgatactat
    20881 gccaaatgct tttggtgaag ccgaagcagc tgcgggggga tatgaaccaa caccgacagg
    20941 acaagcagag tatttgctgg atcttgccga tcggattcag gcagtaccga ataatcgcgg
    21001 ggcgggcttc ttctattggg aacctctttg gtacaacgga aatgtgagtt gggcaacaca
    21061 agcaggtatg aattatctca gtgttcaatc cactatggga aacgaatggg acaaccaagc
    21121 gatgtttgat tttgctggaa acgccttgcc aagcttgcgt gcgtttaaac aagcaggggc
    21181 gcaaataaat ctagttaaaa atgcaagttt cgaaagcgat ggaccaacga ccagtccttc
    21241 caattggcaa acctggtttc aacaaggaac cgctaagggt acgatcaaaa cggaagcggg
    21301 cacttttttt ggggactaca aactaacttt ttggcaggat caagcatacg aggcatcagc
    21361 ttatcaaaat gttagtggca taagcaaagg aacttacaca ttgagtgcct atgtaatgtc
    21421 tgggggagag tttgatacta atcagttata tatcaaaaat tatggtggag cggaactaaa
    21481 tactgcggtt gttaaaacaa gtgaatggac aaaaattaca atcaaagaca ttccaattac
    21541 aacaggtgtt tgtgaaattg gggtttatag caaggcttca ggaaatgctt ggacgaacgt
    21601 tgattttgtt tcattggtga aacaatagac tgcggatcgt ttcgattcaa gatcggaggt
    21661 tcccttcagc cacatcgtta gcgtagaagg caggaatcga acctgcacct cgcctttgcc
    21721 aaaaataacc agaaacgatt tccagtcatt tttaccaaaa cgagtaaagc accagacttc
    21781 atctacactt tgtattatgc taaagagagt tcaacgattt cgtaagaagc aatgaaaaaa
    21841 ttgcaaaaag ttgtgcagat aacataaagt ttgtttaaga aagggtaacc ttagaattcc
    21901 gtcgtgaata tgatttgagc acttagatgg atagaaaaaa gttctcggaa aacagttcgt
    21961 ttttcgagaa cttcttttta tgataagaat gaaacaaatt aacttatatt atagtctctt
    22021 ttggtaggga accatcttat ttttaatgaa aatcaagcat tttagctatt gaagaatgtt
    22081 gatttatagg gattccccct ccatattatg ttggctcttt attcccactc cactgttgct
    22141 ggtggtttag aagtgatgtc atacacgata cggttgacgt gggctacttc gtttacgata
    22201 cgtacagaga ttttttgcaa gacttcccat gggatacggg caaagtcagc ggtcattccg
    22261 tcgattgaag ttacagcacg gataccgact gtgtagtcgt aagtacgtcc gtcacccata
    22321 acaccgacag agcggatccc tggaagaaca gtgaaatatt gccagatatc acggtcaagt
    22381 ccagcagctg cgatttcttc acgcaagata gcatcagatt cgcgtacgat ttctagcttg
    22441 tcttcagtga tttcgccaag aacacgaata ccaagaccag gaccagggaa tggctgacgc
    22501 caaacgattg aatcaggcat gcctaactga gtccctaatt cacggacttc gtctttgaat
    22561 aatgtgttta atggttcgat caattcaaat tgcatatctt ctggcagtcc acctacatta
    22621 tggtgagatt tgatcgtctg tgctgtttct gtaccagatt cgataacgtc agtatacaac
    22681 gttccttgtg ctaggaaaga gacgccttct tcaccagcaa gttttgttgc ttcgtcatca
    22741 aaaacatata cgaattcatt cccaatgatt ttacgttttt gttctgggtc agatacacct
    22801 ttcaacttgt ctaagaagcg atctcttgca ttgactttga tgatgttcaa gccgaatttt
    22861 ccgcctagac tttccattac ttgttccgct tcgcctttgc gtagcagacc gtggtcaaca
    22921 aagatagatg tcaattggtc accgatcgct ttttgtaaaa gaaccccaac gacactagaa
    22981 tcaacgccac ctgaaagacc aagcaagact tttttgtcac caacttgttc acggattttt
    23041 tctacttgca tatcgataaa gttatccatt gtccagttac cttcacagtg acaaacatca
    23101 aaggcaaagt ggcgcagcaa ttcgattccg tattcggaat gacgtacttc tgcatggaat
    23161 tggataccat aaaaattacg tgttgtgtct tggatagaag caatcggaca atctttgctt
    23221 gttccgactg tttcaaagcc ttcaggaact ttagttacca agtcaccatg gctcatccat
    23281 actgtttgtt gttttggtgt ttctttaaac aagacagctt gatcgcttgt tacttctaac
    23341 aaggctttcc catattcgcg gtttttagca ggctctacgg aaccgccaag tttgtacgtg
    23401 atcaattgca taccatagca aatccctaat acaggaatac ctaaattgaa gatctcagga
    23461 tcgatcccaa atgcattctc atcatataca ctgtttggtc cgccagaaag aatgattccc
    23521 tttggattca tcgcttttac ttcttctgca gtaatgcggt ggctcaataa ttcggaaaag
    23581 actccaagat cacgaatacg tcttgtgatc aattggttat actgactacc gtagtctaat
    23641 acgataatct tttcaacgtt cgtcatatcg gcaacgtttg tcaaatttat tacccctatc
    23701 cctttaaatt ttatctcaaa atagtcaaac tattttaaaa tgctaatatt ttcgcatgaa
    23761 aatcgaatcg atgatatgat tttcagtttt atggagaatt atatcggctc ttcctcgtgt
    23821 aggcaagata tattcctgta aatttttcaa attcacattt ttccatacat cttttgccat
    23881 tttaaaggct tcttcacgat ctccgatagc aaaacgataa taataattct ctggattttg
    23941 gaaagccgta tccagtaacg caccaaaacg atccaaatac catttttcga tcagcacggg
    24001 atcggcatcg acatagacag aaaaatcaaa aaagtcgctg acgtagattt gctgattcgc
    24061 aggtaattga agcgtattga tcccctcaac gatcaagata tcaggctgct ggatcaattc
    24121 gtacttgtct ggaatgatat catacacatc atgtgagtaa acaggtactt ttatctcttc
    24181 ctgaccagat tttacacggt tcaagaaatc gatcagcatc tccatatcat aactttcagg
    24241 aaatccttta cggtccatga ttccacgctc ttttaatata cgatttggat aaagaaatcc
    24301 gtcagtcgtg atcagctgaa cgtttcttcg tttgaaggta cgagacaaaa tcgtctgcag
    24361 cagtctggct gttgtacttt ttccaacggc tacacttccg gcgatcccga taataaaagg
    24421 cggtacttct acgtatttat gaagaaataa acctttactc aagaacaaag attcaaattc
    24481 tttcatataa agataaatca gatgagcaag aggtacatag atatctcgaa catcctgcat
    24541 ggaaatgcgg tcattcaaac ttttgatatt atctagttca tcttgtgtca aaggtgcttg
    24601 cccattacga taaaattctc gccattcttc tcttgccaca cggtagtagt tcattggatc
    24661 attcatatta gcctcctgcg ttctcccatc aatggaacta ttttaacaca aaataaacgc
    24721 aaaccccacc acttaagaga gattgccgat ctttttgtat aatctttata atagaaagaa
    24781 acggagtctt attcttgact tgcgcacgga tacataaaag gatagactgt tgtcatgaaa
    24841 gaaatgagaa ggatggaaga catgacaaat cattactatt ctgaacgccc agatacggcg
    24901 cacgattttg aacaatgggc ttttgagtta aaaggcagaa cctttcaatt tgtaacagat
    24961 tctggtgtat tttcacgtga aacagtggat tatggttcac gtgtcctgat tgatgctttc
    25021 gattgggaag agttacctga tgaaggaaag atcttagatg tgggatgcgg gtatggaccg
    25081 attgggttag ctttggcatt tgcgacacag cggtttgttg aaatggtcga cattaatgaa
    25141 cgagcggtaa gtctagcgca aggaaacgca aagcgtaacc aaatcgaaca tgttgatatc
    25201 catcaatcga atatctatga agcagttcat gaagaaacct atgcagctat cgtaagcaat
    25261 ccgccgatcc gtgctggaaa aaaagttgta catgaaattt tgacaggcgc atatcctcgg
    25321 ttgaagaagg gcggtacact gacaattgtg atccagaaga aacaaggagc gccgagtgcg
    25381 caaaagaaaa tggaagaaac atttggtaat gcagaaatcg tcacaaaaga taaaggatat
    25441 tatatcatca aaagtgtgaa agaataacta gctgaaaaat agtggagcga cgaaagagtg
    25501 gaactgggcg tgcatgtacg ggtacgtatc agttcttttt ttgttgagaa gtttttaaaa
    25561 acaaagaact attttttctt caaaaagaaa tagtaggaac agagtcgttg ttttttacga
    25621 taaaataaat aagatacaga acttgtatag aaggctgcca agtcggtaga taaaggaggt
    25681 ttttatcaaa aaacatactt tccttttttc tctattcttt tcttgggggt tttggtacac
    25741 tgatagggaa tttagataga agggagccaa taggatgaag ctgaccatca gagatatcgc
    25801 agaaatggca ggcgtatcag taacaactgt ctcacagatt ttgaataaca aaggaagcag
    25861 atttagtgat aagacaagaa aaaaagtgtt gtcgatcgtg aatgaacatc attataagcc
    25921 cgattatttc gcttcaaatg tgatcaatcg acattcaaag accatcggaa tgatcgtccc
    25981 tgatgtcact gatttcttct tctccaaact gatcgaaggt gtagagagct atttgaatcc
    26041 tttgggctat gtgatcatgt tatgcaattc tcgtcatagc caagaaaatg agatcaagta
    26101 tttacaagag ctttcccacc gctcagtgga cggaatcttg ctggccacac caaatatttt
    26161 acctgagaaa tatgcattag acagcggttt ttatcaaaaa atgccaatca ttttaatcga
    26221 tcgcggattg aatcgtcggg ataacggacg gcttatcgta aaggaatatg agggcgccta
    26281 tcaagctgtt tcgctgttta ttgaaaatgg ccatacgaag atcggcatgc tgaaggaaac
    26341 cactggatac tatcaattag aagaacgttt caacggatat cgtcatgcgc tgaaagatca
    26401 tggcctgcct tttaatggga aatttgttga acatggagag ttgactgtcc aaggtggata
    26461 tactgcatca aaaaaattac tcaaacataa agatatcacg gctatttttt gcgggaatga
    26521 tgccatggcg atcggatgct atcaggcgat cgatgaattg ggcaaaaaaa tcccagaaga
    26581 tatctcagtc ataggattcg atggattaaa gctgtcagaa tacatgattc cgcaattgac
    26641 gacagtgcag cagccaagtt ttgatattgg attttatgct gcacgtttcc tgatcgatac
    26701 gatcgaattt cctcaaagaa aagttccgaa caaagtgttc gaaacaaaat taattattcg
    26761 tgagagcgta aaagtattga caaagggcta actcggcggt atattgctta tgtaagcatt
    26821 tacaaaggct agttagtgct ttttttattt ttagtaaacc agtttactaa agtggtttac
    26881 ctttcctaaa aataatgtat aataccgaat gaagacaagg aggatcaggc aatgcgaatg
    26941 gtggatctga ttgaaaaaaa gagggatgga aacgagctgt cgaaagagga aatcgagtac
    27001 atcgtcacga actatacgaa tggaaagatt ccagattatc aagtcagtgc attattgatg
    27061 gcaatttttt atcaagacat gacaaatgaa gaaatcacga acttaacatt ggcgattgct
    27121 aattctggtg atgtcatcga tttgagttct cttgaaggaa taaaggtaga taagcattcg
    27181 acaggtggcg ttggtgacac gaccacattg attttagccc ccctagtagc tagtgtcgga
    27241 gtgacagtgg ctaaaatgtc tggacgcggt ctaggttaca caggtggtac actagacaag
    27301 ctagaagcaa ttcccggatt tcagatcgag ctttcggatg aagaatttgt acgcattgtt
    27361 aatgaaagta aagtagcggt aattggtcaa tcaggaaact tggcaccggc ggacaaaaaa
    27421 ttgtatgcct tgcgtgacgt cacagcgacc gttgattctc ttccgctgat tgccagttcg
    27481 attatgagta aaaaaatcgc ggcaggagca gatgcaatcg ttttggatgt gaccactgga
    27541 gacggtgctt tcatgaagaa catcgaagat gcaagacgtc tggcaaagac catgacgagc
    27601 attgggaaac tggctaaccg agaaacagtg gcggttatct cagatatgtc agaacctctt
    27661 ggcgaagcta tcggaaatag tctagaagtt gtcgaggcaa tcgaaacatt acaaggaaat
    27721 ggtccagaag atctagtaga aatgtgctac gccttaggaa gccaaatggt tgttcttgct
    27781 ggcaaagcta agacaaccga tgaagcaaga acgttgcttc aagaagctct ggaatcaggt
    27841 aaagcgttag caaaattcaa agaaatgatc caaaatcaag ggggagaccc agcgatcgtg
    27901 gaacatccag aacgaatttt gactgcacgc tacacaatgg agcttcctgc taaacaaagc
    27961 ggagttgtgt caaaaatcgt ggcaaatgaa ttaggaattg ctgcaatgat gctaggtgct
    28021 gggcgtaaaa ccaaagaaga agatattgat cacgctgttg gattgaaact gcataaaaaa
    28081 attggtgaca ctgtgacaaa aggtgagtca ctattgacga tctatagtaa cgacgaagaa
    28141 atcacttctg tcattgaatt attatataaa aatattgaaa ttggtgaatc ggcaatgaag
    28201 ccaacgttga ttcatgacat catcacagaa taaaggaaaa aagcggactt taccgtttta
    28261 aagaaaaggg gaaaagaaat ggaactaaac cgaatgatcg accatactat tttgaaagca
    28321 gacgcatcta aagaagctgt gatgcaaatt atcgaagaag caaaaaaata ccatttttat
    28381 tctgtctgca tcaatccagc atgggttgcg ctagcgaaag aacaattaca aggtgagcca
    28441 gtagccgtat gtacagtaat cgggtttcct ctaggagcaa acacacccga gacaaaagca
    28501 tttgaaacaa cagatgccat caataacggt gcagatgaag tcgatatggt catcaatatc
    28561 ggtgctttga aatcaaagga tgatcaacaa gtccaaaaag atatcgaagc agttgttgaa
    28621 gcagcaaaag atcgtgcgct tgtcaaagtt attattgaaa catcgttatt agatagagaa
    28681 gaaatcatcc gagcttgcga aatagcaaaa gctgcaggcg ctgattttgt caaaacatca
    28741 actggtttct caacaggcgg agcaaaggta gaggatgtcc gtttgatgcg tgaaactgta
    28801 ggaccagaaa tgggtgtcaa agcttccggc ggtatccata acgaagaaga agcaatggca
    28861 atgatcgaag ctggtgctac aagaatcgga acaagcgcag gagtagcaat cgtatctggt
    28921 tcaactggtg aaggctatta attttttcaa aggagaagct catggcagaa ctcaaacaag
    28981 aatggatcaa cacagctatt gaagcgttag ataaagccta tgttccttat tcccattttc
    29041 cggtaggcgc ttgtctcgta acggaatcag gcaagattta tcaaggcatc aacattgaga
    29101 atgcatcatt tggattaacg aattgtgccg agcgcacagc ttttttcaaa gcagtatctg
    29161 aaggagaaaa aacatttacg catctagtcg tagcggggca cacccccgat cctatctctc
    29221 cttgtggtgc atgtcgacaa gtaatggcag aattctgttc ccctgatatg ccggttacgc
    29281 tagtaggaga caatggtgtg acgaaggcaa cgaccgttcg tgcactgctg ccttatgcat
    29341 ttactgaaaa agatctataa ctcatgttca ttcagtcagc tgactgttga aaaataaaac
    29401 aattatttta ggaggcttta cagaaatgaa aaaagcaaaa ttatttggtt taggtgctgt
    29461 cgcactagca gcagggttat ttttaggtgc atgcggcaac aacggctcta ctgattcatc
    29521 cggtggcaaa agctcatcag acacaacaac tgcagcattg atcacagaca caggtggtgt
    29581 agacgaccgt tcattcaacc agtcagcttg ggaaggacta gaaaaatggg ggaaagatca
    29641 aggactttca cgaggaaatg atggcttcca atatttccaa tcttcaaatg aatcagatta
    29701 catcccaaat attgaccaag cattgaatgc tggattcaaa acgatttttg gtattggtta
    29761 taaactaaaa ccagcgatcc aagaacaagc aacaaacaat acaggtacga actttgttat
    29821 tatcgatgat gtcatcgatg gattagataa cgttgtatct gcaactttca aagacaacga
    29881 agcttcttat cttgcaggtg ttgcagcagc ttatacgact gaaacaaacg tagtcggctt
    29941 tatcggcggt gtaaaaggtg aagtaatcga tcgttttgat gctggattca aagccggtgt
    30001 tgatgcaggt gcgaaagaat taggaaaaga aatcaaagta ttgaatcaat atgctggtga
    30061 cttctctgct ccagataaag gacgttcaat tgctcaaggt atgtatgcac aaaacgcaga
    30121 tatcatcttc catgcttcag gcggtacagg taacggtgta ttccaagaag caaaatcatt
    30181 gaacgaatca ggcgacaaaa aagtttgggt tatcggtgtt gaccgcgacc aatcagacga
    30241 aggcgaatac acattaaacg gcgaaaagaa aaacttcaca ttgacatcta cactgaaagc
    30301 agttggaaca gtagtagaag atttggcaca aaaatcagcg gacggtaaat tccctggcgg
    30361 cgaacacact gtttatggat tgaaagaaga cggtgttggt ctaacagaag gacaactttc
    30421 tgacgaagcg aaaaaagcag ttgatgaagc aaaagaaaaa atcatttcag gtgacgtaaa
    30481 agttccagaa actcctgaag aaaactaaaa ccatttctat agccttgtta gacacatgtt
    30541 tgacaaggct atggtttgat tagaacaaga attgttcatt tatccaagct gccttgtgac
    30601 agtttggata agggaacaac tccctgaagt aatgtttgtt tcaaaagaag aacgctcact
    30661 aagcgtgaat cttagtcaat cgttgcccta gatagaaatc gttaggatgt gaaaaaaagg
    30721 tggttcaaga aaatattgtc atagaaatgc agaatattac caaagaattt ggaacattca
    30781 aggcaaatga caacatcaat ttacaagtaa aggcaggaga aattcatgcg ttgcttggag
    30841 aaaacggtgc tggcaaatct acattgatga acgtgctttc cggattatta gagccgacat
    30901 cagggaaaat tttgatgcgt gggaaagaag taaagatcac aagtccgacc aaagccaacc
    30961 aattagggat tgggatggtc catcagcact ttatgcttgt tgatgccttt actgtaacag
    31021 aaaacatcgt gttgggaagc gagcctagtc gcgcagggat gcttgaccat aaaaaagcac
    31081 gaaaagagat ccaaaaagtt tctgaacagt atggattgtc agtcaaccca gatgcttacg
    31141 ttcgtgatat ttcagttgga atggaacaac gggtagaaat tttaaaaaca ctttaccgag
    31201 gagcagatgt actgattttt gatgagccga cagctgtatt gacccctcaa gaaattgatg
    31261 aattaatcgt gatcatgaag gaattagtca aagaaggcaa gtcgatcatt ttgattacgc
    31321 ataagttaga tgaaatcaaa gcagtagctg accgctgtac agttatccgc cgtggaaaag
    31381 gaatcggtac agtcaacgtt aaagacgtaa cctcacaaca attagccgat atgatggttg
    31441 gaagaacggt ttcattcaaa acgatgaaaa aagaagcgaa gcctcaagaa gtcgttttgt
    31501 ctattgaaaa tctagtggtg aaagaaaatc gtggattaga agccgtgaaa aacttgaact
    31561 tagaggttcg tgctggcgaa gtacttggta tcgctggaat cgatggaaac gggcagtcgg
    31621 agttgatcca agctttgact ggtttgcgaa aggcagaaag cggacatatc aagctaaaag
    31681 gggaagacat cactaataaa aaaccccgaa aaatcactga acatggtgta ggacacgtgc
    31741 cagaagaccg tcataaatac gggttagtcc tagatatgac attatctgaa aatatcgcac
    31801 tacaaaccta tcatcaaaaa ccttacagta aaaacggcat gctgaattat tcagtaatga
    31861 atgaacatgc cagagaattg atcgaagaat atgatgttcg aacaacgaat gaacttgttc
    31921 ccgcaaaagc tttatcaggc ggaaatcagc aaaaagcaat tatcgctcgt gaagtcgacc
    31981 gagatcctga tctgttgatt gttgcaaatc caactcgtgg actggatgta ggtgcgatcg
    32041 aatttattca taaacgtctg atcgaacaaa gggacaaata caaagcagtg ttactgatca
    32101 gtttcgaatt agaagaaatt ttaaatgttt cggatcgtat tgctgttatc catgaaggag
    32161 aaattgtcgg tatcgttgat ccgaaagaaa catctgaaaa tgaattaggt ctattgatgg
    32221 cgggctatac cttagaagaa gcacgaaaag agttagaaaa gggggctggc gcacatgaat
    32281 gatcgcagcg aaaaattccg taatttatta gtgcctgtac tttcagttgt tttaggattg
    32341 atcttaggcg cgatattgat ggctgctttt ggttttcagc ccatccaagg ttattcttct
    32401 atgctagatg cagcccttgg ttcgcaaaga gggataggtg aaacgttaag gcaagcaacg
    32461 ccgttgattt ttacagcatt aggtttttct gtagctaact cagctgggtt tttcaatatt
    32521 gggctttctg gacaagcact ttgcgggtgg atcgtcagtg tctgggtggc acttgcgttt
    32581 ccagatctgc caaaagttgt tttgcttccg ttatgcgtga tcttaggtgc cttagctggt
    32641 gcgatggcag cggctgttcc aggtttactt cgagcatttt ttggaacaag tgaagtgatc
    32701 gtaacaatca tgatgaacta tatcttatta tacgtaagca catttgcttt acatgaagtg
    32761 atgcctgaaa gctatcgctc aagtttggac tcttccaata tgatcagtca aaatgcctca
    32821 ctgcggttac catggttaac acaagctttt ggcggctctc gcgtaaactc aggattattt
    32881 ttagcaatca tcgcgcttat tttcgtttgg ctgctgatga agaaaacgac tttaggattt
    32941 gaaatccgtt ctgttggatt gaatcctttt gcttctgagt atgcaggaat gagtagtaaa
    33001 cgtacgatcg ttttgtcgat ggtcatttct ggcgctttgg cagggcttgg cggtgtggtt
    33061 gaaggattag gaacgtatca aaacttcttt gttcaaacga cttcgctatc tattggattt
    33121 gacggaatgg ctgtttcctt gcttggttct ggatcagcaa tcggtattct tttatcagcg
    33181 atcttgttca gtattttgaa gatcggtgga cttggcatgc agacaggagc aggtgttccg
    33241 tttgagatcg tcaatgtatc gattgctttg attatcttct ttgtcgggat caacttcctg
    33301 attcgtttcg tcatggctaa agtcttccaa gggaaaaaac aagaagagat cgttgcgaca
    33361 atagaatcga aaccaacgaa tcaaaaccat gaagggggcg aactataatg tcgactatcg
    33421 aattaattgc cttgatcctt acttctacac tggtttattc aacaccgcta attctaacgt
    33481 cactaggcgg aactttttct gaacgaagcg ggatcgtaaa cgtagggcta gagggaatca
    33541 tggtcatggg tgcttttagt tccatcgttt tcaacttgac gatgagtcca tcacttggtt
    33601 ctatgacacc atggatcgct attttagtgg gtggcgtcgt aggtatccta ttttctctga
    33661 ttcacgcagt agcaacagtc agtttgcgtg ctgaccatat tatcagcggg acagtaatta
    33721 atctgatggc acctgcttta ggtgttttct tgatcaaagc atggtatggt aaaggtcaaa
    33781 ctgataacat cacgcagaat ctggggtatt tttctttccc aggattagca gatattccgg
    33841 tcattggacc aattttcttt aaaaatacat tcttacctgc ttattgtgct attttgattg
    33901 ctgtcctagc ttgggtgatc atcttcaaga cgaaattcgg cttgcgcctc cgttcagttg
    33961 gtgaaaatcc tcaagctgcc gacacattag gtatcaatgt atatgctatg cgttattcag
    34021 gcgtactgat ttctggcttg ttaggcggta tgggcggtgc tgtttttgct cagtcgattt
    34081 ccggtaactt ttcagctggt acgatcgttg gacaagggtt catctccatg gctgctatga
    34141 tctttggtaa gtggaatcct ttaggggcaa tgggtgcctc attgttcttt ggttttgctc
    34201 aaagcttgag tatcattggc gcacaattac cagttatttc ttcgattccg ccagtattgc
    34261 tgcaaattgc tccatatttg ctgacaatca ttgtgctggt tgttttctta gggaaagctt
    34321 ctggtccaaa agcaaacggg aagaactata tcaaatcaaa ataatctttt agcgaataaa
    34381 aagggtgggt tacgggaagt gtttttcgtc tcgccctttt tgttttaaag gcaataaaaa
    34441 taaaaagaaa gaaggaataa tcatgtttaa acgcgtacat ctgatcgtca tggattcagt
    34501 aggaattgga gaagcaccag atgccgataa gttcggtgat gttggttctg atacattagg
    34561 acacattgcg aaagaagcag gattgaacgt tccacattta gagcagcttg gtttaggaac
    34621 gatccgtcct cttgaaggtg tggaatcagt gaaagatcat caaggctatg cgacgaaatt
    34681 agaagaagtt tctgtaggga aagatacgat gacaggccac tgggaaatca tgggattgaa
    34741 tatcaaaact ccatttcgtg tgtttcctaa tggattccct gatgatctga tcaaacaaat
    34801 cgaagaattt tctggccgta aagtcgtatg taacaaacct tatagcggaa cagctgttat
    34861 tgacgattac ggtgaacacc aaatgaaaac aggcgattta attgtatata cttctgccga
    34921 tcctgtcctt cagatcgcgg cacatgaaga aatcattcct ttagaagaat tatatcggat
    34981 ttgccaattc gttcgtgata taacaaaaga tgatccgtat atgattggcc gaatcattgc
    35041 acgtccgtac gtgggtgaac caggagactt cacacgaaca agcaatcgcc atgattatgc
    35101 gttgaatcca ttcggacaca cagtccttga ttctttgaaa gaagcaggaa aggacgtgat
    35161 tgctgttgga aagatcaacg atattttcaa cggacaagga atcactgaat ctgtccgcac
    35221 gaaaagcaat atggatggcg ttgaccagct gctgaaagtt atgaaaaacg atttttcagg
    35281 aatcagcttt accaatttag tagattttga tgcattatac ggtcatcgtc gggatgtagt
    35341 cggctatgcg catgcgattg aagaatttga cttacgaatt ccagaattgc ttgaagcgat
    35401 ggaagaagac gacttgctaa tgattacagc cgatcacgga aacgatccga cgtttactgg
    35461 taccgatcat acgcgagaat atgtaccgtt attggtttac agtaaaaaaa tgaaagaaca
    35521 aggggcattg cctcaaggat attattcaga tatttcagca acgattgctg agaactttag
    35581 tgtttcttcg actgaaaatg gcgaaagctt cttgaaatta ttaaaataat ctttttaaat
    35641 aggagaaagc aaatgaccaa gttaagcgag atgttacaag aaacgaccca gtttatcctt
    35701 gataaaggag taaaagaaat tgattttggt ttgattctag gttcaggatt aggtgaatta
    35761 gcagatgaaa tcgaagatgc tgtaatgatt tcttatgatg agatcccgtt ctttcctgtt
    35821 tcgacagtag ttgggcatgc aggaaagcta gtttatgggt ctctggcagg caagaaagtg
    35881 ttagccatgc aagggagatt ccactactat gaaggtcatt ccatgcaaac agtgacctat
    35941 ccagtacgtg tgatggccgg actaggggcc cattcagtca ttgtgactaa tgcatgtggt
    36001 ggtgtcaacg aatcatttgt accaggagat ttgatgctga ttaccgatca tatcaatttt
    36061 actggtgaaa atcctttgat cggtccgaat gaagatgcaa tgggccctag atttccagat
    36121 atgagtcaag cttatacgcc tgactatcaa gcaacagcaa aagcagcagc agaaaaacta
    36181 ggtttggatc ttaaagaagg cgtatatatg ggctattctg gaccaactta tgaaacgcct
    36241 gcggagatcc gaatgtctcg gacaatagga gccgatgcag tagggatgtc gactgttcca
    36301 gaagtcatcg tagcagctca cagcggatta aaagtgttag gaatctcttg tattaccaac
    36361 ttagcagcag gtatgcaagc gaatctgagc catgaagaag ttgtagaaac aactcagaga
    36421 gtcaaacaat cttttaaagc attggttaaa gaaacattga cattattgta ataggaggaa
    36481 caataaaatg agtgtgcata ttgaagcgaa agaaggcgag atcgccgata agattttact
    36541 tccgggagat cctttgcgag ctaaatatat tgcggagact tttttggaag atccagtttg
    36601 ttacaatcag gtacgcggta tgttaggctt taccggcaaa tataaaggag aacgtatttc
    36661 tgttcaagga acaggaatgg gaatgccatc agccaccatc tatgcccatg aattgatcca
    36721 gtcgtatggt gtaaagaaat tgattcgagt aggtacatgc ggtgcattgt caaaagacgt
    36781 ccatgttcgt gatttagtac tagcacaagg tgcagcgacc agttcttcga tgatcgaaaa
    36841 aaatttccaa gcctttcatt ttcctccaat cagtgatttc aatctattac tgaaagcata
    36901 tgagatagct aaagaaaagg gctatacggt tcatgtagga aatgttcttt cggaagattc
    36961 tttctacaaa gatgatttga cagagacgtt ccaattagct gaacttggcg ttttaggagt
    37021 ggaaatggaa gcagcggctc tttattactt aggcgcgaaa taccatgtgc agacattaag
    37081 tttgatgacc gttagcgacc atttgatcac cggtgaagaa acaacagctg cagaacgtca
    37141 atctacgttc aatgaaatga tcgaagtagg attggaaaca gcgatagcag aataagaagg
    37201 aaatgaaaaa gctgccctgc attaagtaat aagaacatcc aagcaaaaat agctcctcat
    37261 gtttttgact tggctggact tattattgca aatgtaagct tttgaacacc gtttaccaag
    37321 aggttgtgaa tctgccgttt aactctgagt cacaaggaac aatttcaaaa aacagctttt
    37381 catgtttgat gaatattgtg acttgtgacc gagaagttgg caggagaaaa ccgtttatac
    37441 gaaaaaaggg actgtgacaa atcgtgtcac agtccctttt ttatagtgtt ttttataggt
    37501 agtatttttt agcaactgtt aagtcatcat ttaattcata aacaagtggt tgacctgttg
    37561 gaatttcaag atccatgatg tcttcgtcag agataccttc gatatgttta gctagggcgc
    37621 gtaatgagtt accatgtgca gctactaaaa cagttttgtt gtctagtaat gctggagcaa
    37681 tttcatcttg ccagaatggc aaagcgcgtt ctaatgtcac tttcaagttt tctccaccag
    37741 gaatatcgcg tttgtctaac attgcgtaac gacggtcatt tgctgcagaa ccttcgtcag
    37801 tttcttccat taatggagga agagtatcgt aagaacgacg ccagatgtgc acttgttcgt
    37861 cgccgtattt ttcagctgtt tcttttttgt tcaaaccttg taatttacca tagtgacgtt
    37921 cgtttaagcg ccatgatttg atttgtggta cccaaagttg atctgaatat tctaagatca
    37981 agttacatgt tttgattgca cgagttaaaa cagaagtgta agcaacatca aattcgattc
    38041 cagcttcttt gattttgcgt ccgccttctt ttgcttcttc gattccttct ggtgctagat
    38101 ttacatcagc ccaaccagta aattggttca atgcattcca ttcactaaga ccgtgacgag
    38161 aaaaaactaa ttttggcatg tttagctctc cttttaagat aggtttatat ttctgaaatt
    38221 ttcagttctg ttttattgta caattttttg gaagagattt ccatcgaaaa attagataag
    38281 attctatgag aaaacaagta gagaatataa aaaaacgaac agtgcccacg caactgttcg
    38341 tttttaggta ttagatgcat aattgctcga tttctttttc aggtaaattg atatatttat
    38401 aacatgttcc aactgaaaca ccgcattttg aagaaataaa ttggatcgtt tctttttttt
    38461 cataatagag acgtcggatt tttttgatcg tttttgcatc gatttttggt cttccgccga
    38521 tttttccttt tttacgagct tcatctaatc caactaatgt acgttctttg atcaatgcgc
    38581 actccatgtt tgctaggttt tccattaatt ggaaatagat ttttcccatt tcgcgcgtat
    38641 cgattccttc atcaagacta atcaagtgca gcccgcgatc tttgaataat tgcgtgagtt
    38701 ctgttaattg ccgcgtagat ttgcctaatc gatgaagttg gcaaatgact agtgcatcgc
    38761 cttgttgcat gtcagcgatc actgactcca aatgaacagc agtagaatca ttttgttcca
    38821 cttcatatgt ctcatggaaa atttcttgac aaccaaagtc agataattga tcaacctgag
    38881 ttgttaaatc aacgtcattt atggttgtgc gtgcataacc aataattttc atggtgattc
    38941 ctttctagca gtgattttct aactggatat aacagtaaaa atgtagcata aagtacgtca
    39001 aaaagatagt tttttcgcaa attttccgct gtcttttttt attggatgat caagcagttt
    39061 ttctttattt acgacggatt gcgtcaagaa tctcaacgcc tttttctgag ccgacaacta
    39121 ctttagaaac catgtttagg aaaagcccat gttctactac cccaacaagt tcatctaaat
    39181 aggtagctaa gctttctggc tgttcgatga cttctagatg cagatcaatg atgtaatgac
    39241 caccatctgt ggttaagact tctccgtttt cgtctgtacg caagacgggt tggaatcttt
    39301 tttcttcaaa aatatgaagt agctgttggg agccataagg gatcacttca actgggagtg
    39361 ggaacttccc aagtttatcg actaatttag aagaatcaac gatccaaatc gtttcttttg
    39421 agtacgtagc gactattttc tcgaaaagca aagcagcgcc gccgcctttg atcccttgaa
    39481 aatcagcact gatttcatca gcaccgtcta ttgtcaaatc gactacgggg acttcatcaa
    39541 tactctttaa cggtattcct aatttttccg cttgttcttt tgtcgcattt gaagtagtaa
    39601 ctcctgtgat acgtaaacct tcttcacgca tacggcgacc aatctcttct accatataat
    39661 aggcggttga accggtcccg agacctacga tcatcccgtc ctttacgaat ttcgcggctt
    39721 caatgccagc taattgtttt aaattcatct ttgcgtccac ctttttttag tttgagcatc
    39781 gtgctttcct cactatttta gcgtgattta cggtaaaaag ataccattct tttttattcc
    39841 aataaagctt tttcaaaaaa aattgcatct cttgttgaca tgttttttca ttcgtgatat
    39901 tctaacaaag gtgctttatc tacaggtttc tgtgaagaaa cgtgctgact gtttatcaaa
    39961 gcatatttga taaggatgca gacattgcat ttatttttta tcacaaaaaa agaaccacct
    40021 ggatgtgtgg aactagacgc aaatcgtggg aaggaggaaa caaggaatgc ctacaattaa
    40081 ccaattagta cgtaaacctc gtaaatcaaa ggtggaaaaa tctaattcac ctgctttgaa
    40141 caaaggatat aacagcttta agaaaactca aactaacgta aactcacctc aaaaacgtgg
    40201 ggtagcaact cgtgtgggta caatgacacc taaaaaaccg aactcagctt tacgtaaata
    40261 tgcacgtgtt cgtttgtcaa acttaattga agttactgct tatatcccag ggattggtca
    40321 taacttacaa gaacacagtg ttgtattatt acgcggtggt cgtgtaaaag acttaccagg
    40381 ggtacgttac catatcgttc gcggtgcttt agatactgct ggtgttaacg accgtaaaca
    40441 aagccgttct aaatacggaa ctaaaaaacc taaagcttaa ttttaattat taaacaaatg
    40501 aaacttgctt ctactatata gaagtaatta ctatgaacaa tatttcggaa ggaggagtta
    40561 cggatgccac gtaaaggtcc tgttgcaaaa cgtgatgttt taccagatcc tatttataac
    40621 tcaaaattag taactcgctt gatcaaccgt gtaatggttg acggaaaacg cgggattgca
    40681 gctaacatta tctataatgc ctttgacttg atcaaagaat ctacaggtaa cgatccatta
    40741 gaagtgtttg aacaagcaat gaaaaacgtt caacctgttc ttgaagttaa agcacgtcgt
    40801 gttgggggtt caaactacca agtaccagtt gaagttcgcc ctgaacgccg cgttactcta
    40861 ggtcttcgtt gggtagtaaa ctacgctcgc ttgcgcggtg aacacacaat ggaagaacgc
    40921 ttagcaaaag aaatcatgga tgctgcaaac aacacaggtg cttctgttaa aaaacgtgaa
    40981 gacactcata aaatggctga tgccaaccgt gcgtttgctc actatcgctg gtaagattct
    41041 ctctgtttgg tcggctttta taagtcgacc tcagatagtg tccttatttt tagcaactag
    41101 atagtaaaga gaggagaaac aaggagaatg accagagaat tttctttaca aaacactcgt
    41161 aatatcggta tcatggccca catcgatgct ggtaaaacga ctgctactga acgtatcttg
    41221 tactatactg gtaaaatcca taaaattggt gaaactcatg aaggagcttc acaaatggac
    41281 tggatggaac aagaacaaga acgtggtatt acgatcactt ctgctgctac tacagcacaa
    41341 tggaagggtc accgaatcaa catcatcgac acaccaggac acgtagactt cacagttgaa
    41401 gttgaacgtt cattgcgtgt acttgatggt gctgtaactg ttcttgatgc acaatcaggt
    41461 gttgaacctc aaactgaaac agtttggcgt caagcaacaa cttatggtgt acctcgtatc
    41521 gtatttgcaa acaaaatgga caagatcggt gctgacttct tatattcagt atcaacttta
    41581 catgaccgtt tgcaagcaaa cgctcaccca atccaattac caattggtgc ggaagacgac
    41641 ttcacaggaa ttatcgacct tgtaacaatg aaggctgaaa tgtatacaaa cgatcttgga
    41701 acagagatcg aagaaacaga aattcctgaa gaataccgcg aattagctga agaatggcgc
    41761 gaaaaattgg ttgaagctgt agctgaaact gatgaagaac ttactttgaa atacttagaa
    41821 ggtgaagaaa tcactgaagc tgagttaaaa gaaggtatcc gccgcgcaac agttaacgta
    41881 gaattctacc cagtactatg tggttcagca tttaagaaca aaggggttca attactattg
    41941 gacgctgttc ttgattactt gccatcaccg ttagatatcc cagctatcaa agggattgac
    42001 cctaaaactg atgaagaagt agaacgtcct gcagacgaca gcgctccttt ctcagcttta
    42061 gcatttaaag ttatgactga cccattcgta ggtcgtttaa ctttcttccg tgtgtactct
    42121 ggtgttttac aatcaggttc atacgtacaa aacgcaacaa aaggcaaacg tgaacgtgtt
    42181 ggtcgtatcc tacagatgca tgccaactct cgttcagaaa tctctgaagt ttacgctgga
    42241 gatatcgctg ctgctgttgg tttgaaagac acaactactg gggacacact atgtgatgaa
    42301 aagagtctag ttattcttga atccatggaa ttcccagaac cagttatcca agtcgctatt
    42361 gaacctaaat caaaagctga ccaagataaa atgggtgtgg ctttacaaaa actatctgaa
    42421 gaagatccta ctttccgtgc tgaaacaaac gtggaaacag gcgaaacaat catcgctggt
    42481 atgggtgaac ttcacttaga tatcatcgtt gaccgtatgc gtcgtgaatt caaagttgaa
    42541 gctaacgtag gtgcgcctca agtatcttac cgtgaaactt tccgtgctgg cactcaagcc
    42601 gaaggtaagt ttgtacgtca gtctggtggt aaaggtcaat acggtcacgt atggattgaa
    42661 tttacaccaa atgaagaagg tgctggtttc gaatttgaaa atgcgatcgt cggtggggtt
    42721 gttcctcgtg aatacattcc agctgttgaa actggtttga aagatgctat ggaaaatggt
    42781 gtcttagctg gctatccatt agtagatatc aaagctaaac tttacgatgg ttcataccat
    42841 gatgtcgatt caaatgaaac tgccttccgt gttgctgctt ctatggcatt acgtgcagca
    42901 gctaagaaag ctaatccagt aatccttgaa ccaatcatgg ctgtagaagt tgttatccct
    42961 gaagattatt taggtgatgt tatgggtcac gtaactgctc gtcgtggacg tgttgaaggt
    43021 atggaagctc gcgctggcgg ccaacaagtt gttcgtgcga tggttccact tgctgaaatg
    43081 tttggttatg ctacaactct tcgttctgct actcaaggtc gtggtacatt tacaatgaca
    43141 tttgaccact acgaagatgt accaaaatca gtacaagaag aaatcattaa gaaaaacggc
    43201 ggaaaagctg aataatttct taaaaccgga tagtcctgca aagagattat ccaaagagac
    43261 tatattttta atatagtttc gtgtaaaata attatcgatg atatgggcat gtggtgtacc
    43321 ttgtgtacat catataccta tcagacaaat aaaaaatata ttgtattttt aggaggacat
    43381 tttaaaatgg caaaagaaaa atttgaccgt tctaaaccac acgttaacat tggtactatc
    43441 ggacacgttg accatggtaa aactacatta acagctgcaa tcacaactgt actatctaag
    43501 aaaaacggcg gccaagctat ggcttacgat caaatcgatg gtgctccaga agaacgcgaa
    43561 cgcggaatca caatctcaac agctcacgtt gagtatgaaa cagatacacg ccactacgct
    43621 cacgttgact gcccaggaca cgcggattac gttaaaaaca tgatcactgg tgctgctcaa
    43681 atggacggag ctatcttggt agtttctgct gctgacggcc caatgcctca aactcgtgaa
    43741 cacatcctat tgtctcgtca agttggtgtt ccttacatcg ttgtattctt gaacaaagta
    43801 gacatggttg atgacgaaga attactagaa ttagttgaaa tggaagttcg tgacctatta
    43861 acagaatacg aattccctgg tgacgatgtt cctgtagttg ctggatcagc tttgaaagct
    43921 ctagaaggcg acgcttcata cgaagaaaaa attcttgaat taatggctgc agttgacgaa
    43981 tacatcccaa ctccagaacg tgacaacgac aaaccattca tgatgccagt tgaagacgtg
    44041 ttctcaatta ctggacgtgg tactgttgct acaggtcgtg ttgaacgtgg acaagttcgc
    44101 gttggtgacg aagttgaagt tgttggtatt gctgaagaaa cttcaaaaac aacagttact
    44161 ggtgttgaaa tgttccgtaa attgttagac tacgctgaag ctggagacaa cattggtgct
    44221 ttactacgtg gtgttgcacg tgaagacatc caacgtggac aagttttagc taaaccaggt
    44281 acaatcacac ctcatacaaa attctctgca gaagtatacg tgttgacaaa agaagaaggt
    44341 ggacgtcata ctccattctt cactaactac cgtccacaat tctacttccg tacaactgac
    44401 gtaacaggtg ttgttgaatt accagaagga actgaaatgg ttatgcctgg cgacaacgta
    44461 acaatggaag ttgaattaat ccacccaatc gctatcgaaa acggtactaa attctcaatc
    44521 cgtgaaggcg gacgtacagt tggtgccggt gtcgttacag aaatcaaagc ttaattcact
    44581 taagttttaa agtaaagcaa catttattcg gacgtaatcg ctcggaacga aggtcttagg
    44641 atctttgttc cgagcttttt tatttattgc aggatcagga aaaaagacag gagtattata
    44701 aatagaagaa acacgaaata aaagagtcag tattttctaa atgaaacttt atgaaaacaa
    44761 aatgtttttt acaagaaaaa gccttgcttt gtgagtttat atatattata atgacaaagg
    44821 tgcgtttact ttagtgaatt gcacagacgt aatcagaatg atttcgtcgg ctaagaaacg
    44881 agaggttgcg acacgcccgg acgctttgcc acgaacgagc gtgacggaaa ttttcgtgga
    44941 gctatgtcta cttttcaaaa taggcgaagg agggaacaag atggcaaaac aaaaaattcg
    45001 tatccgttta aaagcgtatg aacaccgtat tttagatcaa tcagcggata aaatcgtgga
    45061 aactgcaaaa agaactggag ctagcgtgtc tggtccaatt ccattaccaa ctgaacgcag
    45121 tctttacaca atcatccgtg cgactcataa atacaaagat tcacgcgaac aattcgaaat
    45181 gcgtacacac aaacgtctta tcgacattgt gaacccaaca ccaaaaactg ttgatgcttt
    45241 gatgaagcta gacttaccat ctggtgtaaa catcgaaatc aaattataaa actaaaacaa
    45301 aaataatgga ggtgtactca tgaccaaagg aatcttaggg aaaaaagtgg gaatgacaca
    45361 aatcttcact gaatctggtg aattaattcc agtaactgtt gtagaagcta ctccaaacgt
    45421 agtactacaa gtgaaaacaa tggaaacgga tggctacgaa gctattcaag ttggttacca
    45481 agatatgcgt gaagttttat caaacaaacc tgcgaaaggt catgttgcaa aagcaaacac
    45541 ggctcctaag cgcttcattc gtgaattcaa aaatgttgag ctaggagaat atgaagtagg
    45601 aaaagaaatt acagtagatg ttttccaagc aggagacatt attgatgtaa caggtactac
    45661 gaaaggtaaa ggattccaag gggttatcaa acgccacgga caaagccgcg gaccaatggc
    45721 tcacggttct cgttaccatc gtcgtcctgg gtcaatgggt ccagttgcac ctaaccgtgt
    45781 atttaaaaac aaacgtcttg ctggccgtat gggtggcaac cgcgtaacta tccaaaactt
    45841 ggaagttgta cgtgtcgatg cagaaagaaa tgttatcttg atcaaaggta atgttcctgg
    45901 agctaaaaaa tctttaatta ctatcaaatc agctgtgaaa gctaaataat tgtaggaaga
    45961 aaggaggaac taaggaatgc cgaatgtagc attattcaaa caagatggaa gccaaaacgg
    46021 tgaaatcaca cttaacgaag aaatcttcgg aattgaacct aatgaaagtg ttgtttacga
    46081 tgcaatcgta atgcaacgtg cgtcattaag acaaggaaca cacgcggtta aaaaccgtag
    46141 cgctgttcgc ggcggcggac gtaaaccatg gcgtcaaaaa ggaacaggtc gtgcacgtca
    46201 aggatctatc cgctcaccac aatggcgtgg aggtggcgta gtctttggac caacaccacg
    46261 ttcttacagc tacaaacttc ctaaaaaagt tcgtcgttta gcaatgaaat ctgtattgtc
    46321 agaaaaagtt gctgaaaaca acttggtagc aatcgaaggc ttgaacttcg acgcaccaaa
    46381 aacaaaagaa ttcaaacaag ttcttgctaa cttatctatc gactctaaag tattggttgt
    46441 tctagaaaaa ggtaacgact ttgctgcttt atcagcacgt aacttaccaa acgtttctgt
    46501 agtaacttct gataatgtga gtgtgctaga cgttgtatca aatacaaaag tgttagcaac
    46561 acaaactgct cttactcaaa ttgaggaggt gcttgcataa tgaacttact agacgtaatc
    46621 aaacgcccag tgatcactga aaaatcaatg cttgccatgg atgacaagaa atacactttt
    46681 gaagtggaca ctcgcgcaaa caaaacttta gtaaaacaag cggtagaagc tgcttttgac
    46741 gttaaagtca aaaacgtgaa catcgtgaac gtacgtgcga aattcaaacg tatgggcaaa
    46801 tatgcaggat atacaaaaaa acgtcgcaaa gcgatcgtta cattgactga agattcaaaa
    46861 gaaatccaat tattcgaagc tgctgaataa gcactaatag ataactcatt aaattaggag
    46921 ggaaaaacgt ggcgattaaa aagtacaaac ctacctcaaa tggtcgtcgt aacatgacag
    46981 gttctgattt tgctgaaatc acaacatcaa cacctgaaaa atcattgtta caaccattga
    47041 aaaaccatgc tggacgtaac aacaacggcc gcatcactgt acgtcatcaa ggtggcggac
    47101 acaaacgcca atatcgcgtg atcgacttca aacgtaacaa agataacgtt gttgcaactg
    47161 ttcaaacgat cgaatatgat ccaaaccgtt cagctaacat cgcgttagta cactatgaag
    47221 atggagtgaa agcttacatc ttagcaccta aaggactaga agtgggtatg aaacttgttt
    47281 caggtccaga agcagatatc aaagtcggaa atgctcttcc attagaaaac attccagttg
    47341 gtactgttat ccacaacatt gaaatgaaac ctggtaaagg tggacaattg atccgttctg
    47401 ctggtacaag tgctcaagta cttggtaaag aaggcaaata cgtattgatc cgcttgaact
    47461 ctggtgaagt tcgtatgatc ttagctgcat gccgtgctac aatcggttct gtaggtaacg
    47521 aacaacacga attaatcaac atcggtaaag ctggacgctc tcgttggatg cgtaaacgcc
    47581 caactgtacg tggtagcgta atgaacccta atgatcaccc acacggtggt ggtgaaggta
    47641 aagctcctat cggacgtaaa gcaccagttt ctccttgggg tcaaccagct cttggttaca
    47701 aaactcgtaa caaaaaagct aaatcagaca aacttattgt tcgtcgtcgc aaaaataaat
    47761 aattactttg accatgtgtc gcacattttg agaggaggtt caccatgggt cgtagtttaa
    47821 agaaaggacc ttttgtcgat gagcatttaa tgaaaaaagt tgaagctcaa gcaggggttg
    47881 aaaagaaaaa agttatcaaa acttggtcac gccgttcaac agttttccca agttttgttg
    47941 gatataccat cgcagtttat gatggacgta aacatgtacc agtttacatc caagaagaca
    48001 tggtaggaca caaattaggt gaatttgcac ctacaagaac ttatcgtgga catgctgctg
    48061 acgataagaa aacgaaacgc taatttgagg ggaggataaa tccaaatggc agaacaaatc
    48121 acatcagcta aagcaactgc aaaaacagtt cgcacttcac ctcgaaaagc ccgtttagta
    48181 attgacctta tcagaggtaa aagtgtcgca gatgcaattt caatcttgaa attcacacca
    48241 aacaaatctg ctggaatcat tgaaaaagta ttgatgtcag cagttgcgaa tgcagaaaat
    48301 aactttgact tagatgttga aaacttggta gtaagcgaag cttttgttaa cgaaggacct
    48361 acaatgaaac gtttccgtcc tcgtgcaaaa ggatcagctt ctccaatcaa caaacgtaca
    48421 agtcatatca cggtagtcgt atcagaaaaa taaggaggga taatcagtgg gtcaaaaagt
    48481 acatccaatt ggaatgcgtg taggcatcat ccgcgactgg gatgctaaat ggtatgctga
    48541 aaaagagtat gctgagttct tacacgaaga tttaagaatc cgtaaattta tttcaactaa
    48601 acttgctgat gctgctgtat caacagttga aatcgaacgc gcaacaggtc gcgtaaacat
    48661 ttcaattcac acagctaaac caggtatggt tattggtaaa ggcggttctg aagtcgaaag
    48721 cctaagaaaa gaattaaaca aattaactgg taaaagaatc catatcaata tcgtggaaat
    48781 caaaaaacca gatctagatg caaaattagt aggtgaagga atcgcacgtc aattagaaaa
    48841 ccgtgttgct ttccgtcgcg ctcaaaaaca agccatccaa cgctcaatgc gtgctggcgc
    48901 tcaagggatc aaaactcaag tatctggtcg tctaaacgga gcagatatcg ctcgttcaga
    48961 aggatactca gaaggaactg ttcctcttca tactttacgt gcggacattg attacgcatg
    49021 ggaagaagca gatacaacat acggaaaact aggagttaaa gtgtggatct atcgtggaga
    49081 aattcttcca actaaaaaaa acactgagaa aggagggaaa taatcatgtt agtacctaaa
    49141 cgtgtaaaac accgtcgtga attccgcgga aaaatgcgcg gggaagctaa aggcggaaaa
    49201 gaagtagcat tcggtgaata cggtttgcaa gctgttgatt cacattggat cacaaaccgc
    49261 caaatcgaag ctgctcgtat cgcaatgact cgttacatga aacgtggtgg gaaagtatgg
    49321 attaaaattt tccctcacaa atcttatact gccaaagcaa ttggggtacg tatgggttct
    49381 ggtaaagggg cacctgaagg atgggttgca ccagtaaaac gtggtaaaat catgtttgaa
    49441 atcgcaggcg ttcctgaaga agtagctcgt gaagcgttac gtctagcttc tcacaaatta
    49501 ccaatgaaaa ctaagatcgt aaaacgtgag gaaatgggtg gtgaatcgaa tgaaggttaa
    49561 agaaatcaga gaattaacca ctgccgaaat gcttgatcaa gaaaaacaat taaaagaaga
    49621 attgtttaat cttagattcc aattagcaac aggtcaatta gaaaacactg cacgtattaa
    49681 agaagtacgt aaatcgattg cacgcatcaa aactgtgttg cgtgaacaag ctaagtaatt
    49741 atggaaggag gccattaagc gtatgactga aggaagaaat caacgcaaag tttatcaagg
    49801 tcgcgtggtt tcagacaaaa tggataaaac aattaccgtt gctgtcgaaa caaagaaaaa
    49861 ccaccctatc tatggcaaac gcatgaacta ttctaagaaa tacaaagtgc atgatgaaaa
    49921 caacacagca aaagttggcg acatcgtgag aattatggaa actcgtccat tatcagctac
    49981 aaaacgtttc cgtttgttgg aagtagtcga agaagcagtt attatctaat aacacgagat
    50041 tttcctatat agattgaatg caaaatctga aaggaggata cacaacgtga tccaagcaga
    50101 aagtcgttta aaagtcgctg ataactcagg cgcacgtgaa attttgacga tcaaagtcct
    50161 tggtggatct ggtcgtaaaa ctgctaacat cggtgatgtg atcgttgcta cggttaaaca
    50221 agcaacgcca ggtggggttg tcaaaaaagg tgacgtcgtt aaagccgtta tcgttcgaac
    50281 aaaatcagga gctcgtcgta cagacggttc atatattaaa tttgatgaaa atgctgcagt
    50341 gattattcgt gatgataaaa gccctcgtgg aacacgtatc tttgggccag ttgcacgtga
    50401 actacgtgaa aacaacttca tgaagatcgt ttcactagca ccagaagttt tataatcttg
    50461 agacacttat caaaggaggt gcgaaacagt tatgtttgtt aaaaaaggcg ataaagttaa
    50521 agttatcact ggaaaagaca aaaacaaaga aggcgttgta ctagcagcgt tcccgaaaaa
    50581 agataaagtt attgtcgaag gtgtaaatgt cgttaaaaaa caccaaaaac cttctcaagc
    50641 tgctcctcaa ggtggaattg ttgagatgga agcgccaatt catgtttcta acgtgatggt
    50701 ggttgactct actggtgtag ctggccgagt tggctacaaa gaagtagacg gcaaaaaagt
    50761 ccgtgtttct aaaaaaaccg gtgaagtttt agataaataa aagtttaagg aaggagggtc
    50821 ttactgaatg aaccgcctaa aagaaaaata tcttaaagaa gtaactccat cattgatgga
    50881 aaaatttaac tatagctctg ttatgcaaac acctaaagtt gaaaaaatcg tcatcaacat
    50941 gggtgttggt gatgcggtat caaacgctaa aaacttagat aaagcagttg aagaattaac
    51001 tttgatcact ggtcaaaaac caatgattac aaaagctaaa aaatcaatcg ctggattccg
    51061 tttacgtgaa ggaatgccaa ttggtgcaaa agttacattg cgcggagaaa gaatgtacga
    51121 attcttagac aaattggttt ctgtttcact accacgtgta cgtgacttcc atggtgtaag
    51181 taaaaaagcc tttgacggtc gtggaaacta tactttaggt attaaagaac aattgatctt
    51241 cccagaagta gattatgatt tagtagataa agtacgtggt atggacatcg ttattgtaac
    51301 aacagcaaac tctgatgaag aatctcgtga gttgttgaca caattaggca tgccattcca
    51361 aaaataatta aaggaggcga actacgtggc taaaaaatca atgattgcta aaaacaaacg
    51421 tcctgcaaaa ttttcaacac aagcttatac tcgttgcgaa cgttgcggac gtccacattc
    51481 agtttatcgt aagttccatc tttgccgtat ttgcttccgc gaacttgcct ataaaggtca
    51541 aattcccggc gtgaagaaag ctagctggta aaaagtaaat tcgcataaga aggaggtaaa
    51601 agatcaatgg tcatgacaga tccaattgca gattttctaa ctcgtatccg taacgcaaac
    51661 atggttaaac atgagtcttt agaagtacct gcatcaaaaa ttaaacgtga catcgctgaa
    51721 atcttgaaac gtgaaggttt cgttcgtgat gttgaataca tcgaagatga caaacaaggc
    51781 gtgatccgtg ttttcctaaa atttggtaaa aacggcgaac gtgttatcac aaacttaaaa
    51841 cgtatctcta aaccaggttt gcgtgcttat gtcaaagctg acgaagtacc aaaagtattg
    51901 aacggtttag gtatcgcaat catttcgact tctgaaggtg ttgtcactga taaagaagct
    51961 cgtgaaaaaa atatcggcgg cgaagttatc gcttacgtat ggtaatcaag tagaatctac
    52021 aaggaggtgt ctttaagtga gccgtatcgg aaataaagtc gttgttatcc ctgaaggagt
    52081 aacagttact caagacggaa acaacgttac agttaaagga ccaaaaggtg aattgactcg
    52141 tactttttca gcagatatca aaatgaatat cgaaggaaac gaagtaactt tcactcgtcc
    52201 aaacgacagt aaagaaatga aaacaattca tggaacaact cgtgcgaact tcaacaacat
    52261 ggttgtaggt gtcagcgaag gtttccaaaa agcgttagaa ctaatcgggg ttgggtaccg
    52321 tgcacaatta caaggatcaa aacttgtatt gaacgttggt tactcacatc cagtagaaat
    52381 cacaccacca gctggagtaa ctgttgaagt accagctaac acacaagtaa ttgttaaagg
    52441 tgcgaacaaa gaagaagttg gcgaattagc tgcaaacatt cgtggaactc gtcctccaga
    52501 accttataaa ggtaaaggta ttcgttatgt tggcgaatat gtacgccgta aagaaggtaa
    52561 aactggtaaa taatcgttta gaaaaattgc atagaagcca gcagcaggaa aaaggcattt
    52621 ggctgaagtt taccttcaaa aaaatacatt tttacttgtg ccgcagcttc tatttttcga
    52681 aacgtattta ctgcttgaaa tagtagtaca ataaaaataa agaggtgaca attgtgatta
    52741 caaaaccaga taagaacaaa acacgtcaaa agagacatcg tcgtgtacgt aacaatatct
    52801 ctggtactgc tgagcgccca cgcttgaacg tttttcgttc taacaaaaac atctacgctc
    52861 aaattattga tgacgtagcg ggtgtaacgc tagcaagtgc ctctaccttg gataaagaaa
    52921 tttcaggtgg aacaaaaaca gaagcagcac aagctgtcgg taaactagtt gctgaacgtg
    52981 cagctgaaaa aggcattaaa gtagtagtct ttgaccgtgg tggatacctt taccatggcc
    53041 gtgtgcaagc tttagctgaa gctgctcgcg aaaatggact agaattttag aagaaggagg
    53101 aataccattc atggtttata tcgatccaaa acatttggaa ttagaagacc gcgttgttgc
    53161 aattaaccgt gtaacaaaag ttgttaaagg tggacgtcgt ctacgttttg ctgctttagt
    53221 tgttgtcggt gacaaaaacg gacacgtagg gtttggtaca ggtaaagctc aagaagttcc
    53281 tgaagcaatc cgtaaagcaa ttgaagatgc gaagaaaaac ttagttgaag tacctatggt
    53341 tggttcaaca atcccacacg aagtaatcgg tgcttttagt ggtggtagaa tcctaatgaa
    53401 acctgctgta gaaggttctg gggttgctgc tggtggacca gttcgtgccg tattagaatt
    53461 agctggggta gcagatatca cttctaaatc tttaggctca aatacaccaa tcaacgttgt
    53521 tcgcgcaaca gttgaaggtt tgaaacaatt gaaacgtgca gaagaagttg cagaacttcg
    53581 cggcaaatca gttgaagaat taatcggata aggaggacaa caataatggc tgaattaaaa
    53641 gttactttaa aacgcagtat tatcggacgt cctcaaaacc aacgcgatac agttaaagcg
    53701 ttaggtctta caaagattaa cagttcagtg gttaagcctt ctaatgaagc aattaaaggc
    53761 atgatcaata ctgtttctca cctagtggac gttgaagaaa tttaatttag aaaaatcata
    53821 actagaacat taaggaggtg ccaaacctat gaaacttcat gaattaaaac ctgctgaagg
    53881 ttcacgccaa gtacgtaacc gtgttggtcg tggtacttca tctggtaacg gaaaaactgc
    53941 cggacgcgga caaaaaggac aaaaagctcg ttcaggcggc ggtgtgcgtt taggatttga
    54001 agggggacaa acaccattgt tccgtcgttt accaaaacga ggattcacaa acgtgaaccg
    54061 taaagactat gcagtcatta atcttgatgt attgaaccgc tttgaagacg gagctgaagt
    54121 aactcctgtt gctttagttg aagctggaat cgtgaaaaac gaaaaagctg gaatcaaagt
    54181 attagctaat ggggaactaa acaagaaatt aactgtgaaa gcagcaaaat tctctaaagc
    54241 agctcaagaa gcaattgaag cggctggtgg atcaatcgag gtgatctaat gtttagacta
    54301 ttaaaagatg cttttaaagt aaaagacatt agatcgaaaa tcctatttac tgtatttgtg
    54361 ttgtttgtat ttcgcctagg tgcacatatt actgtaccag gcgtaaatgc tgcttcattg
    54421 caaaaccttt cttctttgcc atttttcaac atgttgaact tggtaagtgg tagtgcgatg
    54481 caaaactttt ccattttctc aatgggggtt tcaccataca ttactgcttc tatcgtcatt
    54541 cagcttcttc aaatggacat cgtgcctcga tttgttgaat ggtcgaaaca aggggaagtt
    54601 ggtcgtaaaa aactgaatca agcgactcga tatctgacat tagtattggc atttatccaa
    54661 tctgtcggta tcactgctgg attcaatcaa tacgctcaat taggtttcgt gaataatcct
    54721 aacgtagcaa cttacgtaac gatcggtttg attctaacag ccggtacgat gtttgttact
    54781 tggctaggag aacagatcac agaaaaaggt atcggaaatg gcgtatcaat gatcattttt
    54841 gcaggtatca tttctagatt gcctgaaagt atcagagaaa tttatgaaga ttactttata
    54901 aatattgatc cttcagacat atggaaatct gctatttttg tggccatttt actagtagcg
    54961 gtcttgttga tcgtgacatt cgtaacattt ttccaacaag ctgaacgcaa gatcccgatc
    55021 caatatacga aacgcgtagc tggcgcgcct acaagcagct atctgccgtt gaaagtaaat
    55081 gcagctggag ttattccagt tatctttgct agttcgttta ttgctacgcc aaatgctgtt
    55141 ttacaagcat tgagcggtag attcggttct gaaaactggt acaaagtgat gatggagatc
    55201 tttaactata atacagcacc tggtgctacg atttatacga ttctgatcgt tgccttcact
    55261 ttcttctacg cctttgttca agtaaaccct gagaaattag cggaaaactt gcaaaagcaa
    55321 ggaagttata taccaagcgt acgccctggt aaggggactg aagagtatgt ctcaagatta
    55381 ctgatgcgtt taagtacagt tggtgcagtc ttccttggtt tagtggcatt gcttccaatc
    55441 attgctcaaa tggtttggga tcttccacaa tcaatcggat taggcggtac aagcttactg
    55501 atcgttatcg gtgtagcttt agaaactgcg aaacagttag aaggcttaat gctgaaacgt
    55561 aaatatgttg gattcattga gtaagaaagc gtgttgaggt ttcccctcaa cacacgttct
    55621 cacacattta ttaggaggga aaacaatgaa cctcatttta atggggctgc caggcgcagg
    55681 taaaggaaca caagctgaaa aaatcattga tgcttatggt attccgcaca tctcaacagg
    55741 agatatgttc cgcgcagcga tgcaaaacga aacagctctt ggcctggaag caaagtctta
    55801 tatggataaa ggtgcattag ttcctgatga agtaacaaat ggaatcgtga aagagcgact
    55861 agctgaacca gatacagaga aaggcttctt attagatggc tttccacgta cgctagatca
    55921 agcaaaagct ctggacgcaa tgctaaaaga tttgaataaa aaaattgatg ctgtcatcga
    55981 tatccatgtt ggtgaagaaa tcttggtcga acgtctagcc ggccgattta tctgcagcaa
    56041 ttgtggagca acttaccata aaattttcaa ccctacaaaa gttgaagaca catgtgatcg
    56101 ttgcggtggg catgaattct atcaaagaga agatgataaa cctgagacgg ttaaaaatcg
    56161 tctggctatc aacatcaaaa atagtgaacc aatcttggct tattataaag aacaaggttt
    56221 gctaaacact attgatggtg ctcgtgaaat cgatgctgta tttgcagatg tacaaaaaat
    56281 cattgaaaaa tagcacgatt gcccgtagcc gacttgcatt atgcagttac tcttgtcaag
    56341 ttcaataaat tatgatagaa tatgtcagtc cgacttctag agaatcctct agatgatcca
    56401 ttttgagaat tttgaggtgg gaactgcagt ttccgccatt ttatcgtgtg aaaatgcgaa
    56461 acaagtacaa ggaggtactg tgcgtggcaa aagaagatat gattgaagtc gaaggtacag
    56521 tcgtcgaaac tttgccgaat gcaatgttta aagttgaact agaaaacgga caccaagttc
    56581 ttgctactgt ttcaggtaaa attcgtatgc attacatccg tatcttacct ggtgacaaag
    56641 taacggttga attgtctcca tacgatctta accgtggccg tattacttat cgctttaaat
    56701 aattgtactc cgtaaaacta caggaggtat tatcatgaaa gtaagaccat cagtaaaacc
    56761 aatgtgcgaa cattgtaaag taattcgtcg taaaggacgc gttatggtga tttgcccagc
    56821 aaatccaaaa cataaacaac gtcaaggata attggaggtg ctataaatat ggctcgtatt
    56881 gcaggagtag atattcctcg tgataaacgt gtagtagttt cacttactta tatctatggt
    56941 attggtaaca ctactgctaa aaagatctta gctgatgctg gtgtatctga agatgttcgc
    57001 gttcgtgaat taacgaatga acaaacagat gctatccgtg cagaagtaga taaattaaaa
    57061 gttgaagggg atcttcgtcg tgaagtgaac ttgaacatca aacgtttgat ggaaatcggt
    57121 tcttaccgtg gaatccgtca tcgccgtgga ttgcctgttc gtggacaaaa cacgaaaaac
    57181 aatgcacgta ctcgtaaagg cccagctcgc gctatcgctg gcaagaaaaa ataattctta
    57241 agtgaaggag gttaaaactt catggcagca aaaaaagtga atcgtaaacg ccgtgtgaag
    57301 aagaatatag aagcaggtat tgcacatatc cattctacat tcaataacac tatcatcatg
    57361 atcactgata ctcacggaaa tgcattagcg tggtcatcag ctggttcatt aggtttcaaa
    57421 ggaagcaaaa aatcaactcc ttttgccgct caaatggcag cagaaactgc tacaaaagca
    57481 gcaatggaac acggattaaa gactgttgaa gtaacagtta aaggacctgg ttctggacgt
    57541 gaagcagcaa ttcgttcatt acaagctaca ggtttagaag tgactgcaat tcgtgacgtg
    57601 actccagttc ctcataatgg tgcccgccct ccaaaacgcc gtcgtgttta atgagtgccg
    57661 ctcattttga gttttatcag taacgtcatt gaacaagaca cttttcgttt tgaaaggggt
    57721 aaagataaga atgattgagt tcgaaaaacc aagaatcgca aaaattgatg aagaaaaaga
    57781 ttatggcaag ttcatcgttg aacctcttga aagagggtat gggactactt tagggaattc
    57841 cctacgtcgt attttattat cttctttgcc aggtgctgcc atcactaata ttcaaatcga
    57901 tggtgtactg catgaattct ctaccatcaa aggtgttaga gaagacgtca ctcaaatcat
    57961 cttgaacatt aaaggcttag cgctgaaaat gtatggccaa gaagaaaaaa cccttgaaat
    58021 cgatattacc ggacctgcta cagtaactgc tggcgatatt atcgttgata gtgatgtaga
    58081 aattcttaac aaagatatgt acatctgtag tgtctctgaa ggagctacgt tccatgctcg
    58141 cttaacagtg aaacctggac gtggttatgt tcaagcagat gaaaataaaa aagaagatat
    58201 gccaattggc gttcttccag tcgattcaat ctacacacct gttcgtcgtg tgaactatca
    58261 agttgagaac acacgtgttg gacaccgtga agattttgat aaattgacga tggagatttg
    58321 gacagatggt tcaattgaac cgttggaagc aatgagtttg tctgcgaaaa tcatgactga
    58381 acatttggat atttttgtga acttaactga tgaagcaaaa aatgctgaaa tcatggtcga
    58441 aaaagaagaa acacaaaaag aaaaaatgtt ggaaatgacg atcgaagagt tagacttgtc
    58501 tgttcgctct tacaattgtt tgaaacgtgc aggaatcaat actgtacaag aacttacaaa
    58561 taaatctgag cctgaaatga tcaaagtccg taacttagga cgtaaatcat tagaagaagt
    58621 taaagcaaaa ttgcacgact taggtttagg tttacgtaaa gaagattaaa accttttacg
    58681 aaggagggaa accaacgtga gttatcgtaa actaggacgc acatctagcc aacgtaaagc
    58741 gatgttgcgt gatttaacaa ctgatttatt aatcaacgaa cgtattgtga ctactgaagc
    58801 tcgtgcgaaa gaagttcgct caactgcaga aaaaatgatc actttaggta aacgcggaga
    58861 tttgcatgca cgtcgtcaag ctgcggcttt cgtacgtaat gaagttgcca gcgtgcgtga
    58921 agaaaatgag gacatcgtca ttgaatcagc tttacaaaaa ctgttcaacg atattgcacc
    58981 tcgttacgca gaacgtcaag gcggatacac acgcattttg aagacagaac caagacgcgg
    59041 tgatggtgca ccaatggttg tcttagaact tgtctaaaat cacactaata acatcacttt
    59101 atagatgatt cttttagagt gttatgatgt tggaagatat ttttccgagt ctagctcagc
    59161 gctgctcctc aagcgaatat cgcttgggga gtaagcactc atcataaagt gtttttttat
    59221 accttcaatt acctgtcatg acagatatgt ttgaaggcat aaaaaaacat tttaagcgag
    59281 aaataattga aaattttgtc tttttttgat agtgttagta ggaactttag gatgaagaag
    59341 gagtaatcat ggagccaatt attgaattag aaaagataaa ttataaatac cagccagatg
    59401 atcttcgccc cgcattgaaa gatgtctcct ttacaattga taaaggtgag tggatcgcta
    59461 ttattggaca caatggttca ggaaaatcga cacttgccaa aacgatcaat ggattgcttc
    59521 tgccagaatc agggatcgtg aaagtgggaa atcaaatatt ggatgaagaa aatatttgga
    59581 cgatccgaca gatggttgga atggtttttc aaaatccaga caatcagttt gttggttcga
    59641 cagtagaaga tgacgttgct tttggtcttg aaaatcaagg gattcccaga gaagaaatgc
    59701 tagtgcgtgt gaaagatgca cttgagaaag ttagaatggc tgagtttgct tcacgcgagc
    59761 ctgctcgttt atcaggaggg caaaaacaac gtgttgccat tgccggcgtg gttgccttac
    59821 gacctgatat cattatttta gatgaagcaa ccagtatgct agatccagaa ggtcgtgaag
    59881 aagtgatctc tacgatcaag aagatcaaag aagaaagtca attgaccgtt atatctatca
    59941 ctcatgatat tgatgaagca gctaatgcca atcggatact agtgatgaga caaggcgaac
    60001 ttgtccgtga aggtacacca aaagaaattt tttctgctgg tcctgaactg atcgacttag
    60061 gtctagatct accatttcct gaaaaactga agagcgcact gaaagaacgt ggggttgatg
    60121 tgcccagtga atatatgaca gaagaaagga tggtggattg gttatggaca tccgttttga
    60181 acaagtagac ttcacttatc agccgaatac accatttgaa caaagagcct tatttgacat
    60241 caatatgacg atcaaagaaa acagttatac tgcattagta gggcataccg gaagcgggaa
    60301 atcaacctta cttcagcatt tgaatgcgct tgttaagcca acaagcggta cagtccatat
    60361 tggagaacga gatattcagc cggatacgga taataagaat ttaaagccca tccgaaaaaa
    60421 agttggcatc gtctttcagt ttccagaagc acagctattc gaagaaacgg tagcaaaaga
    60481 cattgctttc ggtcctaaaa actttggtgt cagcgaagaa gaagcactag tcctagcaaa
    60541 agaaacatta gaacaagttg ggctggatga aagctatttg gaacgttcgc catttgaact
    60601 ttcaggaggg caaatgcgta gagtagcaat cgctggtgtg cttgccatga ggccggaagt
    60661 acttgtattg gatgaaccaa cggcaggact tgatccccag ggtagaaaag aaatgatgga
    60721 gatgttttgg cgtcttcata aggaacagca gatcactatt gtattagtta cgcatttaat
    60781 ggatgatgta gccaattttg cagattatgt ctatgtgttg gaaaagggac gaatcgttaa
    60841 tagcggggag ccgcaagagg tctttcaaaa cattgaatgg ctaaaagaaa aacaactagg
    60901 cgtacctact gccaccgagt ttgcagaaga attaatggct aaagggatga actttgctac
    60961 cttgcctttg acagctgaag aattagcaga cgctatcgtc cattatgctg gaggaaatgc
    61021 ccatgatgaa taaattgata tttggtcgtt atatgcctgg agattccttg atccatcgat
    61081 tggatccccg agctaaatta ttagccagtt tttattttat cggaatcatt tttttagcaa
    61141 ataattggga aacgtacctt ttgttggcat ttttcacatt actttctgtc ttcttgtcaa
    61201 aagtagattt gaaatttttt atccgaggca ttcgcccatt gatctggcta atcctcttca
    61261 ctgtagcttt gcaggtcttg tttacaagtg gcggagaaac ttattggagt tggggtgttt
    61321 tccatatcac tgaatttggt gtgatgaacg gcctctttat tttctgtcga ttcgtgttga
    61381 tcatttttat gtcgactcta ctcacgctta ctacaccgcc tttggaatta tcggatgcga
    61441 ttgagtactt gcttcgtcca ttgaaagccg tacggttccc agtccacgaa atttcattga
    61501 tgctgtcgat tgctcttcgt tttgtgccta cattgatgga cgaaacagaa aagatcatga
    61561 acgctcagcg cgctcgcggt gttgattttg gtgaaggaaa cctagttcag aaaatgaaag
    61621 cagtcattcc tttgctgatt cctttatttg tcagcagctt caaccgtgcg gaagatcttg
    61681 cgactgctat ggaagcaaga ggctacaaag gtggggaagg aagaacgaaa tatcgtgtat
    61741 tgcattggca taatagagac acgatggtta tcattgcttt tgtattatta actgtgctac
    61801 tgatcttttt gagaggataa acgttcagtg ggccgctatc tattcttttc ttgctgatct
    61861 gtttgcaaga aaggatgcga gcagtgtatg acaagaaata ttagggtctg tggcagacta
    61921 aggtcacagg cctctttctt ttatctgaaa agaaagaacg aaaaaatttt ataaaaaaat
    61981 cattattcca gataaccttt taggaacaaa ggagagaaaa acatggtacg ttacaaagca
    62041 atcattgcat acgacggaac aaattttaat ggattccaaa aacagccaaa tgggcgtact
    62101 gttcaagaag aagtagaaaa aacattacaa aaaatggcaa atggaaaaga aatcacggtc
    62161 tttggttcgg gaaggacaga tgccggagta catgcgattg ggcaagtaat ccattttgat
    62221 tatccagagg agcgtccgtt agaacgaatg cgtttcgcgc tagataccca gtcaccagag
    62281 gatattgctg taagacaagt agaaattgtt tcagaagact tccacgcaag atatttggtc
    62341 aaagaaaaga cgtatcaatt tcgagtggat atagggaaac cacgcagtcc ttttcgacgc
    62401 cattatgcaa gttattttcc ttaccctctt gatttggaaa aaattcagcg ggcgcttcct
    62461 gatttattag ggactcacga tttcacctct ttttgtgcat caggaagctc gatagaggat
    62521 aaagtacgta cgatctacga ggctaagatg gaggtaaatg aaacaaaaga cgaattgttg
    62581 tttacattta ggggaaatgg cttcttgtat aagatgatac ggatcttagt aggaacgctt
    62641 ttgaaaattg gcaatggccg attgcctgaa gatagtatcc cagatattat tgcgaaaaaa
    62701 gatcgtaatg cagcaggacc tacagcacat cctgaaggac tttatttgta tgaagtgaaa
    62761 tatgaataag aggttgtgac agaagtggtc agcttcaaga aataagaagg aatttacgaa
    62821 aattacttct caaaattttg caaaatttcg gcttattttc gaaggagcta cttctggaac
    62881 accgtgaatc agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa caaccaaaca
    62941 aaaatagctc gtcatatttt tcgtttggtt gggcttatta ccgcagatgc aagcttttga
    63001 acaccgttta aggaagaggt tgtgaaatca gcgttttgac ctgagtatta gagaaacaaa
    63061 cggaaaaata gttcctcata ttttgccgtt tgttgagcta ataccgaagg tcagctgatt
    63121 gaacaccgtt taagaaagag gtcgtgagcc tgtcatttaa ctctgagtca caagtaacaa
    63181 tttcaaaaaa cagcttctca tctttgatga atatcgtgac ttgtggacga ggcgttgata
    63241 agtgaatcat ctttttgtta cctatttttt ctgtaaccaa aaaacgatgg aacgttgttt
    63301 tgattgccct taatgaggac agtcggaaca ggtttgtcat ttttatattt aaatggcaca
    63361 aatttttcta attatttgtc atttagcgct gaaaattttt gctatttatc taaaaaagtg
    63421 ataactactt aagatgaagc agaatattta cgccatacgg catacaaccg cgaaaaatat
    63481 aaaaaaaaga aaacgattga acgcgttttt gcagtcgcaa aggaaaagca tggaatgcgc
    63541 tacatcaagt atcgagactt ggaaaacaat caggtgtata cgctgattgt ttttgctgca
    63601 atgaatctga aaaagttgtc cacttggcag ttggaacata tgtcttcata tcttttatta
    63661 tacaaaaata gcaaaagcac cagtctacac tcttagtaaa gaggaaactg atccttttgt
    63721 ctacattctt aaagtactta aactaagtac tttattttac tctttaggat tgatacagta
    63781 gcatctatcc ctttattaat aatcttttat ttttttaaat aaagatgttg tctccatctt
    63841 caggcactaa aactttttcg gaaattcctt tttctttatt gaaagacttt aattcttctc
    63901 ttgacagtcc ccaatggttt acagcttcca tatgaacggc aataattgtg gaatctggta
    63961 ttgctttatg caattcatat aaatcgtctt tccccataat aagagattct ccaactaaaa
    64021 aatgattatc tccagcattt gctactatga tttctggatt atactgatca atagtttgtt
    64081 taacagcttc ataccaaact gtatctcctg taaagtatag tgtcttctca gtcgaatgtt
    64141 tgaaaacaat accgcaaaca ttacctacat aattcaagat ttctcctctg ccatgtttgc
    64201 cttttgtttt aaccaattgt atagattcaa aaactgtgtc ttctcgtagt acctccacat
    64261 ttttaaaacc atatagtcga atttcattcg catcattttc atcttgcaca aataatttta
    64321 tttctttagg taggacctct ttcgctatat cgtcccaatg atctagatgt aaatgtgtta
    64381 caataacagc atcaataccg ttgataatat cttcgactgg cattggcaaa tcaactagag
    64441 gattcatttg atcttttctt ggtgatggaa aaggaccttt cgaaataaat ggtggaagtg
    64501 ttcctttttc cgctaacatt ggatcaatta aaaatttttt acctccatag tctaagatag
    64561 ctgttgcatt acgaatgtga tgtatattca taaacgttgt ctcctttttg ttgatatgaa
    64621 atatttttag tataattcaa ttccatacaa taaataaacc gaacaaaaaa agtcttttac
    64681 tatttttact taatttatga aaggttgttt accatgttag accaaacaga tataaatatc
    64741 attgaggaac tatcaaaaaa tagtcgaatc acaatgaaag aacttggaga aaaagtacat
    64801 ttgactggac ccgctgtctc ggcgagagtg acaaaactag aggaaagtgg agttattgaa
    64861 aattatacag taaaattaaa tatggaaaag ctagggtttt cgattcacgc ttttttaatt
    64921 ataattacgc aaaatttaaa tcataaaccc tatttatcat ttattaaaaa tcatgaaaaa
    64981 ttcttgatta gaaattataa gattagtgga gggggctgtt atcttttgga atgtagattt
    65041 acttcaaaaa aatcaatgaa cagctttttg gaacagctta atgaatatgc gaattataaa
    65101 ttatctattg ttatagatta ataataaaac tagcagatgg taaaaatact aatatgcgag
    65161 acacacattc aaccataact atataactta tcaatttaaa actaaactga tggaaacaag
    65221 taaggcaaaa acatttatat tttgccctac ttattttttt aattaaattc attgatgatt
    65281 catatttaga aaattctatg aaggccaaat gagtatcctg tcactttttt agataaatag
    65341 caaaaatttt cagcgttaaa tgacaaataa ttagaaatat ttgtgccatt taaatataaa
    65401 aatgacacca agtatatcat gaacgcacaa aaagaccaac agggtatacc ctgttggtct
    65461 aaataa
//
LOCUS       DBBGRF010000009        65291 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000009 DBBGRF010000000
VERSION     DBBGRF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 65291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.009"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..211
                     /locus_tag="ACIZD4_000661"
     CDS             <1..211
                     /locus_tag="ACIZD4_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989617.1"
                     /translation="NRSDTRCGSFLYILYEVFFIPYEKISLKIKKDENKRFSIKRRPF
                     IFCLYLCEKRKRAQHIKLLLIVCLL"
     gene            297..1511
                     /locus_tag="ACIZD4_000662"
     CDS             297..1511
                     /locus_tag="ACIZD4_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HGC5989618.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1542..2969
                     /locus_tag="ACIZD4_000663"
     CDS             1542..2969
                     /locus_tag="ACIZD4_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC5989619.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            2992..3918
                     /gene="glsA"
                     /locus_tag="ACIZD4_000664"
     CDS             2992..3918
                     /gene="glsA"
                     /locus_tag="ACIZD4_000664"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HGC5989620.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            4126..5586
                     /locus_tag="ACIZD4_000665"
     CDS             4126..5586
                     /locus_tag="ACIZD4_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989621.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETQFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            5807..7570
                     /locus_tag="ACIZD4_000666"
     CDS             5807..7570
                     /locus_tag="ACIZD4_000666"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HGC5989622.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            7654..8112
                     /locus_tag="ACIZD4_000667"
     CDS             7654..8112
                     /locus_tag="ACIZD4_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGC5989623.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            8221..8904
                     /locus_tag="ACIZD4_000668"
     CDS             8221..8904
                     /locus_tag="ACIZD4_000668"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGC5989624.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            9051..9665
                     /locus_tag="ACIZD4_000669"
     CDS             9051..9665
                     /locus_tag="ACIZD4_000669"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HGC5989625.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            9681..9887
                     /locus_tag="ACIZD4_000670"
     CDS             9681..9887
                     /locus_tag="ACIZD4_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989626.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     regulatory      10112..10278
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            10452..11558
                     /locus_tag="ACIZD4_000671"
     CDS             10452..11558
                     /locus_tag="ACIZD4_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGC5989627.1"
                     /translation="MIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLSWSVIFLAR
                     SVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQFQPSELANL
                     FLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIAWVIFWAAA
                     VPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDSFIDSHGAG
                     YQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIGALCVLFLL
                     FSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGVPLPFVSYG
                     GTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            11650..12405
                     /locus_tag="ACIZD4_000672"
     CDS             11650..12405
                     /locus_tag="ACIZD4_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC5989628.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            12463..14502
                     /locus_tag="ACIZD4_000673"
     CDS             12463..14502
                     /locus_tag="ACIZD4_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HGC5989629.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(14611..15762)
                     /locus_tag="ACIZD4_000674"
     CDS             complement(14611..15762)
                     /locus_tag="ACIZD4_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGC5989630.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(15916..16446)
                     /locus_tag="ACIZD4_000675"
     CDS             complement(15916..16446)
                     /locus_tag="ACIZD4_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HGC5989631.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(16545..16895)
                     /locus_tag="ACIZD4_000676"
     CDS             complement(16545..16895)
                     /locus_tag="ACIZD4_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGC5989632.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(17052..18575)
                     /gene="ahpF"
                     /locus_tag="ACIZD4_000677"
     CDS             complement(17052..18575)
                     /gene="ahpF"
                     /locus_tag="ACIZD4_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HGC5989633.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGARSINVPGEKEFKNKGIAY
                     CPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKLVS
                     LANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLDGT
                     IEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMRT"
     gene            complement(18585..19148)
                     /gene="ahpC"
                     /locus_tag="ACIZD4_000678"
     CDS             complement(18585..19148)
                     /gene="ahpC"
                     /locus_tag="ACIZD4_000678"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HGC5989634.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(19292..19954)
                     /locus_tag="ACIZD4_000679"
     CDS             complement(19292..19954)
                     /locus_tag="ACIZD4_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5989635.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            20138..21784
                     /locus_tag="ACIZD4_000680"
     CDS             20138..21784
                     /locus_tag="ACIZD4_000680"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HGC5989636.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            21775..22857
                     /gene="uxuA"
                     /locus_tag="ACIZD4_000681"
     CDS             21775..22857
                     /gene="uxuA"
                     /locus_tag="ACIZD4_000681"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HGC5989637.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(22965..24518)
                     /locus_tag="ACIZD4_000682"
                     /pseudo
     CDS             complement(22965..24518)
                     /locus_tag="ACIZD4_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            24666..25807
                     /locus_tag="ACIZD4_000683"
                     /pseudo
     CDS             24666..25807
                     /locus_tag="ACIZD4_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(25933..27012)
                     /locus_tag="ACIZD4_000684"
     CDS             complement(25933..27012)
                     /locus_tag="ACIZD4_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC5989638.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(27115..27555)
                     /locus_tag="ACIZD4_000685"
     CDS             complement(27115..27555)
                     /locus_tag="ACIZD4_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC5989639.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(27612..28022)
                     /locus_tag="ACIZD4_000686"
     CDS             complement(27612..28022)
                     /locus_tag="ACIZD4_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HGC5989640.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(28202..28636)
                     /locus_tag="ACIZD4_000687"
     CDS             complement(28202..28636)
                     /locus_tag="ACIZD4_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC5989641.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(28736..29584)
                     /locus_tag="ACIZD4_000688"
     CDS             complement(28736..29584)
                     /locus_tag="ACIZD4_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC5989642.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            29973..31739
                     /locus_tag="ACIZD4_000689"
     CDS             29973..31739
                     /locus_tag="ACIZD4_000689"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HGC5989643.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            31841..33100
                     /locus_tag="ACIZD4_000690"
     CDS             31841..33100
                     /locus_tag="ACIZD4_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC5989644.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            33247..34548
                     /locus_tag="ACIZD4_000691"
     CDS             33247..34548
                     /locus_tag="ACIZD4_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5989645.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            34551..35402
                     /locus_tag="ACIZD4_000692"
     CDS             34551..35402
                     /locus_tag="ACIZD4_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGC5989646.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            35415..36230
                     /locus_tag="ACIZD4_000693"
     CDS             35415..36230
                     /locus_tag="ACIZD4_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HGC5989647.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            36381..37547
                     /locus_tag="ACIZD4_000694"
     CDS             36381..37547
                     /locus_tag="ACIZD4_000694"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC5989648.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            37777..38424
                     /locus_tag="ACIZD4_000695"
     CDS             37777..38424
                     /locus_tag="ACIZD4_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HGC5989649.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            38508..39452
                     /locus_tag="ACIZD4_000696"
     CDS             38508..39452
                     /locus_tag="ACIZD4_000696"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGC5989650.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            39587..41038
                     /locus_tag="ACIZD4_000697"
     CDS             39587..41038
                     /locus_tag="ACIZD4_000697"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HGC5989651.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            41059..41895
                     /locus_tag="ACIZD4_000698"
     CDS             41059..41895
                     /locus_tag="ACIZD4_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGC5989652.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            41895..42554
                     /locus_tag="ACIZD4_000699"
     CDS             41895..42554
                     /locus_tag="ACIZD4_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC5989653.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            42680..43369
                     /locus_tag="ACIZD4_000700"
     CDS             42680..43369
                     /locus_tag="ACIZD4_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989654.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            43375..44331
                     /locus_tag="ACIZD4_000701"
     CDS             43375..44331
                     /locus_tag="ACIZD4_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HGC5989655.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            44375..44887
                     /locus_tag="ACIZD4_000702"
     CDS             44375..44887
                     /locus_tag="ACIZD4_000702"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5989656.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(45143..45691)
                     /locus_tag="ACIZD4_000703"
     CDS             complement(45143..45691)
                     /locus_tag="ACIZD4_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGC5989657.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(45780..46961)
                     /locus_tag="ACIZD4_000704"
     CDS             complement(45780..46961)
                     /locus_tag="ACIZD4_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HGC5989658.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(47197..48705)
                     /locus_tag="ACIZD4_000705"
     CDS             complement(47197..48705)
                     /locus_tag="ACIZD4_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGC5989659.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            48864..49055
                     /locus_tag="ACIZD4_000706"
     CDS             48864..49055
                     /locus_tag="ACIZD4_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989660.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            49258..50175
                     /locus_tag="ACIZD4_000707"
     CDS             49258..50175
                     /locus_tag="ACIZD4_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HGC5989661.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            50168..51241
                     /locus_tag="ACIZD4_000708"
     CDS             50168..51241
                     /locus_tag="ACIZD4_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989662.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            51389..51907
                     /locus_tag="ACIZD4_000709"
     CDS             51389..51907
                     /locus_tag="ACIZD4_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989663.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            51888..52280
                     /locus_tag="ACIZD4_000710"
     CDS             51888..52280
                     /locus_tag="ACIZD4_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HGC5989664.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            52356..53291
                     /locus_tag="ACIZD4_000711"
     CDS             52356..53291
                     /locus_tag="ACIZD4_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC5989665.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            53424..54203
                     /locus_tag="ACIZD4_000712"
     CDS             53424..54203
                     /locus_tag="ACIZD4_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGC5989666.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            54196..54513
                     /locus_tag="ACIZD4_000713"
     CDS             54196..54513
                     /locus_tag="ACIZD4_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGC5989667.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            54757..56367
                     /locus_tag="ACIZD4_000714"
     CDS             54757..56367
                     /locus_tag="ACIZD4_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC5989668.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            56524..57372
                     /locus_tag="ACIZD4_000715"
     CDS             56524..57372
                     /locus_tag="ACIZD4_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC5989669.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            57603..58082
                     /locus_tag="ACIZD4_000716"
     CDS             57603..58082
                     /locus_tag="ACIZD4_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HGC5989670.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            58115..60343
                     /locus_tag="ACIZD4_000717"
     CDS             58115..60343
                     /locus_tag="ACIZD4_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5989671.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            60472..62115
                     /locus_tag="ACIZD4_000718"
     CDS             60472..62115
                     /locus_tag="ACIZD4_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGC5989672.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(62188..62733)
                     /locus_tag="ACIZD4_000719"
     CDS             complement(62188..62733)
                     /locus_tag="ACIZD4_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGC5989673.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QDHVTALRSRPKYIGGPRANY"
     gene            complement(62756..63241)
                     /locus_tag="ACIZD4_000720"
     CDS             complement(62756..63241)
                     /locus_tag="ACIZD4_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC5989674.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(63231..64043)
                     /locus_tag="ACIZD4_000721"
     CDS             complement(63231..64043)
                     /locus_tag="ACIZD4_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HGC5989675.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(64182..>65291)
                     /locus_tag="ACIZD4_000722"
     CDS             complement(64182..>65291)
                     /locus_tag="ACIZD4_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HGC5989676.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        21630 a        11672 c        12765 g        19224 t
ORIGIN      
        1 gaaccgtagc gacactcgct gcggttcttt tttatatatt ttatatgaag tattctttat
       61 tccttatgaa aaaatatctt taaaaataaa aaaagacgaa aataaacggt tttctataaa
      121 aagaagaccg tttatttttt gtctttattt gtgtgaaaaa cgaaaaagag cacaacacat
      181 caagctttta ttaattgtct gtcttttata aatgcaagta ttaattcaaa aaaacagaag
      241 aaaaaaacaa ctacaccttc ttttatactc gtaatcgtag aaaggaggcg aaaaaaatga
      301 atacattacc tatcaataca ggagatacag cattcatgat tttatgtaca gcaatggttt
      361 gcctgatgac tcctggtcta gctttttttt acggcggatt agcacggaag aataatatac
      421 taacgatcat gtctcaatct tttctctccg ttgggataac aacgattatg tgggtatttg
      481 gtggattcgg attggccttt ggacgggata tcggcggtgt tattggaaac ccggcagatt
      541 tctttttgat gagacatgtt acaagcttcc ccaacatgtt tcatggtgca acgattccat
      601 ttttaatgtt ctttctttac caactgatgt ttatcgtgat taccgttcct ttgatgacag
      661 gagcttttgc agggagattg aatttaaaag gctatattat acttgttatt ttttggaatc
      721 tgctgattta tttccctgtt tgccactgga tatggggtgg cggatttttg gatcagatgg
      781 gatttagaga tttcgctggt ggagcagtca tccacacgac agctggattc ggctctttag
      841 catgtatcct cacacttggt caaagaaaga ttcctttagg agaaagaagt cagcatagca
      901 gtcttatggc agctgctatc ggtacaggac tgctttggtt tggctggttc ggttttaatt
      961 ccggtggtgc acttcgagca gatgaacaag cagtcaatgc atttggttca acattcatcg
     1021 ctcttgcatt tgcgatgatt acttggctga tcattgcaaa agtaaaagga aatggctttg
     1081 attttgtcga cgtactaaca ggatccgttg ctggattggc agccattacg ccttgtgccg
     1141 gttatgtaga agcaaaaagt gccatgctga ttgggatcat tgcgggtatc gtctgtcatg
     1201 ctgctgttga ttttcgtaaa aagaaacaat gggatgatgc acttgatgtg tggggtgttc
     1261 atggcatggg cggattcaca ggtacgattc tgatagggat ctttgcatct aacagccatt
     1321 tactaacgaa tccaagcagc tggtacttct tagggattca agtgattggt gtcatcatta
     1381 ctgccgtgta tgcctatgtg ctgacaacag tgattttaaa atcggcgatg cactttacaa
     1441 cgatcactac tacaaaagaa gaacaagaag aaggattgga ctttttcttc tttggcaaca
     1501 aactcaattg aaacaaattc aaatagaaaa gaggaagatt catgcaacaa agcaaaacga
     1561 aaattcctgc aaaaaaatta acgttctttg gctttttggc tatgaccatc tcaatggtcg
     1621 tttcattata tgaatatccc acattcgcga cctcaggctt cagcttagta tttttcttgt
     1681 tattaggcgg tttgctatgg tttatccctg tggcattgtg cgcagcagag atggcaacgg
     1741 tgaaaggatg ggaaaaaggc ggtgtctata cttgggtcag tcgcacattg ggaaaacgat
     1801 tcggttttgc cgcaatcttt ttccaatggt ttgagataac agttggctac ttgaccatgc
     1861 tgtatttctt aactggtgca ttatcctatg caacgggtat tggtgctata caaaacaata
     1921 aatatctgaa attggcaatc ctattgatta ttttctgggc tattttactc tcacagttaa
     1981 aaggaaccaa atacacttca ttgattgctc ggatcggttt tgtagctggt atcttgttgc
     2041 cagcattagt cttgtttggc ttagggatcc attatgtcgc ttcaggcgct ccactacaaa
     2101 cgatactgtc tatgaaaaca ttgattcctg atttttcgaa attgcctacg ctggttgttt
     2161 ttgtttcctt tattttagca tatatgggcg tagaaacatc tgccagtcat gcaaatgaaa
     2221 tggaaaaccc taaaaaggat tatccattag caatgtttgt attggttatt ctggcaatca
     2281 ttttagatac ttttggcgga ttgaccgtcg ctactacagt acctcaacat ggtttgtctc
     2341 ttaatacagg ggtgattcaa tcgttagaat tcctattaag acacattgat ccaaatcttg
     2401 catggattgc gaaaattctt gcgattcttg tttgtttagg tgtcatcgga gaaattgctt
     2461 cttgggtaac ctctccttca aaagcacttc acgtagcagc agaagaagga ttacttcctg
     2521 aatattttgc aaaagaaaac acacacggtg ttcctgctca tttgatgatc gcaaatggga
     2581 tcgttgcaac aatctgggca gccgtcttta cattaagcgg cggggggaat aatctttcat
     2641 ttcttgcagc gatgtcattg actgttgtaa tctacctgat gttgtacttt atgtttttcg
     2701 cgggctattt gaagctggtt tttaaagatg acagtcttga aagagcctat caggttccag
     2761 gcggaaaagt tgtaaaagta atcgttgctt gtttaggtct tttgacttca ctttttgctt
     2821 tttgtatctc atttgttcca cctgctagta tcgcagctgg acagcatggg atttatgaaa
     2881 cgattctgat tgtttcttat cttatcgtct tagttattcc atttacgatc tacgcatgcc
     2941 gtcataaatt ccagcatgca gaaaaataaa aaatgaaagc tggttattca aatggaagta
     3001 aaagaattag aacaattgat tggaaaaaat ttccactatt atcaaacagg acaagtggcg
     3061 gattacattc cagcattagc tgaagtggat cccaaacaat taggtatggc gatttatgat
     3121 ttggatacaa aacaactgat tgagggagga gacgccgatg tgcgctttgc catcgaaagc
     3181 atgtcaaaag ttcccgtatt gttattagca atcaaagaca acggaataga aaaagtcttt
     3241 caaacaatca acacggaacc aaccggtttt gccttcaatt ctatcatgaa tatggaaatc
     3301 aatcatcgca aacatccaat gaatcctttt gttaatgcag gagcgattgc aacaacctcg
     3361 ttgattgccg gtaaagatgc agatgaaaaa tttgagcgaa tcttgtcatt tatgaaagag
     3421 atctgtgatg atcctaatat cacattgaat gaagaaatct atcattctga atcaagaaca
     3481 ggtgatatca atcgctctct tgcttactat atgaaaggta atcaaatgat cgaaggagac
     3541 gtaccggaga tactcgatgc ttatttcaga caatgctccc tcaatgtcac cgctacaggc
     3601 atagcaaaat tagctgctgt gctggcaaat aaaggaattg ctccttggaa tggcaaacaa
     3661 atcattactg aagaaagtgc tacaatcgtc aaatcaatta tgacaactgc tggtttgtat
     3721 gatgaatcag gagagttttc cgtccatgtt ggtgtacctg caaaaagcgg tgtaggcggc
     3781 gggttgatgg cagctgtgcc aaatcgttac ggcataggtg tcttcagccc ggcactagat
     3841 ccatttggta acagcgcagc tggtatccaa ttgttgaaag atgtagtcaa agaactagac
     3901 gctgacatct ttgaataacc attcttgaaa gaggctgggg taaaagtcca aacggctcaa
     3961 agctacctac aatgaggctg aaattgtgag cttgtttgac ttttgtccca gtttcttttt
     4021 ttattggttt ttgaaagggc ttttctaaat aaaaaggaaa caaaaatacg atttacagat
     4081 atgattaaat aaaatcataa gaaaaactgg aggcgtgtat caggaatgct ggaaaattac
     4141 atcgagcgaa atatatttag aaaagtgtat ctgtgtgaac aattatttga attccaagaa
     4201 atagacatcg aacaaacagc tatttctcta agggtgacta caccaacgat ccttcacgat
     4261 ctagaaagtc tagccgagtg tctagaatat tgtataaaag aacaagtaag agagaagcat
     4321 aagtataaac tcgtattcaa acatggtatt gctctttctg agctcacaca gtttctgtac
     4381 ggtcaatctt attttttaaa gtttttaagt tattatttta atggtatatt cacgagtaca
     4441 gaactggctg atcttgaatt tatttctttg agtaaagtat atacaatcaa aaaaatcgta
     4501 ttggattttt ttaaagaaaa tgattatttg aaaaataaag aaatcattat cccagaattt
     4561 gactcgcgga acatcttgct agctttagta cgttatgtca attgggaagg ctatgaaaat
     4621 aaaaatccgt atgtagaaga agcttgtaac gagttgattg attatgtaga gactcaattt
     4681 tttaaaagaa gatattcgga agatgaaaag tcctttatca tacgagaaat agagatcgca
     4741 atcggaagaa aggcatttcc ccttggactg aaagaagaag ataagaaaag cgcagaaacg
     4801 aagccgttat ttcaattagt ctgtcaagga ttggaagagc aaaaaggaat tctagactta
     4861 caagaagaag atgtctatta tattttttct ttgttcaaca gtagaaatta taccaatgag
     4921 aacatggagc tgttaagaaa agatttcgaa gttgtttata aaaattttgt tctcaatgac
     4981 ctatcactga atgaattgat tttacagatt attagtatcg ctgaaatcga cgatgcagaa
     5041 aattttattt tcaagcaatc ctttttacaa tttgtccgta cgttgtgggc agatggacaa
     5101 gtatttttac cggaaaggat ctatcttcta tcagaaaaag aacaacttct gtacggaaaa
     5161 attgtagaaa tattggaaga gtggaaaaag aaaaatcaaa tccaactaag atggaatgaa
     5221 aatttcattc gaaaattcgt caaaagtctt tctttgatca acagtgaaca agcggggaga
     5281 caggaaatag aaatttttgt tgtttcagaa agttcagtca aacaattttt ttatcgaacc
     5341 caatttcatt tgtatgcgga agaaggcatc gctgaaataa atcctatttt atttcgttca
     5401 ttagaagaat tgcctgatga atgtctatgt gcgaaaaaaa gagtggtttt gtgcgatgct
     5461 gctagctatc aaaatggatt agaaactgaa aagacaaaga tctatccaat ctcattaaaa
     5521 ggtgcaaaca tccatttgta tcatattgct caggaacttc acctattaaa aaaacatatt
     5581 tcttgatgag accttaatta ggagaccttc tacaaagctt tttaattgtc tgtagaaggt
     5641 ttttatttga gtcctgattc gtgcgaagat ctacttatat aacaagcttt ctctgaaatt
     5701 tttttaaaat gctattgact tagagtcaac tctaagtagt agaatagata aagtgtaaca
     5761 aatctatttt cattaaaaga agatagtacg gaggagagaa tgtattatga gtacagtatt
     5821 acatgtattg gatgcaatca atagccccgc agatgtcaaa aaattatctg ttgaggaaat
     5881 gaaacagttg gcagaagaga tgcgccaaaa aatcttgcaa aaggacagcg atgtaggtgg
     5941 gcacgttggt ccgaatctag gtgtagtaga attaacgatt gcgtttcatt atgtatttga
     6001 ttcaccaaag gataaaatcg tttgggatgt ttcccatcag tcttatggtc ataagctttt
     6061 aactggtcga aaaaatggtt ttgaaaaagg acattaccgt gaagtgagcg gatattccaa
     6121 ccaacatgaa agtaaacatg actattttac agtggggcac acatctacat ctatcagctt
     6181 agcaacaggt ttagctaaag cgagagatct gaagaaagaa tcaggaaatg tggtagcatt
     6241 tatcggtgac ggctccctaa gtggtggctt agcttttgaa ggattgaaca atggtggtgt
     6301 tttacaatcc aatctaatcg tattagtaaa cgataatgag atgtctattg atgagaatca
     6361 tggcagttta tataaaaact tagctgagct tcgtcaaacc aacggtaaaa gcagcaataa
     6421 cctatttaaa gcaatgggat ttgattatcg ttacgtggat aatggaaacg atctggaaac
     6481 ggtgatccgt ttatttgaag aagtaaaaga tattgatcat ccgattgtac ttcacgtcca
     6541 tacggaaaaa ggtcgcggtt atcagccggc aatcgataat aaaatgaaat atcattggca
     6601 tgtaccattt gatctgtcca ccggggaggc aaagcaagta acttctggag aaacatttaa
     6661 tatgatcatc atggattatt tggataagaa aatgcaaaca agtacagctc ctattgccgc
     6721 agtcaatgca gcgataccag gcgcctttgg actgaaaaca ttccaagaaa aacatccaga
     6781 tcattatttt gacgtgggga tcgctgaaca gcactctatc actttcgctt ctgctttggc
     6841 ttctcaggga gtacgtccag tcgtcttcca atcaagtact ttcttgcaac gggcatatga
     6901 tcaattatca catgatttag cgatcaacga gaatccagtg attattttag tcggtggcgg
     6961 aacgatctca gctagtgacc gaacacacca aggaacattt gacattcctt acttatcaag
     7021 tatcccgaac atcaaatatc ttgctccagc aacaaaagag gatatgatct ctatgctaga
     7081 ttgggcgttc gaacaaacag cgcagcctgt agcaatccga attcctacac atggtgtaga
     7141 acatggtaca gctatcgcaa atgattatag tattccagcc tatcaaacag taaataatgg
     7201 aggaaaagta gcaattttag ctttaggcgg ttttcttgaa ttaggaaaag aaacagtaaa
     7261 agcttttaga aaaaaaggaa tcgaagcaac gttgatcaat ccaggaacga tcacagaaaa
     7321 tgacgtagaa acattagata aattaaaaga aacacacgaa ttagtcatca cattagaaga
     7381 tggtagtttg tcaggaggat ttggcgaaaa tatcagtcgt tattatggtg attcttcaat
     7441 gaacgtatta aattttggtg cagagaaaga attcacggat agcgttcctg tagggcagct
     7501 ttatgaacgt tatcatttaa caccaaaaca aatcgttgaa gatagtctgc gtgtcttgaa
     7561 tattcaataa ttcattatgc tcaccatcca gataattgtt tatactagta tctggatggt
     7621 tttttcatta taaaaagcaa aggggtggat gttatgtatc agcaagtaga agaatatgtc
     7681 aaaaagttcc aagaaaaata tcctagttat caatcagaaa aattaggttt cttttcattt
     7741 ggggatacag aaaaaatggc agacgagttg agcgaactag ttgtaaaaaa gataaagact
     7801 ggtacatcaa gtggttacga tctgtataaa caagagaatg agcctttacc aaaagttggt
     7861 caattagacg tggtcctgaa tggaaaaaat gaaccagttt gtatcatcaa aaatataaat
     7921 gtgaccatct tgccttttag tgaagtcacg aaagagcatg cttggaaaga aggagaaggg
     7981 gatcggacat tagcttattg gcggaaagtc catgctgagt tttttaaaca tgcttataaa
     8041 gaagcgttga acatagaatt tacagaagag aagctggtcg tatacgaaga atttgaagta
     8101 attttctttt agtaagaaag gtctgctgaa agaaatagct cattattgtc tcctgaatag
     8161 aaaagggtta catttttata tgaagctgta tttttatata acattactgg aggagatatt
     8221 gtggatacac tggaacaaat caaaggcgga gtcgtcgttt cttgtcaagc tttggaaaac
     8281 gagccgctac acagttcttt tattatgggg agaatggctt tggctgcaaa agaaggcgga
     8341 gcagttggta ttcgagcaaa tacgacagaa gatatcaatg aaatcaagcg aatcgttgat
     8401 ttaccggtaa tagggattat caaaagagat tacgatgggt cagaagtgtt tattactgcg
     8461 acagaaaaag aagtggaaga acttttggag acgcaagcag aaatcattgc actggatgca
     8521 acttctcgta aacgtccgac agaaaaaaca actgctgaac ttgtccaaat gattcacgaa
     8581 cacggtcggt tagctatggc agatatttcg acttttgagg aagcgcttca agcgcaagaa
     8641 gatggttttg atcttttgtc tacgacttta gcaggctata cagaatattc acgaaagacg
     8701 cagacacctg attttgattt attgaatcaa atcatagaac aagtcgatat cccagtaatt
     8761 atggaaggac atactgactc tcctgaacaa gtagagaaag catatgaatt aggtgctttt
     8821 tcagtcgtag ttggatctat tatcacccgt ccgcaattga tcactaaaag atatgtcgaa
     8881 gccgcaagta aagcaaataa ctaaaaaaca cgcacggcac agattcttga caaaaaagaa
     8941 aaattgatag atagtttaaa gcagattcta agaagatgaa aaaagcatta cttttcattt
     9001 tgtcttcaag atctgctttt taacgaattt tatagaaaga aggcgaaacc atgtttgaac
     9061 ggagtccttc agaattgaca gaacgtgaaa attacaagtt gctgattggt tcagtcatcc
     9121 ctagaccagt agcagtagta acgactaaat cagcaaaaga tatagtgaat atcgcaccct
     9181 tcagttactt caatatcgtc agttcgaatc gacccatctt atccttggcg atccagagaa
     9241 aacaagatgc agtaaaagac acagcaaaga atattcttga gacaagagaa gctgttatcc
     9301 atatccttga tgaggacaac gtagaagaag taaataaaac agcagccaat ctgcctaatg
     9361 aggaaagcga actgtacctg actgacttga ctttaactga ttcagtaatc atttcagtac
     9421 cagcattgac agaagcaaaa gttcgttttg aaacatcctt atatgaacat gtcgagatac
     9481 ggaataaaaa taaagtaaca gctgatttat ttttgctaga agtacagaaa tatcatttaa
     9541 atgaaacagt ctatgatgat aagacaggaa ggatcgatcc aagaaaattg aatgctgtaa
     9601 gccgtttggc aggaaatgat tatgcagcaa taggagaaat tttcacgatt gcacgtcccg
     9661 aataaaaagg agcactagtt atgttaaaaa taagctataa accatcgaca gattcaaaag
     9721 aaatgaaaaa agaatatgaa acagtgaatg attttctgca agggcagtac ttagaagttc
     9781 cgccattgca agaccatttt gtcgttacta ctgttacttt agatggtaag gaaatagaaa
     9841 tgccagatca aacgattagc ggattgttta attactttaa caaataaata tttattccga
     9901 aaagtgaaaa aacatataaa aaaacacata aaactaaaaa attatcaaag aatcctggtg
     9961 caactgaaag aatttgcaac gggattcttt caacttattt gttatttttt tctaaaaaat
    10021 attaaagatt gttaaatttc actatttcat ttcaaattcc attgcctaat cattaggaaa
    10081 agtctatcat gaactcgtaa atagaatata gtaataacct tgttaggtga ggctcctata
    10141 caaacatagg ctgttgccca gaaacgtcga aagtcgccaa tgggtaaaac agaaactgtt
    10201 ggattaaggc tttttccaat agctaagaat gttttcttta cgttgtatag tgctaaaact
    10261 cggacgatga gatgatgcta ggtcagaatt cttgttcgaa aaggtttctg accttttctt
    10321 tatatttttg tgactgactt atttgatgag acaaactcgc tcctcacctg acaagtggat
    10381 tgctgtgtga ggaggagatg cggtgaaaaa agatcgattg gtggattttg ggtccttatt
    10441 tgactttgtc catgatcggt cttttagaag tatacagtgc cagttcttat cgtttattgc
    10501 aagccgatga aaatacaaaa agtctattat tgcgtcaact aattttcata tttttgagtt
    10561 ggagcgtgat cttcttagct cgttcagtca aactacacta tttacttcac cctaaaatag
    10621 caggatacgg tttagcctta tcgattttct ttttagtatt agtaagaata gggatattcg
    10681 gtgtcactgt caacggcgca caacgttgga tctctctgtt tggcattcaa ttccagcctt
    10741 ctgaactggc aaatcttttt ttgatttttt atttaagctg gttttttcgt gacggaaata
    10801 gtagcccaaa agatctaaaa aaaccattcc tgattacagt aggtataact tttctgattt
    10861 tatttcagcc aaagattgct ggagcattga tgatcctttc gattgcgtgg gtcatatttt
    10921 gggcagcggc ggttccattt aaaaaaggga tctatctaat cgttactttt tctgcattgc
    10981 tgattggagc agcaggcggg gtattatatt taggaaataa aggttggctt ccacagatgt
    11041 ttaatcatgc ttatgaaagg atcgcgactt taagagattc ttttatcgat agtcatggtg
    11101 cgggctatca aatgacccat tcgttttatg cactatataa tggtggcata tttgggcggg
    11161 gattaggaaa tagtatcaca aaaaaagggt atcttccaga gacagaaaca gattttattt
    11221 tttcgattat tacagaagag cttgggctaa tcggtgcatt gtgtgtgctt ttcttattgt
    11281 tctcattatg catgagaatc ttttgtttaa gcagtcgctg taaaaatcag caagctggat
    11341 tgtttctttt aggattcgga actttgctat tcgttcagac gataatgaac gtgggaagta
    11401 tcgcggggct gatgccaatg actggtgtgc cattgccatt tgttagctac ggaggaacaa
    11461 gttatctgat cctttcttta ggaatcggaa tcacgttgaa tatttcttca aagatacagg
    11521 ccgaagagtt ggcgctctat cgacctgaaa aacaataaag agaaactgag aaactttcag
    11581 tttgaattat cataaagtac aatcttttat ttttcaagcg agaggttctt ttagaaagag
    11641 gaattcgcaa tgaaagtatc tcaaaaaatc atattatcta ttttgttact gcttacatta
    11701 gtagttggct atttttcgat tgagtttatc catggatttt cgtctgcaaa acagagttca
    11761 actgtgaaaa aggtagagcc gaaaagtatc cctaccacac taaatgtggc tttgattggt
    11821 tcagatgctc gttcgaaaga cgaaaacggt cgctcggatt cacttctggt tgcacaatac
    11881 aaccagaaaa cacaacaagc aaaactgatc tctatcatga gagattcata tgtcgatatt
    11941 ccaggttacg gaatgaataa gataaatgca gcttactctt atgggggagt tgatttatta
    12001 aatcaaacat taaaggaaaa tttcaaattt gaagctccct attatgcaag tatcacattt
    12061 caagatttta tcgattgcgt taatgaactg tttcctggtg gagtcaagat cgatgcagaa
    12121 aaatctctag atttagatgg cgtatatata aacaaaggag agcaagtgat ggatggtaat
    12181 actttactcc agtatgctcg atttcgggaa gacaaagaag gagacttcgg gaggatcaga
    12241 aggcagcagc aagtgatcaa agctatctct cagcagctga aagacgtaac ttcaatattc
    12301 aagctaccca aagcggttgg gaaattactt ggtagtatcc aaacgaacct tccagaaagt
    12361 gtgcttctgg attgtggtat ggatttcctc aaagacatat gttagaataa acaggtataa
    12421 atagtgaaat aaaggaatga caagcaagag aaggaggaaa aaatgaaaag aagtgacaag
    12481 cacggcaaaa atcgaacagg cgcttatatt gccggcgcag tgatcttaat agcagctgcg
    12541 ggtggcggtt atttttacta ccagcactat caagaaaccc aagcagtaga agctggagaa
    12601 aagacagttg agcaatttgt ccaagctttg aacaagggag attataacaa agctgcagaa
    12661 atgacatcaa aaaaggcggc aaataaaagt gcattatctg aaaaagagat cttagataaa
    12721 taccagaata tatacggtgc tgctgatgtc aaaggacttc agatatcgaa tctaaaagta
    12781 gataaaaaag acgattctac ttacagtttt tcatataaag caaagatgaa tacctcatta
    12841 ggtgaattga aagatctttc ttataaagga acattagaca gaaatgatgg tcaaaccacg
    12901 atcaactggc aacccaactt ggtttttcca gaaatggaag gaaatgacaa agtaagcctg
    12961 accacacaag aagcagcaag agggaatatt atagatcgaa atggtgaacc attagcaaca
    13021 acaggcaaac taaaacaatt aggagtcgtt ccaagtaaac ttggagatgg aggcgaaaaa
    13081 acagccaata tcaaagcgat tgcttcctcc ttcgacttaa cagaagatgc tatcaatcag
    13141 gcgatttcac aaagctgggt acaacccgat tactttgtcc cattgaaaat cattgatgga
    13201 gcaacgccag aacttccagc tggagctacc attcaagaag tagacggcag atattatcct
    13261 ttgggtgaag cagctgctca gctgattggt tacgtgggag atatcacagc agaagatatt
    13321 gataagaatc cagaattaag cagtaatgga aaaatcggtc gctcaggttt ggagatggct
    13381 tttgataagg atcttcgtgg gacaacaggt gggaaattaa gcattacaga tgcagacggt
    13441 gtagagaaaa aagttctgat cgaacatgaa gttcaaaatg gcaaagatat caaattgaca
    13501 atcgatgcga aggcacaaaa aacagctttt gacagtctag gaggaaaagc tggatcaact
    13561 gttgcgacaa cgccaaaaac cggtgatctt cttgcgcttg ctagctctcc aagctatgat
    13621 ccaaacaaaa tgacaaacgg gatctcacaa gaagattaca aagcttatga agaaaatcct
    13681 gaacatccat tcatcagccg atttgcgaca ggttatgctc ctggatctac gtttaaaatg
    13741 attacagcag caatcggtct cgacaacggc actatcgatc caaatgaagt gttgacgatc
    13801 aacgggctta aatggcaaaa agacagttct tggggatctt atcaagcaac gcgtgtcagt
    13861 agtgatgtat cacaagtaga cttaaaaact gctttgatct attccgataa tatatatgcg
    13921 gcacaagaaa cgttgaaaat gggtgagaaa aaatttcgta caggcttaga taaattcatt
    13981 tttggtgaag accttgattt gccaattagt atgaatccag cacaaatttc taatgaagat
    14041 agctttaact cagatatctt gctagctgat actggatatg gacagggcga acttctaatt
    14101 actcctatcc agcaagcagc aatgtattct gtttttacca acaatggcac acttgtctat
    14161 cctaaattga ttgcagataa agagacaaaa gataagaaga atgtcatcag cgaaacagca
    14221 gtacaaacga tcgtgccaga tctgagagaa gttgtgcaag atgtaaatgg tacagcacat
    14281 tctctttctg ctttagggat tccgttggca gcgaaaactg gtacagcgga aatcaaagaa
    14341 aaacaggatg taaaggggca agagaacagt ttcttgtttg ctttcaatct tgataaccaa
    14401 ggttatatga tggtcagcat gttggaaaat aaagaagatg atgattcagc aaccaaacga
    14461 gcatcggaac tattgcaata cctcaaccaa aattatcaat aaaaaattgc tttttaagta
    14521 cagtaaaagg actgtggcgt tatcgtcaca gtcctttttt caaataaacg gttttcacga
    14581 tgtctctttc acaacttctt tttgatttac tcacacttca taaacttttt ttgtaaaata
    14641 tttgagaaca agtggagaaa taagtgtact taataaaatc acgataacta aaggtgaata
    14701 gtactgtggt tcgatcaatt gactttgctg tccaatttgt aaaatgatca aagccatttc
    14761 tccacgcgaa atcataccag caccgaccat caatgaacta tgttgagaaa aaccggcaat
    14821 ctgagcacca aaataacctc caagcaattt ggtcaaaatc gctacaagcg tcaatataga
    14881 aataaagagt agttgttcac taaagtcaga aaaatcaact tctaatccta cactgacaaa
    14941 aaatactggt ataaatactg catatcctaa agcctctaca ttgtggtata cttcttcttt
    15001 aacctttgtc tgactgacag ctatcccagc aaaaaaagca ccaatgacag agctaagccc
    15061 aacaagatcc gctacgtaag acattcctaa acaaataact agcgatacga tgataataga
    15121 agaatttgcg tacacttttt ctgcaaatga aagtaggaaa ggcgcaatcc atttgactaa
    15181 taagaaaata aaaacaaaat aaattagctg ttcaatcaaa acaagcggta aagaagcatt
    15241 gctagaagct tcccccgtta gaaaagatag gctgaaactt agaactaaaa cgactaaaat
    15301 gtcatctacc acagaagcac ccaaaattgt tgatccttct tttgtattca ctacgtttag
    15361 ttcttttaat acttctactg aaatactgac agaagttgcc gcaagaataa tcccaaagaa
    15421 aatcgcttca tttcccgaaa cttggaatgc tttgcctgtc aaccagccaa aaacaaccgg
    15481 gaagatgatc ccaagcaaag caacgaacat accaggtcgg aaatattttt tcaaaagaga
    15541 taaatcactt tccagaccag ctaaaaacat taataagatc acaccaatct ccgaaaagtc
    15601 atggactaga atatcaggtt tgacccaatt caatccagct tggcctagca aaacaccaac
    15661 aagtaattgt ccaatcactg ctgggatacc taatctccgc gagatatgtg agccaatcgt
    15721 tgttgaaatc aatatcaggc ataaaatacc aataaattcc attctcatca ttcctttgta
    15781 taaaatatag cccgaactta gcataacata cattattgaa aaaataggaa aatatactca
    15841 caaaaaaacc aacaatccaa aagatttttt tggattgttg gtttttatac ggtctatttt
    15901 aataactaaa aatgattaac gtatagtcat ttttcttatt ctgatgaaat tgataatctc
    15961 ctggatgccc atgaaaatca aaataaagcc gaatatttgg aatagaagca tcaaactttt
    16021 gaatggattg aacaataaga cgaatccgcc aatcaacaac agaatactac tataaacact
    16081 ccaactttta gcttttgtat tcatgctgaa gaacaactgg aacaagctgt tgatgataac
    16141 agctaatcca agaagaatcg gcaggataga aacgattgca ggtgcaaaag catagacgat
    16201 cagagctaag atcaggaaaa aaagaccact gaacagaccg atactccaag aacctgtttt
    16261 ccttttaaaa cggtaagcct caaaaagatt caacaaccca agcaaaacaa gataggcggt
    16321 gatcagataa ccgataaaat gaaaaacagc agaagggttt agcacaatcg caatcccaga
    16381 aataatataa acagcagctc ttaataaggc gtatttttga atattttgtt taatcgtctc
    16441 aaacatataa gaaaacctcc tttgacttat tttaacgtga actagtcatt ttaccaaatt
    16501 aaatgttaca aaatgagcga aggagaagaa tatctctgga aaaatcaact tctgaggatc
    16561 ttttccattt ttttgccttt tgctagctca tcgatcattt tatctaaata acgaatttct
    16621 ttcatcaagt tatcctcgat gtcttctact cgtacaccac aaacaacacc tgtaatcaag
    16681 gaacgtgaag gattggggac aggggcttcc gcaaaaaatt gttcgaaagt cacttgtttt
    16741 tgtagttgat attctagttc tgtttgggaa taacccgtca gccaacaaat gatttcatct
    16801 acttcctctt ttatacgatc ttttctctcc gcttttgcta catacatagg ataaacgctt
    16861 gcaaaacttg tcgtaaaaat acgattttgc gccataatca gtcacctttc tttttttcaa
    16921 attatttact acttatagta tataagaaaa agagaagaaa aagcgattat tcaaaaaaac
    16981 aaaaaggatt gtgacaaaat tcttgtcacc atcctttttt ccgctctctg actttttaca
    17041 atcttcatag ctcaagtgcg catcagataa tcgaatgctc ctaaagctgc agtagctcct
    17101 gaacccattg aaacaatgat ttgtttgtat ggactatctg tacaatcacc agctgcgaaa
    17161 acgccgggga tattcgttgc gccatttttc tcggtcacta tttcatttct tggattcatt
    17221 tcgatcgttc catctagcca atccgtatta gggagtaagc cgactagaat gaatactcct
    17281 gaaacagcta gtgtatgcat ctccatcgta cggcgatcga tataggagag agattctacc
    17341 tgattcgtac cgctgatttc tttcgtcgct gcatgtttga taacagtgac attcgcaaga
    17401 gagactagtt tatcctgtaa gatttgatct gcttttaatt ctggtaagaa ttctagaaca
    17461 tatacatgtt ttgctaaccc agccaaatcg attgctgctt caacaccaga attaccacca
    17521 ccgataacag caatctcttt tcctttaaat aaagggccgt cacagtgtgg gcaataagca
    17581 attcctttat ttttaaactc tttttcgcct ggtacattga tagaacgcgc acctgtcgcg
    17641 atgatggcgg tttttgcttt aagtgatata ccgttagcta agccaatatt aataaaatgt
    17701 tgctctttat ttaaggaaac ggcctgttga ttcatcataa tgtcgatagg gtaactacgc
    17761 acatgacttt ctacttgctg catcaatttt ggaccttctg tgtaagaggt accaatcata
    17821 ttttcaatcc ctagtgtttc aacgacttgt ccgccgaaag aatcagcgac aagtcctgta
    17881 cggattcctt tacgtgctgc atagatagct gcactactag ctgctggtcc accgccaatc
    17941 actaatacat cataaggttc tttttcaaac aactcttctt caatcaaagg gccagtgatt
    18001 ttttcaacaa tttgttcgat cgtcatgcgt ccgctactaa attcttctcc atttaaaaac
    18061 acagttggca ctgccatgat ttttttatca tcgatttctt tttggaacat cccaccttca
    18121 atcatcgtat gagtaatatt tggatttaat acagctaata tattcaatgc ctgtacaacg
    18181 tcggggcaat tatgacaagt caagctaaca taactgtcaa aatgcaatgt ttgtgttatt
    18241 tttttgattt taagactcaa agattcactg attttcggtg cccgtccact aatttgtaac
    18301 atagccagta aaaaagagga aaattcatga ccgaggggga taccagcaaa aacgattcca
    18361 ctttctttgc caactggatt gatagaaaaa ctaggtgtgc gcatcgaatc tcttttttcc
    18421 caagagattt taggagacat ttctgctatt tccttcgtaa attcagctag tttttgacta
    18481 ttttcactat tatccaaact aacagaaaaa acaataggag attcaatcag tgctaaatat
    18541 tgttcgagat tttgtttagt ttctttgtct aacatatcca ccacctaaat ctttccaaca
    18601 agatcaaaac ttggtttcaa tgtttcgcca ctttctttcc attttgccgg acaaacttca
    18661 cctgggtggg tacgtacata ttgagcagcg cgaatcttat caatcagtgc actagcgtca
    18721 cgaccgattc catctgcatt gatttccata gcttgaacga ttccgtctgg atcaataata
    18781 aatgttcctc gctgagctaa tccttgctct tcatccaaaa catcaaaaat acgagaaatc
    18841 tgatgagacg gatcaccgat catcacgtat tcgattttac cgatagcatc tgatgtatca
    18901 tgccatgctt tgtgagtaaa gtgggtatcg gtagagcaag aaaagacttc aacacctaaa
    18961 gatttcaatg tactgtattg ttcttgtaag tcttctaatt cagtaggaca aacaaaagta
    19021 aaatcagctg gatagaagca aagaatactc cagttcccca taagatcttt ttcactgact
    19081 tctaaaaatt ctccttgatg ataagcatgt gcattaaatt cttcgatttt tttcccaatc
    19141 aatgacatag taaaacctcc aataataatt atttatttat aattattgta atttagttgg
    19201 agttgcaaag tcaatggata ttttgttatt taataaagat tactcaaaaa cgaaggttaa
    19261 ttataaaaat agaagaggtc gcaagaaaat gctactgctg gaaatactcg ggataacgtt
    19321 gagtaacagt ttcctgttct ttcagcatca tgtgtaagtg caatcccgtt tgaaatcgag
    19381 cttcttctgg ttttttatca actaaagcct tgagtaaatc ataatgttgt tccatgatcg
    19441 tttcccatgg aagcccctga atggtcactc gtaaccagcg gaaacgttct aaatgggtat
    19501 tatggtcatc taaccagttc caaacttctt ttcttcctgc aatttcgaaa caagcttcat
    19561 gaaataaatt atctgcacgg aaaaaagcgc gttcgtcatt tattttgact gctttttctt
    19621 gttcttctaa aatcgtttct agcactattc gtgtttgtgt gtccaatttg gaacaacatt
    19681 caatcatgat ttgctcttcc aactgttctc ggacaaagcg agcattttct gcagaaacaa
    19741 gattaatttt ggaaacatac gtaccacttt gaggtatcgt atacacgagt tcttgctgac
    19801 gtagttgaat caatgcttcg cgaatgggag tccggccgat agcaagatgt tcctccagtg
    19861 ccttttcaga tattttcctt ccaggttcta agtcagcata gataatttgt ttacgaatcg
    19921 cttgataagc ttgtgattgc aagctgcttt tcatctttat tcctccaaaa tcatttctat
    19981 gaacgtagta taacagaaga ggtctgaaaa acaatctggt atgtcacatt aactagtaaa
    20041 tttgtataaa tagtaaaatt ttggttgaca tagcgatttt tattgcataa aattcacttg
    20101 aatacaaaaa ctaatatgtt agtttaggag gggaaaaatg attgatttaa acaactggag
    20161 gaactttatc cctgaattat ctcaaaaaga agtagaaata cctcattttg accgtgcatc
    20221 attaagagaa aatggacaaa aaaatcctgt ctggatccat ttcggtggcg gaaatcttta
    20281 tcgaggattt catgcagaaa tcgctcaacg tttagcggat ctaggcgaat tgtccactgg
    20341 tgtcattgtt tgtgaaacat tcgatgaaga aataattgaa agggcttacc aagattttga
    20401 tgatttgatt cttgaagtgg tcatgccaag cagtggagag ttcgtcaaac gtatattagc
    20461 tgcgacagct gacagtctgt attgtcatcc agattgttct gaacactttg ataagatgat
    20521 tcgacacttt gaaaatccta gtttacaatt agttactttt gctattactg aaaaaggtta
    20581 tcgattgaaa gatacaaata ataaatatat aggaccgatt gcagtcgata taaaaaatgg
    20641 tccaaagaag ccatcacata caatgagtat tcttgctgtg ctactttata aacgtttttt
    20701 atctggagct tggccgattg cacttgtctc tacagataat ttttcacaaa acggtagtca
    20761 attacgtact tctttgctaa cgatcgcaaa agaatggcaa aaggaaggtt atgtacaaaa
    20821 tacatttatc caatacttat cgaatgaaga aattgttgcg tttccatgga cgatgattga
    20881 tcgtatcacc ccgaatcctt ccttgtcagt tagcaaaatg ttggcaaaag agggcttttc
    20941 aaatatgtcg attttccaaa ccgcaaaagg aaataatatt gctccatttg tcaatacaga
    21001 ggacatccat tatttaatca tggaagatca ttttcccaat ggacgtccga aattcgaaaa
    21061 agctggggta ttcttgactg atcgtgcaac ggtagataaa gcagatacga tgaaggtgac
    21121 gacttgcctt aatcctttgc atacgtcttt agctattatg ggttgtttac tggggtatag
    21181 gagcatagct gaggagatga aagatccaga tttatcgctg ctagtttctg aaatcgggta
    21241 caatgaaggc ctcccagttg tggagtctcc aggtatcatt gatccaaaga tctttctgga
    21301 agaagtaatt actgtgcgct tttctaatcc aaatattcct aatatgcctc agcgaatcgc
    21361 cacggatacc tctcaaaagg tggcgattcg ttatggtgag acgattaaaa aatatatgga
    21421 aatagaagtt aaagacccgc agacacttgt attcatacca ttgactctcg ctgcttggct
    21481 tcgatacctt attggcattg atgatcaagg aaaaccattc atcccgagtc cagacccact
    21541 attgacagac cttcagcata agctttccga tattcaactg ggtacgcaag atacatcaca
    21601 tattcatgag aaaatggctc ctattttgtc aaataaagaa atttttggtg tagatcttta
    21661 ccaagcagag cttggcagaa aaatagaaga aatgttcatc aagatggtag caggaccaaa
    21721 tgccgtacga aaaacattac aggattactt acaagaacat ggaggaaatt tatcatggaa
    21781 atgactttta gatggtacgg atcacaggaa gaaaagatta ccttagatga aatcagacag
    21841 attcctgcgg tcaaagggat tgtaggcaca ttgatggata taccagtagg agaggtatgg
    21901 cctagggaga ggatcaaaga actaaaagaa gaaattgagt ctcgtgggtt aacactaaaa
    21961 gtaattgaaa gcgtcaatgt gcatgatgcc attaaaattg gattaccttc ccgtgagcag
    22021 tatatcgaaa actataagca gacaatccga aacttggcag aatatggaat agaagtcatc
    22081 tgctataatt ttatgcctgt atttgactgg gtgaaatctg accttgacta ccgcttagaa
    22141 gacggctcat ccacgttagc ttttatatct gatgatattc cagatgatcc aagagaaatc
    22201 gtcgcgcgca tcgaacattc cagcaatgaa tttggattgc cgggatggga acctgagcgc
    22261 ttagctccta tcaaatcctt gcttgaagcc tatgcatcag tagacgaaga aaaacttcga
    22321 gaaaattttg cctattttct ccaatcaatc atcccaacat gtgaagaggt aggggtcaaa
    22381 atggctgtac atccagatga tccgccatac tcgatttttg gattagctcg aatcgtaaag
    22441 aatcgagaag atttagattg gttgtgtcgc atagtagaca gcccttataa cggaatcact
    22501 ctttgtacag ggagtattgc agaagatcca gaaaatgatg tatatgggat tttagcagaa
    22561 ttttgccaaa gagatcgaat cccatttgca catgttcgaa atattaaatt tttagctaat
    22621 cgagatttct atgaggcacc acataaatcc gaatacggtt cattagacat gtaccgcata
    22681 ctaaaaacaa tgtatgacaa cggatttaac ggatacatcc gtcctgatca tggaagaatg
    22741 atctggaatg agacaggaag accaggatac ggcttatatg atcgagcatt aggtgctgtt
    22801 tatctaaatg gattatggga agcaatcgaa aaaggaaaca aaagtaaaga taattagtga
    22861 aaaaaactgt aattttatta tgtaaataag aaggatgttc aaattcttga tacataaatc
    22921 cggaggttgt taataagcat tcggatttat gtatcttatt tggtctagga agtaacttga
    22981 ttttcttttt tcgattgatc catgagtgct tcttctttta attcaaagat atattctgag
    23041 atcctcataa tcactttttt ccagtcttct ggtgtgatga ttccttttaa aatatagatt
    23101 tttttgatat gagaaggcaa ttgtttcaaa gggcagtcgc tgataacgat gttgcagttc
    23161 tccataaaat cattttgtat tttgatcgat tcatttgaaa aaatttgttc tatcttaacg
    23221 atcagatctt tactgatata aaaatcacgc gtatagttca caccaatcac aattcgcggc
    23281 tgttttttgt agcgatcata caaatgtact aggtcttcaa ccatccattg cacattttcc
    23341 ttttctaaaa taactggtaa caagtgttga ttttgttctc tgaaatccat ataaaattgt
    23401 tcaatggcgg tttggacttc tttcaatacg ctatgttctt gataaagcat gaaagtagga
    23461 aggggcgtat ttggttgatt gaagttaaga aatccattat aaagtttatt tcgtgcgaat
    23521 gccaatgagt aaagaatctt ttctttttca ggtataaaca aatcaaatac agtacaaagg
    23581 gactccacca tttctcttga ataaagaaca tgaggaacgt ttgctttttt taaaagtttg
    23641 tattgctcca agcttgtttt ttccgattcg attttcgtga tagaaagtcg agctaaaata
    23701 ttcactaaga tgcgttgttc gcgacaaatt ggcagattag gtcgcaaaat atctacagag
    23761 agatcaataa aaaagtcaat atattcatac tctgtgaatt ctttttgtac gtctttcaca
    23821 gaagttgcag gaaaattctc tttacatatt tttaatagaa aatataattt atctatcata
    23881 ccgctattta gtcggtcaag tacttctttt ttaaaaaaag tattcatcat aaaagccact
    23941 acttgcggat cttcatcata aaattctgta gcagtacttg aaaagatgtt ccaataaata
    24001 tctaatgctg catattgaat ttgtacctct tttccagaaa aagactttct gccattatta
    24061 gaaaaggaga tagacaaacc gtactatgct aaaaatgcat taatcttttt cattttcgta
    24121 tacaaataag aggcactata gtttgtttgc tgactgaaac tgataatcga atttgtctga
    24181 cagctgaaca aagaagtcaa gatctgataa ctgactgatt cgttgcagta tcttccaaat
    24241 agacgataat agcagtaagc cggatcaatt ccttcaaaat tcaactttaa aaaaggtttt
    24301 tgcttatcaa tatgcagttc tgttagattg agacgctcaa agtcttgttc taattctttg
    24361 atgtatagta aaaaatttga ttcagacata tggaaatgat ctgctaaata ttgtgtagta
    24421 ataaagaaac gatgttcaga taggaaaaga aaaatatcta attttgtatt gctttttttc
    24481 ttcaagataa acgttttaat cgcttcttga gtttgcatga aagaggctcc tttttactta
    24541 aattgttaaa acttgaaaat attactgttt ttttcataaa tttagacaaa aaaacagtaa
    24601 acatataggt agaatctcta ctatcttatt tcttgcatac aaaaaaatca aggagtgaga
    24661 gagttatgag atattcaacc atcttaatat caacatttgc agccttaagc ttatcgctta
    24721 ctataaatca gacagtccac acagaggaga cagaaacagc caaatggaca gaaaccaagt
    24781 gggccaacgt caatcgaatt acctttcagg atgaattttc atccttcaat tcaggagtcg
    24841 caaaattaag aaaaggacaa acagcgacca tcaaagcaaa aattgactat tcgggagact
    24901 tagcacctat actacaatca gctgttacat ttgagaatgt tgatcccact ttgtcgattg
    24961 gctatgacga gaacactttg actatccaac acaagcaagc gatatttacc ttcaccgtta
    25021 cattaaatca ggacttgtta aaaccagcgc tttttactgt caaggtatca gatggactac
    25081 cgaacgatca tcatttaacg ccgtatagtc agcggcagac aattgagcaa gattcagcca
    25141 tcgactcagg aggagatctt gttgaagaac caacagataa accagaaaat gaaaataagc
    25201 cagaagtacc gcctacagaa aatccagacg gagaacagaa accggaaata gaacctggag
    25261 aagaacccga tacagaaact caaccagagc cagacaataa atcaaaacct gaaataaccc
    25321 ctggagaaaa accagatgta actccagaac cagatacgga ttctggaaac caaacagtac
    25381 cggaaacaaa tccagacaca gataatgaaa ctgaaaatcc agaaaaacca gaggtagatc
    25441 cagaagaaaa accagatgtg actccagaac cagatacgga cgcaagagac caaggaatac
    25501 cagaaaaaat aaacaaaaaa acaattcaag aggatggaaa aaaagagagt aaaaaatcaa
    25561 atctagcaat tctaaaaata aatgaagagc agctgaataa aaaatcacga atatttgata
    25621 gcgcccaatc agctgaaacc ttaaaaagta gcaaggatac aacctttgct gtcctgaaac
    25681 gaaaaataaa cagctaccaa aatccggaga gtcacaaaac aaagttatac tgtggagcgg
    25741 aatcattcta ttaagtatag caacaatgct ttctgcaaaa agatttaaac aaaacagatc
    25801 tctctaacat ttgaataatg tctgtgaacg catttttcaa ataaaaagaa atatccagaa
    25861 aatgacccca aaataccaga ttgaaatctg atatttgggg tcgttcatac tttatctttc
    25921 ttcatattta ttttaaggga tatctgtttc ttttggaaga tggttcggga tctttttcac
    25981 tttcaataca tctaaaaaga aggtaaagat cggaatgccg acaatcaagc cccaaacgcc
    26041 aaagaaccgt tcgctaacaa gtaagaccac aaatgtataa aaaatcggca gttctgtttt
    26101 gctggacatc aacttcggat tcagcacata agactcaatt agatggacaa tcaaaatcgt
    26161 aatcaggata taaacaacat ctcggatgcc tccttgggaa taagctatga aagatagagg
    26221 aatacaagaa atgataacac ctgctactgg gatcagactt aaaatgaaaa tcatgatcgc
    26281 taaactcagc agctgatgaa agccaaatac agccaaggcg attgtagtga gcaacgtatt
    26341 taaaagagcg acaacaaatt gagcttctaa taccaaacca aatgtattga caaacttatc
    26401 ggcaaaatag taaatatctt gaaagaacca agaaaattca ctttttaaaa acaatcttga
    26461 gaatacaatt gtttttttct tttcaatcat aaaaaagaaa cttaagatga atgacatagc
    26521 aaacgccact gccatttttc ctatatcctg taaatagcca agcgcaatcg aagcgccatt
    26581 ttgaagctgt tcaaaaaaat cgtttcgctc aatataagta tggatatatt gtaaaacagg
    26641 atctgcatct tttggctgat gctcgtaaaa attaataacg gactggatca tgtcaaatgt
    26701 ttgatgaata agcatcggga tatactttgt gaatgccaga tagataaggt aaacgatcag
    26761 tgtataaatc atgatagcta aaacacctgt agggattcgg acaaatcgct gaatgatttg
    26821 aacaagatga atcatcaaat aagtaaagat aaatgtgagc aaaatggttg taatcatact
    26881 tctaactaag aaaagaacaa aaacgacaaa taataaaaca gtgagacggc gtattttttc
    26941 attcgccaaa aaacgctgat aaacggtcaa atcgacaacc tccaaataac aaaaaataaa
    27001 cacgttattc attatatgat ggaatatgaa aataagaaag agcaaaaaga aaaaccgcta
    27061 aatgacgtta tcttatgagt tggttttcct cataaaatcg ttcatctagc agtttcagcc
    27121 ctttttctgg tcttgatgaa aattatctag catttttcgg gtcagatgtt gcagtgtatc
    27181 caattcttcc tgttcaagtg gaagataaga cttgatcttt tgtggaatac cttctgcttg
    27241 tttttgcaac gcagcacctt gagcagtcag cgtaacattt acgattcttt catcacccgt
    27301 ttcacgctga cgattaatat aatttttttc tgctaacttt tttagtaagg gagtcagcgt
    27361 accagaatcc agacacaaat catttcctag ctctttcact gaagtctttt tcttttccca
    27421 taaaactaac atcacaagat actgggtata ggtaagattc agcggcttga ggaggggagt
    27481 gtagtgtcta atgatttctt tagaggcggc atataaagga aaacatactt gattaactaa
    27541 atatagatct tccatttttc cacctccgct gttttactat agtgtatcat agcggattta
    27601 cacaaaaaag tctattcact aactgctttc agagtaactt ctatatttcc agctgtagct
    27661 tttgaatacg gacacacttt atgcgctgcc tctaataatt cttgcgtttc ttccagagaa
    27721 agaccttcga tagatccttc aatctctaca cctaagacaa agctcgtttc actttctgaa
    27781 taaagggaaa cttgtgcact gacagtagaa gccccagaga tatttttttg ctgtttgatc
    27841 aattctaatg cactgttaaa acatgcactg aaaccagctg caaacaattg ttcagggttg
    27901 gttgcatttt cgacgcgttt accaggagct gcaatattca attcgaatgt acgatcggga
    27961 ttatgcactt ctccagagcg tccgcctgtg ttgatcattt tcgtagaata catttttttc
    28021 ataaaattac cacctttaat tatattttat acaattgaat tttacacaat ataattgtgg
    28081 aaagcaaaga aatggattgg cataagataa ataagagaaa gcacatgaaa cagacgcgct
    28141 ttctcgaata gcaaacatat acaaaaaata tcagagacaa aaaataatct catcataaac
    28201 attacatata tttctcaaaa agttgttttc tttcttcaaa aattacttca cgatggacct
    28261 gatgaagcat ccataaataa ccaaaaggat ctctgaacat tgagttagtc acaccaaagt
    28321 ccatcatttc tgtcatttct tgaatctcta cacagccatt tcgtaatgct ttattatgtg
    28381 tgtcctcgat atcagagacg atgatattga accagatcgt atttggatgt tcagcagtag
    28441 gagcagtcaa accaagagac gtgttttcat ccagcatatg gaatctcgta ccatacaagg
    28501 taaaaatgac ttcattattg cctctagggt aatctgttgc ctcaatcagt tgtatttcat
    28561 caaagattgt ttgatacagt tctagtgctt tcaaactatc atttaataca aaatcgattt
    28621 ccgttccttt atgcataaag atctcctctc cttttcagtc gaacagttac tagattcttt
    28681 tattatacca gctaaagaaa acgcattcaa aaaaatagcg gatttactta ccaactcatt
    28741 cgattggatg ataagtaaat ccgcgtccca ttacttctgc tacgctgctg acaatgacaa
    28801 aggcacttgg atcgatttct tctatcaatg gtttcattcg ggaaaattca tgatcagtca
    28861 caacgatcaa taaaacctct tttgactttc gattataccc gccttttgcc tctagcaggg
    28921 taaggccacg tccaatctca gcacttaagc gaaggcggat gtcttccaaa taatgttcac
    28981 tcatgaccat aacagatttc tttcgattga tacctgtttc gatataagtc atgacaattg
    29041 aagtgattgc aatagataaa atagcataaa gaaactcttc tattccaaaa ataaacagat
    29101 taagagaaac aacgaatgcg tctgtaaaaa ataagccaat cgaagtattc aagtggaaat
    29161 attttttaaa aatgagggga gggatcgtcg taccgccgct agaagagttg tttttatata
    29221 aaatcgcaac tcctaaagca aaaatcgcac ttccaaaaat gacagacaac aaccgatctg
    29281 aagtaatcat tgtttctgga actattgcaa tgattaaagg aaaaaccaag cttccgaaaa
    29341 gtactttaaa aaagggtttt ttacctaaaa atagaagagc tagtaccaac ataacgatat
    29401 tcaacactaa aataactata gctcggtcaa agcctaaagc agcttccagt aatattccta
    29461 gaccgctgac acctccagca gcaatatgat gaggccctaa aaacatattg atagcgactc
    29521 ctaatatgaa gagggcaaaa ataatcttaa tgtatgtcca tataaattgt ctcgtttctt
    29581 tcatttattc acttccttaa ttcattaata atactcttat cttattataa cttacttttc
    29641 accttaagtt aactttaatt aataaaaaaa ttaggctagt ctaaattatt atgtttcatt
    29701 cttctagaat atacttctac gccaaaaact gttaaaaaac ttttacttta gaaaattgga
    29761 gaaattgatc gcttaagata aattcaggac actaaatagt acaggaagta gactaaaact
    29821 tttaaaagtt ttaagtctat ctatttggca agtttaaaaa ataaaaattc ggtatcaaaa
    29881 aactgttacc gataacattt ttgaaagcgt tgtcttttgc ttctctatca cttatagtga
    29941 tgacgtcata ttaaaacaca aggaggaaat caatggatac agctgcaatt tatcatcgac
    30001 cggaaagtga atatgcattt ctatatacga atacaagatt tcgtattcgg cttcgtacta
    30061 ggaaaaatga tatcaaaaaa gtatatgtgc tatgtggaga tccatatacc ataacaactg
    30121 aaaaatggta tcaaaaacaa cgaccaatga aaaaatgtct aagtaccaat gttcatgatt
    30181 attgggaaat tgaagtgacg agcgaaacaa gtcgcttaca gtatgcgttc catgttgttg
    30241 gggaagataa cacggactgt ttttacggtg atcaaggaat ttttccttat cgagaaaatg
    30301 tgattactga accaaatttt tattttcgaa taccttattt tcatcaaatc gatcgattca
    30361 ctattccaga atgggtaaaa gaaacagtat ggtatcaaat ttttcccgaa agatttgcaa
    30421 acggggacaa agcaaatgac cccgaacaca ctttaccttg gggaagtaaa gatccagacc
    30481 gagaagactt tttcggggga gatttgcaag gtgtgatgga tcatttggat tacttgacgg
    30541 accttggcat caatggcatc tatttttgtc ccatatttaa agccacatcc aatcataaat
    30601 acgatacgat tgattattat gaggtggatc ccgcttttgg cgataaaaaa cttttaaaaa
    30661 acttgattga tgaagcacat aaaagaggga tacgtatcat gttcgatgct gtattcaatc
    30721 atatgggtgt ccattcacca cagtggcaag acgttctcaa aaacggagaa aaatcgatct
    30781 ataaagactg gttccacatc cgttttttcc cagtagattc ttatcagatg actgacttac
    30841 cagaaactgc tgaaaatatc ccatatgata cttttgcttt tactccattc atgccgaaac
    30901 taaatacagc aaatccagaa gtgcaaaaat atttgctgga tatcgcaact tattggataa
    30961 aagaattcga tattgatgga tggcgtcttg atgttgctaa tgaagtcgat catcattttt
    31021 ggaaaaaatt cagagaagca gttacagaaa tcaaaccaga catctatatc cttggagaga
    31081 tttggcattc ctctcaagct tggctgcaag gggatgaatt ccatgcagtg atgaattatg
    31141 catttacaga ttcgattaaa gattattttg caaaaaagaa aatcacagct tcacaaatgg
    31201 tcagtggaat gaatcatcag caaatgcttt acagagatca ggtgaacgaa ggaacattca
    31261 acttattaga ttctcatgat actgccagga tcttgaccct ttgccaaggt aacaaagaat
    31321 tgatgaagtc tgtgatggcc tttatgtttc ttcaaaaagg gtctccttgt atctattacg
    31381 ggacagaaat agggatgact ggtgaagatg acccggattg ccgcaaatgt atgatatggg
    31441 agaaggagga acaagatcta gagctattcg gttttataaa agaacttgtt tctctaagga
    31501 aacagttgtc taagattatt tctgaaggtt ctactcagtg gctaatagta aatgatcgtg
    31561 aagataagct ctatttcaca cggaaactag agggacagat catctatgtt tactttaatc
    31621 agtcaaaaga accttgggta gtagaacagg aaaatgaggt gattcttagt caaaattgtc
    31681 agttgttaga agacgggaaa gcagagatac gacaatacgg atttttgatc atgtgttgaa
    31741 aactgttacc ggtaacaaca agaaagcgtt tgcaaatgaa gatttgtgcc cattataata
    31801 agggtgtaac agcacgttga atacaaagga ggaaatgaag atgaaaaaaa gaagtgtgaa
    31861 acagttgggt ttagggttaa tctctttagg aatcttaggc ggattagcgg cttgtggcaa
    31921 tggtaactct tcagcagaag gggaagccga tgaaggaaaa acgttaacag tttccgttga
    31981 ttctggatat aaagattata taaacgaaat aaaaaacact ttcgaaaaag aaaacgatgt
    32041 gaaaatcaag ctagtagaaa aggacatgtt cgatcagttg gaatcattag cgttagatgg
    32101 gcctgctgga aagggacctg acgttatgat ggcagcatat gaccggatcg gtgcgttagg
    32161 acagcaagga catctggcgg aagtaaaact gggaaatgaa gcagcttacg atgaaacaga
    32221 caaagcccaa gtgacttatg atggaaaaat ctacggagaa cctgcagtaa tcgagaccct
    32281 tgttttgtac tataacaaag atttagtcga tacagcacca tcaacgttta aagatttgga
    32341 gaatctatcc aaagacagtc gttttgcttt tgagtcagaa gcaggaaaaa atacaggatt
    32401 tttagctaaa tggactgact tttattattc ctatggttta attgcaggtt acggtggcta
    32461 tgtatttggt gatgatggca caaatccttc agatatcggt ttgaataatg caggtgctgt
    32521 agaaggaatc tcttatgcaa cagattggtt caaaaatgtt tggccaaagg gaatgcaaga
    32581 cataaaaagt gcaggagact tcgccagcca gcaattcatg tccaataaaa ctgcagcaat
    32641 cattgacggt ccatggcaag cgcaaacata caaagaaaac aatatcaatt atggtgtagc
    32701 caaaattcct actctaaata atggacagcc ttatcaaccg tttggcggag gaaaaggatg
    32761 ggtagtcagc aattatgcta aaaacaaaga cctctctcaa aaatggcttg attatgtaac
    32821 gaatcaggaa aatcaagaaa aattctttga aatggtaaat gaaatccctg caaaccaaca
    32881 agctagggaa acagcaaagg ctaaaaacga tgaattaaca acagctgtga ttgaacaata
    32941 tgaaacagct caagcgatgc caaacatccc agaaatgggc gaagtttgga caggtgcaga
    33001 aaacttgatg ttcgatgcag catcaggttc aaaaacacca aaagaatccg cagatgaagc
    33061 agtaaaaaca atcagtgaag ccatagaaca aaaatactga ttaaaatgat aaccgtccat
    33121 ttttataaaa aatggaacag gtgcttcaga taaaagtggc aagagcgaga tggaaaatta
    33181 tcttgctctt gttgccatta tcttaaaagc agtttgcggt ttagcaagtt tagagggggc
    33241 attcagatgc agcaagataa aacaagcaat atcaacgaaa aaaaaatcac gctttgttca
    33301 cttattccag ggatggggca gtttgtaaat ggccaagctt ttaaaggtat cgtttttttc
    33361 gccatattcg tcctattcat tggtcagatg cttctgggcg gatttcatgc attggtagga
    33421 ttggttactt tgggaagtat accaatggaa gatcattcat tatttatttt gattgaaggc
    33481 actttgcaat tcatcattac aatcattttc ttgatttttt acggtttgaa tcttttagac
    33541 gcttatcgag tagcgaagat gcgtcaagag ggcaaaaaaa tcaatcggac gatgaaggaa
    33601 gtcatacata atataggtga tgaaggtttt ccttatctat tgacacttcc cgcttatctt
    33661 ctcatgattt ttacgatcat tttcccagtc ctagttacat tgttcactgc atttactaat
    33721 tatgacttca atcatattcc accagccagt ttaattgatt gggtaggggc taaaaacttt
    33781 tttagtatct tctttttaag ctcatatcgt aatacttttt ttgcagtctt ttcgtggacc
    33841 gtgatttgga ctttatgtgc aacaactttg caaatcaccc ttggtattct cacagcggtt
    33901 gttgctcacc agaaatttat taaattcaaa cgtattttcg gtatcatttt cttattacca
    33961 tgggcggtcc cagcttttat tactatcatg agtttttcga atatattcaa cgatagcgta
    34021 ggtgccatca atactcaagt gattcctttc ataaaccagc ttccttttgt agatatcagt
    34081 gcaatctctt ggaaaacgga cccgaactgg acgaaagtag caattatctt agtgcagggc
    34141 tggttaggat ttccctatat ctatgtgatg gttacaggaa tcttacaatc gatttcagaa
    34201 gacttatatg aagcagcaaa aatcgacgga gcaaatgcat ggcagcgctt ttcaaacatc
    34261 acgcttcctg ctgtcttcct agtggcagcg ccaacattta ttacacagta tacggggaat
    34321 ttcaataatt tctccatgat ctatctgttt aacaatggcg gtcccggaag cgtaggcgga
    34381 ggagctggtt ctactgatat tcttatttcc tggatctata aacttacgac tggaacttct
    34441 ccgcagtatt ctatggcttc agcaatcacg ttgattatct ccgtcatcgt tatctgtgtg
    34501 tcattgctgg tatttaaaaa gacaaatgcg ttcaatatgg gggattaaca atgaaaaaat
    34561 ttcattcgag tgctcgattc caaaaacgac tttctcactt ttttacttac ttttttcttt
    34621 taatactgtc agtcattatc atctatccgc ttttgatcac agcaagtact gccttcaagt
    34681 caggaaatat tgcagctttt agtttagatc tttcaagtga ctggacttta ggaaacttta
    34741 ctcggctatt cagtgaaaca ctttacggga cttggtataa aaatacattg atcatttctg
    34801 tcctaacaat gatcgtacaa gtgactgtag taactttggc gggctatact tatagtcgct
    34861 atcgttttat cggccgcaaa tcaagtttga tgttcttttt agtgattcag atggtaccga
    34921 ctatggcagc attgactgcc ttttatgtca tggctttctt attagaagcg ctcgataagt
    34981 actggttctt gacaatgatc tatataggcg gtggaattcc aatgaatact tggctgatga
    35041 aaggatactt tgacactgta ccaatagatt tagatgaatc tgctaaactt gatggggcag
    35101 ggcatttcag gatttttttc cagattgtat taccgcttgt caaaccgatg ctcgccgttc
    35161 aagcattatg ggcttttatg ggaccttttg gggatttcat gttagctaag ttcctgcttc
    35221 gaacacctga aaatcagact gttgctgtcg gcttacaaac atttatttct gatgtgacaa
    35281 accaaagagt ctctcttttt gctgctgggg caattttgat tgcactaccg atttgtctat
    35341 tattcttctt tttacaaaag aactttgtta ccggcctgac atctggcgga acaaaaggat
    35401 aggagcagag tatcatgcaa acatttccgt taaactattt ttccgcatta cgtacgccaa
    35461 ctcaagtgtt tgcgggacgc aaactattat catggcctaa atttttcttg atatttgtat
    35521 ttttagtttc cttgatggtc atgcctgtga ctctttttta tgccaatcag atccaagcga
    35581 ttccattaga acaatttcta tccgttcatt cgctgatcga tgaacaagga acccaaaaat
    35641 tttctgaact tgaattatct gaaactgggt tacaagcatc gcaacaaacg atagctgtga
    35701 cccctgaaat tttggtaggt gtgtctttat ctgagaaaca acaatccgat catggaactt
    35761 ttattgattt tgagaaggaa caatgggtga tccaacaaaa ggataaatct ggtatacgcc
    35821 gctatacgat gaattatagc ccatctttcc aaccagattc tgtacgtacg cccgaagatt
    35881 tccaacgatt tttagaaaga gaattttatg ccagtaatcg tccaacaatc attttatctt
    35941 atagtttaag tcttggtctt gtcctatttg tcatgacgag tctcatttta ttcggggctt
    36001 cctttttctt gtggatgaca agaaaaagcc aactttcatc cattcataca ttcaaagaga
    36061 gtgcaaattt gatgctgaat gttatgggaa taggttccat ggcagcagca gttgtagggt
    36121 ttatccactt tgactttatc ttgatgctaa gtgtccaaac aacgataact gtcttgctgc
    36181 ttttatgggt ttttgtcaaa acaagattca aagataagcg tgtcgaatga caagtttaag
    36241 cgatttatgc gacaatgaat gtgaaaaaaa tgaaaaataa agtagttttt gaaaaatttc
    36301 tgaaaaaatt aaacttctta gttgattctt ttctttttta gtattaacgt aatagggtag
    36361 tttttttaag gaggaaaatc atgttagaga aaactttata caatcaatta ttttcacgtt
    36421 ctttctcgct ccctgtcgaa gtaaattatt gggacggtac aacgaaacaa tacggagata
    36481 cggacactcc tccccaaatc aaaatcaata tccatgaaga aatcccaatg aaagagatta
    36541 caagtaacgc atctttggca ctaggagaag cctatatgga tcatcgaatc gagatcgagg
    36601 gaagtatcca agcattgatc aacgatgctt atcagcaagc aaacagcttt ttacgaggaa
    36661 aagattatct aaaatggctg ccaaagaaag aaaaacatac gaaacaaaaa aacaaagaag
    36721 atatccatgc gcattatgac ttaggtaacg acttttataa actttggcta gatccaactt
    36781 tgacttattc ttgtgcttat ttcaatacac ctgaagatac gttggaacaa gcacaaatca
    36841 ataaagtcca tcatatctta gacaaactct ttatcaaaga aggcgaaacg ttgcttgata
    36901 tcggttgtgg ctggggaaca ttgatgttca ctgctaccaa agagtataat gtcaaggcaa
    36961 ctgggatcac actaagtgaa gaacaatacg atttgattac caaaagaata aaagaagaac
    37021 atttagaaga taaatgccgt gtattattaa tggattaccg cgaactaaaa ggcgaaacgt
    37081 ttgatcatat cacaagtgta ggtatgttcg aacatgtagg ttctgaaaat cttgaaggtt
    37141 atttcaaagt ggtaaaagat ttattgaaac caaaaggaac agctttgatc catggaatca
    37201 gccgacaaca aggcggtgcg acaaatgctt ggatcaataa atatattttc cctggcggtt
    37261 atgtccctgg tgttactgaa ttagttgata atattacaaa aaacgatttg caactgattg
    37321 atttggaaag cttacgtcgt gactaccaat tgacattaga acattggaca aagaattttc
    37381 atcaagtcca agatcaagtc acgaaagaaa tgggtgattc cttctatcga atgtgggatc
    37441 tatatttaca agcttgtgca gcttcatttg aatcaagtaa tatcgatgtg attcaatatt
    37501 tgcttgttca acctggaaac aatgacatcc caatgcatcg tgcataattg aggcaaaagt
    37561 actgtttaaa gactatttaa aaagaagcta agttttatga tgctccagaa gtgaactttt
    37621 ttgtctaact tctaggattg tctctaaagc ttagtttctt tttctttata ttttcataat
    37681 aaaagtttgg ttctttaatt tttaaacatg acagaaaatt ttttcttcgt tatacttgta
    37741 atagaatact attttataac aaaggggatc gaatcaatga aaaaaactgt tatttatact
    37801 agtttatttg cagctttgtt tttagctgct tgtcaatcaa ataccaatca aggcacatct
    37861 gggaatacgt cttccagtag cgaacagcgc tcttcacagg tatcggactc ctcaacaaaa
    37921 gcaagcacat cttcgtctag ccagacaaaa agttctagtg aagcaagtac tcagtcagat
    37981 atcaaagtgt ctgcagctcg tgcgatcgaa ttgttccaag ataaataccc agatactgca
    38041 attactagtt tggaattaga tagtgattgg ggatcttact tctacaagat agaaggtgtc
    38101 gatgatcaaa aagaatacga agcaagaatt gatgctcaaa atgaaaaaat ggagacagag
    38161 aatccagaaa ctctagatcg agatgaacaa aatggtcaaa agaaaaaaga agatggtctg
    38221 gatgttgata aattgatcac gattgaggaa gcagcaaaaa tcgccgtcga caaagtagga
    38281 agcggtacgg caacagattg ggatttggat aaagatttag gtactactta ttgggaagtc
    38341 aaagtaaaag acggcaatca aagtacatca gtcaagatca atagccaaac aggcgaagta
    38401 ctgtcaactg aacaagatga ttaagaattt cttcggaaaa caagagttga tttttctttt
    38461 agtcatgata cactagacaa aataacttgt ttgaaggagc gatttacttg agtttagaaa
    38521 cgacctttgc caatcatatc tttgccaatc ctttgatgaa tgcatctggt gtccactgca
    38581 tgactaccca ggaattagat gaactggctc attcagaagc aggagcattt atcactaaga
    38641 gctgtacgat caatgaacga aaaggaaatc ccgaaccacg ctattttgat gttcctttag
    38701 ggagtatcaa ttctatggga cttccaaact taggtttttc ttattatcta gagtatgctc
    38761 ttgcgtatga aaaagtgcag gaaaaccaaa atcaaccgtt atttttttcc attgccggga
    38821 tgagtgtcca ggaaaacttg gaaatgcttg agaaaataga aaaaagtggg tttaatggga
    38881 tcactgaatt aaatttatct tgtcccaatg tgcctggaaa accacaacta gcttacgatt
    38941 ttgaggccac ttatgaaaca ctgaaagaag tattcagcat cttttctaag ccgctaggaa
    39001 tcaaattgcc tccttatttt gattttgctc attttgatca gatggctgat atcttgaatc
    39061 agtttccatt gacctatgtc aatgctatca acagtgtggg caatggtttg tatatcgata
    39121 cagaacaaga agcagtagtc atcaaaccaa aagaagggtt cggcggcatt ggcggagagt
    39181 atatcaagcc gactgctttg gcgaatgttc gcgcttttta tacacgtttg aaaccagaaa
    39241 tccaaatcat tggtacaggt gggattcgga caggacaaga tgcatttgaa catctgctat
    39301 gtggcgcaag catgttacag attggtaccg agcttcataa agaagggccg gaaatttttt
    39361 ctagaatcat aaaagaatta acgcagatta tgtcagaaaa aggatatacg tcaattgacg
    39421 aatttaaagg caaattacgc accatttcat agcaaagaga cgaaggtcat gattgatctt
    39481 cgtctttttt tataaaaaac actcgtctgt tcattcctgt gcaagcgtac tcattgtatg
    39541 ttagacgaac ttgtgggaaa ataacagagg caaaaaggag gataatatga atgatgcaac
    39601 agaattagca aaagagctta aagaaaaaga atttagtttt caagaactag ttacggatat
    39661 acagaaaaaa ataaagaagc aaaatcatga attgaatgcg tttgtcgcgc ttgaaccatt
    39721 cgagagtaat tcccacgagc tattgattcc ccagtcagaa aaagggccat tggctggtat
    39781 cccatttcct ttaaaaatgc tcggtcaaga aaaaaaggga tggctagcta cttcaggatc
    39841 tcgtttattt gaaacacacc gagcttctca tacatctaat tatgtgcggc aagcagaagc
    39901 gataggtcta gttccttttg gacaaaccaa tgcgccagag tttggtttca aaaatattac
    39961 agacccagtc atctatggcc cagcaagaaa cccttggaac cttgaatgta caccgggcgg
    40021 atcaagtgga ggagctgctg ctgcagtttc atcaggaatc gttcctttag ctggtgctag
    40081 tgatggcggt ggttctatta gaatacccgc ttcgttttgc ggattgattg ggctgaaacc
    40141 ttcgcgaggg acgatgccag ttggtccata tgcttggaga ggatggcaag gagctgctat
    40201 tgatttcggc ttgacagttt ctatgagaga cacggaggct ttattttatg ggatgagaag
    40261 tatccattcc ggtgcgccat atcaagtatc gccagttgag tggcaaacac atccaagaaa
    40321 aaaacggttg aagatagctt tttgtgttga ttcaccgatc cactcacaga ttagtgaaga
    40381 ggcagtactt gctgtaaaaa aagctgtaga tttccttgga aaagaagggc atgatttgac
    40441 agagattcct tacccactag atggtcgtaa actgatcacg tcttattatc agatgaatgg
    40501 cgcagaaaca gcagcaatga tccgctcgat tgaaacaggc atccagcgag ctgtcagaaa
    40561 agaagaactt gaacccattt cttggacttt gttccaatat ggtcagaagc tctctgccgc
    40621 tacttacatc gattctctgc atgtatggga tgaagcagca attgtcatgg aaaacctaca
    40681 tcaagaatac gatctattcc tttcaccaac gactgcattt accgccccta aaatcagcga
    40741 agatttgcaa agtgatgcga taagagcaca gatggaacac atcagtgatt gttctgaagt
    40801 agaaggttta gacgttgttt cttccatgtt tgaggagagc ttgaagatca caccttatac
    40861 acagttggct aatctgactg gacaaccagc aatcagcttg cctactcatt tgacaaaaga
    40921 aaacatgcct ctaggaatcc aatttatggc tgccagagga agagaagatt tgctatttca
    40981 aatcggctat ctatttgaag caaatcatca gttccattta ccaaatccat ggaaatagca
    41041 gaaacaagga gaagaagaat gaagaaaaaa agattgtttg ctctaataac tagtgccttt
    41101 tttattttaa gcgcttgcgg tacagctgcc gctaatcagg aagataacag ctggagtaat
    41161 gtagaaaaaa agaaagaatt agtagtagcg acttctggca cactgtttcc cgcatcttat
    41221 tataatgatc aaaatgaatt agttggttat gatgtagatt tggcaaaaga ggtggctaaa
    41281 cggttaaatg tcaaaatctc ctttaaagaa tacaacgtgg atggacaaat cacttctgtt
    41341 tcaaaaagag aatcagattt tgctgcgaac gattttggta tcacaaaaga aagagaaaaa
    41401 aaattctccc tttcagagac tttcaaatat tcatttgaca gtatgatcgt acgaaaaaaa
    41461 gatgattcag gaatccactc acttgaagat cttaaaggga aaaaagcagc tggcgaaccc
    41521 aatactagct atatgcgttt agcggaaaaa cacggagcta aattagtcac atatgacaat
    41581 gccacgaatg atcagtattt aagcgatgta gcaaatggtc gaacagatgt tattctaaat
    41641 gattattatc tgcagaaaat ggccgtatct gctttaccag atatccctgt aaaaatactg
    41701 gagaacgttt atttcaatga aaacgaaagt ggttttttat tgaaagaagg aaatgatgct
    41761 ctgaaaaaga aaatcgatgg cgtattaaaa gagatgaaag aagatgggac gacaaagaaa
    41821 atatctgaaa aatattttca aactgatgtt tcagtcaaac cgaaagaaac gatggctgag
    41881 tcggtgagtg agtgatgtac tttcctctaa ttgatttttc cctcatgtgg acttcacttc
    41941 ctttcgtact gcaaggcttg gtatacacat tagggattgg cttcgtgtcg tttcttttag
    42001 gaaatctggt agggttgctt ttgacagttt taggtctttt ggattggctg cctctgaatg
    42061 tatttattcg tttttattta tcgttcttta gaggcattcc cgcactagtc ctgctgtttc
    42121 tgttatattt tgggttacct tatcaattaa gtgccttaac ggcttcagtc atctgcttta
    42181 cgattaccag cagtgcattt attggtgaaa tctatcgagg atcactagca ggcgtttctt
    42241 caggtcagtg ggacgctggt ttagcttctg gtttttcttt ctttggggta ttgaaatata
    42301 tcgttttgcc gcaagctttt cgaatctcag taccggcact cagtaacgta gctatggatc
    42361 tagtgaaagg tacttcgtta gcagcaacaa tcacagtgcc agaaatattt caaaaagcaa
    42421 agatcatagg cggtcggaca ttcgattatt tttctctcta tattttagtt gcactgattt
    42481 attgggtcat ttgtatcggg atcgaaaaag tgcaacagta tttagaaaaa cgttctatgc
    42541 atcagtcaat ctgaaaaata gaaatggtgc tagcgtggct ggcaccattt ctattttttg
    42601 tttcttgtat attctgccta gtattttaaa accatttcat gtaaaatgta aatcgaaaat
    42661 atgttcggag gtagaaaaca tgaagacccc gctaaccatc gaaatagaat cctcgttata
    42721 ccaatattgc atcgagcaag gcggcttggt tgtagaagaa gtcacgatgc ctgatgacca
    42781 aggaattgta gatacgctta gctgcttgac aaaatttgat ggaagccgag aatggcgatg
    42841 ctatgagctg aaagtgacaa aagcagattt tcgctctaca gccaaactgt catttgttgg
    42901 acattataat tattttgttt taccaagtaa actatatgaa gaagtaaaaa ctgaaatccc
    42961 tacaggaata ggtgttttag tgtatcgtcc gtacacggtt gaagaggaga tgcctgcctc
    43021 tggtacattt ctgattgcga aaaaagcagc aaagaaagag cttgctgtac cggaagaagc
    43081 tttgacaaac cgcttcatgg cttctttatt cagggaagta agaaaagcaa agcaaatgga
    43141 gcgaggcgta aaatattttc caacagatca attgtacaaa gaattgaaaa gacgttcaga
    43201 aaatcaagat ccattttcta acgaacgata ttatgaacgg tttttagagg aaatagctag
    43261 tcaggcaatc aatgagttgc aagaagaagt tatcgcgctt cagcatgatt atgaatattt
    43321 gaggcaacaa cagcagatcc gtcggttgcc tacagagcca ttggagtgaa aaatatgtac
    43381 tatccttatt taagaggaaa acaatttgac ctattagcat taaaagaagc actgtcgcga
    43441 ggattgctct ccaataaaat ccaaccagtg atcgaaccag tacgtgattc cgctacgctt
    43501 aaaaatgtga tcgaattatt tcaaaaaaag caccatcgaa tcgctgtgat ccaaaatccc
    43561 caagtaggac aattcaaatt attcgatcag catgtgcaca gttggacagt caaagaaaat
    43621 agctctgtcg tccctgcaca gatcttaacg ccagaaaatc tcagtgaagt actggattca
    43681 cctccagcgt ttcttgtttt cgatggacag cactacccaa aagatacaga ggtgtggaaa
    43741 cagttggcag gagttgattc gaaatttttg ataccagata ctagtcgctt tcgcatctgg
    43801 ctgcccgaaa acaaaattgt gatccgtgac tcttttcaaa cgagaaagca tgttgaaagt
    43861 tatgcagata aaacagatga cttttttagt gatgactatc tttttttcca cgcagacgga
    43921 tatattggat tttctgattt cacgatcgaa ggtagccgtt atttcgataa agggttccct
    43981 agccgagcgc ttgctatcca tctaacgtat attgatgctt acggcaatat acgcgtgaaa
    44041 cattttgtct ctgacagtaa cgactctgct aaagaccaag cattgaagtt tcttgaagca
    44101 ggagataaaa tgaaaaaatg gatcatgcgt caccatcatc aactcttgat tacttcagga
    44161 atgattgaat tattggctct ttaccagcaa caaaaattcc ctggactggg agtgttgaaa
    44221 aagtggtcac ttatgcatca tttggaactt attagtcacc tgctagatca tccaaaagat
    44281 tggcttaaat attattcaaa agttcaggaa ctatatgaag tgatccaatg attagataat
    44341 gtaaatgaaa aaggaataga aaagaggaaa ctggatgtat attcggcaaa caaggaaaga
    44401 agaagtagaa gaagtggtag aaatcattaa tgccgcagcg gatttcattg cttcgcaagg
    44461 ctctcctcaa tggcaaaacg ggcagaaacc aacaaaagaa acgattttga acgatattga
    44521 aagaaaagaa agctatgtat taatagtgga agatcaaatt gctggaacag ctgcattagt
    44581 ctcaagcgtg gatcccgttt acacaaaaat agatggtagt tggaaagaat caactggtcc
    44641 ttatttatcg attcatcgtg tcgctttagc agaaagtact cgaggaaaaa aactagcaaa
    44701 accgttctta gaacatttgt tgacgattgc agccagcaaa aatatccaag atatccgtat
    44761 cgatacttat ccagctaatg aaccgatgga aaagaccatc tattctgctg gattcactta
    44821 tcaagggatg attgaatttc cttttgaaca cggcgaaaga aaagcatatc aaataatcat
    44881 caattgacta taaaatcatc tgagcaaaga taaagacatt aacactactg aaaaaaacaa
    44941 tcatatgata gccaagaggt tgtaacagaa gtggccagct tcaaaaaaca agaaagaatt
    45001 tccgaaaatg cttctcaaat ttttgtggaa ttttagcgta ttttacgaaa tagctgcttt
    45061 ctgaaactcc cttcatcgag aggtcgtgac atagcttttg tcacgacctc tcggcttatc
    45121 ctacgagtat tattcgatac atttatatca ataatccttt ttttatttta tctgcagctt
    45181 cttggaacgc tccatcgttt gacacgacta aaagtgaggg gatagctttc aaacgtttca
    45241 actgtgctaa atcttctaca taaaccgcca gtctggctga aatctgttca gatgaatctc
    45301 cacgtttttt caggcgcgat tgcaatgttt ctttagagat cgtaataaag ataggacgga
    45361 ctaccgtccc gaaatactca tataaatgcc aaaaaccatt tgctgtcaaa acggcgtaac
    45421 aatttcctac tgtcagtttc tttttaattt ctgctttact ggaaccatat ttatgttgag
    45481 catattggtc ccactctgca aactcatttc ccttgatcat ctgattgaat gtattgtcag
    45541 aaacaaaata ataatcctct tgatcttttt ccccaggtct tggtgatcga ttcgtgtaag
    45601 taatgatctt ttgttccggc tgaaaaatag cttctgcgag tgaagttttt ccagaaccag
    45661 aaggaccgat aaatacatag caataattca ttgtcatttc tcctttgatg attgaacaag
    45721 tgaaaaagct ttggaaaata tttccaaagc ttttaaaagt aactttgctt ttttgtatat
    45781 tataccagca agccagtcac aatagcactt aaaaagctga ctaaagtcgc tgttagcaaa
    45841 attttcaatc cgtgttttgc gacaagattt cctttttctt catttaatcc cttcatcgca
    45901 ccagaaatga tcccgataga agagaagttg gcaaatgaaa cgaggaagac agatataatt
    45961 gctgttgtac gctcagtaaa atggaaatta ccatttgcta attctgtcat agcaacaaat
    46021 tcatttgtaa ccagtttagt cgccatgata ctaccggcat ccactgcttc tttccatggg
    46081 attccgctga tgaaggcaag aggggcaaag atgtaaccta ggatctcttg gaaagtgatg
    46141 ccgaatatcc cgtggaagat agcattgatc atggcaatca aagcaacaaa accgataagc
    46201 atagcagcaa ccgtgatcgc cacatggaaa ccatcaagaa tgtattctcc caacatttgg
    46261 aaaaatgtct gttctttgtt ttcttcaatg atcagctcat cttctttttc ttctaataca
    46321 tagggattta caattgaagc cagaatataa ccgccaaata agttcaaaac aagggcagtg
    46381 atcacatatt tagaatcgat cagtgccata taagatccga cgatcgacat agaaactgta
    46441 gacatagccg atacactcat ggtgaacaaa cgtttctcag ataggaaggg taattccttt
    46501 tttatggaaa taaaaacttc cgattgtcct aaaatagcag aagctactcc attataagat
    46561 tccaatttgc ccatcccgtt gattttactt aatcctagac caacagcttt cataaataat
    46621 ggaagaatct tgatatagcg tagaataccg ataatagcag aaataaatac aattggcatc
    46681 aatacggaaa gaaagaaagg tgcacttcct ttatttgcta caccggcaaa aacaaagtca
    46741 acaccttgcc cagcaaaagc aagaagatga tcaaacattt ttgccaatac agaaacaacc
    46801 gctgtaccaa aagttgtacg taataatacg aaaccaagaa caagctgtaa aacgaacatc
    46861 acaattagtg gtttcaattt gattgctttt ttgttactgc tgatcaaaaa agcaagccct
    46921 aatgtgacaa ataaaccaat aatacctaat aaataactca aataatcact cctattccaa
    46981 attccgtttt attttacctg ttttgcaaat aaaatactaa tctttagtga aattttcatt
    47041 acttttttag agtgaaacgc attcattttc cattagaaaa taaagcgaac aaaataaaag
    47101 gtttaaaaag tgtaacgtct tagtaaagtc tataaaaaaa cgaaactatc gattaagcta
    47161 atagtttcgt tttcaacatt tataagtaaa ctttttctat tggtaatata gattttcgga
    47221 agggtagaca ggtgcgcagg taatatcgat tcctagtttt ttcaatgttt gttcatcatt
    47281 tttattgacc atcacagtag agtgggcttg tgctccctca agttcagcta gtttatcata
    47341 agcaacttga gcgattggat tcgttactgc actgattgat aaagcgatca agacttcatt
    47401 gatgcttagt gcatccaaag aggaatgaag tgtctttgat ttcaatcctt gtattgtttc
    47461 aagaactaat ggtgacaata aaggaatgtc atctgcgata tgggctaaat gttttactgc
    47521 atttaagata actgccgctg acgcatccat caatgaactt gtacgcccgg taatgatgac
    47581 ttcatctggt aattcgattg caatcacagc agaaggatct tttgtaggac tttgcgcttg
    47641 aatcttatct gcatagtcat gggcagggac taccacgttt cggtcttcag gacgtaaacc
    47701 gacttcttcc ataatcagtt tgattcgatt aactgcttct tcgtcgatca atcctttttt
    47761 gaagtcgcat tctgtttgga aataacgacg gatgatttct tgtttagagg cttcttggac
    47821 aacggtatca tccacgatcc caaatcctac acgattcaca cccatgtcag taggagattg
    47881 ataaacagat tctttaccag taattttttc aataatacgt ttgattacag gaaatgtctc
    47941 aacatcccga ttatagttca cagctacttt attgtaggca tcaaagtgga aggaatcgat
    48001 catattgaca tcttttagat cgactgtggc tgcttcataa gcaatgttca gcggatgttt
    48061 caacggaaca ttccatactg ggaaagtttc gaacttggag taaccagctg catgtccttt
    48121 ttggctttca tgatacagtt ggttcaagga agtagcgagc tttccacttc ctgggccagg
    48181 agctgtcact acaacgattg gtttagttgt ttcaatatac tcattttttc caaaaccatc
    48241 ttctgagacg attttttcta cgttgactgg atagtcttcg atttctgagt gtttatagac
    48301 cttgatgttt cgtctttcta gtttattgat aaagactttc gtggcaggct gtccactata
    48361 gcgagtgata acgacactgt tgattaataa gccataacca cgtaattcat cgattaaccg
    48421 caagatatcc atatcataag taatcccata atcaccacgg atcttattac gttcaatatc
    48481 tccagcatag acgcaaatca gtatttcagc ttgatctttc aatttttgca gcaatttgat
    48541 tttcgcatct tcttcaaatc ctggaagtac acgtttcgca tgcttgtcgt caactagctt
    48601 cccaccaaat tctaaatata atttgtcata gtggttcact cgttccaaaa tatacgctga
    48661 ctgctcttca atatattttt ctgaatcaaa accaattttt ttcactaggt tccctcctta
    48721 agtactaaag cattttttca tttttttgag gattcgtcaa ctggaagagc gaaattcctc
    48781 aaaaaaacaa agaaaatggt ttaaaccaac ttgtctagat agttattcat tggtatgata
    48841 gtttttgata aggaaggtgc tacatgaaaa aaagacagaa aaagaaaaac gcatataaac
    48901 actatatccg ttcgattttt accggttatg aaagaatgct tgaagatccc gaattggaac
    48961 aattgacgtt tacttatcta aacgaagaaa cgcagctaac tcgtgatgag catcagcgca
    49021 ttcatttcac aacaagagat ctgcctagta aataaaaaat aagataaagg tcatcggatt
    49081 cgattctgtc ctatcagatg gaaagactag ttgatcgaaa aaaaggctgt accaaatttt
    49141 ggtgcagcct gttttatgga gcattgcccg ctctttttta taacaatttt ttacagaaaa
    49201 tggtactatt gaagtattaa taagtgaaaa acagatgagt aagaggaggc aagtagtatg
    49261 aaagagccag atacaaatgc aaattatgag ccagacgaac tagaggagac gaatgcggat
    49321 caggatacag gacaagaatc gtcttctttt tacgatatca aagaaaaagc aagcatgaat
    49381 ctttcccaat tattagaaga cttacaggct tttgaaaaag ctgtccgcga agaagatatc
    49441 cctgagatct accgtttata caatggccga ttgaatgaag aattaaaaag aagctcaaat
    49501 gaaaatcacg agatcgatca attgctgatg cgtaagatcc atgatcgttt tttacaggaa
    49561 tttcctttta tggaacaagt agaaaacatc tcgccaacga tgagctatta caaaatcggc
    49621 acttattacc atgatcggcc cacggtcggt attgatgcaa gtctgccaga aatttttgtt
    49681 ttgcctaaga tcgatgaaga gtgggagaaa tattcccaac cggagtcaac ggactatgac
    49741 aaaaaaatca atgagctaga cgcaaaggtg atcactgctc agacagaaat tgaacgttta
    49801 gatgaacaaa taaaagaaat caatcgacaa atgactgatt tgaacgacaa taaaggattc
    49861 ttgaatcgta aaaaaatcga ggaagaaatt caagaattag agaagaagaa gcaagtacta
    49921 tctaatgaaa aattaggctg gcttccttat attgagacgc ctgaaacaat ccagcagcaa
    49981 aaagaagcat tgaagcaaga agcaagagca gaccagcttc gtgcagccat cgtagaaaaa
    50041 gaacaaaggc aaatcagacg ctatttcggt agcaaagagg gattcggtca agcaatccat
    50101 gaattcttga tgaattatct tggcaatgag aatcctaata atcaatctaa tgaaggaggt
    50161 tccgagtatg aatgaacacg atgaagcaga atggacaaaa aatgaagaac aaacagaaga
    50221 tcatgaagaa acgaacactt cattggaaga acaaacaagt aatcctctgg atgacacaga
    50281 agaaatccct atgctagagg aaacaaaaat acacgaaaaa gaaaaagtaa ctccgacgaa
    50341 tacgaatact gcagaaaaca cccatgctta cgaaataact gaaaatcccg ggtatttaga
    50401 aggaaaagag caagatcatc aagatatcgt cagtttgatt gaaacagcgg aagcagaatt
    50461 agcggattta cgtatgagaa aagatttgat cgaatcagat tttccacaat tattagaatc
    50521 atatgatcgt tttatattga atgaagaacc aatctccacg atcggaaaga caagcctgat
    50581 cgaatacttc acgtatgaat tactgaaacc gttgaatgat attggtctgg aacggtcaaa
    50641 ttcagcttat gacacatgga aaacaagaca tttttcgatc aattatacgt tgaatggaca
    50701 aaacgaatta gtcttttcct ttgtattacc gaccatcgat caacgatacc aagtggaatc
    50761 gatgagtctc ctaaacgtat caccagagac aatggaaatc aatgtccaag atgaccgggt
    50821 gctttctttg atccgacact ggtcagtgga tcgagtattc tctgcagggc agatcacgat
    50881 attcaatcac aaattgaatc aattattagc ccatgcaaga acacttggtt ttaccgttaa
    50941 tcagacatta ctagacaata cgaagccact tcgtttgaat cttcagagcg aatttgaatt
    51001 gacgaatgaa gtattggatg atatttttat cgtggcaatg aaaaatccat cctacgatat
    51061 ggaaaagatc aacgaaacta cttatcaagt acgattagat aaaggacagt ctttaacgat
    51121 aacaacaaac gaaaaagatc aaacagtctt gtcgatctca tctggagact acccacgatc
    51181 tgtcattgat ttctttatca attacgaatt cttggtccca ttaatggtga gaaagtcctg
    51241 attggataag ttggattacc agatgtcatt cagataattc tgttccaaag gacttgcggc
    51301 agttatccag aataattgtc acaagtcttt tctgtatgta ctaaatggac gtgaataact
    51361 tgctgatgaa ggagggattt cattaggaat gtccacaaat aaaatagcac agcttagctt
    51421 attgtctgct gcttgtgtag caggtaggat cgcttttcaa tttattccga atttccagcc
    51481 aatgactgct atttttttat ttatagtact ttacttaagc ttaaaagatg cgttaattgt
    51541 catgagtctt tctattgcga tcagcagttt ttattttggt gttggaccat gggtcatcgg
    51601 ccaatggatc agctatactg ttgttctgag tttgttttca atcgtctgct tgagaaaaac
    51661 agtgcaaagg aatctatggt taaagggagt ctgttttttt ctggcgggca tggtttacgg
    51721 aataggtatg accgtttttg atacgctgtt atatcgtttg cctcaacctt ggatctatta
    51781 ccttcaaggg gtgtcgtttg atttgatgca cagtataggc aatgttgtgt tctttcttgt
    51841 ttttctgcca gtcgtcaaac gtttttacaa tcattcagga ggaaaaaatg aaaaaaataa
    51901 tttatagttt gcttgcaatg agtgtcagta tactcatttt gacaagttgc agtacaacct
    51961 atacacaatc ggcttccaac caaaaggagg aagtaaaaac atcgcaaaaa gcaacaatca
    52021 cgttacaaga aaatggtcaa aacttttcgg aaaaagaagt gttcttcaaa aaaggcgatg
    52081 atttactgag tattttgaaa cgaaattttg aagtcaaaga agataacggc ttcatcactt
    52141 cgcttgaagg gcactcacag gatgagaaaa atcaactcta ttggatgttt actgtggacg
    52201 ggaaaagtgc tactactggt gccaaagaga tcaaattgaa tgatggacaa tcggtcattt
    52261 tcaatttgtc taaactataa gtttcataaa aaactgttaa agggcgaata ttgccataat
    52321 tcagtgagtt cagttgatga aagaaggaaa ataacatgga aaattttaaa aaaagcggaa
    52381 tgttttccgt aattgctgct ctaggggcta atattctagt tgctatcagc aaatttgtcg
    52441 gctatgcaat cagtggcagt gccgccatgc taaacgaaag catccacagt atcgttgatt
    52501 gcagcaatca gattttgctg ttattcggtg ataaacaagc caataaagga cagagcgagt
    52561 tgcatcaatt tggtgaagga cgagcaaaat actttttcag tacaatcgtc gcaatgatgc
    52621 ttttcttcgg cggtggggca cttggggtga tggaagcttt tgaaaagttg acgcatccat
    52681 cccatgaagt gggtaatccg atcattgtta tagcaatact gttatttggt ttggtaatcg
    52741 aaggaagttc gttacgcgtg gcaatgaaag aaatcaaaga attgaatact gaaaaacttt
    52801 ccacgatgcg ctttttgcgc gaaagtcgac acagtgaaat actgattatt tttacggaag
    52861 acttgtgtgc tgtaatcggt ttggtcttgg ctttagcagg aacaatattg acttatgcaa
    52921 ccgggattgc tgcatttgat gcgatcagcg gattgctgat cggtttcttg ctgatgggag
    52981 ccgccatttt cctagcaaaa gaattttata gtctgatcat cggtgaaagc gtgacagcaa
    53041 gcgatttatc aaaaatcaag ttagcttttg aacgtcctga gatcagtcgg ctgatcgata
    53101 taaaaacagt tcatttaagt ccaacggaga ttttagttgc agcaaaagca gatatcgttg
    53161 gtaacaaaga gaatgaagct tactcggtca tcaatgatat tgaaaaaaat atgcgtcagt
    53221 ctcttcctga caagaagatg tatatataca ttgaaacaga taaatatgac ccaaattatt
    53281 ctcgtaaata aaacgtttat tcatgaattg aagcaaaaat gagaaaaata taatcttgtt
    53341 tttaaataaa acggctacaa tttagcgaat ttatgttaca atgagtccgc tgtttatttg
    53401 ttgtaattaa aggagatatt ttaatgaaca aaaagaaaag tgcgccatgg cttcaagctt
    53461 tgcatgcagt gatgccactt tgtataagct atataccagt aggattagct tgcggagtat
    53521 tgttgcaaaa agttggattt gatcctctct tatcaggact gttatcgatt ctggtctttt
    53581 ccggtggcgc gcagttttta gttgcatcta tgcttacgac gcaagcatca tttgcaacga
    53641 cattattgat ggttttcttt ttagaattac gctatacatt attaggagca agtcttgccg
    53701 gttttatgaa aaaagaaaag cggacgtttt tggctgtctt ttctcaatca ctgaatgatg
    53761 aaaactatgc ggtgaactac ttaaagtttt caactgaccc ttcctggaat aaaagaaagg
    53821 ctttatatgt caattggttc tcaatgactg catgggccgg tagcaatatg atcggtaatt
    53881 ttttcggctc ggtgattcga gtagatgctg accttgtcca ttttgctttg acggccatgt
    53941 tcattttcat gtttatcatg cagatgaaaa gcgcactact gatctttaca ggtttattct
    54001 caggcgtatt aggggtcgta ttcatggtat tattccaaaa tactttcgga ttgattgcag
    54061 caacagtcat tgcttcattt gccggattta tgctggagaa ggcattcaaa aaagaaaaag
    54121 ctaagaaact aagagaccgc ggtaaagatg tcaatgagcc gctcttcaac ttcccggaac
    54181 aggaggccaa tcaccatgac taaactatat ttgctacttt tagttgcttg tctgttcatc
    54241 gtggcatata tcccgcgctt gttcccgatg ctttatttta ctcatcgaaa agtgccatcc
    54301 tggttcagtg actggatgaa atatgtaccg gtggcattat ttgcggcgtt agcttttaaa
    54361 gatgttttca ttactcatga acatctggat attgcttgga atatcaaaat agctgcaatg
    54421 attctagtag caggcgtggc ttacaaaaca cgttcgatgg cgttgtcagt tttgacagga
    54481 cttgcgtctg tctttttgct gtctatgctt taaactgttt tattttatta aaaacagaga
    54541 ttgcgacata agttgttcaa actgatctat ccgaactgca tttgcaacag tcaattctgg
    54601 atgcaagttt attcgtaggg ataaaaaaga ttagtgttgg cttatgatgc aagctctttt
    54661 ttattttagg aattagagag ggatttgtcc ttctatgatt ttttgctata atagggaaga
    54721 tgtttatttt atgaaagaat agttgaggga atttaaatga ataaaaaatt gatgcaagga
    54781 acattttggc taacctttgc taatcttcta tgtaaagttt taggggtagt ctatttgatt
    54841 ccctggctaa gtatgatggg gaacaatcaa gatggtatgc ttgctacgac attgtataat
    54901 gttggctatc ttccttatgg attgttcctg atgcttggta cagtcggatt tccaaatgcg
    54961 attgcaaaaa aagtagctgt agccacaaaa gaaggagata acgctgcttg tcggctgatt
    55021 tttagaagta cgatcaatat catgtttgtc atcggtatcg cctctgctgc actgatgtat
    55081 ttatttgctc ctttactagc cggaatcagt ccgattgcta acgttaataa tgggatacta
    55141 gctatcagaa gtttatgccc atctttgatt gctatcccaa ttcttagtgc aatgagagga
    55201 tatttccaag gaaaaaatga tctgcggcct tatggaactt ctttgattat cgaacaggct
    55261 gtgcgagtga tcgttatctt ggctggtact tattacttgc gcgtattgac tgacggaacc
    55321 atattagaag ctgtattgat cagtacagtc gcttctttct tcggtgggtt agctgcgatt
    55381 atccatatgt atatcgtcgg acgcagaaaa gacttcttcg aacttaaaga ttttttgatt
    55441 tccagccgtt atttcgaaag agaaaaccga tctgcctctg tctctatcat tcgggaaaca
    55501 ctaccgttta tttttgtcgg ctcagtcatt actatcgttc aaatgatcga ccaagtaacg
    55561 atgaaaccac tgcttcactt tttccgtcca gagatcgcag atcagcaact ggaattctta
    55621 ttcagccgtg cttctgtcaa tccaaataaa ttgacattga tcctgatctc catggtagga
    55681 acagtagcta taagcagctt gccaatatta agcacgatga agaaaaaaga tcggatacaa
    55741 atcgaaaaaa cagtaggaga tagtttttcg attgcgttat tgattcttct tccttcattg
    55801 actggaatgt ctttattagc tggaccacta tacacattgt tttttggcta tgatcctgaa
    55861 agtgtcggat atttccaaat ggctttgcta gcttctttgt ttttctcttt attcacgatc
    55921 ctatctacga tgcttcaatc tttgaatcac catcgttttg cgatccgatt aactgtagaa
    55981 gcaattatcc tgaaagtcat cttccaagta atcggattag gattagttgg cggatacggg
    56041 atgagcttat caaatggctt agcattcggt attgtctttg ttcgcggcta tcactttatg
    56101 tgcaaagaat accgaatagc acctttagca aagatcagca attttttctt aaaaactttc
    56161 cgctccaccc tgattatgct tgcagtatgt tttgccgttt tctttttgct gaatcagcga
    56221 ttgtcaatgg aatcaaaaag ctatgcaatg atttattgtg tggctgtagg aagtattggc
    56281 ggcttagtat ttttattttc tcaattcgga aaaaatgggt ttcgaatgtt gaaaaatgtt
    56341 aaacatcata gcagaagcaa agaataggtt aactaatcgt tttttgctgt cacttgaaaa
    56401 acggcaactc gtatgattac gcttgtcgtt tttctatttt ccaattttag tttcatatct
    56461 aatcttactt atgatatagt tataaggtct ggaaaaattc tttgaaacga ggaaattaaa
    56521 cacatgaaac ttgcagtagt tacagatagt tcggcatatc tgccggaacg tatcaagaac
    56581 catcccgact tattcgttat tccaatccct ttgattatgg atgggaaaat ttataacgaa
    56641 ggaatcgata tcgaagcgga tgaatattat ggacttttaa aaaacagtaa agattttcct
    56701 actacttcac aacctgtcgt aggggaagtt ttgggtttat atgaggaatt gaaagagaaa
    56761 gggtatgaca cgattttaag tatccatctt tcttcaggga tttctggctt tgtcaacaca
    56821 ttatttgcga tgaaagatga catcagcgga gtaacggtca ttccttatga ctctaagatc
    56881 actagtatgc cgatgggaca catggtagaa gctgccttag acttaaatga tgaaggtcag
    56941 tcccttgatg aaatacttgc acatatcgat cgaatccgag ataataccta cgcttatctg
    57001 attgtagatg atttgaacaa tttagtacga ggaggacgtt tgacaaatgg tgcagcgctg
    57061 attggcagct tattaaaaat caaaccgatc ctgacatttt ctgaagggaa aattgtttta
    57121 ttcgaaaaaa tccgttcaag taaaaaagca tttgctcgag ctgaagaaat tattggtaga
    57181 agaaataacg aaatacaacc gccagtcaaa ctttacgtga tacatgcaaa taatttagaa
    57241 gtagcgattg cggagaaaga gaaattgcag aaaaaatatc caaatgcaga aatcgaaatt
    57301 ggtcatttcg gaccagtcat tggtacacat ttaggtgaaa aagccatcgg cattgccatt
    57361 tcagcgcaat aattcctttt attcaaaaaa cataccaaaa atattccaac atcatcttgg
    57421 actttctaca tgttactaat gagcgtgtaa aagaacgaga tggtgttttt atttctatca
    57481 atgaagctct ttttctttgc aatcctcact tcaatcctct ataatgtcgc atatagttta
    57541 gtaaatgagt aaactactaa tttacttatt tactaaaaat aaaaggatga ggagttaaaa
    57601 taatggaaat accaacaaat ttaaaacata aaccagtaat cgttgtagaa gactatgata
    57661 aagttgatgg aagaaatgca ttaaatacgg atgcaaaagg gctttcactg ggccttgctc
    57721 agtggaatga tcgtggaaaa gtcgatatct caggcaaggt atggcgacat actggagaaa
    57781 aatggtcacg acagtcggaa gaattaccaa tcacacgtat tttagattta gcgatcttag
    57841 ctgcacaagg aagtttatac ttccaagatg cttatcgtta tgaaaaattt tatgatccag
    57901 aaaatccagt cgtagacatc attggattac aagggaaccg aatgacggta gaagtagata
    57961 ccaaaaatcc aaagatcgat gaagacatca ttttgtatta cgatacacta caaaaagacg
    58021 gagaactgat tggggaacga ttccgtattt taaaacgtct tttagatgag ctaggatatt
    58081 aatagacaga gatgatcaaa aggggaagag aagcatggag aatttctcac taacagaaaa
    58141 ccgaaccttt tcacggctag aaaagcaaat gatctggaag aaaccgaaaa gccatcggac
    58201 aagtgcagaa gaatggcgga tcgcctccga aatcaaaggg aattggcaag atcctgaaat
    58261 gaaaatcagt aacgtacttt tggaaggaga tgccgggtcg gggaagacac aattagccaa
    58321 agcactatct gctgatctgc aacttcccta tacaaaagtg acctgttttg cagatatgga
    58381 caaatcagat gttttcggag ccttattacc tgtagtagat tctaataagg aacaagacca
    58441 agaattacta gaagctattt accaaacaga tacacttgaa gctgtactga cactgatcca
    58501 gaaccattac ggcattgatc ctttttctgc taaagaaaaa ttagcagagc tagttcaaag
    58561 gatcgaagct gattatccag atgcaatcca ttacagctat tacccttctg aaatcgttcg
    58621 agcgattgaa aaaggatatt tattagagat tcaagagccg actgtcatcc gagatgcctc
    58681 tgttcttgtg gcacttaact cagcgctcga accaaatggg atgttgaatt taccgacagg
    58741 aatcattcgt cgccatccag attgcgtcat tgtgatcact acaaatcgaa attaccaagg
    58801 aaatcgccca ttaaatgaat ctttaagaga tcggatgcaa catgcggaaa aaatggatct
    58861 tcctgcctta gaagtcatgg cagaacgtgc gatggcgaaa actatgatcc aaaaacaaga
    58921 acttctctta aagatggcag agattatccg tttgttggat gaaactgcaa aagctaacgc
    58981 catcaaaggt gtagcaggaa tgcgttctta tttttattgg gcaaatacct ataagcaagg
    59041 acaagattta ctccagtcga tttatccaaa agttttgtat aaattatcca ctgattcaga
    59101 tgaattggca attcttgaac aagctttgtc tgacagtgga ttgctactgg aacttcagga
    59161 catattgaga aaagaaaaat ggggtcatcc tcaatctgag catacaaaag gaagaaccat
    59221 tagcgccgaa gaagcaaatg aacgaaacat cactgaaaat gctgaagaaa ttctgcgctt
    59281 agatgaaaag aaatcgttgt ctgctgaaga accaaatgag ggagaagaga aacaagaaga
    59341 aacaatagaa aaaaacgaga ttcctcctca aatgcaaaaa gaacgcagta gcgatatcga
    59401 aggaaaaaat caaaaagaac aacaaacagg agatgattct caagaaatgt ctgcttctga
    59461 catggaagca catgataagg aaatcaagaa gcaactgaat aaagaagcgc gacaaatcat
    59521 gaaggaaacg attcatgaaa aagaaggtct catcgttcac cgaccagctt tccaaggaaa
    59581 aacgccggaa gcacgtgagc tacacatgca agtaatgcca atagtagaat cacttagccg
    59641 gcaaatttta gagttactgg ataatgaaca aacagagacg taccaaaaag gaaaatacga
    59701 aggtcagcgg ttcaatgcaa gcaaagtagc atatggtgat ttgagaaatt ttgacaaaaa
    59761 gaacccgcca catgagcaac cttctttagc ggtagctgta cggatcgatg aatctgggtc
    59821 aatgatacgg gatgatcgga tcgaagcggc aaaaaaagca gcgattgcca ttgccgaatt
    59881 ttctaagaaa gtcgatatcc cattgttgat ttacggagat acagcagacc gttcgtcaag
    59941 agaaaagact tctttgtttt cttataaaga atttgaagac ggatttcaat ggttaaatga
    60001 aaaattagtc actatgaaac caaggcaaaa caatcgtgat ggtgctgcac ttcgtttagc
    60061 agcagaaaaa ttaaacagac aatccgcaac aaccaaactg ttgcttaata ttagtgacgg
    60121 tcagccaaaa gcgttgccgg attatacagg caaaaaagca aaagaagata tccagtctgt
    60181 tttgaaagaa tatgaacgtc aaggaatcct atttgtctcc gcagctattg gccaagacaa
    60241 agaagaaatc aagtcgatct acggtgaaag tcgttttgta gatattactg acttgaatga
    60301 atttcccaag caaatgattc aactgattgc ccgctatcta tgataaaata aagctcaacg
    60361 aacgcactta gcagattcgt tgagcttttc gtttctagtt accggtaaca aggatacttc
    60421 taaaatagaa tcggttataa tcaagaggga ccgttaaagg agtgaaacga tatgatacaa
    60481 gaacaaaaat ggtggaaaga agcagtaggc tatcaaatct atcctgctag tttcaaagat
    60541 agcaatggcg atggtcaagg agacatcaat gggatccgtg aaaaacttaa ttatttgaaa
    60601 gatcttggta tcggctttat ctggatcaat ccgatctatc aatctccatt tgtcgataat
    60661 ggttatgacg taagtgacta tcaagatata gaagagagat tcggaacgat ggaagatttt
    60721 gatttattgc taaaagaagc acatgaatta gggatcaaag tgattatgga tcttgtcatc
    60781 aaccatagtt cggatcagca tcaatggttt gaagaatcga aaaaatctaa agaaagcccg
    60841 tatcgcgatt attacatttg ggtcgacggg gtagatggca aagaaccgaa taattggaca
    60901 tcgattttcg gcggttctgc ttgggagtat tctcatgaaa ctggacagta ttatctgcat
    60961 gtttttgcaa aagaacaacc agacttaaat tgggaaagcg agaaattgaa agaagaacta
    61021 ttcaatatga tccgatggtg gttggataaa gggatagatg gatttcgttt agatgcgatt
    61081 tctcatgtaa aaaaagatga atattcagta aaagccacag agaacccttt ctcacccttt
    61141 caaaatgtct caggaatcga agaacatttg accgatttga aacatgtttt tgaagagtac
    61201 gatatcatga ctgtcggaga agcaagtggt gtcactgcag aagaaggacc acaatgggta
    61261 gggaaagacg gttatttcga tatgatattc gaatttgatc atatccatat ctggcagcaa
    61321 gaaaaagaag ggcaattaga tgtccttaaa ttgaaacttg cattaagcgc ttggcaaact
    61381 tcattggatg gtatcggatg gaacgcttta tatatggaaa accatgatgt tcctcgtgcc
    61441 gtttcagtgt ttggagatac tcgtcccgat ttttgggcta tgtctgcaaa agcaatcgct
    61501 atgatgtatt tctttttgca aggtacgcca tttatttatc aaggacagga aatcggaatg
    61561 acgaatatgc cctttgaatc gatcgatcaa gttgatgcag tagattcgaa aagactttat
    61621 aaaaggctgc ttgcggaagg taagacaaga gaagaagcat tggatatcat tcgtgaaaca
    61681 acgagagaca acagcaggac acccatgcaa tggacttcgg aacaatatgc tggtttttct
    61741 acacatgaac cttggctgat cactaatcca aataccaaaa cgatcaatgt agaacaacaa
    61801 gaatatgaac cagagtcggt cctgcaattc tataagaaca tgatccgcat tagacaaacc
    61861 aataaaggtc tgatatacgg ttcttataaa gaatatcttc atgaacatcc acaactttat
    61921 gtctatgaaa gatatttaga agatgaacaa tatcttatta tggtaaactt aacagaatca
    61981 cttgctgact atgaacttcc aaaagaagca gatcagtcct ggacattact cttgtcaaat
    62041 tcctctagcg gagaatttga agctaaaggc atactagcac cttatgaagc tcggttatat
    62101 aaaacaaaca agtaaaactt cctcgttaaa gttcattagt tggactttgc gaggaagttt
    62161 ttcagattgc tctgtcaatt actcatttca ataattcgct ctaggaccac cgatatattt
    62221 aggacgagag cgaagggctg tcacgtgatc ttgtccaagg gttttcaaac gaggtctgac
    62281 aggtacttgg acatgtttga tatgcatacc gattgatgtg tcaccgatat cgataccggc
    62341 ttgtccaact acgtgttcca cttcgacagg atcattgaac tggtcaaaag cagcaacaga
    62401 acaagcacct ccagcatgta gtgcaggaac aacagagaca atttcgaaat tttttgcttc
    62461 tgccactgtt cgttctacta ctaatgctcg gttcaaatgt tcacaacctt ggacagctag
    62521 cgcaatttct ttaggatcca acaactcttt taacgtacgg atgatccatt gaccaacttc
    62581 cgcactggaa ttttttccaa tatgtcctcc aacgacttcg cttgtgctgc atcctaaaac
    62641 aaaaagatca ccttttttca agtgtgcctc agccaatatg tcattaacta tttcagtcaa
    62701 ttggtctttt aattcttttt ctgacaactt cattttctaa aaccttcttt ttcaattaat
    62761 attgcttccg tgcttgaata cgttgaagac ttgcagttat aggaaaggca agtcccattc
    62821 caatcagatt ttggaagatg tttcctggta tagaagccac tccagccggc caatcatata
    62881 aaatccaacc ggcgatacca tagccgatga tcataactaa gcttcctaat aaaagcccta
    62941 atccccacat acgagtagaa gatttgctga aagaaccagc aacatatcct tgtaacccgt
    63001 ggatcactaa tgaaaaaact gcccactgcg gatatcctga aatcaaatcg atcaatagac
    63061 cactggaagc accaacaact aatccacccg ttggaccata aagaaaagca gcggtataga
    63121 tcccggcctc gcataatgtc acaaatccat tcgtagccgg tacagggatc aaaattgtta
    63181 atgaaagggc aactgtcaac gcaatcagca tagcatagat cgttaattgc ttagttttca
    63241 tttctcattc ctcctttttg aataccgcca gaccagacac ttccggtatg atcgttcatc
    63301 agcacgccat tagaaataca atgggcaaca aattttttac tttctgctac tgctttggta
    63361 aaatctgccc ctaacacaag attcgctgtt attgcagaag aaaaggcaca accggccccg
    63421 tttactgttg tagtgtcgat ttttttatga gaaaatacct cataatgatc aattgaatag
    63481 agaagatcca cagcttcatc tccagccatc cttgtgccgc ctttgatcac aatgtttttt
    63541 gttcctgaag cagtgagttc tttagcgaga tggatcattt ctgttaacga agagggaaga
    63601 gcttgaccag aaagtaaagc agcttctgcc aaattaggcg taatcatcgt aacaagtgga
    63661 aaaagttctt cgatgagctg cgaaatatac aattgattga tcacagcttc agtttctttg
    63721 aatgccaaaa cagggtctaa aatgattggg atattttgtt ttgtttttat gaagtctcga
    63781 acaaccatga ttgcttcact tgaattcaat aacccaattt tgataccatc taatgaagtc
    63841 attttatcaa tcgaaactaa ctgtcgttta agcaattcca aagatataga ttccagcata
    63901 aatcgctcat taatatctag tgcccctata gaagtcaagg cgcttagtcc gaatagacca
    63961 aaattctcaa aagtttttaa atctgtttgg attcctccac cagcaaatgg atcagaaccg
    64021 ccaattgtca agattctttt cataacattt tcctccatga ataagagtat aacgaaattt
    64081 tcaaaaaaga aaaacagcca attggcatat tttcatctca tccaatttaa aaaaacaaaa
    64141 agaaaagaaa gaccaaaatg gatctttctt tccttaaata gttaggactt ttgtgatttt
    64201 aattctttct cgatttgaag ccgttgcact ttcattgtag ctgttcgcgg gattgcatca
    64261 aaatcacgga tgatagggac gttcaagcga ggaagttcat ggacttgctc ccaccatcga
    64321 ttccaatcca tttctttatc aggagctaaa gcaataatcg gttgtggaga atgattttta
    64381 tcccttacaa tcactacttc tgccaaaaaa tctaacgaat ctaataaaaa gtcttcaata
    64441 gctaatgtac tattgatcgt ttcgatcaaa tccacttgcc gatctttcaa aaataggtgg
    64501 ccatgcttat ccataaaacc gtaatctccg ctatcccacc aatcgccata aacattttcc
    64561 tggaaccgtg catcttcctt gtaataagtc aaagcccgtc ctttagacag taattgtata
    64621 tgaccatctg tgttttcagg taggacattc ccaactgaat ctgtaatccg agcgcttgtc
    64681 atgtcttcca gtccaacgcc catatctctt gcatcacttg ttttcaaact ctctagtgta
    64741 tgagccttaa gaatcattgg tccgcattca ctttggccat atacttgaag aaataccgca
    64801 tcctgtgcca tcgacgttcg caaaaatgtc ttcattgtct ggttgtttat agcatcaaaa
    64861 gtggagtgat agtatcggat acccgaaaaa gcttctggat gctccttagc agtaaaacgc
    64921 cactgaacaa agttattcgg atgggtctct agtgcaattg gccggtgagc ttccaacata
    64981 tgaacaactt ttgaactttg tgcgtttgct aaaggcatca taggaaatcc catggacatc
    65041 aaagaagaga taccaatatt gaatctggaa tgcactggag agatgtgaaa agcgattaat
    65101 ttcttttccg aaatttttgt gaaaactgtt ttttgccatt tcgtccgcca tcccatagaa
    65161 tgagcagaat gacaaataag tttagggata ccagttgtac cagaagtatg ggtcatataa
    65221 gaaatttcat ttttgtctaa aaatgattga gaaacagaca aagcaggttg ttccattaaa
    65281 taaagaatag g
//
LOCUS       DBBGRF010000010        61922 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000010 DBBGRF010000000
VERSION     DBBGRF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 61922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61922
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.010"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            45..1412
                     /gene="nhaC"
                     /locus_tag="ACIZD4_000723"
     CDS             45..1412
                     /gene="nhaC"
                     /locus_tag="ACIZD4_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HGC5989677.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1693..2712)
                     /locus_tag="ACIZD4_000724"
     CDS             complement(1693..2712)
                     /locus_tag="ACIZD4_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5989678.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2734..3741)
                     /locus_tag="ACIZD4_000725"
     CDS             complement(2734..3741)
                     /locus_tag="ACIZD4_000725"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGC5989679.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3734..4399)
                     /gene="pgmB"
                     /locus_tag="ACIZD4_000726"
     CDS             complement(3734..4399)
                     /gene="pgmB"
                     /locus_tag="ACIZD4_000726"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HGC5989680.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4392..6686)
                     /locus_tag="ACIZD4_000727"
     CDS             complement(4392..6686)
                     /locus_tag="ACIZD4_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HGC5989681.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6946..9111
                     /locus_tag="ACIZD4_000728"
     CDS             6946..9111
                     /locus_tag="ACIZD4_000728"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGC5989682.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9415..10248
                     /locus_tag="ACIZD4_000729"
     CDS             9415..10248
                     /locus_tag="ACIZD4_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGC5989683.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(10350..12050)
                     /locus_tag="ACIZD4_000730"
     CDS             complement(10350..12050)
                     /locus_tag="ACIZD4_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989684.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12557..13717
                     /locus_tag="ACIZD4_000731"
     CDS             12557..13717
                     /locus_tag="ACIZD4_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC5989685.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13733..14176
                     /locus_tag="ACIZD4_000732"
     CDS             13733..14176
                     /locus_tag="ACIZD4_000732"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5989686.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14659..15189)
                     /locus_tag="ACIZD4_000733"
     CDS             complement(14659..15189)
                     /locus_tag="ACIZD4_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HGC5989687.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            15294..15845
                     /locus_tag="ACIZD4_000734"
     CDS             15294..15845
                     /locus_tag="ACIZD4_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC5989688.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15998..16471)
                     /locus_tag="ACIZD4_000735"
     CDS             complement(15998..16471)
                     /locus_tag="ACIZD4_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC5989689.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16609..18081
                     /locus_tag="ACIZD4_000736"
     CDS             16609..18081
                     /locus_tag="ACIZD4_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HGC5989690.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            18078..18788
                     /locus_tag="ACIZD4_000737"
     CDS             18078..18788
                     /locus_tag="ACIZD4_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HGC5989691.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            19140..19424
                     /locus_tag="ACIZD4_000738"
     CDS             19140..19424
                     /locus_tag="ACIZD4_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HGC5989692.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(19741..20124)
                     /locus_tag="ACIZD4_000739"
     CDS             complement(19741..20124)
                     /locus_tag="ACIZD4_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HGC5989693.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(20126..20710)
                     /locus_tag="ACIZD4_000740"
     CDS             complement(20126..20710)
                     /locus_tag="ACIZD4_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HGC5989694.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(20757..22232)
                     /locus_tag="ACIZD4_000741"
     CDS             complement(20757..22232)
                     /locus_tag="ACIZD4_000741"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HGC5989695.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            22413..22724
                     /locus_tag="ACIZD4_000742"
     CDS             22413..22724
                     /locus_tag="ACIZD4_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989696.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(22839..25175)
                     /locus_tag="ACIZD4_000743"
     CDS             complement(22839..25175)
                     /locus_tag="ACIZD4_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HGC5989697.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            25317..25985
                     /locus_tag="ACIZD4_000744"
     CDS             25317..25985
                     /locus_tag="ACIZD4_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC5989698.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            25988..27031
                     /locus_tag="ACIZD4_000745"
     CDS             25988..27031
                     /locus_tag="ACIZD4_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5989699.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(27268..28149)
                     /locus_tag="ACIZD4_000746"
     CDS             complement(27268..28149)
                     /locus_tag="ACIZD4_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC5989700.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            28308..29036
                     /locus_tag="ACIZD4_000747"
     CDS             28308..29036
                     /locus_tag="ACIZD4_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HGC5989701.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            29192..29509
                     /locus_tag="ACIZD4_000748"
     CDS             29192..29509
                     /locus_tag="ACIZD4_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC5989702.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            29502..30110
                     /locus_tag="ACIZD4_000749"
     CDS             29502..30110
                     /locus_tag="ACIZD4_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGC5989703.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            30165..30956
                     /locus_tag="ACIZD4_000750"
     CDS             30165..30956
                     /locus_tag="ACIZD4_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HGC5989704.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            31094..31582
                     /locus_tag="ACIZD4_000751"
     CDS             31094..31582
                     /locus_tag="ACIZD4_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HGC5989705.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            31633..32505
                     /locus_tag="ACIZD4_000752"
     CDS             31633..32505
                     /locus_tag="ACIZD4_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGC5989706.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            32681..33043
                     /locus_tag="ACIZD4_000753"
     CDS             32681..33043
                     /locus_tag="ACIZD4_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC5989707.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            33052..33804
                     /locus_tag="ACIZD4_000754"
     CDS             33052..33804
                     /locus_tag="ACIZD4_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989708.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            33818..35620
                     /locus_tag="ACIZD4_000755"
     CDS             33818..35620
                     /locus_tag="ACIZD4_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989709.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            35897..36937
                     /locus_tag="ACIZD4_000756"
     CDS             35897..36937
                     /locus_tag="ACIZD4_000756"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGC5989710.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(36989..39133)
                     /locus_tag="ACIZD4_000757"
     CDS             complement(36989..39133)
                     /locus_tag="ACIZD4_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC5989711.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(39490..40863)
                     /locus_tag="ACIZD4_000758"
     CDS             complement(39490..40863)
                     /locus_tag="ACIZD4_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC5989712.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(40863..41258)
                     /gene="rbsD"
                     /locus_tag="ACIZD4_000759"
     CDS             complement(40863..41258)
                     /gene="rbsD"
                     /locus_tag="ACIZD4_000759"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HGC5989713.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(41286..42203)
                     /gene="rbsK"
                     /locus_tag="ACIZD4_000760"
     CDS             complement(41286..42203)
                     /gene="rbsK"
                     /locus_tag="ACIZD4_000760"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HGC5989714.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(42311..43324)
                     /locus_tag="ACIZD4_000761"
     CDS             complement(42311..43324)
                     /locus_tag="ACIZD4_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGC5989715.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(43405..44004)
                     /locus_tag="ACIZD4_000762"
     CDS             complement(43405..44004)
                     /locus_tag="ACIZD4_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HGC5989716.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            44190..44891
                     /locus_tag="ACIZD4_000763"
     CDS             44190..44891
                     /locus_tag="ACIZD4_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989717.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            44901..47612
                     /locus_tag="ACIZD4_000764"
     CDS             44901..47612
                     /locus_tag="ACIZD4_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGC5989718.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            48063..49691
                     /gene="treC"
                     /locus_tag="ACIZD4_000765"
     CDS             48063..49691
                     /gene="treC"
                     /locus_tag="ACIZD4_000765"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGC5989719.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(49751..50932)
                     /locus_tag="ACIZD4_000766"
     CDS             complement(49751..50932)
                     /locus_tag="ACIZD4_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC5989720.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            51184..52707
                     /locus_tag="ACIZD4_000767"
     CDS             51184..52707
                     /locus_tag="ACIZD4_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HGC5989721.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(52776..53504)
                     /locus_tag="ACIZD4_000768"
     CDS             complement(52776..53504)
                     /locus_tag="ACIZD4_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGC5989722.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(53517..54797)
                     /locus_tag="ACIZD4_000769"
     CDS             complement(53517..54797)
                     /locus_tag="ACIZD4_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGC5989723.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(54938..55540)
                     /locus_tag="ACIZD4_000770"
     CDS             complement(54938..55540)
                     /locus_tag="ACIZD4_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HGC5989724.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            55785..55991
                     /locus_tag="ACIZD4_000771"
     CDS             55785..55991
                     /locus_tag="ACIZD4_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989725.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            56303..57022
                     /locus_tag="ACIZD4_000772"
     CDS             56303..57022
                     /locus_tag="ACIZD4_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HGC5989726.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(57103..57786)
                     /locus_tag="ACIZD4_000773"
     CDS             complement(57103..57786)
                     /locus_tag="ACIZD4_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGC5989727.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            58005..60191
                     /locus_tag="ACIZD4_000774"
     CDS             58005..60191
                     /locus_tag="ACIZD4_000774"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HGC5989728.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            60537..60947
                     /locus_tag="ACIZD4_000775"
     CDS             60537..60947
                     /locus_tag="ACIZD4_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC5989729.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            60961..61317
                     /locus_tag="ACIZD4_000776"
     CDS             60961..61317
                     /locus_tag="ACIZD4_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC5989730.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        19821 a        10984 c        12505 g        18612 t
ORIGIN      
        1 ttttttcatg gcagggcctt ttcatttgaa ataggagatc gacgatgaat aaaaatattt
       61 ctttaaaaga aagtatcgct gtattgatcg tgttgttggc actcctagga gtactgatca
      121 tcggattcca gctctcgcca catatcccga tccttgcagc tttcatgtgt ttgttgtttt
      181 atggcagatt taaaaagttc acatgggatg agatccatga cgggatcatc aaaggaatca
      241 ctccagggat cattccaatc ctgatttttc ttttgattgg tgtcttagtt gcttcatgga
      301 ttttatctgg aaccatccct acgattatgg tttatggatt taaacttgtt tctgtgcgtt
      361 tctttttacc gacagcattt cttgtttgtg caattgtcgg agtgactgtc ggcagttcat
      421 ttacaacgat ttcgacgatt ggaattgctt ttttggggat cggtcattta cttggattca
      481 atgatgcaat gactacaggc gcagtcgttt ccggtgcctt tttagggaat aactgctcgc
      541 ctttatcaga tacgaccaac ttggcagcgg gtattggagg agttaatcta ttcgaacata
      601 tcgctggtat gcgttatacg gatttcccag cattcgtcct ttcgttgatt ttttatacga
      661 tattaggaca taacagtcat tcagccgatc tagctagtat caatgaaatg atccaaaaca
      721 tgaaagcgag cttttggatc tctccttgga cattgattcc actagttatt ttatttgggg
      781 gggcaatcaa aaaaattccg gctatcccta cattactagc gggatcgaca gctgctctcg
      841 ttctttcttt tatccatgag aaaagtttga cggtcggaaa agcagcagac atcttgatga
      901 atggttatgt cgcaaataca cctgatccaa agctagatga actgctttct cgaggcggga
      961 tcatgagtat gttaggttct gctagtttga ttttacttgc attggcatta ggtgggttac
     1021 tgatcaaata tctgatcgtt gataccatcg ttcaagaatt aaaagaaaag atggaccgac
     1081 cttctcgttt agtcgggttt actgccttga gctgtatcgg aatcaatctg atcgttggag
     1141 aacagtatct gtccatcatt cttccaggag aaacattcaa gcgttctttt gatgacgttg
     1201 gcttatcaaa aacctatttg acacgaacac tagcggattc aggtgcgacc gtcaattctc
     1261 tcgtaccgtg gggagtcagc ggcacattca ttatgggaac gatgaaagtt agcgcgttgc
     1321 attacttgcc attcgccttt ttctcgattc ttgcacctgt ctttacaata ttaggcggtt
     1381 ttttattgaa tcgtcgacgt gtaaaaaatt gaaggaagga aaaaagaggc tgggacagaa
     1441 gcgtttaact ccaagaaata agaagaaact caagaaaatt gctttttaaa tttttgtgaa
     1501 tttcagctta tttccgaagg agttgcttct gcttccgccg tttatacgtg tttagagcgt
     1561 gagacaaaag tgttctttac ttttgtccca cgctcttttt tacagataaa caatgtgtta
     1621 gaagtagtat cttcttttac ataaaaagct gaccatagga taaatggtca gcgtatttag
     1681 tgagtcagct atttagtatg ggttttctaa aggaacgact gtctctcttt tgatcaagcg
     1741 atgagggatg accaaacgta cgccactgct caattcttca tggatcaatt cgcgcagctt
     1801 ttgcatagcg acacgtccta attcggagat atcgatatcg atacttgtaa ggtaagggtg
     1861 tgttaatgtt gagaagatcg agttgttgaa gctaatgacg gagagtgtct ctggaatgac
     1921 atagccatac atttgcgcca actgcatcgt gcgaagggcg aagatatcgt caatgaccac
     1981 caatgctgtg gcttcgtttt ctttcaacgt tttctcaaag gacagataat cctccggatg
     2041 ctctagtact acactggata acgcaggaag accagccatc atcattgctt tttgataacc
     2101 gaaatatcgt tcgaaataca aactttcatg agtcgtgttt gtcacaaaca ggatattctt
     2161 atgtccattc tggatcaaaa attctgttgc ttgtttacct agaagctggt tatcattatc
     2221 tacataaacg atttcgttct catgatgata aggctgtccg atcaaagtga aagggatgtg
     2281 gttttggtat aaataatcaa tgacagtatc ttgactatct gaatacacta gaataaaacc
     2341 atctacttgt ttttgtaaat gcatacgctg gacgttctct aacagcaatt caaaattttt
     2401 agcagtagcg attgctgtag tcatatcata attccgcgct tcttcgttga ttgcttccat
     2461 gatctcaaga taaaatgggt taccgatccg ctcttttgaa tcaagagggg gtaagattac
     2521 gccgatggca ctggaaatgc gttttcctag attgcgggca gtcatgttag gaacataacc
     2581 tagttcatcc ataatttttc ggactttctt ctttgttgtc tcggaaatac taggatgatc
     2641 gttgatgaca cgagagacgg tcgaggtggc aacaccggct tttttcgcca catcttttac
     2701 ggtaatagcc atgataaaaa cacctttctc ttgttattgt gcagagaacc gataaatcgt
     2761 ctgactgatc cgttcttgac caggatggag gttgatcgat ccaaatttgg ggaaatgaac
     2821 gatatcaggg atttcttgcg gttcgattgc taatccgtag tttgaatgca tctgttttcc
     2881 attgacagag aaatcagctt cgaatccagt cgtagaaaat aataccatac ttttattaga
     2941 agttgctata gtcatttggc gaccagaatg cttctcgaat aattgtaagg aagttttgga
     3001 aagcctagga tgatgcaaaa gaaatacatc atctagtcca tctggataac atgcaaggat
     3061 ctcttgcagt gttggggatt ttctaaagtc gattggcagt ttttcttttt ttgtccaatt
     3121 tccagtaggc agtttttctt gatctaattc aagcacacca tctaaaaaga ccgttaactg
     3181 atgttcatag atgtctcttg ttccatttcc tgaaaggttg aagtaggcat ggttggtcgg
     3241 attgcagatg gtttcaacaa ggctactagc agaggttgtc atctctaatt cgttttttgt
     3301 taaacggtaa gtgatcgtag cagtgattgg tcctggatag gtagaaaatt catcttttaa
     3361 gtaaaagacc acacctattg atgatggagt tttgaaaact tctacttccc aaaattggaa
     3421 agaccagcct ttcgtgccac cgtggatatg gtgtgatccg cagtttttct ccaatctatg
     3481 ctcaccccaa gaagcatccc ggatccttcc ggctacaggt ccgacagttg ctccaaaaaa
     3541 gcttttgtct gttagaacat cttcgaaacg atcgtaagac aataaaacat tttctgattt
     3601 tccttctttg tctggtgcga agatttggtg caggcgggca ccgtaattga gaagaacgac
     3661 ttctaagtag tcgttcttca atgtgatttt ctttatttca gtctctggaa ctggtacgac
     3721 ggagatctct ggattatcca tggtcatgcc acttttcttt caagtaatcg atcgtaagaa
     3781 aagtcgtatc agggacaagc gggatctcct ctccaaggtc ttcagcacgt cccacgccaa
     3841 ttggttgagc gccacttgag aggatggctt ggataccggc ttgcgcgtct tcgatcccga
     3901 tacattcttc tgcttttagt ccgacagctt ttgctgcaag gaggaagata tctggcgcag
     3961 gttttccgtt tgttgcttct gccgggtcgg caatagcatc aaagtaaggt gtaagaccca
     4021 ttttttcaag taggaatggc ccgtttttac ttgcagaagc aagagcaatc ttgatttttt
     4081 cttcttttaa agaatccagt aaaggcacga ccccggggaa gacatctttt ggttcgatcg
     4141 tctggatcat ctctaaataa taatcgtttt ttcttttcgc taattctgca aattcttcct
     4201 ttgaaaaaga gtgttctttt ccgccataag ctaaaagcaa agagagtgag tcttctcggc
     4261 tgacgccttt tagctgttcg ttgaatgtgt ggtcgatcgt aatgccgatt tcctgaccaa
     4321 gctttcgcca agcacgataa tggaattcag cagtatcggt aatgacaccg tctaaatcaa
     4381 acaatacccc tttaaacatt tgcttcctcc tttcttagcg ttatttctag acgatccgct
     4441 aaagaataag actgttcata gacgtaaatt tctagaggag aaccttctaa taactcgaaa
     4501 gtaacttgtt catctgtgac tgagatgaac aataaacgtc cgcgataatt gatatggaaa
     4561 gaataagctt tccaagtttt tggcagaaat ggtgcgaatc tcaactgatc atgggcagtt
     4621 ttcatttgag caaatccttg gacaatcgac aaccagctac cagtcatgga agtgatgtgc
     4681 aagccgtctt ctgtgtcgtt attgtaatta tccaaatcca agcgagctgt tcgctggtac
     4741 atttctacag ctttgctttc cattcctaat tctgctgcta aaatcgaatg gatacttggc
     4801 gaaagggaag actcatggac agtcattggt tcatagaaat caaagttttt ttgcttttct
     4861 tcttttgtaa aagtatcatt gaagaaataa atcccctgta gtacatctgc ctgcttgatg
     4921 aagcaagatc taaggatttt gtcccaagac caatgctgat tcagaggaag atcgcttgtg
     4981 ggaatatcgg atacaggcat gagatcttta tctaagaatg tgtcatgctg gacaaagatt
     5041 cctaattctt cgtcaactgg gaagtacatg ttctctgcga tatctttcca tttggctagt
     5101 tcttcttcgc tgatagtgat agcagcttct ttttgataag ttaaataatt ttctcgcgtg
     5161 taacgcaaga cccaagctgc gatcgtattt gtataccaat tgttattgat attgttctca
     5221 tattcgtttg ggccggtcac accgtggatc atgtatttat ttgctcgttt tgaaaaatgg
     5281 acacggtctg cccagaagcg tgcgatttct gctaaaactt ccagtccttc atttttcaaa
     5341 tattccgtat cgccggtgta attcgtataa ttgtagattg cataggcaat cgcgccattt
     5401 cggtgaatct cctcgaatgt gatttcccac tcgttatggc attcgacacc agtgaaggtg
     5461 accataggat aaagcgcgcc ttttaatcct tgttgctgag cgttgtggat tgcttgcggc
     5521 agttgattat gccgatattt cagcagattc ttagttactt caggtttggc taaagcaaga
     5581 taaagaggga cagcatacgc ttctgtatcc cagtaagtgg ctccgccgta tttttctcct
     5641 gtgaatcctt tggggccgat attcaatcgt tcatcttcgc cgtagtaagt agagaatagt
     5701 tggaacaaat tgaatcgaat accttgttgt gcttcttcgt ctccttcgat gaccacatcg
     5761 gcaagcttcc atcgttctgc ccaagccgct gtttgctctt cttttgcttg gatataattg
     5821 tttgtctggt tcgttaattc tgagacagct ttttctgctt gctgcgcttc tggaatatct
     5881 ctactagtaa gaacgataat ttctttttcc actgaccatg tctcaccttg agataattct
     5941 gcagacaagc aaccatgtaa tgctaaagta tcttcgtgat agtcagggat gactgatttt
     6001 ccattaacga aatggcgcat tgctgcagta acagtaaatt gttcaatccc aaagttgttt
     6061 ggaatagttt tagtcgtcaa atagccgatt tcttctatag ttccacgatc aatctcattc
     6121 caaaaatgtt catcatagtt gctgtcttcg ttttgaacat ttccatccaa ttttgatacg
     6181 agtttgactg ttccgctacc ttcaagcatt tctatagtta aatagatata agctgattct
     6241 tttttgacaa tgctcagaaa acgttcgaag gaaatgcgta ctttattagt agaagtagtg
     6301 attgtgaatg tacgagataa tacaccattt ttcatatcta attcccagta aaagtcttct
     6361 ggttccaaag aagccaagtc gatcagctga tcgttgatcg aaatatctat cgcgataaag
     6421 ttcaaggcgt tgatcacttt tccaaagtat tctggataac catttttcca ccagccgaca
     6481 cgtgtcttat cgggatacca gacacccgcc aaataagtac cttgatggtg gtcccctgag
     6541 taagtttctt caaagttccc gcgcatcccc atataaccgt ttccaatact tgttaaagat
     6601 tcttgcagtc gaagattttt tttatctaat tgtgtcgtgc tgattttcca tggatcaata
     6661 gcaaatagtc gtttgatctg tttcattttt ctcctcctaa tgagctgttt tatacgttca
     6721 taataaacgc aaccgattgc acaagtcaat agacaaaaga aaatatttca tagaaaaaag
     6781 cttaaaaaaa taaattttta ggagaaaatt atagaaggga acacacgtat tataggtttt
     6841 atagaatggt atagacagaa aaataaaaaa taaagcattt acaaaaaaga aaacgcacgc
     6901 tataatacgt ttaacgaaac cgattgcgta aaggagctaa acggaatgaa aaagatattt
     6961 agttttgagt tttggcaaaa atttggaaag gctttaatgg ttgtggtagc agttatgccg
     7021 gcagctgggt tgatgatcag tatagggaaa tcaattccct tgatcaatcc tgattggacg
     7081 ccgcttgtca caacgggcgg agtaattgaa aatattggtt gggcaattat tggtaatctt
     7141 catattttat ttgctttagc aataggagga agttgggcaa aagaaagagc aggcggagca
     7201 tttgcagctg ggatctcatt tattttaatc aatcggatca ctggggctat ctttggtgtc
     7261 acaagtgaca tgcttgcgaa tgaagatgca tttacccaca ctctgttcgg tacgaagatc
     7321 atggttaaag gattttttac aagtgtattg gaagcaccag ctttgaatat gggagtattc
     7381 gtagggatca tcgctggatt tgtcggggca atggcttata ataagtacta taattataga
     7441 aaattgccgg atgctttgtc atttttcaat ggaaagcgct ttgttccgtt tgttgttatc
     7501 ttatggtcaa caatcgtggc attgattctt gctgtggtgt ggccaaacgt acaggctgga
     7561 atcaataatt ttggtttatg gattgcagaa tcacaagaaa gcgcaccgat tctagcaccg
     7621 tttttatttg gaacattaga acgtttacta ttgccatttg gattgcatca tatgctgacg
     7681 attcctatca actatacaca gcttggcgga tcgtatgaga ttttatcagg cgcacaggcg
     7741 gggacacaag tatttgggca agatccgtta tggttggctt gggccactga tttagtgaat
     7801 cttaaaggtg caggggatat gtcgcaatat gagtttgtgt tgcataactg gacgccggct
     7861 cgtttcaaag taggacaaat gattggttct tcaggtatct tgatgggaat ggcttttgcg
     7921 atgtatcgta atgtcgatcc tgataagaaa gcaagatata aatcaatgta tttttcagca
     7981 gcgttggctg tctttctaac aggtgtaaca gaaccattgg agttcatgtt tatgtttgct
     8041 gctgtgccat tatatgtcat ttattcagtg atccaagggg ctgcatttgc gatggcagat
     8101 atcttgccat tgcgggtcca ttcatttggg aatatcgaat tgctgactcg gacaccgtta
     8161 gctatcaaag cgggtctagg tggagatctt atcaacttcg tgttgtgtgt gatcgctttt
     8221 ggtgttgtta cgtatttctt agcaaatttc ttgatcaaaa aattcaactt tgctacaccg
     8281 ggacgtaacg gaaattacga caatgacagt gaagaaaccg ttgtatctaa cagcggaaca
     8341 ggaacagcag atcagcaagt ggtccagatc attcatttgc tgggaggaaa agaaaatatc
     8401 aaagatgtcg atgcttgtat gactcggtta cgcgtaagtg taaatgatcg agaaaaagta
     8461 gggactgaag aagcctggaa acgagcaggg gcgatgggat tgatcgtcaa agacaatgga
     8521 gtccaagcag tttatggacc aaaagcagat gtcttgaaat cagatatcga agatctgctg
     8581 caatcaggag cagagattcc agagccagaa atggtttcta caggaaatgg acaagcaggt
     8641 agtaagcaat acttaggtat agaacaagaa ctagtttccg cagcttctgg agaagtgatt
     8701 cctttatctg aagtaaaaga tccggtattc tcacaaaaaa tgatgggtga cggctttgct
     8761 gttattccaa catcaagaga agttgttgcg ccgatcgctg gaaaagtgac aagtattttc
     8821 cctagcaaac atgcaattgg gctggaaacg aaagatggta tcgaagtttt gatccatatg
     8881 ggaatcgata cagtccaaat gaatcagcca gcttttgaga ttgctgtcaa agaaggccaa
     8941 gaagtaggaa caggaacgaa attagctgag atggatcttg atgtgatcca aaacgaagaa
     9001 aaagatccaa cgatcatgat cgtatttaca aacgataaag tagaagaagt agtgatcaag
     9061 caattaggta cagtgacagc tggtaaagtg atcggctcca ttaaaatgta aggagaggtt
     9121 gtgaaaaagc tgtcctgcat caagtcataa gaacagccaa acaaaaatag ctcctcctat
     9181 ttttcgtttg gttgggctta ttaccgagaa gcagcagttt gaatactgtt tagtggagag
     9241 gtcgtgaaaa agctgccctg caccaagtga taaaaacagc caaacaaaaa atagctcctg
     9301 gtccattgag cttattactg aggagttagc aggagaacac tatttgctgg agaggttgtg
     9361 acaaaaattt tgtcacaacc cttttgtttc gaaatgaaga caaggagaaa accaatgaaa
     9421 ttcatgacac tcaacacgca tagctggctt gagccagaac cagagaaaaa attgcaagaa
     9481 ttagcagata agatcctgtt agaagattat gaagtgattg ctttacaaga aatcaaccaa
     9541 ttactggaat ctgaagaagt agaacctgcg aagctaatga agttctgtcc ggtaaagaat
     9601 caagtaccta tccgtaaaga taattttgcc taccgtttag ttcagctttt aaaggaacac
     9661 ggaaaagagt atttttggag ttgggaaatg agccacatcg gttatgataa atatgaagaa
     9721 ggaaatgcac tgcttacgaa aaaaacattg gaaagtcagg tccttaccgt ctcccaattt
     9781 caaaagaaag aagattatca gacacgcaag atcttgattg ggaaaacaaa gatagatgat
     9841 caggacattt ttgtctcgag ctgccacttt tcttggtgga cagataaaaa aagtggcttt
     9901 tattttgagt ggaaaaactt ggaaaactac tttttggaaa ctcgcgtacc actttttttc
     9961 ctaggtgatt tcaataatcc agtagactct caaggttatt atactgtaag agaaagttgc
    10021 cttcttcttc aagattcgta tgttgtcgcg aatgaaaaag gaaaagcagc tactgtggaa
    10081 aagaaaatag atggttggga acaaaataca gaaaaattgc gtatagattt tattttcgtc
    10141 cctgaaggaa tgcaggttaa aaaatatcaa cggatttttg atgggatcga tagtccaatc
    10201 atcagtgatc actacggggt ggaaatcgaa ttagatgtga acgaataaaa aatataacat
    10261 ataacataaa aaaactgatt aaaataaaac tctccaaacg attataccgt ttggagagtt
    10321 ttttgatcgg atgtatttat cccttttgcc taagcacgta aaagcttgta tctatgataa
    10381 ataaataaac atagcaaggt aaaccagcca atcaaagtaa gagaaagaat gaaatagaaa
    10441 tagattggcg tttgataatg aagcgtgagc tcgttgattc ctttttgctg cttcacgatt
    10501 ggggtcccga tatctgttac ttcataatca gtcaatgttt ttccattttg ctgtagcaca
    10561 gtccgatcgt agacgataac agggatatga acagttttgt ccccagtgtt tttccacttg
    10621 attgtcaaaa gaccgcctgg atgtgttttt ataaaagttg tttcgttttc tagtatttct
    10681 tcgttatacc ggtcgtattt attgtctttt gtctccttat agattggcag atagtcaggt
    10741 gtggtttttt ggaaaacgaa caagctggta gacatatctt tgctgaagaa tgttttcctt
    10801 gcttcttccg gcgtatcgaa tagataagta tgtcgactga caaatgtttc attttcccac
    10861 ttttccagat gctggtataa gttctggatc gtctgtgctg aaaaaataag aatgccaaat
    10921 atacttaaaa gacggaacca cttttgttca gaccactggt tcagtgaaag ggcaaggtaa
    10981 agtagaagca atagcgtaaa tggcacgaaa aatcgaaatg gaaactggat caaactaata
    11041 aaaggcacat ttttttcgat caatgtcgtc catggaatca agctagtaga aagaaaaaag
    11101 aaaacaagac ttgtgtacaa cacgattttt tggaataagg tgttcttttg ttgaaagaaa
    11161 ataaaaagca aaaaacctga taatatcaat ataggaaagg ccttagggta atggagccaa
    11221 taactgccat ccagatctat cgccttttga ctcatttctc tgttaacaaa gggaggaaga
    11281 atcttattcc cactgtaaac aatagctaat cctgcccaaa tatttgctgt cagaacaaaa
    11341 taaagcaaga ccgacttaat cagttgaagc agtgcttttc ctttttcagt ctggttaaaa
    11401 aagtaataaa gataaaaagg gatatacatc aaagctaaca tgatcgaaga cagtaaatgg
    11461 atctgtgtca taagtcccac tgagacagcg actttgataa cagggaactt tttatgaagg
    11521 acgaaatcag caatagggat catacataaa ggataaaaac aagtccccca gctagtgaat
    11581 ccttggttga tagaccagta ttgaatagaa tacgtactca tgaataaaac ggctactggt
    11641 acacttaccc aatttcgaac attgacatat ctcagtaaaa tcagcataga aaatcctgaa
    11701 ataagataaa gaatgaaatt tgaaagaatc tgataatgaa accagctacc tgcaagcaac
    11761 acgatcaatc cttgtaaata agcgaaaaat gggccgtaaa cggcattcac gatcctgcca
    11821 ctttgctgga atccataaag ggaaggaaaa taatggaaat ccccatattt aatttgttgc
    11881 gcggcatcat agaaccgatt gtaatggaat ggggcatcag cacccaaaat tagtttatgt
    11941 gtgaataaat gaggcatgag aaatgccaaa gcaatgaaaa aaattgctaa aaatgggcca
    12001 tattttttca attgtcgaac tcctttgcaa actttagata aattcatcat atatcctatg
    12061 cgagaggtag gcaagaaatt agaaaattca tgaaaatatt tatgaatttt acaagaaaaa
    12121 cataagtgaa agttctaagg agagaggatg cgacataagt tttgttgcat ctccttgttt
    12181 tgaaacagaa tttttcttaa tactcgaaac aaagtagctt tttcatgacc tctcggtaaa
    12241 cggtgttcaa tcagctgctt ctcggtaata agctcactag cctagaaaat atgagaagct
    12301 attttctgac tagcgctctt attactcaaa gcataacgca gttttcacaa cctcttcctt
    12361 aaacggtgtt caaaagcttg catctgcggt aataagccca acccaacaaa aaatatgagt
    12421 agctattttt ttgggctgta cttattactt gatgcaggac agctttttca caacctcatc
    12481 ggctttcatt ttctattttt ttcctgaacc catataataa aagaaagaac aaaaaaactt
    12541 gcaagggagg acacatgtga agcagagtaa gcaaaaacag tctcgtcgac ttttgtttcg
    12601 tttgttttta ttaatatgta tcgtcgtagg gttactgatc gctttatatc cattttatgt
    12661 ggattcttta aatagtttta ttgatcaaaa acgtatcgaa caagtacaaa aacggaccgc
    12721 agctgaaatt gaagtgcagc gaaagaaaat ggaggagaaa aaccaacgat taactgacca
    12781 aggattcaat cctggtactg atcctttcaa tgaaaagaac agaaatgaaa gtacaacatc
    12841 cagccaatta gaggaatggc tgatcggaag tatcaatata cctaagatcc aattaaatat
    12901 ttcactttat gatcggctca atggtaggat ccttgaaaat ggagcaggcg tcttgcaagg
    12961 aacctctttc ccgcttggtg gaaattcgac gcattcagtg atctctgctc acagcggttt
    13021 acctaatcga cggttattta ccgaattaga tcgtttagaa aacggagaca cgtttatttt
    13081 gactgttttg ggggagaaat tggcttatca agttaaaaat atacaagtgg tactgccaga
    13141 tgacacgtct gttctaacga tttcagaagg agaagactta gttaccttgc ttacatgtac
    13201 gccgtatatg atcaacacgc atcgtttgct agtgacagga catcggattc cttataacga
    13261 atcggtaaaa aaagaagaag gaaaaggaaa tcaggaaaga accatgcggc aatggtttat
    13321 tcttgcagga acgataatag ctgtagtcat actgttagtg tttatcggac gactaatcta
    13381 tcagtataga ttaagtaaaa aagtgcttga tttttcattt attattagtg attcgtcagg
    13441 gaaaccggta aatggtagtt cattcatttt gaaacataag aaaaaaacac ttactagaaa
    13501 tggtgtgccg ttttcagtac aaagcgacca tcatgggaaa gtcaagctgg atcaattgcc
    13561 tggtggaact tatcgaatcg tttcagctga tgatcctaaa gttgctgttt cttttggtat
    13621 tagaaaagta aaacaagaga agatatactt ttttgagggg cgaaaacttg taaaagagct
    13681 tcaaaaaaat ggtttttatt ttaaaatcaa tgaataagta aggagagaaa aaatgatccg
    13741 cacaacaaca aaattgtctg ccaaagaact ggaatctgtt ctatcgattt ggctgcatgc
    13801 taacttggat tctcatgaat tcattccatc aacttattgg gagaatcaag tagaatctgt
    13861 taggaaagct ttaccagatg cagtgattta cttagcagaa atagatcaag aaattattgg
    13921 ttttgctggg gtgattgatc agtttatcgc aggaatcttt gtgaaaaggg aataccggca
    13981 acaaagaatc ggtacgcaac taatgaaaaa aataaaagaa accaataaaa cactgacttt
    14041 gacagtctat caaaaaaatc aatcagctat tcatttctat ctttcacaag gttttacaat
    14101 tcaaacacag caaaaagatg aagcagtaaa tgaggaggaa cttgtgatga aatggaatca
    14161 aaacgctgat ttttgatgaa cagaataacg aaataatgct cccagcctaa ttttttgctg
    14221 ggagcattat ttcattttga agtcactaat ttaactgtgt gaatatgcag ttgttacaat
    14281 ctttgataaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
    14341 tgaggaacta tttttccatt tgtttctcta atactcaggt caaaacgctg atttcacaac
    14401 ctcttgataa acggtgttca aacggctgct tctcggtaat aagcccacta gcctagaaaa
    14461 tatgaaaagc tattttctaa ctagcgttct tattactcaa agcataacgc tgatttcaca
    14521 acctcttgat aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa
    14581 acatgaggaa ctatttttcc gtttctttct ctaatactca ggtcagaacg ctgatttcac
    14641 aacctctctt tcacaacctt attttactcg tttataattt tcatcgaagt attttccgct
    14701 acggatatca tctggcattc catcgtatgg ttcttcgcta ataacatctt cattgtctat
    14761 acctgcatca cccatataag tgatcgtagc aaattcagga acaagtaatt ttggataagt
    14821 ttcatatttt tcacgagctg cttccatttc tgcgatatgt tcgttttgga aagtaacagt
    14881 gatttctgga tgttcttcaa cccatttagg gaaaaagatc attccgtgaa gtttcttttc
    14941 atttggcata aagtccaatg ccacgtctgt ccctgttggc tctgtccaag tgattttgaa
    15001 tacgccgtcc gtcaatttaa cgatatcagc ttcttggtct tttacccaac ggcctttgac
    15061 cattccgcca tggatacggt aatcaacagt atggtcattt ttggcatacc attcatattc
    15121 ccaaccattg tcatacgtat agataaagtg agttccaata aaatcttcca attctttaaa
    15181 ttctttcatg tttaagcatc tccttataaa ttaaaacatg taataaacta catgttttcg
    15241 attactcatt tatgatagaa tggatttaaa gatttgtcaa ggagggaaaa ctgatggcaa
    15301 gaaaaaatac acttcgatat attttgttag ggttattaag taagaagaag atgacaggat
    15361 atgaattgaa tcaatcgttc aaaaatgaaa taggagaatt ttggcaagca aaacatagtc
    15421 agatttatcc tgaacttgca aaaatggaag agcaaggaat cattcagcat caagtagaga
    15481 tcacaggtga aaaattggaa aagaaagttt atgaattaac agaagaaggg aaggaacaat
    15541 tggcagagtg gattcataca cccaccaatg aactaccggt taatcgagac gaatttgttc
    15601 tgaaattgta tttcgtcaaa gacgtgaatg atccggcatt agtagaaatt attcagcagc
    15661 agcgtgacct tcatgaagaa aaacgacttc atctattaga gcgaaaaaaa acgatctttc
    15721 ctactgaaaa agaaaaacat gaaaattacg gacactacct gattttagcg catgcgatca
    15781 atcgggaaac agaatatgca aattggctaa cagatgtatt agaagaaagt aaccgaaaaa
    15841 aataaaaaaa tatccgaaca gtgatggaga attcctttct atatgaaaga aacgcagatc
    15901 accgttcgga tattcttatg ttcaaacagg ccttttttca agtatttatg tagcatctac
    15961 ttattaaaaa gcttggtact taggagatta gtggcgttta gagttctttt aacaactgtt
    16021 cgtagtcagc tttttcatcg acaggaagga gcttgtaagt taattcgtct gtctcgttgt
    16081 catgaatgat gtacatctta gcattctctt ctttgaagtt accgatttgt aaaatcgtat
    16141 agcgttcgtc gatcaattcg atatctttga ttgcttttga aaaaacttta cggacatggt
    16201 gcattttctt ttggcggatt tctgcctttt ctgcagcttt tgacaaagta aatccgtcat
    16261 ctaaatattt tttgatcagt tctactttta tgactgtagg taaacgatat tttctaggac
    16321 aattcgcatc agcttcgatc gaacgaatga atcccttttg ttcccaatac cttaattgac
    16381 gtggagacac acctacgata tcacttaatt cactgatgcc aacaaccaat tgatcatttt
    16441 ccaacaaacg tttaagggaa gccccaacca tttttgtcac tccttttgtc ctcttgcttc
    16501 ccttaattat atccgtatta acttatgtgt caagtaggtt gacaaatagc gaatttagga
    16561 ctaaagtatt ctagtagttt cagaaaaaat tcagaaagaa ggagaaatat gagtaacaac
    16621 caacccgtag atatttacgg aaaaccatat aatcggacac ttttagttgt tgtcttatta
    16681 attggtacat tttgtaccgt tttgaatcag accttattga cgacagcttt tcctacattg
    16741 atgaaagctt tcgatatttc agcgtctgat gtgcaatggt taacgactgg tttcttgcta
    16801 gtcaacggga tcatgatccc aataacagca tggctgatca ataaattcag ttcaagaaat
    16861 ttatatcttt ctgccatgac gatctttttg atcggaacga ttacttgctt tacagcacct
    16921 aattttagta cattactaat cggtcgtttg atccaagctt gcggtgtggg agtatcgatg
    16981 ccattattgc aaaatatcat gctatctatt ttcccgccag aaaaaagagg atcagcaatg
    17041 gggatgtcag ggatcgttat tggacttgct cctgctttag gccctacatt atctggttat
    17101 atcattgata actaccattg gcgtgacttg tttggtatgg tactgccaat cgttgttctt
    17161 gtcttggttt tagcattctt cctaatgaaa agtgttattc cattgtcaaa tcctagcatt
    17221 gatattttat ccgctatttt atcaacgatt ggattcggta gtttacttta cggattttct
    17281 agtgtaggag atgacggctg gggaagcttg aaagtaattg gtttcttagt tgttggtgtg
    17341 attttcatcg ccttgttctc atggcgtcaa ttacatttgg aacatccatt cttggaactt
    17401 cgtgtattca aatcatctac attcacgatt gcagctgttt tagctggtgt aacaaatatg
    17461 gcgatggtag gggcagaaat ggtcgtacca ttgtatattc aaaatattcg tggagaatca
    17521 gcattccatt ctggcttgat gttgttgccg ggtgcattga tcatgggggc tatgatgcct
    17581 gtgacgggtg cgattttcga taaatacggc gcgaaacgtt tagccatcac agggatgttc
    17641 attttgacag cggcaactgc accatttgct ttcttgacaa aaacgactcc agttttatat
    17701 atcgtgatcc tttatgcgat ccgtatgttt gggatctcca tggtcatgat gccggtaacg
    17761 acttctggta tgaatgcatt gccaaataac ttgatcagtc atgggacagc ggtaaataat
    17821 acattccgtc aaatcgcaag ctcgattggt acagctattt tgatcagtgt gttgacgaat
    17881 gtgacaaaag caaatatccc aagcaaatct gtattggata atacgccatt agcttataaa
    17941 gatcaggcaa tcaatgccac actgtcaggt taccatgccg cgtttatcgt agcgatcatc
    18001 tttgggattc ttggctttat tattgccttt ttattgaaga aaaaagaacc tgttctaatg
    18061 aaagcggggg ataatgcatg attattggag ttttgattgt cagcttgctt gcttttgctt
    18121 taacgaacgt gttcgctaaa aaaacatggc aaaccttttt atctttgatt ttcggactaa
    18181 tcttcgtcgc ttcactaagt ttgatcgtcg ctaatttgtc caatcacttt ggaatggaaa
    18241 aagtaacgga aacaaaaaca gaaaaaattg tttccagtgc tgattcccaa ggagcagata
    18301 tgcttttgta taaagcttta gggaatggaa aagaaaaagt gtatctttac cgaacaaatg
    18361 aaaaacaaga aaaaccaaaa gcaactggta cggataacga aacaaataaa gtagaaaaga
    18421 cagacggcga tgctgaaaaa gtgacgaaaa ctacttattg ggaatacaaa aacgacatgt
    18481 ataaattctg gttcaatatt gctgataaca atcacgaata tgacagccga gtgaatacat
    18541 tcaaaatccc agagacatgg gtagaattaa gtacggacca agcagccaag ttagctgaat
    18601 tagtgaagaa acagcaaagt acgatggaaa gtgaagcaaa agcttatgtt caagacggta
    18661 tggtaaaagc aatgactgaa aatccaaaaa tgagcaaagc agagcaagaa caacgtacga
    18721 aagccttagc tgctgaattc caacaacaag cattcgcaaa attagtgaaa gaagcaaaag
    18781 gcgaataata ttttgaacac catgtaggag gttgtgaaaa agctgctctg catcaagcag
    18841 taagaacaat cagataaaaa tagcactcca tatttttcat ctgattgggc ttagtgccgt
    18901 agatgcaagc ttttgaacac cgtttaagga agaggttgtg agcctgccgt ttaactctga
    18961 gtcacaagga gcaatttcaa aaaacagctt ctcatgtttg ttgactattg tgacttgtga
    19021 ccgaggagtt ggcaggagaa caccgtttat tcgaaaaaag gaactgcgac aagacttttg
    19081 tcacagttcc ttcttttttt tgctatgcta tactagatgt aaaaaatagg agaaataaaa
    19141 tgagggaaat ttattctttt gaatcaaaaa tctatgcttc cgaagtcggc aagggcgggg
    19201 catatattat ttttccgtat gatataagaa aagaattcgg tgctggaaga gttaaagtcc
    19261 aagcaacttt tgacaatgtg ccgtatgaag gcagtatcgt gaatatgggc gtgaaaaatc
    19321 cagatggttc agtctgctac atccttggac tacgaaaaga tattcgtaaa aacatcggaa
    19381 aagaaatcgg tgatattgta gcagttacag tgaagcaaaa ataaaagagg ttgtgacaaa
    19441 agacgtgtca caacctcttg ataaacggtg ttcaaaagcc agtttctcgg tagtaagtca
    19501 aatttatgca aaaatgtgga aacccatgtt tacaaaattt ttcttactac tcgaaacgaa
    19561 gcggctttat cacaacctct tgataaacgg cgttcaatca gctgtccctc ggtattagct
    19621 caaaaacggc aaaatatgag aagctatttt tccatttttt tctctcatac tcaggtcata
    19681 acgctgattt cacaacctct tctttcataa tggtttttca ccatctttat aataaactgg
    19741 ttatttgata tggaaatcta ttttttccaa ccaatctaaa atcttgtaac ctaactcttc
    19801 tgacatcgga aaagaggcgt tgatttgtgc attggagata tggtcaacat ggataccgga
    19861 agtgatcgta caacttcccg gaacggcagt tttgatgatc acagctattt tttcggctaa
    19921 gacatcgtct ttatggaacc gaccatcgtg gctagggaaa cgtacagttt gcatctctgt
    19981 atcacgagaa aatgtagtga ctgttccgat atgtggtgta tctccgcctg ttaaagtgat
    20041 caataagtct ttaccgatta ctttaacagc agcttggatc gtgaaaccta gtttggttac
    20101 ttcaactatc gtttcttttt ccatattaat caccctgcca acgttttgaa tgctcattta
    20161 caatttcaaa ttgatccaaa agtttcattg tatggtgatt aacaagatct tggatcgttt
    20221 gaggctgatt ataaaaagca ggaattggtg gtatgatttg cacacctagt cgtgctaatt
    20281 tagtcaagtt ttccaagtga atggcattta atggcgtttc acgaggaaca atgactaact
    20341 ttcgttgctc cttcattgtt acatcagcag cacgtgcaat caggttgtcg cctaaaccaa
    20401 cagagatacc tgcgactgtt ttcatacttg ccggtacgat gatcattcca tcggtcaaaa
    20461 atgatccgct ggcgacagca gcacctaaat ctttgtttga ataatggtaa tcaaacaggc
    20521 tttcgaattc agttagtgat aagtcggatt ccagctttaa gttctgtttt gcccatggac
    20581 tgatgattcc gtgtgtttct atcatcggat attcttttag tttcttcact aggttgatgg
    20641 cataaatggt gcctgaagcg ccacttacac caatcacgat ttttttcttc cgttgtgcca
    20701 attgttccat tttccgcact cctttttatg atgtcaaaac agttgcagat cattcattat
    20761 ttcaaatatt tttcccaatc ttctacttct tggaattttg cacgtacaaa atgttctttc
    20821 atatcgaaag gaactgtacc gtcaaagata gtttttgcac ttatcccacg gaaacgaata
    20881 gagccaggat tatattctgg taattctgat gggtccaatg gatggttcct cattcctggg
    20941 atcacgatga tatctttatc tccttggaaa cgagtgttga aagtccaaac tacatcgttc
    21001 atgtcgaaaa tatcaacatc ttcatcgact aaaatgactg tcttcaattc tttgaaggct
    21061 gataaagcaa gaatagctgc ttgacgctga ataccttcat ccgcttcgtt ttctttacgg
    21121 atttgcatga tggtcatcaa tttaccacca cctgcaggag gattgtagac atttactact
    21181 tttcctggaa tagctttatc gaccaaggca agaatacttg cttctgtagg aataccggcc
    21241 atagatacgt gttcttcact gggaccaatc gttgtttgca tgattggatt gtcttttcgg
    21301 tgagtaactg ctttgacttt cactacttgt acagctggat tagcatcccc agtatagcca
    21361 ggaaattctg gcattgcttt tcctgagttc gtgttgatat cttcttgcat tgtttcattt
    21421 ggcatgattt ctgcttcaat gatgaattca gcacgagcaa tacccacttc atcgactgct
    21481 ataccatcaa cgatttgaat aggttcgtta cgcaaagctc ctgcacacca tagttcattg
    21541 tagccaagtg gagtggtagg tggttcgaaa gtcgtgccaa tggcaattgc tggatctaaa
    21601 ccaatattga tagtgatagg cattggttta ttcaaggctt cgaattgttt ttggaagtga
    21661 ccaatgtggc gtccgccagg catgatgtac ataccgatcg tatctttatc ttctagaacc
    21721 atacgatgga tcgttacatc gctcattgtt ttttctggat ctgatcctaa gactacaccc
    21781 attgtgatgt atggaccagc atcttcagga gtatttgtag gtgcaggcaa aatgttgcga
    21841 atatcgaagt ctgcatcggt agctagatga acgacttctt gtgctggagc gtctgctttg
    21901 tctactttca caggtttgat tggattttct acagcgtctt tcaagaaacg accaagtgtt
    21961 cgataatcat ggtgcaaaat ttcacctaca cgtttacgac tagccattgt tccgatgttc
    22021 acacgtgtgc cggggaaacc tttgatattg ttgaaagtca tagctggtcc ttcttgagtc
    22081 ggacgtttta ctgtaccgcc agcaccgata taacggtaaa caccagataa ttctgcttca
    22141 ggatcgattt caatatctgt ttcgtgatat tgacctggaa gtgtttttag ttcttcgatg
    22201 acttttctta aatcatacgg ttgatctgtc atgagagatt cctccttagt tgtctttacc
    22261 tatctatagt aaaaggtgaa aaagaggaaa acaattcaac ttgttcggta aagtattcta
    22321 caatggaatg gatgcgtttt tttgataata gaataaacta tgatatactt atcactaaaa
    22381 gaaagcgcat acttagtgtt ggaggaagga aagtgaaaaa aatggaggag tcatttccta
    22441 aagcagtaaa agtggaaaat atagcgaata ttttgaaagt tacatttgaa aacggagaag
    22501 taaaatacgt gaaatctcat tggacagaag agataaccga tgccttgcaa tttggaaaaa
    22561 aaggaagagg aaaaagaaaa aatcttctcg cactttctcg taatatgtgg attgggactg
    22621 aagtaacgat tgaagcagat ggaacagtat tcataaatgg aaaagacagg tatacgccag
    22681 aagagttgtg gtacaaagga aagaaaagta taccagaatt ataaaaaata attaaaaaaa
    22741 acagcgcgaa acaaggaaca tattacttcc tcgtttcttg ctgttttcta ctatttcagc
    22801 gctcttatga ctcaaatcta aatgtggttg tcacaacctt attctgcacg caaagcgata
    22861 gcggcgtctt ttttcgctgc cattcgtgca ggaagatgac cgccaagcat cgtcaatata
    22921 gtagagacga tcactagaat aatcgcatgg acaggattta gttgagcaac attttttaga
    22981 tccgtcatgt tgtataagat gctattgata gggaacgtag ctagccatgc aataaacaca
    23041 cctaatatcc cagaagaaat acctaaaata cacgtttctg cgtcaaatac gcgagtgatg
    23101 tcttttttac gtgcacctaa agcttttagt acaccgattt cttttgtccg ttcaatcaca
    23161 gatgtataag taatgatact gatcatgatc atacttgtta ctaaagagat ccctgcaaaa
    23221 gcaataagga cataagtgat agcatccatc aatccgccag tcagttcagt catcgttcca
    23281 gctaaatcag tataaatgat tttatcttca tctgatttgc ctttattgta atcatctaga
    23341 taatccaaga tcttttcttt gtcttcaaaa ttgttcggat aaatcatgat acttgaaggc
    23401 aagctgtctc cacctaaata actaagcaat gtttgtttgg cattttcgtc aactttttca
    23461 gtagttaaga catttacacc actgtctctt tgagctttga cgatttctga ttctttgttt
    23521 tcgttgacga tttgagtcgt taattgatcg ctataagcga ttcctggaga taagagattc
    23581 attgtagaag aagatttcac gcgtaggatc cccgagatct tcaattcatc agaagcattc
    23641 tgatacatcg catcataatc tgtattaggg ataaaattcc cagttggaag ttttgtatag
    23701 taagtattgt tgtttactaa tttgaatgtt gtaccaacga tatcatcaaa atcaagtttt
    23761 tcgtcttctt tcacatcaaa tccaagattc ttcaatgcgt tgatattagt attattattg
    23821 ccgtctacga tcagcacgac atctgttgct gaggctggat aacttccggc aagtaaagaa
    23881 taattgtctt ttaaaaagtt ttctttgcta gtgtcaagct gtgtagggaa acttgacact
    23941 cccacacctg tcattgctga catcgtacta gataaagaaa gagattccgt atcaggattt
    24001 tgattcgaga agctgacagg ctgtactttg ccatttacat cacgtaaaag attgattcct
    24061 gtagtacggg taaatccgat attattactt aagttaggat cgatgtctgt tacgtaatcg
    24121 acgtatgttt gatcaatctt attcgtgtgc tgtgctttat cttcttcgct gacttttgca
    24181 gtaatcgttt tgctgtctgg ataatccgct ttgcttgcac ccaatccggc atcgtcacga
    24241 gtctggttag tcgttacctt agaaatagta atcggaaatt tcgccatcgt ttcagcttgc
    24301 gtgttatcga tttgtttttg gaatccagaa gaaagggaca gaacgatcgc gattccgatg
    24361 atcccaatac tggaagcaaa ggaggtcaag aaagtacgtc ctttttttgt tcggatattg
    24421 ttgaaggaaa gctttaacgc tgtccaaaaa ctcatctttg ttctgcgtaa gttaaattga
    24481 tcatcttttg gtcgttcgat gtgaggatgg gaatctgtta agatcttacc atcagaaaat
    24541 tcaatgattc gatctgcgta ttgatgggcc agttcaggat tatgtgtgac catgatcact
    24601 aatttttctt tcgataactc ttggatcaat tccatgatct ggatacttgt ttctgtatct
    24661 aacgctccgg ttggttcatc gcacaaaagg atatctgggt cattggctag tgctcgagcg
    24721 atggccactc gctgcatttg tccaccagat aactgatttg gctttttatg catatgattt
    24781 gtcaagccga ctcggtgcaa tgcatcttct gcccgttttc gtttttcgtc tttagaaaca
    24841 ccacttaatg tcatcccaag ttcaacgttt tcaataatgc ctagatgacc aatcaagttg
    24901 taactttgaa aaatgaaacc gatagagttg tttcggtagg catcccagtc actgtcctta
    24961 aagtctttag tagactttcc gttgattacc atatcaccgg aatcataatt atctagtcca
    25021 ccaatcacat tcagcatagt cgttttacca gaaccactag gacctaaaat cgctacgaat
    25081 tctttttgtc tgaaagcgac agacacacca tccaatgctt tggtggtggt ttcgccgact
    25141 ttataatatt tttttatatc ttttaattga agcataatca cccttctccc gtattgaaat
    25201 attcggtata ctaataagta tatcagaaca atgatcgtag tatacgaaat aaatgttaac
    25261 tgaagatgaa ctacaagaaa aaatctagaa atttttcaaa aaacagaggg agatcaatga
    25321 atcgtatttt agtagtagaa gatgatccgc aattacagtt gctttaccgt tctgtgttgg
    25381 aacgagcggg cttttcagtc atcaccgcat tgaatggaga ggatgcgctg aaaaaactag
    25441 aagcgacacg tatagaatta atcattacag atatcatgat gccgaaaatg gatggctatg
    25501 acttgctaga ctcattacgt agcaccagat ttgacacacc tgttctaatg attacggcaa
    25561 aggccgattt tgaggataag aaacgcgggt tcaaattagg agcagatgat tatatgacaa
    25621 aacccatcga tgtcaatgag atgatcctac gtgtggaagc attgcttcga cgttcaaaga
    25681 tcaattacag cagtagcttg ataatcggac aaacaaaatt agagctagat gcttatacag
    25741 tgttacaaga tcagcattcg ttgattctgc ctcaaaaaga atttctgctt ctgtataaat
    25801 tactgtctta tcccaacaag atcttcactc gccaacagtt gatggatgat atttggggat
    25861 tagatacgaa tacagaagaa cgaacgatcg atgtacatat caaacgttta aggacccgtt
    25921 ttgaaaagac ggaagatttt caaatcatca cagtacgggg actaggctat aaggcggtta
    25981 tttaaagatg aaaaaaaagc tattttcaca attatggatc tattttgcta gtattgtctt
    26041 catttcgatc ttagtgacac tgctgtgttt tctcggtttt attttcttat tgtctcgaca
    26101 ttctatctcg cctgctgaat cggctggaaa accaacgtta tacccgttat tcgtctttgc
    26161 ggggttcagt atggtcgtgg gtacaggaat atcgattttt gttgggcggc gtatcctgca
    26221 tccaatcagt gcgctaggga caaatatgag tctggtagca acgggagatt tttcgattcg
    26281 aatggatgaa cagcagaaag tagcagaagt acagcaactg tataaagatt tcaacgttat
    26341 ggtccaagaa ctcaatagta tcgagacact gaggaatgac tttgtgtcca gtgtatccca
    26401 tgaattcaaa acaccactag caacaatcca aggatatgtt caattgttac aagccccaaa
    26461 tctctctgac gaagaacgcc aaatattttt atatcggatt atcgaaagta tcacgcagct
    26521 ttcacaatta acagagaaca tcttaaaatt gaacaaactg gaaaaccagc gtatccaact
    26581 ggaaaagaaa gagtatcgat tagatgaaca aatcagagaa gtaatcgttt tttttcagcc
    26641 taaatgggag aaagaacagc tagaattgga tatcgaactt gctgcagtaa attacacagg
    26701 caatgaagag tttttgtacc aagtgtggct gaatatcatg gataacgcca taaagtacaa
    26761 tcaaatcaat ggacagattc atatcaaact atttgagaca gccacagaga ttgtactgga
    26821 agtgaccgat tcaggtgtag gaatgaatga agagaccaga gatcgaatgt ttgaaaaatt
    26881 ttatcaagga gatacaagtc gtcaaatttc tgggaatggg ctaggacttt cactggttaa
    26941 aaaaattcta gaactgcatg atggacgtat tgattatagc agtatcgaag gagtaggaac
    27001 gacagcaatg atacggttaa gtaaacaata ggaaaaagaa taaaacccct aaaaattcta
    27061 ttgaaggttt ttaggggttt ttagtcgttt ttttgtgatt agggaaatgt tcttacggtt
    27121 cttttggcat aaaaatcgct gctttcttat tgaactacga gaaatgttag aggtgtcatt
    27181 gaaacaagga catgatgcaa gaaagagagc gaaagtcatg cgtcgctctc tttttttggg
    27241 tggatagatg gacagaaaat gtagggctta gttttcttct tgatttaaat actcccaaaa
    27301 tgtatctgaa gccaaagaat gctcaccgac tttacgagta aatgcaagat aactctctgt
    27361 tgttggagaa atagggagaa tcacagtatt ttcttttaat agattcttga ctgttttttc
    27421 cataacaata gcaatcccca tgtcatttgc aatcatattg atgatcaagt cgattcttgc
    27481 tcctttataa gagatttttg gttcaaatcc agcttcgcga cacagatcta gtacaggttg
    27541 atacaagttc gtagtggggc caaggagcaa aaagttctcc tttttcagtt cgcttagatc
    27601 caatttcttt ttactagcta aaggatgatt tttaggtaga actgctacaa aatcgtctgt
    27661 ttcagtaggc aaccactcaa tcgaacttgg tggggcctgg aaacttctag caaagtggat
    27721 cgtgtcacta tgttcattgg cgtcattgta agttaattcg acactttcca cttctttcaa
    27781 ctggactgta aattcaggat ggcgtttcaa aaactcggtg attttggaaa aacctttata
    27841 attgatcatt gtcggtatcg ttaagatatt taatgaaaga ttgttgtctt tcgtataggt
    27901 ttcaagcact tcttgcatag catggtattg ttctacgaca ttttttacat atgggagcaa
    27961 taagcttcca gcttcggtca attcgatttt tctatgggcg cgttcgaata atttgacgtc
    28021 taattctgtt tctaacgaaa gaatctgttt agaaatattt ccttgggtgg tgaattgtcg
    28081 atcagcagtt ttggtgaaat tcattgtttc ggctaaatca agaaaaactt cgaatttatg
    28141 gatatccatc atattcctcc tacttattcc aataaagaat actttaacac aaaaaatgaa
    28201 ttggtgtaat cttctctgtc tgttacaatc tttcttgcag cgaaagcaat aattacagaa
    28261 atttttctga tttttttcgc ttcgtagaaa aagagaggag ttttttgatg ccaactggag
    28321 ttttgatcaa tgtaggttcc gttttgtttg gcggactaat tggcggatta gtaggaaata
    28381 aattaagtga acattttaaa gcacagctga cgatggtttt tggtgtgtgt tcgatgggga
    28441 tgggaatcta ttccattgcg ccgatgaaaa atatgccggc tgttattttt gctttagtga
    28501 taggaacagc gattggtttg attgttcatt taggtaatgg gataaataag ggggctgcgc
    28561 tgatgcaagt acctatttct aaaatcttcc ctagtgaaaa gcttggtatg acccacgatg
    28621 aatttatcag cacattagtg acggtcattg ttctattttg tgcaagtggt acggggatct
    28681 atggaagttt agattctggg atgacaggag acagtacgat tttgatttct aaatctgtcc
    28741 ttgatttttt cacagcagct atttttgcgt gtaatttagg gtatgtcgtt tctgtgatag
    28801 caattcccca attcattatt ttttatattt tgttcttatt ggcaaaattt atttatccat
    28861 tgactacacc agacatgatc ttagatttta aagcttgcgg cggattcttg atggtcgcta
    28921 ccggttttag aatgatcaac gtgaaaatgt tcccagtagc tgacatgata cctgcaatga
    28981 tcgttatcat gccactgagc tggatgtgga caaattggat tatgccactg ttataataaa
    29041 aatcaaagag aagccatttt ttgctgacta aaaaggatca aatcttttag tcagtttttt
    29101 tgtatttgac aaactgattt tgaaactata ttatatgttg tataatatag attgaaataa
    29161 aatattacac ttgagaatag aaggtgacgt aatgcacatc cagattccaa ctgttcttct
    29221 tgatggtact gtgctagcag cattaagcaa ggaagatatg tatgggtatg ccttaacaaa
    29281 aatcgtacaa gaaagtctct ctgtcagtga atctacacta tatccggttt tgagaagatt
    29341 gaaaaaagaa ggatatcttg agacctatga tgaacctttt gaaggcagaa accgtcgata
    29401 ttactcgttg acaccaatgg gaagtcgtca tttagaagaa attattgatg aatggattgt
    29461 ttttcgagat tctttagacc ggttattgga ggagagcaca aatgaatgaa tatttgaatg
    29521 aagttgtgga tcatcttcaa gaaattcctg aagacgatcg ttttgatttg atccagtatt
    29581 atgaggaata ttttttagat tctggaaaaa cattagatca gatcattgat gaatatggta
    29641 caccaaagca gtttgcctta aaattaaaaa tcagttactt ttcagaagaa gaacaagcag
    29701 aaaacgagtt agtgaaaaat ccaaaaagac aaattcgcct gatttggtta atcattatcg
    29761 gtttatttgc ttctcctgtc ctcattccac tagcactggg gtttatattg gttattgggg
    29821 gactattggt tgctttacta gcgctcattt ttagtatcta tgttttatgt atcagtatct
    29881 taggtgttgg cctattcatg atcatctcag gaatcagtgt gtttggacaa tcgattctga
    29941 gtggattatt ctttatcggt gtcggtctgt tcgccacagg aagcgcagta tttatttcgc
    30001 cactgttgct gaaaggaaca aaagggcttt tttatgtcat gatgaacttt gttaaatgga
    30061 tgggacgacg ttttattaca aaaagagatc tgcattcagc gggcgtttga aggaggacac
    30121 ataaattgag attgaaacat tttttgatta ccggtattgg tctgatgctt actggtggcc
    30181 tcctagcagg tgcaacttat acattaggcg ctcaaaagag tctgacttgg gataatggtc
    30241 ctcggttgat cgatatggtt actgagacaa aaaaaatcaa ggatgcaaac aaaatcgtca
    30301 tccatgcaga aaatcaaaca gtttcggtca tacgcggatt ggattttgag ataaaaacga
    30361 cttatgataa gacagaaaag ccagaaataa aggagaaaaa tggcgtgttg actgtgaatg
    30421 cagtcaaaaa atcaacaggt gcaatcatta gtttagaaga cacaagtgca caaatcacta
    30481 ttgttgtccc tgcagatcat gaattatctg aattgacaat cgaagggaat aatagtgcaa
    30541 ttgatatcaa cgaagtatca atcaaaaaag tgaatactaa gacacatgat ggctgggtat
    30601 cgttcaatga atttacagga ggaacaataa ctgcgaaaga tgaattaggc tcacttcgat
    30661 tagatgaggc caatgtggat aacttgatcg tcacaggtga aaacagcaac ttccatctag
    30721 aagacagttt gatcagcaaa gaaggaaaag tcatcctaaa cggtggcaat ttatctttgc
    30781 atgagatgga aaacagtggc tatactatcc aaacgtctgg tgaatcttat attgaaaaag
    30841 actaccagcc aataacaaat actttgttag aacaaggaca gaaaaagcta aagatcactg
    30901 ctaaagacac atcgatcaat attacgacgg atcaagagga caatgaaaca gattgatcct
    30961 gtactcaact ggatatttta agaaaaaaca gcaaagatcc ttccaatctt tgctgttttt
    31021 catcgcttaa cgcacataac tatagtaaaa taagaaagaa aatatctaaa aagaaaacag
    31081 ggtgaaagag tatatgaagg tagaagaagg tcaaagagaa aagttaaaaa cagaaatgga
    31141 aagattacat acttatatca ctcaactaag ccaaaccttc tatgatccag acaaagaaaa
    31201 agtgatggtt aattacccga acaattcaga aggtcgccaa ttagagcaag tgtaccatga
    31261 agttttcaaa catttattga cggtgaagaa agagctggat tattattctt taccgattat
    31321 cgatacagga atattgaagt atgatgggaa gaaggaacga tttatcttta aatctgttcg
    31381 ggaagatttg cctctttcag cagggatgga tctagaggtc ttggtagaag actattttac
    31441 agaagaaaag cactgggttc gaacaaaatt ggattattta ccgcaggcag ccggagggac
    31501 acaggcaagc ggttggtaca tcactgaaga caaagagtta gaactagaag gtgtaatggc
    31561 gcgtattcga aaaaaaaatt aaaaaagtaa cattagatat ttattgaagg ataaaggagc
    31621 gcaggaagta gcatgagaga aaaaagagca ttttatatca atggttatgc agggattgtc
    31681 ggattggtcg tattagcttt agttggattg tttttcttct atttaggtat gtggcaagcg
    31741 aaagtttggg cacttttttt aagtattttt ctttggttga tcacgttatt gttgttaagt
    31801 tcggcaactg tagtcagtcc taatcaagca aaagtaattt tgttttttgg acaatattta
    31861 ggtacgattc gagaaaatgg ctttttcctt acgatacctt tggcacaaaa aatgactgtt
    31921 tcgttgaaag ttcggaattt caatagttct gttttaaaag tcaatgattt ggatggaaac
    31981 cccatcgaaa tctcagcagt agtagtcttt aaagtcgttg atacagcaaa ggcattattc
    32041 gatgtagcgt attatcaaga ttttgtagaa atccaaagtg agacagccat tcggcatatc
    32101 gctagccaat acccgtatga tacattcaat gagaatgatt tgacgcttcg aggaaacacg
    32161 acggcagtgt ctgacgagtt gcaaaaagag ctgcaagagc gtttagcagt agcaggtgtc
    32221 gaagtaatcg aaacacgctt gaaccattta gcctatgcaa cagaaatcgc tagtgccatg
    32281 ctccaacgtc aacaagcaaa agccattttg tctgctcgac aaaccattgt tgaaggagct
    32341 gtcacaatca ctcaaatggc cttagagcaa atcgaagatg gacaagaaat caatttcacc
    32401 gatgatcgga aagtccaatt gatcaataat ttacttgtct caatcattac agacaaagga
    32461 acgcaacctg ttatcaatac aggcgacatg aaagaccgta agtgacatac tttttgtaag
    32521 ataggaagaa ggagtttagg acggattatt gtcttgaact ctttttttag ttgttttaaa
    32581 gaaaatgaca aaattgaaag aagaatgata gttgattcga aggcagaatt gttcgctttt
    32641 ttctataatc agtatataaa gtaagagaga aggggaaaaa gtgaaaaaac ttctgatcgg
    32701 tctacttgtt ttcatcgttg tggtacttgc aggggtgaaa atcgcagatt acgtagttat
    32761 gggtggagaa gaatactatg tacaaattac gacagatggt acaaaaacag tttcaaaatc
    32821 agactctgga caagaaacag tcaactatag atatatcctg cctggctata cgaaagaggg
    32881 taaggaaaaa gaactggact tcaagggaca attgactcga ccgcttcgta aaggagcata
    32941 tttaaaaatc acctggaaca aaaataaagg tgtcacttcg tatgaagaag tcgaaaaaaa
    33001 agacgtgccg aaaacagcac tggaaaaact aattaaaggg tagggaaaga aatgaacaaa
    33061 atagtcgaag tacagaatgt aacaaaagta tacggaaaaa acaatgagaa aaagacgcaa
    33121 gcattaagcg gcatcagctt cgatgtagaa aaaggcgaat ttattgggat catgggcgct
    33181 tctggttctg gtaagtcgac acttttgaat attttatcca cattagataa accaacagat
    33241 gggcatatcc gaatcaatca aaaagatgtg accacattaa aaggaaatca actagcagat
    33301 tttcgtgcga atgagattgg ctttattttc caagatttca atttattaga aagcttgaca
    33361 gcacaagaaa atatcgctgt tcctctttct ttacaaggcg tcagaccaaa agaaatcaag
    33421 caacgtgtcc aaaaaattgc agaacgttta tccatctctc atattttgga aagctatcct
    33481 tctgagattt ccggtggaca aaaacaacgg gtcgccgccg cacgtgcatt gatcacacaa
    33541 ccaacgattc tattagggga tgagcctaca ggtgcgctgg attccaaaag tgcccgggat
    33601 cttttagata cgatggacga attgaataca aaagatcatg tatcgattct tcttgtgacg
    33661 catgatccgt tttctgcaag ttattgccaa cgtattttat tcatcaagga tggcggtatc
    33721 catcaagaag tgaaacgtgg agatcaaagc cgtgattcct tctatcgaga aatactatct
    33781 attcttggaa acttggaaca gtagggggag attgactatg ctttggaaat tatcacttac
    33841 tgggatcaag agccgtttaa gagactactt ggtgttattc tcaggattag ttatggcatc
    33901 tgctattttt tacatgtttg aatcaatggc aagcaacgaa gcttttttga aaagtaatac
    33961 gatcgttgcg gctacagtta tcattttccg attcggttct gttttactag ggatcatcac
    34021 attcgtttat attttatatg caaattcctt tttgatgacg atgcggcaaa aagactatgc
    34081 aatgtttatg atgctgggag caaaaggcag aaaaatcgca cagatgattt tttctgaaac
    34141 attcttagta gggatcgcag ctactttagt gggttcagct gtcggtgtag gattgacaag
    34201 tatcgtccac cgattattag tggatcagtt agatctcaat atttcgcatt ttacaccttt
    34261 tagtattcac gggttgttga tcactgtttt gttttttgct gttttgtttt tattagctgc
    34321 tgttgtcaat gctttttcga ttgtcaaaaa accgatttta gcattgattc gtgcggatca
    34381 gacaccaaca agaatcaagc agcataaatt cttgtttttc cttgaagtag tactgggaat
    34441 tgcttttcta ggctgcggtt actatatgat gaaacacgtg gggacctatc aagtctttgg
    34501 tataggggta gccttagtta cgatcgtatt aggaacttat ttcattttcc attctgtgat
    34561 cattttcttt ttatcattac taaagaaatc agaacagatt tcattgaaaa aattgaacaa
    34621 tttcacattg tcacagttaa actttcgtat tcgtgaatat acacaaatgc tctcaatggt
    34681 cgctatgctg tttgccttgg cactgggcgc tttgacggta ggattaggtt ttaaaaatga
    34741 aattgcagac ttgacagaaa acaattctgg atatgatcta gtgatgaata atcctcgggc
    34801 agaagatcag caaaaaatca aagaactttc accaacactt tctgcttctt atactcaaaa
    34861 agaagatgcg ggaacgattt actataatgc aagtgaattt gcggctcaac cattgatcat
    34921 gataaaacat gaagatggaa caccgccgaa gatcacgaaa gaaaaagttc ctgctaaaaa
    34981 aatgaatgaa ctgactgtac aagaggaact tcgaagctat gaattgccgg aacagcaaga
    35041 aaaagaaatc aaggtagtca gtcaatcaga atttgatcaa ctgaacttgc cacaatccac
    35101 tttacagcta gttcaggtaa aagacttcca agcaaacctg aaaccaatcg aaacacttgt
    35161 tgctcaaaat aaaatgaaca atccatcttt gcaaaaagta gagtacagca accagaaata
    35221 tgaaatgtat gaagtgtata atggtctatt ctctggtttt gaatttatgg gattcttcct
    35281 aggtttagct ttcttgacca tgcttgctag ctgtttgatg ttcaagatct tgtcaggaag
    35341 caagagtgac attgctcgtt atgaaatgct tgaaaagata ggaacacgac gcgggttgct
    35401 taaacaatcg atccgtagag aagtaggcgt gttattctta gcaccaggaa tcttaggtgt
    35461 agtccatgtc ttattcggat tacaaatgtt tggtctattc atgcaaaatc catacaaaga
    35521 tatttgggtt ccgtttacga tattcttcgt attgtatttc atctactatg tactgacgac
    35581 atggttatat actggaatcg tattgaaaaa gagattgtga aaaagctgtc ctgcatcaag
    35641 taataagaac agccaagcaa aaatagctcc tcatattttt cgtttggttg ggcttattac
    35701 cgcagatgca agcttttgaa caccgtttgt tcggaaaaag aggttgtgac aatatttttg
    35761 tcacaacctt tttttcacgg tcttttatta gaatatagta aattttttct cgttactcac
    35821 ggaataagct gttaagaaaa cggtttccat gtatactgga atcagtgcaa atgaaagaaa
    35881 agagggtgca aggaacatgg aaatcaatga acaaaatttt ggcgaaaact atcacttgat
    35941 tacgatcacg aatcaaaatg ggacatcttt gtctgtcagt gatcttgggg cacgggttgt
    36001 tcattttcaa acaataatcg ataatgaaaa acgagagttg atcttaggtt ttgatgaagc
    36061 aaaagaatat ctagaaaaag acccttatat cggtgcttca atcggacgta tggctggacg
    36121 gattacgaat ggcacattca aattagatga tgaaacgttc gaagtaaaaa cagacccgga
    36181 cactggtcat tgtttacatg gtggtgcacc tagctttgaa gccaagcagt ggcattatac
    36241 agtcatcaat ggtgaaaacg aagcatcggt cattttctat cagactagcc cagatatgga
    36301 aaacggattt cctggaactt tagatgtaga agtacggtat acgctgacga acgatgatac
    36361 atggcgagtg acggtccaag ggatcagtga ccgcaaaaca gtattcaatc ctacaaatca
    36421 tgtctatttc aatttaaccg gtgatccagc acagtcaatc gacgaacata tactttggtt
    36481 gaatagccga ttatttgcta cgctcaataa agatacaacg cctacaggag aagtagtttc
    36541 agtaagtggc acagcatttg acttccaacg tcctaaaaaa ttaggtgagg tctttgccag
    36601 tgattttcgc caatcaatga tagtgggcgg catcgatcat ccatttttgt tgaaaaaaca
    36661 atctggttta ctaaatgctg cggaattgac aagcccagat gaaaaagtat cgatccaagt
    36721 aaaaacagat gcttcaggaa tcgtgatttt tacagcaaat tttggagaag atggaccgga
    36781 aatgcgcggg aataaattag taaatcatgg cggtatcaca tttgagactc aagaactgcc
    36841 aggagcggag cgacttgaaa gttttggaga tgtcactctg gaacctaacc aagtacgcga
    36901 gtttgtaacg gaatacaaaa taaatataaa gaaatagaat aaattaaaaa gggagtgtga
    36961 cagtgtcaca tccccttttt aatttattct atttctttaa aggcagatca agccagaatg
    37021 atttgtctaa acttaacaag gttagtacag gaacagttgc agctttaact gtacgagtag
    37081 ttgtttctgg tatctgtctt gccgtaaaat tgttccacaa atcccagatt gaagcgacac
    37141 ggaagatgga agaagcgttg ttgacgcgtt ttatcgttga aaattctaat cctgtgattg
    37201 gcacgccatc tgttgtccat ttgattggca catcgaatcg cttagacata ttgaggattt
    37261 cagcgtttgc ttcttcagtt gttgctgctt cttttttcgg ttcatcatat tttgtcaggt
    37321 cgtacgcttc gatgatcgcg ttcaattttt gtgaatattg gcgatctgta gcataacgtc
    37381 cttccaaata tttggttgct tctttgtagt cttttgtttc cgacttccaa gttggtttgt
    37441 agaaatcagg attgccagtc agtccatttt tgatcaagtc ggcatagtct tccaaacttt
    37501 ccttgtaaga aggatattta cggaattgtg cgcggatttg gtagctttgt ccggaactat
    37561 cttgttcaag tgtattgaag gtcacgctgc ttcctttata tgatcctttg ataccaaaaa
    37621 ggttatgatt tggttcgctt gataataagc tgtttccaga tccactttca aggatagctt
    37681 gagccatcat gactgatgcg tagattcctt ctttttgccc gatttcctgt gcatcatctg
    37741 caatcttttt caagaactga tcagttgttt ggttttgact gaaatggaac gagccatcta
    37801 atccatctaa aatagatgag ccgcctgtca gcgaacctga agcagcaggt aaacctgcta
    37861 agtttactcg gacagcaaaa tcaggcgtga aatctgaaat agaagttact cgaactttat
    37921 ctcctggttg aggcgcatgg ataaattgtc cgttcccaat atagatacct acatggtgag
    37981 taacaccgga agaaggtccc cagaagacga ggtcgccagg ttgggcctga cttactggaa
    38041 tctgcgtacc tgcatattgc tgttcgcctg tccagccacc gatataatga ccggttgctt
    38101 tcatatatac gtaataagtc aaaccagaac agtcaaaagt atttggacct tttgctcccc
    38161 atacatatgg ttttccaaga tgcttgaatg cttctcgaac gattgcttgt tggacattcg
    38221 ttgtatttgt aggcaataca gcatcaattg gtgattttac aacaaaatca gaagaagcag
    38281 aagatggatt ctctataccg ctttgatttg ctgtatttgg acgagatgaa gcattgttcg
    38341 ttccgccatt cgatgaacca ttgtttggat ggtttggttc tctctgagta tttccattgt
    38401 tattcgatcc agatgggttt gtttgattcg aagaattccc gctgttcgaa ttattgttat
    38461 tattgtttga attatttgaa ccattattat tgttgttatt acccacatct ggtttgtttg
    38521 gcgtttccgg atctggtgta ctagggactt cttcactagg atcagttggt ttctctgttg
    38581 aagtatccgg tccagcttta aattctgcag taatagataa attgttcgta cctactgtaa
    38641 aggtctttgc atcataattt acttctttgg caccattaac agcgactgaa gcaatttgtt
    38701 caccttcagc tggcgtaata gtgtaagtta ccttcgtttc cgctaataaa ccttctaccg
    38761 ttccactttc cgtaatatcc aaaggttgct gttcagggga atccgctgtc gaagcagtca
    38821 gttggatctt accaatcaaa gaaggagcaa ttgtaaggga atatgtctcg gctggctttt
    38881 cattttctga tggatcagcc ggatcaattt cagttggctc ggtcgatcct gttgttgagt
    38941 tagttgttcc agttgggtct tctgtaaaag aatccgttgt ttcactagta gctgagctgg
    39001 atgtagtcgt atctgttgtg actgtttgat cagctatttg attatctacg gcaaatacgg
    39061 tattggtcga caaaacagac ggagcaatca gccaagtagc agctagcaaa cgtatcgttt
    39121 ttttattttt cataataaac tagtcctttt cctttcattg attttctgtc ttattcagca
    39181 ttcattagac attttttgga acagataatc gtgtcgaaaa gctttttctt ttcataaatc
    39241 tgtctgtgta ttctaaataa aacaatttgt aaataagcaa cgagcattca ttcgtttttc
    39301 tttgacgttc attttattgc atagaccacc tttgtttggg gataaacaag tggggataaa
    39361 aatggttatg catatgtaaa ttataccaaa gtttggaaag tatcacaaaa atttataaaa
    39421 ataatgatcc taaaaagaaa aagactgaaa tatgtgataa acatctcata cttcagtctt
    39481 tttcattaac tattcataag acattaggtc ttcatcaaac ccgctaacga gagtagtgat
    39541 cattgctacg actagactaa cagccagtcc tgctaagtac cagaaaaaag taccggaaat
    39601 gaatgcaggc aatgtggtca gactaccaaa tacaaaagcg atcgctttca cttgggcaaa
    39661 tcccattaca gctccaccag cagctgcacc aatgcaagca gcaacaaatg gttttttcaa
    39721 tgggatcgca attccgtaaa cagttggttc ggtcactccc gcaagtaaaa tcgaagcaaa
    39781 agcagaaccg gagatcgaac gggtttttga acgtttactt cgcagaaata cacctaaagc
    39841 tgcaccagcc attccaaaat tggctgctcc tgtcaacgga acgattcggt cgaacccata
    39901 agcagagata ttactgatca tgacagggtt tacagcccat tggataccaa atattaccaa
    39961 aatattccaa ccaccagcga tgattgcgcc actgatcggt ccgttaatat ccatcatcca
    40021 agtaattgcg gcagctaaac cttcgccaag gtaaacaccc gcaggcccga ataccattaa
    40081 cgtcaaagga accgtgataa ctaatgaaag taaaggtaca aatactaatt gcatattttc
    40141 gcgaatatat tttttgagga atttttcaac aaaagaataa aagaaaatac ctaaaatcgc
    40201 cggcatgaca gtagacgtat actgcatcag tactacagga atccccagaa aatcagtagc
    40261 tgctttgcca ctgtctgaaa gtaaagaggt cagattcggt tcaatcagtg ctgcagcaat
    40321 gacagccgca atatatccat tcactttaaa cgttttggca gcagaaaaag caagaaagat
    40381 tggcagaaaa taaaagacgg cattcgacgc agcagacaaa atatgataag ttccgcttgt
    40441 ttcactaagc cagccaatcg tagtcgctaa aacaaccaga ccttttaata taccagaacc
    40501 ggcaaacagc ggaatgatcg gcgtaaagat ttccgatatc aaaccaaata gtttttcgat
    40561 cggatttagc ttttctttcg gagctgaatg atcgatttga cgcgtcaatt ccttgtaagc
    40621 aggagccaat ccctgatcca tgattatttc tgcatatcta tcgagtaaaa tgaaatactt
    40681 aatggaaggg atttgctgtt ttaatttttc tgcattggct actggctgtt ttttcaattt
    40741 gatacgaagc cgagtcgcac atggaaggac agaatcaata ttgtcttttc ctcccaactg
    40801 ttcaatcagc atatgaatct gctcggacag taccatctgt tcaggattca ttgtcgtttc
    40861 cattagaaga ccactccact cactaatata atattggcgt aaggtgtcat ttcgcctgta
    40921 cgaataaatg catgacagtt attcaactct tttttcattt cttcatgtgg gataaagcta
    40981 atcggtgtat ctggtaacaa taatttgatt ttttccaata tttccgggtt cattgtcttt
    41041 atttcttccg ccaattcaat cgattgtacc tcaagttctt ctaaaacgtt ttctaaaaca
    41101 gataaaaaac ttggaagacc gtttgagaca gccaaatcta ttttttcagt accaaagggg
    41161 acaggcatgc ctgcatcccc gatacttaat ttatcaaagt gccccatttg tgcgattact
    41221 cgtgaaatat ctgaattgat tacttttcct tttttcatgt ttgtttcttc ctctcattgt
    41281 taattttaga ctgctgattg ttctaaagct tcgcggtaag ggatagaagg ttgcgcacca
    41341 taagactgca cagcaacaga agaggctaga tttccataaa ggatcgcttc tttcaagtta
    41401 ctaaggtctg gctgaagtgt gctgcttaat gcgccaataa atgtatcacc tgcggctgtt
    41461 gtgtcaacgg catccacttt aaaagcaggg acgataccgt gttctttttc tgtatgatag
    41521 aaagcgccgg cactgcctag tgtaatgatt actgttccaa tacctaattc atggagtttt
    41581 tcggctgctg cgaccaaact gttatgatct gtcactctga ttcctgtaat gatttctgtt
    41641 tctgtttcat ttggtataat gatatctgtc ttttcaagta gttcagtagg aatcgtttca
    41701 cgagctggtg caggattcag gatcgttgtt tttcctgcgt cttttgcaat agaaaaagct
    41761 aggatcgtcg catctaagct actttcaaac tgagcaataa taaagtcact gtttgtaatc
    41821 agttgcttgt tttttaggac ttcttgttca tggaaagcat tatttgcccc tgcatggatc
    41881 aagatactat tttctcctgc tgcgtctacc ataatcattg cttgtccggt tgtggcgcct
    41941 tggatttcag ctatcccaga tgtatcgatg ttttcttttg tcagtagatc taataactgt
    42001 tgtccttcgc tgtcagcccc aacgcctcca ataaaagatg tccgtgcgcc tgaacgtttg
    42061 gctgccactg cttggttggc acctttacct ccgccagcgt gaaaaatctc atgcgcatgc
    42121 atcgtttcgc ctggcttggg catgttggtt aaacgaaggg tagtgtccat attaatactt
    42181 ccaattactg taaccgtgtt cattttacaa acctccaact atctcattta ttttgatggg
    42241 aaaattattt tttaaaacgt tttagtaaaa cgttttaata gttcgataaa aatatagcac
    42301 accttgaaag ctatttcaag ggtgcagttg aaaatctttt ttctaatcgt acaggtaatc
    42361 ttttttcttc ccattctttt tctgggaatt ggatccgatc taacaataac ttggcagatg
    42421 tttgtcccaa ttcgaagatt ggttgtgcga tcgttgtcag tttcggcttg atatactcgc
    42481 acatatctat attatcatag ccaataatgc tgtagtcttc agggatgctt tttccagctt
    42541 cctctaatcc gcgatataat ccaaaagcta attcatcatt taaagcaaac acaccagttg
    42601 cagcagaatc aagaagttct gctgtgatct ggtagccacc ttgttttgag aactgtgtag
    42661 gtaagaggat cagttggtcg tgagggattt ggtaaacatc aagagcagat ttaaacccct
    42721 caatccgagc gtggacattt tccggtggat tttcaggata gacaagggcg atcgtttgat
    42781 gtcctagact aagcaagtgc atgcccgcta ggtaaccacc gcgaaaatcg tctgttcgta
    42841 cggcatcact aaatccttca gattttttct gatccaaaac aatgaagggc cggccttgtt
    42901 ttttcaaatt ttcgttgatt gcatctgtag agacagcaga agtcgcgata atgaatccat
    42961 ccacacctcg acgtgtgagc tcggctagat attcgatttc tttttgatga tcagaatcag
    43021 cattacataa tatcgtgacg aaattctgct tatacaagat atcctcaatt cctcgcatca
    43081 gtgtactgaa gaatggattc gtgatatcag gaacgagtac accaattgtt ttcgtttcct
    43141 tggtaatcat ttgtctagca aaatagtcag gctgatagcc taattcttct ttggcagcta
    43201 aaactttctg aacagttttc ggactgaatt tctccgtatt tccatttaat atcaaggaga
    43261 cagttgtgat tgaaacgccg gaaagtttag cgacttcttt gattgtgatc ttttttttca
    43321 ccatgttcat actcctatct aaatcctgtg gttattttcc catgaaatca aaaagaagta
    43381 aatgaaaatc acgtgtgcca gtacttattt gctttgttgg atagcttcga ttatttgttt
    43441 cgttgagcgt actcgtgcag ttttcggaaa tatctttttt atgaacaatt gatgggattc
    43501 tttgtcacga tcactgcaag catcttcagc aagcacgata tggtacccgt gttgaaaggc
    43561 atctaatgca gtagcatata caccgtttgt tgtcgctaca ccgcttaaaa tgatagtttc
    43621 gattccacgc cggcgaagtt gaagatcaag agaagtacca aaaaaagcac ttggattgta
    43681 ttttgtgata gtcaacatat tatctgtatc tttcaaagaa tccttcaaaa gtaaatcagt
    43741 gaattctgga ggtacagaag cagtcattcc acccatatca gtttgttgac tcaaataagg
    43801 gaaagtggag atgtctacgt tcactaaaac tttcaaggca gcggtacgtt tcaatgttct
    43861 tactaacaaa tcattgtttg tcagaataga tgctgcagtg tgtggagaga gtgtaccgtt
    43921 atttacgatc tctttttgca tgtcgatcgc gacaaaagca gtttttgata aatcaaaaat
    43981 catattttcc tttaaatcat tcatgatgtt ccttctttca aataacaatg ttttttatgt
    44041 aagtaaatca taaatcgttt atttgtcaac taaattaaag gattcctttc tttagtctag
    44101 agaaattcag tggtaaaata aataagtgtg agaaaacgca ttcgatgcat agatatagcg
    44161 agaaatatcg tgaaaatgga ggaatcagag tgaagtatgt cgaagtaaaa aatgaataca
    44221 aacgatacaa aatgggagaa acgaccatta cagcaaatga cgatatttct ttttcaattg
    44281 aaaaaggcga attagtgatt atacttggtc caagtggagc aggaaagtca acgattctta
    44341 atattttagg tgggatggat acacctgatg aaggtcagat cattattgat gacacagata
    44401 ttgcgcaatt ttcagataaa cagcttactg cttaccgacg aacagatgta gggttcgttt
    44461 tccaattcta caatctcgtt cctaatctaa cagcaaaaga aaatgtggaa ttggcaacgg
    44521 aagtttctcc tgatgcgctt gatcctgtag aggtattgag gcaagtgggc ctagctcatc
    44581 gattgaataa ctttccgtcc caattatcag gaggcgaaca gcagagggtt tcaattgctc
    44641 gtgcactagc taaaaatccc aaacttcttt tatgtgatga accgacaggc gcgctggatt
    44701 ttgaaacggg caagcaagta ttgaaattat tgcaaaacgc tagcagacaa cacggcaata
    44761 ccgttttgat cattacacat aattctgctt tagcgcccat cgctgataga gtcattcaca
    44821 ttaatgatgc taaagtaagg tctgttgaat taaatgatca tccttcatcc attgatgaga
    44881 ttgtatggta gggggatttt atgaaaacaa gaacatatct taaagcaggt tttcgcgaaa
    44941 ttcggcaatc taaaggacga ttcattgcaa tcatccttat tgtcatgcta ggaacacttt
    45001 tatttgtagg tgtcaaaact gctggacctg tcatgcaaaa aacgatggat cactatgttg
    45061 gtacagcagg actttctgat ttgcaaatcg tttctactgg tggcttgaca caaaaagata
    45121 ttgctcaagc agaaaagatc ccagatgcaa aagtagaaac aggaaaacag atctattatt
    45181 ccaatactgg caaaaacgaa gtgattcaaa tattttctta taacaaaaat aacaagcaga
    45241 acaagctaca attaactgat ggaaaactcc cggaaaaacc aaaccagctt gtattggatg
    45301 aaaaagcgga agatgaaggg tataaaatcg gtgatattta tcagattgat tcagatgaat
    45361 tgaaagaaaa agagtatacc atcacgggct ttgtccgttc tccattgttc atcaacaatt
    45421 tggagagagg atacgcgaac gtcggaaatg gtagcgtcga ttattttgtc tatttacctg
    45481 aatccgtttt taaaacagat atttattctg tcttatatct tgattttaca aacgtaaaga
    45541 atttgaatac gtacagcaaa gcttacaaag ataaaatgga gcaaaatcaa gaaaaggcag
    45601 aaaagtattt acaagatcga cccgaagaac gcttagaaga gctgaaaaaa tcggccaacg
    45661 aagaattaga accggcacag caaaaaatag cggatggcaa agcacaaaca acgcaagcaa
    45721 gaacacggtt agaagatgct aaaaaacagt tagcgcaaca gtcagcaact atccagcagc
    45781 ttcctgaagc gcaacgaaca atcgctgttc aaacattatc tcaacaagaa gctcaacttg
    45841 ctgaacaaga aaggcaatta gttgagaaag aacgtgaact ggcctctgca gaggaagaat
    45901 tgaatcgaaa tgcagaaaaa attgaaaatt taactaaacc atcataccta tacaatgaac
    45961 gttcagaaaa tgtcggtttt caagaatttg gtgatctgtc tgatcgtatc gctgcgattg
    46021 ccaatgtttt tcctgttttc tttttcttta ttgccgcatt gatcaccttt acgacaatga
    46081 cacgtatggt agaagaaaac cgcagggaaa tcgggacatt aaaggcgtta ggttatacga
    46141 aagttgaaat cgcaaaaaaa tatgcaatct atgcaagtct agcctcaggg ataggtattg
    46201 ttttaggaac gatattagga acgaatcttt tgccaaggat catttttgag ctgtctaacg
    46261 agcggtatga tattgggagt gcgcttattt tttatgactg gccgccgatt ttacaagcag
    46321 ctgccgcatt cttcattgcc gcatttggcg ctgcaatgat cgttttattc aaagatttaa
    46381 gagaacggcc tgctgcattg cttcaaccga aagcaccgaa gccagggaaa cgcatttttc
    46441 ttgaatacat cactccgctg tggtcacgcc ttagctttaa tcaaaaaatc agttaccgaa
    46501 atctcttccg atataagtca agaatgctta tggcgattat cggaattgct ggatgtgccg
    46561 ggctgatggt tgcaggcgtg ggattgaaag attctctaag ttctgtttca gccaaacaat
    46621 ttggaccgat cattgactat caagcaatcg ttacattgga ttcatccacg gaagatagtc
    46681 gtcaaaaagc agcggatatg ctgcagaagc aagaaaaagt aaatgagatc ctagctattc
    46741 atactcaaac cgtagaattg agaaaaaaag gacatgcttc gcaaagtctg acagtgatcg
    46801 taccaagtaa aacagctgat ttggatcgtt ttatccattt aactgatctt gaagagaacc
    46861 cacgctcctt gcctaaaaca ggaatcgcta ttacgcaaaa agtagcagaa ctatttgact
    46921 tatctacagg agatcatatt tcgctttatg atgaagatca aaaagaatgg aaagtcgaag
    46981 taaaagaaat cgtgaaaaac tatctaggta gctttattta tatgtcccct gaatattatg
    47041 cttcagttac tgatcaatcg atgatggata atgcattttt gctgcgtaca gataagatga
    47101 caacaaaaga agaagaaatg ctttccgaga aactgcttgc cacagacgct gtgacaaata
    47161 cgtctttcat gtccaaacaa atcgaaacgc aagaagaatc aatggcgaac ttagactcgg
    47221 ttgtcttaat ctttgtcgta ttatcaggac tgctggcttt tatcgtcttg tataatctaa
    47281 ctaatatcaa tatttccgag cgtgtacgcg aattatctac aataaaagtc cttggatttt
    47341 ttgataaaga agtcacgatg tacattgttc gagaaaatat catctttact cttttaggaa
    47401 tcatcggagg atttggtgta ggatatatat tgactgactt catcttgcaa caagcgtcta
    47461 tggagaatgt catctttcca ttagtgatca catggtgggc ttatgtctta tcagcaggat
    47521 taactatcgt atttacggtt attgtgatga ttgttaccca tttcaaatta aagcatatcg
    47581 atatgattga tgcgttgaaa tcgaatgaat aaaaacagag gttgtgaaat cagcggtttg
    47641 acctgagtat tagagaaaca aacggcaaaa tagtttttca tattttgccg ttttttgagc
    47701 taataccgaa ggacagctga ttgaacacca tgaatcagag gttgtaaaaa agccgtcctg
    47761 catcgagcaa aaagaatact caaataaaat tagctcctca tgttttacat ttgagaagac
    47821 tgattgccgt agataaaagc ttttgaacac catttataga agaaacaaga atattttgct
    47881 attttaaaca agaggataga caaatacatg tctgatctct tgttttttat tgggcaacag
    47941 acctcttaga atgtataaag ataaatttta caaacgcttt cggttcagtt ataataataa
    48001 atgataactt gtatatataa gttgtggtag gtaataaatc agttgaatgg aggtaaatat
    48061 ccatgacatt taaagacaaa gtcatttacc aaatctatcc caaatcttac aaagacagta
    48121 atggtgatgg aattggagat ttaaaaggaa tcaaagaaaa actcccgtat ctgaatgatc
    48181 taggcatcga catgatttgg ctaaacccta tttatccaag ccctcaaaaa gacaacggtt
    48241 atgatatctc tgattacaca gccatcgatc ctatctttgg tacgatggag gaattcgaac
    48301 agctaatagc cgaagcaaag aaataccgga tagaaatcat gctcgatatg gtgctgaatc
    48361 acgtttcgac agaacatgaa tggttcaaaa aagcactagc aggggaccag cattatcagg
    48421 acttcttcat tttaagagaa gagccaacgg attgggtatc aaaatttggt ggaagtgctt
    48481 ggtcgccatt tggagatacg gggaaatatt atttgcactt atatgatcgg acacaagctg
    48541 acttgaactg gcggaaccaa gcagtaagag aggaactatt caaagttgtt cgtttttgga
    48601 tggaaaaagg ggtaaaagga ttccgtttcg atgttatcaa tgttatcggt aaagacgaac
    48661 aattgaaaaa taataaagaa aatgatggca aacctgaata tacggacaaa ccaatcaccc
    48721 atacgtatct aaaagaattg aaccaagcaa cgtttgggac ggattccact atcatcacag
    48781 tcggtgaaat gagctctacg acgatcgaaa attgtatctt gtatacagaa cctagtagag
    48841 aagaattatc aatggtcttt aatttccatc atttgaaagt cgattatgaa aatgggaata
    48901 aatggtctac tcctccattt gattttgcag aattaaagcg actatttcat acatggggag
    48961 aaaagatgag tgagggtaac ggctggaatg ctctattttt taataatcat gatcagccac
    49021 gtgcgctcaa tcgatttgta gctatcgatc agtatcgaaa acaaggagca gagatgctag
    49081 caaccatgat ccatttgaac cgtgggacgc cctatattta tatgggagaa gaaatcggca
    49141 tgatcgaccc agactattca tcgatttccg actatattga cgtagaaagt ttgaatgctt
    49201 ataagttact ccttgaacaa ggattcacag aaaaagaagc gtttcgtcgg atcaaagcaa
    49261 aatctcgcga taactctcga acacccatgc aatggtcaga cacagaacaa gcaggattta
    49321 ctacagggaa accttggtta aaagttggag gcaagctaga agagattaat gtagaaaaag
    49381 aactatcttc tgaagattct attttgtcct attacaagaa attgattcgg ctgagaaaaa
    49441 catatccaat cgttgcacaa ggagattatc atgcttatga agcaaatcat ccggaagttt
    49501 atggctttct tcgccaattt gaaggacagc agctgcttgt attaacaaat ttctatgata
    49561 aagatacaag gatcgccatc ccagaaggat tcacagaagc caatattctt atcgataatt
    49621 attccgatac tgttcttcat caaagtctgg agctaaaacc ataccaggca attgctttgc
    49681 tgaaaaatta aaacaaaaac acaaaacgtc gttcctacga gctattctcg taagatcgac
    49741 gttttgtgtt ttatttaaaa taatcttctt cagaaaatga agagttttca tactctcctt
    49801 tatcgccata aaatttattg tagcgttgtt tgaatttacg gaaaataaaa gtaacgagta
    49861 atttgactaa cgtatagata ggaataccaa aaataacgcc cacaattccc attagatcac
    49921 ccatgacaag taaaacgatt aagatcgtaa tcggatggat ctgtaaacga tcacccatta
    49981 ctcgaggaat caccaagtca ccgtggagaa gttgtacggc aaaccagaca atgacaaatt
    50041 tgacagccat aaaagtagag tcttggaatg caatgatcaa acctggaaag aaggcgataa
    50101 acggcccaat atatggaatg atacataaca acccagcaga aatagctaaa acactagcaa
    50161 attctaatcc gatcagtaag aaacaaaccc agtagactgc tccaaggata aatgaagcaa
    50221 tgatttgccc ctttagaaat gaacccaatt gttgattagc aatctttgtc aaatttttaa
    50281 aatctgtacg aaatgctggt gggacaatcg ctaaaactga ctgataaaat ttttgaggat
    50341 ctctcaaaag gaaaaaagcg acaattggac cagtaaataa agtaataaaa atagctgtaa
    50401 cagttgaaaa aatgttgctg atccgttgtg cgccactttc ccaataattt ccaataaatc
    50461 cagctatatc agacgtcacg tcgtcaatag aagcgaaaaa ttgattaaat gaatcggcaa
    50521 aaggtgtttt ctccaaaaat tgtcggagac tctcttgaaa atcttgaaac aaatctggca
    50581 aactactgat caatgtcttt gcctgttctt caagaaaagg aataagccat atgcttccaa
    50641 gccccaataa aaataaaata atcacataaa cgataatgac tgacaagttc ctcgaaaggt
    50701 gcttgctcaa acgtttgatg actggttcca aaagataata caagatcagt gcaaacaata
    50761 atgggggcaa gatagtagcg ataatgattc cgacaggctt gaatataaac gagatctgat
    50821 ggaaaaaata aatgatcagc gcaagtaaga taactattcc taaaacatag taagaggttt
    50881 ttcctcctaa aaagcggatc aaacgattcg ttgtatctgt ttcttttttc actctttttc
    50941 ctcctttatc tataacttca ttatagacaa aagcgggtat aaaaggaaaa tgatagaggt
    51001 tgattgcaaa aatatcgtca atcattcata taaactttct catcaattaa aataagaaaa
    51061 cgcttgacag ttcttttaac catatgataa attaaatcct gttgctaaaa cgtaactatt
    51121 acggtttgcg aaaagcgaat cggaacattc aaatgaaaga agatgagaag aggagtgtca
    51181 taaatgaaac gattgatagg tatattggcc atgctggttt tagcaggtat gttaactgct
    51241 tgcggggcaa gtgggaaagc cgaggacagt aaagaaaaat tgagcgtgat gacgaccttt
    51301 tatcccatgt atgattttac aaaagcaatc gtcggggatg aaggagaagt agagttattg
    51361 attccagcag ggactgattc ccacgattat gaaccttctg ctaaagacat ggcaaagatc
    51421 caagatacag atatctttgt ttataatgat gaaaacatgg aaacatgggt ccccgcaatc
    51481 caaaaaacat tacaagaagg caatgtccat acgataaaag cgacagaagg tatgctttta
    51541 cttccgggaa gtgaagaagg acatgatcat gaccatgaac acggggaaga aggccataca
    51601 catgagctag acccacatgt atggctagct ccaagtttag caatcaagca ggtagcaaac
    51661 atacgtgatc agctgattga agcttaccca gaaaaacagg aagtatggac aaaaaatgca
    51721 gcagcctata ccgagaaact tcaagcactc catcagcttt atcaagaaac ctttaagcaa
    51781 gcaaaacaaa gatcttttgt cacgcaacat gctgcattca actatctagc gttagaatat
    51841 ggattgaatc aagtatcgat tgctggtctt tcttctagtg aagaaccgtc tgcggcgaga
    51901 attgctgaac tgaaacactt tgttaaagaa catggaatca actatattta ttttgaagaa
    51961 aacgccaaag atagtattgc cagaacgtta gcaaacgaag caggtgtatc tttagaagta
    52021 ttgaatcctt tggaaggatt gacgaatgaa caaatagaaa atggagaaaa ctatctttct
    52081 atcatggaag caaacctcga agcgttgaaa aaaacgacag agacagaaaa cccgctagaa
    52141 gatactttga cccccaaaaa agaaaagagc gtctacaacg gttattttga agacgaggat
    52201 gtacaagatc gctctctttc agattgggca ggaacttggc aaacagtaga tacgtatgta
    52261 gaagatggga cttttgatcc tgtttttgaa tataaagaaa aattgaatca ggataagaca
    52321 gcacaagaat ataaagaata ttatacgaag ggctatcaaa cagatattgc ttcaatcaag
    52381 atcagtgaga aagagatggc atttacgttt aagaatggaa caacgaaacg ttcaaattat
    52441 cgttatgtag ggaaagaaat cttgacctac gaggcaggaa accgtggcgt aaggtatcta
    52501 ttcgaagcag aagataagga aagtggcgct tttagatata ttcaattcag tgatcacacg
    52561 attgcaccgg ctgactccga acattttcat ttatatgcag gaaatgaaag tcaagaagta
    52621 ttgctgaaag aaatggagaa ttggccaaca ttttatccag atacaatgga tggacgtgaa
    52681 attgcacagg aaatgctttt gcactgatag gcaaaaaaga accgaagggt ttggatcggc
    52741 tggtcattta gtcggtccaa actattcggt tctttttatg aaatcaattt ctttaatcca
    52801 cggatagagg ctgggatggt ctcgccgttt gccaacgtga cttctctggt ttttttatta
    52861 atcgaccgca cattttgtgt attgataaca taggatttat gacaacggat aaaattccga
    52921 tgcattttct cgatttcttt gatcttctca tagaattgta attgggcatg agtcaaatgg
    52981 acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat attggatgtc tttgatcggt
    53041 aaaaatttga tctcatcatt aaactctatt ttgaagatat ctttttggat ttgggacatt
    53101 tgaaaatctt cgaaaatttt gctcaggata tgctcgacat tttcttttaa atcataaaga
    53161 tcttctttga cgatataatc agtcggttcg atgttgcttt ttaagatttt catcgacatt
    53221 tccgtatggg aagtcacata gattattttt cctaaaggat ctaattcacg gatcaattta
    53281 ccgatcgcta caccatccat ttcactgtct tctagttcga tatctaaaaa gtaaatacca
    53341 aaagaagaag ttctgatctt ggctgcattg agaagttctt ccggatcaga ggtagaaata
    53401 tggacataac tgtctaagtt ttcaatcatg attctatttt tgatcaccgt tgataaaact
    53461 tctaattgtt ttggatcgtc ttcacaaata taaatgggaa tcatatcatt actcctttat
    53521 tttatttgta tataaatcgt ttgagaaaaa cgctggtttt caattgatgt ttcaaggaaa
    53581 agataaggat tggtctttgt caattcatcc aagataaaca agccaaggcc ttcgtttttt
    53641 ggatttgttt ttgttgagaa ccctttttgt ttcaactggt ttaacggtaa tgtatttgtt
    53701 gttgtattga tcacacgaat catcacggaa tgattcttct tgagtatggt caattcgatt
    53761 tttttcttct ttgcagcact agctccttca atcgcattgt ccaagataat accaagcata
    53821 cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg gctcaggaaa atgaagctgg
    53881 acgatcaacc ctttttcctg tgccatcatg agttttaatg acagtaaact acggatctca
    53941 ggaactttca tattatccaa catacttaga ttggccggaa aaaggttcat catctggcgt
    54001 gtaggtaata tcgtttgatc ataataagac cgtaatcctt ctaagtcgcc ttctgaaata
    54061 tagctgtgaa gagaaaaaag cagattttgg taatcatgtt tgaattctct caagtcttga
    54121 tagttttttt ctagatcttt gatataatcc tgttgcatcc tgacttgttg ctctaataac
    54181 tgatcagcta atttcttatt agagattttc caataataaa ccaagatgat caggccaaca
    54241 cacagatata gaatgaaaaa actcgtattc aaagctaaga catcaggtgt ttcaccagaa
    54301 aaacgggtat aaaaaataat gatatagtat gtaaataata tcaatgtccc gatcgtaccg
    54361 atcatacggc ggtccacagt gtgaaaccaa gtctctaacg atttttttaa acaaaaagct
    54421 aataaagcag ataaaaaagc ggataagaca atgtgaaaat actgcaatga atctcctggt
    54481 tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc ttgttaagtg atctcctaaa
    54541 agcgacgtca ataacccaaa aggaagcgcg taaaccaatt gttgacgcga agtcgaaaag
    54601 aagaaaaaag taagcatcag cattcctata gcaattagag cagtaaaaat ccctaaaatc
    54661 gaatagaccc atccaatcaa aatacaagaa atcagaatga ctcccgcaaa cagatatttg
    54721 tatcggatgt gatggtcaat caataagata caaattgtgt aaatcaaata ttgcaacgct
    54781 atggaccata aaaacataaa gtacagctcc cattgatttt taccaaatta tagcacaatt
    54841 ggcgtattat ttttttaatt tttcagggat tttgaattca gaactcatac caaagcagca
    54901 gccagataca aaaaagtcag ataagttagt taattgttta atgattgttt ttttcatgaa
    54961 agattcctcc aaaattcatc aagtagtttg taataggaag caacgtagct atttctaaaa
    55021 caatcccaag tagcaaatag gtagaaaagt aagaagctga gaaaaataac gtaatgagag
    55081 aaaaaattag aaacatgctg atcgccttct ttaataatgg gggacgtttc tcgggttcaa
    55141 tgggattgat tgctgtacct cttgatccat agcgaagcag taacaaaaag cagctgatta
    55201 acaaaaagac catcattggg aaggagatag tcaattgcag atgtttcatc accaagggaa
    55261 cgccccataa ataaagtagt gtccacagca gacaaacgaa ttcagagtcg gaatgcaatc
    55321 cataagcata tctgcggatg cagatataag aaagaaaggt gattcctgtt tccgcccatg
    55381 agcctgtcac cagagaaaag actagaacga ccgctagttt tccaagatta ttcaataaaa
    55441 cttctaagac aaattttact tggacataca ccatatcttc ttccgatttg tctccgctga
    55501 ataaggcttc taataatttg ttcacaactt tatctttcat ctcatacgta cctccaccac
    55561 aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc ataaaaagtg gttttgacat
    55621 caaaaccgtc atgatctcct aaaaaaatct tcgttttcca agaaccttac caaaaaaagt
    55681 gacagttttg atacgaaaag tactttttat gacaagtttg tgctttttcg agtgatttat
    55741 gttaaaaaat tactgacctt ataaaaggtg atggagggat tcttatggaa aatgaacaat
    55801 tgtttgaagt cggcgaaaca tatgcattta aatctgattt atttgaatca ccaataaaag
    55861 gaaaaataga aaaaatctat gaaaatagtg tgatgatacg tgtcatgaaa tgcgcagtag
    55921 aagacaatga taccgctcat aatctgcact ggcagttagt tgtacgcaaa tcaagtacaa
    55981 tagaagaata aaaacagata aaatgttgag agcataaaga ggttgtgagt ctcccgttta
    56041 gctctgagtt acaaggaata atgttaaaaa acagcttttc atgttttatg aatattgcct
    56101 tgtgaccgag gtgttggcag gagaatactg tttatttgaa aaaagggctg cgacaagact
    56161 tttgtcacag cctttatttt catgaatagg agttactttt ggctactttt agagaagtag
    56221 cttttaagga gcagataaag tcaaggcttt tatttctata aatgaagtag taaaatgaag
    56281 aacagatttt attacaggaa ggatgccgat aattgtgatc attgttgcag gaacgatcgg
    56341 tgcagggaaa agcacactaa ctgaaatgct tgcccaagat ttagaaacaa aaccttttta
    56401 tgagaacgtg gaagataatg aagtattgcc gctattttat tctaatccag aaaagtatac
    56461 ttttttatta cagattttct ttttgaacaa acgctttttg gcaatcaaag atgctttcag
    56521 ccatgatgac aacgtactag accgctccat ctacgaagat agtatgctgt ttcatttgaa
    56581 tgcagattta gggcgtgttt ctgaagtaga agtaaagcag tatgaaggtc ttttagaaac
    56641 gatgctgaag gagttagaag aaatttcgcc acaaaagaaa ccagatctac tggtttatat
    56701 tcgtgtatcc tttgaaacta tgttagcgag aatcaaaaaa agaggccggg aatatgaaca
    56761 gctagaacaa gatcctgaac tctattccta ctataaagaa ctcaatcgac gatacgaaga
    56821 gtggtatgaa cagtttgata tatgtcccaa aatagtgatc gatggggaca aatatgattt
    56881 cgtagccgat ccggcatgtg gagaacaaat cgtacaagaa atcaagatgc gggcaaagaa
    56941 aatgacagaa gaggcagatg cccagtcgat ccgctacact acaaataacc cgaaagcaaa
    57001 gggaatcttt acaactaaat aatataaaaa ctaagcaaat tgctcactcg cagatatttc
    57061 tctgtgagca gcatcttgct tagttttttt gattcattga gatcaaatag tgaaccgatt
    57121 cgtatgataa aattgccata aatgaaatgt ctgagtgagg gccatgatca aaaataaaat
    57181 ggaaacgatc aaaatcgaat gggcgccaaa cagatgatga cagaaaacaa ggacaatagc
    57241 tcctgcgata aaggcaagaa cgacacttag atagtggaaa aatcgatcaa aatctgcttt
    57301 ttctttagaa atacaataat catataagtt cgttgctacc ccttttaaat ttccagttgt
    57361 aaataaatta gtgtaggcac gcccgttgat tttatcaaaa gctacccact ggatcgatgc
    57421 agtaaaagca atcaaaatcg ttactaatgc gggatgctca tggacgggtg tcaaactaac
    57481 aaagaaaaaa atcactgctt cataatatag aacaaacaag cgccagaaat gtttttcttt
    57541 ttttctaaaa taatcaatta gatactttgt tagaagaatc cctaagaaaa agaaaagggt
    57601 agacaatact tttttaccaa cacttagcca ttctccgtca aatgcttgga tgatcgatag
    57661 aatgatattg ccagtttgag cagaggcaaa agcaccatat tggatataag tataactgtc
    57721 catggctcct ccgataaatg tcagcaaaag tcctattgta cgcccctcgt gaaaggaagt
    57781 ctgcattttt ttcatcacct tttatgaata tttttgtctt ccttatctta gcataaacga
    57841 ttgaaaaaaa aggaaaaatt ttcagaaaac taaaatcata tcgcttccca ttttcatttt
    57901 tagaaaggtc tgttagtata aagaaaaaat agacaacgaa actttaaata accaacttga
    57961 aataaacaaa ttcaaagaag aaagatggga aggaaatcaa tcagttgaat gaaaaagaaa
    58021 ttctccgatt acaaaaagaa ttgaaacgct gggagaacaa gtataaaaag cttcaacaag
    58081 tctttcggct acaagaagaa atcattgcta cctatgaagc ggcttatggc gaagcacccg
    58141 gacttattga ggaagaagta caagtaaaag aaagtgaagg aaacagctct ttctttaaaa
    58201 tgatggagaa acgttcctat aatcgcttca atcaagaaca aaaagcagct atcacatatg
    58261 atatgaagaa acatcttcga atcatagcag gagctgggag cggcaaaacg caaacaatct
    58321 gtgcaaaagc tgtttatctg atgacgcaaa aacaagtaga cgaagaacgc atactaatga
    58381 tcacttttac aaggaacgct gcaaatgaac taaaaaaacg agtagataat ttcagccaga
    58441 gaaaaaccgc tgtccatatc ggaacattcc atagtatctt ttttaggata tacaatgaaa
    58501 tttgtcgaaa atttcctgaa gtagcaatgc aaggaataca aggagacttt tcaaaggata
    58561 ctgcacaaaa agtgaatgct gttttgcaac agctgatacg taaatataat ctttatatat
    58621 ttgatcaata tggagaaaaa acgattgctt ctcggttaga ctattggcag aatatgaacc
    58681 tttcagtaga agaaatggtt cagttagtta aagaaaaata tgattccatt gataagaatg
    58741 cacgacagcc gatatcagaa cgactgtatg gattgctcac ggaactccaa gaacaaaaaa
    58801 gaagccagca attgctagag ttcaatgatg tactccaaaa tctgaaaagc gctttggaga
    58861 atgaggagat ccagcattat atcggccaaa aatatgatta tctattcatt gatgaatttc
    58921 aagatactaa tccacttcaa tgggaaatcg tgaaacggat gacaaaggaa aacaggatca
    58981 agttgattgt tgttggagat gatgatcaga gtatctatgg attcagagga tcagagccag
    59041 catacatcaa gaactttgaa aaagaatatc ctaccaaaac tcttttctta ttaactaatt
    59101 atcgttctcg ggcagctatt gtccaaggag caaatagatt gatcagctat aataaaaatg
    59161 atcggatacc aaaggcgatg attccagcac aaaaagaagc aggtgttatg gaagcctatt
    59221 tgttttctga tactaaagca gaaagtcagt ggctaatcaa acaaattcag acatttattc
    59281 aaaaaaatgg gaaatataag gaatcaatca tattataccg atcagcttca caaacgcagc
    59341 agcttgtcca atctctgctg aaaacgaata ttccttttgt actggaagca gatagtccat
    59401 atgaaggtat ctttggtatc aagtctttcc aacatttcta tcaaaaaatt gttcattggc
    59461 aaacagcact gaatctgcaa aagaaaaatc aggcctacca gcaattgctc cggcagctga
    59521 tggcagactg ctacctgaaa aaaagtgaat gcgatcaata cttttctcct aaatatcaaa
    59581 atatagccgt tgcagattat attttgtcga taagccccaa tttaaaatcg aaatctgcag
    59641 aaatccgaga gtttgaggaa gcgttgcgta aaacagacca gcatcaagaa atctattcgc
    59701 ttgttcaaag ctatcttcat ctgccacgta tagctaagga aatcgaccag agtgatcaag
    59761 aatggatacg agaagaagta aagcagcatg ctactttcag aagactccaa gccttatcgc
    59821 aagaaaccca agcgacagct aaagaattaa aaacccgctt gattgcttac agacaaggaa
    59881 aacttgatgc actatgtatc cagagcattc acaaaagtaa aggtcttagt taccgaaatg
    59941 tctttttgat tggttgtaac gaaggaagtt tgccttataa cggagcgaca gaaaagaaag
    60001 taatcgactt taatgaaata aaagcagaac cagtaacgac gatagaagaa gaacgaagac
    60061 tattttatgt tgcgatgact agagcaagaa atcgtctgta tctatgtgta cctcaaatga
    60121 aaaattcaag aaaattgaaa gtatcgagat ttatcaaaga aaccgggagt cgtgtgaaaa
    60181 aaggaaagtg atagaagaga gggtgtgaca gaagtggtca gtttcaagaa agaagaagga
    60241 atgtacgaaa attgcttctc aaatttttgt gaaatttcag cttattttcg aagaagctat
    60301 ttctggaaca cagtttattc ggaaaaggga ggtgtgacaa gaattttgtc acacctccct
    60361 tatttatttt gaaaatgaga atactattat caaaatagag aatatataga aaaattctca
    60421 ttattcaaac gtaaataatc agttattttg atttttttta tattttatta gctaataatt
    60481 ggtattttaa aagaaattac tgtagaattg gattataatt aaaaaggagt gagaaaatga
    60541 taaaagtata tacttcgcct agctgtactt cctgtagaaa agcaagagca tggttgcaag
    60601 cgaatcaact tgaatttgaa gagaagaata tttttgccga accgttaaca gaaagtgaga
    60661 tcaaaaagat cttggcagcg actgaaggag gagttcaaga tattatttcc actcggtcga
    60721 aaatttacga aaagctgggc atagatttta acgaattaac tttaaagcaa atgatcgtct
    60781 tattcaaaga atatccttca ttattgagac gacctatttt gattgatgaa aaaagaatac
    60841 taatcggatt taatgaagat gagatccggt catttgtccc tcgtgaaatt cgatgtgttg
    60901 ccagaaatct gatctattta caaaacaata acatcttaaa ttcataggga gggagccttc
    60961 gtggaagtga aagtctatgg atcagcgcac tgtgtaacaa gtctgaaggc gaaacaatgg
    61021 ttagaacacc atcaattgcc ttatcaattt gttgacttag aagaacgcga tttaagtaca
    61081 gaagaagcag aagaattatg cagttttgaa gaagtgcaag cagaacagct atttgcgact
    61141 tggtctgagg cttttcacaa cattgcgatt gacctttcct gtgtaggaaa aaaacaactg
    61201 atttttttat gcacacaaca taccaatctc ctcagacgtc ctttgattat tatcgatgaa
    61261 gttctattta ttggatacaa tgagcagttg atggaacagc ttatcttaaa taaatagact
    61321 ttaactgttt taatcaagtc actgagcatt tcatacagtt gtaacagtcg aacacttagc
    61381 atcaagcgtg ttatgtgttc tttttttgac tttatttttc tactatagag acatgctcaa
    61441 tttatgtggt caaaattcaa atctaggtgg ggatatagag ttaaaaatat attgacatgt
    61501 gtaaatttac atgatatatt catttctgtt gttttaagta gcaaagcaat aaaatagtat
    61561 tttaaaaaac atataaaata gttgttgaca tgttagaaat gacatgataa gataactgag
    61621 ttgttaaaaa agaaccactt gtgaagcttg attctatcga aaaaaacttc aaaaaagttc
    61681 ttgacaaata acaaatgata agttatgata aatgagttgc tgtaagattt cgaaaaacga
    61741 aatcaaaaaa acttttaaaa aagagttgac aattacttgt ctctctgata tgatataaaa
    61801 gttgctacgg cagccaaaaa cgaatcgggg aacactcctg atgaagtaga cctttgaaaa
    61861 ctgaacaaag taagacaaac caaatgtgta gggcgtcttg attcaattca agacaacaaa
    61921 ca
//
LOCUS       DBBGRF010000011        60217 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000011 DBBGRF010000000
VERSION     DBBGRF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 60217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.011"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(501..1055)
                     /locus_tag="ACIZD4_000777"
     CDS             complement(501..1055)
                     /locus_tag="ACIZD4_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HGC5989731.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(1181..3110)
                     /locus_tag="ACIZD4_000778"
                     /pseudo
     CDS             complement(1181..3110)
                     /locus_tag="ACIZD4_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(3416..4132)
                     /locus_tag="ACIZD4_000779"
     CDS             complement(3416..4132)
                     /locus_tag="ACIZD4_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGC5989732.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(4133..5956)
                     /gene="glpO"
                     /locus_tag="ACIZD4_000780"
     CDS             complement(4133..5956)
                     /gene="glpO"
                     /locus_tag="ACIZD4_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGC5989733.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(5970..7466)
                     /gene="glpK"
                     /locus_tag="ACIZD4_000781"
     CDS             complement(5970..7466)
                     /gene="glpK"
                     /locus_tag="ACIZD4_000781"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGC5989734.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(7602..9062)
                     /locus_tag="ACIZD4_000782"
     CDS             complement(7602..9062)
                     /locus_tag="ACIZD4_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989735.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(9052..10347)
                     /locus_tag="ACIZD4_000783"
     CDS             complement(9052..10347)
                     /locus_tag="ACIZD4_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC5989736.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(10679..11356)
                     /locus_tag="ACIZD4_000784"
     CDS             complement(10679..11356)
                     /locus_tag="ACIZD4_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HGC5989737.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(11386..12477)
                     /locus_tag="ACIZD4_000785"
     CDS             complement(11386..12477)
                     /locus_tag="ACIZD4_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HGC5989738.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(12578..13012)
                     /locus_tag="ACIZD4_000786"
     CDS             complement(12578..13012)
                     /locus_tag="ACIZD4_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGC5989739.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(13596..15053)
                     /locus_tag="ACIZD4_000787"
     CDS             complement(13596..15053)
                     /locus_tag="ACIZD4_000787"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC5989740.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(15050..16945)
                     /locus_tag="ACIZD4_000788"
     CDS             complement(15050..16945)
                     /locus_tag="ACIZD4_000788"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC5989741.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(17003..18778)
                     /locus_tag="ACIZD4_000789"
     CDS             complement(17003..18778)
                     /locus_tag="ACIZD4_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGC5989742.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(18828..20324)
                     /locus_tag="ACIZD4_000790"
     CDS             complement(18828..20324)
                     /locus_tag="ACIZD4_000790"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC5989743.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(20518..22140)
                     /locus_tag="ACIZD4_000791"
     CDS             complement(20518..22140)
                     /locus_tag="ACIZD4_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGC5989744.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(22468..23781)
                     /locus_tag="ACIZD4_000792"
     CDS             complement(22468..23781)
                     /locus_tag="ACIZD4_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGC5989745.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(24026..24250)
                     /locus_tag="ACIZD4_000793"
     CDS             complement(24026..24250)
                     /locus_tag="ACIZD4_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989746.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(24270..24692)
                     /locus_tag="ACIZD4_000794"
     CDS             complement(24270..24692)
                     /locus_tag="ACIZD4_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC5989747.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(24834..25544)
                     /locus_tag="ACIZD4_000795"
     CDS             complement(24834..25544)
                     /locus_tag="ACIZD4_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HGC5989748.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(25562..26059)
                     /locus_tag="ACIZD4_000796"
     CDS             complement(25562..26059)
                     /locus_tag="ACIZD4_000796"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5989749.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(26096..26548)
                     /locus_tag="ACIZD4_000797"
     CDS             complement(26096..26548)
                     /locus_tag="ACIZD4_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC5989750.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(26683..27288)
                     /locus_tag="ACIZD4_000798"
     CDS             complement(26683..27288)
                     /locus_tag="ACIZD4_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGC5989751.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(27738..28358)
                     /locus_tag="ACIZD4_000799"
     CDS             complement(27738..28358)
                     /locus_tag="ACIZD4_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5989752.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(28360..29229)
                     /locus_tag="ACIZD4_000800"
     CDS             complement(28360..29229)
                     /locus_tag="ACIZD4_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HGC5989753.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(29252..29659)
                     /locus_tag="ACIZD4_000801"
     CDS             complement(29252..29659)
                     /locus_tag="ACIZD4_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGC5989754.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(29678..30967)
                     /locus_tag="ACIZD4_000802"
     CDS             complement(29678..30967)
                     /locus_tag="ACIZD4_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC5989755.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(30994..31296)
                     /locus_tag="ACIZD4_000803"
     CDS             complement(30994..31296)
                     /locus_tag="ACIZD4_000803"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC5989756.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(31321..33414)
                     /locus_tag="ACIZD4_000804"
     CDS             complement(31321..33414)
                     /locus_tag="ACIZD4_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC5989757.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKVFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(33903..34667)
                     /locus_tag="ACIZD4_000805"
     CDS             complement(33903..34667)
                     /locus_tag="ACIZD4_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HGC5989758.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(34778..35647)
                     /gene="mdcB"
                     /locus_tag="ACIZD4_000806"
     CDS             complement(34778..35647)
                     /gene="mdcB"
                     /locus_tag="ACIZD4_000806"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HGC5989759.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(35672..36748)
                     /locus_tag="ACIZD4_000807"
     CDS             complement(35672..36748)
                     /locus_tag="ACIZD4_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGC5989760.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(36772..37365)
                     /locus_tag="ACIZD4_000808"
     CDS             complement(36772..37365)
                     /locus_tag="ACIZD4_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HGC5989761.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(37369..39045)
                     /gene="mdcD"
                     /locus_tag="ACIZD4_000809"
     CDS             complement(37369..39045)
                     /gene="mdcD"
                     /locus_tag="ACIZD4_000809"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HGC5989762.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(39035..39334)
                     /locus_tag="ACIZD4_000810"
     CDS             complement(39035..39334)
                     /locus_tag="ACIZD4_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HGC5989763.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(39436..41082)
                     /gene="mdcA"
                     /locus_tag="ACIZD4_000811"
     CDS             complement(39436..41082)
                     /gene="mdcA"
                     /locus_tag="ACIZD4_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HGC5989764.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(41089..42000)
                     /locus_tag="ACIZD4_000812"
     CDS             complement(41089..42000)
                     /locus_tag="ACIZD4_000812"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGC5989765.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            42120..42977
                     /locus_tag="ACIZD4_000813"
     CDS             42120..42977
                     /locus_tag="ACIZD4_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC5989766.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(43164..43526)
                     /locus_tag="ACIZD4_000814"
     CDS             complement(43164..43526)
                     /locus_tag="ACIZD4_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGC5989767.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(43715..43897)
                     /locus_tag="ACIZD4_000815"
     CDS             complement(43715..43897)
                     /locus_tag="ACIZD4_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989768.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            43872..45311
                     /locus_tag="ACIZD4_000816"
     CDS             43872..45311
                     /locus_tag="ACIZD4_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989769.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(45318..47870)
                     /locus_tag="ACIZD4_000817"
     CDS             complement(45318..47870)
                     /locus_tag="ACIZD4_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HGC5989770.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(47984..49315)
                     /locus_tag="ACIZD4_000818"
     CDS             complement(47984..49315)
                     /locus_tag="ACIZD4_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC5989771.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(49281..50759)
                     /locus_tag="ACIZD4_000819"
     CDS             complement(49281..50759)
                     /locus_tag="ACIZD4_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC5989772.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(51064..52899)
                     /gene="tdc"
                     /locus_tag="ACIZD4_000820"
     CDS             complement(51064..52899)
                     /gene="tdc"
                     /locus_tag="ACIZD4_000820"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HGC5989773.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            53369..54796
                     /locus_tag="ACIZD4_000821"
     CDS             53369..54796
                     /locus_tag="ACIZD4_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989774.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(54888..55253)
                     /locus_tag="ACIZD4_000822"
     CDS             complement(54888..55253)
                     /locus_tag="ACIZD4_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HGC5989775.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(55250..55615)
                     /locus_tag="ACIZD4_000823"
     CDS             complement(55250..55615)
                     /locus_tag="ACIZD4_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HGC5989776.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(55807..56055)
                     /locus_tag="ACIZD4_000824"
     CDS             complement(55807..56055)
                     /locus_tag="ACIZD4_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989777.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            56054..56182
                     /locus_tag="ACIZD4_000825"
     CDS             56054..56182
                     /locus_tag="ACIZD4_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HGC5989778.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            56239..57933
                     /locus_tag="ACIZD4_000826"
     CDS             56239..57933
                     /locus_tag="ACIZD4_000826"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HGC5989779.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            58033..58329
                     /locus_tag="ACIZD4_000827"
     CDS             58033..58329
                     /locus_tag="ACIZD4_000827"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989780.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            58707..59840
                     /locus_tag="ACIZD4_000828"
     CDS             58707..59840
                     /locus_tag="ACIZD4_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HGC5989781.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            59871..60191
                     /locus_tag="ACIZD4_000829"
     CDS             59871..60191
                     /locus_tag="ACIZD4_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HGC5989782.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
BASE COUNT        17621 a        12763 c        10177 g        19656 t
ORIGIN      
        1 tttgacctaa gtattagaga aaaaaacggg aaaatagctc ctcatatttt gccgtttttt
       61 gagctaatac cgaaggtcag ctgattgaac accgtttaag gaagagattg tgaaaaagtc
      121 gcttagtttc gagtattaag aaaaattttg tgaaaatgga tttctacatt tttgcataaa
      181 tttggcttaa taccgagaaa ctggcttttg aataccgttt aaggaagagg ttgtaaaatc
      241 agcggtttga cctgagtatt agagaaacaa acggaaaaat agctgctcat attttgccgt
      301 tttttgagct aataccgaag gtcagctgat tgaacaccgt ttaccaagag gttgtgagcc
      361 taccatttaa ctccgaatca caagaaataa tttcaaaaac aacttctcct gtttttggtt
      421 cggttggctt attatcgaga agtagctact gggagtctat ttatcaaaaa aaggaatgcg
      481 acataggtca cacccctttt ttattttctt tgaaacatct ttcggtactc gacagcatac
      541 aagacaaaag attgtaaaag accgtaagtg atgacggcaa aaatgactct cacccacagc
      601 gttggtaatt ctgggaaaag cagcaaaagg atcatgccaa catagatgac agcagtcgct
      661 actttgccat accacttcgc tccacttaat ttgatatttt tagatagccc gattaatcca
      721 gctacaaaca taaagccttc ttttatcaag aatagaccaa acaacagcca aagccacggt
      781 cgataccatg ccatagacaa aatcagaaaa agttgtgtca atttatctgc aaacggatca
      841 agcaccttcc ctaagtctgt tacctgatta tatctccgag caatgacccc gtctagataa
      901 tcagacaaac ctgagacaac aatgaccgct cctgctatat aaaatgactg tctcagcaca
      961 aaataaagat aaatcggcag caaaaaaata cggaatatcg ataaaagatt cggaatcgtt
     1021 tgtatttctt tacgccagtc tgtgcttaat ttcattttat cgccctacct cctcagcact
     1081 cttttctttt tattttagct tacacgggga ataaaaccaa tgatttcact gtttttattt
     1141 ttctttacag acactgatat tatgagctaa tttgagataa tcacttgctg ttttcatcgt
     1201 ttactcttct ttcttcctgt cgtttgcgca tttcttttac tagtacttta tgagcttttt
     1261 ttgatcctcg ctctaggtca cgctgccgtt tacgtgtttt ataatcgata aacagactgt
     1321 ctaaatcgta acctgtcggg tacagatctt ctgctgaacg caccagacga acacgctgac
     1381 gaggcacgtg gattattttt ttgtctaaat atacatcaat cgtatcttca cctatatctt
     1441 cataaactaa cgcttctttt tggtattcat tgacaaatat ccgatcacct tttgcaaaga
     1501 gctgacgttc ttttttattc tccttcctat ttgtaactgc tgtcttagga agaaattctt
     1561 ttttctgtgt ccgataggct ttttccgcca agtaacgctc tgcttgatgg atcaatttca
     1621 tcgacatatc cattttatga gcaatccaca aagcttggct ttctcctgtt tcttccaacc
     1681 cgcaactgat atttaggacg aagtgcttcc cgatcgaaag ccatagcagc cggcacaaaa
     1741 tcttcatgat ctccggcgaa tttcttgatt tctccataat gggtcgtggc aatgatcaat
     1801 gccccttgct catacataga ttccatgatt gcgatcgcta gtgcagcccc ttcatttggc
     1861 tctgttccac tgccaatctc atctaaaagt accaacgtat tcctttttat ctttttcaaa
     1921 atagcagcga tgttttgcat atgaccagaa aatgtactca acgcattttc taaattttgg
     1981 tggtcaccga catcgacgaa aatctcatca aagacagcaa gctctgtccc ttcttttgcc
     2041 ggaacttgca taccgaacat cgccatcaaa gtcaataaac cgactgtctt caacacgact
     2101 gttttgcctc cggcatttgc tccggtgata atcaagcctc gatagtcttt accgatttca
     2161 acatccaatg gtaccgcatg ctcaggtaaa aatggatgtc tgccttgctt gataatgata
     2221 tgttccgatt tattgattct aggtgtgctt ccattgattt ctcggctaaa ttttgcccga
     2281 gcaaagatga tatctaacac cgtgatcgtt tcgatcaata aatcgatcac ttcttcgttt
     2341 tctgcgatag caccagtcaa tgccgccagg acttgatatt cttcactgat ttcttcagct
     2401 tttaacaact gatagtgttc attcaattta gaaatcacag ttggttcaat aaaaaccgtc
     2461 gttcttttat ttgattcatc gataatcgtt ccatctattt tatttttata gctggctttg
     2521 ataggaatcg tatagtattc gcctttttga acaatcattg cttcttggat catttctttg
     2581 tttttcggat gacgcaagaa tttcagtaat tttgactgga tttctttttc gattagttgt
     2641 aattgtttgc gtactttacg caaattacgt gacgcgtcgt cactgacttt attatttttt
     2701 attttctggt caatcaactc ttctacattt atcaaatcag gaagatgttt gctataagca
     2761 aacaacaagg gtgtctggta ttgattctta tcaaaaaact ttgtgatcat ccgactgctt
     2821 ctaagaaaat ccgcatattc gatcaaatcg gttggctgca gaatcaaccc ttttttgact
     2881 tgttctgtca gtgcatcgat cctcggcaac cccataaatg gaacatgctg actgctttct
     2941 aagatcaagc gtgcttctct tgtttcttct tgacgatcca agacagtttg taggtttgtc
     3001 gagaccgtca tatcgctgat tcgttttttg ctatagtttc caattgctct tgcttggatt
     3061 tcctttttga tccgatcaaa ttgtaattga ctaatcattt cgttgtccat attctctcct
     3121 tttcttgaag agatacctgt cccaaaataa ataagggcct agagataaat aaaaggatag
     3181 aacacagctt aaaaaagtca tgtcctatcc ttattagaat acaaagatat tgttttcctg
     3241 acaggtaccg tttcataagc acaccaaata aactttgttt attggctatt cgacttactg
     3301 attagatacc agctacactc acaaaacata ccccattctt ctaggtctta tttattttcc
     3361 acttaactat agcaagacac attttggttg tcaaacttta gtatgtttta tagatttaca
     3421 ccattaatga atagacacct accgcgataa ttgctccgat cattggacct gcgattggta
     3481 cccatgaata tgcccaatct gaagttcctt tattagctat tggcaatacc gcatgtgcta
     3541 atcgaggacc aaagtcccga gcagggttga ttgcatatcc tgttggccct cctaatgaaa
     3601 gaccgatggc taagatcaat ccacctacag cgaatacgtt cgttccaggt gcaaattcgt
     3661 tttgtccaaa agctagcaac ccaagaacta atacaaatgt accaattaat tctgtgatca
     3721 catttgctgg ataattccgt atagcaggac ctgttgcaaa cgttcctaaa atcgcgcttt
     3781 catctttcgt tgcattccaa tgtggcaaat aagaaagcca aacaagaatg gcccctgcaa
     3841 aagctcctaa aacttgcgca atgatgaaag gaacgacaag attccaacta attgcccctg
     3901 tcatcgccat agctagagag actgcaggat tcaaatgagc tgggcccatg aatccagaaa
     3961 tatagacagc cattgttaca gcgagtcccc aaccaaatgc gatgacaatc cagccagaag
     4021 cctgtgcttt acttttgttt aaattcacag ccgcacacac accatctcca agcaaaacta
     4081 ggatcagtgt cccaataaac tcccccatga tttgagtcat atcactgttc atttatttct
     4141 ccccctttag ttcccgcaga tctgattctg caatcaatgc ttctaaacgt ttagtctgtt
     4201 gcgccttctc ctcttctgtc cattcaaaat atccagcaat tgcatcgatc acaggttgct
     4261 tgatctcatc aagctgatct cgttcaaaca acagatgatt tgtacgacga atgagataat
     4321 cgcctggggc caaaaccatt tcttcttcta aaccataacg taaccgagct gactcagcga
     4381 gactcaaacc aggataaggt gccatttctt ttgctaattc aaagatacgt cgggcattag
     4441 tcccgtaaaa atcagcgata taagtagcat cttcttcctc taaaccggct gctactcctt
     4501 cttttgctaa ttctgtcact gtttcttcta atttagttgg atcgaagttt ccacctgaaa
     4561 tctgatattt tttagagtcg atttctttcg tctctattcc gtattcttct tttaataatt
     4621 ggcgtatcaa tcgcaaagct ccttctgcca tcttacggta atcggtgatt ttcccaccag
     4681 ataaagtcag caaaccatct ggttctcttt ctaaagaact acctctggaa atcgtagaag
     4741 gtgctttttc atcacggctg ttttccaaat ggttcaacac gtcttctact tcagcacgag
     4801 aaactttgtt ttccttatat tcacttactg tatcgacaac tttattgaag ctcttgtctg
     4861 aaatcgatcc attatctcca ccattgtaat cagaaccaga attaccaatc aacagtggac
     4921 gaagtcctgc ccagcttgct tcgatatcat tcaatgtgat atttgcttct ggatagcgat
     4981 gattgatcac atccaataga taatctacat cttcttgtgt gactttcgga tccgtaaaat
     5041 ctccttggta atccgtatct gtcgtaccaa agtaagtctt gttttctctt ggaatagcaa
     5101 aaaccatccg cccatcttgc tttcctgtat cgaagtatgt gggttgcggt acaggcagtt
     5161 ttttcgcatc tacaactaaa tggatccctt tagttggacg cattttagga gagactggac
     5221 gcgtaaaatt caagtttcgt actttatcta cccaaggacc actcgtattg atcactaatt
     5281 ttgctttgat ttcgatcact tcatctgtca gcaggtcacg agctttgacg ccaacgattt
     5341 gatcgccatc atataaaaag ccaaccgctt tcattttact tactagataa gccccatctt
     5401 cggcagcctt tttgatatta tcaatcacta aacgggcatc attgttgcgg aaatctagat
     5461 agacacccgc gccttttagc ccttcttttt tcaaaaacgg ttctctttcc aatacttctt
     5521 ctggtgtcag cgtataattc tcatatttgg ttcctgtcac atttgccagt ttgtcataaa
     5581 ggtccattgc tactttgacc gagaacatat tgaaggttgt tgctccttcg ccctcataga
     5641 ttggcaaaag cattggatct ggttttggga tgtgtggggc aatactttgt acgactgcac
     5701 gttcaccaac tgtgtcagct actacttcca catcaaatgt cttcagataa cgaataccgc
     5761 catgaacaag tttggtcgag cgagaggaag tcccttctgc aaaatcctgc atttcgatca
     5821 atcctgtttt gattcctgat gctgctgact ggactgccac accggcacca gtgattccgc
     5881 caccgatgat caacagatcc aattcttctt gctgcatttt ttgaatgcta tcttgtcttg
     5941 tcttgtttga aaacatatgg atttcctcct tattcaaatg cttgggtagc ttttactgct
     6001 tttttccaac cgttgtaaag tttttctcgg cgctcttcct ccatttgaac ttcaaatagc
     6061 ttgccagctt cataaaattc gcggatctcg tctgtatctt tccaataacc gacagctaat
     6121 cctgctaaaa atgctgcccc tagcgccgtt gtttccaagt tttctgctcg ttggatcggt
     6181 acattcaaga tatctgtttg gaattgcatc agatattcat tgtttgctgc accgccatct
     6241 actttcaata caggaatctt gattccagtg tcatcttgca tcgtatcgat gatatctctc
     6301 acttgataag caatcgactg taaagtagct ttaatgatat cttcttttgt cgtaccacgt
     6361 gtcaagccaa acatagcccc tcgtgctgcc tgatcccaat aaggagcacc tagcccaacg
     6421 aatgcaggaa caacataaac ctcatcttcg cttgtagagc gtttcgctgc gtcttctgaa
     6481 tcgctagctt tttgcaacat ttgaagtcca tctctcagcc attgaatcga agaaccagcc
     6541 acaaaaatac ttccttctaa agcatagtaa acctttccat ttatgccgta accaattgtc
     6601 gtcaataaat tatttttgga taattgcggt ttttcaccgg tattcatgac aataaatgaa
     6661 cctgtaccat aagtattctt gaccatgcct ggttcgaatg ccatttgtcc gaataatgcg
     6721 gcttgctggt ctcctgccat ccctgaaatt ggtgcttcgc ttccataaaa atgataacct
     6781 tgcgtataac cataaacttc tgagttagaa gtgacttttg gtaacatcac tcgaggaata
     6841 tttagtaaat ctaaaatctc ctgatcccaa tctagctgat ggatattgaa caacatcgtc
     6901 cgactggcat tcgagtaatc agtaacatgt gcttgtccat cggtcagttt ccatactaac
     6961 caagaatcga tcgttccaaa catcaattcg cctttttcag ctcgttcttg cgcgccttct
     7021 acatgatcaa gaatccagcg tatcttcgtt gctgagaaat aggcatcgat cactaaccct
     7081 gttttttcgt ggaaaaattc ttgatagcct tcatttttta agttatctgc aattccagct
     7141 gactgtctgg attgccaaac aactgcatga tagattggac gtcctgtatc tttttcccat
     7201 attactgttg tttcacgctg gttcgttatg ccaatcccag caatctgatt tggtttgatc
     7261 cctgattcga tgaacgctcc ggcaataact gactgtacag aattccagat ttcatttgca
     7321 tcatgttcca cccaactttc ttgcgggaaa tattgcgtga actctttttg agaactgccg
     7381 atgtgtcttc ctttcttgtc aaagataatt gctcgtgagc tagttgtacc ttggtcaatc
     7441 gccatgatat acgttgattc tgtcattgtg attccctcca ttatatgcaa acgctttctt
     7501 taactactct tatcatacta ctgttttaaa aaaagaaact gtcaaaattt tattcttttt
     7561 ttcttttttt gacagttttt tattatgaag ctatttttta atcaattctt ttcttttttc
     7621 agcgtctcta ttcttctttt caatcgaata atgtcgtaag gtgacgcaaa ttctgacaga
     7681 taatattcac actgtttttt gtttctctgg caaaatgtga tcaccaaatc atattcttta
     7741 ccttcttcat aacttccaat ctcaataccg ccgattcccc tcagttctct gatcagatat
     7801 tgttgaaaag caatacgata aatcggcaga ctttctaaat cgattccaat cactactggt
     7861 tttgcaatat aaaaatcgat catcaaaaga acattggcat actggatcat caggtaacta
     7921 agctcactat cttcagctct tttcctcggc aattgctgca ccgctgtttc ctgtaatttc
     7981 gccagtaact gtgttaagga atgcccgagc attttctgct gctgttccaa aagccgatca
     8041 cgctcataga cttcgatctt tccaacaaag aaaaaccatt cattgttgat ctgggaaatt
     8101 tggtagccta ctgccttttc ttctttgatt ttcaaacgac gaggacgata atgccataac
     8161 atcgtttccc gaatgtaagt atctaaaaca gcggttggta actttttgct ccgtgtcaaa
     8221 tcatactgat aaaatatttc ttcgtctact atcgaaaaag aaacaaaaaa gctgtaaaac
     8281 atcattgttt cgtatacatt cagttctgct gctgttcgac taagatgcat cacgatgatt
     8341 ggatcgattg cttgataaag ccggtccgac tgatagagta atttcttttc tttcaaagtt
     8401 gcgtacgtac ttttttcatt caatagtctt tttttcgtaa tcccgagcca gcaagcaatc
     8461 tgtgcttctg ctgatgccgt aaacgttgtt tctaatacac ggtccaatcc tagaatgaac
     8521 ggtctttttt ctggtgtatt ttgcaaaaaa agcggtcgct gatcttccgg gatatattgg
     8581 aatagttcat aataaaaata tcgtatctgt agctcttctc cgtataattg accgtttttg
     8641 atttgtaatc caaattcctc taagagctgg ttcaattctt tgatctttcg aaaaacagaa
     8701 gactcactga tattaaacgc tgtcgctaat cgaacgatgg atacttgctg atgttctaat
     8761 aaatagacga gcatcttaaa cttcaagctt tcctgcaata aaaacaatag aattttttcc
     8821 aaacttacat cttcgtccaa cacaagcagc gcctgatact catttcgctg tacttctact
     8881 tttttttcca tcattcggcc aatcaattca atatcttcca aatattgatc aaacgaggct
     8941 tttgacagtt ggacatgctc tctcaaacca ttgatagagg ctgttccccc ttgcagaaca
     9001 aggtttcgca aaatcaggat ctgtaactgc tcttttcttt ctaataatgc ttcaatcttc
     9061 ataggcagta ttcgccacct ttgaccacac catatctggc acacggtatt ctggctggaa
     9121 aaatagctca tgttcttcta actgttcaaa cgtccatcct tcttctactg caattgtcag
     9181 ttggtcaaga aggtggaaca tctctttttt gctttggagc tgtgctccaa gaatcttttt
     9241 ttcagaatca aatagaaatt tgagtttaac tttgctttga tttattgctg taagcttgta
     9301 gtctacgtat cctgtttcaa ttttttgggg ataaaaaatg ctctcttctt ctgtcaaacc
     9361 tacgcttcct aagaaatagc caaaccactg attgccgact ggacgatagg ttccctgatc
     9421 ctttgtctgt gagccactaa ttgtcttgct gacatttcgt gctgtacgga cagcgttatt
     9481 tactagagaa acatacattt tttcatttgt tggacgaaaa gttacttgga tcgcatcgcc
     9541 aatcgcataa acgtcttttt gagacgtttg caagtagtca tctacccaga tcgttccatc
     9601 atcattcaat gttaattgtt cttcccacat ctgattgtcg ggacgagaat gattagccag
     9661 caaaacaaga tcatagttct cctttctttt ttccgtctct acaatagcgg tttcattttc
     9721 ggtcaaagac acaacttgtt cttctaaaaa aagtgaaagc ccttgatttt tcatttcctt
     9781 tactaacggt tctgtcattt caggatctag ataacgaaaa agaattgact ttcggctttc
     9841 gtaaagatgg atttgttttt ttcttgatgc caacccttca gctatttcga ttcctgcttg
     9901 tcctgcacca ataattgcaa ttttctttgc attcatgatc ttttgctgaa gagccgttac
     9961 gttttgtatc tttttaactg ggtgaataag cgttgattct gcagaaatat ttcgaaactt
    10021 ttgatttgaa ccagtcgcta gaatcaaacg atcaaaatcc aatttttttc ctcctgctaa
    10081 aacgactttt ttttctttca atcctattac tgtcttttct gtgtaaacat ggattcgata
    10141 gcggtcagtc agttcttctt tcgtgatcca agaaagttgt ttttcactgg taacctttcc
    10201 ttttaatatc aaattgaacc cgctgggaat ccatcctaac ttcgattgct tttcaatcaa
    10261 atatatttca cttgttggca tcaattggcg aagataaata gccgcatgaa tccctgcaaa
    10321 cgacccgccg acaattacaa tgttcatctg cattcctctt tcttataagg tgttctactg
    10381 ctaacttctc aatcagaaaa cacagtattc ataactcgct ttcaacctta tgatacatag
    10441 cgatgcagca gaatcaaccc tctccatcat accgtgttct aggtctgctt ctcaataatg
    10501 tactagtgga cctaattgaa gagtatcatt tctgaagaga tgtttcaaaa aatgtactct
    10561 tataaaagaa aaaaactcgc cttttacgta cctctgtcca aataggaaac agaaaagaac
    10621 gaaaagacga gttttagcgt gtgtaatgta atagttagaa tagacacatc atttattttt
    10681 aattctttaa tgcttcaaca actgcttcgc ctaattgatg agcagattga ggattttgcc
    10741 ctgtaagaag ccgcccatca atttgaacca cttctgaaaa agctgctcca gactgatagt
    10801 ttgctccttt ttctttcaaa gcatcttctg ctaagaatgg tacttcattc gttgtaccat
    10861 ttgcttcctc ttcttcatta ctgaacccag tcactgtacg tccagctaaa atagattttc
    10921 cagactcatc tgtaactggc aacaatccta caacaccgtg acaaacagct gagaccagcc
    10981 cttcatttcg atagatttgt gaagcgactt tcccaagatc tattgcttct ggaaaatccc
    11041 acattgttcc gtggccacca gcataataaa ccgctgcata atcatttgca tccacatcat
    11101 caggacgtaa ggtatttccc aaggcccgat ttctgaaatc ttcatcttca taataggccc
    11161 aatcgatttc atccatattc aaaacacttt gcggttctaa aggtacatat ccgcctttag
    11221 gactgacaaa atctgcatcg atcccatttt ttactaatac atcataaaaa tgagtcagtt
    11281 cacttaacca caaacctgta ggacgctcga tcttttcgta cttttctaca tttgttaata
    11341 cgatcaatac tttcattttc ccatcctctt tctataaaaa ttgcgttatt gataacgtgc
    11401 tttcaagaaa ttatataatg ggcttggcaa ataaagctct ttatatgctt cttcaaaagg
    11461 tttcgttaca aattcatcct cacggttttc caataatttc tctgcccagt caggatcgac
    11521 gatcatttgc tgtccaattg ctgcaagttc tgcatatttc aatacctgct ctacatcttc
    11581 gcgattgcgg atcccaccga caccaactaa agggatcttt ccttgaatcg tgttatggac
    11641 cacttcaaga atcgatttat cgttgtattt atcagaacga gctattcgat catacatatt
    11701 taatgaaaca tgcagataat ctagttttga ctcacgtaat cgttcaagaa gccagatcgt
    11761 gtcttcaaaa cggatacctg gtgtttcata ttcttctggt gagaaacgat accctacgat
    11821 gaatggtttt ttagcatatt gttcaaccgc tgagaaaacc gttgttaata attcttcaat
    11881 aaaacgataa cgattttcca agctaccgcc ccattgatcc tctcgtctat tcgaatgcgg
    11941 agagaaaaat tgttggatca aatacgtatt tgctccatgc aactcgattc catcaaatcc
    12001 tgattcaatc gctctacgtg tggctttgcc aaatgcttgg attgtttcaa cgatttcttc
    12061 ttcactcatt gctcgtggtg tttccgcatc aggacgtttt gctgcaactg cacttgcaga
    12121 tacaggctgt tctccagata aagttgctcg acttgtcatt cgtccaccgt ggaaaatctg
    12181 aataatcgct tttgcgcctt ctccttggat tgctttcgct agctcactta atcgaggaat
    12241 catttcatca tgagcgatgc tgagttcacc tggccagcct tttccgatat cttggacatt
    12301 tgcagcacca gtaataacag caccaagacc tttagaacgt tgtttataat aagtgatctc
    12361 atcttcggtg atcactccat tgaaaaagct gagttgtgtc gtcataggcg acagcatcaa
    12421 tcggttcttc aattgaactc ctgaaggtaa agtaattgat tgatcaaatt gtgacattgt
    12481 cattcctccc ataattcgct ctgattaacc tatcgagaat catctatcat taaaccactc
    12541 gattagttgt acatgcaact aatttgctta aaaaatttta ttttttttgt aacttatctg
    12601 ttgcatcatt cattgtctgg gctaattctt tacttgcttc atttcccaaa actgctttgt
    12661 atgactgatg aagttcttcc cagctaccat cgacttcctt agcaaattgg cgtccttgtt
    12721 ctgtaagata aactaatgac aagcgacctt cgctaactgt tttgacgtat cctttatatt
    12781 ctaatttttc aacaaaacga gcaatcgttg atggggcgga atagagcatt tgtgcaatat
    12841 ctttttgtgg tattccatct ttttctttta atatcaataa aataaaacca taagttggtg
    12901 ccagacctgt ccttctaaac gcttcatcag ctaatttatt caacatgcga tctagctttt
    12961 tcacgctaaa gaaaagacat tcatctaacg ctttttcaat tggcttttcc atttcatccc
    13021 ctccattggc gtacatatca tagtatgatt tttatttttt gtcaaaaaac acggaataat
    13081 gtccgcctcc tctgtctaga tttgaaaaaa agaagtagcc atcttcaaag aatttcggct
    13141 tgttttcgac aaaactcctt ctggaacacc gtgaatcaga ggttgtgaaa aagtcgttta
    13201 gttttgagta tgaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaatttgg
    13261 cttaataccg aaaaactggc ttttgaacac cgtttatatc agaggttgtg aaaaagccgt
    13321 cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt gtcgtttttt
    13381 gagctaatgc cgatggtcag ctgattgtac accgtttatt gagaggtcgt gagcctgccg
    13441 ttgaactccg agtcacaagg agcaatttca aaaaacagct tctcatgttt tatgactatg
    13501 gtgacttgtg atcgaggagt tggcaggaga atactgttta ttcgtaaaga aggggctgtg
    13561 acaagacttt tgtcacagtc ccttatttcc ttttattata ggatttcgcc atttgattgg
    13621 atgacttgtc tgtaccaatc aaatgatttt ttctttaacc gtttctttgt gccattccct
    13681 tcgtcatctt gatcaacata gatatatcca taacgttttg acatttgtga agtagaagcg
    13741 ctgacgatat caatgcagcc ccacgacgta taaccaaata aatctactcc atctttgata
    13801 gcttccttca tctgctcaat atgctgcttc aaatagtcaa tgcggtaatc gtcttgaacg
    13861 gttccatctt cttctacttt gtctatagct ccgagtccgt tttcagctat gaacagtggt
    13921 ttttgatacc tatcatataa ttgattcaaa gcaattctca aacccttagg atcaatctgc
    13981 cagccccatt cacttgatgg aagatacgga tttttaattc ctccagttat taagtttcct
    14041 tggacccctt cccaattttc tggatgagca ctgactgcac tagacatgta gtagctaaaa
    14101 gaaacaaaat caacagggta ggctgctaag atttcttcat cacctacttc tatttttaag
    14161 ttgacacctt tttcttcaaa cattcgttgc gtatacgctg gataatatcc tcttgcttga
    14221 acatcactaa agaacaaaga agttctttgc tgctcaattg ttttttgaat atcatccgga
    14281 tcacaagaat acggaacaag aagctgatag ctgatcatac aaccgacttg tgaacctttg
    14341 ataatttcat gacaagcttt tgtagctaaa gcacttgcta taaactgatg gtgtgcacct
    14401 tggtatttcg cttgttccaa atggggatgg ttttcttcaa ttactcctac gctaacaaaa
    14461 gggtgatgtt ttacacagtt gatctcattg aaagtcatcc aatattttac tttattttta
    14521 tagcgtttga atactgtttc agcgaaacga acgtaaaact gaataagctt tcgattaggc
    14581 catccaccat attctgtaac caaatataac ggcatttcat aatgggaaag agaaacgact
    14641 ggctcaatcc catattttag acattcgtca aacacttgat cataaaaaaa taatcccgct
    14701 tcattgggtg tttcttcatc accatgagga aaaattcttg tccatgcgat agacatccga
    14761 tagcatttaa aacccatttc agcaaataaa cggatgtctt ctttaaagtg atgatagaaa
    14821 tcatttccgt gtcttttagg ataataatac ttgctgttgg gatcctgcgc cgcttttact
    14881 tgctgatgcg tcatcatatg ccattgatct gtccattttt ctttaggtaa atcgctgtcg
    14941 aatgtataca catcagacac agataatcct ttttcatcta catcccatgc accttcacat
    15001 tgattggccg ctgtcgctcc gccccataaa aatccttctg gaaatttttt catatcgatc
    15061 cccctaaact tgctagtttt cttgtttgat tatttttctt atgactagta atgatatttt
    15121 tgaatctact actatttgta acaataacca ttgtggtcgg atcatatccc tctttgatta
    15181 attcttgcaa atctacttcc atcaataaat cgcctttacg tacttttttt ccatcagata
    15241 ctgcactttg aaagtatttg ccatttaaat tcactgtatc aataccgata tggatcagta
    15301 tctctgctcc ttcttcactg actaccccaa ttgcatgttt cgttggaaaa actgttgaaa
    15361 cttccccgtt tacagaactg tagatttttc cgtccgttgg aatgatcgca aacccttctc
    15421 ctaaagatcc actagcaaat gttggatcgt ttacttcaga taaatcaatt atttcacctg
    15481 ctgcaggagt acttaacact atatcctttg aggattcttc ttcgatttca tccttgtagc
    15541 cgaaaagaaa agttagcata caggaactga tcatcgctaa gaaataacta gcaactagcc
    15601 aaacaaatcc ttcaccaata taaatcggga aagacaaaat acttcttgta gcaactgcca
    15661 aagcaccggc tcctgcggca ccagctactc caccaaatat agctccacat atacaagcaa
    15721 tgtaaaatgg tcgtttatat ttaagagtca caccataaac agcaggttca gtgattccaa
    15781 ataatgctgt gataaatgca gataaagata aactttttac tttcttattt ttcgttttca
    15841 aaaatacccc aagtactgct cctgcttgcg cagctacggc agtcatacat gctggaccta
    15901 gcgtatcacg accgtagaaa gaaagattgt tggtcattac tggtacaagt ccccaatgta
    15961 acccaaaaat cactaacact tgccaaaatc cgccgataac agcaccagat aaaacagggc
    16021 taaagttata aacagctaaa tatccagctg caatcagctg acttgcataa tctgcaattg
    16081 gacctacaac taataaaata attgggacca tcacgatgat acaaatgaat ggtgtcaata
    16141 aatttcgaat actttcgtgc aagcttttgc gaatcttagg ctcaatataa gaaagaaccc
    16201 atacagctaa aattgctgga ataaccgtac ttgtatacct tgctagaatc acgggcatcc
    16261 ctagaaatcg caaggttatg ctatcactat atgcactgac aatcgtagga taaacgagag
    16321 ctgctgcaat aaccatagcg atgaaacgat ctgtattgaa cttttttgca gcagtatatg
    16381 ccaaaaatat aggcaagaaa tagaaaaatg catcagctgc tgcattcaaa atgatataag
    16441 ttcctgattc agtagttaat aaattcaaac tcgtacataa ggcgagtact cctttgatca
    16501 aaccacttcc tgccaagacg cctaaagtcg gggcaaaaac agcggcgatc atgtctataa
    16561 aagagtttaa aatgcctttt ttctcagttc ctctctttcc actagatgca tcatcttcta
    16621 gtttcatttg tttggataat acgtcataca cttcatttac tgcatttcct actacgactt
    16681 gaaacattcc tccagcttcg actacagtga tcacaccttc tagttgctct accttctcct
    16741 tatctgcctt cttattatct tttagggtaa agcgtaacct tgttgcacaa tggtaaacat
    16801 tgctgacatt ttcttcgcct ccgacaaatc ggacaatatc tttcgctaat tgtgaatagt
    16861 ccatttttac ttcccccttg ttaattaatg ccgtagcaat ccttcttaca agataagtat
    16921 agttcttaga aaacggtttc tccattcaat tagtacccct tctaatagcg aacgaaactg
    16981 tacaatagtg tgtatggttt acttagccga gcaaatcact cactgcttga aagaaaacaa
    17041 gtatatcgtt tctcttatag tcaaaggaga caaaaaaaac acgcttgatc ttcctttgct
    17101 gatgtataag tggtatctca agctgatact ctgtgatttt tgtttctact tggcttttga
    17161 taagacagca caacaaagtc tcggcattta acggaagcat aactaggtca gaactaggag
    17221 agattagttg ctgaatggaa tctatctttt tatggatttt tatttgattt tcttctttgt
    17281 agtaatgatc aagcagtttt gttttctttt tttcttcaac tatggtcagc ttttcacgca
    17341 aaatctgata aatctcccaa gattcaaact catctagaac actaggtaga taaatcaaat
    17401 catcccactc aaaaataagc tcttgctcag tagtcaaaat tgcatcatat tccgttattt
    17461 tgtttgattg atttttgaaa agatacactg gttctatccg gcattctttg atccacatgt
    17521 tcatactttg ttgaatctgt ttttttagtg tattcaaaat actaattggc tggttactaa
    17581 caatcagtat ctccccttgt tttcgaaaag gattcaacgc ttcggcaaga tacaaaacaa
    17641 aataagcgct ttcagctaaa ttgggacgta attgaaaatg tattgggaag aaacgccgaa
    17701 ttaaataaat ttctaaagga taacgggaga tgatcttttg tacaaaatga ttcatggtat
    17761 tatgtccggc atccatcctc gttttcattt gtttgatatg ggttagcaaa aattctgttt
    17821 catggaacaa taacgaaaca ggaagatcta aaaaacgaat aatcgtttgc tcaaatgctc
    17881 ttagattctt ctctatttct ttgttttttt catcattaat catcaaataa tttaactcta
    17941 atagtcgatt ttcaattgct tgtttttctt gattggaaaa agaatagggt agttctgatg
    18001 ataacttttt tgtgagggtc tctaccatcg gaataaataa tgtatacctg tttgtttttt
    18061 ctaaaagttc ttctcttcga agaatggtca aaacgagata ccgagaaaat cgtatgaagt
    18121 cctctcctga aacaatataa ttatatgata taagaacctc ttttaatgtc ttttggacag
    18181 tcggcatgat attggaaaaa attgtactga tttgttgagg aaaccttgcg tgttggatca
    18241 ccgtttctgt tccaacaaga gataagaaaa ttctttttga attttcttca gcaatgattt
    18301 ttagtccttt tgtcgacgaa acttccagtt ctaatttagg attgcgctcg atccaacgca
    18361 aaatcgtttt tatttgtaat gatacggctg tttttgaaag aaagaaaatg tctgctatct
    18421 tttgcatact gacataccct ttttgaaaca ataagtacgt cacaatagtt gaagctcgga
    18481 aatccatgct ggaatagatt ttatgtttcg tcacctcttg tatgatttgc tgtttagttt
    18541 cagattcaat tgattctaaa aaataacctg aacgtttatt tgactggata atgattttct
    18601 tctcgtagat agcaagcata tttttgattt cagtttggat cgttttcttg ttggtaccta
    18661 aagcttcagc taattcttcg cttgttatcc aatgattctt atttcttaat actacaagaa
    18721 tttggagttg tcgtttattt aagtccattt gcttacacct cctctttgtt ataaacatac
    18781 aggaaaaacc tctcaaatga caatagtcac ttgcagaggt ttaaaaatca tttgaagaaa
    18841 gatctatatt caaggttttt accattagac tggataattt gtttataata ttcaaaacta
    18901 tcttttttca atctcctaaa gcttccgctc ccatcatttt gtctatccac ataaataaag
    18961 ccatatcgct tcctcatttc ccctgttcct gccgatacga tatcgattgg tccccaccat
    19021 aagtaaccaa tgatttggca accatctttt attgcctcag caatttcctg aagatgtatt
    19081 tttagatact cacaacgttt tggatcgtgg attcgattca attcatctgg tgcttcatct
    19141 agtccaatgc cattttcaac tatgaataat ggtaattcat aacggtctgt caattcattc
    19201 atgacataac gaaaccctag aggatcaatt ggccaactcc aaggttcggg agatttttcc
    19261 ttcaaaaagg gattatcgaa accatttgct ccgccagtat ctacgcgcat ttctgcttct
    19321 tttttataga cagcgctacg ataataacta aatgcaatat aatctgccgt gttagcttgc
    19381 aagcactgtt cgtctccatc taacattact ggtgcacagt cttcttcctt ccatgtcctg
    19441 taaatataag ctggataatg ccctcggcac atgacatcgg agaaaaacca tgaattgcgt
    19501 ttaaattgca gtgaaccaaa tacattctct ggatcacagt catatgcata agtcgctaat
    19561 gcagaaaagc tacacataat acccatctta gcatttggat cgattttctt taataattga
    19621 gtagcacggg cgttcgctag aaacatatga tgacaggctt gataaatcac tttttttgtt
    19681 agtgtagcaa tgggttcaag tttatctcta gcagggaatg taaccaatcc agcagctgca
    19741 taaggcatac gaaaagcatt attgatctca ttaaaggtca tccaatattt cactttccct
    19801 tggtagcgtt caaagacggt ctgcgcataa aattcaaaaa agtcgattaa ttttcgattt
    19861 tgccaccccc catactctcc taccaatgct aagggggttt cataatgact aagagtaatt
    19921 actggctcga tatcatatcg atttaatgta ttgattagtc tgtcataaaa tacgagacca
    19981 gcctcatttg gcttctgttc gtctcctctt ggaaatattc gtgcccatga gatgcttgtt
    20041 cgaaaagctt ttaaacctaa ctccttcagt aaacgaatat cctcttcaaa tcgatgataa
    20101 aaatcaatcg cttcatgaga aagataatgg agtgattcgt ctaaagcaat ctcccaaatc
    20161 tttttttctt cattccactg aatactagga tgctggttca tgatcccgat aagcgtatct
    20221 gtcacattag gtaatttgcc gtcttccaac catgcacctt cacattgatt agcagctact
    20281 gctccgcccc ataaaaaatt ttctggaaat atttcctgat ccataactat ctctcctcgc
    20341 tatcaacaat ttcttacttg aagtatagct cgattcatca aaacaagata ttctaactat
    20401 ttcggcagaa gagaagaaaa aaattgaatg ctactcttca tttttaatat ttatatataa
    20461 caaatacata agacgatccc cgaaagaaaa cactcgttaa ccatctaagc aaacgattta
    20521 ttttacttcc aacacaaatg cttcataagg tcgtaaatca actttgccgt ctggtaactg
    20581 tttcagagga taatttgaca caataaccct taaagcttca cgtggaatag tgaacgtctg
    20641 cttttcactg gacatattac aaataacgag ccattgctgg tcttcatata tgcgagaata
    20701 ggcaaagaca tgctcaggcg tcttttccac taattcatag tctccccaga cgatgatgtc
    20761 atgttttcta cgcaaatcga tcaatttctt gtacatataa aaaacagaat cttgatctgc
    20821 taacgcttct tctgcattga tttctttata atttggattg actcgaagcc atggaattcc
    20881 agtagtaaac ccagcatgtt cacgggcgtt ccattgcata ggcgtcctag cattgtctct
    20941 tcctttcgcc ttgattgatt ccaagatttc ctcttttgta aatccagaag aaatcctttc
    21001 gttatacata ttgattgtct caatatcttt tgcttccgcg atatcatcga ttgggcaatt
    21061 cgtcatgcct aactcttctc cttgatagat ataaggggtg cctttcatca tatggagcaa
    21121 gatagcaaac atcttggcac tttcttttcg atacacatcg tcatttcccc aacgagaaac
    21181 aattcgcgga agatcgtgat tattccaaaa taaactattc catccttcat cacctaaaga
    21241 tgtttgccat ttggataata cttttttcag ttcagagata ctcaagggtt tcaaatccca
    21301 tttgtctttg ccttcttgct gatctaatcc tatgtgttcg aattggaaga ccatggataa
    21361 ttcatttctt ttaggattgg aataaagttt agcgatttcg gtagttgctc cccatgtttc
    21421 gccaacagtc atcagatttt tgtcaccaaa agttgcttga ttcatttcct gaagatactc
    21481 atgcagttta ggtccattac ttgtgatttc tttatccggt tctttgccaa tcatatcgat
    21541 cacgtccata cgaaagcccc caataccttt atcgatccag aaattcatca tttgataaat
    21601 ctcttggcga acctgtttat ttttccaatt caaatcaggt tgacgcttgc tatacaagtg
    21661 cagaaaatat tgccccgttt tttcatccaa ctgccaagca gaaccactga atattgagcg
    21721 caatctatta ggctcttttc cattgaccgg atcacgccaa atataatagt cccgataagg
    21781 attttcttta tttttacggg cctcaatgaa ccacggatgt tcatcagaag tatgattcac
    21841 caccagatcc atgatgatac ggatatttct tttctttgct tcttcaatca gttcttccat
    21901 ttcttccatc gtaccgaatt ctgccatgat tgcttgataa ttactgatat catacccatt
    21961 gtcatcattc ggagactcgt atactggaga aagccaaatt gcatcaatac ctaaatacgc
    22021 cagataatcc aacctggaaa taatcccccg caaatctcca ataccatctt gatttgaatc
    22081 ttgaaaactt cttggataga tttgataaac aactgaatgg tgccaccatt tttgttccat
    22141 gattttcctc ctataaatgg atgtttctat tttttgctta atcatttatt ttagtctctc
    22201 tcactaaaaa ttgtaacgct ttcaaatagc tattgcacct tgttatcggt aacagaataa
    22261 aacaaaaaaa cagctgagga aattccctca actgtttttt gaaaggattg atttatgcag
    22321 ggaagaatgc tgatttcaca acttctttat aaacggtgtt cactcagctg tcccttggta
    22381 ttagctcaaa aaacggcaaa atataagaaa ctattttttc gtttttttct ctaatactca
    22441 ggccagaacg ctgatttcac aacctcttta tttcacattc aatatccaca tgaatcccac
    22501 aaatacaaag aacagaccat acatgattgg agatacttct tttcctcttt tagctgctaa
    22561 catggtaatt ggatagaaga taaaacctaa tgcaatccca tctgaaatac tataagtcaa
    22621 aggcatgccg atcaagatca agaatgaagg gatcgcaatc tctaagtttc cccattcgat
    22681 ttgtcgcaaa gattgtgcca tcaatactcc taccataatc aatgctggtg cagttacttg
    22741 tgaagtaaca actgatagta atggagaaaa gaacaagcct aacaagaaga aaatccctgt
    22801 agtaatagct gtgatacctg aacgtcctcc aacggcgata ccagctgatg attctacaaa
    22861 tgcaccaaca ggagaagtac caaataagga acccgcaagc atagctgttg aatcagaagc
    22921 taaagctttc cctacacgag gcatcttgtt gtctttcatg aaacctgctt ggtttgctaa
    22981 tccaactaaa gttcctgctg tatcaaagaa agtcacaagc aagaatgtca gcactacgac
    23041 ccacatttga agagaattga tgtcccctac atgttttaat gcaactaaaa atgttggttt
    23101 caaacttggt gctgcggcaa caatttcaga aggcattgga atcaaacctg tgaccagacc
    23161 taaaatcgtt gtagctgcca tcccgatgaa gatgccacct ggtacacgcc gaacaagcaa
    23221 gatagcagtt acgactaatc caaaaatcgt caaccaagta gaaccaacgt tgagtgatcc
    23281 taatcctact aatgtagatt cattcgaaac gatgatccca ccttcgctca gaccaaggaa
    23341 agcgataaat agaccgatac cgccagaaat cgcatatttc aaatctgctg ggatcgcatc
    23401 aatgatcatt tcccgcagct tgaagattgt gatcaaaata aaaatcaaag aagcaacgaa
    23461 tacgccggct aatgctgttt cccatggaat ccccattcct aaacaaacag aataagcaaa
    23521 aaaagcattg atcccaagag caggtgccgt tccaattgga taacgggcta atacccccat
    23581 taaaacacag ccgatcgcac tggctaatgc agtcgcagta aacactgctc cttcatccat
    23641 tccagaagca cctaatacag ttggatttac aaataagata taagccattg agataaatgt
    23701 tgtaaatcct gccagtacct cacgttttac cgtggtgttc aatttttcta tttcgaagta
    23761 ggaaagtatt ttttccttca tcttccatcc ccctaaatcc gaacattata aataaagtcc
    23821 gttaaaattt cgatttatta ataaaacaac gtgttttatc atatactaaa acaaaacata
    23881 agtaaacaaa aaattcggat tttaagcaaa atccgaacgt tccatctgat taaatccctt
    23941 tatctcaaag ttcatgaaca ttcactttgg attacaagaa tttctttatt gtgttaataa
    24001 agtttcttca ttctagtctc aaaaatcaat agtgtgattt gattttacca tttcgtttct
    24061 gttcttcttt gatgaattct tttgtatcga caggattcag attatttagt ccgccaaaac
    24121 ctgtatcgac catttttccc cagccttttg tcttcttttt tcctgatttg agattctttg
    24181 ctcgaagctt ctcactatgt tttgctcgcc gatacttcaa ataaccttct aatcttccca
    24241 ttagatccac tgtttttcct cctttttatt caatcagacg actcagcttt tcctataaca
    24301 aaataattgc cttcagggtc agaaaaattg aaagtcaaga tgccattgtt atctgtgatt
    24361 tctcctggtt cttccatgtt ctcgtagata gtttcaaatt catccgtaaa aaatactaaa
    24421 gaaggcggtg gtcctaatac ctctggtgaa aacttctgca caaatacttt tgggaatacg
    24481 cctaattcta attcttttga gatgctgagt acaatactct taaattcttc tggcaattcg
    24541 attgtttcag aaatttctgc accaattttt tctacaaaga atcggcaaat catctctacg
    24601 tcattgacat aaagcatcac acgtgttttt tgtatcatca tttgaccctt ctttctattt
    24661 gattttcttt cctgtctata aactgattcc attatatcac gaaagcgcaa acaccttgtg
    24721 tttgatacta ttcaagaaaa ataaagcaat agtttctagg attgctttcc tccacaaact
    24781 ttttttacaa aaaaaaaacg gcaatgaatg ccgctcttct tatttcgatt cttttataat
    24841 tctgcttctg attcatcttt ggttagtgtg tgtctaacac tagttacgcc aaatgtttga
    24901 tcgatttttt ccttcaacgc ttcgattgcc tgtgcgccac gtgccgcttg ttcagcattg
    24961 atggattcaa tgaccagcac cgctgcttgt gtttcttccg tcagcatcgt tctttgggct
    25021 tcacgccagt tgagacagcg acagatcgct ccttgttcat catagtagat gatttcttcc
    25081 ggaagtgccg gagcatcgga atctgcacct aaaggcagga atgattcgcc accttgggct
    25141 tttcctaaat gcagatttcc tgcgatcttt tcgatatctt ctccgccgca aggtacgcca
    25201 aaagacaagg aaatactatt atagatatct acaagcggat tgattgggaa aaattcccgt
    25261 tcttgatttg cacgtttcag taaagcttca atagaagaac gtgcaccttt tttagtcttg
    25321 aatgtggtaa atgcctgacg ccactgagca atgacttcgt tttggctgaa tgtttcttct
    25381 gtaaggtaat ttcttgcttc ttttgctgcc tcattcaata attgatgata cgtttcttca
    25441 ctttcttttg ttacgtggtt atcgatacca tttacggata agatttcgat ggttgcttca
    25501 ggaaatactt cccagaaatt ggtatccact attacttttt tcatctgttc acacctcttg
    25561 attagaataa ttgcttgatg aatagatagt ctgtttgggg atcatctccc atataaaaaa
    25621 catgttcgct gtatttgata aatccttttt tacgataaaa agcgagcgca acatcgttgt
    25681 gttcccaaac accgagccaa atggctgttt tttgcttttc ttttgctttt tcaatagctg
    25741 tatctagtaa aaatgtaccg ataccttgat gtttaaattt ttttcgtaca tagattcgct
    25801 cgatttctaa aaaatgatca gccatttcct cagattgact cgttcctgta tttagtttca
    25861 ggtaacccgc aggctcttga tcgatactca ctaggaaaaa atcggtttct ttatctttta
    25921 gctcttctgt aagtttttct agtgcataag cttgtgtcaa gtaatcagct aaatgctccg
    25981 gtgaattatc ttttccaaat gtatctgtaa atgtttcgat actaatttgt tgtagtaagt
    26041 ctacatctga aggcgtcatt tttcgaattt cgtatttatt cacggcttct tcctttcaat
    26101 agatcctttt attgcctttt ttgacaaaat tccaatcttc gctaacattc ttgcatactt
    26161 tatttaaaag atattccaat tgttttgctt cttcgtcaga aagaccattt aatgcgactg
    26221 cattggagta gttgttttct cgaatgatga aaggatagat ttctgctcct tttttagtcg
    26281 gatagagttt cttgattttt ttattttctt tatcttccaa acgttcgatc atcccattgg
    26341 attctaattt cttgattgct cgggcagtcg ttgtacgatc tactttgatc atttctgcta
    26401 gtttttcttg gatgattcca ggattttcgc aaatacgtac taaataaaga tactgtcctc
    26461 ttgttaaatc gacttctttg aattcgatat tgctaataga atctagcgct cgggcaatca
    26521 ttccgatgtc tcgaaggatt tcagccattt catcccacct ttattttgtt tgtaagacta
    26581 gttcacctct ttttgttgca aatgcaacta ttttcaataa aaaaatcaag ttctttttta
    26641 ataactagta aagtatattc ttttcttctt ttacgaaaaa gctcaatcac aatagatctg
    26701 gtttttgttt tctaaaataa gtaactgttt cttcgttgtt cgcttttctg atagctttgg
    26761 caactcttct atactaaaaa atcccatgtt ggaagtttca ttattctcaa taaacttggc
    26821 ctcttcaccg tggatcgcac aagcaaaaac aagtttataa tactgaaaaa gctgtggaat
    26881 atctttttgt ttattcgtat caaaaactgc tcgcaactga gtagtttcta ctgttaatcc
    26941 tgtttcttca tagacttctt tacgcacatt ttcttcagga gacaatccta tttcagcaaa
    27001 tccaccagga agtgaccatt ctttcgtccg tttatcttcg attagtagga ccttgccatc
    27061 ttttttgata taggcacgaa catctacttt tggtgttgga tgtccttctc caatcgttgt
    27121 gagcgctttt atttcttcga aagtttcttt tcctatttca ctgatcagtt ccaatgaaat
    27181 cgtccggatc tcctcaaaac gctctttatc aaatacatct tttccataat atagaccagc
    27241 ttgagaaagt gcgagtagtc ttttgtattg agccaacttc ttgttcattc tcttcccttc
    27301 ttttttagca aatgtatgac tatgtaatca agtatagaag actggtttaa ttacggcaaa
    27361 taaatataat gaaatctgca ataaataaaa gaatgttaaa aaactcgaga acaaaagaca
    27421 ttcgacttct ctggggctgt gaataaatgg cgttcaaaag cttgcatctg cggtaataag
    27481 ccccaccaaa cgaaaaatat gacgagctat tcttgtctgg ctgttcttat taattgaggc
    27541 aggacagctt tttcacaacc tccccactaa acggtgttct cctaccaact cctcggtcac
    27601 aagtcacaat attcatcaaa catgagaagc tgtttttttg aaattgctcc ttgtgactcg
    27661 gagctgaacg acaggctcac gacctctcgg taaacagcgt tcaaaagcca atttttcgat
    27721 attaagccat ttctttgtta cttattgtca ttgatttctt tttctaattt atccaatagt
    27781 ggagtgtaat ccacttgagt atagtctgtt acatcaaatt catatagtgt tcctaactgg
    27841 aatttgtcat attttcggtc ggcgatgatc tttttgaatg cttctttcgt aatatgattg
    27901 gtccctttcg ttcgatcttc caatacgtca ccatagtgat aatgatccat gatatagctc
    27961 aaatgacgat ctgattcacg atcacgtttg taccgacgtt gccataacac ttcaaagtct
    28021 gctgttaggc gaatcgtgat cacctgatat ccgtatctat ctgctaattc ttggagtcgt
    28081 gctttttgct tatcactaaa aggatactcg gacacaatca ctttctttcc tgcttccata
    28141 tacaaatcaa gtgctttgta atagaaagga taaactttcg tcctttcttg ttccgcccgt
    28201 tcttccaaat tgttaaaccc gatggattct gcatagtatt ccttgatttc atcgagcgtg
    28261 atggcataca tatctggaaa tcgttcccgt agtttattca taagatatgt ttttcctgta
    28321 ccaggactac cagccagaag aatgaaatac tttttcatct catttatttc ctaagttaat
    28381 tggactttcc aagttcataa acagtccaat cttatgcttg acaatttctt ttactgcttc
    28441 atttgctgga atcacattat ggcgaagaga cttgttgatt tctgtttcac taaaggtttc
    28501 tttagctact ttcgtccagt tgactaaaag ctccgttcca acattgaatt tgcggatccc
    28561 gttattgatc aattcaggat aatcttcttc tttcacacct gttcctccat ggataactag
    28621 ggggacatca actactgcat cgatttcttt cagcaaggga atgtttactt ctgtttttga
    28681 tttgaattgt ccatgattcg taccgatagc aatagctaat gcatccacgc ctgtagcttc
    28741 tacaaatttc actgcgtctt ccggtcttgt atataccttg tcattttcag cgacatggat
    28801 tccttcttct gtaccgccga ttgttccaag ttctccttct acggaaacac cgtgcgcatg
    28861 ggcatattct actactgctt ttgtcttcag gatattttct ttgaaaggca gatgggaccc
    28921 atcatacatg acagaagtat atccgctgtc gattgcttct ttgatatcat caaagtctcg
    28981 ggcgtggtct aagtgcaaga ctgcatcaac catttcttct tctgcaatag ctgtcattac
    29041 attgactaac acatgcatgc cgatatattt agcggtatcg acacttgttt gaataatgat
    29101 cggcgaaccc atttcttttg ctgcgcctag catagcagga agcatttcta ggttatgcgt
    29161 attaaaagct ccaactgtaa agttcaactc ttctgctgtt tttgttactt ctttcaatgt
    29221 tgtatacatc ttttattgcc accttatctt tttatttgtt tcctttgatc gttacttgtt
    29281 ttgcaatttg tcgcatctca tccattttgc ccatgtagta atcgatccct tgatcatcac
    29341 cagcacgagc agcatctgca cgcttctggt tatagaggct catcagtttt ttatacccat
    29401 ctccgatcgt ctgtttattt tccaaactct tttctaaata ttggatggct tgatcgttca
    29461 catacaattc agaaaattta agtccaactt gttcataaag tttcgctaat ttatgcttat
    29521 cttgggtagt ggaaatctct tgtttcaatt gtgtaatctc tgattgaatc ttttcggtcg
    29581 cttctggcga tagggctttt tcttcttttg ccagaacttt tttcggttct ttttcttttt
    29641 tcttaaaaaa tccaaacatc attttcccta ctttcaatta aaatgctttc aaaactgggc
    29701 ttaagatcca ggcatataag agtgctgcgg ctactgtatc tacatcggtt gctgtagcat
    29761 tgttgaatcc catcgaatta aagatcgtta ctagcaaagc gggcaataat gtaataaaga
    29821 aaccatgagc aataccgcca atgatcgctc ctcggcgtcc gccaactgcg ttgccaaata
    29881 tccctgctgt ccctccggca aagaaattgg ttagcatacc aggtaaaatc atcgctaagc
    29941 cgaacatggg caaagtaaac atggcaataa tcgtaccaat cgttgtcgta atgaaaccta
    30001 aaatgacagc atttgggcta taaggaaaga aaactggaca atctaaggca gggatcgcat
    30061 caggaactaa tttcatagct atccctcgaa atgccggcac gatttcacct aacagtagac
    30121 gtacaccagc tagcaataca tacacaccca ctacgaattg gatggcttgt aaaaaggcaa
    30181 acatgatata gttttgatct cctgataatt cagaagcgaa tggttcgcct gcaaataaaa
    30241 cagtgatgat atatagcggg accatcacga ccatgacaga caaataagta tcttgcagaa
    30301 attcgaaatg tgtcggcaac ttgatatctt cgatcgactt tttattttcg cctttctcac
    30361 caaaaagctt agcaacaccg gcttcaaata agtacccgat cgtacaaaaa tgacctaaag
    30421 caatatcatt tgatccagtg attttacgaa tgatcggttg cgctactgcc ggcatagcaa
    30481 tggcgaaaca agctccgata aaaccaccga ccaagatcaa tacgatccct cgcagaccgg
    30541 caaaatagcc aaagactgtc gtcatcgttg ccatccataa aattgcttga ccagttaaaa
    30601 aaatgtactt ccattttgtg aaacgagcca aaataatatt gaatacaaaa atggctaaga
    30661 acgtcagtgc aatatctcta cctaaaccca aatcattcat tgcttgacca ttgatagatt
    30721 caatagaagg gatgatccct tgcatatgaa atccttcagt aaagattttc ccgaaataag
    30781 ttaaacttcc aacgatgatg ctcgaaccgg cactcaacac ttgaaatcct aggagtgtct
    30841 ttaacgtgcc agagatgact tgtcctgctg atttcttctg cagtagtaga cccaacatag
    30901 caatcaatgc aatggtgatc gatgcctgag tcaaaatatt ttcgatgata aaattgataa
    30961 cgcccatgtt tttaccctct tttctttttg tatttagata actcccttat cttgcagaac
    31021 tggggtgatt ttttcttcaa tttcattttt tgaaacaata tttttcaaat agatcatcgc
    31081 cgttttagga tcaactgcga acttttcgaa ctgcgaacga aaattttctg ctgtgatgat
    31141 cacatctggt ttcatggaaa ctgcggaaga aatatcacaa tggtccagtt tggcttctac
    31201 tcctaatttg ttcaaaacat cctcagcaga catctgtgct gcaaaactac ttcctaaacc
    31261 tgcaccgcat acgaataaaa tgttcaattt gttcatcttt gttctccccc gtatcattta
    31321 ttatttctca actactgaaa aaagcagttg tttgaaatct tcgatatttg tgcattcaat
    31381 caatcgatcc aacttctctt cgttgttgat caattcaatt agttctttca tgatgttcag
    31441 atgcgagtag gagtctactg ctgccaaaca aaaaataatc tttactggat ccatttcagg
    31501 attaccgaaa tcgattggtt gctcaatcgt agctacgctg actcctaatt tattgacccc
    31561 atcttctggt cgggcatggg ctagtgccat gtgtttgcca atcacgatat acggtccgta
    31621 atcattcact gcacgaatca tcgcttcgac atagcgctct tcgacaatgt tttctttaac
    31681 caatggtcta gcagctagtt caatcgattc ctcccaagta gtggcttttt ctttgatcat
    31741 gatattgctg tccgtcaaaa tatcttttaa cataggctgg atctcccttt tgttgatttc
    31801 taaattgttt gtttcgaata atttttctaa cttgccatag atgattcgat ctactcggcc
    31861 accactttct ttcatgacat ctattatttg agtgaataac tccgtcgatt catgactgtt
    31921 aggctctaac cgctgtagtt cttcatttct tttcaaaaag tcttctataa ccaagatatt
    31981 cgtctcagtt aaaatcggat cgacaactaa aagcggctta tttcgataat tcaattgaaa
    32041 ggtgctgaaa accagattga catccaattt atctactaat tcgatttctt ttgaacttaa
    32101 aactgcagta atctcgatct gaggaaactt ttctttcaga ttctctgcta acagatttcc
    32161 agtagccatc ccatggttac agacaacgac tgatttataa acataattca agtctcgctt
    32221 gattacactg gcgatcgtcg aaaagtggat gacaagaaaa gctatctcgt cctccagtat
    32281 cttgccacca attacttctt cgatcgtagg aacaaaatga gtgactgcgc ggtagattgg
    32341 gaaataattt gttcggatgt tttctttcaa tggattcatg acttggatat gattcttgat
    32401 tcttacaatc agtgcagcca tgtgcttata gagattttcg aataaagctt cttcctttag
    32461 atggaaaggt acgtgtgtct cgttctctac aaattggatc aattggatcg ttagtaattg
    32521 agcttgtacc cactcgattg aattggagat atctctagca ttgaacgtct caatagtgaa
    32581 acgaagataa tttctttcta cttgcgggac attgtccaat tgaaattcct cgatcatgtg
    32641 gtcaataaat gcagaaaagc tactgtcttt tatttctgta tttttccaat taatggcaga
    32701 gataaattca tgtttcctga ttcgctggat ccagatcaat gtaaaaagca ggatttgttt
    32761 tttataaata tcatcttctt gtttcaacaa cttattggaa tagatctcct gtattttttt
    32821 gatttccacc aaaggaaaat aatggagaaa gattttttga gccggtgtta attgtgcatc
    32881 ttgattcata aagaagtcgg tcattcccag attctgattg ataaaatcat agatcatcgt
    32941 acggatagat cgttctgaac ctttataaac cagtccttgc tttccataac tgacgatctc
    33001 tatcccataa ctgaccagtg ttgctcgtaa ccgtctcata tcttcatcta atgtactttt
    33061 agagatttga aattcttctt cttttttgtt tagatggatc gggattcggc tgtaagcaac
    33121 ggctaaaact agatcaaaaa tacgttcgcg ccgattcaaa aagccgtctt tcacatcttt
    33181 tatttcagtt tctaatcgag cttgcttttc cttttccagc ttcaacaaaa aaactttgtt
    33241 gcgaattgta cggatctccg gaagcttttt actgctcaac cagatattcg cttcaagaac
    33301 ttcctgacgg atcgtccgct gactgacatt gaactcactt gctagatgtt ttgcttttac
    33361 tggatattgg gctgtcatga ttctgtgaag tatttcaatt gttcttgttt tcatagaaat
    33421 gatctccttc tgatttcaag tatatggttc cgcttacata ataaaaagta gatatttctg
    33481 ccacttgaag tggaaagaaa gtaagcaaag caaacaaaaa ataagccata tgctttttca
    33541 tctcctcaac gaaaaagaca tacgcctatt attacaaaaa ttttgcccat ctatacaaaa
    33601 aagaggttgt gaaaaagctg tcctgcatca agtaataaga acaactaaac taaaatagtg
    33661 cttcctattt ttcgtttggt tgttcttatt atcgcagatg caagctttta aacaccattt
    33721 agtggagagg ttgtgacaga gatgttcagc cttgagcgat aagaagcgat tttgaaaaat
    33781 cgcttcccat attttacaaa atcgtgcctt attgccgata ggctatctct ggcacaccgt
    33841 ttattcagaa aaaggagctg cgacaaggct tttgtcacaa ctccgttcat aaatatttcc
    33901 tgtcaatcca gcataatcgg ctgaataaaa tcggcttgcc atcttttttc tttctcagaa
    33961 aaatcaaaat accatatctg agaaaaatac tgtcgttgtg tcttacttcc tgagatcaat
    34021 cgcccatctt ttcgatcgac tgaataatca cagcatctga aatcaattcg gatggcaaaa
    34081 ctattttcgt ggatctgtcg ataatttcct acttcctgaa tagttatttt tttagtatga
    34141 tttcttacac cgtctgcttt gtttttttgc agaactttct gatgttcggc aaacagcttg
    34201 tctgtataac agcttctggc tttttcagga gtttcttctt cccaagcgga ttggatcttc
    34261 atgaatatct tttggatttc cagaaactgt gctttctttt ctttagccgt tcctgacatg
    34321 cgggacaata tctccgcttt cagccttttc ttttgtcttt tattcttgac gatagaaaaa
    34381 gcagaaaccc ctcctactga caaaacagct aatgcaagaa atcccgtttg ctcataacta
    34441 gaaggacctg tacctggacc ataataccca taagaatctc tgccgtaaga acgactgcca
    34501 aaataactgc ccccatatga acgaccacca aatgaacctc tgcccgaact tcgaccgcta
    34561 gatgtacctc caccatgacc acccgcgaca gcgaatcctt gggtcggcag agcaaacaaa
    34621 cataggccca ctaacaaaat gattgctaaa taattgattt ttttcattgt cttcctcgtt
    34681 atcttttatt acaaaaaact atttttatga tagccttgct aaaaggaaga gtcaataacc
    34741 agatgcataa actgtttttt tagcaatttt gtcttattta gtcattgagt aacatcggac
    34801 aaatgtatgt gtcggcagtc cataattcct ctatcttcag catgaacaag cttgcagaca
    34861 agagatctgc gcttcctcca ggagagattt ggttttcctg acaaaagtgc aacagtgctg
    34921 taaatggacg atttggtaaa gcactttgac tagcagcatg agcaagtttt tgcatttcca
    34981 ctaacgtttt ctgatcactg cgatgcaata cgcatgtgtc atctagcgaa ctcatcaaaa
    35041 ctaacaacat atgcatttgt ttctgtacat atgaatcatt atctagctcc ttagctgctt
    35101 gaattgcaag cctgatatgc ggatacccta atatcgcttc ttcatatgca ccatttacgc
    35161 catatttttg cttcacccta tgaccatgag tggttttttt atgacgatat tttgtatcag
    35221 gaaaagcagc aagcttgctg acatcatcaa gtattttcga taaagaaaaa ggctgttcca
    35281 tactgatttt ttgtgcaatg acactgatca atagccccat tgcccaaatc gctcctttat
    35341 gggtattgat gccatttgta gcaatcagca ttgccttttc cgcttttcgc ccaatctcag
    35401 caattctttc tcttaactcc tgatcaatag catgatgcca tgctatttga gccatttctt
    35461 caaaaaaagg agttagcgtc ttagcagact taagaaataa agcatagtcc atatcggaat
    35521 gtgcacccgc atccagtgca tccactaatc caggttttgg acttaatgtt acttctgcga
    35581 tcaatgcttc ctctaccaac gcagcgagtt gctgagtcac tgcttttttt cgttcgtcat
    35641 ttatcatgac actcactcct tcttcctact attacttgct gaaacctttt ttgatagcta
    35701 cccaaatgat atgaagtaac cagcttaaag caaatgcaca acttgccgtc attagataag
    35761 ctacaagaat catgactcct gaaggtaact gcagccaact atctttaaac aataataaca
    35821 gtacttggaa aacaaataca ttggctaaat acgtacgata agcataaaca gacaaccatt
    35881 tgaacaatgg caattttggc gaatcgttta caatcatttt ggaagcgcct atgaagacag
    35941 caaagatgat gactaaactg tataaacttt ggatcgtatt caagtaaggt gcattcgcaa
    36001 agctcaagtc tcctggatgt gcgagcaatg aacggacaga aaagaacgcg ataactaagg
    36061 caacaggtaa gaaaagataa cgtactctgt ccaaatattg atagactttt tcgtgataaa
    36121 caaatgcggc taccccataa atcatgaaac tagcaacaaa ccgatctaat aagtaccagc
    36181 tgtcatgata aggcccagtc aatacttgtg tttgatagaa cagataccat gcgacatata
    36241 aaatcgttga accaatcaat actggccata catatttttt attagcaaat actttgtaac
    36301 cgagccaaac aaaaaacggc atgaacaatt ggatctgcag catcataacg gtataccata
    36361 aatgaggcgc tccatcacct gtgacatatt tcagtaaaaa gcttgcagta tccgtatacg
    36421 gagtttgttg ttggactgct ggaaatagcc aaagataagc cgtcgtccat agaagatacg
    36481 gaacgactag ttcaaaaaac ttttctttca aaaattccca ataagacaaa tgctgacttg
    36541 tttttaccat attataaaca attgcaaaaa taaacattgg tgctgtgtat ttaacgatga
    36601 cgtaaaaggt accaagaaaa gctgtatttg ttgcgctgtg gctgtttgcc aaagcaaagc
    36661 tcaatatcgt ttgcatcata acagccgtta cagctgatac tttctggaag tcacttacgt
    36721 tgattttgat ttttttgttt tcaaacatct ctttctctct ctttttcttt attaccaaag
    36781 ttctttggtt aatttaggtc cttcgactgt tttcaataga atttttttct ctggctctct
    36841 caaatactct tttagtgaaa aaccgccttg ccgagtcact acttgggtat cgaattgctc
    36901 aaaaaaagca ggatgcgatt gaattacctg aattggcaat tcaatcggtg aatttgcgta
    36961 cagcagcaaa tcaaaatcac tggtttcttt tactgccgga atcccagtcg ataattcaaa
    37021 tcctaagctg ccgccgattc cccatttaca tcctgataat atgtttctag cagcatgaaa
    37081 ttgctgataa acaggataat ccatgatttt ctcttgtcta tacgattctt gttcgatgat
    37141 gtcccacgga tgaatgactt gtttgacggc atgttttgag atttctgttg accatctctg
    37201 attgcgggca ggtccacgta aaccaatcgg tagtatttct gcgtgatccg tcgacgcacg
    37261 acgaactgtt ccgaacatct tttcagttag aacgacccat tcaggcaagg tgaacccttc
    37321 tatttcatgt ttatcaaaaa ggacaatatc atgtgcttga atcatttttt atgcatccca
    37381 ttcttcgtcc attttggcac ggactttatt tgtttcgaca cgtccgaatg ttttggctgt
    37441 ttcgtttgtg tatcgatttg tcagcatcgt gtcatttgta ttgcggacat cttgaatggc
    37501 ttcattgatt gcttcgatga ctttgctgac attttgttct gaagcagctt ggtcggtgat
    37561 atcttctagg aaatgataga tcgctcctag ttttgtataa ttattgatat cgtaagcgat
    37621 agctggaact ttttcagcag ctgcttcgat ttcagcaacc gaacgttttg tcacacgtgc
    37681 agcactttct ttagacatcg cttggacggt aatttcttta ttgtttaaag caatcaagcg
    37741 gcttgattgt aatccatgtg ctaaaaatgc acctgaaata gcatttcctg caatcaatcc
    37801 aataactgga tgtccagctt gacggagttt tgcataagca gcagcactat tagccaaagc
    37861 cacatggata ccgatcaatt cttcgttata gccgtatgct tggcttggta catcgatcac
    37921 aacgatgatt ggccgtttca cttttttgtc tttatcttct tcgtaaacgt gatccaaaat
    37981 ttgtcccatg cggaaacctt caactaaacc aacttcaccg tttcgtacac ggtacatcgg
    38041 gtttttagga tcaggtacga ttgatgtcac gatggcttct tctatgaatt tacttgattt
    38101 accataatac acagtactaa tagaagaagt tggatttttc atgccagtta gtgccgcaaa
    38161 ccaatcgtaa ccaacacttg ctgcagctgg ttcatttcct tctgctactt ctggtaagtc
    38221 aattgatttt gcttgatggt tagcaattgc ttcattgtaa tcgtcaatgg ccattggttt
    38281 tgaaagatct aaagaatcaa gtaatgataa ataaaatgct gagctttcac tgcgatgcgt
    38341 gtcttttcgt tcgtccattg ctgcgatgac agcagctttg attgcttcta cactatcagt
    38401 cactaattca tcaatgattt ttgattctac ccgttgacga gatcctaatg tattccaaat
    38461 caagtctttg tcactagaat caaattctcg aacgcctgct tcttgttcaa taacttctgg
    38521 tccattcaaa ccgactctcg ctttttttgt tgcgattaaa taactcatta atgctgaagt
    38581 aatcgacata ccgccaaatg atcctacacg tcctggaatc aaaccgatga ctggtacata
    38641 ttgttttaga gcaatgatta catttccgat ttctgaaata gataacagtc cgtagtttgc
    38701 ttcttgcaaa cgaacaccac ctgtatctag tacaatgact ggaaagatct catttccttt
    38761 tttattttct tctaacacat gttcaagtgc agcaacgatt tttgcaccgg aaacttcacc
    38821 gataccgcca ccttggaatt ttccttccat agcgattact actgcttgtt tgccattgat
    38881 cgtgccacgg ctgacaacga tcccgtcatc actttcaggg acgattcctt gtgctggtaa
    38941 acttggcgcg atgatttgat cgaatggatc aatcaattca cgtccattgt caagtagagc
    39001 gttcactcgt tctctggcgt ttaattctac aaaactattt ttcatctgaa agttcctcca
    39061 ttgcttgcgt caatcgtagg tacacaactc ctggtgtagc accgaagtca ttgatcacga
    39121 tatctgctga aattggataa cgatcaaaaa atctcgttaa tacattgttc catacttcgc
    39181 cgaagccatc gcttcctgta caaattttta cagtagattc tgttttttct gttggaaaca
    39241 tcaagatttc caaatctcct gaaccgacca ctcctacatg gattttctta ttgatcggct
    39301 gtttcgttgg atatttataa gctaattgtt ccatggatct ctcccctttt tgtaaaacag
    39361 agcatacacg ttctgcttat tcgtctttct tcttccatct gggtaaatgg cgacaaaagg
    39421 tttttctcgc caattttatg accaagttct gaatttcatt ggtggttcat acaggccatc
    39481 tgaccattcg atcaaatcat cgatggtttg tgcagctaat aatgaacgtt tcgcttcact
    39541 acgtttgatg cctagatctt ctggtaattt cacgatgccg gctgcacgca agctatctag
    39601 tgattctttc gtgctagtca ttccaagagg tgtaacaccg ccaattgctg caattgctgc
    39661 ttgtcgttct tcttttgttt ttgctttgta caaataagca attccttctt ctgtcacgat
    39721 atgtgtagta tcttcgctat aaatcatcac tggtgcattg gctaagcctg cttgtttttg
    39781 aacagctagt gcatctaatt cttcgacaaa gactggtttt ttatttgaac catatgtttc
    39841 aaccatttga acaactaatt tttggccttt ccctaatgga tcatcattgt cgcgaagtga
    39901 ttgccatgct ggtgtagaat gacgacgacc gccaggatta tgtcccatgt taggcgcacc
    39961 gccaaaacca gataaacgtc cttttgttac ggtagaagag tttccttcgt aatctaattg
    40021 caaggttgaa ccgataaaca tatcgatggc atattgtcct gcagcttgtg ataatgttcg
    40081 gttactgcgc atcgtgccgt ctttaccgac aaaaaagaca tctgggcgag cagcaatata
    40141 tttttccata ccaacttcgc caccaaaact atggatgctt tcaacccaac ctgattcgat
    40201 ggctggaatc atcgttggat gtgggttcaa tacccagttc ttcgcgattt tcccttttaa
    40261 ccctagtgat tcaccataag ttggcagtaa caattcgata gctgctgtat tgaatccaat
    40321 accgtgattc aaagattgta cgccgtgttc tgcgtagatt cctttgattg ccatcattgc
    40381 cattagaatt tgcaattctg tgatgttttg aggatctcgt gtgaataaag cttctaattg
    40441 ataaggttta tctgctttca cgacaacgtc tacccagtca ccagggatat ctacacgtgg
    40501 taaagaatcg acaacttcgt taacttgaac gatcacgata ccatctttga aagctgcagc
    40561 ttcgatgatt gttggtgttt cttccgtatt gaaacctgtg tacaagttgc cgtctttatc
    40621 tgctttatct gcagctacta aaacaacatt tggaatcaaa tcgatgaata agcgtccata
    40681 aagttccaaa taagtatgga tatcacctaa tttcattgtg ccgtcttcaa tcatttgggc
    40741 gacacgcaag ctttgtgcac cagcataaga gaaatcgatc ttgcttgcga ttcctttttc
    40801 aaaaatattc aaatgttctg gtcgtgagat actagacatg atcaaatgca gatcattcac
    40861 tttttctgca tctacttttt caagactttc tgaaagaaaa cttgcttgtt tttgattgtc
    40921 gccttctaat acaactttgt cgccgggagc aatcagtttt tccattactt ctacgatttt
    40981 ttcagtttct acatacttgc cattgagcaa gttgctgatt ttttccaatc gctgcgcttt
    41041 tttttcgcgt ttagaagccc agttgcggtt tggtttttcc ataattagtc atctccattt
    41101 ttgatataga aacgtggcgt catcaatacc atgttggtct agattgatcg tacggatccc
    41161 tttatctaca ccaaattttg tatgaatcag ctttgtcaaa gtattgccgg ggggaaattc
    41221 aatcgtcaga tccattccta attcttttgc caagtccatc atttggttcc actgcacagg
    41281 gaaagctagg ttttccaaca aatctttacg aatctcttct gcgtcctgag tggctcttcc
    41341 atccgtattt tttatataca aacatctagc atcagataga tggacagact gcatatacgg
    41401 cttgaatttc ttgaccgtat cattcatcaa gagacagtga gatggcacag ggactttcag
    41461 cagcttcgct gtttgcgctt ggtgccgttt ggcttctgcc aacgtaacgg ataaaccttc
    41521 gatactccca gataacgtat gttgcatcgg acaattttca tttgacagat aaactggatg
    41581 gtcaggatca aatgtttttg ctacaatttc ctcagcttcg cttctcgtca cacctactac
    41641 tacgcccatt gcataaccgc ttggataagc ttctttcatt aagactgcgc ggtgatagac
    41701 tagttccgct gcattctcaa atctcaaaga tcgacaagca acagctgcac aaaaagcacc
    41761 aatcgaatgt cctgctgcaa tatcaggctg aataccgttt ttttccattt catctaaata
    41821 aaatactgct tttgtcagta atgctagctg gataaaaacc gtatcttgat agttttcttc
    41881 tttatcaact aaccgatacc ccgtcacatt ttctaaacgt tccatgtaca tttcagggat
    41941 atccgctaac atccctaact tctgactgcc ttgtccagga aataagaaac ctgtactcat
    42001 gagcctcgcc tcctcagcac ttactttttc cactgctatc ttagtcaatt tctgctataa
    42061 taaaaaatgc caaaaaaaga aaaaaccata acaaaaaggt atggatggga tggataatta
    42121 tgaaattgct tcatctgcag tattttaaaa aagtattcga aacaaaaaat gttacccaag
    42181 cagccaaaga attatttatt tctcaacctg ccttgagccg tgcgatcaaa catttggaaa
    42241 acgaattagg tgtccctttg ttttaccata gcggcagaaa cattgagacg accgtttatg
    42301 cagaagaatt ttatccatat gcagtcaaga cattagacac attagaagaa ggaatcaaat
    42361 tattgtcttc ggtcaatgag aagatcgtta cttccgtcat attgtattta gaggtagcct
    42421 ctgtttctat tccgaacttg gtccgaattt ttatggaaaa gcatcctgat atccaattaa
    42481 cgatcatgca acatcattta ccagatgata ttaccgatcc tgtactgtac atcacttcgg
    42541 agatgaagcc tggcatgacc aatattccta tcatgaaaga acctgtttat gtcgccattc
    42601 ctaagaaaca tcctcttgct aaaaaagaac atctgcaatt agaagatatc caacgcaccc
    42661 ccatcttgat gctgtcaaag agcaacgcct tccgtcatac actggatgca gcacttgaag
    42721 cgaaaagtat cgaattgacg atcagttcga cgacagatga tcctgcgaca ttacgttcta
    42781 ttgtcaagca aggattagct gttagctttt tcccaaaagt ttcttggtct tacgataaaa
    42841 atgatccttt cgtcttgcgg gaaatcaaag atttgccctt gacacgaaca atttatttat
    42901 cttctagctt cacagaagat catcctttga tcaaaatgat tgcaaaaacg atgcgggaat
    42961 tttatttagg aaaataaaaa aaaaagagct gggacaaaat tcttgtcgca gctctttttt
    43021 cgaacaaacg gtgttccaga agtaatttct tagaaaataa gccgaaattt cccaaaaatt
    43081 tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctaaacattt ctgtcacaac
    43141 ctcttctcta ttgtcctaga cattcattgc gttgatttaa aacttccatc aatcaaatct
    43201 gctagttcat ctagcttttc tattttacgt agatcaatag agatccaatg ttctttattc
    43261 atgtgatagg ctggaaaata cccctctttt cctcgcaaaa ttccgccaag ttcaggatcg
    43321 accttcaaat caagaatatt gatgatccta tggtcacttg catcatcata gattttttct
    43381 tctggaacag acatcaggac cccaaaccat tttttgcttt tttgatgtct gaatacgcaa
    43441 taatcaggaa attttttaaa aatatattct ggagacaaat tgtatgtttc attgatgtga
    43501 tcgattagtt cttttttcgt tagcatctgc ttccatctct ttcttattga ttcgctttat
    43561 tcaaagatac cacgtaagaa tagaaaaatg aatacaagta gttgctaatc aaatacttcg
    43621 atatttttct tttttatcaa ctcttaaatg ttcaatccgc ctgtgttggt cttgctacca
    43681 tctactatta aaatgtttat tattgtttgc ccacctattt tttgatttta gtggtatcat
    43741 ttttcaagtt catgatgaaa ttcttatcat cagtaaatgc tccagaaaaa taaacaatga
    43801 ttgaaaaatc agttgaaact tgaccaccgt ttattttctc cgtattctta gaatagaagg
    43861 gagtctgatt gatgtattca ctaatgaaaa aaatcattac cgaaaaagat attcgacgtc
    43921 atgtttcttt agtagaacaa ttgctgaatc atacaaagat aaccgtaaat gaattagctg
    43981 aaatcatagg gacaaccgaa cgaacgattt tttctgacct tcaatctatt cgctctcagc
    44041 tgcccgaagg ctgggacatc atcagcgatc aagcaggaat cagtttgcaa aaccagcaaa
    44101 atttattaac aaatgacctt tgggagattt ttttcaaaca atcagtcagt gtcgaactgc
    44161 tgaaaaatct gctttttaca aaaaaagttg ctgtccctga ttttctagcc gaccatgggc
    44221 tttcttatgg gacattgaaa agacatgtga ctaaaatcaa tcagcgttta gcaagttacg
    44281 acttgcagat cgatttgacg aaatatacag cttgtattct tggaaaagag cgtgcgattc
    44341 gtacttttta tcatcgattg ctgattcctt tcactcataa caactatttt ttcgaggatt
    44401 attcgatcca tgaatcccat tattttcaat ttttaagaaa cctcagtcaa actgaactag
    44461 cggttgaaac agaagagatt ttcggaacat gttggttctt tatcaatacg atccgtataa
    44521 aagcgaattg ccgattagat tcttctatcc ataccaacag cacactctcc tccctgtatg
    44581 actctgcatt gaaaaaattg tatttaacgg aaggtattta tcttaaagac actgagcttt
    44641 cttttgcttc tttctgcttt ctggaaagtt ggaattacaa caataactat ggacaagaaa
    44701 ccgctcgctg cctgcatcat tctccatttt tagaggtcct cgaaacgttt gtagaggaac
    44761 tagcttcaga gctgtctctt gatcaactaa aaaaaacatc tctgactgat aacttggctc
    44821 tcctcatatt aaaatatcat gaatcgccga tattgattga agcattggac cgtcaatacc
    44881 atcgtttttt agaaacatat gatcagcaat atgcacactt gtatcaacag aaagagaatt
    44941 tactgaacga tctaaaaaaa gaaatagaaa tcaatgaacc aaattacttt ctccaactct
    45001 tgtctctact gatccaacaa acgatttttt ctatcaaacc gaatttgttc aatgtctatt
    45061 ttattttcca aggagaacct tcatggaagg cgttcttgca gcaggaatta aaagattact
    45121 taggaaaacg tgtctgcttc ttacctatcg aactaaccga tctttccact atttcttttg
    45181 aaaaaacaga tatcttgatt tccaatttcc ctctagattc tctagatatc cctattgtat
    45241 acatttcttc tattccaacg aaaaatgagc tcaatcgttt gactgaactc actttcaaaa
    45301 cttttttata gtaacggcta gcgactgtat tctctagctg ttttttcttt tttgcgaaac
    45361 agtttgttca tgatcccttt ttctatttct acaactaaga atagaagaat cacatttgct
    45421 ccaatcaata actgttgtgt catcgttaaa cttactgtac cgatcagctg ctggccgact
    45481 ggtagaaaaa taaccatccc ttgcaataaa gcaaggatac ctaatgaaag aaaaagcgct
    45541 ttgttttgca aaagaccttg gttcaatgac ggcttggaca actctctgca attgatcatg
    45601 taaacagctt gagctaagac gatattttgc agaagaatgg tttgctgtaa gctttgccct
    45661 tcaaactgca tagccaataa ataggcagga accatgatca gtagggagac atagatgatc
    45721 cgaaacaaat gataaccaga taggattcct tgctttggat ctcttggtgg gcgcttcatg
    45781 atttctggat ctggcgactc gaaccctagt gcataagata aagtgattgt cgttaccata
    45841 ttgacccata aaatctgtac tggggacaaa ggtagcgggc gattcagcat aagtgcccaa
    45901 atcaagatca atccttgagc taatgcagtt ggcaagaaga aattgatggt tttttgcaaa
    45961 ttatccaaaa tccgccggcc ctcttttacg gcttttgcaa tcgtatggaa attatcatct
    46021 cctaaaacca tatcagctgc ctgtttgctt acttcactac ctttgattcc catagcaatt
    46081 cctacatcgg atcttttcaa agcaggtgca tcatttacgc cgtctccggt cattccgacg
    46141 atttctccat ttttctgcaa agctttaaca attcgcagtt tatgttctgg tgtcgttcga
    46201 gcaaagacat cgactattgg cacttgctga atcaactctt catcagacat aagatccaaa
    46261 tcgatccctt ctaaaacttt ggcagtatgt tttaagccaa tttgttccgc aatcgctttt
    46321 gctgtgtctt tgtgatcccc tgtaatcatt ttcactgaga tccctgcttg ttggcattcc
    46381 tttacagctt tgactgcact ttcttttggc ggatcgatca atccggcgat ccctgcaaaa
    46441 gttaattggg ttaaagtctc atgcgtgagt tcctgtttcg aatctacttt tttataagca
    46501 aatcctaaaa cacgctgacc ttttctcgca aattctgcag ctgtctgact ccatgcttct
    46561 tgttctgcag aagaaagagt tgatttagca aataatactt ctggtgcacc tttgacgtaa
    46621 atcaccgctc ctttttcctc cgcatgcatc gttgccatat atttgtattc agaactgaac
    46681 ggaatctttg cttctatttt tttcaaaggt agattggctg tttctgtgtg tcgaatcagc
    46741 gcaacttctg tcggattgcc acttaaattt tctgttttct gttcttcttt tgtttttaat
    46801 tcctgacagt ttttcataat ggacaacacg caggcttctt cttttgcagc tacatccaca
    46861 actgtcattt cattttttgt caatgttcct gtcttatctg aacagatcac tgtcatagaa
    46921 cctaatgttt ctaccgaagg aagtcctttg atgatcgcct tttcttttgc catttcatgt
    46981 actccaacgg atagaatcat ggtcaaaaca gctggcaatc cttcgggtac cattgacacc
    47041 accaaagcaa tcgtagccga aagaagaata tgccaatcca taccatatcg aaatgtcgta
    47101 aaaataacta agaataggct caaacaaaga atgccttgaa aaatttgttt gtttaatcgg
    47161 ttgatttttt taatcagagg cgtcgtttgt tgttcgaccg attgcaatgc ttgattgatt
    47221 ttaccgattt ctgtcgtgtt tcctgtttct acaacgacac cgactgcaga accagattgt
    47281 acaagcgttc ctgaaaaacc catatttttc tggtcgccga tcgattcttc ttctgtcaaa
    47341 acggcatgac ttttttcaga tgcttctgat tctcccgtca aaatcgattc ttccactaat
    47401 aaatcatgtg cttcgattaa tcggatatct gctggaacga catctccggc acgtaagaca
    47461 atgacatctc cttttaccag ttctttcgca gggatttttt cttgcatccc gtttgatagt
    47521 actatcgctt cttgtcccat cagctgcttc aaaccattca atgattcttc cgcttttctt
    47581 tcttgccagt aactaacgag tccattgacg atcactacga ataaaataat acttccttca
    47641 atatattcac tagaagcaaa tttcaaaaaa gaggcaatga tcaacacgat catcagcaga
    47701 tcagtaaaat gctttgctat ttttttccat cgttttgtct gctgccttgc ttttatttca
    47761 ttatatcctt gatcagtcag gcgtttctgt cgttcttctt gcgacaagcc ttctgttgat
    47821 gtttgatagt ttttcaatac atcttctacc gtcaatctgt accagttcat cctatcccct
    47881 cctgtttaat tgatactgtt attatacgca gggaagtttt ttcaggcgta tcgattattt
    47941 caggggggtc tgaaataatt cgttttgcaa aatgtatctg ggcctaactg atatttctat
    48001 tgcttattct tttatataca aaatttaaga atacaaacca gataaccaat aaaaaaggaa
    48061 taaagcgtgt cgtgctttcg aataacaagc tgaaagcaat tgaagtaaaa aacaccaaca
    48121 aagcaagatc tttatatctt tgtgtagtgt tccgtttctt ttctttaata aattgaacat
    48181 gtgcacacaa gatcgaagac cacacaaata gaaaacaact cgttgtcatg cctgccaaaa
    48241 gctgaaaaaa caatcgacta tcagctacaa aaaaatgtag acaaagaccg gcaaaaaata
    48301 acattcctgt aattaaaata ccgtgtaaag gtacgccttt cttagaaagc gcacaaaacc
    48361 aatggggcaa acttttttct tttgctgttt gatataaaat cctgctagta ctgtagactg
    48421 cactatttgc tgaggacaaa gaagcaacca aaatcattag attgacaatt gctgctccgc
    48481 cttggcaatg gatcacttgc agcatagtca ctaaaggact ttcttttaaa tctaaacaat
    48541 gccatggaac aacaaataaa atcgacaaaa tcgttcctat atagaaaaag agaatacgcc
    48601 aaggcagaca gttgattgct tttttcaaat tcttttgcgg atcacttgtc tcgccaacgg
    48661 ttaagccgat catttcaatt ccagcaaaac tgaataaaac cataggaaat gagactacca
    48721 ttccagcaaa gccaaacggt agtaattcat cgatctgtcc aaaattttct ttgattccga
    48781 tagactgggt atgaaaatct gagacactca atcctatacc caataagata aaaaggaaaa
    48841 tccccaagat cttgatgatt gagaaaaaag attccaattc accaaaccac ttgactgcaa
    48901 caaggttgac tgccattaag atcattagtg cgctacctcc gcttatcaaa gctggtacat
    48961 gtacaaacca gaaatggata tacaatccta ttgctgttaa ttccgcaagt ccagctccaa
    49021 gccagcaaag ccaataagtc caattgacaa aaaatgccca ctttttgcct aaataatagt
    49081 caacgaaatc actgatagag ttaaatgtac tatttgctaa aaataaatca cccatggccc
    49141 gcatcaaacc ataaatagcc aaaccgcata tcaaataaac gagaataaca gctggccctg
    49201 ctgatgcaat tgcctttgct gaacctaaaa ataatcctgt tccaattgcg ccacctaatg
    49261 cgattaactg gatatttcga ttagttagag tccgtttcat tgccggtttt tccatcaagt
    49321 tcaccttttt ctttttcaag cagcatggcg acttcctgtt cccaagaagg tttctttatt
    49381 ttttcaatac agagtggtac tacaaacaaa atgacactga tggctgtgac tgcaattaga
    49441 ttgatccatg ttccagcttt catcgtcagt ccgacagaaa atccgattgc cgcaaataaa
    49501 acaataacga cagtccaaac tccaagattg ctctttttct ctttttttcc aattctaaat
    49561 ggtcgattca actttgcatg tgtataacgc aatctcaaaa ctgcgatccc catgatgaca
    49621 tagacgatac agtagataac agtagttgaa tttacgagca tcaaaaatgc ttgattgacg
    49681 ccaggaatca gcaaataaaa aagtgcaaag attgagataa tgacagactg agtcaaaata
    49741 acggatttgg atacgtcaaa ttgattcgtc ttccaaaaat tgaattttgg tggatacgca
    49801 ccttttctag cactttctgt cactgtcttt gctggtcctg aggcccaagc agataattgg
    49861 actgctacac caatgaagac aagtaaacta aacagattca caataagatg tggcaaacca
    49921 agaatttggc aataaatcga aatagattgc gcgatattat tcaattccat ttgtcctttt
    49981 ggtacgacat ttgctacaac taaagcattc aaaatattga cgaaaaatat aaaaattaac
    50041 gcggcaaata ctccgcgaat atacgtttta actggatttt ccaatcgagt gatatacaca
    50101 gaggacattt cgataccagt aaaaataaac atgatcggcg caaaataaac aaatgaggat
    50161 gcagtcgtag tatctggtat taatttgtcc catgaaaaac tgcctaatgt tccggttggt
    50221 acgatcccaa ctttgatcca cgcagcaaac cctaataaga gcatcatcgt caaaggcacg
    50281 tacaatccta accaaacacc gacttttccg ccgatttttg ccatatcaaa tttcaaattc
    50341 aaaaaagtga tgatccaata aacgactaaa atgacaacta atgtaaattt gctgttcaaa
    50401 ccaagcggca cattatcgat aatattacca aacaacggag cgagtgctga agcgaccatc
    50461 accatcccag gaaacatttg gacccataac agccatgaga caacgaaccc ccattttttt
    50521 cctagagcat tcgataccca aagttctgga ccaccttttt ggggaaacat tccagcaaat
    50581 tcaccagaga tcaatgagat tggaaaagcg tacaataata ctgcaaccag catgtaaaaa
    50641 atcatcgtcc agctcgttgc tgctacatct ggaatatttc gtacacttgc tacaagggcg
    50701 caggtcattc cgataaaggt catggtcgtg atttgctttg atgaaccagt atctttcatc
    50761 tttattcctt ctttcaatag cgacatatgt ttttgttttc ttttattttt gttcaagaac
    50821 agaaatgaca aggtttcatc gattcagtac aaaacccagt atcaccgaaa catccattga
    50881 acgatcttag tgaactgggt ttgatacatg aaacgaacga tccaacttat agaacgtttt
    50941 ataaaaaaga atatcttggc gaggaatata tgaaaaacag ggggaaatac aattgttttg
    51001 atgaagcaaa taattgtctg ttctccatat gtctcttgtt attctttcac acaaaaatca
    51061 gttctattgg atgatttcgt ttagtttctt ttccattgct ttggcgattt tttttgtata
    51121 aaaattgaaa attcgatcat cattcaaata aggagtcatg atagccgcac gtagcagagt
    51181 gattttctgt tcttttttcc attcttcttt cgttagaccc attctttcaa caaaacgaat
    51241 cggagaatca ccgtaatctt cttgtgtaaa tgtagtatga gaagtaataa accgttcacc
    51301 ataaacatcg ccatccatat aagaagaccg atcgaacatt ttttcattta attcattgat
    51361 agcgttcaaa tctgtacagc cttgttcttt gaatacccaa ttgaccatat taaaatcagg
    51421 atgattcaat ggatagactt cgattgtttt tcctttaaca gtaaaagtca gatgatcgag
    51481 aaattctctg aatctttgag ctgcctcgat tgaagcccca atcaattgac catatccggt
    51541 cacattcaat ggcaatacac gatgtgctgt ccagactgcg gcggcggttg ctccagcttt
    51601 tgatccttcc aaaatataag ctcctaacat atctggagcc tttactgatt tttcaaacac
    51661 atatggcgcg aaataagaaa tgatatttct catattttta tgtttgatta cgattcctcc
    51721 agcagcataa gggacatagc ccatcttatg aggatctatc gtgacagaat ccgcttctga
    51781 aatagctctg aacccttcat atacctcttt gtcaatcgtt acgcagtggt ggaaaacatg
    51841 atgttcttca aagaattcag ctaaggaagc atacggcaca aattctcctg cttcgtttag
    51901 aaacagtgaa cgcgcatagc cgccatatgc ggcatcaaca tgtaaataga aatagatccc
    51961 ttcatctttt aacctttctc ttaattggac gattttatct acactgtcta cttgaccttc
    52021 ttctgtcgtt cctacgacag caaccacacc tagaattggg attttttgtc cagctaattc
    52081 acgaattgtt ttttccaaag cattaatatc cattcgataa tcctcttgaa ctgggatagc
    52141 aaccatctga tctaagccga ctccgcaaat atctaacgcc ttcatccaag aatagtgttt
    52201 tgtttgaggg accagccatt tccctaatct ttggatattt tttccgctac gggaagaagc
    52261 tgctttgacc tcatccattt cttcgtccgt aaagctttcg gtcatttcca aaatttcttc
    52321 aacagataaa ttcaaaagtt cccactcaga catttttttc actttttcag gcagcacttc
    52381 cttgacagct aaaggaatcg atttgatgca acgggcgtac cataatcctt caagattagc
    52441 aatagaacca tctgctgcaa tgtgtcccca tccgtctgtc atattgaata atgaagcaaa
    52501 atcctgtcct acttctgctt ccatttgcga agttgccata gaagattcca atgcaacatt
    52561 atttgggttc cacagcatcg catagttgta agctaataaa gcaggcatca atgtttcagc
    52621 attcatttgt ccccagtaac ggcctgctga atgccatggg atcgatcctg cgcgtaatcg
    52681 ctgactgact tcatccaaga cctctatcat atggtcgcgg gtggctagat aatctggagt
    52741 gagcttatct ccttcgctaa ttgcaggcat atctgaagga atataatttt ctctccatcc
    52801 aagatgttca tctaccatct tgttcaacaa cattttataa actggtccat tttcagcttt
    52861 gtcgcctata aagacggcct tgatatccat atctttcatt tttcttccct ccatattttg
    52921 ttggtcaatg tcttgcagat acatgtgttt atctgtaaca cctcttcact atagcgccaa
    52981 aaatgagaat ttttttttta taacatcaaa tccacgtaga tttttacaaa caaaaataaa
    53041 taaagtcgga tttttctgat aattcaacgc aaaaaagcga acaatttttc aataaatcag
    53101 tcttctaaaa tagataacct aaaaaaagcg aacaaacaaa taaaatgact gtccttcatt
    53161 cactaaacat atttttattt ttttatattg ttaaaaattc gcaatttatt ttttaataga
    53221 attatctgtt ttccaaattt tataacataa aaaacctttt ttaacggcat ttatatgctt
    53281 tttcagaaat taactgatga tttcaaaaag aaaacatgtc ataatatttc ccatattgtg
    53341 caaaaaaata caaggcggag gctctactat gattgaagaa tatattgaga aaaatatttt
    53401 aagacagctg tttttatgtg ggcaattcta tgtaaataaa gaagtcaatc tagaaaagct
    53461 ctccaatctc ctgcatgttt gcaaaaccac tttactcaat gatatcaata acataaaaaa
    53521 agaatttgaa gaacagatcg cttatacaca tcgggaaaag gaccgttaca ctttatattt
    53581 ttcagaacat atacctcgat gcaagatcat gcagcaattg tctcaaaatt cgttgttttt
    53641 aaaaacttgt ctgctttatt tggaagaaga tgaacctgat tatcttcaat taactgaatg
    53701 tgaattcatc tctgtcagca aagcttattc attaaaaaaa caagtattag cttattttaa
    53761 tgactgcggg atcgaaatcg accgctactc ccctcgattc actgaaatgg aaagacgtct
    53821 gctgcttctt aatgtgtcgt atcgtttagg cggttttaat tcttgggagc tacctgaatc
    53881 gttttttgaa cgtgccgatc gtttcattga atccgtaacg gaaaatagtg gcagatttta
    53941 tgataaagaa aataaagaaa tcttatcgat tggttttgct atcagtttcc tacgccagca
    54001 agtgtgtgct gtgacaatag attcaaaatt tatcgaagaa atcaaaaaac gtcctattta
    54061 caattatgtc gaatcagcat gggaaaacac tgatttccaa acctattata aaaaagaaga
    54121 attcgccttt attttgacac tattcaatct ttgtaattat ggtttccatt cttatcagtt
    54181 gattgcggaa gactttcaac agctacacca agtgtttatt gacaatactc ccgaaataaa
    54241 agaactagtt gctacctttg aatctcactt caatcaagaa ttattcggaa accaaccgtt
    54301 cgaacgtgcg ctgattcatc tgatgcgttc ggcttgggat aactatcaat tattcatgcc
    54361 agaaaaattt tatcttttaa atgaggaaca gacaaattta tataaagaag tccagacaat
    54421 tttttccagc tggtccagcc agttacctta tgatctacgg ttgaatccta attgcatgcg
    54481 ggcttttgtg atcgaattga gcggaattct ccgtctgaca aaagaacatc tgactatcta
    54541 tatcgtcaca aattcggatg ttcattatct gatttatcgg gaagccttgg aagctgtaac
    54601 tactttcgat tttcaagttg caccaacaat ttattcaagt atatctgata taaagaagta
    54661 tgcgcagcag tcctcaaacc gggtattatg tgaacgtaca ttatatacac cagatgcggt
    54721 ccaatatgaa aatattattc ctatttcgat caatacgatc gatcgagcta tcatttcagc
    54781 tgtgcaaaac aaataagggg ctgtgacaaa aatcatgtca cagcctctta tttgttgaag
    54841 atgcccattt ctgtaacaat ctcttgatac acgtcaggct cacaacctca cttattttgg
    54901 acatctacgg gtccgatctc tttatttaaa aaataagaaa tgatggttcg gataactacc
    54961 aacgccgcta gttggaaaat atcctgcaag gtaggtttga taatcgattc gatgatccca
    55021 gctgaaacaa gaatttccaa acttagaagt atatagcctc ccaacatctt tttaatagca
    55081 ttgttctcgc tgactcggtc gctttgcact tttgtatgga caaataaata tttcaaaaaa
    55141 tccttgattg atagacaaac accccaaacc aataaacaga tagcaaagat atcaagtccc
    55201 agtacaagtt tttcgaaata tggaagaaga aactgcatca actctgtcgt catcctacct
    55261 ctcctcttct ttgtttttct ttgtcttcta tttcctgatt caagaaataa gaaatgactg
    55321 ttcgaatgat aataataagt gcaagcttca aaatatctgt ccaagtcggc ttgataactg
    55381 actcgatgat atcagcaacg actagtactt ccaagcttaa caaaatataa cttgctagca
    55441 gttttcttgt atctgcatta cgagtattac gttctgcata gtttttcttg acatgagacc
    55501 aatcaaaaag tttgaataga acaagaacga tcccgacaat taagataccg atagaacaaa
    55561 tatttaaaat agcaatgatc cattctagaa attcaattaa atttgagcga aacatatacg
    55621 ctacctactt tcttttaatt tgttcctatt cttttattgt aaaagaaagt taccttgttc
    55681 gtctatttaa aagttgttct aatgataacg gttcgcttaa atttttcttt ttcactctcc
    55741 catttttctc cctccatcca taaatcgtgg aagtatccaa aacaacgtag caagttaaaa
    55801 taaggcttag tccgtcatca gcttttcaaa gaagcactgt ctcggtgctt tttttgtacc
    55861 caaatttcta aaaatagaac catacacctc ctcaaatctt ttcttcttac ctaccctatt
    55921 tttatttaca ggaaaatcag acacttcttc ttttttgtca aaatttcctt tttcttctcg
    55981 tcctatcatt tggcattcta ataaaaacga actatccttg gatatagaaa gagaaaacaa
    56041 ggaggcgttt ttcatgagta aaaaattaat caaagtcggc atcggtttag gtttgcttgc
    56101 ccttggcgct gcatatctag gaaaaaagac aggactattc gaagatgaca gtcatttata
    56161 tgatgaattc gaatcaatct agcatcctat ttagttgaat cactacggac atacttggaa
    56221 gacattggag gaatcacaat gagaaaaagt aaagcaataa tgattggtgc cggtattgcc
    56281 aatatggcag cggctgttta tttgattcaa gaaggcaaat ggaaagggga tcagatcacc
    56341 ttttattcat tggatgatca cggttcaaat gatggtgcac cgaccgacac tgtagtggat
    56401 gaatattgga ataaaaacca tccattagaa aaccaaaaag gctatattgc tcgaggcggt
    56461 cgcatgctta attaccgtac ctatgtagat ttgatggatc tgttaagtcg aataccttct
    56521 gttactgagc cagggatgac tgctgaagaa gatacgagag attttgatgc aaaacaccga
    56581 acctttgaca aagcacgttt gatggaaggt ggcaaaggaa tcattgatgg cggaaaactg
    56641 ggattcaata ataaagaccg tattcttctg actaaactga ttgctatgcc tgattcagaa
    56701 gaagaaaaac tagacaatat cactatcgaa gaatatttca aagatgatcc acactttttt
    56761 gaaacaaact tctggtttat gtgggaaaca acatttgctt tcagaacacg tagttctgct
    56821 caagaattgc gtcgctatat gcatcaaatg atttatgaat tcactcaaat cgaacatcta
    56881 gtgggcgtca atcgaacacg ttacaatcaa tacgaaagta ttatgcttcc tttgatcgag
    56941 tacttgaaag aacaaggatg caaaatcatt ttgaaccgcc gtgtcactga ctgggaattc
    57001 aaagaaacac cgatgcaaga tgaaatcact gtgactggtt tgaaaattac caatacactg
    57061 actcaagaag aagaatacgt tgtggtcgat gaagatacag cagttatttt cactaatggg
    57121 tccattacag attcagctac tttaggagat tacgaaacac cagctgtaga aaatatggat
    57181 tatggtgcag cttctagtct ctggaaaaaa gccagtgaac gtttctacaa cttgggaaat
    57241 cctgacaaat tctttgctga tcgagatgca agcgaatggg tcagctttac cctgacgacg
    57301 aaaaaccatt tgttgttgaa tgaaatcacc cgtatcacga ctcaagaacc aggaaatgcc
    57361 ttgaattcat ttatttcaac cacaccgatc acgccgttag gccaaaaaga tgtcaatatg
    57421 tctatcgtcg tgcatcatca accgcatttt acgtctcaga aaccaaatga aacagttatt
    57481 tggggttatt tcctttatcc aagacgacgt ggcgaatttg tggataaaca gtatattaaa
    57541 atgaatggaa aagaaatgct agaagaactg attggacaac tttcaaaagt agatcctgga
    57601 ccagtgaata ttcgtgaaaa agaaacagaa attttcgaca gcgtaataaa taatatccct
    57661 gtctatatgc cttatgcttc cgcgttgttc aataatcgtg ccaaaagcga tcgaccaaaa
    57721 gtcattccta aacattcgac caatctggcc tttacaggag aatttgtcga gcagccttat
    57781 cagatgatct ttactgaaca aagtgctgta cgttctggag aaatcgctgc tttccatttt
    57841 gcgggtattc ctatgtcccg tcttgtcaaa acaccgcgtt acgacaaaga tattcctact
    57901 ctagctcgtg ccgcaaaaaa aatgtttgaa taatcaagag gttgtgaaaa agctgccctg
    57961 catcaagtaa taagaacaac caggctaaaa cagcttctta tgtttttgat ttggttggac
    58021 ttattaccgc agatgcaagc ttttgaacac cgtttaccaa gaggttgtga aaaagctgcc
    58081 ctgcatcaag taataagaac acccaagcta aaactgcttc ttatgttttt gacttggttg
    58141 gacttattac cgcagatgca agcttttgaa caccatttac caagaggtta tgaaaaagct
    58201 gccctgcatc aagtaataag agcagccaag ctaaaacagc ttcttatgtt tttgacttgg
    58261 ttagacttat taccgcagat gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa
    58321 ggcgtttagt ttcgagtatg aagaaaaatt ttgtgaaaat ggttcctcac gtttttgcat
    58381 aaatttgact taataccgag aaactgatcc cttctgtcat aacctctttt tatttatgtc
    58441 tgtttctttt tgaaaacaac tattttttca acgtttactc tcttgccaat ccaacatcat
    58501 ctaacggata caactatttc aatgattacc attacactaa aaaatcggaa acacacctct
    58561 ccgaacacaa atacataaga ctatagaatg tttcatttaa gaaaaaaagc gtttcattat
    58621 caaaaaggta agatctcctt taaaatgaaa ttatctgtag tactaataat gcagacaatt
    58681 ttatgaatct gaaaggagca tctccaatga aagcagtcac ttggcaagga aaacagaaaa
    58741 tggaaatcag aaacgtagat gatccaaaaa tattagaacc aacagatgca atcatccgta
    58801 tcacagcaac agccatttgc ggctccgatc tgcatcttta ccatcatggt gaagcagttt
    58861 tggaaaaagg gtatgttgta ggacacgaac caatgggaat cgttgaagaa gtgggatctc
    58921 aagttcaaac attgaaaaaa gggcaacgtg tggttatccc ttttaatatt agttgtggtc
    58981 attgtcattt ctgcctgaat cacatggaaa gccaatgtga tgaatcaaat ccagatcagt
    59041 tatatggcgg gcttttcgga tttggcaagt tgaacggtaa tcattggggt ggtcaagcgg
    59101 aatatctaag agttccttat gcagactcta cttcatttgt tgtaccagat aatgatcttc
    59161 ctgatgaaaa agttttattt ctatcagata ttttgcccac agcttattgg agcgttgaaa
    59221 acgcaggagt aaaaaaaggc gatacagttg tgattctagg ttctggtcca gtcggtctat
    59281 tcgctcaaaa attcgctgtt atggctggag cagagcgcgt aatcgcagta gatccagtac
    59341 agcaccgtct agataaagcg gctaattaca atggggttga aacttatttc ttagaagaca
    59401 cggcacaagc tggaacagaa ttgtatgaac tggctaaagg tggcgcagat gtcattatcg
    59461 attgtgtagg aatggacgga ttagagcctg tcaaagaaaa agcgaaaaat ttagtaagct
    59521 tacaaagcgg cacaatctct ccattacaga tggcatcgca agctgtcaaa aaatttggaa
    59581 cagtccaagt aactggtgtt tatatgactc cagcttcttc ttacccgctg caagaatttt
    59641 ttatgcggga tatcgctgtc aagcatggac aggcaccaat tatccatcta atgccaaaaa
    59701 tttacgcaat gattgcagaa ggactattcg atcctacaca aatcattact cattcgctgc
    59761 cactatcaga agcagcacaa gcatatgaga tctttgacaa aaaagaagat aaaaatataa
    59821 aagttgtttt gaaaccttga attcagtaaa aaatacaggt gattttcttt atgcccaaaa
    59881 tcaaacgaaa tacccatgag atcgaaatag gaaaagaaga agatatcgaa atacgaggac
    59941 gtcgcttccg cttctatttc caaaatcgtt acacattgat ctcactggct gtcgatttat
    60001 taaccgggat tttctatatt tttggaagcc ttgcttcctt aactaaaatc cccgatcgat
    60061 atggcaccta tttttatttg gctggtgcta ttttcttgac gattcgtcct attctcagaa
    60121 tcgtaaggaa catttttatt tacgacgaaa aaaaagcaat gaagagaaca agcaaaaaaa
    60181 aagaggcatg agaatttttc aaatctcatg cctcttt
//
LOCUS       DBBGRF010000012        59859 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000012 DBBGRF010000000
VERSION     DBBGRF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.012"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..384)
                     /locus_tag="ACIZD4_000830"
     CDS             complement(<1..384)
                     /locus_tag="ACIZD4_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989783.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKI"
     gene            complement(569..967)
                     /locus_tag="ACIZD4_000831"
     CDS             complement(569..967)
                     /locus_tag="ACIZD4_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HGC5989784.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(964..1737)
                     /locus_tag="ACIZD4_000832"
     CDS             complement(964..1737)
                     /locus_tag="ACIZD4_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HGC5989785.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1734..2417)
                     /locus_tag="ACIZD4_000833"
     CDS             complement(1734..2417)
                     /locus_tag="ACIZD4_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HGC5989786.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2584..3471)
                     /locus_tag="ACIZD4_000834"
     CDS             complement(2584..3471)
                     /locus_tag="ACIZD4_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5989787.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3468..4337)
                     /locus_tag="ACIZD4_000835"
     CDS             complement(3468..4337)
                     /locus_tag="ACIZD4_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5989788.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4474..5760)
                     /locus_tag="ACIZD4_000836"
     CDS             complement(4474..5760)
                     /locus_tag="ACIZD4_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5989789.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            6033..6611
                     /locus_tag="ACIZD4_000837"
     CDS             6033..6611
                     /locus_tag="ACIZD4_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC5989790.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6611..7540
                     /locus_tag="ACIZD4_000838"
     CDS             6611..7540
                     /locus_tag="ACIZD4_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989791.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7537..9273
                     /locus_tag="ACIZD4_000839"
     CDS             7537..9273
                     /locus_tag="ACIZD4_000839"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC5989792.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(9336..10172)
                     /gene="pheA"
                     /locus_tag="ACIZD4_000840"
     CDS             complement(9336..10172)
                     /gene="pheA"
                     /locus_tag="ACIZD4_000840"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGC5989793.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(10169..10678)
                     /locus_tag="ACIZD4_000841"
     CDS             complement(10169..10678)
                     /locus_tag="ACIZD4_000841"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGC5989794.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10671..11966)
                     /gene="aroA"
                     /locus_tag="ACIZD4_000842"
     CDS             complement(10671..11966)
                     /gene="aroA"
                     /locus_tag="ACIZD4_000842"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGC5989795.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11979..13070)
                     /locus_tag="ACIZD4_000843"
     CDS             complement(11979..13070)
                     /locus_tag="ACIZD4_000843"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGC5989796.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(13087..14253)
                     /gene="aroC"
                     /locus_tag="ACIZD4_000844"
     CDS             complement(13087..14253)
                     /gene="aroC"
                     /locus_tag="ACIZD4_000844"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGC5989797.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(14255..15319)
                     /gene="aroB"
                     /locus_tag="ACIZD4_000845"
     CDS             complement(14255..15319)
                     /gene="aroB"
                     /locus_tag="ACIZD4_000845"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGC5989798.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(15352..16374)
                     /gene="aroF"
                     /locus_tag="ACIZD4_000846"
     CDS             complement(15352..16374)
                     /gene="aroF"
                     /locus_tag="ACIZD4_000846"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGC5989799.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(17033..18007)
                     /locus_tag="ACIZD4_000847"
     CDS             complement(17033..18007)
                     /locus_tag="ACIZD4_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HGC5989800.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17988..19871)
                     /locus_tag="ACIZD4_000848"
     CDS             complement(17988..19871)
                     /locus_tag="ACIZD4_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HGC5989801.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19889..22114)
                     /locus_tag="ACIZD4_000849"
     CDS             complement(19889..22114)
                     /locus_tag="ACIZD4_000849"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGC5989802.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            22229..23263
                     /locus_tag="ACIZD4_000850"
     CDS             22229..23263
                     /locus_tag="ACIZD4_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5989803.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(23330..24343)
                     /locus_tag="ACIZD4_000851"
     CDS             complement(23330..24343)
                     /locus_tag="ACIZD4_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC5989804.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24421..24609)
                     /locus_tag="ACIZD4_000852"
     CDS             complement(24421..24609)
                     /locus_tag="ACIZD4_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HGC5989805.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(25049..25177)
                     /locus_tag="ACIZD4_000853"
     CDS             complement(25049..25177)
                     /locus_tag="ACIZD4_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGC5989806.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(25180..26553)
                     /gene="rlmD"
                     /locus_tag="ACIZD4_000854"
     CDS             complement(25180..26553)
                     /gene="rlmD"
                     /locus_tag="ACIZD4_000854"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGC5989807.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(26664..27719)
                     /locus_tag="ACIZD4_000855"
     CDS             complement(26664..27719)
                     /locus_tag="ACIZD4_000855"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HGC5989808.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(27729..29159)
                     /gene="gatB"
                     /locus_tag="ACIZD4_000856"
     CDS             complement(27729..29159)
                     /gene="gatB"
                     /locus_tag="ACIZD4_000856"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGC5989809.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(29156..30628)
                     /gene="gatA"
                     /locus_tag="ACIZD4_000857"
     CDS             complement(29156..30628)
                     /gene="gatA"
                     /locus_tag="ACIZD4_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGC5989810.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(30628..30933)
                     /gene="gatC"
                     /locus_tag="ACIZD4_000858"
     CDS             complement(30628..30933)
                     /gene="gatC"
                     /locus_tag="ACIZD4_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGC5989811.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(31039..33075)
                     /gene="ligA"
                     /locus_tag="ACIZD4_000859"
     CDS             complement(31039..33075)
                     /gene="ligA"
                     /locus_tag="ACIZD4_000859"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGC5989812.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(33092..35326)
                     /gene="pcrA"
                     /locus_tag="ACIZD4_000860"
     CDS             complement(33092..35326)
                     /gene="pcrA"
                     /locus_tag="ACIZD4_000860"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGC5989813.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            35481..37040
                     /locus_tag="ACIZD4_000861"
     CDS             35481..37040
                     /locus_tag="ACIZD4_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HGC5989814.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(37151..39082)
                     /locus_tag="ACIZD4_000862"
     CDS             complement(37151..39082)
                     /locus_tag="ACIZD4_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGC5989815.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(39100..40014)
                     /gene="pfkB"
                     /locus_tag="ACIZD4_000863"
     CDS             complement(39100..40014)
                     /gene="pfkB"
                     /locus_tag="ACIZD4_000863"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGC5989816.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(40011..40763)
                     /locus_tag="ACIZD4_000864"
     CDS             complement(40011..40763)
                     /locus_tag="ACIZD4_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC5989817.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(40922..41131)
                     /locus_tag="ACIZD4_000865"
     CDS             complement(40922..41131)
                     /locus_tag="ACIZD4_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989818.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(41142..42470)
                     /locus_tag="ACIZD4_000866"
     CDS             complement(41142..42470)
                     /locus_tag="ACIZD4_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989819.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            42606..42761
                     /locus_tag="ACIZD4_000867"
     CDS             42606..42761
                     /locus_tag="ACIZD4_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGC5989820.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(42835..43422)
                     /gene="yihA"
                     /locus_tag="ACIZD4_000868"
     CDS             complement(42835..43422)
                     /gene="yihA"
                     /locus_tag="ACIZD4_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGC5989821.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(43505..44755)
                     /gene="clpX"
                     /locus_tag="ACIZD4_000869"
     CDS             complement(43505..44755)
                     /gene="clpX"
                     /locus_tag="ACIZD4_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGC5989822.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(45002..46291)
                     /gene="tig"
                     /locus_tag="ACIZD4_000870"
     CDS             complement(45002..46291)
                     /gene="tig"
                     /locus_tag="ACIZD4_000870"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGC5989823.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(46445..47377)
                     /locus_tag="ACIZD4_000871"
     CDS             complement(46445..47377)
                     /locus_tag="ACIZD4_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989824.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHQVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(47534..48193)
                     /locus_tag="ACIZD4_000872"
     CDS             complement(47534..48193)
                     /locus_tag="ACIZD4_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HGC5989825.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(48196..49221)
                     /gene="sppA"
                     /locus_tag="ACIZD4_000873"
     CDS             complement(48196..49221)
                     /gene="sppA"
                     /locus_tag="ACIZD4_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HGC5989826.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(49234..49524)
                     /locus_tag="ACIZD4_000874"
     CDS             complement(49234..49524)
                     /locus_tag="ACIZD4_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989827.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            49933..51738
                     /gene="glmS"
                     /locus_tag="ACIZD4_000875"
     CDS             49933..51738
                     /gene="glmS"
                     /locus_tag="ACIZD4_000875"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGC5989828.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(51810..53165)
                     /gene="glmM"
                     /locus_tag="ACIZD4_000876"
     CDS             complement(51810..53165)
                     /gene="glmM"
                     /locus_tag="ACIZD4_000876"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGC5989829.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(53189..54358)
                     /locus_tag="ACIZD4_000877"
     CDS             complement(53189..54358)
                     /locus_tag="ACIZD4_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGC5989830.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(54355..55242)
                     /gene="cdaA"
                     /locus_tag="ACIZD4_000878"
     CDS             complement(54355..55242)
                     /gene="cdaA"
                     /locus_tag="ACIZD4_000878"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGC5989831.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(55431..59123)
                     /gene="nifJ"
                     /locus_tag="ACIZD4_000879"
     CDS             complement(55431..59123)
                     /gene="nifJ"
                     /locus_tag="ACIZD4_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HGC5989832.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            59322..59843
                     /locus_tag="ACIZD4_000880"
     CDS             59322..59843
                     /locus_tag="ACIZD4_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HGC5989833.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT        16587 a        12998 c        10739 g        19535 t
ORIGIN      
        1 aatcttttgc tgacgtctaa aaatagaaaa agaattttcg tcatctattt gataacgcat
       61 ttgtttttgc agttctgctg cagtcagatg gatcttccca tcgtttgtat cgatcattaa
      121 accttctgga aacagttcaa ccactgctcg atcccaagat tcaagagaaa gctcgatata
      181 atcttttact ggtaattcca attctacctt aaaaaagtgc aaaacagccg acagcccttc
      241 tgcttgatag atttctccta atgttagccc ctctagatgg aactctggtg aaaaatgcag
      301 caatgtttta ttttcctgca attgaacata tagaaatgta gatcgctcaa tcagagtatc
      361 ttttaaaaca actaaaaaat tcatttttct cccccttttt tcatcatttt taaaatagca
      421 tattttgaaa agaaagtctg atgcttagag tagaatttca taaaaattta ctatttcata
      481 agtattcacg agaaaaatac aaacaaaaaa gcggaaataa cgctcatccg ccttcttgtt
      541 tgtgtttatt tcctcttcaa acgcttgtct atgattcaga cttttctcta tcgttatttt
      601 catctaaaag ttcttgcatt ccgataattt ctcgatattg atgaatctta gtgataccaa
      661 tgactttgtc tacatcaata ctaaaacaaa taccattacc tggaatatcg atgttgatgc
      721 cttgaccaat cgcatccatt actttattcg tcaaactatc gggtactaat gtcaacacaa
      781 tatctttttc tggcgaaatg tccaaaccta aaaatttccc tgaatcatgt acaccagaac
      841 ctcttccatg taagatcgtt ccgcctgctg cacctgcttc ttttgaaaag tcgataacat
      901 cttcgcccat tcctccgtca acgatcgtca caatcatgtg aagattcaat gctacaagat
      961 ctttcatttg ctttccccca atttttgcaa tctttctttt tcgattctgt ctttttcatc
     1021 ttttcgttta taaatatatc ctagtactaa agtggataat attggtgtca atgcaatcat
     1081 tgcaaccaca ccaaacccgt caatgatcgg atctcttcct tcaatttgtg cagcgattgc
     1141 cacgctcatt gataaaataa atgtcgaaca catcgggccc gttgctactc caccgttatc
     1201 aaaagccatt gctaaaaaga tcttgtccac ttttcgtcct aaaataaatg ctagcccgta
     1261 tcctgggatc aagaaataat aaagagagaa tccgacgagc aaacgccaca tagacaatcc
     1321 tactgctgcg ccgatcccaa ttgaaattac catcagcatg attttcgatc ggattctccc
     1381 ctcgctcaat tcttcaacct gtttgatcat tacatgaatc gccggctcag caaaccctac
     1441 taagaacccc attaaaaagc caaggggaac cagtatataa ttgtaaggca atcccgcaat
     1501 agcactgcct aaatgctgtc ctaccggtac ataagccata ttgactccgt gcaggaaaag
     1561 gatcaaccca atagtcgtta tcaagaaacc tttcataatg tcaaagaaac gctttttgcg
     1621 catacgaaaa ctaatgatat tcattaaaac aaataggatt acgataggtg ccactgccaa
     1681 aatgacttcc atggtaacga tttcgattcc atctatcact tgctgccaga aactcattgg
     1741 aagatcaccc ccaaaatcat cacggcaaga atcggcccta acgaagcaat accgaccatt
     1801 ccaaaactgt cattttcatt tttcttttgt ttgatcatac tagtcatccc tccggcaagg
     1861 gccaagataa atggaacagt tactggacca gtagtcactc cccccgaatc aaaagcaatc
     1921 ggcataaatt cggaactggt gaaaaatgag gcgatcaaaa cgcctatgta gcctatagcc
     1981 atcaattgat aataggatag cttgaatacg acccgaagca gcgcaaaggc tagaaatact
     2041 ccagtgccga cgctgacgat cccaatcagc aacactctgc caatctctcc gtcagatata
     2101 tcatatactt gttgtcccaa aacttgcacg gaaggttcag caatcgtgat cacgatcccg
     2161 atagcaaatc ccaaactgac caaaacggtc aaacttttct ttttgatcat atatttccct
     2221 actagatctc cgacttccat catagaataa tctgctccaa acaaaaagag cgtcattccg
     2281 atcatcatga ttgccgcacc aaccagaaat gaagcgaggt cttctccttc taacggtgca
     2341 aaaacaaacg ttaaaatgac aatcaggaca gtcatcggca atatagcagc aatcacttct
     2401 ttaaaatttt ttagcatgta tcctcctcct ttactcttta agtttacctt aaaatgaaag
     2461 agttttcgag cacaaactta aaacgttatc atttaatttt tctcaacata aaataacaca
     2521 cgtcccaaaa gtatcttttt acttggaaaa atgactttga aggaacgcgc ttattgtgtt
     2581 tttttatttt acagagccga tcattccttg aacgaattgc ttttgcaaaa caaaaaatac
     2641 gatggcagtt ggtaaagtag cgatgactaa tccagccatg atcattccat agtctggtgt
     2701 ataggaagca cccatagcag ataaaacaag cggaaccgtc cgtttatcag gagattgcaa
     2761 agctactaag ggccataaat aattgttcca gctactcatg aatgtgatga ttgcagccgc
     2821 ggcataggta tttttagccg tcggcatata cactctaaaa aaaatactta gttcttttag
     2881 accgtctaat cgagcggctt ctactagatc ttttggaaaa gatttaacat tttgtcgaaa
     2941 gaagaagatc aaaaaagcag tgctaacaga tggcaggatg acaaccaaga aactgttgat
     3001 tcccaaaacc gttccgttca attgtgaaaa cattcgatat aaagggatca tcaatgccgc
     3061 aaaaggaacc atcatcgata gcagtagaat attgaaaatt aggtcttttc gtttactttg
     3121 ataaatctca aatccatatc ctgccattga cgaaatcagc aatgcaaaca cagtggtcac
     3181 caaagcgatc atcgctgaat tccaaaggga acgagtaaaa ttcagctcat tggaaaacaa
     3241 attttgaaaa ttgatgatca agttactgcc aatctttatt tttcccgatg tgatatccac
     3301 gggtgtattc gtcattccca aaaccatcca gacaaaaggg aaaatggaaa taaatgatag
     3361 gatgcttaat gctgtatact ttaatactga cccaattgtc gaacgaagtt ctaatgcttg
     3421 ttttttgacg ttggggcgtt cgattgtttc tttttctacc atatttttca tcgactttct
     3481 cctcctactt tcgtttggat tatcgacaat atcacaataa aggaaacaat aacaaaggaa
     3541 actgctgccg catatccaaa attaggcgtg aatttataac tcaaattata gatgtattga
     3601 gatagggtgg tcgttgcatt tgctggtccc ccgccagtaa tattttgtac ttcatcaaaa
     3661 agctgcaatg tcccgatcgt cgaagtaatg gaagtaaaca aaatgattgg ttttaaattt
     3721 gggatcgtca ctttgataaa ctgctgccat ttagaagcac cgtcaataga tgctgcttca
     3781 taaatctccg aatcaatatt ttgcatgcct gaaaggaaaa aaatcatatt gtatccagtc
     3841 caacgccaag tgatcgaaag aatgatcaga actctcgccc aaattggatg agtcaaccag
     3901 ccaatcggtg tgtcaatcat accaatgccc aacaacaagt tgtttacaag gccagattga
     3961 gaaaatagac ttttcatgat cagagaataa ctgaccatcg aagtgataca tggaagaaag
     4021 atagcggttc gaaacaaccc tttatatttc aactttttat catttaaaag gttggaaata
     4081 aaaagtgcta gaaacaacat gatcggtact tgtacaagta aatacaggaa tgtattaaaa
     4141 aaagcttttt taaaagttgc atctgtcaac atccgctgat aattacctaa cccgttaaat
     4201 gtcatattga cagggggacc actttgaaaa gacgtgatca aagccaaaac catcggaata
     4261 aaaaccatga ttgatatcaa aatgactggc aagattaaaa aagcatgccc gtttttgaat
     4321 aaatctttct gcttcattct tttccctcca attctatcat tgattatcta catgaaaaga
     4381 caagaaagac aatatctgta aggcagacgt gatctttttt gtcttttcgt ttgtctgatg
     4441 aaaaagcgaa gaaattcact tttttaccac cgatcaatta gccaattgtg cttctacttg
     4501 tttttgtgta tctgctagta ccttgtctgt ctcttctcca ttgatgattc gatgaagagc
     4561 ttcagctacg actgcttcaa ttgcataggt ctcatgtccg taattcactt ctggtatttc
     4621 agatgtccat gttgaaaaat cgtcaaagat cttttgacca ctgtaaaatt cagaagcttc
     4681 ttgataagct tcttgttcat tcgcgctaag catcgtagat actagtccga tttctttcgc
     4741 aagagtgccc atcagttctt cattcgaagc aaacgttgct tctaggaaat ctttcgctga
     4801 atcttctcca gctactcctt tgatcacata ccagccagcg ccgccaaggt tagaagcttg
     4861 cgctttttgc agattttctg gaagtgcagg tattggtgca atcttccatt ttccagattg
     4921 gttttctgct ccttggatcg ttgaagaata ccaagcgcca gttgggctag aagctactgc
     4981 tcctgattgt atcgcagtta ctccagcatt ccagtcagag gtttgttcga ctagatcttc
     5041 tttcaaaaga gtggcaaaca attcaagacc atactttaaa gatgcattgt cttggatcgt
     5101 gactgtctcc ccatcttcag atgtatacca ttctcctgcc tgttgcataa tcatccttac
     5161 tcgaccaagg tcagaaggat tgacttcagc gattttcttt cccgtctttt ctttgacatc
     5221 tcgcgctact tgaatatact cgtcccactt cagattctcc atatcctctt ctgtataacc
     5281 tgcttctgcc atcagatccg tacgatagaa gtttgctgtt acgcccgaat cgaaaggaac
     5341 accgtatatt ttatctccta ctttgtttac cgcaaattta tacggtgcaa aatgatcttc
     5401 ctttacaata gcagacaaat tagcgaatgc atctggataa gaagtcaaat agccttgtat
     5461 cctataatct tcaatcaaga cgatattggg caatccttct gtattcccgc tcgctaaagc
     5521 ggtgttcagt ttctgaacga tatcatcctg agacatcgta acaacttcta tctctgtttc
     5581 ttcgttctca taaacttttt ttgcttcatt cactgctttg atattgaatg tctcatccca
     5641 cgcccagaca gtgacttttt cttctttgtc tgctgtacta ctagcacttc cgcatcctgt
     5701 taagaaacct gatgctgccg ctaaacaaac gactccagca attaactttc tgatgttcat
     5761 ttttatccgc tccttttcca tccattagtt gtttacgttt gctacattca tcataccaaa
     5821 atttgaaaac ggtttcttta ttattcagat acttcaaaaa tttctcctaa aataataaaa
     5881 aaatacaaat caactatgac aaaaggaata atcttagcat ctagaccaaa gatcgaaatg
     5941 gtgaggtttc tttaaaataa aaatatcctt gcattttctc ctagaaataa gtatttttaa
     6001 attacaagac tattcttaag gcgggtaaaa aaatgccaat acgcgtaatt cttatcgatg
     6061 atgaacagac gattttagat ggaatgaaac agttgatcaa ttggtctgag cacgggtttc
     6121 aattaatagg gactttttcc agtccgctga aagcgcttga tttttctttg gtacatgcaa
     6181 tcgatatcgt ggtcacagat gtaatgatgc ctgaattaaa tggaatcgaa ttatcgcggc
     6241 tattaaaaca gcaacaacct gaaacacaga tccttatcct ctctagctat gatgaatttg
     6301 atatggttaa agattctttt aaagaaggcg tcgctgatta tcttttaaag cctcgattga
     6361 gtcctgattt ttttctaaat tccttaactg ccgtttcaca aaaaatcaaa aaaaagccca
     6421 acaaaagccc aatcaccaat cgttatgagc agatctgcga gaatctttca cagcagattg
     6481 ctggacaaac tcgtccattg cttgaccctc ttctttttga acacaccttg tttttctgtt
     6541 atataccgaa aaacggccat tcagttcaaa acaaggctct aaacaaaaac agtcgatcac
     6601 ccattcattg atggatagcg acgattcgtt tactatttat cctgtttcta ccttttcgga
     6661 agaatccggc tatgtaatca atactgattc caaagataca cttaggaagt ttgttcaaaa
     6721 gtttcgtcaa gaagtttttc caggtgattt ttttgttgtt tctgattctt ttgcaatcca
     6781 agatatcaat gaaatattcc aagagatcag aaattgcacc aaaggacaac gtttctatca
     6841 taagggaaag aaccttgctt atcagcatga acttcttccg ttattaacca accacgagca
     6901 gcaagcaagt agttatttaa caaaaatcgt tcataaagac tacgctttag ctgtcaaaga
     6961 acttgagaat ttcttcacga cgatattgga acagcctatt gatccagctt atttgaaaca
     7021 tgaggcaatc aatcgtttct atgcattact caacgctttg gctgacgagc atgttgggaa
     7081 tgaagaactt tctttgctca agatcgccct tccttcttta ttagccgatg ctgagtattt
     7141 cgaagatttt tctattcttg tcaaagaaac acttgagaaa ctcacccact tttctgcaaa
     7201 tgcaaaaaaa gacaatttcg atatcttgac tttgatctac gagttcgtcc aggaaaatta
     7261 tgagaaagaa atcaatttac aacttttatc cgaaaaatat catttttcat atagctatct
     7321 ctcagccatc tttactgaaa aatttggtat caacttttca aaatatctaa aaaaagtccg
     7381 tatcagtaaa gccaagctct ttttgacgga aacacggctt actttgacgg aaatctgtga
     7441 gaaagtcggc tataccgaac tgggttattt ctccagagtt tttaaagaag agacaggaat
     7501 gacaccttct caataccgta aaggaacttt tgtaaaatga gaaaaaaaat caaagagcat
     7561 gaactctttg ccaaacttct gttcattttg ttcatcggtc tttttctgca agccatcgtc
     7621 atttctttgt ttatttatca tcgatcaagg gatgcctata tccagctgtt caatcaatcg
     7681 aatgatgtgg tactaaaaaa gattcaatct gaatttgaaa gtttgaatga tacaatcgag
     7741 aatacattag ccgcttttga ttctaatcca gctgtcaaaa gctatttttc caatgatcca
     7801 gcccaacata tggaacagct tcagcaacta agaacaatcc aaaaaatgaa tgactctctt
     7861 tcaaaaatcc atccaatgat cgattacgat gtattgatct ttggagaaaa tggaagaact
     7921 tttgtcggaa acgacatgct cactgccgta tctgccgatt ctttttttca atctgcgatt
     7981 gctcagagag tgaatgaacg tgctgctgat acacaaatgc tttttgcaca ccacggattg
     8041 actcttcgcg ataagaaagc acccagcgtc ttctttgtca aaaaactgaa aaatacattg
     8101 aatcacgttt acggatatgc tgttttatcg atctcatcca agcaactagc gaatcttttt
     8161 caatctgtag taaatcctga gatatcgaag atctccttca tgaacgaaga acagacgatc
     8221 atcgcatcaa atgaagaaaa tacaattggg agccgatcaa tgattttcaa aaaactaaca
     8281 gtaggtgaaa caacgatttc aaatggacag cagttgaccc gtcttcctct gtaccgccag
     8341 gattgtacat tactcagtca agtcgatctt cattctttat ctaaccaaat gggcgtgatt
     8401 tttccgatta ttttgtataa tatcgtgaca cttgcttttg ctggctcatt ggtatttatg
     8461 tatttggatc gacacacaaa atcgatctac cgcttgattg attcgctaaa acggctagag
     8521 gaagatggct taaaagctac tgttcctgta caaggaagcc atgaagtcca attgctaggg
     8581 aatacgatca atcaattgct aagtaatgct cagcatcatt atgaacagac gatccaagac
     8641 gaaaagaaga aacgttcgct tgaaatccaa actatgcaag cacagataca gccccatttt
     8701 atttataata cgctgactag cttgaaattt ttgatttggc agaaaaaaac agatgaagca
     8761 gttcaaggaa tcgacagttt cattacttta ctaagaagta cgattgggaa aaaagaagaa
     8821 gtgattccag tcaaggaaga aatcaaaagc gtacaaagtt acatcgatct tttgagtatg
     8881 cgatatggcg aaagaatctc ggctaaaata atgattcctg atgaactgca gtcattatct
     8941 atgccgaata tgatccttca accaattatc gaaaacgcct atcttcatgc ttttcacaat
     9001 aaaacgcaag gattcatcac ggtgtacggc aaaacaaaaa atcagcttct tttattcgaa
     9061 gtgattgata acggcgatgg cttcgatact gaaaatacca aacaaaaaaa tgatcatttt
     9121 tcaggaatcg gcatcagcca tgtagatgag cggatacgcc taatgtatgg cgatgcatat
     9181 ggcttaacga tccaatcagt gattgggaca ggaacgactg taacgatttg tctaccgctt
     9241 cttcctaaaa atcaatcaga atatcaaaaa taaagaatag ccaagcgctg atttttttat
     9301 tttaagttaa ataaatcaat cagtattctt gactttcatc tacgcgtctc ttctactgtc
     9361 agcactggat aacagcccaa tatttgactt tctcctccga gcatcttgat ttcttggagc
     9421 gcattctcta ctaatgtcat tggacggtcc aacaacaaat cgatcacgaa aaaatattct
     9481 cccaagctag ttttcaatgg tcgggattca atcttactta agttgatttc ccgccagcca
     9541 aaagctgcca gcattttatg aagcatccct ggccgattag caggtagtgt caagatgaca
     9601 ctcattttta ctggagctga ctgctggctg gtcatctttc ggtcaccgac gatccaaaaa
     9661 cgtgtctggt tcaactcatt atcttggata ttctcagcta agatctccaa tccaacatgc
     9721 tgtgctgttt ctaatgaagc aatcgctgct gcgtcttctt tcggatgttc tgctacatac
     9781 attgctgcag cagttgttga ttctgttgct actaaaggaa cattaggata atgcgtttct
     9841 aaaaactgtt gtgattgtgc tagtgcttgt ggatgtgaaa ggatttttgt aatctttgtt
     9901 gctggattgc ctaaaagctg ctgcttgata ggaagaacga tttcactttt aacttcgact
     9961 tctggatgtt tggaaagaag atcgattgtg tgatgaacag ctccttccaa tgaattctct
    10021 acaggaacga cagccagatc gacttgtttg cgaaacaaag cgcgcaaaca aacagggatg
    10081 gaagcatacg cagtcaattg ttctgtagga aatagctgac aagccgcctg ataagtgaat
    10141 gaactttctg gccctagata gctgacgttc atatgctttt gatcctttct ataatggtat
    10201 cgatgatctt ttctggtgtt tgattggtcg tgttgattcg atgtgtcgca ctttcttcat
    10261 accaagaaag tcgttgtgcc aataatgctt ttatttcttc tcttgttttt ccaagagcta
    10321 aaggtcgaat agacgtttca tcttgttgga tacgatcaac tagacagtcc gcttctgcct
    10381 ctaagtaaag aacaatcggc tgtgttttta aaaaacgccg attttctgca ctttggacaa
    10441 tccctccacc agtcgcgata attttgtctt catttgacag ctttcttaaa atatctgact
    10501 ccacttttcg aaagcttttt tcaccgtaat agtgaaaata ttcggcaatc gacaattgga
    10561 tatgttcctc aatctttgta tctaaatcta catactcttt ttgtaaacat tgagctaacc
    10621 ctttaccgat tgttgttttt ccagcgccca tgaaaccaat cagcaaaatg ctagccatga
    10681 gcttctcctc ctgacacaag ttctgctaaa tcgtcaaaaa atgccggata agagattgaa
    10741 acagcttcag ctccttctag ttcgcaaggt ccatcagcta tcaaagcagc tacttgcagc
    10801 atcataccga ttcgatgatc gcctctgctg gacacttttg cgccatgcag aggtgtcggc
    10861 ccatggatga tcagaccgtc tgctgtcgct tttatctttg ctcccatttt ctgtaattct
    10921 tctgccaccg catcaattct gttggtttct tttactttta attcttctgc gtctttgatg
    10981 atcgtgattc cttctgcttg agtagccact aaagctagaa tgggcaattc atcaatcaga
    11041 cgcggaatga tttctccacc aatcgttgct ttcttcaaat gactcgtctt gacacttaaa
    11101 tcagccgatt ggttctgttc attgtgattc gtctgggtaa tcgctgcgcc catctcctcc
    11161 aacacatcta agataccagt tcttgttgga ttgaccccga cattttttaa caacagttgg
    11221 ctttccggaa caagaagtcc tgctgctaga aagaaagcag ctgatgaaat atcacctgga
    11281 acagttatct gttgaccagt taatttttgc ggtccggtca ctatgatcgt tttatcttcc
    11341 actgtgatcc ttccgccaaa ttgacgaatc atttcttccg tatggttacg ggaacgttct
    11401 ttttcaacga ttacggatgt gccttctgct tgtaatgccg caaacagcaa agcagatttg
    11461 acttgcgcac tggctacagg catattgtat cggataggtg ataaagagcg ggttcctgtc
    11521 acagtgattg gtagatactg gtcattttct tctccttgca agtcagcgcc catctcgcgt
    11581 aaaggttcca tcactcgccc cattggacgt ttagacaacg aagcatcccc gaacagagta
    11641 gtcgtaaaag gctgtccagc caaaataccc atcaataaac gtatggtcgt accggagttt
    11701 cccatgtcaa ttgattcggt tggttggaca aatgagtggc taccgcgacc atgaatcttg
    11761 atcacctctt cctcttcttc gatctcgaca cctaattgtt ggaaggcatg taaagtactc
    11821 agacaatctt ctgcgcgcaa aaaattttgt atagtcgtcg ttccttcagc aattgctcca
    11881 aacatgatgc tgcgatggga aattgattta tctgctggta tcctaacagt ccctcttaat
    11941 ccatgtattt gttgtaataa ttgcatttat ccagcctcct atttgatcca gcaatgataa
    12001 ctggtattag acataatgat tctttttgct tgtaacaaat cctgttggtt tttaaaactg
    12061 atttgcagta ttcctaaaat atcttccctg gtctcttgga tcttcaaatt aatcaaagaa
    12121 actcccgctt ttccgatcag tccagttact tctgcaataa cgccaggttc atctggcaca
    12181 tcgataaata aatcaaaaaa ggcaggaatc gcgccttgct tatggacagg caactggtct
    12241 cgactttctt ttgcccgatt gaaaaaagaa aagatttccg attggttctc agtcatgatc
    12301 cattctgcta tttgtgtcat ttcttgttgc caatctgcca atcgttccaa taatatctgc
    12361 ttattgctca acaaaatatc tgtccacatg acaggatctg aggaagcgat cctagtgata
    12421 tctcgaaagc ctcctgctgc cagttgtttg gctcgcggat actcttgatt gaattgttct
    12481 gcctgattga ctaagccagc tgccagaata tgtggaaaat gacttagcat tcctgttata
    12541 cggtcatgtt ctcttgctgt aagagttaca tattttgctt tggttccgca aaatagttct
    12601 tgcagttttt caacatcttt tttcgtcttt tccaaaggtg taaagatgta ataggcattt
    12661 tcaaatagtt tagcatctgc tgcctgtata cctgatttat gagaaccagc cattggatgt
    12721 ccaccgacaa accgaagatt tttctgctca gcggatgtca cgacttgctg cttcgtactg
    12781 ctgacatccg taatgatgac gtgatcagac aagttgattc tttcaaggac atcaagataa
    12841 gctaaggttg tacggacggg aacggctaat aagataacgt ctgcttgttc tgcacctgtt
    12901 tcaaaatcac ttgcaacgta atcaacgatc tgctgttcta ctgcttgctc acgggttttt
    12961 gactgactat cccaaccaac tactatcagt tctggattgg tctgacgaat acaaagtgcc
    13021 atagaagcac caatcagtcc aagccccacg ataaaaacat gttgtgccat cttatttgcc
    13081 ccctttttag taatgtttca agtagtcacg gtactccttc actgcagctt tcaactcaac
    13141 aagcgaatca cttgggaatt ttgacaatag ctctgtcgct accacagtgg ctacaacatt
    13201 ttccgcaacg acgctagctg caggaactgc tgtactatcc gaacgttcta cacttgcttt
    13261 gtaaggttct tttgtatcga tatcaacact ttgaagtggc ttgtacaatg taggaatggg
    13321 tttcatgacc ccgcgaatga caagtggttc gccattggtc attccgcctt cgaagccgcc
    13381 tagattattg gtacgtcgga aatagcctct ttcttcttcc cataggatct catccatcac
    13441 ttctgagcct ggtaatgaac cagaagtgaa tccgacccca aattctacgc ctttaaaggc
    13501 attgatacta accacagctt gtgcgatttt ggcatctagc ttcgtgtccc attgtacgta
    13561 gcttcctaat ccagctggaa cgcctccaac gagcacttct acaattcctc cgatcgtatc
    13621 tccatttttc tttgtctgat cgatcaaatc ttttattctt tgctcaactg ctggatcaac
    13681 aactcgtact tctgacgctt cagaaatttc tttgatttct tgaatcgaga tatttccagg
    13741 tatttctgct tggattccac caagacaaat cacgtgtcct gctacgatga tgtcaagttc
    13801 ttccagaatt ttcttggcaa ttgcgccgat tgctacacgc atggtcgtct ctcttgcaga
    13861 ggaccgttca agcacattcc gaagatctcg atgatggtat ttcataccgc ctaccaaatc
    13921 cgcgtgtcct ggacgcggac gtgcaactcg ccgcagtgat tggtcttttt caggcacttc
    13981 tgctacagac atgacagttg tccaattttt ccaatcttta ttttctacca ctaaagtgac
    14041 aggtgaacca attgttttgc cgtgacggat gccagacgtg atccgaacac gatctttttc
    14101 gatcttcatc cttcctcctc tgccgtaacc agcttgtctg cgagcgagtt cgtgattgat
    14161 ttcttcttct gacagaggta atcctgctgg tagtccttca ataatggctg ttaattctgg
    14221 tccatgggat tctcccgcag tcatataacg catcttacag tcctcctaag taatctttga
    14281 atgtctctgt gggaacagga acgatttttg cttgcccaat cttttctagc aagatgatat
    14341 tcaattggct tcctcttgct ttcttatcat gggttatcgc gtggaataat tcatctggat
    14401 gacttagatc gtacgtaatc ggcagatgga atttttgaag tatcctttct aaagcagctg
    14461 tcgatccagt tggagacaag ccgatttttt ctgcatgaga agtgatggct accattccaa
    14521 tagctactcc ttctccatga ctgactaccc catatcctgc tgtattttca attgcatggc
    14581 caattgtatg accaaaattt aaaataagtc gatttccttg gtcaaagaca tcttcttcca
    14641 ctacttttcg tttgatttcc aacgtagcag taatgattgg aacagcatgt tccagaagat
    14701 ctttttcgtc tttcagctcg ttcagctgtt tccaaagcgt tgcatctgct atagctgctg
    14761 atttgatgat ttcagcgatt ccttctcgta aacgacgtac cggcaaagtt tttagaacct
    14821 caggatcaat caatacacca gctggctggc taaatgttcc gacaaggttt ttcgctttgt
    14881 ttgtattgac tgctgtcttc ccgccaatac tagaatctac ttgtgcaagt agcgtagtcg
    14941 gaatttgaac gaaatggatc ccacgcatga acgtcgaggc cacgaatgct gctagatcac
    15001 ccaccattcc tccaccaagt gcaagtatcc catcgctgcg ggtaaaatca ttatctgcta
    15061 aaaaatcgta taactcagct gcttgttcta aagatttact ggtctcaccc gccggtacga
    15121 ttgaaaggac tggttcaaaa ttagcttgtc tcaattggaa catgattttt tctgcatata
    15181 gtggagcaac gtttgtatca gtgatcacag ctactttttg aggtctccaa atcgtttgaa
    15241 gccatgatcc agcctgttct agtgcgcctt tttcaatatg aatatcgtat ttttggttat
    15301 caacatgtac agtaagcatt cgtttcactt ctttctttta aaaagctgga attaatcgag
    15361 tgtctgaatc ttttccattg cttctttcat gatcgcaact tctttcatca tgcgtgagta
    15421 agtcttttca ttcaacgatt ggggaccgtc tgaccaagca tttgcaggat caggatggat
    15481 ctctacgatc atgccatctg ctccgcttgc cacacccgca cgagccattg gtggtacaag
    15541 ttcccaaatt cctgtaccat gacttggatc aacaatcaca gggaaatgag ttaatttttt
    15601 catcaatggg acagcactta aatcaaacgt attacgtgtc gctgtttcgt aagtccgaat
    15661 cccacgttcg ataaaaatga caggagattt gtcttcgact gcaatgtatt ctgcagcatt
    15721 aagccattca ttgatcgtac cggaaattcc acgtttcaat ccaacaggtt tacctgtttt
    15781 accgacagca gatagcagtt taaaattttg catattacgt gcgccaatct gtaggatatc
    15841 gctgtactca gccaccatat cgatatgccc ttcatccatc acttcagtaa tcactttcat
    15901 tccaaattca tcagccgctt gacggatgta tttcaatcct tcttcttcta aaccttggaa
    15961 agcatatgga gaagtacgtg gtttgaaggc accacctcgc agaatttttg cgcccccggc
    16021 tttggccatt cgcgcacatt ctctgatttg gtctaatcct tcgatagaac aaggaccagc
    16081 catcgtcacg aaactgccgt caccaatttt tactccgtct acatccacga ctgtattgcc
    16141 aggatggaat tctcgagaag tcaatttgta tgtgtttaaa atacgcacag cattttctac
    16201 tccttcatag cgtgtaaatg ctccttcttg taaacttcgc gtatcacctt ttagtccaat
    16261 cactactcgt tctgttcctt gatcgattga gactttgaat ccttcttttt cgatatgatc
    16321 gacgactttt tttatttgtt cttccgttgc ttcttttttc ataattacta tcattgtttt
    16381 tcccgctttc ttttgtttac ttatctatct tggctgattt tctctacttt ttcaaggtgg
    16441 ttttacatta attcctacta aatgaccgtg tcctgttgtt ctcattttcg ctccttcttt
    16501 cctacttatg acccagataa tcaacaaaaa aagatgtccc tgtaggaaat tgcctctaca
    16561 gtgaacatct tcaacgagcc ttaaaaagcg ctgcaaaaat ataaaatagc cactatagat
    16621 gaatttctct acgtggctgt aagtcgtgtt taaaaatctt tagccatcat agatacaaac
    16681 ctggtttgtt tgtacccacg aagtcatgaa tacaaaccta tctaaaatag ctaaagtaat
    16741 acgtattcag ttttgtaagt tttctagatt tcataaaaaa tcgctccaaa ctgatgtaag
    16801 aattgtacct agtatagaca taaaaaaatc gactgtcaat catttttatg aaactttttt
    16861 taattttctg atagttaact ttgtttttca gaaaaataac aattggtttt attgaagaaa
    16921 atagtcatga acaaaagtat ctgagaactt ttttactctc ttgttcatga catatagaat
    16981 aaagcagctt tgtcttgtaa actccgtttt tcaaataata atctaaagat tgctactgaa
    17041 taataaagcc gatttcatgg tcctcttcgc tgctgattcg gtaaggtgac tcaacatccg
    17101 ctccccagct attgataccc ccgactcctc ttacttttgc aaaaatcgta agaaccgttc
    17161 gtctttctgg cggtagttct tctatatgtg ttgcctgttc cagttcttct gctttgaatg
    17221 gtaaagcgga aaaagcaaat ggcgtatcct gctgttcaaa tcgcaacgaa aaatcttctt
    17281 gatctttatc cgtattatcc aacgtttgat ttcttgttag ttctacccat ttcgtttcca
    17341 tatgcatgcc gcattcttgg ggaacaaggt atggggaaac ggggagtcct gccactttat
    17401 aaataccttc gacaccacca gccatccgat ccggatatgt ttcccctgat aggccttcat
    17461 actcaaaaaa ttttgctttc gttggcataa tgaaccttaa acccaatgcg ggtaattccg
    17521 gtaatccttt ttgtccataa taatgcatat tgacaagcat tttaccctct ccagcgattt
    17581 ggtaggaaat tgtcacttgg gtttttggta ctgtgttgat ttccagtgta aaaatgattt
    17641 caaccgtttc agcgtattca ttacttgaat attgattatt tactggagca atcggcaaat
    17701 cgatcttttt attgtccacc agtacttcta tttctttgac ttttggatac aatccggctc
    17761 ctaaccacat accggattta aatccaaatc cgctacctct gtcattatcg gtcgttgctc
    17821 gccaaaaaac tggaagtgtt tcccggtata gccattcttt tccgttttta ttgagcgatt
    17881 ccagtccgcc tcttgtataa gaaaaaatat aatgcgtatt ccccgatttg acacctaatg
    17941 tacagtcgcc gaagacgatt gcaacttttt ccgtatccat atgactttta tttactgtat
    18001 ttttcataat aatatcttac ctcctgcatg gcgggttttt cttgtccatc tgcaaaaacg
    18061 atcccattcc ctgagaattc atagtcactt ggtttatcgt caaagtcacc gccatagcgc
    18121 atcacttctc tgcctgtgat tggatcagtc acttggatcg cctgatcttt aaaatcccat
    18181 atatagcctc cttggtacat ttcataacga tcaagcaacg tcatgtaaga atccattcca
    18241 cctaacgaat tccccatgtc atgcatatat tcacataaga tgaacggttt ttccgcttta
    18301 ttttcaaggt agtcaatgat ctcttctggt ggcgcataca tgcagctttt tacatctgaa
    18361 atcgaatctt cgaatgctgg atttggaaaa ttcccttcat aatggacaag tcgatcgggg
    18421 tctacttttt tgaagtaatc gttcatttgt cgaatgtttt cttccgcata agattcattt
    18481 ccaagagacc aaaaaagaat acttggatgg ttttttaatg tttcgaaatt cgtttttgct
    18541 cgatcaagaa cagccgcctg ccactgaggt actgcacctg gtacgttgta agaaggctca
    18601 aatgcgccca ttttttgcca tgagccatgg gattcgaggt tcgtttccgc catcacatgg
    18661 attcctgctt ggtcgcataa ataataccaa gtgatctggt tggggtaatg agatgtccgt
    18721 acgccgttga tctttgcatt ttttatgata gccaaatctt tttccatatc ttctatagtg
    18781 atggcgcgtc cttttttcgg atgccactca tgtcgattta ccccgttgat aatcatccgt
    18841 tttccattga agtagatgat tttatctttg atttcgattt tacgaaaacc gaaggaatag
    18901 tcaatatact ccgttactct tttttcttcg tctatcgtct ccaattcaag cttatataaa
    18961 ttgggctgaa aatgccccca cagtgccaca ttttcaaatc catcgatgcg aatcgtcatt
    19021 tgctctttta acggatattg ctgttgatag atttccttcc catcaggatc tagtatcgct
    19081 acattcagct gactgttttt ggctacttgc tcaaaagaca aatctacttc aagtttgcca
    19141 ttttgacatt tgtcatctaa gcgaggtttg atccaaagat cttctaaatg gttttgtcct
    19201 cgagcaacta agaagacatc tctgaagatc ccaaaaaatc ggaaaaagtc ctgatcttcc
    19261 aagaatgcag ctgtacttct tttgtaaacc tccacagcta gaatattttc ttcttccaaa
    19321 taaggtgtta aatcaaattc agacggagtg aacgaatctt cggcataccc gataaaatga
    19381 ccattcaacc aaataaacat tgcttgttct acaccagcaa aatgaatcga gatttgtttt
    19441 ccctttagac cttcttctaa tcgaaaagtc gtcaaatacg aaccaaccgg attgtcttta
    19501 gcagctgaaa agatcccttc cgcctctttc tcagggcttg tcgtgaaagg gggacggcga
    19561 aatacatgtc cctcccacgg atacatcgta ttgatgtaat ggatcttgtc ataatttgct
    19621 aattcaatat gactaggaac agtgatttca tcaaaagaac aggcatcaaa atctttttta
    19681 taaaatgttt ttggtcgtac cgaaggattt ggcgaataac aaaaacgcca tgatccattt
    19741 aaagactgtt taagggagga tgtggtttct acttcttccc ttgttgcata acaaacatga
    19801 tcgctatgtg catttgattg gttcactcta aaaacttgtg gatcatctaa ccattttata
    19861 tttgctttca tacttttttc cttctctctc ataacttttt gaaatgaagc agttctgttt
    19921 ggaaatcacc ttgaaaatcg gggaagtaaa gtccaactgt catcaattcg gcccccgaaa
    19981 atatccgctt cgaggtctgt tcctgataaa gtgcctcatc atctaacccc atcagatata
    20041 cttcatggaa cgctggttga gctgaagcta gtatcctccc taaaaacaca atagcttcat
    20101 cttgtttagg agacacaaac atccatgcgg caatattttc ttcaaaagga ctcgccaaac
    20161 gataataatg gccatactgg atcaccggac gaatcgtttg ataggatata atttggtctt
    20221 ttacttgctt ttcttcttca ggagacagct ttgtcaaatc cagttcataa ccaaaaacag
    20281 cgctcatagc tgtttctcct cttgttttca acgaagtaga tctgtcggtc tgatgatttg
    20341 gtacagctga tacatgagct gtgatggacg aaatcggata agcaaggctt gttccatatt
    20401 ggattttcat acgctccact gcatccgtgt tatcacttgt ccatgactgc ggcatataat
    20461 aaataaaccc ggcatcaaac cgtccacctc caccagaaca gccttcccat aagatttccg
    20521 gataatcagt tgtcaaatgt tcaagtagtt cataaagccc gagcatataa cgatgcgcta
    20581 cttctccttg tctctgtggg tcaagggtaa tcgaatagac atctgaaagc gaacggttca
    20641 tatcccattt gatgtagtca agaggaatcg tatctaaaat ctttctcatt tgtttctcaa
    20701 tcgtctgccg aacatctaac cttgtaaaat ccagtacatg ttgtgatctg gaagcagaag
    20761 gcattctacc tggctcctgc ataagaaaat caggatgtgt tcgatacagt tcagaatcaa
    20821 ccgagatcat ttcaggttca aaccataaac caaatttcaa tcctttgcta tgagcataat
    20881 ctgctatttc acgtaatcca tttgtcaact tgccttcata ctcgaaccag tctcctaatg
    20941 aagaattgtc cgcatctctt tttccaaacc agccatcatc taatacgaac atttcgatgc
    21001 ctagctcctt tgcttcatca atgatcgcct tgattttttc actattgaag tcaaagtaag
    21061 tggcttccca gttattgacc agaatcggcc gttcagcaaa ttgatgacga cctcttgcga
    21121 ttctttcacg tagcaactca tggtggatct gactcatttt gttcaatccc tgacttgagt
    21181 aagaaaggat catttcaggt gtttgaaaag actggcctgc attcaattcc cacgaaaaac
    21241 gatggctgtt gatcccaccg acgactctca attgattgat ctgatctttt tcaagttcga
    21301 aagaatggtt gccggaataa acaaattgaa gtccgatcgc ttctccagta ttttctgtcg
    21361 tatgatgatg aactaaagca ataaagttat tcatatggtg actgctcgtt cctcgacggc
    21421 tttcaaatac ttttgttcca gataaaacag attgccgtga aatctgtctt tcattgacat
    21481 gtgctcctgg caaagcaatg acttcatcaa atcgcctagt atgggcaaag tctagctgga
    21541 aactagccgc tttttctagt ttgattgttt ctccggtttc atttcttatc tttacagatc
    21601 gtgtgatcac tgctctatca gtaaatatgg tatagaacaa atcgaaataa atcgctgttt
    21661 ctctatcctt aagtgaaatc accaacgttt gtgcctctga cttgtccatc acataagttt
    21721 gaggcaagcc ttcgatctct ggcttcccat ctgtaatata atggctgtca tatctcagat
    21781 ccagtaagtc tgatccattc ttgcgctgaa tgatcgatgc gggcgttcga aagtccatgc
    21841 tgccatgaga agagtattct tgcggtagtg tatctttcga cagagaccgg tcaggattta
    21901 agggaacatt tcctgaaaat ccacgatctc ttcggggata atttttattg tctttgtact
    21961 gcttgactgg tttgccaaaa taaatatgcg ccaatacatt gctttcttct atctttatca
    22021 gataagaaag aaatgtattt cgtaaatgga agactcggct cttttcatca aataagatga
    22081 aatttttatc tgtttttcta tgcgtaatat ccatcatttc actcccaaca aaacggaaac
    22141 cgtttacttt tttttataat tcctgtatac tgtttactaa acaattttgt caataaaaat
    22201 tttttatttt tttgaggagt gtgtaaaaat ggttggaatt agagatgtcg cacgaaaggc
    22261 aaatgtctct cctgctacag tttcccgtgt gttgaataac gatcagacga tccatgtggc
    22321 tcagactact cggcaacgga tagtagaggc agctgctgcg ttggattatg acatcagtac
    22381 tcgtaaatat atcaaaaaga gaatgccttc gattggtgtg atctctacga tcggcaaagc
    22441 gagcgaagaa caggatatct attacaaaca tttgcgagta gggatggaag aagaagctcg
    22501 acgtctgcat ttagggatga atcgaatcta taatctatct gataatccta aacaatggga
    22561 agatctagat cagttaggtg cggtgatcgt tgttgggact gttacgaaag aatcgattac
    22621 cgccttgtta aaacaaaaca tgcaaatagt cgtcgtggat aaccctgaca tccagcaaga
    22681 ggtcgatatg gtgtatgcag atcttgaacg gatgactaaa accgtactgg aattgttctt
    22741 agaaaatggt cataaaagaa tagcctatat cgggggatat aaagtcgata tggatgaatt
    22801 cggtgggaag cagatttcta taaatgaaaa gaggatgcgt gcctatcagc attttatgat
    22861 cgatcatcac ttagaaaaat atatgtctta tcatctaggt ggctggacag aaaaacaagg
    22921 tgaggtactt gcgactaatc tattagaaaa tgaatcccct cttcctactg ccattcttgt
    22981 cgggagcgat ccaatggcaa ttggtgtcta tcgggcattg aaacaaaaaa atatccaaat
    23041 tggagaagag attgttgtag caagctttga taatatcgag acaatcgcaa acctctcccc
    23101 tggcttgacc agtgttcaaa tcaatgcgaa atcaattggg caagcagctg ttcgaatggc
    23161 attggagcga attgacggta tacgggacga accaatcatt ttgacttatc ctgcacgatt
    23221 gattgttagg gaaagtttta tcccaagaac aaaaaggtat tgaaagagag gttgtgaaaa
    23281 gccgcttcgt ttcttcatac tcaaaacgaa acggcttttt cacaacctct tacttatact
    23341 tattcacaaa atccaatgtc tgctggtaac aattttgcga ttcttttagc gtgtaatcaa
    23401 attggtattc atgggtaatc tctttttttg tatctgtata aaacaaggat tgcacgggta
    23461 cctttaattc tgtcaaccga ttttctaatg cttgaccttg ctcctggaat gagtatgcat
    23521 ttccgtcagt tatatacgtt ggcggaaatt ccttagaaac atggtcagcc acactagctt
    23581 ctttcaattg ctcactcgtt ttccaatctt ttgttccaat caacgaccac gcaacggttt
    23641 tgacgaaaaa cttcataaat cgatcatccg aatgctgctg tgctgttagc ttcaaatcaa
    23701 caggtccgca ataagaaatg gttcctttca gactatcttt tggaagtagc tgtttgattt
    23761 tcatttgttt agcatacgca tcattcgttt gtatagctgc atattgcaat gcgatttgtg
    23821 aacctgcact atctccacca aaaaataatt gttccatgtc tagcaatttg tcgtcttttt
    23881 cttcagctaa taaatctttg atcagttcat tcacttgaag aacttgatta gggtattctg
    23941 aatcaggcgc taattcataa ttcatcgcaa ccactgcgat gttggcgtct gaaactaatt
    24001 ttgtcgcaaa ttctttgaca cccgatttat ctccgccgac gaatcctcca ccatgtaccc
    24061 aaaatagaac aggaacaggc cccttgctgt tttttggata gtagatgtca taagtattct
    24121 ctttatactt ggactcatac gtcaaatctg tttttttcgc cacgtttttt tctgcttgat
    24181 cgaacgtttt tttatcagtg atttgaacag tatttgaaaa catatggttg atcaagaatg
    24241 ctccaggtct gggggaaagc tggaaggcaa gaaagattgc aaacgcgatc ccaagaatga
    24301 ttccgaagaa ccatccgata aatttaagaa ttttcttttt cataaggctc cctcagtagt
    24361 tagtattaag cattctgatt ataccatagt gttatttcct atcaagctct cctagatgat
    24421 ttaatgattt tccccaaact tcttctgcaa tgcttttgac aaaagaaatt ttttccattg
    24481 ttcttcaaac aaaacatttt cttcttctgt tgaagcaaat ccacattgag gacttaagca
    24541 caaacgatcc aaaggcagat atcgtgtcgc ttcgtagatc cggtcaatca cttgctggtg
    24601 ctcttccatt tcgccatttt tcgttacagt caaaatctaa gacaactaat ttatcttcag
    24661 agactttctc taaaagaaca aaactcccag cacgttcact atcgtattct aaataatagg
    24721 cacggacatt ttcttgagta aaataatggg tctgctacgt cgtcatcccc cctgatgccg
    24781 ccaaaatcga ataataattt ccgcgtcaaa catgtatatt tagtgttgaa tcatttgaga
    24841 atatgaaaat aaaaatcttt ttgatcaatc agttaatcaa attgaaataa cgaaaaatct
    24901 gagacagaat gacgttcatt ctgacccaga tttgattttg cacaactcaa cagtccttat
    24961 tggcaaatcg ccaaaataat gtagactaac taaaaagact aagaaacaat aacaaaagtt
    25021 aacacttctt agtctttctt tagcacgtct atttattaaa gattttaggg ccttttctca
    25081 tgtttttacg atcattctta ggtgtttcca tttgtttgga tcggcctcca ccttgtttct
    25141 ttttgatcaa ttctttcatt ttttcttttt ggtccatttt tattctcctt taacgaatga
    25201 agcgactaat tcgatatgat gggtttgcgg gaaaagatct acaggctgaa ctttcttcac
    25261 ggcataacct gcttctgcaa ataacttagc atctcttgca aaagttgccg gattacatga
    25321 gatatagacg attcgttctg gtgacatttc gattgctgat tcaataaaat gatgatctaa
    25381 tccttttcgt ggagggtcaa ctacgatcac agatggtttg atcccttttt cttgccattt
    25441 tttcataact ttttctgctt ttccgacttc ataatgaaca ttttcgattt tattatttaa
    25501 agcattgaac tgtgcatctt caattgcttc tggaataact tccatcccat acaccttatc
    25561 cactctgtct gctaaagaca agccaatcgt acctattcct gaataagcgt cgatcacaat
    25621 gtctttttta tctaactcgg caaactcgat ggctgtttgg tacagatact ctgcttgttg
    25681 agtatttact tgataaaatg actttgctga gattcgatag gtttttccta atagctgatc
    25741 ttcgatatag tctctgccat ataaaacttt ttctttgtct cctaaaatca catttgtttt
    25801 ttcttcattg atattttgga tgaccgaaac cacttctggc aattcttcat gaatagcttc
    25861 agcaatttcc ttggatttaa agaatttttc tttacgagta actaaaacga ccatcatttc
    25921 atgggaataa tgaccacgac ggataatgat gtgacgaagc tgtccttcat ttttttcttc
    25981 attatatcct cgtacttgga accgttgcaa gatatctctg actactttga ttgcttgatc
    26041 gatgacagga tcttggatat aaaaatcttc gatagggact agatcatggc tattcttttt
    26101 gtaaaaaccg gtggctaact gtccatcgat acggcgaaca gggatctgtg ctttattacg
    26161 gtagccgaat ggttctgcca ttccgaccgt tggaagtaca ggaacttctg gcatcttagc
    26221 aatcttcgcc attacatgct ctacttgttt ttgtttgaag acaagctgtt gttcatactt
    26281 caaatgggct aaaggtgcga tacctatgcg aagtaatgca ttgttttcta caggctgacg
    26341 atcaggtgat tgtgtaataa atgtttcgac ttttccatat ccaaacttat tgcctgcttt
    26401 tactactagt atttctactt cttctccagg gagtgcattt tcgataaata atggataacc
    26461 atcgattttt gctaccccca ttccttcata actcaagtcg acgatttcga ctgtatatcg
    26521 ttcgtttttc tttactattt gctgttctgt catattttgc tcctttaagc ctatttttca
    26581 atcctactga actctactat aaatcagcta attacacaac taaaaccggc actgacctta
    26641 ctacgttcag caccggcttt tgattaattc ttttgattag gtgtttcgtc tgctattttt
    26701 ccgtcaccgt cgatatcttc atccgttaaa cgttcgactt cttttacgaa ttctttgctg
    26761 acaacctcta attcttcttc atctgtacct gtgattgctt catcaggaat ctgatcggta
    26821 ttggcaaaga actcaatgtg ttgatgaaga ttttggaaat gcatcggtgc ttccccgccg
    26881 tattcaccat ctaagttgat cattactggt cgattgatat catcttctgt ttcaacgaac
    26941 aaactgcttg ttttggtata gattattctt ggatcatcga catgtcgacc gccattcagc
    27001 atgagtgctg caatatgcaa gatctcaaag atatttgctg tcttcacaat gattaaagaa
    27061 aacttcccat catccaattt ggcatctggc gcgatctgtt cgaatcctcc aacagagttc
    27121 gtcagcccta ggaaaaacat cgaagcattt ccgatatatt ccccttcatc atacttcaag
    27181 cgcattttga ttggctttac tcgagggagc atctctgctc ctttcgcaag ataagcaaga
    27241 taaccaaaaa tactctttag ttctgatgga acttcataag tcaattctgt caaatagcca
    27301 cctgcagcga tattgatgaa gtaactgtta tcagaaaggc cgatgtccat ttttacggtt
    27361 tggtgttttt ttatcacttc tgctgctgct ttaatattat ctctaggaat ttttaatgct
    27421 cgagcatagt cgttcgttgt accagctggg atgatggcca ttttaggacg gtgttcaagc
    27481 ggagcgattc cattaaccac ttcgttgatt gtgccatcgc caccagctgc cactactaga
    27541 tcaaaaccta gttctgcgac tctacatgct tcattcttgg ctgaatctgg ttctggtgta
    27601 gttgcatagg cgctggcttc aaatcctgct tcttctaatg cctgtaggat atccgccaaa
    27661 ttttttttca ataattcttt tcccgaggtg gggttataaa ttacgcgtgc ttttttcatt
    27721 ttcagcctct atcgtttcgc taattcatct ttaagtagct tattcacgac accaggattt
    27781 gcttgtcctt tagttgcttt catgatttga ccgactagga agccaaccgc acgatctttt
    27841 ccatttttga aatcatcgac agattgttgg ttgttatcca aaatttcatt aatgattggc
    27901 agtagtttgt tcggatcaga taattgcacc caaccatttt tttcaactac ttcttgggct
    27961 tctccgccat ttgtgatcaa ttcacggaag acttttttgg cgatttttga gctgatcgtt
    28021 ccatcggcga tcaaacgaat cattcctgct aagttctcag gtgtcaattt tgtctcagct
    28081 aattccagtt tctcactgtt caagtaagca gaaacttcac ccatcaacca gttagatgct
    28141 tgcttggcat ctgcaccatt ttccaaaaca gcttcaaaaa aatcagacat ttcttttgta
    28201 agtgtcaata ccattgcgtc atactctgga agtccaaact cacggatata gcgttcgcga
    28261 cgagaagctg gcatctcagg caaactagct tttacttttt gaatccattc gtcatcgatc
    28321 acgaatttcg ggatatcagg ctctgggaag taacgataat cactagaccc ttctttgaca
    28381 cgcatcaaaa ctgttttatt cgttgtttcg tcaaaacggc gtgtttcttg ttggatttct
    28441 cctcctgaaa gaagaacttt tgcttgacgt ttttcttcaa aagctaaacc ttttttcacg
    28501 aaagataaag agttcaagtt tttcaattct gctttcgtac cgaactcttc ttgtccataa
    28561 gggcgaagag aaatattggc atcacagcgc atagagcctt cttccatttt cacatcgctg
    28621 acttctgtaa attggataat tgatcgcaat gcttctagat aagcgtatgc ttcttctggt
    28681 gaacgcatat cagcttcaga aacgatttcg atcaaaggcg tgccttgtcg gttcaaatca
    28741 acgtaagaat aaccgccaat accatgcatg ttttttccag catcttcttc taaatggaca
    28801 cgttcgatcc ggattttttt ctttttacct tctacttcga tttcgatcca tccgtcatga
    28861 ccgattggtt gatcaaattg ggaaatttga tatgcttttg gattatctgg gtaaaagtaa
    28921 tttttccggt caaaatgagt atctttagag atttcacagt ttaatgccaa agctgctttc
    28981 atcccgaatt ccagcgcagc tttattcatt actggcagca cgcctggata accccagtcg
    29041 atcacgtttg tattgctgtt tggttctgca ccaaaatgag ctggcgctgg agagaaaatt
    29101 tttgagttgg tttttaactc gacgtggact tctagtccaa tgactgtttc aaaattcatt
    29161 cgtctttccc tcctaaaata gctggttgtt gtttatggaa ttctgttgct tgttcaaacg
    29221 catatgccgc ttgatacatc gttttttcat caaaataatt accgatgatc tgcaatccaa
    29281 ctggtaatcc ttctgataaa cctgccggta cagacatacc tggaagtcca gccaagttga
    29341 cagggatcgt taagatgtca ctcatgtaca ttgtgattgg atcgttaatg ttctcaccga
    29401 ttccgaatgc aactgttggt gaagatggcc cgatgatcaa gtcataatct gcaaagactt
    29461 tttcaaaatc tcgtttgatc aatgtacgga cttgtcctgc ttttttgaag taagcgtcat
    29521 aataacccgc gcttaaggag aatgtaccta acatgatacg gcgttttact tcttcaccga
    29581 atccttctga acgtgagttg acatatacat catctaatga tttcacattt tcagagcgat
    29641 aaccgtagcg gataccatcg aatcgttgca aattggaact tgcttctgat gaggcaatga
    29701 tataataaac agccacaccg tattttgaat gaggcaagct gacttcttcc acaacagcac
    29761 ctaatgaacg gaatgtttct gctgctttca atacagcttc ttttacgcca ggggccacac
    29821 cttcgcctaa gtattcttta ggtaaagcaa tcttcattcc tttgatgtcg cctgtcagtc
    29881 cctctgcaaa atcaggaact gaaacgcctg aagaagtacc gtctttttcg tcataaccgc
    29941 tgatagctgt caatgctaat gcattatctt tcaccgtacg ggtcattggt ccgatttggt
    30001 caagagatga agcaaaggca atcaaaccaa aacgtgagac acggccataa gtaggtttca
    30061 tccctacgat gccgttaaaa gctgctggtt ggcggatact tcccccagta tcactaccta
    30121 aagaaactgg aatttgtcca gctgcaactg ctgctgcaga accaccagaa gagccaccag
    30181 gtacttttgt tgggtcccaa gcattttttg ttttcttgaa ataagaagtt tctgtacttc
    30241 cacccatagc aaattcatcc atgtttagct taccaacagg gatcatatct gcttgataga
    30301 ttttatccat gaccgttgca tcataaattg gttcaaaatt gtaaaggatc ttagatgcag
    30361 cggttgtcaa gatatctttt gttacgatat tatccttgat accaattgga ataccagcaa
    30421 ggacgttgct ttcatcaatc cctttttcat ctaaagcttt tgcctgttcc aatgcttttt
    30481 cttcgttcaa tgtaatgaat gcctcgacct caggctctgt ttctttgatt cgttcaaatg
    30541 ttgtttttgt caaatcttgt acagtgattt ctttcgatac aagcatatga tgcagttctt
    30601 ctagagaacg attgtgtaat tctgtcatta tgcgccagcc tccccattat cgatgattgc
    30661 gggtactttg ataaagccgt cttctgtttc cggcacattt ttcaataatt catcgcggtt
    30721 ccatccagct tgcgcccgat cttgtcgcat cacgtttact gtttcaacca cattcgacgt
    30781 aaatggaaca ccttccgtat ctacttcttc cagcatttca accatatcga tgattttacc
    30841 taattggtcg gtaaaacttg caagttcttc atctgcgaac gcaagttttg ctaatttggc
    30901 aacgtgtttc acttgttctt cactaatcgc catactaccc cttctttcta aacgagttaa
    30961 aaactttgct ctctatttta acacaagagt gccgtgtctg aaattgttta ttgaaatttg
    31021 tctgaaaaaa ctcatttttc attcttctac tgagcgactt ttagccaatg catctgccat
    31081 ttgatcttct gtccaaactt cgattcctaa ttcttgtgct ttggtcagct tgctgccagc
    31141 atcttctcct gctaccacga tatccgtttt tttcgatacg ctaccagtca ctttcccgcc
    31201 aagattttcg atcgtctctt ttgcttcttc acgagtaaat cgtgttagtt taccagtaag
    31261 gactactgtt ttttctttaa aaggagactc gacttcttgc aattgggcat ttcgaagccc
    31321 tttgtattcg aaattgacgc ctgcttgttt taattcattc atcaattcat ggacttcttc
    31381 gttactgaaa taagtgacta cactgtcggc aatgatatca ccgatcgtat caagcgcaat
    31441 aatcgactca tagtcacttt tactcaatgt ttctagatca ccgaaatgtt ctgctaaaat
    31501 ttttgctgct ttcgctccga catgtcggat tcctaacccg aaaatcaacc gctcgaccga
    31561 attatctttg ctgttgtcga ttgctgtcaa aatattattt gctgattttt cttttatttt
    31621 gtccaacgtc aataactctt cttctgtcaa tttgtaaaga tcagcaacat ctgctactag
    31681 ttttttatca tacatctgtt ctagtacgcg cggccccaac ccatcgatat tcatcgcatt
    31741 tcttgaaaca aagtggttca aaccttcttt catttgagca gggcatttag gattgatgca
    31801 ccgtaaggct acttcttcat ccaaatggac aagttcactt ccacaaactg gacaatgtgt
    31861 aggcaattgg tattcttcgc tgtctttagg tcgtttatct aacacgactt gcgaaacttc
    31921 tgggatgatg tctcccgctt tataaatcag aactgtatct ttcaagcgga tatccttcaa
    31981 cttaatataa tcaccgttat gcaggctggc acggcttact gtcgttcctg ctactcggac
    32041 tggtgtcatg atagctgttg gcgttactac ccctgttcga ccgactgtcc attcgatgtt
    32101 ttcgattagc gtttcaactt cttctggcgg aaacttgtaa gctgctgccc atctcggtgc
    32161 tttgatagta aaaccaagtt gatcttgtag cgagaattca ttcactttga tgacgattcc
    32221 atcgatttca tagggcaaat ccacacgttt gtcatgatat tcttcaatgt atgaccacac
    32281 ttcatcaatc gaatgacata gacgtttttc ccgattcgtg tggaatccaa ttttttctag
    32341 ctcttctagc gcatcatact gggtttttgc ttgcatagga ccgaaatcag ctactgtgta
    32401 taaaaaagtg tccagatttc ttttcgctgt gattttagaa tctaactgac gcaaagaacc
    32461 agctgcggcg ttccgaggat tcgcaaagat atcttttccc tctgcttctc tgtcttggtt
    32521 caattggaca aatgaccgtt ttggcatgaa acattcgcct cttacttcga tgttcattgg
    32581 ttcttttaat ttgattggga ccgaccggac agtttttagg ttttcagtga tgttttctcc
    32641 tacagttcca tccccgcgag tcgcacctct cacgaaattt ccatcttcat aacgcaaaga
    32701 aacggaaagt ccatctattt ttagttcaca gcaatagtca actacacgtc ccactgcttt
    32761 ttgtacacgt tgatcaaaag ctatcagctc ttctttgctg aaaacgtcgt tcaaactgta
    32821 aagcggaata tcatgagtga ctttttcaaa accttctaat acttttccgc ctactcgttg
    32881 agtgggagaa tcagacgtga tcaaatcagg atattgttcc tcgattgcta ctaattctgc
    32941 gtattcttta tcataaacat agtcttccac tgttggttta tcttctacgt agtattcgcg
    33001 agaccattgg ttcagtcttg tacgaagttc ttctgctcgt ttagcagctt cgtcaatcgt
    33061 catttcatgt tccatcattt accctccact actaagcttt ttcaattggc gcaaaggcag
    33121 ccaaaagacg ttttactcct tgacttggga aagccacatc tagttctaga tccttcgacg
    33181 tcccgcttac tcggacgact gttcctagac cccatttttt gtgtttgact ttatctccag
    33241 gtttccagct gttattttcc cctccagtag cacttttaga gggaacaacc gctgtctctg
    33301 gctgtttata gctatatgct gtttttttag cgaatacagg cgttttttta ggcgtaggac
    33361 gcatgccttc gatttccagt aactcctgat cgatttcttc tacaaaacga gaaggtcggt
    33421 tatattgcgt ccgtccatat aatgttctgg agaaagcatt tgttaaatac aacgcttctt
    33481 ctgctcgcgt gatccccaca tatgcgagac ggcgttcttc ctccagttcg ctttcttcca
    33541 tcaatgctcg agataaagga aaaaccccct cttctagacc aatcaggaat acaactggaa
    33601 attctaatcc tttggctgca tgcaaagtca tcaatgtcac ttgggaagca tcttcttcta
    33661 aattgtcaat gtcggaaaca agtgccagat catttaagaa gaccgttagt ttttcttctg
    33721 gtgcatcagc gtcttcttca ttttgctgtt cgaattgttt gtcgaattct tgtgtgaccg
    33781 ttaaaaattc ctccaagttt tcgatgcgtg cttgtgcttc taatgtattt tggattttta
    33841 agtcttctag atatccgcta cgatccaaaa cctctttcgt caattctgtc actgtcaagt
    33901 atgggatcat ctgagtgact tcttggatca tctctccaaa tgcacctaat tgctgtcctg
    33961 cttttccacc gatatttgcc agatccacat tttgcgctgc ttcaagcagt ggccattcat
    34021 gaagagaagc aaaactgcgt agtttttcga tagatcctgg tccgatgcct cgtttgggcg
    34081 aattaacgat acgctcaaaa ctgattgaat cttgaggatt taccagcaca ttcaaatacg
    34141 ctaaaatatc tttgatttct ttacgatcgt agaacttgtg ccctccaacc attttataag
    34201 gaatatttgc tttcaacaga gtttcttcca ttacacgaga ttgtgcgttc gtccggtaca
    34261 agatggcaaa gtcgccgtaa ttccgatgat tgcttcgaat ctcttcttgc atccggtcta
    34321 cgataaaacg ggtttcgtct cgttcattat ctgcacggta gtaagtgatc ttgtttcctt
    34381 ctttgttttc tgtccacaag ttttttggtt ttcgattgct attgttttca atgacttggt
    34441 ttgctgcgct aaggatgttt ttcgtggagc gatagttttg ttctagcaaa attactgcag
    34501 catctggata atctttttca aaatccaaga tgttctgcat atctgcaccg cgccagccgt
    34561 aaatactttg atctgcatct cccacgacgc acaggttcct aaatctacct gccaataaat
    34621 tgactagcgt atactgtgcg tgatttgtat cttggtactc atctacatga atataatgga
    34681 atttgttttg ataatacgtg agtgaatcag gatgttcttc aaataatcga atcgtattca
    34741 tgatcaggtc gtcaaagtcc atacattgat tatattgaag ctctttttgg taagcagcat
    34801 aacattttgc cgcaatctct tcgtaataac tgccttgcat ttttgcaaaa tcctgagggg
    34861 tctgcaggct gttttttgct tgagagattg ttcctaatat acttcgagga tcatattttt
    34921 tcggatcaat gttcagttct tttagtatcc gtttcatcaa ggtcagctgt tcagaagaat
    34981 cgatgattgt aaagttccgg ttatacccga taaaatcaac atctcttctt aaaatacgca
    35041 cacacatcga gtgaaaagtc gatacccaga catcttcgcc tccagatgcg agaatcgcat
    35101 tgacacgttc tttcatttct tttgcagcct tattggtaaa agtaatcgct aggatgttcc
    35161 aaggattgac ttctttttcc tcaatcaaat aggcaatgcg gtgtgtcagc actctcgtct
    35221 ttccacttcc tgcacctgcc attagcagta atggtccgtc agtgtgaaga acagcttctt
    35281 tctgacgggg gttcatcccg tttaataatt cagctttgga tgacattaac aacatccttt
    35341 cttttatcaa tcttgttaat tatagcattt tcttggcttt cattaaacta gctagttcaa
    35401 aatcatttgt ttctttttat ggatttttcc ttgtcaattc gttgatttcg cgctaaatta
    35461 aaagaaagcg aggcgtttga atggaaaaaa aaggaaaaat caagaaatta gataagactc
    35521 agatatattt tattctaaaa ggaatatttg ttggactgct gacaggaatc gtcgttagcc
    35581 tgtttcgatt atctatcgaa aagctaagcg atttagttcg aagtatctat gaaatgagtc
    35641 gggaacagcc gatttactta attggcctag ctatttgctg catccttgca gcatttttcg
    35701 tgggttatct ggtcaaaaat gaaccggata tcaagggaag cgggattcca caagtagtgg
    35761 gacagcttcg cggggaatta tcaatgaact ggttctctgt tttatggaaa aagttcattg
    35821 gcggtgtact ttcagttggt gcgggccttt ttctaggtag agaaggacct tctatacagc
    35881 ttggcgcatc cattggacaa ggagctggac aattgtttcg gagtccatct tcagaagaaa
    35941 agattttaat ttctagcggt gcaagtagcg gacttgcagc agcattcaat gctcctatcg
    36001 caggattact ctttgtttta gaagaaatcc atcactcctt ttctccactt gtttggctga
    36061 catcatttgc ttcagcaatc actgctaact tcgtctctct ttactttttc ggcttgagac
    36121 ctgttttata tctaggtgac cttccttctt tgccgttgaa atattatggt tccttagtga
    36181 tcttaggagt acttctaggc atcttaggtt ttatttatca gaatgtcttg ctggctttgc
    36241 caaaatttta caaccgattg cctttaccag cttattttca cgggttcgtt cctttcttgc
    36301 tgattttgcc aattggttat ttatggccta gtactctagg cggaggcaat caaatcgttt
    36361 tagcttttgg acatgcttcc ttgccaatca ttatgattat cggtttgttt gttcttcgat
    36421 tcgttttttc catgatttct tacggtgggg gtcttccagg ggggattttc cttccgatat
    36481 tgacattggg ggctttaatc ggtagctttt atggaaacat tatggttgat ttcgggatgg
    36541 atccaatcta catcaaggat tttgtcgtta ttgccatggc tggttatttc acagcgattg
    36601 gaaaagcacc gctgacagca attattttag tgacagaaat ggttggctct cttaatcatc
    36661 tgatgccttt aggattggct gctcttgttg cttatatcgt caatgacctt ctcggcggta
    36721 atccaattta cgaatcatta ttggaacgtc tacttggaaa tactcagacc gcctcactaa
    36781 aaggtgcaag gacaactttt gattttccag taacggcaga gagttcttta gacggattaa
    36841 tggtacgaga cttcaattgg cctaaaaata tgctgctaat ctctatacgc agaggaaatc
    36901 aggaaatctt gactcacggt gatacgatca tgaatgtagg agatattttg gttatcttga
    36961 ctgatgaagc aaacttgcca agaatcaagc aggaaatcga ggctaaatct tctatcacaa
    37021 atttgaagca atcattttaa cgaacatgga aaaactattt tacaacaact attcatctac
    37081 actacttgat tctatatgat tctataaaaa aagaagaggc tgggaaaacc cagcctcttc
    37141 ttttttattt ctatgcttct gctactgcag gagcttttct caataaacca taaatcacac
    37201 cagatacgac tgctccgata gcaataaaca ccaaatacat gaccgggtga ctcagtaaga
    37261 atacaacgaa aatcccgccg tgaggagcca gtaatttgat tccgaaagct ccgactaatc
    37321 cgccagttaa agcagaacca ataataaaac ttggaatggc acgaatcggg tcagctgctg
    37381 caaatggaat cgatccttcc gtgacaaacg atagtcccat cacgatgttc gtcaaaccag
    37441 catcttgatc tgttttgctg aatttattct taaacaaacg tgtagcaacg aaaattgcca
    37501 atggaggtac cattcctcca gccataacag aagccatcac gacacttccg ccagttgcaa
    37561 cagtcgtagc taaagttgct gtaccaaaca cataagcggc tttgttgatt ggaccgccta
    37621 aatctgccgc catcattcca gctaataatg caccaagtaa agcagcattc gaaccactca
    37681 tacttgtcaa gaaaccgttc aatgcatcat tgattgcttt catagggaca ttgaccagca
    37741 acatcaagaa accagtaatc agtaagccaa acactggata aaagaggatc gttttaattc
    37801 catccaatga ttttggtaag ttcttgaata atttacgtaa aaatacgatg acataaccag
    37861 ctaagaatcc accaatcagt gcacctaaga atcctgcacc gcctgtatta gctaatgcac
    37921 cagcagcaaa tccaacgatc aaaccagggc ggtcaccgat acttgaagca ataaatcctg
    37981 ctaataccgg cagcatgaaa ccaaatgcag cttgtccgat ttggttgaac cagctagcag
    38041 cttgattgta attccctaga tttgataatt gatcatgtgg cacgccaata aattggtcga
    38101 tcatgaaaga aagcgcaata gcgattcctc caccaataac gaaaggtaac atgtgtgata
    38161 cgccgttcat caaatctttg taaattcttt gtccgatagt accatccgca tttccttctt
    38221 ctgaactgct ttcttttcca tcaccatgga atactggtgc agtaccacta agggctagat
    38281 tgatcaactc ttctggttta cggataccat cactgacagg acgattgatc agttcttttc
    38341 cgtcaaagcg attcatctct acttttttgt ctgctgcaac gattacacct tctgcacggg
    38401 cgatgtcttc agcagtcaat cggtttttga ttccttctga accgttcgtt tcgactttga
    38461 tctccacacc catttctttc gcttttttct tcaaagcatc ttctgccatg taagtgtgag
    38521 cgatccctgt tggacaagct gtaacggcaa caacgaattt tctttctgga tgagcagaag
    38581 cttctgcagc ttgtgtttct tgttctgctt tttcttctgc ttctttttgc tcttcagctg
    38641 tttggaacaa gtcttggact tcttctggtg tatttgcttc ttttaatttt cctacgaaat
    38701 ctgcatcaat cagcaatcga gatagtgctg ctaatgcttg caaatgtgtg tcgtttgcgc
    38761 cttctggagc tgcgatcatg aaaaacagat aagttggctg tccgtctaag gcttcataat
    38821 ctactccttt ttggcttttt gcgaataaaa ctgttgcttc tttaactgca ctgtttttcg
    38881 cgtgaggcat ggcgattcca tcaccaagac ctgtagaagt ttgtgcttcg cgggctagaa
    38941 ttccttcttt atatgtttcg atatcggaaa tccggccggc atcaaacatt ttttggacca
    39001 tttcatcgat tgcgcctttt ttatcagtcg cttgcaaatc catgatcatc gcttctttga
    39061 ccattaaatc cttgatattc atgattatcc tccttgaaac taatcaattt ttgtgatttc
    39121 aacttctggc agcaactcat caatcaattc gcgagctgcc aagtcatcag aaaaagctgt
    39181 tgcgcttccg caagcaactc cccatttaaa ggcttcgatt ggatctttcg tacggctgta
    39241 agccccaata aagccagcaa tcattgaatc ccctgcacct actgaatttt tcaatgggcg
    39301 aactaataca ttcgttttat aagttccttg ttccgtgaag agcaaagcac cgtctccagc
    39361 cattgagatc agcacattct gtgccccttc agctagtaat tttttcccat acggaatgat
    39421 ttcttctaca gattggaagg ttgtgttgta aagctcagct aattcgtgat tgtttggttt
    39481 gatcaacaac ggtttcttaa caagtgcatt ttttaggtca tcacctgttg tatcaatcac
    39541 gaaatctgca cctttttctc gaatgatatc aatcagttct tgataaaatc cttttcgcag
    39601 gctagctggc gcgcttcctg acaatacgac gatatctcct tgtcctactg ttcctaatgc
    39661 ttgcttcaac tcatcgattt cttcatctga aatagatggg cctaagccat tgatctcagt
    39721 ttcagtgtct gattttagtt tgatattgat tcttgtatct tcttttacgg ttgtgaacaa
    39781 agactggatt tgttcttttt caagccactt cgaaataaat tcgccagtga accctcctaa
    39841 aaaccctagt gctgtagatt gagaatcgat ccgtttcaaa atacgggaaa cattgatccc
    39901 ttttcctcca ggtaacttga agtcttcctt cattcggttc aaatcgccta gttttaaccc
    39961 atctacgcgt acgatataat caattgatgg attaagtgtt actgtgtaaa tcattgtatt
    40021 gcctccttaa ttgttgtctt ttcacggaat tcattaacga attctaatgg acaacgctcg
    40081 gttatgatcg tggctgcttc caaaggtgca acagaggtga aggacaactg gttgaatttg
    40141 gtatgatcaa tcaatacaaa tgtctcttcg gaatttttca tggctaaacg tttaacagct
    40201 gcctcttctg gatccggagt cgtgaatcct tgttcaagat gggcaccgtt cattcccata
    40261 aatgctttat taaaatgaaa attttttagt tgttctatcg cattagatcc taaaacagca
    40321 ttagttgcca gctttatcgt tccacctaaa ataatggtag caagctccaa atcaactaaa
    40381 tttgccgcat gttgaacgga atttgtcact actgtgatct gttttccttg cagaaaagga
    40441 atcatttcta acgtagtaga gccagcgtct aaataaatga catcttcgtc attaatggtt
    40501 tcagctgccg atttggcgat ttgctgtttt tcgtgaacgt ttttgagtga tttttcactc
    40561 atattctgct caaaattcaa taattgctct ttcttagctc cgccatgaac tctttctaga
    40621 aacccactat tctccagctc ttgtaaatca cgtcttatcg ttgattcaga agcattcaaa
    40681 aggtttacaa gatcttgtga tttcacgatt ttctgctgtt caagcaagtc taggattttt
    40741 tgtctgcgtt cctctgtaag cattttcacg atcacctcaa tacaaataat agcatatttt
    40801 ttttctacta gcaatataaa tcagtcaaaa acgttcataa aaattataaa tcagtcaaaa
    40861 aaaaataaaa aaccagtcag aaagactggt tttttatttt tttgtctatc atcaagccgt
    40921 tttatcgttt tttattttcg cttcttgttt ttttcatata aacagaagca ggttttcttt
    40981 ccttatgaag aagataataa taaagtccca tcccgccaaa catgaccaaa aaaccgatga
    41041 ctgatcgaat aggaaaatta ggaacaaaaa agagacagac ggataataat gatgccggaa
    41101 ccattattcg ataatagagt tgtttatcca ttttcttcac ctcatatttt ttgtaaagta
    41161 atcaattgtt ctaattctcg gtaatctaaa aattgcacac gcagatgctg ctcacctttc
    41221 ttgacatcga attggatact tcgccgcttt ttctttattc gtttgaaggt aacatcagag
    41281 agtctatgtt tgatttcctt taacggtaat tctgacaggg attctgaagg aacatagatt
    41341 cttaaggata aaagatactc ttgatatttt tcatctgtta cctctacttc tagatattcc
    41401 ctaatataat aacaataagc ttcgattcca ttatccaaag caacagtcgg atcgataact
    41461 ttatagcaca tcatgcgtga tcgattctcg tcaacccaag gaaaatacgc ctgagcattt
    41521 agtgttccgc gaacacgcct ttctttataa tctccttgtt ggatatcata actttttgtt
    41581 acaaaaaatg aagcattctt tttaggaaca ggttgcattt gtgcattctg atactggaca
    41641 gattggatcg tatggtcagt gtaaatgtat tcaacgaatg gcggtttcaa taaaccgaca
    41701 ccattgtccc aagcaagatg atcaaaccca agctggtccc taaaatagga ttgaaacatt
    41761 tgattgtttg gcttttgcca gttaaagggg tctcgataaa gctggataca tatgacttcg
    41821 ttttctaatt ccttcacttt ttctacttgt tggatgtcga gaaaaatcgg tttagggatg
    41881 atttgatgat aatagcgact ataatacatt tcccaacacg aagtgaaaca taaaccttgg
    41941 taaaaaagat cgtatcctgg aaattggttg caatcgacta ctacttcccc gttttgttgt
    42001 ttcattttag gtaaatgttc gatttcatcc tttttctcaa acaatagccg ttgagagatc
    42061 tgttttgtat tgtgatagat aaactcgcta taagctcgca tataggcgaa caccccatga
    42121 gcaatcattt ttttctgaat gaagtctcga atcaaaaatt gcttttcttt gaaaacagag
    42181 atagacaata cattttttat caataattga ttatcttcca agcgaaaact acattcgttc
    42241 tcgtcatttc ctacaactaa ccaactttcg tctcttaccg atgctagcat tattttttct
    42301 tgaagctttc gaagatcata cggatccgct tgttgtgtga aagagcggat aaatgttggc
    42361 tggatcaaca gacgtgtcaa aatagcccaa tcgcttattt cctgtttttt ttcttcttca
    42421 tttaagtctg tgagctggat agtcatcaat aatttatctt cgccaatcat tttctcacct
    42481 ctttcaaatc tttttataat ttaattataa ccaatgataa agaaaaacta aaactttatg
    42541 tcttagaaac caatttggac gattacatga tagactaagt aaaaagaaac aaagaggtgt
    42601 ttacaatggg gttgaaattt gaacgtacag ataatttaga taaacttttc gaatcatttg
    42661 ctgtcgatcc ggaaaaaaca gttgcaccaa aagaagagat cgatcgattt ctaaaaccac
    42721 agccacaaaa tgaaaagaaa aaagacaaga aacaaaagta agttaagctc aaaaaaagac
    42781 ttaccagcca aacttttatg aaagagtttg actggtaagt cttttttatt ctttttatga
    42841 ttcaattgct tgttcgattg ctgcccacgc ttcttctttt ccctgttttg taacggaaga
    42901 aaagagaata aacgtgtcat tgcgatcaaa atccaacgct tttttgattt cgctctcatg
    42961 cttgttccat ttaccacgag ggatcttatc tgccttagtg gcaacaacaa ttacagggat
    43021 atcataatac ttcaaaaatt gatacatctg gatatcttct tgagaaggct tatgacgcaa
    43081 atctactaaa gaaacgaccg cacgtagctg gtctctagtc gttaaatatg tctcgatcat
    43141 ctttccccat tttgctcgct cagttttgga tacttttgca tacccatatc ccggaacatc
    43201 gacaaaatgt aatgcgttct cgatcaaata aaaattcaat gtctgggtct ttcctggctt
    43261 accggaagta cgggctaaat tctttcgatc aatcaatgtg ttgataaaag aagatttccc
    43321 tacatttgat cgtcctgcca gagctatttc tggcaattgt gtatctggat attgttttgg
    43381 tgccactgca cttatgataa tttcagcttg atggactttc atggtctctc tccttaacaa
    43441 ggtgatgaat aaagcaagcg gctgtcgcaa aagccaaaat gacttttacg gcagcctctt
    43501 ttcatcaacc cgcttttttc tctgaatctt tatagattac tgttggctca ccagacaatt
    43561 cagctgcttc ttttgtgata atcacttttt cgatgttttc atttgaaggg atatcaaaca
    43621 tcacatccat catgatttct tcaatgatgg aacgaagtcc tcgagcaccg gtattgcgtt
    43681 cgattgcttt tttcgcaatg gctctcaacg cttcaggttc gaattcaagt tcggtattat
    43741 ctagagaaag aagtttttga tattgtttga ctagcgcatt tttcggctca gtcaagatcc
    43801 gtaccagatc atctgttgtc aatttctcta aagctgccat aacaggtaat cgtccgataa
    43861 actcagggat caatccgaat tttagtaaat cttcaggaat gatatgctgc atgacacttt
    43921 cgtcttcaga aagtttttgg ttttgtgtac caaatccaat cgtcttttcg cccatacgat
    43981 tcttcacaat cgtttcgatg ccatcaaatg caccacctac gatgaacaat atgttcgtcg
    44041 tatcaatctg aataaattct tgatgtggat gtttacgtcc gccctgaggt ggcacacttg
    44101 caacagttcc ttctagaatt ttcagcaagg cttgttggac accttcgccg gaaacgtcac
    44161 gagtaataga tacattttcg cttttacgcg caattttatc gatctcatca atatagatga
    44221 tccctttttc tgcaagttcc acattgtaat cagcagattg aagcaattta agcaaaatgt
    44281 tttctacatc ttcccccaca taaccagctt ctgtcaaact tgtcgcatct gcgattgcaa
    44341 aaggtacatt caatgttttt gctaatgttt gtgctaaaaa tgttttacca gaccctgtag
    44401 gtccgatcaa gcagatattg cttttttgca gttcaacatc atctgtgttt tcttgtgctt
    44461 gctgattgac acgtttatag tgattgtata cggcaacagc taacgagcgt tttgcgcgat
    44521 cttgtccaat cacgtagtta ttcaatactt caagaatttc tagtggttta gggacttcag
    44581 tgaattcgcg tacagcttct tcataaaatt cttcatcaat gatttcttta cataggtcga
    44641 tacattcatt acagatgtag acccctggac cagctacgat ctttttcact tcttcttggg
    44701 ttttcccgca aaaagaacag cgtacggtct cattgctact tggattgtca tacatggtct
    44761 tcacccctta acttgcaaaa agtatgcaag aaactatcaa agactttaca gtcttttact
    44821 atcataacat agtttagtaa aaagaaaaag tgtttaacaa aggatcaact gacctatacc
    44881 tttgcatttt ttactcttaa caaaaaataa ggaactgtga caaaatcgtg tcacagtccc
    44941 ttatttcgaa taaacaattt tctagaagta gcttcttcag aaatgattta ttacttgatt
    45001 tctattcttt cgcttctgtc gctgtacctg tgatcaattc gattgctttt ttcattgtca
    45061 catcatgttc cagcatatct tctgtcaaca cgcgtttgat ttgttcgatt ggcatgttgt
    45121 atgtttctga taattcttgg atttctgcat tgatttcttc ttctgttgct tgaagatttt
    45181 cagcagctgc aattgcttcg atcacaagat ttgttcttgt gcgcatttct gcttcacctt
    45241 cgaattgttt atgcaagtct tcttctgtag aaccagttaa ttgatagtac atttcaggag
    45301 agataccttg acgttgcatg ttgttcaaga attcgtccat tgaacgatgt acttcatcat
    45361 gaaccatcac gtgtggcaat tcaacgattt ctgcgttttc aacagccata cggatcgctg
    45421 cttcatcttt tgcatcgtcc gctgcttttt cttttgtttc tactaattct ttgcgatatt
    45481 tttctttcaa ttcgtctaat gttgatactt cgtcatcaac atcttttgcg aattcgtcat
    45541 ctaattcagg cacttctttt gcttttactt catggattgt cactttgaag actgcttctt
    45601 ttccagcaag atcttctgct tgataatctt ctgggaaagt tacatttaca tctagacttt
    45661 cacctgattt atgaccaact aattgatctt caaaacctgg aatgaatgag cctgaaccta
    45721 attcaagtga gtaattttcg ccttttccgc catcaaacgc ttcgccatct acaaagcctt
    45781 cgaagtcgat tactactgta tcgccatttt cagctgcagc atcttctttg ataactaatt
    45841 cagcttgtgc ttcttgttca cgtttgatac gtgcatccac gtcagcatct gttacttcac
    45901 ggtcttgttt ttcaacaact agatctttat attgtcctaa ttttacttct ggtttcactg
    45961 ttacttcagc agtgattacc cagtcttgac ctttttccat gctttcaaca tcgatttttg
    46021 gttgagaaac aggatcgatg ccagcttctt tgacagcagc ttcataagct tctggtaata
    46081 cagcattcaa tgcatcttca tataaagctt cttcaccgta catacggttg aatacttgac
    46141 gagaaacttt ccctttacgg aatccaggta cgttcaagct ttttttcact ttattaaacg
    46201 cagttgttaa tcctttttgg atttcgtctt gcgcaatcgt aaattttaaa acaccatcat
    46261 tcgtgccttt tttttcaaat gttgcagtca tttaattccc tccgagttta gaaattcatt
    46321 ttatacatca aaaacgtttc atgcatacct ttaaatagta cactaaccct ttcaaattgt
    46381 aaacatattg aatggataga atccttgttt ttcataacat ttttatcttt ttcactgata
    46441 aaatctaatg gaagaagatc atttgctgca aaattttttc tctttttttt aaaaaatctt
    46501 gtttttcatc ttctgtacct tcatacatcg tttttcctgt acacgcctct acagtcagtt
    46561 gaaaccagcg cttcgggtct tcgatgtatg tatcatagac aggataaaca attgcagatt
    46621 gcaacgtgaa ttcttctttt aacacggaac taagcagcgc atcttcattc ccgtaacgat
    46681 ctgaaaatac acataattgc tggtaacttg cctgctgctg cggctttggc agatcttttg
    46741 gtatgacttt gactaacttt tcttcaatcg tcaaatagaa aacttgatgg cattcgttca
    46801 attgcctaag tgtctccagt aattttgccc ttgctaaaat atggacctct ggcgatacaa
    46861 taagtttact cgctgtttgg ataaactcat gataaggaag ctgttcgatc tcatcaatag
    46921 acgcaagctg acgtgcaggt tccaacgaag gaagttcctc cgatttattg tggagtgcct
    46981 tgatcttctg cctctccatt tgtccggata attcttctgc aaattggatt ttttcaatga
    47041 cccgctgctc gaaagcttca taaaaatctg tacttgctat caattttcta gcatataaaa
    47101 aatcttgtgt actgattaac aagtcaaaat aaaattcagc aaactcctca ttttgaagat
    47161 actgtttttc atgcaagagt gcttgcttca atgcttcttt tttctcgtcc aactcgtaaa
    47221 gacaaaaaac aagcaggcta ttagcctcaa agctttcttt caactcgtaa gctcgttgaa
    47281 ataattcttt tgcctgctga tattgctggt ttgctagtgc ttgttgtgcc actcgcatta
    47341 aattctcata tttttctgga aaatcaatcg gcttcacgca gtgtcctcct cttgctcata
    47401 ttcagctcat gttcaatagt agcaaaacaa aaaaagcatg acaattaaaa ataactgaag
    47461 caccctctaa aagctagatt ttagatctga cttttagaag gtgctttcaa ctgttactgc
    47521 tttttattgc tcatcagctg ttgacttcct ggttgaacgc tttgatcaga ttgatcgtaa
    47581 caacacttgt attagtgaaa aaatcgccca gatgttgctt tttctgatta aagactgctg
    47641 gaagataccc taacatcagc aaaggaaatt ttagaatgaa ccggcaagca ccttctctaa
    47701 ctaaaacggt tgaccagcta agttcttctt catcaaagct gatgactcga ataccaaaga
    47761 tcattttccc aatcgtttgg ccatgattga atttcgtcaa taaaataaaa tacgctagat
    47821 aaataagtaa ggctgtgaat ccgtagagac tcagataaga atctgaaaaa ttaagccaac
    47881 ctagattttt ggcaatacca agtgttaaac gcgtaatagc tccgatacac aaaagatcga
    47941 ccaagaaggc aaacattcgg ataaaaaaac ctgcatagaa atacttagga aaatcatttg
    48001 cttttggcgg ttcatttctt gtgtccgtat actttttcca tttacgttgt ttctttttga
    48061 tttcttcggg cgtcaaaggc tctctttcaa aagagctcag taccttttgg gaaaagttgg
    48121 agtcaggtcc tacagcaggc tgctgttgct tatctttttc ttgttcctta ttttcatttg
    48181 aaagctctga catgcttact cacctccgta ataatacatt gcttttggtg attccgctgt
    48241 ccctagattc tcaagaacgg ataagatctg actagtctca gaaggcttca atccctggaa
    48301 ttctgctagt ttacttccta accatgtact agcaaaccca gatggcgtgg aagaatattc
    48361 tactagttcc gcatcttcaa gctgttgttc ctttcgtata gcttttaaag catcttcagg
    48421 aaatcccaat tcatcgacta aacctacttc ttttgcttgg acaccatcat aaatccttcc
    48481 atcagcaatt tttttgactt cttcttcaga tttattccgt ccctcgctga cgattgctac
    48541 aaaacgacta tatgcgctgt cgatatatgc ttgaagcacc gcttcttctt cttttgtctc
    48601 tggtcgcgtt cctgaaccca tatctttcaa cgctccgctt ttaactgttg tatcttccac
    48661 acccagtttt tctagaagtc ctgaataatt caatcctgac atgatcacac caattgagcc
    48721 ggtcactgtt tcttctgttg caaagatttt atctgcttga gcagaaatat agtagccacc
    48781 gctagctgcc atgtttttca tgctgacata cattgggata tcatgttctt tacgaatcgt
    48841 atccaatttc ttagcgattt ccgcactttc gtagacaccg ccaccaggag aatttacttc
    48901 taaaaagata cctttgactg ttggatcttc ttcaatcgcc ttcagttgtt ccataaaatt
    48961 tttatgattg taaccttcag aagcaaataa acctgaagac cctcccgcag caatcgttcc
    49021 atctactgat aattttacga ttttttgcgt actgtctccc tcttccaaca catttggagc
    49081 tagttcttca tccccatata accaactgtt caatccctca atttgatcgt tttcctgagg
    49141 cttagtcaaa ctagctgaaa ctaacgaaac cacaaataat cctgcagcaa tcagaactgc
    49201 tgcccaacgt cttttattca ttctttctcc tttctaatac aagtttttta tgacgatcac
    49261 agtttctgac tgctcagaag tgtcgaaccg ctctgctttt tcttcccgcg catacccgga
    49321 aaacgactct tttgttaatt catcttctac cgtaaactca cgagcttgag caacttccaa
    49381 ggcatcaggt gcgatttctt ggatgctatc ccagccagta tctaaaaata ttttcgtatc
    49441 atctgataca ccagctgatg cttcgaattt ggacaattgt ttttttaaca ttcccagtgt
    49501 catgatctca atttttgaat ccatttttac tcctcctcta tccgattact ttctattgta
    49561 ccgaactcct gaaaaagatg atagataaaa acccattatt ttttgacata aaaaggacat
    49621 ttgacaaaga atttgatata taccaattta ttttttattc tttttttgtt gacaagaaca
    49681 ttcgcaaaag gttatgattt taaatgtttc cagataaaaa acaaaaagga ggatagttat
    49741 accttttagg atagcgccag gtctgtgtaa acagatgacg aggagagggt ttatcgaaag
    49801 attcggcgga tggccctagg gactgcactc tacagaaaat ccacaaaaaa tgtctgcaaa
    49861 gataaaacaa aaggattttc ctgcagctgg aagcattcat acgaattcat tatagaaagt
    49921 aggatgtttt ttatgtgcgg aattgttgga atgattggat taaaaaatgt aacaccagga
    49981 ttgattgacg gtctagaaaa attagaatac cgtggttatg attcagctgg tatctttgtc
    50041 tcagatggca caactgatta tctggtcaaa gcacaaggca gaattcaaaa tttgaaaaac
    50101 aaaataaata ttgatactac aggaaatata ggtattggtc atacacgatg ggcaactcac
    50161 gggcaacctt ctgaagaaaa cgcccatcca catacttccc aaagtggacg cttcgtgctc
    50221 gttcacaacg gcgtaatcga aaactttgaa gaacttaaaa ttgcttattt agcaaatgac
    50281 cactttattg gtgagaccga tactgagatt atcgctcatc taattgaaac tttcgcgaag
    50341 gatactacaa cgcaagaggc gtttttaaaa gctttgcggg tcatcaaagg ttcttacgct
    50401 ttcgctttga ttgatcggac agcacctgat gttatttacg tcgctaaaaa taaaagtcca
    50461 ctattaatcg gactcggcga tggattcaat gtgattgcca gcgatgcaat ggctatgctt
    50521 gctcatacga aggaattcgt tgagattgaa gatgaagaga tggttaccgt cacatcagaa
    50581 aaagttatta ttcaaaattt tgcaggtgac atcgtagaac gttcttcatt cgaagcacaa
    50641 gtagatgctt cagatatcga gaaaggtacc tatccttttt atatgctgaa agaaatcgac
    50701 gaacagccta ttatcatgcg tcgtatcgct caaaaatacg taacagaaga caatcgtgtc
    50761 tctcttgatc aaaagctggt cgatacattg tctgatagcg atcgaatcta tatcgttgct
    50821 tgcggaacta gttaccatgc ggggttagca ggtaaacaga ctttggaaaa attgacacag
    50881 attcctgttg aggttcattt agccagtgaa tttggctata acacacctct tctttcaaaa
    50941 aaaccattct ttattttctt gagtcaaagt ggcgaaacag cagacagccg ccaagtgctg
    51001 gtaaaaatca accgtctcgg ctacccttca cttacgatta caaatgttgc tggttctact
    51061 ctttcgcggg aagcatcctt tacactgcta ttgcatgctg gacccgaaat cgcagtagca
    51121 tcaacgaaag cttatactgc acaaatagct gtactaactt tattagccaa agctatcggt
    51181 gataaaaaag aatttgaaac ttctcttgta ttcgatatca ctcatgaatt gagtttagtt
    51241 gctaatgcga tggaatcggt catcgcccaa aaagattatt tagaagagtt ggcagaagta
    51301 tatctcagcg atacaagaaa tgccttttac attggacgtg gtgctgacta caacgtttct
    51361 cttgaagctg ctttgaaatt gaaagaaatc agttatatcc aggcagaagg ttttgccgct
    51421 ggcgaattga aacatggaac gattgctttg atcgaagaag gaacaccagt gatcggaatc
    51481 atcagtgaag aagtgactgg tgcgcatact cgaggaaacc tgaaagaagt cgaaagccgt
    51541 ggcgctaaaa cactagttat tgtctcagag ggattagaaa aggaaagtga ccagctggtg
    51601 ctaccaactg tccaccctta tctaactact ctaaccacag tcgtaccgac tcaattactt
    51661 gcatattacg caacgctatt acggggattc gacgttgaca aaccacgtaa tttagcgaaa
    51721 tcagtgacag tagaataata aaagaacaag gaccagtgtc agacatctga cactggtcct
    51781 tgttctttta ttttttatga aaatatctct taatccagtc cgatttcttc tttgactact
    51841 gccgcgattt tatcgacata gtaattaact ttctcatcag taggcgcttc tgccatcact
    51901 cgaagtaatg gttctgtacc ggaaggacga actaggattc ttccttctga tcccatttca
    51961 gcttctgcct cttcaatcac ttttttgatt gccggaacat ccatcgcacc gtttttatca
    52021 cttacgcgga tattcactaa tttttgcgga tagattgtta cctctgctgc aagctctgat
    52081 aatttcttac ctgtctgttt catgatattc agtaactgaa ttcctgaaag catcccatct
    52141 ccagttgtgt taaaatctaa gaaaatcatg tgcccagact gctcgccgcc aaagttataa
    52201 tcgtttttgc gcatttcttc tacaacgtaa cgatcaccaa cttgtgtaac gacatctttc
    52261 aaaccgattc cttccaccgc tttgtggaat cctaagttac tcatgacagt cgtaacgatc
    52321 gtatcttttt tcaatcgatt tttttctgcc aagtatttag cacagataaa catgatttta
    52381 tcaccgtcga caatgtttcc aagttcatcc accgcaataa tacgatcgcc atcgccatcg
    52441 aaagctagtc cagcatctgc tcctttttca acgaccatct cagctaaacg ttctggatgg
    52501 gtagagccta cgccgtcatt gatatttaac ccgtctggat ttgtgcccat tgtataaaaa
    52561 tctgtttcaa gatcggcaaa caaacgatta acacttgttg aagttgctcc gtttgctgca
    52621 tcgacacaaa tggtcaaacc ggaaaggtca ccgttgatcg tttgtacaag gaattgagaa
    52681 tatttcaata agccttctgg aaattcttct acagttccca atccttcagc tgatggacga
    52741 ggcaattcat ccacttcagc atctaataat gcttcaattt ctagctcttg gtcatctact
    52801 agtttaaaac catctgcacc gaaaaatttg attccattat cttgtgctgg attatgagaa
    52861 gcagaaatca tgacccctgc gcttgctttt tgcaaacgtg tcagataagc aacacctggt
    52921 gtagagatca cacctagctg gaacacttcg atacccaccg ataaaagtcc tgaaatcagc
    52981 gcttcttcta acatttgacc tgagattctt gtatcccgcc ctactaacac gcgtgggcgt
    53041 tttccttctt cttcatgctg gcttaggaca taacctccgc accgtcccag cttaaatgca
    53101 agttctggcg taagttcctt gttggcttca ccgcgtacgc cgtctgttcc aaaatattta
    53161 cccatagttg taaaattact cctttaactt aattttctga ggaatttgtt ctgctcattt
    53221 gtgttgattc gcttgtttct gatgtttctt ctgtacttgt ggtcgagctg cttgtcccag
    53281 attccgaact ggaagaaatg gttgttgtcg atggttccgt tcctgaatca gcagatgaaa
    53341 tacttctact cgtacttgta ttttcttgtg tccgactgct cgtcgaagca gagctactgc
    53401 ttgacgtttg caacacgggt gtaatctcca cactaactga ttcgggcttg atacttaacc
    53461 cctcttctac tggtatttca attttacgag ttgttcgatg attgatacct gagacattga
    53521 tcggtacagc aatactgtca ccgatcgatg caagcaaatc gctagagccg cttacttctg
    53581 cttccagttt tgaaaaactg aaatcatagc tttctacccc ggcagctggt gttccttgct
    53641 gtatcccata aagtcgtacc gacttgcttg gcttgatcga atcagctctc actgttactt
    53701 gcactggatc agagacgata cttaatactt cccctgctgc attcagcgcc tgtattggga
    53761 cctcactatt aatcccatca tctgtgacca tcgaagcgtc cacatcagct actactcgtt
    53821 tgatttctgc caatgttttg tcacctgtag tgatagagac ttttttagga ctaacggaag
    53881 tatcatcaag ttcatatcca gatggtgtga acgttgaagg aatcaacgtt tccacatcga
    53941 aatcttttat tacctttttc tcaaccgtta ctgtaatagt cgatggttcg atctttgctg
    54001 tgacagcact gctcaaattt tgaattttta gcggaacttc atgtgttcct tcgcccagct
    54061 tagtgatatc tgctgtgacg cggaacatcc gtgtatcttc gtttgcctct gcattcaact
    54121 gaactcggtt tgcactggaa agtttgacag tcactgcatt ttcatatcca tggatatagt
    54181 agcgctttga atcataagaa atcttgatcg gcacccccgt aactgtttga ttatacgctt
    54241 catttccaga aagcgtattt ggaacggact ggccatttgc attgaagtac agcgcaatac
    54301 tgaacagcaa tgcaataaaa ctgtaaagaa tgcttgtccg tttctctttt gagatcattt
    54361 gcgatcccct cccttagtca taccgtctag gaaagattga atcacgtttt tcttgttttt
    54421 tgttttctct tcagcaatta gttctctacg caagattgcc aaatattctt gctgggataa
    54481 gccagccatc agttcattat ctaacgtgat gctgacgtcc ccggtttctt cagagacaac
    54541 gatggtaatc gcgtcactga cttcgcttat accgacagct gcccggtgtc gagtcccgaa
    54601 ttctttaggg atcaacatac tttctgatag aggaagatag gcgcttgcta ctgcgatctt
    54661 tccttctttt acaataactg caccgtcatg cagcggtgta ttaggaataa agatattgat
    54721 cagcagctcc ccagtgatat ctgcatctaa agcaatccct gtctcaatat actcatctaa
    54781 tccagtatga cgttcgatag tgatcaacgc accgattttt cgcttggaca tatattggat
    54841 ggctttgtca aaagacaaga tcatcttctc atcttcctgc tgttcgcttt ttgattgttt
    54901 gaaaagcgaa ctgcgtccaa gatgttccag tcctctccgg atttccggct gaaaaatcac
    54961 gatagcagct atcaccccgt acgtaatgac ttggttcatc agccaagaca aggtgtgcag
    55021 accaatgatt tccgctacga ttcggataac aataaaaata gctacacctt tcagaagctg
    55081 aatcgctttt gtgcctcgca gcagttggat cagtttgtat acaagatacc agacaaccag
    55141 aatatcaagt atgttcacca aaaaattcag agagaacaag tcaccggaaa acatttgctg
    55201 ccaatagtcc aaattaaaaa gttccccgat ttgaaatgac ataaaaagcc tctcttctct
    55261 tttgagattt cctctctagt atatcatatg ttttaatttt agaggctgat atgctcgtat
    55321 ttttcttgag aaaaacgcat aattttcaag aaaattgcaa gtatgcgttt tatttttctc
    55381 tgcaataaat atttttaaac ttcagagaat tattcattat attttttctg ttatttttcc
    55441 tttttttctt ttgtagcttg ttccattttt ttacgtcgtt ctgctctggc agctcttcta
    55501 gcagctcttc tttcttctgc ttcaaggtcc gtcgtttttt cttttctagt cttaacgggt
    55561 acatcgatag attcctctgg ttcaagtcgt ttcttgattt tttctaattc tcccgtcagt
    55621 gcagcatagt tgtaaaaacg tgttttagcg tcgtggacag tcttttcaaa taaagctttt
    55681 gcaagatttg gatttgcgtt atctagcgag gaaaagcgaa cttgtttcct catgaaatca
    55741 ggcatagcag agaaatcagg ttttttgtag tccaaagtca ttgggttctt gtttttttcg
    55801 accattgtag ggttatatcg atataatgac caataaccag aagaaacagc ttcttttgct
    55861 tctttaagcg attctttcat tccgccaagc aagccatgtg tgatacaagg cgtataggca
    55921 ataatcagag aaggaccagg atacttttct gcttcttcaa atgccttgat cgtttgcatt
    55981 tgattggcac ctgaagcaat ttgcgccaca taaacatttc catatgtcat cgccatcatt
    56041 cctagatctt tctttgaagc atactttcca ctagccgaaa atttagcgat tgccgaagct
    56101 ggtgttgctt ttgaggtttg accgccagta ttggaataga cttcgttatc caaaacaagg
    56161 atattcacgt ctgctccgct ggcaagtaca tgatcgatcc cgccaaaacc aatgtcgtaa
    56221 gcccatccgt ctccaccaat catccattgg ctgtttttta cgaatagatc ctttctcttg
    56281 tatatatcct ccagttcagg gaaaattgat cgttcgcttt cgatcgcagc ttgcagtttt
    56341 gctgctcttt gctgcgttcc ttcactctca aacatgtgta ctaaccagtc ttccatcaat
    56401 tctcgtagtt cttctgatac ttttggcaat acttctttga ttgaacttgc caaagcctcg
    56461 cgacgagtct gtgccgctag aagcatacca taaccaaatt cagcattatc ttccaataaa
    56521 gaatttgacc atgcaggccc ttgaccacat tcattggtcg tataaggaga agcaggagaa
    56581 gcaccgcccc aaatagaaga acagcctgtc gcattcgcga tcatcattcg atcaccgaac
    56641 atttgtgtca ataattttac ataaggtgtt tcgccacagc ctgagcaagc gcccgagaat
    56701 tcaagaagcg gttgattgaa ttgtgtagac aagacagtat tctttccttt gactggattt
    56761 gctttttgtc ttaatgtcat tgcaaaagcc caattcacag cttgttcttt ctgttcttca
    56821 taaggcttca tcactaaagc tttttctttt gcgggacaag cctctacaca cagaccacaa
    56881 cctgtacagt cttccactga aacttggata cggtatttta cgccgtctgc gcctcgcatt
    56941 tctctcacga taaatccttc tggcgcttct tccatttcct cttcatctgc taaaaatgga
    57001 cggatggcag catgaggaca aacaaaggca cattcattac acatcgtaca gcgatcacta
    57061 atccactcag gtacttctaa agcgacgccc cgcttttcca tagaagccgt tcctaaaggc
    57121 atttcgccag ttgtcattcc atttgctaca agtgtaccaa cagagagttg atttccttcc
    57181 tgtgcattca ctggttcaag tatttcttgt atataaccag tgttcctttt attgattttt
    57241 tcaggcatct ccaacgttct ccaatggtct gggatcgcga cttgatgaag cagttcggtc
    57301 gtccgatcga ttgcttgtat gtttttttct acgatagcca ttgatttatg tccatagctt
    57361 ttcagggctt cttcttttag cagcggaagc acctcatcaa aaggaatgat gtcagctaat
    57421 ttaaaaaaag ccgtttccat tgccgtattg atccggcgtc ccaaaccgac ttcttgggcc
    57481 aatctcatgg cattgatcgt atagaatcta atgttatttt cagccaagta acgttttaat
    57541 tttaagggca gatgcgtttc taattgttcg tcgctccaaa gagtattcaa taaaaaaatg
    57601 ccacctggct tcaatccttt gaccaagtca tagctatgca ggtaagctgg tgtgtgacag
    57661 gcaacaaggt ccgcatgctc gacaagatac gctgaacgta tcggcgtatc tccaaaacga
    57721 agatgagaga cagtcagacc gccagatttt ttcgaatcat aataaaaata gccttgcgca
    57781 tatttatcgg tgtgatctcc aataatcttg atagctgatt tatttgctcc aactgttccg
    57841 tcagatccaa atccccaaaa cttggcctgg aatgtttgcg gttctgtcaa atccagactt
    57901 tcctttggtt ccaaagattg ataagtcaca tcatccacga tccctatggt aaaccgtttt
    57961 ttgcgtatgc ttgggtcttt tttcaattca tcaaaaactg ctgagatttg gtcgggagtc
    58021 acatctttag accccaatcc gtagcgacca ccaataacag ccgggcgaag ttcagaatca
    58081 tataacgcac tttgaacgtc taataagaga ggttctccac ctgcccctgg ttctttactt
    58141 cgatcaagaa cagcaattgt ttttactgta tgaggcaact tttgcacgaa tgtttccact
    58201 ggaaaaggac gataaagatg gatattcaaa aaacctgttt tccgtccgtt tgcattcaag
    58261 taatcaatcg tttgttcaat cgtctgtgca actgatccca tagaaacaat gacttcttcc
    58321 gcatcgtctg ctccgtaata agtcaccaag tcataagaag ttcctcgtaa tcggttgatc
    58381 tctttcatat atttttgaac gatttcaggt aatttatcat aataggggtt gatcgtttcc
    58441 cgttgttgaa aatggatgtc tggattctgg ttcgtaccac taacagtcgg atgattggga
    58501 ttcatccctc gtttacgaaa tgaagctaat ttctcctgat tgatcagagg agctaattct
    58561 tcatattcca aaacttcgat tttttgaatc tcgtgactcg tacggaatcc atcaaagaaa
    58621 ttcaaaaaag ggacttctcc ttcaatagaa gcaagatggg caacaggtgc taaatccatc
    58681 acttcttgta cactgctttc agctaacata gcaaatcctg tttgtcttgc agccatcacg
    58741 tctccgtgat ctccgaaaat attcaacgca tttgtcgtca ctgcccgact agcaacgtgg
    58801 aaaacacttg gcagtagttc cccagcaatc ttgtacatat tcggtatcat caaaagcagc
    58861 ccttgtgaag cggtatatgt agttgtcagt gcaccagttt tcaatgatcc atggaccaca
    58921 ccagctgctc ctgcttcgga ttgcatttct actactttta ctggttgacc gaatacgttt
    58981 tcttttcctg ctgctgacca ttgatctact aattcagcca tggtcgaact gggtgttatt
    59041 ggatatattg cagcaatctc ggtaaatgca taagaaatat atgcggctgc cgtattgcca
    59101 tccattgttt tcatttttcg catgattcat catccttgtt catattctct cttattatct
    59161 gttccattat aacgtaaaac atgccatttt tttcttttat ttataaaaat attttacatg
    59221 tatctatttg aattggtcat ctaattttta gacaaacagt ctaaatcgtt gccttttttt
    59281 gtcagacatg tataaactat aagcgaaaga ggtgttttaa catggatata tcagtgattg
    59341 atgcaacgaa aacaaataca caaaaaggaa tcctttatgg ttcatcgaat gctcctaaaa
    59401 aaatggtcga attcatcaac ttagcttgtc cgtattgccg acaatggttt gaagaatctt
    59461 atgagctatt agaagaagca gtccaaagcg ggcaattgca gcgagtgatc aaattgttcg
    59521 ataaagaaaa agaaagctta cagcgaggga acgtgatgca ccggtatctc acaatcagcg
    59581 atggccaaaa agcgatcaaa gagatcaaac aaatattcga tactcaagac gagtggaaac
    59641 atctttctct ccaagaagta gcggattttg cagtagataa actaaagctg acagaacaaa
    59701 aagacgaaca gctgagccaa gctgtcatca acgaagctga gcaagcacat attcgatttg
    59761 ttccaactgt catcttgggt aaagaaatct ttgatgaatc tatttcaata gaggaattaa
    59821 aagaattgat ccaaacaaaa taaaaaaata aggagcgtg
//
LOCUS       DBBGRF010000013        55502 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000013 DBBGRF010000000
VERSION     DBBGRF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.013"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            558..3197
                     /locus_tag="ACIZD4_000881"
     CDS             558..3197
                     /locus_tag="ACIZD4_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC5989834.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3365..4063)
                     /locus_tag="ACIZD4_000882"
     CDS             complement(3365..4063)
                     /locus_tag="ACIZD4_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGC5989835.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4281..5426
                     /gene="tgt"
                     /locus_tag="ACIZD4_000883"
     CDS             4281..5426
                     /gene="tgt"
                     /locus_tag="ACIZD4_000883"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGC5989836.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5523..5903
                     /gene="yajC"
                     /locus_tag="ACIZD4_000884"
     CDS             5523..5903
                     /gene="yajC"
                     /locus_tag="ACIZD4_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGC5989837.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6208..8805
                     /gene="adhE"
                     /locus_tag="ACIZD4_000885"
                     /gene_synonym="adhC"
     CDS             6208..8805
                     /gene="adhE"
                     /locus_tag="ACIZD4_000885"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGC5989838.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9034..10140
                     /locus_tag="ACIZD4_000886"
     CDS             9034..10140
                     /locus_tag="ACIZD4_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC5989839.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10157..11185
                     /locus_tag="ACIZD4_000887"
     CDS             10157..11185
                     /locus_tag="ACIZD4_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HGC5989840.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11191..11670
                     /locus_tag="ACIZD4_000888"
     CDS             11191..11670
                     /locus_tag="ACIZD4_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HGC5989841.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11686..12981
                     /locus_tag="ACIZD4_000889"
     CDS             11686..12981
                     /locus_tag="ACIZD4_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HGC5989842.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12992..13816
                     /locus_tag="ACIZD4_000890"
     CDS             12992..13816
                     /locus_tag="ACIZD4_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGC5989843.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13981..14880
                     /locus_tag="ACIZD4_000891"
     CDS             13981..14880
                     /locus_tag="ACIZD4_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989844.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15006..15875)
                     /locus_tag="ACIZD4_000892"
     CDS             complement(15006..15875)
                     /locus_tag="ACIZD4_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGC5989845.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16028..17488
                     /gene="rhaB"
                     /locus_tag="ACIZD4_000893"
     CDS             16028..17488
                     /gene="rhaB"
                     /locus_tag="ACIZD4_000893"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HGC5989846.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17485..18741
                     /gene="rhaA"
                     /locus_tag="ACIZD4_000894"
     CDS             17485..18741
                     /gene="rhaA"
                     /locus_tag="ACIZD4_000894"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HGC5989847.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18755..19600
                     /gene="rhaD"
                     /locus_tag="ACIZD4_000895"
     CDS             18755..19600
                     /gene="rhaD"
                     /locus_tag="ACIZD4_000895"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HGC5989848.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19602..19913
                     /gene="rhaM"
                     /locus_tag="ACIZD4_000896"
     CDS             19602..19913
                     /gene="rhaM"
                     /locus_tag="ACIZD4_000896"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HGC5989849.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19995..21146
                     /gene="fucO"
                     /locus_tag="ACIZD4_000897"
     CDS             19995..21146
                     /gene="fucO"
                     /locus_tag="ACIZD4_000897"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HGC5989850.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21273..22031
                     /locus_tag="ACIZD4_000898"
     CDS             21273..22031
                     /locus_tag="ACIZD4_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HGC5989851.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22131..22775
                     /locus_tag="ACIZD4_000899"
     CDS             22131..22775
                     /locus_tag="ACIZD4_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGC5989852.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22782..23789
                     /locus_tag="ACIZD4_000900"
     CDS             22782..23789
                     /locus_tag="ACIZD4_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HGC5989853.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23805..24647
                     /gene="kduI"
                     /locus_tag="ACIZD4_000901"
     CDS             23805..24647
                     /gene="kduI"
                     /locus_tag="ACIZD4_000901"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HGC5989854.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24667..25470
                     /locus_tag="ACIZD4_000902"
     CDS             24667..25470
                     /locus_tag="ACIZD4_000902"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGC5989855.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25719..26783)
                     /gene="fni"
                     /locus_tag="ACIZD4_000903"
     CDS             complement(25719..26783)
                     /gene="fni"
                     /locus_tag="ACIZD4_000903"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGC5989856.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26780..27865)
                     /locus_tag="ACIZD4_000904"
     CDS             complement(26780..27865)
                     /locus_tag="ACIZD4_000904"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGC5989857.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="ACIZD4_000905"
     CDS             complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="ACIZD4_000905"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGC5989858.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="ACIZD4_000906"
     CDS             complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="ACIZD4_000906"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGC5989859.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30108..30767
                     /locus_tag="ACIZD4_000907"
     CDS             30108..30767
                     /locus_tag="ACIZD4_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HGC5989860.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            30852..31757
                     /locus_tag="ACIZD4_000908"
     CDS             30852..31757
                     /locus_tag="ACIZD4_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGC5989861.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31759..32391)
                     /locus_tag="ACIZD4_000909"
     CDS             complement(31759..32391)
                     /locus_tag="ACIZD4_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HGC5989862.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    32542..32667
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            32711..33235
                     /gene="infC"
                     /locus_tag="ACIZD4_000910"
     CDS             32711..33235
                     /gene="infC"
                     /locus_tag="ACIZD4_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGC5989863.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33307..33507
                     /gene="rpmI"
                     /locus_tag="ACIZD4_000911"
     CDS             33307..33507
                     /gene="rpmI"
                     /locus_tag="ACIZD4_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGC5989864.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33560..33919
                     /gene="rplT"
                     /locus_tag="ACIZD4_000912"
     CDS             33560..33919
                     /gene="rplT"
                     /locus_tag="ACIZD4_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGC5989865.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34171..35508
                     /locus_tag="ACIZD4_000913"
     CDS             34171..35508
                     /locus_tag="ACIZD4_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HGC5989866.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35556..37685
                     /locus_tag="ACIZD4_000914"
     CDS             35556..37685
                     /locus_tag="ACIZD4_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HGC5989867.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37660..38349
                     /locus_tag="ACIZD4_000915"
     CDS             37660..38349
                     /locus_tag="ACIZD4_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989868.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38757..39370)
                     /locus_tag="ACIZD4_000916"
                     /pseudo
     CDS             complement(38757..39370)
                     /locus_tag="ACIZD4_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39506..39700)
                     /locus_tag="ACIZD4_000917"
     CDS             complement(39506..39700)
                     /locus_tag="ACIZD4_000917"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989869.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39750..40190)
                     /locus_tag="ACIZD4_000918"
     CDS             complement(39750..40190)
                     /locus_tag="ACIZD4_000918"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HGC5989870.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40194..41039)
                     /locus_tag="ACIZD4_000919"
     CDS             complement(40194..41039)
                     /locus_tag="ACIZD4_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGC5989871.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41188..42606
                     /gene="pepV"
                     /locus_tag="ACIZD4_000920"
     CDS             41188..42606
                     /gene="pepV"
                     /locus_tag="ACIZD4_000920"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGC5989872.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42663..43610)
                     /locus_tag="ACIZD4_000921"
     CDS             complement(42663..43610)
                     /locus_tag="ACIZD4_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC5989873.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43833..44183)
                     /locus_tag="ACIZD4_000922"
     CDS             complement(43833..44183)
                     /locus_tag="ACIZD4_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HGC5989874.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44383..45462
                     /gene="pepA"
                     /locus_tag="ACIZD4_000923"
     CDS             44383..45462
                     /gene="pepA"
                     /locus_tag="ACIZD4_000923"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGC5989875.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45606..45926
                     /locus_tag="ACIZD4_000924"
     CDS             45606..45926
                     /locus_tag="ACIZD4_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGC5989876.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45948..46412
                     /locus_tag="ACIZD4_000925"
     CDS             45948..46412
                     /locus_tag="ACIZD4_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC5989877.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46617..47222
                     /gene="ytpR"
                     /locus_tag="ACIZD4_000926"
     CDS             46617..47222
                     /gene="ytpR"
                     /locus_tag="ACIZD4_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGC5989878.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47261..48550)
                     /locus_tag="ACIZD4_000927"
     CDS             complement(47261..48550)
                     /locus_tag="ACIZD4_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HGC5989879.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            48978..49457
                     /gene="rlmH"
                     /locus_tag="ACIZD4_000928"
     CDS             48978..49457
                     /gene="rlmH"
                     /locus_tag="ACIZD4_000928"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGC5989880.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            49542..50051
                     /locus_tag="ACIZD4_000929"
     CDS             49542..50051
                     /locus_tag="ACIZD4_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HGC5989881.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            50151..50801
                     /locus_tag="ACIZD4_000930"
     CDS             50151..50801
                     /locus_tag="ACIZD4_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989882.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            51252..52190
                     /locus_tag="ACIZD4_000931"
     CDS             51252..52190
                     /locus_tag="ACIZD4_000931"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HGC5989883.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            52203..53255
                     /locus_tag="ACIZD4_000932"
     CDS             52203..53255
                     /locus_tag="ACIZD4_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC5989884.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            53521..54156
                     /locus_tag="ACIZD4_000933"
     CDS             53521..54156
                     /locus_tag="ACIZD4_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HGC5989885.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            54347..55138
                     /gene="msrA"
                     /locus_tag="ACIZD4_000934"
     CDS             54347..55138
                     /gene="msrA"
                     /locus_tag="ACIZD4_000934"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGC5989886.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT        17619 a         9922 c        11894 g        16067 t
ORIGIN      
        1 aaaaagccga gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca
       61 gaaatgattg taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa
      121 acaaaaattt tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat
      181 tttcagacgt ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt
      241 cgtgatccaa acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct
      301 gggtgaaacc tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt
      361 ctgtctattt gatggtatcc tccttcctta catctatata atagcatcct ttggtagcgt
      421 ttgcaaatat aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta
      481 tttgaagtaa ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat
      541 tttaaaggag gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa
      601 cagaagcaga tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc
      661 agggattgaa taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa
      721 gcttgtccga ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg
      781 catttgctac agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga
      841 tcaactcggt attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc
      901 aagatatgaa taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt
      961 cagagcaact ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg
     1021 atgcccgttt gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa
     1081 gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc
     1141 aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca
     1201 ctgccattgg catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta
     1261 tgcaaaaaac acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg
     1321 ctttagcggc tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg
     1381 agatgttcat gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta
     1441 ttgttacgtt gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc
     1501 gacagttgcc agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag
     1561 gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa
     1621 cgaatatcga agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat
     1681 gtacagatgt gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag
     1741 aagtagccat cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa
     1801 aatatccacg agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc
     1861 accaaatggg cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc
     1921 gctttagttc aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg
     1981 cactgagagt gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt
     2041 ctgaagcact ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac
     2101 gtccagaaag taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga
     2161 tcactggaga tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg
     2221 atccgtcaga agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg
     2281 cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg
     2341 tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg
     2401 caccagcgtt gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg
     2461 cgcaaagtgc cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg
     2521 tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct
     2581 gtaatatttc ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat
     2641 ttacagctgt gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt
     2701 taggaagaga gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag
     2761 ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg
     2821 taaccttgtt tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg
     2881 caagtcagca tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc
     2941 atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag
     3001 ctttggtaga aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat
     3061 ttacgcaaga actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga
     3121 ttttatctat cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag
     3181 cagaagaaga ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca
     3241 aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc
     3301 ttttactgcc tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc
     3361 tcttttaaat atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg
     3421 ggctgagcca tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa
     3481 atgaaagatc taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag
     3541 tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa
     3601 aatagctttg agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc
     3661 ataatgttgt aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac
     3721 ctttgaatcc acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa
     3781 tatcaagata agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa
     3841 ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg
     3901 atccatcata tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag
     3961 caataccaat caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta
     4021 gactctcttt tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt
     4081 ctttaataac accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt
     4141 ttttgttatt cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg
     4201 agggaacttg caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta
     4261 tatagaaagt agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag
     4321 aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac
     4381 caatgttcat gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga
     4441 aagaaatggg tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg
     4501 aagacttagt agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt
     4561 taacagattc aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag
     4621 aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag
     4681 caatcaacat ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac
     4741 cattcgatga aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag
     4801 aacgaggatt gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag
     4861 gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc
     4921 ctggttactc aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat
     4981 tagaattcac tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg
     5041 ctgctgattc attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc
     5101 ctactcgaat cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa
     5161 atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta
     5221 aaaactatac acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc
     5281 gtttgacttc ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag
     5341 caatcatgga tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca
     5401 ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag
     5461 tgttatcagc atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa
     5521 aaatgggaac attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta
     5581 tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac
     5641 caggtgattc agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg
     5701 acaaacggac agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa
     5761 tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa
     5821 cagaagaacc agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga
     5881 cagaagagaa ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa
     5941 gatgtcctac ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct
     6001 caatattgaa taatcgggtg tgtcatataa ataataataa ataactttat atatttttct
     6061 atacaaacac ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca
     6121 aaaaagtgtt tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa
     6181 taaccatgac ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag
     6241 acaattgacg tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa
     6301 gaaatggaaa gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca
     6361 gctttggatc aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt
     6421 tacgaagata aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa
     6481 catgataaaa cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct
     6541 gaaccagtcg gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt
     6601 ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt
     6661 gcccaaaaat cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga
     6721 gctcctgaaa attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta
     6781 atgaaccatc caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct
     6841 gcttactcta caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt
     6901 gaaaaaacag caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat
     6961 aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca
     7021 gtaaaagcag aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa
     7081 ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat
     7141 tctgcgatgg aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg
     7201 attgctgaat tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca
     7261 gttcttgcca tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg
     7321 ttgaatcttg gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat
     7381 gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa
     7441 ggcggcatcg gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct
     7501 tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact
     7561 gtagcgaaac ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa
     7621 aagaactctc tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt
     7681 gaccctggta tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt
     7741 aaaaatgatg tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc
     7801 gtatacgcag gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga
     7861 ggcggttctg caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca
     7921 tctttctttg gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac
     7981 aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta
     8041 acgccatttg cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat
     8101 gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct
     8161 gtcacagcag ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc
     8221 atggcttcag attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat
     8281 ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct
     8341 acaatggctg gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat
     8401 aaaatcggcg gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat
     8461 attatccgct ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat
     8521 ttccgtgcag atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca
     8581 acagaggaat tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc
     8641 atcaacatga gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac
     8701 cgtatggctg aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg
     8761 atctctgaat tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta
     8821 gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt
     8881 tttttaattt ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag
     8941 acagtttttg ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata
     9001 taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta
     9061 cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa
     9121 gacgataatg gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg
     9181 acagtgtgga attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg
     9241 acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa
     9301 ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat
     9361 gaagacacga aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg
     9421 aatgacatgc ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat
     9481 aagaatcagt tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg
     9541 aaactgttga atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc
     9601 aaatacttga tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat
     9661 cataactatg ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca
     9721 gagatcattg aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa
     9781 acacttgaag cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat
     9841 acgttgttgg atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac
     9901 ggtattttga aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat
     9961 cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca
    10021 atcgggacag gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg
    10081 ccttatggac agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa
    10141 aagaaaggaa acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct
    10201 aggtctgcta ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc
    10261 agatgtaaat gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat
    10321 tgatgcaatg aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat
    10381 ccagtatttc ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc
    10441 aggagcagta gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta
    10501 ttcgattttt tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga
    10561 taatgaagaa ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt
    10621 gacctattat gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc
    10681 ggaagatttg gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt
    10741 agagctttta ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca
    10801 atccaatttg atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg
    10861 tggtgtggct aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat
    10921 gaatgatgcc atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc
    10981 gaaagaatca acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc
    11041 tttagcacaa gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga
    11101 ggcagttgcc ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca
    11161 aaagatccaa gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag
    11221 atcctgggag ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc
    11281 agaacggttt taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc
    11341 tggtttgcca tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg
    11401 gttttaagtg aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt
    11461 ttatttctgg tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg
    11521 acaatggggc agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta
    11581 cctgtatcgg gggtactcat cattatctat agcctgatca atctaatcga tacattaagc
    11641 aacaagccag caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc
    11701 ggattagtgt tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata
    11761 agtattgcat tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct
    11821 tttagttcag ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg
    11881 tttttcgttc tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat
    11941 tttgcgatgt tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg
    12001 aatgctttat ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga
    12061 gtgttgatcc ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat
    12121 atcgcgtcag ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca
    12181 cttgttgctg gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct
    12241 ttgtgggcgc taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct
    12301 gttgtcgaaa aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc
    12361 cttctattga ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa
    12421 gcttcagcga tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta
    12481 aaactaaaag atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg
    12541 ttcttattgg ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag
    12601 gcaattagtt cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc
    12661 aatcttgtgt tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt
    12721 acaccaatat ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg
    12781 ttttcaatca tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat
    12841 gtcggtgcaa gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt
    12901 tatggggtta tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg
    12961 ctacccaata tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga
    13021 tctttccgaa gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca
    13081 tacactgcag ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat
    13141 caattctggg atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg
    13201 aattttaagt tgctatatca atatgattca tccagattta acgatacgac aagagttgct
    13261 gacaaagttc gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc
    13321 ggaaactgga tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc
    13381 atttgctgaa gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat
    13441 gatggtgggg atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca
    13501 gctgatccaa gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat
    13561 cacaagtagt gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg
    13621 tgaaaagata tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc
    13681 ggtaaatttg ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa
    13741 tcgtccgtac ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag
    13801 aagtcttctt gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc
    13861 ggggctagaa gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt
    13921 gattacaaaa aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac
    13981 atgctccaaa agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa
    14041 atctatcatg tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc
    14101 tatgagatcc atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt
    14161 acgatcaaag caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc
    14221 caatcttcag atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt
    14281 cgttccacgc catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt
    14341 cgtgtattgc aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct
    14401 cctgataaaa aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg
    14461 atttttctca atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt
    14521 cctaatgagc gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt
    14581 tctttagagg aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt
    14641 aaaaagtaca ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc
    14701 aagcacttgt tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct
    14761 tcttatccgc attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt
    14821 ttgaaacgtg atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga
    14881 gaatgatcac taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc
    14941 ggttatttta tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat
    15001 atgaatcagc tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg
    15061 cggctaaagt aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat
    15121 tctgtatacc gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt
    15181 ggtggagaac cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat
    15241 tgttgttcta attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc
    15301 agtttgtaaa cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa
    15361 atcagttcat tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc
    15421 gtgccttgtt gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga
    15481 tcccctgttg aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg
    15541 acgttctgac cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga
    15601 taacgctgat attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga
    15661 ttatcattat atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt
    15721 aaatgtgctc gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata
    15781 taaaaaaata aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc
    15841 gaccatgagt ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat
    15901 aatgcaatta tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca
    15961 ttgttaataa atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg
    16021 tggagaaatg aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat
    16081 gaaaagtacg agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa
    16141 cggctttcgg aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat
    16201 tttgattgga tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga
    16261 tacatgggca gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat
    16321 tgcttatcgg gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct
    16381 agataagttg tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt
    16441 gtttgctgaa gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta
    16501 tttagggtat gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca
    16561 gctgctgaat gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc
    16621 gaaggaatta tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga
    16681 acaattttca aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac
    16741 ggcgtcagct gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg
    16801 gacatggtcg cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc
    16861 tgaaaattat acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat
    16921 ggggatgtgg ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga
    16981 attggcagag cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc
    17041 tcgatttttg aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga
    17101 gcagccagtc cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctct
    17161 ttgttacgca caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct
    17221 gcacatcgta gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc
    17281 cggaatcatt gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca
    17341 aatgctcagt acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc
    17401 gtttccatgt gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt
    17461 gaataaaatc aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa
    17521 gaaaaatatg caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc
    17581 aaaatttcta tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc
    17641 gaattgaccg gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa
    17701 gagcttagac aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac
    17761 cttcatgcta tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa
    17821 cattttgaaa aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg
    17881 actttctttt cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa
    17941 gttcgtgaat actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg
    18001 aaagaaactg ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat
    18061 ccgattgatc gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca
    18121 gaagagttag atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc
    18181 gctgaagctt atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac
    18241 aaacttgttt gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta
    18301 tcttcattag ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg
    18361 gattcagacc atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc
    18421 cgtaacgaat tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac
    18481 cgtatcgctg cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg
    18541 ctggaaccag ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg
    18601 gcttatacgg aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac
    18661 aaaaatcaag ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac
    18721 gtgttggaat taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc
    18781 gccttatgtg aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga
    18841 aagaaatggc gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga
    18901 tcctgaaaaa gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg
    18961 ctattttatt gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga
    19021 gaatcttgga atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct
    19081 ggaaaacgaa tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg
    19141 tttagaagta gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc
    19201 gatgagtttt acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg
    19261 tacggaatgc ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg
    19321 aacaaatgag attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg
    19381 gccacaacat ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga
    19441 gacagcagaa aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca
    19501 aacaatcacg gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc
    19561 aggttatttg gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt
    19621 gcatgaaagt ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc
    19681 cagaaatgcg tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc
    19741 cgagtacaag tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa
    19801 tggcaaatac atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa
    19861 atccagatgc ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag
    19921 caactgggca accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt
    19981 aggaggaata gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag
    20041 gagcgattga gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca
    20101 ttactgacaa aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata
    20161 aagcagcaat cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg
    20221 taaaagatgg agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg
    20281 gaggttcgcc aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt
    20341 cagacgtcat tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag
    20401 ctataccaac gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg
    20461 aagtaaatca ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca
    20521 tcgacagcga tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg
    20581 ctatgacgca tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc
    20641 tgcatttaaa agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc
    20701 aaaatgggcg agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg
    20761 tcggtttagg actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc
    20821 atggcgtagc gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg
    20881 gagaaaagta ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt
    20941 tagaagatgt aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa
    21001 tcccagaaac catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag
    21061 atgctttgcg agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca
    21121 ttgctttata tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt
    21181 aaagagaaat ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata
    21241 atttttctta taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg
    21301 tattgatcaa agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc
    21361 agacgatcgc aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt
    21421 tgttgatgat cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc
    21481 ttattcgcta cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt
    21541 ttttagaaca gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca
    21601 atgagatctt gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa
    21661 aaatcggaat cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat
    21721 tcagtgaaga gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat
    21781 atacgatcac caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca
    21841 tcgcatttga cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga
    21901 aaaacgaaca aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg
    21961 agacaaaaga acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa
    22021 ttcaaaaata atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata
    22081 gatttccaag ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa
    22141 ttgatatttt atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca
    22201 aagaagaagc tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt
    22261 tgacttttac agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag
    22321 accaaccaga aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg
    22381 ctatcttagc tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga
    22441 tgtgcaatct gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa
    22501 cagcgctgaa aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa
    22561 gtatcatttc tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg
    22621 tgagtctgga caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg
    22681 ggaacctttt agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac
    22741 agtatgcagc aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac
    22801 tcggagaaat catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac
    22861 gattcgctgc ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg
    22921 gacatgaagc gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa
    22981 agcacttgca atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag
    23041 gtacttatta tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg
    23101 ccggatcaag ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag
    23161 gaatagatat atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa
    23221 tgacgaaaca ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca
    23281 actatcgtgg aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac
    23341 ctttagtaga tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga
    23401 aagcgccaga agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt
    23461 tcccgaatat tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg
    23521 aattgaaggg gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca
    23581 ccccaatcgt ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga
    23641 ttttatccaa tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga
    23701 agcatacgat ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag
    23761 catgcggctc tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa
    23821 cacgttatac acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag
    23881 aatttttagt agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg
    23941 atcgaatgat ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca
    24001 aagaactagg tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg
    24061 gaccaggatt catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact
    24121 atatcggaaa agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta
    24181 aattctatat tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg
    24241 accaagtaaa accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc
    24301 aatacatcca tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag
    24361 aaccaggaag cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    24421 atgtctactt tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag
    24481 atgaaacaaa acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga
    24541 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    24601 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    24661 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    24721 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    24781 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    24841 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    24901 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    24961 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    25021 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    25081 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    25141 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    25201 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    25261 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    25321 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    25381 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    25441 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag
    25501 gttgtgaaat cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    25561 gaaaaaagag gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa
    25621 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc
    25681 cgtttgtacg tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt
    25741 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    25801 ggtccggaaa agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    25861 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    25921 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga
    25981 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    26041 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    26101 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    26161 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    26221 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt
    26281 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    26341 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg
    26401 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    26461 tgtcgcataa tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa
    26521 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    26581 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    26641 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    26701 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    26761 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    26821 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct
    26881 ggtcaacaat tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt
    26941 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    27001 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    27061 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta
    27121 agaaaagctg ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat
    27181 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    27241 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    27301 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    27361 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    27421 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    27481 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    27541 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    27601 catacttttc agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    27661 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    27721 attggatact tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg
    27781 cagcgataac tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt
    27841 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    27901 gaccagcatg tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    27961 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    28021 agtagcatgg aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt
    28081 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    28141 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    28201 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    28261 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    28321 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    28381 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    28441 cagacccgcg tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag
    28501 tattgcaagc gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    28561 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    28621 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta
    28681 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    28741 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    28801 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    28861 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    28921 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    28981 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    29041 aaatcattgc tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc
    29101 aacgtttctg gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    29161 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    29221 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    29281 ttcaaagaaa agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    29341 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    29401 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    29461 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    29521 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    29581 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    29641 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    29701 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    29761 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    29821 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    29881 cactaagggt ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa
    29941 ctaagaatac gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttttt
    30001 cttctttgac tagaaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    30061 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    30121 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    30181 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    30241 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    30301 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    30361 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    30421 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    30481 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttggagcgt atcgaaaaac
    30541 gtggtcgttc gtatgaacaa ttgtcctttg atccaagtct atacgattat tacaaagaat
    30601 tgaacagacg ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    30661 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    30721 tcgaagaaaa attagcagag attcgccaaa ccaaagtagc catttgattt acagttgctc
    30781 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    30841 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    30901 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    30961 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    31021 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    31081 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    31141 ataccgagta cgtgattcga ctaattcgat cgcttttgga acgaatgcca gacatgagtg
    31201 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    31261 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    31321 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    31381 aacaaaatgt agtactttta gaacaaatca aggcattggc tatttatcgc aagttgtcag
    31441 aaaaggaaaa agaagagttg gacgatgcgc tgatcgaagc acgacaagca gttgaaatga
    31501 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    31561 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    31621 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    31681 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    31741 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    31801 tgcttgctct tggttgacga ttagtcccgc caaagaatct tgagataaag cgattgctgt
    31861 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    31921 caactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    31981 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    32041 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    32101 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    32161 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa ctgttttttg
    32221 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    32281 ttggtcaccc ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    32341 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    32401 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagt ctgctaatct
    32461 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    32521 tgctatacta tgatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    32581 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    32641 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    32701 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    32761 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    32821 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    32881 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    32941 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    33001 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    33061 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    33121 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    33181 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    33241 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    33301 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    33361 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    33421 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    33481 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    33541 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    33601 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    33661 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    33721 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    33781 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    33841 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    33901 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    33961 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    34021 aagtctaaaa tagcataatt aaggtttttt aattgaaaac tgaacattta tggtcaccct
    34081 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    34141 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    34201 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    34261 tttgccatca tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca
    34321 aacccggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg
    34381 ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt
    34441 gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg
    34501 gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg
    34561 atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccaat cttgatgtca
    34621 ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc
    34681 tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg
    34741 gctgaaagct atacttataa tgactatttc caaattggta tgattgggat gattgtaagc
    34801 ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg
    34861 gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta
    34921 ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca
    34981 ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt
    35041 cagtttgcga aattatttac agatggcgca gtagatgttg caccaatggt tggtttcttg
    35101 atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt
    35161 tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca
    35221 ccactaggat ttttccgcgg tccaatgaat ctagtcggtt caggctcagc tattttagct
    35281 gtcgtattag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatc
    35341 acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt
    35401 tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc
    35461 ggagcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt
    35521 cgataaaaac gattagatga atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa
    35581 ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca
    35641 tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg
    35701 ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg
    35761 ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg
    35821 gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat
    35881 tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg
    35941 tcaaacactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag
    36001 cggaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg
    36061 tttatgaagc agcatcggta aaatcgatcc ctacaacgat ggcttctgac atcacaaaat
    36121 tatatggatt gacaagaaga actcggacag cagcaatcaa tgcatctatt ttaccaaaaa
    36181 tgctagatac ggcaacctct acagaagatt ccgtacgaga agcaggggtc aatgtttctt
    36241 tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg
    36301 ttttaaccat gctttccggt ccagcagcat cagtcatggg ctctttgatg tacttgagag
    36361 cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa
    36421 atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat
    36481 tagatgttcg ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa
    36541 tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg
    36601 agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg
    36661 ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg
    36721 cagccaatgt ccttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg
    36781 cacgaaaagc catccaagca ttagctgatt attgtcatac gacggttgaa gacatcgcag
    36841 aacagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca
    36901 agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat
    36961 tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag
    37021 tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc
    37081 cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg
    37141 aatcaggcgc tacaccagaa tcgatcgaag tccacgtaga aatcgatcca cagacttcaa
    37201 aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga
    37261 tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag
    37321 tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa
    37381 atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg
    37441 cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag
    37501 atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag
    37561 caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg
    37621 aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa
    37681 cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc
    37741 taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt
    37801 atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct
    37861 tttgccgatg taggagaaat ttgtgaacaa atggctgttc caatcgtttc ctgtgaatca
    37921 gagcaaataa acgaacgaat cacttttgca acttatgcag aagatgaagg gattcgattg
    37981 atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca
    38041 gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga
    38101 atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca
    38161 aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc
    38221 gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc
    38281 caagggatct tagaagaaat aaaaaaaata gaaaaaagat gtacggagta tgatttagat
    38341 tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacgat
    38401 gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt
    38461 tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaacg
    38521 gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca taagaagcta
    38581 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa
    38641 acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa
    38701 ctattttgcc gtttctttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat
    38761 ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct
    38821 tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta
    38881 tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat
    38941 tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc
    39001 caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc
    39061 aaatcaaaaa aagctttttt attttgagcg attactgcct gatcggtttt tccaactttt
    39121 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
    39181 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
    39241 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
    39301 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
    39361 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
    39421 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
    39481 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac
    39541 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
    39601 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
    39661 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
    39721 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
    39781 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
    39841 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
    39901 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
    39961 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
    40021 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
    40081 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
    40141 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
    40201 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
    40261 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
    40321 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
    40381 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
    40441 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
    40501 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
    40561 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
    40621 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
    40681 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
    40741 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
    40801 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
    40861 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
    40921 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
    40981 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
    41041 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
    41101 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
    41161 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
    41221 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
    41281 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
    41341 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
    41401 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
    41461 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
    41521 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
    41581 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
    41641 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
    41701 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
    41761 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
    41821 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
    41881 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
    41941 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
    42001 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
    42061 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
    42121 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
    42181 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
    42241 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
    42301 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
    42361 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
    42421 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
    42481 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
    42541 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
    42601 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
    42661 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
    42721 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
    42781 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
    42841 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
    42901 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
    42961 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
    43021 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
    43081 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
    43141 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
    43201 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
    43261 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
    43321 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
    43381 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
    43441 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
    43501 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
    43561 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
    43621 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
    43681 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
    43741 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
    43801 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
    43861 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
    43921 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    43981 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    44041 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    44101 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    44161 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    44221 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    44281 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    44341 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    44401 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    44461 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    44521 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    44581 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    44641 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    44701 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    44761 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    44821 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    44881 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    44941 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    45001 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    45061 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    45121 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    45181 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    45241 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    45301 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    45361 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    45421 ttggataaat caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    45481 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    45541 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    45601 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    45661 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    45721 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    45781 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    45841 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    45901 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    45961 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    46021 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    46081 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    46141 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    46201 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    46261 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    46321 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    46381 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    46441 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    46501 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    46561 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    46621 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    46681 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    46741 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    46801 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    46861 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    46921 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    46981 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    47041 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    47101 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    47161 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    47221 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    47281 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    47341 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    47401 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    47461 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    47521 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    47581 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    47641 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    47701 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    47761 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    47821 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    47881 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    47941 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    48001 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    48061 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    48121 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    48181 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    48241 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    48301 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    48361 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    48421 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    48481 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    48541 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    48601 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    48661 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    48721 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    48781 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    48841 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    48901 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    48961 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    49021 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    49081 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    49141 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    49201 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    49261 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    49321 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    49381 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    49441 cgccttatca taagtgatgc ggtttttatc attgatccta aaaatcttag caagacaaaa
    49501 agtacgtaag aaagtaaaga ctaaatactt cggaggaaca aatgaataac aatgataggt
    49561 tattgcgatt gcgttatgcg attgatttga aagatacgga tttgattaaa gcttttgagc
    49621 taggcggtgt accactgact aaagaagaag ctcaggcggt actgaccaaa gtacaggata
    49681 agaacaaaga taatgcagaa aataatgtgt atgaaaaaac catcaacaac caagtttttg
    49741 acgcattcct aaatggcctg attctcttgg cgcgtggtcc gcaaaaagat aagccgatag
    49801 tagacacgcc gcaaaaaagc aaggaaatca aatatatcaa caatgtgttg ctaaaaaaat
    49861 taaaaatcgc cttgtctatg accactgatg atattttaga cgtttttgct gaggcagaaa
    49921 tctatccatc aaaaggcgaa atcggggcat ttttgagaaa agaaggccaa cgaaatttta
    49981 agccttgcgg agataaatat atgcgtaatt ttctcaaggg gttaggaatt tataatcgga
    50041 gaaaagtata aagaaatttc atgagaaatc aaaacaatgg ttgttttgat gagagctagt
    50101 ttttgtatga gattaaaata ttatcttaat cgaggagctg gattggtttt atgaatgatg
    50161 aatataagaa tgatgaagat aagatgcttt ttgaagagat agagaatcga tgtaggctca
    50221 attttgagct tcggggaaag atgtctttaa tacaacaaaa aaagtattta gcgaataaat
    50281 cagagtttac tctgggacat gttgaaaaat taatctcgga ttggattagt agtagaagcg
    50341 aatttacaaa aataaaacag ccgattaaat ttgacatgaa aaaacttttg ttaaataaga
    50401 gtgagatagg taatagagat caatatatta gagctaaagg gcaagaaata attgattcat
    50461 taggtgaaat gaggtcatac aattatttgt atgtaacaca tagagctgat ggaatggtca
    50521 ttactgtggg gaaatcttct tctaatgata tttttttaga tggagatctt ttttatcaac
    50581 tcaatacaaa tcacttgtct ggcactgaaa atataatttt aaggacggaa tatggcaatg
    50641 aaatatttgc aaaatatgat gagattttaa aaaattattt ggactgggct tggataattc
    50701 cggttgagtc aggagatgct aagaaactgg agagattatt gggcgatgaa ctaattaata
    50761 aaaaagtacc aattttaaat tattattccc atagacaata aaaggctatt tttcatgata
    50821 atactagtta taactgtaaa aatggaagaa aatctgggaa agaagttttt aaataagtgt
    50881 attgttcgat tttaataaat aataagcaat accatccgtc tgtgttgcgc aacatcgtac
    50941 tacaatgaat attttttcac aaaaagaaaa tcatccatcg aatgaatgga aggttttagt
    51001 atacacgagg ttaatgcccc ctcttttata atcagaggag tgaggttttt tctatgaatg
    51061 tttctatttt cttattgcta gtctagtttc tcttacgatg aaattgggat tctattccag
    51121 tttttattga tttgctgata aaataacttg aatggtggat ataaacatga taaataagag
    51181 aagaataaca aaacaaggtt gtgaaatgat tctcaaatga atataataga aagaaaaagg
    51241 aggaagaatc aatgaaaata gcaattgcag gcgctggcgc aatgggaagt cgctttgggt
    51301 taatgcttca ccaaagtggg aacgaagtat tattaatcga tggctgggca gaacatgtcc
    51361 aacaaatcaa agagcatgga ttacaagcaa attttaatgg taaagaggta gaagcaaaac
    51421 taccaatcgt tcttcaatcc gaagtagaaa aagaagatca agttgatctg attattctat
    51481 ttaccaaagc gatgcagctg gaaaaaatgc tgcaggatat ccaatcatta atcaaaaaag
    51541 atacagaggt cttatgtcta ttaaatggta tcgggcatga agatattatt gagaaatttg
    51601 taccaatgga aaatatctat attggaaata ccatgtggac ggcaggtctt gaaggtcctg
    51661 gtcaggtcaa attatttgga agtggttcag tagaattaca aaatttaggt gatggaaaag
    51721 aagcagctgc aaaaaaatta gcagacaaat tgtctgaatc aggattaaat gctcattttt
    51781 ctgacaatat tcactattct atttatcgca aagcatgtgt gaacggaaca atgaacggac
    51841 tatgcacaat cttagacgtt aatatggctg agctaggaaa aacatcgact gctcataaaa
    51901 tggtggcgac gattgtcaat gagtttgcca aagtagcagc agtagagaag attgaactag
    51961 atgtcccaga agtcattgca cattgtgaat cttgttttga cccggaaaca attgggttac
    52021 attatccttc aatgtatcaa gacttgatta agaaccatcg attaacagaa atcgattata
    52081 tcaatggcgc aatttctaga aaagggaaga aatatggtgt tgcgacgcct tattgtgatt
    52141 tcttgactga gcttgtccat gcaaaagaag atagtttgaa cgtaaaataa aggagagatt
    52201 gaatggaaac ttcacaaaaa atatcaccga aaatttttct gaataaagtc ctcgctggta
    52261 cagcaacagg aatcattatt ggattgattc ctaatgcagt attaggtgcc attttaaaat
    52321 attttagtgc gtatcccttt gcggtaacga tcgcacagtt agcagttatt tttcaactag
    52381 caacaccttt gatcattggt ggtttgattg ccttacaatt tggatttgat ccgatgagaa
    52441 tgatggttgt agccggagct tcttttgttg gttctggtgt agtcaaattc acacctgatt
    52501 tgggtgaaac gggtgtttac gttggtgctg gtacaggcga tattattaat acgatgctga
    52561 cagcatcgat tgctgtcggg ctgattttac tgattggaaa tagttttggg tcagtgtcga
    52621 ttgtgttaac accgattgtt gtaggtgtag gtgcaggttt acttggtttt tatttattcc
    52681 cttttgtaac agcaattact tctgcaattg gatcattgat taataacttc actaccttac
    52741 aaccgctgtt aatgtctatc ttgattggtt gttcctttgc ctttttgatt atctctccta
    52801 tttcaacagt agcaatcgga atggcaatcc aactagatgg tgtttctgct ggtgcggctg
    52861 cgatgggcgt agctgcaacc acttttgttt tagtagtgaa ctcttggaag gttaataagt
    52921 caggtgtgac aattgcgatt gctttaggcg ctatgaagat gatgatgcct aatctattta
    52981 gaaaacctgt gattcttatt ccttgtttag ttagtgcagt gattacagct attcctgtcg
    53041 ctctattttc tatttcaggt acgcctgctt ctgctggttt cggcgtggtc ggacttgttg
    53101 gtccgttggc ttctttagat gcagggctaa atggctttct tgttgttctt tgttggttag
    53161 tcatccctgt ttttgcggca ctaattactc aatttttatg cgagaaagta tttaaactgt
    53221 atgatcgaga agaagtcttc aaatttttag gctagtagat tttactaaga aattttcaat
    53281 caatggatgc gtaagtgaga tgtcaacaac atctgactta cgtttttttg cctttttgag
    53341 taggagattg atgctgacaa ctgaactctt cagtgccatt cgatttttta aaatgtagaa
    53401 gaaactcacc tttatgttat tgattgttca aaaggcaact agaataaaaa tatgtgttaa
    53461 aatgagaaaa aatttgattg ttggatgtat cgaataatca ctaaaaagta ggagaagaaa
    53521 atgatttttt tgcaaaaata tggtttttat tttttattat taggtgtgat tagtgattta
    53581 tcgacaccgt atatccttgg ccttttttat cccaaactga atcaaatgac taccgtaatt
    53641 agtgtgtttg gtgacgtaga tagtccagtc agacgtgctt tcttggtctg gtcagttgta
    53701 tctggacttt tttttgttct ttcgttgcct gcgttgtatc acctatttat tggaacatca
    53761 aaaacacttg caatacttgc tgttgcaaca gttggtttat atgggatagg tgattgtatt
    53821 tttactgggt tattcagtat caatacgaat gaaagctctt ggaatctatc gacttggatc
    53881 cataatatag gttctgggct aggctatgca ggctttctac ttttcccatt gttacttgtt
    53941 ctgctttatc gtcaaagtgg tcaaggtacg cttagccatt tttatcttgt tttaacagtt
    54001 attagtttac taattgcagg tctttacgga ttagcacgga ttccgtcgat tagtcagttt
    54061 gccttcttta agcaattggg cttctttcaa cgcttaagtt ttttctttaa ctatttgccg
    54121 atgatttgtt taagtttttt tcaactacga aagtagaaaa agcagtgtga agctgattaa
    54181 gtaaaagaat ttctctatgg gtaaccattc gtgtggatgt gttcgactaa gaatagagat
    54241 gaggagagcg aaaagcaagt tagtcttaac ttgttatgcg ttgtgctaaa tttcaggtag
    54301 tcattttttg aatgaataag aagaaaactt gaaagagggt gacttcatgt tagatgtgga
    54361 gcagatggaa atagaccttt ataatattat tttaaatcga aatacaagag aatgggaaag
    54421 aacacaattt gaagaggcaa aagaagacct agcaaaaatg tcgataaagc aggtgataga
    54481 aaaactagag gtcaacttgc gtccgctagc actacgagat aatttgacac cagatgcgat
    54541 ggatttttat ttaagaatca caggggagtc agcgagtgca aaggcttatg attatgccaa
    54601 acataagata acttcaccct tataccaaga acgggcgatt tttgccggtg gctgtttctg
    54661 gtgtatggtt gagccttttg aaacaaaacc aggtgtaatc tcagtgttat ctggttatac
    54721 aggtggagag accaaaaaac caaattacga tcaagtcagt ggtggatata ctgggcatgt
    54781 tgaagctgtt gagatcatat ttgatacacg tcaaataacc tatgaagagc tgttggagat
    54841 ttattggcaa atttcagacc ctacagatgc ctttggtcaa tttcaagatc gggggaaaca
    54901 atatcgttca attctatttg ttgttaatga aaagcaaagg caattggctg aaaaatcaag
    54961 agaacaactg attcaatcta accgatttag ccgtcctatc gttacagaga ttcgccaagc
    55021 aaagactttt tggccagctg aaaatcatca tcaacaattt tatcagaagc aacctaaaag
    55081 atataaaaag atcaagcatt cgcatcagct tcatttattt tttcagcgac atagatagag
    55141 gaaggttgtg gcgcaaagcg ttcagctccg acaaaataat gagcaactga caaaaatagc
    55201 ttttcatatt tttggacagt tatgaattat ttcgaggagt tgctttgaga acaccgagga
    55261 aaaggttgtg gcgcaaagca ttcagcttca agtcgcaagg aaacaggagg tatgacaagt
    55321 cttttgtcac aactcctgtt tttttactag cctttatttc catgtgaaag agaattcgaa
    55381 ttgtagaatc ttgatttttc tatggaattt tgtagagaat catcttgata attaatagac
    55441 acctaatcga attccacatt aatgatgaac taaattccgt ataaaagcgc aaacaataac
    55501 ta
//
LOCUS       DBBGRF010000014        54445 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000014 DBBGRF010000000
VERSION     DBBGRF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 54445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.014"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..587
                     /locus_tag="ACIZD4_000935"
     CDS             <1..587
                     /locus_tag="ACIZD4_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989887.1"
                     /translation="LDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFG
                     NTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIV
                     GIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAV
                     KELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(827..910)
                     /locus_tag="ACIZD4_000936"
     tRNA            complement(827..910)
                     /locus_tag="ACIZD4_000936"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(874..876),aa:Leu,seq:gag)
     gene            983..1144
                     /locus_tag="ACIZD4_000937"
     CDS             983..1144
                     /locus_tag="ACIZD4_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989888.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            1293..2510
                     /locus_tag="ACIZD4_000938"
     CDS             1293..2510
                     /locus_tag="ACIZD4_000938"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGC5989889.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2694..3530
                     /locus_tag="ACIZD4_000939"
     CDS             2694..3530
                     /locus_tag="ACIZD4_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989890.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3606..4754
                     /gene="nagA"
                     /locus_tag="ACIZD4_000940"
     CDS             3606..4754
                     /gene="nagA"
                     /locus_tag="ACIZD4_000940"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGC5989891.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            5032..6033
                     /locus_tag="ACIZD4_000941"
     CDS             5032..6033
                     /locus_tag="ACIZD4_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HGC5989892.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            6052..7071
                     /locus_tag="ACIZD4_000942"
     CDS             6052..7071
                     /locus_tag="ACIZD4_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HGC5989893.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(7173..7889)
                     /locus_tag="ACIZD4_000943"
     CDS             complement(7173..7889)
                     /locus_tag="ACIZD4_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC5989894.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7858..8643)
                     /locus_tag="ACIZD4_000944"
     CDS             complement(7858..8643)
                     /locus_tag="ACIZD4_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5989895.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8634..9383)
                     /locus_tag="ACIZD4_000945"
     CDS             complement(8634..9383)
                     /locus_tag="ACIZD4_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGC5989896.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9681..10205
                     /locus_tag="ACIZD4_000946"
     CDS             9681..10205
                     /locus_tag="ACIZD4_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HGC5989897.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10221..11720
                     /locus_tag="ACIZD4_000947"
     CDS             10221..11720
                     /locus_tag="ACIZD4_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HGC5989898.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11808..12410)
                     /locus_tag="ACIZD4_000948"
     CDS             complement(11808..12410)
                     /locus_tag="ACIZD4_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC5989899.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12514..13470
                     /locus_tag="ACIZD4_000949"
     CDS             12514..13470
                     /locus_tag="ACIZD4_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGC5989900.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13775..14731)
                     /locus_tag="ACIZD4_000950"
     CDS             complement(13775..14731)
                     /locus_tag="ACIZD4_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC5989901.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14905..15465
                     /locus_tag="ACIZD4_000951"
     CDS             14905..15465
                     /locus_tag="ACIZD4_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989902.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15458..16282
                     /locus_tag="ACIZD4_000952"
     CDS             15458..16282
                     /locus_tag="ACIZD4_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HGC5989903.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16292..16909
                     /locus_tag="ACIZD4_000953"
     CDS             16292..16909
                     /locus_tag="ACIZD4_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HGC5989904.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16927..17610
                     /locus_tag="ACIZD4_000954"
     CDS             16927..17610
                     /locus_tag="ACIZD4_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HGC5989905.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18293..19576
                     /locus_tag="ACIZD4_000955"
     CDS             18293..19576
                     /locus_tag="ACIZD4_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5989906.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19592..20479
                     /locus_tag="ACIZD4_000956"
     CDS             19592..20479
                     /locus_tag="ACIZD4_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5989907.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20496..21332
                     /locus_tag="ACIZD4_000957"
     CDS             20496..21332
                     /locus_tag="ACIZD4_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5989908.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21335..21958
                     /locus_tag="ACIZD4_000958"
     CDS             21335..21958
                     /locus_tag="ACIZD4_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989909.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21955..23247
                     /locus_tag="ACIZD4_000959"
     CDS             21955..23247
                     /locus_tag="ACIZD4_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC5989910.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      23606..23703
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23819..24400
                     /locus_tag="ACIZD4_000960"
     CDS             23819..24400
                     /locus_tag="ACIZD4_000960"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGC5989911.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24403..25710
                     /locus_tag="ACIZD4_000961"
     CDS             24403..25710
                     /locus_tag="ACIZD4_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGC5989912.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26126..26614
                     /gene="purE"
                     /locus_tag="ACIZD4_000962"
     CDS             26126..26614
                     /gene="purE"
                     /locus_tag="ACIZD4_000962"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGC5989913.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26607..27731
                     /gene="purK"
                     /locus_tag="ACIZD4_000963"
     CDS             26607..27731
                     /gene="purK"
                     /locus_tag="ACIZD4_000963"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGC5989914.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27744..29039
                     /gene="purB"
                     /locus_tag="ACIZD4_000964"
     CDS             27744..29039
                     /gene="purB"
                     /locus_tag="ACIZD4_000964"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGC5989915.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29219..29596)
                     /locus_tag="ACIZD4_000965"
     CDS             complement(29219..29596)
                     /locus_tag="ACIZD4_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989916.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29852..30580
                     /gene="purC"
                     /locus_tag="ACIZD4_000966"
     CDS             29852..30580
                     /gene="purC"
                     /locus_tag="ACIZD4_000966"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGC5989917.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30580..30834
                     /gene="purS"
                     /locus_tag="ACIZD4_000967"
     CDS             30580..30834
                     /gene="purS"
                     /locus_tag="ACIZD4_000967"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HGC5989918.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30836..31507
                     /gene="purQ"
                     /locus_tag="ACIZD4_000968"
     CDS             30836..31507
                     /gene="purQ"
                     /locus_tag="ACIZD4_000968"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HGC5989919.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31508..33730
                     /gene="purL"
                     /locus_tag="ACIZD4_000969"
     CDS             31508..33730
                     /gene="purL"
                     /locus_tag="ACIZD4_000969"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HGC5989920.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33715..35154
                     /gene="purF"
                     /locus_tag="ACIZD4_000970"
     CDS             33715..35154
                     /gene="purF"
                     /locus_tag="ACIZD4_000970"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGC5989921.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35177..36229
                     /gene="purM"
                     /locus_tag="ACIZD4_000971"
     CDS             35177..36229
                     /gene="purM"
                     /locus_tag="ACIZD4_000971"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGC5989922.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36226..36804
                     /gene="purN"
                     /locus_tag="ACIZD4_000972"
     CDS             36226..36804
                     /gene="purN"
                     /locus_tag="ACIZD4_000972"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGC5989923.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36801..38336
                     /gene="purH"
                     /locus_tag="ACIZD4_000973"
     CDS             36801..38336
                     /gene="purH"
                     /locus_tag="ACIZD4_000973"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGC5989924.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38352..39626
                     /gene="purD"
                     /locus_tag="ACIZD4_000974"
     CDS             38352..39626
                     /gene="purD"
                     /locus_tag="ACIZD4_000974"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGC5989925.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39748..40662
                     /locus_tag="ACIZD4_000975"
     CDS             39748..40662
                     /locus_tag="ACIZD4_000975"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGC5989926.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40795..42360)
                     /locus_tag="ACIZD4_000976"
     CDS             complement(40795..42360)
                     /locus_tag="ACIZD4_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989927.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42353..43804)
                     /locus_tag="ACIZD4_000977"
     CDS             complement(42353..43804)
                     /locus_tag="ACIZD4_000977"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC5989928.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43818..44834)
                     /locus_tag="ACIZD4_000978"
     CDS             complement(43818..44834)
                     /locus_tag="ACIZD4_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5989929.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45054..46142
                     /gene="chvE"
                     /locus_tag="ACIZD4_000979"
     CDS             45054..46142
                     /gene="chvE"
                     /locus_tag="ACIZD4_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC5989930.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46196..47722
                     /gene="mmsA"
                     /locus_tag="ACIZD4_000980"
     CDS             46196..47722
                     /gene="mmsA"
                     /locus_tag="ACIZD4_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC5989931.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47724..48929
                     /gene="mmsB"
                     /locus_tag="ACIZD4_000981"
     CDS             47724..48929
                     /gene="mmsB"
                     /locus_tag="ACIZD4_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HGC5989932.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49186..50163
                     /gene="guaC"
                     /locus_tag="ACIZD4_000982"
     CDS             49186..50163
                     /gene="guaC"
                     /locus_tag="ACIZD4_000982"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGC5989933.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50427..51851
                     /locus_tag="ACIZD4_000983"
     CDS             50427..51851
                     /locus_tag="ACIZD4_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGC5989934.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(51893..52150)
                     /locus_tag="ACIZD4_000984"
     CDS             complement(51893..52150)
                     /locus_tag="ACIZD4_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989935.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            52312..53421
                     /gene="pdhA"
                     /locus_tag="ACIZD4_000985"
     CDS             52312..53421
                     /gene="pdhA"
                     /locus_tag="ACIZD4_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HGC5989936.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53424..54401
                     /locus_tag="ACIZD4_000986"
     CDS             53424..54401
                     /locus_tag="ACIZD4_000986"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGC5989937.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT        17400 a         9316 c        11922 g        15807 t
ORIGIN      
        1 ttttagacat gaatatctta tttttattgc tatttttctt aattttcctt ctaacatata
       61 ggaaatgtca aaactattat gtgcgtatat tgactgcatt accgtttttc ttaaacctga
      121 ttatttattt tggtaataca atgggtcaaa gctttactta cgtcaatgga aataaaaggg
      181 caatgatttg gagtagtagt aacctgaata atctctttac agagttagga acgaaactgt
      241 cactttttta tccaggtact tggatagcta ctttagtagt cttggcatta ttactatgtt
      301 taattgttgg aatttattta agttttgaca ataagaaaac ttctattttt ttagttattt
      361 tgatgataat gggattttgt tcaaggttaa ttatgggatt ttctcccaca gtatgggctt
      421 ccggaatgcg gacgtactat atactttatg ttgttatcgc catcttagta ctaatggcag
      481 ttaaagagct aatgaaaagc atgagtgtac aaaaaaatga atttatgcaa tttggattaa
      541 ccgtgcttgg tatttgtacc tttataataa cggtgataaa cagataatat acaaaaaatc
      601 cctcgcttta gtattaggtg agggatttta ctcgtttttc gattaattgt tttaacactt
      661 gcaagtttct acgagtagct tgtttccgac cttcatatac tcacctcagg ctgtttacat
      721 gattgtacgt tctttttgta aaggatacag tgatatgtat ataatggcat aaagaaacgt
      781 tcaaacaaaa aaactcgtga agcaaaatta acttcacgag ttgtagtgca gatgatggga
      841 ctcgaaccca cacgagctaa cgctcacatg accctcaatc atgcttgtct gccaattcca
      901 acacatctgc gtaataataa cacactaatg atagcgaggt tttacatagt tgtcaagctc
      961 aaaaatggga ggacttatta agatggagaa atatgacgga gaattttcag gactgggaat
     1021 gatcttaggt gtattgattg gacttgcatt cggacgtttt ttgcttggtt ttatgctagg
     1081 aatcatttgt ggaattgcaa tggattgggc agcgaatcta tggaatgact atcatgacaa
     1141 ttaagttctc aacgcttgtt tgtgtttttt taatacttac gtttttccta aataagtggc
     1201 aaaattttct aggatggagt atgatattga aatagtaaat aacaaaaaat ttggaaagtt
     1261 ctaacttttt gaaatgaggg attggctaag tgatgagaga atttgaaaaa tccaacaaat
     1321 tagaaggtgt cagttacgat gttcgcggtc ccgttctaga agaagcggag cggatgcaag
     1381 aagagggcat tagtatttta aaattgaaca cgggaaatcc cgcacctttt ggatttgaag
     1441 caccaaacga agtcattcgt gatttgatca tgaatgcccg tgactcagaa ggctactcag
     1501 attccaaggg gatcttttct gctagaaaag caattgagca atattgccaa ctgaaacatt
     1561 ttccgaatgt gacgatcaat gatatctaca ccggcaacgg agtgagcgaa ttgatcacga
     1621 tgtgtatgca ggggttgctg gacaatggag atgaagtact ggttccaatg ccggactatc
     1681 cgttgtggac ggcttctatt gcattagctg gaggcacacc tgttcattat atttgcgatg
     1741 aagaggcaga atggtatcct gatattgatg atatcaaatc aaaaataacg agtcggacaa
     1801 aagctattgt tatcattaat cctaataatc ctactggggc actttatcca aaagaattat
     1861 tagaagaaat cgttgaagta gctcgacaaa ataacctgat tatttattcc gacgaaatct
     1921 atgatcgctt agtgatggat ggtctagaac atattccgat tgctacatta gcgcctgatt
     1981 tgttcgttgt tacgctgaac ggtctatcca aatctcatcg tgtagcagga tttcgagtag
     2041 gctggatggt cctaagtgga gataagtcac acgtcaaagg ctatatagaa gggctgaata
     2101 tgttgtcctc catgcgtttg tgttccaatg tattgtctca gcaaattatc caaaccgcgc
     2161 taggcggtta tcaaagtgtc gatgagctgc tcctgccagg cggaaggatc tatgaacaaa
     2221 gagaatatat ctataatgca atcaatgata ttcctggtct ttcagccgta aaaccaaaag
     2281 ctgcttttta tatattccca aaaattgata caaagcgatt caatattttg gatgatgaaa
     2341 aattcgtttt ggacttttta catgaacatc atattctact tgtacatggt ggtggattta
     2401 attggaacca gccagatcat tttcgaatcg tttatcttcc taaaatggat gatttgaaac
     2461 aaacagctaa gaaaatgaga gaattcctag caacctatcg ccaaaaatga ttttaaaaac
     2521 caaatttttc agtaggaggg ccacagacaa acacactgag gctctctttc tagtggagtt
     2581 ttcttaaata actaaagtat attatttagt tgcaagtctt ttcttgaagt ttgcgacttc
     2641 ctaaagtaaa atacgaatag aatgcgaata cgcatatttt ggggaggata cttatggaaa
     2701 cgttaatcga gtcctttgga acgatcatta aagagattcg aaaagaacaa aaaatgacgc
     2761 aaaaaatgct ttcgcatgat atttgttcac aaagtgtatt aagtcggatc gaaaataatg
     2821 aggaactgcc gaatgtattg gtgatgatgc agatttgtca acggctaggg gtaacgattg
     2881 atcatgtgat gaatctctct cgaaaaacta ctcggacaaa cgataaatta tttgaactgt
     2941 tggatagttg tttccaaaaa cgtgattatc ggaagttaga acaagtacta aaatcttctg
     3001 atatttctga aaatctgtat caagcaactg actttcaacg ctattattat tatctcggtg
     3061 tttgcgaatt cacgttgcgt caaaatatct ctcagtccct ttattatttg aaagaagcat
     3121 taagctactc tagccaaaaa gaaagaatcc atgtttctga cacagaaata caactgatta
     3181 gttgtatcgg aaaaatatat ggtgtggcag gaaaaacggc tgaagcacgc tactatttga
     3241 gtcgaagcat ccaactgctg catcaatcag ctgatgaacg atcaaaaagt gaattttcgc
     3301 aaatttttta taattatgga aatttcttat tccatcaaaa tgaaatcgac gaagcgttag
     3361 aacaggtgaa tcaaggaatc tattgggctc aagagaagaa tagctactat tacctcaatg
     3421 atttatttgt gcttaaaagc ttaatataca agcgtaaaga agaaccagaa agagcagcat
     3481 tctatgaagg cttagcacaa gctgtgaaac aaatttcaaa aaatttgtaa atggtgtaga
     3541 ccattcttga cttcttctct aaataagagt actttagagg tagaaaaaca aagggagaga
     3601 atagaatgag aacttttatc tatgctgaca aattcttttt agcgtcaggt gtcaaacatg
     3661 caggctatct tgaaattacc gatggacttt ttggtgaata caccaaagaa ctacctgagg
     3721 gagaagtcaa catcattgac caaagcggca aatggattgc tcctggtttg gtagatacac
     3781 atattcacgg ctatatgaat catgatgtaa tggataatga tgcagaaggc atcaaagtga
     3841 tgtctgaagg tctgttatct tgtggagtga cttcattttt accaacaaca ttgacgtcaa
     3901 gcaaagaacg tttaaaagat gtagctgaga caatcggcaa aatgtatcag gaagcaccag
     3961 gagctaaaat caaaggaatc tattttgaag gtcctttctt cacagaagaa cacaaagggg
     4021 cacaaaaccc aagttatttc ggggatcctg atttggatac tttccatgaa tggcaagaag
     4081 cttcaggtgg tttaatcaaa aaaattgctt tagcaccgga acgtcaaggt gtagaagagt
     4141 ttgtcaaaca agtgactgaa gaaggagtag ttgtttctct aggacacagt aatgctacac
     4201 tagaagaagc gcaaaaagct gttgaagcag gcgcaagtgt atttgtccat gctttcaatg
     4261 gtatgcgtgg attgaatcat cgcgaaccag gtatggtggg tgcgttatta tctttagaac
     4321 atgtcttttc tgaattgatt tgtgatggcc atcatgtaca tccaaatgct gcgggaatcc
     4381 taatggaaaa agcaggacat gatcatgtcg cattaattac agactgtatg atggccggtg
     4441 ggatgcctga tggaaattac aatttaggcg aatttccagt agtagtaaaa gaaggaacag
     4501 cacgtctaga atctggcaac ttagctggaa gtatattgaa attgaaagaa gcaattaaaa
     4561 atgttgtaga ctggggatta gcaacaccag aacaagcagt catgatggct agtctgattc
     4621 cagcaatcag ctgtaaaatc gatgatacat gtggaaaaat cgctcaagga cgcgatgcag
     4681 actttatcgt attgaaccct gatatgacat tggaagcaac ttatctagat ggcgtggaac
     4741 gtttccacgc ataatataat ttaagttaac cttaaaacta aacttcttaa gtttggtttt
     4801 aaggtttttt ttgtgttcta gtaaaaatca ctttacataa gtttcaaaag tttctttaat
     4861 ttcctattgt tcaataagta acaatgtaaa gataaaatta aaaatgttaa tacgtattag
     4921 caaaataaaa gcttttttta ttgtgaataa atgaacataa ttaggaggag aaagatgaac
     4981 ttatttgaca tttttcgatc gactttgaca gatatgtcga ttgtcagtgc aatcacttca
     5041 acagttttta ttatattatt agggtttgtt tgtagaaaaa aggggatttt ttctgaatct
     5101 gttggaaaaa ttctatcgaa agtcgtctta acagtggctt tgccagcact ggcatttcga
     5161 gctttcatgc aagatatcaa tacagaatta ctgatgcaag gaatcaatgt cttgatttgg
     5221 ggattagtta tttatattat tcttattcta gtttcaaaac cttttttctt aagctataaa
     5281 ggggataagc aaacaacgtt gcgtgtcctg acgatctttg gttctacgac ctttttcgga
     5341 acgcctatcg tcagtgcgat ttatggtcct gtcggcgtga tgtattcctc aattttcaat
     5401 attggctacc gaatcttttt gtattcttat ggatacataa aaatgagtgg cttgaagatg
     5461 gaagctaaaa atatcaaagc gatgttcgtc aatccaatca ttatcgctac ttttgccggc
     5521 cttttcattt ggctgttcca agggtatctg ccacaagtgt cagttacagg tgcagaagga
     5581 gagataagcc aagtagcgtt tttgcgaatt gaccagactg caccgtggct atttcagccg
     5641 atggattatt tagctggttt aagttcacca ttggcgtggc tagcaatcgg cgcaacatta
     5701 ggtgaagtaa gcttcaaaaa agctgcatct gaaaaaactt catggtatta cagtctagtc
     5761 aaagtggtat ttgtacctgc attgaatatc gtgattctag cagttttgac ggcaacgaat
     5821 attctaccag tcaattttga agcactggca acaatcgtta tcatgatggc tacaccagct
     5881 gcaacagtgg cagcagccta tgctatcagt tttgataggg aggcactttt agcctccaat
     5941 gcatccttac tgtcaactat ttttgctgtg gtactgacac ctgtatggat cgttgtatta
     6001 caaatgattc atggcatagg tttattttca taagaaatgg aggaagaaag tatgagaatc
     6061 gcatgttacg gtgttcgtcc gaacgagata gatttttttg aaaaattgaa tatttaccat
     6121 tatgatctca gtctttatga agaactgttg acacatgaca atatcgtgtc agcaaaggac
     6181 catgatgctg tattgttgag gggaaattgt atagcagatg agaccaatct tgcaaaaatg
     6241 caggaatatg ggattcgtta tgtttttaca cggactgtgg gagtcaatca tatcgatcta
     6301 caagcggcag ctgattttgg tatgacagta gcccgtgtac catcgtattc gccaaatgcg
     6361 atagcagagt tatctttgac ttttgccatg atgcttttga gaaatactgc gtatacgacg
     6421 atccgaacat ctttcaaaga ttttcgagtg gatgagcaaa tgtttagtcg tgaaatcaga
     6481 aattgcacag tagggatcat aggaacaggc aggatagggt tgacggaagc tgttttgttt
     6541 aagggactag gagccaaagt gatcggctac gatattcatc agacagaagc tgctaaaaaa
     6601 gtattgacgt tccactcgct tgaagagtta ttagccaaaa gcgatattgt cagtattcat
     6661 gtacctcata tcccaggtga aaacgatcaa atgatcaatg aaggattttt agctcaaatg
     6721 aaaaaaggta gcatcttgat taatacagcc cgtggagagc ttcaagataa tgaagctatt
     6781 ttaagagctt tgaaaagcaa tcatttagct ggttttgcaa ccgatgtttt tgcaaatgaa
     6841 acagaggttt ttttccgatc cttcaagcca tgggagacga ttccagaccc tgctatccag
     6901 caattagtag aaatgtaccc tagagttctt gtaaccccgc atgtaggttc aaatacagat
     6961 gaggcattat caaatatgat ttcgacaagt ttcgagaact ttcgtgaaat aatagaaact
     7021 ggaaaaacga aaaatgaggt atctcttcct aaagcccgtc aattaagata agaaaacatg
     7081 gatattcgtc aataaaatgt ttaaaaatag tccaagtaaa cagttgttac ttctgtatac
     7141 ttggactatt ttgtatggga taattcgatg actcaacagt aatctgtgag ctttttccgc
     7201 ccattctttg tcaattcata acaggttagc ggccggccga tttccaaata tttgattctt
     7261 tcgttcaata tatcttgttc tactaaaaaa ttcaaatatt tcttgacgga tatacgtgac
     7321 agtgagcttt tttgagccag ttcttttgtt gaaaaaatag tatcttcttt tagaataaat
     7381 gcacttattt tttttaaagt cagttttgac agacctttag gcaaatcgat gaatgatggt
     7441 atttcgtgaa tgggagtggt gtggttgaat acttgatcga tcaatttctg atcggctttt
     7501 tcagtcgttt ggattgtctg agagaaagca agatactttt cgatcgccag ctgaaaacgt
     7561 tgcaaagtga acggtttgat caaataatct aaggcaccgt agcggatcac attctttatg
     7621 gtttcgatat catctgcagc agtgatcaaa atcactggga tatcatttcc ttgctgtcta
     7681 agccaagata aaaaatggat accactttcg ccaggcatgt atacatcaag cagcagcaga
     7741 tctgcgtttt tttgtctgaa atattttttt ccttcttcta catttctgaa actttcgatt
     7801 acgttcatat tagggatgct ttccacaaaa gtacgattca attctgcaac cattggatca
     7861 tcttcgatta tcaggacatt tgtcatcatt ttgatcttcc ttttttggta attctagata
     7921 gacgattgta ccgccatttg tttgtttgga aaattctaaa aatccaccgt ggcgtttgac
     7981 gattgaatgg atgagattca atccaaaccc acgattgatt cccttcgtcg aaaaacctag
     8041 cgtaaatatt ttttctgaga tttcttctga tatcccgaca ccgtcatcgc agacggtcac
     8101 gatgaatact tcagcttctg tgtcatagtt taaatgaatc cggacctgtc cgtttctttc
     8161 atgtttttgt agcacggctt cttttgcatt atcaagtaag ttccctaaca cttgcaaaag
     8221 tgaatggatg gagtcatcca tctccatttt agggataaaa gaatcgcttt ctaacagcat
     8281 ttcaacagat tgttctttgg cttcgtttat tttgcctaat aaaaaaccgg caattgcagg
     8341 tactttgatc agacttgaga cttggccaat ctctttttta taattttgat ttagctgctg
     8401 gataaaatgg gtgacttctt catacttctt caaatcaatc aaaccagaaa tgacatgaag
     8461 tttattcatg aattcatggg tttgagctct catggagttt atatattgtt tcgtcccccc
     8521 aagctcctcc attaatttca ttacttctga tcgatttcgt aaagttgcga ctgctcctaa
     8581 aaaacggtca ttgctaaaaa gaggtgtaac gctagaaata gtttctatcc catttaaata
     8641 catggattga gtccgaacgg tcgtttgatg ctcaatcgtc tctttaaaca aaacgtcata
     8701 tagattatca ctgatttttt tcctacttcg aaatccaata gctgctctgt ttggtagaaa
     8761 atgttttttg caggtgtatt gatcaagagg atagttttat cagaagagat ggctaagatt
     8821 ccttcatcta cttcattttc gataatcgtt ttttcactta actgttctgc tatttcttgt
     8881 ggttcaagtc caagcagtac ttttttcatt ttttgggcaa gaaaaacggc gcctatgatg
     8941 cctacgctaa gtccaataat caatgaaaaa acaatcattt tttgtccatc tttgacttga
     9001 ttgtcaatcg tgttgtttgt taagccaaca caaactgcac caataatctc ttgatcataa
     9061 taaataggga cgaaatagcg gaagccgaac cctaacattc cttctttttc agagaaaaat
     9121 tcttgtcctc caatcacttt tttcacatct tcatgacttg agaaaggaag accgatgtaa
     9181 cttgggtctg cgtgagaata tcgaatgcct tcagggtcca tgacaacgat aaaatctaaa
     9241 ttcgatgcaa tcatgatttc atttgttatt ccttgaatcg catgtgtcgg gtcaccagtc
     9301 tgcagctttt tttggatgag tttatcattg gcaacgattt tagcaatgct agagatttta
     9361 tctgacacac tagatcggtt catcgaaaga ataaaattcc tgatcaatat ggcagaaaca
     9421 atcaaagaaa cgaatgtgga gaaacaaacg acaaggatga tcgtgttctg gagctttaat
     9481 ggttttttct taaaaaaagg aaacataggc tacctcgaaa gaatttattg tgaaaatttt
     9541 aacatgaaaa caaaaattta acaaattgtc aacgataaac acaaccttcc tataaaaaac
     9601 accactgagt cggtaaaaga agctatacag aattttcaaa cattggtatg atagacgtag
     9661 aaatggaagg aggcgtgtat atgatagggg gaatcgcact tgagacgatt tattggtata
     9721 cattgctgat ttgtgcagga ttggcagtcc tattgattat ttttggagat gtattcgatt
     9781 ttgatggccc gcttgatccg atgcttatta tcccttggtt aactttcaca agcttatttg
     9841 gttttctagg tgagcgttta acagatcaat catctttatt tttatttatt gctagtggag
     9901 gcatatcgat agtgttggta tttttgctta atttctatat attgatgccg atgaaacatg
     9961 ccgaatcaac gatgtcgtct tctgaaaaaa ctctggaagg acaagtagct gttgtgatca
    10021 caccgatccc tgtacgaggt atgggagaaa ttcagttgaa aagtgttacc ggttccatta
    10081 gtcgtccagc ttgtttttac agcccccaag aacagacagc tgagcgggga acgaaagtat
    10141 tgatcattga gatcaaggaa agaatctgtt atgtcatgcc ttatgaaagc atgataaaag
    10201 cttaaaggag cgtgtgttaa atggaaatac cagttgtttt tatcgcgatc gcaatcgcag
    10261 ctttgatttt actgatgttg ctgatcgtct ttgtagcgaa gtaccagaca gcaaaaccgg
    10321 atgaagcgtt gatcatcagt ggaagttatt taggaagcaa aaatgtgcac attgatgaaa
    10381 gcaataacaa aatcaaaatt gtgcgtggag gtggcgcatt cgtcttgcca gtttttcaac
    10441 gttcgaatcg gatcagtcta ttatcgagta aattggacgt ctccacccct gaagtgtata
    10501 cggaacaagg cgtaccggtg atgtgtgatg gtacttcgat catcaaaatc ggttcatctg
    10561 tagaagagat tgctacagca gcagaacagt ttttaggcaa gacaagagaa gaactggaaa
    10621 atgaagcaag agaagtatta gaaggacact tgcgctcgat tcttggttct atgactgtag
    10681 aagaaatcta tcaaaatcgc gataagttca gtcaaagcgt acaagaagtc gcttctgtag
    10741 accttgcaaa aatggggttg atcatcgttt ctttcactat caaagaggtc agagacaaaa
    10801 acggttatct tgactcttta gggaaaccaa gaatcgccca agtcaaaaga gatgcagata
    10861 tagcagaagc ggaagctcta aaagaaacgc gtatcaaaaa agctcaagca gaaaaagaat
    10921 cacaagcagc tgaattacag cgacaaacag agatcgcaga atcattaaaa gaaaaagaac
    10981 tgaaattagc aacctacaaa caagaacaag atgttgctaa agcaaaagca gaccaagcct
    11041 acaatttaga aagtgcccga gcacaacaac aagtaatcga acaggaaatg cagattaaaa
    11101 tcgtagaacg tcaaaaacaa atcgaactgg aagaaaaaga aatcacacgt cgtgaaaagc
    11161 aatatgattc ggaagtgaag aaaaaagcag atgccgatcg gtacgctaaa gaacaagaag
    11221 cacaagctca aaaagtcaaa gaagtgactg aagccgaagc agaacgattc cgtgtggaag
    11281 cactggcaga agcggaagcc aataagacac gtttagctgg acaagcagaa gccgaagcag
    11341 cactagcaaa aggaaaagca gaagccgaag caaaacaaaa gatcgccaat gccttcaagg
    11401 aatatggcga agcagctgtc ttgagtatgg ttatcgatat gctaccgcaa ttgatgcgcg
    11461 aagcagcaca gccgctagga aatatcgaaa aaatctctgt tgtcgataca ggaagcagtt
    11521 caggagaaac cagtggagcg aaccgagtga caaattatgc cacaaatttg ctttcttcta
    11581 ctcaagaaac actaaaagcg acaacaggac ttgacttgaa ggaaatcgta gagaatttgt
    11641 cgacacgtgg gactactagc caagtaaata tgtatgaagc gccaaaagag gcagaacaaa
    11701 actcgatgaa ggaagaataa agtagtacac ttcaccgttc aatcaaaaat ggaggaagac
    11761 tttttaaagt tcttctctcc atttttttat tttattgcaa aagaaaatta gtcctcgcta
    11821 tttttctttt gtttttggat cttagcttct atctcttgta aatttgttct tagcaatcgt
    11881 tctttctttt ggagttcgac caaatcttct gatagttctt ccttcttttc tgtttcagga
    11941 ggacgaagaa agaaattgat accgattgca atgaatgtcc ctataaaagt atctagtaca
    12001 cgttggatag catacaaagc ggattcgcct tgagggatgc tcaacgcaat cagcaacaac
    12061 gtagctattg cggaaatgat accggaatta ttgttaatac catctgacac gacgatcaca
    12121 ataataacta gaataggaag caagatcaat tctaccaaaa aatcattgtg aaaatagctt
    12181 ttgacaaaaa aataaatgat agctaatgta ccacctaatg tattgccgat gatcctagac
    12241 tttccaaaag aaacggttgt agtcaagtcc tgacgcaaag aaaaaacagc agataatgca
    12301 gcaatcatcg ggattcctcg ttgagtcaaa tgaaaaaaca agatacataa aaaaacagct
    12361 aaggcacttt tgatcgtacg catacctagt cgaaaacggc caaattgcat agagattctc
    12421 ctttttggtc tttttactat catacctaaa cttttgtctg atagctagtt tttcattatt
    12481 caagtataat taaaataaaa aagggggaag taaatgcgta taggaatgcg aacagtcaaa
    12541 acagtgatca gtgtcttctt ttcgatggtc acagcgggta gcttatcgct gttgtattgg
    12601 ccagctgcag ggatcattgc attattaagt gtaggaaata ccaagcgctc tacattgcgt
    12661 acgggcatga atcgaatcgc agcctttata ttagctacgg caacagcact gttcagtttt
    12721 tttgctgttg ggtatactat ttttggcttc agtctttttt tattcctgtt catcccgctt
    12781 gcctctcgct tcaaattaac cgaagggata gtagtaaatt cggttttggt cactcattat
    12841 ttagtggagg aaaacatgtc ttggcagctg atcggcaatg aagcgggatt aatggcgatt
    12901 ggattagtat ttgctttgct tgcaaatgtt tacatgccag atcgtacgaa gcagctgaag
    12961 gaaaaccaaa tacagatcga aaaagaattt cgaaatattt tgagacaaat ggcagaattt
    13021 cttttatcag aaaataaaga agatgtgcag atcaaatgcg aacatttact gacattcatt
    13081 cgcgaaagcc aagaagatgc cagagaacat caagaaaact actggctcag acagccgcta
    13141 tactacgaaa cttacttctc tatgagaaga gcacaggcca atgtgattaa agacatgctg
    13201 gaaaatctag agagaatcca gcaaccagct tattatggaa aacatatcta tggtttattg
    13261 atttatactg cagaaacatt ttcagagtca aatgatggca gacaaatttt aacacgtatt
    13321 gaagaagttt atgtattgta tcggcaaatg cctctgccga ctagtcgccc tgaattcgag
    13381 gatcgagcag aattgttcca gtttttgcag tcttttaaaa gttttattga aatcaaggca
    13441 gaattctccc aacaaaaaat ccaaaaatag aggttgtgaa ttcagctaat attcaggtca
    13501 aaaagctgat ttcacaacct cttctttaaa cggtgttctc ctgtcaactc ctcggtcaca
    13561 agtcacaata ttcaacaaac atgagaagct gttttttgaa attgctcctt gtgactcgga
    13621 gctgaacggt aggctcacaa cctctttctt aaacggtgtt caaaagcttt cctctgcggt
    13681 aataagtcca gccaaacgaa aaataggagg agctattttt gtttggctgt tcttattact
    13741 tgatgcagaa cagctttttc acaacctttt aaaattacat atttttccat agaacttgca
    13801 tttgatccaa gatttcgatg acatcttttg tcaagaagag agagcgattg ggcaagtcac
    13861 cttcaatcat gtgtaccata ttctttattt cgtaattcat tgcttcagat gtattcccgc
    13921 tttcgatgaa ttcctttgta ccatctgtaa ataagatctc cgcacgatca gcacgcgggt
    13981 aatcagcaat cgtcacataa ccgttctcaa aggcaacgat accgactttt ggcatttttg
    14041 cctgaaaagt caagctgaca gcagcaagtt cattttcttt gttacgcaag atagtgacgg
    14101 attgttcgtc cacgcctgtt tcaaaaggaa ccattgtaga ggcaactact tcaggttgag
    14161 agctcaaaaa gaaacgagcg aaagatacag catacgtacc gatatccaac agagctcctc
    14221 cagctaattc tggattgaag aaccggtttt tagggtctgg ttctttgtaa ctgccgaaag
    14281 gtgcttggat catttttaaa gcccccagtt ttcctgtatc cattattgag cgtaactgct
    14341 gataaagtgg catgttgaag attgtcatcg cttctgctaa gatcaaattc ttttcttctg
    14401 ctaagcgcat agcgtcagcc agttcttttt tattcatcgt gatggctttt tcacatagaa
    14461 cgtgtttgcc tgcttccaat gctgccaaga tatggtcgat atgctgtcta tttggtacag
    14521 caatgtacac gatgtcgatt tcagcatcgt ctaacatttc ttgatagctt ccgtaagctt
    14581 ttggaatatt gtaacggtga gcgaagtttt ccgctttttc tgaagttctg gaagcaactg
    14641 ctgttagttc gctcgtctct tgattgaagc tttcggcaaa ctcatgtgcg atggtaccaa
    14701 gaccaacgat tccccattga tattttttca tctgaaaacg ctccttcata gttggattga
    14761 gtttcttgtc tgtctattat tataacaaaa atcacgaaga ataaagagga gaggacttga
    14821 aacattaaaa aaaatgaaag cagcgattta agaggtgctt tttgatcaaa acttaagtag
    14881 aatagttaaa aggaggggat aaacgtgcat caagtatata ttgatcttat tatgagtgta
    14941 ttattagaac agtttgaaac tgaaaaaaat tttttagatg aatacttgct gatcagtcca
    15001 gaacaatggc aaaaatggaa agatggcgag aaaaatctgc catctgaagc gatgcagaaa
    15061 gtaaaaaatc ttttcactga ttatgaatgg atgctaacgc aaaagatttt gcgtcaaacg
    15121 attatttttc ccgaaaaacg aaacgttgcc gttgcagagt acaagcaaat caaaacacgc
    15181 atcgcgcaaa aatggcttag cagcaaagca gcaaaagtcg agctgatccc tttgaaaaat
    15241 aatcagcagg ctggtagata ccttgacttg aaagtaagta ttcaatatga tgaatggggc
    15301 tatgatgata ttttgaattt tcgtctgcca gcagatgttc aaaaacagat cgaaggagaa
    15361 aaaatcgaac ttctcgattg ggtgaatgaa aatctggaag aaacttacgt tcatgaggcg
    15421 aatggggaac gtgaagaaca acgaaaggat ttttcaagtg aataaatttt taggatttgg
    15481 agcagttgtg attatgatcg cagcaatggg ctatgttatt tttagcgatg atgattcgca
    15541 tgttcaagcc ggcaatcaag cagtcgaacg aacaagcacc aaaacaactg ctagtaaaga
    15601 aaagaacagt caaacaacca gcagcaaggt aaaggacaaa gaaacaaaag atcgtacgtc
    15661 caaacaattg ccagatgtta aaacagacga ttggaagcta gttttggttg gtccagatca
    15721 caaattagaa aaagaaattg atgagtctac tcaattggca tcattaagta acggatactt
    15781 gatcgacaaa cgcattgctc cagaatatga agcatttgcc aaggctgctg aagcagctgg
    15841 atttccatta gtgatggtct cagcttaccg gtctgtatca tcccaacaac aagttttcga
    15901 acaaaatgtc caagatgtga tgagtcgtca aggtgtatca gaagaggagg cgacaaagat
    15961 tactaaagaa acgattacgg agccaggata cagcgaacac cacacaggtc tggcagtcga
    16021 tgtcgtcgat caaaactggt acaacagtta tccttctact gtattggatg caagttacgg
    16081 agatcagcct ggagctaaat ggatcgcaga taatgctgcg cagtatggat ttatcgttcg
    16141 ttatccaaaa ggacacgaag atataactaa gatcacatat gaaccttggc acttacgtta
    16201 tgtcggtaaa gaaaacgctg agtatatcac caaacaccaa ttgacgctag aagaatatct
    16261 gaatgaatta aatgaaaagt aggaattgat catggcgaaa aaaaagtgga aaaagcaaaa
    16321 gcgcaagaat atccgttggc cagcagtggt tgccggtgta gcagtgatac tcttagcctt
    16381 tgttttttcc ttgaagaatc tgtcttctcc ttttactgat aatcagcaag aaaatgaagc
    16441 gcaatcccat cagcaattta ttgaacggct tgttccgcat gcccaagaac tacaagatgg
    16501 ttatggagtg cttcctagta tcattttagg acaagctata ttagaatcaa attggggaaa
    16561 aagtaccttg gctagcaaat acaataatct tttcgggatc aaggcttatg gggatcagaa
    16621 gaaagtaagc ctggaaacaa aggaatttgt taacgaagaa tggataacta tccaaggaga
    16681 cttcaaagtg tatgattcat gggaacagtc catggatgac catacacaac tgttcgtcca
    16741 aggagtagat tggaatcctg cgctgtatga aaaagtgatt acggccacca actatcagga
    16801 agccgcacaa gcattgcaag atgcaggtta tgcgacagac cccggttatg cgcaaaaaat
    16861 catccaggtc atcgagacgt atcaattgaa tcagtatgac cggagatagc aaaggagaag
    16921 tggctgatgg cagaacaatt tacgccagaa atcatgacgg aattgagaaa agatatcgta
    16981 agagtaccgg aaatcatttt agaagcaagc gggatcaaga tatttggaaa attgatccgt
    17041 tcgatcatct ttactacgga tattgcgatc atacgtaata caaatgcgaa tgcagtaatt
    17101 gctgtgtatc cttttacacc tcatccagcg attactaaaa gcattattga ggcagctgac
    17161 attccagttt tctccggtgt aggtggtggt ttgacacaag gtgctcgttc ttcctacatg
    17221 agcatgttcg cagaagcgca aggttcgtta ggggtcgttt tgaacggtcc tacgccttta
    17281 gagacagtaa aagaagtttg tcgagtagtt gatattccag ttatcagtac ggtaacgtcg
    17341 aaatatacag aaatagatga aaagttagca gctggtattt cgattatcaa tatcagtgca
    17401 ggtaaagaaa ctgcagaagc agtacgccat tttcgtaaaa aatatcctga acttcctatc
    17461 attgcgacag gtggtccaac ggaagaaagt attgctgaga ccattcaagc aggagcaaat
    17521 gccatcacat atacgccacc aagtagcgga gagcttttta gtcgtaaaat ggaaaaatat
    17581 cgggaaactg agaaaaagaa tcatgaataa caggtgagaa tcaaaagacg aggaagagca
    17641 gatagtggct cttcctcgtc ttttgtactc cagtactatt tgttcagaat tcaaaaaaaa
    17701 gagaaatttt tttgtttttt tacctgtaat gtacataaga agagttaaaa ccttttgtta
    17761 ttattagcat tctaacaaaa aaatgtcttg atttattgaa gcgctttcta tagaatgaaa
    17821 aacgaataaa aactaaaaaa ggcacccgac aatttagtag cagctaaatt gtcggggctt
    17881 gaaaagtcag cgggaactga ccaatcaagt tgccatagtc aatgcttgtg catcgacgtg
    17941 tatattgtac ctaatttcat acagaattac tagttatttt tctgtttttt agggaagagc
    18001 gcacacgaag aagcatgctt atttagctat gtcaaggata ttgggcagtt gtctgatatc
    18061 cttttttctt tgcgtaatta tcctcccatc attgaagcaa gaagtgtttt tagcgatgaa
    18121 agaagaatca gcactatcta atttttcttg aaagtattga gttgttcatc ctaggcagaa
    18181 cgataaggca agtcttggtt tttattcccc ttgaaaaaga tcgtttaata aatatgttct
    18241 gtataaaaat acagtatatt gaaaaataac aatggaagta gaggtgcaga gaatgaagaa
    18301 aagaatgaga atcatcttag ctttaagtgt tatgttattc ttcttgacgg cttgtgggca
    18361 agaagatgac aaaaaaatca cgctgaacat ggcttggtgg ggttcgcaag tccgacacga
    18421 tgcaacagta aaagtaatcg agctttatga agaaaaaaat ccccatgtga cgatcgatta
    18481 tgaattttat gattatgaag gatattacac aaaattaggt acactagcag catcagatga
    18541 tatctgggac attttccaac tgaacaatca atttcctcaa tacatcaatc agattgaacc
    18601 attagatgaa tatgtggagc aagggataat tgatatttct aatgcagatg aatcctattt
    18661 agcaacgacg acttacgacg ggcaattagt tggactgtct aacggggtga attcgtttgc
    18721 gattgcttac aataaaaata tatttgaaca attaaatatc cctgaaccag cttcaaattg
    18781 gacatgggat gaatttgaac aaatcagcta tcaaatcact gaagaattag gaatctatgc
    18841 tatttcaaga ttcgaagatt ttatagctgg ctgtattatt caaataccac aagttgagaa
    18901 aggattgaat ttttataatc gggaagatct atctaacagc ttgggatttg aaaatccaga
    18961 ctatctaaca gattttttcc agctgcgtaa aaatctggta gacaaagggg cccatccaga
    19021 accaggtggt ggagctgcaa gtacgacgga tctgtctttt caggcggtta gggatagaga
    19081 agcggcaatg gtgtttctat caagtaacca gttgacagaa atattgtcag gggctcctga
    19141 agatatggag attcagttga ttaatccacc tcgcagaaaa gcagatggag aatctggtat
    19201 ccctttacgt tcttcgcaaa tgctgagtat ggcaaaaagc tcagcccata aagaagaagc
    19261 tgctaagttt attgatttct ttcaaaacag tgaagaagcc aatgaaattt taaaaggaga
    19321 acgtggtgta ccaatcatgt cgaatattcg agaacagctc gctcgtgcag atgatgcaac
    19381 tttgcaagcg acatttgatt atttagaaat gatttccgat atggacaacg gcgaagtgaa
    19441 tgtctttgat agtgctttga atccggaaat tcaagaccaa tacaatcttt tagttgaaaa
    19501 agtcatttat gaagaagtaa cagcagaaga agcagcagag agtctttatg agtttgcgtc
    19561 aaacattcta ggatagcagc aggaggaagg catgaaaaaa gaaaaactaa aacggttctt
    19621 ggatcaagac aatgtggtcg gttacgtatt tgcttctcca ttcatcctag gatttctatt
    19681 gataacagtg ataccgatga tcttgtcact ttattattcg ttcaccgatt atcgtttggg
    19741 aaatccagtc tcatggatcg gcttggataa ttatataaag atgctgagtg atgcccgttt
    19801 tttgaactcc atccgagtca cttttctcta tgtatttgca tctgtacctg tgaaactgat
    19861 ctttggtcta ttgattgctt atcttttaac gaggaatatc aaaggaacga ctttctttcg
    19921 ttctttgtat tatgtgccta gtttgatcgg tggcagtatt tctatcgctc tagtttggcg
    19981 ggagttgttt tctaaaaacg ggttagtgaa tattttcctg gaacgattag gcgcacctgc
    20041 gctttcctgg tttagcgatc aaaaactggt catgatccct cttgttttga tgtctgcttg
    20101 gcaattcggt tcggcaatga tcatctttgc tgcaggtatc aaagagatcc caggctcgta
    20161 ttatgaagcg gcagagatcg atggagcgaa caaatggcag acgttttaca agatcacgtt
    20221 acctcttctt tcgccgatca ttttgtataa cttggttatg cagacaatcg cggcgtttat
    20281 gacttttacg caggcattta tcattaccca aggtggtccg aatgatgcca cgaactttta
    20341 tgctctttat gtgtataacc aagctttttc ttttaattct atggggtatg ctagtgctat
    20401 ttcgtggatc atgctgttga ttatgggagc tgtcaccttt ctgattttca aatcatcaaa
    20461 aaaatgggtc gttgtgtgaa tgagaggagg aagaaatgaa taatacagta acgaaatggt
    20521 ttcaatacgg ttttattttg ctattaggtc tagtcatgat ttatccggtc ttatggatga
    20581 tcgcaggttc ttttaaaacg gatcaagaga ttatgagtgg ttcgctgaat ttgattccag
    20641 agacttttca atgggaaaat tacgcaaaag gatgggcggg gtttgctgga atttcatttt
    20701 ttactttctt taggaattcg tttgtcatct ctgcagtttc gacgataggg acagttctga
    20761 gctcgacttg tattgcttac gcattatcga gaatcgattt caaaggaaaa agattctggt
    20821 tcgtcgtcat gttagtaacg atgatgattc ctgcacaagt gattttgatt ccgcagttta
    20881 ttatttacaa tcggctgaat ttggttggga cgtatgtgcc gctgatttta ccacattttt
    20941 ttggacaagc atttttcatt taccagatca tgcaattcat ggtcagcatc cccaaagagt
    21001 tagatgaatc agcgattatt gacggatgca gcaagtatag tgtctttacc aaaattattt
    21061 ttcctttgct gaaaccttcg atcatcacga cgatcatcat ccagttttat tggaaatggg
    21121 acgacttcat gggaccattg atttatttaa acaagccgag atcttacacg gtatcgattg
    21181 ccatcaaatt atttgcagac gctggatcta gtacgactta cgcgagtatg tttgcgatgt
    21241 ctacgttgtc gctgctaccg gtttttctga ttttcttatt cttcaataaa tatcttgtcc
    21301 aggggatcag tacaagcggt ctgaagggct gaatatgaaa aagccaatag aagagatgtt
    21361 tctttacaag ctcaactact atgtctgtcg gattttttta accagtctta tcagtaatgc
    21421 tcttttcgct ttagttctag gatgtttgtt cactttagga ttagtgctgt ctgctcgtgt
    21481 tgtctatctg atttattttt tgatgatgta tccttcttat tatctatctg tccattactt
    21541 ggcagaaaaa aaggtatgtt ggaggaaagg aaaaatcaaa cggatgtgtt tcatcattac
    21601 gttgtttcag ctgtttgtca ttatttttgc agttgattgg tatttattag tgggaaagat
    21661 tggagcttgg tatctgattc cttttctatt gtgtctgttg ctttttgtat cccatagttt
    21721 ttttagtacg ctaattgata tctgcaaaga agataaagca gatagtcttg tttatttgat
    21781 caaaaggaat atctggctgt tgtcaaaaaa cgtcaagggg tttctgtggt atttatgcct
    21841 tttgtatgga ctgttctggt gtatacagca tgatttttta ctcactgcat tactgtatcc
    21901 agggctgcca tttgtcacag tattttgctt aaaagaaaag gagaatgact ttaaatgaag
    21961 aaaaaatatg tacaagtcgg acttggtggg agagcgcgtt ttttttatga ggcaattgcc
    22021 tctacgtatc atcaaacttg tgaactagtc ggtttttgtg atgtatctca aacaaggatg
    22081 gattatgcaa atcggatact tgtgaacaag tatggacaga aaaaagtaaa gacatgtatg
    22141 ccatcacaat ttgagcaact actggatgac gtacggccgg ctgaagtcat tattacgtca
    22201 gtagatcgaa cgcatcatga ttatatcatt cgtgcaatga aaaaaggata tgatgttatt
    22261 tgcgaaaaac ctctgactat cgatgaggaa aaagctcaag aaataataac ggtccaaaaa
    22321 cagacgggaa gaagcctgcg agtcactttt aattatcgtt atgcaccgta tcacacgaag
    22381 ataaaggaac tgatagaaag tgatgtgatt ggtgatgtgt tttctatcca cttcgaatgg
    22441 ctgttaaata cgcaacacgg ggcagattat ttcagaagat ggcatcgaaa taagcacaat
    22501 agcggcgggc ttcttgttca taaatctacc catcattttg atctagtgaa tttttggttg
    22561 aacagccgtc cccaaaaggt atttgcattc ggtggattaa acttttatgg gatgcataat
    22621 gcggagaaac gcggagtaga aatattttac agtcgatgct atggaagcga actagctaaa
    22681 gctgatccat ttgctataga cctgtcagcc aatgaggaat tgcgagaaat gtatttagaa
    22741 gcagaaaaag acagtggata tattcgtgac cgcagtgtat tttccgatga tatctctatt
    22801 gaagatacac taggcgtaac ggtcaaatat gaaactggtg cgattttgac gtattcgcta
    22861 aacgcgtata tgccgtggga aggattcaat gtttctttca atggcagcaa aggacggatc
    22921 gaaatgaaag tgatcgaaaa gtcttacatc aatgcaggtg gagataaaaa ggatgaagga
    22981 gcagccgttc ttcagtccat ccatgtctat ccgatgttcg gtgagccata tgaggtaatc
    23041 gtcgaacaag aagcgggcgg acatggcgga ggagatccgc gtttattaga tgatctattt
    23101 ggtgaagaaa aagaagaaga tccgtggaat cgggcagcaa ctcacgtaga tggtattttg
    23161 tcgattttga caggaatcgc agcaaatcat tctattgctt caggaaaagc agtagtgatt
    23221 gacgagcttg tcagcttaaa agaataagaa tagatttacg gaaattactt cccgtagttt
    23281 ataaaatctt gccttattgc cgataggctg tcttttgaac actatttatt cggaaaaagg
    23341 ggctatgaca tgctttttgt catgccttct ttttatgtgg gctgcttttt tagataggag
    23401 aaaataaaaa taactattta aacccgaaca aaaaggaata atgcattaaa aatcattaga
    23461 ttttacaaaa aaataagtaa accacgttgt cagtttcaga aagtagtgtt agactgtttt
    23521 caatatttga aacaacattt tttattcaaa tatggcaaac tgccttcacg tgcaaaacag
    23581 ttgcaagaaa atgaatttac actattatta gttttacata cctacttata tatcgtcata
    23641 atatggatga cagtttctag ccagtaccgt aaatgctgga ctataagtaa aagattggct
    23701 atttcaccct tcttttctta tgataaagtg gagggtgttt ttctttaaca gaaacatagt
    23761 aggtttttgc acaaaagcgg ttatttcggt attaataaat gataaaggag caaataaagt
    23821 gaaagaatta gttgaacgta ttcaaaaaga cggacgtata ttaggcgagg gcgtattaaa
    23881 agtcgacagc ttcgtcactc accaagtaga ccctgtattg atggaacaaa tgggaaaacg
    23941 gtttgcagaa gtatttaaag aacaaggaat cacgaaagtt gtgaccattg aagcttctgg
    24001 gatcgcacca gctttatttg ctgcaagaga attagatgtt ccaatgatct tcgctagaaa
    24061 agcaaaaagt ttgacgatgg atgaagaatt attgacagct tctgtttatt cttttacgaa
    24121 acaagtgaca agtacgattt ctatttctcg taaattttta tcttcagaag acaaagtatt
    24181 gattatcgac gatttcttgg caaacggaca agcggcaaaa ggattgatcg aattatgcca
    24241 gcaagctgga gcgcaagtag aaggaatcgg gatcgtcatc gaaaagtctt tccaagatgg
    24301 acgtcagtta cttgaagaaa tgggattgag agtcgtttct cttgcgcgta ttgcttcctt
    24361 gacgaatgga caagttgagt ttcttgagga ggacgcataa tcgtggaaaa agaaacacaa
    24421 aatggaaaag ctgcggtttt agggctgcag catctgctag cgatgtatgc aggagcagta
    24481 gcggtgcctc ttttgatcgg tacaggacta ggctttaatc aagaacagat gacttatttg
    24541 atttcaattg atatctttat gtgtggatta gcgacattat tgcaattgac agttaaccga
    24601 tttttcggaa ttggcttgcc tgtcgtttta ggatgtgcga tccaagcagt agctccactg
    24661 atcttgatcg gaaccaatga aggagtagga gctatctacg gatctattat cgcttctggg
    24721 atctttgttg tgttagtttc tggtgtcttt tctaaaatta aaaaactatt ccctcctata
    24781 gtaacaggaa cggttatcac cgttattggt ttgactttga ttcctgtagc aatcgagaaa
    24841 atgggtggag gtaatgcaac agcagctgat tttggtgaca aaacaaatct gctacttgca
    24901 tttgtgacga ttctcctaat tgtaggcgtg caaatgctgg caaaagggtt cattcgttca
    24961 atcgcggtat tgattggttt agtcggagga agcatcttag ctgctttcat gggaatgatt
    25021 gatctgagcg cgattggaga tgcgccgttg ttccatgttc cacaaccctt ttattttggt
    25081 aaaccaactt tcgacgtatg gtcgatttta ctaatgatca tcatttccat ggtcagcatg
    25141 gtagaatcaa caggtgtata ttttgcactt ggtgacatta ctgggaaaaa tgttggagaa
    25201 gaagaattga aaaagggata tcgtgcagaa ggacttgccg ttatcttagg cggtattttc
    25261 aatacattcc cttatactgg cttttctcaa aatgtcggat tggttcaact ttcgggaatc
    25321 aaaacaagaa aacccatcta tttctctgca ttcttcttga ttgttttagg attattccct
    25381 aaaatcggtg cgttagcaca aatcatccct gagccggtac ttggtggagg aatgttagtc
    25441 atgttcggga tggtggcagt ccaaggaatc cgtatgctgt tggaagttga tttcagcaat
    25501 gataaaaatc tattgattgt tgctgtttct gttggatttg ggctgggttt caatgttacg
    25561 ccgacattat tcagtcaaat gccgcaaaca ttgcaaatgt tcactggaaa tggcatcgta
    25621 atgagtagca ttacggctat catattgaat ttgatcttta atggattgaa aaaagatgaa
    25681 gaaatattgg aagaagcctt caagaagtaa tagagcaaaa gaaaggttgt gaaatcagcg
    25741 ttttgacctg attgttagag aaacaaacgg aaaaatagtt cctcgtattt tgccgtttgt
    25801 ttgagctaat accgagggtc agctgattga acaccgttga aggaagaggt cgtgagcctg
    25861 ccgttcatct ccgagtcaca aggaacaatt tcaaaaaaaa gcttctcatg tttgttgaat
    25921 attgttcctt gtgaccgagg agttggcagg agaacaccgt ttatccataa aaaggaatgt
    25981 gacctaactt ttgtcacatt cctttttttt atctttaata aacacgaaca ataaaatgtt
    26041 tttctttgtt aacattcgaa atttctttga catcaaaaaa agtgattgtt aaaatatgaa
    26101 tgtagaaaaa ctgggaggaa aaacaatgac agcaaaaatc tctgtgatta tggggagtac
    26161 ttcagattgg gaaacaatga aagaagcatg tcaaatattg gatgaattcg gtgtgtctta
    26221 tgaaaaaaag gtcgtttctg ctcatcgaac cccagatttg atgtttgaat atgcacaaaa
    26281 cgctcgaaaa aaaggaatca aaatcattat tgcaggagca gggggagccg cgcatctgcc
    26341 gggtatggtc gcatcaaaaa caactttgcc ggttatcggt gtaccggtcc aatcacgaac
    26401 attaaatggt ttggattcgc ttctttcgat tgtccaaatg cctggaggag tacctgtagc
    26461 tactacagca atcggaaaag cgggagcaat taatgctgga ctacttgcga tacagatgct
    26521 ttccatgtat gatttagaat tggaggctaa attggctgaa agacgttcaa tgttggctaa
    26581 aactgttata gaaagtagtg atcaacttgg ttaaaccttt gttgcctggt tcaacgatcg
    26641 ggatcgtcgg tggcggtcaa ttaggtcgta tgatggcgat tagtgcaaaa gaaatgggct
    26701 ttaaagtagg tgtgctggat cctgtgagcg attgtccagc cgcacaagtt gcagattggc
    26761 atattgaaag tgtctatgat gacacctttg cgctgaaaga gcttgccaga agaacagatg
    26821 tcattaccta tgaattcgaa aacgtcagtg tagaggcgtt aaatgcgatt ttacccatgt
    26881 catttattcc tcaagggaca gacttgcttg cgattacgca agaccgcctg ttagaaaaat
    26941 cttttttgga aacgaataac atcgtgattg ctccttatgc aacgatcgtc agtccgacgg
    27001 atatccaaga tgcgattgac gggatcggct atccttgtgt tttgaaaacc actcgaggcg
    27061 gctatgatgg caaggggcag tatgttttga aaagtcgggc ggatctagct cctgccatgg
    27121 accttttaag agaaggaacc tgtgttttag aagcatggat cccgtttgaa aaagagattt
    27181 cgatcatggt ggcaggaaat ggtcaaggag atttcacgac ttttccggtc gtggaaaaca
    27241 tccaccacaa caatattctt catgaaacga ttgctccagc cgcgattgat caggatgtga
    27301 tcgaggaggc tgagcgtatt gcccgtgtga ttgcagaagc agtgagcctt tcaggtgttt
    27361 taggggtaga aatgttttta acaaaaacag gcgggctata tgtgaatgaa ttagctcctc
    27421 gtcctcacaa ttctggacat tattctattg aagcttgttc tatgagtcag ttcgatgccc
    27481 atattcgagg tatttgtggt tggccattag gagaaaaagt acgtttgata agcaatgcag
    27541 taatggtcaa tgttttggga gaacaactgc tggaaagcta tcgcttgatt gagaataagc
    27601 cagactggca attccatttc tatggaaaaa aacaagcaaa aaaaggtcgc aagatgggac
    27661 atatcactat cttgacagaa gacatccagc aaacgctgga agaaatcaaa caaacgaata
    27721 tttgggatta gaggagaaaa aacatgttag aacgttatac acgccctgaa atggggaata
    27781 tctggacgga agagaacaaa taccgtgcgt ggctcgaagt cgagatttta gcagatgaag
    27841 cttgggcaga acttggtgaa atcccgcaag aagatgtgaa aaaaattcgt gagcatgcat
    27901 catttgatat cgatcggatc ttggaaatcg aaaaattaac acgccatgat gtcgttgcgt
    27961 ttacacgagc ggtttctgaa acattgggag aagaaagaaa atgggtccat tatggtctaa
    28021 caagtacgga tgtcgtagat actgcttatg gctatctcat caagcaagca aatgatattt
    28081 tacgggaaga cttgaaacgt tttacggaaa tcattggcga aaaagcaaaa gaacacaaat
    28141 atacagtgat gatgggtcgg acacacggtg tccatgctga accaactact tttggattga
    28201 aacttgccac atggtattca gaaatgaaac ggaacatcga acgatttgaa catgcggcaa
    28261 aaggagtaga agcaggaaaa atctcaggag cagtgggaac gttcgcaaat atcccgccat
    28321 ttattgaaga gtatgtatgt aaacaattgg ggatccgtcc acaagaaatt tctactcaag
    28381 ttctccctcg ggatctacat gctgaatatt tctcagcgat ggcgcttatt gctacaagta
    28441 ttgaacgttt tgcaacagag atacgcggat tgcaaaaatc cgaaacacgt gaagtagaag
    28501 aattttttgc gaaaggtcaa aaaggttctt ctgctatgcc gcacaaaagg aatccgatcg
    28561 gttcagaaaa tatggctggt ctagccagag tggtgcgcgg acacatggtc actgcctatg
    28621 aaaatgtcac attatggcat gaaagagata tttctcattc ttcagcagaa cgaatcatct
    28681 tgcctgatac cacgatttta ttgaattaca tgttaaatcg ttttggcaat atcgttaaaa
    28741 atctaacggt ctttcctgaa aacatgaagc ggaatatgtc tgcaacattt ggtttgattt
    28801 atagccagcg cgttatgctg aaattgatcg ataagggaat gacaagagaa gaagcttatg
    28861 atcttgttca gccaaaaact gcgtacgctt gggacaacca agtgcagttc cgcccgctgt
    28921 tagaagaaga tccaaccatc acatcggtat tatctaaaga agaaatagac gatgcctttg
    28981 attatcatca tcatttgaaa aacgttgacg tgatattcaa acgagtaggt ttggaataaa
    29041 gaagagtgag ttgcaaaatt caattaaaat agaatagcaa aaataaccaa aaaagaagca
    29101 gatccgttag cggttctgct tcttttagtt tattatattt tcttatcaat aataggaacc
    29161 tgattttaaa agcggctacc tctttaccgt gcctctttac atacaaaaaa tagaggaatt
    29221 aagcgtaaat ggcttggcta ttataactaa aatgctggtt atggagatgt tgcagcaagt
    29281 tttcgagaaa agcgtattcc atctcttgtc cattgaataa gatctggata cgataatgat
    29341 ttttgaaacg cttctgttca tgaatctgac tgattgaaag ttcgcctttg tgttctgtct
    29401 gataaagaaa agtcctttta cggcattcag cacagcgctt ggttgctcgg cggatttttc
    29461 ggaatgtata aaaactagta tctttattgc ataaataaac gtctttgatc gacagcaaat
    29521 cattatatag acaggaacgt tcttcagctg ttaattctga taaaaaaagc tgaccttgtt
    29581 ttattgcatc ttccatcggc aagtgcctcc tcgaacccat tatccaaatt tttagttaat
    29641 tctaatatac catcattaag tataaatgta aacgcttgtt gatggtataa gattttcgtt
    29701 tctgataaaa cacgaacatt aaaagaatct aatgccttaa atgtacatat ttttgttgat
    29761 ttataaaaag atgattgcta aaatttaaag tgaaaaaacg aacaaaaaac gatgtatttg
    29821 cttttaatgt aaataaaaag gagagacgta catggagaag aaagaacttt tgtatgaagg
    29881 aaaagccaaa aaaatatatc ttacttctga tgagaacttg atttggatag aatatttaga
    29941 tcaagcaact gcgttgaatg gcgcgaggaa agaccagata agtggaaaag gagaattgaa
    30001 taatcaaatc acaagtgcaa ttttccgtta tctgactcaa agaggaataa aaaatcattt
    30061 tattgaacaa ttgtctaaaa ccgaacaatt agcaaaaaaa gtacaaatta tccctctgga
    30121 agtggttatc cgaaatattg cagcaggaag tttctcaaaa cgtctaggtg ttcccgaagg
    30181 taaagaattc atcaaaccaa tcattgaatt ctactataag gatgaccagt tggatgatcc
    30241 atttatcaat gaagagcata tctatttctt acaacttgca aagccggaag aaatcagtga
    30301 gctgaaagcc caagcgttgg ctattaatga aattttgacc gaattatttg ctaaggtcgg
    30361 tttggtttta gtagatttca agctagaatt tggccggtcg aatggacaaa ttttgcttgc
    30421 ggatgaagta acaccggata cttgccgatt atgggatgaa cgtacgaatg aacatatgga
    30481 caaagacgtt taccgcagag atctaggtga tttgatccca gtctatcaag aagtatataa
    30541 ccgtctatcg gaactaactg aagaaaagga gcgagtatga tgtatttcgt aaaagtatat
    30601 gtaacctata aagattcagt gttagatcct caaggggagg cagtaaaaaa agcagtccat
    30661 cgtatgggat atgaaacaat cgaagatatc cgaataggaa aatactttga gatacaactt
    30721 gctgatgcag aagaaccaat cgatacagtg attgaaacga tttgtgacaa gctgcttgca
    30781 aatgtaaata tggaaacata ccgatatgaa atcaaaaaaa tggaggaagt ataacatgaa
    30841 atttgcggtc atcgtttttc caggttcaaa ttgtgacgca gatatgttat gggcagttcg
    30901 cgagatcatg ggcgctgatg ccgaatttgt acggcatgat gagtcctctt tagaaggatt
    30961 tgatggggtt ttactgccgg gaggattctc ctatggtgac tatttgagat gcggtgcgat
    31021 tgctcggttt tctacaatca tggaagaagt gattcgtttt gctgaagaag ggaaaccagt
    31081 attcggtaca tgcaatggat tccagatatt gacagaagca ggacttttgc caggtgtact
    31141 gagacgaaat gagtctttgc attttatttg caaaactgta ccattgaaag tcaaccccaa
    31201 gacggccttt acttcagagt atgaagccga cgaaataatc tatcttccag ttgctcatgg
    31261 ggaaggaaat tatttctgtg acgaagaaac acttcaagaa ctaaaaaaaa ataatcagat
    31321 tgcctttact tataatgaca acatcaacgg cagcgtggaa aacattgcag ggattacgaa
    31381 caaagcaggg aatgtgttag gaatgatgcc tcatccagaa cgtgcagtag aagacttgct
    31441 aggatcagaa gatgggaaac ggttctttgc ttccatttta aaaaacttcg gaaaggtgac
    31501 cgtatagatg aaaacattga aagaaccgac agctgaagag atcaagaaaa aaagaatcta
    31561 tgccgaatgg ggattgactg atgaagaata tcgaatgatc gaagaagata tcttaggaag
    31621 aatgcctaat tatacggaaa ctggactgtt ttctgttatg tggagcgaac attgttccta
    31681 taaaaattct aaaccggttc tacgcaaatt tcctactagt ggacctcatg tgttgcaagg
    31741 ccctggagaa ggcgcaggca tcgtcgacat cggtgatgga ctagcagttg tcttcaaagc
    31801 agaaagtcac aatcatcctt cagccgtgga gccttatgaa ggagctgcga caggagttgg
    31861 cggaatcatc agagatattt tcagcatggg ggctcgtcca attgcgttgc tagattcatt
    31921 gaggttcggc gaattagata atccaagaac gaaatattta ctagaagaag tagttgcagg
    31981 tatcggcgga tacggcaatt gtatcggcat accgactgta ggcggcgaaa ttgcatttga
    32041 tccttgttat gaaggaaacc cattagtcaa tgcaatgtgc gtaggtttga ttgaacacaa
    32101 acatatccag aaagggcaag ccgctggcgt cggtaattcg atcatgtatg taggtgcaaa
    32161 aacaggtcgc gacggtatcc acggagcaac ttttgcctca gaagaattta atcaagaaga
    32221 agaacagcaa cgttctgctg tacaagtagg cgatcctttt atggaaaagc tgctgcttga
    32281 agcgtgtttg gaattaatct tgcatcattc ggattctcta ataggtatac aggatatggg
    32341 agcagcagga cttgtttcat ctagtgcgga aatggcttca aaagctggct caggacttat
    32401 attgacatta gatgaagtcc cacaaagaga aactgggatg acaccttatg aaatgatgtt
    32461 atcggaatca caagaacgga tgttgatttg tgttaaatca ggagaggaag aaaaaatcca
    32521 agaactattt cagaagtatg atctagatgc agtcactatc ggtaaagtaa cagacgacgg
    32581 gcaatatcgg ctatatcatc aaggagaaga agtagcaaat ctgccagtcg atgcattagc
    32641 tgaagatgca ccagtttatc ataaagaaat gaaagaacca gctcgaatcg tagaatttca
    32701 gcagttagct ccttatcagc cagttatcga agaacctgga caagtattgc ttgatctgct
    32761 gcagcaaccg acgattgctt caaaacgttc aatctacgaa acttatgatt cacaagtaca
    32821 aaccaataca gttgtccgtc caggaagcga tgctgctgtg atgagggtta gagggacgaa
    32881 taaagcgtta gctatgacca cagactgcaa cgcgcgctat ctgtatttgg atccaaaaat
    32941 cggaggacaa atagcagtgg cagaagctgc tagaaatatt attgctagcg gtggtaagcc
    33001 cttggcgatc accgactgcc tgaactatgg ttctcctgat aaaccagaag ttttttggga
    33061 attatcgact tcagctgacg gaattgctgc tgcgtgtgaa acgttaggaa ctcctgttat
    33121 ttcaggaaat gtctctttat ataatgaaac ggatggtcaa gcaatctatc caacaccaat
    33181 gattggtatg gtcggattga ttgaggatca taaacatatc actactcagg aattcaaaaa
    33241 atcaggggat ctaatctata tattaggtaa gacgtttgca gattttgatg gcagtgaatt
    33301 acaaaagatg cagcttggaa gaatcgaagg tgtgatccga aactttgatc tatccattga
    33361 aaagagaaac caagagttag tattgacagc catccaaaac ggattgattg aaagtgctca
    33421 tgactgttca gaaggtggct tggcaattgc actggcagaa tcagctttca aacatcagct
    33481 agggatatct gtacagtttg aattgtcctc tgctcaatta tttgcagaaa ctcaatcaag
    33541 atttgtgttg acagtcgcac cggaaaataa gacacgattc gaagaaatga tgggagatgc
    33601 tgctgtttta gcaggtaagg tgacggatga agcgataatc gaaatttcag caactgacgg
    33661 tcagatcaaa atagaaactg cagtagcaag aaagtgctgg gaggatgcaa tcgtatgtct
    33721 tatgaagtga agagtttaaa tgaagaatgc gggatcttcg gtgtttgggg tcatccagac
    33781 gccgctagtg tggcatactt cgggctccat agtcttcagc atcgaggaca agaaggtgca
    33841 ggtatcgtgt ccaatgatcg aggaaagctt aaggggcatc gagatttggg gctgctttct
    33901 gaggtattca aagatcaaag aaaattgcag cagttaacag gagaagctgc aatcggacat
    33961 gtacgttatg caacagcagg caatggaagt gtggacaata ttcagccttt tctattcaaa
    34021 tttcatgatc agtcgatcgg cttagcgcat aatggtaact tgatcaatgc tcgttccctt
    34081 agaaaagagt tagaggaaaa tggggcgatc ttccattcta actccgatac ggagatattg
    34141 atgcatttga tccgacgaag tgaagaaaca gattttttaa ataaattaaa aagtgctttg
    34201 aatgaagtca aaggtggctt tgcctattta ttaatgacag aaacggcaat gattgccgct
    34261 ttggacccaa atggttttcg tccattagca atcggacaaa tgaaaaacgg agcatacgtg
    34321 attgcctcgg aaacttgtgc attagaagtt attggggcac gttttataag agatgtccag
    34381 cctggtgaga tagtgatcat caatgacgaa ggaatccaga ttgattgctt tacgaaggac
    34441 acgcagcttt ctatttgttc gatggaatat atctattttg ccagaccaga ttcaaacatc
    34501 gcagggatca atgtgcatac tgcacggaaa aatatgggac ggaatttagc gaaagaatcg
    34561 ccagtaaaag cagatatggt cgttggcgta cctaattctt ctttgtcagc cgcaagcggt
    34621 tatgcggaag ctagtggaat cccttatgaa atcggattag taaaaaatca atacattgcc
    34681 cgaacattta tccagccaac gcctgagcta agagagcaag gtgttcgaat gaaattatct
    34741 gctgtacgag gagtagtgga aggtaaaaag gtgattatgg tcgatgattc aattgttcgg
    34801 ggtacgacaa gcagacggat cgtccatctt ttgaaagaag caggggcaaa agaagtccat
    34861 gtgaggattg cttctcctcc tttgaaatat ccatgttttt acgggattga tattcaaacg
    34921 cgtaaagaac tcattgcggc aaatcacacg attgatgaaa tcaaagaatg tatcggtgca
    34981 gattctttag gttttttaag tgaagagggt ctgatcgaat cgatcggtct ggaaaaagat
    35041 gctccgtatt caggattgtg tatggcttat ttcaacggag attatccgac gccgttatat
    35101 gactatgaag aaaaatatca ggaatcacta aaagaaaaag tatcgttctt ttaaaagcag
    35161 accaagaagg gagtatatga attcaatggc aaatgcatac gcaaaagctg gcgtagatgt
    35221 cgaagctgga tatgaagtag tagaacggat caagaagcat gtcaaaaaaa cggaacgttt
    35281 aggtatgatg ggcgctatag gaggattcgg cggttgtttt gatttatcgg tctttcaatt
    35341 aaaagagcca gtccttgtct cggggaccga tggcgtgggg acgaaattag cagtggcaat
    35401 cgaagcagac aaacacgata caatcgggat cgactgcgta gcgatgtgtg tcaatgatat
    35461 cttagcacaa ggcgcagagc cgttatattt cttagactac ttagcaacgg ggaaaaatga
    35521 tccgttacgt ttggaaaatg tagtaaaagg tgtagcagat ggatgtgttc aaggaaatat
    35581 ggcgctgatt ggcggagaaa cagctgaaat gcctggtatg tactcaggta atgattatga
    35641 tctagccgga tttgctgtag ggatagctga aaaatctcaa ttattgacag gagaaacgat
    35701 caacccagga gatgtgttgc ttggaatagc atctagcggg attcattcaa atgggtactc
    35761 tcttgttcgc aaaattttct ttgagcagca gcagttttct ttatcatcaa aactgccaga
    35821 attgaaaaaa acacttggcg aagaattgct tgagccaacg aaaatctatg tttcttcctt
    35881 gcttccgctg atcaaagaaa agaaaataaa aggagctgca catatcactg gtggagggtt
    35941 tgtagaaaat atcccgcgaa tgttaccaga atctatggct gcacaaatca aacttggctc
    36001 atggccgatt cttccaatat tcggctgttt acaaaaatat ggtgaaattc ctgagatgga
    36061 gatgtatgaa atcttcaata tgggcatcgg tatggtcctg gcagtcgaag aatcgaaagt
    36121 aaaagaaata gtacacgaaa ttgagcaagc tggcgaaaaa gtttatgaaa tcgggaaagt
    36181 gatcgccaaa gaaaaacatc gtgtggtgtt tataggagaa gaacgatgag aatcgctgtt
    36241 tttgcttctg gaaacggaag caactttcaa gcgctagccg attatctatc gaaaaaagga
    36301 ttggaatctt cgattgactg gttgttttgt gatcagcctg aagcatatgt tttgaaacgt
    36361 gcaactgcgt tgagtgtacc ggcagattgt ttttcaccta aagaatttga ttcaaaaaaa
    36421 gagtatgaag aagcaatttt gcataaattg aaagaaaaaa agatcgattt gatcgtatta
    36481 gctggatata tgcgaatcat tggaccggta ttgctgaaaa attatgataa aagaatcatc
    36541 aatatccatc cgtctctttt acctgccttc cctggtttgc atggcatacg tgatgccttt
    36601 gaagctggag taaaagaaac gggtgtcaca attcattata tcgaccaagg tgtagatact
    36661 ggaccaatca tccggcagga aaaagtgaga attgaacagg aggacacgtt cgattcttta
    36721 gaagaaaaaa tccatagagt agagcatcga atctatccag aagtgattag tgaaattatt
    36781 gaaaatggag gctatctgaa atgacaagag cattgatcag tgtatcagat aaaactggga
    36841 ttgtagcatt cgcccaaggt ttgattgaac aaggagtaga aatcatttca acaggaggaa
    36901 caaagcatgc gttggataaa gctgggatca aaacgctttc gatcgaagaa gtgacagggt
    36961 ttcctgaaat gatggatggc cgtgtcaaaa cacttcatcc taaaatccat ggtggtcttt
    37021 taggaagacg cgatctccct agccatatgg aggcaatgga aacggaaaat atccaaccaa
    37081 tcgactttgt ttgtgtcaat ttatatcctt tcaaagaaac gattatgaaa ccagatgtcg
    37141 aaatagcaga agctattgaa aacattgata tcggtggtcc tagtatgctc cgtagtgcag
    37201 caaaaaacca tgaatttgtc acctctgttg ttgatccatc tgactatgaa gaagtacttt
    37261 cagaattacg tcagtatggg catacttcac tttctttcag acaaaaacta gcggcaaaag
    37321 tctttcgtca tactgcggca tatgatgcac tgatcgctca atacttaacg gattgggtgg
    37381 aagaaaaaga accggaaaaa ttgacactta cgtatgaacg aaaacaaacg cttcgttacg
    37441 gtgaaaatag ccatcaagcc gctgcctttt atcagtccgc tcttctggaa aaatattcga
    37501 tcgcagcagc aaaacaactc catgggaaag aactttctta taataatatc cgagatgcag
    37561 atgctgcgct acggatcatg aaggaatatg acgagccaac ggtagtcgcc ttgaaacaca
    37621 tgaatccttg tggtattggg acagcatcta cgattttaga agcgtgggaa gcagcgtatg
    37681 aagcagatcc tgtttcaatc tttggtggga tcatcgtttt gaatcgagaa gtagatctgc
    37741 caacagcaga acagatgcat aagctgtttc tagaaatcat cattgcccct tcttatacac
    37801 aagaagcttt ggaattactg caaaaaaaga aaaacatccg attactgaca gtagactttg
    37861 cgcaggaaga aaatcaaaat cgagaagaaa cggtctcagt cttaggtgga cttcttgtac
    37921 aagatcaaga tctggcaata gaaaatgaag aagagtggaa agtcgtgaca aaacgtaagc
    37981 cgactccagc agaagcaaaa gcattagtgt ttgcttggag agctgtcaaa catgtgaaat
    38041 ctaatgcgat cgtactggca aacgaacgtc agacagtagg aatcggagcc gggcagatga
    38101 atcgagtcgg ttcagtaaaa attgcgattg aacaagcgca agagaaaatg gaaggtgcag
    38161 ttttagctag cgatgcttat tttccaatgg atgattcggt tgaatatgca gccaaacatg
    38221 gtataaaagc aatcattcag ccaggaggaa gcatcaaaga ccaagattct attgatatgg
    38281 cgaataaata cgatctagca atggtcttta ctgatgttcg gcattttaga cattagagag
    38341 gagtcggata aatgaacatt ttggtgatcg gtgcaggtgg tcgtgaacat gcaataagta
    38401 aaaaactttt agccagtccg aaggtggata cggtgtattg tgcgccagga aatccgggga
    38461 tgacaaaaga tggtatcaat tgtgtcgcta tcagtgagcg agatcattca gcgttaatcc
    38521 attttgttaa gaaagaggct attgattgga gtatcgttgg tcctgaagtt cctttgttaa
    38581 atgggatcgt cgatgatttt atggcggaag gattgaaaat cttcggtccg acaaaagcag
    38641 cagctctgat cgaaggttcg aaaagttttg ctaaacaatt aatggatact tatcaaatcc
    38701 cgacagctaa atccagaagt tttgaatgtt acgaaaaagc agcagcgtat atcaaagaaa
    38761 atggtgcgcc aatcgtagtg aaagcggacg gcttagcagc tgggaaaggt gtagtcgtgg
    38821 ctaccacagt gaaggaagcg ctggatgcgg cagaacaaat gttgaaccag catcgatttg
    38881 gggatagtag caaaaaaatc gtcgtagaag agtttttggc aggagaagaa ttctcccttt
    38941 tggcgtttgt ccgtaatacc aaggtgtatc cgatggtcat ttcgcaagat cataagcggg
    39001 catttgataa cgataaaggg ccaaatacag gcggaatggg tgcttattca ccagtaccgc
    39061 aaatttcaaa aaagatgatt gaaaaagctg tggaagaagt tttaaaacca gcggctttgg
    39121 gaatgaaaga actaggacgc tctttcacgg gtgttttata tgcgggtttg attgctacga
    39181 aggaaggacc aaaagtgatc gaattcaatg cgcgtttcgg tgatcctgaa acgcaagtcg
    39241 ttctttctcg gttgaagagt gactttgcgc aagtaatcga tgatttatta gagaatcgta
    39301 cagtagagtt aaagtggcag caagaaggat acaatgtagg cgttgtggtt gcagctgccg
    39361 gttaccccga agaatatgag acaggaatgg ttctaccaga ttttctggaa gaagagcttt
    39421 ctgtttacta tgctggagtt tcctcaaata acggcaaact agttggagca ggaggacgtc
    39481 tttatttagt agaagcatac ggtgagacga tcaaagaagc acagaaaaaa atttacaccg
    39541 cgttaatgga taaaacgaca gatggaacat tttatcgtac agatattgga gaaaaagctg
    39601 ccaatagcga actgatcgtg aagtaaatca gctgcttcca tttataaaaa atacaacaaa
    39661 cataatcgga agcgccgatt ttagtgaagc cttttcataa agagtgtggt acacttttgt
    39721 tgtgtatata aataaggagg agttcagatg aaaaaaattc aattaggtac ttctgatcag
    39781 aaagcagctg cagtgatctt aggctgtatg cgtatcaaca atgcggaaga tccagtaaaa
    39841 gtgattgaga cagcttatga aaacggcatt gatttttttg accatgcaga tatttatgga
    39901 aacggtgaat gtgaagaaat ctttgcagat gctctagcaa aaacatcaat caaacgagaa
    39961 gatcttttta ttcaaacaaa atgtggaatc gttccaggtg tgatgtttga tttttctaaa
    40021 aaacatatca ttgaatctgt agaaaaaagt ttgacccgtc tgaaaatgga ttatgtggat
    40081 gctttacttc ttcatcgtcc agatacattg gtagaaccag aggaagtagc tgaagcgttt
    40141 gatgaattgg aacggtcagg aaaagttcgt tattttggcg tcagcaatca aaaaccaatg
    40201 caaatcgaat tgctgaaaaa atatgttcgt caaccattag tagctaatca gctgcaattt
    40261 ggcttgaaac atactggaat gatcgatcaa gggattcatg tcaatatgac agatgaagca
    40321 agtatcgatc atgacggtag tgtacttgat tattcccgat tgcatgatat gacgatccaa
    40381 gcatggtcac cataccagta tggatttttt gaaggtgtat ttatcgggaa cgaaaaattc
    40441 cctgaattaa accaaacatt agaagaacta gcagctaaat atcaaacgac accaactggc
    40501 ttggcttctg cttggatttt acgccatcca gccaatatgc aagtgatcgc cggtacgatg
    40561 aacgtagggc gaatcaagga aatcgctcaa gcttcagaaa ttaatatgtc tcgggaagat
    40621 tggtacgaat tgtaccgtgc tgctggaaac attttacctt aaagattgtc ataagcaggt
    40681 caaaagggct ataaattaaa aagacagaat aacttgaaag ctgttttcag cttcgagata
    40741 ttctgtcttt ttttattgca aatggaaaga gtatcattgt acggatttcg tttattagtt
    40801 atttttgttt ttaaggaaaa gctgtgtccg atattctttt ggagaaatcc cttgtttttt
    40861 cttaaataaa taactgaaat agttagggtc attataacca atttcaaaag caatatctga
    40921 aatacgatag tctgattgct gcaataattt ttttgctaat tcgattcttt gttctgtcag
    40981 ataatcgatg aatgtttggt taaacgattg agaaaaaatc gtactgaaat gagagggact
    41041 taatgcaact tgttgagcga cccaagttaa ggacatatct ggatcggtaa aattttcttt
    41101 gataaaatcc aatgcatggt tcaaaattgg ctgatatttg ttccttgaag gctgtgaggg
    41161 cagagcagtt aagaaagaaa tgaacatata aactgtcgaa cggtaaagcg agtcgtcggc
    41221 gctgattgct aagcgttgac tggtggatgt gcaatgaacc atttcttgcg ggattttctt
    41281 ttctttcagg cagacatgct ggagtagctt agtcaagaca aataaacgat ataatcgtgt
    41341 tcgagttggt gtgccttgtg gtttcgtcaa gtgttcgatg tacttagata cttcgttttt
    41401 cgataatgaa gacaaatcaa gtgagaggtc aaagtaaaag acagaatcaa ctggaagttt
    41461 cgcttcttga atcaaatcct catagctgat aatttgttct ttaagggaac tggcggtttc
    41521 aagtatcatc tgcgtgatct caaaagatgc aggtaattcg ctgattcttt ctgcgacagg
    41581 accaatggcg acagaaaaat tatttttttg tcccttttct aattcatgga ccaacgtttg
    41641 ggctacctga taactggtct cgatcacatt ttcttcaaga gaatcaacta ttaaaaattt
    41701 gatgaatcga gaggaaacag cagagaagat cacttgttga ttctccctaa ataaaaactt
    41761 caaataatca ctgagatgag cgtaatcttc aaagtctgta ctgacttggt ttgctgctaa
    41821 taatacggtc atttttttcc ctgctaaaga gcgattgaaa gattcagcaa gtttcaatgt
    41881 ttcactgatc gtaagtgagc ctttgaacaa accgttcaag aaatgatttt ttttcaattc
    41941 gaaaacaaga tcagaagaag tgtgcgtttc tttttgctgc aaatctaaag cagttactgc
    42001 tttttctatt gcttgtttca attcgctact tttaatcggt ttaagcagat aatcatctgc
    42061 ctgtacctgg attgctcctt tcatataatc gaaatcgtcg aatccactaa taaatatgag
    42121 acgagtccaa ggaagtagtt tccttgcttc ttttgaaaaa gtcaacccgt ccatgaaagg
    42181 catttggata tcagtcagaa tgatgtcggg ctgtaagtcg ataattgaag acagtgccat
    42241 ctcaccatct ccagcttcgc cgacataagt gattggataa taagaaccaa ggacagttat
    42301 ttgttcccgc aagttattgc gaatgaggta ttcgtcttcg atgataaaaa ctttatacat
    42361 gtttgtttcc tccaattgtt ttgggagata gagggatcat cagtgtgaca gttgttcctt
    42421 ctcggtattt gctgtcaatc gtgataggtt tttgatcatt tccgtaataa agaaggagac
    42481 gcttgtttac gttgtaaagt ccgtagccga tactgaaatc tgaatcgatc cctttggcta
    42541 actctttacg tatttctgcc agtttttctg cagggatgcc aatcccgttg tctataactt
    42601 tgaattggat catctcatca attttgcatg tggtaatacg aataaatcct ttgtgacgga
    42661 cgtacttcgt tccatggtat acagcatttt caatcaatgg ctgcaagatc atttttaaaa
    42721 tagaaacagg aaaaagtgtt tctggtatat cgatcttata gtcaagcata tggccgtatc
    42781 ttatttttaa gatgactaga taatcattga tatggctaat ttctttttca agaggaatcc
    42841 agtcttgtcc tttgcttaaa gacgtacgaa aaaagccgga aagtgcatgg gtcatagtca
    42901 gagcttcttc aaagcagtct tgttcgatca aagaaataat ggcatccaaa ctgttataaa
    42961 taaaatgggg agtaatctga gcttgcaata cacgaacttc actttgtgct aaatggtatt
    43021 gtttcaaagc gttctcccgt aaagactggt ttagatcttc cgccatttta ttcatgctag
    43081 cggtaagtgt ttgtaattcc agtgtttccg gcagggttaa acgaaagcca aggttccctg
    43141 aagaaagttg ttctgacatc tcgatcagct gattgatcgg ttcttggacc tttctctcta
    43201 aaaagcgacg attctttttc gcatagaaaa aaatggtact aagaactcca agttccacta
    43261 ttgttaatag aatgagcgag cggacaagtg tcgtattttt tttgcttgct aagtcgatct
    43321 ccacacgaac aaaatcttgt aagatatctg acagcagttg agtgacagaa tctacctgat
    43381 tgatgatctc ttcattggta tccataaaat cttttgccaa gatattattg atcagctcgt
    43441 tttgataatc ttccagtgta tcgatcgtac gtagcgatac atctaacgta ctaatttctt
    43501 taagtgtatt tgtattattt ttgctctctc gaatatcatt cctaagttct tctaggatat
    43561 tttcctcatt gaactcatct acggttactt ggccagaaat caagtcccac atactttcca
    43621 aaactttttg atcaaccttc aaagcaattg catctgcttt ttggatattt gcgatcgtct
    43681 gttgataaat caaaagctgt tgcgaatata acagtatgct cagtagcaaa gggataacag
    43741 caaatagaag catggctttg tttgcttggg caaaaatctg ttttatgctt aaattttttg
    43801 tcatgatact tctccagtca ataatttctg gttgggatgt tagctatatt ctgctgggaa
    43861 aagacagtct cggaaataaa aatatcttta ggtaatgttt ttcctgtttg aatatttcca
    43921 aaataacgag taacggtatt ggctacatac cagccgacat caggtttaca ctcgactaca
    43981 caattgacga ttcctgagcg tagcttctcg atcatatctt cttgtccatc aatagttaca
    44041 atgatcaaat cttctccagg tttgattgat gtttctttta tcgcagctaa agcaccgtga
    44101 gtcatttcat cactatggct gtataataca tcgatttcgg ataaatcatt tgtttctaaa
    44161 tatcgtttca tctggtcttt tcctttcatc cgaataaaat caccgacaat tcggtgaaca
    44221 atagtcatcg gaggtttatg gtcgatggtt ccatcttttt ttagggttgg tttacgattg
    44281 attgattcca aaaatccttc ggagcgtagc ttggtcggtg tggagttctc tgaaccagca
    44341 agttctagga ttctgatttc ctgtttcttt gaatttgtga agtgattgct gacaaataaa
    44401 cccgcccgat ttccttctgc tttgaaactg gggccaatgt gggtgacgaa aagctcggga
    44461 tcattcgttt gaatatgtct gtcgacaagt atgacaggga tccctgctcg ctttgcttct
    44521 tttaatacag agtcccaccc ggattcttgc aaaggagtaa aaatgatcat atccacttta
    44581 taggcaatga acgtccgtat atcttggatt tgccgttcct gattcatgta gccatttcgg
    44641 tagagaactt ggtaatcttc tttttcaagc gcagtgataa ttgattcagt atgctttttc
    44701 cgccagctac tctccgttcc tgattgcgaa aaaccaacga ctagtgggtc aggtgcttcc
    44761 tttgtattag gtgtacaccc catcatttgg taagcgatta caacaagggc taaaaaaaat
    44821 aaaacacgtt tcactttaaa tcactccatc tggatttgtt agtactatct tatcagataa
    44881 aagggaaaat caaagtcaaa aggaatcaat cgaaaaaaat ccaagaaact taaaaaaatc
    44941 caagacaaaa aaagtacacc taaaaaattt aaagtaaatc ccataaaaaa atcaatgtta
    45001 acgctttctt tattagctat actcggtgta tcaattgaaa tgggggataa aaaatgaaaa
    45061 acaaatttag aaagattgtt gggactatcg ctattttgac cgcaagcatt ctattaagtg
    45121 cgtgtggcaa ttcaggatct gcagatgata gtacggggta tgtaggaatc gctatgccga
    45181 ccaaatcagc agaaagatgg atcgctgatg ggaacaacat ggtctcggaa ttagaaaaac
    45241 tgggttataa aacagatctt caatatggag aagataaagt agaaaatcaa gtagcacaaa
    45301 tagaaaatat gattacaaaa ggggtagata cacttgtgat tgcttctatc gatggttcgg
    45361 ctttaactga tgtgttagct aaagcaaaag aagcagatat caaggtgatc gcctatgatc
    45421 gtttactgat gaattcagaa aatgtcgatt attacgcgac ttttgataat tttggagtag
    45481 gtgtatcgca agcagcttat attgaagagc acttaggatt gaaagaagga aaaggaccat
    45541 tcacgattga attatttggt ggctcgcctg acgacaacaa cgcactaatc aattacaacg
    45601 gagtgatgtc tgttttacaa ccatatatgg acaacggtca gttggtcgtg ccatctggac
    45661 agacgagttt cagtcaaatc gctacgcttc gctgggatgg ttctacggcg caagcaagga
    45721 tggataatct gttaagcgca aattatactg accaaacatt ggatgctgtt ttgtcgccat
    45781 atgatccaat aagtttagga atcatttcgt cattaaaagg cgtggggtat gggagtgaaa
    45841 gtaaaccttt acctgtgatt actggacaag atgcgacagt tgctggcgtt aaatcgatca
    45901 ttgccgggga acaaacacaa acgatcttta aagacacacg tatcttagca aaaaatacga
    45961 ttgaaatgat caaagcaatc agtgatggag aagaggttcc ggtcaatgat actgaaactt
    46021 atgataatgg ggtgaaaact gtccctacgt atttagcaaa tacagtatct gtcgataaag
    46081 ataattatca agcagagctg atcgacaccg attattataa agaatccgat ctgaaaaatt
    46141 aagaggaacc aaacaaggaa ctaaagagat ctaagtcaga gagaggataa gaattatggc
    46201 ggattgtatt ttaaaaatgg cagatatcac caaaaaattt tctggaatcc gagcgttaga
    46261 ttgcgtgaat ctgatgattg aacgtgggga aatccatgca ttgtgcggag aaaacggagc
    46321 gggaaaatca acattgatga atgtcttgag cggcttgtat ccatatggct cctatgacgg
    46381 ggaaatcttt tatgatggaa agctgtgtca atttaaagat ttgaaagata gtgaagaaaa
    46441 aggcatcgtc atcattcatc aagaattagc actaagtcct tatctttcaa taaaagagaa
    46501 tatttttctc ggaaatgaac aagcagaaag aggcgtgatt gattgggaac tgacagaaaa
    46561 gaaaacatat gaactgctga ataaagtcgg tttgtctatc gacccgaatc ttctagtatc
    46621 ccagattggc gtagggcaac agcaactagt tgaaatagct aaagcattat caaaatccgt
    46681 ccgtctgttg attttggatg agcctaccgc tgcattgaat gaagaagaaa gcgcgaattt
    46741 gctgagattg atccgagagt tgaaagagca aggtgtaacc tccatcatta tttcacataa
    46801 gctgaatgaa atcgtggata tcgcagatcg aatcaccatt ttacgggatg gacagacgat
    46861 tgagacacta gaaaatgaaa tgatcagcga agagcatatt attcgcggaa tggtgggcag
    46921 agatttagtt gatcgttatc ctgaaagaaa accggatatt ggagaagttt attttaaagt
    46981 agaagactgg acggtctatc accctcttga tcacgagcga atcataaacg accacatcaa
    47041 cttgcatttg aaaaaaggag agattgtagg aatagctgga ctgatgggag cgggcagaac
    47101 tgaattcgct atgagtctat ttggacattc ttatggaagc aagatatccg gacgtatatt
    47161 aaaggaaggg gcagagatat cagttaagac cgttccttca gccattgcaa acggactcgc
    47221 ttatgtctcg gaggaccgaa aatctttagg actgaatctg ctgatggata ttcgggaaaa
    47281 cgtgacgctg agcagtttgg ataaaataag tcaaaaagga gtattagata aagaaaaaga
    47341 agtaactgag gcagaaaatt tccggaaaaa gatgcgtata aaaacaaact ccatccatca
    47401 aattgtcagt agtcttagtg gtgggaatca acaaaaagtc gttttatcca agtggctgat
    47461 gacacaaccc gatattcttt ttttggatga gccaacccgt gggatagatg ttggggcaaa
    47521 atatgagatc tacacgatta tcgaagaaat ggcagcaaat ggcaaagctg tctgtcttat
    47581 ctcttctgaa cttcctgaaa tattagggat gtgtgatcga atctatacga tgaacgaagg
    47641 acgtattaca ggagaagtct cgcgagaaga tgcagatcag gaagtcttga tgaaattaat
    47701 gacgaaagaa gaggtgggtt aagttggaac aggcaaaaaa tcttacggat aaaaaagaga
    47761 aaaaactaaa tttgaaaagt agagcagctg atctttttgg tcgctacagc atggtgatca
    47821 ttttagcggg actacttatt gcgtttcaat tgatgacgga tggtattttc tggcgtccat
    47881 tgaatataac taaccttgtt ctgcaaaata gccatatatt agtactagct gcagggatgt
    47941 tattagttgt gctcttaggt catgtggatt tgtcggtagg gtcagtgatg gcgtttgttg
    48001 gtgcaattgc gggcatgatg atggtcaatc gccaaatgaa cccgtggatg acagttatcg
    48061 catgtcttgc agtaggcggg ctgatcggcg catggcaagg tttttgggta gcttatgcag
    48121 ggataccggc gtttatcgtg actttagcag gattgctgat gtttcgtgga ctgacacaag
    48181 ttgttctagg aggccaatct ctagcacctt ttccagctgt tttccaaaaa atgtctacgg
    48241 gttatttacc agacttaagc gaaggaagca gccttcactt cttgacattg attttaggaa
    48301 tgatcatcac gatcgtgtta gttgttggtc aatggcgaac aagaaatcgt cggaaaaatc
    48361 atttatttga agtggaatct ccaacagctt tcttggtaaa ggcggtattt acagcagtcg
    48421 ttgtactagg aataacttat atctttgcct cttatcaagg gtatccgatt attttgatca
    48481 ttcttggttt gatcgttgca gcatatgggt ttttgacaaa taaaacagta gcaggtcgac
    48541 agatttatgc gacgggcgga aatcgaaaag cggctgaact atcagggatc aaaacaaagc
    48601 gaatcacgtt ctgggtattc gtcaacatgg gagtcatggc agctttagct ggattagttt
    48661 tagctgctcg attgaatgcg gcaacacctc aagcaggtac atcgatggaa ctggatgcaa
    48721 tggcggcagt atattttggt ggtgcttcga cttccggcgg cattggaaca atcatgggtg
    48781 cgattgtcgg tggcttggtc atgggtgtat tgaacaatgg catgtcgatt ttaggcgtcg
    48841 gggtagactg gcagcaggca atcaaaggat tgatcttgct tttagccgtt gtgctagact
    48901 tgtataataa gaaaaaacga acaacgtagg agaacgccgg ttattcagaa aaaagactgt
    48961 gacaagacat ttgtcacagt ctttttttcg ctaaaagcga acattcattg tttcgtttgt
    49021 atagactaaa aataatatat gtttttttac cattcgtata aattctcttt ttgctcttga
    49081 tttttttgct taattgagtt aaattacata gggcgctaaa aaaagccttg attaaattaa
    49141 taatgttcgt gttttgctgg atgtgaacat caggaggata atgtaatgaa agtatttgat
    49201 tacgaagata ttcaattaat tcctaataaa tgtatcgtaa atagccgttc tgaatgtgat
    49261 acaacggtca cattaggtaa acatacattc aaaatgccag tagtgcctgc caacatgcag
    49321 acgattattg atgaaacaat cgcagaattc ttagcggaaa atggttattt ctatatcatg
    49381 catcggtttg atgaagcagc tcgaattccg tttatcaaaa aaatgaaaaa gcgtggattg
    49441 attacctcga tcagtgttgg cgtcaagaaa gaggaatatt cctttataga gaagttggca
    49501 gaagaatcgc taaatcctga ttatatcact atcgacatcg cgcatggaca tgctaactca
    49561 gttattgata tgattcagca tattaaaaaa tatttgcctg aaacttttgt gattgccggt
    49621 aatgttggta caccggaagc cgtccgtgaa ttggaaaatg cgggcgcaga tgcaacaaaa
    49681 gtcgggattg gtccaggaaa agtatgtatt acaaaaatca agacaggctt tgggactgga
    49741 ggctggcaac tggcagctct tagatggtgt gcgaaagcag ctcgcaagcc gatcatcgct
    49801 gacggtggga tcagaacaca tggcgatatt gcaaaatctg tccgttttgg tgcgacaatg
    49861 gtcatgattg gttcattgtt tgccggtcac gaggaatctc ctggcgaaac aaaagtcgaa
    49921 aatggaatcg tgtataaaga atactttggt tctgcttcag aattccaaaa aggcgaaaaa
    49981 cgaaatgttg aaggaaagaa aatctggatc caacacaaag gatctttgaa agatacacta
    50041 gtggaaatgc aacaagacct tcaatcatct atttcttatg ctggaggaag agatctggaa
    50101 gccattcgaa aagttgacta tgtcatcgtg aaaaattcga tttttaatgg agacacaatc
    50161 taaaaaataa ataaaatatt aggatgttgt gaaaaagttg tcctgcatta agtaataaga
    50221 acagccaaac aaaaatagtt ctttatatgt tttgtttggc tggaattatt atcgcagata
    50281 caagcttttg aacatcatta ttcagaataa gggactgtga taagattttt gtcacagtcc
    50341 cttatgtttt gcaaaaaaag tttttctttt ttctcgtaaa ttcggtaaaa tcaaaagaaa
    50401 aaatagacaa tagaaaagag aagcttatgt gggaaaaagt agagaaaaaa caaggaccga
    50461 tttatcgtca aattatggaa cagattatga gagaaatcga aaacggaagg atcaatcctg
    50521 gaagtcaact tgaatcagaa cgaaaactag ggcaactttt tggtgtgaat cgttccaccg
    50581 ttgtccatgc attggaagag cttagggagc ttggggtact aacgagcaaa cgtggcagcg
    50641 gatggtttgt taatcagact gaatggggga aattcgctgt tccaagaatc gattggcggc
    50701 aaatgatctc tcctcgttat gagcagacgg actggtatga gcaaaaaata agagaagcaa
    50761 agcagatcca aaaaacatcg tttcttgatt tatacgctag cgagatgcca gatgagcttt
    50821 tgccgaattt tgagtttcct tcttattctc ttgaagaaat cttagcggaa gaaaaagaaa
    50881 tggatctttt aggctatact ccgttacgta acaaaatcaa acggtatttg gaaagtaaat
    50941 ttgaattggc attttccccc aaccagcttc ttgtgactgg tggcggtcag caagcaatct
    51001 ttttgatttt acaaacgatt ctttcagctg gagaggggat agctgtagag tcaccttctt
    51061 ttttttaccg attacctctt ttcaaagctt caggaacgcg tttatttggg ataccgatgg
    51121 atgaagaagg gatcgactta gaaaaactga aagaatcgat ccataaaaat aaattgaaag
    51181 cagtgcttat caacccgaat tttcaaaacc ctacaggaaa agtgatgagt caaaaacgac
    51241 gagaaaagct agtagaattg tgtcgacagt atcggcttcc aattattgaa gacgatgtat
    51301 ttacggatct ttcatttcta aaccaagaag aagtccttcc tatacgaacg attgatccgg
    51361 ataatgtgtt atacgtcggt tcgttatcta gggttttagg aaaaacaacg aaaatcggtt
    51421 gggtgatagg acctgagact tttatctcgc aactagctca agcgcaagaa atgatggagt
    51481 tttcgatgaa tatccttaca caaatcacag tggctaatgt atttaatgaa gcaattgatt
    51541 tgaaaatgca agatgtaaga aaaaagttga aagaaaaaag ccgactgata agcgcttggg
    51601 gagattcaca atcgtttttc aagcttcatt caattttagg tggttactat gcctggatta
    51661 cttgggatgg gaaaaaacta gaccccgaac tagcagaaaa agtagtagat atgggtcttg
    51721 gaattgcacc aagtctactt tttgggcaag atataaatgg aatcagaatc aattacagta
    51781 ggctggatga aaaccaaata ccgttgtttt attcaaagat gaaaattcta gaaaagtggt
    51841 taacagaata atttcacaaa gtaaatagat taaagaatat aacagcttgg atttaaattt
    51901 caagctgttt cttttttttc ggaaaaagaa tacgatataa agaaactaag aaaaaaccat
    51961 tatttgtacg tccgttcacg atgtgtaaat aaaataaatg tttgcaacaa aactgtataa
    52021 caccaacgtt tttaaataga aacagatggt tgtaagtttg attagaaaat agaaaaaatg
    52081 cagatgaaat ataaaacgct ttccttattg tgattttatt cactaatgct gttaatatgc
    52141 ggattggcat aatttccttt catcgtgaaa atttgtgctt ttagcttgta tttctcataa
    52201 atccatgata atttattaat gaagacggtt aaatagtgat acagttttat tcactgtttc
    52261 aatcgcagaa tgaagagatt ttcttataga tgagagagga atgtgtgaca aatggcaaac
    52321 aaaaaagcac cgatcgactt ccaagcactg ctagatgaag tcaatgcaga tttcccagta
    52381 tatcaagcac ttgatcaaga tggaaacgta gttaacaaag atttagtacc tgatttatcc
    52441 gatgatgaac tcgttgaatt aatgactcat atggtatggt ctcgtgtatt agaccaacgt
    52501 tcaacagcgc tgaaccgcca aggacgccta ggcttttttg caccaactgc tggacaagag
    52561 gcaagtcagc tggctagtgc ttacgcattt gataaagaag atgttcttct tccaggttat
    52621 cgggatgtac ctcaactagt aaaacatggt ttacctttat ctcaagcttt tttatggtct
    52681 cgaggacatg ctgcaggtaa ttcttatccg gaagaattga aagctctacc accacaaatt
    52741 atcatcggtg cacaatatgt acaagcagcc ggtgttgcat taggtttgaa gaaacgaaac
    52801 aagaaaaatg tcgtcttcac ttatactggt gatggcggtt catcacaagg tgatttttac
    52861 gaagcaatca atttcgctgg cgcttaccat gcaaatgccg tattttatat ccaaaacaac
    52921 gggtatgcga tctctacacc tcgtgaaaaa caaactgcag caaaaacact tgcacaaaaa
    52981 gctgtcgcag ctgggattcc tggtattcaa gtcgatggaa tggatccgct tgcagtatat
    53041 actgtatcta aaatggcacg ggaatgggcg atcagtggaa atggaccagt cctaatcgaa
    53101 acactgactt atcgttatgg accacataca ctatctggtg acgatccaac ccgctaccgt
    53161 acaaaagaca cagatgacga ttggcagaaa aaagatccat tgatccgctt ccgtaaatat
    53221 ttgacggaaa aaggactttg gtctgaagaa aaagaagaac aagtcatcga agcaactaaa
    53281 gaagaaatca aagcagctat tgctgaagcc gacaaagtac caaaacaaaa ggtttcagat
    53341 ttcttgaaaa acatgttcga agtatctcca caatcaatca aagaacaaat tgcaatttat
    53401 gaagcgaagg agtcgaaata atcatggcac aaaaaacaat gatccaagca atcacagatg
    53461 ccttagcact tgaactagaa aatgacgaga atgtcgttgt ttttggtgaa gatgttggga
    53521 aaaacggagg agttttccgg gcaactgaag gattgcagga aaagttcgga gaagaccgag
    53581 tattcgatac tcctttagct gaatctggaa tcgcaggatt gagtttcggt cttgcgttag
    53641 aaggatttcg tccagttcct gaaatccaat tctttggttt tattttcgaa gcaatggacg
    53701 aagtagtagc tcaaatggct cgtacaagat atcgaatgag cggcactaga aatctaccca
    53761 tcacaattcg ttcgccattt ggtggcggtg ttcatacacc agaattgcat tcggataatt
    53821 tagaaggttt gatcgctcag tctcctggta ttcgagtagt gattccttcc aacccttatg
    53881 atgcaaaagg actattgatt tcttctatta gaagtaacga tccggttgtt ttcctagaac
    53941 acatgaaact atatcgctca ttccgagaag aagtgccgga tgaagcttac gaagttcctt
    54001 tggataaagc agcagttact cgtgagggaa cagatgtatc tattatcaca tacggagcaa
    54061 tggtgcgtga agcaatcaaa gcagcagaca atcttgcaaa agaaaatata tctgttgaaa
    54121 tcattgatct tcgtacagtt gcgccattag atgtagaaac gatcattcaa tccgtggaaa
    54181 aaactggtcg cgtagttgtt gtccaagaag cacaacgaca agcgggcgtt gccgcgcaag
    54241 tagtttctga gatctcagaa cgcgctatcc tttcattaga agccccaatc ggacgagttt
    54301 ctgcacctga tacagtcttc ccatttggac aagcagaaaa tgtctggttg ccaaatgcaa
    54361 aagatatcga agacaaagta aaagaaatcg cggaatttta agaaaagaag ggacgaaaca
    54421 aagtcatggc ttatcaattt aaatt
//
LOCUS       DBBGRF010000015        53706 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000015 DBBGRF010000000
VERSION     DBBGRF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.015"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            145..825
                     /locus_tag="ACIZD4_000987"
     CDS             145..825
                     /locus_tag="ACIZD4_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HGC5989938.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            915..1949
                     /locus_tag="ACIZD4_000988"
     CDS             915..1949
                     /locus_tag="ACIZD4_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HGC5989939.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1963..2298
                     /locus_tag="ACIZD4_000989"
     CDS             1963..2298
                     /locus_tag="ACIZD4_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989940.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2282..4762
                     /locus_tag="ACIZD4_000990"
     CDS             2282..4762
                     /locus_tag="ACIZD4_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989941.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4818..6377
                     /locus_tag="ACIZD4_000991"
     CDS             4818..6377
                     /locus_tag="ACIZD4_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989942.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQISYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6374..7738
                     /locus_tag="ACIZD4_000992"
     CDS             6374..7738
                     /locus_tag="ACIZD4_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HGC5989943.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7909..8979
                     /locus_tag="ACIZD4_000993"
     CDS             7909..8979
                     /locus_tag="ACIZD4_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989944.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            8994..9662
                     /locus_tag="ACIZD4_000994"
     CDS             8994..9662
                     /locus_tag="ACIZD4_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989945.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9682..10260
                     /locus_tag="ACIZD4_000995"
     CDS             9682..10260
                     /locus_tag="ACIZD4_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5989946.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10661..11572
                     /locus_tag="ACIZD4_000996"
     CDS             10661..11572
                     /locus_tag="ACIZD4_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGC5989947.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11950..12867)
                     /gene="rnhC"
                     /locus_tag="ACIZD4_000997"
     CDS             complement(11950..12867)
                     /gene="rnhC"
                     /locus_tag="ACIZD4_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGC5989948.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13069..13506
                     /gene="zapA"
                     /locus_tag="ACIZD4_000998"
     CDS             13069..13506
                     /gene="zapA"
                     /locus_tag="ACIZD4_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGC5989949.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13564..14112
                     /locus_tag="ACIZD4_000999"
     CDS             13564..14112
                     /locus_tag="ACIZD4_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGC5989950.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14227..16587
                     /locus_tag="ACIZD4_001000"
     CDS             14227..16587
                     /locus_tag="ACIZD4_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGC5989951.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16674..16988
                     /gene="trxA"
                     /locus_tag="ACIZD4_001001"
     CDS             16674..16988
                     /gene="trxA"
                     /locus_tag="ACIZD4_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGC5989952.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17170..18948
                     /gene="uvrC"
                     /locus_tag="ACIZD4_001002"
     CDS             17170..18948
                     /gene="uvrC"
                     /locus_tag="ACIZD4_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGC5989953.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTCQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19093..19992
                     /locus_tag="ACIZD4_001003"
     CDS             19093..19992
                     /locus_tag="ACIZD4_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989954.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            19985..21247
                     /locus_tag="ACIZD4_001004"
     CDS             19985..21247
                     /locus_tag="ACIZD4_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5989955.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21408..23306
                     /locus_tag="ACIZD4_001005"
     CDS             21408..23306
                     /locus_tag="ACIZD4_001005"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HGC5989956.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23636..24355)
                     /locus_tag="ACIZD4_001006"
     CDS             complement(23636..24355)
                     /locus_tag="ACIZD4_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGC5989957.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    24545..24592
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            24692..25024
                     /locus_tag="ACIZD4_001007"
     CDS             24692..25024
                     /locus_tag="ACIZD4_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989958.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25011..27014
                     /locus_tag="ACIZD4_001008"
     CDS             25011..27014
                     /locus_tag="ACIZD4_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HGC5989959.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27033..27503
                     /locus_tag="ACIZD4_001009"
     CDS             27033..27503
                     /locus_tag="ACIZD4_001009"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HGC5989960.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27524..28108
                     /locus_tag="ACIZD4_001010"
     CDS             27524..28108
                     /locus_tag="ACIZD4_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HGC5989961.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28123..29109
                     /locus_tag="ACIZD4_001011"
     CDS             28123..29109
                     /locus_tag="ACIZD4_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HGC5989962.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29099..29410
                     /locus_tag="ACIZD4_001012"
     CDS             29099..29410
                     /locus_tag="ACIZD4_001012"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HGC5989963.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29432..31213
                     /locus_tag="ACIZD4_001013"
     CDS             29432..31213
                     /locus_tag="ACIZD4_001013"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HGC5989964.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31206..32582
                     /locus_tag="ACIZD4_001014"
     CDS             31206..32582
                     /locus_tag="ACIZD4_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HGC5989965.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32589..33224
                     /locus_tag="ACIZD4_001015"
     CDS             32589..33224
                     /locus_tag="ACIZD4_001015"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HGC5989966.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33254..34609
                     /locus_tag="ACIZD4_001016"
     CDS             33254..34609
                     /locus_tag="ACIZD4_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGC5989967.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34801..36195)
                     /locus_tag="ACIZD4_001017"
     CDS             complement(34801..36195)
                     /locus_tag="ACIZD4_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGC5989968.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36287..37258
                     /locus_tag="ACIZD4_001018"
     CDS             36287..37258
                     /locus_tag="ACIZD4_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HGC5989969.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37255..38037
                     /locus_tag="ACIZD4_001019"
     CDS             37255..38037
                     /locus_tag="ACIZD4_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HGC5989970.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38206..38577)
                     /locus_tag="ACIZD4_001020"
     CDS             complement(38206..38577)
                     /locus_tag="ACIZD4_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC5989971.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38711..39154
                     /locus_tag="ACIZD4_001021"
     CDS             38711..39154
                     /locus_tag="ACIZD4_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGC5989972.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39197..40006)
                     /gene="yidA"
                     /locus_tag="ACIZD4_001022"
     CDS             complement(39197..40006)
                     /gene="yidA"
                     /locus_tag="ACIZD4_001022"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGC5989973.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40025..41392)
                     /locus_tag="ACIZD4_001023"
     CDS             complement(40025..41392)
                     /locus_tag="ACIZD4_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC5989974.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41376..42206)
                     /locus_tag="ACIZD4_001024"
     CDS             complement(41376..42206)
                     /locus_tag="ACIZD4_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HGC5989975.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42369..42806
                     /locus_tag="ACIZD4_001025"
     CDS             42369..42806
                     /locus_tag="ACIZD4_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGC5989976.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42882..43502
                     /gene="rpoE"
                     /locus_tag="ACIZD4_001026"
     CDS             42882..43502
                     /gene="rpoE"
                     /locus_tag="ACIZD4_001026"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGC5989977.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43691..44197
                     /locus_tag="ACIZD4_001027"
     CDS             43691..44197
                     /locus_tag="ACIZD4_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGC5989978.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44214..45113
                     /locus_tag="ACIZD4_001028"
     CDS             44214..45113
                     /locus_tag="ACIZD4_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HGC5989979.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45200..46084
                     /locus_tag="ACIZD4_001029"
     CDS             45200..46084
                     /locus_tag="ACIZD4_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGC5989980.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(46276..46347)
                     /locus_tag="ACIZD4_001030"
     tRNA            complement(46276..46347)
                     /locus_tag="ACIZD4_001030"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46312..46314),aa:Arg,seq:ccg)
     gene            46407..47741
                     /gene="rpoN"
                     /locus_tag="ACIZD4_001031"
     CDS             46407..47741
                     /gene="rpoN"
                     /locus_tag="ACIZD4_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HGC5989981.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            47890..48981
                     /locus_tag="ACIZD4_001032"
     CDS             47890..48981
                     /locus_tag="ACIZD4_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HGC5989982.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            49022..50023
                     /gene="gap"
                     /locus_tag="ACIZD4_001033"
     CDS             49022..50023
                     /gene="gap"
                     /locus_tag="ACIZD4_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGC5989983.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            50133..51323
                     /gene="pgk"
                     /locus_tag="ACIZD4_001034"
     CDS             50133..51323
                     /gene="pgk"
                     /locus_tag="ACIZD4_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGC5989984.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            51427..52182
                     /gene="tpiA"
                     /locus_tag="ACIZD4_001035"
     CDS             51427..52182
                     /gene="tpiA"
                     /locus_tag="ACIZD4_001035"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGC5989985.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            52298..53596
                     /gene="eno"
                     /locus_tag="ACIZD4_001036"
     CDS             52298..53596
                     /gene="eno"
                     /locus_tag="ACIZD4_001036"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HGC5989986.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        17817 a         9355 c        11349 g        15185 t
ORIGIN      
        1 gaatattcat gtaaacgatt ttattgtttt tttctctttt atacaaaaag ggtcataatt
       61 tcaagtaagc ggatgaattc atgaggattt tttgcatact gtctctacta tacttaggtc
      121 actaagaaaa aggagtgatt tattatgaaa aagaacatga ttgggacatt attactttca
      181 acacttcttc taggcggctt ggcaacacca gcttttgctg agggtcaagc gacttcaaaa
      241 ggagatatta cctttactga accaacaaat accgtggagc ctcttaaccc tactgatcct
      301 tcaaaaccag tagagccagc agatccggaa aatccagcaa ctggccagac aggtccttta
      361 acactggatg tagttcccga attgccattt ggtacacacg agattgaaag cggaacaaaa
      421 acgtatcaag tagacgcttc aaaaaacgat acaccttatc tccaagtatc agatcgtcga
      481 ggtgtaggtg cagatggcca agcacaaggg tggaacgtga cagtttcggt ttcagatttt
      541 gtaaacggtt cacaagtttt gcaaggcgct gaattagatt ttggaacatc cactgttaaa
      601 agtacgtcag ataacgaatc cactggacca actagtcaaa ctgtaactgg gttgagtaaa
      661 gcaagtgcag cgacaccaat atttacagca gcaaaagatc aaggtctggg aacatggctt
      721 tctgtttatg atccagcaaa tatcacactg aaagtgccga aagcagcagc tggaacattc
      781 acggctgatt tgacttggaa cctcgtggct ggcccagtag catagagtat gaaataaatt
      841 caacaaactg cggtgaaaat actataggtg aaggattttt taccgcagtt gttgttgaaa
      901 ggatgtggtg gacaatgaat caaagtaaac gactgtttgt ttcgtttttt tctattttaa
      961 gtctattttt catttttccg tcaatcagcc aagcaaagga ttcagcagga gactttggaa
     1021 tcaaaccggt atttccagag aaccaaatag ataaagcaat cggttatttt gatttattag
     1081 tggcaccgga acaaaatcag acactagaag taattatcag caattcttca gatgaagaac
     1141 gaacatttga ggtctctgtc aatccggcgg taacgagtga tggtggaacg atcgattata
     1201 gtcaaaaaaa cccaacgtta gatgagacat tgccgtttga tgtccgtgac gttttgctca
     1261 ttgcgaaaaa ggaaatcaat gtatcagcac atgcagaaac aactgtacct atagaagtga
     1321 aaatcccagc aaaaagcttt aagggacgtg tattagcggg tattcatgtt tcacctaaag
     1381 aagaagctga aacagaaaat gctacagaag gagcacaaat caaaaatcgt attgcttata
     1441 atctcgcagt cgttttacaa gaaagtcaag agacgataga accggatctg aaacttttat
     1501 caggagattt ggacgaggtc aacgcaaagc caactgttca gcttcgtttc caaaatcctc
     1561 agcctaggat tatcagcaat ttgatattta cgagcaagat cttttatgaa aatcagcttt
     1621 atattgaaaa tacgtctaat gcatttttag ttgcaccaaa ttcgaatttt cacttgaatc
     1681 ttgatttagc tggtgataaa gcaaaagccg gcgattaccg cgcagaaatc atagcaaaat
     1741 caggcgacag taatgaatgg cgatttacac aaaactttac gatcaaaaaa gaaaaagcac
     1801 aaaaagtaaa tgaaaattcc gtttttgcag tacaagaaca atctttccca tggctttatg
     1861 caggattggt tgctgcagtt ctagtgttat ggttgatttt gctgtttttg tgggtccaca
     1921 agaaaaagaa aaaaggagaa acaacatgat gaggtgattt cgttgaaaac atcgatctta
     1981 ttgggaggga ttattgcaag tttgctgttc ttcagctggc aagagccagt ccaagcagat
     2041 accaaaagtt caggtacgat tacattttat gatctaagtc caattccgca tccaagtggt
     2101 tcagtcaatg gcgcatcaaa acagcagaca cagctaccga tttataaaga atctaatcaa
     2161 catggcgtat tcccggagac gaatgaacaa aagatccgtt ttctttattt gatcattggt
     2221 atagaattat ggcttcttgc gtggttgttg ttatggagaa gaaaggaaaa ggaggatgaa
     2281 catgttgcta caaaataaat tttcattttt tcgctccttc ttttttactt cgctttttgt
     2341 tttaagtata tttatctttt caccttcggc agaagctgtt ggagcaacgc ctcctgccat
     2401 ttcttatgat ccatacacgt atgaaaatat cgtacctcca aatggtggac gtagtgcagt
     2461 caatggcggg aagcttgtcc aactaactgg ggctaaccaa ttgcctaaat tgactgctac
     2521 ttatttgaac gatggttcaa atgatccttg gaaaggtggc acggtccgtt ttcattggga
     2581 aagccatgtg aaactaacaa atgtacttga tttggtgaat atcactgcac aaggatttgc
     2641 atttgtggcg atcatcaatt tgccggaaca tgtatcaagc agtgatgtat taaaagcaat
     2701 tgactggaac aacgcctact tgtatattgc cggtgccccc atcaaggtta ctagcggaag
     2761 tttattatca gcaggaagcc ataccttgcg ttttgggatg gggtcgtggg atacaaatac
     2821 tctattgaca gatattattg ctattattac gcgaggcgaa ttcaacgtgg acgatatccc
     2881 gcttcaattt gatgttacag ctaatgtcgc gaagatgaca gaaaacggag ataaatatga
     2941 tacgagtcca aacaaaattt tgaccaaggg taaattacaa ccttctatgt ctaaaaaggc
     3001 cgttttttct gttgattttt atgattcgaa taatattatc caagatcgta tgttcaattc
     3061 gattttagct ccagctgcag gtagatttta tcctaaatta actggcggaa acttgaatcc
     3121 aggagcatat gcattttctg caagtgcaga gataaatacg tggaatagtt acatctcacc
     3181 aagtgattca acaggaaaat ataatacatt tgctgatacc acagaatacg tggatggaaa
     3241 taaccagaac cttccaggct ctaccaatag tcggacattg acgatggggc tgactgaagg
     3301 acgttttgat cagttgccat ttagtcgctt tgatcgcgta gtcaactatt ttacaggaaa
     3361 aaacgttaca caaggagcaa tactgactca tactccagca agcacaagtg gattgaatca
     3421 gacagccaat atcgtgtaca gtgggaaaga tgcgcaaggc ggattgcttt ctcctgttgc
     3481 tttaaaggta ttggagcagt acaagctaga cggaacggtt ttaccaacaa acttaacagc
     3541 cgatagtcag tggggaaagc tcctttcttc tgcatcgtac caagtcacgg ccaattggtc
     3601 agcaactgaa ctaaaaaagg gttcgatcca ttacaggctt tattcgaaag gaacccaaaa
     3661 attagcgaca ggatggacag atcaactttt ccaaacgatc caatcaaata acgggggtgt
     3721 aaatacagct acttctacac tacctgcatt ggcttcaggg caatattatt ttgattatcg
     3781 cttggtggac gatgtactta ctaacatgta tccgtctttt gcgtacaaat ggcagtctga
     3841 acaagctgga atcaccactc ttcctcaaat aacagtggct aattttccat ctgtgagtgc
     3901 agatagtcag ctaaaaaacc ttagcagaca acctgagaca ggagatcccc tgtctgctct
     3961 atcaggagat acgattcaag aaaatgtgac attcacgtta acaaaatctg gggatgcgat
     4021 aaccgacaaa aaaatcacga tctcacttcc tgaaaatact acttatatca atggttcctt
     4081 aaaattaaat ggtacaacta tcgcagatac cggcattcaa caaggagttt ctgtcccagc
     4141 agatctattg agcaaaatag gagataccat tcatcttact tacaactatc aattaaatac
     4201 tgtagatact tctttacaat ccgtcagcat actgacaaag gcagctgtac tttccagcaa
     4261 tattacatta gcagatggtg ctaagcttcc taacccagtt gtccaaacat ctgctaaaac
     4321 aattcttgtc cccaaacaag aattaacatt agttaatgta ccagatgatt ttacatttgg
     4381 taacgatctc cccaaaccgt tgaagacaag ttattatgaa tcaaaaggcg atttttcttt
     4441 tgatgtgcgg gatactcggc ttccaagcac gtctccttgg caactgacag gtacattgac
     4501 ttctttattt aagaatgatc aaggtcaaga attaagcgga acaaaattat acttcaatca
     4561 ttctggatca aagcaattga ttcagcaagg tcaaaacacg ttgatttatg agagtgatgg
     4621 aacagctaaa ggagaggttc tcgttgactt tcccgatacc gatggtttac tcttagaggt
     4681 aaatagcagt acgaatgctc aacctggcgc aacgtatcaa ggcatggtca catgggaact
     4741 gacagctggg ccaaccagct aagtgattag aatttgtatg gatctgtgat aactgtcaca
     4801 gatcctcttt ttcaaggatg agaaggaaac ttctgctgtt aaaatcagaa atgcttgaag
     4861 gagtggactt ggaacttttc agtttgcttg aaaaaaatga acaacggcaa atcaaacttt
     4921 tccaactttt attagaggaa aaaggagagg tttccgttaa taacgtactt acccgcttat
     4981 cagttgatcg ggctaccttg aaagaagatc tgttttattt acaagctaac ttggaaaata
     5041 tcaaacaatt ggaaattgtt atccaagaag ggaatatttt attaatcaga catggaaata
     5101 tagcagcagt cgatgtttat tatcattgtt acttgcgcta ttctacaaaa tatcagatac
     5161 ttctttatct gttggaaaat ggctcatttg atcggcagaa acttgtcatg gaacttaata
     5221 tcagttcggc tactttgtct cgcagagtga aggaattaaa tgattcttta aatgagtttc
     5281 atctgaaaat aaaaagcggg cggctgaccg gtccagaaag tcaaattagt tatttttatt
     5341 tccaattatt ttggtttgga cgtccctatc ttgaaaacaa aaaagaatac agtgatttat
     5401 caggaaacac ttttttagat ctgctgcaaa aagagtttag ttttgctatt acagaagaag
     5461 gacgattgaa atttgaaata tggctttcca ttatgaagaa gcgaatgcgc tgtacgaaaa
     5521 aatccaaacc agattatagc aatcttcctg ttggattgtt tcaaacgaca caatttttat
     5581 tggacctcca tacatttttg acccgttact tctttcaata tgcctttcct tggaatcaaa
     5641 atgaaacgtt ggttttttat cttttcatga tcagtaactt tacattagat acacataact
     5701 cgcatgtcca ggagtttttg ataagcgaaa aatacaaaga cgacgtagta gctcaattga
     5761 atcgaacgtt taaacaatcg atagaagaat atttctcttt ttatgttttt ccagaagaga
     5821 tttcgcaaaa gattgcgttg acagtgatgc aaaatcacgc tcattttgcc tattttagag
     5881 gatggatgaa tatttttggc caagaaggat taaaacagcg gttaactgaa gtagaagata
     5941 aacaattcct ggttttatgt gaaagattgg tcagacaaac atttgctatt gttgatttta
     6001 ctgaagtaga cgaggaaaat gcccgctttg aattatttgc tcgctatgca tctattttac
     6061 ggacgctgat caagcagtta gaattacgtc tgcaaattgc ttatgatctt ccttatgaaa
     6121 ggctaatggc ggatatcgtg aaagaaatca tccaggaaca attgctgaat acgatcaaat
     6181 atgatttagt cgaatacgag aaagaaaagc agtatgatat cattttgact agccaattga
     6241 aagagtaccc gtcacagaag tccgctaaag tttttgtatt cactagcaac gaatataatt
     6301 atgatttccc ctatttgaac caatttttaa aagaatgtta tttagaaaaa ttgaatttaa
     6361 ggatgaataa aacatgaaaa tcgtgatcat tggtgcttcc catgaaggca tcacagctgc
     6421 cctaaatcta agaaaacttc aaccgaaagc agaagtttta ctgatcgatg aagatcataa
     6481 agatggacta ggctatgttt caaatggaat caacctttat ttaaaaggaa agatacgtag
     6541 tttagctgaa gttgcccata acatgcggac tcttcaagaa agtggggcaa aactgatcac
     6601 cgaatggaga gtaactgaac ttgatccaga caaacatcag ctcatcctcg catccaaaga
     6661 aggaaaaaac gagaccataa cctatgataa attaatcgta gcgacaggtt cctctcctgt
     6721 caccttgtat aaacaaattg aagctgaaaa tgtctacacc tataaaaatc tagtgcaatc
     6781 taagcaagta cttgccgctt taaaagaagc aaaagaagta gtgatcttcg gtgctggtta
     6841 cattggattg gaattagcag atgctttgag aaataaagga tacattattc atctagttga
     6901 ttatatgccg aatgttttat caagatattt cgataaggat atgatcaaca gttttcaaaa
     6961 tcagctgcaa actaagcaaa taaattttta tccaaatgaa ttcttgatcg attggaaaaa
     7021 atcagaagag aaagtagtat ccgtacaact tctgtctcaa acaataaagg cagatatggt
     7081 cattttttct gcccaaactc gtcctaatac gacattgtta aaagaaaaag tggctttgta
     7141 tgaggatgag actgtgatag tcaatgaata tctgcagaca agtgatccgg acatctatgc
     7201 gattggagat atcgtcccag tcagttttga caaaaataaa cggcatctct ttttaccttt
     7261 agttactcga gctgtacata tggcaagagc agtagcgcta actttgagtg gtcagccaac
     7321 cgcttacgac ctcagacaaa agataacagc agcagtcatt atagactact ttttaggaac
     7381 tgtagggctg acagaagatg aagcgccatt cttggaacaa aataccggtt cgtgttcagg
     7441 agaatttgat ctatttccac aatacgacga agaaaacaaa acagtaaatg caaagctgat
     7501 ctaccatccg gatacattag aaataattgg cggacagctg ataagccaag aattcttatt
     7561 atcagatttg aacctgcttg cggatatcgt gaaacacaaa actacgattc cacagctagc
     7621 agttgaggat tttggatttc tgtctgaata cacctctcgt tttcactacc tcaatgagtt
     7681 agcttttaaa gtactagcta agagagcaaa tagcaataga gtagataaaa gactgtgaga
     7741 aatatcacgg tcttttattg tgtggggata taataaatat taatcaatcg agaataaaaa
     7801 attcatataa tgaaatagcg gaagaatttt ttgagcataa tattcgccaa aaatttatca
     7861 agtgataaaa ttgttgtata aaatgattat ttcaggagga ggagttaaat gtttttagca
     7921 ttaaatgaaa ttatgcattc aaagttacgt tatgcgttag ttgcaggggt gatgtttttg
     7981 atcgcctacc tggtattttt tttgactggg ttagcttatg gcttagctca agataatcga
     8041 acagcagtcg acaagtggga ggcagattcg attgtgcttt cgaaagatgc aaattcaaat
     8101 ctagggatgt ccatgattac taagaagata gcagaagaag tcgaaggtgg gaaagtggcg
     8161 tatcttgccc aaacacctgg agtcgtgact agtaaagaca gtacagaaga aggaaaaatc
     8221 aatgttagct tcttcggtat cgataaaaat caattcatca tgcccaatct tgttgaagga
     8281 aaagcttttg ataacgatga tgaggcagta ggcgatatta gtttgaaaga agaatatggt
     8341 ctagccatag gagatacagt taagttatct ggtagtgaca agacgtttaa actaactggc
     8401 tttacggatc atgccaaatt caatgtctca ccagttctct atacaaccat caatgcttac
     8461 caagaaatcc gcttcgaaaa agaagataca agtgaaaatg cacggattaa cgcaatagtt
     8521 gtcagaggta aaatcagtaa tttacctgaa gatttagaac agatcaaaat ttctaaattc
     8581 atcaatgaat tacctggata taatgcgcaa gtattgactt ttggatttat gatcggattt
     8641 ttgatcgtta ttgcggctat tgtgatcggg attttcattt atgtactgac gatgcaaaag
     8701 attaatatct ttggtgtaat gaaagcacaa gggatcacag gaggatttat tgcgcgttct
     8761 gtagtggcac aaacattcat tttatcattt gttggtattc ttcttggtct attaggaaca
     8821 gtgggaacat cccttgttct acctgatgcg gttccattcc aaagcaattg gctgtttttt
     8881 ggcgtcatta gcttgttgat gttagtagta gctgtgttag gcgcactatt ttctgttcgg
     8941 acaatcgtaa aaatcgatcc gttgaaggca attggataag aaggaggaag aacatgaaag
     9001 caatagaatt taaagaagta gaaaaaagtt tccaagatgg cgaccaagta gttaaagcat
     9061 tgaaagaaac aaccatgagt atcgataaag gggaatttgt tgcaatcatc ggtccttctg
     9121 gttcaggtaa aagtactttt ttgactttgg caggcggatt gcagacgcct agcagtggct
     9181 ctgtatttat caatgatcaa gaattcagta atcaaaaaga aagcgaacgc gttaaactac
     9241 gttttaaaga aattggcttt attttgcaag cttccaatct ggttcctttt ctgacagtaa
     9301 aaaagcagtt attattagta gataagatta aacatgaaca tcgtcaaaaa gaagcaaacg
     9361 aattatttga gcagcttggc gtggataagt tgatcaacaa gtatccagaa gaactatctg
     9421 gtggagaacg gcaaagggtc gcaatcgctc gtgcattgta caatgatccg tccattattc
     9481 tagcagatga accaactgct agtttggatt cagaaaaggc acgagaagta gtcgatatct
     9541 tggcaaaaga atcaaaagac aaaaataaag caacgatcat ggttactcac gatacacggc
     9601 tgattgacaa atgcgataga atatttatga tggaagatgg tgtattgaaa gaaaaagaat
     9661 aaccaaaaag caggtggaaa aatggtccat cgatacaaca aagatacaca gcaaaaaatt
     9721 ttgaaagaag cgactgactt gtttatgtcc aagggatatc tcggcacttc aacaagagaa
     9781 atcgcacaaa aagttgggat cacccagccc aatctctatc attatttcgg tgataaagaa
     9841 aaactatata cggcagtttt agaaaaccac ttaaaagatg ttggaaaagc tttgagagaa
     9901 atcgttcaaa caagcgaaac gggatttcaa gtaaccttga caaaaatggc gcagtttttg
     9961 attgagacac atctggtcga tttgtttctg atgcttcacg atcttgaaag caatctttca
    10021 aaggaaacaa gagatcatct tttctttcta tggaagaaaa attatcgtga accttttgaa
    10081 gaaatctttt cagcaaacca atctgtgcta agaaatggga tttcaaaaga aatcgcagca
    10141 aggcattttt tcttagtgtt agcaccttac atcactcggt cgaaaagacc tgtggaagaa
    10201 ccgctaaatg tggcgcaatt gatcgattta tatttgaatg gtgtattagg agaagcgtaa
    10261 agctgttata tagggagaaa atagttaggt gaagaagcaa gatatgacga agatcgttat
    10321 atcttgcttc tttatatagg tagtttttca taaatacaaa tttgttattc tctcatgatt
    10381 atcagggtat atttttattt attatgtcgg tgttccagga agtgttttaa tttaataacg
    10441 aagaaattaa ttgtttgtag aatgaaggaa actatttatt gggtagatga atcaccacga
    10501 atagtcaaaa ggagatttca ggatatgcca aaaatgaaaa aaatcatttt agcagtaatg
    10561 ttattttcta cggttatatc ttttacagcc ccttttttgc ttacttaagc tgattttaag
    10621 ttttggccct tagtctggat ctacgaggtg agagtcaaga atgaaaaaaa taattggagc
    10681 ttttgtattt gcaatcatta tcattattat ctgttttcaa atagatgttt ttggtcaaaa
    10741 aaagatagtt ggacaaacgg tcagcagtac gaacagtacg gttacaaaga caaaggaatc
    10801 atttgatgat acagaacaag agacattaat caaaatcgga aaaaatgacc gtacactata
    10861 tacagatgac tcgctaacta ccccacttgc aactataaac ggcggagagc tggcggagtt
    10921 tctttctgaa acaaaaaatg cttatcagat caagacaaat gatggctata ctggatattt
    10981 agccctcgaa gatggaacca aagtcacaaa gaatatacaa acaaaaccgg aagagctatc
    11041 tgatgcagtg attgtattag atcctgggca tggcggaaat gatactgggg cattaagcaa
    11101 tgatgaacaa acagaagaaa aagatataac attaagtaca gccataaaag taaaaaaggc
    11161 gctagaggat gctggagcaa cggtttattt gacccatact acagatgaat tagtacagct
    11221 tggagatata tgcgactaca gtgaagaaaa aaaggcagat gtctttatca gtttacacgc
    11281 agactctacg gaatatgcga atgaagcaac tggaatcacg acatattatt actatggaca
    11341 agaggaaaca ttagcacaga caattgctga ctccttcact gatctgcctc tggattcaag
    11401 aggaatctcc actgggaact atcaagttct tcgagaaaat cttcaacctt ctattttaat
    11461 cgagatgggt tatatgaata atgatagtga tttaaaggaa ttagtaacag acagttatca
    11521 gcagcagatt gctgcaagtt tgacacaagc attgaccact tattttcagt aataaataag
    11581 cccagccaaa caaaaatagc tcctcatatt tttcgtttgg ccgggcttat tatcgcagat
    11641 gcaagctttt aaacaccgtt taaggaagag gtcgtgagcc tgccgttcaa ctctgagtca
    11701 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga ctattgtgac ttgtgaccga
    11761 ggagttggca tgagaacacc gtttaagaaa aaggttgtga aatcaacgtt ttgttctgag
    11821 tattagagaa acaaacggaa aaatagttcc tcatattttg ccgtttgttg agctaatacc
    11881 gaggatcaga tgattgaaca ccgtttattc ggaacaaggg actgtgacat gacttttgtc
    11941 acagttccat tattttttta gtagcttcaa agctttttct gtattggcaa aatgaagttt
    12001 ggcatatttt tcaagcatag gcatgccgcc tttctccaat agttttgccg ctacttggtc
    12061 agatttcgtt ccagctcctg acggaagggt gattccagct tcagctgatg ctttgtctaa
    12121 ctcttccaaa aagctggcac gactgatgat agaagcagca gcaacagcta aatgatattg
    12181 ttctccttta gtaacgaagt acagtttttc ttgtaattga tttttttcta aacgcgcata
    12241 ttttttaaaa tttgcttccg gcgtaaactg atcgatcaaa atcgcttctg gtttttctgg
    12301 ctcgattttt tttagcagca aatggatcgc ttgattgtgc aaagcgactt tcatccgaac
    12361 ggcattgtat tttggttgga tctcattgta tttttctgga gataagacaa gcagtttata
    12421 ggggatggtt ttttttaaga tgtcagcaag ctggatgatt tggctatctt ttaactcttt
    12481 tgaatctcta acaccaagtt tacgtaattc tgcaagctga tcacgtttca cataagcagc
    12541 acatactgtt agcggaccga aatagctgcc atttccgacc tcatcactac ctaaaacgga
    12601 taattgactg atattttttg gcaaagaaga ggctgttttt gctggcttgg cttgtttatc
    12661 ctgtgcctcc ccccatttat cagcttctat tgctgcattc gtaccttgaa acatcacttt
    12721 tccggatgta taagcggtaa tggtcgtccc gtcttttttt gcagcaaagc tagtataagg
    12781 aatctgttta tttaacaaat aagagcgata gtatgctttc atttgactaa gttggtcgtt
    12841 tgttgctttg ataatgacgt tgctcataaa attctcctcg tttttataca taaaactata
    12901 ccgcaactca cgacttttcg ttttctaaga gattgcgaga catagcattt ttttaaagtt
    12961 tatcatataa tagttaagta tgtgaaaaat atttgtggag aacggtgaaa gaaccaactt
    13021 catggtacac taaataaaac tttcatcaaa taggaggaaa tgattcgtat ggcgcacgaa
    13081 aaaacacgct acaaagcggt gattgccaac caaacatata ctattatcgg acgggaaacc
    13141 aagcatcata tggatatcgt aacgaagctg atcaatgaac agttagcaga attgaaacaa
    13201 ttatcaccac aaatggataa tgaacaagca gcaatcttga tggctgtcaa tgcgctttcg
    13261 gatcaattga agaaacaaga aagaatattg gagctggaag aagaaacagc agaattaaag
    13321 aaaaaaatga tcaaatttac agagcttgaa aatcgtgtga aacgcattga agcaatcgag
    13381 aacgaagctc gggaagtatt gaaagaaaat ggtcaagcag atcataccat taaaaatcat
    13441 gtggaagcac aacagatttt aaacgagaaa cgaaaaggac aaattaaaca aaaatcttct
    13501 aattaagatc cttttatcaa aataagaaaa atttaaaaaa gttagaagag aaaggaacgt
    13561 agcatgctga gtttgctgat tttattttta ttgctaattg cgtttttttc tggagcacgt
    13621 cgcgggtttg ctttgcaaat catattcgcg attggatatg tattgtcatt tattgctgcc
    13681 cagcattttt acaaaccatt agcaagtcat ttggaattat acattccata cccagctgtc
    13741 accccaacat caaagttagc attttttgat caggtatttg cctttcacct agatgaagct
    13801 ttttatgcag gaactgcttt tctgattatt ttgctaattg gctggctgct tacccgattt
    13861 gtgggggttt ttgtccatgg attgacgtat gtgccgatct tgagacaggt agactggatt
    13921 gcaggaggca tcctgtcact aatcatggct tacgttacta tatttttgat tttgcagtta
    13981 cttgcctttg ttccattaga tgtggtccaa aatcaattcg gcgagcatag tttcgctcgt
    14041 tttatcgttg agagaacgcc atttcttacc aacaagatgt atgagctttg ggtaacgaat
    14101 attttgaatt aaggaaaata gtgctggaaa atatttcgtt ttttgtacag agtagtttat
    14161 ttaagaaggc tgcgtagcgt atgtccggca cagctctttt ttcatagtga aagataaggt
    14221 gataaaatga ataaccgaat ccttgaaaca ttggaatttg aaaaagtcaa acagatggtc
    14281 agacaatttg tagtgactgc acaaggaaaa gaagaactgg cagaattggt accagtgagt
    14341 gagaaacaaa cgatcacaaa ctggcttcaa gaaactgagg atggattgaa agtgcaacgt
    14401 ctgcgaggcg ggatccctat acctaaaatt gaaaatatcc gtccccatat gaaacggatt
    14461 gagatcggag cagacttgaa tggagtggag cttgcacaag tttccagagt attgtctacg
    14521 acaagcgaat tgaatcgttt cattgatgat ctttctgaca gtgaaatcga atttgcacgt
    14581 ttgtatatgt gggcagatca gttagtcacg atccctgttt tgagccgccg tttaaaggaa
    14641 gcaatcgatg aagacggacg cgtgactgat gacgcttctc ctgagttaaa gagcataaga
    14701 cagaacattc ggcgaagtga acaagctgtt cgtgaacagt tagatgggat cgtccgtggg
    14761 aaaaatgcaa agtatttaag tgatgcgatc atcaccatgc gaaatgaccg ctacgttatc
    14821 ccagtcaaac aagaataccg cggtgtattt ggcggtgtag tccacgatca aagtgcttca
    14881 ggtcagactt tatttattga accaaaacaa gtggtggatt tgaataatcg tttgcgtcaa
    14941 taccaaatcg ctgaacgaaa tgagattcaa cgtattttaa gtgaactttc tgctgaactt
    15001 gttccccatc gtcaagaaat catccacaat acttatgtga ttggtaaaat ggatctgatg
    15061 aatgcaaaag cacgatttgg taaagaagta aaagccatcg tgccgggaat cagtgaagac
    15121 aatcatgtcg tcttgaaaca agcaagacat ccactgatcg atcaggaaaa agtagtttct
    15181 aatgacatca caatcggaaa agactatcaa gccatcgtca ttacaggacc taacacaggt
    15241 gggaaaacga tcacgttgaa gactttaggt ctgttacaac tgatggggca agcaggatta
    15301 ccgattcctg caggtgaaga aagtcaaatc ggtatttttg aggaagtatt tgcggatata
    15361 ggagacgaac agtcgattga gcaaagtcta tcgacctttt cttctcatat gacgaacact
    15421 gtagatattt tatcaaaagt caatgaaaaa agtctggtat tatttgacga gctcggtgca
    15481 ggaacagatc cgcaagaagg tgctgctcta gcaatcgcaa tcttagatga tcttggtaaa
    15541 aagtctgctt atgtgatggc aacaacgcat tatcctgaat tgaaagttta tggatataat
    15601 cgggcaaata cgattaatgc cagcatggag tttgatgtgg atacattaag tccaacgtat
    15661 cgtttgctga ttggcgttcc tggacgaagc aatgcgtttg aaatctctag ccgattaggt
    15721 cttgatacag aagttattga tgaagcgaag cagttgatga atgatgagag ccaagattta
    15781 aacgaaatga tcacagattt agagaatcgc cggaaaatgg cagagaccga atatctggaa
    15841 atgcgtcatt ttgtttctga ggcacaagaa cttcacgatg atttgaaaga agcttacagc
    15901 tatttctttg aagaacgtga aaaagaaatg gaaaaagcaa agaaaaaagc aaatgaagtc
    15961 gtgtcagagg cggaagaaaa agcagaaaaa atcattgctg atattcgtaa aatgcaacag
    16021 cagattgggc aaggaaatgt gaaagagcat cagttgatcg atgcaaagac ccaattagca
    16081 aatctacatc aagaagaaac tttgaagaaa aataaagtat tgaagaaggc gaaagaacaa
    16141 aaaacgttga aaccgggaga cgaagtgttg gttacgactt acggccaaag agggacgctt
    16201 ttacgtaaaa acgggaatca gtggcaagta gaaatcggta tattaaaaat gaatgtgtcc
    16261 gaagacgagc tgacgcctgt tgctcctcaa aaagagccga cacaacgagt tatccatgct
    16321 gtacgatctg aatctagtag tcacgtgccg aatcaattgg accttcgagg aaaacgatac
    16381 gaagaagcgc taagtgaggt agatcaatat ttggattctg ccattctagc tggttatcct
    16441 caagtgacta ttgtccacgg aaaaggaaca ggcgcacttc gcaagggaat tactgattat
    16501 cttaaaaacc atcggagcgt caaaagcttt gagtttgcac cggcaaacca aggcggaaat
    16561 ggtgcgacaa ttgttaaatt taagtaaagc ttactaaagg taagcagatg gttcgctatc
    16621 caagtataga aatgctatac tagtcataga ttttaaaaat ggaggtcttt gatatgtcac
    16681 aagtaattac agataagaca tttaatgaag aaacagataa aggacttgta ttgattgatt
    16741 tttgggcaac ttggtgtggt ccatgtcgta tgcaagcacc gattttggat cagttggaac
    16801 aagaatatga tgaagaagaa ttcagaattg ctaaaatgga tgtggatgaa aatccagaaa
    16861 ctcctcaaca attcggtatc atgagcattc caacattaat gttgaaaaaa gatggtcaag
    16921 tagtagaaaa agctgttggt gttcattcaa aagaacaact acgtcaaatg atcgatcaat
    16981 atttataaaa acttacagca aaaataagct gagggtggga ctgaatccag ttccgtcctc
    17041 ggtttttttg cggttgagtt aaggttattc aaattaatat tttttgagta taattacgtt
    17101 gtcaggctgg attgtttttt tgacagacat gctataataa ctttaattga atatgaaggg
    17161 gagtaccaga tgaacgaacg aatcaaaaac aaattagctt tacttcctga tcagcccggc
    17221 tgttacttga tgaaagataa aaatggaacg atcatttatg tcggcaaagc caaaatatta
    17281 aaaaatcgtg tccgctcata ttttactggt agccataata cgaaaacgga acggcttgtt
    17341 agtgaaatcg aagactttga atacatcgtt acagaatcga atatcgaagc attgctctta
    17401 gagatcaatc tgataaagaa aaatgatcct aaatacaaca ttatgttaaa ggatgataaa
    17461 acctatcctt tccttaagat aacgaatgaa aaatatcccc gtttggtgat tactcgtaag
    17521 gtactaaaag acaaagcact gtattttgga ccatatcccg atgtcggtgc ggcgaatgag
    17581 acaaagaaga tcctcgatcg attatttcct ctgagaaaat gcaaacctag tcagacgaag
    17641 gagccttgtc tttactatca tttgggacaa tgcctgtgtc cttattattt cgacgtagat
    17701 ccgaaagtct atacgaaaat cgttgatgaa gtgaaaaact ttttaaacgg aggacacgaa
    17761 aaaatcgagt cagagatcca tcagaaaatg gaaaaagctg ctgaaaacat ggagtttgaa
    17821 aaagctgcag aataccgaga ccagatccgt gccattgaga caatcatgac ttgccaaaaa
    17881 atgacaaata ctgatttact ggatcgagat gtatttggtt atgcgattga taaaggatgg
    17941 atgtgtgtcc aagtgttttt cgtaagacaa ggaaagctaa ttgaacgaga tgtttcaatg
    18001 tttcctttct ataacgaagc agaagaagat ttcttgactt acctcggtca gttttatcag
    18061 gaaaatgagc atttcattcc taaagaagtc ttgattcctg atacgatcga caagcccagt
    18121 gtagaagctt tgttagctac gaaagtgctg caaccaaaac gaggagaaaa gaaaaaatta
    18181 gttgaattgg cgagtaagaa tgcctcagtt gctttgaatg aacggtttga tctgattgcc
    18241 agaaaacagg aacggacgat cggagcagtt gaacgtttag gaaacgcgat gaatatcccg
    18301 accccaatac gtatcgagtc ttttgataac tctaatatca tggggacgaa tcctgtggct
    18361 gcgatggtcg tattcattga tggaaaaccg gcaagaaaag aatatcggaa atataaaata
    18421 aaaacagtca acggaccgga tgattatgca tcaatgagag aagtcatcta tcgcagatat
    18481 tcgcgagtga ttcgcgaagg gttgccttta cctgatttga tcttgatcga tggaggaaaa
    18541 ggacaagtag atgtggcaaa agatgtctta gaaaatcaat taggaatcga tattcctatt
    18601 gctggcatgg taaaaaacga taaacataaa acaaatgagt tgctattcgg tacagatttg
    18661 gctgtagtac cgcttgagcg aaattcacca gagtttttct tactccagcg aatccaagat
    18721 gaagtccatc gattcgcaat cactttccat cggcagctac gcagtaaaaa cagttttgct
    18781 tcccgattag atgaaattga agggttagga ccaaaacgaa aaaaaatgct gcttaaagag
    18841 ttcaaatcgt tgaaaaatat cacagcagcc acgacagaag aattacaaga aatcggactg
    18901 ccgaaaaatg tcgcacaaaa cgtatttgat aaattacatc aggaatgagg aaagggcact
    18961 ttacaaagaa agtaaagtgt cctatcattt tatgtacaac aaaaagagcg tttacgtttt
    19021 gttggtaaat aataaatcgc ttacgtctgg tgtctaagga tatatgtgat ttcttgaaga
    19081 aggagtgaag aaatgttaga agtcaaggat cttgttaaaa cttttgggaa ctacacagct
    19141 gtcgatcatg tctctttcca aatccccgat ggaaaaatca tggggctaat tggccaaaac
    19201 ggggctggga agacaacgac ttttcgtttg atcttggatt ttttgacaca agaccaagga
    19261 gaagtgttat ggaatggcca tcatcttggg gagaaagatt atgatgtcat cggttatctt
    19321 ccggaggaac ggggacttta tccgaaagta acgattcaag accaactgct ttattttgca
    19381 gaacttagag ggaaatcaag aaaagagatt gaaccaaaaa tcgacttttg gatggaaaaa
    19441 tttcaggtaa aagggaaaaa gacggataaa gtaaaatctt tgtctaaagg aaatcagcaa
    19501 aaagtccagc tgatcgccac gttaatccat gaacctaaat tgatcatttt ggatgagcca
    19561 ttcagcgggt tagatccggt aaatgctgaa ttgctaaaag atggaatatt ggaattgaaa
    19621 aaacatggtt catgtgtcat tttttctagc cacaatatgg ataatgtaga aaaaatctgc
    19681 gatcatttga tcatgttgcg aaacggaaaa atggttttga atggaaaagt acatgagatt
    19741 cgtgaatcat ttggccgtac gaagttattc ttggaatctg gtttaagcca acaggaagta
    19801 gaagaaatcg aaggcgtgaa aaaagtgatc cttcatgaag acaatacgtt agagattacc
    19861 ttagaagatc ctgaagctgg gaaagaaatc tttactcgtg cgactcagtt cggctacatt
    19921 cctatgttta accagcaacc gccaactttg gaagagattt tcaaattgaa agcaggtgaa
    19981 atcgatgcgt aagttttgga ttattaccaa agatgtctat ttaaaaaatg ttaagtcgat
    20041 ttctttcttg atcatgatat tagtcccttt tatcatgctg ggtatcattt atgtagcagg
    20101 aaactttgct caacaaaata gtgatgtcaa taaaatcggc gtattggctg ataatgagca
    20161 aatcagtcag caaatgagcc aagtcaaaac agatgatttt gagttcaaag cagttgattc
    20221 tgaagaaaaa gcacaaaaag agctttcgga agaaaaaatc gatgcgtatt tagtagtctc
    20281 aactgagaat gataagataa atgggatgct ttatagcgaa aattcattag gacaaagtac
    20341 acaactactg atacaacaac aactgactgg cttgcaatcg atgcttcgag cgagtcaatt
    20401 aggcatttca ccagaagaag tagctagctt gagccaacaa gcaagtttga ctcgacaaaa
    20461 agtcaatttt gattcaaaag gaaaaatgac agtcggagaa gataactcga cagtccaata
    20521 cgtcgtaagt tatgtagcaa cgattgtctt gttcattatt attttgacgt atgcgcagat
    20581 cattgcacaa gagatcgctt ctgaaaaagg cacgcggatc atggaagtga tcctgtccag
    20641 tacgactgca caaaagcatt tttacggaaa attaacaggt gttttacttg ttgcattaac
    20701 gcaaatggca ttatacggta ttatttttgg tataggatac agtcaattca aagatatgga
    20761 aatggtcaaa aatatattag acggtatctc attggataac ttgattggac cattcttgtg
    20821 gtattctctt ctattcatga tctttggcat tttgattttt tctgttttag cagctttatg
    20881 tggctctttg gtcaacaaag cagaagatac agcaaaagca attttgccag tgacttatct
    20941 atctctaggc ggatacatgc ttggattgat actaggagct tcagatccaa acaatatcgt
    21001 tattcggatc acttcgtata ttccattctt atcttcatat attatgccga ttcgcttagc
    21061 aaatgagaca gtcggtatgg gtggagcatt gatttccttg ttggtacttg tagccgtaac
    21121 attcttattg atgatcttgt ctgcaaacat gtacaaatcg aatgtactcg tttatagcga
    21181 aggcggatta tggagttcat tgaaacaatc gatttcaatt atgaggaatg aacgaaaaaa
    21241 agcataaaac aatcctaaaa tacagaagga agctggacat ctattgttcc cagcttcttt
    21301 ttgtatagac ctattttatt tattttacta tattggatat atattcattg aaaatagtgt
    21361 ataacaactt tataatattg agtataccaa tttttggagg cgttttaatg gaccgttatt
    21421 tagatttact ttcagaaaaa ttcccctcaa cggaggatgt catcacggaa atcatcaatc
    21481 tcgaagcaat tttgcagctt ccaaaaggaa cagagttatt tttgagtgat atacatggcg
    21541 aatttcctgc ttttgatcat attctgcgta tcggttcagg aaatcttaaa gaaaagatca
    21601 aagacctttt ttctgaacaa atgacggaaa cggatatcag ccaattcact atttttacgg
    21661 cttatccaga atatgcatta acgactgatt ggtacaaaga acaagataaa tcgcagctga
    21721 tccatcattt gatcgatctt ttacggttta cgacagtcaa atatacccgg tcaaaagttc
    21781 gaaaaggatt gccgaaagaa tatagctata tcattgagga actcttgtat atcgatgacc
    21841 gtatcaatgg aaaaaaagac tatgtaaaaa aaatcattga acaacttgtt ttgatgaagg
    21901 aagaagaaaa atttttaacg aaacttgcac agacgatcca aaaatctgtc atcgatcatt
    21961 tgcatatcgt tggagatatt tttgaccgag gaactcaagc agccaaagtg atggatcgaa
    22021 tcatggattt ttcttctgta gatatccaat ggggaaatca tgatattttg tggattggtg
    22081 cgtattgcgg ctctgaggca tgtttactga cacttttacg gattgcagca cgctataatt
    22141 atttatttga attagagaaa gaatatgggt tgaatttacg tccattgttt tcttttgctc
    22201 atcaaactta tcagaagaat ccagtatttg cgcctaaaaa cagtaaaaat ctatccgaaa
    22261 gagagcaaga agaattagaa aaaatccatc aggcactttc tatccttcaa ttcaaatcag
    22321 aacatcagtt attggatcgt cgacctgaat ttaaaatgga cgatcgtaaa ttgctggaaa
    22381 aaatcgacta tgaagcatca acgattgatt tagaaggtca gctctatgag ttgaaaggaa
    22441 cttgttttca aacgatccag ccagatgatc caaaaaaatt cttggaagag gaacaaaaag
    22501 tgattgatag tttgatgtat tcattccagc actctttgag aatgcaaaaa catatgacgt
    22561 ttttgatcga aaaaggggga atgtatctca cgaacaatca gcatgtgctg tttcatggct
    22621 gtatacctgt agacgagaag ggacagctct tagcatttga attagaccaa tcttatcgcg
    22681 gaaaagaact gctgggcttt tttgaaaaac agataactga aagcgcaaaa gatctgactg
    22741 caaaagaaga tttagcaacc gatttgattt ggtatgcgtg gagtgggcca ttttcgcctt
    22801 tattcggcaa gagtaaaatg gcgacttttg aacgttattt tctcacagag cctcatacgc
    22861 acgtcgagaa aagcaatcct tattatcact tgcgagatga agagtggttc agtgaaaaaa
    22921 ttttagcaga attcgacaca aaagaagaag ggtcagcaat cattaatggg cacacgccag
    22981 taaaagtaaa aaaaggggag tcaccgatca aagcaaatgg aaaagtattt gtcattgacg
    23041 gaggtttatc caaagcttat caaaaaacga caggaattgc cggttattca ctattatgca
    23101 attcttatgg tttccaaatc gtgacacatt atccgttttt gcctattgaa caacaatttg
    23161 caaaaaaatc cgaccaaaca aatgtgaaaa aagtaatcga acagcaacta ccacgcaaac
    23221 tcaatcgtga tacaacaaaa ggtatggaac tgcagcagca gattacccag ctcaaaaggc
    23281 tgttggacta tcgaaaggac gattgagaag aattccagtg aacattgttc catagactgg
    23341 agactgagac aaaagtcgtg tcgcagtctc tttttccgga taaacggtgt tcttctgcca
    23401 actcctcggt cacaagtcac actattcaac aaacatgaaa agctgttttt tgaaattgct
    23461 ccttgtgact cagagttgaa cggcaggctc acgacctctt ggtataaacg gtgttcaaaa
    23521 gccagtttct cggtattaag ccaaatttat gcaaaaatgt gaaaagccat tttcacaaaa
    23581 tttttcttaa tactcgaaac taaacagctt tttcacaacc ccctcagaaa gtctattaaa
    23641 attcattcac aaagaaatcg aataagcgct gttcagatgg atgtacacgg tgggtaagtt
    23701 ccggatgcca ttgaacaccg aggattttat gcatatcatc tttgctttga accgcttcaa
    23761 cgagtccatc gttagaaaaa gcgatggctt ttaataaagg tgaaagatct ttgactgcct
    23821 gatgatggta agaattcaca aaatatggat cggggagaag gttgcttaac aaactgtctg
    23881 aaacaatctt gacttcgtga gtcgtaaatt gcggggcagt gggctgttgt tcatgtttta
    23941 ctgaccactt tggatataat gaaagatctt gataaagtgt accttccaaa acgacattca
    24001 atagttggag tccccggcag actgcaaaaa ttggttttct ttgtttcaat gcttccaaga
    24061 tcagtgcctg ttcaaattgg tctcgttgaa tatttgtttc cgttagcttt ggatgaggat
    24121 cttccatgta aagttgtgga ctgacatctt gaccacctgc aagaataagt ttgtcgattt
    24181 gtccaatcag ttgaggagct gaatctggag acatgactgg cagaataaga ggcaatcctt
    24241 gagcatctaa aactgcatcc acgaatcctt gcggtgtata gctcacttga tttccttgga
    24301 aagtatctgt tgctcgaatc agttgatttc cggcaatgcc gatgattggt ttcatttgta
    24361 ttccccctaa agtagactta ttgtaacaag gatttaaaaa aaattaaact atgtaagact
    24421 tgcccctata cttatctgtt cttgctgtgt tactatctgt aaagagaaat ttcgtgtgaa
    24481 attcatgacg atagttgaaa atattgctta atttgttata ataaaaagta agcagaaata
    24541 aaaaggttgg gcgtaagctt caaggatcta gttcttcaag gggtgagaag gacattttat
    24601 tgaaggggcc tgcctatact aagttatctt tagaggtaca tactttcaat gaaaaaagaa
    24661 agcatgtacc tcttttttaa atcgaaagga agtgaagcaa gtgttagaag ctttggaaca
    24721 aatccgaaaa gcagaagaag aaaatgaaaa gcgtgctcaa acactgcggc agcagctgaa
    24781 gatctatgca acagaaaaag agcaggaatt ggaaacgatc caaacaaact atcgacaaca
    24841 actaaaacag ttggtggaag aaaaagaaca atttgaaata caagaattag aaaaagaaaa
    24901 aatgaaattg aaagcagaag cagacaaggt gcaagcaact ttgaaagatc aatatcaaaa
    24961 gcatcagagt caagcgatcg gtgcgatcat tgaaagggtg aaagaaactt atggccgtca
    25021 ctaagatgga aaaagtgacc ctcatttcag ataaaagaaa tcaggagagg attttacaag
    25081 cagtacaagg aatccaaaac gttgaaatcc gggatctgta tcaaaataga acaaacaacc
    25141 agtgggtgga gaagtatttt ccagatacca cgattattga taaagaagca aaattaagcg
    25201 ctttaggtaa tcggttgaaa gacatccaag aagctatcca attcatacaa caccacggcg
    25261 atagccgtca aaagaaactc catttgaaac gtcaagaact ttccttacaa gatttggaag
    25321 ccaattattc cgaagaaaat ttcataaata aattgaaaga agtccttgat ttaaaagaaa
    25381 agtgggaaca actaactgaa gaacgtgatc gtttagaaga agaggaagaa tggcttcttc
    25441 attggcaaca gctggatatt gctccaagta tgtatgcaag taagacgacc atttttgaga
    25501 tggggactgt gagtgcagca aattttgaaa gtttcaagga agaactgagt aagcttgatg
    25561 acgtttatat ggaagaaata gattatacgc caaaacaagt ttatctttcg tatgttgctt
    25621 taaaaaaatc agttgctgtt atagaagaaa ttgctgggaa atacgggttc aataaagaaa
    25681 cgtatcctta tgaacaaaat cctaaagaaa aactgcaaga gaccaagcag caattatcca
    25741 ttgttcacga gcagcaaaag aagataacga cagcgttagg tcagtgcagt ggctatatcc
    25801 aagaatttga atgggtagaa gaagtcacac ttgccgttgc agaacgagaa aaaataaaag
    25861 aacggtttat ccatgcgact tatctgatcg ttttgcaagg ttgggtagat gcagaagaaa
    25921 aacagaattt gctgcatgtg ttaaacgaaa ccgtatcaga agaagatata tacgtcagtt
    25981 tcgaaacacc aaactcagaa gagattcagc aggaagtccc tactaaattg aaaaaccatc
    26041 cgcttgtcga accttttgaa ttgctgactg aaatgtacag tctgccaaaa tatgaagaag
    26101 tagatccaac accttggatg acaccatttt atcttgtctt cttcgggatg atggtcgcag
    26161 atgttggtta tggtttgctg atgctcattg ggacaatact agctcaaaaa ctacttgttc
    26221 taccacgcgg gatgaaacgt ttcgtaaaat tctttgagat tctctcgata ccatcgatca
    26281 tctggggatt gatctacagt tcatttttcg gacagtcatt accaaaagaa ctgtttggca
    26341 tccgcttgcc tttcccaatc ctatctacga cggatgacgt caatacgatt ttgattttat
    26401 ccgtgatttt cggtctgata cagattttgg ttggattatt tgtggcagca aaggaaaata
    26461 tcaggagaaa agattacttg agtgctgtca gtgatggatt tgcctggcaa gggatcctaa
    26521 ttgggatcgt tattgcgttg gttggtgcca tgttgataaa aaatacagca tttgtttacc
    26581 ttggcgctgg gctatcgatc attgctgcct tatgtatctt gatcgttccg attatccaaa
    26641 cgccgtctaa agtcaaaggt gctgccaaag gtgcgtataa tctttacgga ctgaccggct
    26701 atatcggtga tttagtcagt tatacacgtt tgatggcatt gggtatttca ggcggaagta
    26761 ttggagcggc attcaatatg ctagttgctt tcatgccgcc agctgctcga ttcagtgtag
    26821 ggatcctttt gatcatcgct ttacacgcac tgaatatgtt tttgacactg ctaagtgcct
    26881 atgtccatgg cgcacgattg cagtatgtcg aattttttgg gaagttttat acaggaggcg
    26941 gacgtgcctt tgatccgctg aaaacggcgg aaaaatacgt caacatcaat cacaagaaaa
    27001 aaaacaataa ataattggag gatttttata taatgatgga ttacttaatt agtcaaaatg
    27061 gtggaatggt atttgcggta ttagcgatgg caacagcgac gattttttca gggatcggtt
    27121 cagctaaagg tgttggaatg acaggtgagg cagcagcagc attgacaaca agtcaacccg
    27181 aaaaattcgg gcaggctctg attctgcaat tgcttccagg cacgcaaggt ttgtatggat
    27241 tcgttattgc ctttttgatt tttatcaact taggaaatga catgtcagtt gtacaaggac
    27301 tgaactttct aggtgcttct ctgccgattg cttttacagg cttgttttca ggtattgccc
    27361 aaggaaaagt cgcagcggca ggtattcaaa ttttagcgaa aaaacctgaa catgctacaa
    27421 aaggaatcat ttttgctgcg atggttgaaa catacgcgat tttaggtttc gttatttcct
    27481 tcctattagt gttgaatgcc taagcataaa ggaggaaaag cagatgaacg ccattgaaaa
    27541 aatcatctct cagatgaacg aagcagcaga gcaggaaaga gcggcgttag aacaagaaga
    27601 gcgaatgaag atcgatcaaa actttgaaca aaaacgtacg caagttgaaa cagaacatca
    27661 aaaacaaaaa gaaaaacaaa tcgaattact cgaaaaaaaa taccgtcagc taaggaatcg
    27721 ccagcaagta gaagtacgac aagaaaattt gaatgcgaag caggaatttt taagacgatt
    27781 gtttgcagat gcggtaactg aaatggaaaa ttgggatgaa tctgaacaaa tccagtttat
    27841 caaaaatgca ttgtattcat tacctttgac aggaaaagta gcattcattg ctggagaaaa
    27901 atcagcagcc tatctttctc agacgttgtt ggatgaatgg aacaatgaac ttccctttat
    27961 gatggtttta agtgatgaaa ctgttgctga tcaagcgggt tttctgataa acgatcaagg
    28021 agttcagtat aattttcttt tcagcagcct tgtacaagat atccaaggaa cgatgagttt
    28081 tgagattgcc aatcaattat tcgaataagg agggatcagt gtatggaata ccacgaacta
    28141 aatcccttga ttcgcggaag agagcttgaa cttttgtcca atgagacatt tgaacggatg
    28201 attcaaacaa attctgtcga agcacttggt gaaatattga aatccacgat ttacagtcca
    28261 tatatttatg acggatatga atatgacttc gaacagaatc ttttaaagga gcagagccgt
    28321 ctatttcgct ggttaaagga atcagcaccg gagcctgaaa tcgtttggat ctatacgatg
    28381 cgttatactt tccataatct gaaggttttg acaaaagctg agatgacaaa tcaaaatctg
    28441 gaccatttgt atatcgacga tggattttat tcattagaaa ccttgaagga tgccattcat
    28501 acgcaagttt caaatgaact tcctgaaagc attatggaca gtatacgaga agtacgtgat
    28561 tattttgaag agtctaccat tcttcaggga attgacgtga tttatgatcg acagtttttg
    28621 acagagcagc gacggcttgc cgataagcta ggatatcaag aattgctgac agaagtcatt
    28681 gcttttattg acttgaccaa tatcacaacg atggctcgag gaatattgca gaaaagaaca
    28741 tatgggttca tgacgacggt actttccagc tcgggaagta tcgaaaaaga agtatttttg
    28801 aactttgtag ataaagatat ggaagattac acgaattttc tattagagac agattatgct
    28861 gattttctgc gccctgtcat ccgtgaggga aatattgatc tcgtaaagct tgaacagttg
    28921 aaagatgatt atctaagttc attgtatcaa gaagcacaaa cccaggcttt cggaccactg
    28981 ccactactag cctttttgaa cgcaaaagag gtagaaagca aaaaccttcg tttactggtt
    29041 atcggcaaaa gaagccattt cgaatcagaa acaatcagaa agcgggtgag acaagtctat
    29101 gacgcataag atcggtgtag ttggcgacaa agattctgtt ttgccattca aattgtttgg
    29161 ctttgatgtt cgttatggta caaccaagca aaccgttcgt caggcaattg aagaaatggc
    29221 aaagaatgag tatggcgtga tttatgtcac agagcaatgt gcagcattga gcccagaaac
    29281 gatcgaacgt tacaaggaac aaatgatacc tgctatcgta ttgattccca atcatcaagg
    29341 atcattaggg atagggctgg aagaaattca aaaaaacgta gaaaaagcag taggtcaaaa
    29401 tatcttatag tatgaaaagg agatagaaat tttgcaaatt ggaaaaatca taaaagtctc
    29461 cggacctctt gtaatggctg agaacatgtc tgatgccagt atccaagaca tgtgtctagt
    29521 gggagatcta ggagttatcg gagaaattat cgagatgcgt ggcgatgtgg cgtctattca
    29581 agtatatgaa gagacttctg gaattggtcc aggcgaaccg gttcgctcta ctggtgaagc
    29641 tttatctgtt gaattaggac cagggatcat ttcacaaatg tttgacggaa tccaacggcc
    29701 attagatacc tttatggaaa tcacacaaag taatttctta gggcgcggag ttcaattgcc
    29761 cgcattggac catgagaaaa aatggtggtt cgaaccaaca gtagaagccg gagaaacggt
    29821 gagtgctgga gatgttatcg ggatcgtaga agaaacaaaa gttataaaac ataaaatcat
    29881 ggtgccaaat gggataaaag gaacgatcaa aacaatcgaa aaaggttcat tcactattga
    29941 tgaaacagta tgtgtcattg aaaccgaaaa tggtgacaaa aatttgacga tgcttcaaaa
    30001 atggccagta agacgtagtc ggccaatcaa agaaaaatta aacccggatg cacccatgat
    30061 cactggacag cgagtgattg atacattctt cccagtgaca aaaggaggag cagcagctgt
    30121 acctggtcct tttggtgcag ggaaaacagt cgttcagcat caaattgcaa aatgggccga
    30181 tgtggacatg gttgtctatg tgggatgtgg cgagcgtgga aatgagatga cggatgtttt
    30241 aaatgaattc cctgaattga ttgaccctaa tacaggagaa tcgttgatgg aacgtacggt
    30301 attgattgct aatacatcaa acatgccagt agcagctcga gaagcttcta tctatacggg
    30361 aatcacaatt gcggaatatt tccgtgacat gggttatgac gttgctatca tggcagactc
    30421 cacttcacga tgggcagaag cacttcgtga gatgagcgga cgtttggaag aaatgcctgg
    30481 tgatgaaggt tatccagctt atcttggttc acggcttgcg gaatactatg aacgatctgg
    30541 aagagtcatt gcattaggat cagaaggtcg cgaaggaagt ataaccgcaa tcagtgctgt
    30601 atccccgtct ggaggggata tttcggaacc agtcacacaa aatacattgc gggtcgtaaa
    30661 agtattctgg ggtcttgatt ccagtttagc ccaaaaaaga cattttcctt cgatcgattg
    30721 gatacaaagc tattctcttt attcaacaga agtagggaag tatatggatc atatccttca
    30781 agctgactgg gcatccatgg tcaccgaggg catgcgtatt ttgcaggaag aacagcagct
    30841 gaatgaaatc gtgcgtttgg tagggattga ttccctttca gataatgacc gtctgacatt
    30901 agaagtggca aaatccattc gtgaagatta tttgcagcaa aatgcttttg atgatgtcga
    30961 tacattcact tcaagagaga aacaattcaa aatgttgaag atgatcttga cctttggtga
    31021 agaaggacgc cgtgcgttgt cgttaggtgc ttatttaagt gagatcatgg acggtaccgt
    31081 atcgattcgt gaaaggatcg gacgaagcaa atatatcccg gaaacagaat tagaaaaact
    31141 agatcaaatt attggtgaaa tcaagcaaac gatgcaaacg atcgtttcag aaggaggcat
    31201 gagcaatgat taaagaatat cgtacgatcg gtgaagtcgt cggtccattg atggcggttg
    31261 aaaaagttgc tggtgtcaaa tatgaagaat taatcgaagt ccgtatgcaa aatggcgaga
    31321 ttcgtcgtgg acaagtattg gaagtccaag aagataaagc aatggtccaa atattcgaag
    31381 gaacaagtgg tatcaattta cgtgactctt ctgtacgatt tttaggccat cctttagaac
    31441 taggtgtatc ggaagacatg atcggtcgag tattcgatgg tttgggacga ccgaaagata
    31501 acggaccaga gatcctgcct gaaaagcatt tggatattaa cggagaagta atcaatccag
    31561 tagctcggga ttatccagat gagtttatcc aaacaggtat ctctgcaatc gatcatttga
    31621 atacattagt tcgtgggcaa aaattaccag tattttctgg ctctggtctt cctcataaag
    31681 aattagctgc tcagatcgcg cgacaagcaa cggtactcga ttcatcagat gatttcgccg
    31741 tagtctttgc tgctattgga atcacttttg aagaagctga atttttcatg gaagattttc
    31801 gtcaaacggg cgcaatcgac cgttctgtca tgtttatgaa tttagcaaac gaccctgcaa
    31861 tcgaacgtat cgctactcct cgtatggctt tgactgctgc agaatatctt gcttatgaaa
    31921 agggaatgca tgttttggtt atcatgacag acatgaccaa ctatgcagag gcattgcgag
    31981 agatttctgc agcacggcga gaagttccag gaagaagagg atatcctggg tatctttaca
    32041 cgaacttagc tactttattc gaacgagcag gaagaatccg cggactaaaa ggatcggtta
    32101 ctcaaattcc gattctaaca atgccagaag acgataaaac tcatccaatc cctgacttga
    32161 ctggttatat tacagaagga cagatcatct tgactagaga gctttacaag agtgggattc
    32221 agccaccaat tgatgtactc ccgtctcttt cgcggttaaa agataaggga actggacccg
    32281 gaaagacaag agaagaccat gcagctacga tgaatcagct ttttgcagcc tatgcacaag
    32341 gaaaacaggc aaaagaatta gccgtagttt taggtgaatc tgctttatct gatgtagaca
    32401 agatctatgc gaagtttgct gagcggtttg aaaaagaata tgtcaatcaa ggattctaca
    32461 cgaaccgttc gattactgaa acacttgatc tagggtggga actgctatcg atgttgccaa
    32521 gaaccgaatt aaaacgaatc aaagacgaca tgctggacaa atatctgcca gaagggaagt
    32581 gagttctgat ggcacgattg aatgtgaatc cgacccgcat ggaattgact cgattgaaaa
    32641 aacagttgac aactgccaca agagggcata aattattaaa agataagcaa gatgaactga
    32701 tgcgtcaatt catcctgttg attcgaaaga acaaccagct gcgtcaagaa atggaagagt
    32761 ctatgacaga agcaatgtct gattttgtat tggcaaatgc ttcgatcacg gaacctttca
    32821 tcgaagaatt atttgttttg ccggcggaaa acgttgattt gtctatcgta gacaaaaata
    32881 tcatgagtgt aaaagtacct gtgatgaatt ttgaatatga tgaacagctg acagacacac
    32941 ctttggaata cgggtatttg aattccagtg ccgaactgga tcggtcaatc gatcggttta
    33001 ctaccctgct tccaaaactt ttggaactga cagaaatcga aaaaacttgt caactgatgg
    33061 cgagtgaaat cgaaaagaca cgtcggcgag tcaatgcatt agaatatatg acgatccctc
    33121 aattagaaga aacgatctat tatattcgta tgaagctgga agaaaacgag cgcgcagaag
    33181 taacaaggtt gatcaaagta aaaaatatgg gtaccactga ctaagtggta tcttttttta
    33241 aaagaggaaa acgatgatta aacaaagcaa acaaataaag aaacgtttgc cggctgttca
    33301 gcttctcgca ttaggatttt ttctcctgat tttagttggc ggcggcctac ttaccctacc
    33361 attttttagt aatagtgggc atgggacaaa ttttatcgat gcgcttttca ctgcaacttc
    33421 tgctgtctgt gtaacgggat tgacaacatt gaatacagca gagcattgga acagtgctgg
    33481 tcaatttttg atcatgcttt tgattgagat cggcggtctt ggttttatga tggttccgat
    33541 tctatgcttt gcattgataa agaagaaagt cagtctcagc acacgtatta tattaaaaga
    33601 agcgctgaat ctagaagaag tatcaggtgt gatgaagctc atgctttaca tcctaaaatt
    33661 ggcctttgtg atccaattga ttggtacggt tgctttatct tttgtatttg tgcctgaatt
    33721 tggctggttg aaaggtatct ggtacagttt gttccatgca atctctagtt tttgtaatgc
    33781 agggtttgat ttgttaggag acagtttagc caatcaccag caaaatgttt atttgatcat
    33841 ggtggtatct gctttgatca tttctggtgg gttaggcttc atcgtatggc gtgatttact
    33901 ggaatatcat cagaaaaaga agatgacgat tcattcaaaa atcgcattaa ccgttacagg
    33961 taccctttta ttaggcggat tcgttgtgtt ctttttcaca gagcgcaatg gggcaacgct
    34021 agtggaaggg aatatgtttc aacgattggc aaacaccttt tttatgagtg tgacacctag
    34081 aacggctgga tattattcag ttgattacct ccatatgagc catgcaggtc tgattttaac
    34141 gatgtttttg atgtacatcg gcggaacatc tgggtcgacg gccggcggat tgaaaacaac
    34201 tacgttaggt gtgttgctga tccagatgcg ttcgatgttg aaaggacgta cgagagcgga
    34261 agcatttggc cgtaccatcc gacaaggcgc agtgttgcgg gcacttactt tattttttgt
    34321 tacgttgacg ttgtgtgtag tcgccatcat gattttatcg gtgactgaaa cgatacctaa
    34381 aacttctggc atcgaatata ttgcttttga ggtcttctct gcgtttggta cagtaggtct
    34441 tacgatggga ttgacgccag acttgactgc aatagggaaa ttgatcatta tagcgcttat
    34501 gtacattgga cgagttggtg tattgactgt ggtcttctct ctgatgacaa aagcacaaag
    34561 aacacaatca aaatacaaat atccagaaga aagtgtcatg attggataat ttcatcttct
    34621 gacagaaacc tagtgattta gtaaaataag aaaataaaat aatttttctt gcttcttgga
    34681 tactttaagt gcaaaatgtt cgtttatttt ttgaggcact acccgttgtt gaacctcggg
    34741 tagtgcctct tttttattga aaggaatcaa taagatttga ttcctttatt tatcaatagg
    34801 ttataattca tattttttta ttttttcttt tacgatactt agtccagaag ctaaaatttc
    34861 aaggttatta gaggataggg aaattcgaac gaatgcatct ggttgcgcac gtgtagtaaa
    34921 gcgtctggaa tgataaagtc ggataccgtt agcaagaaag tcattctcaa ttatcttagg
    34981 gtcaatctca ggatcaactg gaagaattcg atagtaaggg acacgattcg ttggtttttc
    35041 tactttgaaa agagaatcaa aaagctgatt ggctcttttt gtaagactta atttagtttc
    35101 taagatccta tttgcttcat ttgaatggag gatttgagtg atgacttcca catctaatcc
    35161 agaagttttc acatttatat taaaaattgc ttgttctatc ttgctttgga catgtactgg
    35221 aactacaaga taagcaactc gcaatccaga acaaataaat tttgtcattc cagctaagta
    35281 gattgtttgg ttaggtaata aattttggaa aggaggaatg atcgtatgtt gatagtaagt
    35341 tgttaaaaat gaatggatat catcttcaat aacccataga ccttcttttt caatcacttc
    35401 ggctaattgc tctcgtcttt tgtgagagat ttgaaaccct ataggattat tacaagaagg
    35461 cataagaaag acaccatgaa tcttcttttt tctacattcc tgaatcaata tatcaggtcg
    35521 cattccttgc tcgtcaaaat caattggaac gatctctaaa tgatataact gagccaattc
    35581 aatgaaatta gcgtatgtat atcggtctgt tgctattcta tcacctggag agaaaagtgc
    35641 agaaagtgtg atagccaatc cattttgaac accggaaaca atagatagag attctaagga
    35701 cggaatgact ccttgagttt ttaaccaatt tgctgcagta gtcaattgaa aatttgtgcc
    35761 tttgggatct tggtaattaa gcaaaccaac aagatttggg ttattactag ttgattgaat
    35821 aaacgggaca acgaatttat tacattcttc aaaagaacta accagaccaa aatcaatgat
    35881 atgttcggtt acttcattgg tagagatggt gatggactca aagacattgg gagaaataaa
    35941 tgtgccactt ccaatattcg tatacagcaa acctttctca attccatatt tataagcctt
    36001 gccaacggta gtaaaattta aatctaaata atcagctagc tctctttggg agggtaactg
    36061 agtgtttttc tgtaatttat tctttaaaat atcttgttct aattgttgaa tcaacgatcg
    36121 ataataagga cgcttcaatt tttgtttgtc tggtcgccaa gttaacgggt aattgtcata
    36181 agaattaata ggcattttct ccactcctta aaattgtata ccatacaatt ttaccattga
    36241 ttgtattgat tttagaagtt aatcttttgt gaggagggaa ttgtctatga aaattattaa
    36301 ttttgaggaa gtagtagctt cttttagttt tgaagaagcg attcaagtaa tgaaaaaatg
    36361 tttttttgat tatgaaagtg gtaaaatcag ccaaaatcct cgattggtgg aaattttacc
    36421 tgacggaaaa ggcaaaaata tgtttgcgat gatgcctgct tatttggggg agaacagata
    36481 ttttggcaca aaagtcatta ccgcttttcc ggataatcat cagtatcatt taccttctca
    36541 tttaggagag attttcttgt ttgatgctca aaacggacta cccaaagcat tgataaacgc
    36601 aaatgcagtc acctggattc gaacagctgc tgtatctgcg ctggcaacag attacttagc
    36661 aaatccgcat gcagaaacac ttgctttaat tggagctggt caacaagcat tgtcgcattt
    36721 gactgcgatt tctaccattc gtcccatcac tacagtgttt gtttacgata ttttagaaga
    36781 aagacgaaat acttttatcg ctaaagctaa aaaacagtat cctaaaataa cgtttataaa
    36841 tgcaatatca gtagaagatg cagtacgtcc agcggaaatc atttgtacgt tgacctctag
    36901 taaagaggca tttcttcaaa aagagtgggt aagggaagac gcacatatca atgctgtggg
    36961 cacatttact cctgatacaa gagagataag tacatcgttg atggaaactt ctcaaatcta
    37021 tgtagatgat tactcagctg ccttaacaga aagcggggac ctgcttatag ccatggcaga
    37081 aggagattta gaggaatctt gtattgttgg tacattaggc gaattagttt ctgagaaaaa
    37141 aacattttat aaaggagaat cgaggccgac gattttcgac gcagttggtc tagctattga
    37201 agatctttgt tgtgcagaat atatttataa caaattagag aaaggggctt taaaatgaac
    37261 ttagattatt acgtagttga tgcatttgca gatgaggtgt tcaaaggaaa tccagcagcg
    37321 gtttatgtgc tagaagaatg gctgccagaa ggtacgatgc aaaaaattgc cattgaaaac
    37381 aatttatctg aaacagcatt tacagtgaag aaaaaccaag aatttgagct tagatggttt
    37441 acgccagatc gagaaatcga tctttgtggt cacgcgacat tagcaacagc atttgtttta
    37501 tttaactatt acaaaatacc tgatgaaacg attaaatttt ctactcaaag cggtaatcta
    37561 tttgtgacaa gaattaaaga ttattattac atggattttc ctagtattat gccgaaaaaa
    37621 gtgccgatat tgtctgaata tgaagaagcg attggggcta agattaaaga agcctactta
    37681 gcacgtgatt tatttttcgt attagaagat gaaaaaacgg tggctaaatt gcagccagat
    37741 tttacagcta tcaaaaattt tgaattagga ataggagtca tcgtgacagc agaaagtgtg
    37801 caaaaagact ttgtttctag aaccttcttt ccaaaattaa caatcaatga agatccagta
    37861 tgtggatcag cacattctaa tcttattcct tattgggcag aaagaatgaa taaaacaaaa
    37921 ttgtcagctt atcaaatgtc atcaaggggc ggggatctag aatgtgaatt aaaagaagat
    37981 cgtgtgataa taggaggaaa agcagttttg ttttctaaag gtacctcgtt tatttgattt
    38041 ctttcaaatg aattaaaaat aaattggtgg agagtggcaa ccttatagct acaatggttg
    38101 ttaaaaaaag acgcaaactt tttcaattta atgaaaagtt tgcgtctcat tttaattatt
    38161 ggtgtttgtt ttttattcaa tcaagagtaa aatgccccat actaactatc ctcggatgac
    38221 ttcgatttta taaccatcag ggtcaatgac aaagtagtaa gaaggcgcag tgccaggtaa
    38281 tccttttaag tcagtaatct caagaccagc agctttatgt tgctcgtgta atttttctag
    38341 atcatcagct gctatagcga tatgaccata gccgtctcct agatcatacg caccatgatc
    38401 atagttgtaa gtcaactcta attcatagtc atccccagga agtgtcaaat aaacaagtgt
    38461 aaatttgttt tctggaaaat cacggcggcg gctttcttca aaaccaaatg ccttttgata
    38521 aaattcgatt gatgcttcaa gatctttcac tcgaacacat gtgtgagcca ttttcataga
    38581 ttcatctctc cttttccttt tactcaatca taacaaaaag aagtaaggaa atagttgatt
    38641 tgtgcttgtt catgagaaat ttctcatgta aaatggatag aaaataaaac tgttaaggtg
    38701 gaaactattc atggataaac caatttttgg tgaaaaaaag caatttgctg attatcaaac
    38761 ccgttatgca gcatatattg tcatagaaag agatcagcag attgcagtaa tcgaggctcc
    38821 aaatggtgct ttttttcttc ctggcgggga aattgaagga gaagagacga aagaagaagc
    38881 gattgtccgt gagctgatag aagaaatggg aattgtggca gaaatttctt cttatctggg
    38941 agaagctgat gagtattttt actcgaatta tcgtgcaact tattattata atccaggata
    39001 tttctttgtt gctgattctt ggaagcgtat aggagaacca actgaaaaga ccaataaaat
    39061 ttggtgggtg agccctcaag aagcgcttgt gaaattgaaa cgtggtagcc accgatgggc
    39121 agtcgagaga tggatcgaaa aaaataaaaa ctgaaagaaa gcgagtagat cagctttctc
    39181 tcagtttttt tatttattac agtacatatt ttttgattgc ttcagctaca ccgtgctcgt
    39241 cgtttgatga agtgatgaca tttgctgctt ctttgacaag agaaacggca tttcccattg
    39301 ctactcctag accagcatat tcaatcatgg ataagtcgtt ctcgttatct ccgatagcca
    39361 tgatttcatc ttgatcaata ccaaggtgct gtgcgagatt cgcaactgcc gcacctttac
    39421 ttgcttcttt atttagtact tcgaagtaat agggcgcact tttgaccgtt gtgtatttat
    39481 cacggaaagt ttgcggtaaa cgcgcaattg ctgcatctaa aatttctggt tcgtcgatca
    39541 tcatcatttt gacgatgttc atgtctggtg tcatttcttc aggtgttcga tattttagcg
    39601 gcatcttgac taaacttgct tcgtggatcg tataagcgct gatatctcga ttaggcgtgt
    39661 agatcgcttt gtcatcgatc gaatggagat gactgccgac acggcgtgcc attacttcga
    39721 tctctaggaa atcttcatgt gtcagtccgt gacgggcgat gattttacct gatttcgttt
    39781 gttgtacgag tgccccgtta taagtaataa cgtaatcatt atcttgaaaa aggttcaact
    39841 cgtttaactg ttcctggaca cctggtaagg gacggccagt gcataaaacg atcgaaacac
    39901 cttttgcaac agcagcggca atcgcttctt ttacttcttt tgttacttct cttttctcat
    39961 ttaataaagt accatcgatg tcgatagcga ctagtttgat agacataatt tcctccaata
    40021 tattttaatt tatttcaatc aatgcgccat tacggatatg gctggcaaat tcttgataag
    40081 tttcgtcaaa taaatcataa tgatcacgca aggacggatc aaccatttct tttggaaaga
    40141 aaaatcgctc atctccttgt tcttgtcccg ctaatgcagc aacaagctga ctaacctgtg
    40201 ataattctat caaagttccg tcatttcgca aaatctcgat ttgtgtgcga tgtctgcctt
    40261 gttctgggcg ataaaaatca taaggtagat cgtagctaga attcacagca gtgtaataaa
    40321 caggattata tccgaccttt tctactaaca aagtgagttc ttggactaat tttgaatccc
    40381 ggttgccaga aaaagtagca gatttcagtg gtttacgatt caaaaaacgt ttagctaaat
    40441 catttaaaat aggatcagca gattcagacc attgagtaaa gtaagtgccc aagaccccat
    40501 catcaagttt gaggtattct tctaaagtaa agcttccgtc aagaaatggc agaagtaatt
    40561 gagaatggag ttcaaaactg ctggcatctt cttgatacaa ctcgtgtgcg cgatgaagca
    40621 gatgctccaa aattacttcc ataccacggg aaacaggatg gaagtacact tgcacataca
    40681 tttgatatcg gctaacgata taatcttcca ctgcatgcat gccactcatg gaaaaagcga
    40741 tcccgccttc ataaggacga atcacacgta atattcgggt aagatcaaat gttccatatt
    40801 ctgttccagt gaaataagca tcccgaagca aatagtccat tcgatctgca tcgatctgac
    40861 tagaaatcat ttggacaact tgtgggttgg ggtaagtttt ttggatcaca ctagctacct
    40921 tttcaggaaa accttcttct actcggttaa gaatctgata cacttctgtt tctggagaag
    40981 tgatgatctc tacagtgatg gcttcatgat tcgtatggaa gatatgttca aatgtatgag
    41041 agtaaggacc atgaccgaca tcatgcaaca gtgccgcaca taaagtcacc agccgttcct
    41101 gatcatccca gcctccgttg cctatttttt cttttgaaaa atttcgagaa aagatatcgc
    41161 agattcgtct tgaaatctca taaacgccta atgaatgagt aaaacggcta tgttctgctc
    41221 cgtgaaaagt gaaagaagaa gtgcctaatt gtttaatgcg tcgtagacgt tggacttctt
    41281 tcgaattgat caaatctaag attacttgat gctggacatg gatatagtta tggactggat
    41341 cacgaaaaac tttttccata ggcagcattt gatatttata aggggttgtc ataatgtagc
    41401 tcctttatgt tattacgttg ttccattctc tggatttggt tgttccattg ctccagctgg
    41461 atttcttttt ttagccagtc ggtagaatcc tgtaaatcac ttgcagaata cagcttttca
    41521 aaagcttttg caaatgcttc tttgacttct tttacaaaaa ggggttggtc aagcagttct
    41581 tcaagtgttg ccattgtagc aggatccact gcaggatagc catttgtacc aaagtcttct
    41641 tttaaagcag attgataaaa tcgcttcatg acttgcccac gtttttcctg attaccgttg
    41701 acacttaagt acatcataac agaaatccca tttttgatcc gacgctgagc gataccggca
    41761 aattttttgc catggatgct taaatcataa gttccaggac aataagaatg ggtgatttcg
    41821 aatgcttgta tcggtgcctt tggaaaagcg tatttagtca ataggagcat ttgctcgtaa
    41881 gcgtcatcta tggttatttt ttttgtgtca ctttggggga aaatcaaaga aatattcaaa
    41941 attccttcat ctgatacgat ccctaatcca cctgaatttc tgatcactgg agcgtaacct
    42001 gcatcttcca gtgtttggat cccgtcactt agaaaaggag ttcgaacatc cttcatacct
    42061 aagatgactg tgcagtcata ttgccagaaa tgtaaaaaga tttgctggtg ttctttagaa
    42121 tattccgtta atatatctgt taatgcaaaa ggggaaaagt cgtttttttg ataaatgtgc
    42181 tgatctagtc gaatcgcagg gttcattcaa ccggctcctt tgtataaatt catattttct
    42241 acaatattat actctaaaat caaagagttg ttttggaaaa aaggttttct gtaaaaatgg
    42301 acaagttggt tgacaaaaca aaagaaacta ggaacaatgt agctatgaga agtaaaggag
    42361 aatgaataat ggaattatca caaggaacac cgatttcaat caaattgcgt acaaaagtaa
    42421 aacagcaagg ggaagtgcaa gatttttatt ttgatttgaa agggcaaatg gtgacaattg
    42481 gcgatacgct gtacatacgt tataaagaga ttcaggagga gacgggcgat gagattcctg
    42541 taacgatcaa attagttcca gatggtcatg tacagctgat ccgtgcagga gaaatgcgga
    42601 tgcgtttgaa atttggctat aaagaacggt tagaaacatc ctatcgaaca ccatacggta
    42661 tgatccagat tgctactttt acgaaagaac tgcatgttag tttgaaagac cgtcccacag
    42721 cagggaaggt tcgaatcgat tatgatctgt tcatgggacc ggaaaaaatc ggcgaatatt
    42781 atttgacctt ggattttaca gcgtaaatat aaaagaaaag tttgattttt tgtgtctgat
    42841 tttgtatgat aaggagtaga ctgtgaaagg acgtgtcctg attggaaatt agtgtatttg
    42901 aaggtgcaaa caaaagcgaa ttatcaatga tcgaagtagc acacgcgatc ttagaacaac
    42961 gtggcgatgt catggatttt tctgatttag ctaaccagat ccaaaactat cttgggaaat
    43021 cagacagtga aattcgtgat tcactcgcac aattttatac tgacttgaat attgacggca
    43081 gctttatctc attaggggat aatcgttggg gcttgcgttc atggtatgct atcgattcga
    43141 tcgatgaaga agtaaaccat ggaatggacg aagaggatga agatactcca cgtcgccgta
    43201 aacgcaagaa agtcaacgcc tttatcaatg atgatgaaga cgcgatcgat tacaatgacg
    43261 atgacccaga agatacagat ctgacagaag aagatgacga tgatctgttt gatgacgatg
    43321 atgatgaaga tgaagaaatc gctgcttata attctgactt gcaagaaatc ggagcagatg
    43381 acccgacaga tgatgaagaa gacttgccag gaaatatcga agaagattta agtatcatag
    43441 acgaagacga tgatgatgaa gattatgaag aggaagaatt ttctgactct gaaaaagaat
    43501 aaacattatt ttcttacgag aggttgtgac agagacgatc agcctatcag aataaggagg
    43561 tgtgacacga tttttgtcac accttctttt ttgtatataa aaatcccaag taaatacata
    43621 aaaaataaaa aaattgaaac ttttagcgca ccttgtacgt catattaagt gaggcagaaa
    43681 ggagtggaga atgattttta ctggatataa gaaaaaacgg cagatcgaaa aataccgtca
    43741 cctgctgaat ggactcatcg aaactgatta tcaaaaaatg ttccgtatca cgatgaatta
    43801 cgtacatgat aaagaagagg ccttagatgt gatgcaagat agttttcata aagccctgaa
    43861 ctattttgaa aaagaaaaag agatcgagca ttttagtgca tggttttatc ggatattgat
    43921 ccgcacggca ttagatagtt ggcgcagaca aaaaaggacg cctgtggact tatttgaaat
    43981 tcaagatatc ccccaacagt tacctttaga aacttccgtt gcagagctcc atatgatttt
    44041 agataaaata gacagtccgg aaaaagagat tctgatcctc tacttttttg aaggatttcg
    44101 tttgaaagaa attgcgacta tcttggatat gaatgaaaac acagttaaaa cgaaaatgta
    44161 ccgctcattg aatgctttac gtcaaatcct agaatgaagg agagaagagt gccatgtatt
    44221 cccaaaaaga aaatttaaaa aaactaaaga aaacttataa agaacaagca attcccaaag
    44281 ggcttaaaga ggagatccgc cagcgtttta ttatcgaaga gcaatcattt ataaaagcaa
    44341 agcggagaaa gagacgtctc caagggttcg gagtatcttt ggctatcgta atgattacaa
    44401 caagtagcct tctttttaat agtcaagttc gaagctttgc agaagattta cccatcttag
    44461 gatcagtcat tgaattgatc ttaggcgaac gctttactga tcgatctgaa aaaatcgata
    44521 ttcaggtacc gaagatcaat acacaaaatg agaaagaaaa taaaacaatt catggattaa
    44581 atcaaaaata ctttcgcgaa ggacaagcag attttgaaaa agctgaaaaa gaatatggaa
    44641 attttgaaac ggatcattac caagttttgg gagattatca gaaaatcgta gacgataacc
    44701 ggtttctcgt gattgaaagg cagatcaccc aaacagcagc agatagccat gttgaaaaaa
    44761 gatacgacac aatcgacaag aaaaacagtg tccagctctc acttccactt ttattcaaag
    44821 atgacaccta tctatctgtt ttgacaaaag aagtcaaacg gcagatggcc gaacaagtca
    44881 aggaagatcc atctaagtac tattggactg agcaagatat tcaagaaggg acgatagaaa
    44941 aaccaacact tgttacgcct acacgaagtt tttatttgaa caaagagcat caattagttt
    45001 tgactttttc tcaatacgaa attgctcctg gttatatggg tacaccagaa tttgtcattc
    45061 ctaagtccgt gacaaaaacg attttggcat cggaagatta tttggatcat tagacgagaa
    45121 gtagttgcga ctagcagttt caattttcaa gtaagtacaa gtaaataata agaagagaaa
    45181 aagagaaaga agagatatag tgaaaagaaa ttatttagtt atcagtatta ttgctttatc
    45241 cgtgcttttg tttttcgaaa ttacttcggt ggcctccttg atcaccgaag taaaaggaca
    45301 aacacactct tcggagcatt cgtcacaatc tttcaaacaa tcagaacaat caaccattaa
    45361 aagccaatca actgaaacag ctaacgtcaa agaagccatt caagaatcag cggaaaaggt
    45421 acaaagtcag tcatcacaat caacacaaga cagtacaaaa acgagccgag atccggctgt
    45481 caaaagcgtc gcaatcagct ttgatgatgg accaggagcg accacaacac cgcagcttct
    45541 gcgaatctta aaagaaaaaa acgtgcatgc cacttttttc gtcttaggag aaaatacggc
    45601 gcagcatcct gaaatcgtga agcagacagc tgaagcaggg cacgagattg gcaatcacac
    45661 atacgatcat cagaatctgg ccactctttc tgcccagtcg atgacggagg aagtgacgaa
    45721 agcagacact gagatcaaaa aagtcactgg caaaaccccc acttttgttc gtccgcccta
    45781 tggttctgtc acgaatgtag gagcaacgat catccagcga ccgatcatcg aatggtctgt
    45841 tgattcagaa gattggaaga caagaaatcc tgatttgatt ttgcagaaga tccaagcaac
    45901 agtatacgat ggggcaatta ttttattcca tgatatctat cctgaaacga ttcgtgccgt
    45961 tcctcaagtg atcgattatc tgaaagagca agggtatcgc atcacgacag ttggggattt
    46021 attagggcat ccaacggctg tcgagaacta ttatggcaga aacgatcatc ggccagttca
    46081 gtaagtgaga caagtatctt taataaataa cacattttaa taagtagttg aacacataac
    46141 taccttactt gcaaaggctt aacaatatct atacaggtac aacaaaaaac tgtccaccaa
    46201 ttttctttgg cggacagttt tcacttaaaa ataaagaagc aactattcgt aaattatgct
    46261 aaaatagcag tagaacgcgt cctgagggaa tcgaaccccc gtctcaagaa ccggaatctt
    46321 acgtgatatc cactacacta aggacgcaag cactgggata attgtaacta aacagataaa
    46381 aaattacaag gggattggac aaaaaaatga aatttgagca aaatttttca caaaaacagc
    46441 agcagacaca gaaactagcc atgacgcaac agttgcaaca gtccatccaa gttttacaat
    46501 ataacagtga ggagctgttg gcattcgttg agaatcaagc aatggaaaat ccattggtgg
    46561 aagttgttga gccggaatgg cagccagatt acataaaagc ttcttcatct tcttatgaag
    46621 gagaagagac aaattaccta aatcagattc ctgatacaaa agggtcttta tttgattcat
    46681 tgatcgaaca agtccatttg aattaccgag atactttttt gaggaaaatc gttctttatc
    46741 ttgtagaata catcgatttg aacggatttt tgacgattag tttagaagaa gccggaaaag
    46801 agattggagc tacgcctatc caaatgctcg atgcgttgac tctgattcag caattagaac
    46861 cagctggagt aggtgcacgt agtttgcaag aatgtctcat gcttcaaaca gaacgagatg
    46921 attatgcgcc ggaattagct tatatcgtgt tggaagaatg ttttgaggaa ctggtggagc
    46981 gaaaatggaa agaaatcgca caacgttttt ctgttgatct acatgctgtt cagcagatat
    47041 tcgactattt acaaacgttg agtccaagcc ctggccggat tttcgaccgt agcagcgaat
    47101 tgtacattat tcctgatgtc cgggtattag tggacgacga taaaaatgta caagttatct
    47161 caaaccgaaa aaatcagcca aatatacgct ttcaagagag ttacttcaaa caaatgtcac
    47221 aacaagcaga taaagaaact gaaaattatt taaaagaacg gaaacaggaa ttcgaatggt
    47281 tgaagaaaac gatcctacaa cgtggggata caattttgcg ggttgctcaa gtcattgttt
    47341 cccggcaaaa agctttcttt atcgacaagg aacgtccaat caagcctctt acgttaaagg
    47401 aagttgcaac tgagatagat gtgcatgaat ccacggtcag tcgtgcagtc aacgggaaat
    47461 atttggaaac agacttcggt gtatttgaat taaaaaaatt tttcactaca cgaattccta
    47521 cgaatagtac agaacagaca gaagaccttt cagcagatac agcgaagaaa aagctgcagg
    47581 aattagtcga tcaagaagac aaaaacaagc cgttgtctga ccagaaattg gttgaattgc
    47641 tgaaaaaaga tgagatagcg atctcaagac gaacagtagc aaaatatcgt gatttattag
    47701 gaatcccgag ttcatcaaaa agaaaacgtt atgataacta atcagtcaaa agactagaaa
    47761 aagtatttca ctttttctag tctttttagt tgaaaaacga gagcaaaact gttagactta
    47821 cagtcgtgag gttgagattt ccctttattg atgtgaaatt cgaatagtta atttcttttt
    47881 ttatcgtata tgggtcgttt taagtctaca ttggacgtaa agtgtccaac taaggagatc
    47941 gctatgctgg atgaaataaa aatgattgaa tctgttgcac cagatattat cgaagtgttg
    48001 caagaacgct ataaaatttt acgaaatatc tattggatgc agccgattgg acgtcgaagt
    48061 ttatcggaaa gtatggggat cacagaacga gtattgcgaa cagaaacaga tcttttgaaa
    48121 aatctgaatt tgatcgacac ctcaaaaagc ggtatgacgc tgacaactaa gggcgaagaa
    48181 gtttatcaaa gccttgaaaa cttcatggat cagcttttag gtacgcatca aaccgaacaa
    48241 cagttggcag aatattttgg taaccaacgc tgtatcgttg tttcaggaaa cagcgaagag
    48301 cagaccaaag tggctgatgc attcggcgaa gcgctgagcg aagccctaga ccgactactt
    48361 ccagaaggcg agaatatcat cgctgtgatg ggaggaacta ctatggctgt ggtagccgaa
    48421 caattgtcta atctggaaaa taagaaacgg cataacctgt ttgtccctgc aagaggcggg
    48481 attggtgaag cgataactgt acaggcaaat tctgtcagtg caagaatggc tgctaaagca
    48541 aacggtaacc accgtgcact ttatgttccg gaacaattaa gtctggcaac ttacaattct
    48601 ttactcaatg agccatctat ccaagaagtc ttaaacttga ttagtgaagc gaattgtgtt
    48661 attcatagta ttgggcgtgc attacacatg gcagcacgtc gtaagatgac tgaaaaagaa
    48721 ttagtcatgc tgaaacaagc aaatgctgtt gcggaatctt ttggctactt tttcaatgaa
    48781 aaaggtgaag tcgtttataa ggtccctaga atcggcatag aattgcaaga tttggaaaaa
    48841 gtcccgatca tcatggcaat cgcgggcgga aaatcaaaag ctaaagcaat tcgagcttat
    48901 atgaaaaatg caccaaaaca aacgtggctc atcactgatg aagctgctgc aaatgagatt
    48961 ttaaaagggg taacccttta aaataaatat ttttttgatt ttcataagga ggaaatctta
    49021 aatgacagtt aaagtaggta ttaatggttt tggacgtatt ggacgtctag cattccgtcg
    49081 tatccaagat gtagatggaa tcgaagtagt agcaatcaac gacttgacag atgctaaaat
    49141 gttggcacac ttgttaaaat acgacacaac tcaaggacgt ttcaacggaa cagttgaagt
    49201 tcatgaaggt tcattcaacg taaacggaaa agaagttaaa gtattagcta accgcaaccc
    49261 agaagaatta ccatggggcg aactaggcgt agatatcgtt ctagaatgta ctggtttctt
    49321 cacttctaaa tcagcagctg aaaaacattt aacagctggt gctaaacgcg ttgttatctc
    49381 tgctcctggc ggaaacgatg ttccaacaat cgtttataac acaaaccacg aaacattaac
    49441 tggtaaagaa acagttatct caggtgcttc atgtactact aactgtttag ctcctatggc
    49501 taaaacattg aacgacaaat ttggtgttgt tgaaggatta atgacaacta tccacgctta
    49561 cacaggtgac caaatgactc tagacggacc tcatcctaaa ggtgacttcc gccgtgcacg
    49621 cgctgctgct gcaaacatcg ttcctaactc aacaggtgct gctaaagcta tcggtttagt
    49681 aattcctgaa ttgaacggta aattagacgg agctgctcaa cgtgttcctg taccaacagg
    49741 ttcattaaca gaattagtaa cagttcttga aaaagaagta actgttgacg aaatcaatgc
    49801 agcaatgaaa gaagcttcaa acgaatctta cggatacaac acagacgaaa tcgtttcttc
    49861 agatatcgtt ggtatgactt acggttcatt atttgatgct acacaaacta aagtaatgac
    49921 agttggcgac aaacaattag ttaaaactgt tgcttggtac gacaacgaaa tgtcatacac
    49981 tgcacaatta gtacgtactt tagaatactt cgctaactta taagatagac aaacgtacaa
    50041 gtgtaaatta tagacatgta catttaaaag cggggaagca atcgcgcttc ttccgctttt
    50101 tttgataata agtttattca ggaggaaata aaatggctaa gaaaacagtg aaagatatcg
    50161 atttaaaaga caaaaaagtt cttgtccgtg ttgacttcaa cgttcctttg aaagacggcg
    50221 tgatcactga cgacactcgt atcaaagcag cattgccaac aatcaactac gttctagaac
    50281 aaggcggaaa agcaatcctt ttctctcacc ttggacgtgt aaaaacagaa gaagataaag
    50341 aaggaaaatc tttagctcca gttgcaaaac gtctaggcga attattaggt aaagaagtaa
    50401 cattcgtacc tgaaactcgc ggagaacaat tagaagaagc aatccgcaac atgaatgacg
    50461 gcgacgttgt cgtattcgaa aatacacgat ttgaagatat tgacggtaaa aaagaaagca
    50521 aaaatgatac agaactaggt aaatactggg cttcattagg cgatgtattt gttaacgatg
    50581 ctttcggtac agctcaccgt gcacatgctt ctaacgtagg tatcgcttca actggtatcc
    50641 caacagttgc tggattcttg atggaaaaag aaatcaagtt catcggtgaa gcagtagaag
    50701 aaccaaaacg accaatgatt gcaatccttg gtggcgcaaa agtttctgat aaaatcggcg
    50761 taatcgaaaa cttgattcct aaagcagata aaatcttgat cggtggcgga atgacttaca
    50821 cattctacga agcaaaagga atcaagatcg gtaactctct agtagaagct gataaagtgg
    50881 aactagcaaa agaattaatc gaaaaagcag gcgacaaact tgtcttgcca atcgacaatg
    50941 tctgtgcacc agaattttca aatgatgttg aaacacaagt aatcgaagga gacattcctg
    51001 atggtttgat ggctttagac atcggcccag catcagtaaa attatttgct gatacattac
    51061 aaggtgcaaa aacagttgtt tggaacggac ctatgggtgt atttgaaatg agtaactttg
    51121 ctaaaggtac aatcggtgtt tgtgaagcaa tcgctaactt agaaggcgca acaacaatca
    51181 tcggtggcgg agactcagct gcagcagcag aacaattagg atttgctgac aaattcacac
    51241 acatctcaac aggtggtggc gcaagcttgg aattgcttga aggtaaagaa ttaccaggac
    51301 tagcagcaat caacgataaa taaacgacca agtttgctca attctgacga gtaatcgatc
    51361 aaaaggtgaa gggagttttc atgactccct agccattttt caataaatta aggagtgtgt
    51421 tcctcaatgc gtaaacctat tatcgcaggt aactggaaaa tgaacaaaac tgcatcagaa
    51481 gcaaaagaat ttgctgaagc agtaaaaaac aaaatccctt caaatgacaa agttgattca
    51541 gtcatcggat ctcctgcatt attcttacaa gaattaatga catcagctga aggtacagaa
    51601 ctaaaaatct cagcacaaaa ctgctactgg gaaaactcag gtgcgttcac tggtgaaact
    51661 tcaccagcag ctcttgctga tctaggtgtt cattatgtga tcatcggaca ttcagaacgt
    51721 cgtgaatatt tccatgaaac agacgaagac atcaataaaa aagcaaaagc tatctttgca
    51781 aatggtatga caccaatcct atgctgcggc gaatctttag aaacctatga agcaggcaaa
    51841 actgctgaat ggatcgaagg acaaattaca gctggtttag ctgatctttc agctgaacaa
    51901 gtgtcaaaca tggttattgc ttatgaacca atctgggcaa tcggtactgg taaatcagct
    51961 gacgcacaaa tcgctgacga aatttgtgga gttgtacgtc aaacagttga aaaactttat
    52021 ggaaaagaag tatcagaagc agttcgtatc caatacggcg gttctgtaaa accagaaaat
    52081 attgctgaat acatggcaaa agaaaatgtt gacggtgctt tagtcggtgg cgcaagcttg
    52141 caagcagatt catttttgtc attgttagac gctgtaaaat aattgttgaa aatttgcgaa
    52201 aaatgcaaga aatgtttgca ctaatgagca aaattaacta aaatcgtata tgagggaaat
    52261 cccttaggaa aaaacaaact caaaggagag acaaaacatg tcaattatta ctgatgttta
    52321 cgctcgcgag atcttagact cacgtggtaa cccaacaatc gaagtagaag tatacacaga
    52381 aagcggagct tttggccgcg gaatggttcc ttcaggtgct tcaactggtg aatacgaagc
    52441 agttgaatta cgtgacggag acaaagctcg ttatggcggt aaaggtgtaa ctaaagctgt
    52501 cgacaacgta aacaacatca ttgctgaagc aatcattggc tacgatgttc gtgaccaaat
    52561 ggctatcgac aaagctatga tcgctttaga cggaactcct aacaaaggta aattaggtgc
    52621 gaacgctatt ttaggtgttt ctatcgctgt tgcacgtgca gctgctgact acctagaagt
    52681 acctttatac cactacctag gcggattcaa cacaaaagta ttgccaacac caatgatgaa
    52741 catcatcaac ggcggatcac atgctgataa ctcaatcgac ttccaagaat tcatgatcat
    52801 gcctgttggc gctccaacat tcaaagaagc tctacgtatg ggtgctgaag tattccacgc
    52861 attagcttca atcttgaaag ctcgcggatt agcaacttct gttggtgacg aaggtggatt
    52921 tgctccaaac cttggttcaa acgaagaagg ttttgaagta atcatcgaag caatcgaaaa
    52981 agctggctat gtacctggta aagacgttgt tcttgctatg gatgctgctt cttcagaatt
    53041 ctacgacaaa gaaaaaggtg tttacgtact agctgactca ggcgaaggcg aaaaaacaac
    53101 tgacgaaatg atcaaattct acgaagaatt agtttctaaa tatccaatca tctcaatcga
    53161 agatggatta gacgaaaacg actgggacgg attcaagaaa ttaactgacg tattaggcga
    53221 caaagttcaa ttagttggtg acgacttgtt cgtaacaaac actcaaaaat tatctgaagg
    53281 tatcgaaaaa ggaattgcta actcaatcct tatcaaagtg aaccaaatcg gtacattaac
    53341 agaaactttc gaagctatcg aaatggctaa agaagctggc tacacagcag ttgtatctca
    53401 ccgttctggt gaaacagaag attcaacaat ctctgatatc gctgttgcaa caaatgctgg
    53461 ccaaatcaaa actggttctc tatcacgtac tgaccgtatt gctaaataca accaattact
    53521 acgtatcgaa gaccaacttg gtgaagttgc agaatacaaa ggtttgaaat ctttctacaa
    53581 cttaaaaaac aaataattct tttctaatga agatacatga tcgactattg aaagatagtc
    53641 gagtatgatc acttagttaa gtaatcgaac tctctacttg ctgaaatatc agcaggtaga
    53701 gagttt
//
LOCUS       DBBGRF010000016        53539 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000016 DBBGRF010000000
VERSION     DBBGRF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.016"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..878
                     /locus_tag="ACIZD4_001037"
     CDS             <1..878
                     /locus_tag="ACIZD4_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC5989987.1"
                     /translation="SLSQLLPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENR
                     QLNPLRDYFLRYPIKVREQVRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRA
                     FTNHRIQVMKTFKKGDRRSKHLKKYWKLLQKNAWELKGQHRYWRPSFRDHLTEAEIVD
                     RLLSYDDSLKRGYEVYQDFLSVIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYQT
                     EIKRALRVPYSNGPIECLNNHIKVLKRIAYGYRNFQNYRERIFLYRGKYFKKTKNTTQ
                     LTKARTTTRLDKIAV"
     gene            complement(1119..2735)
                     /locus_tag="ACIZD4_001038"
     CDS             complement(1119..2735)
                     /locus_tag="ACIZD4_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HGC5989988.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            2853..3071
                     /locus_tag="ACIZD4_001039"
     CDS             2853..3071
                     /locus_tag="ACIZD4_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989989.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            3266..3727
                     /locus_tag="ACIZD4_001040"
     CDS             3266..3727
                     /locus_tag="ACIZD4_001040"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC5989990.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(3920..4159)
                     /locus_tag="ACIZD4_001041"
     CDS             complement(3920..4159)
                     /locus_tag="ACIZD4_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5989991.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4183..5706)
                     /locus_tag="ACIZD4_001042"
     CDS             complement(4183..5706)
                     /locus_tag="ACIZD4_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HGC5989992.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(5724..5846)
                     /locus_tag="ACIZD4_001043"
     CDS             complement(5724..5846)
                     /locus_tag="ACIZD4_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HGC5989993.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(5876..6859)
                     /locus_tag="ACIZD4_001044"
     CDS             complement(5876..6859)
                     /locus_tag="ACIZD4_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HGC5989994.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(6883..7032)
                     /gene="rpmG"
                     /locus_tag="ACIZD4_001045"
     CDS             complement(6883..7032)
                     /gene="rpmG"
                     /locus_tag="ACIZD4_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGC5989995.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(7053..7430)
                     /locus_tag="ACIZD4_001046"
     CDS             complement(7053..7430)
                     /locus_tag="ACIZD4_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5989996.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(7462..7641)
                     /gene="rpmF"
                     /locus_tag="ACIZD4_001047"
     CDS             complement(7462..7641)
                     /gene="rpmF"
                     /locus_tag="ACIZD4_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGC5989997.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(7656..7925)
                     /gene="rpsN"
                     /locus_tag="ACIZD4_001048"
     CDS             complement(7656..7925)
                     /gene="rpsN"
                     /locus_tag="ACIZD4_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGC5989998.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(8448..10214)
                     /locus_tag="ACIZD4_001049"
     CDS             complement(8448..10214)
                     /locus_tag="ACIZD4_001049"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5989999.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(10174..11928)
                     /locus_tag="ACIZD4_001050"
     CDS             complement(10174..11928)
                     /locus_tag="ACIZD4_001050"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990000.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(12038..12607)
                     /locus_tag="ACIZD4_001051"
     CDS             complement(12038..12607)
                     /locus_tag="ACIZD4_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGC5990001.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(12625..14040)
                     /locus_tag="ACIZD4_001052"
     CDS             complement(12625..14040)
                     /locus_tag="ACIZD4_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990002.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(14051..14719)
                     /locus_tag="ACIZD4_001053"
     CDS             complement(14051..14719)
                     /locus_tag="ACIZD4_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGC5990003.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(14849..15433)
                     /locus_tag="ACIZD4_001054"
     CDS             complement(14849..15433)
                     /locus_tag="ACIZD4_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5990004.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(15764..15997)
                     /locus_tag="ACIZD4_001055"
     CDS             complement(15764..15997)
                     /locus_tag="ACIZD4_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGC5990005.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(16012..16962)
                     /locus_tag="ACIZD4_001056"
     CDS             complement(16012..16962)
                     /locus_tag="ACIZD4_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HGC5990006.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(16959..17801)
                     /locus_tag="ACIZD4_001057"
     CDS             complement(16959..17801)
                     /locus_tag="ACIZD4_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGC5990007.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(17803..18522)
                     /locus_tag="ACIZD4_001058"
     CDS             complement(17803..18522)
                     /locus_tag="ACIZD4_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGC5990008.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            19070..19372
                     /locus_tag="ACIZD4_001059"
     CDS             19070..19372
                     /locus_tag="ACIZD4_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990009.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNTFKIT"
     gene            19444..20670
                     /locus_tag="ACIZD4_001060"
     CDS             19444..20670
                     /locus_tag="ACIZD4_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5990010.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYETIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(20758..21150)
                     /gene="rpsI"
                     /locus_tag="ACIZD4_001061"
     CDS             complement(20758..21150)
                     /gene="rpsI"
                     /locus_tag="ACIZD4_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGC5990011.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(21166..21594)
                     /gene="rplM"
                     /locus_tag="ACIZD4_001062"
     CDS             complement(21166..21594)
                     /gene="rplM"
                     /locus_tag="ACIZD4_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGC5990012.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(22128..22595)
                     /locus_tag="ACIZD4_001063"
     CDS             complement(22128..22595)
                     /locus_tag="ACIZD4_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGC5990013.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(22715..24253)
                     /locus_tag="ACIZD4_001064"
     CDS             complement(22715..24253)
                     /locus_tag="ACIZD4_001064"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HGC5990014.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            24333..25019
                     /locus_tag="ACIZD4_001065"
     CDS             24333..25019
                     /locus_tag="ACIZD4_001065"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGC5990015.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(25220..25747)
                     /gene="msrA"
                     /locus_tag="ACIZD4_001066"
     CDS             complement(25220..25747)
                     /gene="msrA"
                     /locus_tag="ACIZD4_001066"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGC5990016.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(25831..26508)
                     /gene="pgmB"
                     /locus_tag="ACIZD4_001067"
     CDS             complement(25831..26508)
                     /gene="pgmB"
                     /locus_tag="ACIZD4_001067"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HGC5990017.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(26505..27635)
                     /locus_tag="ACIZD4_001068"
     CDS             complement(26505..27635)
                     /locus_tag="ACIZD4_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGC5990018.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(27635..29818)
                     /locus_tag="ACIZD4_001069"
     CDS             complement(27635..29818)
                     /locus_tag="ACIZD4_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HGC5990019.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(29815..30840)
                     /locus_tag="ACIZD4_001070"
     CDS             complement(29815..30840)
                     /locus_tag="ACIZD4_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC5990020.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(30885..31712)
                     /locus_tag="ACIZD4_001071"
     CDS             complement(30885..31712)
                     /locus_tag="ACIZD4_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGC5990021.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(31709..32776)
                     /locus_tag="ACIZD4_001072"
     CDS             complement(31709..32776)
                     /locus_tag="ACIZD4_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HGC5990022.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(32802..33638)
                     /locus_tag="ACIZD4_001073"
     CDS             complement(32802..33638)
                     /locus_tag="ACIZD4_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990023.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(33635..34504)
                     /locus_tag="ACIZD4_001074"
     CDS             complement(33635..34504)
                     /locus_tag="ACIZD4_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990024.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(34574..35857)
                     /locus_tag="ACIZD4_001075"
     CDS             complement(34574..35857)
                     /locus_tag="ACIZD4_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5990025.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(35871..37556)
                     /locus_tag="ACIZD4_001076"
     CDS             complement(35871..37556)
                     /locus_tag="ACIZD4_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HGC5990026.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            37831..38856
                     /locus_tag="ACIZD4_001077"
     CDS             37831..38856
                     /locus_tag="ACIZD4_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5990027.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(39451..43104)
                     /gene="rpoC"
                     /locus_tag="ACIZD4_001078"
     CDS             complement(39451..43104)
                     /gene="rpoC"
                     /locus_tag="ACIZD4_001078"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGC5990028.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(43183..46800)
                     /gene="rpoB"
                     /locus_tag="ACIZD4_001079"
     CDS             complement(43183..46800)
                     /gene="rpoB"
                     /locus_tag="ACIZD4_001079"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGC5990029.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            47528..48496
                     /locus_tag="ACIZD4_001080"
     CDS             47528..48496
                     /locus_tag="ACIZD4_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5990030.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            48514..49419
                     /locus_tag="ACIZD4_001081"
     CDS             48514..49419
                     /locus_tag="ACIZD4_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990031.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            49416..50222
                     /locus_tag="ACIZD4_001082"
     CDS             49416..50222
                     /locus_tag="ACIZD4_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990032.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            50379..51347
                     /locus_tag="ACIZD4_001083"
     CDS             50379..51347
                     /locus_tag="ACIZD4_001083"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HGC5990033.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(51664..52188)
                     /locus_tag="ACIZD4_001084"
     CDS             complement(51664..52188)
                     /locus_tag="ACIZD4_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HGC5990034.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            52475..>53539
                     /gene="scm"
                     /locus_tag="ACIZD4_001085"
     CDS             52475..>53539
                     /gene="scm"
                     /locus_tag="ACIZD4_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HGC5990035.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        16026 a        10919 c         9130 g        17464 t
ORIGIN      
        1 tttctttgag ccagctgtta ccagaagtgg tgtgtttcga tgaattcaaa tcagtgaaaa
       61 atgtctcggg agccatgagc tttgtcatga tggacggcaa gacccatcaa ctgattgata
      121 ttgtggaaaa tcggcaactc aatcctttac gcgactattt cttgcgctac cctataaaag
      181 tccgtgaaca agtgcgtcta gtggtttcag atttctatac accctatcgc acattggtga
      241 aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt tcatattagc caacacattg
      301 gtcgggcttt taccaaccac cgaattcaag taatgaagac ctttaaaaaa ggggatcgtc
      361 ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa gaatgcgtgg gaattgaaag
      421 gtcagcatcg ctactggcgt ccgtcatttc gagatcatct gacagaagca gagatagtcg
      481 atcggctatt atcttatgat gattccttaa agcgaggcta cgaagtctac caggattttc
      541 tttccgttat cagaagacaa gatgttcctg aattcgtcgc gctcctaaaa gaagactaca
      601 aggagttgcc agagcactac caaccagtgt tcacgacctt caagaaatac caaacagaaa
      661 tcaaacgagc gttgcgcgtt ccctattcca acggccctat agaatgtttg aataaccata
      721 tcaaagtact aaaacgaatt gcctatggct atagaaactt tcaaaactac cgagaacgaa
      781 tctttttata tcgaggaaaa tattttaaga aaactaagaa tactacccaa ctgactaaag
      841 ccagaacaac aacacggcta gacaagatag ctgtctagcc gtgtgagtat ctcgattatt
      901 ctattgaatt tcttcaccaa cactcattga cgaagagcca aaataagtaa tctaaccgac
      961 tgttaactaa accattgcag gtcccgttaa agatacttgt gcctgttgtc accgcttctt
     1021 tttcttgtcc acaagcgctt aacacactta ataaagcccc tgctattatt aataataata
     1081 tctttttctt attaaaaacc tcctcatcta tttccagatt agtaaatgta gtaatctgtg
     1141 ctttcttttt tctcaatact aataactaac ttatggggta aacaaatact cgtttgaccg
     1201 ggttttgaga tccatccagt tctaaccgcg atttgatcag gactattatc ttctttaact
     1261 cgaattcttc catctttaat ctcaacaata ttatattgtc ccttcgcagg atgataattc
     1321 acgagtttat gattgatctt atccaaatcg aagcgatcca tttccttgcc atcaattcga
     1381 acgatggcat atttgatagc atcttcagtt gtttcattct ccttttctat agagaataca
     1441 aataagggaa taaaagaggt aataatcaaa atgccaataa ttatgacatc gcctatcttg
     1501 acaccagctt ttcttaaaaa tttcattaac gatatctggc taaacatatt agactttttc
     1561 catggaaatg gtgaaatttt tcggaaatta tctgcattaa gagaatcagt taaacaaccc
     1621 tcaagttgtt ccttaataca ttgttgatcc atcttcatac caataaaaac tagtttatta
     1681 atgcgttcac caaacaacgg atgccaggct tccttcaatt cgggattttt ttgtataatc
     1741 atttgacact caattttagg taaactagct acccaataat ttaatgattc aatactttta
     1801 tagctacccg atgtttcaaa gatcgtcgaa aaatcactat gttgggcaaa ccaaagaaac
     1861 ccttttgctc ttgtaatatt gccaggaaaa tttttatccg taagatgggc aaatttttgt
     1921 gcgtcaagga gtaaccgatt tcgatagata aaacttgaga taccatattc ttctgtttca
     1981 ggaatatgat tttgatagcc aagctctaac tctttgaacc agcccactga ataggaagtc
     2041 tcatctatat taaaaagatt tgtatttaga attttcgata agtctacttc acctttaatt
     2101 gtcctaatta ttttggcatt ggactgtaac ttagcaatta gaccgttaat tttgtaaatc
     2161 gtcttggttg acactaagtc actattattt aaaagtaata tgttacaaca ctcgaattga
     2221 tcaattaaca agccacgaat atcctgttct tcttcaacta cattaccttc agcttttctt
     2281 tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac gttttacatc cactactata
     2341 ataatggcac caatctctaa tcgttgggtc aaatcaatgt ctaaagggtt tttagctaat
     2401 ataattgctt gaataattgg aattggtttg ctgattcctg aagcttcaat aacaatttga
     2461 ttcaagtcag aaaattgcac taattgatct agttcaacaa tcaaatcttc gcgtaatgta
     2521 caacaaatgc atccattcgg catcgaaaca agtttttctc cagttctttt aaaacctttc
     2581 ttgtcgacta ataccccatc aacatttact tcccctatgt catttacaat gacagcaatt
     2641 tcctttccgt gatcaccgta cagaatatga tttagaagta tcgtttttcc tgaaccaaga
     2701 tagccagtta agattgtaat aggtattttt ttcataggga acctctttct ataccttgaa
     2761 tttacacttt aagtgcaaca cataaaaatg agtcataatc gatatccaac tagtataagt
     2821 ttgtcgagaa cactcctaga aggaaaataa ttatgagcca gtatcgtcat cttactatac
     2881 tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt ttctattagt ataattggca
     2941 acgacattca gcatagcccg tttactattt tacatgaact gagaagaaac aagaaaaaaa
     3001 ctattcacct tccaaagcgg aaaaaaatta tgcttatcga agaaaaaaat gcggacgtta
     3061 tcacattcta aatgatccgt gagtttggtc aattgttcgt catttatttg tcgattttca
     3121 gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa catatggact tttcaattag
     3181 ttttatcacg atctaacgtg caatttgcaa tgatcttttc gatacagaac ccctctcaca
     3241 cggcaataaa ggcctgatcc gttcattgca ccatcgagga aaaacaagac atacaaaaaa
     3301 tcatgtcgag tctcgtggaa agatttgcct tactcattcg atccatggcc gtccaaaatc
     3361 cgcagatgat agaagtgatt ttggtcattg gaaagccgat attgtagctg gcaaaactgg
     3421 tggtacttgt ttagtgactt tgacagacag aaaatcatgc ttccttttag caggaaagaa
     3481 ggtccccaga aagaaagccg cttatgtgag cgagaaaatg attgaacttt taagcagtat
     3541 tccaaatgag gcggtcaaaa cgatcactcc agatagagga aaagaattct ccaatcattt
     3601 cgcagttaca gaagcattga ataatatgcc cttttatttt ccagatcctc atgcccttgg
     3661 caacaatgaa caaattaaaa tacgaataga ctcattcgag aatacttgcc aaaatcgaaa
     3721 gagatagcta cggtagataa ctcaacgata aatcagatga ttgaaaaact gaataacaga
     3781 cctagaaagt gtttagattg gagaacacct tatgaagtct tctttgataa agtgttgcgc
     3841 ttgatttgac aattcaagac ataataaaaa gcagatcaaa tccaaataag ggaaaaatga
     3901 tctactctgg tattatcaat taattggcca agctattatg ccgttttgct aaacgtctac
     3961 ttcttccagt attgaccttg ataaaacaac aatcaggatc ccgttttaat actctatgaa
     4021 ctgtgtcaat actaacatgt aaagttgcag caatatcagc taatgtactc ccatttaatc
     4081 tcatttgctt tgcaaatcga taacgccgat aagcatcaat attcttggaa tccatagaca
     4141 ataatacttt tcttaccatg tatttcctcc aaaaattgaa ttttaatgag ccatcatttc
     4201 ttgagcaatt tcatgtttag acaatgaagc tggatagaaa gtaggccaat tatgcaattc
     4261 attatagagt ttttcttgac tttctccacc aaagaaaata tggaaatgct ctgccttact
     4321 tggtgcaatt ccatgatcac taaattgaat atatttaaaa cgaccagcac ctgcatcatc
     4381 agtttcaaaa ttaaaacgaa caccacggtt tcctttttca taattcaaaa ttttgtatcc
     4441 aacatatttg tatgtgtatt gatgatgttc accgttgact acaaaatcaa tggtgttgtc
     4501 tttaatgttg atagtatcaa tatctgtctt atagccagta gtataataat ctttgtactc
     4561 ggcagctgtc atgtctttat tgatttttgc tttgtaatcg aaaacttcat ccaaaattcc
     4621 atcttttaac aacggataaa cagattgcca ttcgcctgta taatcactca attcgcgatc
     4681 cttcacatcg gcatctttaa agtacccatt agcaactgtc ttttcatcct tcgcttcttt
     4741 ttctggaact acctcttcac cagcaaccat agttgttttt tctaacgctt ttagattgtc
     4801 ttccattact gaaacataat cttcaccatt atccatttgt tcttttgtaa gactttcaag
     4861 aggattcagt acttccaatt ttatcccagc ttcgttggcc aaagtttttg caattttatc
     4921 attagcattc ttttcaaagt aaatataatt gatcttattt tttttaacat actcttttaa
     4981 ttcagctaat cgaccagaag atggctcttc ttcaggactt agtccagcaa taggaacttg
     5041 tttcaatcca taatccaaag ctaaatatcc aaaggctgcg tgttgcgtca caaaactttt
     5101 ttgtttcgct tctttaagac tagtggtata gtcagcatcc aaccgtttca gtttagtcaa
     5161 atacttttca gcatttgtct caaatacttt tgcttttttc ggatacaatt taactaactg
     5221 atccttgata tttgaaactt ccttaattgc cattttgggt gaaacccacg tatgaggatc
     5281 tagttcatga tggtgatctt cttctccgtg atcatgatct tcttcttcac tacctggcaa
     5341 taaaatcatg tcttttgttc cttctactac attaggccca gctttcttcc aactttcttt
     5401 agcttttggt acccatgatt ccatgttttc gttatgatat acaaaaacat cagcatcatg
     5461 agcttttgcc atatccttag ctgagggctc atagtcatga ggttctgatc ccgctggaac
     5521 cattaaatcc acgttcgctt catcgccgac gatgtttttg gtgaaatcat acattggata
     5581 gaatgttgtt acaatttcta attttccatc tttatcattc gatacttttg catcattagt
     5641 gctggagcaa gctcccaata atcctagagc tgctatccca ataagtccta cactgatttt
     5701 cttcattctt tttccttcct taattatgct aatttcttca ttttatttcg tttatgttct
     5761 ttgataattt ttaatgccct ttttctagtt ttaatattcg ggcttttaag tcgtcgatat
     5821 gcactagata tatccgtttt ctccattaga aattaccccc aatcactact tatcattatt
     5881 tgctttccgc cagtaattta tcaaaactct gtttgatcct ttcttcatcc aacatttttc
     5941 cgattagaat aatagtggtt tggtcttttt gtcgagtggt gtattgaaaa ttaacctgtt
     6001 cgtttacctc ttgcatggca actataaaat cctgctcttg taaagcaatc aatcctttaa
     6061 aacgatacag gctcccttgg ttggttaaaa tcagccagtc aatccattgg agtaaaaaat
     6121 ctttttttat gtcttgatct gaagttaaga gaattgattt aaactcatgt acttgatggt
     6181 gttgatgata gtatttgcca ttatagtgat tttctgatga atcactttca aaaactaagg
     6241 gatgattaaa ttttttcaaa ttataaaaat cctttttttg aatcgtttca ctatgtgtga
     6301 acattcgaat atcggataaa gggttaatac ttttgatttc tctctgtaat ttttttagtg
     6361 cagataaatt caagttttgt tttctagaca caaaaatgcg atctgccatg acaagttgct
     6421 taagggcttg tggttctctt tcaataagtt caaaactgtc actatcaata acagtcaata
     6481 aactatcgat atatactctt cctcttagtt gaggcgctgt taaaagtgtt tgaatgattg
     6541 gttggggatc tgctatacct gtagtttcaa tgatgatttg tgaaattggt tgttgatgtt
     6601 cttctattgt ttccagtaaa gaaatcaata ttgctaataa atcactgcga agactgcaac
     6661 acatacatcc attatttagt tgtaacaccc gttcctcgct atgaactaat aatttgtgat
     6721 caatcccaac ttcaccaaac tcattttcaa ttataataat ttcttccctg gggtagggtg
     6781 agacttgcaa ggcttgattg attagcgttg tttttccagc ccctaaaaac ccagaaacga
     6841 ttgtaactgg tatgcccatt ttgtcacctt tttaccactt agctatttca cttctttaaa
     6901 aattgcccgt ctgcgcaatt ttggcgaata cttttttaat tctaaccgtt cagggttatt
     6961 ccgtttattt ttgctggtga gatacagacg ttctccagtt tcgacacatt ccaaaataat
     7021 attttgacgc ataaatcttc ctccttcaat acttatcgat cttcaagata tgcttgaatt
     7081 tgttgtgcat cttcaaaagt taactcgcca gattccaatt gtgaaactaa attttctttc
     7141 atatcaacag gtatctccca ataaccatcg atacattgaa ataactcctc gtcatactct
     7201 tcaaaaattg gatagattct taaaaaatca tcaaatgata agccttggtc ctcatagtaa
     7261 tctttgacta atccattttc aattgcctgt tgggtcggta aacccgtttc agtaataatt
     7321 cctctctcta ccatcgaacg ataaaaagtg catttatcta gcgattgctg ggtcgtttca
     7381 agataatact ttaatccttc ttcaactaaa ggtgggtaaa taatttccat tttgattccc
     7441 tcctaaaagt tatatattaa actattttga agctccttta attactttct ttccattata
     7501 gtaccctttt aaagatacat gatggctacg tctataatca ccattcgctt cgtcaaatga
     7561 aatttctggt tttactacag tttgatgagt tcttcttaac cgtttcttcg ccttagatgt
     7621 ttttcttgct ggtactgcca tgatatttcc tccttttacc aacttgcttt ttttactcca
     7681 ggaatcaacc cttgatgggc aagttctcta aacttaatac gggacatacc gaactttcgc
     7741 atataccctc ttggacgacc atccgtctga tcacgaagcc tcagacgatt cggatttgaa
     7801 tctcttggca atttagcgag agcggtgcga tctcctgcgg cttttaattc ctgacgttta
     7861 tctgcatact tttcaatcat cgccatttgt ttctttgctt tagcaatttt cgactttttt
     7921 gccatatacc tttatactcc ttttattttg atttagacac ctcaaatcgt aatcgttacg
     7981 ttttgacact gatactttac caacaagagt tgctcttgtc aacaataaat aacatgaaat
     8041 aaaactcata tgaatagata actatttgaa aacgaattta tcggtacata gagataatca
     8101 aatcatttaa aagaatatgc agtttaggct ctgaaaaata agaattcact tttattagtc
     8161 caatcaaaca caaataccgt tttaagtagc ttttcctcta cttaaaacgg caatatgaaa
     8221 gaaactataa ctttttattc aatcttttat gtttaactgg tttatcgcca attttttaaa
     8281 actttgatta ttccttatat tataagaata gacattaagt gaactaattc aatcatactg
     8341 attctttcgt gtattcaaaa ttagatgctg tttaataaaa ttattctttt tgaaaaagaa
     8401 ttataactat atcccaaaaa ttgtaggtta atttaaagcc tatttcatca tcgtgattga
     8461 gcttcttttt catagacgaa tttctcagat agtttagttt tctttatgag atttttgtat
     8521 atttctgacc ttcgatacaa ctcattatga gtaccttgat caactagttt tccttgatcc
     8581 atcactacaa ttttatttac cttttcaata gacttcaagc gatgcgatat aattagtact
     8641 gtcttatctt gtattaaacg atttaaactt tcctgaatac gtttttcatt ttccgcatct
     8701 aaactggcag taatttcatc taaaattaaa attggcgcat ttttcaaaaa agcccgtgct
     8761 atggataggc gttgtcgctc tcctccagaa agtgaacttc cgttttctcc gaccaatgta
     8821 tgataaccgt caggtagttt ttcaataaag tcttcgcagt tagctaaacg agctgctttt
     8881 ttcacttcct catctgacgc ttgactattt ccaatacgta tattttccaa aatacttgta
     8941 ttaaacaaag ttacctcttg aaaaacaata gcgattttgc taaacaaaga agctggagat
     9001 acacgtttaa tatcataccc atcaattaaa atacagcctt catcataatc atacagtcta
     9061 gacactaatt tcaagatact agttttcccg gaaccactag cacctactaa cgcagtcact
     9121 tctccttgtt tagccgtaaa agagatatga tctaaaattg gggtattgtt atcatatgag
     9181 aaagagacat ctcgcaactc aatgtcaaaa gatttcagag gactatctga tccctcttgg
     9241 atactggttt ccttcatagc tctaattcgc tgtattttag gagctaaata aaatatttca
     9301 agcactgctt ctttcataga atcgaaggaa tcctttattt ttattgcggc tagtaagtaa
     9361 ccaacgacgt agagtatagt cacttcaccc gttaacagta agtgaacacc tactagaatg
     9421 actactgcta aactaacata tgagaaaata gaggataagg ccatgactga aaaagtactt
     9481 aattctacct ttaaatgaat cctttcactc tcttccattt ttttgaaaag tctgtcttga
     9541 acttttttag atagattaaa gctattaatc tcttgctgca attctatagt ttcttgaaat
     9601 tcttccgagt tttctctcaa agtatcgtaa tatttagtat tggctttcgt ttgggatttc
     9661 tttgataaca agattaagac aaaactaaat aacgttggca aaataacagc taatcccatt
     9721 ttgacattac caaccaaaag catcactgaa ataaaaggga aaaacagagc cataccgccg
     9781 gctttaggta ttgcatgact catcgcatgc tcaatacctt caacgtcaga catgatagtt
     9841 tgagataaat ctgataaatt atgttttgaa aaataggata atggtaaatt tgacaaatcg
     9901 tctgcaattt gcactcttaa atgcgcactt tctttataag tactattata taagttttca
     9961 tactccctat ctaacaacca atacatgaaa agcaaagtaa caaacgatac ggcaaaataa
    10021 agccaacggg gctttgtatt ttctaaaact aattcgtcta tcagcatcat tataatgaat
    10081 gctggtacca tattaatgca gtatacaaaa aaactagaaa tagaagcttt agttaaagct
    10141 tctgcgccct gatcacttaa agcaaatttg tttttataaa aacttttcat tgtcaagcct
    10201 ccaatcattt gcattctcat aattagtgac caattgttta tacacttgat gtttagccat
    10261 taattcatta tgatttccac gttctactat tttcccttct gacaagacaa gaatttcatc
    10321 tacagattta atgctggata atcgatgagc tatcataata actgtttttt cttttatcag
    10381 atgttgaaaa gccttttgta gttcatactc attatctgga tcaatagatg cactggcttc
    10441 atccataata acaatctttg catcttttaa aattgctctg gcaatagcta tacgttgttt
    10501 ttctcctcct gacagataaa ctcctttact accaattaag gtatgctctc tttcgggaaa
    10561 tttttctaaa atcgattcgc aaccggctaa tcttagcgcg tcaaatactt tacttgctgg
    10621 cgcttgagga tttgctatag aaacgttatc gtaaatactc tgattgaata gtttcgtatc
    10681 ttgaaagaca aaagcaattg tgttaataat tgtgtctttt gaatagtgat ttaaaggctt
    10741 accaccaatt ttaatctgtc ccttatccac attgtagaaa cctgaaatta gtttagctat
    10801 cgtactcttt ccgcttcctg attttcctac taatgcataa attctttttt gttctaaaac
    10861 taagttgaaa ttttctaaaa cacactcttc tttgtatgaa aagctgacat tttcaaatgc
    10921 aatgtcacaa tttttaatct gtgtctcgtt cccatatttt agttggtctt gcttcatttc
    10981 taaataaagg gagtctagtg tttcgactgc atatcttgct tcaaacaagt gcatacttac
    11041 atacattatt ctcatgaaag aaacaaaaat aattccactt aaaaaaaaca acatcaacaa
    11101 gtcaacagct aatatcttgg gagtggtaag agaagttata aaaaaggtta taggaactat
    11161 caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga acaaaaggtg ttttcccact
    11221 caaagaatac ttatatgcaa acttagcata atcgttaatt gctttattca aggctttaaa
    11281 tgatgttact ttagcaccaa atatctttat aacttgaatt ccgcggatat attctaccgt
    11341 ttcagagctt aacacatcta acgattcttg atatttttga ataaaatttg tattctctgt
    11401 cattttcttt aacaagaata caccaattac taacatggcg attagaacca atccaatttt
    11461 aaagttaatg aaaaagccta aggcaactga taaaacaggt gttactatgg cttgagcact
    11521 atctggaatc aagtgagcaa ttgccatatg tgttttagcc gcgttgtcat caattgtctt
    11581 tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa cttgcttctg ttaaaccgct
    11641 aattcccttt tttctcaaat tagtctctaa gcgaaaccca aggatatgag aaaataagcc
    11701 agaaaaaata taaaataaag ctcctaaagt taaccaagca acagtttgaa ccgcataact
    11761 cttagctaaa tattcatctc ctacaataat tagagactga agaaatttgt aaatactgta
    11821 atatccatag actgttaata cgacagaaaa atcagaaaat aaagtggcta accatccgta
    11881 gtatttcatt ttagggacat aactaaataa ttttttgtat actttcattt tttcctcccc
    11941 cgcattcaat ttcttctctt attcgtttac aactgttaat gctttccgta atagcgtaaa
    12001 ttagagatgt acaaacagat aaaaggtaaa ctacgttcta ttttttgtat ttttttaaga
    12061 cttttcttcc aatcaataca ccaatcatag ataaacttgc tacaactaac actgaaatga
    12121 ttccccatat acctaccgca tagtggatca ttgcatccat tgttgcagca gattgtcctt
    12181 tatctatcca atcttgacga aaacgatctg taaagaacca tataggaatc cactgtccgg
    12241 cagcactgcc taattgcatt agagcccaag acgcaacttg aggaattgct cgatcatatc
    12301 caaatacaga tagaataata tcagctaaga tcgccatact aatcgaactg ataaaccaag
    12361 gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa aacaattgtg taaatagtaa
    12421 aaattccttt tctagggtag ttatagctaa tataaacaaa tatgattcca gataataatc
    12481 caaaaatccc gggggatatg ctgtgaccaa acgccccacc aatactacta accattattg
    12541 aaaaaaagta aattactagg gaaataactg tagctaaacc aataaaaata taatcttttg
    12601 ttttcatata tattctcctc aattctattt cgttatgtca ttaaaaatct gttctatcaa
    12661 agttgaatct tctactctaa gttttatatc tttttttatt ccaccatttt ttaaataaat
    12721 aattctattg catgttttat aaagaaattc cggatcatga gtagctataa ctactgcacc
    12781 cttttctttt aagtctttaa taaggtcagc aatcctttcc atattaatat aatccaaccc
    12841 acttgtaggt tcatcaaata gaaataaatt agtttttgac aatgaagcta tagaaaccaa
    12901 taatctttgt ttttctccac cggataaatc aaacggtaat tgatctttca ttttataaag
    12961 ttccattttt tttaaaattt tttcttgctg atctttacta actatttcat tccccagggc
    13021 taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc atttcttgca ttactaaaaa
    13081 cggcgatgac aaattttttt tattttcgat tatctttcct ttggtagggc gaataatctt
    13141 catgagtatt cttagtaagg ttgttttccc cacaccgttt ttccctacca aaccaataac
    13201 atctccaact ttgacatcaa aatttatgtc ttttagaata ttttcataag taatttcttc
    13261 aacttttaat acatctgcac ttaccttttc gatataggga acttcaatcg aactattaaa
    13321 aatgtcaaat ttccttaatg cgttattgtt ttcagttttt aacaactgaa tagttgtagt
    13381 ttttacagtt ctatttttaa caaatagaac ttgatcaatt aattctttca aatagtaaaa
    13441 acgatgttca gctataacaa tagtaaatcc tttatttttt aaatcacaaa gtaagtcagc
    13501 aagtttctta gtcgctttga agtccaaatt tgaagacggt tcatccaata taattaattt
    13561 agagtttagc gataaactac atccaataga aattttctgc cgttcaccac ttgatagcga
    13621 aaaaatgttt ttatctaata tatttgaaag atctaataat tcagctaatt cattgattct
    13681 tttatccata tgctcttttg taaatccaaa gttttccatc gaaaatacta actcactcgt
    13741 tgtatttgtt gtaaagaatt gtcctctagg atcttgactt acgtagccaa tattttttga
    13801 tatactttct tgtgttaagg attgtagcga gttattttca aataaaattt ccccaaccaa
    13861 ttttccgtca taaagtcttg gaataagtcc attcattaac tttaatagtg tggatttccc
    13921 actcccagaa gaaccagtaa tcaatgtaag actgcctttt tttattgaaa aattaaggtc
    13981 aacaagcgct tgttccttaa catccttata tgaaaaagaa acattgttaa attcaaacaa
    14041 ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt aacggaaaac aggatgatat
    14101 agtctaataa gctcatgttt gttttatagt aagaacttct tttcacagga gattctatcc
    14161 cctttgttat tgcattagcg gtcatttctt cagcaatcat agttgcacgt ataagaacgg
    14221 gaactaacag aaattccaaa tattgcagag gctgaaaaaa agacaagcga atgtttctca
    14281 tttttaaaga ttctttaatc attcttattt cagaacgata agtcggaaag aatctgatca
    14341 ctactgtaat acttaacatt atttttttcg gtaaatgtat tttttctaaa gaggataata
    14401 attcattgct agtatagaca ctaaccaaca accatgagat cattacgacc ggcaacattc
    14461 gaaatacaat atataaggat gtcgcaaaaa atatagtaaa aaactctatc ttgatagcat
    14521 caataatttt cattactaaa aacagaactg aataaatcaa gatgaaataa atacatgtct
    14581 ttattttacg aaacatcaat actaaaactg tagcaataat gaaacacccc acttgaaata
    14641 tatttccctt tcctaaaaaa ataatgaccg gaaaaaaaat atttaaagta atcaaggtta
    14701 acggattgat ttttgacact ctttcacctc caaaaaataa gatcgcactg ttatcttaag
    14761 ctgataaaaa tgcaccgtta ttcagataac agtgcgatct tatcaaaaag cataactgag
    14821 aacaattctc aatgcaagct ttttttaatt aactcagtaa ttcaatccac ccaggaacag
    14881 aaaattgata caatcttctg gttaatagca tagtcttttc ttttgaatag ctatgcttca
    14941 atatatcata gaatgtagcg tagaatgagt aaatgtagaa gtggatttct tcttcattaa
    15001 agactaaatt ttgattgatc attccgatag tctttaactt atctagacaa cagactgtct
    15061 ttttcgtcac aaatgatgta attttttcaa caatatcttg atatttggtt ccagctgatt
    15121 ggaataaaat caaatcgaat atacgtttat tctcaaaaat ataattaata aatggatcta
    15181 attcattgaa gttctctctc caacttttct ctatatctat attttctaag tttaagaggt
    15241 atttggtaaa ctcttcatta tacatattaa taagcgcatt aatatgcggc tgaataattt
    15301 cttcaaataa cgcttcctta gaagtaaaat gtttataaaa agcacccgta gttacgcctg
    15361 cggtcaggca cagttgcctt atcttagttt gctgaaatcc ttctttttca aaatggctta
    15421 gtccactttc tattaacttt tggtgagtta taatataatc tctggtttct atgggtactt
    15481 cctcctaata agatgaatta actttattat cttacacagg acttgaagtt tcaatcgtta
    15541 acgtttatta ctgaactcat tccttagagc taaactaatg agaaagagca gaataactga
    15601 tacaaaaagc aatcctacaa gaattaatag actcatctaa atcattcacc ttttctaaaa
    15661 taatccgaga aagatttaaa aaaattatat ccagctatta ggataagtcc tatcataatc
    15721 actccaatag ccattttctt atcctcccta aaaataaagt cttttactta aaaccttttt
    15781 tgtaatcgtc aataaatttt ttccctttat cagttaattg aaatcctata tctaaatagt
    15841 cctcatatct aagtttagcc agcatctcac ttacagatgc tggactaaca cttagaactt
    15901 ttgctaaatc attatttttt aatttctttt ttctttttga taattcctga attgctagta
    15961 aataaattag tatagtagtc gttttaattt gtaccatacc taccctccaa attatttcga
    16021 aaggccttca gcaattttat ccaggttcca tttcatcatc gcatagtaac tatcaccatc
    16081 ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa tagataggaa tattggtatc
    16141 ttttgatact gttttcattg gtctatcatc cacactgctt tctacgaata aggagggaac
    16201 ttttgttgtg cgtaattttt caactaagtg ttttatttga tctggtgttc cttcttcttc
    16261 agtgttgatt tcccaaatgt aagcagaagg cacattatac gctttcgaga aatatttaaa
    16321 gcatccttca cttgtaacaa tcattttttt atcattcgga attgaagcaa atttagattt
    16381 agcttctttg tctagagaat ccaatttttc aatatactta tctagatttt ctttatagaa
    16441 ttttttatta tcaggatctt tttccgctaa ctgtttttca atatttttag cgtaaataat
    16501 accgttttct aaatttaacc aagcatgagg atcttccttc cctttctcac tctgaccctc
    16561 taagtaaata acatctatgc catcacttgc tgcaaaatag tctttgtttt cctctttgtt
    16621 cgcattttta actaattttg taaaccaagc atttcctcca gtttccaagt taacaccgtt
    16681 ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct tcaggcaaag gttcatattc
    16741 gtggggatct ttcccaatag gtacgatact gtgtaaatca attttatctt ttgctatatt
    16801 ttcggtaata tctgctaaaa tcgaattagt aactactact tttaattttt cgttcgaagc
    16861 cactttatct ttgtctttac tatttattga acatgccccg aatataaaaa gagcaatcaa
    16921 aatccccaga cttcccagta ctgctttcca ttttctcatc ataacgatct ctccttcttt
    16981 cttaaaaatt tttgttttgg tgagattaga aaactaatta caaataagaa tgccgctgtt
    17041 aaaacaatac ttgatcctgc tgctatgtta aaactataac caataaacaa tccaagcaat
    17101 gatgaacttg ctccgactgt tgcagaaata aatatcatag ttttcaagct atttgcatat
    17161 aaatatgctg tagctgctgg tgtaattaac attgcaacaa ttaatatagt tcccacactt
    17221 tgcatagctg ttactgctac taaagttaat agaaccatca atagataatg ataaaaactg
    17281 acattcatcc ctattgcttt tgccattaat ggatcaaaag aagtgattaa taattcttta
    17341 aaaaatagaa ctactataac caacactaaa accgaaacgc caattgtaat ccacttatca
    17401 atatcttgta cagctaaaat atttccaaat aaaatatgaa ataaatccgt tgagctattt
    17461 gcaactccta taaggataac tcctagtgct aaaaaagaac tgaaagtaat accaattgct
    17521 gtatctcctt ttattacact attgcttttt ataaaagtaa taatgataga agctaataga
    17581 ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa tataagaaat tgctactcct
    17641 ggcaaaacag catgagaaat agcatcaccc ataagagaca ttcctcttaa aataataaaa
    17701 caacctactg ttccagaaac aatccctata actacagatg taattagagc attctgtaaa
    17761 aagtgaaagt catacagacc attaataaaa ttttgaagca tattattccc cctctccaat
    17821 aaatatagta tctccatagg ctttttttaa attttcttca ttaaatacag attctacact
    17881 tccgtgagca attagatttc gattcaaaag aataatatta tcaaaatact tctttacctt
    17941 gcttaaatca tgatgcacaa ttagcactgt ttttccctga tgtttcaatt tttttaacgt
    18001 atccataatt attcgttcac taactaagtc tatccctaca aatggttcat ctaaaaatat
    18061 gaaatccgca ttttgagcaa gacatcttgc taaaagtaca cgttgaaatt gtcctccaga
    18121 taattctcct atttgatgat tagaatattt tcccatatcg accttttcca aagcctttga
    18181 aactctttgc cattctgcat ttttaattct ttgaaaaact ttcattccgg catatgttcc
    18241 catagataca cattctttta cttttattgg aaaagtaaaa tcaatatcag ctttttgctc
    18301 tacatatgca atcttcacca gttttttatt gatatcttca ttattaatgg agacctctcc
    18361 ctgatgaggg ataatattta acattgcttt aagcaatgtg gattttccag caccatttgg
    18421 accaataata cctgttaaag caccttcttg tatttttaaa gaaatctcgt tcaatgctaa
    18481 aaaatcgtta taacaaacat taagcttttt cacttctaac ataactttct ccttctaaat
    18541 gataatgatt atcacgatca tatggtatac aaaaattata ttttagtcaa ccctaaattt
    18601 tatagtttag atttttttct gttgctgaag attagaatga caaaactatt tgaaactacg
    18661 cgtatagtaa gtagctttca aaatatataa aaaaggagcg ttctcaaatg agaacatgct
    18721 cctaaaacta ctttattggc gtatggaaaa attatacttg aagtggatag cgggttgaat
    18781 aagttgataa gcatcaaaac atttataaaa attattcaag actatgtctg ttccatatac
    18841 aaatatgaaa atcagtaaac tccatttaac ttttttcgta gtgtgtcttt ttatacatgt
    18901 ttatcgttat taatagtgaa taggaaaaaa actatttttg atcattgaca attaaataca
    18961 atttttgaat aacgatccct gctattcgag ctagaaactc aagtacgcca tgacctgatt
    19021 agcgacaaat acttagagat ttctttttgt tctgggaaaa caaaatgcca tgacaatagc
    19081 agcaaataat gatacttccg taaggctcgc cgtaaactgg ggagaggtga aattcctatg
    19141 tgcttaccca aagcaattca aaaatttcat aactactatt ttaggagatg attttataga
    19201 atccagagtc tacctgaata aaaaacaaac ctgtgcattt ctaggaatcg ataataatac
    19261 tctagataag tggattcgta tatataattt cccagtaata agagttggtg gtgtagttcg
    19321 ctttgacgta gaagatatta aagactttat gaatacattt aaaataactt gaaattttct
    19381 tctcgccgca tatactaaaa ttagtgaaat atactgcctt acttttttta aggagtgagg
    19441 attttgccta caaagctttc aaatgggaaa tataaaacta atctgagata tccaaaaagg
    19501 tttaaagaaa taacaggaat tgcatcagaa aagtatcaaa aaacatttcc aaataggcaa
    19561 ttggcgatta aagccgaaaa tgatatgaag aagaaaatag aaaaagtttt gagagaggag
    19621 aatgcaaact cattagaatt aaaaggaaaa ataacgttta aaaaatttta cgaatctaaa
    19681 tggcttccta gatatgaatt aggtcaaaca attagatcaa acaggcctcc tagtgatata
    19741 accattagta atacaaaaga tatatttcgg ttgcatattt tacctatgtt tggtgaatac
    19801 gcaatgaatt atctaaatat caatactgag ataatatcag atgaattaac caaaaaatcg
    19861 aaagaatatg caaatataaa aatcataaaa ggatatgttc gttccatgtt cgatattgca
    19921 gaaatactaa attatatcga atttaatcga actactaaaa ttattcaaag tatcactgca
    19981 cctaaaaaaa atgctttaga agaaaaaaga atacaagaag gtaagcaagc actatcatca
    20041 aaagaactta ctaattggat agaagcagta aatgatgatt ttaataatca tttacttact
    20101 tttcatgatt acacactttt tatgattacc ctgtatcttg gtgatagaaa aagtgagact
    20161 tacgctttgc aatggaaata tattgatttt gaaaaacaaa cggtccgtct taaacatact
    20221 ttagataaat atcaaagaaa aaagtttaca aaaggtcgaa aagataccgt cattcaagta
    20281 ccagaagttg taatgacatt gctaagtgaa tggaaatcgg tacaagctga tcaattgttg
    20341 aaattaaaaa ttaagcaaac gttagatcag tatctcttta cttatactaa accatctgga
    20401 gaagtaaatt gtcctgttca tgccgattac ctaaactatc gaatcaattc aattaaaaga
    20461 aggcatcctg acttagttca tttatctcca cacaaactcc gtcatactta tgaaactata
    20521 gctagacaag gtggagcaga tatgaatcaa atttcaaatg ctttaacaca ctcagatatt
    20581 tctacaacaa agatatatgt gaacacacca gatatagttg ataaggctgt ttttgaagct
    20641 tttcagagag gattgaataa gtgtgattga tatgtgttct taaatgtgtt cttaaaaaca
    20701 aaagaagcac tttccaaata attgaaaagt gccagaaacg ttgatatata aaggatatta
    20761 acgttttgag aattgtgaag ctttacgtgc tttcttaaga cctggttttt tacgttcgac
    20821 catacgtgcg tcacgagtaa gtaagccagc acgtttaaga gctaaacgga agtcaggatc
    20881 aacttctagc aatgcacgag cgataccatg acggatagct cctgattgtc cagcgtatcc
    20941 tccgccgttt acgttaacaa atacgtcata tgcgcctttt gtttcagtaa cagcgaaagg
    21001 ttgattgatt acttcacgca agtcagcatg tggaatgtat tcttcaacat cttttttatt
    21061 tacagtaatt ttgccagttc ctggtactag acgtacgcga gcaactgcgt ttttacgacg
    21121 gcctgtgccg atatattgaa cttgtgccaa tgaaattccc tcctattaga ttaagtttgt
    21181 gatgtctaaa acttctggtt gttgtgctgc atgtggatgt tctgctccac cgtatacgtt
    21241 caattttgta aattgtttgc ggcctaaagt gtttttagga agcatacctt ttacagaagt
    21301 ttcgatcaaa cgacgagaat ttttagcacg caattcgcca gcagtgattg atttcaatcc
    21361 tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc gcttttttac ctgttaattt
    21421 cactttgtct gcattgatga cgatgacgaa atcgccagta tccaaatgag gtgtgaaagt
    21481 tggtttattt ttaccacgta gtacagatgc aacaactgtt gaaagacgtc ccaatggaac
    21541 atcagttgcg tctactacat accatttacg ttctacttcg cctggtttgg ccatatatgt
    21601 tgtacgcacg ttattttcct ccaatttaag ttctgatgtt tgacatacac ttcgagtttc
    21661 cggggctctt tgtggggcaa acaataccat ttaacatatt acccgctaat ctagtcaatg
    21721 tcaacgtttt tctgcttgat tgaaaaattt atatgaaact ttacttcttt tctttctttt
    21781 atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa gaggctgtga caaaagtctt
    21841 gtcacaaccc cttattttga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca
    21901 caatatccat aaaacataag aagctgtttt ttaaaattgt ttcttgtgac tcggagctga
    21961 acggcaggct tacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
    22021 caaaaaacgg caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa
    22081 aacgctgatt tcacaacctc tttttcggtc aagttcaaca acagttttta cgcgtcgatc
    22141 tctggcgctt tgcccaaatg agcttggatc atccagatac gtttttctgt ggctgttttg
    22201 aattcgataa agatatcttg tgttggatcg tcgccttctt ctccagaaac ttcgattcct
    22261 ttttggtaaa gatctgctag ataacgatag cctgcaacaa gtgtttccaa acgttctgga
    22321 atagtacgat cccagcggcc aatttcatca gggatttttg tgttatctgc aaattcacgc
    22381 aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt cggatacttc atctaactga
    22441 gcgttcaaat catccatgaa ctcatccatc attgggtgca atgtaaggaa acctggtcct
    22501 ctcatgtacc aatgtgtttg gtgaacaaca acagacattt ggcttagatc tgcaactaat
    22561 tgatttaata cttctttggt ttgttggaat ttcatctttc ttgcctccta acattttctt
    22621 acacttaaaa taatagtaga ctttcaatga aaagtacaac aaaatcattt acctgagaac
    22681 gattttcagt tcgctttttt atccgtaaag ccaatcattt ttcagaatca gctaattctt
    22741 ctcgcagttg agcaaattgc tgataagtct gtgctaaatg cttttgtgtc gaaacaaata
    22801 atggatagat tttctgatat tttttatgat cagtttcttg tactccaact tgctctttca
    22861 attctatcaa ttcctgtgct tcactgatac tttggatctt tccgatgctt ctccagccta
    22921 aaatcacagc tcctaatgcg gatgcttctg tgacagtagg gaaaacaagc gggtaaccca
    22981 gtacatcagc catcatctga cgaaaaatcg gagattgagc aaacccgcct gtagcacgga
    23041 tctctgtgag ctgattttcc tggcaaactc cttttaaaat ccgataaagg ttgagacaga
    23101 tcccttctag aatcgccttc atcatttctt tttctgtatg ttgccgctgt aaaccgataa
    23161 aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc accaagtaaa tagggatgaa
    23221 aaatcagacc attggcaccc gctggcacaa aagcgatagc cgaaagcagt gcatcatatg
    23281 gattttctcc tttttcttta gcagattgaa cgacttcctg taaaaatgta tgccctgccc
    23341 aatcaaagat gccagcacca ttgctagtcg ctcctcccac tacccaatgt ttctgatcca
    23401 gaacataaca aaacgtctcc atttctggat ggaactgagg ctgagtagta ataaaacgaa
    23461 gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc accaaaagca cctaacccta
    23521 gattagaaag cggcccgtct gcccctccca aaacaaatga tatatcattt ggcaaaccta
    23581 gttctgctgc tgtttttgat ggtagacctg ttacttgata ggtggaagga aagacttgcg
    23641 gcaattgctc tattcgaatg ttcaagtagt caagcacttc ttctgcccat tggaattcat
    23701 ggatatcaaa atatccagtt cctgaagctg ttccgtagtc gctgatcagt tcgccaaaca
    23761 atctataaaa gatatagtct ttgataccga caaaataagc agtttttttg aataattcag
    23821 gttggctgtt ttgcagccac ttgattttgt tcaatggtgt cattggatga atcggcgtcc
    23881 cagtctgccg ataaaattct ttgccaagca cggtatattt cagtttttct gcttcgtccg
    23941 ctgctcggtt atctgcccaa gtgatcattc gagataacgg tgttttctct tcatccaaca
    24001 atatcaggcc atgcatcgca gaggagaagg agacaaattg aatgattgtg tctgaaggca
    24061 actgtttaat tacttctttt ataacggtgc agacaccttg aaagatcaat tcctgatctt
    24121 gttctgccat cccttgtgtt tcttggatca aagggtagcg aaaataagcg gatgctgctt
    24181 cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt ggttccgata tctaatccga
    24241 ttgaaacgtt cattttttca cctcaaattt tatgtatgta caaaaattta gtttaagctt
    24301 gcgtatcttg gttttgaaaa gggggagatg gcgtgttact ttattttatc attggttgct
    24361 gtatcggatc atttttatgt ttaaccgccc agcggattcc gttaggtcac tctattattt
    24421 atcctagatc tcattgtgtc aaatgctgtc gttcgctttc ttggtatgaa ttgattccga
    24481 ttctctcgat catcgtccaa cgatttcgct gccgctattg caggtgtcgg ttgcccttct
    24541 actatttgtt ggcagaagcc ttatgtggtg gtctttttgc ctggttcttt actttttctt
    24601 ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc tttgctattt tcgttgatgg
    24661 atttatttta cttcatggtc cattctcaca cgctattctg ttcttgggca attttatgga
    24721 ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt gctgttaacg tttatcgtag
    24781 gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc tggcgatact ctgttgatgc
    24841 tttcttggag tggtggcttg tctctagaag agttgcttca gatcttgttt cttgctagtc
    24901 tgtttggaat atccgttttt tctgtttact ttatctgtca taaaaaaaag ttggaaaagc
    24961 tgcctttcat tccttttttg agcagtgcgt tgctgattgt ccttcatctt aggtattgaa
    25021 aaaaggttgt gacaaacgac ttgtcacaac ctctgatata tagtgttctc ttaccaaatc
    25081 cttgtgactt ggagctaggc gacaggttca caacctctcc actaaatggt gttcaatcag
    25141 ctgaccctca gtattagctc aaaatgctgg ttttacaacc tctgatatac ggtgttccat
    25201 aagtagcttt ttcggcttct tatttcttga cgccccaatg tcgacgaagg aaacctgcac
    25261 gtccagaacc ttctcgataa agattgtaat ggagcttgtt tttcttgtaa taatcctgat
    25321 ggtaatcttc tgcaggataa aattcgcttc ttggttcgat ttttgtcacg attggcttat
    25381 cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc tgcaatattt cgttcttctt
    25441 catcattata gtagatcact ggacgataag aatcaccgcg atcagcgaac tgtcctaatg
    25501 cgtcagtcgg atcggtttgc tgccaataga tttccaccaa ctgatcataa gaaataactt
    25561 ctggatcata ttcgatctct actgcttctg tatgccctgt tgtgcctgtt gttacttgtt
    25621 cataagttgg atttggtaca tgcccgccag tataaccgga tgtcacagaa atgatccctg
    25681 gctgctcttc aaatggtttg accatacacc aaaagcatcc gcctgcgaaa actgcttttt
    25741 ttgtcatata aaatccccct tttttctcat cataccttga tttccaaaag gaggataacg
    25801 ttttgcttgt gacagaaaaa acggaaacta ttatatacgt gatacggctt ctgataaatg
    25861 ccaaaacgaa cgtacttgat caaaaacggt taaatcagga atcacatatt cagcagaagg
    25921 aagatttatg ttttcaccta ttcccaatac atgcatgtta ccagccaaag ctgcttgaca
    25981 accagcttct gaatcttcaa tgaccaagca tgcatttggc ggtacattca attgctgtgc
    26041 tcctttgaga aaaacttctg gatcaggttt tgcttttgat acttgcgtgc cgtcaataag
    26101 gacatcaaaa taacttgtca aattcgtttt ttctaaaatg aggcgtgcat ttttgcttgc
    26161 tgatcccaat ccgatcttga tgtttgtttt tttcaagtac tcaagaacag ctattgcacc
    26221 aggcaaaacg gatgtttcat ccattttttg aatcgcttga agatatagat tgtttttttg
    26281 ctcagcaaag gctgatttct ctttttctga gaatttctgt tccatttttc caaatgacag
    26341 caatcgctct agtgactcgg ttctggatat tcctttcagt tgctcgtttt ctttctcagt
    26401 gaatggaatg gacagctggt tagctaaaac cagccacgct tcgtaatgat aacgagctgt
    26461 gtctacaaga acgccatcta aatcgaatag tgctgctttg attttcatcg attacctcct
    26521 tgaaaatgaa cgacttgaag taaagatgcg atgtttttag ctgtgcgatg aagattatca
    26581 gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag gaaggatcgg aaaaacggcc
    26641 gaaatgccaa catctgctgc tttttcgctt cctttaccaa cacttccgca aatagctatc
    26701 acaggaacgc cctctggtac tcttctagca atcccaactg gcgcttttcc ttttagactt
    26761 tgtccatcta gacgtccttc gcctacgatt acgaggtctg cttgctgtac ccgtttatcg
    26821 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
    26881 aacagtcctg cacccattcc accaccagca ctactgcccg atgcctcgat tacttgaggg
    26941 gcaaatctca tataaaaatc atgcatggct tggtcagcca ctgctaattc attttctttc
    27001 aagccttttt gtggtccgaa aacaaaagaa gcgccttctt ttccgcataa aagattagta
    27061 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
    27121 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
    27181 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
    27241 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
    27301 actcctcgcg tggataacct aagtggctgt tgttggttta gtgggacatc tttcaatccg
    27361 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
    27421 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
    27481 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
    27541 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
    27601 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
    27661 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
    27721 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
    27781 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
    27841 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
    27901 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
    27961 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
    28021 gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt ttcatagtaa tgcaaattct
    28081 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
    28141 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
    28201 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
    28261 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
    28321 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
    28381 tataatgcgc cagatagttc gtatatgcat tattgtcgat atattctgtg tattcatctg
    28441 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
    28501 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
    28561 ttgcttggac atactcttga acggcataag caaggtctgc actgatatga tgttctgcgg
    28621 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
    28681 tctcttcctg accagtgtgt gcgctttccc atgggaaaag tgcaccttga tagtgataat
    28741 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
    28801 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
    28861 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
    28921 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
    28981 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
    29041 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
    29101 acgggtctgt ttgctgaaga gaggtagaga gcacgatgat cttctccagc gtaaaggacg
    29161 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
    29221 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
    29281 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
    29341 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
    29401 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
    29461 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
    29521 gctctcccat ttctaaatct agtgcccgct cgtatgcaag aactttcatc gtctcaagag
    29581 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
    29641 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
    29701 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
    29761 tctgactcgc atacttattg atatactcta aatcaaactg tttttcttct actttcataa
    29821 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tctggatgac
    29881 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
    29941 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
    30001 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
    30061 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
    30121 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
    30181 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
    30241 gtacgcccga acgcttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
    30301 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
    30361 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
    30421 aacatcaaga tgattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
    30481 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
    30541 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
    30601 ttcgaagtga aagcgattgg gtgtacagac actcacgata tcgggagaaa tctcattcag
    30661 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    30721 tcgctggctg actggatcaa ccacagcggc caattctaag acatctgatc ttttttgata
    30781 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    30841 ttatttctcc ctcctttgct tatttactta ttgttattct ttctctattc tttctctaaa
    30901 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    30961 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    31021 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    31081 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    31141 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    31201 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    31261 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    31321 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    31381 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    31441 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    31501 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    31561 gtttctttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    31621 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    31681 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tcctcggact tgaacgccca
    31741 ttttgatact ttcttctggg tgctggtcta cataacgcat gtaagcttct gcgctttctg
    31801 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    31861 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    31921 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    31981 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    32041 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    32101 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    32161 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    32221 cgatggtagt agcacctgct tttttagcta attgaatcgc aatttgcccg atagcgccta
    32281 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttcccggata ccacctaaag
    32341 cgaattgagc aggatcgtaa catactgcat ttttccattg atccaaccga tcaagtttac
    32401 gtagtttata attatcaaca ccgtttgtaa tcagcgtttc acgaatgggt ccataagtgc
    32461 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    32521 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    32581 ttggcaagaa taggcgccat tcttctgaaa attcttcatc gataaatgga cttaatcctc
    32641 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    32701 cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    32761 caactaattt tttcatcttt tctttcctct ttcttttctt tttatccttt tacgccgcct
    32821 tcgactaaat cacctttaat aaatcgttca gataacgcat acataatgat gactggtaaa
    32881 gcggtcacca atgaagcggc catcattcgt ccccaaatgt agtctggtgt actgaataat
    32941 gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg acaggaaaat cgaagcaaat
    33001 aaataatcat tccacgaaac cataaagcaa taaacgaaga cagaaatgat tccagaaata
    33061 gccaatggta taatgatccg aataatgatc tggatccggc taagaccatc gatcattgct
    33121 gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt ttagcatgaa tatcgcagta
    33181 ggaagtgttt gaacgaccat cgtgataatc agtgctgtat tggtatcata caaacctaga
    33241 ccggaaatga ttttaaataa tggaacaacg atcaaaatac cggaaaacat ataaacggtg
    33301 taaaagctag cattgatttt cgagcgagct ttgaagcgta gttttgacaa agcgtatgcc
    33361 ccgctgatcc caatcactac tgcagttacg gaggctatca aggagatcac taaactattt
    33421 ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa tatcctgata atgttcaaaa
    33481 gtccattctt tcggaaaaat agtttgtgtc gttgcaattg cttcttgtga atccttgaat
    33541 gatgtcatca gcatgatcaa aaatggaaac aaattgacag ctaatagcaa caaaatcgtc
    33601 gcgtaaaata agattttcct gctcttttta tttttcattt caagtccacc ttctttcgtg
    33661 agagcaagac gaccgctgca ataatgatga acaatagaat cgatatagct gctgcttttc
    33721 caagatcatt gaacgcaaag gctgtctgat acaaataaac gcctaagata ttgactttat
    33781 tcgtcagtag atagacatct gtaaacatat agaacatcca gatagatcgt aaaacaatca
    33841 cagttgctag tactggtttg attgccggca gtgtcacgat cttgaacttc tgccaagcat
    33901 ttgcaccgtc catttcagct gcttcataaa gcgttttgtc gactgtttgc aaaatagcca
    33961 aaaatgaaat aaacgcatac ggatagtatc tccagatagc aaacaaaacg accataaaga
    34021 agctagcaac tggctggtcg aaccacagcg gtgcttcgtt gaaaagctgc aacctatcta
    34081 ctaacagatc attgacgatt ccataactat tattgaacat atatttccaa gcaaaaatca
    34141 aagaaataga tggcgtaaca taacttaata aaatcagtga acgcaccgtt ttcctaaatc
    34201 tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa agctgtactg cctgctacaa
    34261 ctaagaatgt gtaagcaact gttaaaccta aagaacgata aaattcacta tcacttaaaa
    34321 tttcaagata attgcttaat ccgataaaaa cggcgtctga gttaggattc agcggcatat
    34381 cgaaaaaact gatctgaata ttggaaagca ttggaatcag cactaaaaca gctaataaaa
    34441 gcatgcttgg tgctaaaagt cccatggcta attttaagtc agaatgtttc cttggacgat
    34501 tcattgaaac ctccccctga taatctgcca atagctatct acttttttcg aacaccattg
    34561 gcagaacttc ttgttatttc gtattttttt gtgcgtcagc taaagcttga tcgacatctt
    34621 cgtttccgac agttacttgg ttcactgctt ttccgatcac acctgagctt gtgatatctc
    34681 ccattttcgt gaaattcttt tccccgacta gtccaaagac ttgtacttca tcaaaagcac
    34741 tagcaatctc agatggcagc tcgccaaaag acttgatgac ttcattttct ttgtaaccat
    34801 ccagttcgac tacttgttta ttcactggtt gagcaccacc aggagacatc aagacccact
    34861 tttccatgtt tttcggttga gataagaaag ctgtgaatgc ttcagcagcc tctttttgtt
    34921 tctcgtctag accagaagaa atcgtcaatc cagatactgt gccatagaca gcttgatctt
    34981 tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc cgcttcataa acagaaggca
    35041 aaatgtaagt tgaatagatt gccattggtg ctgttccatt catgaaagca tctttgattt
    35101 ctgtcacatc attagagcct ggcatcgtgt attgggataa gttttgataa aacgacaatg
    35161 cttctctcat cttttccgta tcgatcgtta cctcgccttc atcatccaaa acatttgctc
    35221 catttgacaa agcaaattga gagaacgctt gctcactcat tgttccttca gcagtaggca
    35281 tagcaattcc atattgttta ttctctttat ctgtgaaatg ttgagcaatt tttaaaatat
    35341 catcccaatt ttctggttct gaaaaaccag cttctgataa tttttctttg tcataccaaa
    35401 taccttgaac ccagccgcta attggtgcag caatatagct ttttccatct tctgaacgaa
    35461 caaggttttt ggctccgtca taataattat cttctccagc ttcctcgata acgttttgga
    35521 ctgccgtctg atcaatcagt tcatctttat ccatcacttt agcaaaatcc tgactgactt
    35581 ccattacttc tggtaattta ccggaacgag ctaacgtaac gatttttgta ttgaacgctg
    35641 attcttctac cggcacttgc ttgattttga tgtctggatt ttctttttca aaatcagcaa
    35701 ccagttcatt gatcacactt aatcgttcct gttcgacaga agagtgcatg aattgaatcg
    35761 ttgtctgttg tgattcgtta gagctttgac tttcaccaca agcagtaaga agaaatccag
    35821 tagctagcag acaggtagta acaataattt ttttcatttt tttccacctc ttattttatt
    35881 attttcagcc acatatattc atacggctgg aatatcaact ttcgttcttg actgcaatgg
    35941 ataatttgtc cagaaaacag gtctaggtaa tctccttttg gtaaaagata acctgctgat
    36001 tgattggaaa aattatggat aactaagact ttctcttcct tcgcttcgcg aataaaactg
    36061 ataaaagaat ctgctgagtc cagtaagtaa atcaaactat tcggatggaa ggctttttct
    36121 ttttttcgaa tagatagcat ctgggtcaat tcaccatata ctgctgttct taatggatct
    36181 gtctgcaact ctttctcaat atctgctaac aaaaattttt gccgattgat ttttcgattc
    36241 tctcctgttt tttctacgcc tttgtaatca tttcgacttc ccagcacact ttgaatataa
    36301 attgccggca cgcctggtaa cgttaccaaa aatgaatgag cagctaaaaa gcgtttgctt
    36361 ctccattccg tcgtatctgt tggagaactt aacgcatcta gatacgtagc gtttatctca
    36421 tatggactgg tcgttccatc tgggtttttc ttgtagttta ctcgggcacc ctctttcttc
    36481 agctgttcca ctaattcaag gatcgttttt tccggcagaa tacctcgtac cggattcaat
    36541 ccgataccgt catgggaggc taaaaaatta aaaaaagttg tttttttcga tgcgaaatcg
    36601 atggttttta accattcttt caacttactt gtattacccg aacgaatcgc ttgaagggtc
    36661 aaaggtggta gcgaaaactg atagaccatc tgtgcttcat tctcgccatt cccaaaataa
    36721 ctgatattat ctttgtgtgg cacatttgtc tcagtgatca ataccgttcc tggagctgct
    36781 tcatcagcga ttgcacggaa taattggatg attttatgcg tttctggcag gtgtatacaa
    36841 gaagttccta gttctttcca taaaaatccc acagcgtcca agcgaataaa tgaagcgcct
    36901 ttttctaagt aaaacaaaag aatatcgatc attttcaata aaacttctgg atttttaaaa
    36961 ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt gtttttcttt cccgtttttg
    37021 tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag tcacgctgct tgtatctgta
    37081 tccagtggca aatcaataaa aaaatctttg tacgtatcat tcaagtttaa atattcctga
    37141 aaccaagtac tttcggcaga catatgattg cagacaaagt cgaacattaa ccgtgtttcg
    37201 cttctcattt cttctatatc ttcccatgtg cccaaacggt cgttgattgc ctgataattt
    37261 acaacggaga aaccatcatc agatgtatat gggaaaaatg gcaagaaatg tacaactcta
    37321 aatgtatctg ccaaatactt ttgataaaat ttcttaaatg tacgcaaagt tggttgctgc
    37381 tcttcaaaaa attgatcccc ataagtaatc aagaaaatat cttcttcgtc ccaatgcagt
    37441 ttgcctgcct ggcctttctt ctgctgataa acactgactt tttgttcaat catagaggcg
    37501 gttttctcag acaaatctga gtcgcgataa atcgcttgta aaagttttgt atacatcgga
    37561 ttcccctttc ttttttggga gcgttcccaa cgatttgatc atattatgga aaacgcttac
    37621 tgtcaatagc atttttttaa ataattttga tatacacaaa aatacaaata agaaagctta
    37681 tgtatcaata attaatagct tcttaaaaaa atatggtctc tcatgatcat gcaagctatt
    37741 cctaaatttt caaaatcata gacaaaaaag aatgtctatt gtactatgga attattctaa
    37801 aacgctccca aaaaggaggt gcatataaaa ttgaaaccta ctatttatga cattgcgaaa
    37861 aaagctaatg tctcaaaatc aactgtctcc agagtattaa ataaccagcc aaatatctct
    37921 gataaagcaa aagcaagtgt acttcaagca atcaaagaat tgaattatga accgagcaaa
    37981 attgcaagag gactgtcagg aaatggtttt gacgcgattc tagcattatc tcatcgtact
    38041 tctcatacga cctatggcaa tccttttttt tcagatgtta ttcaatccat ttctgccgtt
    38101 tctgaacaaa ataacttcga cttgattcta caaacggcaa aaacaccaga agaagagcta
    38161 gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag gaattattat tttaagctct
    38221 acgatggatg aaacacttct ttttgaattg gatcaataca atattcctat tgtggtaatc
    38281 ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg acacggataa tttccaggat
    38341 agttacgatt tggtggaaac actgatcaag aatggacacc gtcatatcgg ctgtctccat
    38401 gctccgacag aagtttatgt atccaatgat cgtctcaatg gttaccgtca atgcttattt
    38461 gatcaccacc tagatatccg taatgaatgg attatagacg gcggctttcg cttagaagat
    38521 agcatggcag caatgaatga tttaatgaag ctacgagaaa gaccaactgc gattttttct
    38581 accgatgcat taaaatcatt gagtatttac aaagtggcag aacaatctgg aaagcagata
    38641 cctgatgatc tttcgatcgc aggattcagt gatcccttat tgtcctccct attttcgcca
    38701 cagttgactc ggatagacat tccgacaaat cagttaggaa tcaaagccac agaactttta
    38761 ttccaactaa tccaccacca ataccctgaa gaaaaaagaa tcattctttc aaccgagatt
    38821 actctcacag attcgatcca acaacaagaa atgtagaaca gaattataaa agaacagaaa
    38881 cactgaggat aagtcagtta ctctgttctt ttttcaatca ctcatccctc gttaccccct
    38941 cccggtattt tagcgaattt ttcttatttt ccatctgttt tagatagctg tggataacta
    39001 taatgtttgt gttaaactat tttttccaca gggaagaaaa aactattttt aaccacgttg
    39061 tgtataagtt tttatagttc gtttttttaa acacatttac ccttatttca atccatgtta
    39121 tttggggata cttatctcta aaacataaat agaataacag acatgtctac tggttttgtt
    39181 ttattcgagg aattattcaa taatagctag caaaatatta aaaataaccg ctctatcttc
    39241 ccatcaattt attttgcatt caaaaaatga tctatcttta cttttgttga ttgacttctc
    39301 ttggaagatg atcgttccga taccttaatt ggatacgaac cgatgttgtt aagatccttt
    39361 cccacttttc ttctagttag acaaattatt ttagacaaac caaaaaagag gttgtgacaa
    39421 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
    39481 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
    39541 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
    39601 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
    39661 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
    39721 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
    39781 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
    39841 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
    39901 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
    39961 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
    40021 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
    40081 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
    40141 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
    40201 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
    40261 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
    40321 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
    40381 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
    40441 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
    40501 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
    40561 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
    40621 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
    40681 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
    40741 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
    40801 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
    40861 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
    40921 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
    40981 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
    41041 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
    41101 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
    41161 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tcttttactt tgaatcgttt
    41221 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
    41281 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
    41341 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
    41401 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
    41461 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
    41521 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
    41581 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
    41641 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
    41701 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
    41761 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
    41821 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
    41881 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
    41941 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
    42001 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
    42061 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
    42121 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
    42181 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
    42241 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
    42301 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
    42361 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
    42421 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
    42481 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
    42541 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
    42601 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
    42661 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
    42721 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
    42781 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
    42841 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
    42901 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
    42961 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
    43021 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
    43081 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
    43141 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
    43201 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
    43261 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
    43321 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
    43381 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
    43441 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
    43501 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
    43561 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
    43621 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
    43681 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
    43741 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
    43801 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
    43861 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
    43921 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
    43981 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
    44041 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
    44101 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
    44161 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
    44221 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
    44281 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
    44341 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
    44401 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
    44461 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
    44521 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
    44581 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
    44641 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
    44701 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac catcatgttt
    44761 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
    44821 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
    44881 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
    44941 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
    45001 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
    45061 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
    45121 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
    45181 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
    45241 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
    45301 acgagtcaat ccgccaggtc ctaaggcgaa aagacgacgt ttgtgtgtca attcgccaag
    45361 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
    45421 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
    45481 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
    45541 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
    45601 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
    45661 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
    45721 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
    45781 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
    45841 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
    45901 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
    45961 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
    46021 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
    46081 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
    46141 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
    46201 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
    46261 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
    46321 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
    46381 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
    46441 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
    46501 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
    46561 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
    46621 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
    46681 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
    46741 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
    46801 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
    46861 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
    46921 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
    46981 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
    47041 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
    47101 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
    47161 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
    47221 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
    47281 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
    47341 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
    47401 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
    47461 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
    47521 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
    47581 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
    47641 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
    47701 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
    47761 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
    47821 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
    47881 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
    47941 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
    48001 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
    48061 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
    48121 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
    48181 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
    48241 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
    48301 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
    48361 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
    48421 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
    48481 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
    48541 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
    48601 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
    48661 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
    48721 gggagtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
    48781 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
    48841 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
    48901 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
    48961 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
    49021 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
    49081 atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa cggctttgct
    49141 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
    49201 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
    49261 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
    49321 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
    49381 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    49441 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    49501 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    49561 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    49621 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    49681 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    49741 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    49801 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    49861 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    49921 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    49981 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    50041 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    50101 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    50161 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    50221 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    50281 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    50341 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    50401 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    50461 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    50521 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    50581 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg atgacttctg
    50641 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    50701 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    50761 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    50821 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    50881 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    50941 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    51001 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    51061 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    51121 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    51181 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    51241 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    51301 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    51361 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    51421 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    51481 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    51541 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    51601 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    51661 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    51721 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    51781 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    51841 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    51901 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    51961 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    52021 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    52081 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    52141 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    52201 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    52261 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    52321 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    52381 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    52441 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    52501 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    52561 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    52621 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    52681 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    52741 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    52801 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    52861 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    52921 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    52981 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    53041 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    53101 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    53161 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    53221 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    53281 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    53341 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    53401 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    53461 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    53521 tgatagctca gattcatca
//
LOCUS       DBBGRF010000017        52130 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000017 DBBGRF010000000
VERSION     DBBGRF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.017"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            320..1165
                     /locus_tag="ACIZD4_001086"
     CDS             320..1165
                     /locus_tag="ACIZD4_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC5990036.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1446..2666
                     /locus_tag="ACIZD4_001087"
     CDS             1446..2666
                     /locus_tag="ACIZD4_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HGC5990037.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2663..5383
                     /locus_tag="ACIZD4_001088"
     CDS             2663..5383
                     /locus_tag="ACIZD4_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5990038.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5367..6311
                     /locus_tag="ACIZD4_001089"
     CDS             5367..6311
                     /locus_tag="ACIZD4_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC5990039.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6380..7390)
                     /locus_tag="ACIZD4_001090"
     CDS             complement(6380..7390)
                     /locus_tag="ACIZD4_001090"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC5990040.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7570..7914)
                     /locus_tag="ACIZD4_001091"
     CDS             complement(7570..7914)
                     /locus_tag="ACIZD4_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGC5990041.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7907..8341)
                     /locus_tag="ACIZD4_001092"
     CDS             complement(7907..8341)
                     /locus_tag="ACIZD4_001092"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGC5990042.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8479..9216
                     /locus_tag="ACIZD4_001093"
     CDS             8479..9216
                     /locus_tag="ACIZD4_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990043.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9209..10420
                     /locus_tag="ACIZD4_001094"
     CDS             9209..10420
                     /locus_tag="ACIZD4_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990044.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10624..11406
                     /locus_tag="ACIZD4_001095"
     CDS             10624..11406
                     /locus_tag="ACIZD4_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HGC5990045.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11476..12138
                     /gene="trmB"
                     /locus_tag="ACIZD4_001096"
     CDS             11476..12138
                     /gene="trmB"
                     /locus_tag="ACIZD4_001096"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGC5990046.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12236..13990)
                     /gene="ade"
                     /locus_tag="ACIZD4_001097"
     CDS             complement(12236..13990)
                     /gene="ade"
                     /locus_tag="ACIZD4_001097"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HGC5990047.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14122..15051
                     /gene="comGA"
                     /locus_tag="ACIZD4_001098"
     CDS             14122..15051
                     /gene="comGA"
                     /locus_tag="ACIZD4_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGC5990048.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15008..16057
                     /gene="comGB"
                     /locus_tag="ACIZD4_001099"
     CDS             15008..16057
                     /gene="comGB"
                     /locus_tag="ACIZD4_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGC5990049.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVSA
                     AVLLPVYGSIEEVLP"
     gene            16054..16332
                     /gene="comGC"
                     /locus_tag="ACIZD4_001100"
     CDS             16054..16332
                     /gene="comGC"
                     /locus_tag="ACIZD4_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HGC5990050.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16307..16777
                     /gene="comGD"
                     /locus_tag="ACIZD4_001101"
     CDS             16307..16777
                     /gene="comGD"
                     /locus_tag="ACIZD4_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGC5990051.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16749..17096
                     /locus_tag="ACIZD4_001102"
     CDS             16749..17096
                     /locus_tag="ACIZD4_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990052.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17059..17484
                     /gene="comGF"
                     /locus_tag="ACIZD4_001103"
     CDS             17059..17484
                     /gene="comGF"
                     /locus_tag="ACIZD4_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGC5990053.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17456..17815
                     /gene="comGG"
                     /locus_tag="ACIZD4_001104"
     CDS             17456..17815
                     /gene="comGG"
                     /locus_tag="ACIZD4_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGC5990054.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17987..18994
                     /locus_tag="ACIZD4_001105"
     CDS             17987..18994
                     /locus_tag="ACIZD4_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC5990055.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19019..20203
                     /locus_tag="ACIZD4_001106"
     CDS             19019..20203
                     /locus_tag="ACIZD4_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HGC5990056.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20640..22223)
                     /gene="abc-f"
                     /locus_tag="ACIZD4_001107"
     CDS             complement(20640..22223)
                     /gene="abc-f"
                     /locus_tag="ACIZD4_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HGC5990057.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22328..22456)
                     /locus_tag="ACIZD4_001108"
     CDS             complement(22328..22456)
                     /locus_tag="ACIZD4_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990058.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22801..22944)
                     /locus_tag="ACIZD4_001109"
     CDS             complement(22801..22944)
                     /locus_tag="ACIZD4_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HGC5990059.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23166..23645)
                     /locus_tag="ACIZD4_001110"
     CDS             complement(23166..23645)
                     /locus_tag="ACIZD4_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC5990060.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23718..24002)
                     /locus_tag="ACIZD4_001111"
     CDS             complement(23718..24002)
                     /locus_tag="ACIZD4_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990061.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24080..24274)
                     /gene="ssrS"
                     /locus_tag="ACIZD4_001112"
     ncRNA           complement(24080..24274)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACIZD4_001112"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24346..25632)
                     /locus_tag="ACIZD4_001113"
     CDS             complement(24346..25632)
                     /locus_tag="ACIZD4_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGC5990062.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25770..26441
                     /locus_tag="ACIZD4_001114"
     CDS             25770..26441
                     /locus_tag="ACIZD4_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HGC5990063.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26407..26895
                     /locus_tag="ACIZD4_001115"
     CDS             26407..26895
                     /locus_tag="ACIZD4_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGC5990064.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26908..27855
                     /gene="prmA"
                     /locus_tag="ACIZD4_001116"
     CDS             26908..27855
                     /gene="prmA"
                     /locus_tag="ACIZD4_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGC5990065.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27856..28620
                     /locus_tag="ACIZD4_001117"
     CDS             27856..28620
                     /locus_tag="ACIZD4_001117"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGC5990066.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28853..31066
                     /locus_tag="ACIZD4_001118"
     CDS             28853..31066
                     /locus_tag="ACIZD4_001118"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGC5990067.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31077..31523
                     /gene="dtd"
                     /locus_tag="ACIZD4_001119"
     CDS             31077..31523
                     /gene="dtd"
                     /locus_tag="ACIZD4_001119"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGC5990068.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31694..32953
                     /locus_tag="ACIZD4_001120"
     CDS             31694..32953
                     /locus_tag="ACIZD4_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HGC5990069.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33042..33989)
                     /locus_tag="ACIZD4_001121"
     CDS             complement(33042..33989)
                     /locus_tag="ACIZD4_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGC5990070.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34383..35675
                     /gene="hisS"
                     /locus_tag="ACIZD4_001122"
     CDS             34383..35675
                     /gene="hisS"
                     /locus_tag="ACIZD4_001122"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGC5990071.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35690..37459
                     /gene="aspS"
                     /locus_tag="ACIZD4_001123"
     CDS             35690..37459
                     /gene="aspS"
                     /locus_tag="ACIZD4_001123"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGC5990072.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37568..38443
                     /locus_tag="ACIZD4_001124"
     CDS             37568..38443
                     /locus_tag="ACIZD4_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC5990073.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38709..40592
                     /locus_tag="ACIZD4_001125"
     CDS             38709..40592
                     /locus_tag="ACIZD4_001125"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGC5990074.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40667..40951)
                     /locus_tag="ACIZD4_001126"
     CDS             complement(40667..40951)
                     /locus_tag="ACIZD4_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGC5990075.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40941..41675)
                     /locus_tag="ACIZD4_001127"
     CDS             complement(40941..41675)
                     /locus_tag="ACIZD4_001127"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGC5990076.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41804..42427
                     /locus_tag="ACIZD4_001128"
     CDS             41804..42427
                     /locus_tag="ACIZD4_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGC5990077.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42619..43740
                     /locus_tag="ACIZD4_001129"
     CDS             42619..43740
                     /locus_tag="ACIZD4_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HGC5990078.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43747..46875
                     /locus_tag="ACIZD4_001130"
     CDS             43747..46875
                     /locus_tag="ACIZD4_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5990079.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46894..50088
                     /locus_tag="ACIZD4_001131"
     CDS             46894..50088
                     /locus_tag="ACIZD4_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HGC5990080.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50234..50941)
                     /locus_tag="ACIZD4_001132"
     CDS             complement(50234..50941)
                     /locus_tag="ACIZD4_001132"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC5990081.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51706..52104
                     /gene="spxA"
                     /locus_tag="ACIZD4_001133"
     CDS             51706..52104
                     /gene="spxA"
                     /locus_tag="ACIZD4_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HGC5990082.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT        17103 a         9068 c        10787 g        15172 t
ORIGIN      
        1 gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt gaactaatag
       61 agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat agttggttat
      121 tataaaatag taatatagct gatttggatt caattcatat ttatttataa atcaaaaata
      181 cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta cttacttaaa
      241 ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc agtgaattta
      301 taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt tagacggtac
      361 tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga aacatttacc
      421 ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta ataatattct
      481 caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg gatttgatgg
      541 agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa ttgattctgt
      601 cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat ctcagaatta
      661 taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta tcaaagagct
      721 aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata atattgagga
      781 aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc ctaatcgtca
      841 attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg ttactgaatc
      901 ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg tgtttgatcg
      961 tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag atagtttaaa
     1021 tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata gtcatcaaga
     1081 aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag tatctcaagc
     1141 atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata gaattctaaa
     1201 tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt caaacgaagc
     1261 gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt tttttcgaat
     1321 aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac gaacaaattt
     1381 tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa aggaggaaat
     1441 ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca tttgaaggac
     1501 tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg accgttttat
     1561 caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt gcaggagata
     1621 attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa cagatgaaac
     1681 ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat ttctatcaaa
     1741 aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc gaaacggtag
     1801 agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga tttagttatc
     1861 gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa ctcacagatt
     1921 accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac tatgctcctt
     1981 tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg catatccatg
     2041 tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct caaggtcata
     2101 ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa ggaagttgcc
     2161 aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata tcattgagga
     2221 aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca aaagtagagg
     2281 atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat acagatgttt
     2341 tggaacggat acaatcagga gagctattag actatttgtt agaggaattc tcagatagga
     2401 taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat acgaagaccc
     2461 cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag acacctcaag
     2521 atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga atattgagcg
     2581 aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt aatcaagatt
     2641 ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg cttttggaaa
     2701 atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg ggggaaacga
     2761 agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt tcccttcaaa
     2821 aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg gcaaaatatg
     2881 gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc aaaatcgcgg
     2941 aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag aaaaactgat
     3001 cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag agcagttgat
     3061 ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt taggcatcac
     3121 gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac aacaattatt
     3181 caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga aagagctgca
     3241 agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga tccaacaaga
     3301 acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg cgaacaaaca
     3361 attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat ggcaatctct
     3421 caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc tggagtcttt
     3481 ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa cactggaaaa
     3541 gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc aggagcagga
     3601 actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag aatggcaaag
     3661 attacaaatt gagactagag aaacaaattc agaattgaag attttggaac aaaggtggca
     3721 ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga agcatcttct
     3781 ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc tccaaatagc
     3841 taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga cctatccagc
     3901 attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt atatgctgat
     3961 ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga aagtgatcct
     4021 tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac caaaaattaa
     4081 aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag gacaacttga
     4141 tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg gagaagaaaa
     4201 acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag gaaagatgga
     4261 tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga aattatatgg
     4321 cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac gacaaatcga
     4381 ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa tttcagaaaa
     4441 aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg ccagaagcta
     4501 tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac aaaaagtatg
     4561 gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt cggaagtacc
     4621 tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca atgaattatc
     4681 ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat ctgtaagact
     4741 gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag caagtgaaaa
     4801 tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat tggacgaact
     4861 ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg aatggggagc
     4921 acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg aaagacaatt
     4981 accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag gaaattatca
     5041 gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag aatttcccat
     5101 ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat ttgcttacct
     5161 ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct ggcttcatta
     5221 tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag aaaagtatca
     5281 aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga tgaaccaaat
     5341 cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta atcgatgagc
     5401 agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa aacggaaaaa
     5461 aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa tactgggatg
     5521 cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta aacggtaaaa
     5581 gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta acaagggtag
     5641 atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa gaagaaatgg
     5701 aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat cgtattgttc
     5761 gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca aaaagaaacc
     5821 atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac ttagggaaat
     5881 caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt atcattttgc
     5941 atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat acgcttgcag
     6001 gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc tgtcttgcgt
     6061 tgaaaatcag cgaagctgac gaagatgttc ttgtattacg tcatatggtt ttagcacacc
     6121 atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca gaaatattac
     6181 atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt cgtcaaacag
     6241 aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc tatgtaccaa
     6301 aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag acataagtct
     6361 tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt gaagattctt
     6421 ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt tcacttgagt
     6481 ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag gcatcatctt
     6541 tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg aatgcattgt
     6601 cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta tccatgtcat
     6661 tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca taagaagtag
     6721 gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa gctgcttctt
     6781 ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg ccatcttctt
     6841 ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct ccatcatccg
     6901 ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt tgtgcttcta
     6961 cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata tctacgtgag
     7021 ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa gtatctttcg
     7081 tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc gcttgtttgt
     7141 cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta ttgaatactt
     7201 tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt gcttcatcat
     7261 agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta ttagtatcgc
     7321 ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa ataattgatt
     7381 tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata ttaactatac
     7441 catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt caaaatttca
     7501 tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct gttgagaaaa
     7561 taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt tttctacttg
     7621 ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga tatctttttt
     7681 gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt cgatcaatgc
     7741 gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg cttcttccaa
     7801 ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata acagacctcc
     7861 gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa tcatcgcagg
     7921 acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca taactatctt
     7981 gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg actaaatgga
     8041 tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag atattaagac
     8101 ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca cgcgaaaaaa
     8161 cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt ttaggcacaa
     8221 ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc ttgtcgtctt
     8281 catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata cagttttcca
     8341 tataaaacat cctttctata aagaataaat acttcagctt aactttacca taagttaaag
     8401 ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata aataaaaata
     8461 aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg gtacggacat
     8521 ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt agggttgatt
     8581 ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct gctggaagct
     8641 tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga agaatatcgc
     8701 aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac attgagagaa
     8761 catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat gaaaagagca
     8821 gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc agctaatttt
     8881 tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga gccttcttta
     8941 tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc attgcttgaa
     9001 ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca tattttagct
     9061 actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat acgagcagac
     9121 ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt ggacgaaatc
     9181 tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac gtttagcaag
     9241 acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt ttgttttagt
     9301 ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga aaaccctgca
     9361 gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct gtttattcgt
     9421 gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc ctaaagaaaa
     9481 agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc cgttgatctt
     9541 tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg agcaatcctt
     9601 ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc atctgcaaat
     9661 caagagagca gaattgtttc gactagatca acaagttatt cgttattgga aattaggctg
     9721 gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat gggcaggaat
     9781 agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc aacaagaaaa
     9841 aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc agatctatca
     9901 atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa gaagacgcta
     9961 tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc tttacttgtt
    10021 tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat tagtaattat
    10081 aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta tcggtttctt
    10141 atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc gctatatggt
    10201 tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc agtatctact
    10261 cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag tcgtattaga
    10321 tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc tctttgttaa
    10381 actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct gtgtagggta
    10441 aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct attttttttg
    10501 agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt gcttgacgtg
    10561 tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag gacgggagaa
    10621 tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa aggcgacaca
    10681 ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg aaacacgact
    10741 ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg gacaaaacga
    10801 acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt gctgactcct
    10861 aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca tcattcaaat
    10921 tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga gaagatgctg
    10981 caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct gcaaattgtc
    11041 catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc agtagtacac
    11101 ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct agtcgattgg
    11161 gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg aaattatgtg
    11221 ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac tgacgaaatg
    11281 cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac cagatattgc
    11341 aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg aattttcagt
    11401 ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat tagaggaaag
    11461 gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat gttagcggct
    11521 cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa tgaattgttt
    11581 gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt catcactgga
    11641 atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt cagtgttgtt
    11701 tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact tctacatgtg
    11761 gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat ctatctgaat
    11821 ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata taagactttt
    11881 cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa aacagataat
    11941 caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat cctcaaacag
    12001 gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga gtatgaagaa
    12061 aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca agataagacc
    12121 aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat atccataaat
    12181 aaatctcaga aaatgaacat tacagatgta atgtattttc tgggatttat ttgatttaaa
    12241 atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga gaaaatgaaa
    12301 ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag aaagaaagtg
    12361 tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt attaattcat
    12421 tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct ataggaagag
    12481 aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct ttttgaatca
    12541 aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact agattatgcg
    12601 agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct ttcactatgc
    12661 ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt aattggtctt
    12721 tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc aaatctttag
    12781 tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa agaagcagct
    12841 ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac gtatatgaat
    12901 ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact aatgttccct
    12961 tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag aaatcagctt
    13021 gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct gcattcaatg
    13081 ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga cggacgatat
    13141 gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg acaaagaagc
    13201 atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct tttgcaacgg
    13261 tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct tcttttgcag
    13321 ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac tcttccatgc
    13381 cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat tggatctttt
    13441 ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca gctaagccta
    13501 aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt gcaccattgg
    13561 tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc atgagtgttt
    13621 gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt cctatttcat
    13681 ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa aattcgcttg
    13741 gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc actagatatt
    13801 gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg atcattcctt
    13861 cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg atcttagcat
    13921 gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat ttccttaatg
    13981 ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata aattcggctt
    14041 ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa aagacgtatg
    14101 ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat gataagtgaa
    14161 agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt attttacatc
    14221 tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc agatggacag
    14281 caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa aagaaaagct
    14341 cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg gttgtcttct
    14401 gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg tacttttgaa
    14461 acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa aaccgtcaga
    14521 cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct aatgtatcgg
    14581 ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga gatagaagaa
    14641 ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga tacacttttg
    14701 aaactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag agatgaatca
    14761 actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc aaccgtacat
    14821 gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa aaaagaagag
    14881 ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc caatcaccat
    14941 ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa atcatgggag
    15001 gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta aaggattaac
    15061 aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat ctggttttag
    15121 tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg ttattttggc
    15181 aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt cgcaaatagg
    15241 atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga atctgccgac
    15301 aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca atgatttgaa
    15361 aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct tgtttagtat
    15421 gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag agcattgggg
    15481 tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag cggttactct
    15541 attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc agagtgaatg
    15601 gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg cttatttgtc
    15661 actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca tagtctgctt
    15721 aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga ttcaaggatt
    15781 ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat cagaagaatt
    15841 cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac tgatttttta
    15901 cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc attttattca
    15961 gccaatcatt tttttgggcg tagcggcttt gattttatta gtttctgccg ctgttttatt
    16021 acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat atcttattat
    16081 agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt attagtgttg
    16141 ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag tcgtgaagcg
    16201 atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa tggaagagtt
    16261 cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc agaaatctat
    16321 cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat cactcttact
    16381 gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg catggaagaa
    16441 tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt ctacgcaaaa
    16501 aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag agaatcaaat
    16561 catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata ttcctgatga
    16621 gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga atgaaagttc
    16681 actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt atcaattcca
    16741 gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt ttgttggagt
    16801 cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt ggccagctgt
    16861 ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga atgatttatg
    16921 aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa gaaatgatcc
    16981 catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt gtcaatatgg
    17041 agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct gattgaatgt
    17101 ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt gattcagcaa
    17161 accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct aatattttta
    17221 gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa tcagcaactg
    17281 cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat gatacgtaaa
    17341 agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct tcaattattg
    17401 gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga tggatatgcc
    17461 atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat tttctgtctt
    17521 gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct accgtttgtc
    17581 aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga agcagatggc
    17641 tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact acacaactgg
    17701 atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag tctcaccgtt
    17761 tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag aatgatggaa
    17821 tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa aatgtttgcc
    17881 gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc gatagaatta
    17941 aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt taccagaaaa
    18001 aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga atgcattggg
    18061 aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg attatcaagt
    18121 acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag ctctttatga
    18181 agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc aattactttt
    18241 attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc ctgatagtat
    18301 cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag caccggttaa
    18361 gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt taaacctatc
    18421 gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat tgttggctgt
    18481 cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc aagacgggtt
    18541 gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa tcggttatta
    18601 tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc atagttatgc
    18661 acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt ttggtttgtt
    18721 tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa aatggtttaa
    18781 agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc gtaataaaca
    18841 atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac aagtaaaaga
    18901 agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg aatttttcaa
    18961 cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg agagtcatat
    19021 gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat tatatcaaat
    19081 gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac aagattctat
    19141 ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata tcgaaaacca
    19201 cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt taagctctta
    19261 tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt atggggattc
    19321 agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat ttgctccttt
    19381 gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac ctgacatttt
    19441 gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa attatttata
    19501 tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct tccatggcac
    19561 aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga tcgaagaact
    19621 aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg atggaggtaa
    19681 atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg gtacacgttc
    19741 aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga ttgatattga
    19801 tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag gattgtctag
    19861 tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag cttatgacat
    19921 tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga atggtgttga
    19981 tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta gtgaaatcat
    20041 caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat tgcgtggtga
    20101 agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc caacagatga
    20161 ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag cattcgttag
    20221 gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt gcggagaaga
    20281 ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt cttagggaat
    20341 tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg attttcagga
    20401 aaatcccaat attttatttt cattcatctt tataagggac attacatatg taaaaagaaa
    20461 aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta tgtttagcta
    20521 gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc cacctgtact
    20581 ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga aaaaacgtcc
    20641 tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat aacgagtgct
    20701 tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag cgttccttga
    20761 tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg attggttggt
    20821 tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc caaacggatt
    20881 ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata aaagccactt
    20941 ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc gtaagccagc
    21001 aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat ttgcaagcta
    21061 ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa tttgagtaag
    21121 gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg atagactgca
    21181 aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt ttgaatgatg
    21241 aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt tttcggggga
    21301 ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt ggcttttttg
    21361 aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat catgactttc
    21421 aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc caagcgagct
    21481 tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc accttcttcc
    21541 agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga aacgaccaga
    21601 accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt aagatctaaa
    21661 tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat tttggctaaa
    21721 gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg acggtgtgga
    21781 atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc gcctagttct
    21841 tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt tgtatctggt
    21901 tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat ctcagcggca
    21961 gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg ttcgaccgtc
    22021 ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc tctgccggtc
    22081 aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc aattttttca
    22141 ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat tgttttttta
    22201 atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa aggccatggt
    22261 tatccctggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct tgagatggcc
    22321 attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca gcaactgtaa
    22381 aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta cttgttattt
    22441 tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc agtgtacctg
    22501 aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga tgtgtaattc
    22561 tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca tcattgtatt
    22621 ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac tttgtctaca
    22681 tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct ctttggaaat
    22741 ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg tagcctttca
    22801 tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc cgaacccgaa
    22861 ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat attttttcgt
    22921 atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat gcttaggtcg
    22981 ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttat tttacttgaa
    23041 ctcattgact gttttccctt tattttaaac attataaaga ccgatgagtg cttgccgcgt
    23101 cttttgtttt tatcacggtt ttttgtgcaa aaaaacctgc cgatagttgg caggtcgtct
    23161 acgtgttaag ctttggtgtg gtctttagct ggcaattggt tttctaaatc agttcggaca
    23221 acaagcacat cgcaagctgc gtttctaata acatattcag aaacagaacc aataaataaa
    23281 cgttctacag cattcaatcc tgtggctcct aacataatca aatctacttg attatcttct
    23341 gggatttctc tggcaataat ttgttttggt gagccatatt ctacgacaga ggttacatta
    23401 ttcaagccag ctttcttcgc attgctttca taatctgcca atgtttgctt tgccatttca
    23461 gtagcttgtt ctgcaagcat tccatcaaag gatgaaacgg tttggaaaga acgtgtgtca
    23521 atgacatgtg ctaatagaag ttctccgtta tttcggatag ctacattgac cgccttttta
    23581 aaagctaatt cagcttcatc agaaccatct acggcaacca tgattttttt gtattgttgt
    23641 aacataagca ttcactcctc aagtcaatcg tattgtactc ttttattgta gaacacttta
    23701 gggaaaaaga gaattattta ctgctttggt tcagcaattt tttttgcaaa tcggatactg
    23761 aaggtggcag aaacaataat tacgatcagt aaaaagacca aggcaataaa gcgttgattg
    23821 aaaaaagctg ttaaaatacc cattacgcct aaaacagcat atgcagcacc gtaaaattgt
    23881 aggaatcctt gatttttatc atttttgttg atcaatacaa aaaagatatc ctgtttatta
    23941 aataaataat agctaacgaa taataatact aaagtggcga taatcattaa aatcctaatc
    24001 atgaacaaat cctccaaaat aagcaacaaa tagaaaaagc aatttgccaa gagcaaattg
    24061 ctttattctt taaaagatgg taatctccgt taatgccgtt gtttgtcctg tagtattgat
    24121 cccgcgaatt caagcaggtg ggtcccatgg tcgtagcttc gaactaccaa atgataaggc
    24181 atgttaccag cagtgacaca agacgggtcc caagatatca ataaaaatgt tcggtcaaca
    24241 cacaaagagg acaattcgaa catcacagat ttcccacctc tatagtagca tatgaattta
    24301 aaaagagcaa tgagagagct cgcagaaaca gaaccgtttt cttgtctagt tttttggagg
    24361 atgctttttc cactctttta tacggtaata ctgttgaccc agagcctgtt catatttccc
    24421 tgtatctttt ggctgataat actgagcatt cttcagttta tctggtaaat attgctgatt
    24481 gacccaagcc tgatcaaaat gatgaggata ctgataaccc acgccacggt tgagtgattt
    24541 cgcacctttg taatggctat ctctcaaatg atcaggaaca tctccagctt tgccctctcg
    24601 aatatcagca agtgctgcat ctaatgccat gtaggcagaa ttggattttg gcgacaagca
    24661 aagatcgacg acgacgtctg ctagtgggat acgtgcctca ggcaatccca atttttcagc
    24721 agctaataca gcgttcactg tacgagccgc agcagcagga ttacctaaac ctatatcttc
    24781 ataaccgata accatcagac gccggcaaat acttgccaga tcacctgcct caactaaacg
    24841 ggcgagataa tgaagtgcag catccacatc acttccacga atcgattttt gaaaagccga
    24901 aataacgtca taatgagcat ctccattttt gtcatgggta agagcttttc tttggacaca
    24961 ttcttcaatg atcgacagtg taagatgaat ccttccttct ttatctgaag gagtcgatag
    25021 tgtagccagt tccagcccat tcaatgcact ccgcaaatcg ccgttcgttg cacgcgaaag
    25081 gtgaagaaga gcatcttcgt ctaactggat tgcttgttgt ccaaggccgc gttctttatc
    25141 ccttaaagca tgttcgactg ccaactggat gtcttgttct gttaatggtt tgacttcaaa
    25201 gatctgtgta cggctgcgga tcgctggatt gatggtaata taaggattct cagtagtcgc
    25261 tccgatcaag atgattcggc cactttctaa atgaggaagc agaaaatcct gttttgtttt
    25321 atctaatcgg tgtacttcat ccaataagag gatcactgta ccactcattt ttgcttcttc
    25381 cgctacaact tgtagatcct tttttgaatc tgtagcggcg tttagcatgc gaaatgcata
    25441 attagtagag ccggcgatcg cacttgcgat actcgttttt ccagtaccag gaggtccata
    25501 tagaatcatg gaagagagca tgcgagcatc gaccatgcgg cgtatgattt ttccttcccc
    25561 gactagatgc tgctgaccaa cgacttcatc gatcgttcga ggtctcatgc gataagccaa
    25621 tggctgttgc ataggatttt cctccttctt gtttttacgt cccttaatta tatcatattt
    25681 agcaagatgc ctagaaagaa cagccttctg ttgttttgtt ttcatagctt atccaactaa
    25741 tattgtgtat gataaagtag gtgagaaaaa tgacggataa acaaaagata gatgaatttt
    25801 tttggaataa aacgacgcca gaagtggcac gggatttatt ggggatgtat ttggagcatg
    25861 acacaccaga aggaagatta gctggatata ttgtagacgc ggaagcatac ctaggtccag
    25921 aagacgaggc cgcccatagc tatggtttaa gaagaacacc gcgtgtgcgg gcaatgtatg
    25981 aaaaaccagg tacgatctac ctttacacga tgcatactca tcggattttg aacatcatta
    26041 ctcagccaga agggattcct caaggagtaa tgatacgtgc aatcgaaccc gccgcaatga
    26101 ttgatcaaat gagtaaaaat cgtggcggaa aaactggtcc agatatcagc aacggtccgg
    26161 gaaaattagt ggaagcatta gcaattcctc aagaacttta tggtcagtct atagcagata
    26221 gttcgttacg cttagttttt gagaaaaaaa agacaccaaa aaagatcaat gctttgccta
    26281 gaatcggtat cccaaacaaa ggtgtatgga cagaaaagcc gttgcgtttt gttgtgtcgg
    26341 gaaatcctta tatctcttta caaagaaaaa accaaatcga gaaagattgg ggttggagga
    26401 aagaaaatga aaaagaagga tctattaaca tatttagatg aaataattga aaaacaagtg
    26461 acagactatg atgtagcttt agattgggat acaaaaaatc atacgatcga gatcgttgtt
    26521 cgcttgtttg cagaaaataa agcacaattt gagattgatg atgcagaagg gatcgtttcg
    26581 caagaaccaa ttatcgaatt tgaagacggc gtacttcttt ttaatcctca gaaatctgtt
    26641 tttgatgaac gcaattatct agcagtaatc ccttatgaag gaaaaaaagg gttggcaaaa
    26701 tcagtagctg attctttagt ggaatatcta aatgaagtat tagctcaagg gcaaagcgat
    26761 ttgcttgatt ttttggatga agacgatgac gaagctgtat tcgagcttca ctgggataat
    26821 caacaactag cagaattagt agaagtaaaa cagcaaaatg aagcagatac ttatttaccg
    26881 tacccaagtt attaaggagt gacagatatg aaatggaatg aagtaaaagt agaaactgaa
    26941 agtgaagcag tcgaagcagt tgctaatatt ttgatggagg caggggcgag tggtgtcgcg
    27001 attgaagatt ctttagatgt tgaacatttt cagtcggatc aatatggtga gattttagat
    27061 aaaaatgatt ttacatcgct gaaagaaggc gcactagtca tggcttattt tccggaaacg
    27121 actttcttac cggaaatctt gccttttatc aaagatcgta tcacacaatt acctgagttt
    27181 ggtctagcta ttggaaaaaa taaagtaaca gttagtgaag tagaggaaag caactgggca
    27241 acagcctgga agaaatacta tcatccggtg cgtattacgc gaatgctgac ggttgcgcca
    27301 agctgggaaa actaccagac agaagatcct ctagaaaaaa ttatcacact agatcctggt
    27361 atggcatttg gcacaggcac tcatcccacg acttccttga cattgacagc actagaaaca
    27421 gtcttgcgtg gtggtgaaac attgctagat gtgggaactg ggtcgggcgt gctaagtatt
    27481 gcagcaaaat atcttggtgc aaaagatgtc tatgcctttg atttagacga agtagccgtt
    27541 cgttcggcga aagaaaatat ggatatgaat gaaatagcca aagatgtcca tgtatcagct
    27601 aacgatcttt tgacaggaat cgagattgaa agtgatgtaa tcgttgcgaa cattttagca
    27661 gatatcatct tattgatgat cccagatgct tggcgtttac tgaagcaaac aggcacgctg
    27721 atcgtttcag gaatcattga agagaagaag caaatggttc tggatgccat gttagaacaa
    27781 gggtttatcg tggatcaaat tttccagcaa aaagactggt atgcaattat tttgaaaaaa
    27841 ccagaggtgg aatagatgca gcggtatttt ttaaaagaat catatgaatc aaaagactat
    27901 tttgttttag aaggggaaaa ctatcaccac attgtacggg ttatgaggat ggaacccgag
    27961 gatgaagttt ttttggcatt caatgatcaa atagccattg ttgcagaaat cacggagatt
    28021 actgaagagg ctgtttatct gaaagaaatt aaaaaagaag aaaatcaaaa ggaactgcca
    28081 agttcgatta ccatagcgag tggctatcct aaaggggaaa agctggattg gatcgttcag
    28141 aaatccactg aattaggagc gcaagctttt cttggtttcc cggcatcagc ctctgtcgtt
    28201 aaatgggatg caaaaaaacg tatgaaacga caacaacggc ttgaaaagat tgctcaagag
    28261 gcagcggaac aatcccatcg gcagatcgtg ccatcagtag agttattgga aacgaaacaa
    28321 gatttatttg agcggctaga tgattatgac gtggtcttgg ttgcttatga ggaatcagca
    28381 aagcaaggcg aaaaatcaaa tgcagccaaa attcttagtg aaacaaaacc agatagtcga
    28441 atcttagctg tctttggacc agaaggtgga ttatcccgcg atgaagtcga ttattttgta
    28501 gaacacaaag ggatactttg tggattagga ccaagaatcc ttcgtacaga aacagcacct
    28561 ctttatttat taagtgctgc tagctatcaa tgggaattaa tgaatccttc tttcagctaa
    28621 cgttcttcat taataaaaga gtatcgacag aaagaattga aaaaatagtc aacaatttgt
    28681 ataatagaaa caattattta tacaatggat acgaaaaatc gtttgaaaaa gcttttaaaa
    28741 agcgaacatt tccgtaaaaa aacgtataac tgcacggatt ttgggacaat tatcaaacag
    28801 atatttgtcc cgattcccgt tttaccgaaa aaagaaaggg ggatcgattc ctgtgacaaa
    28861 agaagaaatt ttaacgggac ccggtgtcat aaagctcgtt agtcaataca tgggtcccga
    28921 acatgtagca tttgttgaga aagcatgcga atacgcgact gctgcacatg acggacagtt
    28981 tagaaaatca ggcgaaccct acattattca tcctatccaa gtcgcaggta tattagcaga
    29041 tttaaaaatg gatccccata cagtggctac aggcttctta catgatgttg ttgaagatac
    29101 agaaatcact ttagaagatc tgagagaaga atttggcgat gacgttgcta tgttagtgga
    29161 cggcgtaacc aaattaggga aaataaaata taaatcccac gaagagcagc tagcagaaaa
    29221 ccaccgaaag atgctgctag caatggctca agatttacga gttatcatgg tcaaattagc
    29281 tgatagacta cataacatgc gtacgttgaa gcacctgcga gaagataagc aaagaaggat
    29341 cgctcaggaa actttagaaa tctatgcgcc tcttgcacat cgtctaggga tcagccggat
    29401 caaatgggaa ttagaagata cagcacttcg ttatctaaat ccaaaacagt attaccgtat
    29461 cgtccacttg atgcagacga agagagaaga acgtgaaaaa tacgtaagtg gtactgttga
    29521 agatattcga atagcgacag aagagctggg gatttttgca gaaatctatg gacggccaaa
    29581 acacatttat tcaatctatc gtaaaatgaa agatcagaaa aagcagttca acgaaattta
    29641 tgacttgcta gctattcgag tgatcgtaga ttcaatcaag gattgttatg ctgtattagg
    29701 agcaatccac acaaaatgga aaccaatgcc cggcagattt aaggattata ttgccatgcc
    29761 aaaagctaat atgtaccaat ctttgcatac taccgtgatc ggtccggcag gaaatccggt
    29821 agaaattcaa atccgaacac aggaaatgca tgaaatcgct gaattcgggg ttgctgcaca
    29881 ctgggcctat aaagaaggaa aaaatgaaaa agtagaacca gatggtatga cgaaacaatt
    29941 aagctggttc catgagatac tcgaacttca agacgaaagc tatgatgctt ctgaatttat
    30001 ggaaggcgta aaaggagata tctttagtga taaagtctac gtcttcacac caaaaggaga
    30061 cgttactgag ttaccaaaag gatccggacc attggacttt gcatacagta tccatacaga
    30121 tatcggtaac aaaaccactg gtgcaaaagt aaatggcaaa atggtgcagc ttgattacaa
    30181 attgaaaaac ggagatatca ttgagatcat gacttctcca aattcatttg gcccaagtcg
    30241 cgactggttg aaattagttg ctactagcaa agcaagaaat aagatcaaac gtttcttcaa
    30301 agcccaagat cgagaagaaa atgtgatcaa aggccacgaa tccgtggtca aatgtattac
    30361 agatctagga tttacgccta aagatatttt gacgaagaac aaactgcaag aagcactcga
    30421 tcgttttaat tatcaaacag aagatgatct ctatgcagct gtagggtatg gagaagttag
    30481 ccccttgacg atggccaatc gtctgactga aaaagaacgt aaagaacaaa aaatcgagca
    30541 gcaaaagcaa gaagcagaag aaatcatgaa tcagccgaaa aaagaacctg acaaaatgaa
    30601 agtacgtcat gaaggtggcg ttgtcattca aggggtagaa aacttactaa ttcgtatcag
    30661 tcgctgctgt aatccgattc ctggtgatga tatcgttggt tatatcacta aaggcagagg
    30721 gatatccatt catcgtcgag attgtccgaa tgttcagcct gacaaaccaa atgtagcaga
    30781 acgtttgatt gaagtcgaat gggaagatac atcgaataca cgaaaagagt atgatgcaga
    30841 tttggaaatt tacggctata atcgttcagg cttattgaat gatgtacttc aaacagtcaa
    30901 tgcgctaacg aaaaatctca acagcgttga agcacggacg aataaagata aaatggcgac
    30961 gatccatttg acggttggta tccagaattt atcccaccta aagagtatcg tggataaaat
    31021 caaagcagta cctgatgtct acagtgtacg ccggacgaat ggataggagg acagatatga
    31081 gagcagttgt tcaacgggta agtaaagctg ctgtgtcagt cgatcagcaa gaaattggaa
    31141 aaattggcta cggcctactt gttttattag gcattcatga aaccgatacg caaaaagatg
    31201 tggactatct ggtaaaaaaa attgcacaaa tgcgtatttt tgaagatgaa caaggaaaaa
    31261 tgaatattag tgtagaagat gtgggaggac aaattttaag tatctctcaa ttcacactgt
    31321 ttgcggatac gaaaaaagga aatcgaccaa gctttgtgga agccgcacga ccagaaacag
    31381 ctattccttt atacgaatca ttcaatgaag gaatcagaag tcgcggcatc acagtcgcta
    31441 ccggacaatt cggagcagat atgtcggttt ctctcgtcaa tgatggacct gtaacgatca
    31501 ttattgattc taaaaacaaa taaagtaatc tggttttcac tagtaaaaac tatgaaacac
    31561 gtcgcttaag ttagactgat aaactctaac ttaagtggct tttttgtctg caaaaagcgc
    31621 ttcttttgtc agcagtcgga aaaaaagtta agcttaaatt atacaagtta ttttttatag
    31681 gaggttgctg aagatgaaag aagtaccagt agtagatatc aaaatcacag atttaaaaaa
    31741 attgtatcaa aaaggataca acatgttgga ggagttacgc catgaagcgg acgctcccgt
    31801 cgtcaaagca aagattttca ataaagaagc tatcacgatc tacggatcat cagcagcaaa
    31861 agtattttat gatccaagga atttcaaacg aaaaggtgct atgccaaaat tagtattgaa
    31921 gacacttttt ggtcaaggtg gagtacagac tttggatgga gctgctcatc accatcggaa
    31981 aaatattttt atggatctaa tgacaccgga aagaatggaa gattatcatc gtatcttaga
    32041 taagaatctg acacaagcac ttgaagcaca gcatggtcaa tttgaactat ttgatttaag
    32101 taagatggtt ttctttacat ctatttgcga gtgggcaggt atcaatttat cagcgatttc
    32161 taaagatgag gtcgaaaaat tagcagaata tcaaatctct atgatcagcg gaacgtttac
    32221 ttctccgatt gatcacataa aaggtgtcga gaatcgcaaa aaatcagaaa aatgggcgca
    32281 aggcttgatt gaagaagctc gacaaaatcc tgtggctgga aaagaaaatg tggcattata
    32341 tgcttttgcc aatgccacag atttagatgg tcagctttta cctctggaag tggcagctgt
    32401 tgaattattg aacatcatcc gtccaacggt tgctctaact gtgtgggcgg cattgatggg
    32461 acatgcactt ttcagtagac cagatttgta tcagcaatta aaaaatgact tttcgacgtt
    32521 acaagatccg tttattcaag aaatgagacg ctattatcct ttcttcccaa tgctacctgc
    32581 gatttcgctg aaagaagtag aagtagatgg ttatcgtata ccagaaggca gttgggttat
    32641 tttagattta tatggaacag accatgatga acgaacagtt gaagcgccag attcctttat
    32701 gatcaaacgg tatgtaggga aagcaaaaga tatttcctat aaagaagaat atgagatgat
    32761 tgcacaaggc gggggaaatt ttcgacaaat gcatcgctgt gcaggagaat ggatcactct
    32821 tcatagtcta cgtgtgtttt ccgatcagct agtaaataag tttgagttct ctgtacctga
    32881 acaagattgg acgattccat tcaatcagtt tccgacttat ccgaatagcc gagcgctact
    32941 ttacaagaat tagattagca taaacttatc gaaaaaaagg aagatcaaac agtgctgatc
    33001 ttcctttttt catattacta taaattgata aggtcaattg atcaaaatcc acgaaatgct
    33061 tcatcaatgg tttgataatc ttcattggat aaatgcaaat ctaaagcttg gacattgtca
    33121 gatacttgct ctggacgctt agctccaggt ataactacag acactcgtgg attcttcatg
    33181 taccaagcta aaacaagttg cgcaggagtg gcttggtatc ttttagcaat ggggcgaagt
    33241 acatcgacag cggttaaaat ttctctgaaa cgttctcctt ggaaatctgg atttcttttt
    33301 cgaggatctc cttcaccaaa ttgtttttcc tcaccaagtt catattttcc tgtcagcaaa
    33361 ccggaagcaa gaggaaaata gggaacaaaa ctgattttgt ttttttcaag ataagggaat
    33421 aattcttttt cagcctgccg atggatcaaa ctgtatttat cttctactac atcgacatat
    33481 ccatctgcat tcgcttcttt caattgttct aacgtgaagt ttgacacacc gactgctcgg
    33541 atttttcctg cttcttttaa ttcgtgcaat gtagcaactg attcattttt tggtgtgctt
    33601 tcatccggaa agtggatata aaaaatgtcg atgtaatcag tttgcagacg ttttagtgca
    33661 tcttccaccg attgtttgag aaactcagga gaattatcaa atgttcgccc tttatttggt
    33721 acatgagcag cttttgtagc gatgacgaca cgtgagcgat catattcttt ttccttcagt
    33781 acctcgccaa tcagttcttc ggaacggccg tttccgtaag cataagcggt atcgatcaaa
    33841 ttgatcccgc tattcaaagc tgtacgaact acttgttttc ctgtctcatc ttccaaaccg
    33901 tcaaaaagat tatgtcctcc aacggcattt gctcctaatc caagctgttc tgcgtagact
    33961 tgtgaatgtc cgattcttat ttctgccata gctgattcct cctttttgtc tagtctaaaa
    34021 caaaatacca aaaagctgaa ctaaaacgtt tttgtgaggg gaaatagtca gatatctctt
    34081 gactttgaga ctggttttta gtaggttata agtaatatcg aatgtcaatg aaagagcgag
    34141 taagtttttg aaactttaca agagaggatc atcgaggctg aaaatgatct aaagtttcat
    34201 tagcctaaag acactctgga gatggacgag tgaaaagccg tcccgcgtac gagcgttatt
    34261 cgtaagagga aagagaaatc tttcaaaatt aggtggtacc gtgtatgaat ttcattcacc
    34321 cttgttcatg atgaacaagg gtgatttttt tatttacata gctaagaaag ggagagaaaa
    34381 ctatgagttt ccaaagacca aaaggaacaa atgatatttt gccaggcgaa tcagaaaaat
    34441 ggcagtttgt cgaagaaaca gcacgtttat tattcagaga ttatcagtat aatgaaatgc
    34501 gtacaccgat ttttgaacac tatgaagtga tatcccgaag tgtaggggat acaacggata
    34561 tcgtttcaaa agagatgtat gatttttatg acaaagggga acgccatgtg acgcttcgac
    34621 cagaaggtac agcaccaatc gttcgttctt ttgttgagca taaattgttc ggcccagagt
    34681 atgcgaaacc gttcaaaact ttttatatgg gaccaatgtt tcgctacgaa cgccctcaaa
    34741 aaggacggtt acgtcaattc catcaaatcg gagtagaagc atttggatca gaaaaccctg
    34801 caactgatgt ggagagcatg gtgatggcac ttgatttctt caaacagttg gggatcacgc
    34861 aaatccggct agtcatcaat tcattaggtg ataaagaaac gcgtcaagcc tatcgtcaag
    34921 cattgatcga ctatctttta ccttttgaat cagagctgag tgaagactct aaacgccgcc
    34981 ttcatgaaaa tccattacgc gtattggaca gtaaagacaa acgagatcaa aaatttgtgg
    35041 cagaagctcc atctatctta gattatctaa gcgagcctgc tcaaaaacat tttgataccg
    35101 ttgtttccat gctggatgca ttggctgttc cttatgaaat cgacagtaat atggttcgcg
    35161 gactagatta ttacacacat acgatttttg aaatcatgag tgacgcacca aaaatggggg
    35221 cacaagcaac gatttgcgca ggcggacgtt atgacaatct agtggaagaa ctaggtggtc
    35281 cttcaacacc tggcttcgga tttgcaatgg gtatcgagcg attactcttg actatggagg
    35341 cagaggaagt agttatccct gcatttaatg agttggatgc ttacgtggtc gcactcggag
    35401 acgaaacaaa tatcgaagca ttgaaagtgg tccaagcgat tcgaaacttt ggtttttcag
    35461 ctgaccgcga cttcatgaac cgtaaagcaa aagcgcaatt taagacagca gataaagcga
    35521 atgccaaatt agtattggtg atcggtgaag atgagcttgc tagtcaaacg attaatgtca
    35581 aagcaatggc aagccgaaaa gaaaaaagtt ttccattaga agagatatat gaacattttg
    35641 atgaagtcta tgatgaaatg actttattcg agtaggagga aaaaaataaa tggcacaaag
    35701 aacgatctat tgcggattag tttccgaaca acaattagaa caaacagtta cattaaaagg
    35761 atgggtacaa aaaagacgag accttggggg agtaatcttt atcgacctac gtgatcgtga
    35821 aggaatcgtt caaatcgtct ttaatcctga aatcaacaaa gaagcatggg aaatcgcgga
    35881 taaatgtcgc agtgaatacg tgatcgaagt gactggggaa gttagaagac gcggagaaaa
    35941 tgcagtaaat cctaaaatgg ccactggtga attcgaagtg attgcaagtg aaatcgtgat
    36001 tttgaatcaa gcaaaaaccc cgccatttca aattgaagat gatcaagcaa tcagtgacga
    36061 aatacgtttg aaatatcgtt atttggatct gcgtcgtcca aaaatgacta aaaacatcaa
    36121 attaagaaat gcgacaacaa aagcgattcg tcattattta gatgataatg actttctcga
    36181 tatcgaaaca ccttacctag ggaaatctac accagaaggc gcaagagact acctagttcc
    36241 ttcacgtgtc catgctggac atttctatgc gttgccgcaa tctcctcaat tgtttaaaca
    36301 attgctgatg aatgctggat tcgaccgtta ttatcaaatc gttcgttgtt tccgcgatga
    36361 agatttacgt ggagaccgtc agcctgaatt tacgcaagta gatattgaaa caacgttctt
    36421 aacagcagaa gaaatccaaa cttacacaga gggattgatt gcgaaggtaa tgaaagaagt
    36481 tcgcggtatc gaagtcacat tgccatttcc tcgtatgacc tatgatgaag caatggctcg
    36541 ctacggcagc gacaaaccgg atacacgttt tgatatggaa ttgatcgatc taagcgatac
    36601 agtcaaagaa gtagaattca aagtcttcca aatggctctt gaaaacggcg gtgtcgtgaa
    36661 agcattgaat gctaaaggcg ctgcagatcg ctactcacga aaagacatgg atcagttagg
    36721 tcaatatgta ggacaattcg gagctaaggg gcttgcatgg ctgaaagtag aagaagacgg
    36781 attgaaaggt ccaattgcta aattcatggg agaagcaaca gaagcaatca ttaaagcaac
    36841 agatgcaaaa ccaggtgact tgctgatgtt tggcgcagat aaaagtgaaa tcgtcgctgc
    36901 tgcattaggt gctatccgga cacgtttagg aaaagaatta ggactaattg atgaatcgaa
    36961 attcaatttc ttatgggtaa ctgattggcc acaatttgaa ttttcagaag aagaaggtcg
    37021 atatgtctct gctcaccatc cattcacgat gccaaaagaa gaagatatcc cgttattggc
    37081 tgaagaccct gcaaaagtct atgcagaagc ttatgatatc gtcttgaacg gttatgaatt
    37141 aggcggaggt tctatccgta ttcatactcg tgagcttcaa gaaaaagtac tagaaactct
    37201 aggctttaca aaagaacaaa tggaagaaca atttggtttc ttgttaacag ctttagatta
    37261 cggattccct ccacatggcg gtattgcatt aggattggac cgttttgcaa tgttattagc
    37321 cggagaagat aatattcgtg aagtcattgc ctttcctaaa aacggaaaag cagcagatgt
    37381 gatgagtgat gcaccaagta tggtttcgcc tttacaattg ttcgaattga atattgatgt
    37441 aacgaatata gaagaatagc cgataaaaag gtaaaaagga tttgtcgaat acgcttcttt
    37501 tgacaacctt gatttaattg aaaaacactt tataatgaag ccataacata taaagcgggg
    37561 cttttccatg aaaaaaacat tcgaaaattg ggcttatcat gattacacga ccaagctttc
    37621 ggtatctatc gtttatgcgt tgatcgcatc agtcgcattg aatttctttt atcagccagg
    37681 acatatttat tcaagtggta ttactggtct agctcagatt ttgacgactt tgtcaaaatc
    37741 actgatagga ttcgaagtac cggtatcaac aactttgtat ttactgaata tacctttgtt
    37801 tgtattggcg tggttaaaaa tcgggaagaa gtttacaatt ttcactttta tcacagtcac
    37861 tttgacctcc ctttgtatcc atattttacc ggaaacagtc ctatctaccg atccaatcat
    37921 ctgtgcgttg tttggggggg ctgtgatggg actaggtatt gggctagcgt tgagaaacgg
    37981 cctatcatcg ggcggtctag atatcgtgag tatcacgatt cgtaaaaaaa caggaaagtc
    38041 gattggttct atttcgatct acttcaatgc attgatcgtt tttgttgccg gaattctatt
    38101 tggctggcaa tatatgtttt acagtacgtt gtctattttc gtcagtggaa aagtaactga
    38161 tgtcgtttat actaaacaaa agaagatgca ggtaatgatc gtaacgaaac atccagaaaa
    38221 agtagtaaat gaaatccaaa actgtatgcg tagagggatc acgatcatca atgaagcaga
    38281 aggtgcttat aagcatgata agcagacagt attgatgacg atcgttacac gatacgaact
    38341 gcctctactt agagaagcaa tgaaagcttc tgatccacaa gcttttgtaa gtattgcaga
    38401 aaacgtccag atacttggtc gtttctatga ggatggcatt tagatcgagt ttgacaaaaa
    38461 ttcatgaaat actgctgtag acagacgttc gtttgtctgc agtttttttc taccatagta
    38521 gaatcagcaa agaaaaactg cttttttatt tgaaattttc ttaaagttga aaaaaagcat
    38581 gtttattttt ttaaatttat gggatgatag aaaaaaatag tagagaaagg acacgattct
    38641 acttgctatt ttcacttaat acccgtatat tacgaatgaa aaaagtttat gaaaagttgg
    38701 aatattgaat ggaaaaacaa aaaaggttaa aaaacagccg ctacatcact gggtttgatg
    38761 ggctccgttc attagctgtg gtgggtgtta tcttctatca ccttctgcca actagtatga
    38821 aaggcggcta tttgggcgtt ccgatttttt tcgtcgtatc tggttatttg atcacggatc
    38881 tgctgcggca ggaatgggaa caaaatggaa aaatcaatat ttggcaattt tatgtcagaa
    38941 gaatgaagag actctatccg gcacttgttt ttatgcttgt gacagcttcg gcttatatca
    39001 ctttgtttca gcgagggctg ttaaacaatc ttcgaggagt tgtggtcagc agcttactgt
    39061 atgtcaacaa ctggtggcaa atcaataacg gtttatctta tttcgatcga tttgctaatg
    39121 agtcaccgtt tacgcatatc tggtctttag cagtagaagg tcaaaactat ttggtttggc
    39181 cgatcttgtt tgtattgttg atggtatttg ttcgtaaaag aaaatggatc ttttatactg
    39241 tgttaggtac atccttcctc tccgccatct tgatgatgat cttgtataca ccaggaggcg
    39301 atccaacccg tgtttattac ggtaccgaca ctcgtctgtt ttctatatgg ttgggaagtg
    39361 cgcttgcgtt tgtttggcca agtacgcgtt taaagaaaaa catcccgaaa caagcgaaaa
    39421 atattctgaa tatcgctgga ggaatctcgc ttttggcact gattctttgc ttcttctttt
    39481 tagatgatca ttacaatttc atctattacg gaggaatgct cctagtgagt ctgttatgcg
    39541 tagtgctagt tgcagtgaca gcacaccccg gagcaagttt gaatcgatgg ctgacaaatc
    39601 cagtatttac ttggattggc aaacgaagct atggcattta tctgtatcag tttccagtta
    39661 tgatttttta tgaagcaaag gtgactgata ttgccgatca tgttttgttg catactttag
    39721 tggaaatcac attgattcta atcatcagtg aactttctta tcgatatgtg gagcgtccgc
    39781 tagcacgttt tgattatggt cgtacattcc aagtgatgaa aggatggttc agcaaaccga
    39841 tcatcagtaa gagcaaacca tgggttgttc caggcacatt acttgtagca attgcactcg
    39901 ttggtttcgt tacggcaccg aaaaacgctg taacagccga tcaaaaacaa ctgcaggcaa
    39961 aaatcgctga aagtaaaaaa ttagcagaag aaaccagaaa caattcagaa aacaccacta
    40021 gttcggttga ccaagcgatc cttgataagt acgagttgtc caaggcacaa gggaataagg
    40081 cacaaaaatt agaactaacg gcatttggtg attcagttat gttggatgct gcaacggatc
    40141 tacaagaact ttatccaaaa gtagtggtag atggagatgt cggacgacaa ttatatgcca
    40201 gtgtaccgta cattgaaaaa ttaaaggaac aagatttgtt gaaagacact gttctgattg
    40261 gactaggaac gaatggctca ttctcggaag ctcagtttga tagtgtgatg gatgcaatcg
    40321 gtgatcgaaa agtatactgg gtcaatgtcc gagtaccgac gaagcgctgg caaaatgacg
    40381 tgaatgcgat gcttgaacag atgacgaaaa aatacgacaa tatgacgctg attgattggt
    40441 acagctacag taatgaccat agtgactggt tttatgatga tcaagtccat ccaaatcctg
    40501 aagggatgac acattacatt cacttagtca gcgaagcctt gctaggagga agttcaagta
    40561 cgaacagcag tgagacaaac gtgacagaat gatagctaca aaaaacttca ggcaaaaaca
    40621 tttgtttttg cctgaagttt ttttatattt accgtgtttt taacattcat atagattcag
    40681 gaagcaaaac ggttgagtgt gtctgtaaat aacgttcttt ttgttttcgg gtgagttttt
    40741 tgaatgcagc ttctgctttt gttgcttcgc ttcttgaaga aaatacttct gcatggatca
    40801 tcttaacagg tcttcttttt tgaagacgag tatatttagc accagtacca ttgttatgtt
    40861 cctctaatcg tctagaaaga tcggttgtat atccaccata aaatgtctga tctttacaga
    40921 ataatacgta aaaataatgt tcatttgcca tagagcatct cacgaatctc tgcagtgtat
    40981 tctccatcca tattgtaagt gatcaatggt ggagcgactt tgaatccgtc taatttgcct
    41041 tctttgattc cttcaactaa caaaatattt gcctcttttc caggttttgg gtaaacaaat
    41101 tggatccttt taggtgcaat tcgatagtct tccatgacct gaatgatttc taagaaccga
    41161 tcaggacgat ggaccatagt aaagcgtcca tttgttttta gtagcttact tgaaatatcg
    41221 atcacttctt ctaacgtcgt atgaatctca tgacgggcga ttgccaggtg tttattaggg
    41281 ttcgttttat ttgttggcag ccctttgaaa taaggtggat tacagacgac taagtcacaa
    41341 gaattatgtc gaacgacaga taagctgtct ttcagatcga tggtgtggac agtcatttgt
    41401 tcatttaaat ggttaagcgc gatactacgt cttgccatgt ctgctagacg aggttgaagt
    41461 tcgatagcgt cgatagccgc ctgggttcgt ttacttaaaa aaagtccaac tgcgccattt
    41521 cctgcacaaa ggtcaacaat cttccctttt ttaggtacac gggaaaagtg agcaagcagc
    41581 acagcatcta aagaaaaaga aaacactttg gaactttgga taatcttgat atcttctgcg
    41641 tataattggt cgattcgttc gtcttcgtga agcatggatt ccctccaaaa tgaaaaaaat
    41701 agtcgtctgt attatactat ttttattaaa aagaaccaag gtggcttgtc aaacctctat
    41761 tttttatgca tactatgacc ataagaaggg aaaggaagag actatgtttt atcgatttat
    41821 gcgcggggta gttcgagtac tattagcctt agttaatgga aatgcccgct atgagaataa
    41881 agaagtttta ccgcaagatg agaattacat actagttgct ccccatcgta cttggtggga
    41941 cccattatat ctggcggtag ctgcagcacc caaggaattc agctttatgg caaaagaaga
    42001 actgttcaaa aatccagttc tgcgatttat attaactcga tccaatgctt ttccagttaa
    42061 aagagaaaat ccaggaccaa gcgtcattaa aacacctgta aagattttga aatcgacaaa
    42121 tttgagtttg atcatgtttc ccagtgggac aagacatgct acagaactta aaggcggaat
    42181 ggcattgatt tccagaatgt ctaaagcgaa aatcgtgcca gctgtatatc aaggtccgtt
    42241 gacacttggg gatctgttca agcgtcagag agtgacagtg cgtttcggcg aaccaatcga
    42301 cttatcagat atcaagaaaa cggataaaga aggtatggcg gagatcgaac gacgaacaca
    42361 agcagctttt gacaaattgg acaaagaagt gaaccctgat ttcaaatatg aagtcaaaaa
    42421 aaaataaaat gataagttta tgcgtgggcg gtcttttgaa tctactgtcc tgttcagttc
    42481 agactttttc aatgaaaacg agggagagac gtcaagtctg ccctcttttt gcgttccaat
    42541 atgtaaaata gaagacaggt gtcatgtaat ggatcaaagt gttataataa ttagaaggac
    42601 attttttgag gtgattgaat gcgtttttta catacagccg attggcatat cggaaaaaaa
    42661 ctacaaggtt atgacttgat tgaagaccag cgtcatgtac tatcttctat actagatatc
    42721 gcgaaagaag aaaaagtaga ggcaatcgtg attgccggag acttatatga taggagtgtc
    42781 ccagctgttg atgccgtaga attatacaat gaattgatgg tcgattggaa tttaaaggaa
    42841 aagatcccga tttttgctat atcaggaaat cacgatagca gtacgagact ttcagcgggt
    42901 acgccatggt tcagttattc gaactatttt ttgcgaacac agctagcaga agcatttgaa
    42961 ccagtcgagt ttaaaaacgt acaatttttc tttcttcctt actttgaacc aattgcagcg
    43021 agattatatt ttgaagatga caatatccga acgatcaagc aagcggtagc caaggtgata
    43081 gataaaatgc aggagctatt tgattcagaa aaaaaacaag tattgattag ccattttttt
    43141 gtaatgggaa gtgtaaaatc tgattcggaa acgaaaatcg aagtaggcgg gttggattcg
    43201 atccctggtg aactacttac accgtttgat tatgtagcac taggacattt gcataatcaa
    43261 gctgctttga gacaggataa tgctcgctat agcggttccc cattgaaatt ctctttatct
    43321 gagatcaacc aaaaaaaagg cgtatggatc gttgacctga caacaggcct ggagttgaat
    43381 tttagggaga tcgaacccct gcatgatatt gaagaaataa cagcgagttt caaagaattg
    43441 ctggatcctg ccttttatca gtccgtcaat cgggagaatt acatctatat ctatctcact
    43501 gatagaacga tcatcccgaa tatgatgaac cagcttcggc aaatatatcc tcgtattttg
    43561 gggattgaac gggcaaacgg tcgagcagaa caaacaaagc gcaaacgaaa agtactagaa
    43621 atgaaagatc ctcaaaaatt agcagaagca ttttttagtg aaatgacgga agagcagcta
    43681 actgcaaacc aagaaaaatg gctcggagaa acgttgcaag aaatcatgga aatggaatga
    43741 tcaagaatga aaccgaaaaa attacaactt aaaaattttg gtccttttat caatgagacc
    43801 gtagattttt cacgtttgac agaagcaccg ctttttttga tcagcgggaa gacaggagct
    43861 ggcaaaacga cgatttttga tgggatcacc ttcgcacttt ttggtgaaac ttccggaaga
    43921 cttcgctctg gaaaagagat gcgttctttg tttgctacac cagacgaaga aacaagcgtg
    43981 actttttctt ttgaacatca gcagatgagc tatgaaatcg aacgaaaacc agaacaagtt
    44041 ttagcaaaac gaaaaggaaa cggaacaaaa aaacaggcag ccaaagtaac gttgaccatt
    44101 tttgatggga aaggaaaaga aataaaacaa atcacaaaac gtacagaagc agatcagttg
    44161 atcagagaac tgatgaatct cgatgcgaaa cagttttctc aaatcgtttt actaccccaa
    44221 ggagaattcc gtaatttttt ggtttcatca agcagtgata aagagactgt tttacgtcat
    44281 ttattcggta ctcaattttt ccaacagttc aatgagcgat taaaagaaaa agcaaaacaa
    44341 cagcaacaaa aattggatca tttagagcaa gagctgcatc ttctgcaaaa aaggtttgtt
    44401 ttagtcaaag aagaggaacc agcagcaggg tttgaagccg ttttagccca atggacaaac
    44461 catcaggcaa tactcgaaaa acaaatcacg gaagaaaaag aagctctaac ggaacttcag
    44521 gaaaaacaaa agcaactaga aaattcctac tatcgttttg aaagcttgaa aaaaagttat
    44581 gaagaaaaaa cgatattaat aaacaagcaa aaggaattag ctgctcaaaa agacgaaata
    44641 gaggaaaaga aacgatggat tgggtattat gaatttacgc aacgattagt cgaaccaatc
    44701 cagcgcctac aagaaataaa agttgaaaaa atagaactgt cacaaaaaag tagtgagcaa
    44761 acaaagaaac tagcgatgac tacgcagaat tatgaagagt ggcaaaaaaa tgaagcaaac
    44821 cgcgtacgcc gacaaacaaa aatcaaagaa gctgctcaaa aactgcaaaa caaacagatg
    44881 atggtgccaa ttgtcgaatc cttacgtagt aaaaaacaag acgcagaaca attaacaatt
    44941 tcattggata aagaagaatt gaatgccgag aagctgtatc aaaatctcgc tatctatcag
    45001 gaaagaactc gaattcttca agaaaattta ctggatcagg aaaaactgca agaagatcgt
    45061 cttgcttttg gacagttaaa atatctagat gaaaagcagc aagaaataga aaaacaaaaa
    45121 gcaaaagaca ctgggtcgct cgcacagata agagaagaac tcaaaaaagc aactgaagaa
    45181 ataacaaaaa atagtcagct attgaaagaa cagacagaac aagcagaaca gctgaaaagc
    45241 caatgggcaa agcagcaaat tgctcgtctt cagctttttt tgcgtccagg ggagccatgt
    45301 cttgtttgtg gatcaacgga acaccccata caacaattaa aacacgaaca gccaaataag
    45361 gaagatatct taaaagtaga acaacaactg gcagaagctg agtctgctgt agaaagaact
    45421 cagcaaatca ttgccaaaag tgaagcacat gaaaataatc ttcaacaaca attatcagat
    45481 ttagaacaaa aaatcatggc aacgaatata caattggctg aacaagaaga acacttgcaa
    45541 caggctttga aaaaggcatt tcctgagata acagaacaaa aaacaaaaac aactcttgta
    45601 gtaatcgaac aatctttaga tagacgaaaa agcaagatgg ccaatgcaag aatagagctg
    45661 gaagaaataa gacaacaagc agaaaagctc gaacaacaat tagctgtcta caaacagcag
    45721 cagacagaaa aaaataatca gctccagcaa ctgcaaggag aaatcaaaag tttagaacaa
    45781 caattgcaag atacggatag taactgttta gaagaggaga tacgacgact tgaaaaacag
    45841 ttagaagaag actcgaatca actagctgtt gagcagaaag caggagtgca attgttgcaa
    45901 gatcttcata cgcttcggac acagcttgat cttcaacatg aacaaataga aaaaatagat
    45961 gaaaaaatag aaaaggaaca agaaagaata gctaaaaagt tagaaagcca gtcgtatttt
    46021 tcaacaattg aagaaatctg tgcatttgca caacagcaag cacaatataa agaaaaccaa
    46081 cgtacagtta cttcttatca tgaagagcaa ttagtgacag ctgaccggct gcgtcaatta
    46141 gaaaatatcc agctaactga gacattccca gatacagaag agatcagcca acagttagaa
    46201 gaaataagac gtatgatcga aataaagcaa gaaaagatat acggtttaca agaacaaaaa
    46261 attagtaatc aaaaaatcta cgatgaatgt ctttcgattt atcacacaag ccagacgaaa
    46321 ttagatgagc ttacgcaatt acagcagctt tcgcaaacat tcaacggaga aaatcctaag
    46381 aagactagtt tggaacggta tgtgcttcag gtttatcttc aagaagtgtt acaagtagca
    46441 aatgatcatc tccaacgttt aacgaaaaat cgttatcaat ttgagctagc ggataccatt
    46501 ggcagttatc gagggaaaac cggattagaa atcaatatct atgatgatca ggcaggtatg
    46561 tctcgaagtg cgcataccct gtctggcggt gagagtttta ttgcagcact ttctttagca
    46621 ttagctcttg ccgatgtgat ccagacacaa gctggtggtg tagcaatcga tgcattgttt
    46681 attgatgaag gatttgggtc attagatgaa gaagctttgg aaatggcaat ggaagcttta
    46741 gaaacgatcg aaagtgaagg aagaatgatc ggcatcatta gtcatgtaag agaattgaaa
    46801 gaacgagtat tacaacaaat aagaattgat acagaaggta gcggacaaag caaaatacgc
    46861 tatcaacttg gataaaaagg gagattggta actatgaaat ggagtattcc agaaaaagtc
    46921 attgcacgtg gacgtcaata cttgcaagaa ggccgagtgt tatcggttgt ccctgaccaa
    46981 gaagaaaacg tgtggcatgc agaagtcttg ggcagtgaat tgtatatggt tgatttggat
    47041 ggtacagcaa aagagataga ttactgccaa tgtccctatt gggaggaaca taaatattgt
    47101 aagcatacag ttgctgtgga actttattta cggtcgaaaa atctatctcg tatcatgaaa
    47161 aaagaccagc caatgctaga accggtaaaa gcaacaagtg agggagaaat cattgcaaaa
    47221 ggtttttctc gtctaaaaac acaaaacaat cctcaagcgg tgcaaccttt gattattgaa
    47281 taccaagtag aaacgattga gactaatcag tatcacccag agctttctat tttggcactt
    47341 tacttgcgta tcggttcatt ggcatcaccg aaaaaaacat atatcgtaaa aaacatctat
    47401 gattttttac aagcttacac agaaaaagaa acttacactg ttaataaaca gtaccagttt
    47461 cgtctagata aacgggcgtt tcaaaaagaa gatcaaaaaa tactcacgca tcttgcagga
    47521 agtgctcaga cgcatcaatt attaggtacg aacggcttac aagtcaaagg aaaactagat
    47581 aaaagatatc tgcttctccc agtagaacaa gcccgcttcc tgttagagca gatgaatcag
    47641 actacacgtt tgcatctgca gataaatgaa caaaacgatc aaggaataca attttccgat
    47701 caaaacaaac ctttatcatt caaagtggaa aaatttggag aagattattt gctgcaagca
    47761 ttgaatgatt ttgatttttt ctttatgcat tatcagtggg gagttatcca agggacattt
    47821 tattctctga cgaaatatca acaaacggtt tatcaaactt ggaaacaatt gattcgccga
    47881 ttggagaaac cagaagtagt gttcaagaaa aaagaattac cgtctttgtt taaagagatt
    47941 atccctctgc tgtcagagat cggcgacgta gctattgccc ctgcagtaga agaggaagta
    48001 gcagatatcc ccgtcgaatt tattttcttt ttccgaaaag caaaaggaaa aatccaagct
    48061 cgagtcgatt tcgtctatgg tgaagtcatc tattcgactg acccgaagca tgaggtctcg
    48121 acagaacagg cttttcaggt gttacgtgac acagtagaag agaaacgagt acttgatcta
    48181 ttcagaatgt atcgctacca gaaaaatgaa actggttatg aacgtccatt gccaagcggg
    48241 gaagaactat atgccttttt ccgcacagaa ctatctgtct tccgtcagtt tggtgaagtc
    48301 agacttggaa gaaaattgcg agagttgtat ttagatgcgc ataaacatca accgaaaatc
    48361 gaagtaaccg agaccggttc atggctcgat attcgattcg atgtgacagg gatagaggag
    48421 caagaaatcg atcatgtcct gcaaagcttg ctgagaaatg atgcttttta tacattagaa
    48481 aatggtcagg ttctttcttt tgattcagaa gaatttcaac aaacaagcca agtgttgcaa
    48541 caattacggg aatcgatacg tacagaagaa ggaacgatcc atgtacctaa aaatcaagga
    48601 ttgatcattc aaaatcaatt ggaaaaaagc aatgctactt ttagtgaatc gttccaaacg
    48661 atggtacaag atctcattca tccagaaaga taccaggcac agcttcccaa aggattgaat
    48721 gcaacgatga gagattatca aaagcaaggt tttcgatggt tgaagatgtt aggtcattat
    48781 cagtttggcg gtattttagc cgatgaaatg ggacttggga aaacactaca gacaattgcc
    48841 tttttacttt cggaaaaaga agaacggaaa agcttctctg ctttgatcgt agcgcctgcg
    48901 agcttaattt acaactggca ggcagaggtg agaaaattcg ccccttcttt aagtatccaa
    48961 gtaatcaatg ggaataaaaa agaacgtgaa gaattactgg ctaaagacac agatatccga
    49021 gtgacttctt atgccagctt aagacaggat ctagctaatt atcagtcgca aaaaattgat
    49081 tatttgattc ttgatgaggc acaaatggtc aaaaatagca gtacgaaaac tgcacaagca
    49141 ttgagagaat tagctgtacc tcagcggttt gcactgagtg ggacaccaat cgagaataat
    49201 ttagaagaat tgtggtcatt gtttgcaacg attatgccag gatttttccc gactaaaaca
    49261 aaattcaggg aacttgccgc agaagaaatt gcgcaaatga ttcgaccgtt tattttacgg
    49321 cgagataaac aaactgtgtt gaaagacttg ccggaaaaaa cagagatgaa tctatattct
    49381 gcacttacag aagaacaaaa aactgtttat ttagcttact tgcgtcaaat gcgtgaagaa
    49441 atcacatcaa tggattctga agcattcaag aaaaaccgga tcgggatact tgctggtctg
    49501 acaagactgc gacaaatttg ctgcgatcct cgtctgttta ttgaagatta ccaaggcggt
    49561 tccggcaagc tcgaacaagt aaaagatcta ctggtagctg ccaaagagaa caaacgaaga
    49621 gttttgctgt tttctcaatt tacagggatg ctgactatct tgcaagaaga gttagccgag
    49681 ctagggatct cgacatttta tttaagaggc agtacgaaac cacaagatcg gttaagtatg
    49741 gtagacgcat ttaatgctgg cgaaaaagat gtttttctga tttccttaaa ggctggggga
    49801 actggattga atctcacggg agcagatacg gtcatcttgt atgacctttg gtggaatcct
    49861 gccattgaag aacaagctgc tggacgtgca catcggatcg gacaaaaaaa tgtggtagaa
    49921 gtgtggcgta tgatctctga aggaacgatt gaggaacgca tggattcact ccagcaagaa
    49981 aaacgcgaac tgttccaaaa agtgatccaa ggtaatgaag aacagttgac gaaactgact
    50041 gaagaagaca tccgcatgat tttaagtgta ggagaaatcg aggagtaaga gactcgaaaa
    50101 agcgttcagt aatgggtaag aaagcctttc taaagaagcg attgtttatt tgatttaaaa
    50161 aatagcaagg aggctgggat tccattttat cccagcttcc ttgctatcat ttttttattt
    50221 ctatttttaa aggttataca aagattgtct tcattgtctc taacagctga tcaaaagaag
    50281 aaatctcgat atcgcaaatt ggagtctgtt caattttgcg ttctcgatgg ttgaaccaaa
    50341 gcgcttgcca gttagcactt tttgcaccta gaacatcatt gtcgtaatta tcgccaacgt
    50401 ataaggtctc ttctggaagc atatgaaatt ctttctcagc cagctgaaaa atctcttttt
    50461 ctggtttttg gaaacctgtt gcttgagaaa tgagcatatt gcgggaagga atccaattgt
    50521 tcaattgaag ttgcttcagt ttttttgtct gatggtcagt cggcccattt gtgataattc
    50581 ctaatgggac attcttttcc ttcaagaaat cgagggtttt tttgacctcc tcatgcaagc
    50641 agatattatc aagttcttcc tcgtaaattt tttgaaataa gaggccatct tcttccgtaa
    50701 tatgagggta gtctaaatct tttagtgatt ggctgatccg atgtgctcgc atatattcta
    50761 gtgtccaatc tcctgccatt acttttggga agttttcatc actatgatgg cggaaccgga
    50821 tatatagtgg atgcatatct gcatctgaaa caagcggaac gactcttttg accgcgtttc
    50881 gaaatggctg ctgctgatca tacatcgtat catcaacatc aaacacaact gatttaatca
    50941 aaattttaca cgcctttcgg ttttcattga ttttttcaca aatccttgac tattgtaaca
    51001 gaaaaaattg tctaaaaaag ctgataaata aaggtttttc ttactatatt tctatttcct
    51061 tgacagaata aggtttttat atttcagttt ttttcactaa aaatcgtgaa acacgtcaat
    51121 aagtttgatg aacaaattaa tcattatggt agaagtcgat tgatttattt taatgcaatc
    51181 tctgtggaat tttcgaaaga tttatttttt taatacagtc tcaatataac tattcaaaca
    51241 taaaataacg ttatttgatt tatttgttta tagtaaattt tatttagtaa tcattgcttt
    51301 aaaatactac gcttatataa cagagaaaat aagcgttata ataaagaacg gtattattta
    51361 aaatgacaga aaacattact attaaagaaa taaaaaacat aaaaaatctt aagaaatcgg
    51421 tttcatttag cttttgagat aaaataatag tacagtttta tacgctgttt catatgttta
    51481 gaaaatttga attagatttg aaaactctaa tttttaaatg ataaaaaaag cgagaatgct
    51541 ggttttactg tatattaacc ttagataact ttcatttttt taaaaaaatt atgaaaaaaa
    51601 ggtagctatt taaaagttga ttatgtataa tagaaacaga tgggagatta ttatgatctt
    51661 ctgttacaaa aaagtgattc ttatcacgaa aaggagtggt gcacgttgtt aacattatat
    51721 acttccccaa gttgtacttc ctgcagaaag gctcgtgcgt ggttgcaaga acatcagatt
    51781 ccatttgttg aacgtaatat tttttcagaa ccattgaaca gttctgaatt aaaagcgatt
    51841 ttacaaatga cagaagacgg aacagaagaa atcatctcga cacgttccaa agtattccaa
    51901 aaactgaaca tggatttaga tgatctgccg ttacaagaat tattggaact tgtgcaaaac
    51961 aatcctggat tgcttcgccg tccaatcatg attgatgata aacgtctgca agttggtttt
    52021 aatgaagatg aaattcgtcg gttcctaccg cgcgatgtac gacaattaga attacgtcaa
    52081 gcacaattga tggctggatt atagaaggat aatacgaaac ttggaaaaga
//
LOCUS       DBBGRF010000018        49672 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000018 DBBGRF010000000
VERSION     DBBGRF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 49672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.018"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            257..532
                     /locus_tag="ACIZD4_001134"
     CDS             257..532
                     /locus_tag="ACIZD4_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990083.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            545..2623
                     /locus_tag="ACIZD4_001135"
     CDS             545..2623
                     /locus_tag="ACIZD4_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGC5990084.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2786..4669
                     /locus_tag="ACIZD4_001136"
     CDS             2786..4669
                     /locus_tag="ACIZD4_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC5990085.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            4681..5628
                     /locus_tag="ACIZD4_001137"
     CDS             4681..5628
                     /locus_tag="ACIZD4_001137"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGC5990086.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5648..6175
                     /locus_tag="ACIZD4_001138"
     CDS             5648..6175
                     /locus_tag="ACIZD4_001138"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGC5990087.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6238..6891)
                     /locus_tag="ACIZD4_001139"
     CDS             complement(6238..6891)
                     /locus_tag="ACIZD4_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGC5990088.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7023..7865
                     /locus_tag="ACIZD4_001140"
     CDS             7023..7865
                     /locus_tag="ACIZD4_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGC5990089.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8023..8919
                     /locus_tag="ACIZD4_001141"
     CDS             8023..8919
                     /locus_tag="ACIZD4_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGC5990090.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8922..9635
                     /locus_tag="ACIZD4_001142"
     CDS             8922..9635
                     /locus_tag="ACIZD4_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HGC5990091.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9655..10173
                     /gene="msrA"
                     /locus_tag="ACIZD4_001143"
     CDS             9655..10173
                     /gene="msrA"
                     /locus_tag="ACIZD4_001143"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HGC5990092.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQDYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10170..10397
                     /locus_tag="ACIZD4_001144"
     CDS             10170..10397
                     /locus_tag="ACIZD4_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGC5990093.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10549..11100
                     /gene="lepB"
                     /locus_tag="ACIZD4_001145"
     CDS             10549..11100
                     /gene="lepB"
                     /locus_tag="ACIZD4_001145"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGC5990094.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11183..11725)
                     /locus_tag="ACIZD4_001146"
     CDS             complement(11183..11725)
                     /locus_tag="ACIZD4_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HGC5990095.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(11962..12360)
                     /locus_tag="ACIZD4_001147"
     CDS             complement(11962..12360)
                     /locus_tag="ACIZD4_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC5990096.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12620..13480
                     /gene="ylqF"
                     /locus_tag="ACIZD4_001148"
     CDS             12620..13480
                     /gene="ylqF"
                     /locus_tag="ACIZD4_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGC5990097.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13473..14240
                     /locus_tag="ACIZD4_001149"
     CDS             13473..14240
                     /locus_tag="ACIZD4_001149"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGC5990098.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14296..15153
                     /gene="dprA"
                     /locus_tag="ACIZD4_001150"
     CDS             14296..15153
                     /gene="dprA"
                     /locus_tag="ACIZD4_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGC5990099.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15275..17353
                     /gene="topA"
                     /locus_tag="ACIZD4_001151"
     CDS             15275..17353
                     /gene="topA"
                     /locus_tag="ACIZD4_001151"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGC5990100.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17322..18698
                     /gene="trmFO"
                     /locus_tag="ACIZD4_001152"
     CDS             17322..18698
                     /gene="trmFO"
                     /locus_tag="ACIZD4_001152"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HGC5990101.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18896..19801
                     /gene="xerC"
                     /locus_tag="ACIZD4_001153"
     CDS             18896..19801
                     /gene="xerC"
                     /locus_tag="ACIZD4_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HGC5990102.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19838..20386
                     /gene="hslV"
                     /locus_tag="ACIZD4_001154"
     CDS             19838..20386
                     /gene="hslV"
                     /locus_tag="ACIZD4_001154"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HGC5990103.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20400..21800
                     /gene="hslU"
                     /locus_tag="ACIZD4_001155"
     CDS             20400..21800
                     /gene="hslU"
                     /locus_tag="ACIZD4_001155"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HGC5990104.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21818..22609
                     /gene="codY"
                     /locus_tag="ACIZD4_001156"
     CDS             21818..22609
                     /gene="codY"
                     /locus_tag="ACIZD4_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGC5990105.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22691..23566
                     /locus_tag="ACIZD4_001157"
     CDS             22691..23566
                     /locus_tag="ACIZD4_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HGC5990106.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(23698..24336)
                     /gene="plsY"
                     /locus_tag="ACIZD4_001158"
     CDS             complement(23698..24336)
                     /gene="plsY"
                     /locus_tag="ACIZD4_001158"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGC5990107.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            24463..24897
                     /locus_tag="ACIZD4_001159"
     CDS             24463..24897
                     /locus_tag="ACIZD4_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGC5990108.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25063..27108
                     /gene="parE"
                     /locus_tag="ACIZD4_001160"
     CDS             25063..27108
                     /gene="parE"
                     /locus_tag="ACIZD4_001160"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGC5990109.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            27120..29570
                     /gene="parC"
                     /locus_tag="ACIZD4_001161"
     CDS             27120..29570
                     /gene="parC"
                     /locus_tag="ACIZD4_001161"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGC5990110.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            29847..32078
                     /gene="pflB"
                     /locus_tag="ACIZD4_001162"
     CDS             29847..32078
                     /gene="pflB"
                     /locus_tag="ACIZD4_001162"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGC5990111.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            32322..33083
                     /gene="pflA"
                     /locus_tag="ACIZD4_001163"
     CDS             32322..33083
                     /gene="pflA"
                     /locus_tag="ACIZD4_001163"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGC5990112.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            33168..34094
                     /locus_tag="ACIZD4_001164"
     CDS             33168..34094
                     /locus_tag="ACIZD4_001164"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGC5990113.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            34276..35169
                     /locus_tag="ACIZD4_001165"
     CDS             34276..35169
                     /locus_tag="ACIZD4_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HGC5990114.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            35303..35428
                     /locus_tag="ACIZD4_001166"
     CDS             35303..35428
                     /locus_tag="ACIZD4_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGC5990115.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(35562..36194)
                     /locus_tag="ACIZD4_001167"
     CDS             complement(35562..36194)
                     /locus_tag="ACIZD4_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990116.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(36342..36884)
                     /locus_tag="ACIZD4_001168"
     CDS             complement(36342..36884)
                     /locus_tag="ACIZD4_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HGC5990117.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            37019..37408
                     /locus_tag="ACIZD4_001169"
     CDS             37019..37408
                     /locus_tag="ACIZD4_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990118.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            37412..38176
                     /locus_tag="ACIZD4_001170"
     CDS             37412..38176
                     /locus_tag="ACIZD4_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC5990119.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            38305..39252
                     /locus_tag="ACIZD4_001171"
     CDS             38305..39252
                     /locus_tag="ACIZD4_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5990120.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            39382..40122
                     /locus_tag="ACIZD4_001172"
     CDS             39382..40122
                     /locus_tag="ACIZD4_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990121.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(40413..41081)
                     /locus_tag="ACIZD4_001173"
     CDS             complement(40413..41081)
                     /locus_tag="ACIZD4_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC5990122.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            41215..41502
                     /locus_tag="ACIZD4_001174"
     CDS             41215..41502
                     /locus_tag="ACIZD4_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990123.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            41918..43456
                     /locus_tag="ACIZD4_001175"
     CDS             41918..43456
                     /locus_tag="ACIZD4_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGC5990124.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            43453..44418
                     /locus_tag="ACIZD4_001176"
     CDS             43453..44418
                     /locus_tag="ACIZD4_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990125.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            44405..45727
                     /locus_tag="ACIZD4_001177"
     CDS             44405..45727
                     /locus_tag="ACIZD4_001177"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC5990126.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      45790..45894
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            45968..46711
                     /locus_tag="ACIZD4_001178"
     CDS             45968..46711
                     /locus_tag="ACIZD4_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990127.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            46726..47718
                     /locus_tag="ACIZD4_001179"
     CDS             46726..47718
                     /locus_tag="ACIZD4_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5990128.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            47730..48467
                     /locus_tag="ACIZD4_001180"
     CDS             47730..48467
                     /locus_tag="ACIZD4_001180"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990129.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            48457..49179
                     /locus_tag="ACIZD4_001181"
     CDS             48457..49179
                     /locus_tag="ACIZD4_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGC5990130.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(49263..>49672)
                     /locus_tag="ACIZD4_001182"
     CDS             complement(49263..>49672)
                     /locus_tag="ACIZD4_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HGC5990131.1"
                     /translation="QLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEKQAAP
                     VAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYLNGDY
                     SAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        17143 a         8505 c        10407 g        13617 t
ORIGIN      
        1 tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca ggaatgggaa
       61 agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga tatctgatac
      121 tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag caataaacga
      181 tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg aagtttgtgt
      241 ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt tgcatgatcg
      301 ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc gtaaaagaaa
      361 tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt tggagtcaaa
      421 acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg aaaccaaaat
      481 tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat aaaggggatg
      541 gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct tatcgaacat
      601 agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc ttggagtggt
      661 attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt tcttagttat
      721 gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt cgattctcaa
      781 aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc ttgtcggggt
      841 aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct ttgcttttgg
      901 agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac gagtgaatat
      961 ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg catctggtgt
     1021 tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag cagtaaacgc
     1081 ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt tgcttgtctg
     1141 gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg tcacagggta
     1201 tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg catttgatgt
     1261 atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt ttaggaaaat
     1321 ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa ctattgcttt
     1381 tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag tgttctcgcc
     1441 agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg tattaatctc
     1501 tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat tcaaagatgg
     1561 cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg gcggtgtaaa
     1621 gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata atatgatgtt
     1681 ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga ctttggtcat
     1741 agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca cggatttgaa
     1801 tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa aggaaattga
     1861 tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc aagaacggat
     1921 acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac aagaaataca
     1981 agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt cgggcaagct
     2041 ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac attctatcac
     2101 aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt taatgcgaat
     2161 cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga catttattag
     2221 tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt tgattattga
     2281 aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt ttatccagca
     2341 acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt ggatgatcca
     2401 gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat
     2461 tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct atcgcaggaa
     2521 tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt ctttccgatt
     2581 tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta aaaattttca
     2641 agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt ctttttttga
     2701 gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt ttatgataca
     2761 atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac
     2821 ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa aagaccgtat
     2881 cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta ttgccggtat
     2941 cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc gtattggtta
     3001 tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag tctttcaagg
     3061 aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg aactagggga
     3121 aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa
     3181 agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat taggaatcag
     3241 tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag ttagtctggc
     3301 gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa accatttaga
     3361 ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg cactattgat
     3421 ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg aactttcatt
     3481 tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa aagcagaacg
     3541 tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac aggaattagc
     3601 ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga tcaaccgttt
     3661 cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag agctgaacct
     3721 agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt accgtataaa
     3781 tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa gactaggtat
     3841 tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg gcagaattcc
     3901 cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt atacacaaga
     3961 aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag ctgctgaaga
     4021 agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac gatttttatt
     4081 tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa aacgccggtt
     4141 atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg aaccgaccaa
     4201 tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt ttccaggtgc
     4261 tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata agttattagt
     4321 attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt atttactgaa
     4381 gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc
     4441 tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga ttgaagatga
     4501 gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc atcaaggaga
     4561 taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag cacaacttga
     4621 agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg aggaaaaagg
     4681 atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca tcgtaaagaa
     4741 gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt tgatctgcaa
     4801 aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa aagcgaattg
     4861 ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa aaaccatatt
     4921 tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg accagatatg
     4981 actgattttg gccatagatg tttgacagat cctgaattca atgaagaata taaaaagcag
     5041 agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac atacggcgat
     5101 cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg tggctttatc
     5161 gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag aagattgatc
     5221 gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg tcatacgatg
     5281 tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg cagtggggat
     5341 gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca cctaattgca
     5401 catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc tcatctttat
     5461 atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc atttccgact
     5521 ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga tatccaatta
     5581 gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa tcagaaagga
     5641 tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg gaaaagaaga
     5701 ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga cagaagcaaa
     5761 tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt tgccgaatcg
     5821 tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc atgtcatgca
     5881 tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt tcatcgctgg
     5941 agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc gtacagtcat
     6001 ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg attggtcact
     6061 gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc aatttgaaac
     6121 gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga tataaaaaag
     6181 ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt ttttttatta
     6241 agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa acaaatgcca
     6301 aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta tcgtgtaaga
     6361 aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat aaagaggaac
     6421 agcagccacg acacagagcc accccataaa aatatagatg atcgtagata cttttgatac
     6481 tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg caaacaacca
     6541 gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac aaaaaggagt
     6601 ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga acaccttttt
     6661 tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa gaatcatcat
     6721 cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg caccttttac
     6781 taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg tgactgcatt
     6841 aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca tgaaaacggc
     6901 tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta aaaatagaaa
     6961 ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag agagagaaaa
     7021 taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa aatgtacgcg
     7081 atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca gtatatcccg
     7141 atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca aaaaatctgc
     7201 ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag ctaggagaag
     7261 acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca gtagaagcag
     7321 caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt gataccactg
     7381 accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa ggtaaaacag
     7441 tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta tacatcggaa
     7501 tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact ggtttgctgt
     7561 ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta atccctgtaa
     7621 ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa aatgaactga
     7681 aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa gaattggcgc
     7741 aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct gtactgcata
     7801 cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg tattatgtag
     7861 attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt ctctttttct
     7921 ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt ttgataaaat
     7981 ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt aacgaaacga
     8041 catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc aggtttagct
     8101 gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag agaagatcca
     8161 aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga aggagtagga
     8221 gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa agaccgttat
     8281 aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag tgaccagatc
     8341 ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc tgattttatc
     8401 acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt attcgggtta
     8461 acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac agaactattg
     8521 gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat ctacaatcca
     8581 ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa ttggaacaaa
     8641 ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat caatgatttg
     8701 ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga tcaaacaact
     8761 agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga agatcatttc
     8821 catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca gctgatcgag
     8881 acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca agatctgacg
     8941 tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt atccttcttg
     9001 gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat cgggaaccag
     9061 aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta acgatcaatt
     9121 caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat caaaaagata
     9181 gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt actttcgaag
     9241 tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg gaaaacggaa
     9301 atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca atcaaagatg
     9361 tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc aatacagatg
     9421 atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg tatattaaag
     9481 cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg ccaaaagata
     9541 cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt actgaaagca
     9601 agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat cataatggaa
     9661 cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga cacgcttcct
     9721 ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc gacttatgaa
     9781 caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta tgatccaaca
     9841 ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc aactgacgct
     9901 ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta tttgacagaa
     9961 gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg acgtttcgaa
    10021 cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga agaagaccat
    10081 caagactatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg ccgggctgcc
    10141 tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat tatttaatga
    10201 cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa gccggtaaag
    10261 acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat ctggaactga
    10321 atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa tatttagaaa
    10381 ataatcatga catataagag atagttttgt actttatgat caaaaaagtt ttttgtccaa
    10441 tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt ttgatatttt
    10501 tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt gacaaaaaaa
    10561 caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc tgtattcctt
    10621 gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa ttcaatggaa
    10681 aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat cagacgattt
    10741 gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt aatcggtctt
    10801 ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa agtagttaag
    10861 gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta tacgacggac
    10921 tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta ttttgtactt
    10981 ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa taaaactgat
    11041 attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg gatccagtga
    11101 gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat ccaaaatcag
    11161 tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta gcctctaaag
    11221 ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata ttcctgatga
    11281 atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc agccaagaat
    11341 tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg gaaggcaggt
    11401 ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa gccgtgataa
    11461 gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg ttcgacaaca
    11521 tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc atacttaaaa
    11581 atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag atgacatcaa
    11641 gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc aatctaaaaa
    11701 cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat aataaaagga
    11761 taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact ggcatctaac
    11821 aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat tgtacgaata
    11881 aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt tgttataaaa
    11941 aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg tatttccgtc
    12001 tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat ctacttcgtg
    12061 gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat ccgcattttc
    12121 aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt ctttatcttt
    12181 tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt catcccatac
    12241 cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca gcttttcata
    12301 aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca tactattcat
    12361 ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa acgctgtcaa
    12421 aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa aagtgaagat
    12481 gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt ctttataata
    12541 aaaaagtgaa tttatattga aaaagaaaaa aacaagtaaa gccggggaat attccggtat
    12601 gaaaggaatg gagagaacaa tgaccatcca atggtttccg ggacatatgg caaaagcccg
    12661 acgagaagtt tctgaaaaaa tgaaatatgt ggacatcgta tttgaattgg tagacgcacg
    12721 attaccttta tcttctcgta atccaatgct agatcagatc attcagcaaa aacctcgcct
    12781 tgttttattg aataaagcgg atctggcaga tccacaacag acaaagctgt ggcaagaata
    12841 ttttcgtaaa caaggccatc ttgcattagc tatcacggca caagaaagta aaggaattaa
    12901 aggtctagta cctgcggcta aagaagcatt gaaagaaaaa cgggcaagag atgctgctcg
    12961 ggggatcaag cctcgcgcta ttcgggcaat ggtcttaggt attccaaatg ttgggaaatc
    13021 tacgttgatg aatcgactag taggcaagaa aattgcacag acaggaaata agcctggcgt
    13081 aacaaaaggt cagcagtggc ttcgtttagg taatgagttg gaattgttag acacaccagg
    13141 gattttatgg cccaaatttg aagatgaaga aatcggcaaa aaactagcgc tgacaggcgc
    13201 gatcaaagac cagcttgtcc atttagatga tttagcgatt tacggattag acttttttgc
    13261 ccgatattat tcaggaagaa tcagcgatcg ttatggttta tcaatcgagc aagaagaaaa
    13321 attggcaccg gaattactga tggatattac agcaaaacgt gggtataaag aagactatga
    13381 tcgtggcagc gaattagtcg tgcatgatat tcgtcaagga aaacttggac gatacacact
    13441 ggatcgttgc gaagaaatgg agcaaaaaag tgatgactga atccatccaa agtatcaaag
    13501 aacgattgaa aagcatacag agaatagatg atcctacact agaatcatta agaaatgatc
    13561 cacgcaaagg cgtgcagcaa gcactggctt cttttgaacg acgattgaaa aaggaagcat
    13621 taattaagga aaaatatgaa gaaatgtttt gctttgaaaa gcaagggtac gcacaaggtc
    13681 accaatggat tgccggcatt gatgaagtag gaagaggacc attagctgga cctgtcgtgg
    13741 cagctgcagt tatcttgccg aaaaatgaga tcatattagg gctgaatgac tccaaacaat
    13801 tatcagagaa aaagcgagaa cttctttatc aacaagttca agaaaaagcc ctggcaatcg
    13861 ggatcgggat cgttgatcag cagacaatcg atgatgtgaa tatttatgaa gcaagtaaat
    13921 tagcgatgat ccaagcagta gaaaaattgt ccattgtacc aagctatttg ttgatcgatg
    13981 cgatgacctt ggatttgcct attcagcagg aaaaaataat caaaggggat gcacgatctg
    14041 tgtcgattgc tgctgcaagt atcattgcta aagtatatcg agaccaattg atgaaagaat
    14101 atgacgtgct ttatcctgga tatggtttct cgcataatgc aggttatgga acaaaggaac
    14161 acttagaagg acttgaacga caaggaatta cgccaatcca tcgtaaaagt tttgcacctg
    14221 taaaaaaata tttacaataa aaaacagccg cttttacgta tcttattaga aagagagacg
    14281 aaaggcggtt ttatgatgta tcaaatagaa gaaaatttat tgaaacttgc ttatacaaaa
    14341 ggaatcagta gtcaaggaaa atgggcactt gctaactgga tgatgcagta tccttataaa
    14401 gaaatcggat ttgaagacat cattaagata ggtaaaataa ccaaacaccg ggagctgttt
    14461 cgcaaaagtt ggcaggaaat tcacgctaac tggggcaaaa tccaatcgaa acagtcgttt
    14521 atcacttgct ttgatcccaa atatccccct cagctgcttc acttgaccta tccgccaatt
    14581 gtactgtttt ataatggtga tctatcttta ctttcttgta acatgttaag cgttgttggt
    14641 ggaagacaca cttctgcttt agccaaaaaa acagtttatt atttactaaa accagtgata
    14701 gaagctggat atgtgatcgt cagtggctgc gcgaaaggga tagatacata cggtcaccaa
    14761 gcagcaatct ctcatggtgg acggacaatc gcagtcattg gaacagggat agagcaagtc
    14821 tatcctgctg aaaatcgtga cttgcaagag gtgattgcaa atgatcatct tcttttgagt
    14881 gaatatcctc ctcaatccgg cccgaaaaag cattgttttc caatgagaaa tcggattatc
    14941 gcagctttgt ctaaaggaac atgtgtcttt gaagccaaga aaaaaagcgg ctctctgata
    15001 acagcacagc aagcattgga tcttggaaga acagtttttt ctgttccagg aaatatttta
    15061 acagaacatt ctaccggatg tcatcatttg atccaagacg gtgcagtttg cacggtttcg
    15121 ggtgaagata tcttggcaga atttaaagaa taacaccata cttttcattt gcttttcttg
    15181 acaaacgttt tctgaatgga tatgattagc tacgatttgt atgaatcctc ttttaatagt
    15241 aggaacacga caatggaaag gagtccattc agtaatggcg tataaatatt tagtgattgt
    15301 agaatcacct gcaaaagcca agacaattga gaaatatctt ggacgaaact ataaagtaat
    15361 ggccagtgtt ggccatataa gagatttacc gaaaagtaaa atgggtatcg attttgaaaa
    15421 caattatgaa ccccattata tttctatacg cggaaaaggc gatgtcatca aaagcctgaa
    15481 agccgcagca aaaaaagctc aaaaagttta cttggcaagt gacccggata gagaaggaga
    15541 agcgattgct tggcatttag cgtacctact tgggttggat ctgaaagaaa aaaatcgggt
    15601 ggtcttcaat gaaatcacaa aagacgcagt caaagcagct tttaaggaac caagaacgat
    15661 cgatgtagat ttagtagatg cacagcaagc tcgtcgtacc ttagacagaa tcgttggtta
    15721 ttcgatcagt cctattctct ggcgtaaggt caagaaaggg ttaagtgcag gacgtgtcca
    15781 atctgtcgct ttaaaaatta ttattgaccg tgaaaaagag atccgagaat ttgttccaga
    15841 agaatattgg agcatcgacg gtaattttaa aaaagctcgc aagaaattca aagcaaattt
    15901 ctggggaatc gacggtaaga aaaagaaatt accagatgca caaagtgtaa aagaagtcac
    15961 tgctagaatt gatggaacag acttcgaagt taaaaaagta gaaaagaaag agcgcaaaag
    16021 aaaccctgcg aatcctttca ctacaagtag cctgcaacaa gaagctgccc gtaagttaaa
    16081 ctttcgaaca agaaaaacca tgatggtagc acagcaatta tatgaaggaa tcactttggg
    16141 taaacaagga acagtcggct tgattacata catgcgtact gattctaccc ggattgccga
    16201 tacagcaaaa gcagaggccg cagcatttat tgaagatacg tatggaaaag aattttctag
    16261 acatgatcac cgaaagatca aaaatgctca aggcgcacaa gatgcccatg aagctgtgcg
    16321 tccaacgagt gtgcttcgta caccagatga actcaaacaa tatttagata aagatcaatt
    16381 gaaactttat acattgatct ggtcacgttt tgtggctagt cagatgacac cagctatttt
    16441 agatacaatg aaagtgacat tagaacaaaa tggtgtcatc ttcattgcga acggttcaaa
    16501 aatcaaattc aaaggattca tgcaagtgta tgtggaaggt agagatgacg gcaaagaaga
    16561 gaaagaaaat attcttccag aacttgaaga aggcgatgta gtccaatctg ttgatattga
    16621 accaaaacaa cattttactc aaccaccagc acgttttagt gaggctacgt tgattcgtgc
    16681 actagaagaa aacggggtag ggcgaccttc cacttatgca ccaacacttg atacgatcca
    16741 aagacgctac tatgtaaaat tgacacaaaa aagatttgag ccgactgaac taggagaaat
    16801 tgtcaattca ttaatctgtg aattcttccc tcaaatcgtc gatatccatt tcacagcaga
    16861 aatggaagga gatttggata aaattgaaga aggcacggaa gcgtgggtca aagtggttga
    16921 tcgtttctat aaaccgtttg aaaaagaact gacgaatgcg gaagaaaaaa tcgaaaaaat
    16981 tcaaatcaaa gatgaaccag caggattcga ttgtgatgtc tgtggacatc cgatggtgat
    17041 aaaattaggg aaatatggga agttttatgc ttgcagtaat tttcctgatt gtcggaatac
    17101 gaaaccaatc gtaaaagaaa tcggtgtgac ttgcccagta tgtcatgaag gacaagtcat
    17161 tgaacgaaaa tctaagaaaa acagactatt ctatggttgt tcccgtttcc cagaatgtga
    17221 attcacttct tgggataaac cagtgggcag aaattgtcca aaatgtgacg gatatctggt
    17281 cgagaagaaa gtcaaaggcg gtaaacaagt agtctgtgta aatggagatt acgaagaaga
    17341 catccaaaaa taatagaaaa gaggttcttt cattgaaaat ggtaaatgtt gttggagcag
    17401 ggcttgccgg aagtgaagct gcttggcaga tcgcacaagc aggagtccct gtccgtttat
    17461 atgaaatgcg tccagtcaaa tcgactgagg cgcatcacac aagtaatttt gctgaactag
    17521 tatgttccaa ttcattaaga ggaaacagtt tggctaatgc agtagggtta ttgaaagaag
    17581 aaatgcgccg attgaattcg gtagtaatca cttcggcaga tgaaacagca gtgccagctg
    17641 gtggtgcctt agctgttgac cgcgattctt tttctgaaac aattacccga aaagtcaaag
    17701 agcatccatt agtaacagtg ataaacgaag aaattactga aataccggaa ggaatcaccg
    17761 tagtagcaac aggacctttg acttctcatc cattagcaga aagcatcaaa gcattcaatg
    17821 gttcagatgg tttttatttc tatgatgcag ctgcaccaat cgtagacaaa gctacgatcg
    17881 atatggataa agtatatttg aagtcccgct atgacaaagg agaagcagct tacttgaact
    17941 gtccgatgac agaagaggaa ttcaaagctt tccatgaggc actaatcaat gccgaagtgg
    18001 cagaacttaa atcttttgag aaagaaaaat attttgaagg atgtatgcca attgaagtaa
    18061 tggcacagcg aggattcaaa acgatgcttt tcggacctat gaaaccagtt ggattggaag
    18121 atcctaaaac tggcaaacgt ccttatgctg ttatccagct gcgtcaagac aatgctgcag
    18181 cttctttata caacatcgtg ggctttcaga ctcacttgaa atggggcgag caaaaacgtg
    18241 ttttccggat gattcctggg ttagaaaatg ctgaattcgt tcgctatggt gtgatgcacc
    18301 gaaacagctt tatgaattcg ccagaattgc tgaaaccgac ttaccaatca acgaaacgcg
    18361 aagatctgtt ctttgcaggt cagatgactg gtgtagaagg ctatgttgaa agtgcagcga
    18421 gcggactact tgctggaatc aacgccgcac gcttagcaaa agaaatggaa ccagtcgagt
    18481 ttccacaaga aacagctatt ggaagtatgg cttactacat tactcatgcg gaaggaaaac
    18541 atttccaacc gatgaatgcc aactatggtc tgtttcctga actgccagag cgcattcgag
    18601 acaaaaaagc aagatatgaa gcaattgcac aacgagcttt aaaagctaat gaggcaataa
    18661 aaacagaatt agaaaaaact gcaatcccaa atgagtaagg aaactccatg aagagggtga
    18721 gacggatagt ctcgctcttt ttcttgcgtt tttcttaaga atttctcaaa caaaatgtga
    18781 ggaattgcgc caattgtgaa caaacttaga aatattggtt aaattctgac aatttatttg
    18841 tctttttata aacgctgtgc taaattattc tctgggacaa aaggaaggtg agaaaatgac
    18901 agaagccacg tgggaacaaa aatttttgcg ttatttgatt gtcgaaagag gatattcaga
    18961 aaaaacgaaa gaagcatatg aagaagacat tctccatttc aaacattttt tggaggaatc
    19021 tggagacgct gatctgctga aggcggaata ttttacggtt cgtgtctatt tgagtgcatt
    19081 agctgatcat cgtcctagct atagcagaaa ttctatcagt cgcaagatag ccagcctacg
    19141 ttcgttttat cagtatcttc tcaaagaaga agtgataaaa gaaaatccat tttcttacgt
    19201 tcatctcaaa aagaaaaatt tgagactgcc acgttttttt tatgaaaatg aaatgcaagc
    19261 actttttgac agcgtagcag gagatagtcc tttggatttg aggaaccgcg ctttactgga
    19321 agtcctttac gggtcaggca tccgtttaag tgagtgtagc agtttgtcgg tatcagacat
    19381 tgattttgat tcagaggtca tgttgatcca tggtaaaggg aacaaagaga gatatgctcc
    19441 tctaggttct tttgctcaag atgctctgca agaatatttc agggaaggcc gccaggtatt
    19501 gatgacaaaa tatcacgaag agcatgatat cgtttttgtg aatcatcatg gaaaaccaat
    19561 cacgcctact ggaattgaat atgtcttgaa tcaaatgatc aaaaaaagca gtttggatag
    19621 tgatatccat cctcacatgc tgcgccatac atttgctact catttattaa ataatggggc
    19681 agatttgcgg acagtccaag aattgctagg acatgccaat ttatcgacta cccagatcta
    19741 tgcccatgta acaaaagaaa gtttacaaaa aaactatcgt tctttccatc caagagcgta
    19801 aaaataagga aaagaacaaa tttaggagga aacaaacatg gtcgaatcac catttcattc
    19861 aaccactatc tgtgccgtcg aaaaagacgg gaaatttgct atggctggag atggccaagt
    19921 aacaatgggt gaatctgttg tcatgaaagg cactgcaaag aaagtacgac gtatctacaa
    19981 tggagaagtt gttgtaggtt tcgccggaag tgttgcagat gcgtttactt tagaagaaaa
    20041 atttgaaggc aaactaaacg aatataacgg gaatctacaa cgcgcagctg tcgaattagc
    20101 tcaagaatgg cggacacagc aatctatgca aaaacttgaa gcgatgctga tcgtaatgaa
    20161 tgataaagaa atgcttcttg tttcaggtac aggagaagtt atcacaccag atgatggtat
    20221 cttagctatc ggatcaggag ggaattttgc gttggctgca gcccgagcaa tgaaaaacta
    20281 tgctcaaaac gacatgagtg cgaaagaaat tgcagaaaat gcgttaaata ttgccgcaga
    20341 tatctgtatc tttactaatc ataatattat cgtagaagaa ctgtaagagg tgagtagata
    20401 tgtatgaatt aaaacaaaca ccaagacaaa tcgtaagtga attagatgaa tatatcgtag
    20461 gacagcacgc agcaaaaaaa tctgttgccg ttgctttgcg taaccgctat cgccgtttgc
    20521 agttagatga aaaaatgcaa caagatatta caccaaaaaa tatgctgatg atcggaccta
    20581 caggggtcgg taaaacagaa atcgcacgac gtttggcaaa aatcgtcaat gcaccatttg
    20641 tcaaagtcga agcaacaaaa tttactgaag tcggttatgt cggaagagat gtagaatcaa
    20701 tggttcggga tttagtagaa aatgcgatcc aaatcgtaga aaaagagcag tacagccgtg
    20761 tatacacaag tgctaaaaaa aatgcagaaa aacgtttggt aaaaatcttg gtacctggta
    20821 tcaaaaaaga acagaaacaa tccactaatc aatttgaaca aatgatgaat ctttttaatg
    20881 ctagtcagca aaataccgct gaaccgcaag aagaagtgac agaagatatt cgaatcaatc
    20941 gccgtacagt cttggaacaa ctacaaaagg gtttactgga tagtcgtgaa gtaaccattg
    21001 aagttgaaga ccaaaagaaa cctgcaccaa tgatgaacaa tggattggag caaatgggga
    21061 tcgacctaaa tgaaactcta ggtgctttga caccgaagaa aaaagtggaa cggacggtaa
    21121 cagtcaaaga agctttagag ttattgatca aggaagaatc agcaaaatta gtcaaggatg
    21181 ctgatatcca tagtgaggca atcaaattag cggaagaaag tggaattatt tttatcgatg
    21241 aaatcgataa gatcacttct aaatcacagc aatctggaga agtatccaga gaaggcgtcc
    21301 aaagagacat attgccaatt gtcgaaggtt cacaagtaaa cacaaaatac gggatcatcc
    21361 aaacagatca cgtcctattc attgcttcag gagctttcca tttgtctaaa ccaagtgatc
    21421 taattccaga acttcaagga cgcttcccga tacgggtaga attagatgat ttgacagctg
    21481 aagattttgt gaagattctg accgaaccaa ataatgcttt agtaaaacaa tacgtcgcgt
    21541 tgatcggtac agaaaatgtg tcagttacgt ttacaaaaga agcaattgaa cggatcgctc
    21601 aaatcgcttt cgatgtcaac cgtgacacag ataatatcgg cgcacgcaga ctgcatacca
    21661 ttttggaaaa actactagaa gatctattat ttgaagcacc agatatgcaa atgggagaaa
    21721 taacgatcac agaagcatat gtggatgaca aacttggctc aattgcggca aatgaagatt
    21781 taagtcgcta tattttataa aaaatcggag gacgacaatg acagacttgc taacgaaaac
    21841 ccgcaagata aacacacttt tgcagcaaaa gaatactttt gacatgcaag cagatttgcc
    21901 ttacgataaa atggctgtca cactaggtgg tattcttgac agcaacacct atatcatagg
    21961 aagtgacgga gtattactag gttataatga acgtcacgat gtgaacaatg aacgaatcaa
    22021 aacaatgttt gttgagaaac aatttcctga atcttatact gatacagtgg cacagttgat
    22081 gaaaactgaa gctaatatcc caattactag tgatattact gcatttccgg tagagtcaag
    22141 agagaaatat ccatttggtc tgacgactgt cgttccgatc tttggagctg gcgaacgttt
    22201 gggtacgatt atcttatctc gtatggaaca atcgtttgca gatgacgatc tagtcttagc
    22261 agaatatgga gctacggttg tcggtatgca gatcctttat cagaagtctc gaagcatcga
    22321 agcagatgta cggagtgcaa cggctgtcca aatggcaatc aacacattat cttatagcga
    22381 attgaaggct gtacaagcta tctttgaagc attggatgga gatgaaggtc gtctgactgc
    22441 ttctaatatt gccgatagta tcggcatcac tcgttctgtg atcgtcaatg ctttacgaaa
    22501 attggaatca gctggaatca ttgaatctcg ttcgttaggc atgaagggaa cttatttaaa
    22561 agtattgaat tcccgtttta aagacgagtt agcaaaacac agttattaga agtaagggga
    22621 ctggggcaga tagaaatgtt tgttccagcc ttcccatttt aaaaagtaag tcgaagttgg
    22681 aggaatggca atgactgtta ttattcaaaa tgaccagctg atcgccgaaa tcgctgaaca
    22741 cggtgcggaa ttgatcagtc tgaaatcaaa agaacatggt ttagagtata tctggcaagg
    22801 tgatccagcg tattggggca gacatgcacc ggttttattc ccttttgttg gacgtttaaa
    22861 agatgatcag tatgtttatc aagggaaaac atatcaaatg gggcaacacg gatttgctcg
    22921 ggatatggat tttgaagtca ttgaacatgg acaagaaatg gctagtttca tcttaaggag
    22981 tacgccggag acattagaaa agtatccatt tgattttgaa ttagtgatca gctatgaatt
    23041 aggaggagac ggcatcacgg ttcattatca agtggcaaat accggtgaaa aagaaatgtt
    23101 cttttctatc ggtggacatc ctgctttcaa tgtacctctt gaagaaggat tgtcatttga
    23161 agatttctat ctggcatttt ctccattgaa atcaagatta cgcctaccat tgaaaggccc
    23221 attcatcgat atggatcaaa agacgttagg tcagacaaat acgaatctgg ctttgaatcg
    23281 tgaacttttt gagcaagatg ccttggtttt tgaaacaagg ggtctaaatg cgtacgccat
    23341 tcgaagtgaa aaatcttccc atagcgtaac tttaagctat aaagatatgc cttatgtagg
    23401 gatctggtct ccttatccaa aagaagcgcc tttcgtttgt atcgaaccgt ggtgcggaat
    23461 cgctgacacg gtgaacagta gtggaaactt gatggaaaaa gtagggatca atcaactagg
    23521 tgcccatgaa atcttcaaga caaaatattc catcacagtg aagtaagagg ttgtgaccga
    23581 gaagttagca gggaacaccg tttaccaagg tgtgtaaaaa agctatcctg taagtaataa
    23641 gggagtgtga catcgatttg tcacactccc gttttatctc tttggaatga aaaagtatca
    23701 ggattttttc ttgctgctat tcaaaccaaa cgggattcga ctttcagtat ggtttctgat
    23761 acgcttgata ttgtctttat gccgataaaa gataaaggaa gaaactaaaa aggcaatgat
    23821 cgtcagtaac caattgggct tagccaaaat cacaggagct acataaggaa ggacgatcgt
    23881 agataaagtg atcaatactg cactgatcat actgctcaaa ctcaccatac ttgtacaaaa
    23941 taaactaacg ataaagatga tacaagaata aacaaaaaat acaggattaa atcctaaaag
    24001 cattcctgca cttgtcgcaa cagcttttcc tcctttgaac ccagcaaaaa tcggaaatgt
    24061 atggccaaga atggcgcata ccccaaacca aagagggtta atcccagaaa ggtggaagat
    24121 catcggcaaa caagtagcca atgtaccttt taaaatatcc ataagcagga caacaatccc
    24181 ggctgttttg cctaatacac gaaatgtatt ggtcgttcca gtattaccgc tcccgtgttg
    24241 tcggatatct tttttgaaaa acaatttgcc aatccagaca ccggaaggaa tagaacctaa
    24301 aagatatgct aaaataagta ataagatcaa tttcattttt taccctcttt caagttgaaa
    24361 actatccttt attttagcat gaataggtaa caggaacaat tgaaaaaatg aaagatacaa
    24421 gtataataga tggaataaaa agaaaagcaa ggggtggcag aaatgtctgt aaaaaatcca
    24481 acacaagaaa cgattttcaa ctatttggaa gaagcaaaaa atattgccgt cgtaggcttg
    24541 agcaataaac cagaacgaac aagttacatg gttgcacagg tattgcaaga caatggatat
    24601 aaaatcatac cagtaaatcc attattggct ggtgaagaaa ttctaggcga gaaagtctat
    24661 gcgaatttga cagaaatcga tgatccaatc gatatcgtag atgtatttag acggagtgaa
    24721 tttttacctg aaatagcagg tgattttttg aaaactgatg ctaaagtgtt ctgggcacaa
    24781 ttagggattg aaaacaaaga agcagctgag atgctaagaa aagcaggacg tacagatatc
    24841 gtaatggatc gttgtattaa gattgaactt ggtaagttga aagaaaacca aaaataaaaa
    24901 tgaccacaaa gaagagatga tcgatagagg ggaatgtcga aaaagcggtt aggagataat
    24961 taaaattgat ttctcgtcta ccctcttttt tttcacgacc ttttctagta tgataatcgt
    25021 ggtgcggttt tgccgcaaag tattattgaa ggagcgtttg ccttggcaaa aaaagtaaac
    25081 aacgaataca atgactcgtc catccaagta ttggaaggat tagaggcagt tagaaaaaga
    25141 ccagggatgt acattggatc cactgacagc cgaggcttgc atcatttagt ctatgaaatc
    25201 gtcgataatg cagttgacga agcattatca ggttatggca gtgagattga tgtgaccatc
    25261 catgaagaca atagtataac tgttgcagat agcggacgtg ggatgcctgt aggaatgcat
    25321 gcttccggaa taccaacagt tgaagtgatt tttactgtgc tgcatgctgg cggaaagttt
    25381 ggtcaaggag ggtacaaaac ttctggtgga ctgcacggtg taggagccag tgtggtaaat
    25441 gccttatcga aatggctaat tgtaacgatc gttagagatg gcgtagagta tcagcagaaa
    25501 tttaaaaacg gcggtaaacc tgacggtact ttgaaaaaga taggaaaaac aaaaaaagca
    25561 aacgggacga ctgtccattt tttaccagat gatacaatat tcagtacaac gaaattttca
    25621 tatgaaattt tagccgaacg gttaagagaa tctgcctttc ttctaaaagg cgttaaaatc
    25681 tctctttctg atcttcgtgg agaagaacca gtcaaggaaa tttttcatta cgaagaagga
    25741 atcaaagaat ttgttgatta tctgaatgaa gaaaaagata cattgacacc agttgtttat
    25801 ttttcaggag aaaaagaagg tatcgaagta gaggtcgctt atcaatacaa tgacggttat
    25861 tcagaaaatg ttttatcttt tgtcaataac gttcggacaa aagatggggg aacccatgaa
    25921 gctggtatga aagcggcgat gacgaaatct tataatgaat atgcgagaaa agttggtttg
    25981 ctgaaagaac gggacaagaa tctggaaggt agtgatttca gagaagggtt agctgctgta
    26041 ctttctatcc gtgtacctga aaatcttctg caatttgaag ggcaaacaaa agaaaaactt
    26101 ggtacgccag ttgctcgtac cgtagtagat aacgtcatca gtgaacaaat gggcttttat
    26161 ttgcaggaaa atagcgaaat gagccagatg ttggtccgta aagcaatcaa agccagagaa
    26221 gcgagagaag cagcacgtaa agccagagaa gaaagccgaa atgggaagaa gcgtaaaaaa
    26281 ggcgaatctc ttctttcagg aaaattgaca cccgcacaat cccgaaaccc taagaaaaat
    26341 gaattgtatt tagtcgaagg ggattctgct ggcggatctg ctaaacaagg aagagacaga
    26401 aagttccaag caattctacc tttacgagga aaagtcatca ataccgaaaa agctaaaatg
    26461 caagatatct tgaaaaatga agaaatcaat acgatgatct atacgattgg tgcaggagtc
    26521 ggtcctgagt tttctatcga agactgtaat tacgacaaag taatcatcat gaccgatgcg
    26581 gatacagacg gcgcccatat tcaagtatta ctgcttactt tcttttatcg ttatatgaaa
    26641 ccgctgattg aagctgggaa agtatatatc gcgttaccgc ctttatataa agtatccaaa
    26701 ggacaaggaa agaagcaagt cattgaatat gcgtggacag atgacgaatt ggcagcaatg
    26761 attaaaaaag tcggcaaagg atatatgctg cagcgatata aaggacttgg agagatgaat
    26821 gcggaacaat tgtgggaaac aacgatggat ccgacttccc gtacgttgat ccgcgtccgt
    26881 atcgatgatg ctgcgcaagc tgaacgtcga gtaaccacac tgatgggtga caaagtagaa
    26941 cctcgaagaa aatggatcga aaatcacgtg caatttacgc tcgaagaaga tggcagtatc
    27001 ttagataaaa aagaggatac tgaaatctct ccttcagttt ctaatgattt attagatgaa
    27061 gaacgagcag ataaaaatga aaacaatcag ttatttgaag tagaatagga ggtcacctga
    27121 tggaaaatcg acaagaagta caagaattaa ctttagaaga agtgatgggt gaccgcttcg
    27181 gacgttattc caaatatatt atccaagaac gtgcactgcc tgatatccgt gatggattga
    27241 agccagtgca acgccggata ttatttgcca tgaacaaaga tggcaatacg tatgacaaag
    27301 gattccgtaa atcagcaaaa tctgtcggaa atatcatggg gaattatcac cctcatggtg
    27361 accgcagtat ttatgaagcg atggtccgca tgagccaaga ctggaagttg cgggaagtac
    27421 tgatcgaaat gcacgggaat aacgggagta tggacggtga tccacctgct gcgatgcgtt
    27481 atactgaagc cagattatcc aagttaagtg gagagatgct agcagatatc gagaaagaaa
    27541 cagtcgatct cgtgtggaat tttgatgata cagaaaaaga accaacagtc cttccagctc
    27601 gatacccaaa ccttctcgtc aatggatcga caggtatatc tgctggatat gcaacagaaa
    27661 tcccgactca taacttagct gaagtgatcg atggcacaat ctatatgatc gatcatccac
    27721 aagcgagcct tgaaaaattg atggaatata ttcctggacc tgactttcca acaggaggga
    27781 tcttgcaagg aaaagatgaa atcaaaaaag cttatgaaac aggacgagga aaagttattc
    27841 ttcgttcgaa aacaaagata gaggcaatga agggtaataa acagcaaatc gtgatcacag
    27901 aaatcccata tgaagtaaat aaagcgacct tggtgaaaaa aatggatgag atccgtttga
    27961 ataagaaaat cgatggaata gctgaagtac gagatgaaag tgatagaaca ggtctgcaaa
    28021 ttgtcgtcga attgaaaaaa gacgccaatg ctcaaggaat tttgaattat ttgttcaaaa
    28081 acactgagct acagatcaat tacaatttca atatggtcgc tatcgaccat atgactccgc
    28141 atcaagttgg actgaaagac attttaagaa gttatatcga gcatcgaaag caagtcataa
    28201 caaaacgtag tcaattcgat ttagccaaag ctcaaaaaag acagcatatc gtagaaggat
    28261 tgatgaaagc tttatcgatt ctggatgaag taatcgcaac gattcgtgaa agtaaagaca
    28321 aaaaagacgc caaaaagaat ttagtcgacg tctttcaatt tacagaagaa caagcagaag
    28381 caattgtcac attgcaatta taccgtttga cgaacacgga tatcacagag cttcaaaagg
    28441 aatccgaaag cttgattgcg caaatcacag agttgaataa aatcctttca aatgacaaag
    28501 agcttttctc tgttatgaaa aaagaattgc gagaagtgaa aaaaaattat tcttccgctc
    28561 gtctaacgac aatcgaagac gaaatcgaag aaatcaaaat tgatacgcaa gtcttagtgg
    28621 cacaagaaga cgtaattgtc agtgtgacgc gagaaggcta tgtgaagcga acaagccttc
    28681 gttcttatag tgcttccaaa ccagaagaaa tcgggatgcg agaaggcgac tacttgctat
    28741 actcaggtga attgagtaca ttggaccatg ttcttctgat cacaaataaa gcaaatgtga
    28801 tctaccgccc tgtccatgaa ctacccgatt tgaaatggaa agatgctggt gagcacattt
    28861 ctcaaacaat ctccaatctg tctgtagacg aatcgatttt agctgttttc ccatatcaaa
    28921 aaattcaagc agagaaaaca tttgtattca tcagcaagaa tggattgatc aagcaaacac
    28981 gaatgacaga gttcgaacca tggcgcacct ataagagccg tccgctcagc tgtatgaagc
    29041 taaaggcgga agaagatgaa ctgattgctg tgtatctgaa agaagatcag ccaggcttag
    29101 atgttttctt agtaacgcat caaggaatgg gtttgcgcta tcctttaaca gatgttcccg
    29161 ttgttggagc aaaggcagct ggagtgaagt ctatgaattt gaaagatgga gataggatta
    29221 tcaacgggct gcttgtgtta gcagaaggtg atacgccgat cgtaatcgtt actcagcgag
    29281 gagctgttaa acgcatgctt gctcaagaaa tcagccaaac ttcacgtgcg aagcggggag
    29341 tgacggtcat gcgtgagctg aaaaaaaatc cgcaccgtat tatctatatg tcggaaggaa
    29401 gatcaaaaga aataaccttg atgaatcaaa aagggcagca gttaacgatt gacccaactg
    29461 atttccctat aggtgatcga acatcgaatg gatcatttgc gatggatgag aaaaaaggtg
    29521 gagaagtcat cgaagttatc gatgctcctg agattttcat cgagtcgtaa ctgttgtagt
    29581 attttaatga agagacgcca tctgtattaa tacaggtggc gtctcttttt cattcatttt
    29641 taataaatcc ttatacgttt gcaaaaaaag atgaaagtgt tcacaatgct taaatgttgg
    29701 tatgtcaacg ttgatttaaa tatatgtaaa taaaacataa aaattgttaa ataaaaaaca
    29761 agaaaaccct tgcaaagata gggtgctgtg ttatactaat cacgtaaaaa ctgttacata
    29821 aaacagaaat ttaggaggtc catacaatgg agcaatggaa tggatttaaa ggtaccaaat
    29881 ggaaagaagg cgtagacact agagacttta ttcaaaataa ctacactgaa tatcgcggtg
    29941 atgacagctt tttggaaggc ccaacagaag caacagaaaa attatgggat gaattgcaaa
    30001 agttaaatga tatccaattc gagcgtaacg gtgtctatga tatggacaca gaaatcgtat
    30061 caactattac ttcacacgat gcaggctatt tggataaaga tttggaaaaa atcgtcggtc
    30121 tacagacaga caaacctttg aaacaagcat tcatgccgtt cggcggaatc aatatggcta
    30181 acaatgcgct aaaaagcaat ggctatacac caaacgatga attgacacat attttcactg
    30241 actggcgcaa aacacataat caaggtgtat ttgacgctta tactgctgaa atgcgtgctg
    30301 ctcgtaaaaa caaaatcatt acagggcttc cagacgctta cggtcgcgga cgtatcatcg
    30361 gtgactatcg tcgtgtggca ttgtatggaa tcgactattt gatggaacaa aagaaaaaag
    30421 atcatgatat gactggttat catacaatga gtgaagaagt gattcgttta cgtgaagaaa
    30481 tcactgaaca atatcgtgca ttagcgcaaa tgaaagaaat ggctgcgaaa tatggctatg
    30541 atatttctaa accagctgca aatgcaaaag aagctgtcca atggctatac ttcggatatt
    30601 tagcagcaat caaatcacaa aatggtgctg cgatgtcaat cggacgtatc tcagcattcc
    30661 ttgatatcta tatccaacgt gatttggata atggagtaat cacagaaaaa gaagcacaag
    30721 aattgatcga ccacttagta atgaaattac gtatggtcaa attcgcgcgt acacctgaat
    30781 ataaccaatt attctcagga ttccctatct gggctacttt atccattgca ggtatgggat
    30841 tagatggtcg ttcattagtt acaaagaatg atttccgtct gcttcataca ttaacaaata
    30901 tgggaccttc accagaacca aacttgactg ttttgtattc tgaacacctt ccagaaggat
    30961 tcagaacata tgctagcaga atcgctatcg aaagttcttc gattcaattc gaaaatgata
    31021 atcagcttcg tgaacaatgg ggttctgatg attgtgcgat tgcttgctgt gtatcaggaa
    31081 cagttgtcgg aaaagacatg caattctttg gcgctcgtgc taacttggct aaaacactat
    31141 tatatgccat caatggcgga gtcgatgaag tgactggcgc ccaagttgga ccagaatatc
    31201 gtccaatcac atcagaaata ctagactttg aagaagtgaa acataacttc atgaatatga
    31261 tggattggtt agcagaacta tatgtcaata cgttgaacat cattcattat atgcatgata
    31321 aatattctta tgaagcagct cagctggctt tgatggattc tgacttgcaa cgcacatttg
    31381 ctacaggtat tgctgggatc tctcatgcgg cagacagctt gtcagcgatc aaatatgcaa
    31441 aagtaaaagc aatccgtaat gaaaaaggaa tagcagttga ttttgaagtg gatggcgact
    31501 tccctaaata cggaaatgat gatgaccgtg cagatgaatt agtttcatgg atcttggaat
    31561 acttcatggg acaaatcaaa cgtcataaaa cttaccgcaa ctcaaaacca acaacttcat
    31621 tattgacgat tacttcaaat gttgtttacg gtaaaaatac aggaaatact cctgatggcc
    31681 gtgaagctgg aaaaccactt gcgccaggag caaatccaag ttacaatgcg gaacaaagtg
    31741 ggttattagc tagcctgaac tcaacagcta aaatgaatta cggctgtgca ttggatggaa
    31801 tttcaaatac ccaaacaatc aatccttcag gtcttggaaa agaacaagat acaagaatcg
    31861 aaaacttgcg taatgtctta gatggatact tctcaaaagg agcttatcat ttgaatgtca
    31921 atgtattcag taatgattta ttgcgtgatg caatggaaaa tccaatgaaa tatccgaact
    31981 tgacgatccg ggtatctggt tatgcagtta aattccgtga cttgacaaga gaacaacaat
    32041 tagatgtctt gatgagaact tcacacgaca gaatgtaaaa agttcgtgaa aaaagttttt
    32101 cgacttagcg tcgaaaggac gttgaatagc catcgcatca aaatcgaata atcagtatgc
    32161 ttatttgaaa gaaacgattt acaggggcag gacttgtatg ttccgtccct gtaaatttta
    32221 cacataacga agcggcaatt gcgaaaaatt ttgttcagaa agcttcgctt cgacagctaa
    32281 cttgtactta aaatgaaatc aaagaaaaga tgtgaactta aatggaagaa aaaacaatcg
    32341 gctatgttca ttctatcgaa actttcggtt cagtagacgg acctggactg cgctttgtcg
    32401 tgtttatgca aggatgccgc atgcgttgcc aattttgtca caatccagat acttggaata
    32461 ttggcggagg gaaagaatac acagcagatg aacttttaga taaagcagaa cgcttcagac
    32521 cttactgggg agataaaggt ggtattactg ttagtggtgg agaacctcta ttgcagatcg
    32581 attttttgat cgaactattt aaaaaagcaa aagagcggaa gatgcatact acattggata
    32641 catgcggaaa accttttacg tatgaagaac ctttcttttc acgttttcaa gaattgatga
    32701 agtatacaga tttactgtta tttgacatca aacacatcga taatgaagag cataaaaaac
    32761 taacgcattg ggacaatgaa aatattttag aaatggctca atatttgtca aaaatcaaca
    32821 aaccggtttg gattcgccat gtactagttc ctgagcgaag tgattatgat gaatatttga
    32881 tccgactaga caactttatt caaaccttgt caaatgtaga cagagtagag attcttcctt
    32941 atcatacgat gggaaaatac aagtgggaaa cacttggttt gaaatatcca ttagaaggga
    33001 tcgaaccacc tacaaaagaa cgtgtcgaaa atgctaaacg attgcttcat acagaagagt
    33061 atacaaaata tttaacgcga taggtcgcat cggaaagaag ataagtattg cttctttccg
    33121 tttttttgct attattaaat aggagaaatc acaaaggagc gaatgacatg tcaaaaattt
    33181 tagtttttgg tcaccaaaat ccagatacag atgcaatcgg ggcagccatt gcgttttcac
    33241 acttgcaaaa tgaattaggt aaagaaacag aagcagttgc tctaggtaca cctaatgaag
    33301 aaacacaata cgcattagac cactttcagc tatctgcacc acgagtagta gagtcagcta
    33361 aagcagaaaa tgcagatgtc atgcttgtgg atcataatga attccaacaa agtatttcag
    33421 atatcagcga agtaaatatt ttagctgtag tagaccacca tcgtattgca aactttgaaa
    33481 cagctaatcc attgtactat cgtgcagaac cagttggatg tacaagtacg attattttaa
    33541 aactatataa agaaaaccaa gtaacaattc ctaaagaaat cgcaggaatc atgctctcag
    33601 ctatcatttc agatacattg ttgttcaaat caccaacatg tacgcctgaa gatgaagcag
    33661 ctgcaaaaga acttgcagca atcgctgaag tcgatctaaa cacttatgga cttgaaatgt
    33721 tgaaagcagg aacaaatcta agtgataaat cagctgcggt tcttcttgat ttggatgcaa
    33781 aaagtttccc aatgggcagt tccaacgttc gtatcgctca agtcaataca gtggacctta
    33841 atgaagtgat ggatcgacaa gcagagctag aagcagcaat ggaagatgaa atgaaagcaa
    33901 atggctacga tctgttcgta ttagttgtca caaacatctt agacagtgat tcagaattac
    33961 ttgttgctgg taaaggaaaa gaaaaagtag aagaagcttt ccaaacaact ttgaccaaca
    34021 accgtgcttt gcttaaaggt gtcgtttcac gtaaaaaaca agtcgtacct caattgacgg
    34081 ctgtatttag ctaatcaaat ggtagtatga agcattcaaa atgaatggat aagcgattga
    34141 tataaaaaga aacatagaac atactaaagg ccgaagaaat ggaggagaat aacagtcaat
    34201 tatgactctt gttcttcctc ctttttacgt aaaagccttt taagtaaaat aaaacggata
    34261 gaaaagagaa catatatgaa ctattattca aaaaataagg aaaactttta tcaaaaactg
    34321 accgatgatc cgcttttttc ttcattgacc gattatctat atgaacatcg agaacaagaa
    34381 acgattctaa gagaattgaa aaaagaattt tcgcaaaata aattttccca ttttcttgat
    34441 ttattgatcg atgcaggatt aatcaagagg gaagaacgaa gatatcattt gaactttcca
    34501 atatttgatc ctaaagatta cttgcaacaa gccacttcgg ctgctgaaac catagctgaa
    34561 caattgaaga gactctctgt tgatgaacaa aaattagcga tgggagaagt tatttgggcg
    34621 tattgtttcg aagatgaacg gaaagaagcg tatttttatg gagtaagaaa cagccgagag
    34681 acagaattgc tgaggacaac tgcaggaaat gagaagtacc gttttatcac actttcctct
    34741 atagaacact tcccgcttac tttggctaat tacttttttg tacagaagaa tcagcttcct
    34801 gtaacgaagg cattcaaaga attagccgaa cttattggag acgtaaatga atcgtacttt
    34861 tttgatcaaa tagaagttat cgttgacagg atacgtaaga ataaatataa aaatcgccgg
    34921 cctagtattt tccatcagtc tctacttgtg acgaatacta taaaggaaga agaatcattc
    34981 acattagaat tacctattgt cgaaaaaaac aattttgaga ttgaattacc aacattggat
    35041 ccttcattga caatggagga aatggccttt cttaaacgac aaatcttttc tgagctgagc
    35101 aagaaattta taccgcatgc attttcttat atcaaagaat atggaacagt tttagtgagt
    35161 aaaacctaag agagcagtaa gcaaaaatta tactgactct tgcaggagga gcctttctct
    35221 tcctttatgg ttaaaagaat tatttgagta ttttgcctat ctaccaccta ttagattcac
    35281 tacatggtct ggaaacaaag gaatgcaaaa aaatggtgag aaatgtggaa tgacaaagga
    35341 agtagtgata agaaaagtta gatttttaaa taatcaatat tatgattcag tcaagtatgg
    35401 cattttatgg gaagaactag ctgattagat taggaagtcc atttgataat ccagaatcac
    35461 taagaaacga atggcgagtc attaataatt tatccaatct tgggttattc ttttagattg
    35521 aagtgtttaa aactaaaaaa gcatttatga agtcgtaata gtcaggcttc aaaatgcttt
    35581 ttattttgtt tgttttttct ttgccacata aatacaccta gactgacgat gaagagcata
    35641 tccaacagat ttcctgcgac ttggatcgtc gaagggttgg tcagtggcat taaagcaagg
    35701 acaaaaaagg aaaacaagct gtaaataaaa caggtgacag gaactaatcg aaagaagagc
    35761 ggacatttca attggctaaa aatgagtgaa aaaataaaat aagtaaaaat ggataaaatc
    35821 acgactaaac cattcatgat aaagaagaaa agcgtattgt gattaaacga ataaaaaaga
    35881 attgctaaaa aagaaaacgt tttaaatgca atcaatacgc ttgaagcttc gtttaacgta
    35941 ccaggatgtc gatgaaaaaa ataggcaccg aaataaacag aaaacagtaa gccgcaaaga
    36001 gaagacaaaa tcaaaaaaaa cggattttct tcggcttctg tgatatcaga atgatccaaa
    36061 agcaaccagc ctaatgcact agaaggcgca tgtgaggtct taaggtatga ataacataga
    36121 aaaaataaga tcgtcaaagt tgcaaaaaaa gagcctaaat gtaaaaaatt agtggttcta
    36181 cgttgaattt ccataatatc tccaaattaa attgataagt atataaagta taataacaaa
    36241 ttgatgagta tatgtcgatg ttttttaatc aaaataataa ataaaaactg tctaacattt
    36301 aaaatttaat ttagatatta gacagttttt aagtttgtga gttattttcc ttgtcgtttt
    36361 ctcacttttt tagtccagaa accacctgaa atatattttg gctcataaga aatgataaaa
    36421 gcacgctctt cgatttcttt gatcaggcga tacagttcac gttcgctttt tctaggagaa
    36481 agtatttcga gaactagccg ctcaccttcc agccccattg cagaagtctg tgtcacacca
    36541 taaccgtgtt ctctcagtat acccggcaaa cttttatctt ctgcgctatt tgctggcaaa
    36601 atcgttgtga ccatgatgta tcctaatgcc aatttgtctt caatcaaaat tccgacactg
    36661 atacctactg cgtaacctaa cgcatagaca aataaattca gtggattatc taaacgatct
    36721 aaaacaaggg ataagccgac gatataaatc gtgatctcga ccatactgac aagtggagca
    36781 atcagtcgat agcctttcat tgtcaacatg aaacgtaacg tgttcagagt gatataagca
    36841 aaattaatga ggaagatcat ccccaacatt tttggatcaa tcatttgtaa aactcctttc
    36901 atttatataa caacaatatc aaaaaaaatc gtaagtgaag aaaaattgaa actttataca
    36961 tacaaaaaaa tgataaaatg attataatag aattataaag ataggttagg tgattaaaat
    37021 gaaaacggtc aatcgtgtgt tttgtgccag ccacgtgcta agtctccttc tcagtatata
    37081 cttaggtgtc tattcgattc aacagccaat tgaggtagag aacattgttt ttcagatgtc
    37141 gctgacagat ggtttaattt taagcgtttt tttctttttg atactgttta ttggtaatat
    37201 tttcggtagc gttgccagtt ttttgaattt ttctatttat ccactccttt cgctagcatt
    37261 aggagtggtg ggactttgtt ctctgtgctt atttcccgag ccattcagtc ctgcatttat
    37321 attatttggt acactgaacc tgttccagac aactgttgga gcatggttgc tatggcgatc
    37381 aggaaattta atgaaaatag gtgagtaaca attgaatcca attatattga aacgttctgt
    37441 ccatcatatt ccagtgttag aagttgttct gaaagaatta agagaggaac gtattcccgt
    37501 tgtcatctat tatcacggat ggcagacaag taaggagtta gttttgacgc aaggaagaaa
    37561 aattgcgcag cagggcattc gtgtgatcct gccagatgcg atgaatcatg gggagcgcaa
    37621 acagccggtt tcttctattc catcctatac attttgggat agtatctacg gaaatctgtt
    37681 tgaatttgac acacttatca agcatttaga aaaaagaggt cttctacatg atcagcttgc
    37741 agttggcggg gtttcgatgg ggggaatgac aacatgcgcc ttgttggcta aacatcctca
    37801 tatagtagcg ggcgtgtgtt tgatgggttc ccctgcacct ttggaatatg gaaaagaaat
    37861 cgtaaggcgc gcatcggaat ataattatgt cgtaccaaaa gactattttg atttgatttc
    37921 atgggttaag agctatgatt tgtcattgca gccggaaaag ttagctggac gtcctctgtt
    37981 cttttggcat ggacaagctg acgaaaaaat cccttatata caaacggaac gatttgtaga
    38041 aaaaaatcgg cataagtctt acggaaaaga aattgttttt cgttcctcaa aaacacagcg
    38101 acatatggta caaataccac taatggaaga agcttccact tttttagcaa aaaatttgat
    38161 aaaaaagtat aaataattga aacggaaaat cactcatgac gatagaggat tttccgtttt
    38221 ttattttggg ctataataaa ctctgttagg aaaatttggt ataattgata gtaagaatga
    38281 caacatgtta gaaaggaaga gagcatgccc actttagcag atgttgcaaa acgtgccaat
    38341 gtttcaaaaa tgacggtctc tcgagtcatc aatcatccgg aacaggtgac tgacgaattg
    38401 aaagagttag ttttctcagc aatggctgaa ctggattacc gtccaaatat tgctgcaaaa
    38461 gcacttgtca cgaatcggtc gcagatcatc aaattattta tactggaaga aatcgacaca
    38521 actgagccct attacatgaa tttgctgatg ggaatcgcta aacggatcgg taaagcgcat
    38581 tattctctcc aattagttac aaatgatgcc ttcgacgtcg gttcttgtga tggatacatc
    38641 atcacaggtg tcagaaaaaa agacttcgat tggatcgacc gtttggaaaa accagttgtc
    38701 ttgtttgggg aaaattctga aggatatgat tatgtagaca gcgataatga atatggtaca
    38761 gcaaaagcaa cgcaatatgc cttagaaaga gattatcaaa cgattattta tatcggtatc
    38821 gaagtggacg agccttttga aatttcaagg gaaactggtt atttatctgt gatgaaggaa
    38881 gttgatcttc ctagtaaaat cttgcggttt ccaaatcatt cgacagaagt agaaagatat
    38941 atgacagaaa actgggcaga ttttacagat aaaacttgtt ttgtatgtag ttcagatcgg
    39001 ctagcactag gagcagtaag agggattata aatgctggag gacacttgcc cgaagaattt
    39061 ggtgtgattg gatttgatgg ggtattttta gaccaaatca gttcacctaa attgacaacg
    39121 atcaagcaag atattatacg tatgggtgaa gtatgtggag aaatgttgtt aaaaaaaata
    39181 gaagaaaaag gggcgagtca aggttatcgt cgtttttttc ctgaactagt tatcagagag
    39241 acaacgaatt aagtcttatt actatatata tatttatgaa attcatcgct attttcttaa
    39301 aataatcagc gcattgctac tgaaaacaat gaatctgtgc tattattgag aaaagttcca
    39361 tttttgagaa ggatggtttg aatgaaagaa atcagacgaa aacatttccg ttttcctgcg
    39421 tacgatgatg agttaggcgt aaaattaacc aacgacaaga agcgagtatt atttgacgga
    39481 caagaagatc ttttgactga acagaatcag tccccgtttg aacagatgaa agaatttcat
    39541 ttcacgaaca cgaacaccga gaaaatccgt cgcaagcgtc gtgcaacaaa tggattgaag
    39601 tcagctccgc gtaaggaaaa tttggaaaag cataaaggaa aattaccgga ttataccggc
    39661 cattaccaat cagaaatcac atcgacagga cgaaaaaaac tttttggtga ttcctctcgt
    39721 tctgtcagac aaagtgaaac aaggacagag tccaagcata ctacacgaaa cgcatctgtt
    39781 gacacgaagg tgcgggagcg ttcttatttt gttcctaaat atgtacccgc atcgattatc
    39841 ccagacccta gagaaagcaa aatttctgag gatcatttaa tcgaatcgat gaaaaaaacg
    39901 gatgactctt atctgttgtt cgatacagaa ccgacgccgt atcaagaaaa aagaaatggt
    39961 gagccgtctg tacgaacatt caatcgaaca aaaacgttag aggaaacaaa gcagtcagaa
    40021 gaaaaaaaat cgaaaaaaag ccatggtatc ttagaacgct cattacaagg attgatcgat
    40081 gatcaaggaa actctttggg agaaaatagc tattttaaat aagtgatata caaatttata
    40141 ttcggctaca gttggaaagg aaacgctgcg gcgtttcctt attttatact ctatccgaaa
    40201 gtttatatcg tatcctcaaa tttttttgag tttaagcgaa ttttttctcc caataagtaa
    40261 gaaaataatg gcaaaataaa aaaacaaact attttcgcag atcgtttgca aaaatagttt
    40321 atttttttat aaagaagatt ttactgaata atatcatttt agtttacata atgatatttc
    40381 tgtaaattaa ataaagtagt gaaaaataag aatcagtgct ctaactgttc aagaggatca
    40441 agtggttcaa atgtttctgt agtctgtttt gcttccaatt ggggcaaaac agatccaatt
    40501 tccagatact tcactttatt caatgtataa gatagaatag aacagctaag taatgtatac
    40561 agaaaatgtg tgagatccaa ataaagcaag gagacaacta aaataccaaa agtaatcaag
    40621 aaaagacttt tgccaatctt aatatgaaaa tatttttcaa tggcttgata aatgatatct
    40681 gttccgcctg tgcttccgcc gaatcgaaag acgagaccgc aaccaatgcc agaaagaata
    40741 cctgtcatca aactattgat cagtagacta tctacagcaa aatgtatatg aaggctctcc
    40801 cataaatgta aaaagaaaac tagcgcaaat gttccgacga tcgtccggag aaaagcgtgt
    40861 tttccaaaaa gaaacaatga gataagcaat aaaggtaaat taaaaagcag tgaagtgaca
    40921 gaaggagcga atccaaaaag attatgcaaa agcaaagcaa taccagtaac cccaccatct
    40981 gccagcttag atggaatatt gattcctgtc acagctaatc cgtagattcc tgcgcctaaa
    41041 atgattccgc acaattctgt aaataaattt aattttttca tttctagcct cttttctttt
    41101 gaaaattttc agcaacttct ttattatact gacttatact cttacttcaa gaggaaaatg
    41161 aaaaaaaatt atttttggct gtttcttttt atttatcaaa taaggagtgg aaaaatgcga
    41221 gcagcagact tattgacaat tcttacaaaa tcacccaaaa aaacagagta tcaaggagtt
    41281 tttttggctc aagaacaaaa actggtgcct gtgacaatgg tccagataaa taaagcaaat
    41341 caatttatct ttttatttga acacggcaaa gcaccacttg ctatgaaaga catctttctt
    41401 tttttgatga agaaccgtga gaaagctgtt tattatcagt caaaagaaga actcattcct
    41461 ctttatggag tgaaagagat agaaaataaa gtggtgatat aagtaaaaat aagaaaacaa
    41521 gacgtttatg atgtcaaaac aaccattttt tacatttttg gcaaaaaagt gtcatgatac
    41581 agtataatat tcgttgaaca ggccaataaa ggtgttctcc cccacgagat ttctacttta
    41641 ttggctgttt ctttttatta aaataaaagt tgtgtgtgta aaaaagatat agctgattcc
    41701 aagtgacaat ttcgtataga tttttatggt attcgtagtg aaaaaacgag aaccaaaaag
    41761 ttgatccgac tttgttgctt ggattctttt tttgtcagca tatttagagg tatttttttc
    41821 ttttttttgt tcgtgctgta aggttaaggc aagacaagtt agttgggaaa aaggaaagaa
    41881 atgtttatac ttaaagaata acagaaagga aggtcgcatg aataatttta tacaaacatt
    41941 aagtgaaaga aaaggcgagt tgctggaagc tgcatttcaa catctgtcca tttctctcat
    42001 ttctttgctg attgcagcac tgattgctat tcctttagcg atttgggcag ccaatcataa
    42061 aaaaatggca gaagtcttat tgcagatcac gggtgtgctc caaacgattc cttcacttgc
    42121 cttattaggt ttacttatcc catttgtagg gatcggaact gttccagcat tgattgcact
    42181 tgttatttac gctttgcttc cgattttcca aaacacgtat attggtctag ctgaaattga
    42241 cccgtctatt gaagaagcag cggtagcatt tggtatgtcc agaatgagac gcttgctgaa
    42301 agtagagctt cccatcgcat tacctgtcat tatctcaggt atccgaactg ccttagtttt
    42361 aatcatcggt acggctactt tggcagcatt gatcggagca ggtggattag ggacatttat
    42421 tttgttaggt attgaccgaa atacacctgt tttgacattg attggtgcga tcagttctgc
    42481 cttgcttgca attatattca gcggactgat tcgctggttg cagcataaga aacctcgata
    42541 ttccatcatt actttagcag cagtggtgtg tttatttggc ggcgtttctt tatatcagtc
    42601 tgccttgttt aaaaatgaaa ccatcacgat tgctggaaaa ttaggagcgg aacctgaaat
    42661 cctgatccaa atgtataaag aattgattga agacaacaca aaaacagaag ttgaattaaa
    42721 accgaatttt ggcaagacga gttttttgtt caatgcactg gatcaaggtc aaatcgatat
    42781 ctatcctgag ttcacaggta ctgtcctaga aagcttggtg aaggtacctg aagcaatgaa
    42841 aagtgctgat ttgacaaaag aaaaaacata tgacgaagca gaagaattat tgaataagca
    42901 attcgatatg acattattaa aaccaatggc ttaccaaaat acgtatgcct tggcagtcaa
    42961 gagatctttt gcgaacgaac atcaacttaa aaagatttcc gatttggcag ctatctctga
    43021 tcagatcaaa gcgggattca cactggaatt tattgatcgt tcagatggat ataaaggaat
    43081 ccaagaagca tatggcttga atttttcaag tgtacaaagc atggagccaa gtttgcgtta
    43141 ccaagcaatc aataatggag atgtcaatat tgtggatgcc tattccacag atagccagct
    43201 caaggagtac gatctagtga ctctagaaga tgatcgaggg ttattcccag cttatcaagg
    43261 cgcaccgctg atgaaaaaag attttgctaa agaacatcct gaaatcgtta aagcactgaa
    43321 taaattaagc ggaaaaataa cagaggatca aatgattgat atgaattacc aagtcaatgt
    43381 cgaaaagaaa aagccgacag aagtagcacg aatcttcctg aaaaatgaag gattagtaaa
    43441 ggaggaagat cagtgactaa attaatcgag ttcaaacatg tgcaaaaaaa gtatgatgga
    43501 aagtatgtca tcgatgacct aaatctggca atcaaaaaag gagaaatctt tgttttggtt
    43561 ggtccttccg gtagtggaaa aacaactact ttgaaaatga tcaatggatt atctaaacca
    43621 tcagcaggag acatctactt caaaggaaaa tcgttaaatg aatataatct gcagaaaatg
    43681 cggtggaata tgggatatgt gctgcagcaa atcgctttgt tcccgaccat gacagtcaag
    43741 caaaatattg aagtcatccc tgaaatgtta ggttgggaaa agcagaaaag agcagaccgt
    43801 gtagatgaac ttcttcaaaa agttggctta tctcctgata tttatcgaga tcgtatgcct
    43861 agagagttgt ctggaggaga acagcaacgg atcgggatca tccgagctat tgctgcaagc
    43921 ccagatgtga ttttgatgga cgagccattt agcgcattag atccgatttc aagaaactca
    43981 ttacaagaat tggttttgtc cttacacgaa gaattgggca cgaccatcgt tttcgttacg
    44041 cacaatatgg aagaagcaat caagctaggt gatcgtattg catttatgaa ggatggagaa
    44101 attatccaat gtgacacacc agagcagtta ttgatgaatc ctaaaaacga ctacgttcgg
    44161 catttctttg atgaaccgaa acagacgaaa gagtggcgag tagaagattt agtcgtcaat
    44221 ggatatttct taaatgaaat accagaaaat gctcgtcaac aagtttgctt tgatacgcct
    44281 atgaaagaag tatattcgct tctttcggtg tatccaagca ttgtgatagt agaaaagcaa
    44341 agaagtattg ggtcgctgac aagtaaagaa atctttgctt ttttaagtcg agaggaggaa
    44401 ggaaatgaaa acatatgatg caatcatcat cggttcaggt gtgagcggct taagtgctgc
    44461 ttatggattg aaagaagcag gtaaaacagt actagtggtc gaagaagatc tatggggcgg
    44521 gacttgtcct aaccgtggat gtgatcctaa aaaagtcttg ttaagtgcag tagaggcacg
    44581 taatcgggta aaacaattga gtggaaaagg ttttaacgag atcccaactg ccaactggga
    44641 agaacttcaa aaattcaaac gaacatttac ggatccagtc ccagaaagcc gaaaaaaaca
    44701 attagcagaa gctgaaatcg atcatctttc aggaaccgct cgttttttgg atgattcatc
    44761 tattgaagtc aacgaagaag tcttccatgc ggattactta gttttggcaa ccgggcaaag
    44821 acctacgatc ttaccagtgg agggaaagga atacttgaaa actagtgcag actttttatc
    44881 attgcctgta ctgcctaaag aaatcatttt tatcggtggt ggttatattg cttttgagct
    44941 agctacgatt gccaatgctg cagggagcaa agtaaccatt gtccatcata atcaacggcc
    45001 attaaaagaa tttgaggcgt ctttggtaga ggaagccgtc catcaaatgg aagcatctgg
    45061 cattcagttt gcttttggtg ttgaaaccca aaagatcatt tcagaaggta ctcgctatcg
    45121 tttagtcgga aaagagacgg aattagtagc agatatgatt ttttgtgcga ctgggagaca
    45181 gccgaataca gaatctttag cacttgagca agcgaatatc gtctttgata aacacggaat
    45241 tgcagtcaat gattatctgc aaacgagcaa tccaaaaatt tttgcgtgtg gagatattgt
    45301 ttcaaggaaa accccaaaat tgacaccagt cgccactttt gaaggaaatt atgtagctaa
    45361 gcggataacg gatgcaacaa gcgaacctat caaatatccg attataccta cgatcgtcta
    45421 cgccagtcct aaacttgctg aagtaggagt tacaaaaagt cacgcctctt cgtcagatca
    45481 agtggtagag atggatctta ccagttggtt cacctatcat cgtgtcaatg aaccagttgc
    45541 taaggctgaa ttgacctttg accagcaaaa ttatttgatt ggtgctgcag tgattagcga
    45601 gcaagcagac gaattgatcg atgatttgac actcgtcatc aatcaaaaat tgactaaaaa
    45661 agagttggat agctatatca tggggtatcc gacattggca agtgatctct cctatttatt
    45721 gaaataatca gcatgataac taaagcgctt gttgcttttt ccttcttgtg ctacacttta
    45781 aaaaatgaat acctgtttct ggggatgtcg tagacgacat gagagtaagt tgtgaactta
    45841 gacccattga acctgtcagt taatactggt gaagggagaa acatagcaga cgcttgaagc
    45901 gggttactat gtcgtgccca tttcaagcgt tttttgttat tcatattaga agaaaggagg
    45961 taacaaaatg aagaaaaatc tttatccagc agtcagtatg gcattcattt taattatttg
    46021 gcagattgtt gtcatagttt ggaaaatacc tgcctttatt ttacccggac ctgctgctgt
    46081 attttctgca ttagcggcag atgcacaagt attactttcc cattctgtca cgacattaaa
    46141 tgaagcagtg cttggtttgg taatagctag cgttctttct tttattactg ccttggcaat
    46201 ggattattgg aagtttttag aaatgtcttt ttatccgtta ctagtgattt cacaaatgtt
    46261 gccaatcatg gtgttagggc cattacttac cctatggttt ggtttcggta tgcttccaaa
    46321 agtgatcctt gttgtcttga taagctattt tccgatcgta gtttcttttt cggatacatt
    46381 gaggaaagta tcaaaagagc aaatcatctt tttgaaaacg atgggggcag atacagggaa
    46441 gatttatcga atatataaaa taccagcggg tttatccggc ttcttttccg gtttaaaagt
    46501 ggctgctact tattgtgtca gcggagcagt cgttggagaa tggctaagcg ctcaagcagg
    46561 cttagggtat tacatgatac gcgtaaaaaa cagctaccag atcgataaag tttttgctgc
    46621 gatcatttgt gtcattctat tgagtttatt gctgaatggc gcttgttcat tattgaaaaa
    46681 agggtattat cgtatgcttt atatttttta agagaagggg atcaaatgaa aaaattatgg
    46741 cttttattac cgctactgtt gcttttatcc gcttgtggca ctgcaaaaga aacaagtagc
    46801 aaacaagaaa taaaggattt gaaaaaagtg acacttgttt tggattatgt accgaatact
    46861 aatcatactg gcatctacct agcaaaagaa aaaggctatt ataaagaggc tggtttaaat
    46921 gtccaaatca tcgaaccagg agataattcg acaagtattg gtctagtagg tgcggacaaa
    46981 gcacaatttg gtgtaagtta tcaagaagat gtcacttatg ctcacgcaga tggacagaat
    47041 ataccagtca aagcaattgc tacagtgatc aaacataata cttctggatt cgccacccta
    47101 tcagacagta acatccattc accaaaagat tttgaaggaa aaacatatgc aggttggcaa
    47161 agtccaagtg aagaagctgt cttaaaagct gtgatggaaa aagacggcgg ggacttttca
    47221 aaactgacaa tggtaggaag caatggagaa gggccagaaa gcttaggaaa atcctcagat
    47281 atccaatggt actttgaagg ttgggatatg atcaaagcaa aagaagcggg tattgaacta
    47341 aactatatcc cattgaaaga attagatgaa cggttagatt actatactcc ggtaattatt
    47401 acgaatgatc aactgatcaa aagtgatcca gaattggtac agtcttttat ggatgccacg
    47461 aaaaaaggct atcaggaagc tattaaggat ccaaatgaca gtgctaaact gttgcaaaaa
    47521 tatgcaaaag aaaatgatcg gacgttttta gaagaatcac aagcattctt gtcaaaaaat
    47581 tatacggatg atcctgagaa ttggggattg atggaagaaa aagtttggcg caattataca
    47641 gcttttatgc aggaaaacgg attgatcaag caagatgtac cttcgcaaga actattcact
    47701 aatcagttta taaaatagga gtgatagata tgtcaatcca aatcagccac ttgaatgtag
    47761 tcattgaaaa cctgaaaata ttagaagaca tccatttcac tatccctaaa gataccttta
    47821 catcgattgt cgcgccaagc ggagccggta agtcaacatt gctgaaaact ttaacaggag
    47881 tccagcctat gacttctgga acgatcaaag tagacgatca aaaagtaact ggtctccata
    47941 cagcatttag ttatatgccg caagaagata tgttacttcc ttggctgagc gtctatcaaa
    48001 acgttacgtt atatcaaaaa atcaatcatc taacaatcaa tgaagaacaa gtaagggatt
    48061 atctggatat ctttgggtta aacggctatg aacatttttt gccggaacaa ttatctggcg
    48121 ggatgaagca gcgaacggcc ttgttacgaa caatcatgaa tccttcttct tacttgcttc
    48181 ttgatgaacc atttggagcg ttagatgcta tgaccagagg gcagatgcaa gactggatgt
    48241 tgaagctgcc taaaaaagca aagcggacta ctttacttgt gacgcatgat atcgaagaag
    48301 caatttattt atcagacagg attcttgtgc tttccgcccg tccggcacat gtgattgctg
    48361 agattcaagt gcctgaaaaa cgacggtcac gtgaatggct actgcagcaa tcagagttga
    48421 agcaaacgat ttatcagtta ttggcaggtg aattagatgt taagtgatgc tcattgtcat
    48481 ttagatggga gtcagagttt agcactcctt cagcaggaac acacgatttt gacgatcatc
    48541 aattgtgatt cgccagaaga atggaaggaa aacagacagc ttgcagcaag taagactcaa
    48601 gccttaagtt acggtatcca tccttggaaa gcagatagct atacgtttga acaagttgag
    48661 ccttttttga aaaaagcaag gatcatcggt gaaatagggt tagataatat ttggacgaat
    48721 gtaccgatga ctacacaaaa aaaagtattt gagcgacagc ttgcttttgc agccataaat
    48781 gagaaacctg ttgtactgca cacaaaagga tgcgaaaaag agatcttaaa ttatatccaa
    48841 gcttacccta atcactattt gatccattgg tattcttctt tggactatca acaagactat
    48901 attgatttag gctgttattt cagcattggt cttgatttga aaaagaatcc agcagtctgg
    48961 caactagcta aagcagtccc aatcgaccac ttacttattg aaacggatgg actacatgca
    49021 gcagagtggg ctttaggggg gattttttca gaaaaagatt atgtctcact gcttgaagaa
    49081 cagttaaaga caatcgctga gatcaaagag ctatcagttg aagaagttaa aaaaaatact
    49141 tatcaaaact tggaacgttt cattagatta ggtaaataaa aaagagatgt gacacaacta
    49201 gtgtcgcacc tctttttggc tttctttgta taaaagtaaa ctgtttgatt aataaatgaa
    49261 tcttagtacc aaccgtttgc ttcccagaat gctttcgccg cttcccaaga accataacgt
    49321 gaagtaacat attgttctgc tactctttct tggtttgcag cagagtagtc accatttaag
    49381 taagaagaat ctaattggta acgtccgatg taacgtccgt tcgttgctgt gtaagaaccg
    49441 cttgattctt tttgtgcgat ccattctttt gcagagcttg tgcttgctgg agtagcagca
    49501 gtttctgtta cagcaggagc aggttgtgtt tcagcaacag gcgctgcttg tttttccgtt
    49561 tgaaccgttt cttgtacaac aggttgttca gcttggactg gtgcttcttg aacggctgct
    49621 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg tt
//
LOCUS       DBBGRF010000019        48317 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000019 DBBGRF010000000
VERSION     DBBGRF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.019"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(38..1189)
                     /locus_tag="ACIZD4_001183"
     CDS             complement(38..1189)
                     /locus_tag="ACIZD4_001183"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGC5990132.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="ACIZD4_001184"
     CDS             complement(1202..1639)
                     /locus_tag="ACIZD4_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC5990133.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="ACIZD4_001185"
     CDS             complement(1654..3420)
                     /locus_tag="ACIZD4_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGC5990134.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="ACIZD4_001186"
     CDS             3684..4361
                     /locus_tag="ACIZD4_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGC5990135.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="ACIZD4_001187"
     CDS             4364..5491
                     /locus_tag="ACIZD4_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990136.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="ACIZD4_001188"
     CDS             complement(5691..6131)
                     /locus_tag="ACIZD4_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC5990137.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="ACIZD4_001189"
     CDS             complement(6142..8175)
                     /locus_tag="ACIZD4_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HGC5990138.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9878)
                     /locus_tag="ACIZD4_001190"
                     /pseudo
     CDS             complement(8177..9878)
                     /locus_tag="ACIZD4_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            complement(9972..10922)
                     /gene="manA"
                     /locus_tag="ACIZD4_001191"
     CDS             complement(9972..10922)
                     /gene="manA"
                     /locus_tag="ACIZD4_001191"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGC5990139.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10961..11986)
                     /locus_tag="ACIZD4_001192"
     CDS             complement(10961..11986)
                     /locus_tag="ACIZD4_001192"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC5990140.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12195..13064)
                     /locus_tag="ACIZD4_001193"
     CDS             complement(12195..13064)
                     /locus_tag="ACIZD4_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC5990141.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13523..15415)
                     /locus_tag="ACIZD4_001194"
     CDS             complement(13523..15415)
                     /locus_tag="ACIZD4_001194"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990142.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15412..17139)
                     /locus_tag="ACIZD4_001195"
     CDS             complement(15412..17139)
                     /locus_tag="ACIZD4_001195"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990143.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17155..17805)
                     /locus_tag="ACIZD4_001196"
     CDS             complement(17155..17805)
                     /locus_tag="ACIZD4_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HGC5990144.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18009..18305
                     /locus_tag="ACIZD4_001197"
     CDS             18009..18305
                     /locus_tag="ACIZD4_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGC5990145.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18477..19097
                     /locus_tag="ACIZD4_001198"
     CDS             18477..19097
                     /locus_tag="ACIZD4_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGC5990146.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19189..20355)
                     /locus_tag="ACIZD4_001199"
     CDS             complement(19189..20355)
                     /locus_tag="ACIZD4_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC5990147.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20367..20720)
                     /locus_tag="ACIZD4_001200"
     CDS             complement(20367..20720)
                     /locus_tag="ACIZD4_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HGC5990148.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20848..21870
                     /locus_tag="ACIZD4_001201"
     CDS             20848..21870
                     /locus_tag="ACIZD4_001201"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGC5990149.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21889..22050
                     /locus_tag="ACIZD4_001202"
     CDS             21889..22050
                     /locus_tag="ACIZD4_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990150.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22309..22743)
                     /locus_tag="ACIZD4_001203"
     CDS             complement(22309..22743)
                     /locus_tag="ACIZD4_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990151.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22853..24712)
                     /locus_tag="ACIZD4_001204"
     CDS             complement(22853..24712)
                     /locus_tag="ACIZD4_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC5990152.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            24713..24853
                     /locus_tag="ACIZD4_001205"
     CDS             24713..24853
                     /locus_tag="ACIZD4_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HGC5990153.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(24830..25990)
                     /locus_tag="ACIZD4_001206"
     CDS             complement(24830..25990)
                     /locus_tag="ACIZD4_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC5990154.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26297..27721)
                     /gene="araA"
                     /locus_tag="ACIZD4_001207"
     CDS             complement(26297..27721)
                     /gene="araA"
                     /locus_tag="ACIZD4_001207"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HGC5990155.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27737..28435)
                     /locus_tag="ACIZD4_001208"
     CDS             complement(27737..28435)
                     /locus_tag="ACIZD4_001208"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGC5990156.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28392..30053)
                     /locus_tag="ACIZD4_001209"
     CDS             complement(28392..30053)
                     /locus_tag="ACIZD4_001209"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HGC5990157.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVSGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30271..31671
                     /locus_tag="ACIZD4_001210"
     CDS             30271..31671
                     /locus_tag="ACIZD4_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HGC5990158.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31923..33002)
                     /locus_tag="ACIZD4_001211"
     CDS             complement(31923..33002)
                     /locus_tag="ACIZD4_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5990159.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33088..34047)
                     /locus_tag="ACIZD4_001212"
     CDS             complement(33088..34047)
                     /locus_tag="ACIZD4_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HGC5990160.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34059..35570)
                     /locus_tag="ACIZD4_001213"
     CDS             complement(34059..35570)
                     /locus_tag="ACIZD4_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HGC5990161.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35592..36155)
                     /locus_tag="ACIZD4_001214"
     CDS             complement(35592..36155)
                     /locus_tag="ACIZD4_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGC5990162.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36161..37024)
                     /locus_tag="ACIZD4_001215"
     CDS             complement(36161..37024)
                     /locus_tag="ACIZD4_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990163.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37038..37934)
                     /locus_tag="ACIZD4_001216"
     CDS             complement(37038..37934)
                     /locus_tag="ACIZD4_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990164.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38109..39398)
                     /locus_tag="ACIZD4_001217"
     CDS             complement(38109..39398)
                     /locus_tag="ACIZD4_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5990165.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39370..40887)
                     /locus_tag="ACIZD4_001218"
     CDS             complement(39370..40887)
                     /locus_tag="ACIZD4_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HGC5990166.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41085..41975
                     /locus_tag="ACIZD4_001219"
     CDS             41085..41975
                     /locus_tag="ACIZD4_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HGC5990167.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42048..42872)
                     /gene="nadE"
                     /locus_tag="ACIZD4_001220"
     CDS             complement(42048..42872)
                     /gene="nadE"
                     /locus_tag="ACIZD4_001220"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGC5990168.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42884..44356)
                     /locus_tag="ACIZD4_001221"
     CDS             complement(42884..44356)
                     /locus_tag="ACIZD4_001221"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGC5990169.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44993..45355)
                     /locus_tag="ACIZD4_001222"
     CDS             complement(44993..45355)
                     /locus_tag="ACIZD4_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGC5990170.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45578..46330
                     /locus_tag="ACIZD4_001223"
     CDS             45578..46330
                     /locus_tag="ACIZD4_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC5990171.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46470..47393)
                     /locus_tag="ACIZD4_001224"
     CDS             complement(46470..47393)
                     /locus_tag="ACIZD4_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5990172.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47408..47680)
                     /locus_tag="ACIZD4_001225"
     CDS             complement(47408..47680)
                     /locus_tag="ACIZD4_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990173.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        14090 a        10033 c         8324 g        15870 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgagt ttgtgagaat
     9241 tcgattccta aaggtgtcaa tacaccatga ttgattgcat tattgaaaaa tagtactttt
     9301 agaggttcta agatcagact gacaagtggt aacagattca ttgtgactag ccaagacaca
     9361 acggaggcga gcaacaagtg aacactattt aaaactggtt caataaaaac gattccaatt
     9421 atacaaataa cgctaccagt cagtcctact agtaggttgc tgacaagcat ttcatatcca
     9481 gccttgaatt tcacgtggaa tctagaaaca aattgttcat atacgatgcc ggcaagcggc
     9541 ccgataatca tcgctcctac gatttgtgga gcattggaac gagcgatcaa ccctaaagaa
     9601 gcaattgcac cggcgactgc ccctttttgt ccccctaccg atttcccgcc tgaataactg
     9661 atcaagatgg gtaaaagcag ctggatcatc caatggcata cctcttctaa tgtggtgtgc
     9721 aaatcgccag acacaccttt tgttgctaat gacaagattc cccaagcgat aaacagactt
     9781 agatttggca tgatcatttc atttaagtga tgtccagctt ttctcagttg tttcatagac
     9841 acgcgactgc tgttgtttgc tttccatttg tattccatct ttttcaccat acttctattt
     9901 attgatggac ggattttatg tagaaaaagc agcaaacgaa aaaccgtctg ctgctttcag
     9961 ctatctggga actatttgcc tggttcagtc gcaatgattg ctagttcacc ttggaccgcc
    10021 cactcagaaa cgccatttgg aataatacag cttgttcctt tttctaatgg atatgttttt
    10081 ccgtcaacga caaggtctcc tgctccttcg attaccgtca tcaatgtata aggggcttgt
    10141 tttttgaaag atgtgattcc tttaatatcc cactcatata cattgaaaaa ctcagtttct
    10201 aaataagtga cgatcgatga attccctttt cggacttctt tgatttgtaa ttctggtgtt
    10261 ttcgcaggga cagttgttac atcgatcgat tgttggatat gcagctctct tgtttgtcct
    10321 tgcgcatctt ttctgtcgta gtcatacacg cggtaagtcg tgtcagaact ttgctgtgtt
    10381 tctaaaatca tgattccttt accaatagca tggatcgttc cgcttggtac ataaaagaaa
    10441 tcaccttttt taactggtac tttcttcaaa aggtcatccc agcgcccatc tttgatcatc
    10501 tcagctagtt cttctcttgt ctttgcatga tgaccataga tgatttctgc accaggttca
    10561 gcatcgatga tataccagca ttcagttttt cctaattcac cttcatgttt catcccatag
    10621 gcatcatctg gatgtacttg tacagataga tcatcttctg cgtctaagat cttgatcaat
    10681 aatggaaaca ctggttctga aggatggcca aacaattcct tgtgttctga ccatagttca
    10741 tctaatcttt tccctttgaa ttcgccattt tctactacac tgacaccatg aggatgcgca
    10801 ctgatcgccc aatcttctcc gattttatcg ttagggatat caaaaccaaa gactgaacgt
    10861 aaacgacttc ctccccaaat tttttcttga aaaactggtt ttaaaaacat aggttcctgc
    10921 ataattcaaa ctcctctcat ttttcatagc tattatagca ttatttcggt aataccgctt
    10981 tctctttcaa aaagttttca acaatttcat ctcgacatat gagatactcc gcacgatgat
    11041 cgacaggatg tacgcgattt gacaaaaata tcaacgcttc ttgtgttttt atatcaatca
    11101 agaaaaacgt acctgtataa ccagtatgaa aaagaatcgc atgaccgtct tctacatcct
    11161 tttttaagtc ccatcctaaa gaacgatagc catttttttt cggtgtttga tcttgcagta
    11221 aagaatcaat cgtctcttct tctaaaaaac gaccattacg gatttttccc ttgttcaaat
    11281 acatttggac aaaagtaatg ctgtctttca aatcaataaa gagacccgcg ttacctgcat
    11341 gttcagccaa aactcttgct ttcggatcat gagtttgtcc acgcaaaacc tcacccgaag
    11401 gcagttgttc tgtgggaacg atttttttgg aaggaaaagg aagaaataag ctgttcatca
    11461 ttcctaatgg ttccaatact tgttcttgaa agatttccac tgcagtttct tggtaaattt
    11521 cctctagcat caacccaaga agaatcgtac cggcatctgt atattttact tcttttccta
    11581 gttgctcacc tggttctagc ttcaaataag cggcgatcaa ttcttcctga gatagcttat
    11641 ctctgtttgg tatccatgtt ttgatatcag aagtatgtgt cagtaaatga cgcaaagtga
    11701 ttgtctgatt ttcaaattca ggaagatatt tatgaagcgg ttgatcgagt tctatctttc
    11761 catcttctaa tagacgtaaa actaatgaag tggttgcaac gactttcgtc agtgaggctg
    11821 catcaaacaa cagatcttct gtcatcagct gcttttcagg aacgacttgg gcaaagccgg
    11881 ctgtaaatgt ttctacttga ttttctttta tgaaggcgac tgctacacct ggataaaatc
    11941 cttcttccat ctttttcaaa ataagctgtt tcgtgtgtgg atacatcttt ttctcctgct
    12001 tttctatcag attcttacag tccaagctta aagcttaatc tatgaggaat caaccttttt
    12061 tacacaaaaa aactgcgcga aaaaccgcgc agtttccccc ggtatactat tttctctttc
    12121 tatctctaga ataagcgata gtatgaccgt tcataaaatg acgagacatg cgacaatcgt
    12181 taagaaagaa aaagttaagc gtcgcatcga atgtcagttt tattcttttc ttttggctca
    12241 ctgacgaacc accattcgat tcctatagca tcatagattg tgagtactgt gtgctttttg
    12301 tctaagaaga aatcaactga tagttgctgc aagtgagcaa tcagtccttc catgctttca
    12361 gtatcgatca tgaatttcag aaaatcaagt ccaatcactt catctgtagg caaatcaatt
    12421 gcgcctccgc tagcttctgt caaaccaaca tggaaatctc cttcattcaa tacatggatg
    12481 ccctcttctt cattatgtac cttcaaacca agtacatgat taagaaattg gcgttctttt
    12541 gttaagttag taacatttaa atggattttt tcaaaataag aacctgttga tagtttactg
    12601 aatttttctt cagattttct taataatgct tcttgatcca ttgtttctgg aatttctctt
    12661 tggtcgttct tattctcttc atggtaaatt tccaattcat tctcttctgg gtctacgagc
    12721 aaaatcccca tacgtccatg atcttctaaa gcttctttga ttggataatt cattttacgg
    12781 atacgacaaa ggatatctgc catttcttct gtgctaggga taatcaatga aaaacggttc
    12841 agctttttga tcacccccat gtgatcattc gctctaggac tttcttccag cagcaacatt
    12901 tcacttccag cttcttctgt tcctaaaatg gctaattcgt tttcttctct tttcaaatca
    12961 aagccaacaa cgttcttgta aaaatcaatc attttatctc ggtctttcac ccgaatggct
    13021 acacttttta aataggtggc agcccccaat tgaaaatctt tcatatttct tgctcccctc
    13081 tacgtcaagc tttattttaa cgatggattc ttcttctttc aagcaataac tttgattttg
    13141 ttaaaaaaaa tgtgagaaaa ttcgcatttt gcttgttttt tgtaaattaa tgagtaaaaa
    13201 ctcttataaa aagaggttgt gaaaaagctg ttctgcatca agtaataaga acagccaaac
    13261 aaaaatagct cctcctattt ttcgtttggt tgggcttatt accgcagatg caagcttttg
    13321 aacaccgttt aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa
    13381 aacggaaaaa tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga
    13441 ttgaacaccg tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa
    13501 aaaataataa atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa
    13561 gatctgcata gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg
    13621 aaccatgatt catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa
    13681 caacgaaact tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg
    13741 ttcgtgtatc tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga
    13801 atgcccgcgc aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt
    13861 ttaatacagt gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt
    13921 tagcagcctc aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat
    13981 agatacttcc tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt
    14041 catcacgtga aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat
    14101 cgtagaaccg ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa
    14161 tagcgaccat ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg
    14221 gtgtgtagcc gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg
    14281 gaaggccaga tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg
    14341 ctgaagcaac tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag
    14401 agaactgtgt tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg
    14461 caacttttac tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca
    14521 tcaacggcat gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct
    14581 gattttcttt ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg
    14641 tatgaccacc atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat
    14701 ctgcgaaaaa cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga
    14761 tcatcaataa cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc
    14821 caatcaatgt gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga
    14881 tgttatccat atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat
    14941 aggaaatcgg tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc
    15001 gttgggaaac acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat
    15061 acatcacgat tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg
    15121 ttacttgttg gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg
    15181 tggttgcttt ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta
    15241 gtacaaatac agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta
    15301 ccgttcccca gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac
    15361 catgtcctgg accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa
    15421 gtcctcctct cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag
    15481 ttcttcatgt gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc
    15541 atccattact gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt
    15601 tttcaatgct tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc
    15661 aaacacatag atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg
    15721 tccaccagag aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc
    15781 tgaaacaaaa tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc
    15841 atccggctta ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg
    15901 aggaacaaag cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc
    15961 atttatttgg atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt
    16021 cgttttacct gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa
    16081 atcaatatct tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa
    16141 ggccaatgtt gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat
    16201 accgattttt tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac
    16261 catgataaaa atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat
    16321 aaatgcaatc agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca
    16381 agtgattgct acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac
    16441 gatcgtatta actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt
    16501 ttcttcaaag cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg
    16561 aaataccagg tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa
    16621 gtacatgatt ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt
    16681 caactgatga tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt
    16741 gatcatcata cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt
    16801 tcttgtgatc aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga
    16861 ttttttatag acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa
    16921 aaatgtattt gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc
    16981 tgtatgccaa atataatcga catctccttg cgctacccct ttatcaataa tattggaggt
    17041 aagtgtcggc aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat
    17101 tgctgaagtc aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt
    17161 atatactccg tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac
    17221 tgagtaatct tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt
    17281 attcatcact aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt
    17341 ccgatcgatc aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg
    17401 aggcgttttt tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt
    17461 cataaacaag ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt
    17521 agaaaaatag gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa
    17581 catatcttta gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt
    17641 atcttcaaaa tactgataga aactgcctct agggatatcc gctaatttga cgatattagc
    17701 aatcgaagct tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct
    17761 tttttgtttt tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga tcctcctttc
    17821 tttcaagatg acacattgtc atatgacgct gtgtcattat aacacctcct acctgttttg
    17881 caagacattt gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga
    17941 atccttccat ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga
    18001 tgagataaat ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg
    18061 acagcatcgt tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact
    18121 cgctttctat ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac
    18181 tttattatat tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg
    18241 ctaatggttt tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg
    18301 cttgaatatt gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct
    18361 tttataccct gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc
    18421 cttttctttt tctcatagtt ataacaatca tagcaataaa aggagaaggt aagcatatgg
    18481 catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc acagttaagg
    18541 cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa gtgactgttt
    18601 tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca ggttgggaag
    18661 cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa aaaattgctc
    18721 gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc gcaaacgcct
    18781 tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc aatgtagctg
    18841 gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt aaaaaagcac
    18901 tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct caatatgtaa
    18961 aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc gaaggaatcg
    19021 attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa gctgctgctt
    19081 taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag gaaaaaatct
    19141 tcaaagcagc atttgtacct tggatatttt cccatctgtc tctttttgtt attctttctg
    19201 ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt caaaaacatg
    19261 agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac cgatgattcc
    19321 gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga ttgctaactg
    19381 attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta ctgcaaaaac
    19441 gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga tagccggaat
    19501 catcgctaaa aatgatccta agtaagggat caggttcaaa aaacccgcaa taatccccaa
    19561 cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga ttgccacagc
    19621 aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca tttcactcag
    19681 cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat aaggtgctaa
    19741 ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca gagccactaa
    19801 aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct tagatatatc
    19861 ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca actgttcgcg
    19921 aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa tcgtatctac
    19981 atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag ggatgatcac
    20041 tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga tactgtaaag
    20101 ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt aatacaagat
    20161 tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg gtgcaaacaa
    20221 atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa caagtaaggc
    20281 tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc tgttcttctt
    20341 attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc caaaccaata
    20401 gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc ttctggacaa
    20461 gcatcaaaaa tcaatgatac gtgagctact gtctctaaat tcccattggc catcggaccg
    20521 acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc tttcaaagaa
    20581 aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc agctgttgct
    20641 gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt cccaatttct
    20701 gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa cagtataaca
    20761 cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg aaaactattt
    20821 cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg aacctatacg
    20881 cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga agaattagcc
    20941 aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag taaagctggc
    21001 aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta cgataaggat
    21061 tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt agcggttgat
    21121 gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa tgtctaccat
    21181 atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga agcgacaggt
    21241 cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc tgaccaacga
    21301 ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc cgaaaacggc
    21361 aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg ccatcttgtc
    21421 tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac agtccgcgtg
    21481 ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc gaccttgcca
    21541 gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga tggcaagttc
    21601 ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt tgaagatggt
    21661 tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg cgatttcgca
    21721 ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa tctgacatta
    21781 tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt ctatgtacca
    21841 gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat gaatcagcaa
    21901 gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg gaaaatcgaa
    21961 gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca gaactacttt
    22021 gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg aaaagaacat
    22081 caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa accgccgaga
    22141 tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca aggttgttgt
    22201 tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa aggtaatatt
    22261 acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt attttttcaa
    22321 caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt ggtcttgttt
    22381 tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga tactttggat
    22441 catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt tatgaatgcc
    22501 cattgctttt gctggtggac gcaaagtact gactttctta agcattgccc gatatttttt
    22561 tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca gttcacttgt
    22621 ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc cttctccgat
    22681 tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa tattcggtaa
    22741 catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg tttttatcct
    22801 caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat tcttattcgt
    22861 gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca tattggatca
    22921 attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct ttataccact
    22981 gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct aatgataaaa
    23041 gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc gctgcaaaat
    23101 aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct ttactgtcga
    23161 acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg atcgtatctg
    23221 aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta gaaagattct
    23281 tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct tgcagataat
    23341 tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct agattatcat
    23401 actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac tgaggtgttt
    23461 tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa atatatggat
    23521 tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg tcaaatccta
    23581 atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg atcgctgtcg
    23641 tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc atttttggta
    23701 caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa aaaccagtca
    23761 atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc atattgccac
    23821 tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat acttctacgc
    23881 cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg ttcggcgact
    23941 cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca gtgatttctt
    24001 tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc agattgtaca
    24061 aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa ggtatccata
    24121 gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa ttactgatat
    24181 accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg aatcgccttc
    24241 cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt cctgcggcag
    24301 ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg atttcagtga
    24361 tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc atataatttg
    24421 caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg acagatcctg
    24481 ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag aagaattttt
    24541 ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca ttttgacacc
    24601 actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt gctgctgttc
    24661 cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc aaatgcttgc
    24721 tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta cgaaattcga
    24781 aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt tatggccttt
    24841 ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc tgttgtttca
    24901 cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag acatgctcat
    24961 tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc agagaaaata
    25021 tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac ggcgcttgga
    25081 aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac aaaagataat
    25141 cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga gtcgatcccc
    25201 ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct ggaaaatcag
    25261 tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat ttatcaacaa
    25321 tttcacttct tcctacattg ataagtacag catctttttt cattttttct atattcgcct
    25381 gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg taatccgagg
    25441 tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca tcgcggatag
    25501 aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt gtgcctatcg
    25561 ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca taagcacttc
    25621 ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc atacgacttg
    25681 cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct tttactgcat
    25741 tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct ttttcaacgt
    25801 tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt gtaagccatt
    25861 catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca tctattattt
    25921 tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca atcaaatgaa
    25981 cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc aattagacaa
    26041 ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt aggctgagtg
    26101 ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag caaaatattg
    26161 agggtgagat atcttgataa atggtgttcc gttagctgac attgataata agactaaatt
    26221 tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa ctaagtggct
    26281 ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat tttgcccacg
    26341 tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg ccacctgcct
    26401 gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac acacgtgcaa
    26461 caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg atcagcagtt
    26521 tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct ttcccatcaa
    26581 atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca acgattcttg
    26641 gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag attgcttctt
    26701 ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc cctcgagcca
    26761 tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca gcaaaaccgt
    26821 atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt ccatacaggt
    26881 cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg cgaataccga
    26941 tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca taatcaccat
    27001 agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct tcgtctgata
    27061 cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc caaccaaatt
    27121 gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg ttgtcaccaa
    27181 aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc atccaatcag
    27241 caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta ttttgtttat
    27301 ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga tttaaattca
    27361 tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta gctaaatgaa
    27421 gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt gagaaagtat
    27481 gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc atgatttttg
    27541 tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc aattggccat
    27601 tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc agtgcttctt
    27661 ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca atattcaaca
    27721 taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg tgttttcgta
    27781 aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg agctgtctgg
    27841 taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc gcactttgcg
    27901 catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga attgctaagg
    27961 gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca tattcgtacc
    28021 cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca taaaaagtat
    28081 ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag atcgtcgccc
    28141 atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat aaaacagcat
    28201 gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg tccaagtcca
    28261 caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt ttgataacga
    28321 aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg acgagtccgt
    28381 gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc agcattttct
    28441 atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat cccctcacgg
    28501 taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt gatggtgatt
    28561 ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt cccatgtcga
    28621 tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc ggctgtgtcc
    28681 atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac ttctggtgtt
    28741 ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga tttcaatata
    28801 tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat gaaattcgct
    28861 aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt tactcctgta
    28921 atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt atcgccttct
    28981 agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat acccaaagaa
    29041 ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca gttattcgta
    29101 tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc cggatggaca
    29161 ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc cgaaatgttc
    29221 cctgtccgtt tggctacact gttcgtagcg accataccgg ttcctgcatc cccttctggc
    29281 ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata agcccctgat
    29341 tcgcttaact tgccagcttc ttctcctgat actagaactt taggcaaaat gtgatccaag
    29401 tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat ttcttgatgg
    29461 taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac gcctagtact
    29521 ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa attaatttct
    29581 ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact ccatctctgc
    29641 ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt gattgtattt
    29701 cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag ataaccgtgc
    29761 atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata gatttcgaat
    29821 acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc ttctaatgaa
    29881 taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc ggcaatagga
    29941 gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc aatccctaaa
    30001 gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt cataatgatt
    30061 taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc ttacaatgat
    30121 tattgtatac ttttgtacgt acatgtcaag cggttattta caagaataca ataaaaaaca
    30181 cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg atcaaccgcc
    30241 ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt ttcctcatcg
    30301 tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat tggtgttatg
    30361 accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc ttctttgata
    30421 ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt atctggtctt
    30481 ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat ttttatggct
    30541 ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat tgcagcaagg
    30601 attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta tatgtctgaa
    30661 atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat gattgcttct
    30721 ggcatgctcc tttcctatgt tgcagattat ttgctaaaag tgttgcctga aacgatggct
    30781 tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt cggtgtttta
    30841 gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga ggcaaaaaga
    30901 gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca aatccagctg
    30961 aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt agaaaaatat
    31021 cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca aggagctaat
    31081 gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc agcgagcgat
    31141 gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt gctctttttg
    31201 gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag cgtgatggga
    31261 ctttcattca tcctaccagc tgttttagga actgtactgg atgctcatac aaattcgttg
    31321 ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg ggctccactg
    31381 acatgggtaa tcataggcga aatattccca ctagctgtcc gcgggcgagc atctggccta
    31441 gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc tgtgatgact
    31501 gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt tttaggggtt
    31561 ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga aatcgaacaa
    31621 agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta aagaggttgt
    31681 gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag tcacaaggaa
    31741 caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac cagttggtag
    31801 gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc gatgacaaaa
    31861 gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta aaaacccgtc
    31921 tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc atagagaata
    31981 tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc atcttgtccc
    32041 aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg gcttaaagaa
    32101 gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt ttctgtcaac
    32161 ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc taaagcttgt
    32221 tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc cgtggtgaaa
    32281 gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct gataaaacct
    32341 ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag acgctgatgt
    32401 ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc taaacaaata
    32461 taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat gccttgttct
    32521 ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt aggctcaacg
    32581 atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc caattcgtga
    32641 tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc attttcgatt
    32701 cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac accgatcgtt
    32761 tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata tgtgcccgac
    32821 cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg ccgaatcgta
    32881 tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt tgtatttact
    32941 tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg atattttgcc
    33001 atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg caaggtttat
    33061 tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt caccaaattc
    33121 tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat taggattgtc
    33181 taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa tatcaaagca
    33241 cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat ttttttcaga
    33301 agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa gattcttgtg
    33361 ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac cagaatacgt
    33421 aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg aaaaaccccg
    33481 tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta acgtccaagg
    33541 attatccatt tcggatagat aaagattaga attcccagta atttcaggat cttgttgggc
    33601 ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac tgaaagtttc
    33661 ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat ctatatgctg
    33721 attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt tatgattgct
    33781 tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg cccagatcaa
    33841 ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag catgttctaa
    33901 ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa ccgatcctgt
    33961 aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt gccgaacgat
    34021 aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt tattctaatt
    34081 acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc tattgaaaaa
    34141 tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc caacagatcg
    34201 ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg ttcaatcgtt
    34261 atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt gccgttatct
    34321 acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata aacagggcaa
    34381 atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg catcacataa
    34441 taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg tattgtgttt
    34501 actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat agccagccct
    34561 aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat gggactaccg
    34621 acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc atcaaacgct
    34681 agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt agcaacgatt
    34741 tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt atcatcacgc
    34801 tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata gttatgcaaa
    34861 gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca ttcagggtac
    34921 gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc atccactaac
    34981 ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact cttagccccc
    35041 acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc aaaaggcttt
    35101 ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa attacaatat
    35161 tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt gaatatcggt
    35221 ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga atttggttct
    35281 atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc tacagtatcc
    35341 acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc taattctaat
    35401 tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt ttcatggccc
    35461 ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga gccaaacagc
    35521 cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac ttcttcgtcc
    35581 aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag tttccatacg
    35641 ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac aaatcctaat
    35701 aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca tgcactttgt
    35761 tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat ccaggataaa
    35821 agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac gattgtctgt
    35881 tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact aaggaacaag
    35941 ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt tcctgatccc
    36001 tcacctttcc attgcgccat tacataaaaa acagcacatg tagcaggcac gatagtaata
    36061 acaggcaaac acacgattac ccagagaata cctaataaga tgtaatcaga aaccacaatc
    36121 aactgtccat aaaatttagt ctcaactatt ttcatcttcc tcactctttc attccagaca
    36181 tagctgttcc ttgaacaaaa tatttctgtg caaaaatata aaccactagt aatggcagca
    36241 ttgaaataac cgttccagcc attacaggtc cataaaaaga aatgttctgc cctgtaaata
    36301 aagctaaccc tgctggtaaa gttctcattt ttgaactact tgtcaatatc aatggataaa
    36361 gcaagtcatt ccaactattc atcagcgtga aaatccctaa tgataaaaga gtaggtttgc
    36421 tcaatggcaa catgattttc aaaaaaatat taaactcact taatccatca atgcgtgctg
    36481 cctcttccaa agaatctggt aaagtaataa aaaaggaacg catcatgaag ataccaaatg
    36541 cagttgtcat acgaggaatg atcaaacctg cataagtatc aagcatgcca agcaaattga
    36601 cttcaataaa tagaggaatc atgaagactt ggaatgggat catcattgtc agcaaaacga
    36661 aatagaacaa aactgatttt cctttgaaac gcatacgagc aaatgcatac cccgcaagag
    36721 aatcaaagaa tacagaagtg atcactgtcc ctccagcaaa aatcactgta tttttgatgt
    36781 aatctaataa agggatcgtt gtccaaacct taatatagtt atctagggta tagctatctg
    36841 caaatattct aggcggaaat gagataatgt ctttttcgtg tttaaaagaa gaaataatca
    36901 gccacaaaaa aggaaacgca ataaccaaca atataactag catactaatc gttcgaatga
    36961 tttttttacc actaactgct tttcgactat tcacagtaac tgtaatcgag ctttctggtg
    37021 ccatacaggt ttccctccta tttcatttgt ttttctttcc gtgacatgta cacattagtg
    37081 gagatagcta tagttgcaac aatgataaac aaaaccgaag acagtgctga tgcatagccc
    37141 aattcataag gtgctgtaaa tcctcgactg taaatatatt gaacagctgt ttctgtctta
    37201 aattgtgggc caccagcggt tgcaacatat acttggtcaa acacttgcat cgaaccaatc
    37261 agattcgtta aaatacaaaa acctaaggag ggaacgatct gaggtagcgt aatgttaaaa
    37321 aactgctgtc gatttgttgc accatccatt tgagcagatt catacaaaga gggagagatt
    37381 ccctgaatag cagtcaagag aatcgtcata gtaacaccaa aattcttcca aacagtcatg
    37441 atggctaccg tcggcatagc aagggttgga tcgcgaaaaa attgagggat cggcaagccg
    37501 acttgtgaaa acaagtaagg aatcgcccct acattcggat caagcaacat agaaaaaata
    37561 atcgcaattg acgtcaatga acaaataact ggaatgtaaa atgtcgaacg acaaaaacga
    37621 ttgaatctgg tatttttaga taatgctact gctgctaata aaccaacgat aatttgtgtt
    37681 ggcgtttcga gtacggtgaa atataaagaa tgaatcaacg aattaactgc tcgttcatca
    37741 ctaaatatac gtgtgaaatt ttcaaaactt acaaaatttc ttgatgtaaa gaaaatattc
    37801 aaatctgtaa aactaatagc aaatgttcct aaaagcggta tgacagtaaa taataataaa
    37861 actaaaaaag atggagttaa aaacaaatac gcagcacgat caggacgatt ccaatatttg
    37921 gtgaatccgt tcatatagtc cacctcatct ttcattttga taaaatatac aatcttggtt
    37981 taaacgaatc tgaataagat atccgaacaa tcgctgtgat ttttgcaata acacctatct
    38041 gcaaatacta ggtcgatcat tcagatatct gtatcttgcc aacagtctat cctgtataaa
    38101 gttctgtact atttttgcag taattgattg atggcatcat ctgcatcgtt catgagtgtc
    38161 tcaggatctt ctcctgctaa taatttttca atcagtggat tgatgatatc gttattgatc
    38221 gcagagattt gggtaaaacc tggtaaatat ggctctgcat agtccatttg tttcgataat
    38281 tcagatacaa taggatcatt ttttacttct tcatcttttg ctactgaatc caagtaggca
    38341 ggaaaaccat tttcgatact ccatttttta ccaatttcag ttgtattcca atatttcaaa
    38401 aactcataga cagcttcttt tttattatta tctgtacttg ccggaatggc atatcctacg
    38461 ccatctaaaa tagctgtttt tttgtctgaa tcactccctt gtggtaaggt agtcacatta
    38521 taatcaatct cgtttgcttt caatccgtta tttaaccatg gcccattgat ttcaatggct
    38581 agttgaccag cattcattaa attgtccatt tcggcgccag aaatcgattc tggaccagtc
    38641 ttgtctacat ggatcatttt ttggatcgct tttaacgttt taaggttctc aggagacgca
    38701 aattcagact tagtataatc atcgttcact aatttaccgc catttgctaa catccagtta
    38761 tataacggtg cagttccatc cttattgaag acaaaacctg atacattttt actactatca
    38821 gttaattttg gtgccatttc tgtcaattct tcccaagtag taggtggttg ttcagtatct
    38881 aatccagctt gtttaaacaa atcattattc caatacatat acatgccttg tacctgcatg
    38941 gggacaaaat actgtttacc ttctacttca cctaattcaa tagccgtttc tttaaaatca
    39001 gatttatcta ctccatcata ttcccagaaa tcgtctaatg gttgtaccgc tccgttttct
    39061 acatactgtg caaaatctgg ataatttaat gcaataaagt caggtgcttt tttagaagaa
    39121 atcgctgtag gaagtttttc attcaaattg gcccaagtca tgatatccat ttcaattttg
    39181 atgtttttat catttgtttt attaaattca ttaacgattt cttgcaatat ttcaccatca
    39241 gatgcagtaa acccattcca aaaagtcaaa gtcacttctt tatcagaatc agattctgct
    39301 gaacttccgc caccgcaagc tcctaaaata cctgttgcag ctaccaacaa agagccaatt
    39361 aaccattttt tacctttcat tttttgttcc tccttcatct gataaacgac atctgaccac
    39421 attccaagat agcggtttca ataaacaatt gattttccca tcttcagctt ttacatttgt
    39481 tgaatgactt ggttttactt gttcactttt aggaagatta gttgcttttg tatcaaatcc
    39541 actcatttca gaaaaatcaa tcactccctc taatgataat tcagacaagt gaacagttag
    39601 attcatttct tcttctccac ggttaactgc aaatatgaca agttctttgt catttattac
    39661 ggctatactt tctaaatacg gcacttcttc aaaatcttcc gtcgcatagt ttgctgaacg
    39721 aatttgtggg cttaacacct ctccttgtcc atacacagca gcttgcataa atggataata
    39781 gatcgtctgt ctccaagctt ctccgtttgt ttctgtcctg attggtgcaa taacgtttac
    39841 caattgagca agacaagcaa tctttactct atctgcatgt ttcaataaag tgattaatag
    39901 acagcctaat agtaatgcat cttcaaaatt atagttatct tctagtaaag gaggagcaat
    39961 ctgccaaggc gctgcttgct catcttgttc cgctgaatga taccaaatat tccattcatc
    40021 aaaggacagg ttgatctgct tcttactatg tttcttcgcc ttgactgtat cgcacatcgc
    40081 tgtcacttca gaaatgaacc gatccatgtc taaggaacgt gcaagataat gagaaagatc
    40141 atttttttgg ttgccataat attgatgcag agacaaataa tctatttgat cgtacgcttg
    40201 atcaagaact gttaactccc aatcaccaaa tgtaggcatt tgccgattcg aacttccgca
    40261 taaaaccacc tcaattgaat catctacgag tttcatcgcc ttagccgttt cctctgctaa
    40321 ccgtccatat tcttccgctg ttttatgtcc aatctgccaa ggaccgtcca tttcattccc
    40381 taaacaccat gtcttaattc caaaagggct ctcttgacca ttcgaacgcc ttaaatcact
    40441 ccaataagtt cctttaggaa aattacaata ttcgactaaa ttacgagctg catctactcc
    40501 acgagtaccc agattgacag ccatattgat ttcggccccc acatgctgac accagttata
    40561 aaattcatga atcccaactt cattcgtttc aattgtccgc caagctaaat ccaaccttct
    40621 aggtctattt gctatgggcc caatactgtc ttcccaacga aatcctgaca caaaatttcc
    40681 accaggatat ctaatcatgg gaatgttcaa ttcttttacc aagtgaatga cgtcttggcg
    40741 aaatccactt ttattagctg atggatgatc tggctgataa atcccttcat atactgctcg
    40801 tcccatatgt tcaataaatg aactgtacaa ccgcggatca actttgccta cacgcttgac
    40861 actactaatc aacattgtgg cttccataac tgacctcctt taatttatac atgaataata
    40921 cacctcgttg aaagcgttgt caataatata aatgttaaac ttacttattt tttatcgatt
    40981 ttaattaacc aaaatattaa taatgattaa aacaaataat ttaatataac ttttattaac
    41041 aaatatgtta atatataaga aaaacctttt aagaggtgat atatatgcaa ctacaaataa
    41101 acgaagaatc cttaccggta tatgaagcat tagctagtaa aacaaggatc aagatcatcc
    41161 agctactttc caaaaaaaag atgaatgtca aagatttggc aaaagaactt ggagtgagca
    41221 gtgctatcac gacgatgcac gtgaaaaagc tagaggaagc aaacatcatc aaaacagaaa
    41281 aagtaggaca acaaaaaatt tcgagccttc gtgtcgataa aatcgatatt agttttccag
    41341 aaaaaatatt caatgctttt gatacgaaag aaacatcgat acctattggt cactatacaa
    41401 attatgcaat tgaaccaaca tgcggtttag ctacgatcca tgattttatc gggaaagtgg
    41461 atgaaccacg ctattttatg gatcctcgaa ggatggatgc ccgcattctc tggtttacca
    41521 gcggatttgt cgagtatcag gcacctaatt ttttaaatac agaggataca ttggagatgt
    41581 tggaagtttc tgtggaaatt tcttctgaat ttcctttttc aaatgacaat tggccttcag
    41641 atatcacttt cagcctaaat ggtgtggagc taggaacatg gacgagccct ggagattttg
    41701 ctgatatccg cggtaaatat acgcctgatt ggtatccaga taatcttaat caatacggct
    41761 tgctgaagac gatccgaatt accaaacact tgacgaatat gaatggagaa cccttgtcaa
    41821 acatcacgat caacgacatc cctaaagagc aagacacttg gcatttgcga atcgaagtga
    41881 aagacgatgc caaacatgtg gggggctgta ctttatttgg taaaggattc ggtaattacg
    41941 atcaggatat caaattaaaa gtttactaca gctgatattt ttcttttcta ttttataaaa
    42001 caaaaacagc caatccctat gaagggacgg ctgtttttgc tttattgtta tttccagaaa
    42061 tcatccaaaa cggaaattgg caaatgtcgt ttatgttgtg tcttgttcca ccatgcttcg
    42121 attttttctt gtgcttgagc gggaacttct tttccttcta gataatcatc aatttcatta
    42181 tatgtgacac ctagtgcgac ttcatctgca atcattggtt tcccatcttc aagatctgca
    42241 gtcggaattt ttgtgtataa tttttccggt gcattcaatg cttgaagcaa ttgtttccct
    42301 tgtcgtttgt ccaaacggaa taatggcaaa atgtcggctc caccatcacc aaatttcgtg
    42361 aagaatccag taatgttttc tgcagcatga tctgtcccta atacggctcc tgctctttct
    42421 ccagctacgg catattgcgt aatcatacgt tgacgtgctt tgatatttcc tttgttaaaa
    42481 tcgctgattc ccacacctgc ttcgcttaat acttgtactt gtgcatcaac agctggtttg
    42541 atatttactc gcagactaac atcgggctgg ataaagtcaa gagcagcttt tgcatcttct
    42601 tcatctgctt gttcaccata aggaagacga acagcgataa attgatagtt ttcatctttt
    42661 gtttcttcac gcatttcttc catcgttagt tgcgccaaac ggcctgctaa agtagaatct
    42721 tggccgccgc tgatacctag tacaaaagtt ttaagaaacg gatatttttt caaatatgct
    42781 ttcataaagt caatactttt acgtatttct tcttttggat caattgttgg tttgacacct
    42841 aattcattga taatttctgt ctgcaggctc atttattctc ctcctatgct tctgtatgaa
    42901 gttctgctac gctttttttc attcgttcca tgatagccat tttatggttc cagcattcag
    42961 tagacagatc gactgggtat ttttgcggat tcaagtctcg tttatactct tcccatagtg
    43021 aatctagatt ttcttttgta tattctttga tttcgtttag tgcaggtaat tcgtaaactc
    43081 tttttccttc gataaagata tcttgtaaaa ctgggcgagc tgtaaagtct cgaacagttt
    43141 tattgataaa cgtatgcact ggatggaaca tgaagatagc ttcttcttct cgagggtctt
    43201 catcccataa tgtcacgtag tctccttcag atttcccatc aaaatttcga gtgatgcgcc
    43261 acacttgttt tttccctgga gtagttactt tttctgcatt gcttgataac ttgatcgtat
    43321 ccatcatttt tccttcatca tcttcgatcg atactagctt gaatactgca ccaagggctg
    43381 gctgatcata ggctgtgatc aattttgtcc caacacccca tacatcaatt ttagcttttt
    43441 gcatctttaa attcaaaatc gttgcttcat ccaagtcatt cgaagcatag atttttgctt
    43501 ccgtaaatcc ggctgcatct aattgttccc gaacacgctt agatatatag gccatatctc
    43561 cactgtcgat gcgtacgcct tggaagttga ttttgtcacc taattctttc gccacgcgaa
    43621 tcgcacttgg cacacctgat ttcaacgtat cataagtgtc gactaagaac acgcagtctt
    43681 tatgggtttt agcgtaggcc ataaatgctt cataatcatt tccataagat tggactaacg
    43741 aatgagcatg ggtcccgcta gctggtatcc caaatatctt cccagcacgt acattgcttg
    43801 ttgcatctgc tccgccgata tatgccgctc tagttcccca gactgctgca tccagttctt
    43861 gtgcccgtct agttccaaat tccaatagtg gatcttctcc gatgacagat ttgatacgag
    43921 ctgcttttgt cgcgatcaac gtttggaaat tgaccatatt caacagtgct gtttctacta
    43981 attggcagtg cgctaaaggc ccttccactt ggatcaatgg ttcatttgca aaaactagtt
    44041 ctccttcacg agcagaacga actgttgctt taaattcaaa attttgtaaa tactccaaaa
    44101 aaccttcagg atagacttct aatccacgca agtaagcaat atcggaatca ttgaacgtca
    44161 gattctctaa ataattgact aaccgttcca atcctgcaaa aaccgcgtat ccgtggttaa
    44221 aaggcatttc tcgaaagtaa cattcaaaaa cagcatgtaa atcagctcga cctaattccc
    44281 agtatgtctg catcatattg atttgatata gatccgtatg cagcgtcaaa ctgtcgtctg
    44341 ggtaagtatt attcatcttg tattactcct cttggcaagt tttcatttcc tacccattat
    44401 aacaaaaaaa attaatagga aaagaaatct tccatttttt ctgaaaaagc acatgtttta
    44461 cggatatttc ttgctaaaaa tgaactccat ctgctaaaac tatcctttct tattggtatt
    44521 taacctaaac gagaaagaat acttatttta ttcaatgtat ccgagacacg aagaaattag
    44581 cgttttctat ttttcttact tgataaaata agtagatttt cctactacaa tcgtagccgt
    44641 taagataccg atgattgaac aaatataacc aaatgtctct acaacataat caatggcaaa
    44701 agtttttgaa gcaataatac gtctttcctt ttttgcttct tatccccaaa gaaacggata
    44761 taacttatta tgtattgaat ttttttggaa aggcgaatta tgacaagata taccttgcgt
    44821 tgaaaaaact cgcggaaaaa atatcacacg tttttaaaaa gatacaaagt aagaaagcag
    44881 ctgtcaatag aatggaaaca aaaatggcga gacatcaatc agtctcgcct tgttttttat
    44941 tgtatacatt agatatggag caggttacca taaagatgat tattagtcgt tattaaatag
    45001 aatccttcgt atttttttgt tctatcacta caatatcttt atttggacgt ttgaattgta
    45061 ttccggcacg ttctagctcc tgtttcactc ctacatggac tttgacatct tctcgtgtca
    45121 tttttaaaac gtgatgaatc gcatagtcga tttcttgcct tgtgattttt ttcttcgtat
    45181 tgatcatcac gacttgcttt ttatcatatg tgtctaccaa tagcagttgt gttcgatcta
    45241 acgaaaataa tttgtaataa ttaatagccg tattcccaaa aaagaattcc actactttag
    45301 gataaaatgt cttaatattt aaattactat tcacaggtgt ttcgattagc ttcatctcat
    45361 tcctcttttc tatatagtcg atttagatcc aatcttaagt tatgttacca tctttcctag
    45421 cattaaggaa tcggttacaa ttgaaccttt aaagacaaaa ggatttacct tttatcactt
    45481 aatagtataa cataatttca tgagaaaaaa atacaatttt ttcttgacca tctcgttacg
    45541 taaaggatta tgcttacatt tgtcaggagg aaaaataatg gagtacacaa taaagaaaat
    45601 gtcagagata tcaggagtca gtccgagaac cttgcgcttt tatgatgaga ttggactgct
    45661 aaaaccagct aggatcaatt cttcaggtta tcggatttat ggcaaaaaag aagtcgatcg
    45721 tctgcaacac atcttatttt atcgaacaat ggcattcaag ttggatgata tccaagaggt
    45781 cttagacaat ccatcttttg accaccagaa agctttaatc aagcatcagc aaatgttgct
    45841 ggaaaaacgg gcacaaatcg ataccctctt gacaactgtc caacagacac ttgatatgta
    45901 cgaaggagga agaaaaatga gtgacaaaga aaaatttgaa gggtttaaac aacaaaagtt
    45961 gaaagaaaat gaagaatcct atggacaaga gattcgacaa aaatacggaa aaaaaaaggt
    46021 tacagcatcc aatgaaaaat ggatgaatat ggataaagaa acgtatgaag aaatgcaaac
    46081 tgttgaaaag cagatgttat ttgatctcac tctttactta aaagaaccag aagatgaaag
    46141 cttagcagac cgtatcttcc aagctcataa gaagtggtta tcttacagct ggcctgaata
    46201 tcagccaaaa gcgcataaag gactaggaat gatgtacgaa gccgatgaac ggttcactgc
    46261 atattatgac gagcgaagtg gtcatggtgc agcaaaagct ttaaatgaaa ttatccaaaa
    46321 aaaggcgtaa tcttttacat gatccaacaa aaaagtacac gtaaaatgac ctaataacaa
    46381 aacagcagac acccaagtta gatttttatg ctaacttttg gtgtctgctc cattctttca
    46441 caagtttttt catcctactt taaatatatt catcgttgaa taaacgtata aggtattttc
    46501 actttatcct ttttttctgt aagaaacaat tgaaatgcca tttctccgca agcttccaga
    46561 tggtggtcga tggttgggaa accaagaagc tcgctgatca gcaaattatc gcgtccaatc
    46621 accactggtg tcttatcttg cagatagctt tgcaagatgc ctgctgcaac catatccgaa
    46681 tttgtaaaga caccatcaac tccaagctct ttaaaaaaga agcctgcttg ttttcctttc
    46741 tctgcatcta tacaatccca aaaaacaagt gattcatcaa aagatggaaa aagttgatga
    46801 catagctgca aagtgatttt tgagttataa cttagcctgc cacttcgccc caacgtgatg
    46861 cccaattgct ttataccttg ctgcttcaaa taagtaagac cttctgtaat tgattgttct
    46921 cgatcaataa agacacagct tgcctgtttt cccttgattt cttcacaaaa aactagaggt
    46981 ccatattttt gatatgccaa taaatcatct agtgtattgg cacgagacgt aatgatcaat
    47041 ccatcgaaag ctttagctgc aaattcttca agataccttc gctctttttc tttctgatag
    47101 cccgtcggta aaagtgtcac tttgtaatca taatcaaacg ctgcttcaat gatcccactg
    47161 atcaactgat caaaatacgg atgattggta taaggcagaa tcactccaat gcttttcgtt
    47221 tttccataac ttaactgtct ggcatttgca ttagggatat aatcgacttc tttcatgacc
    47281 gcaagtattt ctttcctttt ttcctcatct acatatggat gtccattgat tacacgtgaa
    47341 atagtagaaa ctgaataacc tgtgagcttt gcgatatctc gaatgtttgc cactgctgct
    47401 tcgccaccta tacaaaaaga ttttcttgta aatagtctac cacagctgga ccgcattcaa
    47461 aaaactgata catttttcct tcatgcgaaa aactgatccg ctgcccgccc caatatatat
    47521 cttttgtcaa attttcgatt tcattcattg gtatttcttt tactatattc ctattcaacc
    47581 cttgaaaact gtacaacgtt aatacggatc ccttgaactc gacaaacgca taaaaataat
    47641 tgttcgttgt gccatctgtt atctctacat aagtattcat tgcaagccct ccttttgata
    47701 ctttgagtat agtgtatgaa acgcgtctca tagcaaggag tttgttttgc caaagaaaag
    47761 ttttattcct ctttcattat taccaaagtc tcttatttta aattgaatac attataatga
    47821 tactgtaaat atatctttat tattagtgaa tggatattta cttttaatag ataaaatatt
    47881 ataactatta aaaataacta ttttcattat aattacacac aaaaaagagc gtgagacaaa
    47941 agtaaagaac acttttgtct cacgctctaa acacgtataa acagcggaag cagaagcaac
    48001 tccttcggaa ataagctgaa attcacaaaa atttgaaaag caatttccgt gaatttcttc
    48061 ttatttcttg gagttaaacg cttctgttcc agcctctttt tatctgtctt tcactaatga
    48121 tcagttgtag ataagcaagt tgctttttct tacatcatac cgcccatcaa gacaaatgtt
    48181 tttcacttgt ccacactgga caaaaatccc atcaaatcaa ggaaaagcaa cgttggcaat
    48241 gtttgaattt tttaggctag aacggactag taagagtttt ttgccccttt tttgcccctc
    48301 aaatatcgct ttacaac
//
LOCUS       DBBGRF010000020        45668 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000020 DBBGRF010000000
VERSION     DBBGRF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 45668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.020"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            4..243
                     /locus_tag="ACIZD4_001226"
     CDS             4..243
                     /locus_tag="ACIZD4_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990174.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            310..519
                     /locus_tag="ACIZD4_001227"
     CDS             310..519
                     /locus_tag="ACIZD4_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990175.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            579..1250
                     /locus_tag="ACIZD4_001228"
     CDS             579..1250
                     /locus_tag="ACIZD4_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HGC5990176.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1303..3279
                     /locus_tag="ACIZD4_001229"
     CDS             1303..3279
                     /locus_tag="ACIZD4_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC5990177.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            3292..4047
                     /locus_tag="ACIZD4_001230"
     CDS             3292..4047
                     /locus_tag="ACIZD4_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC5990178.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            4044..4868
                     /locus_tag="ACIZD4_001231"
     CDS             4044..4868
                     /locus_tag="ACIZD4_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HGC5990179.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            4878..5126
                     /locus_tag="ACIZD4_001232"
     CDS             4878..5126
                     /locus_tag="ACIZD4_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990180.1"
                     /translation="MKIIRILVFNLSFLAATILCCGLIFSQLSIYPRYQRLFIHFLNI
                     QCASMPLEVIKKLLINPIFMVSLVLLTGLVTWVLGKKE"
     gene            5169..7268
                     /locus_tag="ACIZD4_001233"
     CDS             5169..7268
                     /locus_tag="ACIZD4_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HGC5990181.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLANA
                     ANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQDPVED
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(7306..9363)
                     /locus_tag="ACIZD4_001234"
     CDS             complement(7306..9363)
                     /locus_tag="ACIZD4_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HGC5990182.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(9477..9689)
                     /locus_tag="ACIZD4_001235"
     CDS             complement(9477..9689)
                     /locus_tag="ACIZD4_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990183.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            9876..10343
                     /locus_tag="ACIZD4_001236"
     CDS             9876..10343
                     /locus_tag="ACIZD4_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990184.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            10340..10582
                     /locus_tag="ACIZD4_001237"
     CDS             10340..10582
                     /locus_tag="ACIZD4_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HGC5990185.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            10600..10902
                     /locus_tag="ACIZD4_001238"
     CDS             10600..10902
                     /locus_tag="ACIZD4_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990186.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            10974..13028
                     /locus_tag="ACIZD4_001239"
     CDS             10974..13028
                     /locus_tag="ACIZD4_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990187.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQSYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            13028..15640
                     /locus_tag="ACIZD4_001240"
     CDS             13028..15640
                     /locus_tag="ACIZD4_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HGC5990188.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFSEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            15637..18168
                     /locus_tag="ACIZD4_001241"
     CDS             15637..18168
                     /locus_tag="ACIZD4_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HGC5990189.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PEQAKGMAGNDKSGLSDIQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEDKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            18220..18552
                     /locus_tag="ACIZD4_001242"
     CDS             18220..18552
                     /locus_tag="ACIZD4_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990190.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            18553..19146
                     /locus_tag="ACIZD4_001243"
     CDS             18553..19146
                     /locus_tag="ACIZD4_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990191.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            19309..21003
                     /locus_tag="ACIZD4_001244"
     CDS             19309..21003
                     /locus_tag="ACIZD4_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HGC5990192.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEIVKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            21691..23568
                     /gene="ltrA"
                     /locus_tag="ACIZD4_001245"
     CDS             21691..23568
                     /gene="ltrA"
                     /locus_tag="ACIZD4_001245"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGC5990193.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            23699..24076
                     /locus_tag="ACIZD4_001246"
                     /pseudo
     CDS             23699..24076
                     /locus_tag="ACIZD4_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            24076..25281
                     /locus_tag="ACIZD4_001247"
     CDS             24076..25281
                     /locus_tag="ACIZD4_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC5990194.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            25297..25941
                     /locus_tag="ACIZD4_001248"
     CDS             25297..25941
                     /locus_tag="ACIZD4_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990195.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            25952..26758
                     /locus_tag="ACIZD4_001249"
     CDS             25952..26758
                     /locus_tag="ACIZD4_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990196.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIFYIH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            26780..27010
                     /locus_tag="ACIZD4_001250"
     CDS             26780..27010
                     /locus_tag="ACIZD4_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990197.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            27556..27831
                     /locus_tag="ACIZD4_001251"
     CDS             27556..27831
                     /locus_tag="ACIZD4_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990198.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            27873..28295
                     /locus_tag="ACIZD4_001252"
     CDS             27873..28295
                     /locus_tag="ACIZD4_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990199.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            28314..29906
                     /gene="mobP2"
                     /locus_tag="ACIZD4_001253"
     CDS             28314..29906
                     /gene="mobP2"
                     /locus_tag="ACIZD4_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HGC5990200.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            29918..30253
                     /locus_tag="ACIZD4_001254"
     CDS             29918..30253
                     /locus_tag="ACIZD4_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990201.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            30400..30594
                     /locus_tag="ACIZD4_001255"
     CDS             30400..30594
                     /locus_tag="ACIZD4_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990202.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            30626..32998
                     /locus_tag="ACIZD4_001256"
     CDS             30626..32998
                     /locus_tag="ACIZD4_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HGC5990203.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            33059..34519
                     /locus_tag="ACIZD4_001257"
     CDS             33059..34519
                     /locus_tag="ACIZD4_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HGC5990204.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            34530..36734
                     /gene="topB"
                     /locus_tag="ACIZD4_001258"
     CDS             34530..36734
                     /gene="topB"
                     /locus_tag="ACIZD4_001258"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HGC5990205.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            36750..36899
                     /locus_tag="ACIZD4_001259"
     CDS             36750..36899
                     /locus_tag="ACIZD4_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990206.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            36973..37566
                     /locus_tag="ACIZD4_001260"
     CDS             36973..37566
                     /locus_tag="ACIZD4_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HGC5990207.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            37582..38481
                     /locus_tag="ACIZD4_001261"
     CDS             37582..38481
                     /locus_tag="ACIZD4_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HGC5990208.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            38484..38969
                     /gene="ssb"
                     /locus_tag="ACIZD4_001262"
     CDS             38484..38969
                     /gene="ssb"
                     /locus_tag="ACIZD4_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGC5990209.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            39335..39595
                     /locus_tag="ACIZD4_001263"
     CDS             39335..39595
                     /locus_tag="ACIZD4_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990210.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            40036..40242
                     /locus_tag="ACIZD4_001264"
     CDS             40036..40242
                     /locus_tag="ACIZD4_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HGC5990211.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            40242..40493
                     /locus_tag="ACIZD4_001265"
     CDS             40242..40493
                     /locus_tag="ACIZD4_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990212.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            40508..40945
                     /locus_tag="ACIZD4_001266"
     CDS             40508..40945
                     /locus_tag="ACIZD4_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990213.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            40938..41645
                     /locus_tag="ACIZD4_001267"
     CDS             40938..41645
                     /locus_tag="ACIZD4_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990214.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            41810..42010
                     /locus_tag="ACIZD4_001268"
     CDS             41810..42010
                     /locus_tag="ACIZD4_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990215.1"
                     /translation="MNKIIPLLFVLFVGEILMRHAAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            42026..42205
                     /locus_tag="ACIZD4_001269"
     CDS             42026..42205
                     /locus_tag="ACIZD4_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990216.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            42546..42809
                     /locus_tag="ACIZD4_001270"
     CDS             42546..42809
                     /locus_tag="ACIZD4_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HGC5990217.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            42803..43153
                     /locus_tag="ACIZD4_001271"
     CDS             42803..43153
                     /locus_tag="ACIZD4_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC5990218.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(43177..43791)
                     /locus_tag="ACIZD4_001272"
     CDS             complement(43177..43791)
                     /locus_tag="ACIZD4_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5990219.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            44105..44527
                     /locus_tag="ACIZD4_001273"
     CDS             44105..44527
                     /locus_tag="ACIZD4_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990220.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            44537..44740
                     /locus_tag="ACIZD4_001274"
     CDS             44537..44740
                     /locus_tag="ACIZD4_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990221.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            44951..45535
                     /locus_tag="ACIZD4_001275"
     CDS             44951..45535
                     /locus_tag="ACIZD4_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5990222.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT        16743 a         7205 c         9260 g        12460 t
ORIGIN      
        1 tagatggcgc gaccagtttt agaggcgatg gatatggata ctttgacaaa aggaaggtat
       61 gtacagctgt tagctcgtgg ttattcacct aaagaagtat tcaaagcctt atctaaagga
      121 acagatatgg aaaaagaaag attgcgaaaa gaattcgatt attggagaac ccataatgga
      181 atcaaggatt tgaaaccagc acggccagta attaaacgaa agaaaaagat aacccaagac
      241 tgaagtgtag agcgtatgtg atcataggct tttttatttt tgcaaaaaac aaggaaggta
      301 ggaaaactca tgaattatga agaaatcgaa aacagaaaaa aagtgtcgaa agaaatggaa
      361 gaaaagttac taaaaacgat gaagcaaaaa caccttaaaa gattatctgt cgcgcaatat
      421 atcaatgata tgcagttaac aggaaaagag aaagcttgtt tgttaggttc aatgaaaaac
      481 tttgaacagt tgagacgaac ttatagaatt catttttaaa actttttcta tggaaatgag
      541 aaaaagtttt tttgttttgt ctgaaaggag gcagatggat gaaaaaatgg ttatttggtt
      601 ttttaggagt cactttaatc gtcttttgca gtgtgtttgg ctatgttagc taccaaaaac
      661 atgaaggaga ggtgtttaag caaaatatag aaaaaaagat gcccgtagat caaatcaatg
      721 cacatgcaaa gagttataag gaggatgcaa cgaacgtcaa taatgatatg tctttggggc
      781 aaatgttgtc catacaaaaa gaagcaatcg aaatgggcgt caataaacaa gtatttgcac
      841 aaattcagat tcctgcactt ggtttagcat tgccaatttt taaaggggca aatcaataca
      901 ctttgagtct tggagcggct acttattttt atgaagatgc cgaaatgggc aaaggaaact
      961 atgtcctagc aggtcataac atggaaatgc caggtgtttt attttctgat attcaaaagt
     1021 tgtcattagg ggaggtgatg gacttagtta gtaacgatgg cgtctatcgt tacaaggtaa
     1081 cgcgtaaatt tatcgtacct gggtacttta aattaatcga tggcgttcct gaagagaact
     1141 ctttcttgtc tttgccaaag aaaggagaga aacccttatt aacgttgttt acttgtgttt
     1201 atacgtcaca aggaaaagaa agatacgtgg tacagggaga gctacaataa caaggtttta
     1261 atcaacgcga gtcgttgaaa tatgaaatga ggagagtaaa aaatggcaat aaatcggtat
     1321 gtaaaaaaag ctggaatgct tgttggaatg ttaggaatca ttgcaggctg ctttcagggg
     1381 tatcaagtac atgcagaaga tgtcacgcaa aaaacaccac cagagaaggt caatatcacg
     1441 gttcataaat taatgtacga tcaaggaacg caattgaatg ttgatattga cgggatcaaa
     1501 aacgatggtt atacgcacga tcaatatcct acaggtgtaa cgaaatacaa caaggcagat
     1561 tatggtgatg ttgagtttac gttaggaaat attacggatc aagtattacc gagagaagat
     1621 tctgatctaa ccaacgcgaa agtggacgag attgtacaag atgtagaaga caagggatct
     1681 aacagtgagt acgtcaagaa tgcaaccaac aaaattactt cagctgtaga tgaaaatggt
     1741 gagatcactt ttactgatca accagcctat gtcaattcca aagggaatgt atatgtggtt
     1801 tatgaaagta aatccgctgc tggattagtc acacaaaaag caaaaccaat ggttgtgatt
     1861 gcgccaatga cagataaaac aggatcagga tttttaaaaa atattcattt gtatcctaag
     1921 aacattgttt ctaagttgag ttttgaatta acgaaatttg gtgacgatgg cgcagaccaa
     1981 agcaaacaaa cccttttaaa aggggcaaaa tttgagttat acaagggcga acctggaaaa
     2041 ggaacaaaat tgggtgatct tgtatcggat gatcaaggaa agctgactgc gactgatttg
     2101 acgttaggaa aatactattt tgtggaagtt ccttcggaag ttgtagtggg atcagatcaa
     2161 gaaccaacag cagatcaata tttattaggc gcagacgctc gcaacgatgc gcacaataaa
     2221 ttaacctttg aaattacgaa tgatggcgtg acaagtgact taaaagcttc atacgtaaac
     2281 tataaagcac cagtgatcga taaaacagta acaaatggaa caggacaaga acattctttc
     2341 caaattggtg acgcagtaaa ttatcaagga acgattcata ttccaacaga cattgcaggt
     2401 ggcgcagacg gtatcacagt aaacggtgtg aaaagcgaaa cttctcctta cagtgtattt
     2461 aaatggggag atacagcagg taaaggactt tcttatgttg ctgaaaaagc agatattaaa
     2521 gtaacaaata atgatggttc agtcgtatta aaagaaaata ctgactataa aatcgaaaat
     2581 tctgatagtg gttttgtgat cgattttatc gtaaataatg gacaagtaag tgatacagtt
     2641 gcgaatttac atggtcaaga tctaaaaatg acttataaca tgtttgtgaa tgatagtgct
     2701 gaaatcgcaa atccattaac aaatagcgtg gatttcgttt ataacaataa tccatttaat
     2761 caggaagaac accacgaaaa aacgaaagct gacgttgtga cttatggcgc aaaattctta
     2821 aaagtcgata gcggcctatt tggaacaggt atcaaagcaa caccgcttga aggcgcagaa
     2881 tttgcagcta agaatgcaga aggtaagtac tacggtggac ttactgatac agataaagat
     2941 ggtgtcaaag aagcagtttg ggtagacgat gtagcaaatg cagcaatcct aaaatcagat
     3001 aaagagggtc attttgaaat cactggttta actgaaggag attactcact ggaagaaaca
     3061 aaagctcctg aaaactatca aaaattaaca aaagagatct ctttcaaagt agacaaagat
     3121 tcatacaaag aagaaaaccg aatcacgatc aaaaataatc aaaaagcttc cgtaccaatg
     3181 actggtagca acggtttcca atcttacgta ttgatctctt gcttgttgct aggagcaggg
     3241 ggactttctg cagttgttta ctttaagaag aaagcctaga aggatcagct aatgattatt
     3301 cgtaagcccc caaaaagaag agtcatgcac aaactgatga tatttttttg gttgctgtcg
     3361 gcagtagcag tctatttaat tccagttgtg gaaacaaatg tagcgaaatt tcaacaacag
     3421 caaagaattt tagccattga aaatcttgaa aaaacagatt cttctttgga tgttgcgaaa
     3481 atagagttag gcgatcctgt tggtgttctt acaattccaa gtatttcttt aaaactacca
     3541 atttatgacg gaacttccga caaaatttta gagaatggtg tagggattac ggaaggaact
     3601 ggcgatatta caggaggaaa cggtaaaaat cctttaatcg cggggcacag tggactttat
     3661 aaagataatc ttttcgatga tttgccttca gtaaaaaaag ggcaaaaatt ctttattaag
     3721 gtaaatgaag aacaacatgc ctatcaaatt tatcgaattg aagaagttaa agcagaagaa
     3781 ttacaaaaaa attatttaga ttatcttatg cctgaaaaag accaagatag gatcacgtta
     3841 atgacatgca caccaaaagg tgtcaactca caccgctttt tagtgtatgg tgaacgagtt
     3901 tccttcagta aagaagattt aaaactacag aaaaaagcaa aaaataggaa atcaatttca
     3961 ttggattggc gattagcact gctattcgct tttttttgcg ttcctattat ttttatttat
     4021 aaaaaaataa ggaggagatc ggaatgaata agagaaaatg gctgtttgtt tgtgtagcag
     4081 ctctcttttc tactgtagct tattcgcaac tgtctttcgc tgacagcagt gatagtagta
     4141 ccactcaaac aatagataat tcaattactg caccaagcga aacggacagt tcggagaata
     4201 ctacagaaga aacggcagat tcaaatataa gctttactga atcaacgaat ccaacgtcag
     4261 aaagttcttc agagacttca gaaaagccgc aagacgtaga agatacgcaa gtgatcaagc
     4321 aagccattca tattcaaaaa attatttctt cgaatcaaat caacaatcaa ggcagtcaag
     4381 tagcccagca agaaggtatc aatggcgcga agtttattgt ctacgatatc acgaatatct
     4441 tagaagaaat gtcacaagat gataatgaga aaaatcaatc tgtagaaata attgagtcaa
     4501 aattgaaaga tcgagcaaaa aaactttcat acgaccagtt gaaaaaagtg gctgaaggag
     4561 aaaccaaaac gattgatgat caggaaggcg tgattgaatt ttccattgaa gtacctgcaa
     4621 acaaaaaaca agcatactat atcgttaatg aatcaagccc tgaaaacatt tcaaacagtg
     4681 aagatattgt tttattgaca cctgtttcaa atgaaaaagg tgaatttttg acggatgttt
     4741 ggttataccc taaatcagag aaatcagagc cgaaagaaga aattaaaaaa gttgtgtcaa
     4801 ctggtgtaaa gaagaacttt tttgaaaatt gttgggaatt ttttgctcaa ttattttttg
     4861 ataattagga tgaaatgatg aaaataataa gaatattagt ttttaatcta tcctttttag
     4921 ccgcaacaat attgtgttgc ggtttaattt tttctcaatt atcaatttat ccaagatatc
     4981 aacgattgtt cattcatttt ctaaacattc aatgtgcttc catgccatta gaggtgatta
     5041 aaaagctctt gatcaatcca atttttatgg ttagtttggt tcttcttaca ggattggtaa
     5101 cgtgggtatt aggaaaaaaa gaatgaaaag cttacgatcg tttaaaaaaa tattagatgg
     5161 agggcattat ggaaaataaa attcattgca ctacgggaag agtaattact ttagtgttgt
     5221 ttttgttcct tcttcttttt gcgaggggaa ctgcagtcca ggccttagaa aaagttgatc
     5281 cgagtcaaat caaagaaaat aataatctgg tgctttatca tgatagtgat tcattgagaa
     5341 atatcgaagt aactgggatc aatggattta agatactaga tgagtattca actaaaaaac
     5401 aaaaagtact tgcttggcca aaagtcaaag atttgaaaag tacgtcaaaa atcgttgccc
     5461 attatcaaaa agtaggtact tatctaggaa aagaaattga ttgtgacgtg actttttcta
     5521 attttgtagc gcacgctggg gttaaccaag acggattagc taaaacaatt aatggcaaaa
     5581 agtattataa ttatttgctc tttgataaaa atatttatcg aggatttttc atgcagtcaa
     5641 tcaatgtcat gaatgcaaaa ctagaattta agtatgcagg aacaaaaaca aaagtagctt
     5701 tgagtgaacc acagccagaa attcaatcaa aaatgagatc gatgagagca gctggtattg
     5761 atttaaacga tacatttcta tccatttaca gtttaaatgg acagtatcag caacgtgtgt
     5821 cttggtataa tgacaataat gaatctgtcg gtgaacgtaa tattgatatg agagaatttg
     5881 ttgggtatga aaaaatgggt agcttacctt attttgtcac aacagataca gcatgtgcag
     5941 aatacaaagc tcctgcgtta tcaacaaaca atttaacttc aaaagtagtg ggaggacgtg
     6001 cagaaaaggc ttatagctcg aatgatcatt tcaccgatgt tgtaggagct gatacttatc
     6061 acagaagtgg tgtaacgtat acgcttcaag gcgcttcccc aacattcatg attggcgcaa
     6121 atacgaatag tatgatgttt agctttgata ctgcattgct atggacacca caaccatcga
     6181 agcctacaaa agaagtgttt aacaaagcta atactgaaga ggcagcacac aatattgaca
     6241 aaaaagtgat tccacaagga tcagatgttt actatcatat tcaccaaaag tttgatgcat
     6301 taacagtcaa cacaatgaac aaatacaaat catttaaaat cactgatacc tttgacagca
     6361 aaaattttga tatggtatcg gatgggaaaa actatgatgg cgcattgtgg tatgttgaag
     6421 cgaatggtac ttggaaaaaa gctgatacag gaggaaagtt aactgtatca ggtaatacag
     6481 tcacttatac tgcttctgac agctttttag ctaacgctgc aaattacggt agggattata
     6541 ttttgcagct ccatatgaga gcaaaaaatg atgcaaaagg aattgcacca aatgtggcta
     6601 ctgtaacgtt taacaatgat ccgaacaaag gaacacaaaa aacaaataca gtagaaaact
     6661 atttctctct taaaccaaat aaaaaagtgg aacaagatgg gaaagatgtt gatggtcgaa
     6721 atgatggtaa aaaaggaacg cctacagctc ctttaaatgc aggatctgaa gtacaatatc
     6781 tagtcacaca aaaatggcat acaaaaggtg tagacattgc ctcagatcat tacaagcaat
     6841 ttagtattca agatccagtg gaagatcgtt tgacgtataa agaaggttct gcgcgagtga
     6901 tagatatgag tacaggaaaa gatattactt cagaaggtac actaacctat gatagcaatt
     6961 caagaacgct gaagtgggaa gcttccgctg atttcttaag taaaaatctt ttagatggac
     7021 gagaaattca gctgatattt acagctaaaa ctcctttgaa tgaagaattg gatatcgaca
     7081 accaagcaaa agtttcagta gaaagtattg agaaagcaac taatgtagta acgattgggg
     7141 taaaacctaa cttacctcag atcattgtgc caaaaactgg atcgaatcat ttagtgctaa
     7201 ctgttattgg aagtatatta tttcttactt tagcatcatt gggctatgta gttttaaaac
     7261 tcaaataaat ataaaaacaa ggctgagaat cagccttgtt ttcttttatt tgaagattgg
     7321 attcgcacta ataaatacat tatctacgcc aattctacca gcagagtcaa ctacaaaatt
     7381 atgacctaat ccgagaatac tttggttatt ataaagtaaa tttgcattat gggcagggct
     7441 atttttccat cctaccatgg catcgatagc accatcgtct gataaaaggt catcaatata
     7501 cagcccagtt tgacttatgt tttctccctt agcaccgtag cagcctaagc tttccaataa
     7561 atcttggaaa gtaccaccac cagggcgata gtgactgaag ctgacttgta attctttagc
     7621 tcgaatatct gcagcctgtt gaacaatatc attgaattgc attggggcaa caccattttg
     7681 ttggcgataa tcatttaacc aagcaagttc tttttgacgc ataaagttac gtaattcgtc
     7741 taatgaaatc tttttatatt tgaatgtgat tgttttattt tgatcgacgt tattaatgga
     7801 tcgttggccg tttttatcca cggtaacggt aggatcgtca tttctgcaca agaaataatt
     7861 ttgatcagtc atgtttttcc aaggagtagc aaagctatcc ccttcgtata ctgtttttga
     7921 ttcactagag agaacagcgt tggtatcagc atttacatga ttaacagtca cattaaattt
     7981 acgagtgtag ttgaaaatat aattttgact ttcagtcaca ttgtttaagg ttactgaatt
     8041 tgttggttct acccgatcgt ctaaaacata tccttgaata gaaggagcag ttaaagtgac
     8101 actgtcaccg tgagtgacat tgactatctg ttctttcaaa atattaactc gtccttcgtt
     8161 tttgtagttg ttattgcaca acaaattgat ttgatgcact tgattataat tgaatgtgat
     8221 tgttgtatta cctgtgattg ttttgctttg agtatcatta ccaatcactt tgtagctaaa
     8281 attatcttta gcgccttcgc tatatttaaa tgcttttgcc ttagcagtgt aagtagaacc
     8341 agaagttact tttgcttgat ctgtagcaat cacttgacct gtttgattgt caatatggtt
     8401 aatagtaacc gtatattctt ttggtgtttc aggtttgtgt tgcaaccctt taaatgcagc
     8461 atcaagacta tttttagcat tgtttacttg tgtttgagaa accttagaat cgtctagtac
     8521 ttttttagca ttggataaag cagtctgaaa attattccaa gattcttctg taaaatctcc
     8581 tttagcagtt gattttactc ggttgtataa agcttgtaat tcagctttat tcacagtagg
     8641 aactggtttt ttctttaatc ctttgtaagc agaatctaat ttatttttgg cactatccac
     8701 ttgcttttga gtcgcttttg agtcatttaa cactttctta gcattgttta aagcggtttg
     8761 gaatgcgttc caggtattgt cggtatagtc accttttttc gttcccttaa cgctcgtata
     8821 aagagcttct agagccgatt tattcacttt gggtttagag gtgtcagcgc cataccaacc
     8881 gataccttcg tatttccagc catagtcttt ggttaaccat tgtacttctt tccaacttgc
     8941 agtgtagtga tgtgagccag attttacacc aggaaggaaa aggcggtaga tcggtttatt
     9001 atttttttcg gcagaacgcc aggcaggccc ttcataagtc cagccgtaat ttttagtcaa
     9061 ccatttcact tcatcccaac tagctgtgta atggtgatca cgaagacctt tattgtacaa
     9121 acgatagaca agatggccac cgctagtcgg tgcttcccag gcggggcctt cataatttcc
     9181 ccattttatc tttactagat ggtcacgttc ttttttgcta gaggtgtaaa aatgttcatt
     9241 attatttgga ttgtaaaggc gatacatgac gttagttgaa gcagcgtcaa cagatccagc
     9301 aagactaagt gaggcagcaa atgttccaat agctaaaaca gtttttggat taaataattt
     9361 cattttttca actcctaaat ttaattaaaa atgtttacat gattattata tatcggctaa
     9421 ccgatatagt caataaaaaa taagaaaagc cttatataat tttggctttt cttattttat
     9481 ttgttagttg aagtattaat atcaacgatt tcttcagcca atttatttaa tttcatagca
     9541 tttatgaatc tcatgttgtc tatactagag cgtttgttgg caaggtcact tactgtagtt
     9601 aagggtacgc cagattctat ggatatagaa cgaactgatt taccactatc aaacagcaac
     9661 cattcgattt tctttttatc agcgtacatt tcaatgctcc ttcttgtttt ttctttatta
     9721 tagctctttt ttgtaatgaa tcacaatatc aagagaaaaa ttttctatag aaaggtggat
     9781 ttttatgagt attcgttctc cgtgtatcca aatgaggttt gttgctactt tcgttatttg
     9841 atatactaaa aataaacaac gaaagaagga ataaaatgaa gaaaaagcaa ctatggtttg
     9901 tctctatgtt tgcaatattt tttattattt taagtggatg ttcaagtaat aagaaatcgg
     9961 aagctaaaga agataatagt ttattgcaac caggaactgt ttggaaagaa gaagtaggtg
    10021 gtcttattca taatttaaaa attatagatg atactacctg ggaatattct gaaagtgtat
    10081 ggcatccaga tcctgtacaa ataacagtta agaggcaaaa agactatgaa ggtttagaaa
    10141 gatacaaaat agtagattct gcaggcatta gggaatttat aaacaaacct gattcattat
    10201 ttattgttgt tccctatgag aaggatggcg taaaaaaaat aatttttctt ggatctagca
    10261 aggatgagaa gcgaacgaaa gagaaattaa ttcatgatgg atcagagtta aataaataca
    10321 aattacaaaa gactagtgag tgattgctag tctttttatt tatcctgaag gaggaatcac
    10381 agtggcaaaa gttaaaacac cattcgaaaa agccgcgtct aaaatcttag aacgccgtgg
    10441 tgtttctgaa atacagtgga aaaaagaagt tcttgaaaaa gcacaatttg acctattacg
    10501 aggaaaagat aaggacttag aagaatatat ctatcaacgt gaacgtgaaa aacttgtatt
    10561 cgatgaaatt attaaacatt aaaaggagcg aataatctta tgtttgaatc aattacaatg
    10621 aattttttaa ctcaaccgaa agtagtagct gcagttgata tttttagagc attacaaact
    10681 gccgcaacta gtttgaaaaa taatctgatg atttttgcgg ctgtagctgc cgttgcctcc
    10741 attgctcttg gaggtatttt cttcttcttt gggcgaagag gagctgaaaa cgggaagaca
    10801 cacgtaggtt atgtattgtt gggggtagga gttattttag ctgccgcttc tattgtagtt
    10861 tcaatgttct caatgtttgg acaaacccca caaggactat aaaaaaaaca agtaggagga
    10921 gtaaaaagta cgtggctact ttttactcct ttttttatga aaggagaata ttcatgtttt
    10981 ttacgatttc aggaaatgca aaattggata aagagttaat aagaaaagca acgaagaaag
    11041 tgggaaagcg tacttccttt ttaccgaaaa caattaaata ttctgtcatt gaaacggaag
    11101 aacagctaca tgtgttagga caagtgttag aacaagagaa tcaatcttct gttaaattga
    11161 ctctcacgtt acatgataaa gaaggaaaaa tagaaaaggc tggcacagaa tacgtttttg
    11221 gcccactgga ttatcaaatt tcagaaggtt tttatcctac attgatagat ttaatccgcc
    11281 ttgatgtgtt taaagatacg gatgaaacta tgagtgtgga agagtcttat cgaaacgaaa
    11341 aactgctaca agttttagaa gaagagttag agagcgacca aagaaaagtg aatcaagtga
    11401 gtgaagtcga agtaaatgaa gaagtaccat gggaacgacc aatatttcca aagaaggagt
    11461 caaaagaaaa agagacagtc tatgttgacg aacaagctga tattccgact cagaaatcga
    11521 tatttgagga agagaacgat gtgatgggtc aattggaggt agatcccttt gaagaaacaa
    11581 tggaggatga agagacggcc gaagtagaag ttgatccagt tgaagctaat gaagagtcaa
    11641 catggactga aggggattct caggaatata ttgaaccact tatcagtgaa gaagtagaaa
    11701 aaaacgaaac agagatacaa aaggcaactg tatttgatta tattttggat caatatccgc
    11761 cagagcatga atggatgaaa gaaaaaaaca aattattttt aaatgagctt tattcgaaat
    11821 atcaattacc ccaaagctat caagcatttt tagagagtaa agaagaatta atctcacagg
    11881 gtaaaggcac acttttagaa cagttagagt ctgtccaatc aacaaattgg catgagcttg
    11941 cacaagaaga tttattagcc acctttgaag aacgtcaaca agaaacagat caagaaatta
    12001 atgagtatgc gacggaacag tcgtctaatt gggagaaagt aaaagaggaa ctaaataaag
    12061 aagaacagcg agtgattgaa gaagaagtac aaaaaatcaa agagcggtac gaaaagaaac
    12121 gcgacaatgc ttattccttg tgtgtagaaa agatcaacaa ttttactaag acgaatcaag
    12181 aagcgttatc gaaagaaaaa gaaaacttgt taaaagaacg tattaaagaa cgaaaagaag
    12241 agttctaccg cggtttacgt acagataagc taaagattag caaagaatta aatgaacaac
    12301 tgaataagct atatcaaaca acgactgaag ttcttatgga aaaacacgaa cagatccagc
    12361 aagaattaca agtacaaatt ccaaaatgga aaaaagagta tgaaattcaa caacaagaat
    12421 tgaaagaaca agaagaaaaa caacggcaaa aagaaaaaga gcgtgaacaa ttagaaataa
    12481 gaaaacggga acaggatctt gcggaacaaa aaatggcgat agaaaaacaa cggttagagc
    12541 aagaaaagga aaaagaagca gctgctcgta aggaacgtca agaacaaatg gatacattgc
    12601 gtcaagcaca gttgaattat ctagcacaac ctcaaccagt agctgctgtt caaacgccag
    12661 tgaacaacca agcaaattta actccttcac cccagcgttc ctttaacgga tggatggtgg
    12721 gatgtattgc aagtttaagc ttgcttctag gtggaggaac agtatttgct tttaatcata
    12781 tcaatcaatc ttcacaggct gattctgtag ccacaacggc gtcaatcaag gaagaagccc
    12841 aggaacaagc aagaaaagag tatgaacaac aattagaaga attattgaat cgtaccaatc
    12901 agtcaacaac agagtcaagc atggaaaata gcaaagagag tgatcctagt aaggctaaag
    12961 aaggatcaag cgattcaact gtacactcaa acacttccga aagttcagaa tcaaatgagg
    13021 tgaaataatg cgtattagag aaacaacgag acgaaaagac aaacgattca atttagaaaa
    13081 gaataggtat ctttctcatt tctatcgcta tactccttca ggagaagagc taccagaaaa
    13141 acatgacaaa cgtatttctc aaaagatttt ttatagtggc ttagcttatc ttcctttaaa
    13201 ctatgttgtt acaagaatac cagaagcatt tcatcgattt gagattattc caggaagttt
    13261 acaaggagtg aatatttttc agttacaaga aatgccgcag ttattccatt ttgattcaac
    13321 tggtttttgg aatcctttga ccccaacaac aagtttaggc acacgtttag ttgtttctac
    13381 gatttgtgtt gttccagctg tacttatggg attgaaaatg gacatgtggt ttcgtccgct
    13441 agcagatgga caaaaagggg ataatcgatt aatgacctta aaagaaatcc aacagattta
    13501 tccgcaaata cctgaaacaa aaactacttt tccaggttat ggaggtattc caatcacaca
    13561 ttacaaaaaa tattggtaca ttcaaacaga tactgttaat acgtgtattg ttggtacctc
    13621 tcgatcaggg aaaggtcaga ttgaagtgtt agccaccatt gacaatttat ctcgtgcaga
    13681 aaaacaaagt tcaatggtcg ttaatgatcc aaaaacagaa ttatatgttg gtagtaaaga
    13741 tgaactagaa gctagagggt atgatgtata tgcctttaat atcaccgatc cactgcaatc
    13801 aatgagtgat aatccattgg cactcatcgt gaaatactgg aaacgaggag acatagatac
    13861 tgcaacacag ttaaccaata ctttcacaaa tacgatttat tatgatgcca acgcttcaga
    13921 taacaaatac tttaacgaaa acgcgcagaa agctgtcaat gcgcttattt ttgcgttgtt
    13981 agaacaagct gatcaaacag gagattactc caaattgaca ccgaataatc tcgttgagct
    14041 tctttctgag attggcggtt ttaattatta tccagatcca gacaatgaat tcaaacagtt
    14101 gaatgcctta gatgaattta tgaatcagtt gccacctgga aacattgcaa aaaaacaata
    14161 tggggcaacg aaaattggat ctgataaagc gaagggaaat attttatcaa cggcaatcac
    14221 gggattgaat ccatttactc taacgaaaat tgcaaagatg acttctcaat caacgattga
    14281 ttataaatcg gttgggtttc caaaatactt agatttgaaa ttacatgaaa gtcttttaaa
    14341 tcaacgagtc gtagtagaat tttatcataa gggaaagaaa tttcatgaag aacgtgtcaa
    14401 agtaggctat aaaggattta gtgaaatcaa ttttgattgt catttagttg caggtgatca
    14461 agtttgttta aaatacgatc atcaaggaaa agaatatgtg gcttggtatg aattttctca
    14521 aagagtattg aaagacgaag agggtaatat cgtttatcgg aaaaaacgag gagaaaccca
    14581 tttgccagaa ttagaaaaag aagccgttct aacattagat gaggaaaaaa gtaacttatt
    14641 agtagagtct attcggatgc actataccga taaaccaatg gctattttta tgcttacacc
    14701 tgattatgat ccatctaacc atatcattgt tagtattttt cttagtcagt tatataaaga
    14761 attatctacg caatgtgtta agactaaagg agataaatgt caccgcagga ttcattttat
    14821 tttagatgaa tttgggaata tgccaccaat ggataatatg gaaggaatca tgacggtcac
    14881 agctggccga aacatgttgt gggatctgtt tattcaatct tatcagcaac tttatgcgaa
    14941 gtatggagaa caaaacgcag cgattatcaa agaaaattgt cagacacata tttatattat
    15001 gtcgacagat gataatacca tcgaagaatt ttctaaaaaa gtggggaata agacggttga
    15061 acaagagaac agtaccatca attcattagg tatgaatact catatcaatc gcaatgttga
    15121 ttcagatcgt atcttaactc ctgaaagaat ttctactttt ttagaaggag aaacgattgt
    15181 actcgctcct ttaaaacgac aagatttgaa aggtcataaa atacggccgt atcctatttt
    15241 taatcatggg gaaacgaatc ttccttatgc ttatcaatat attgaagatt tcaatccatc
    15301 gtgggatatc aatgatatag acatacattg tacacatgcg gacttggatc ttaaggcttt
    15361 acaaattgat tatgattatt tcctaccaga tgaatatgct agaaatctct atcatggact
    15421 gcatgatcaa ttagaagaaa aaaacgaaga aaatatgttt tataaaatcg ttcaatcttt
    15481 tgagaatgag acggctaaaa aattgttaat tcaattttac gaagaacaag cagcagatcg
    15541 acttcaagaa tatgttgaaa agttgatcaa aaataaagaa atttctgaaa tgattgggaa
    15601 acggttgtta ttggaatctg aaaaggtggt gaaagaatga tcattggagg aattttttct
    15661 ggcatagccg actggtggtc aggcttattc ggagaagggg atgcaaaccc caaaaccgta
    15721 acgaaagtct tacaagatta tgggaattat ctgcagtatc aagatgtatt tagttggatt
    15781 tggaacactt ttctgtgggg attgattaaa ggattatata atctcaatac tttactagaa
    15841 aaaaccattt atcaaagctt tgatttaaaa gacttattga acgccgctgg ggtaaatgca
    15901 ctatttcaaa gtttgattag taaggtattg gctctttttt gtgtcgtcac attaatttat
    15961 ttaggcttga aattttttat gagtaaacac ccaccaaaag tcaaaaatat cttggttaat
    16021 ttatttatgg ccatgatctt gatttttggt ggtagttctt taatcgatga agggttaaat
    16081 atcagtaaaa gcttttacgg agacgtcact gcagcaaata aagcagataa aacgggatca
    16141 cctgcttttc aaattattca aaataatgtg atcgatgtca gtacgttact agcaactgac
    16201 ccgaataaag tagaatccct accaacagat aaaagaaatg ctttaacagc gaaaaatttt
    16261 aaaacagcga atatcaatgg gattattact cctgaacaag ctaaaggtat ggcaggtaat
    16321 gataaaagtg ggttatcaga tatacaaaag gatcggttaa aggcattaca ataccgattg
    16381 gaactagatg ataatgggaa agaaattcct gttcaaatta gtgacgaagg cttagcaaaa
    16441 tatgtctata cttcagggta tcgtcgatac agtagtaaac caggtattat tttagctggt
    16501 gaatcttctt tggcagtagc ctatttattt atcctattta cgatcgttac ttgcattatt
    16561 gagctggtat ttaaaaaatt ctatttagtg attgccgcgt caacggactt tgagacaggt
    16621 caacggatga aaagtgcgat agaagatatt tctcaatcct tcttgttatt ggcgtttacg
    16681 attttagaat tacgaatcta taccttaatg ctttcaggta tcggtgattt gcatgcggca
    16741 ggaaagatca atggattctt gtatgtcgtt gctttgattg tactaaccat tgcgctattc
    16801 aaaggctctc aatcagttac gaaaattttc ggcgttgata caagcctgaa aaacggcagt
    16861 aattctcttc ttagcatgtt tgccttagga aatattgcga aaaatgtggg tagcggagct
    16921 aaaaaccttg caagtgctgg taagagtggt ttaagccatt taaatgatat tcgtaaaaat
    16981 ggatttggcc atcgaaaaga tgttacccct gataacgggg aagaacaatc agacgataaa
    17041 gctacaactg tacctaatag taagaaaaca gtttccgaaa tgttcgggaa agcgaaaaat
    17101 ggtgtttcta aagccgcaga aggtcttggt tacgtcaatg aacgtgggtt aaaaggaaca
    17161 gctgaagatc ttacagaaaa agccaaagac accttagaag ataaattaga cggcacgaga
    17221 gctaaagaat tggctgaagc tgtgaagaat ccatccgaag cactagaaaa acaaaaagaa
    17281 aaagcttcag aagtcaaaga aggactaaaa gatgcgtatg gtgaaggaca agtcaatgca
    17341 gcagtgaaag ctaatacaac aaccgaaaaa gaaaatcaag aaggtatagt gattccttca
    17401 gtcaaagatc accaagaagc gttgcactct aatgaaaatt cgattgaaga gaaaaattcc
    17461 atagaagaaa gaaattcaga agaaggaaaa aatggacagt taccaaaaac tgatccagaa
    17521 caatatcgct ataaacctaa cagtgacctt gaaaatgaga agcgaatttc agatttatca
    17581 aaagtaaatc aagaagacaa agcagaaaat gagggacagt taccaaaaac tgatccagaa
    17641 caatatcggt atagatctgt taactccgaa aatgaaaaac gcatttcaga tttaccaaaa
    17701 cgaaatcaag aagtacaaac ggatgaggat tccatcgttc tgccaaatga taatggaatc
    17761 gaagttggaa ctgaaaaatc aacgaaaatt ggtttaccta aggcacaaaa tttaccaatg
    17821 aaagatagtc gtttgaatca attcaaggat aatgatcaaa gttttgttca tcaatcacct
    17881 gcaggtactg ttcaaatgaa accaagtcgt ttgcctgaaa atggaaatct gacaactgtt
    17941 tcttacaatt tatctgaaag tggtgagaca gggaatgcgt ccgttcaaaa tgttgtgaca
    18001 agagaagctg caccaaaacc tattcaaaac gttcatacag gttacaagcc agcaaatgtg
    18061 gcatttactg caccaacaaa aataaatgtg acaagagaaa caaaaaacag gaacaatgca
    18121 ttgaaagaac aactattgag ggatatcaaa caggatatca aaccataaaa ggcctacaag
    18181 ttaggccttt tttctatgta tgaaaaggag aaatcattta tggataaata tagtaacatg
    18241 aaaaaccctc caagatttag tggagaatgg aagtttttcg cttttttctt tttagatcta
    18301 ttaacgcttg gtggctgctt tttttgggcg aaaatggtca ataatcttgt ccacttacca
    18361 ctcttttttg cactcttgaa ttatggctta tggattgcga tagcgttagt gattgtttgg
    18421 cgaccctata ataacccagg tcaacgacaa atttttgcga ttatcgagtc tatttttttt
    18481 gcggacaaga accattatca tgcgttagat cctaaccgaa attatcatgg tacgtataag
    18541 gaggatgaat aaatgcgagt caaaggacaa aattcagttg aaaggaaatc cattttgcag
    18601 tttggaaaac cagaagagcg ctctatcttg gacttatttc catataaatc ctgtacagaa
    18661 gagggagtct taattactag agaagatcat tttcaacgtt attatcgtgt agtttctaca
    18721 gacgtggaag gattaaatga acaagagaaa ctagaacgaa tgaatcagtt gaccaccgtc
    18781 atgcgtacgt atgtgccaac aattaagtta gttagtttga ccacagagac ggatctaacg
    18841 gaacaaatcg tgcaaaagcg gcaattatta gataaaaatc gtatggaaca gtccttagga
    18901 agaaatctac aacgattaaa aaaatatgaa aagaaattag tcgaagaaat ccaggaattg
    18961 aaacgagcag aacaagaacg tcctgactta agcttctttt tcgtcattga aggaaagaca
    19021 atcaaggatt tacaaaccag aaaccgtcag ttaatgcgat ctagtggcat tttagggtta
    19081 aaaccactct acaaaaaaga attgatcaag attctgtatc gaatgaacaa tatgaatgat
    19141 gagtaggaat ggagaagaga gaatgaaata tccgttgata tggttagaaa aagatgttcc
    19201 gaaggaagag accactagaa aatttcctca cactttaagc ctgggtaagt tgggaaaagg
    19261 gcaatctttt aaccaagtaa agaatcaaac aagaagaggt gactgtacat gttagaagca
    19321 attaaaacag ctttttcacc acaaaatgat caaaaagtac ttgatccatt aaagcaacta
    19381 ggaaatcggg aaatagaaat tgtaaaatcc aaagggtatg atttagattt tttaaaacaa
    19441 gtgatgccac aaggtgggtt aaattttgat gaagaatatg tgacgtatgg taatggttat
    19501 tcacgatgtg tgacagttta tcactacaca aaaaatccta cgcttttttg gttggccaat
    19561 ctcatgaaca atcctcatac agtggccaca ctcgatgtta gcacagatga aaagcaaaaa
    19621 gtgattgatc aaatcaatcg tgccttagat gaattaaatg atcgatcaga taatgaacga
    19681 aaagcgactg accgaaataa aagcgcggaa gaatacctgg aactagcgga atatgctaga
    19741 aaattgactt ctaatgggga aatttctaag caagtcaaag tgagagtaca tgtttacgga
    19801 aacacgattc aagaagtaga tgaacgagcg caggaactga tcgaaaatct caaagggatg
    19861 gattatcgtg cggtgactta tctgcataaa accaaacgag attggcaatc gatgtttacc
    19921 atgttcgatg aacaagctga atggttcgga aatatcaaag ggcaatcact accatcgtta
    19981 aacattggcg gaggtttccc gttccaccac caaacgctaa aagatccagg agggacacaa
    20041 tatggggaaa ccatgacagg cggcccattt gtctggaatg cgacgtataa aaatagtgta
    20101 cggttgtcta ctaatacctt gcttctagga atgatgggag ctggtaaatc gaccgttctt
    20161 aaaatgatcg cggaagccca tttagctgca ggagacttta tttggggctt tgaaaaggga
    20221 aaagacttta ttcctttctt aaaggaatat aacggtatta tggtgcgttt agacggatct
    20281 gacggaatga tcaatccttt agagatattt gccacacgga cgtatgatga agcatccagt
    20341 ttatatgacg atggatcagt caaagatttg aagatcaatg aagcagcgtc ctatcaaaca
    20401 cacttagaca aagtggtcta tcaggtacag ttagtgagtc ctcagctaaa aggaacgatg
    20461 aaagcagaat ttaagaccta cttaaatcgt ttttatgaag agtatggaac agtaccacgc
    20521 ggctttactt cctcaaattc gcgttcaaat actgatacgc aagtcacagg gaaagatcca
    20581 gaagcttatc cgacgttcaa agaattttta gactttttag gacaactgga attaccaggt
    20641 gcttcccaag agaaaaagaa tcgaaaagaa gaaatggaat ccatcgtaga atccttatgt
    20701 gagacgtatg gcatgatttt tgatggtcat agtacgattc gacaccttga ccaacaacag
    20761 ttggtctttt ttgacattga ctctattaca ggcttagatc gaggggtaca acaatgtcaa
    20821 atgtacatgg ctatgacgtt gatttggaat caggcattga ttcaaggaag aagacaacga
    20881 cgtttaatta aagaaaaaca aatggaagaa caagacttca aacgcttctt ggcgatgatt
    20941 gatgagtgcc ataatggtgc gacctgttct gcagtgaaaa gctgtgggtt gcaagtagtc
    21001 taaaaactat tgtaataact cttataacga gaagtcaaat gagtgggtaa cgccacaaag
    21061 ggcttccact gatactccga catgcaacaa gtagtttatg cagaccaacg ttgtgtgaag
    21121 ctcggtgaag tcggctgaag gataccgtaa ggtaaaagaa atagtgaata ccacgaaagt
    21181 tctctagagg taaagggtgt atccgataag tcgggtgtcc aaaaaaactt aatatggtga
    21241 gtatgtacaa acgtactgac gaactagcga atgtactgtc cgaaaggcat agctcctaga
    21301 aatgggagag acagtgagca aaaaatcact cattgtgcta acttgtggtt gagtaaaagt
    21361 cgttgttatg aaagaccatg ctgcgttaca ggcgtaggag aagttagggg gcaaaagcta
    21421 gcatctaagt taaggcatgt ggatagatat aagggaacag gggaagccat caacatggag
    21481 agtgcatact cgatgaagtg gtagtaagaa atatgtgaat gacaaataac ttactttagt
    21541 gatggtgaaa gtagagtcac gactgatgaa ggttctgtaa tggaactgga ggaacaggct
    21601 cgattcgtct gtaaaagtca tgaaacccgt tcaaccatgg gattctcgta tgactaaaaa
    21661 ggtcacgagc caattggagc gtgataaacc atgacaaaag aaacaagtcc aaaagatagg
    21721 aagttgcggc atgcagaata ttatggcatg acggaaatct tcgataagat atactccaaa
    21781 agtttgaagg gagataattt caagaatcta atgcagatta tcatttctga taacaacatt
    21841 gtcctagcat atcgtaatat caagagaaat cacggtagtg tgacaagagg agaagatgga
    21901 gtaacgatta aagatattga aaatctcaac cgtaatgaat tcgtagaaat tgttaggaag
    21961 cgattcgcac attataaccc tcggaaagta aggcgtgtag aaattcctaa atataatggt
    22021 aaattaagac cgttgggtat tccatcaata tgggatagaa tcgcgcagca atgcatctta
    22081 caagtattag aaccaatatg tgaagcaaaa ttcaataatc acagctatgg tttccgccca
    22141 aatagatcag cagaacacgc aatagcagat tgtatggccc gaatgaatca aagtcacatg
    22201 gaatatgtgg tagatgtaga tatcaaaggt ttcttcgacg aagtcaatca tactaaactc
    22261 atgagacaaa tctggtctat gggtatacga gacaaacagc ttctcttaat cattaggaaa
    22321 atgttaagag cacccgtagt acttccaaat gggaagttga tatacccaac aaaaggaaca
    22381 ccacaaggcg gaatacttag cccattactt gcgaacatca atctcaacga atttgactgg
    22441 tggatagcaa atcagtggga ggaaaaagat gccaaagagc taaaacatca ttttaggaaa
    22501 aatggagctt gggataaagg taatatctat cacaagctca gaaagagtac aactctaaaa
    22561 gaaatatacc tagtgagata cgcagatgat tttaaaattt tctgtagaaa ttataatgaa
    22621 gcgaaaaaag ttttctatgc aactaaaatg tggttacagg agcgtctaaa gttaccaata
    22681 tctgaagaaa agtcaaaaat cacaaatctt tcaaaagaag aaagtgaatt tttaggcttt
    22741 acgatgaaat tagtgaccaa aggtaacaaa aaggttgtta atacgcatat aggtacaaaa
    22801 gcacaaagca tgattaaagt gaaactaaaa aaacaaatca aacgaattca aaaaagtcct
    22861 aatagcaaag atacctttat ctatattgga gtctataaca gtatggttat tgggattcat
    22921 aattacttca aaattgcgac tcattgtagt gtagcaatgc gaaaaattgc aagagaactc
    22981 agaccaagtt ttgaaatacg actacgagaa caaggaatct caaaagaagg acaatacgga
    23041 aagtacgaag gatacaagcc ttacctacgg tcaggacaaa tacgatatat aagagggttt
    23101 ccaatattac cagtagggta tattcaacac agacatccga tgtgtaaaaa aagaaatatt
    23161 aataaataca ccgaagaagg tagggaagcc attcataaga agcaacaaac cgtagaagaa
    23221 tggaagatat cgtggttgtg tagcaatcca gtgcttagta agagagcaac gattgaattt
    23281 gcggacaatc gaatttcaaa attcatcgct caaaagggaa gatgtgcagt aacaggtgag
    23341 gagcttatct tatctgaaat gcattgtcat catattatcc cttatcatga aagcaaaagt
    23401 gatagctatg aaaacctagt gattgttact gaggaggttc atcgggtaat acacgctaca
    23461 caaagtgaaa cgattgagga acttctaaaa tatctaaaat taaatccaaa acaaaaagaa
    23521 aaactcaatg agttgagatt aaaagttggt aacgaagaaa tatcttaata aatatttgta
    23581 ggacgggaaa acagaatgtc ttttatagac gagggaacgc cgtatgcggt gaaagtcgca
    23641 cgtacggtgt ggactggggg aaaagacgga gataatatca aactcttacc tatcagtatc
    23701 gattaatcca gattttattg aaacggtaaa ttatgtcaca aactttcaac gagaaatgcg
    23761 taaagtagaa gcaatgactg ttttagctac acaatcccca caagaaatgg tgccagaaaa
    23821 tatgtcttct gataacttct cgaaactgaa gaaagtcttt gaattttctt ctacgaagat
    23881 ctttatgcgt atggatgaat ctattttacg tcatatagaa ggattagtgg gtaaatcaat
    23941 gacgaactca gaattagaat ccattcctca acaaaatcaa ggagacgctg tgatcaattt
    24001 tggctcaaaa gaaaccattc gtgttcattt tagtccgaac aaacgtcaat taaaattgtt
    24061 tgatggagga aaataatgga aaaccaaaat gaaagtttaa tcaagcagta tgttaagcgt
    24121 cgtgcaaagc ggcgcttatt tttgtggttg tttggtactt ctgcaggttt gattactatt
    24181 ttgatcactg tgttcgtgac cctatttcta atacttgcgg cgggctcgat tgataattcg
    24241 gattcagatt caagcagtgg tggcgaagct tttacaggag aatattcgga aggcttaccg
    24301 atttataaag aaatcaaagg aagaggccct ttttctgatg agattgcgca atatgccgta
    24361 ggtgcagcag tgaaatataa attattacca agtgtgatcc tttcgcaata cggttacgaa
    24421 tcagcgtttg gtacatcggc gtccgcaaga aatgatctca actattttgg gattacttgg
    24481 tttgatggtt gtctgtttcc taaaggaact gcacgaggaa ttggtggcat tgaaggtggc
    24541 tggtacatga agtttcccaa ctcaaaagct gcattttcct attacggctt tatggtagcc
    24601 acacaatcca attttaatgc ttgtgtagga aataaaagcc ctggcgcaag cttattgatc
    24661 ttaggacgag gcggttatgc cgctgcagga attacggaag atagtccgta ttatacaggt
    24721 tgtatgtcaa ttatcacttc taataaatta accgaatatg atgaattcgc catcaaacat
    24781 tggggtgaag gtggcaataa caacggcacg attactggtg aatggacgaa tccattccct
    24841 ggcagcagtt tagataaaag ttccttcagc ggtggtcaat tatttggaac gaatccaggc
    24901 ggtgaattcc gtccgaacgg cttccatgat ggattagatt ttggttcagt tgatcatcca
    24961 ggaagtgaga ttcatgcggt tcatggcgga aaagtcgtgt acgttggcaa tcctggtatt
    25021 tcaggtttgg gtgcgtgtgt gatcgtgatt aattacgatg gcttgaatat ggtgtatcaa
    25081 gaatttgcaa atagtacagg aaattctcga gtgaaagtag gcgatcaagt gaaagttggt
    25141 caagtaattg ggatacgaga tacagcacac ttgcatttag gatttactcg aatggattgg
    25201 cgtcaagcac aaggacatgc attcattgat gatggtacat ggatcgatcc gttaccattt
    25261 ttgaatagca gtaaaaaata gatcaggaga aaaaatatgg aaaataaaac gttaaaaatc
    25321 gtcttaacag ctgcaattag cgttagttta atcggcaata ttgcgttgtt ttggcagctg
    25381 aaagaggaac aagcagcaaa tacctataaa attgaagaag tggctaaaaa cgcgtctgag
    25441 aagctcaaaa aaaattcctc tgaggcacag gcgaagatcg acaagttaaa tcaaaccatc
    25501 aatgagaaaa accaagaaat cgatcagctg aagcaacaag atggcacaaa agcaaaagag
    25561 gaagtaactg aagcacaaag aaagacggca gaagagttcg gtcaattggc cattgataaa
    25621 tcattaagca gaaatgaatt aacggaaaaa ctaaaagatg tcgcaaccca agaagtgatc
    25681 gacaaattaa gtcctacaga cgatgatcac caacatgatg attacggaag ttactccttt
    25741 acattaggtg acgtgcaaac ttacgctcaa acaagcagtg taaaagagga acaaaatttt
    25801 gtcgtatttg ttgattatac aatcggcaat ccgcaattca aagatgtcaa accacaaaaa
    25861 ataaaaggtg gattaactgt cactgaaaaa caagtagatg gtcaatggaa agtcatagac
    25921 tttagttatt tcactcgtta ggaggaagaa aatgagtaag aaaaaaggag aaagacaacg
    25981 tttcaaaaaa cgaaaaagtt atcttagatg gctgggaatc tttatgattc tcggcttttt
    26041 gattcttgct agtccgattt atacgaatca gaaggtagat ataccagatg aggtaagcac
    26101 gaacgccttt ttaaacacga aagagctgac aatggtttca aaagaaaaag gagcgaacca
    26161 gcaattagtt tttgaatttg cgatcgatga tgaagatcaa agcttgttaa aagaactggc
    26221 taatcttaat tatcgcgtag aagtaaagac agctaaaggg gattatcaag caatacgagc
    26281 caaagtgatt aaggtgtctg atgattattt tgcagtgaag ctaacgcatg taccagaaga
    26341 atatatcgcc atgcgtttaa ccattattcc tgaaaaaatt gatccaaaag tggatatgca
    26401 agaaccacaa gatctgattt tttatattca cgaagataag gtcaaagatc acgtgaaaga
    26461 cgaagattat gaacaacatg cgatcaatta caaagtgaaa ggatacaaga aagaacaaaa
    26521 agcagctcaa aaacaaatgg aatctttcca agcaaccatt gatttgaatg aagaattagt
    26581 gaagaagcta aaagatcaat tgccttatca agtcgcagat gatcaggaaa atactgaaaa
    26641 caagattaat agctaccagc aagaaattga aacatcgaaa acgcaactga aagatcaaga
    26701 agagatcatt caaaaacttc aagaaaaaat tgatcgtatg acaaaagaaa agatttagaa
    26761 ggacaggtgg agtgaaaaaa tgaagcgaac aaacttggct gacaaagata ctttcgctga
    26821 gcagaaagta ttgattaaag cctatctcaa agttgtaaaa gctaaagaaa tatgtcgaga
    26881 agtgaattta tctaacacaa caatatctga gttgaagaat ggtcgaaaga atttagatac
    26941 cttaaaattc agatcatttg aagctctata tgtagctgct aaaaaatatt ttacagctga
    27001 taacaaataa aaaacaggag tattttatgt gaaaaaagta tataaaaaat gcttatgaat
    27061 cagctatatc accttaacca tttgttaatg agatgggaga aaacattaac cacgattcta
    27121 acgcaaacat caagcacata aaacatttaa cactcctcct ttctggctga agatttcaac
    27181 caaacaggaa gacagcgtat caattatagc atacactttt tcttaaattc atttttcata
    27241 tgacaaaata tttccttcta atcgacaaag ttagaaggat tttttattgt ctaaatacac
    27301 aaataacctt aatttttaaa gagcataagg aaacgtgata tcactttctc acgaaaggtg
    27361 ttaggtaggc tgtgcctacc acgtttctaa gaaagataaa tgatatcaaa attttggatt
    27421 tgtgtgtaga tttgtgggta ggatgaaagc gaatgtgggc agtaaaataa gcgtttgtgt
    27481 gtagcaaaat caaaaaatgt gtagggatat gtgtagctac acatatccct acacataata
    27541 aatttggagg aaaatatgga cttattaatt agaaatattg aagaaaagta tattaataaa
    27601 attgacaaac gttgtgaaga acttacggtc aagactggca aaaaatggag tcgaaatcaa
    27661 tacctaaaag ttttgatcga aaatgatttt gatcacgctc ttctgaatta taaaaaagac
    27721 caatttgatc ggttgttaga aaaatttgtg gatattcaaa cttataatac gaaaacttta
    27781 gaagaatata ttgcaacaaa taatcaatta attggtttgt taattgaata ataaaaatag
    27841 tattgtgaat ttataaaagg aggaaatcaa ttttggcaaa agcaacaaga aaacatgtat
    27901 atctttacga tatgcatatc gaagtacttg atgaaataat ttctactcat gaagatatat
    27961 ctaattatag tgaagcagtc agacatttgt gtatgatgta tgatccaaaa atcgaagaaa
    28021 aaataaatcc aattcaaatt aaattgaatg caatgggaaa agaaatttct attttaaccg
    28081 aaatggtttc agagtttgcg gatcttcatt tgaaagatac aggaatacta attggtacaa
    28141 attcaactgt ttatcaagaa gcagaagaac gtgtggaagg aaaaattaaa tccaatcaaa
    28201 ccaaaaaata ttcttctaag ttaaagaaac cagtgaatga atctgttcat accagagtag
    28261 atccatttga tccaacgaag attctaaaaa gataaaagta gaaggagaac gtgatgaata
    28321 aatcgcctgc agttattctt acttgtcaat ttaccttgcc caataaaaaa tctttttcaa
    28381 catacattga ttatatgaca agagaaaaag cactggaaga aatggaacga cgtacgcccg
    28441 aagaagaaca ggaactgcaa cgaatcaaga atgctttaga ggatttttat attcctgaag
    28501 gagaaacttt ttcggaaagt aagacggata aagaattcag tgaaacgtcg aatgaagctc
    28561 aatcgttgat ggaacatgga atcaattttg acaagttaga ggaacaagat tttaccaaat
    28621 atctttctta tatgacccgt cactatgcgt tagaacaaaa gaaagaactg acgcaaaggg
    28681 aacaaaaaga ataccaacgg ttgaaccaag caatgaaaaa atatcaaaca gagccacata
    28741 aaaaagcttc aggaaatctt cctggagttt tttctatggc ttcagacgaa gtgaaaggaa
    28801 gtgatctgaa ggagatcaaa caaatcttcc aaagaggaca acaaaaaggc tcaatcattt
    28861 atcaagatgt tatctctcac gacaattcgt atcttgaaaa aatgggcttg tacgatccca
    28921 aaacagatac cttagatgaa gaaggtttga aagcagctgg aagaaaaatg atggagacat
    28981 tattcgagaa agaacaattg aatgaaacag gttactggat ggcaacgatt caccgtaaca
    29041 ctaagcatat ccatattcat tttgcagttg ttgaaaaaga aaatacgcgt aaaccgtata
    29101 ctgagattga aaatggtgtg agttatatcg taccgaaggg gaagagaaga caagcaacat
    29161 tagacgcaat gaaaaccaat tatgtacatg agttagaacg tttctcttat gaaaaggatc
    29221 gaatgatcgg tatggagaaa cgaaatttat tgacacgaaa aagtgatttg cgtaacacct
    29281 taacaaaagt agtaaaagaa ccagcacgtt acgatcgaca cgccatgaac ttattaaatg
    29341 aagtatataa aaccctacct gaaaaacgtt cggaatggaa ttatggagat gaaaatcgaa
    29401 ccaagctttc accatttaca aggggaaaac ttgatgagtt aaccaaatat gttttaacaa
    29461 aagaacctgg atatcaagaa tatatacaga tttcaaaagc attgaaagaa gaagccaaaa
    29521 gcctttatgg ggaaagcaaa agagaaacaa agaatgcaga aaaaaacgcc ctctttgatt
    29581 taaaaaagcg cacaggaaat gcgattttaa cagaactgaa gagacaggat agtcaaataa
    29641 aaccattaat agaaagtgtc aatcagatgc aatctattta caatgaacga tcctttcgaa
    29701 cactcaaaca gttgccaaca aatgaataca agtatagtta tcaagaattc gtaaagcgta
    29761 ggaaacaatt ccaacaaaga gttgtcacgc agcgaagctt gcgtcaatta aatcgaacaa
    29821 ttaatgcaca tgaagaaaaa taccacgcaa gtaaagcata tgaagagcaa cagcgaagaa
    29881 tccaaatgga acaagaaaga caataggagg aagagaaatg aaacaatatt tagatcaatg
    29941 gaaagtcata gaaggatcac taaaagaaga acgaatcgaa caacttcctg attgtttaga
    30001 aaaagagcat ttgtttcaga taagcgaaat gttgagaaac gaacagtttg atccaaatca
    30061 atttttagtt gttgagtacc cagctactgg tgtgtattgt tgtaatcatg tgaagggtga
    30121 aaaatatttt attattcaag aatacgaagg taagttagcg ccttattata ctacttggga
    30181 aataaatgaa gagggaatca ataatttccc atgtgaaagc attgaagagt ctatttctct
    30241 cacggaatgt taaataaata gagacgtaaa agagtcctga acgtgattgt ccaggactct
    30301 ttttcaatga attgttttcc gccaattcac tgagtggtgc gattcaattt tattatatca
    30361 aaagaaagtg agattccaaa gtgaagggag gaagaagaaa tgactcagac aacgattggt
    30421 gttgtggttg aaaaaagcag ggataatctc gtttttgtga cagaaattca aacaggtaga
    30481 gcttttgtag tcacagacaa agctgcaaaa gcgtatcaaa atggcaatat tttaacgtta
    30541 aatctgacta cgaagatgtt cgttgatgca gtagaaaatt atccatttgt ttagacaaac
    30601 gatattttac aaggaggaaa cggacatggc agaagaaaaa gaaccactag ataatagtcg
    30661 gttgggaaag tccaaaagaa aattagtacg gttgcaaaac gaattaaata atcaatttca
    30721 aaagctattt gatcaccaaa aattgacaaa tgggcaacca atgaatgaca aacgaaatgg
    30781 tcgttcatgg tttaaccagc aagaaaaaat agaaaataaa atacaaagtt tgagagaaga
    30841 gatcaagcaa caagaaaaac aggtagaaaa acttgaaaga caagaagagc taaaggaaat
    30901 gggctataac aagtacggcg gactggatat gacgatcgat aatattccaa gaatcaaaga
    30961 agaaatcgaa cgctttgaaa aaggtgaatc gactttttca gccgccacga tccgaaaata
    31021 tcaacggaag ttggaaacat tagaacagct gaaagaaaaa tcagaaaaag gaaaagaaaa
    31081 tatcctccct gaagtacaag cgatcattga cagcggacga gtgacgcaat ggaaaaaaaa
    31141 tccaaccatt tattttttga aaggctatcg aaaagttgct ttagaactga atgaaaacgg
    31201 gggatttgag gaatcaaaaa aataccaagc cacgtcggaa gaggaaaaag cagctgttcg
    31261 tgaattactt gaagaggctg caccaactga ttctctgaag gagaaagaaa aagatcattt
    31321 ctatcgagta gaattcaacg aaaatgatcc agaaaaagga ttgaaaagtt atggtgggga
    31381 gatcgtaaca ttagaattga tcgatcaact taaaacgttg gataaccaat acgctgcaga
    31441 agcaggttat tataaattct attttgaaga agtgaagaac ggagaagtag tagatcagat
    31501 ccgaatggat ctaggggatg gcgtcaacag taatcacccc atctatttag agttagcaaa
    31561 attgtgcgaa caagtacctg agaaggaaca aaaacaatcg gtcaaaaatg aacctgtttc
    31621 gaaagaacaa atgcagtcga aagaaacaaa aacaaaacaa aagggctatc aaaaacgaac
    31681 ggcagaagag atcaaacaag aagttaaatc cctttcgcaa caggcactgg atgcggtgaa
    31741 aaagcatacc cattcttctg aagacgtcaa agaacttttg aactttatgt ctcgttttcc
    31801 agaacgatcc tttagaaatc aattattgat tgaggaacaa tttccaggtg caacggcttg
    31861 tttaggtcgt gccgcgttga aaaaagaagg aatctatatc aaaaaagggg aacaagggaa
    31921 caagatcttt gtcagaaaaa cggtcaaagg attttatgag aaaggacgtg gctttgttcg
    31981 agaaacagaa gctacaccag aagataaaaa acgaatcgaa agtggtcaaa tcgaagtgat
    32041 caaaaaacct tactacacga ttgaaaaagt gtttgatatc acacaaacac agttaaaacc
    32101 tgaagactat ccgaaaatct ttccgaaccg tgtctttgat tttcaattgg ataaaaaagg
    32161 acagtcagaa cttcaagctg ggattcaagc ggtagccaac aatattggaa tacaaattcg
    32221 agatatgaca gaaagtgaag tctatcaaag agaattagga caagcacgtg gggcgtatgt
    32281 tcgtaacgaa tttactggcg aagaagaaat cgtcatgaat actcgaaata ctcctacgca
    32341 gcatttagct acaagtattc atgaattagc ccatgcaaga atgcacaaat tttcagaatt
    32401 agataccgca actaaagaat tgcaggcaga aatgacttct tatattgtgt gcaaacattt
    32461 tggaatggac acttcggaga aagctattcc ttatattgca gcatggacga agaatggtca
    32521 gacgttggat gataaggaag cggcggaacg tgggaaaatc atgaatgatg tcagccgtgt
    32581 cgcaaatgaa ttcattcaaa ccatttctaa tgaaatcaat caatacagag aaagagaacc
    32641 agagatccaa ccagcagaag tgaagcagga gcataaaaat actgtagaaa cggcagagaa
    32701 taagaatatt gtgcccgttg gttcactttg gatcgacaag aaagacggga aagtaatgga
    32761 agaagatacg ggtcgaacgt tacatttgaa ggatgcggcg tttattgaag atccgcagca
    32821 taatcaagtg attttaaaag gaaaaagtta tggaaaagag attcaaacgg cgttaccttc
    32881 agaagaattt gcgctaggaa atccattccg attttcactt gaaacagtgt cagaagtggc
    32941 caaacgaaaa aatgaaatct attatgaaca acaattgtca caaaaagaac gcgtataaaa
    33001 caagtaaaaa agactatctg aaaaacggat agtctttttt cttttgggag gtttgaaaat
    33061 gaccgaaaaa aaaatgagtc ttattgatcg atgtaaacag atcgatatag tggattttgc
    33121 tcgaaacaat ggaatggctg tagtcaataa aggacgagac tatcgcttag aagaccatga
    33181 ttcatttgtt tttgatcgaa gaaaacaacg tttttattgg aacagtcaaa atattagtgg
    33241 cgacattatt gaattagcta aacttttttt catagacaaa gagatccaag actctaagca
    33301 acaatttaaa gcagccactg attttattct aaagaatgaa gacaaaacag aacgagtgga
    33361 aaatcttcat tttgaaacag aaaagtacaa agatcacccc gttgattatc aaccactcac
    33421 agaaaaagga aggaattatc tgaaggaaga acgaaaacta ccagagtggc tgattgatta
    33481 tgcagaaaaa gaagggttga ttgccgaact aaagccaaaa tatgaacggc aaaatttctt
    33541 agttcgagac gatcgtttag atcatgcggt cgccttttta tggaaagatc cacagacaaa
    33601 agagacagta ggggcgagtt atcaaggaac gttcattgat tatgaacgtt ttggtgagag
    33661 aggcacatat aagcatatag ataaaaattc gacagcgaat catggcttta acctaaagat
    33721 cggtgaccct aagcagttaa aattttttga gagtagtatt gatttactta gctatgctgc
    33781 actgaatcgt gatcagttaa acgatacgtg gttagtctct atggaagggt taaaacacca
    33841 tgtgatcagt cattattttg gtgaggcagt atctgaattg agaaagaaac aagcctttcc
    33901 tcaatccatc gagatttgtg tggataatga ccgtgcagga catattttct acgaaaaaga
    33961 acaattaatg ggcgcagtcg atccatttac gaatcagaaa gtacgttgtg aacgaggaat
    34021 cgctaatgat tggcaagtgc caaaagaata caaaatcatt tatgaagaag tcgcaaaaga
    34081 agaaaaggtc acaccagaag ctattatggc catacacaag acagaaaaca atctgcaatt
    34141 aacgaaccaa ctggtttccg ctcacaaagt aaatgcgttt tttggccagc agctttctgt
    34201 taacgattca atagaagcca ttaatttgaa agatatttgt agagaagtcg caaaagaatt
    34261 aaaagtttgt gaacgcgtgg atggtacgta cgattttgat cgtttttatc aagaaaaagg
    34321 ggatattaat gcgcagattc ttttctctta taaagcagaa caatactaca aaggctataa
    34381 aaatcatgaa catgaattta tacctgaagt aaaaaaggac tggaacgatc aattgaagca
    34441 tgagatccag caacaagaaa tcagaaagca aaaacgtgcc atgttgtttc aacaaggcag
    34501 acaacaagaa agggagtgaa atcgtcatga tgaaaaccgt tattttagca gaaaagccgt
    34561 cacaagcgaa agcttatgcc gatagctttt ctaaagctac ccgaaaagat gggtattttg
    34621 agatccaaga tcgattgttt acaggagaaa ctgtgatcac gtatggtttt ggtcatttag
    34681 tcgagttaga ttcgcccgat atgtacgatg aaaaatggaa acaatgggca ttagaacatt
    34741 tgcctatttt ccccaatcaa taccactatc atgttcctaa agataagaaa aagcagttta
    34801 gtgtcgtcaa acgacagctg cagtcagctg atacgattgt gatcgcgact gatagcgatc
    34861 gtgaagggga gctgattgcc tggtcaatca ttcaacaagc aggcgccaat caaggaaaaa
    34921 cctttaaaag actttggatc aactccttag aaaaagaagc catttatcag ggattccaac
    34981 agttacgaga cgcagaagag acctatccaa aatttgaaga agtacaagca cgtcagatcg
    35041 ccgattggtt aattgggatg aacggtagcc cactgtatag tttactcttg cagcaaaaag
    35101 gcataccagg aagtttttct ttaggtagag tccaaacccc aacactctat atgatttatc
    35161 aattgcagga aaagattaga aacttccaaa aagaaccata ttttgaagga aaagcccaag
    35221 taatcgctca aaatggcgca tttgatgcga agcttgatcc aaatgaaacc caagcgacac
    35281 aagaagcatt tgaagcctat ttaaaagaaa aaggtgttca attaggaaaa cagccaggta
    35341 cgatccttca agtcgaaaca gagaaaaaaa gtgcggctag cccacgtctt ttttctttat
    35401 cgagccttca gtctaaaatg aatcaactca tgaaagctag tgccaaagat actttggaag
    35461 ccatgcaagg gttgtatgaa ggaaaatatc taagctatcc gcgaacggat accccttata
    35521 ttacggaagg ggaatatgcg tatctgttgg atcacttaga cgaatacaag cattttttaa
    35581 aagccgaagc gattccgact cctattcata caccgaatag tcggtatgtg aataataaga
    35641 aagtccagga acattacgcg atcattccta caaaaacggt tatgacagca gcggcttttg
    35701 aacaactaag tccactgcag caggctattt atgaacaagt gttaaaaaca acggtggcca
    35761 tgtttgcgga aaagtatacc tatgaagaaa caacgatctt gacgcaagtt cagcagcttc
    35821 agttaaaggc aatcgaaaag gtgccgctag atctaggttg gaagaagtta tttggaaaag
    35881 agagcgacgg aaaagagaag gaagaagagc cgctacttcc taaagtgaca aaaggagaaa
    35941 tggtgacggt ggatctacaa gttcttgaaa aagaaaccaa gccaccacag ccttataccg
    36001 aaggtacgtt gatcacggcg atgaaaacag ctgggaaaac cgttgatagt gaagaagcgc
    36061 aatccatatt gaaagaagtg gaaggaatcg gtacagaagc gacacgggcg aatattattg
    36121 aaaccttgaa acaaaaggaa tatatcaagg tagagaaaaa taagctcgtg gtgacgaata
    36181 aagggatttt gctttgccaa gccgtggaaa aagagccgct gcttacgagt gccgaaatga
    36241 ccgccaaatg ggaaagctac ttgttaaaga tcggtgaacg aaaaggaaca caaaccactt
    36301 ttctagccaa tatccaaaaa tttgtctctc acttattgga agtcgtacca gggcaaatcc
    36361 aatccactga ttttggatcg acgttacaag aagtgaaagc agccagtgaa aagcaagaag
    36421 ccgcgcgtca tttaggaatt tgtccaaaat gccaggaaca agaagtctta ctctatcaaa
    36481 aggtggcagc atgtacgtct gaagcctgtg atttcaaact atggacaacg attgccaaaa
    36541 agaaacttac agcgacacag ctgaaagaga tcattcaaaa tagccgaaca agccaaccag
    36601 tgaaagggtt aaaaggtcag aagggttcgt ttgaagcaac gattgtttta aaagaagact
    36661 tcactacagg ctttgaattt tctgaaaaga aaaaaacgaa cttcaagaaa agaacacgac
    36721 gcactacaaa ataatggagg gttaatctta tgcgtaatac aacacacaaa caacaagaaa
    36781 tcgaaaatca aaaagccaaa attcgttcag aacaggaaaa aatgcgtgcc agcaaacgaa
    36841 gactgcagca attgaagaac cagcagcgga ttcaaaaaga aatcgaatta gatcgataaa
    36901 ttcctttctt gttaatataa aactaacatg ttatagttgt gttagtttta tattaacttt
    36961 aggggaagag taatgaaaga caaaatccaa tgtatttttg ataaacataa tggcaaccta
    37021 tccttgaagg atgctagaag tgaaggatta tcgcctatga cgttagatcg attagccgaa
    37081 aaggataaaa tagaaaaggt agcaccaggt ttctatacct taaaggatgc gttcgtggat
    37141 gaattgtatc tcgctcagag tatctattcc agagggattt tttctcatga gactgcgctc
    37201 gatctttttc aagtaggaac atatatccct aaaaagatca atatgatgtt tcctaaagga
    37261 tacaatgtat caaaggagaa attagatcag tatgccattc aaccgcatta cactaataaa
    37321 gaaaattttg acctgggagt cacagaaaca gaaagctttt acggcaataa aattttagtc
    37381 tatgatttag agcgaacgtt atgtgacatg tggaatccaa gatacaaagc aagcgtagag
    37441 gtaaaacaag aagcattaaa agaatatatg acaagtacca gtagaaatac aaataagcta
    37501 agaagataca tggatatttt aaaatcacca aaagaaatga ctttgtatat gttgccactt
    37561 tattgagagg agtaaagatg aatgacaccg acacaattta aagagaaaac aagaaatttc
    37621 gcagcagaga aacatttaaa cccacaaatt gtccaaagat attatatgat ggaaaaatta
    37681 ttagaatgta ttgttgaatc gccttatcat gatgattttg tattaaaagg gggatttctg
    37741 attggatcaa aatacgggtt agaaaaccgt tcaaccgttg atattgatac gacttatcga
    37801 aattcgaaac taacaaaaga aaagttagaa actgtttttt ctgaattaac agctaatcct
    37861 acaaaagatg gaattcgttt tgaattaaag ggattaacag agacgaggga agccgattat
    37921 tatccaggtt ttcaagcaaa gtttattgct tatcttgaaa atgcacgtgt accttttaaa
    37981 ttagatatta cttcaggtga ttctattatt ccagcagcat tgatgtatga acacaaatta
    38041 atgtttgaag ataaaacgat tcatattcca gcttatccta cggaacaaat tctagctgaa
    38101 aaattacatg ccacgtttag ttttggaaaa gataattcgc gcatgaaaga tttttatgac
    38161 ctgtatatga ttccgaaatt agaacgtatc gatgagaaaa atttgtataa gagtgttcaa
    38221 ggaacattca aggaaagaaa taatcaatcg gtgtttaagc atttgtatga tcaggaaatg
    38281 cctcaattgg tgaaagatga gggcttgaga gaaaagtgga aaagatacca acaagaaaac
    38341 tattttgcca aagacatttc tttcgaatct acactaactt ccgttgattc cctgatgcaa
    38401 tcaattgtag agcaagagaa ggcagaacga aaacaaaatt ttaagagatc acaacaaatg
    38461 aatcaagaaa tggagagata aagatgatca ataatgtaac tttagtaggg cgattaacta
    38521 aagatccaga tttacgttat accgcaagtg gcacagcagt ggcgactttt tccctagccg
    38581 ttaatcgtaa tttcacgaat caaaacggca atcgagaagc tgattttatc aattgcgtga
    38641 tttggcgcaa accagcagaa acgatggcga cattagctaa aaaaggcagc ttgatcggcg
    38701 ttgtcggacg aattcaaaca cggacttatg acaaccagca aggacaacgt gtgtatgtga
    38761 cagaagttgt ggccgataac ttccaactat tagaaagtaa agcagcgaca gaaagccgta
    38821 tgcacgctga tcaatcgtcc agcagtccaa gccctaccac ctttgaacaa cgggatacag
    38881 cgacgcctaa caacaatgga ttgaacgctt cacagaatcc atttggtgga caatcaatcg
    38941 atattagcga tgatgatcta ccgttctaag tagcattttc tattggttgc atttgctacg
    39001 gtttatgtta taatttagac aacaaaaaga attttcaatc tataaccaaa aaccactagc
    39061 tggcgggcta gtggctttct tttacgtttc tattataaga attaacgggt aggcttactg
    39121 tctttcttgg caaatttaca atcaagccat ttgcagatat agtgcgcggc tacttctgcc
    39181 atgattgcaa aaacaaaatc aaaaagaatt ttcaaaccta taacctcctc cccttgccag
    39241 attaggccgg ggtagcagac agcaagacta ttatagcata attgaaatat ccaaatgatt
    39301 ggatttttgc tataatttta gcgaggtgat tgtgatgaac aaatatgttg gtttgcttga
    39361 taaaatccga gtaataaaaa cgcaaccgtt attggttcgc tttactttac aaacgattca
    39421 tgaatcgatt aattgtgtag ttgcagatat tgaaattatc gataaattgc taattatgga
    39481 tgatggaaaa tacaatattg ccgtcacagg tcacttcaat aaacgaaatc agctagttat
    39541 tgctagcatg tatgttagaa atcccgatca ttttacgcga tcgatgggca tataaataaa
    39601 agaagagttg tagtcctaaa tgaggattgc agctcttttt gttttacata gaaacaggaa
    39661 aagacctttt taggaagaca caagtgcctt ctcaattgaa aaacctttct ctcactccaa
    39721 ccgccaccgc cgttcgagaa gaaaggaagt gaacgctgca cgttcactaa gatatggtgt
    39781 cttgcaaagc aagacaaaat agacaaaact tcctctcacc aaaaggttcg ttcctgttcg
    39841 ttatctcttt attgatttgc cagaccggca acaagttgcc ttttatcacc aaaaagcgac
    39901 aaggacaagg gtaaatggca cgctgcgcgc ccttgtcctt gtcgcttttc gttgatttat
    39961 tctggccaac aaatcaataa agaaagaact aacgaaagga agtaaaacct ttcctaagag
    40021 gaggcagaat caaacatgcg aaagaaattt gattattggg gtgttccctt cagcgaatta
    40081 ttcccaaact atcatgcacc acatactgtt gaatgcgatt gtggagaaag agcgaaatgt
    40141 atcaaaagct atcgtttgta tcaatgtcca acatgcggga aaaaatatac cttgtcttat
    40201 ggcgattaca ttttgattga tgagaaagga aagaaacgct gatgaaaaca caacacaaat
    40261 tattgactgt aaaagaagtc gttcaaattt tggtggacaa agaagtcatt tctgaaaaag
    40321 tagcagaagc tttacttatt ccgcggtact ggacgataga aaccccttta gtagaggatg
    40381 caccgactat gctatttgaa gacctagtga agattgcagg atatgaactg cattatcaag
    40441 aaaacatgga aacttatgaa atcgaatatt ggttaaccaa attagagaac taaaaaggag
    40501 aaaaaatatg gctcaaaatt actatgacga atttgtcaaa ttacctttgg ataaaatggc
    40561 acaaaaaatg gaggatatga cgttcctata ccatgaaaca cgtgtaccca aaaaacatta
    40621 caaggaaaaa ttgtcagtcg cagtggaaga aatgattgaa tcaggtgtcg aaatgaatct
    40681 cattgcgacg tactatcgaa cactggaaga actgaaaaaa caaaatggaa aatggttttt
    40741 ccaagcctta ctatgcttgg aagtaggtgt caaaccaagc actatcaaac cttccgaata
    40801 tcaagcctta gaactgactt atgcaaaatt cgcacagatt aagaaagcta aagcaatggc
    40861 tagcgactgg ctagatactt ttgaaagtat cgaaaaaaat ggtgcatttt atacgattga
    40921 atcggaggag aaagataatg aataaggtgg tttatcagct aacaacagaa gatgtttcgc
    40981 aatttttaac aagcaaagaa cacttgaatg aagtaatcag acggattcaa aaagacttta
    41041 gttgtatgga agaaatgaag tactttattc aaagagtgga agaacagttg tatatggaaa
    41101 gcgaaacaag tcaaacgaag gtcacagtca gccataatca tttagacgtg tataaacgtc
    41161 gtcctgaaac ggtaaaaaaa ggaacagagc ttctacgact agaaacagaa aaatacatca
    41221 tgaatgtgta cctagaaagg agtgagctgg tcgaaaactt tgtcagctac acgatttgta
    41281 ggaaacacta ttactcagaa tcagaatatt attcaatttt cgagagcatg gaattaatgg
    41341 aagaagaaat ggaagagcta aacagcaaaa atgcgacggt agacgattat taccttgtat
    41401 ttactaggtt tttgacgtgt gggacggaat ctatcgtgtt aatgggaatg gattatgaac
    41461 tcgctgtacc cgaagcattt ttgagggaat atgtagaaga agtagataac ccaggcgacg
    41521 actggtacac gactttaact gattttttag acacctacac ttacgacgat acagaagaaa
    41581 tccaaaatga acttgaccgt aaacgaatgc catatcaacg atttgaaagg aaaaaaggta
    41641 aataaccatt tataccgaaa agtgaggatg tgtgaaataa gaacaaaaaa ccttgaaatt
    41701 aagggaatgg ttcttatttc gcaccaatcg ctccaaccgc ccccgccgct taggtggtgc
    41761 gaaataagcg ggcaaagccc gataacctaa gagaaagaag gagatccata tgaataaaat
    41821 cattcctcta ttgttcgtac tgtttgttgg cgagatactt atgcgtcatg ctgcagctgt
    41881 acatttaaac ttcgtagtat tcttaggaat actggtattt tgtttgatct tttggcgatt
    41941 tgtattagcc cttgtgagtc tactattcaa gatgattgca gccatatttt tcatagggtt
    42001 atttcgatga aaggagagag tactaatgcc aattgcaata ggaaataaac ggttacccgt
    42061 gacattagat gaaaagagac aaaaagaatt gcagcaacta aagcagaagt acggaaaaag
    42121 tgaatctaag attatgtgta ttgcgttaga tctattgatc gcgcaagaaa aagcaggatt
    42181 tgatatacca gcactaaaaa agtgacgtca cttttcattt gaagaaacaa aagtgatagc
    42241 acttaattgt tcctactatt tagaatattt tctatgtcct ttttattcca ttttgtatca
    42301 ataactatga aatctttaaa gtatccagaa gagattattt ttagatcaat ttttttctta
    42361 cctgattcta aagattttgt tttcttaaac atattatgat ttcctttcga ctattttcat
    42421 ataaatgtta acatagttta tggattcatg gaatgttaat ctaatttaat agaaaaggat
    42481 aattaagtat atacgttttt tcttatgtat gttatactat gtatatacag aaagaggtgt
    42541 ctactatgga aatgttacct ataaaaaaat ggggaaatag taatggcctt agattgccaa
    42601 agtatattat ggaatatctt ggaattcata cagaagacaa agtgaagata atacaagaag
    42661 aagtaaacgg tcagaagcgg ctaattatcg aagcggctaa tatagaaaat gaattaacaa
    42721 ttgaacagtt atttgaaaat tacactgatg aaagaaatca tgtgacgatt caaaatttag
    42781 gtgaagcagt aggtaatgaa aaatggtgag aaaacctaga caaggcgata ttctattatt
    42841 gaatacagca cctcgatctg gacacgaaca gacaggtaaa agaccttata ttgttttaag
    42901 tcatgatatt attgcggatt atagtaacgt tgttacagtt gctccaattt ctagtacaac
    42961 tagaaactat ccgctatatg taaatataaa ctcagaatat gaaatgaaga caacaggaaa
    43021 agtattatta gatcaactaa cgacaattga ttatgaagcc agagagtgta tttttttgga
    43081 aaaagcgcat gatagtttag ttgaggagtt attgatgaaa gttagaacag tttttcaaaa
    43141 agtaagcaaa taaaatagaa acagcagcat gatcaactat tcgtgattga ccatgctgtc
    43201 tttttttatt ctatatacgg tttgtctcgt aacattgtag tcttttgcaa tcttagcgat
    43261 cgcaacacct ttttttagat cctcaacgat gtttttataa acaagacgac gttggggatc
    43321 ttttgcattg gcactgtata gcttaggacg tcctttataa acaccgttcg cttttgcaat
    43381 cttaatgcct tgtgcctgac gtcgtttaga ttcggtacgt tcttgttcag cgatcatggc
    43441 caaaatttga atgatcaaat ctttaatgaa tttatccagg agaggattgc caattgcttc
    43501 ggccatgatc ggtagacttg tgatgatcag ctgcacattt ttcttcttca agtaattgac
    43561 tgaagcgatg atctcgtcgt aatttcttcc aagtcgatca atagcttcca caataaaaat
    43621 atcttgatct cggacgaaat ccagtgcttc ttgaaaaaca agtcgatgag taatcgttgc
    43681 gccagattgt ttctcaatga aaattctctc tgcaccgaat tttttcattt cttcaatctg
    43741 ccgttgttca ttttgatcga tggatgagac acgtatgtat gcaactctca aaatttttac
    43801 ctactttctg caactattta aaaaacaccc taatcataca cgagaaaacc agatttttca
    43861 atgtcgcggt cgtgtctagt tagggtatac cttatataga caaaaactaa tgatggagga
    43921 aatagtatgt gtcacttttc tttttaaatg gcaatatttt ttgtaaataa atgtcaatca
    43981 agaaaattta aacgattatg acattaaaaa tatattttat gaattttcta gtatataact
    44041 tgatttatct gttaagattt attaagaaaa cgttttctta tttttgattt cgaggtgata
    44101 gacaatgaaa aataagttta ttttatcttt aggtatttta actattggaa ttagtgtaac
    44161 tggaactaca attcctacat ttgctgatag tacaaatgaa ccaactactg tagtagataa
    44221 taaccaagaa ttaactcctt tagataggaa cggaatagcc attggtaacc caactaacga
    44281 cttaactgtt actgaaaatt atttaatagt ttctccatta cttgctcgag cagcttctaa
    44341 aacgatacga gtgacaggaa cgatgatttt tgataaagtt ggttggcctt ctagacctcc
    44401 tcaatcacgg aattggaaag aaaaaagaaa tggttattgg tactatggaa aattgtattt
    44461 acaaagttat aaatcagctg gaaacaattg gattgcgact tattcaggaa ccttaactag
    44521 aaagtaggga ttttttatgc cagaatttgt gaacacacca aatttttatc aagatagcga
    44581 tattctaagt aaaattaatt taccgaaaga agaatcagct ttacaagttc agcgaacttt
    44641 acaggagaca caaaaaattc aaaaatcaat ttctaatcta gaagattctg aagaaaaaag
    44701 aaaaaaaaga gaccaaaaaa catatcaaaa agaaaaataa tgattttaaa aaaagagtgt
    44761 ctagtcgaca ttcttttttt ctaattgaaa gtgttcataa aatcacccat ttctggacac
    44821 tttctttttt tgctttattt ttcaaaaaaa caattcattt catgttcata aacccataac
    44881 aatatctatg ttcagttaaa ctatatggat aaagttatgt tacaataaaa ttaatgaagg
    44941 agtgattttt ttgaaaatag gatacgcccg ggtatctact ggtttacaaa atttggattt
    45001 acaagaagac agcctaaata aatttggttg tgaaaaaatt tttactgatc atatgagtgg
    45061 ggcaaaaagt aatcgaccag gattagaaat ggccattgat tttgttcgct ctggcgatac
    45121 acttgtcgtt tggcgcttag atcgtttagg tagaaatatg gaagatttga tttcaatcgt
    45181 caatcgactg aatgagcgtg gtgtgagttt tcatagtatt caagaaaata ttacgatgga
    45241 caaatcaagt tctacaggac agctcatgtt tcatttgttt gcggcatttg cagaatttga
    45301 gcgtaatttg atcctggaac gatccgcagc aggacgagca gctgctcgtg caagaggacg
    45361 gtttggtggt cgtcctgaaa aattgtctga acaagatttg gaattactga agactttagt
    45421 ggatagcggt acacctatta agactattgc ggaacggtgg aacgtctcaa gaaccaccat
    45481 ttatcgttat ttggcaaaaa tggaggagaa aaatggaaag acaaattctc attagttttt
    45541 gtcatttaat gctgaaaatt tttgccattt atctagaaaa gtgacaatag tatgagaatt
    45601 ttttgtaagt gtctactgat aacttattct caaatgttgt aaggatttta ttcatttgtt
    45661 aatattaa
//
LOCUS       DBBGRF010000021        40113 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000021 DBBGRF010000000
VERSION     DBBGRF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.021"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(104..1336)
                     /locus_tag="ACIZD4_001276"
     CDS             complement(104..1336)
                     /locus_tag="ACIZD4_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGC5990223.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1591..2160
                     /locus_tag="ACIZD4_001277"
     CDS             1591..2160
                     /locus_tag="ACIZD4_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5990224.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2338..2778)
                     /locus_tag="ACIZD4_001278"
     CDS             complement(2338..2778)
                     /locus_tag="ACIZD4_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGC5990225.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2936..3700
                     /gene="map"
                     /locus_tag="ACIZD4_001279"
     CDS             2936..3700
                     /gene="map"
                     /locus_tag="ACIZD4_001279"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HGC5990226.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3732..4655
                     /locus_tag="ACIZD4_001280"
     CDS             3732..4655
                     /locus_tag="ACIZD4_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGC5990227.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4731..5870
                     /locus_tag="ACIZD4_001281"
     CDS             4731..5870
                     /locus_tag="ACIZD4_001281"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HGC5990228.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5863..6663
                     /locus_tag="ACIZD4_001282"
     CDS             5863..6663
                     /locus_tag="ACIZD4_001282"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC5990229.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6663..7490
                     /locus_tag="ACIZD4_001283"
     CDS             6663..7490
                     /locus_tag="ACIZD4_001283"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC5990230.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7495..8202
                     /locus_tag="ACIZD4_001284"
     CDS             7495..8202
                     /locus_tag="ACIZD4_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC5990231.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            8302..9168
                     /gene="rfbA"
                     /locus_tag="ACIZD4_001285"
     CDS             8302..9168
                     /gene="rfbA"
                     /locus_tag="ACIZD4_001285"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGC5990232.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9182..9754
                     /gene="rfbC"
                     /locus_tag="ACIZD4_001286"
     CDS             9182..9754
                     /gene="rfbC"
                     /locus_tag="ACIZD4_001286"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HGC5990233.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9776..10804
                     /gene="rfbB"
                     /locus_tag="ACIZD4_001287"
     CDS             9776..10804
                     /gene="rfbB"
                     /locus_tag="ACIZD4_001287"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGC5990234.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10902..11753
                     /gene="rfbD"
                     /locus_tag="ACIZD4_001288"
     CDS             10902..11753
                     /gene="rfbD"
                     /locus_tag="ACIZD4_001288"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGC5990235.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11787..13820
                     /locus_tag="ACIZD4_001289"
     CDS             11787..13820
                     /locus_tag="ACIZD4_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990236.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13864..15144
                     /locus_tag="ACIZD4_001290"
     CDS             13864..15144
                     /locus_tag="ACIZD4_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HGC5990237.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            15354..16160
                     /locus_tag="ACIZD4_001291"
     CDS             15354..16160
                     /locus_tag="ACIZD4_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990238.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16172..17392
                     /locus_tag="ACIZD4_001292"
     CDS             16172..17392
                     /locus_tag="ACIZD4_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990239.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17382..18968
                     /locus_tag="ACIZD4_001293"
     CDS             17382..18968
                     /locus_tag="ACIZD4_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC5990240.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19007..21145
                     /locus_tag="ACIZD4_001294"
     CDS             19007..21145
                     /locus_tag="ACIZD4_001294"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC5990241.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21513..22496)
                     /locus_tag="ACIZD4_001295"
     CDS             complement(21513..22496)
                     /locus_tag="ACIZD4_001295"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC5990242.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            22874..24265
                     /locus_tag="ACIZD4_001296"
     CDS             22874..24265
                     /locus_tag="ACIZD4_001296"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGC5990243.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            24281..25321
                     /locus_tag="ACIZD4_001297"
     CDS             24281..25321
                     /locus_tag="ACIZD4_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC5990244.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            25340..26425
                     /locus_tag="ACIZD4_001298"
     CDS             25340..26425
                     /locus_tag="ACIZD4_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HGC5990245.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            26458..27420
                     /locus_tag="ACIZD4_001299"
     CDS             26458..27420
                     /locus_tag="ACIZD4_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HGC5990246.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            27413..28840
                     /locus_tag="ACIZD4_001300"
     CDS             27413..28840
                     /locus_tag="ACIZD4_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGC5990247.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            28842..29912
                     /locus_tag="ACIZD4_001301"
     CDS             28842..29912
                     /locus_tag="ACIZD4_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysialyltransferase family
                     glycosyltransferase"
                     /protein_id="HGC5990248.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            29899..31320
                     /locus_tag="ACIZD4_001302"
     CDS             29899..31320
                     /locus_tag="ACIZD4_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC5990249.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            31333..32340
                     /locus_tag="ACIZD4_001303"
     CDS             31333..32340
                     /locus_tag="ACIZD4_001303"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HGC5990250.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            32352..33356
                     /gene="neuB"
                     /locus_tag="ACIZD4_001304"
     CDS             32352..33356
                     /gene="neuB"
                     /locus_tag="ACIZD4_001304"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HGC5990251.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            33353..34501
                     /gene="neuC"
                     /locus_tag="ACIZD4_001305"
     CDS             33353..34501
                     /gene="neuC"
                     /locus_tag="ACIZD4_001305"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HGC5990252.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            34474..35151
                     /locus_tag="ACIZD4_001306"
     CDS             34474..35151
                     /locus_tag="ACIZD4_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HGC5990253.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            35102..36283
                     /locus_tag="ACIZD4_001307"
     CDS             35102..36283
                     /locus_tag="ACIZD4_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGC5990254.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            36296..37273
                     /locus_tag="ACIZD4_001308"
     CDS             36296..37273
                     /locus_tag="ACIZD4_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC5990255.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            37273..38181
                     /locus_tag="ACIZD4_001309"
     CDS             37273..38181
                     /locus_tag="ACIZD4_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HGC5990256.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            38182..38934
                     /locus_tag="ACIZD4_001310"
     CDS             38182..38934
                     /locus_tag="ACIZD4_001310"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HGC5990257.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            38939..39886
                     /locus_tag="ACIZD4_001311"
     CDS             38939..39886
                     /locus_tag="ACIZD4_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGC5990258.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT        13388 a         6107 c         7834 g        12784 t
ORIGIN      
        1 aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt agatccttta
       61 ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc caatcgccat
      121 ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc atcttgtcag
      181 atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct gctaattctt
      241 catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct agtgctaagt
      301 gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat tgagaaatag
      361 gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca tctgtatcaa
      421 gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaacaact tttccatctt
      481 taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc tttgtacttg
      541 aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc gtcggcatat
      601 ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa agatggtttt
      661 taggcaatcc gataatgata tctgtaccgg gagcagtata gtgaagggca gaaaattgtt
      721 ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc catgctaaga
      781 cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat gcctcaactt
      841 gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca gccgcagcca
      901 cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt agtgctttgc
      961 cattcgctga ttgataagac gctactcgat ggctatctac accagcaaat gcatcgggat
     1021 cggcagaaac aacgctgatc ctgcttgctc ctttttcaag ccattcatcc gcttgatcga
     1081 ttttagattg tggtacattc tcaatacgat ccgttgcagc atgtaaaaga aattctcttt
     1141 ggatctggtc gtcagtccat tgaacgataa cctcagcggc tcctagttta taagcttctt
     1201 gtgtgatcaa tcgagcaagg ggtgcctgtt ccacgctgat ctgtaaaaca actgtgtgtc
     1261 ctttttctgt ggctacgcca gtttctgcaa ttaagcgtgc atattttttt agaagttcat
     1321 taaaatcaga taacataata aaaattcctc ctcaccattt tttctggtaa ctattagcat
     1381 gataccattt aattatgatt caaacaatga ggctttaaat aaaaaaagga ggttattttt
     1441 ttaaggttaa gtttcatgat atatgttact acttgctatt tcagcttgtg aagaaaatca
     1501 aaaactaatt ttgcatatca aaaaaaacat gttacaatga aattaatcaa tggtggaagc
     1561 gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat tactagagaa
     1621 cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg atttactgcg
     1681 agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga gtttaaaaat
     1741 atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca atatgaagtg
     1801 ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta tatccatttt
     1861 gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg tggaggaaaa
     1921 gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga tccagcttat
     1981 gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat catagctact
     2041 gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca gattgaaaag
     2101 atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga aatcgattga
     2161 atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa taaggaaaag
     2221 ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca tgaatgcaat
     2281 gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc aagtatatta
     2341 aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt cttcttcagc
     2401 attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg caaaagcagc
     2461 atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag atccgcagac
     2521 accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt ctacgatctc
     2581 atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat ctgcctcctc
     2641 gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat ccagattttc
     2701 aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc tagcatatac
     2761 gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa ttatgaatta
     2821 taccaaaaca tcattgaaaa gaaaataaaa cctagagaca cctggggaat gtcatttggc
     2881 taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg aaaatatgat
     2941 tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt tattagcaga
     3001 tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg atattgaggt
     3061 atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg gctttgaagg
     3121 gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat tccctcgtaa
     3181 aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt tgaaaggcgg
     3241 catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga tcgaccgatt
     3301 gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag tagggaatcg
     3361 gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc tagcgatcgt
     3421 tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag cagttcctca
     3481 ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca cgatcgaacc
     3541 tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga ctgcgtatac
     3601 aagagacggc ggactttctt gccaatatga acatacattg gctattacta aagatggtcc
     3661 aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt caataggtac
     3721 gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg atgcgcttta
     3781 ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct gtcgtcgttg
     3841 cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat attttaccgt
     3901 ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt cctgagaccg
     3961 tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca ggaggcttgt
     4021 tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat gctttgcaaa
     4081 ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc gtccgtttct
     4141 tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact atcgttcttg
     4201 ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc gtgaacttta
     4261 tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt gtcatcatgt
     4321 tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc attccgggca
     4381 cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc tatgctaggt
     4441 attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta ctcatgcttt
     4501 ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca gttgttcaag
     4561 aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa tggttcaata
     4621 aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta ttgtaaattt
     4681 atatcagtaa tttataataa ttatgactct taattaaagt aggtgcccat atgcttgttt
     4741 cttttagtat ggttataaga ttttttctga caattttatt atcactgata ttaacacctg
     4801 tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa agaagaataa
     4861 ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt gttatatcga
     4921 ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc ttgattgctt
     4981 ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca cctaaacaaa
     5041 aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat atacgtattg
     5101 attccttcac gcttcctttt attggatata tccaactagg ctggcttagt tttcccgtaa
     5161 cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt ttggatgggc
     5221 tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga tattttttcc
     5281 tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca agtattatcg
     5341 gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca ggagctctat
     5401 tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg acttttgttt
     5461 catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt tttgctatca
     5521 ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat cttcatcacc
     5581 gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat gcgatggctt
     5641 tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga acgatcatat
     5701 tgattattgc catgttgttt gctgcaattt tattatttga attgattggt ctgatcaatg
     5761 agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag taccgtacgc
     5821 aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa caaattaaac
     5881 cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg gacactagat
     5941 aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt tgacaacaat
     6001 tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta catcgatatc
     6061 tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct gatagctagc
     6121 gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga gacagttaca
     6181 gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc taagattctt
     6241 aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt tgattacgtt
     6301 ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact ggctgtgttt
     6361 gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc aggtagtttt
     6421 atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg tttcttcatg
     6481 tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa gttattgtac
     6541 acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa tgcaaaactg
     6601 tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg gcgttttttc
     6661 tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc agtcaatctc
     6721 cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt attatttacg
     6781 ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc gtttatcatc
     6841 atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct caagcagatg
     6901 aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac gattattttg
     6961 aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg atgatttttt
     7021 ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt acagctcaag
     7081 cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca ggtgttgcct
     7141 ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct ttagattttt
     7201 tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag atccttcctg
     7261 tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt aatcgatacc
     7321 gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg catttatcca
     7381 gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc aaaaaccggc
     7441 atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga attcgtgcgt
     7501 tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt agatagtatt
     7561 ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc agtagatgat
     7621 acatgggata tattaactga atacgcagaa aaagataagc gaatccagct tttttcgggg
     7681 cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa aggagatcta
     7741 atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa gatcactgac
     7801 tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat tgtggacagc
     7861 gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga aggatggctt
     7921 aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc ttctttaaaa
     7981 cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat tggtttgctg
     8041 ggaggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag acatgattta
     8101 aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg gcgtgttcat
     8161 ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat gtttaaatcc
     8221 ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga aatttgaaat
     8281 caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag cggaacacgt
     8341 ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga caaaccaatg
     8401 atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct gattatttca
     8461 acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga tttaggactg
     8521 cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt tatcattgga
     8581 gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat ttactatggt
     8641 ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc gacagtattt
     8701 ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga gaatatgcaa
     8761 gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt aactggcctt
     8821 tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc agaacgtgga
     8881 gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact atccgtagaa
     8941 cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt gcttgaagca
     9001 tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg tttggaagaa
     9061 attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc acagccattg
     9121 aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg agtccttaca
     9181 gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg acgtctttgg
     9241 cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag aacatggatt
     9301 gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg tccttcgggg
     9361 gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag tcactggagc
     9421 agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc aatgggacgg
     9481 atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat atgcccatgg
     9541 attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt actataatgc
     9601 agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt ggccaattga
     9661 tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa aagaatttga
     9721 agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt ttcttatgaa
     9781 aaacatcatt gttaccggag gtgccggatt catcggctct aatttcgttc attacgtggt
     9841 aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg caggaaacaa
     9901 agagaacttg gctggacttc ctagcgatcg cgtagaattg gtcgtaggag atgttgcaga
     9961 tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt acgcggcaga
    10021 atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga atatcattgg
    10081 tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc acgtatctac
    10141 tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg gggaaggcga
    10201 aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt cttctacaaa
    10261 agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac gtgcaaccat
    10321 ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta ttcctcgcca
    10381 agtaacgaat atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa agaatgttcg
    10441 tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga cgaaaggcag
    10501 aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga ccgtgatgga
    10561 attgatctta gaaatgatgg gtcaaccaaa agatgcgtac gaccatgtaa acgaccgtgc
    10621 aggacacgac ttgcgttatg caatcgattc gacaaaatta cgggaagagt taggatggaa
    10681 gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt acgaagaaca
    10741 tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca aaaatggaca
    10801 ataatacaga gaaaatgtca ctgtattaat ggaaaaacac atgtgaggca ggcgctcgcc
    10861 tgtctctttt ttaaaataaa aatcaaggag cggataatca tatgttttta ttaactggag
    10921 gaaatgggca actaggtaca gaattgcgcc atttattaga tgaaaaaaat ctgcaatatg
    10981 tttcaacaga tgcaaaagac ttggatatca cagatgccga gaaaacaatg gcttacatca
    11041 cagaattaaa acctgatgtt attttccatt gtgcagctta cacagcagta gataaagcag
    11101 aagaagaagc aaaagaatta gatgagaaga tcaatgttga tggtacaaga aatgtagcac
    11161 ttgcagcaaa agctgtgaat gctcaattcg tctatatcag tacagactat gttttcgatg
    11221 gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta aatgaatatg
    11281 gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac tattatatca
    11341 tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg atgcaacgcc
    11401 tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga ccaacttgga
    11461 cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca tttggtattt
    11521 atcatttgtc gaacgaaaat agctgttctt ggtatgaatt cgcaaaagaa atattgaaag
    11581 atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa gcaacacgtc
    11641 cgcagtattc agtcatgagc ctgaaaaaga cagaagagtt aggatttgtc ataccaactt
    11701 ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag taatttcctt
    11761 ttatcaaata gaatttggag catgatatgg aaaaacaaac aagaagtgca cgacgaaaag
    11821 aaaagccaaa agcgaaccag gcagattcga atttggtgct tgacctgttt ctaaaactcc
    11881 gctatcttat tggcgtttta gtcatcgtgg tcatcgttac ttttaattta aacggaagtt
    11941 cacttggtgt ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga
    12001 tttttggaca gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca cctttttacc
    12061 tctcacaagc tgaagaggac tttccgttgg tgaacgagga ttattcatta aacggacaaa
    12121 acatgatcat tgcgtataat tctcctgtaa aggatattac ggttatcgga aaaccattca
    12181 actggggatt ctttttcctc ggaagagatc gaggactttc cttttattgg gcgatgaaat
    12241 tagtcgtcat ggtcttgctt ggattcgaag tactgatgat attaacgaag agaaaaaaag
    12301 ctctatcgct aatcggtgca tttgcgctga cattttctcc agcagtccag tggtggttca
    12361 tgcaacatgt gggcgatttg attttcttta ctttgggact gatgactgct ttttatcatt
    12421 atttctacaa tcatgataaa aaatggctac gaacgttgat gatgcttttg gtggttattt
    12481 tcggtattgg gtttatttta gtgatttacc cagcccatca agtgatgctg gcgtacttgc
    12541 tgatttttta ttttgttggc ctgcttattt actatagcaa gaaagtttca tgggatctgt
    12601 tggatgtagt gttgattgga ggggcagttt tatttattgg cggagtcatg gttcatttct
    12661 ggctaacgtc aaaagacgca ttgttagctt ctttgaatac cttatatcca ggaaaacggg
    12721 taagtactgg aggaaagtgg acgattggcg aatttttttc tttccttaca aattggaaaa
    12781 ttccttttga agatatcaac tattcgaata actctgaagt ggccctgttc tatcactttt
    12841 ttccaactgt attcctagca agtccatttg tgttatttgg caaaaaagat agcgaacaaa
    12901 agttactggg acgtattttg atgatttttt gtctgttttc tatcttttgg attaccgttg
    12961 ggttgccaaa atggctagca gaaatcactc tgctgtctta tgttcctcca ttaagagcca
    13021 tccttacttt tagttttgcg gcttgtttat tatcgatctg gtttatcgct tatatttgga
    13081 gagaagatgt tattcctatt tggtataaat tcattttgtt ggcagtaaat gcatggtctt
    13141 atttctatgc gattacgcat tcgaaaatgg ataattattt ttcggatttt gaaaccatcg
    13201 cagttgctgt gttgggaaca gtgattttag cttttgcatt atttggctgg agacgcttgt
    13261 tttacctcgc ttttgccgcc ttagttatcg tatctggctt tttcgtcaat ccagtcgtag
    13321 aaggtacagg agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac
    13381 aagatcctgg taaagtttgg ttgtctgaag atgaattata taacttcacc ccaacattgg
    13441 gagtgaaatc cttcaataca gtacgctttt atccagatat agctgcatgg aagaaaatcg
    13501 atccgaaaga agaatacgag aagtattata atcggtatgc tcatacaaga gcttttatcg
    13561 ctaaggaaga tacaaagttc attttagatc gtccagatat gttttcggtc acgttgaatt
    13621 ttgaagacgc agaaaaatta gggatcgact atgtgatcag taaacgacca ttaactgatt
    13681 acaaccaatt atatgaagcg cagttcacgc agctatatgg accggataaa gacggttata
    13741 tgatttttaa agtagaatat ccggattatc cagatgtacc acaaacacaa actcaggaaa
    13801 atcagctagt cgtacagtaa taggctagct gagaataatc ctgaaatgtt agtagaaagg
    13861 agagtggaga taattcaagc aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc
    13921 ttgcttttgt tactgacgct agtctttttt gtttggacag cagggttagg ttttccagca
    13981 actttgttta tatataacaa tagttcatta cttatcgctt ttagtgtggc tattttgctc
    14041 attttaaatg tttataaagc aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc
    14101 cttttcattt tcttttctta ctttcgggaa ttaagaaatg agtctttatt tggagactta
    14161 ctgtttcctt tgattatttt attttgttta gtaattaaat ggatcgagtg gacaaaatgg
    14221 gatcgcggta tttatctgat tgtcttttcg gtcttcctcg gaatcacgtt atatcgtgta
    14281 tttacagaga tccaagtacc agaaggacaa agcatctggg ctccaggcaa ttcgctttct
    14341 gatatttgga tcaatacgaa tataatcgga agttctttga tgactcttgc tttattgatc
    14401 agtggatttg ccagttcttt tgaacgatgg tatgtacgaa tcatcggtgc agtagcagtt
    14461 gttgcagctt ttctcgggat ttgggtctgc caatctagag gtgcattagt cgcgttgatt
    14521 gtttttgcga tattggatct tttacctaaa tcgttgatgc gtgtcattcg tgcgccattt
    14581 attgcttaca cggttacgat tcttttagct ttgccgattt cttatctggc ggctgtctct
    14641 gaaaaagtca atttgtttac cggtcgagaa gatatttggc ataaattcta tcagacgcta
    14701 ggagaaaaat ctgaacaaat tttactagga atgaaaacat ttatcttcca acgaggaaac
    14761 caatttttag gaaaccacaa tagttataat tctattttga atatctatgg attgatagga
    14821 tttgggattg ctgctttgct gcttatcctt tttattggtc gcttaacgtt gaaagcagat
    14881 ttatccaacg ggcagatgac ttttatctgg gccttttttg cggtgatgat gcagtcattt
    14941 atggaggata cattgacttc atacccatgg gttccgatta tttatatcct gttggctatg
    15001 gccgttcatc gatatgatga accagaagtt gcggaggaat tctatgttat ggaagaggca
    15061 tatgacgata tgacttatga tgatacatct tatgaggaac aaccagatag cgctcattct
    15121 tccaggatcc aacgctatca ttgataggca caaaatacga gagaggctgt gacaaccgtc
    15181 gcagcctttt ttggtttatt gcaattgtct agcatcttct gtaaaataga aacgttagag
    15241 aaaatcttgt atcatagaaa attaagaaag aaataagaac gcagctcggt accaaaaata
    15301 tggtaaaatg gcacttgact gtaattcact gaaaatcgct tggaggaaca caaatgttta
    15361 aagatttgta tttatttatg aaggacattt atcagaacag aaaattattg ctacagtttt
    15421 cgatcaatga cttcaaatca agatatgcag gatcgttttt aggaatctta tgggcgttta
    15481 tcaatccgct atttactgta ttgatttatt ggctggtatt tggtgttgga ctgaaagcac
    15541 aaatgatcga tgcaaaatac ccatttatcg tatatttagt taccgggatg attccctggt
    15601 tcttcttctc agatgcattt gcatcaacta cggttgtttt tcgggaatat acttatttag
    15661 taaagaaagt cgtattcaat attcgtatct tgcccacgac gaaaatccta tccaatctgt
    15721 acacccactt attcttcatt ctgattggca tagctgtcgc gcttataaat ggtatatatc
    15781 cttcagcaat gtctttacag ctgatttatt atttattttg catgtgtgct ttcttgacag
    15841 gattgacttg gctgacggca tcgatccaac catttttacc tgatatcatg caattaatta
    15901 cgatcgtgct gcagttgatc atgtggacat taccgatatt atggagccct aatcagtttg
    15961 attcaggtct tgtaagcata ttgaaattaa atccgctgta ctatgttgtt caaggttatc
    16021 gtgagtcatt tttaagtgaa gcttggttct gggagcatgg aacatatact ttgtatttct
    16081 gggttttcac gttagtaatg ttcgtaatcg gctctgcagt gttccgtaga ttgaaaccac
    16141 atttttcaga tgtgctgtaa ggagaatagc tatgacagaa tatgcaatta gactaaaaga
    16201 tatcacaaaa tcttataata tgtacgcaaa accttcggat cgatttcgtg aagccctcaa
    16261 tccttttaag aaatcctatc atgatgtatt ttatgcgttg aaaaacgtga atgtagaaat
    16321 aaaaaaaggt gagatgatcg gtttcgtggg agaaaacgga tcgggaaaat ctacaatgtt
    16381 gaaaatcatt acgggagtac tgacaccaac atccggcacg atggaaatcg aaggaaaaat
    16441 ctcagctttg ctagaactag gatcaggatt caatcctgag tattctggct atgaaaatat
    16501 ctatttaaat ggaatggttc taggattttc aagagaagaa gtcgatgaaa tggtcgatga
    16561 tatcattgaa tttgctgaca tcggagacca tatttatcaa cctgtaaaaa cttattcaag
    16621 cgggatgttc gttcgtctag cttttgctgt agcaatcaat gtgaatcccg atattttgat
    16681 tgtggatgaa gcattggcag taggcgatct tgaatttcaa ctaaaatgta tggaaaaatt
    16741 tacagaaatc aagaactcgg gaaagacgat tttattcgtt tctcatgata tcagttcgat
    16801 tcgtcgtttt tgtgatcgtt cctattggtt gaaaaacgga gaagtcgtcg aatatggcga
    16861 tacgatggaa gtaacgacga attatgaaaa ctttttaaag aaaaaatcag ttaaaacagt
    16921 ggatcggaat aaaaaccaag tagaacggtt cgccgctcca gatatcgtcg acgtgacgaa
    16981 agcggaattg ttggataaag acaaaaatcc ggtggatatg ctggaacaag gagaaaaact
    17041 atacgttaaa gtaacttatg aagtaaaaga tgatacaatc aaaaatccgg ttttaggaat
    17101 tgcgctacga acagtcgaca atttttatgt atgcggactt aatactctac tagatggtat
    17161 caagattcct tggaaaaaag gagagaatat cttttatctg gagtatgaaa agttaggttt
    17221 gttagctggt gaatattatt ttgacgttgc ggtctttgaa gaaaatgcaa cggttccttt
    17281 ggtatataag acaaagtaca tgaacttgtt tgtcagcggt tcttatatcg gagaaggcat
    17341 cgtggtctta gaccataaat gggaagaagg gactcatagc aatgaaatat gattttgaaa
    17401 tggacctaga tgaacaaagc agtgtgggaa aaattgccgc acagatcaaa ccaggaagta
    17461 aagttttaga gtttggtccc ggaaacggcc gattaacgaa acatttaatc ggagcaaaac
    17521 aatgtgaagt gagcattgtt gagttagata aggaattgtt cgattttgtc agcgaatttg
    17581 ctcaagatgg attttatggt gatatcgaaa gttttgagtg ggcaaactat tatgctggac
    17641 agacatttga ttacgtcttg tttgcggatg ttttagaaca tttggtagat cctggaaaaa
    17701 cattgaagaa agtcagagaa tttttgaatg aagaaggaga gatcctgatt acattcccta
    17761 acttggcgca taattctgtc atgatcgatt tgttcaataa ccaattgccg tgggcttctt
    17821 atggtctcct agatgaaacc cataattctt tttatactca tgatggcttc caaaaagttt
    17881 ttgaaaaagc gggattattc attaatattg aagattattt gtacttagct gtaggtgata
    17941 cagaattaaa atcaacttat gaagaattgc cggaagctgt acgctatgat ttcaaaatgc
    18001 gaccatttgg tgaagtctac caatactttt tctcattgat gaaacatcca gtagcacaaa
    18061 gttccattgc agagccacaa aattctaatt atgtaaaagt gttagaagta acccagcaaa
    18121 cgaaacaaga tgaaacaatc caacaaatac cattcaataa tttcacaggg gaaaatgaga
    18181 cactaagttt ccccgtatca gaaacaacag aaagaatggt gtttcgcttc gcgcaacaac
    18241 ctagctttat cgaattcagc gcagaagctg ccggagaaaa actaacattt atcgattcga
    18301 atgctgtagt caaaacagta aatgattgtt atttgtttga tgggaaagaa ttaccagagt
    18361 tcgttctaac ggatatttct gggaaagaag tgactatcca ttgtcactat cgctttatcg
    18421 gggaattgac accaacaatg aaagaattgt tggaaacgat tcgtcccatg gctgaagtca
    18481 caaagcagct ttctgagaaa aatgacgaat tagaaagaga aaatcatcat cttcttgagg
    18541 aaaatacaag actagaccat acgttaaaaa caaccacaaa tcgctattgc acattgttgg
    18601 aaagtgatga atggacaata aaacatagac taggacgacg taagaaagaa acttcgaaaa
    18661 aaatccaaga aaaagaactt tctatatgta ttgacgagaa aatctgggat gcagaaacaa
    18721 aaatattaaa aatcatcgga tggggaatcg ctaattcgga tcgccagccc ttgtcctata
    18781 agttatcagc tgaccaatcg ccatttttcg aagcaattcc tgtttcacga gaagaagtca
    18841 atcaagcaga acagctcgca aaaggaacag aagcgggatt tgagttacga atcctttgcg
    18901 agcaagaacg ttcattctta gtggaagcag tagctcaaaa tggccaatca tggatcattg
    18961 aaatgtaaat aatgattaac ttataaagat aaggagtaaa cgaatcgtgc aaaaaaaaga
    19021 aattgccgta tttatcgatc aaatcactcg tgaacgggcc actggcgatt tgcttattgt
    19081 gggctgggca attgatgaag tgaccaaaga aatccctacg ataaaggtag aaaaagaaaa
    19141 tgtgattgct gaagcaacac atgtcgtaag attggatatc aatcatttat ataatcttga
    19201 tgttaagacc caaagcggtt ttaaggtacg tttatcaggg aaaatgagag gaaaagccat
    19261 cttagacttc caaacagcga gacatcaaaa tggcatagct gtgaaattaa acggtaaata
    19321 cccttatgat gacggcattg aatcttcatg ggaaagaaaa aaaagattac tgaaaaaagg
    19381 gataaattat gcaaggactc atggcgtaaa aaaagcgatc cgtcgggtca aattggaatt
    19441 gaagccagga tcgatcgact atgcagagtg gatcagtcgt catgagaaac cagatttgaa
    19501 agagcaaagg aaagaagcac aaggatttgc gtaccgtcca ttgatttcca tacttatgcc
    19561 tgtctataac gttgaaatca aatggctcga aaaatgcatt gattcggtac tggatcaaac
    19621 gtatgatcat tgggaactat gtatcagtga tgatgcttct actgatccag ctatccgaaa
    19681 gtgtctggaa tcctatcaag caaaagatga tagaatcaaa gtcgttttcc gaaaagaaaa
    19741 tggacacatc agtctggcaa ctaattctgc attggaaata gcagaaggag aatttatagc
    19801 actcttagat aatgatgatg aattaccgcc atttgcatta tatgaagtgg caaaagtgct
    19861 aaacgtacat ccagaactgg atgtgatcta cagtgacgaa gataaaatcg atgcagatgg
    19921 caatcgcttt gatccgcatt tcaaagcaga ctggtcgcct gatacattga tgggaaataa
    19981 ttatatctct cacttaggcg tatatcgaac aagcattgtt aaagaacttg gcggtttccg
    20041 taaaggctat gaaggttctc aagattatga tttggtcctt cgtgtgacag aacaaatccc
    20101 tgcagatcat atttaccaca ttgaccgagt cttgtatcat tggcggacga tcccaggatc
    20161 aactgcaagt aatggcgaag ccaaaagtta tatctatgat tccggagtga aagcattgac
    20221 agatgccctg tctagaagaa acatcaaagg aagcgtacgt cctggcagaa tttctggatt
    20281 ttatgagatt gcttatgacg tcttgcaaga ggatttggtc agtgtgatca ttccaacgaa
    20341 gaatggctat gaagatctaa aaacttgtgt ggattcgatc atcgaaaaaa cgtcttattc
    20401 aaattatgaa atcattattg cggataacgg aagtacagat ccaaaaatgc aagaattatt
    20461 tgcagaatac aagcatcagc tgaaagaccg ctttatcgta gaattgattg acattccatt
    20521 caattattct cgaattaaca atttagcagc agaaaaagca aacggcaaat actttttatt
    20581 cttgaataac gatacagaag tgattgagcc agattggatg acggtgatgg tttcttatgc
    20641 acagtttgat cgaatcggct gtgtaggagc aaaactgttt tatccagatg atacaacgca
    20701 gcatgcagga gtattattag gaatcggtgg tgttgcaggg catgcattga ataactatga
    20761 tcgaacacat tgtggttatt tcggccgatt ggtcattgac gtcaattact tagcagtcac
    20821 tgcagcttgt atgatggtca aggcagctga cttcaatgct gttaacgggt ttgatgaaac
    20881 attagaagta gcattcaacg atgttgactt gtgcttgaaa gtttatgaac tgggtcgtta
    20941 caatgtctat gcacatcaag cagaattgta ccatttcgaa tctaaatcaa gaggttatga
    21001 agatactcca gaaaaacaaa gacgttttgc tggtgaaatc aaaaaaatgc aagataaatg
    21061 gccagcatat attgcgcatg atccatttta caatgataat ttaacaaaag aaggaatcgg
    21121 cgacttttcg ttgagaccag attaaactat aataaaaagc tgttatgttg tgattcgctc
    21181 gcacataacg gctttttata gttttttgtc aaaaaaaggc agaaggtgcc gactcaaaaa
    21241 aataagtcga ggttgggaca gaagtgttta actccgagaa ataagaagaa attcacgaaa
    21301 attgcttttc aaatttttgt gaatttcggc ttatttaaga agaagttgct tctgctccca
    21361 ccgtttattc gtttttaaag aatgagacaa aagtgtttct tacttttgtc ccacgctctt
    21421 attcatgctc agagcgccaa tagatacaaa atcatagcca aagtttcacg aaccctagct
    21481 gtcaaagaat cgatatttta ttttaatata ggctatttta aaataaatgg tttaaggtat
    21541 tcctctacaa aagccactct atcaattatc atgggtttaa aataagaagt gatggagata
    21601 accagattgt tcttagcgtc aatataaaga acatttccac tattaccaat tgctgaatat
    21661 atttcgttct cagaatctaa tacccaccat aaatagccat atctcatatt ttgtaagtct
    21721 tctaaagcac tggttctagg tttgaacatc tcgtttatcc acatgggtgg tacgatttgt
    21781 tttcctttat acatcccttt atttaggcat aatacaccaa tttttgccag atcacttgcc
    21841 gataaacaca aaccatatcc tgccgtcccg atatttagtg gatcacaaaa ccagacattg
    21901 gttttaggag acttatccat tgtaaactgc ttatgttctt cagctgtttc agcataataa
    21961 ttgacatggt ttggtatccc tataggatca aatagatact tattggcaaa atcaacagtt
    22021 gttagcttac ttgtctgata caacaagcca gttaatatgt gtaaacagac agtttgatag
    22081 ttgaattcgc cggttatacc ttttcttcct cccaataaat ctagtgatgt ttttgtccaa
    22141 tcttcacttg aacagacttt tgtccatgga tcgcctttac atttgtaggg tgctttcatt
    22201 gttagcaagt gcttgattgt aatagcgtaa atagttttct ccccgcgttt cactttatac
    22261 tctggaaaat aatctaatac tttatcatcg atacttttga ttaatccttg ctctaaagca
    22321 atgccaatca gcaaagatac aatacttttc gttgctgaca tgatatgaca agtatcgtct
    22381 tttttataac cattccattc atctgtataa acttctaccc catccttata tgcgacaatt
    22441 tgacatatat ttggttgtcg aaaaccaata aaatcatgca actcttgttt attcataaga
    22501 tattacctca ctttcttcta taagcataat gtcattaaaa atcgatttca attttttcga
    22561 ttcttcacgt aatacaggta ttcttatgga ctagacagcg ctttgggaag atggattctc
    22621 tgaaaaatat aaaggttcac tttatgagtg gataaaaaaa gcagcaaata cttcgacttc
    22681 tttaatttac caacattagt gaaaatcgat tcatctggag atttgtaatt tagagtcctt
    22741 gtcttgatta gaggtgtata aagcttttta ttagacattt ttaaattcca ttacaatttg
    22801 cttataaact aggtttttaa aggtgactat ggtaagataa tagagatatt attttgtgat
    22861 taggagtgta tatatgaata aaaatggaga atggagtgct gcacgacgga tattcattat
    22921 attaatggat gttattgtat acaatgcagc aatatatagt agtttcttac tgaagtttcg
    22981 tggagagatc ccattacgaa atttagaaac tttccaacac tcagcaatta ttatttcagt
    23041 gatttttatt gcgttgaaca ttttgttggg tgcatatgtt ttttataatc gaatgatcag
    23101 tgacatcgtg tttgtcacag tcatcggtca ggtattgatg acactaggga tcatggtagt
    23161 gacttttgcg ggccgctggt ttgcttttcc acgtcttgtt atcttacttt catttgttct
    23221 cggtacgctt ttcttaagta tctatcgtat tctcgtatat aaactttatt tacgcgtaag
    23281 tcgagataaa aaggtcgtca ttattgggtt agaaaaggat gtcgcaccag caatccaaaa
    23341 ttttggttca aagaaaaaca acaaacataa agtcgaagca gtcattcttg ataactatta
    23401 tgcaaacatc aaaaatatga ttaaagacat cgatattgtc tatcttgctt ctcatatcga
    23461 agaaactgaa aaaatcaaaa tctatcaatt agttactaaa aatgaaaaaa aattgttttt
    23521 gaatacaaca tttgaaaact tgacattgat caatccaaat attatgaatt tcgaagatga
    23581 aagtattatt gaagcatctg gatttagaat ccaacctgaa tatgaactat tcaaacgttt
    23641 gtttgatatc atcgtttcac ttgttttatt agttattgct tcaccattta tgttattcac
    23701 agcaatttta gtcaaagtga catcaccggg accaatcatc tataaacaag tgcggatcac
    23761 aaaaaatcaa aaggaatttt caatctataa attccgctcg atgaccgcca cagccgaagc
    23821 aaaatctgga ccagttttag ctaagagcaa tgatgcacga gtaacgcctg taggtaaatt
    23881 tattcgagct gtccgctttg atgaattacc acaaatcttc aatgtgctga aaggcgatat
    23941 gtcgatcgta ggaccacgtc ctgaacgtcc tttcttcgtc gatcagttca atgcagaaaa
    24001 cccttattac tacttacggc ataatgttcg tgctggtatc actgggtatg cacaagtcta
    24061 tggaaaatat gtctctgatt acaacagtaa attacgtttt gatttacttt atatcaaaaa
    24121 atattcattg atgcttgatt taaagatctt gctgcaaacc atcaagatcc tatttgataa
    24181 aatgtcctct caaggacttg aagaagacga aaatgtgatc tcattggcag aaattgcttt
    24241 tccgaatgaa aaaatctttc gctagttggg aggcgtaaaa atgaacaatc cgaaattcag
    24301 cataatcgta ccagtataca atgcagaagc aactattggt cgaacgattg atattctaaa
    24361 agaattggat tatgaagagt acgaagtcgt tttagtaaat gatggatcaa cagatcaaac
    24421 acaggaaatc attcaagaac tgattgaaaa tgatgaacgt tttgaattga ttactacgac
    24481 caatcaaggg cccggattag caagaaacga aggaataaga cagtcaaaag gagaatatct
    24541 cttattcttc gatgcagatg acacgccagt aaaaacgatc ttgtcagatt atgatcattt
    24601 gctagaaaag agtccaaaag cggatcttgt tgttagttcg tttgtttttc gtacaatgga
    24661 cgagggaaga atcgtttccg aaaaagaaaa cttagttaca gaatgtcact atctaactca
    24721 cgaagagttt ataaaagaca tgtatcagtt aatgaatgaa cagttgatgt atgttgtatg
    24781 gaacaaatgc tatcgtagcg atattctgaa aaataaccaa attctattta aaacttataa
    24841 tagttgtgag gatcgaatat ttaacttaca ttattatgaa tactgtcatc aagtgatcat
    24901 gaacccaaaa gtagaatata tttatgaatt tgaaggtggg aaggggatca ctaatcaata
    24961 ccgacctaac aagttcgaaa catttaaaga attctattca ttagcaaata ctgtaacaga
    25021 cgatattaat aaagacggta tggcggcgct tcttttaaaa gggacaactt cagttatttt
    25081 ttctatttat agtacctctg caagaacttc aaaagagaag aaagacgaag caaagcagat
    25141 attgagtgat ccagtgatcc gagaagccaa gcaaattgct aagacggatt cttcagcaaa
    25201 aaaaataaca aagttgcttt acaatatgcc agctccacta tttttatctg ctgtaaaagt
    25261 tggaagcttc gttgaagtga aaatgccagg gttaatggct gctttgaagc gagtatatta
    25321 gttaatggag gaaaatataa tgaaaagaat tttgcatttt cagggacgaa tgggtttagg
    25381 tggagcagag tctttcatga tgaatttata tcgtaaaatt gatcgtacaa actatcaatt
    25441 tgattttttg atttatgaag attatgcaga tgttcaagac tatcattcag agattgaaag
    25501 attaggaggc cgtatttttg ttgtacctaa tcctaagaaa aatattttta aatatttaat
    25561 agaagtgaat aagttactaa aaaaagaatc tttttctata gttcacaatc aggtttattt
    25621 tggcggggga attaatttat ggttagccaa aaagaatgga atcagacaga gaattgctca
    25681 tagccatgca actgaagatg gaaaatctca aaatattgta atgaatgtat tgcgtaaatt
    25741 tttaaccaaa ttgttgttac aaaatgcaac agactacctt gccgttagtc aagaagctgg
    25801 tgaaagtctg tttcaaaacc acccctttga gatagttcat aatggtattg atttagagct
    25861 ttatagtaaa aattcagaag ctaaggttaa taagagaaaa gaattggata tctcaatgag
    25921 tacttttgtt gtgggaaaca ttggacgatt agagaaacaa aaaaatcaat cttatttgtt
    25981 agagattttt ttagaaatac taaaaatgaa ttctgattct tacttgattt tagtaggtga
    26041 agggtcactt agaaataaac tgaaagccaa agcagtagaa ttggatatag agaaaagagt
    26101 aaaattttta ggagaaagaa acgatattcc cgagttatta tctgtgatgg atgtttttgt
    26161 aatgccttct ctttatgaag gtctgccaat ggttggatta gaagcacaag cagcaaaatt
    26221 aaaattagtc ttagcagata ctatttccaa agatacaaag ttaacaaata atgtggattt
    26281 tgtatcatta gatgaaacac cacaagaatg ggcaaaaaaa gtaataaaag agccgtatgc
    26341 taataaaata acacaagaac taaagagtta tgatgtttcg tacactactg aacaaatgga
    26401 gagtatatat agtagagatc attaaaaatg ttcaagatat tttaggagtg attatttttg
    26461 aaaatatgtt atttgatatt ggcatacaat gatattggca acttaaagag attggtcaat
    26521 cgattgaacg aaaatgcagt ttttattatt catatagata aaaaaactga tatagaacca
    26581 tttattgaag catttaaatc atatgataat gttgaatttt tatgtaataa aaaccgtgtt
    26641 aaaatttatt ggggtggttt ttccattgta caagcagaaa tcaatttagt aaagagagca
    26701 ttacaaaatg agaaatattt aaaatatgta ttattatctg gtgctgatta tccaatcaaa
    26761 gataatgagt atatttataa ttattttaaa aagaatagtt cagtggagtt tattcgtgga
    26821 atagatctag atcaaattaa acataaagaa ttttattata aacatataga tgtatatcaa
    26881 aaacatgatt atcctagaat taataggaat aacacaactg catttaaaat ttttagagct
    26941 ataattaatc gttgtctgag gatgattaaa cttcccccaa aaattagaca ccataaattt
    27001 gatttgtatc atggttctca atggtgggct ttgtcgaaag aatgcctaac agaattaata
    27061 caaatgtatg aacaaaatca acaagactac ctgaatttta aaataggtat gtttgcccca
    27121 gatgaaaaat tttttcatac actttttttt aattcctcgt tcaaaaataa aaatgttatt
    27181 ggaggaccag atttaccact tgaattgaaa aatattgaag aaactacttt acaaacttcg
    27241 aaattagcaa atattcatat tattgatcct tccatgaaca aatggtttga tgaaagggat
    27301 atagatcaaa taaaagaaag tgaaaaatta tttgtaagaa aagttaaatc ggattactct
    27361 gataaactat taaatagaat tgataaagaa attttgaaag ttggaaatat agatgaatag
    27421 aatagtacct gttttagaga agagtttatt aagtcgagat gcgtttcgag taataaattt
    27481 aatcatttgt ctgctttatt ttatgcctag tacttttaat gtaactaata tcccgatgaa
    27541 aatagctttt gcttggggtg gaattatagt tttgtatgag gtttttataa agaaaaattt
    27601 ttttaaaatg cgtttttctt ggctactgat tggagcaatg attagtttta tcttaactat
    27661 aatcattaac agagaaaatt ttttaattcc atctatttat aattttggat atttgctgat
    27721 tactttgata gtaatttttc ctgcagactt ttcacaaagt gaagaggaaa aaaagaaaaa
    27781 aatggtgtat tttaataatg ttttcattat cataattttt ttagctgcgc taatatctat
    27841 ctatcaattt atttttttga tttcttatca tgtcccaaca ggaacgccag gattacttgc
    27901 aagacaaggt tttattgaac atcggttatt tggtgtctat acaagtccaa atgttggagc
    27961 tatgtttgga tatacttcta ttattttaag tttaattagt gtattaattt caaaaataac
    28021 aaaaacgatt cgtgtttttt atatgatgaa ttttatcgta caaatatttt atattacact
    28081 ttcttcgtct agaggtgccc aggtagtaat ttgttctttt ttagtattat ttcttttgtt
    28141 gtttgccaat tcaaaattta gaaagagcat tagagaagta ctacctgtaa aaatcaaatg
    28201 gatggtaagc atattattag ttctattggt atatttttct tttggtacta attatgctaa
    28261 ggatttttta gcaacaattc ctgtatcgat tgatagaaaa gtagaagtta tagagtcaaa
    28321 tgaatcagat aaaactccac ttccagaaaa agaagtaata ttacagcatt ctagtgataa
    28381 ctccgaaatt tcagctggtc gttttacgat ttggaaagct gcgcttaaag ttataagacc
    28441 aactttgtta tttggttatg gagagaccga tttctatggg aatagcgatg caaaattttt
    28501 gaaaaaagta gatcttgata ctacagatgt gaatgaacta aaaagagcac atggaaacat
    28561 gcataatgga tttcttcaag tacttgtatc aagtggtata attgctttta tatgtatcta
    28621 tgctttctat gtgttaaata tctttagttt actcaaaaca ttttttagaa gtaaagtgaa
    28681 ttatgcgttt cttggtattg ttttaatttt tatactatct atttttatag atgaaatggt
    28741 ggaggctcat gtacttttca ataagcgcga tgtcatttca attgttttct ggtattattt
    28801 gggaagcatt tcttacttgt atttaaaaaa ggagaattaa tatgaagaca gctttcattg
    28861 cttggactcc tttacatttg attaatatat taaatgttta tcaaaatttt taccgagaat
    28921 caaaaggaga tttatttatt tattctgaat ttgaaaacgc tagaagatat agtgagcgta
    28981 taaaagaatt agggctattt aatgatgttg tttttgtgaa tcaccggaaa atcggttctt
    29041 cctttaaacg taaaattaac ttgttaacta accataatca atttttctcg gatgatttat
    29101 ccgtttatga tgaaattttt atacaggggg aaaattattt cacaaaaata cttttctcca
    29161 atgtttacaa aaaaaatcca gatgtaaaac taaattatat agaagatggt ttgggtactt
    29221 atttgaagaa gagtatattt tcaacaagta aaaacgttca aagagttttt aaaatattaa
    29281 ataaaaatag catcttcaaa aaaaaaattg acgattattt tgtctattgt ccggaattgt
    29341 tactttatga tgtaaaaaat ataaaaaaaa ttcccaaaat agatgaaaac agtaaattga
    29401 tgaaaaacat acaatcaatc tttgggatag aagaagtttt tgtcggagat aaatgtatct
    29461 tttttgatca acctttatta tctgatggtt atggcataga tgaaacagat attttcgcta
    29521 aagtaaatag tatattttct ggaaaaaaag aaactttaat taagcttcat cctagagcaa
    29581 ggacaaatcg ttatggtgaa aaaaacatat tgaattccag tttaccgttt gaagtcttgc
    29641 tacttgaaaa tgacttctct tcaacacttt tgattagtcc tatatctaca atttcttttt
    29701 caccatctat gatgtttgaa aagacgatca actctattat gttggctaaa ttaattttaa
    29761 atgaatatac agcattatct gaagataaaa aagaaacatt gacaaatatt gttcttttct
    29821 gtgaacatta taaccgtcta tcagaagaaa aaattttact cccagaaaac tgggcagaat
    29881 taagaaagtt ggtagagtat gggattattt aacacacttt ccaagtcaaa attagttaag
    29941 tccagtttct ggtatactat agggaatttt tttattaagg gaatttcatt cataactatt
    30001 cctatttttg taaatattac tactcaagca gaatatggtt tgattaataa tttcacttca
    30061 tttgtatcaa ttttttcgat tcttgttggg ctaagcctaa attcggcaat taataatgca
    30121 agttttgact ataaagatga cataaatgaa tttatgtcat cggtactttc tctagctaca
    30181 ctttcgttaa ttgtgttctt attaataggg aacatatatt ttttgttttc aaatgctttt
    30241 tttgatatga accaacttgt atttaatttg atgttattac aaagttttgc tagttttgta
    30301 attagttata tccagtctta ttttacgatt aactttaacc attttaaata tttgatttta
    30361 tcttttatat ctactttttt gaatattgca atctctgtag ctttgatgca gacattatat
    30421 tttgatgata aatatgttgg cagagtagtc ggcggaacac tgtcatttgt gttgataggt
    30481 ttagtaattt atttaagaat aatgataaag ggtgctcatt tttttgataa aaaacagtgg
    30541 agatacgctt taaaaatctc tttgccgcta atcccacatt ccttagcaaa tatagtttta
    30601 gcacaattcg atagaattat gattaattct tatttaggtc ctgctgcggg gggaatatat
    30661 tcctacatta gtaacatagg tattattcta agcgtaatat ggatgtctac taataacgcc
    30721 tgggttccat ggttctatgg tgagatgagt aaaaataatg aaaaaaaagt gaagaaagtt
    30781 agtaactatt atttagtagt ctttactttg attacgatga ttgtaatggt agtttcgatt
    30841 gatttagcaa aatttatggc tccgaaagac tattattctg ggttatcttt agtggttccg
    30901 ataaccttag gctatttctt tcagttttta tatagtttac cagttaatgc tgaattttat
    30961 gagaaaaaaa catcgtttat tgcgattggt acagtagcaa gtgctatagt taatatacta
    31021 ttaaacatga ttttcatacc taggttagga ataattgctg ctggatacac aaccgtattt
    31081 acgtattttt tactttttat ttttcattat aatatcgcta aaaaaattac gaataaacaa
    31141 ttatttgaca caaaaaaaat atgtatcata ataatttttg tatcaatttt ttctttgata
    31201 cttcatattt taatcaatca aatgttgatt cgttacgttt tgacatcatt attgataatt
    31261 agtttagtta tatatttttt aaagattaag aatcgaatta tagatgacta taattcatag
    31321 gaggagatat aagtgtttaa aggaaaaaca atattagtaa ctggcggaac tggttccatt
    31381 ggaagtgaaa ttgttcgtca gcttttaaaa tatgaaccaa aagctatcag aatttatagt
    31441 agaggtgaag aaaaacaatt ttatatgcaa caagagctct caaatcacac taatttgaga
    31501 tttttaattg gtgatatcag agactctcaa aggattgatt atgcatgtcg tgatgtggat
    31561 attatttttc atgctgccgc aatgaaacac gttccagcaa gtgaatataa tcctatggaa
    31621 gctgtaaaaa caaatgtgat gggaactcaa aatgtaatag atgcagcgat caaaaataat
    31681 gtaaaacatt ttgtaggtat cagtacagat aaagtagtga gtcctactaa caccatgggt
    31741 gcgacaaagt tattgagtga aaaattaata atagctgcca atcagtataa aggaaaaaca
    31801 gaaacaatat tttcttgtgt aaggtttgga aatgtcatgg ggtcaagtgg atctgttatt
    31861 cctcttttta gtaaacaaat aaaaaacaat aaagatatta ctttgacaga tgttgatatg
    31921 acacgattta tgatgtcaat accggatgct gcaagattag ttctgtctgc tgctatgaat
    31981 tcaaaatttg gagaaacata tgtcttaaaa atgccggcaa tcaatatttt aactttagct
    32041 caatcattaa taaaaatata taatgataca catgatgaaa aatatagagg tgaaataaaa
    32101 gttgtaggta tcaggccagg agaaaaatta tatgaagagc taatgactac agacgaaatt
    32161 gaacgctcat atgaaaatga taaaatgtat atcattccac cacactatca tgctactgac
    32221 gaactgtaca aagattatga aaaaattaaa atcactgcat actcttcaga tgcaacagaa
    32281 ttaatgagtg gacaggaatt tattagaatc gcaaaagaga ataatgtcgt gacttggtaa
    32341 ggagttttat gatgaaatca gaagtatatg taattgcaga aattggtgta aaccataatg
    32401 gaagtctaga tttagcttta gaaagtattg ataaagctaa agaatgtgga gctaacgcgg
    32461 ttaaatttca aacatttaaa acgaataagc tagtttccaa aaaggctcca atggcaaaat
    32521 atcagaagga taatcttaaa gaggacagtt ctcaatttga aatgctaaaa aaattagaat
    32581 tatctcaatc tgattttatt agaataaaag attattgtat acaaaataaa attgattttt
    32641 tgtctactcc ttttgatgaa gaaagtgcag actttctaaa acaaattggt gtacaaggat
    32701 ttaaaattgg ctcaggagat ttaacaaatt taccttttct tagaaaaata gatatgtatg
    32761 ggttgccagt tttattatct acaggtatgg ctgatattca tgaggtcagt gaggctgtag
    32821 attgtttcat agatagtcca gttactattt tacattgtac ttcaaattat ccggctagtt
    32881 ctgaagatat taatttattg gcgattaaca cattaaaaga aatgttcggg atacccgttg
    32941 ggtactccga tcattcattg ggatatgatg ttggtatttg tgctgttgcg atgggtgcta
    33001 aggtaattga gaaacatttt accttggata aggaactacc tggtccagat cataaagctt
    33061 ctttagatcc tcaggaattt gcagattttg taaagcatat tagaaacact gaaatatttt
    33121 taggtgatgg tgttaagcga gcaatgcctt ctgaacttag tacaaaagaa gtatcaagaa
    33181 aaagcctagt ggtcactgag aatttaaatg tgggagatat tcttacagag aaatctctta
    33241 caataaaacg tcctggaaat ggaatagctc ctaagttttt atatcaatat attggcaaaa
    33301 aagttaaaag accaataagt gcagatagtg ttctgcttga ggaagatgtt gaatgaaaaa
    33361 aatacttata gtaagtggaa cacgagctga ttatggaata tataaacctg ttgctgagaa
    33421 tttactacaa gataattggg atgtatcatt tgttgtttct ggaatgcatt tatcccataa
    33481 atatggattt actaaagaat tgatcttagc tgacggattt agaattagtg gagaagttca
    33541 aagtttgttt ttagagaaca ataagggaaa catggctcgg tctgtggcat tagagataaa
    33601 tggtttcaca aatatatttg aacaaactag ccctgatttt gtattattac taggggatag
    33661 aggagaaatg ttggcagctg cgatagcttg tttgtatctt ggaatcaaaa cagcacatat
    33721 tcacggaggc gaagtgtctg gtactgtaga tgaatcaata agacatgcca taacgaaaat
    33781 agcatctgtt cattttgctg ctacggaaaa aagcaaagag cgtttaataa aaatggggga
    33841 agattcttgg agagtttttc ccgtcggagc tcctagaata gatactattt taaataatag
    33901 attacctagt tttagagata taaaagaaaa atatcatcta aaatttgaaa agaaaaaata
    33961 cgttttgcaa gtatttcatc cagttgtaac cgaactagaa aatatagaaa aacaaatttt
    34021 agctttgatc aattcaatgg aacaacaatc tcaaccaatt atttgcattt tacctaatag
    34081 tgatgctggt agcgaaatta tcagaaaaat gtaccagaaa tatttaaaaa cggatattat
    34141 ttatattacg aatttagagc cggaggaata cctgactata ttaaaagagt gcaaatttat
    34201 gatcggaaat tcttcttctg ggataattga agctgcatca ttcaaaatac cagtaataaa
    34261 tttaggaacc agacaaaatg gacgagaaca atctaaaaat attataaatg caaatctaaa
    34321 tgaaaatgaa attgaaactg ctttgaataa aatacaagat cctcagttta taaaaagctt
    34381 gaaaaatgtt aagaacatct acggtgacgg caacagttct agaagaataa caaaaacatt
    34441 gaatcaaata ttgaatgatg gggaagatat taagtggatt caaaaacaaa tagcttatta
    34501 aaatatacta gtgatccata cattattatt ggggctggcg gacacgcaaa agtcattatt
    34561 gaaaccttaa gattagaaaa taagttaata tatggatttt ttgatgataa gcaaaataaa
    34621 atgcaagatc tgaaatatct tgggaaaata aacgaattga atagctgggc ggatagcaaa
    34681 aaaaaaatct ataaatttat tgtagctatt ggtgactgtg tagtaagaaa aaagattata
    34741 aaaaaattga atatgccaag tgagcaatat ggaatagctg ttcatccaag tgctatagtg
    34801 gcaaaagaaa tttcaattgg ttatggaact gttatttttg cgaatgctgt aattaaccca
    34861 gatgctgtaa ttggagagca tgctataata aacacaggta gcattgttga gcatgattgt
    34921 agaattaata actatgttca tttatctcca ggtgtatgct tagcgggtgg agtacatgta
    34981 ggtgtaggaa ctcaaatagg aattggttct caatgtatcc agatgaagaa aattggatct
    35041 tggtgtatga taggcgcagg gagcactatt gttaaggata ttccctcaca ttccttagct
    35101 tatggcaatc cagctaaaat taagaaagaa ggaattaatt ttgaattcta gaattttatt
    35161 atcaagtcct catatgggag gaacagaaga aaaatatgtt gctaaggctt ttaaagataa
    35221 ttggatagcg ccattaggtg aaaatgtgga taaatttgaa gaaagtatta caaaatatac
    35281 tggttctaag ggcggagctt ctgcgttaag ttcaggtaca gctgccatac atcttgcctt
    35341 aagactgctt aatgttggaa aaaacgatat tgtctttgct ccttcattta cttttatagc
    35401 tacagtaaat cctattttat atcaaggggc tgtaccagtg ttcattgact cagaacctaa
    35461 tacatggaat atgagccctg ttgcactaga gagcgcatta gaagaagctg aaagaaacaa
    35521 ccaattacct aaggcaatca tcgtagtgaa tttatatggt caaatggctg attatgaacg
    35581 aattttagct attgcaaacc aatttaatgt tccagtgata gaagatgcag cggaatcgtt
    35641 aggttctact tataagggaa tttcgtcagg cttatttggg acaattggga tctattcatt
    35701 taacggtaat aagatcatca caacctcagg tggaggagct ctagtgtcta gtgataaaaa
    35761 atatgttgag cattcaagat ttttagcaac acaagcaaga gatcaagcac cgtattatca
    35821 acatagcgaa ataggttata attaccgtct aagcaatatt tctgccggta tcggacgtgg
    35881 acaaatggaa gtattgaatg atagagtagc taaacgaaga gaaattttca atcgatataa
    35941 ggaagctttt tctggaattg atagaattga aatgatgcca gaagtggatg gcatggtgcc
    36001 aaatcgttgg ttgtctactt taacgatcaa tgattataat tctattgatc aagtagttaa
    36061 cgtaataaat aaactaaatg aaaaaaacat tgaaacaaga gctttgtgga aaccactaca
    36121 tttgcaacca gtatttcaag gggtaaaaat gtattaccat gataataatc ttagtgtgtc
    36181 agaaaagtta tttaatagcg gcttatgctt accttctgga agtaatatga cagatagtga
    36241 acaagaattt gttattgatg agtttaaaaa aatattcaag taggtgtgat attttatgaa
    36301 cataggaatt attggtttag gttccatggg gaaaagaaga cttagactca ttcaagaaca
    36361 ctttaatgat attttactat gtggtgttga tactaatgag gcgagacgaa aggaagttga
    36421 aaaggaattt ggaataccaa cttataatag tctaacagag gcaaaaaatt tgtttgaaat
    36481 aaattcagtt tttgtttgta catcccctat aacccatgaa tttattataa aagaggcttt
    36541 aaatttagat tgtaatatct ttacggaaat caatttatta aatgaatatt atgatgaaat
    36601 aatcgaagta gctaaaaaga aagatagatt actttatcta tcttctacat ttttgaagag
    36661 aaaagaaatt caatatatta agtctaaagt gacgcataat aaaaaaattt cttatcaata
    36721 ccatgtagga cagtatttac ccgactggca tccttgggaa gattatcgca atttttttgt
    36781 ttcaaacaaa aaaactaatg ggtgtagaga aatattcgct attgaattac cttggattat
    36841 agatacattt gggaaagtta aatcgtttac tgtaatgacc cagaaattat ccaatcttga
    36901 tattgattat tcggacagtt tcactcttat tattgagcat gaaactggta tagttggaac
    36961 tttaagtgta gatgttgttt caagagtagc taaaagaaat ttaactataa ttggtgaaaa
    37021 gattttaata gaatgggaag gtaacccgga ttctctattt tcatggaatg aagaaacttc
    37081 tagtatgaca gatattcaat tgtacgatga ggttatgcat gataataatt attcacatac
    37141 tattattgaa gatgcatatt tagaggagat taaagaattt ttcacgcttt tggaaaagaa
    37201 aatggaaccc caatatactt ttgaaaaaga taagtatatt attaacttaa ttaacgacat
    37261 tgaggtaaat taatgatgaa agtaattttt tttgggttag ggtcaattgg aaagagacat
    37321 ctaaaaaatc taataagcta tggaaaaaag aattctatta attttgatat aacagcttat
    37381 agtagcagtg gaaaaaaaga gtttgaagaa ataacgtata ttcaaaatag agacgatttg
    37441 gatacacatt atgatatagc ttttattaca aatccgactt ttaagcatct ggaaacacta
    37501 aatgtaattg ttgaaaaagt tgattacata tttttagaaa aacctgcttt ttctgagagt
    37561 attgatctta ctcaatataa ttatgattac aaaaatattt atgttgctgc tccactgagg
    37621 tataaaaata tcatggaagt tgttcgtaat agtattcaaa gtaaaaaagt atattctgta
    37681 agagctattt gttctactta tcttcctgat tggagaaaag gtactgatta tagaaataat
    37741 tattctgcct ttaaatctat ggggggagga gtagaattag actgtataca tgaattggat
    37801 tatattataa acctatttgg tttccctaaa tcagtaaaaa aacagtttgg taaatattcg
    37861 aatcttgaaa ttaacagtaa tgatttagca acatatatat tgagatacga tgataaaatt
    37921 atagaaattc atttagatta ttttggaaga gttcctacaa gaaaatttca attgtttact
    37981 ttagatgaat gtatcaatgt tgacttatta aataataaaa taagttttga agaaaacatt
    38041 gttaaagaaa tgcctgaatc tgctaatgat atgtatgaga aggagttgaa atatttcttt
    38101 gaaaacgtag taacaggcaa agaaaactgg aatgatttat atcatgcaaa cgaagtattg
    38161 aaaatagctg aggagaaata aatggaaatt ttatttacta tttgtggtag agctgggtct
    38221 aaggggttta aaaataaaaa tttgaaatat ttggcaggaa agcccctagt ccatttcgct
    38281 ttagcaatga tagatatcta tcaacaaaaa catcctgaac ataattgcac gacttgtttg
    38341 aatacggaca gtaatgagtt agtagaattg acgactaagt taaatccgtc tgtgaaaatt
    38401 gtagaacgta aacctgaatt agctacagat actgtaggga aaattgaagt gatacgtgat
    38461 tcattcttac aactagaaag agaagataat atatttgatt taattataga tttagatttg
    38521 acttcacctt tacgtgaagt ttctaatctt gaagaattaa tagatgaaca tctaaaaaat
    38581 ttagataaag acgtctactt ttcagttgtt tctgcaagac gtaatcccta ttttaatatg
    38641 gtaaaaagaa ttgaaaatga agttactata gttaataaat caagatacac atctaggcaa
    38701 cagacacctg aagtttttga aatgaatgcc tcaatgtatt cttttaaacc tgaatttcta
    38761 aaaaaaagta attatatttt tgatgggcaa tgtgggataa taaaaatgag agattatcta
    38821 attttagata ttgatagtga agaagatttt aaatggttag aatttttgtt tcctaaattt
    38881 ttagaagatt cttcggagct tcaagatatc tataattatt tatatcggag gtaaaaggat
    38941 gagctgttat cttatcaccg gtggggctgg cttcattggt tctaccttag ccaatcattt
    39001 aggagaagaa catgtggtaa tcgtcgtcga tgacttatca atgggaaaag tagaaaatct
    39061 tgatatgacg aaaaatatca cttttattga gggagatgtc gctgagaaat ccttgatgga
    39121 agagatcatg aaagctaata aatttgatta tatctttcat ttagcagcag ttgctagtgt
    39181 ggcagattca gttgcccgac cagtagaaac acatcgtgtg aattttgaaa gtgtattaat
    39241 gattttagaa ttgatccgca agtatcaacc tgatttaaaa cggatcgtgt ttagttcttc
    39301 agcggctgtt tatggggatg aaccgacttt accaaaaaaa gaagagtccg tgattcgccc
    39361 attgacgcct tatgcggttg ataaattcgc tgcagaacaa tatgtgctag attattgtca
    39421 tttatatgat gtacccggta gcgcagttcg ttttttcaat gtctatggtc caaatcaaaa
    39481 tccgaattct ccatacagtg gtgtgatttc tattctcgta gatcgctata agaaacaaat
    39541 cgtaggagaa gcaacttcat ttacattatt tggtgatgga agccagtcta gagactttgt
    39601 ttatatagat gatgtaatcc aagcattact tttagttgcg aatgaggaag ctgcactggg
    39661 gaaacaattc aatgttggaa cgggtaaagc aaccacactt ttggaattga ttcatgcaat
    39721 caatgaaatt ctcggtgtag aattgacact tgaatacaaa gaagagcgtt cgggtgatat
    39781 ccatgactct ctagcagata ttactaagat ccagtcaatt ggctatcaac cgaaatatgg
    39841 tattttaagt ggaatgacta attatttgaa aactgaaatc aattaaaaca tactaagata
    39901 agattagagg gtaaattcag gctctttgtc aataaggact gatgagtttt gtaaaatcaa
    39961 atctgggata gaagggctct ttgtcaaatg atgttggtaa agagaaatct tagaataatt
    40021 tggacagaac agaaagaaga aaacctcttt ctgttctgtt tatttggtta aaaatgtttt
    40081 gccatgacga atcataattc gtagtttgaa att
//
LOCUS       DBBGRF010000022        39261 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000022 DBBGRF010000000
VERSION     DBBGRF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.022"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..286
                     /locus_tag="ACIZD4_001312"
     CDS             <1..286
                     /locus_tag="ACIZD4_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990259.1"
                     /translation="KSFLKVISKKRNLIKTTQLLKKYPGLLHTSIQFPQLITMIHRFI
                     RMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVAMEKAN"
     gene            345..785
                     /locus_tag="ACIZD4_001313"
     CDS             345..785
                     /locus_tag="ACIZD4_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990260.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            797..1465
                     /locus_tag="ACIZD4_001314"
     CDS             797..1465
                     /locus_tag="ACIZD4_001314"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HGC5990261.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1529..2152
                     /locus_tag="ACIZD4_001315"
     CDS             1529..2152
                     /locus_tag="ACIZD4_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HGC5990262.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2208..2594
                     /locus_tag="ACIZD4_001316"
     CDS             2208..2594
                     /locus_tag="ACIZD4_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGC5990263.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            2807..4198
                     /locus_tag="ACIZD4_001317"
     CDS             2807..4198
                     /locus_tag="ACIZD4_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HGC5990264.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            4809..5177
                     /locus_tag="ACIZD4_001318"
     CDS             4809..5177
                     /locus_tag="ACIZD4_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HGC5990265.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5357..6298
                     /locus_tag="ACIZD4_001319"
     CDS             5357..6298
                     /locus_tag="ACIZD4_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGC5990266.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6367..7098
                     /locus_tag="ACIZD4_001320"
     CDS             6367..7098
                     /locus_tag="ACIZD4_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC5990267.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7242..9422
                     /locus_tag="ACIZD4_001321"
     CDS             7242..9422
                     /locus_tag="ACIZD4_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGC5990268.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9442..9924
                     /locus_tag="ACIZD4_001322"
     CDS             9442..9924
                     /locus_tag="ACIZD4_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGC5990269.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            9940..10701
                     /locus_tag="ACIZD4_001323"
     CDS             9940..10701
                     /locus_tag="ACIZD4_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HGC5990270.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            10832..12166
                     /gene="murC"
                     /locus_tag="ACIZD4_001324"
     CDS             10832..12166
                     /gene="murC"
                     /locus_tag="ACIZD4_001324"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGC5990271.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12473..12958
                     /locus_tag="ACIZD4_001325"
     CDS             12473..12958
                     /locus_tag="ACIZD4_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HGC5990272.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            12951..13634
                     /locus_tag="ACIZD4_001326"
     CDS             12951..13634
                     /locus_tag="ACIZD4_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HGC5990273.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            13760..16405
                     /gene="polA"
                     /locus_tag="ACIZD4_001327"
     CDS             13760..16405
                     /gene="polA"
                     /locus_tag="ACIZD4_001327"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGC5990274.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16450..17286
                     /gene="mutM"
                     /locus_tag="ACIZD4_001328"
     CDS             16450..17286
                     /gene="mutM"
                     /locus_tag="ACIZD4_001328"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGC5990275.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17250..17879
                     /gene="coaE"
                     /locus_tag="ACIZD4_001329"
     CDS             17250..17879
                     /gene="coaE"
                     /locus_tag="ACIZD4_001329"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGC5990276.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            17931..18263
                     /locus_tag="ACIZD4_001330"
     CDS             17931..18263
                     /locus_tag="ACIZD4_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGC5990277.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18575..19066
                     /gene="nrdR"
                     /locus_tag="ACIZD4_001331"
     CDS             18575..19066
                     /gene="nrdR"
                     /locus_tag="ACIZD4_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGC5990278.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19089..20462
                     /locus_tag="ACIZD4_001332"
     CDS             19089..20462
                     /locus_tag="ACIZD4_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGC5990279.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20462..21388
                     /gene="dnaI"
                     /locus_tag="ACIZD4_001333"
     CDS             20462..21388
                     /gene="dnaI"
                     /locus_tag="ACIZD4_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGC5990280.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21517..21957
                     /locus_tag="ACIZD4_001334"
     CDS             21517..21957
                     /locus_tag="ACIZD4_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HGC5990281.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22101..22802
                     /locus_tag="ACIZD4_001335"
     CDS             22101..22802
                     /locus_tag="ACIZD4_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGC5990282.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            22799..23920
                     /locus_tag="ACIZD4_001336"
     CDS             22799..23920
                     /locus_tag="ACIZD4_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGC5990283.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            23935..25167
                     /gene="pepT"
                     /locus_tag="ACIZD4_001337"
     CDS             23935..25167
                     /gene="pepT"
                     /locus_tag="ACIZD4_001337"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGC5990284.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25299..26207
                     /locus_tag="ACIZD4_001338"
     CDS             25299..26207
                     /locus_tag="ACIZD4_001338"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC5990285.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26242..26514
                     /locus_tag="ACIZD4_001339"
     CDS             26242..26514
                     /locus_tag="ACIZD4_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGC5990286.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26525..27571
                     /locus_tag="ACIZD4_001340"
     CDS             26525..27571
                     /locus_tag="ACIZD4_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HGC5990287.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            27822..30431
                     /gene="clpB"
                     /locus_tag="ACIZD4_001341"
     CDS             27822..30431
                     /gene="clpB"
                     /locus_tag="ACIZD4_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HGC5990288.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30582..31268)
                     /locus_tag="ACIZD4_001342"
     CDS             complement(30582..31268)
                     /locus_tag="ACIZD4_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990289.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31246..31740)
                     /locus_tag="ACIZD4_001343"
     CDS             complement(31246..31740)
                     /locus_tag="ACIZD4_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HGC5990290.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(31760..32980)
                     /locus_tag="ACIZD4_001344"
     CDS             complement(31760..32980)
                     /locus_tag="ACIZD4_001344"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5990291.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33127..34962
                     /gene="lepA"
                     /locus_tag="ACIZD4_001345"
     CDS             33127..34962
                     /gene="lepA"
                     /locus_tag="ACIZD4_001345"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGC5990292.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            35158..35748
                     /locus_tag="ACIZD4_001346"
     CDS             35158..35748
                     /locus_tag="ACIZD4_001346"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990293.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGVSQTKRY"
     gene            36143..36638
                     /gene="dfrF"
                     /locus_tag="ACIZD4_001347"
                     /pseudo
     CDS             36143..36638
                     /gene="dfrF"
                     /locus_tag="ACIZD4_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322211.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
     gene            36743..37399
                     /locus_tag="ACIZD4_001348"
     CDS             36743..37399
                     /locus_tag="ACIZD4_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HGC5990294.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            37581..38111
                     /locus_tag="ACIZD4_001349"
     CDS             37581..38111
                     /locus_tag="ACIZD4_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HGC5990295.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            38657..38899
                     /locus_tag="ACIZD4_001350"
     CDS             38657..38899
                     /locus_tag="ACIZD4_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HGC5990296.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            38896..>39261
                     /locus_tag="ACIZD4_001351"
     CDS             38896..>39261
                     /locus_tag="ACIZD4_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HGC5990297.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSY"
BASE COUNT        13320 a         6703 c         8381 g        10857 t
ORIGIN      
        1 aaaaagcttt ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt
       61 gaaaaaatat ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat
      121 ccatcgtttt atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga
      181 cacatttcga gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag
      241 aaatcggaat gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt
      301 ggattttttt gtcataataa atattagatg atggaggaga taatatgatg caaacatggt
      361 tagaaaggct aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga
      421 aatttgatca gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc
      481 gttggttgcc ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat
      541 ttcgtttcct atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat
      601 atcttgatag agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg
      661 atcgaaaaag ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta
      721 aaggaaaagg acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg
      781 tttaagggag aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt
      841 tgaaaattac tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc
      901 agcagttgcc ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc
      961 tgttttgaaa cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg
     1021 gcttcctata ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa
     1081 aaacaaagat aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg
     1141 atatacggaa gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt
     1201 ggatccgcat ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc
     1261 cttatggcaa gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg
     1321 tcatggtaat agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat
     1381 ggatacgatc gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac
     1441 aattctggac aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa
     1501 agaagcaaag gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac
     1561 attgtttgat acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg
     1621 tatcagtatg gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt
     1681 gatcaatgaa tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa
     1741 agaaagtacg gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa
     1801 agacaacggc ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct
     1861 gttaaaagaa catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt
     1921 tcctcgtaaa cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag
     1981 aacagacacg atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg
     2041 agtcgctact tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt
     2101 ggtaggaaat ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct
     2161 ttcaaaggag atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa
     2221 gacaaaaaga agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag
     2281 aaacagattt gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag
     2341 aacatagcat cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat
     2401 ctggaagtgt gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg
     2461 tcacacaaga agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt
     2521 cttatgaggt gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag
     2581 aaaaacaaga atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt
     2641 ttttttatta ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat
     2701 aaaagtcact gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt
     2761 tacttccttc gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat
     2821 cacagtttta gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa
     2881 gcgccataca aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg
     2941 cggtctgctt caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg
     3001 gatcgggatt gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt
     3061 gtttatttcg atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat
     3121 tagtgcgact gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat
     3181 tggttcaaca atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac
     3241 agcacgaatc tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca
     3301 gcagatttta tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac
     3361 aagtacgatt ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa
     3421 aagaaaagcg ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat
     3481 cattatgcgg atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat
     3541 gacaaacgtt ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt
     3601 tgcttcttac gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc
     3661 aaaagtcaat ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac
     3721 ttcacgttca agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg
     3781 agtagatgat gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg
     3841 ctgtgctggc gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa
     3901 tgtctttagt ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg
     3961 tgtagctgga gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa
     4021 cttgccagta gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg
     4081 tacagcagta aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa
     4141 agatttagat cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc
     4201 aaaaagaggt tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat
     4261 agtttctcaa atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg
     4321 tgaataagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa
     4381 tagttcctca tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac
     4441 cgtttaagaa agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa
     4501 aaaatagctt ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa
     4561 caccgtttac cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca
     4621 tataaataca cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt
     4681 atttattatt aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat
     4741 tttcccattt tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga
     4801 ggaaacagat gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa
     4861 atgcaacgtt ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga
     4921 cgcttataat tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag
     4981 catttgttga gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca
     5041 gtaaagatat ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata
     5101 tggtacagct tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg
     5161 cggttacagg taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga
     5221 agtcttttta attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata
     5281 cacaagcaaa taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga
     5341 aggaaggaag aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga
     5401 agaaccagag gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg
     5461 tcgtattcta gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac
     5521 gactgcctat atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat
     5581 cgatccaagc gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt
     5641 aagtttaaag ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc
     5701 gcaagaattt aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga
     5761 ttatgaatat gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg
     5821 agagcttcca gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac
     5881 ctactgtact ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt
     5941 caaagatgtc ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca
     6001 aggagaatta tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa
     6061 ccaagtagat aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata
     6121 tatcaattgt agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga
     6181 aaaacattta ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca
     6241 agaccatgga atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa
     6301 aacaatagtt ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg
     6361 atccacatga aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt
     6421 gaaaaactta ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc
     6481 aatgatcgag gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa
     6541 acaggagcca tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca
     6601 ccggaggact ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg
     6661 attcacccag gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg
     6721 agatattcag aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat
     6781 tatctttttg tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta
     6841 agagacttta tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca
     6901 attgtatttg gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc
     6961 tggattcagg atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat
     7021 ggggttgttt ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga
     7081 ccttggcatg gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct
     7141 ttttattttt atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga
     7201 tagaataaag aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc
     7261 agacgatcat tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta
     7321 ctgtacttaa tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag
     7381 aaatgactgg aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc
     7441 ttgaaaactt agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac
     7501 tgactcccga gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt
     7561 tgtatcgtcc atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac
     7621 ttgaaccact cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag
     7681 aaaaatatat tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc
     7741 atgagattat tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt
     7801 atacgtataa caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag
     7861 gcgtatatga aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa
     7921 tattagctac taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg
     7981 aagcagcaat tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt
     8041 cttcattcgt cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg
     8101 agcgagaact gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg
     8161 gcgaaaacct ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat
     8221 ttgatccggc ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt
     8281 tagcaatcga agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg
     8341 gaccagcttt tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg
     8401 gtacagccag tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata
     8461 aaacctatta cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg
     8521 cacgaaaaga atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc
     8581 gcctgcaaga tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc
     8641 agtaccaaca tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa
     8701 cagcggttaa ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata
     8761 tatcaggatt gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag
     8821 aattcaccgc acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac
     8881 aagcaatcgg attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc
     8941 atcccgaaag ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag
     9001 agcttggtac agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg
     9061 aaagcctatc agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg
     9121 gacgagatat gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg
     9181 aagacttgaa accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg
     9241 catttgttga tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa
     9301 aattcgtcaa gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag
     9361 aacaagtcga tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt
     9421 aacaatgagg agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata
     9481 tcattaaaaa gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt
     9541 acaactggcg ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt
     9601 gaagagtcag acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat
     9661 cttcatctag ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa
     9721 aaaacaggag ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat
     9781 tatcgatgcc aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa
     9841 tatcgttgtg gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt
     9901 aatgaagcac aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg
     9961 aatctaaaag actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt
    10021 gaggaactga cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat
    10081 aaagcagcac aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg
    10141 gggcatgcga ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat
    10201 ggcatgagtg aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat
    10261 aaggcttttc tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg
    10321 gagattcttc attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca
    10381 ctgcaacgca ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc
    10441 gcgaatgctg tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca
    10501 gcaaaagaac tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa
    10561 atggaacgtc tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct
    10621 cacattgata tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa
    10681 acggattttt ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg
    10741 gttgaaattt tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag
    10801 aatggacgct agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt
    10861 tgttggtatc aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct
    10921 aaatgtccaa ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc
    10981 aaatatcacg attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc
    11041 aggaaatgca tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga
    11101 agtgattcgc tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt
    11161 aacaggctct cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt
    11221 ccgtccaaca agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt
    11281 cttttcattt gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc
    11341 aatcatgacc aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt
    11401 tacagctttc caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga
    11461 tgcttattta cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa
    11521 cgatgatatc caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta
    11581 tcatggggat gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt
    11641 aaatgcttta ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc
    11701 agaagaaatg ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga
    11761 catgaccgta gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg
    11821 cgcacgccaa aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac
    11881 gcgtacgatt gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta
    11941 cttatgcgat atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct
    12001 tggagcgaaa atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt
    12061 agattatcat gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca
    12121 agcgtatgaa aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag
    12181 tgtccttata aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg
    12241 caacttatga taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca
    12301 aaaacatgag aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt
    12361 cacgacctct gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg
    12421 ctacttttgg tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat
    12481 aggtaagccg agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc
    12541 cttaacagaa tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc
    12601 aaatcctttg tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt
    12661 tccatcagtg atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc
    12721 aggatcacat gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac
    12781 actgactttt cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc
    12841 tgtagaagcg gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc
    12901 gccacaagtt cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc
    12961 caagtacatc aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta
    13021 tgggacttgc ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat
    13081 tagcaacttt tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga
    13141 ttttagtaat ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat
    13201 ttattgccta ctctcttttg aatggcataa cattagcggt tactcttgca tactacgata
    13261 ttggaacagt aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg
    13321 tcggagtaac aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa
    13381 tcggagtgat cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc
    13441 tgttcatctc cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa
    13501 gcatccgtaa tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca
    13561 tggcattgaa gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg
    13621 gacggaacaa ctaaaaaaga aaaaaattca tcagttgggg ctataccgaa ttatttggta
    13681 tggtcccgct ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt
    13741 acagtaagga gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt
    13801 ggcttttcgc gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg
    13861 tcttcataca aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga
    13921 gcaaccgact catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat
    13981 gtatgcggag tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc
    14041 atatatacgt gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga
    14101 agcagatgat attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt
    14161 cgtgctttca ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat
    14221 cactgtaaaa ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata
    14281 tgatgggttg acgccaaaac agattattga catgaaggga ctagccggag atgcctctga
    14341 caatatcccc ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata
    14401 tggctcagtc gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga
    14461 aaatctgata aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac
    14521 ttcagcgcct gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa
    14581 actcgttccg ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt
    14641 agaagaagaa gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga
    14701 aatgtttact acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga
    14761 ggaaatcgtc ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc
    14821 tgtattcgaa aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt
    14881 atatgatgcg aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat
    14941 cgattttgat gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat
    15001 cgaaggaata gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg
    15061 caaaggggcg aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg
    15121 aaaagtagct gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa
    15181 ccaagaagat cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga
    15241 aataagcggg atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc
    15301 tcgcttaaga gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa
    15361 ttcaccaaag caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa
    15421 aacaaaaact ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc
    15481 aatcgtagag gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga
    15541 gggactgctg aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt
    15601 gacccaaaca ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt
    15661 agatgaaggg agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta
    15721 ttcttctgac tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca
    15781 tttgaaagct gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt
    15841 tggaatcgaa aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa
    15901 ttttggtatc gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg
    15961 aaaagcagca cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata
    16021 tatggaaaga atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg
    16081 ccgtcgatat ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg
    16141 aacagctatc aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat
    16201 cgaattggat aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca
    16261 tgatgaactt gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa
    16321 ggaagttatg gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg
    16381 aaaaacgtgg tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga
    16441 aaagaaaaaa tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta
    16501 gtagtaggaa aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca
    16561 gagacaccca tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga
    16621 gggaagtttt taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa
    16681 ggaaaatatc aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc
    16741 ttttttgagg atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca
    16801 atcgtcgaaa aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct
    16861 ttgccagata gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca
    16921 atcaagccat tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat
    16981 gaagcattat gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa
    17041 gaggtagaac aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga
    17101 ggtaccacga ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca
    17161 ctgcatgtct atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa
    17221 acaaaagtgg cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca
    17281 aagtaggatt tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca
    17341 aagtctttca gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg
    17401 ttgagcctgg aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc
    17461 agcctgatgg gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa
    17521 aacggcaaaa acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa
    17581 tcgcctctct aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag
    17641 gtcattatga ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc
    17701 ttcagcgttt gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta
    17761 gtcaacttcc aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa
    17821 caaaagaaaa acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag
    17881 tatctgtgtc aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat
    17941 taaaaaatca aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca
    18001 ataaagaaaa tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa
    18061 agcagtacca agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc
    18121 ggcaagattt gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc
    18181 cagaaagtga ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata
    18241 caggaatcga agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga
    18301 gaaggtgttc atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag
    18361 ttatttctca gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg
    18421 acacaattac gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac
    18481 agtcgcgttt gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc
    18541 tttatataaa atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa
    18601 taattcacga gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg
    18661 cgaatgtgag aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt
    18721 attagtaatc aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg
    18781 actcatccgt tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa
    18841 ccatgtcgaa aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg
    18901 tgaatatgtg atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag
    18961 tgtttatcgc cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga
    19021 taaagcaaaa gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag
    19081 gcatttcctt ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa
    19141 aagcggctcc gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa
    19201 tcggcggaga agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg
    19261 gcaaaggtcc tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc
    19321 aattttatga tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag
    19381 aagatagtga tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag
    19441 catttttcaa agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat
    19501 tccagaagct tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa
    19561 tcacaaaaaa atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag
    19621 aaaacatcga atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag
    19681 cagattcgac attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa
    19741 gtcttgatga tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg
    19801 aattgacact tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg
    19861 aaaaagaact gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag
    19921 aaacagttgc ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg
    19981 cagcgcttca gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa
    20041 tcaagtcaga aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg
    20101 tttctcaatc aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga
    20161 tcaagaataa tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac
    20221 aaaagaaaat cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag
    20281 caaaacaatc aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac
    20341 gggaaaagct tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga
    20401 aaaaagcaga gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct
    20461 agtggaagac gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa
    20521 gtatgctgaa atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc
    20581 acaccaagaa gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt
    20641 cgtgcaagaa aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga
    20701 gccgaagctg acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt
    20761 gttagcacgg caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa
    20821 agatattcaa tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag
    20881 cttagaagcc ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg
    20941 actgtatcta gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag
    21001 agaattagcg attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga
    21061 gatgaaacag gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc
    21121 acctattttg atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga
    21181 agtattcggt gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc
    21241 gaattttaca atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga
    21301 gccgctaaaa gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat
    21361 gactggtcgc aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta
    21421 gtagtaaaag caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc
    21481 aacaagtaat gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata
    21541 tctgtagttg gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt
    21601 tctgttgatt cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga
    21661 caaagcatat ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg
    21721 cttcagttga aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca
    21781 ttcagcaatg acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat
    21841 gaattgaaaa tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg
    21901 tctatcccac cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca
    21961 ataacatttt ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta
    22021 aggagatatg ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat
    22081 tatctagaag gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg
    22141 gtgactttgt ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac
    22201 ccgttgcatt gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag
    22261 gtccttatga atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg
    22321 tacgccttgc aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga
    22381 ttgcgggtat gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac
    22441 gcttaagcgg acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat
    22501 cttggctgca agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa
    22561 aaatatatga aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg
    22621 agctgatgtt cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga
    22681 caagagagct tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag
    22741 aggcacgtca aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat
    22801 gacaatcagc ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc
    22861 tgaagaagga gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt
    22921 aatgatgaca ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga
    22981 tttgctgatt gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca
    23041 gccacaagaa aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca
    23101 cacgaacatg gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat
    23161 tgaagtggag agttatttag taaagactca tgagattcat tataaaaaac tggccgttta
    23221 tgtacctgtg gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac
    23281 acaaggtgat tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga
    23341 agctggtgca caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa
    23401 agttgaggtt attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc
    23461 tcatccttat gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt
    23521 tgggttagga cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca
    23581 agtaaaagaa gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc
    23641 ctctgtgaag cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat
    23701 cgcccaaaga gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat
    23761 gcaaagcgct gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca
    23821 acgatttatc gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt
    23881 cgtttctgaa acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac
    23941 gaaaatcttt tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca
    24001 agcaaaacga ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa
    24061 ttagaagagt taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga
    24121 acattaccaa gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat
    24181 acagcagatt ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag
    24241 tctacgatcg tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat
    24301 ttgaaaaatt atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca
    24361 gatgacaaat cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct
    24421 tctatccctc acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga
    24481 gcggataaat tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt
    24541 cctttaggtg agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa
    24601 gggaaaaatg tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca
    24661 atcgattttc ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa
    24721 ggtttcttcc atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc
    24781 attcgcgatc atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa
    24841 gaagagttga atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat
    24901 tacaacatga aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca
    24961 atgatcgagc ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca
    25021 aaaatctctt acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac
    25081 ggacgattcg aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa
    25141 attgcagaat tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc
    25201 gtcccaatga tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt
    25261 cccgccctct tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt
    25321 ataacaaaag ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg
    25381 taaaagaaaa gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg
    25441 atgcggaatt agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg
    25501 gagacggcac gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg
    25561 tcggattact tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca
    25621 aaaaagaaga agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc
    25681 aagtcaatga tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag
    25741 tttggatcag tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt
    25801 ttaagttatt gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt
    25861 ggaaaggaaa atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa
    25921 attttgacga ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct
    25981 tagatatttt ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga
    26041 tccccggcat tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg
    26101 tgggcactcg aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat
    26161 caaaaggatt aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa
    26221 cagaaagttg gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt
    26281 ttcattgtga atttttactt attttgtctg atggggtatg ataaacatca ggctagaact
    26341 agcggctggc gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg
    26401 ggaggattga tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata
    26461 ggattcgctg caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca
    26521 ggagatgtcg tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt
    26581 gatttttgcc attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt
    26641 gctgtctacc agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat
    26701 cgctgaaggg cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa
    26761 agatgggttc ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg
    26821 aacgctgatc tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc
    26881 aggggtgaca gcactccata tgattatgta caaactggca gtgatcactt atgcattagc
    26941 tggcttggtc atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat
    27001 catcgctggt atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag
    27061 cttgaatgtt caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt
    27121 gcggaaatgg gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac
    27181 cattatccaa gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt
    27241 attttggtat gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct
    27301 actgaccatt tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc
    27361 tggtattggt tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt
    27421 tgacgcagtt tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta
    27481 tggatttgtg tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt
    27541 aaaaaaagag aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca
    27601 aatcaaagaa aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat
    27661 acatacaatc aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac
    27721 tatgtgtata ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa
    27781 gaaataagtg atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga
    27841 ctacgacgct tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc
    27901 aagatatcga cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa
    27961 atttctatac ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac
    28021 tggatgagta tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga
    28081 atttctttcg attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc
    28141 tttcaacgga agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt
    28201 atttgaataa aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag
    28261 gaggagaaag agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg
    28321 gcgttgattt agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg
    28381 aagaaatccg tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga
    28441 taggagaacc cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac
    28501 gcaaagatgt gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat
    28561 tgatcgctgg agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag
    28621 aagtcaaaaa aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag
    28681 gggcaggaaa aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc
    28741 gcggtgaatt acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa
    28801 aagacaaagc gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag
    28861 atacgatcag tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca
    28921 tccatgacaa cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt
    28981 tcttaccgga caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa
    29041 tgaactctat gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg
    29101 aagaagctgc actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc
    29161 aagaagaatt agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag
    29221 aaaaagaaga agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg
    29281 aattagaaga tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta
    29341 cgatacctca attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga
    29401 ttaagatggt tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa
    29461 cgggtatccc cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg
    29521 aaacacttca taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg
    29581 taattcgttc acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc
    29641 taggaccaac tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg
    29701 actcagaaga tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt
    29761 ctcgtctagt cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg
    29821 aagctgtcag acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc
    29881 ccgatgtctt caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag
    29941 ggcgagtagt agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt
    30001 tactgctgga aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca
    30061 acacgctatt acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt
    30121 tatttacacc attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat
    30181 tggcacaacg tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt
    30241 ggattgctga aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca
    30301 ctaaggaagt agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat
    30361 caaaagtaac gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag
    30421 aaatcgtcta atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt
    30481 cagacctcct tttttcaaat aaacagtgtt ccagaagtag tttcttcgaa aaataagccg
    30541 aaatttcttg aagctgcccg cttctgtcac aacctctttt attaggtatt tttcactttt
    30601 tctaatttat aactttcaaa gtaacgctca tcttttttac tttgagacca tgcaaacaat
    30661 cccattaagg cagcacctat cgtatttgtc agcaagtcgc ccatcgtatc catcaatgct
    30721 gctcgtccga caaacagtgt gccatcagaa gcagcaaaac gttgaagatt catgcctaag
    30781 aactggtcgc ataagaattc ccagaactcc caaaacacgc cgcaaagtcc agcaaacgca
    30841 aagccgaata agaggaacaa ccaaggactg gtttttgata tctcagcatc tttcatcaag
    30901 taaccaatca atccatagcc aagagctgtc aggaccattg gactcaccgc atgtaagatt
    30961 ttgtcccaaa aagagatgat actgatcaaa tgcatccctg tgcctaaaaa gacagagatg
    31021 aacaagaaaa accagtaaaa caaaacgatt gctgctggta ttttaagttt gaaaactttc
    31081 aaaatgactt gtggcatgaa aatcaatgca atccctaata aagattccac gataaatgtg
    31141 attccttgag aagtcgaata tttttgtgtg ataaattcat aaaaattata gcagacaacg
    31201 aatacaccaa aagcaagtaa agctatttgc acctttttga tttctttaat cactgaaagt
    31261 ccctccatct aaaaatcttt ttacttctga aagcaactca atttctgaag aaaccacttt
    31321 tccgttcaat ttgatcaaac ctattgtata taagttcagg tagtgaaatt gattttcagc
    31381 tgtttcttgt agtgcagcga tttttttcgg gtgggttccg ccttgctgtc gagtatcagt
    31441 atataagccg atcactggga tgcctttcgc ataagccaca ccgatttccg atgctacccc
    31501 ggcatcgatc gtcagcccat ctagtaaagc aatcattaaa tcactagcca acactttttc
    31561 tgtgtcagca agagcaatca ttcgactgtc tgcataagca gttttgtcat tgattgcttc
    31621 attttcttga ggaagataga tcgaaagctc agaagagagc tctctgattt ctttaactaa
    31681 ctgttggtta tataacaaat cacttttagc aaacattggt gcggcaaaat aaattttcat
    31741 ctaaacatca tcctttttat caaaaataat cgctaaagta agcttccatg tttggaatga
    31801 tacgctctag tgacttcagt gtttcttcat ctgtttctaa ccgttcgatt cttgccaaat
    31861 aagaagcacg gcgataattc atcatcaagc aagtcaatgt ttggatatcc agtcgaacgg
    31921 attttcctat aggttcattt aagacacgga cttgtccctg ttcatcccat gttaaagcga
    31981 agacaccatt attccaagga gcgacaggat cttcaatgat gaaatgaaaa gcatcagctg
    32041 ttccaacaaa cggaaaccgt tgaaggaatt cttttacatc aacgatccga gccataaaat
    32101 atggttcgat ctgctctttg atctgactat cttcaatcaa aaatgctaaa ggctcatttt
    32161 tataaatatc tccatgtacc cagtagatca tggaaaaatg tgcggaaata aagttccata
    32221 agccatttcg agcttcttga tcaagataga acatttcttt tacgtgaaat atttcttcag
    32281 ctacccagta gaacagaaca cctcttggtt catggttgct atcgtagtag acagcggctg
    32341 tgcgctcatc ttcattttcg aaacgccaat actcttccca atgaaaatca ctgcggaata
    32401 aagcaccatg gttttgttgg gcaaatttgt cataaacgga aaatacgtct ggatgatcaa
    32461 ctggtaatcg ctcaaccata ccacttactg ggatttgttt aggtagctgt gtatctctga
    32521 ttttaaagga aagtttatca gacatgattt cccatccttt acgccgatag taggggatac
    32581 tgtaaggata caaataagag atccattgct tattcttgcg catattatcc aatgcaacga
    32641 taattagatc ttgcatcaat ccatggttag catattctgg ataagttcca actccagtca
    32701 caccacccat tttataacgt gcaccgtgaa tattgacttc acaaggatag atagcgattt
    32761 gagagatcag tttattttcg tggaaccatc cgaacacttt cgatacttcc aaaatcggtt
    32821 ttttggaacg gataaaagct cgtttattct caaacccgct ttcctcgatg tctgcttcag
    32881 tcacttggaa cacataggaa agcaattcat tgaattgatc gatatgttct tgagtgaccg
    32941 gttttaattc aagattttct ctaaaatctt tttgatccat tttttcatct ccatttatta
    33001 gcttgataac agtatagcaa aattctacaa aaaaaacttc tatagctgac taattaaaaa
    33061 ctctttaaat tactgctttt cgttggtata atggaaagtg ctgattatat gaaaagagga
    33121 gacgctatgg atataaagaa aatgaaagaa cgccaagagc agattcgtaa tttttcgatc
    33181 atcgctcata tcgaccatgg gaaatctaca ttggccgatc gtattttaga aatgacgcac
    33241 actgtgacgt ctcgcgaaat gcaagatcag ctgttagact cgatggattt ggaacgtgaa
    33301 cgtggaatca cgattaaatt aaatgctgta gaactcaatt acacagcgaa aaatggagaa
    33361 acatatatct ttcacttgat tgacacccca gggcacgtcg acttcaccta tgaagtctct
    33421 cgaagccttg ctgcctgtga gggtgccgtt ttagtggtcg atgcagcaca aggaatcgaa
    33481 gcacaaacat tggccaatgt ttatttagcg ttagacaatg atttggagat cctgccagtc
    33541 atcaataaaa tcgacctacc cgcagcagat cccgaacgtg tccgtcaaga aatcgaagac
    33601 gtaatcggaa tcgatgctag tgaagctgta ttagccagtg ccaaatcagg gattgggatt
    33661 gaagatattc tcgagcagat cgtggaatat gttcctgcac caagtggaga cttagatgca
    33721 ccgctaaaag ctttgatctt tgactctatt tatgatagtt accgcggtgt tgttctaaat
    33781 gtccggatca cggacggtat ggtcaaaccc ggagacaaaa tcaaactgat gagtaatggc
    33841 aaaacatttg atgttacaga ggtcggggtc ttctcgccaa aagcagttgc tagagacttt
    33901 ttgatggtcg gtgatgtcgg ttatatcaca gcaagtatca aaactgtcca agatacacga
    33961 gtaggggata cagtaacgtt agcagacaat cctgccgctg aagctttacc aggttaccga
    34021 aaaatgaatc cgatggttta ttgtggtctt tatccaattg atacttctcg ttacaacgat
    34081 ttgcgggaag ctttagaaaa actgcaattg aatgatgctg ctttacaatt cgaaccagaa
    34141 acctctcaag cattaggttt tgggttccgc tgtggattcc tcggacttct tcatatggat
    34201 gtcgtccaag aacgcttgga acgggaattc aatctagaat tgatcacgac tgcaccatcc
    34261 gttatttacc atgttaataa aacggatggt acgactgcta cagtagataa cccggcagat
    34321 tttcctgaac ctgtaacgat tcaggatgta gaagaaccat tcgtcaaagc acagatcatg
    34381 gtcccaaatg attttgtcgg tgcagtaatg gaactttctc aacgaaaacg gggagaattc
    34441 attacgatgg attatttaga tgattaccga gtaaatgtcg tctataatat tccgctttct
    34501 gaaattgtct ttgacttttt cgacaaattg aaatcaagca cgaaaggcta tgcctcattg
    34561 gattatgaaa tgtctggtta tcaaaaaagc aagttagtga agatggacat cttgctgaat
    34621 ggagaaaaag tcgatgcatt aagctttatc gttcaccgag actttgccta tgaacgtgga
    34681 aaagcaatcg ttgaaaaact gaaaaaacta atcccacgcc aacaatttga ggtgccaatc
    34741 caagcagcta ttggacaaaa aatcgttgcc cgttcagaca tcaaagcctt gcgtaaaaac
    34801 gtcttggcta aatgttatgg tggagatgtt tctcgtaaac gtaaactctt agagaaacaa
    34861 aaagaaggga agaagcggat gaaacaaatc ggctccgtcg aagttccgca agaagccttc
    34921 atggccgttc tgaaaatgga tgagcaagat agtgtgaaat aacttataat caatcgaaaa
    34981 acctattaaa taaacctttt tgagtagatg caacactgag gattatctgt ataaaagatt
    35041 ttaaactgtc atttggttat cacggcgata ctaaaattaa caaaattgga atatttttct
    35101 tgaagatttt tagctgtcag tatatgatga aagcatctca taggaggtgc ttttttcatg
    35161 gttgataatt caagtggaag ggttcttaaa tctctaagaa aagagaaaaa actatctcaa
    35221 aaaaagttag ctgatttagc aggtatttca caaagtactt tagttaaata tgaaaaaggg
    35281 tcaagaaaaa tccctaaaga cgtagataat actctaagca agattctgaa tatagaaact
    35341 ctaataaaag atgaggaaga taagattgag attctcatcg gtaaactaat tgcatacaga
    35401 gatatgaata agttacttaa caaagagtta gctgataata taggaattag tgaagtatta
    35461 ctcagttatg tgttaaatag aaagagaaat ccgtcaaaag aaatgcaaaa aaaaatcgat
    35521 atttttctat taagtaatga aaaagaaatt ttgaaggaga ttaatcgtga tagtgagata
    35581 tttagtttat caaaagacga taaaattgtt atgggaaaaa gaatacgaga agtccgaaag
    35641 aaccgggaag agacgcttga aaaatttggt aaaaacttta ccatctatac aggcaaaaat
    35701 gttataagta gatgggaaaa aggtgtttcc caaacaaaaa gatattaaga aacagcccat
    35761 gtttacctgc ttgcaaacaa aagaatattg ctactagact aagagatact acataagtgt
    35821 gttggtatct cttttttgtt gccgtgaaac agcagactat ttcatttctg cttgattacc
    35881 ttaaaactta ttagtctatg gtttgtcaag ggcttgttgc gtgagaaatg ctgaatatca
    35941 ccctttacaa aacataggct gataagtaac ttttcaaaag cagaaaagaa atggcaatgc
    36001 ttataacaat atgatataat gcagatgaag acaaaaaagg aatttgtcga gctggttagt
    36061 tcgagataat tttgagtttg ttaagatgtg gtgcacttga tggaatcaca ggtacgacat
    36121 catattatgg aggatgaaat agatgatagg tttgattgtt gcgaggtcaa agaataatgt
    36181 tataggcaag aatggtaata taccatggaa aataaaggga gaacaaaagc aatttagaga
    36241 gttaacaacg ggtaatgtgg ttattatggg gcgaaagtct tatgaagaaa tcggtcatcc
    36301 gttgcctaat agaatgaata ttgttgtttc caccacaaca gagtatcaag gagataattt
    36361 agtttcagtt aaatcattag aagatgcatt attattggct aaaggacgag atgtatacat
    36421 atctggtgga tatggactat ttaaggaagc tttgcaaata gtagataaaa tgtatatcac
    36481 agaagtagat ttaaatattg aagatggaga tacattcttt ccagaatttg atatcaatga
    36541 ttttgaagtt ttgatagggg aaacacttgg tgaggaagtg aaatatacga gaacatttta
    36601 tgtaaggaaa aaatgaattg agtaaatttt ggatttaggg tgttttcata aatatattgc
    36661 tttttatgca tatataaatt gttgtaagac aaattccagt ttgtatgggg cgataaaatc
    36721 agaatttgag agaggattga atatgaataa ggaatggtct gaacttaata aaacaatgca
    36781 ggcacaaata aaaaagaaag atacttataa gaggggtatt gatactttac ttactttacg
    36841 aagtcagtta atacaaacct tagtatcttt caaagaagaa ttatgcagag aagattttaa
    36901 ctcaatcccc ttcataaacg ctgatggtta tcatagtaag acgattgctt attctatttg
    36961 gcatattttc cgcattgaag atatagttgt gcatacagtg ataaatgaag atgaacaagt
    37021 attttttgca ggcaattatc aagagcgtat caattcacct atcattacaa caggaaatga
    37081 actcatgaaa cagcagattg cagacttttc aaaacagctt aatctggaag aattatattt
    37141 atatattttc gaagtatggg aaagcactga gaaaatgctt gaacggttat cttatgatga
    37201 attgaaaaga aaaataccga aagaaagaaa aggatactta gaatcgttga atgtagtaaa
    37261 cgacaatgaa aaagcaattt ggctgattga ttattggtgt aataaagata tttgtggact
    37321 aattcaaatg ccgttttcaa gacattggat tatgcacaca gaagcctgtt tgcgtataaa
    37381 gaacaagata cattcatagg caaaaatttc agtttgtaga actaaggaaa ttggaattta
    37441 aggaggaata aagtatggtt agtgatttta taagagcagc atttccatgg attttaatgg
    37501 gtttatttgt agcaatcagt tgttccctta tgagtaaaaa agagaaataa attcctgttt
    37561 gtatttataa aagagaaaaa atgagaaaag tagttttatt tattgccatg agccttgacg
    37621 gatatattgc ggacggtaat ggtggagtag cttggctaaa tggtcatgga aatgacaatg
    37681 aaaacatcga cacttataca gaatttacca aagatataga tactgtctta atggggtgga
    37741 atacttctca tcaggttgtt actgaacttt ctccgcaaga atgggtatat aataaattta
    37801 caacttatgt attaacacat aaagagtgca attcttccca acaaattcat tttacaagtg
    37861 aaaatcctgt tttattattg gaacggctaa aacaagaagc aggaaaggat atttggattt
    37921 gtggcggagc aaatcttgtt cagcagttgg taagcaaaaa tatgattgat aaatattaca
    37981 tttctgttat tcctactctg ttaggaaatg gggttcgtct tttgggcaac atagacaggg
    38041 aaataaagtt aaggctttgt aaaacacaga cttataacgg aataaccgat ttgatttata
    38101 tgcgtagata actagagaga aacagaaaag ctgttaaacc gacggagcga tccgaccacg
    38161 ttggcgggaa aatccttaag atttttccgc catgcttgca agggggcggt tcgcttcggc
    38221 ggttcggcga gcttgcgagc cgttcaaagc ccccgttatc taacaagggg ggcacaaaaa
    38281 acaagaaaca ctatacacta acaagcggaa aacgctgtat ttataaggca aaaccccatt
    38341 tttacagtag tgatataaat tgtacctata tcactatgaa aattgaatag taaatatgag
    38401 aaagacagtt gatttcaaaa aataagaaat tgattgtcgt tttcttttgc agaaatttaa
    38461 gtgcaggcaa ttatggtagt tgtcgtaatt gctgtcagct cagtgtttat cactgatggt
    38521 gtgaaagatt tacggttgga gatgttcaat aagattattg gtgcttaatt atttttattg
    38581 tagtgctgat atgagaatgt tataattggg gtataaaaca tacaaataaa tttgctgaaa
    38641 aatgaggtat caaaatatgg aaaatgaatt actggaaaac ttaggaagac ttcacacaac
    38701 tgaacttggc gttattagaa ttaaaaagaa cttatctttg aatgtagaaa atgtaattga
    38761 atggtgcaaa gaaaaaatta gcctttctaa tgcggaaatc acaagaaaag gaaaaaactg
    38821 gtatataacg attgataatt gtattataac ggtaaatgcg tacagttata ccgttatcac
    38881 tgctcacaag gtaaaatgat aaatttttct ataaaggaat taaacgcatt tgcagttatt
    38941 gggcaggaag tagaactgac taattatcaa aaaaagaata ttcagattag tacacagttt
    39001 tggagaaagt ttaacagtag tttgaaaaaa gcgtatcttt cacaatcagg aaattgggta
    39061 aaatatgctt ttatggaaag aagaaatgga aaactttatt atttctgttc tattccccaa
    39121 agaaccatta ccccagaggg ctttctgtat aaagaaatac cgtcttataa atatttggtt
    39181 gtggagcata ttggtgctat ggataaaata tatgaaactt atggcaagat ttatgaagaa
    39241 attattccta gtacatcgta t
//
LOCUS       DBBGRF010000023        38979 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000023 DBBGRF010000000
VERSION     DBBGRF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 38979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.023"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(180..737)
                     /gene="frr"
                     /locus_tag="ACIZD4_001352"
     CDS             complement(180..737)
                     /gene="frr"
                     /locus_tag="ACIZD4_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGC5990298.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(740..1462)
                     /gene="pyrH"
                     /locus_tag="ACIZD4_001353"
     CDS             complement(740..1462)
                     /gene="pyrH"
                     /locus_tag="ACIZD4_001353"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGC5990299.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1598..2479)
                     /gene="tsf"
                     /locus_tag="ACIZD4_001354"
     CDS             complement(1598..2479)
                     /gene="tsf"
                     /locus_tag="ACIZD4_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGC5990300.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2578..3360)
                     /gene="rpsB"
                     /locus_tag="ACIZD4_001355"
     CDS             complement(2578..3360)
                     /gene="rpsB"
                     /locus_tag="ACIZD4_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGC5990301.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3719..4198
                     /locus_tag="ACIZD4_001356"
     CDS             3719..4198
                     /locus_tag="ACIZD4_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGC5990302.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4415..5506
                     /gene="phnW"
                     /locus_tag="ACIZD4_001357"
     CDS             4415..5506
                     /gene="phnW"
                     /locus_tag="ACIZD4_001357"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HGC5990303.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5499..5627
                     /locus_tag="ACIZD4_001358"
     CDS             5499..5627
                     /locus_tag="ACIZD4_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HGC5990304.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5631..6176
                     /locus_tag="ACIZD4_001359"
     CDS             5631..6176
                     /locus_tag="ACIZD4_001359"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HGC5990305.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6630..8321)
                     /gene="argS"
                     /locus_tag="ACIZD4_001360"
     CDS             complement(6630..8321)
                     /gene="argS"
                     /locus_tag="ACIZD4_001360"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGC5990306.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8741..9688)
                     /gene="arcC"
                     /locus_tag="ACIZD4_001361"
     CDS             complement(8741..9688)
                     /gene="arcC"
                     /locus_tag="ACIZD4_001361"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGC5990307.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9803..10822)
                     /gene="argF"
                     /locus_tag="ACIZD4_001362"
     CDS             complement(9803..10822)
                     /gene="argF"
                     /locus_tag="ACIZD4_001362"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGC5990308.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10913..12142)
                     /gene="arcA"
                     /locus_tag="ACIZD4_001363"
     CDS             complement(10913..12142)
                     /gene="arcA"
                     /locus_tag="ACIZD4_001363"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGC5990309.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            12603..13304
                     /locus_tag="ACIZD4_001364"
     CDS             12603..13304
                     /locus_tag="ACIZD4_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC5990310.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(13913..14929)
                     /gene="tsaD"
                     /locus_tag="ACIZD4_001365"
     CDS             complement(13913..14929)
                     /gene="tsaD"
                     /locus_tag="ACIZD4_001365"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGC5990311.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(14926..15390)
                     /gene="rimI"
                     /locus_tag="ACIZD4_001366"
     CDS             complement(14926..15390)
                     /gene="rimI"
                     /locus_tag="ACIZD4_001366"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGC5990312.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(15397..15939)
                     /gene="rimI"
                     /locus_tag="ACIZD4_001367"
     CDS             complement(15397..15939)
                     /gene="rimI"
                     /locus_tag="ACIZD4_001367"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGC5990313.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(15923..16645)
                     /gene="tsaB"
                     /locus_tag="ACIZD4_001368"
     CDS             complement(15923..16645)
                     /gene="tsaB"
                     /locus_tag="ACIZD4_001368"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGC5990314.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(16836..17816)
                     /locus_tag="ACIZD4_001369"
     CDS             complement(16836..17816)
                     /locus_tag="ACIZD4_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5990315.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(17840..19324)
                     /gene="galT"
                     /locus_tag="ACIZD4_001370"
     CDS             complement(17840..19324)
                     /gene="galT"
                     /locus_tag="ACIZD4_001370"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGC5990316.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(19336..20325)
                     /gene="galE"
                     /locus_tag="ACIZD4_001371"
     CDS             complement(19336..20325)
                     /gene="galE"
                     /locus_tag="ACIZD4_001371"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGC5990317.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            20573..20740
                     /locus_tag="ACIZD4_001372"
     CDS             20573..20740
                     /locus_tag="ACIZD4_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGC5990318.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(20802..22613)
                     /locus_tag="ACIZD4_001373"
     CDS             complement(20802..22613)
                     /locus_tag="ACIZD4_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HGC5990319.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTNENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(22610..22975)
                     /locus_tag="ACIZD4_001374"
     CDS             complement(22610..22975)
                     /locus_tag="ACIZD4_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HGC5990320.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(23138..23533)
                     /locus_tag="ACIZD4_001375"
     CDS             complement(23138..23533)
                     /locus_tag="ACIZD4_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGC5990321.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(23551..24513)
                     /locus_tag="ACIZD4_001376"
     CDS             complement(23551..24513)
                     /locus_tag="ACIZD4_001376"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGC5990322.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(24513..24725)
                     /locus_tag="ACIZD4_001377"
     CDS             complement(24513..24725)
                     /locus_tag="ACIZD4_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGC5990323.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(24746..25444)
                     /locus_tag="ACIZD4_001378"
     CDS             complement(24746..25444)
                     /locus_tag="ACIZD4_001378"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGC5990324.1"
                     /translation="MNYQQQIKLRVWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(25464..26006)
                     /locus_tag="ACIZD4_001379"
     CDS             complement(25464..26006)
                     /locus_tag="ACIZD4_001379"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGC5990325.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(26138..27142)
                     /locus_tag="ACIZD4_001380"
     CDS             complement(26138..27142)
                     /locus_tag="ACIZD4_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGC5990326.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(27139..28128)
                     /locus_tag="ACIZD4_001381"
     CDS             complement(27139..28128)
                     /locus_tag="ACIZD4_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGC5990327.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(28125..28931)
                     /locus_tag="ACIZD4_001382"
     CDS             complement(28125..28931)
                     /locus_tag="ACIZD4_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990328.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            29097..30053
                     /locus_tag="ACIZD4_001383"
     CDS             29097..30053
                     /locus_tag="ACIZD4_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5990329.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(30130..30648)
                     /locus_tag="ACIZD4_001384"
     CDS             complement(30130..30648)
                     /locus_tag="ACIZD4_001384"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGC5990330.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(30736..30885)
                     /gene="rpmG"
                     /locus_tag="ACIZD4_001385"
     CDS             complement(30736..30885)
                     /gene="rpmG"
                     /locus_tag="ACIZD4_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGC5990331.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            31113..31559
                     /locus_tag="ACIZD4_001386"
     CDS             31113..31559
                     /locus_tag="ACIZD4_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HGC5990332.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(31754..33649)
                     /gene="asnB"
                     /locus_tag="ACIZD4_001387"
     CDS             complement(31754..33649)
                     /gene="asnB"
                     /locus_tag="ACIZD4_001387"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HGC5990333.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(33974..34948)
                     /gene="bsh"
                     /locus_tag="ACIZD4_001388"
     CDS             complement(33974..34948)
                     /gene="bsh"
                     /locus_tag="ACIZD4_001388"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HGC5990334.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(35282..35369)
                     /locus_tag="ACIZD4_001389"
     tRNA            complement(35282..35369)
                     /locus_tag="ACIZD4_001389"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(35335..35337),aa:Ser,seq:cga)
     gene            complement(35514..36080)
                     /locus_tag="ACIZD4_001390"
     CDS             complement(35514..36080)
                     /locus_tag="ACIZD4_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5990335.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            36336..37667
                     /locus_tag="ACIZD4_001391"
     CDS             36336..37667
                     /locus_tag="ACIZD4_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HGC5990336.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            37633..37983
                     /locus_tag="ACIZD4_001392"
     CDS             37633..37983
                     /locus_tag="ACIZD4_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990337.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(38075..38494)
                     /locus_tag="ACIZD4_001393"
                     /pseudo
     CDS             complement(38075..38494)
                     /locus_tag="ACIZD4_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(38495..38839)
                     /locus_tag="ACIZD4_001394"
     CDS             complement(38495..38839)
                     /locus_tag="ACIZD4_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGC5990338.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
BASE COUNT        11315 a         8087 c         6759 g        12818 t
ORIGIN      
        1 acttaaaaga ttcccactat cttaagtatt atagcaatat ctaactgttt ttcctatgaa
       61 atcattgttt ttttatttaa aaactgaata attttttctt tttttaattt ttaaataaaa
      121 gaaatataaa taaaaacaga ggaagcggaa tgatccgccc ctctgttttt atgattttat
      181 taaacttcca ataattcttt ttctttatca gcagcgatct tatctacttc tttgatgctg
      241 ttatctgtca atgtttgtac gtctttttct aatccgcgca aatcatcttc ggtaatatca
      301 ccattttttt gttgtttttt atattcatcg atcgcatcac gacggatgtt acgaatcgcg
      361 atttttgcat tttctgcttc ttttttcaca tctttagcta attcttttct gcgttcttct
      421 gtcagttgcg ggataactaa gcgaatgaca tttccatcat tggttggact gattccgata
      481 tcacttgcca taatagcttt ttcaacatct tgaagaatgc tcttgtcaaa aggtgtgatc
      541 attaaaacac gtgcttctgg aatttggatt gatgccattt ggttcaatgg tgttggcgca
      601 ccgtagtagt tcacagtaat acggtccaaa aggctagcgt tcgcacggcc tgcgcggatt
      661 tgcccaagtt cacgttgaag attttgtgct gcttttttca ttttttcttt tgcttctgtc
      721 ataattgcat ctgccatttt tatttccccc ttacagttgt tccgatattt tcgcctaaga
      781 ttgcacggcg aatatttccg tgttcattta aattgaagac aagcagtgga atatcattat
      841 ccatgcttag tgaacttgca gttgaatcca tgacttgtaa tcctttggca ataacttcca
      901 gatgagtcag ttcttcaaat tttactgcat ttgcatctac tttcggatca gcagaataaa
      961 caccgtctac attgttttta gccatcagga taacatctgc gccgatttct gccgcgcgta
     1021 atgctgctgt tgtgtctgtc gagaagtacg ggttgccggt accgcctgca aagataacga
     1081 tccgtccttt ttctaaatga cgttctgctt tacggcgaat atatggctct gcgatttgac
     1141 gcatttcaat cgaagtttgc acgcgtgtcg gtacacccac gttttccaac gtatcctgta
     1201 aagctaaggc attcataact gtagctaaca tacccatgta atcagcttga gcacgttcca
     1261 tgcccatttg tgctccgatt tgtccgcgcc agatatttcc gccgcccaca acgattgcca
     1321 tttcaacgcc cagctcgtga acttctttga tttcttggat gatttctttg attactggtg
     1381 gtttgattcc aaatcctgcg tccccagcta aagcttctcc actcaatttt aagactacac
     1441 gctgatattt cggtgtgacc atgttcattc ctccaatatt ttctattgcc attttaccat
     1501 acttagatga tttcgacact ctaagactgg tttttcttgt tttgcttaaa aaaagggagc
     1561 gcacaaaccg tgcgttcccg tctgttattc aacagaatta ttttttcact tggctcataa
     1621 cttcttctac aaagttatct tcgcgttttt cgataccttc gccaacttcg aaacgtacga
     1681 atgttttaac agttgcgcct tttgatgcaa cgtatttttc aacagtcata tcaggatctt
     1741 taacgaatgg ttggtccacc aaagcgattt ctgctttgaa tttcttcaag cgtccttcta
     1801 ccattttttc aacgatattc gctggtttgc cttcgttcaa tgcttgttct gtaagaacag
     1861 ttttttcatg ttctaattca gcttctggaa tttgtgattc gtttacataa cgaggattga
     1921 tagctgctac gtgcatagct acgtctcttg caactgtttc gtcagttgtt ccatctagaa
     1981 cagtcaatac ggcaatacgt ccgcccatat gcaagtatcc accaaatgca gcattgtcgt
     2041 ctttttctac aacttcaaag cgacggaagc tgattttttc tccgataact tgagttgctt
     2101 cgatcaagtc agattcaatt gtacctttat ctgttttgat tttcattgca gcttccatgt
     2161 ctgctggttt gttttcagca acaagttctg caatttcttt tactaaatct tggaacattt
     2221 cgtttttaga aacaaagtct gtttctgagt ttacttcaac gattgctgca gtgttacctt
     2281 tcacagcaac tgaagccaat ccttcagctg caatgcggtc atttttcttc gcagcctttg
     2341 ccattccttt ttcacgtaaa agatcaactg ctttttccat gtcgccttct acttcaacta
     2401 atgctttttt cgcatccatc attcctacgc cagtcatttc gcgtagttct tttaccattt
     2461 tagctgtaac gtctgccatg tttaactcct cctgtgtgtt tttcttttta aaaaaagctg
     2521 cttcaaagga gagtgaggct tgtcgcccag cctttgaaac agctccatca ttcaaaatta
     2581 ttctgctgaa gaattgtcgc cttcaacaac atctacgatt tcttcgattg atgttgctgt
     2641 gttttcttct gtgaaatctt cttcaactac ttgatcttca ccttggtttc cttcgatgaa
     2701 agcatcagcc atttttgaag taatcaattt aacggcacga attgcatcgt cgtttgaagg
     2761 gattactacg tcgatttcat ctggatcgca gtttgtatca accatagcta cgattgggat
     2821 atttaatttg tgtgcttctt gaacagcaat acgttcttta cgtgggtcaa cgatgtacat
     2881 tacatctggg attcttggca tatcagcgat accgcctaag aatttttcaa gacgttcacg
     2941 ttctttgttc aaaccagcaa cttctttttt aggtagaact tcaaaagttc catcttcttc
     3001 cattgcattg atttgtttca aacggctgat acgtttttgg atagtatccc agtttgtcaa
     3061 tgttccgcct aaccaacgat ggttaacgaa gtattgtcct gcacgagttg cttcttcttt
     3121 gattgcttct tgtgcttgtt tttttgtacc tacgaataat gctacgccgc cttcttcagc
     3181 aacgctcttc atgtaatcat aagctgcatc tactaattta actgtttttt gcaagtcaat
     3241 gatgtagatt ccgtttcttt ctgtgaagat atatttcttc atttttggat tccagcgacg
     3301 agtttggtga ccaaagtgta cgccggcttc tagtaattgt ttcatagaaa ttactgccat
     3361 gtttgtttcc tccgatttgg ttttattttt cctcttctta tcttctacct tgccggcaaa
     3421 ctttttcaag cacctaccga caatccaata agaatgtgga tttgctgatg cataaagcac
     3481 cctcagctat tatacagaca aaagatccgt atcgcaagag caaatatact tttctgctca
     3541 acattcaata gtttacctga aagataaaaa gaattcaaga aaaacagtag atttctcttt
     3601 gtttctttat tatccttttt ccataaaata attttaggta taaaagacga atattattgg
     3661 gcaatccttc ttttttttgt tatgatacat gtgaaatctt tcgtaaagga gaaagaaaat
     3721 gcgcaaagct caaagacatt tgctgattaa acaagtcatt gaagaattcc cgatccgtac
     3781 gcaagaagaa ctattaaaca aacttgggca ttatggcgtt accgccacgc aggcaacgat
     3841 ttctcgagat atccgtgatc taaaaatcgt gaaggcacct gatgaaaatg gcgtttcccg
     3901 cttcgtattg tttcgcgaaa aaggaactcc tgagactagg actgaggaag aggatcggct
     3961 ggttcaaatg attgaagaca ttgtattgaa agtcgaacga gtccactttt tgacgatcgt
     4021 caataccttg ccagacaatg ctcatttatt tgcatctgtt ttagatgaga tcaaacctcc
     4081 ctctattgtc agtacaattg ctggattcga tacgatcatg gtcatctcgg aaaatgagga
     4141 ggacgcaaaa cgagtagaag aatttcttca ccatccaact gaagtatcac ttttttaatc
     4201 agagcacgta ttcctaatat ggaatgcgtg tttttttatt ttcaatattt tccttattga
     4261 ataaaccttt acactcttta caaaaataca tcatttttta ttcaaatttt tcaacacctt
     4321 gattgaatca caataatcat catttatatt ggatgttaac aagagcagct tcttgctctt
     4381 tgtgtatttc aaaaaagaaa tgaaaggaaa tcatatgtat aaattattaa cttctggacc
     4441 attgacgact tctgaaacag tgaaaaatgc tatgctgatc gatcattgta cttgggatca
     4501 agaatacaaa gaaattacac aatggataag aaaaaaatta ttggatcttg ctcaagtatc
     4561 ggaaggaata tacacaacgg tcttaatgca aggtagcagc tccttcgggg tagaatcggt
     4621 attaagttct gtgatcaggc cagaagatac tgtactgatt tgttcaaacg gcgcatatag
     4681 acaacgaatg atcaacatgt gcgaatgtct gaaactgaac tataccgttt atgaggtatc
     4741 ggaacatcaa atcctccaag ctcatgtgat tacacagctg attgaagaga atccgtctat
     4801 ctccgcacta gcaatggtcc atagcgagac tacttccggt attttgaata atttggaaga
     4861 gattgctgct gtcacacaag aaagagatct tttgtttata gtggacgcga tgtcaagctt
     4921 tggtgggata ccgatttgtg tagccgaact agggattgat tttttgattt ccagctcaaa
     4981 caaatgtatt caaggtgttc caggcttttc ttttgtactt gctaataaag cggaactgga
     5041 aaaacgaaaa aatgttagcc gaagtttgtc acttgatcta tatgaccagt accgcgtgat
     5101 ggaaaacgag aatggcaaat ggcgtttcac ttcccctacc catacggttt tggcttttca
     5161 acaagcgctg aaggaactag aggcagaagg aggaatcgaa actcgatatt cacgttatct
     5221 cgccaataat catgtgctac gacaaaaaat gacagagatg gggttccagc ctttcattca
     5281 agaatatcag gggccattca tcacctcttt tctttaccct aaggactggc gatttgattt
     5341 taatcatttt tatcagtatt taaagcaaaa tggatttgtg atctatcccg ggaaaatcag
     5401 cgatcatgaa tgttttcgta tcggaaatat tggcgagatc tatccggaag atattttgga
     5461 actgacagca attatcaaag actataagga gaacgttaat gattaaaact gtaatttttg
     5521 attgggcagg aacaactgtg gactttggct gtatggctcc tgtccacgct tttagaaatg
     5581 cttttctaga aaaaggaacc caactgactg acaaagaaat ccgctaaccg atgggaaaat
     5641 taaaatggga tcatatccaa cagcttcttt ccctcccttc tgtcaaaaaa caatggatag
     5701 ctatttatgg acaactacct caggaaaaag aggtggagga attgtatcaa caatttgaac
     5761 attatctgtt taaagatttg gtcaagcatt ctaccttgaa acccgacaca ttggaaacga
     5821 tcgaacggtt gagaaacgct gggatcaata ttggttccac gaatggattt aatgctccta
     5881 tgatgacaat cgtagcagaa accgcaaaaa aagaaaggta ttcaccagac ttcatggcaa
     5941 cttttgaaga cgtcgaaggg tatggtcgac cgtttcctta tatgatccat aaaaacatgc
     6001 agtacttcaa aaacaagtcg gttgatgaag taatcaaagt cggagatacg gtctcagata
     6061 tccaggaagg gaaaaatgcc ggagtgttga cagtaggtgt aattgaaggt agttcgctaa
     6121 tggggatttc ttatgatgag taccaaaaat tagagatggg gaaaaagatc gtttaaaaca
     6181 gtctgttgct cttagattcc aacaagccgg cgctgatatt tgtgtaaaca atttaaaaga
     6241 gttaacagaa tacattttgt acgctgacaa gaatccagaa tgacttttat acaaaataag
     6301 aggttgtgaa aaagctgtcc tgtatcaagt aataaaaaca gccaagcaaa aatagctcct
     6361 catatttttc gtttggttag gcttattacc gcagatgcaa gcttttgaac accgtttatt
     6421 cgaaaaaaaa aagggagctg tgacacgact tttgtcacag tccccttatt tgcaaacaaa
     6481 cagtgtttaa gagacaacct ctccactaaa cggtgttcat tcagctgact ctcggtattt
     6541 gctcaaaaaa cgataaaatt tgaaaagcta ttttctcttt tgtttctcta atactcggat
     6601 cagaacgctg atttcacatt ctctttttct tacatcttat ctggtgcatg aagtcctagc
     6661 aaacgaaggt cttctttcaa taatacagtc actgcataaa ctagagctaa gcgtgcttct
     6721 ttttgttcat catcagctaa aatcttcgta tgagcatagt atttgttgaa tgcttgtgct
     6781 aatttgattg catgtttcgc aatcactgac ggttcgtatt tttccccagc agacaagacc
     6841 gtttcagggt atttttgaac taatttaacc acttcccagc tggtatcgtc attcaatgca
     6901 tagtctgctg tttctgaagg gacaaatcct gctttttcca acaggctgac tgcacgagca
     6961 tgtgtatatt gcacataagg tccagtttct ccttcaaatc gaacaacttc ttccaggtta
     7021 aagtcaaatg tattcagtcg atcgtttttc aaatcgtgga aaatgactgc cccaacccca
     7081 acttgtttag ctacagcatc tttgttttcc aaatcagggt ttttctcgct gatttgttct
     7141 ttagcagatt ggattgcttc atttaatact tcttctaata agacgatctt tcctttacga
     7201 gttgataatt ttttaccacc ttgcgtgatc aaaccaaatg gaatatggtg catgtcgtca
     7261 gaccagtcaa agcccatttc cttcaagaca gctttcaact gtttaaaatg atagctttgt
     7321 tcattcccta ctacatatag agattgtttg aagtcgtaag tacgtttacg gtacaatgca
     7381 gcagctaagt cacgtgtaat gtatagtgtc gcaccgtctg acttcttaat caacgctgga
     7441 ttcaggtcat aagcagatag gtcaacgatc tctgcacctt tatcctcgtt cagcaaatgt
     7501 ttttcttcta aaagtttgac gatttcatcc atcttgtcat tgtagaaagc ttcaccgttc
     7561 aacgaatcga aacgtacttc cagcagatca tagattttat tgaattcttt catcgattca
     7621 tcacggaacc attgccataa ttgaatagcc tctttatcgc cttcttccag acgtttgaac
     7681 caagcacgag cttcttcatt taattctggt tctgtttcag ctacttcatg gaattggacg
     7741 tataaacgaa gcaattcatt gattggttct gctttaacag cttcttctgt accccatttt
     7801 ttgtaagcga cgatcagttt tccaaactgt gttccccagt cacctaaatg gttgatgcgg
     7861 attggctgat aaccgatttt ttccataatg aaaccgatcg aattaccgat aactgtcgaa
     7921 cgcaaatgtc ccattgagat tggtttggca atattaggag aagacatgtc gattggtact
     7981 gttccttgat tcccgatgtt gctatcccca taatgttctt tttctttcac tactgtttgc
     8041 aaaacttttt tgctgataag ttctttattc atgaaaaagt tcaagtaagg tccgacaact
     8101 tcgatttttt caaagttggc agaatcgatt ttttctgcta aatctgcagc gatttgctgt
     8161 ggcgcttttc ggtaaacttt tgctaatgaa aaggctggaa atgcaacatc tccgtgttca
     8221 gctgattttg gattttctag taattgctcg acttgttcca gtgttaaatc atctttgaca
     8281 gcgtcataga cagcttttgc gacaagatct ttattattca tctttattcc tcctaaagtg
     8341 ttcccttgat tgttaaacaa aaaaaatctc tagcgacggc atacttagta tgccatcact
     8401 agagacgaga tttcccgcgg taccactcca attgtcctaa aaaaggacca gctccatctg
     8461 atatcggtag acgaccgtct gtttaaaaca gaattctcca agtgcgcttc gttgtatctt
     8521 cttcattcgg cttccaccac ttccgaattc gctagccaag aatgatacaa gtactctctt
     8581 gttcaacaaa tcttagtctt attaaacttt cttgaattat atcagaaaaa aaaacgaaag
     8641 gctagtcgtt tcataaaaaa aaaatccaga tggcctaaag gagaagaaat accacctgga
     8701 tagctataaa tcatttcgta aatacgaaag acttaacaaa ttaatcagct acgataatcg
     8761 ttccttcttc agaagctaaa agattctcga tattttctaa agaagtgatg attgccttag
     8821 cgtttggttt tgcttcaaca aatgcaatag ctgcttctac tttcggaagc atgcttcctg
     8881 gagcgaattg cttttcatca atgtattgtt tcatttctga aacagtaaca gtttctaatt
     8941 tcttttgatc tggtttttgg taattgacat acacattgtc tactcctgtc aatacgatca
     9001 gcaaatccgc atcgatgatt tcggctaatt tttctgaagc aaaatcttta tcgattacgg
     9061 cttctcgtcc ttctaatcca gtagctgttt ctacaacagg aatcccaccg ccaccaacag
     9121 agactgtgat aactccttga tcgaccagcg tttcgatgac acgtgcttct ttaatcgaga
     9181 tgggtttagg ggaagcgact acttttctcc atccacgtcc agcatcttct ttgaatgtca
     9241 cagtggagtc agcattcatt tgttctttgg cttcttcttc cgtgtagaat ggaccgactg
     9301 gtttacttgg atttttgaat gaaggatcat tttcatccac aataacttga gtgactaaag
     9361 aaaccacatc tttatcgatc cctttttcct tcagtacttc gcccatggcg ttttgtaacc
     9421 agtaaccgat agatccttct gtcattgcaa cacatgtatc taaaggcatt gccggtgttt
     9481 tctcagaatc agcagcttgc tgctgaatca ataggttacc gacttgcgga ccatttccgt
     9541 gggagatgat caattcatct ccttgttcga taaatttcac taaatacttt gctgtttcca
     9601 ttaacgcttc ttgttgggct tttgcacttg catccgtaga caagatggca ttgcccccta
     9661 aagcgacaac tacttttcgt ttggccattt cattcgtcct ttcttcagtt ctaccgaatt
     9721 ttctagataa caaaacgagc cagcgttttg tgattttccc tcaatgctga ctcgtttttt
     9781 cgtgagatga atgtggttat gcttaaacgc gagggataaa caagttacct aatgttgctg
     9841 ccatgatcgc tttgattgag tgcatacgat tttctgcttg gtcaaattga cgagcatatt
     9901 tgctgcggaa gacttcatct gttacttcca tttcagtgat gccaaagcgt tctttcattt
     9961 gttcaccgta aacagtgttt gtatcatgga aagctggcaa gcagtgcaag aagatcaaac
    10021 gatctgtgtt gtgtgttttt tctaccattt ccatattgat ttggtaaggt ttcaacaatt
    10081 tgatacgttc ttcgaattta tcttcttcac ccattgatac ccatacatca gaataaagga
    10141 cgtctgctcc gtctacacct ttatcaacat cgtcggtaat catcaattgt gcaccggatt
    10201 tttcagcaaa gccttctgcc attttgacga tttcttcttc aggttgtaat tcttttggtg
    10261 caacgatacg catattcgct cctaaaattg cacctgtgac taataaagag ttagccatat
    10321 tgtttcgacc atctccgcag taagcaacag tgataccttc tactgttcca aagttttctt
    10381 ggatagttaa aaagtcagcg atcatttgtg ttggatgcca ttcatcagtc aagccattcc
    10441 aaactggaac accagagaat tctgctagtt cctctaccat tttttgactg aatccacgga
    10501 attcgattcc gtcaaacata cgtcctagta ctttagctgt atcttctgtg gattcttttt
    10561 tacctaattg gatatcattt gcacctagat attcaggatg tgcacctaga tcgatcgctg
    10621 cagtagtaaa tgcagaacga gtacgtgtag atgttttttc aaataaaagc gcaatatttt
    10681 ttccttctag atagtgatgt gggataccac gttttttcaa gtctttcaag tgttctgaaa
    10741 aatcgatcaa atattgtaat tcttcttttg taaagtcttt ttctgctaat aagcttcttc
    10801 cttggaatac tgattctttc atattaaaca ttctccttta gattgttttt atttaagatt
    10861 aaagaggaaa tcccgacggc agctgacagt aagactgccg tcaggaaaca aattacttca
    10921 agtcttcacg gacaagtggt tggctcatgc agcgtggacc accacgacct cgtgacaatt
    10981 cacttgaatt gatttctaac actttgatgc catagctacg aagcaattcg ttcgatacat
    11041 aatttcggtt ataagtgact acaacacctg gagcgattgc caatgtgttt gatccatcat
    11101 tccattgttc tcgaggtgca acgatctcat ctccattacc agttgggatc agtacaagat
    11161 catctaatcc aagagcagct ttcatcgttt cgtgtaagtt atctgaatga gtaatcttga
    11221 tatcatcacc atctggttcg attgtaaaga catccatctt accgtcttta ctttgaattg
    11281 ctggatggat agtgaattta tcgtgatcta ccattgtaaa tacggtatcc aaatgcatca
    11341 ttgcacggtt gttcggaatt ttgattgcca acactttttc aaatcctgaa ttttttgcga
    11401 ataggtggcg tgctaatttt tctaaagctt tcgcattagt tcgttgagaa atcccaacag
    11461 ctactacttt atcgcttaag atcaattcgt ctccgccttc gatatgatct ggattttcac
    11521 gatccaacca tacttcgatt cctttatttg caaatcttgg atgatgtttc aaaatatatt
    11581 ctgtaaacat cgattcacga cgacgtgctt caaaagtcat cttattgact gtcatcccat
    11641 ttcccattga tgcggaaggg tcgcgtgtaa agtacaagtt tggcattggg tccatgtaaa
    11701 atggatagtc atcgtctgct gacagatcat atagactgct agaacgtact tcgatatctt
    11761 ttgtacgaac cccagccatg attttatcta ccatttcttg cgtttccatt gatagaagga
    11821 actcatgaag accctctctt acagcattcg atgcaatatg agattcatcc aacattttat
    11881 tcaagaattg ttctttgaca ttgcctgcgt caatcgcttc tgccgctaat ttttccaagt
    11941 aaagagtctc gacgccttca ttttgcaatg tcttcgcaaa gttgtcatgt tcttcttgag
    12001 caatcggaag atatggaata tcatcgaaca acagacgatc cataatatct ggtgtcaaat
    12061 tttccacttc ttgtccaggc cgtttcagta aaactgtctt taatttccct atttcagaga
    12121 aaacgtgaat aggtttatcc atgttgtgtt gcctccttct ttttgattac atgtatagga
    12181 tatcctcctt ttgtaatcac tttcataatt ttgtctcatt caaaatgaga cattcctcac
    12241 attaatattc gataattaaa taattaaacg tttttctatt tttaagcgta atttattcat
    12301 tttttattct gtatacactt tcaaaaaaat atttattcat tgaaaaaatt tttttgaata
    12361 aattaaaaaa ataaattata ttatcgttgt tagcgtttac tatatgtatt attgttgttt
    12421 tttatacaca aatcattcgc ttcaaaacaa attattcaat accattgtat attttttaca
    12481 taataacaaa ttatatttgt aaagtattaa aacttgtttc taatgttggt atgttaaaac
    12541 tttacaaatt ctttaaaaaa agtgacaata aatatagtga acaataagga gaggactttt
    12601 taatgcgtgt taataaaatc gattttcact tttcaaaact cagatatcaa cctgattttg
    12661 aacatttctc ggatgaagag ttccaacaga tcaaggaaca tactgttctt cgttcttata
    12721 aaaaaggaca gatccttttc gacgatggtg atcccagaca acggttgtat atcttgacca
    12781 aaggactcgt tcgtttagaa cgttatgatg aaagtgcaac ttattactac tatgactatg
    12841 tgaatacaaa taaccttttt cctatgtcag gaatgtttgg agaagagacc tacacttata
    12901 cagctcaagc gatgactgat attgaaacat tctaccttcc tgtttcctac tatgaaaaat
    12961 tagcacgaaa aaatcccgaa cagttgatct atatgataca aaaaatttct aaagtagttg
    13021 aaatacatga attgcgtatc caaatcggat tgacctctag cgcctttgac cgggtaaaac
    13081 aaaatttatt cattttgaaa gaagaattgg gcgtaccaac aaaagatggt catatcacca
    13141 ttccttatcc gatcacctta aaagaattag cagtgaatag cggcacgaca cgtgaaactg
    13201 ctggacaagt aatcaaacaa ctacgtgatt ccgggctgtt agattatgac aaaaagcgtt
    13261 ttactttctg taagacagct actactccag ctatgagaga ataacgcgaa caaaaataag
    13321 cagtgaccct gataaatatc agggtcactg cttattttcc tccctaaaac ttctgaaaga
    13381 tccggcagtt ttagatcact ggacaagact caaagatttt ctatgtgtgt ttcagttatg
    13441 taatattcac tgtttgcaaa aaatactgtt agattaacta gatgaagcgt cttgtcctca
    13501 tccgatctag attattcgat attcctcgac aataaacgat tactcagtga gggcaatcag
    13561 aggaacggat aatgataaat aagctgtaaa aaatagcaaa ataacaataa tgattaaaag
    13621 tatgtaaaaa atagggcttt gacaaaaacg tgtcacagcc ctatttcgat taaacggtgt
    13681 gtacctgtca actcttcggt cacaagtcat aatgttcata aacatgagga gctgtttttt
    13741 gaaattgttc cttgtgaatc agagttaaac gacaggctta cgaactcttg attaaacggc
    13801 gttcaaaagc ttgcatacgc ggtaataaga acagccaggt caaaaacatg agaagccgtt
    13861 tttcctgggc tgttcttatt acttgatgca gggcagcttt ttcacaacct ctttattcag
    13921 ataaaaccaa gcttggatca gcattcaact gatagctagc aaaatttctt ttttgcattt
    13981 ccacatgtgc tgctgctcca atcattgcag cattatctcc acaaagtcga agagggggaa
    14041 tcactagttc tacctcaggg agtttagttg ccaaagcatc ctgcaatcct tcacgcaacc
    14101 cttgattggc cgctacacct ccagctataa tcagttgctt gactggataa ttttgacaag
    14161 ctcgaagtgt tttagtaatc aatacatcga tcacacttgc ttgaaagcta gctgctaaat
    14221 catttttgtc tagatcttct ccacgctgtt gtgcattatg caccaaattg ataaatgcac
    14281 tttttaatcc gctaaaactg aaatcataat tatcttcatg gatcatcgct cgcggaaaat
    14341 ggtaattatc ttttccctga tgagctagct gatcgatttc ttttccgctt gggtaagaaa
    14401 gacctaatac tcttccaact ttgtcataag cttctcctgc tgcgtcatct cttgtctccc
    14461 caatgatttc atatgatcca tcttcttgca tatagactaa ttctgtatgt cctccgctaa
    14521 caagaagtgc catcaatgga aactggaatg gtttaaccag acgggctgca tagatatgcc
    14581 ctgccatatg gtttacagga ataagcggca attggtgtgc ccaagcaaaa gccttagctg
    14641 cagaaatacc aatcagcaac gagccgacaa gtcctggtcc ataagtgaca gcgactgccg
    14701 ataaatcttc tgccgacaca ccagcttcta ccagtgcatc ttccaagcat aaggtgattt
    14761 gttctacgtg atggcggcta gctacttcag gtactacgcc accaaaacgt ttatgactgt
    14821 ttatttgaga agcaacgatg ttagataaga tctctgttcc atttctaacg accgctacac
    14881 tcgtttcatc acaacttgat tcaatcgcca gaatcaattc ttcattcatt tcatcgtctc
    14941 cgtttttaac tttctgctca taatgatcgc atcttccgtc ggattgcgat aatatgattt
    15001 ccgtttacct aatatacgaa acttttctga ttcataaagt tttcttgctg cttcattaga
    15061 tagacgtact tctaaaaaaa catgcagcga atcttttatt tgttccgtaa tcagtaattg
    15121 taacaaatgc cgtgcatgcc cttttccttg ttctgaaact gcaacagcaa tatttgtgat
    15181 ctcgacttca tctattactt tcgagtatcc aataaagcca cagatctggt tatcttcagc
    15241 taaaagcaga taatcagagt gaggctgttg gatgtctgcc aaaaactgca ttttcgtcca
    15301 aggtgaacca tgtggataag cattttcgct aatcatccat acgcattctg ccaagtacgc
    15361 ttcatcaaaa tctttttttc tgcaaatcaa ctaatctcac tcattttcta aaagttttat
    15421 catatccaac gcatcttctt ttgtttcagt gtaatatctt tttttgatcg ttgttgcttg
    15481 aaaccccaat ttccgataaa gtctttgtgc atcttgatta ctcatacgca cttctaatga
    15541 catcgtctca cagcgattca ttatagcaaa gttctcgatt tcgtcaataa gcagcgaacc
    15601 gattcgttta cgctgatatg ccggtcgaac ggcaatattc gtgatatggc aatctaaacc
    15661 gaacgctctt gaaccgataa aaccaatcat tcttccatta tcaaagatac ctagatatag
    15721 atgaggaagc ggtgacttca attctgatat aaaggcactt tttgtccatg gcaattcgcc
    15781 attatagact tctcgttcga catccagcag ctctttgata tcttctgtag tcaattctct
    15841 tagtacgtaa cgacgatcga tttgttcgac tgttttttct gtataaatca ttttatcttg
    15901 aaaaaagctt ctggcatacg ctctaaattt tttcaacata actttcgtct ccaggtgtgt
    15961 gcgtctccaa ccatttttct tctgcttcta ctcgttttaa atagcgagga agaaaagctt
    16021 gtttctctgc aactggttca actaaagcac ctaattgagc cacagttaca ccacttggaa
    16081 tatcccatgc tggaactgta ttaatcatcg cactaggcaa tatttccttt atttcagaga
    16141 agaatttgtg acaatcactc ccgacgaaat aaatagcttc attcagcttt tgtagttgtg
    16201 tgaacaaatc agaagcagaa atatgtacat cttcaagtac agtttctaat ctattttctt
    16261 tccagcggta tgccccagcg tatacatttt ttcttcgagc atcaaacatg ggcacaataa
    16321 tattatccac accgatgcaa ttagccgcga tggttttcag actagatact cctactagct
    16381 ctttatctaa tgtataagca atcgtttttg ctgtcgttac acctatacga agccctgtat
    16441 aagaaccggg accatcagaa accgcgattc ggtcaatgtc ttttggactt atttgaagat
    16501 ctgcaaacaa ttggtcgatt gcaggcatca gtgttacact gtggttgcgt ttgatatttg
    16561 tttgtatttg tccaagaatt tgttcgtctt ctaccacacc gatcgccaaa gtttggtttg
    16621 cagtatctat tcctaatgta atcatatatt tgatcctttc tgctatgaca ttctcgcctt
    16681 ccattgtagc atactttttt attctgagga tgaaaatacc aaaggcaaaa ctagtacaat
    16741 aatacatgat tatctgctgg cgggcaaatt ttgccccttc ctgaaacaca aaaaagctgc
    16801 ggtatcactc cattttccca cagcttttcc atcttttatt tcgttgattc tcgaataatc
    16861 aactctgttt ccacaataat ctttcttgaa accggtgctt tggaattact taattgaaga
    16921 atcgtctcca ctgctagctc tcccatccat tcggtataaa cttttacagt agaaagcgag
    16981 ggcgttacat atttcgctac actgacatca ttgaagccca tcacagaaat atcttctggt
    17041 accactaaac ctttttcttg aatcgctttc agtgcgccaa tcgctaatgc atcattagct
    17101 gcaaaaagcg catcaggaac atgcggattc gtttttaaat actgcttcac tgcttgatat
    17161 cctgactcga cagaaaaatc tgcttcgata attggacctt cgtcgtagcc tttttctgcc
    17221 aaaacttgtt gaaatgccat aattctggga tcttttagcc gctgatggtt tttcttcgta
    17281 tattctgttc cagcaagcat agcgatatgt tgcgctttat gggagacaaa gtgttcaatg
    17341 actttttgaa cacttgactt aaagtcgaca actagagagt cgattccttg agaagtgccg
    17401 tcagaatcta ccaaaagcaa ggcattttgg gatcctttca tttctaataa ctgagcttcg
    17461 tcgaattttc ctagtgcgat cgttccatct gccggaagat cactaatgga atcccacgtt
    17521 tctttcaata aagtaacgtt tgcttcttct gccttttttt cgattcctag gcgaatagat
    17581 aaataataaa gatcttcaag ctcttccgta tcgtcgtacc actggatcag gcgaagcgtt
    17641 tgcttagtat ttgctgcatt tttacgatgt ttcgtataat ttaagcgttc tgctgcttca
    17701 aaaatttttt gctttgtggc taagccaacg gaaagatcag gatcatagtt gagaactctt
    17761 gaaacagtag caggagaaac tcctgccaac tgcgcaatgt ctttaattgt tgccatttgt
    17821 ctctcctcct tttttacgtt tataaaatcg cagtaaatcg ttcaaacgct gcctgtcctt
    17881 tttcatctcg cttgaatact ccagcgtctt ccagtacacg tgcaaaaacc tgacctacag
    17941 atttttgtac gacatcggtg accgtatctt tcgtcaaatc aggatgttct ttttttaatt
    18001 gttctgccca cggacgatga tattcagcca tctggttttc ttctcctaat aagaaatgct
    18061 ctacttctac tagttctggt ttcaaacgag gtggtaaaac agcaagcccc attacttcga
    18121 tcaacccaat gttctccttt ttgatatgtt ggacatcttt atgtggatga aaaatcccat
    18181 caggatgttc ttctgaaaca ttgttgtctc gaaggacaag gtccaactca aagtaattgt
    18241 cccttcttcg tgcaattggc gtaatcgtat ggtgtggtgt accatctgct gaaaaagctc
    18301 tgatagatac tgtttcatcc gaatatgctt tccatttttc caatactgag ttagctgctt
    18361 caataagcaa gtttttctct gttgattgca aacggatcac agacatcggc catttcacga
    18421 ctcctgcgat gacttgcgga taatcttcta gtttgataag tttttctatc ggtgcttttg
    18481 ccataggaaa ttcatgacgt cctgcctgat aatgatcatg agaaagaatc gatcctccaa
    18541 caattggtaa gtcagcattc gaaccaacaa agtaatgagg caagacttca gtaatccgaa
    18601 gcagtctagc aaatgtttcc tttgtgattt tcatcgggcg gtgttgttct gataaaatga
    18661 tcgaatgttc attgtaataa gcataagggg aatattggaa tccccagctt tcaccgtcta
    18721 gattcattcg aataatccgg tgattggtgc gggctggata gttcaagcga cctctatatc
    18781 cttcgttttc catgcaaagc atgcaggtag gatagtctac ttttaccgcc tcgcgttctg
    18841 ctgcgatttg ttttggatct ttttctggct tagataaatt gattgtgatt tccagttcac
    18901 catactccga ctctgccgga aatttgatgt tttttgcgat ggctcttgtt ttgatgtagt
    18961 catttttctt acttaaatta aagaaatact cagttgcttc ctctgggctt ttcgaatagt
    19021 gctgtgcaaa gaatgcattg acgactgaag gtggcggtgt gagaaaatcc attaattgcg
    19081 cttcaaaaat ctcttgttct gctggcaatt ctgaaagaac accattttct cttgccttag
    19141 cgacaagctg atccaataag tctacagatt cttccttaac tggtcttact tcaatgcttt
    19201 ctagagcatc ttctcctacc atccctaaaa gacgattctg taaatataag cggtccattt
    19261 ccatccatcc gccagcttcg atcgcaagtg tggcaaaatc acaaatcgtt tgactgattg
    19321 acatatctca ttcccctatt cttcataacc atttggatgg ctgacatgcc aatcccatgc
    19381 tgttttgata atcgctttga tatctgtgta ttcaggtttc cagcccagaa tctctctcgc
    19441 tttttcactt gaagcgacta atcggctagg atctccagct cttcttggtg ctatttctgc
    19501 tggaatttct tttcctgtca cttctctagc tgcttctagc atttccttga ctgagtatcc
    19561 tttgctgctg cctaaattga agaagttgct ttcatttcct tctttcaagt attccaaagc
    19621 taaaatatgt gcagcaatca aatcttctac ttgaacataa tctctgatac atgttccatc
    19681 tggtgtatca taatcgtctc cataaacagc caaggctttt ctttgaccaa gagctacttg
    19741 taaaatgatt gggacaagat gcgtttctgg tgtatgatct tctccgatag atgcatctgc
    19801 ttttgctccg gctacattga agtagcgcaa agcgacatag cgcatgccat atgcttggtc
    19861 acaccacttc atcatttttt ccatcatcaa tttactttca ccatacggat ttttaggatt
    19921 agctggtgta tcttctgtga ttggagactc tttcggctct ccataagttg ctgcagtaga
    19981 agagaatacg attttattca cgttgaactc gtgcatgact tcaagtaaga tttgcatacc
    20041 gtatacgttg ttgttgaaat acatcaatgg tttttcgaca gattctccta ctaaagagct
    20101 tgcagcaaaa tggattactc cttcaatcgg ttccttttca aatacggaac gtagaaattc
    20161 tttatcccgg atgtctcctt cataaaaatg agcatctgga tgtactgctt gtttgtgacc
    20221 tgtgagcaaa ttatctacca cagctacttg ataccccttt tgaactagct ggtctacagc
    20281 gtgcgaaccg atataaccgg ctccgcctag tactaaaatt gtcataaaaa acactccttt
    20341 gattagtaaa attgtgtttg ttgattctat ataatttaaa aaacgaagtt tacttttatg
    20401 gtgaaaacaa acaaagtaaa atttcgtaaa ttcatatggt aaatttataa taaaacattt
    20461 agtaaacatt ttcaaggatt ttttgcaaag gtttacaaac aaacgtaaaa ctagcctttt
    20521 tttctctttt gttccataat agatataaca aataataaat gaggtggatt caatgaaaaa
    20581 atttgtatct ggaatattag taggaagtct ggcaacagcc gctgccgttg ctggtttggt
    20641 tgcttctgtg aaaaaaacag tgatcgatcc aattgacgaa aaagaagcaa tgatcgaaga
    20701 aaaccgtaaa aaagcaatgc gtaaacgcgt ttctcgttaa taattattta aaaatacgca
    20761 tgaagacttt ctaaaaaaca gataagtcat catgcgtatt tttatttgtc agtcaatata
    20821 agttgtgcta ttttatctgc ctgtctcaga ttccatggat ctgtataagg tctagctact
    20881 gctgcagtta gccaatccac accttcaaca ggtattccat agcaataaaa gtcagactgg
    20941 atttcccctg aagcatcaat cacgcgattc gtacctcgct caacatctat agcttctgaa
    21001 tgataacttc ctgtattatc tgaaaatgaa aaagggcgaa caagtttgtt ttccttcaaa
    21061 ttttttatga caggattact tgaacgagaa aagcttgttt gtggcaatcg agcttcaatc
    21121 aaatagcgac tgctgatttc tttatcttgt agagaaataa catagcggtt gtgcttttgc
    21181 tgaatatcaa atggcggttc gatcaaatga aaaatacccg catctatcag tgctgctaat
    21241 tctttcgtcc gaatgattgg cggaccgatc gttaaaaagc tatttagatg agtaaaccat
    21301 ccccatagta tttctttgta ttccttagca gaaaaaacgt gccattcaat agcctgccgg
    21361 attggatcac gccagtcttt taatgcatca aatgttgaag caaatgctcc tgtgcaattg
    21421 cctttttccg cttcttttat ctgcccttca ataaatattc ggctagcttc tgaaaagggc
    21481 tcattctgat aggcaagagg agtttctaaa tacgaccaat cccatctata agggattagt
    21541 gctggatgct ttccgagaca ctcctctgaa gagagggaga gaaaatcatg ctcaaaattt
    21601 ttctttggaa tcggcaagtg atattcttcg atgattttct tgtaataaaa caactcaacg
    21661 tcttttttca gatagtcaaa aaatgtttcg ccagtcaaaa atcccgactg atgccattgc
    21721 tccaggtttt catttgttag taaccgtggc catgccattg ctccgccttg cttttgattt
    21781 cttcctcgag ggtaataagg gagccccctt cttgatccac tgtatacaat cggttccttg
    21841 cctgatggat gatagaccag ttttcccttt tcgttctcga agcgccctcc tcttgatact
    21901 gtaaacaatc cgacataatc aaaaaaactt aagcctagac ctcttaaaaa gacattttct
    21961 ttaggcggta tcttcgaaag atctacatct gcaggattag aaggaagctg atacagtaaa
    22021 acatttttct ttgcgtagtc tacccacact ctttcttctt ctgtctcatc attttcccag
    22081 tgaccgcttg ctaaaacaag ctgatcgata gaatagcttt gctgatctgt ctgtaaaaga
    22141 taaccatctt ttcttttgct tacttttttt actaaagaat aaacaaactg aatagaagct
    22201 ggaaattctt cttgcaactt tgagaaaaac cagcgttgat agagtccgta taaacatcga
    22261 gtagattgct gatctttttc cagacgattg atttcttcta taattagttg cttatttttg
    22321 gttaccgtct gttcgatata atctgtagca ggtcctttac tccattgaaa caagttgggt
    22381 ccctgtgtta ccaatcctcc actggacaat gtttcatctg taaaaagcgt cacttgttga
    22441 gaaacagaat tcattaataa ctccggtggc tgattcaacc gccaaactcg acctccagga
    22501 ccattgggat cgaaaagaaa aagttcaaga gaatgtctgt cctgattatt atggagaatc
    22561 ctttctgcta cacttaatcc tctaggtccg gcaccaatga tccctatttt catttgcatg
    22621 cctccatttc gataaatttt ttcaataaaa cagcatggtt ctgatgttca ttttttgcac
    22681 cataaacaaa agtaatgact ggatgttctt tcataagttg actgagttta aaaatagctt
    22741 gcttcttttc ttcttcgaaa atcaattctt gctggtattt ctttgcaaat gaagcaaatc
    22801 gttctggtac atggtcaaaa gttttgcgtg cttcattact aggtgcaatt tctttcaacc
    22861 acagatctaa ctgcgctttt tcttttgaaa ttcctcgtgg ccagaatcta tccacgagta
    22921 ttctatagcc atcctctttt tcagcatcaa ggtaaacacg ttttaatttg atcatagttg
    22981 tttccttctt tctacctttt cgcttagctt atatatgtag ataatagcac aaaataaaaa
    23041 aaatgaacgg cacaactatc cattgcgccg ttcatgtgat cttggtcaaa atctaatgat
    23101 tgattcggtt tttaaagctg tcatacaatc atctgtttta tactttttta cttttgattt
    23161 ttccagacca tccgtcatat ccacccttaa gtaaataaat ctcttgataa cctgctttac
    23221 gtaatttatt tgctgtacgg atgctcaaac ttttcttttg atcgtaaata tagacaggct
    23281 ggtcttttcg aatagatcct aatgaatctt tcaaaacagt gtaagggatg tttcttgcac
    23341 ctaaaatatg cccagcatca aacacatctt tttcgcgaac atcgattact tgtgcttttc
    23401 tcattccttc tcgaaattct tcttctgtca aagtcgttgc tgaacgtttg gccattactc
    23461 gtagatagac ttcccaaagg atgattgcaa gcacaatcaa tagcaaaatg atattaatta
    23521 cccataaaac catgtaatgc ctccgttttt ttaagcaaat ttcaaggcta atgaggcagc
    23581 accaatgaca ccagcttcat taccaagctc tgctaatttg atttttgttg attctcttac
    23641 ttgcgggaaa gtaaattctt taaaatattt ctctacacgg ctacgtaaaa attctcctgc
    23701 tgccgatact cctccaccta acacgatact tgacggattt aatgtattcc ccaagtttcc
    23761 gcaagctaaa cctaagtaga agcatacgcg atcaacaacc atcaatgcaa acggatcgtc
    23821 ttcttgagcc atttcaaaga tatctttact tgttacttct tctccgttgt ctagcattgc
    23881 tttcagtttt gaatcccctg cgtattcttc tgccaagaaa cgacctaggc gtaccacacc
    23941 tgtagcgcta gatacagttt ctaaacatcc gcgtttaccg caagtacatt cgaacccttc
    24001 aggatccaca gtgatatgtc cgatttctcc tccagctccg ctcacgccgt gaatcaaatt
    24061 tccgccagca acgatacctc cgccaacacc tgttcctaga gtaacgaata caacgtctgg
    24121 atcgttttct ccagcacctt tccatcgttc acctaaagca gcaacattcg cgtcattatc
    24181 gatagcgaat ttgattcctg ttcctgcctc gatcagtttt ttcacaaatt gaacttctgt
    24241 ccagtttaag ttatacgcac caataaccgt tccagcttcg ctgtccacgc ttcctggggt
    24301 acccatgccg attccgataa agtcttcggc tttcatatta tataaattca aacgatgatt
    24361 gattgattca atgatttcag gaacgatatg cttaccatca tccaaaatat tggtatcgat
    24421 gctccatttt tgctgaatct ctccttctgg tgttaaaatt gcaaattttg ctgttgttcc
    24481 acctaaatca atcccaataa tcttcttgtc cattacaaat ttcctttctt tcggctttct
    24541 tcaattcggt gctctctttt taatatgcgc cacgctgtca tgtatgtatc atgatcaatc
    24601 aaacggctat catacagatt acgcaattcg atagtcatta attcaatgtc atagatgcgt
    24661 gcacccacat agataaagat gccaaatttt ttgaacagct gctgtacatc atataagctc
    24721 tccatcttta agcacttcct tcatattata caagtaaacc atattttttt aaacccagta
    24781 aaatacatat tacaaaaaga aatacaaaaa ctagtgtaga aagaatcctt tggtgtatcg
    24841 aatagcttgt ctgttgtttc ggtagaccca aaacattccc taacactaat ccgccaatta
    24901 gcccaccgac atgtccccaa acatctacag aggtatccag aagaccaaaa acaaatgtca
    24961 acacaataaa taaaagaaaa tgtctgacta gctgctggat cgctgggtta tgtttaaaat
    25021 gaaaccctaa gataaacaac gcaccgaaca aaccgaatat cgaagtactt gcaccaccag
    25081 acagaacatt cgcttcgtta aaagcaaagc ttgctgtatt tcccattatc ccgctgaaca
    25141 tataaatcaa gaaaaaacgc caatggccat agattgcctc gatttgctgc cccataaaat
    25201 acagtatcag tgagttcatt acgaaatgca tcagtccaaa atggatgaag attggtgtca
    25261 ctaaacgcca ccattcattg aagtgaacaa gataaggacc atacattccg gcataataag
    25321 ggatctcaag tcgcggaaat aattccatca tgaggaagac cgctgtctgt atccctaaaa
    25381 aagcataggt ccataacggt cgtcttaacc atacacgcaa ttttatttgc tgttgataat
    25441 tcatgaaaac ctcccatttc attttagtca ataaacaatt gttggatctt ctgatcaaag
    25501 ctctccggtt gccattgttc attcaattgt tcacgaaaaa caaggctaca tgttttttta
    25561 tgaaaattat ttaaataccg gtcgtaataa ccaccgccaa aaccgattcg ataaccggct
    25621 ctattgtaga taatacctgg tacaatgagg agatcgatca tctccggcaa atagagcttc
    25681 tctgattgtg gctcaagaac accaaaactc gaacgtacaa gaacggactg ttcatccatt
    25741 tcataaaacg ccatctgacg tttcggcaaa gttttaggta caactatttt cttttgttct
    25801 ttttctgctc gttggataac cggctgtgta tccagttcaa attcattcga taaagtcgtc
    25861 cctatcactt ttgctgactt ccagtactcg ctggcgaata gctgtttata gattcgctgt
    25921 tctttttcct ttttcttgcc acttttggcc agatttttca gcttttcgat tcctttccgg
    25981 cgtaatctta ctttcaattg gtccaaaaac tcacccttcc ttctctcata aaatggtata
    26041 ggaaaaaaag aaaaatagca atcgaacttt caaataaatg cataaataga ataaaaagaa
    26101 gacctagaaa tgattggcct tcctttttta atgaatttca actgttcagc gcgtgttttt
    26161 gtctgataaa aagtgcatac agaaaatatg gcgcaccaaa aagggcaatc aaaattcctg
    26221 taggtacttc cccacttagt agaatcactc tagcaaccat atctgcacta agcagaaaaa
    26281 tggaaccgaa caaaccgctc agaacaaagg tccagttatt ttctttacgt acgactagct
    26341 tcgcagcatg aggagctagt agtcctacaa aagataaact acctgtcacc gctacactac
    26401 cgcttgccaa agcaacagct aacaacaaaa ggattttttg acttttagcc acgttaaggc
    26461 ctaatccttg cgcgcgttct tgaccaaatg atagcaatac aatcctctgt gcataaagtc
    26521 ctcctagcgg aattaagata accgcccatg gaagcaatgc ccaaacataa ggccagctcg
    26581 caccccagat tgatcccgct aaccatgcat tcacaaatcc ataattttcc ttagataatt
    26641 ggatcgtgca tagcaatgtt aatgcagaaa ggccggcatt aacggcaata ccggacaata
    26701 agattcgatt catacccaaa aagccatttc gatcataggc cgcaagatag acacagcaag
    26761 cagctaaaac accacctaga aaggctacaa ctagcaatag aaacggcagc gaatagtgcg
    26821 aaaagaaacc taaataaagc atcactaaaa atcctgctcc ggcattaatg cccaatatac
    26881 tagaatctgc caattcattt cttgttactc cttgcaagat ataaccagaa acgccaagac
    26941 aagctcctgc taataaactg atcagtaatc gaggaactcg aaattctcta acaatcagcg
    27001 ccaaagaaga tgattctttc cctatgaacg tggcaaaaag ctgatccagg taaataaaag
    27061 gcgtaccaat cattaaacta cctatagaca ggatgacaag tacaaaaagc aagaaataga
    27121 acgtccaata tatttttttc accgttgttc cctccttact tgtatcagta aaaacggaac
    27181 gccaatcaat gcaatgacta atccaaaagg tgtttcaaaa gggggattga tcatcctcgc
    27241 tgtaaaatcc gccaacataa ccaatccacc gccaactaaa aaagagacag gtagaacata
    27301 acgatagtcc gttccaacca ttccgcgaac aactggcgga accaacagcc caataaatga
    27361 aacaggtccg actaacgaaa cggcaatggc tgctaacact gcaactagac agaaaacaat
    27421 caaccgcgtt cgtttaggat gacttccaag agctaatgca tgtgtttcac tcaaatgaat
    27481 caaagatatt gcttttccta atgaaaaaga aaccaaaaca gcaagtatat ataaaggaaa
    27541 caatactgct aattgtttcc atgtgatatt ggcagctccg cctacaaacc aaaaagcaag
    27601 atcctgctgc agattaaaga attgggtaag tgcttggctg atagcagtaa aaaaagaact
    27661 aatagctacg ccagctaaaa tcagctgtaa aggattcatg cccattttcg aaaactgcaa
    27721 aaaaccaaat acgagcaaag ttacagcaaa agaacctgcc aatgacatta gaaacacaga
    27781 aaaatcagaa gctttaggcc aaaaagcaaa actaagggcc attgccaacg aagcacccgc
    27841 gttgattcct agtaagcctg aatctgctaa aggatttctt gtcactcctt gcatcaatgc
    27901 accgctcaat gcaaaacaac tccctacaag aaatgctccc gccacacgag gcaaacgaat
    27961 atttcgtatg atttggtgac tttgttttga tctatcaaaa tcaaacaacg cctgccaaaa
    28021 atctgctttt cccacagtcg ctgcgccatt tgaaagagca acaaaaaaaa taatcaaaag
    28081 aacaaaacag accaaaagca ggagtctatt tttcttcata gtcctcataa ttgatcctcc
    28141 tgctcttttg gcaacaaatc ataggttaga aaaactggtt tatttgttct tggaagcgtg
    28201 acaatcgttg catcaatctc aaatattttt ttcatacact cttttgtgat cacttcttca
    28261 ggtgtacctt ctgtgatcaa cttaccgttt ttcattgcta ataaataatc tgaaaaacgt
    28321 gaagcatgat taatgtcatg aatcgacatc aagatcgttg tttgtttcat ttgattgatt
    28381 tcagtcaata actgtaggat ctctaattgg tgtgccggat ctaaaaatgt tgtcggttca
    28441 tccaagatca agatatctgt ttcctgagca agcgccatag cgatccagac acgctgggtt
    28501 tgtccaccag acagcgttgc gatatcccgc atacgaaatc cagctagacc tgtagcatcc
    28561 aacgcccact cgattgcttc atgatcttgc gtgtccatgc cactgaacag tttttgataa
    28621 gggtatcgtc cgtaagatac tacttcttct actgtcatac ctgtagggtg ttcactagtt
    28681 tgtgctaata atgcaatttt ttttgcaagt tcttttgaac tgtatgtaga gatatcagag
    28741 ttattgacaa tgatctttcc tgatttcaca ggtagtatac gggtaaaact tttcaataaa
    28801 gtagattttc cacttccatt tggcccaatc aaactagtga ttttcccttc aggaatcgta
    28861 acagacatgt tttcaatgat ttttttgttt tcgtagccgg ctgcaatgtc agctgctctt
    28921 aatctcgtca tttcacccat cctttcgctg aaaatcattc tcaattatga cgctgtttca
    28981 acatttcgtc aagcgctact ttcatatcta tagccaaatg aagcggttga cagcgttcga
    29041 aatatcagga ataataacca atgagaaaga ttctcaatta tgttaggagg aaagaaatga
    29101 aattaaaaac aaaagtattc acattatcta gcatattgct gctggctgga gtactgagcg
    29161 cttgctcccc ctcttcagat aaagaaacag ctacaactgc caattcgacg acttcatcca
    29221 atagtactca tacagtcaca gatacacttg gacataaagt agagattcca aacgcgccca
    29281 aacggatcat cggcagttac ttagaagact atctgattgc actaggggaa aaacctatcg
    29341 cccagtggac tgttggcagt ggttccattc aagattatct gcaagatgat ttaaaggatg
    29401 tcccaacgat ttcttatgac cttccttatg agaaagtgtt aagctttgag cctgatttgc
    29461 tgttgatttc ttcttccgct actgtcgaag gcgggaaata cgaacaatat agcaaaatcg
    29521 cgccaactta tgttgtaaaa aacggaacag atgtcacatg ggaagaacaa ctaaaagatg
    29581 tcggcaaagc tttggcaaaa gaaaaagagg cagaaaagat catttccgat tatcaaaaat
    29641 ccatcaagaa aactcgagaa gaactagcag ataaaatcga gaacaagaca gctgcagtgt
    29701 tgtgggtgac caacaactca gcctttatgg tcagcaaaaa tcggtcaagt ggaagaatcg
    29761 tatacgacga tctggaattt ggtgttcctg atctagtgga agaggtctcc aaaaaagcca
    29821 cttctgactg gtctgctgtt tcctctgaaa agctagctga attagatgct gactacatca
    29881 tccttgtgaa cagtgacaaa gatgctgcca tgttcaatga accaagctgg aagaatctta
    29941 aagcagtgac agacaatcat gtactgcaat tcggacctga atctagttgg ctatataacg
    30001 gacctattgc cagtcaggaa atggtcaatg atatcaaaga aaaactaaat tgattttaac
    30061 taaaaaaagc atcttcacga ttagtcgtga tatgcttttt ttcttattaa caaactagac
    30121 gcatagattt tattcttctt ttgaagcaac cctatttttt actctttccc atttttgaaa
    30181 acgatgggca tatagatttt cttgatccgt tatcccctca tactcctcta taagggcgaa
    30241 gtctgaaaaa tcaatattcc caatatacgt atcgccttca aacgtgctat cgatcaatgt
    30301 tcgccagatc cgaccagtgt aaggaagaag ttcttgaaaa atccgactac cacccgaaac
    30361 atagatatct tctgagatcg tttgactata cgacaaaagt tcatcgatcg aatgcattac
    30421 ttccgcattt tctttcgtgc gaaaatttgg ctgcgttgtc aacacgatga tatggcgata
    30481 aggaagtgaa agatccccca ttccttcata ggtctttctt cccatcacta aaattcgatc
    30541 cattgtatgt tcgcgaaaga aacgcatatc atttggcaat cgccatggta acaaaccatt
    30601 tttgccgatc agaccatttt tatcttgtgc ccacatggaa ataaacatat tatccgctcc
    30661 ttatgatttt agatgttttg agataaaaaa agtctcaatt ctttgaccag caaggaattg
    30721 agaactttaa aaacattatt ttgtttcacg gtgcaaagta actttgcgtt cgcgtgggca
    30781 atatttttgt ttttccaaac gatcaggatt gttacgtttg tttttgcttg ttagatagtt
    30841 acgttcttta caagaagtac actctaaagt gatgtttacg cgcatgtttt tccctcccat
    30901 ttttacaaga atcctctaag atgactctca gacttgatta tcttaccatg attttttcta
    30961 gattgctagt gtttttcacg attttgttaa gtaaaactac ttgacgataa atacaacggt
    31021 tttacttctc aaacaaaatc tttttctttt tgtataaata cccttacact tgtttatata
    31081 gattatgttt tttaataaag ggggatacta atatgccatg gaacatgaag gactttcctg
    31141 catcaatgaa aaacttagat aaattgacaa gaaaaaaagc aatcgacatc gcaaatgcat
    31201 tattagatga agggtaccct gataaccgtg cgatcccaat tgccattgat caagcaaaaa
    31261 aatggtatga agatgctagt gaatcagaaa aacgaacttt cgaaaaagaa aaaaatccaa
    31321 gcaagacgga tgaacacgat acgaatcctc gtgctggaaa actgcttgat tcagatgtga
    31381 tcgtagaata tgaggaagaa caatggatcg tgaaatctaa aggggcaaaa aaggcaagca
    31441 accattttga tacaaaaaaa gaagcaatcg aaaaaggaaa gcaagtagca caaaacaaag
    31501 aatcaacttt gttcatttat aaaaaagatg ggacaaaaga aaaagaaatc gattattgaa
    31561 catatgtaaa ggggttgtga cgaaaatcgt gtcacaaccc ccttatgttc gaaacaatgg
    31621 tgttcctctg ccaactccga accataagtc ataatatcta taaaacggga agagctgttt
    31681 tttgaaattg tttcttatca ctcagtgtta aacggtagga gaaaacctct tttttattga
    31741 tatttgattt tcatcaaaca gtcacatagt cgattgcttc tgcttgcgga atcgtttcat
    31801 ctacaaagta gactttatac catgtcaaga aactgaagat tgtccagatt tttctttgct
    31861 cttctttacg tccttcgtga tggtcatcta gcaacttcat gattttttct tgatcaaaaa
    31921 attcttttgc aaaatctgct tcgaacaatg ctttgacttg ttcgtagccg tgttcttctt
    31981 tcaaccaagc tttgattggc acagggaatc ctaatttcac acgattcgac catttttccg
    32041 gaagatgttt gttcgcagct tgtctgaaaa tatcttttgt gttgttttga ttcaataaaa
    32101 acttacttgg tatttgttga gccaatttca tgacttcgat atccaataaa ggtactcgga
    32161 cttccaaaga acttgccata gaaagtttat ctgcctttaa caagatatct tttggcatcc
    32221 attgatgaag atcgacatat tgcatcttat tgacttcatc tttgattcct tctgttttct
    32281 cgtaatgaac agtcatgatt tcatccacag atggtgctgt ttgatatttt ggtgttaaca
    32341 cttctgatgc ttctgattct tcgaacactc gagcatgacc gataaaatat tcttttgcag
    32401 gagcaagtga ttcatataaa tggatccgtc catggaaatt tttcattttt ccgattttac
    32461 gtcctaaatt atagcgtgtt ccttttggta attttttcaa tccttgagca atcacacgga
    32521 tgaattttga attcgtatgg aatccatacg tttggtatcc cgcaaacagt tcatccgccc
    32581 cttctccaga ttggactacc cgcacacttt gtgaagcaag atttgctaaa aagtacaaag
    32641 gtacgcaaga aggatttgaa tcaggttcat ctaagtgata ctggatcaaa gggaatgctt
    32701 tgaacgacat gtctccgtcg atcactgctg ctgtattatc taagtccaat agttcggtta
    32761 gttttctggc ttcaatcgct tcattatagg ttttatcatc aaacccgatt gagaaagaat
    32821 gatctggttt caatacagag gttacataac tggaatcaac cccgctggat aagaaagaac
    32881 caacttctac atcactgacc gtatgtgctt caatagaagc ttgaacggtt tcgtcgattt
    32941 tttcgatcca ttcttgtcgg gaatgcgttt cttttgtttc aaaatctgca tcccaatatt
    33001 gctgaatgtc tatttttcca tctttatacg tataataatg gccttcaggc aaacgataga
    33061 catctttgaa gaatgtttcg ccgtttaatg gagaatattg gaaagtcata taaggtttca
    33121 acgcttcttt gttcaattct ttgttaaaat caggatgagg cagaaaactt ttgatttctg
    33181 aaccaaacat aaatgttccg ttcatttctg cataataata tggtttgatc ccaaagtggt
    33241 ctcttgcacc gaataactca ttcttttcat tatcccaaat agcaaaagca aacattccgc
    33301 ggatcttttg caataattct gttccccatt cttcgtaacc atgcaaaagg acttctgtat
    33361 ctgcatgtgt ttgaaaaacg tggccagctg caatcaattc ttctctcaaa ggctggtaat
    33421 tatagatttc gccattaaaa ataatgatct ttgtccgatc ttcattgtaa ataggctgag
    33481 taccgccctc taagtcaata atacttaatc ttctgaatcc taaagcaaca tgtttatcga
    33541 tatattctcc tgaactatta ggtccacggt gaacgattcg atccatcatt gtattaataa
    33601 ttgttttttt gttgtccttg tcgttaacaa aacctacaat accgcacatt taactttcac
    33661 atcctaatat aaaattactg tttatttcat tcatatgcat cttatcatag aataaatagc
    33721 ggacgaatat tttctctctt acaatttcgt cacgtgaaaa caaaagatga aagtttctgt
    33781 ttttacagaa aataaagtcc caatatctaa tttaccatgt tttctttttt gaggctacct
    33841 tattctcttc gtgttaaaaa aatattagtg gatgctattt ccaaaaaaac cagcaaaaaa
    33901 agacacgacc taaagatcgt gtctaattat gactgtatca gaaaatatga taccaaacgg
    33961 atctattcat taattaattg acatagttta tctgttgctc ttttatgact ggataactga
    34021 ccaattcatg acgatccaag tcttctttat tcatatttac agcagtaatt tgactgtctt
    34081 catacgtacg ataataataa atccctttat caacgttaca gcaagaagaa taaatcgtat
    34141 attcgtattt tctttctcca gtatcgcata ctcctttttg ttgctcgact gagcctagta
    34201 tatgaaaaaa ttgactgata ctttcagatt ctgaatcacc tgatgcagca ttcattttag
    34261 taaatgtggc ttttacaaat cgagaaacag aagagagatc tccaggtaag cccaatcctc
    34321 ccatcccacg actataaaca ttcaagctga tctggtttga aaaatgattt tctggtgttc
    34381 catttgatag cgagcgataa ttgttcagat taaataattg ataatcaaat ggcggattat
    34441 ttgtcaacac accgacagga ttatcatata aatgaagtcc atctttcata ctttcaatta
    34501 ctatcgattt ttctttatca gctaataacc agtgtaaagg tgacaagggt agtttttcac
    34561 taaaatcgat attgactaga ttgatagtag ccaataattc tttagcttcg tctatggttg
    34621 agcattgccc tagtatccat ggaataaact caaatggtgc aacgttatct tttccttctt
    34681 gtaattcttt ataatcagca ttgccaggaa aattcagtcc tgccatactc aacccttttt
    34741 catttgtagc ctcataatag agtggatagt tggatacccc agctgctatt cctatcattg
    34801 cataatgttt atctaaattt tttacctttc taaaatcgaa acgataattt cttggagtaa
    34861 tagtgaccac ttcattataa gacatctcat aatcaaaatt ccttccaaaa taatggtctt
    34921 tcgttgcata agtgattgcg gtacacatcg tttcccctcc taaaacaaat cgtttttaca
    34981 cttttatctt acatctagta ttttttttat caaaaaaagg ccaaagaaga ttgatttact
    35041 agcatttata aaaaatagta ctcaggggga atcaaaaaat attgtaggtt aaaagtacaa
    35101 caataagggg ctgtgacaaa agtcttgtca cagcccctta ttccgaacaa acggtgttca
    35161 aaagcttgca tctgcggtaa taagcccaat caaacgaaaa aataggaaaa gctatttttg
    35221 tttggccgtt cttattactt gatgcaggac agcttcttca caacctctaa tctttgatat
    35281 aaggaaggta caggatttga acctgcgcgc cggtattagc cggttcgccg gatttcgagt
    35341 ccggtgcatt accactctgc caaccttccg taagtactat ttttaaactt ttttcacgaa
    35401 atgtcaagcc tatttctaat agataaataa cagaaatcgc tttttttagc aaaaaagtcc
    35461 attgacagtt tgcagccaac ggacttaccg atcaaattca tactgataga acactatctg
    35521 attatttcag gattatctaa tgctaaaatc gagtcaattg tccgtttgat cagtgcaatg
    35581 atttgttctt ctgttggatg catgatgttt gatgacatca atgacgctaa gccagtcact
    35641 gctacccatg taccagtatg cagagcatcg acatattcat ccgataattg attgtatctt
    35701 tcatcttctt taactatttc acggaaataa ttgtatgaaa aatcatgcat tttctttccg
    35761 tccccatgtt catcaatgta caatgccatg taaagactat gatgcttttt tgcaaagtag
    35821 atatagttca aaccgagatc aatgatttta tcaccagtac gttcaatagg gaaaacatct
    35881 tcttttagtt gttcaaagat agaatccagc aacgtatttt ttaaatcttc catgtttttg
    35941 aattccagat aaatcggctg tgtcgaaatc cccatctttt tagcaatatt tctcgcagta
    36001 aatcctttaa acccttcctt tgcaacaaca tcataagcag cttttagaat ttgatccttg
    36061 gtatagactt ttcttctcat taaaactccc ccacttcttt actgcagtat atgttgtttt
    36121 attgtaccct atttttagca ttttttgcaa acattttact caaaacgtta tattttaaat
    36181 tttttttcag tcttctttaa cttttttttg caaaattaaa aaaatttggt taaattcaat
    36241 gggttccctt acatttttag ttttgaccta aatgatagtt gtccaaatct ttcatttcaa
    36301 gttatagtta aagaaaatga aaaagaaggt gtgtaatgga aaacgaaact gacgttattt
    36361 atattcatcc tcaaaaacga atcgtttcac agaaaagaaa gtatttttat cttggtttta
    36421 caggtgtttt ttttcttttt attggcttgc tttctaatac tcctactgat aattggagtg
    36481 gattgctaac tattcttacc tcgccaagca atcttttgac agattatttt gctttaggcg
    36541 gtttcggaag cgcattcata aatgtaggga ttttgacctt actttctgtg cttttagctt
    36601 atcggcacaa ggtgatttta aacggtccct tatttgcttc gattctaaca gttaccggtt
    36661 tctctttttt tggcaaaaac ctttataatt ctatctcaat cattttaggt gtgtatctat
    36721 acgctgtatt tgtcaataaa cctttttctc agtacatcat gatcggactg tttggtagcg
    36781 cattatcacc ggtcgttagt tatatcactt ttggtatgcg ttttccttta ctgataggta
    36841 ttttattggg gaatttagct ggcatagcaa ttggtctact tcttccgccc ttagctgctc
    36901 aaactttagt tttccatcgt ggattcacac tttataatat tggattcacc tctgggttga
    36961 ttgcgatgac ttttactgct gttttgaggt tattcagcta ttcaatcgtc gaaaatacat
    37021 tggttttcaa tgaatatcac tttcctctca tttggattat ttttggcttt ttttcgctga
    37081 cagtcggaat tggtttctat tataattcct ttcggctttt ggggattcga gaaattttcg
    37141 attcatctgg aaaattgaca actgatttca ttgctaattc tggtattggt gctactttga
    37201 tcaacatagg cttagttggt ctgatgctgt cttcttatgt tttgctggtt ggcggtcagt
    37261 taaatggacc tgtcatcggt gctattttat ctgcggtggg tttcagtgct tttggttgtc
    37321 atttaaaaaa cagttttccg atactagtcg gaatatttat tgcttctttg tttggaactt
    37381 ttcatgagat caccagtact ggcatgcttg ttgcagctgt gtttgggaca ggtctcgcgc
    37441 ccataagcgg tttttacggc agtttttacg gtgtaatagc tggtgtacta catattgctc
    37501 ttgtccataa cgtcagcact ttgcacggag gactaaatct atataacagt ggtttttcaa
    37561 ctggtttcgt tgcaggtatc cttgtaccga tactagataa ctttaccgct gtcagaaagg
    37621 aaaaaaagac acttggaaaa agaattatca aaaagaatca tcgatgagct tcttacttat
    37681 ttatattccc atgaaataac tgaaatacgt attggagtag aatttgctga ggaagggctt
    37741 ttcatagaga tacagggtac ggcagaaact cagccagaag atttagatgt acttgctgat
    37801 ttgctgaaca atcctcggga ccctagtatg gaaatctatt atcaagaact attaggtaat
    37861 ccccgacatg atcgggaaga ttatcatctg ttaggtagtt tgattgatga cgtggaaatc
    37921 atgtatgccc agccgattat caatattaag atctttcgac gtgcttctca ttcctattat
    37981 taaccctatt ttctatttat aaaagactga atcaaaaaag cagctcctga aagttcgatt
    38041 aaaatctact ttcaggagct gttcaagctt gacattattg attttccaat ccttcataca
    38101 cttcatctgt tacaggttct aaaaactctg aattaccagc agtgatcgcc aaatgttcaa
    38161 accaactgtc ttttgtcgca ccatgccaat gtttaatccc tttgtgcgtt acgacgacat
    38221 ctccagccat taatcgtctt gctggctttc cttcttcctg ataccagcct tctcctccgg
    38281 tcacaagtaa gatttgatag ccgtctttat ggacatgcca gtgattgcga caacctggtt
    38341 caaaagttac attacctaca ccaacagaaa cttcgggatc attcactaac atattcagat
    38401 agctttaccc ggtaaatact tgagcgtaag cttcgttttt ttcacctgct ggaaaaatca
    38461 cgccattgtg tatttcttcg tgttttgtcg tcatttacgc ctctttctta tcttcgctat
    38521 tttcttctaa atagatttct tttgctaaac taaaagctga ccaagctttt ggccatccta
    38581 cataaaaagc taaatgggta atgatttctg ctatttcttc actagtaatg ccattttgct
    38641 tgccaatctt cagatgagct ggcaattgtt caaaatttcc tcctgaaatt aatgcagata
    38701 tggtgatgat actacgctga tgagcagata attcttctct ggaccatact tgtccaaata
    38761 aaacatcatc attcaattct gcaaattttg gtgcaaaatc tcctaattga tctcgtcctg
    38821 cggtttgttt ttctgccatt tctcttattc tcccttcacg actgttaggt gattcaacta
    38881 tggttctaag gcaactttat tttctattgt ttcttcgcat ttcattttaa atgtagtctt
    38941 tcagcctgtc caatgcttag tttattcagt cgatatgct
//
LOCUS       DBBGRF010000024        38164 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000024 DBBGRF010000000
VERSION     DBBGRF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 38164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.024"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..812)
                     /locus_tag="ACIZD4_001395"
     CDS             complement(<1..812)
                     /locus_tag="ACIZD4_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HGC5990339.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDQTNQQIGDLGKLKKMYSNSIDFGGYDYSGNPNL
                     LSKLSYDLIENQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLP"
     gene            complement(830..1654)
                     /locus_tag="ACIZD4_001396"
     CDS             complement(830..1654)
                     /locus_tag="ACIZD4_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990340.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVNSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            complement(1658..2707)
                     /locus_tag="ACIZD4_001397"
     CDS             complement(1658..2707)
                     /locus_tag="ACIZD4_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990341.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGVDEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            complement(2704..3576)
                     /locus_tag="ACIZD4_001398"
     CDS             complement(2704..3576)
                     /locus_tag="ACIZD4_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage distal tail protein domain-containing
                     protein"
                     /protein_id="HGC5990342.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSESVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            complement(3577..7425)
                     /locus_tag="ACIZD4_001399"
     CDS             complement(3577..7425)
                     /locus_tag="ACIZD4_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HGC5990343.1"
                     /translation="MAGKGQPAGNIKLGISLDSTSFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKEIEDFGDKSTRSARKLDGLKDKLSSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIEKIGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NNVSDVIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGAEPLQEWDVPQYATGTPAGGHPINGPMMVNDGRGA
                     ETVITPDGRAFIPKGRNVVLNAPKGTHVLTAEETAQLQGSKAPKYRYKKGTNFFGNMW
                     DSVKKVAGNVGHTIKNVVGDVWDFISDPGALARKVLGGLDVLGGLTKYPLEVGKGILS
                     KATSALTEKITGLFSSGNLDTSVGTNGVYKYLADVAKSVMKKFPGFVATSGYRPGDPY
                     SHGKRNAIDIALPGVTGGSPRYTEAANYAFDKFASKIGYVITNGKVRDRSGQSGQPAT
                     GAWEPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTA
                     NLNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFD
                     PLSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAK
                     RSRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKG
                     NSRTDRDLALDIQKILVRRM"
     gene            complement(7425..7616)
                     /locus_tag="ACIZD4_001400"
     CDS             complement(7425..7616)
                     /locus_tag="ACIZD4_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990344.1"
                     /translation="MDQIYKDLIEAGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            complement(7640..7951)
                     /locus_tag="ACIZD4_001401"
     CDS             complement(7640..7951)
                     /locus_tag="ACIZD4_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990345.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     K"
     gene            complement(8076..8636)
                     /locus_tag="ACIZD4_001402"
     CDS             complement(8076..8636)
                     /locus_tag="ACIZD4_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HGC5990346.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGANVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLTKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEGMTLQKFKDLVNNKEGE"
     gene            complement(8652..9023)
                     /locus_tag="ACIZD4_001403"
     CDS             complement(8652..9023)
                     /locus_tag="ACIZD4_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990347.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EISGNYEDFASNNPLTIQFNVQVDVWVSTMKEVDAFYFALDEVMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            complement(9020..9415)
                     /locus_tag="ACIZD4_001404"
     CDS             complement(9020..9415)
                     /locus_tag="ACIZD4_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HGC5990348.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEELRQNT
                     PYWDGTKSNGKRGSYMQEHAKNHVVTSSIKNGLVEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            complement(9412..9747)
                     /locus_tag="ACIZD4_001405"
     CDS             complement(9412..9747)
                     /locus_tag="ACIZD4_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HGC5990349.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVPTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            complement(9751..10077)
                     /locus_tag="ACIZD4_001406"
     CDS             complement(9751..10077)
                     /locus_tag="ACIZD4_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HGC5990350.1"
                     /translation="MILDPKMDLGEIKNALKIDTDDDDVEVSRAAQAAIAYIRGAIGN
                     DKPSFYKQENETVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKASYL
                     LFVEEE"
     gene            complement(10092..11285)
                     /locus_tag="ACIZD4_001407"
     CDS             complement(10092..11285)
                     /locus_tag="ACIZD4_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGC5990351.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRRFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     ITPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSKWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIVNVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTTIANE
                     TPAKV"
     gene            complement(11282..11959)
                     /locus_tag="ACIZD4_001408"
     CDS             complement(11282..11959)
                     /locus_tag="ACIZD4_001408"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HGC5990352.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGINCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAEAPQEETLLQKKLKA
                     LNGGKNE"
     gene            complement(11994..13214)
                     /locus_tag="ACIZD4_001409"
     CDS             complement(11994..13214)
                     /locus_tag="ACIZD4_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC5990353.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDVEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALVKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGSNEGLKVKFASNMDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGNNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTTSSKSVAENG"
     gene            complement(13230..14582)
                     /locus_tag="ACIZD4_001410"
                     /pseudo
     CDS             complement(13230..14582)
                     /locus_tag="ACIZD4_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
     gene            complement(14769..15530)
                     /locus_tag="ACIZD4_001411"
     CDS             complement(14769..15530)
                     /locus_tag="ACIZD4_001411"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGC5990354.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENFDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            15623..15781
                     /locus_tag="ACIZD4_001412"
     CDS             15623..15781
                     /locus_tag="ACIZD4_001412"
                     /inference="COORDINATES: protein motif:HMM:NF024064.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HGC5990355.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
     gene            complement(15821..16261)
                     /locus_tag="ACIZD4_001413"
                     /pseudo
     CDS             complement(15821..16261)
                     /locus_tag="ACIZD4_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
     gene            complement(16248..16769)
                     /locus_tag="ACIZD4_001414"
     CDS             complement(16248..16769)
                     /locus_tag="ACIZD4_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HGC5990356.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            16871..17035
                     /locus_tag="ACIZD4_001415"
     CDS             16871..17035
                     /locus_tag="ACIZD4_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HGC5990357.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGQEVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            complement(17192..17509)
                     /locus_tag="ACIZD4_001416"
     CDS             complement(17192..17509)
                     /locus_tag="ACIZD4_001416"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HGC5990358.1"
                     /translation="MKEVRPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(17510..18055)
                     /locus_tag="ACIZD4_001417"
     CDS             complement(17510..18055)
                     /locus_tag="ACIZD4_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5990359.1"
                     /translation="MHMHIGEKIYKLRRLNNETMNDLVKQTGVSKSWLSDIESGKKQR
                     VDFNKICAIAKHYKVSLEYFRDDYLDSDEHEDIIPLTGETRVKSVKSLEQSLKYLNNK
                     QEPNLLEIKLKDTDSVPEVWYKGERLDELPKGLVDVSYHWKTDDFTNDDRGANDITIQ
                     YFSSFNDKYPDKKTIGHKRDM"
     gene            complement(18240..18470)
                     /locus_tag="ACIZD4_001418"
     CDS             complement(18240..18470)
                     /locus_tag="ACIZD4_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990360.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMLREAT
                     PNEVDKCKLIYCGHGYWKDEYIQQNIERWIDR"
     gene            complement(18467..18631)
                     /locus_tag="ACIZD4_001419"
     CDS             complement(18467..18631)
                     /locus_tag="ACIZD4_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990361.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKENNEV
                     ISFRRRRKAK"
     gene            complement(19251..19664)
                     /locus_tag="ACIZD4_001420"
     CDS             complement(19251..19664)
                     /locus_tag="ACIZD4_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HGC5990362.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            19867..20118
                     /locus_tag="ACIZD4_001421"
     CDS             19867..20118
                     /locus_tag="ACIZD4_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990363.1"
                     /translation="MTMWSMLLFWIPVCIGIVAFCYFVKHSRTNKLLMLSFLPIVFFI
                     VQIVKYTYIESQEIFIFYVVGLFISVVFFIMILSYFYKK"
     gene            complement(20151..20438)
                     /locus_tag="ACIZD4_001422"
     CDS             complement(20151..20438)
                     /locus_tag="ACIZD4_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990364.1"
                     /translation="MKLKDGFYSSSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFCGYVEHLYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVI"
     gene            complement(20435..20638)
                     /locus_tag="ACIZD4_001423"
     CDS             complement(20435..20638)
                     /locus_tag="ACIZD4_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HGC5990365.1"
                     /translation="MNNRHRRITKLRKRELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASGAIRKFGISILSDDRKWEEKE"
     gene            complement(20568..20837)
                     /locus_tag="ACIZD4_001424"
     CDS             complement(20568..20837)
                     /locus_tag="ACIZD4_001424"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990366.1"
                     /translation="MSDPYITKLEKLSEDFEKNKNKLTKDKLIELVRLVIRGAITREK
                     AQQNIEIFARSVRDGLEKKVKQNEQQTPQNNKTKKTGTECTKDKV"
     gene            complement(20834..21364)
                     /locus_tag="ACIZD4_001425"
     CDS             complement(20834..21364)
                     /locus_tag="ACIZD4_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HGC5990367.1"
                     /translation="MNKKVLIDKQALIDELMKIPGVGSNSDALETIKRFPSYEPQKPV
                     VPKFVAELLDYYRQSTDVDLLALLITFHDWYYRKTKDGEHEEAIDWLVDHPEIYMRAW
                     LFGYELEKEPLYCVIINGRYLVKVFSNTNVVILVPADEFSQYVTQKFQLTEKQIKAID
                     ERYWPFAVPVDEVVEG"
     gene            complement(21357..21671)
                     /locus_tag="ACIZD4_001426"
     CDS             complement(21357..21671)
                     /locus_tag="ACIZD4_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HGC5990368.1"
                     /translation="MEELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EYGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     DE"
     gene            complement(21671..21970)
                     /locus_tag="ACIZD4_001427"
     CDS             complement(21671..21970)
                     /locus_tag="ACIZD4_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990369.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWSEKTKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKRENVDSKGRQFKHWEKK"
     gene            complement(21973..22134)
                     /locus_tag="ACIZD4_001428"
     CDS             complement(21973..22134)
                     /locus_tag="ACIZD4_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HGC5990370.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            complement(22131..22448)
                     /locus_tag="ACIZD4_001429"
     CDS             complement(22131..22448)
                     /locus_tag="ACIZD4_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HGC5990371.1"
                     /translation="MKSEHQIQDEIRIALSKHGCTIFRSNAGQVTTIEGRQFYGMPKG
                     FPDLCGHRNSDGKAIYIEVKNERGKLREDQKRFAEFLNGQPVLYGVARSVEEALKIVE
                     ESS"
     gene            complement(22695..25007)
                     /locus_tag="ACIZD4_001430"
     CDS             complement(22695..25007)
                     /locus_tag="ACIZD4_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage/plasmid primase, P4 family"
                     /protein_id="HGC5990372.1"
                     /translation="MYEKIPKELKNLKQWCVYKLVWDEKRQKHTKIPYNANNGHKAKS
                     NDESTWSDFQTALAAIDHYGMSGLGFFFKPPYFGIDIDNAEGEVERFKSGDIEENIIY
                     EFIESMRSYAEYSQSGTGIHIIARGELPGGRRRKGDVEMYQNGRFFVMTGNAASKYLE
                     ITEPNPKDIKRLYDRYVGDEKIIQFKEENPLMNTVDLPVEEIIKRAESSSQGARFKVF
                     MNGGWEAFYSSQSEADMAFANDLAFWTGRDFEKMDEIFRASAMIRSKYDQKRGSATYG
                     ESLLNKAIADTNSVYNPKRKSDFKIFIKDQEQPKEEKYYSYDDTGNADRFTDIYGTLV
                     KYSYIDKSWYYYDGKVWLQDNTGEVRKMIDTTVDIMGKEPLTIPEGADDETKEALMKA
                     KEKHVKRSRSNAGKNAMMDELKHRLSVLPEEFDKDKTLFNTQSGYLSLHDGLLHEHEI
                     DKMFTRVSNVEYTESVDCPMWEEFINQIFDNDQELIRYIQKCVGYSLTGSTREQCMFI
                     LYGHGSNGKSVFLEIISELMGNYAMTMQAQTIMVKQSQSSANSDIARLKGARLVTSSE
                     PNEGVRLDEGLVKQLTGGDKVTARHLYGKEFEFEPEFKLWLATNHKPIIRGTDDGIWR
                     RLNLIPFTVQIPDHKKDKNLKFKLQTELQGILKWAIDGCLLWQREGLEKPKSVVAASQ
                     DYRNEMDQIGTFIETCCETGPGLKISGGELYKVYREWASDNGEHTFTNTKFGREISKK
                     YSKEKAGGFMVYKGITLKPRKYDNVRELFK"
     gene            complement(25022..25522)
                     /locus_tag="ACIZD4_001431"
     CDS             complement(25022..25522)
                     /locus_tag="ACIZD4_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010050472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HGC5990373.1"
                     /translation="MTGFNLDFSKAQQGNEIKDGTYEVVVNKAVENATKSGAEFIDID
                     LIVRNDVDQPFQNKHIFAKIWKAKATGKYNEGMIMAIAQALQLEDGKSYNGFDELLAD
                     FVLKTASVRVKTEESNGYKNVNVKSWDKTNTRGVMNHQFKNGDEPSFGPERSRATTVR
                     NDNLPF"
     gene            complement(25524..25985)
                     /locus_tag="ACIZD4_001432"
     CDS             complement(25524..25985)
                     /locus_tag="ACIZD4_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HGC5990374.1"
                     /translation="MGGIFGKKAEDVQGSIINGVTIIGDTGKRDSSGNQIVIARNKNN
                     EVFESSLSNIKRGVVNGTGEESGYVNLKKANEKYHVEGTYVKALSVGGTKGVNWDKRR
                     NKWKARLYFKGEYVLQKDFNTKEEAIQARLAAEEKYFKPILEKYENKKEND"
     gene            complement(25988..27337)
                     /locus_tag="ACIZD4_001433"
     CDS             complement(25988..27337)
                     /locus_tag="ACIZD4_001433"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC5990375.1"
                     /translation="MELYDYQNDLVDRARQAYVDGYKAPCIVSPCGSGKSVMVAEIAK
                     RTTRKGNRVLFLVHRRELIDQIKDTFQKMGVDNQLVNFGMVQTVVRHLKTIKKPQLII
                     TDENHHGLAASYRKIYEYYSDVPRLGFTATPIRLNGSGLGDVNDLLIEGVSAKWLIEN
                     HRLAPYEYYAPKLIDTAELKKASTGDFTKKSMDKAVKNTIYGDVLKHYKTLAEGEQAI
                     AYCHSIDASKHTAEIFNDAGYKATHIDAKTPKDERADIIEAFRNHEIKILCNVDLIGE
                     GFDVPDCSTVIMLRPTQSLSLYIQQSMRGMRYRPDKTSIIIDHVGNVNRFGLPDMDRE
                     WSLDTKKKTKTDSDLSIVQCAFCFGAYERPKGDNICPYCGELQPIEERKSELEIDESA
                     ELMKVGETKITLNFENNKYYNMTEDEAESIEDLYAIARAKGFKPGWAYMAAKRKGWL"
     gene            complement(27312..27998)
                     /locus_tag="ACIZD4_001434"
     CDS             complement(27312..27998)
                     /locus_tag="ACIZD4_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5990376.1"
                     /translation="MQIKKATDIEQTKGTYLIYGAPGKGKTSTAKYFPGKTLILDIDR
                     TSKVLRGEKNVDIVYIDNEDTWNDWGNTLADLTTNYVGVYDNVVVDNVSELERCILSS
                     LGAEGKNNGVPSQGDYQYMQFRMVNSLRYMKNLDSNLIWTAWEEIDLWTDSDGSSYNI
                     ALPQINRKIRNNILGLCDVVGRLMVKEDDERGFILQATDSTYAKNQLDNRSGCKQSEL
                     ILDGIVRLPE"
     gene            complement(28117..28434)
                     /locus_tag="ACIZD4_001435"
     CDS             complement(28117..28434)
                     /locus_tag="ACIZD4_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HGC5990377.1"
                     /translation="MTIYDPNISWAKHTIKVSFMIWGYKGYVTYKVGGNTKGLSLIAI
                     DSDDLYDANFEDNPVNFRDLDEDWFSMELTNDKGDSTLVEDEFDRLGDYIVGVEIIAH
                     EPE"
     gene            complement(28440..28871)
                     /locus_tag="ACIZD4_001436"
     CDS             complement(28440..28871)
                     /locus_tag="ACIZD4_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990378.1"
                     /translation="MKNKLAKTTAIIGLALGSGVIGYAASNAFQDLDTIKANFNTVLQ
                     YGQTKSQRVSELESQLSNNTRTQEQLKAEIEQIKSDKQKEIEAKQREVEQKQQEIATK
                     QQEADSLRQQLSTVQNDKEQLEQRVSELRQYTDQKVGELGK"
     gene            complement(29128..29304)
                     /locus_tag="ACIZD4_001437"
     CDS             complement(29128..29304)
                     /locus_tag="ACIZD4_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990379.1"
                     /translation="MEHENVKDALKAAIEIAEAKGIKVDGKPATVHDIQNLTKEHLYF
                     IADLLGLSELYLDK"
     gene            complement(29321..29800)
                     /locus_tag="ACIZD4_001438"
     CDS             complement(29321..29800)
                     /locus_tag="ACIZD4_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HGC5990380.1"
                     /translation="MATLYQLSESYIKVLELAEQLDEEILRDTLDSINEAIEYKAENL
                     AKIVKEVEGKAELIDSEIKRLQERKTSLLNNAKSIKHYLQEEMEKTGKTKIKGELFNI
                     GIQNNPVSVNVINENLIPKGFFTPVPPKLDKKQLKEELKHGDIPGAELVQTKGLRIR"
     gene            complement(29733..30050)
                     /locus_tag="ACIZD4_001439"
     CDS             complement(29733..30050)
                     /locus_tag="ACIZD4_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990381.1"
                     /translation="MLIATDTLDRIFLKDEYKLRNIDASGILVFDLYDNGKIGIYQAS
                     DIEETNLAFEQIDDSVELDLDEAILAFEQIAKLLKEAQKNGNSLPTQRVIYQSPGTGR
                     TIG"
     gene            30209..30676
                     /locus_tag="ACIZD4_001440"
     CDS             30209..30676
                     /locus_tag="ACIZD4_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990382.1"
                     /translation="MNYLIKILSDYQVAITLIISISGFFLSLYNLFKDKRKITLSYFL
                     VKHDRSNRMILTGVIANPSKMPNSIIECTYLYNGKKINCSHYHANGFDMGSIHKSSLL
                     SPIPLAQAISPGYSVAFSEVLDMKDILPGEKLVMVIRTANYQKKFKLKLKDSF"
     gene            complement(30778..30948)
                     /locus_tag="ACIZD4_001441"
     CDS             complement(30778..30948)
                     /locus_tag="ACIZD4_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990383.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFIGLDE
                     AEYKTKKPVGRD"
     gene            complement(30979..31227)
                     /locus_tag="ACIZD4_001442"
     CDS             complement(30979..31227)
                     /locus_tag="ACIZD4_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990384.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
     gene            complement(31240..31425)
                     /locus_tag="ACIZD4_001443"
     CDS             complement(31240..31425)
                     /locus_tag="ACIZD4_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990385.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALIGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            31729..32103
                     /locus_tag="ACIZD4_001444"
     CDS             31729..32103
                     /locus_tag="ACIZD4_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5990386.1"
                     /translation="MSLVTKIKELADEKHVTIAEVERQVGISNGQIRRWDKASPKSEN
                     LKKVADYFGVTTDYLLGNNNVPKWATKEEVVELDKLLDSNVNMSYGGETLTPEQIQRV
                     KDILIATFWDIVKEDKEKGKKM"
     gene            32108..32536
                     /locus_tag="ACIZD4_001445"
     CDS             32108..32536
                     /locus_tag="ACIZD4_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGC5990387.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRDRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIEELKNLYGLPESAYRFLI"
     gene            32586..33239
                     /locus_tag="ACIZD4_001446"
     CDS             32586..33239
                     /locus_tag="ACIZD4_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990388.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDTTSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            33375..33941
                     /locus_tag="ACIZD4_001447"
     CDS             33375..33941
                     /locus_tag="ACIZD4_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGC5990389.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWLLAVVVVFIAIGSQGGSD
                     DAKNTVAETTKESVTEVSSAESVAESTVVEEETETTETTIEEVTQEESVPREYRNALS
                     KAESYLGWAGMSEQGLREQLEFEEYPSDAIDYALANVDVDYNEQALAKAESYDDWASM
                     SDSQLYDQLIFEGFTNEQAQYALDNLPQ"
     gene            34057..35193
                     /locus_tag="ACIZD4_001448"
     CDS             34057..35193
                     /locus_tag="ACIZD4_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5990390.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLHKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKIPETYIVSGINTIDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PIDEVVIDYKRESKTIKIKDKFLEDDEYNRLVDFTTSHNKRYSLLFQWLYLTGMRSGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPNGQFLFQTTKGTPFQLTAINTYLRSHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(35325..35672)
                     /gene="rplS"
                     /locus_tag="ACIZD4_001449"
     CDS             complement(35325..35672)
                     /gene="rplS"
                     /locus_tag="ACIZD4_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGC5990391.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(35808..36569)
                     /gene="trmD"
                     /locus_tag="ACIZD4_001450"
     CDS             complement(35808..36569)
                     /gene="trmD"
                     /locus_tag="ACIZD4_001450"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGC5990392.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            complement(36559..37080)
                     /gene="rimM"
                     /locus_tag="ACIZD4_001451"
     CDS             complement(36559..37080)
                     /gene="rimM"
                     /locus_tag="ACIZD4_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGC5990393.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            complement(37250..38041)
                     /locus_tag="ACIZD4_001452"
     CDS             complement(37250..38041)
                     /locus_tag="ACIZD4_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990394.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
BASE COUNT        10415 a         8217 c         6444 g        13088 t
ORIGIN      
        1 ggtaaccagt tagctatacc tcttcgttta taatataact ctactccacc ttccacttca
       61 gctgatatct tattatattt aaacgagttt tcacccttag aaagtgttcc agctgaagta
      121 ttttgatttt caattaagtc gtatgatagc ttacttaaca aattcggatt ccccgaataa
      181 tcatagcccc caaagtcgat gctgttactg tacatctttt tcagcttgcc gagatcgccg
      241 atttgctgat tggtttgatc aatacgatca tttacttgct tatctgattc atttatcaat
      301 cttactaatt cgttatattt cgagtagatt tgatcgtatt ggacctgttt atcactaatg
      361 aactgattga aagtggtttg catttcactc tgtaattttt ccaatgaaga aatatagtat
      421 ttcgcttgct ccgaattaat atccactcgt tctaacacgt ctatgatgaa gttctgaaaa
      481 gttacttttt tgccgttagg atctacatat tcaaaatatg cttgtttgaa ttgatgactc
      541 gtgctgaaat ttgacttagt gaacgtgtaa ctaattaacc cattagtcga atcgattatt
      601 tctggttctc cctcggtata gttaccgttt gaaacttcgc ccacaaattt caaagtaccg
      661 tttagattaa ttacaaaagg tgtaatttca tcttcctcaa gaagttgtac attgattgtt
      721 gtgagccccc catcaccaac tctaccaaca acacggtgac gtagataagg ctgtctctta
      781 tttgcagata atttaatttc taaatttgcc actcttccat acctcctaac taaaaagaaa
      841 ctatatacct aagcaccata tttgcgttat ctccacttgc attgcttgct gcacctgtaa
      901 atatattagt attcgaatta tagtttattc gtttactaaa ccactttttg tgatagtcat
      961 caaatcctga aacaatttct cctaaaacat tagtaaaagt tacacgctcc ttataaaaag
     1021 gcgtagttac atatctatcc tcaattgctt gcccgttttc gtatgggagc catactaaca
     1081 aaaaacctga aactgtctgc caaatttttt ttgaaggttg gacagtttga gtatcatgca
     1141 ttaacgcagt ccccctccac aaaatttctc ctttagagag agtcagctcg taactatccg
     1201 atatctttga gattgaaaca gttgatccag tagaattaac tgagcatagt ggtaaattat
     1261 agaccttatc accattgttt aaattacctt ttataacttt tgttataaat tctagcttga
     1321 cttgattatt agtccattca tattcttccg attctggaag aatagatcca ggtataactt
     1381 cttgtgtcaa atccactgtt aatgctatat aaccacttga gtttgctgga actgttatac
     1441 tttcttcttg tcgaacaacg accatacgac cttgaataat cgctgctcct gcagcaactt
     1501 ttactgttaa tccgcttgaa gataaattca tagactgatc gtaaccatca ataacctgat
     1561 ttttccgatt atataaaacg tgataaagtc tagcatcatt ttctgcgctt actttcacgt
     1621 tttcaaattg atatccatcc acattgctaa ccatttttta tcccccatta tcttcaaaat
     1681 aatccataaa acgacttctt atgtttccga aagtcaattc cacaaactcc ttatcacttg
     1741 atattcgcca agctgtcaaa accgacttgt atatctttcc tttataagaa atcgtggcaa
     1801 acatccctgt ttcaatcgtt tcgacattca aattttttgc atttcttaca acgttcactt
     1861 tgatttcatg cgaatacgta ttgcctttca actctgattt tgccacatct tcgtaggatg
     1921 ctttatcttc tgcggtttga tcgtagatat taaccaaatt gacagttggt ttcgtgatat
     1981 tttctttcga tccatcttgt gtcaaattgt tttcttcgtc caaataccat gttgacagta
     2041 ttatcggttt ctctatatct ttcattgctt tatcaacgat taatagcttg ttctcgtttc
     2101 cagcgcccgg cgcctgaaca aacacatccc aatcgctaaa ttcagaagaa ttgtctttaa
     2161 tgtaaattga ttcatttaca gcacgtatgc ctgtataaat ttttctgttt tgaattccct
     2221 tgaaatacca ttttacgttg tattttttga aaccattgag aatatacgca cttaacttgt
     2281 gtttattcgt atcggtagct tgatacgaat gagaggtcgc actttctgct ttgacgtcta
     2341 aaatatcttt tagttgtttc gttggatcat tcagcaaata gtattcaatc aaccgccgga
     2401 tatgctcttc gtagttatct cctgacacac gtgcagtcgg tatctcacta tcagctaaac
     2461 taagtaagct tttacaactg attttttcgt cttcctgcga cgtaattaca ccaaaatatg
     2521 caaattttcc actaggaata tattttgcta gtagaaaatc gcctgttttt acaggaacgt
     2581 acttatccat cgtaaagcta ctagcctctt cgttgatctc gtccacacca aattcaaaac
     2641 tgttagagaa taaatgttcg ttataaagca ttaaatcacg atgaaaaagc gtgactgcta
     2701 aaatcaaaac agatcacgct cctcgtataa ctcaatctct acgtctgccc ccccaacatg
     2761 aaacacaatg ctgaattctc cagttggggc ctgaacaaaa ttagtttttg tataatcctg
     2821 ttgttggtag acagaagatt ctacccctgc aatatctttt aaaatcgccg ttgtatcttc
     2881 aaaaaggctt gatacttcta gagtctgtgt ttcagtcata tctatgaagt atccatccgt
     2941 tgcgatgatt tgtgagtttt ggattacttc ccaatacgga tttgaacact tcccaatcac
     3001 acgaattttt agcggggaca tccgttcctt gctattcgtt aggtatacag aattattatt
     3061 gaatttgaat acaccttttt tctcccacaa gttttgagtg tagatataag atcttttata
     3121 cggaaaaacc ttaccacgtg ttttcactac attcggtcgc tgaattaatt tttcgcgttt
     3181 tacggaatac cagtttgatg tgaaatatag ttctaaagtg tctgttagta acgatgtttt
     3241 cggatcgatt tcagtcttac ttaaagattt tagactgcat cttcttacca ttgtttcgcc
     3301 gtcaaaagca aattccagtt caaacggacc ttccgatagg aactgcacaa gtgaattgta
     3361 cagttctttt tctcgaaacc catgcacaga aatgattaca gatgactgaa attcagatat
     3421 ttcaacgctc tcactgcttt ctctgaaatt cccccactgt cccacatgtt ctttttttac
     3481 ttcaaacccc atattactca acccagtagc aaaatagtct tctgtggaca aatcaatttc
     3541 ttcgtttatt ctatttctca gtaatacagt tcgcatctac atcctcctaa ccaagatctt
     3601 ctgaatatct aaagctaaat ctctatcagt tcggctattt cctttgaaaa atgccagcaa
     3661 taacgataac agctgattcg ttgttgccgc ctgtttttca atggcttcta ggatttcgta
     3721 atcactggaa acagttgtcg catttccata agttttagga gaaactccta gtttgtccat
     3781 tgcgatagac aataattgca tcgctcttga tcgtttagcc ttatctaacg gaataataat
     3841 ttctggcttg tttccttctg cgatttccgc aatttgatgt tggtttacaa ttccaccgtt
     3901 tgcgtaacca actccacgat aggcatttgt tagtgagcca tatcttgata gtgcgtatct
     3961 gattgaagct aagatgttag atagtgggtc aaaaatattg ctgttgaatc ctggcattgc
     4021 atactgtctg aatgttgggt caatcacttg gagcaaccct tttgatggtg ttccattttt
     4081 ggcgttaata tcccaattgt taactgcatt aggattacca tttgactctg tacgcatttg
     4141 atttagtaat gcatttaagt ttgcagtact gtattgaccg gtcattttca acgctctaat
     4201 tgctacattg cgccatcttt ctaccccact gcctcccacg ctatctcctg aaatttgagt
     4261 gttttgtggg tctttcacac cgtttaaatg cacatgatca tagtgatctc catcgggcca
     4321 tggctcccat gcaccagttg ctggttgacc tgattgtcct gaacggtcac gaactttccc
     4381 attagtgatt acgtaaccaa ttttggaagc gaatttgtca aaagcgtagt ttgctgcttc
     4441 tgtgtatcta ggtgagcctc ctgtgacgcc tggtaatgca atatcaatgg cattacgttt
     4501 accatgtgaa taagggtcac ctggtctata cccactagtt gccacaaatc ctgggaattt
     4561 cttcatcaca gacttagcaa catcagccaa atatttatag acgccatttg ttcctacgga
     4621 ggtatctaag ttaccagatg agaacaaccc agtgattttt tcagtcagtg cacttgttgc
     4681 tttagatagg atgcctttac ctacttctaa tggatacttt gtcaatccac ctaatacatc
     4741 taacccccca agtacttttc tagctaacgc tcccgggtct gaaataaagt cccacacgtc
     4801 acctactacg tttttaattg tgtgacctac attaccagca acctttttca cactatccca
     4861 catgttacca aagaagttag tacctttttt gtaacgatac ttaggagctt tagaaccttg
     4921 aagttgcgcg gtctcttctg ctgtcaagac atgcgttcct tttggtgcgt ttagaacaac
     4981 attgcgtcct ttaggaatga aggctctacc atctggtgtg ataactgttt ctgctccacg
     5041 tccatcatta accatcattg gaccattgat tgggtgccca cctgctggtg tacctgtagc
     5101 gtattgtggt acatcccatt cttgtagagg ttctgcgccc aatttttcta gtacccatga
     5161 agctccatgg atgattgcgt taactggttt acctatcgct ttaagtgctg cgttgaaaat
     5221 acttttgaac gcatcaacaa tggcgttttt accgccaata atggcattct tcatcttcgt
     5281 tggtagttct gaaaaccaat tgaataccgt atcgatacct ctacggaatg tgtctttgat
     5341 accattccac aggttaccga ttacatcaga aacgttgttc ttcaattcag ttgctttgtt
     5401 gaaaatgttt tttacccaac cgactacctt attccacgta tctccaacgc cattgctgaa
     5461 gaagtttttc acgccattcc ataggttctg aaccgtattc acaacgctgt tcttcatttc
     5521 aatgaattta ttgccaatcc atgaagccca ttcttttatt ttttcccaaa gccactgcaa
     5581 cacgctccac aacattttgt agtattccac caaattattg ataacgctca taactacgtt
     5641 tttcacagct gtaaaagccg cattgactat atttctaaat gtttcagatt ttgtataagc
     5701 tatcaccaaa gcacctgcta gtgcgcctaa tgctacacca atcgccacaa aaggggctgc
     5761 caatgttccg ccagtaattg ccagcaacat acttgctacg ttcaatgctt ttactgctaa
     5821 tgtaattccg cctatgattc cgacaatcca tgttagtggc tctctatttt caacgatcca
     5881 cgttccaata tctctcaacc aacctataaa ttgagtaatt ttaggaatag aattttcaat
     5941 cccttttgtt actctgttga tgaaaccagt gatattttca acgcctattt tttctataat
     6001 actttgtagc ccatttatta cagtggattt catctgctcc caagaaccgc tcaatgtgtc
     6061 tgtagaagtg gctgccttaa ctgctccgtc attcatacct aactgtacaa ttgcttggtt
     6121 gaactcgtcg gaagtgattt gaccttgcgc cattgcatca cggaagtttc ctgtataagc
     6181 tccgtttttc aacatagcgt cttgtaacaa tcctgaagca cccggtatcg catctgctaa
     6241 ttgattccag ttttcagttg ttagtttccc agctcctgcc gtctgcgtta gcatcatggc
     6301 aacggatttg aatgtatcac tagaaccgcc tgcaacggca ttcaagttac ctgccgcctt
     6361 ggttagttct gtatagttag gaatcccatt agatgccaat tgtgcggttg tgttcagaat
     6421 ttcttctaaa ccataaaccg tcttatcggc gtagtctttc atttcttttt tcgagctttc
     6481 tatctgtgac ttcccaaagt tagcaaactc catggttttg gaaaacttca tcaatgaatc
     6541 cgatgcgttt actgcttcgc caaccaaacc ttgcacgcca cttactacac tgctaatagc
     6601 gttatgcgct aatccagcaa ctgcaccaaa cgaaaatgcg ctttttagcg agcttaattt
     6661 gtcttttagt ccgtccagtt tcctagctga ccttgtggac ttgtcgccaa aatcttctat
     6721 ttcttttcct gattgatcgc tggagctttt gagtgcttct aattgcctgc tagatatttg
     6781 gctttgtcgt tctaactttt ctaatgccct ttttgcatct tcggtttcat ttgctgaatc
     6841 gccaaactca tcagccatca gtttcacaac tttgcgctgt tcttcgatag ctttctcgga
     6901 taattccgtt tgtttggcta gccctttttg ttttgcttca aaagcaccag attcatcacc
     6961 agcggctttc aacgctttta cttcggcgtt catttgtcgt tcattttctt tgatttcatt
     7021 agataaatca ttgacggctg ttttggaata caccaattct ttttttgtgt cgttcaactg
     7081 gcgactgtaa gcattatatt ttgcggtagc attgtttatc tgtgtgttaa ggttagcaac
     7141 ttgtttcgat tcctcgccat acttgctaat cgcttcatca cggcgctttg ttaattctct
     7201 tactttggcg ttttgccctt ccataaccgt agacaagtct ttcgtctttt gactaagtgc
     7261 ttcgtatgaa cgtcctgctg aatcataagc ctttagattg gcacgcatat tcgactcagc
     7321 ttgtttgact ttcgcattga tttcgtccag cgtgttacca aaactagtgc tatctaaact
     7381 aatccctagc ttgatatttc ctgccggttg tccttttcct gccattattt acctccttcc
     7441 tcaagtttta ctaagtcttc agccgataaa aattgtttga tgaaatcagc accatctaca
     7501 tattcttcgc cactctccac ttctccaaaa aggtgtaaca aataatgata gtcggcttcg
     7561 tccacatctc tcatcgtcca acctgcttcg attaaatctt tgtagatttg atccattgct
     7621 ttcctagctt cagaaaaact tatttctttt tgctcgccgt ctgctttttt tcattgtttc
     7681 ccagttcatt tatttgttca aaaacacttt ctaatgccgg tactaactcg ctcgcagtca
     7741 aaccgtctaa aatagcatca aatgtaactg ctggatcttg gaaaatatct gctgtaattg
     7801 caatcattga atcaatcgct tctaaatcag ttaggtctgc tttttccgct ttctcgtaaa
     7861 atttgataca ctcacgcatt gcacgtgcgg aaatatcttg ttgtttgaat gtttttttct
     7921 ttccgtcaag tttcaattgc aattcaatca tttgttttcc tccttgtttt tacaaaaaat
     7981 aaggctagcc aaaaatggct aaccttgtgt atcaattttt ggttctggtt cttttggtgt
     8041 ccctgtatct gtcgttggtg tagatgcagg gttaactact ccccctcttt gttatttacc
     8101 aagtccttga atttttgtaa ggtcattcct tctgattcta cggctgttaa gtatacatag
     8161 ccacgttcat cagaaatgaa ttccccttcg atggaatcgg tttgcaattc tacccctttg
     8221 tcttcagctg ttttcatgtc gatatctgga tgactgaatt ttccttttgt caatcccatg
     8281 aacaagcgtt ttccttcttt gttcgctgta accatgacta ccgacacgta aggcgcttca
     8341 gtttctgaac caattacatt tgcaccatcc acggttttag caccaatgat ttcgctgtaa
     8401 atgccgttat ccattaagtc tgccacgtca agcgtaactt ttggcgacga aaccccttta
     8461 cttgcaatga agaacggtac gtttgaagcg tatgttgtgt tagaagttgc gcctaatcca
     8521 gtaattttag cttcgatcgc tccgcctttc gacttatctg ctactaattc ttttagagtg
     8581 ccgcctgcac ctgtttttac gccaaaaatg acgctctcga atcctactgt tgccatctat
     8641 tttctctcct tttaatttag tgaaatattt gctacatatc gtttgataat ccgctttgca
     8701 ccttccaagt cctcgtcatc tgtttgttcc gtgtatgcgc attgccaacc attccccctc
     8761 ataacctcat caagggcaaa ataaaaggca tcaacctctt tcatggttga cacccataca
     8821 tctacctgta cgttaaattg aatggtcaaa ggattgttgc ttgcaaaatc ttcatagttg
     8881 ccggatatct ctgtaattct gccaactgga aggctaggta ctgtttgagc tgattccgga
     8941 acactattgg tgtaaaaatc aatgttcttt gttttttcat tgctattcag aattgaatag
     9001 acttgtgata ctgccgtttt caaagtccta gcctcctttt tacttcgtca gcaatgattt
     9061 gtgttacttg tttttcgatt tgcttttgtg ttttttgtac gaaacctttt ggacgttgtt
     9121 tgattgttcc gaactcgata aagtgcatcc gccaagaaac atctttgtca tagccgactt
     9181 ctaccaatcc gttttttatc gagcttgtaa ccacatggtt cttagcatgt tcttgcatat
     9241 acgaaccacg tttaccgttt gacttcgttc catcccagta aggtgtgttt tgtcgtaact
     9301 cttcttgagc gtactcccca gcttttctaa gtgctgggct ttccactcgt tgaacgtttg
     9361 cttttacttc cctaagcgct ttgtacactt cggttgcatc gacttctaca ctcattttga
     9421 aacctctttt gcaatgattg tcgtgaagtc cttcgcaaac tcgcctttcg taatcgtaat
     9481 gatttcaaac gtttttccat tccaacgcac tttcatatca ttggtcagct ctgatttttg
     9541 ttggtagcgg ataatgaacg tcagtgttcc ttccaaagcc gtaccaatcg acgtcttaat
     9601 atcgttcagg cgttgtgtct gcacacttgc ccagcaagta agaatggttg tagaagtcgg
     9661 gacaacttgc ccgtcctcat ccttaaccgt cgtatctcgg acaaacttga tgcgttgatt
     9721 taaatttcct gtttggataa ggggcatacg ctactcctcc tccacaaaaa gcaaataact
     9781 tgctttgagt tgcaagatta ggcttgtaaa acctaaatcg tactctcgca agttcccact
     9841 cacggttgct gatcgagcgt tgtaataatg atctgctaat tgcaggatag ctaaattaat
     9901 cagatcaacc gtttcatttt cttgcttata aaaagagggc ttatcattcc cgatagcccc
     9961 tctaatgtat gcaattgcag cttgtgccgc acggcttact tccacatcgt catcatcggt
    10021 atcaatcttt agtgcgtttt tgatttcgcc taaatccatt ttaggatcaa gaatcataag
    10081 gaatcagctc cttaaacttt cgccggtgtc tcgttcgcaa tagttgtaaa agtagccaaa
    10141 acaaccgctt catcatcaac tagttgcaca tcgaagcgat cgatgacgcg tactttagtg
    10201 gtgtctgttt caaaagctcc accaccaata ttcgttgtca gcaagctcat gttttcgcga
    10261 tcatacaatg taacggcttc tttcagatca ccaatgtaca gtggatattt aggagtagct
    10321 tgcgtacctt tgtttggcaa gaaacgagaa gcaattttct tgattggttt acctaagaag
    10381 gtatatccag ttgcagaagc tacgtctttt tgtaacaagt aagatccatc agcacgtttc
    10441 actttatcta aaacattgaa gccatcttgg tttgtaataa acatagatgt agcttcgata
    10501 gctggatcaa gttggacgtt tacgatatct ttaattccat caacatctgt aacatctttc
    10561 ttttgtgccg ctttgattcc atcaatagct gccaagattt ttgtattgcg agtaacaact
    10621 acttttttcg cgatccattt agacaaccat gccaaaatgt tttcggcagt atcttttagc
    10681 aagctgttag ttactgtgga aatacctgca tagcgtttga tcaagtattt gatcaagtaa
    10741 agtgcaggat catcatttgc tgggatttca ccgtcttcag tatccaaagc agtcaacggt
    10801 gtaatatcag accatttttc ataaacgcga gaaccgctgg tagtggtcac tttttcaacg
    10861 tttacgtatt cttgcaaaga gtcaaaccga cgaaccaaag tatgaatagt cgtttgcaca
    10921 tctacaggaa tagtcaatcc gatagcatta ccagattcat ccgtattaga tgtcaaagta
    10981 gccataatag caggatcacc attgaccatc gctttaaagt ctttgataaa cttgtttttc
    11041 aagttttcat cttttttatc taatggttct tttttgacgt ttaagacttg ttcggcttcc
    11101 atatttgcca cttgctcttt caatccgtcc cgtttagccc gtgctgcttt tacttgtgct
    11161 tgcaaactta ctacatcttc ttctgttttt tcatcgtcaa ccaatgctgc attgagttgt
    11221 gcatttaagt cagagacttt acttcccgcc tcgacccacg cattttttaa ttgttctaaa
    11281 ttcattcgtt tttccctcca tttaaggctt ttagtttttt ctgtaagagt gtttcttctt
    11341 gcggtgcttc cgctttgagt attaaatttt tcaacttagt tactgcgttt tttggaataa
    11401 ccggttgaga ggcattgagt accgttactg gtgcttctgc aaacataatt tcatctgcaa
    11461 acccttctgc tactgctgtt tgagcattta accaagtatc tttcgccatt aaatcagcaa
    11521 gttttttccg atcgagtcct gttttgatct cgtaagcatt aacaatagac tcatccacac
    11581 tgcttaacat ttctgcattg gcttttaatt cctcagcgtt gccactagtg gtcacccatg
    11641 cgttatgaat catgatgtgt gccgtaggtg agattctaag cggttcgcaa gcgcaagcga
    11701 ttacacttgc agcgcttgct gcaatactca caacatttcc ggataccttt cccggatagg
    11761 cacggatagc ggtatatatt tcgcttgccg ctaggacatc cccaccgttc gatgagatat
    11821 caagttctac ttcatccccc gctgcttctg taagagcggc agaaattttc cctggtgaga
    11881 tacaattgat cccaaaccag tcataaagcc acgcggtatc gttatccacg acatcgccgc
    11941 ttaacgtcac ttttttcatt tttccacctc ccttcggtgc aaactaaaaa aacctaaccg
    12001 ttttcggcta cgcttttaga cgaggttgtt tttcttaatg ttggatccat atcgattgga
    12061 tataggtctc cggaaatatg gtaatcatcc ataccggttt tatttatcgg ttgcaagtcc
    12121 tcaaatcttc ggacatcatt cgctgagtat gctccgcctc gtcgcatgat ttgatagaat
    12181 tgtccccttg cctgagtgtc agctcttagc aaacttgcga cattaaactt atatcgataa
    12241 ccttttgctt tttcggttct cgatagtgtt ttcttattta gttccgcttc atattgatta
    12301 acggtcggta ctagattgta cgtcaaaaat tccatattga gctgttcctg agaggagtaa
    12361 ctcgactggt tattcccgat gaaatgctcc ggcacattgt agaccatagc gattctggag
    12421 cgagatactt tatcagtatc taaaagcttg ctgtctacca gctctcgttg taaacgttcg
    12481 atttctacac cgttttcttc cacaagtagt ccaccgtttt gtcgataaaa atcagcaatg
    12541 tttttaactg tagctttttt agcttcttca tccatattgc tagcaaactt aacttttagc
    12601 ccttcattac ttcctttaag ctgacttaaa gagatttttc ggacttctcg atcatatccg
    12661 agggtattcg ttaatacttt tgtggggtct gtaccttcca agccgccaaa cctcggttgt
    12721 ttaaagtgaa gcatttccat gtaatgtaca tagataactt gcttgtaact gcctttgtca
    12781 gtcgcagtta cttggtagta aagctccccg ctatccatat caatcactgg atggcaagca
    12841 ccaggtttta ctaacgccat atctgctact tctccattga tatttcggaa aatctgcaca
    12901 tacgcattcc cttggtagtt tctcaaaact tccacgtccc ggaaaaaatc aaactttgta
    12961 aaatatcgag ggccttcgct caacaagttg tatgcaggac agtcgtccgg ttggccaaac
    13021 tccacatcta tcattttgag agggagagac gcaaaaacgt tcgatacacg gctaattacg
    13081 gaaaaaatcc cttctgatat ttcatctttt ccgactaaat acggtatcaa tcccgggtca
    13141 ttcaaaaaat actcttgttt gctcgctttc ggcttcgctc ggccaaaaga acgcaaacga
    13201 tctaaaatac tcattcctcc acacctttct tacatattca ttaaatcgga aatcgagtaa
    13261 taggttactt tcccggttcc gacaggatta accaacatat tcaacacttc ggcgtggctg
    13321 ttcaaacttg ctgcaaaacc atctattttt ctactcttgg actgcttaga cggcatccag
    13381 tttgagttgc gatccatcac cagcttgacg ttggatagat accatcggta aagcttggaa
    13441 ttgttgaaaa tcaccttacc gtccaatagc atttccttga agttttgcat tggcccacct
    13501 aatgatagaa acccttgccg aatctcgttg gtttcaaatc ctgcattttc tagttcttta
    13561 tttaatcgta gcgccttggc cttgtcataa ttgattttta caatgtcata gattttcgaa
    13621 ttttctacaa accaatttaa gacgtattca taattgacgt aatcaccagg aataatcgtt
    13681 agatctccca ccttctccca cgctttgata cgctcttgat tgttatctcg atcaaatcta
    13741 gcttgtggga tccatgtgtg ttgcaaaatg aatacctcgc ctgtttcaag cggaaattct
    13801 aaaacggctg cggtaaagtc ttccgtttcg gacaagtcaa aaccaccgac acacttctta
    13861 cctttgagcg tttcaatatc gatggtttta ttgtttcgtt taatggtagg catatcgaca
    13921 aatgacagct catcgatatc ggaaaacaag ttaaattgct tggtaatcca gtcagcatat
    13981 tcttttggat cttttttatc cttaacatag tcatctagca tgccaacaaa attcattaga
    14041 caaatattcg gattggcttt gatccataat cttgggtcat cagcctcttc cgcactgtca
    14101 agttttgcca gataatagaa agtccgttca tcgatgtcat cttccaaatg ttccaaacag
    14161 tccacacctt gctcaaaata agacatcaac ggaccatcta atacatatcc agcagttgtg
    14221 atataaacta tcagaggctg ttttctggtt cctcttgatt tcttgataac gttgatcaga
    14281 ttgtaattcg taaactcgtg gatctcgtca aaaataccaa agtgagtgtt tagcccatcc
    14341 aatttccggc tatctgaggc gcgtggttcc attttagaaa aggcgggagc ataattaata
    14401 cttgatcgtt taggcttacc aaatttctta aagagcgccg gcgattgttt gaccatttct
    14461 gcggccttat caaacaacaa gcttgcttga tcacgagcat ttgccaatac gtaaacgttg
    14521 gcgccttgtt catcatcata agcgaccatg tatgtggaaa ggcctgaaat tagtgatgtt
    14581 ttcgattgtt attatctgcg agctttttat ctcgcactct ggaggtcacc ctcattttca
    14641 tcggtcagtc agttctggcc cagtttagcg tacattttca gcaaattatc tgctgtcgga
    14701 cactcttggg agcattatat ttattcaact cctacgcgtt acggtagtta gtaacctttc
    14761 gcaatctact aacttacctc ggtatcttct ttatgtttga acataattcc ttcgatagct
    14821 aatatttttt ctttatttct gtagttcgct ttaggattta tcacataagg ggcgccatct
    14881 tttaaaagtc ggtaaaaaac acatgtacta atcgaatagt aagccatgca aagcttagcg
    14941 ctgtgaaatt ctcttttagt tccatcccgt tcaattgcga caattggttt tgaggttaca
    15001 gcattttcac cactatatgc tttctttttc ataattgatt ctttgctgtg gtgctttccc
    15061 aacatgcctt ttgggtgttc gtgagtaaca ccccatacaa catcaccgtt tgtcatacaa
    15121 ttattcttat ggttctttgc ccatttactg tgatttgaag aaaattcttt agattgtttt
    15181 ttccctagca ttcctttggg gtgaacttta tatattattc cgccatttcc gccttttgcg
    15241 atgttataac cttttttctt attagttgag tcataaagtt caatataaaa cttttctttc
    15301 tcaaaagctt ctttcatcgt taagtcttct tcaataatca aatgatcaaa attttcccac
    15361 ccgtattttt gtattgcatt ccaaaaactt ctgtggtgtt gggtttcgtt ctttggtggt
    15421 ttatattcaa tcccaccgct cctccacctt ctgccaatat catttgtgac accgatataa
    15481 attttgccat ttattttatt taagtgtttg taaataatgt attttttcaa tctactcacc
    15541 tcttttatat actaccatca attgatggta gttgcaagcg gtggaatcgg atgttatagt
    15601 aaaataaaaa ggagtgtcac acatggacaa atacggacta aaaaacagaa ttagaatttc
    15661 taacgcaatt gataaagatt tatacgaagg attaaaaaaa atgtcggaag aaactatggt
    15721 tcctatgtct aaattgcttg ataaagctat cgaattatta ctaaaagaaa gccaaaaata
    15781 aaggttttca ccgattttgc ccgattttta aacggcaaaa cttaccgttt ttacgtccaa
    15841 caaaaataag agcctcgcgg aagcgacgct ctcctgtatc acgatgtacc catccgtaca
    15901 tggatccaat tatgaaatgc tgccaaggtt gcaaaacaaa cgaaccaaag tcgccttcag
    15961 ttggtttaca ttttttttcg atatatctaa taggccggtg acctttttct tcgtcaaaga
    16021 tccaaggaaa atcatctgtt ccttggcgct gcaaatcacg catatgccgt ttagcagctt
    16081 gaatattttc tttgctggct ggtatgcttc catcgattaa tcgttccgca taccaagtag
    16141 ttaacaattc cggatatgga cattttaaaa agccacccca agaagcttgc tcctcaagat
    16201 agctttgcca atagtccaca cgttctgtgt aagacatatc caaaatatta gaagtcgtca
    16261 tcgtcatcac caccatcatc agccatctta atagctaact tagctctggc tgctggtgat
    16321 agtcctaaat cagcgccaaa agaacggaga ttccgagacg ctgtatccat ctgccgagag
    16381 agcggattac caattaattc attaggttca ttaaacggct cacctctcgc ctctgcctcc
    16441 tttttcgcaa gcgcatagtt caacttgtac tctcgttgta gttttcgaag ctgtttttct
    16501 aaagaaacgt attgcgaata ccaattggag tatagagcca ttgtatggac gtccggatta
    16561 ctgattaaat ccacagacag caattcatcg gcgataaact caaaggtatc ctttcctagc
    16621 gaatctagcc ataacggcgg tttgattttg tcagtagcca tttttaattt gtcttctgcg
    16681 gccgctcgct tgcggagttc ttcggtattc ttcttatttg ggtttccgtt taataattgt
    16741 aattttgcac tcttcgctgg ttgcggcata atatcacctt ctttcaaaag atagattgaa
    16801 atcgttatca caatccttat aattaggtta tcggcagtgc tgtgccgaaa tttgttaagg
    16861 agggattcct atgggagaac tctataaacc cggcgaagac aacaaaccaa aaggaaccta
    16921 caaagaagtg ggtcctcgtg gtggaaatgt ccaaggcgga caagaagtaa aaattgatcc
    16981 aggcgaccga ttacccccta cttctcaaaa aggaaacaaa tggactaaga aatagcttcg
    17041 tccaaagccg gcttaaattg gtcggctttt tcctttttct ccaaaaaact tgaaaagcgg
    17101 tctttttacg aaggaaggac agcaccgttc ttctcaagcc ttactcttta atcttttaga
    17161 gtaggggggc taccttcatt tcgctgcaaa cttatctttc aggagttgaa tacattttaa
    17221 cgatatgtga tttaggtttt ggtttcttct tcccgcctga tctctctgga tgctctctgt
    17281 tgtgacaagc tacacagata cattcaaggt tatctacgga ccagaacagt gacaggtctt
    17341 ccctcgcctc gactatgtga tggatgatcg tgccccttgt gttccgccct cgacgcttgc
    17401 actcttggca catgccgaag tccctagcta ttactacttg ccttaggtct cgccatcgtt
    17461 tggtcttgta tagtttgtct atttcgtctc taggtctaac ttctttcatt tacatatctc
    17521 tcttgtgtcc gattgttttc ttatctggat acttatcatt aaagctagaa aagtattgaa
    17581 tcgtgatgtc gttcgctcct ctatcatcat tagtaaaatc atcagtcttc caatgatacg
    17641 agacatctac taatccttta ggcaattcat ccaacctctc acccttgtac caaacctctg
    17701 gtactgagtc agtatctttt agtttgatct ctagaaggtt aggttcttgt ttgttattca
    17761 gatactttag gctttgttca agcgatttca ctgatttaac tcttgtttcg cctgtcaaag
    17821 gaataatatc ctcgtgttca tcactatcca aataatcatc ccgaaagtat tctaagctaa
    17881 ctttataatg tttggctatt gcacatatct tattaaaatc aacgcgttgc ttttttccag
    17941 actcaatatc agataaccat gattttgaca ctccagtttg tttaactaag tcgttcattg
    18001 tttcgttatt aagccgtctc aatttatata tcttttctcc tatgtgcatg tgcattactc
    18061 ttcctcctta atccacttaa agaacttgaa ccacgcgagc gtctgctcct tactgctacc
    18121 atcaggactg ctatggctct cagtcttcaa tacatgtata gcaacatcat ctacagtgta
    18181 gctgtcagga agtttattct tagaatgcat gtagcaacgt ttcaaatgtt cgaggtaact
    18241 catctatcta tccacctctc aatgttttgt tggatatact cgtctttcca atagccatga
    18301 ccgcaatata tcagcttgca tttatccact tcgtttggtg tagcttctct tagcatttcg
    18361 acaatagagt acttcccttt gatttgtaca gaacgcacaa cacgcactga acaatcatca
    18421 atggttcgag gatattcatt agttagcgat acataccagt agtttctcat ttggcttttc
    18481 tccttctgcg aaaagaaata acttcattgt tttcctttcg tttatatgta tcgctcttta
    18541 ttggtcttct atactttcgt actatctcac cgttaccgtt ttgcacagtg attacttcat
    18601 acttctgttc taagtattgt ggtctataca tcgttgttac ctcctttatg taaaataaaa
    18661 agaccactca acgagtgatc taatatgtaa tagcaaccta cacgatgcac aaaacgcgta
    18721 cgaaattgcg cacccctata tttttaaacc gccgatgcct cggttgccaa agtcactggc
    18781 aatgaatcga acattgcata gttgccgaag cattgaccta gcacacatgc ttagcgtcta
    18841 ccctttccgc cacagtgaca atataaaaat ttctttctta gttactacta tcttttattt
    18901 tgcccatttt taaatccaat catatagaca ttaagacaaa gcgcaaaaat tgaaattatt
    18961 aatggaatca tttctcttcg ctcaccttta gttatcgtgt gaataattaa aaaaacaata
    19021 gacagcaacg gatgatagat aataagaaca atttagaagg agttaaaatt cacatcctta
    19081 ttcttaatat ttccgttgct gtctatcgaa gcttaattgt gaaacaataa taaaacgatg
    19141 ttccttttat tattattttg tcttagacct atcactaatc tttcgacact accataatat
    19201 cactggtaaa tagctaaaaa ccgccatcat tccgccaaaa agccgccaaa ttatttataa
    19261 gcaattattc ttccgtgttt atatgcttct gcaaactcta ttagagcttc cgacttcatc
    19321 cgttgtatac ttctttctga ataacccact tcacggctaa ttctgtagtt tgagaagcta
    19381 tctggcacac aaaagctata gtagagtatc tgacgactaa tcagactaag agccatcaag
    19441 gctgctagaa tcgcgtctct ctccgcttct atatccatca tctgaatgat tgcgtcttct
    19501 gccttattgc cgtgcttcgg cgccttcggc atatccgtaa taatcggcga cttaatatct
    19561 atcaaagagc gacctgccat ccgctccaaa cgccgaaagt tcttcagcac atctctcgca
    19621 ttacatcttg tctgtttgaa atctacctct cgtaacaatt gcatcaagtc aaaccgctcc
    19681 tttatgtgat ataataaact tgtggaattt attatatcag cagcttttta tttcaatact
    19741 cttatatagg cagtcagtgg tcggctgtct tttttatatt ttaatgagaa gccttactta
    19801 tttttttatc tttattacga aaaatgatat tatctattga taataaagcg tataggagat
    19861 ggttgagtga ctatgtggag catgctgtta ttttggattc ccgtttgtat tggtatcgtc
    19921 gcattttgtt actttgtcaa acactctaga acaaataagc tcctcatgtt atctttttta
    19981 cctatagtat tttttattgt acaaattgtt aaatatacct atattgaatc gcaagaaata
    20041 ttcatttttt atgtggtagg tttatttatc tctgtggtct ttttcataat gatactttcc
    20101 tatttttata aaaaataaat ttttctctta gaagtacatt ttttcgctgt ttatataacc
    20161 tccatatcca ccaatctcgc tactgctaaa ttctctttgc ttttcgctaa ccacttgtca
    20221 cattccatcg tgttttcaat acgaatgatt gctgagtgat tatagagatg ttctacatat
    20281 ccacaaaatg gatagatgaa tccttctgct tcacagcgaa ccatgtcacc gactttgaat
    20341 tttggtttct cacgtgtttt agggttcttt gtcggcatat ctagcattaa accgccgata
    20401 ccatgactgc tggagtaaaa tccgtctttt agtttcattc tttttcctcc catttacgat
    20461 catcacttaa tatcgaaatt ccaaacttac gaatagcgcc gctcgcatca gcaacacact
    20521 gacttgccac tttatatgtt tcttctgctg aaattccata ttctttttca aactttgtct
    20581 ttagtacatt cagttcccgt tttcttagtt ttgttattct gcggtgtctg ttgttcattt
    20641 tgtttaactt tcttctctaa tccatctcgg acactacgag caaaaatttc tatgttttgc
    20701 tgcgcctttt ctcttgtaat agctcctctg ataaccaacc taaccagttc tataagttta
    20761 tctttagtta gtttattttt attcttctca aaatcttcgg acaacttttc taatttagta
    20821 atgtatgggt cgctcatcct tctaccacct catccactgg cacagcaaac ggccagtatc
    20881 tttcatcaat tgctttgatt tgtttttcag ttaattgaaa tttttgagta acgtactgtg
    20941 aaaattcatc tgctggaact aatatgacaa cgtttgtatt gctgaatact ttgacaagat
    21001 atctaccatt gattattacg caatacaacg gctctttctc gagctcgtag ccaaacagcc
    21061 atgcacgcat ataaatttca ggatgatcaa ctagccaatc aattgcttct tcatgctcac
    21121 cgtctttagt tttgcgataa taccaatcat ggaaagttat caataaagct aataaatcaa
    21181 catctgttga ctgacgataa tagtcgagta gttccgccac aaacttaggc acaactggct
    21241 tctgcggttc atacgatggg aaacgtttaa tcgtttctaa agcgtcacta ttagatccca
    21301 caccaggtat tttcattaat tcatcaatca atgcttgttt atcaattaat acttttttat
    21361 tcatcgctgt cctccaaatc actcgacttc acgaatacac catctaccat ttttcctgtg
    21421 cgtcctttga tttcgttgta tgcttggttc agacactcgt acaaatccat atcattttgc
    21481 atagctaaaa taatcaaggt tactactacg tctccaattc cgtctcttaa accatattca
    21541 tcttttctag ctagagaagc ggcaacttcc ccaatctctt cgatcgtttt taacatttgc
    21601 ttgctggaat cagcttgatc caatccctta tcttttgccc actgctctac ttttgtgatt
    21661 agttcctcca ttatttcttc tcccaatgtt taaattgacg acctttcgaa tcaacgttct
    21721 cgcgtttagc tctatcccag ataatgtttt tgcttaatcc agtaatttca gataactgtt
    21781 cagcagtacc tgttactaga attcggtcac catgccagat tgcaattttt ctcggtgttc
    21841 tccgtttggt tttttcactc cacattgatt taccgagctt ttggacttct gcaactattt
    21901 ctttgtcttc ttgccaattc tcagaatgtg tcagttcgat gattcgtttc attgctgctt
    21961 tcttatccac gctcattcct ccaatcgatg gatttccctt cttaaattct ctatgtgcaa
    22021 atcgattgcc ttcctcgccg tttcattgac catcactgcc tttgtccgtt ccagatcgtc
    22081 aatctcacgc tgaaggcttc gaatacgcat ttgaatcact tcttctgttg tcatgatgat
    22141 tcctccacaa ttttcaatgc ttcttccact gatcgtgcaa caccgtatag tacaggttga
    22201 ccgtttaaaa attcagcaaa ccttttttga tcttcacgca acttaccgcg ttcatttttt
    22261 acttctatat aaattgcttt cccatcagaa ttacgatgtc cacatagatc tgggaaccct
    22321 tttggcatcc cgtaaaattg ccgcccttcg atcgttgtca cttgtcccgc attggatcga
    22381 aaaatcgtgc aaccatgttt tgataaggca attctgatct cgtcttgtat ttgatgttct
    22441 gatttcaatg taaccctcca gactgtttaa tcgttggtat caaagcattt aggaagattt
    22501 tggtggagag tttggagggt cagacccaaa aacctattct tttttatata atttactttt
    22561 tattttttac tttaatactt tattattttt ttaaaaccct ccagaaagaa agaaaaatat
    22621 aatataaata ctgatatatc aacgtttcta agggttggag ggtttcgttc tcaaccctcc
    22681 agaaccctcc agatttattt aaaaagttct ctaacgttat cgtattttct tggttttaat
    22741 gtgattcctt tataaaccat aaatccacca gctttttctt tgctatattt ctttgaaatc
    22801 tctctgccaa acttcgtgtt agtgaaagta tgctcgccat tatctgatgc ccattcacga
    22861 taaactttgt ataattctcc gcctgatatt tttagtcctg gacctgtttc gcaacacgtt
    22921 tcgataaatg tacctatttg atccatttcg tttcgataat cctgactcgc tgcaacaacc
    22981 gactttggtt tctccaagcc ctctctctgc cacaacaggc aaccatcgat tgcccattta
    23041 aggatccctt gcaactccgt ctgcaattta aatttcagat ttttatcctt tttgtgatcc
    23101 gggatttgga cagtgaatgg aattaaattt aaccgtcgcc agatgccgtc atcggtccca
    23161 cggatgatgg gcttgtggtt cgttgccagc cacaacttga attcaggttc gaactcgaat
    23221 tcttttccat aaaggtgccg agccgtgact ttatcaccac cagtcaattg tttgaccaga
    23281 ccttcgtcca gtcggacgcc ttcattcggt tctgacgaag tgaccaaccg cgcacctttc
    23341 aatcgtgcaa tatcactgtt tgctgatgat tggctttgct tgaccatgat cgtttgtgcc
    23401 tgcatagtca tcgcatagtt tcccatcaat tcagaaataa tttccaaaaa taccgacttt
    23461 ccatttgacc catgaccgta gaggatgaac atacattgct ctctggtaga tccggtcagg
    23521 gaatatccga cacatttctg gatatatctg attaattctt gatcattgtc aaaaatctga
    23581 ttaataaatt cttcccacat aggacaatcg accgattctg tgtactcgac atttgaaaca
    23641 cgtgtaaaca ttttgtctat ctcatgctcg tgtagaagac cgtcatgcaa agacagatag
    23701 ccgctttgtg tgttgaacag cgttttatct ttgtcgaact cttccggcaa tacggatagt
    23761 cgatgtttca attcgtccat catagcgttt tttccggcat tgctgcgaga acgcttgacg
    23821 tgtttttctt tcgctttcat caaagcttct ttggtttcat cgtctgcgcc ttcagggatc
    23881 gttaacggtt cttttcccat gatgtctact gtcgtatcga tcattttccg aacttcgccg
    23941 gtattgtcct gtagccaaac tttcccatcg tagtaatacc aagatttatc aatgtacgaa
    24001 tatttgacta acgttccgta gatatcagta aaccgatccg cgttgccggt gtcgtcgtac
    24061 gaatagtatt tttcctcttt tggctgttcc tggtctttga taaaaatctt aaaatcagat
    24121 ttccgtttgg ggttgtagac ggaatttgta tcagcaattg ccttatttag tagagattct
    24181 ccgtaagttg ccgatcccct tttttggtca tatttgctac ggatcattgc agacgctctg
    24241 aaaatctcat ccattttttc aaagtctcta ccggtccaaa aagccaagtc gttggcgaac
    24301 gccatatccg cttcggattg cgaggaataa aaagcttccc aaccgccgtt cataaagact
    24361 ttgaatcttg ccccttggga agacgattca gcacgtttga taatttcttc aaccggtaaa
    24421 tcaacggtat tcatcagcgg attttcttct ttgaattgga tgattttttc atctccaacg
    24481 tagcgatcat ataggcgttt gatatccttt ggattcggct cagttatttc taaatatttt
    24541 gatgcggcat ttccagtcat aacgaagaat cggccgttct ggtacatttc tacgtcacct
    24601 ttcctgcgtc ttccgccggg caattctccg cgagcaataa tgtggatgcc agtacctgat
    24661 tgagaatact cagcatagga tctcatgctt tcgataaatt catagataat attttcttct
    24721 atatcacctg atttaaatcg ctcaacttca ccttcagcat tatcgatatc aatgccgaaa
    24781 taaggtggtt tgaaaaagaa ccccagtcca ctcattccgt agtgatcaat agcagcgaga
    24841 gcggtctgaa aatcagacca ggtactctcg tcattggatt tggctttatg cccgttgttg
    24901 gcgttataag ggatcttcgt gtgcttctgc cgcttttcat cccaaactag cttataaaca
    24961 caccattgtt tgagattttt aagctctttt ggaatttttt catacattga ttacacctca
    25021 attaaaatgg aagattgtca tttctaaccg ttgtcgctct tgaacgttcc ggtccgaagg
    25081 atggttcatc accatttttg aattggtgat tcattacgcc ccgtgtgttc gttttatccc
    25141 aagacttcac attgacgttt ttatatccat ttgactcttc agttttcacg cgtactgagg
    25201 cggttttcaa aacaaagtcc gccagcaatt catcaaaccc gttatatgat tttccgtctt
    25261 ccaactgtag cgcttgtgca attgccatga tcataccttc gttatatttg ccggtagctt
    25321 tggctttcca gatttttgcg aaaatgtgtt tattttggaa cggttgatcc acatcgttac
    25381 gaacgatcaa atcgatatcg ataaattctg cgcctgattt agttgcattt tctacagctt
    25441 tgtttacgac cacttcgtac gtaccgtctt tgatttcgtt cccttgttgc gcttttgaaa
    25501 agtctaagtt aaatcctgtc atgttaatca ttctcctttt tattttcata tttttctaag
    25561 ataggtttga aatatttttc ttctgctgca agtcgtgctt ggattgcttc ttctttggtg
    25621 ttgaaatcct tttgtaagac atattctcct ttgaaatata atcgtgcttt ccatttattt
    25681 cttcgtttat cccaattaac gccttttgtt ccaccgacag acaaagcctt aacgtaagtt
    25741 ccttcaacat ggtatttttc attagctttt tttaaattaa cgtagccact ctcttcgcct
    25801 gtcccgttaa caacacctct ttttatatta gatagagaag attcaaaaac ttcgttattt
    25861 ttatttctag cgattacaat ttgattgcct gaactatctc tttttccagt atcacctatt
    25921 attgttacgc catttattat tgaaccttga acatcttctg cttttttacc aaaaataccg
    25981 cccattccta caaccacccc ttcctcttag cagccatata agcccaacca ggtttaaatc
    26041 ctttagctct tgctatggca tataagtcct ctatactttc tgcttcatct tccgtcatgt
    26101 tgtaatattt attgttctca aaattcaaag taattttcgt ttctccgact ttcattaatt
    26161 cagccgattc atcgatttct aactctgact ttcgttcttc aatcggctgc aactctccgc
    26221 aatacggaca aatattatcg ccttttggcc gttcgtaagc accaaaacaa aacgcgcatt
    26281 gaacgataga taaatcacta tcagtttttg ttttcttttt tgtatctaaa ctccattcac
    26341 gatccatatc aggcaatcca aaacggttca cattacccac atggtcaatg atgattgacg
    26401 ttttatctgg tcggtaacgc atccccctca tcgattgctg aatgtacaat gataacgatt
    26461 gagtaggtct caacataatt acagtcgaac aatcaggaac atcaaaccct tctccgatca
    26521 aatcaacatt gcataggatt ttaatttcat gatttctgaa cgcttcgata atatctgcac
    26581 gttcatcttt tggagttttt gcatcgatat gtgttgcttt ataaccagca tcgttgaata
    26641 tttcagcagt gtgtttactt gcatcgatac tgtgacagta tgctattgcc tgttcacctt
    26701 ctgctaacgt tttataatgt ttcaacacgt cgccataaat agtattcttc actgccttat
    26761 ccattgattt ctttgtaaaa tctccagtcg aagctttctt taattcggct gtatcgatca
    26821 atttaggtgc ataatattca taaggagcta atctatgatt ctcaatcaac catttagccg
    26881 atactccttc aattagcaag tcgttcacat cccccaaccc actaccgttt aaccggatgg
    26941 gtgtcgcggt aaaacctaat cgcggaacgt ccgaataata ctcatagatt tttctgtagg
    27001 acgctgctaa cccgtgatgg ttttcgtcag tgatgatcag ttgtggtttc ttgatggttt
    27061 taagatgtcg tacgactgtt tgaaccatgc cgaaatttac aagctgatta tctacgccca
    27121 tcttttgaaa cgtatctttg atctgatcaa tcaattcacg acgatggacc aagaacaaca
    27181 ctctgttgcc ttttcgtgtg gttcgtttag cgatctctgc aaccatgact gattttccag
    27241 aaccgcacgg tgatacgata catggtgcct tgtaaccatc aacataggct tgtcttgcac
    27301 gatcgactaa atcattctgg tagtcgtaca attccatcta aaatcagctc actttgctta
    27361 cagccagatc tattatccaa ttgatttttg gcataggttg aatctgtggc ttgtaaaata
    27421 aatccgcgtt catcgtcttc ctttaccatc aatcgaccaa caacgtcaca taatcccaaa
    27481 atattgtttc gaatctttcg attgatctgc ggcaaagcga tgttgtaaga agatccatcc
    27541 gaatccgtcc acaaatcgat ttcttcccat gcggtccaga taaggttgct gtctaaattt
    27601 ttcatatagc gtaggctgtt caccattcta aattgcatat attgataatc gccttgcgaa
    27661 ggaacgccgt tgttttttcc ttctgcgcct aaactggaca gaatacaccg ttccaattcg
    27721 ctgacattat cgacaaccac gttgtcataa acacctacat aattggtagt taaatcagcc
    27781 aacgtgttgc cccagtcgtt ccaggtatct tcgttgtcga tatatacgat atcgacattt
    27841 ttctcacctc taaggacttt tgaagtccga tcaatatcaa ggatcagtgt tttccctgga
    27901 aaatatttag ccgttgaagt tttacctttt cctggagcac cgtagatcaa atatgttccc
    27961 ttggtttgtt cgatatccgt cgccttctta atctgcatca aaattctcct ttctattggt
    28021 taaaaaagtt tttcgattgt cggtatgctg cattgttgat ccactatctt cttcaactga
    28081 tatagtgatt cttttaatca ttttgtattc actctcctac tctggttcgt gcgcaataat
    28141 ttcaacaccg acaatataat cacctagtct gtcgaattca tcttctacaa gtgtactgtc
    28201 gcctttatcg ttagtaagtt ccatagagaa ccaatcttca tcaaggtcac ggaaattaac
    28261 tgggttatcc tcgaaattag catcatatag atcatctgaa tcaatagcta ttaatgataa
    28321 acccttagtg ttaccgccca ctttgtaagt aacatatcct ttgtaacccc aaatcataaa
    28381 agaaacttta attgtgtgtt tagcccatga aatatttggg tcataaatag tcaactcttt
    28441 catttcccca actcccctac cttttgatcc gtatactgcc gtaactcgct cacgcgctgt
    28501 tctaactgct ccttgtcgtt ttgcactgtg gatagttgtt ggcgcaagct atcggcttcc
    28561 tgttgctttg tagcgatctc ctgttgcttt tgttcgactt ctcgttgctt ggcttcaatt
    28621 tccttctgct tgtccgattt gatttgctca atttcggctt tcagctgctc ctgtgtgcga
    28681 gtgttgttgg atagctgtga ttcaagttct gacacacgtt gcgatttcgt ttgaccgtat
    28741 tgtaggactg tgttgaaatt tgctttgatc gtgtccaaat cttgaaacgc attgcttgct
    28801 gcgtagccga taacgccgct acctagtgct agtccgatga ttgctgttgt ttttgctagt
    28861 ttgtttttca atgttgtttc tccttttttt gctttataga taatttagtt cattaaaaat
    28921 tcattcccac gattaaaacg gaagcctaga aattgcaaac aatgtaaatg caagagctac
    28981 tgttatgctg taaattgcgt ataatttgta agactcaggg cgaagcttct tcatgatata
    29041 tatacaaacc ggtatgcacg accaaatgaa tgttacgcag actattactt gtaatacaac
    29101 caccctagcc actccttccg tgtggggtta tttgtctaaa tacaattccg acaaaccaag
    29161 caagtcggcg ataaaataaa gatgttcttt cgtcaaattt tgaatgtcat ggacagttgc
    29221 tggtttgccg tcaaccttta ttcctttagc ttccgcgatt tcgatagcag ctttcaaagc
    29281 gtcttttacg ttttcgtgtt ccattatttc tcctccttca tcatcttatc ctcaaacctt
    29341 ttgtttggac gagttcagca ccaggaatat ctccgtgctt cagttcctcc ttcaattgct
    29401 ttttatccaa tttgggaggc acaggggtaa agaatccttt tggaattaag ttctcattga
    29461 ttacattgac cgatactgga ttattttgaa ttccaatgtt gaataattca cctttaatct
    29521 tcgttttacc agtcttttcc atttcctctt gtaaatagtg cttgatactc ttagcattgt
    29581 tcaaaagcga tgtcttacgt tcctgcagac gtttaatttc actatcgatt aactcagctt
    29641 tcccttctac ttctttaact atttttgcta agttttctgc cttatactcg atcgcttcat
    29701 taatcgaatc gagagtatcg cgaagaattt cttcatccaa ttgttctgcc agttccagga
    29761 ctttgatata tgactcgctg agttggtaaa gagttgccat tcttttgtgc ctcctttaat
    29821 aattttgcaa tttgttcaaa agctaggatt gcctcatcta aatccaattc cacagaatca
    29881 tcaatttgtt cgaaagcaag gtttgtttct tcaatatcac ttgcttgata gataccaatt
    29941 tttccattgt cataaagatc aaatactaaa attcctgacg catctatatt gcgcagtttg
    30001 tattcgtctt ttaaaaagat gcggtctagt gtatccgttg caattagcat ttacggttca
    30061 ttcctttctg tggtaaaata tagaaagata gtttatttcc ctgacacgat catgcttgcc
    30121 ggcgttcgtg tcttttttta tttttcaaaa ttactaattc ttgcattatt tcttctctcc
    30181 tttttgatat aatttgagta aaaaggtggt gaattacttg ataaaaattt tgagcgatta
    30241 ccaagtcgct attactttaa tcatttctat ttcaggattt tttttatccc tctataactt
    30301 atttaaagat aaaagaaaaa ttacgctctc ctatttttta gttaagcatg atagaagtaa
    30361 tcgaatgatt cttactggcg taattgcaaa cccatcaaaa atgccaaact caattatcga
    30421 atgtacgtat ctttacaacg gtaagaaaat taattgttca cattatcacg ccaatggttt
    30481 tgatatggga agcattcata aaagtagcct tttatctcct ataccgttgg cacaagcaat
    30541 ctctcctggc tactcagtcg ctttttcaga agttttagat atgaaagata tattacctgg
    30601 tgaaaaactt gtaatggtca taagaacagc taattatcaa aaaaaattta agttaaagct
    30661 aaaagactca ttttaattga aaaatttttc tttaataatc aaatacaaat taattattat
    30721 tgatccaatc ccacaaaaca taattaacag aaatacaata tcgtccttac tcattagtca
    30781 gtccctcccg actggctttt ttgttttgta ctcagcttca tccagcccta taaaaatcca
    30841 aaccatgtac acaatcgttc ctatcaacgc ttgtctactt ccccaaagcc ctaaagcata
    30901 gacgattagc ggtgcgctga atactaatgc tctgttgaat ttacccatta accttcacct
    30961 ctcaaaatgt tctgtttttt ataaatcaac taaatgcttc tcgataaatt ctttaggtgt
    31021 tacctttctt gtgcgtaacc tgttatagga tttgaaagac aaaaatttat cgtataattc
    31081 tgtattgatc caaacttctt gtcctgtgac ccgttcatac gccgctgaga aaattgctgt
    31141 attttttagt tccgacattc gacgttgata agtagatgga gaataattat atttttttac
    31201 aaaatcttgt ttttttagtt ttgtcatcgc ctaccccccc tatcggatgt ccaatatttt
    31261 tttcactgtt tcgatatgct gttgtgcttt ctttccatca cgattgccgt ttagaatatc
    31321 tgataaataa gctcctgaaa taccgataag cgcagctagt tctttgaaag tcattcttct
    31381 ttttctcatc tccgctcgaa tttttaagtc taaattctca gacataaaaa tagctccttt
    31441 ctaaacaaat aatttgtaag ctaaaaaatt agctaaatcg ttgacaccta ttagctttta
    31501 agctattatg aatacatagt taaataagac ttataaaaag cctctaaaat aacatttcta
    31561 agtttggcga ccgagagaat gttttaaatt agtagagttt tttgttgctc ttatttagct
    31621 aacaatttag cttacgaatt aaatatacta gcttaaaagc taattgtcaa ccaaaaatat
    31681 aacttttaag ctatttattt tcttttcagc tttgaaaggt tgataataat gagtttagtt
    31741 actaagatta aagaattagc agacgaaaag catgtgacta tagcagaagt agaaagacag
    31801 gtgggcatct ctaatggaca aataagaaga tgggataaag cctcgccaaa atctgagaac
    31861 ttaaagaaag ttgctgatta ttttggtgtc acaactgatt atttattggg aaataataat
    31921 gttcccaagt gggctacaaa agaggaagtg gttgaacttg ataaactact agactcaaat
    31981 gttaatatgt cttatggtgg ggaaacattg acacccgaac aaatacagcg cgtaaaagat
    32041 atcctgatag cgactttctg ggatattgtg aaagaagaca aagaaaaagg caaaaagatg
    32101 tgagcttatg gagatggata cgattaattt agtcgaggag ttgaagcgga aataccagtc
    32161 cgctaatcct ttttatattt gtgaaaagat gggcattaaa attcaatacg ttccttttat
    32221 cgagaatccc aaggggcagt ttcaagaaat tagagatcgt gcgataatct ttttaaatga
    32281 tgaactgcga gactctgagg aaagattcta catttgcgct cacgaattag gtcacgctat
    32341 ttttcatcgt ggcttatcca gctattatgt atcaacaaga acatctagaa gcaaatctga
    32401 aagcgaagct aattgctttg ctgctaatct cattgtttct ctttataaag aagataatga
    32461 tcaatatcct aaaaaaatcg aggaattaaa gaatctttac gggcttccag aaagcgctta
    32521 tcgttttctt atataaaaaa gcccgtgtta gcacacatat tacaacgaga aagaggaatt
    32581 ataaaatgaa aaaagttagc gttatgttgt tgttaagtac tgctctgcta ctttcagctt
    32641 gttcaaataa taaaaaagct gaatcaacag ataccacttc taaccaagaa acaaaaataa
    32701 gtaaaacaaa agaaacaact gaaaccagtt catctactag caaatctaca tctaaaacag
    32761 attctagttc aacagttaca agctccaacc aagctacggc ggaacctagc ccaacagtta
    32821 taagctccag tcagagtaca atccaaaccg cacctcaaga agaaacatat gaacagatga
    32881 aacaacgcac tttacagtca actccagctg atcgtgcaaa ttggtccaac aaagagtggg
    32941 aagctttcgg cgtggccctt tatgaaaatg gattgactac agatgatgct ggcaatatta
    33001 tcagtcaaga tcagaaagaa caacaagcag catctcaaca gaatccagaa gaccaacaaa
    33061 caagcgctca gcaagacgct gacactttat cacttactga ttttgttaac aaatacggga
    33121 tgtcgcctgt tgcatggaaa gtacagaatg gaatgtctga agaagaagca ttgcgtacaa
    33181 cacagcaaaa gacttccggt gaagttcaat taggattttc taaatacgga attcaataat
    33241 acatttttat gccctactat tttgcctata atctctaaaa aagttataaa gaaaaaagcc
    33301 cgtgctgcaa cacggactca tacctcattt ctgagatcac aaatatatta taacaagaag
    33361 cgagggatat ttaaatggca aaaaaagtta tgggtcaaga tgggaaaatg tataaagtta
    33421 agaaaccgtt ttataaacgg gtatggtttt ggttgttagc ggttgttgtg gtgtttattg
    33481 ctataggttc gcaaggaggc agtgatgatg ctaaaaatac cgtcgctgaa acaactaaag
    33541 aaagcgtgac agaagtgtct tctgcagaat cggtagcaga atctacagtc gttgaagaag
    33601 aaactgaaac tactgaaact actatagaag aagttactca agaagaaagt gttcctcgtg
    33661 aatacagaaa tgcattgagc aaagctgaaa gctatctagg ttgggctggt atgtctgaac
    33721 aaggtttgcg tgaacaacta gagtttgaag aatatccaag tgatgcaatc gattatgcgc
    33781 tggctaatgt tgatgtcgat tacaacgaac aagctttggc taaagcggaa agttacgatg
    33841 attgggcatc aatgtcagat tcgcaattgt acgatcaact tatatttgaa ggttttacaa
    33901 atgagcaagc acaatacgct ttagataacc taccacaata actaacaaaa acacgcccct
    33961 ccctcgccaa agtttgtgga cgtgatgaaa aataaacctg ctataatcgg cttacttatc
    34021 tattcctatt atagcaacaa ataggagatg aaaacaatgt ggatcgaaac taaaactgat
    34081 aaaaacggaa aaaaagtata taaatataat gagcgatata ttgatccaaa aactagaaaa
    34141 agaaaaaaag tgagcattac ttataaaaat aaatctcgag aaactcagaa agtggcattg
    34201 ctagagttaa ataaaaaaat tgatataaaa ttaaacgaaa aaacacttca taagcctgat
    34261 ctaacatttc atgagcttgt tgaagaatgg ttagttatat acaaaagaca agttaaggaa
    34321 tctacatatt atcctacgaa taatatatta aacactataa agaagaagat acctgagact
    34381 tacatcgttt ctggtattaa tacaatagat ttgaataata tttttgaaga catgatatat
    34441 aaagatgact tgtcaaataa gtacgtcagt gtaattaaat ccaaattgaa tcttcttttt
    34501 tcatatgcta tgaaaaaagg ttatgtagaa aaaaatccta tcgatgaagt agttattgat
    34561 tataaaagag agtcaaaaac gataaaaatt aaagataaat ttttagaaga tgatgaatat
    34621 aatagactag tagatttcac aacttcacac aataaaagat attctctcct tttccagtgg
    34681 ctatatttga ctgggatgag gtctggtgaa gcaatcgcat taagtaaaga tgatgtacac
    34741 attaccaata ataatgcatc agtagttata aatgggacga tgatgtatag agaacgttca
    34801 atagctgata tgaaaaaatc tgattctaca aaaacagctg ccggaatgcg agaaattgat
    34861 ttaccaaaaa aagcgatagc tatttacaat gagcttctag aattaaatcc aaatggtcaa
    34921 tttctatttc aaacaacgaa aggaactcct ttccaactaa cagcaattaa cacctatttg
    34981 agaagtcata aagctgacat gaagattgat aaaaaactta gttcacatat ttttagacat
    35041 acccatattt caaaattagc ggaactagga actcctctgt atgccattca ggatcgcgtt
    35101 ggtcacgaaa atagtgatat cactgaaaaa atttatttgc atgtgacaaa aggagtaaaa
    35161 gaaaaattga aagaagatat agaaaaactg taacttgttg cccctttttt gccccttttt
    35221 attaatcaaa aatgtaccaa atagaaatcg ttaatataaa aaaacagata ataaaaaaag
    35281 aacccttgaa taccaagggt tctttctctg tctgataacg atgattaacg acggatttct
    35341 ttgatacgag cagcttttcc gtgtaatgca cgtaggtagt acaattttgc acgacgtact
    35401 ttaccgtagc gaactacttc gatttttgca acacgtggtg tatgcaatgg gaatgtacgt
    35461 tcaacgccca ctccgttaga aactttacgt actgtataag tttcgctgat tccagcaccg
    35521 cggcgtttga taacaacacc ttcaaataac tggatacgtt cacgagtacc ttcaacaact
    35581 tttgcgtgaa cacgcacagt gtcaccaggg cggaacgctg ggatgtcaga acgtaattgt
    35641 tcttttgtta attcttcgat taatggattc atggttttct tctccttatt ccaaatattc
    35701 ttatgagctt ttctcacagc ggaatatcgt aatagttaag tgcttttgca ctcaccataa
    35761 aatactaaca tattatcaac ctactgtaaa gaagatttta gaaaaagtca cttggcttca
    35821 tctgctgttt tttcttgttc ttctttcttg atttcttcta aaaatttcgt catttgaggt
    35881 gtccattcaa gtgtttccaa aagatcaggc cgacgttgat aggtccttct tagtgattct
    35941 tttaattgcc attcttcaat caatttatga tttccatttg tcaatacttc tggtactttc
    36001 atccctttat attctgccgg gcgagtatat tggggatgtt ccaataaacc ggttgaataa
    36061 gaatccgttt gagctgaagt ctgattccct aacacatctg gcaaaagccg aactgttgca
    36121 tcgatcatga ccatcgcacc taattctccc ccagtaagga cataatctcc taaggaaact
    36181 tcatctgtca ctaatgtgcg gatacgttca tcatatccct cataatgacc acaaatgaat
    36241 actaagtgtt cttcttgtga aaattcttct gccattttct gatcgaatcg tttaccagct
    36301 gggtcaagaa gaattactct ttttttgaca tccggtgcag ctttttcaat ggcttggatg
    36361 ttatcataga tgggctggac tttgagcagc atacctgctc caccgccgta tggataatca
    36421 tctactgtct gatgtttgtt atctgaataa tcgcggaagt tagagatatt gatatctaat
    36481 aatcctttat ctacagcctt accgatgatg gattccccca taggaccttc aaacattctt
    36541 ggaaataaag tcaatacatc aatcttcatc gtcaatcagt ccttctggaa tttctacacg
    36601 gaccactcca gcttctaaat cgacttcttt gacgacagaa gcgatatatg gaagcaatat
    36661 atcagctttt ttcggacgtt gaacgaccca aacatcattg gcacctggtg acaagatttc
    36721 ttttacttta cctaactcag ttccatcttc taatacatgc agaccgatga tctcatggta
    36781 atagaattca ttttcagcta gatctacaga gttgtctttt gacactttta atatgccatc
    36841 ccgatatttt tccacatcat tgatagaagg atgtccttca aaactcaata agtcaaaatt
    36901 tttatgtttg cgatgacttt tgactgttaa ttccacaggt gcttttccgt cttggaatag
    36961 tgttagcacc gttccttttt tgtaacgttc ttctgggaaa tccgttgttg agataacacg
    37021 gacttcgcct ttgatacctt gtgtgtttac gatttttcct acattcaagt attcagtcaa
    37081 cttatatccc catttctttt ttgtctgttt tattttagca tgtgtgaaga ggcaattcta
    37141 gttttctttt aaggtattaa gccaaaatta tgcaaaaatg cggcgtgcta tttttgatta
    37201 cttcctgtga cttggagtta aatgatgggc tcagatcagc gcgctgattt cacaacctct
    37261 tcatagaaac tgccatcttc aacgcagaca taggatcttg atgagtgatc gtataggcat
    37321 ttttcggttc ttgccagctt acttctacgg ctcgattcgt cgtatcaccc atatcaacag
    37381 taattttacc aaattgttca ggtgctggta gactgttttc ttccaaataa gctacgattt
    37441 ctttagctaa tagtaaggga tcttggcctt ctatattatt cccacggatt cgaatacgcc
    37501 agtttccttc ttgccattca agaaaacttg aacctgctgc accttgctga taccctgtga
    37561 ttcgagaacc taagtccact tgctgaccat ttgtgtcgat ctcaaatggc tgcaaaactt
    37621 ggattgtttc ttgactagaa gcaaacccat attgatatag ataggttgca ataggcgttt
    37681 cttgattcaa ttcgtcagca ttcaacccga ggggacgatc tgttctgtaa tataaaatag
    37741 aataaccttg ctttgtatgt gtcgctgcga tattgagata gcctgaagag actggtacat
    37801 ctagaggcat gggaacattt ggctgttgtt ctttcaactg gtctaaagca gtctttttct
    37861 cattatttga ggtagccatt gtttgttcag tggtggaagc cgttttggta ctactttttt
    37921 ctggactggt aacagtttca gatatactgc ttgatagatg tgtattgtct gattcttgag
    37981 taaccgaact acaagcgctt aacaatagag caaatggaat aaataacatt ttctttctca
    38041 ttggctgttc actccctcct cctataagga tacgctttct tgcttgtttt gccaaataat
    38101 catttcttca attaataaaa aaaacaaaaa agctgcactc gaaaattcga gtacagcacg
    38161 ttta
//
LOCUS       DBBGRF010000025        37170 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000025 DBBGRF010000000
VERSION     DBBGRF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.025"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..768
                     /locus_tag="ACIZD4_001453"
     CDS             <1..768
                     /locus_tag="ACIZD4_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen binding domain-containing protein"
                     /protein_id="HGC5990395.1"
                     /translation="ERSQTAVVELTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVE
                     LTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLA
                     PGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSG
                     NKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1121..1969)
                     /locus_tag="ACIZD4_001454"
                     /pseudo
     CDS             complement(1121..1969)
                     /locus_tag="ACIZD4_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2122..3234
                     /locus_tag="ACIZD4_001455"
     CDS             2122..3234
                     /locus_tag="ACIZD4_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC5990396.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3312..3605)
                     /locus_tag="ACIZD4_001456"
     CDS             complement(3312..3605)
                     /locus_tag="ACIZD4_001456"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGC5990397.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3773..4087
                     /locus_tag="ACIZD4_001457"
     CDS             3773..4087
                     /locus_tag="ACIZD4_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGC5990398.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4108..6087
                     /locus_tag="ACIZD4_001458"
     CDS             4108..6087
                     /locus_tag="ACIZD4_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC5990399.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6100..6426
                     /locus_tag="ACIZD4_001459"
     CDS             6100..6426
                     /locus_tag="ACIZD4_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGC5990400.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6442..6960
                     /locus_tag="ACIZD4_001460"
     CDS             6442..6960
                     /locus_tag="ACIZD4_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990401.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6960..8312
                     /gene="celB"
                     /locus_tag="ACIZD4_001461"
     CDS             6960..8312
                     /gene="celB"
                     /locus_tag="ACIZD4_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGC5990402.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8396..9901)
                     /locus_tag="ACIZD4_001462"
     CDS             complement(8396..9901)
                     /locus_tag="ACIZD4_001462"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGC5990403.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9993..10583)
                     /locus_tag="ACIZD4_001463"
     CDS             complement(9993..10583)
                     /locus_tag="ACIZD4_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC5990404.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10762..12408
                     /locus_tag="ACIZD4_001464"
     CDS             10762..12408
                     /locus_tag="ACIZD4_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC5990405.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12457..13176
                     /locus_tag="ACIZD4_001465"
     CDS             12457..13176
                     /locus_tag="ACIZD4_001465"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGC5990406.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13655..14602
                     /locus_tag="ACIZD4_001466"
     CDS             13655..14602
                     /locus_tag="ACIZD4_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990407.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14614..15534
                     /locus_tag="ACIZD4_001467"
     CDS             14614..15534
                     /locus_tag="ACIZD4_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990408.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15575..17032
                     /locus_tag="ACIZD4_001468"
     CDS             15575..17032
                     /locus_tag="ACIZD4_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5990409.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17377..17991
                     /locus_tag="ACIZD4_001469"
     CDS             17377..17991
                     /locus_tag="ACIZD4_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGC5990410.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17984..19708
                     /locus_tag="ACIZD4_001470"
     CDS             17984..19708
                     /locus_tag="ACIZD4_001470"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGC5990411.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19705..21156
                     /locus_tag="ACIZD4_001471"
     CDS             19705..21156
                     /locus_tag="ACIZD4_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC5990412.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21629..23782)
                     /locus_tag="ACIZD4_001472"
     CDS             complement(21629..23782)
                     /locus_tag="ACIZD4_001472"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGC5990413.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23784..24830)
                     /locus_tag="ACIZD4_001473"
     CDS             complement(23784..24830)
                     /locus_tag="ACIZD4_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5990414.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24980..26269
                     /locus_tag="ACIZD4_001474"
     CDS             24980..26269
                     /locus_tag="ACIZD4_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGC5990415.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26282..28984
                     /locus_tag="ACIZD4_001475"
     CDS             26282..28984
                     /locus_tag="ACIZD4_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGC5990416.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28969..29826
                     /locus_tag="ACIZD4_001476"
     CDS             28969..29826
                     /locus_tag="ACIZD4_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC5990417.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29897..30754)
                     /locus_tag="ACIZD4_001477"
     CDS             complement(29897..30754)
                     /locus_tag="ACIZD4_001477"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGC5990418.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            30965..33136
                     /locus_tag="ACIZD4_001478"
     CDS             30965..33136
                     /locus_tag="ACIZD4_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HGC5990419.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33204..33545
                     /locus_tag="ACIZD4_001479"
     CDS             33204..33545
                     /locus_tag="ACIZD4_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HGC5990420.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33821..35575)
                     /locus_tag="ACIZD4_001480"
     CDS             complement(33821..35575)
                     /locus_tag="ACIZD4_001480"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990421.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35586..36422)
                     /locus_tag="ACIZD4_001481"
     CDS             complement(35586..36422)
                     /locus_tag="ACIZD4_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HGC5990422.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36424..37107)
                     /locus_tag="ACIZD4_001482"
     CDS             complement(36424..37107)
                     /locus_tag="ACIZD4_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HGC5990423.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11989 a         6538 c         7618 g        11025 t
ORIGIN      
        1 gaaagaagtc agacagcggt ggtagaattg acgaaagcaa accgacttac accaggcggt
       61 gtcgtgttga caaagatcga tgaccaaagc ggggaagtcc tgcaaggagc tgtttttgag
      121 ttacaagatg ccaatggaac cgttctgcag tcaggtctaa ccacaggagc agatggaaaa
      181 ctggcgattg acggcttagc accaggagtg tatcagctgg tagaaaccca agcgccaacg
      241 gggtatgaat tggatgcgac accaatcgag tttgagatcg aaagaagtca gacagcggtg
      301 gtagaattga cgaaagaaaa tcgacttaca ccaggcggtg tcgtgttgac aaagatcgat
      361 gaccaaagcg gagaagtcct gcaaggagct gtttttgagt tacaagatgc caatggaacc
      421 gttctgcagt caggtctaac cacaggagca gatggaaaac tggcgataga tggcttagca
      481 ccaggagcat atcagctggt agaaactcaa gcgccaacgg ggtatgaatt ggatgcgaca
      541 ccagtaactt tcaagatcga aaaagaacaa gaagtggcga tctttttaac aaaagagaat
      601 agaaaagttg ctgatagctc agatataaga ggaaacaatc caacaagcag tggaaataag
      661 catcttccaa aaactggaga aaccatcatt agccagttta tattgtcaat attgggtgtg
      721 ctacttgttt tcatcagtat aaaatttaga aagaaacgaa atatatgagc taaaataaaa
      781 aattgaataa gcatagtttt taaaatcaac tagtacccat caattgaatg gaaactaccg
      841 attttagaag gggtatacaa acaaatatta gtatcggagt agagaaggtt gaacccaacc
      901 agtaaataag taaagacaat tttgtgctgc gttgagaagt gaaaaataaa cctttgtagt
      961 aatactagtt aataaaaaat atacaaaaac actgcgaaaa tcattcttga gtttcgcagt
     1021 gttttttgcc taatgactca agtttattgg gtaatacttt gattttcttt ctacaaataa
     1081 tcagcgatca gttgtaattt tttctctagt tttaatggct ctttgtcaat aaggagaaaa
     1141 acaagtcggg tcttttgtct cggaaagctt caaccaactc gtgaataaag gttacgcctc
     1201 cttgaaaggc gtggaaaaac caagtaatcg atcaatcacc aatttcgcat ttggtagaac
     1261 atgtttggtg agctgaaagt aggtggcgtt catgtctgta actaagaatt ctatttcttt
     1321 aggattagtg cagctaagga aatagtttgt taatcgagga attttttgtg taggtaaatt
     1381 ttctcgatta atttttctgt ctcgccatcc gcggaaataa aactcagttt atcctcaacg
     1441 gaaacgtgag aacgaaattc acaaccctca acactcaaga cagaattctt ttggaagact
     1501 ttggtaaata gcttctcaac tctttcaatg tgcgaataac ggttgtcaaa gatacctaac
     1561 aacttttcga aataaaaaat aacgacactt tttcagtcag taaagaagtg attttatgtc
     1621 tgacatgatt tgaaatcgag tgccttggac ggataaaata actttgagcg ttccaatggc
     1681 ttcgacagtt tttacaggta tagcgctgct tttttaggcg tataaccatt ggcatatgat
     1741 tatattattc aaagtggaca atggtttcct tcttcttgtt tttcaccacc attaatttcc
     1801 tatttccatc taccacagca gaaccacaat ttctacagac acatggagca gggaagagaa
     1861 ctgcagcaac gatcaatgtt tttttcttct gtaaggtttc gtaagagacc tctgtaatca
     1921 tcaaattttt gtctattgat ctcagaattt ttttgataga accattcata aagcatatcg
     1981 ttctctcagt tgtttatttt gtggtgattt aatcatacaa gaaaacgata tgttttttta
     2041 taaaaacatg aataggaaaa atagttgaca agaaaatgac aacgccatat gatgttccat
     2101 agtatttaca acctgtcata gatgactgta aaaaataaaa gtaaaaagaa aggacgacaa
     2161 caggtggatt tttatcagtc tctacaacta gatccgttta ttttaaaaca aaaaatacga
     2221 gaagcagctt ctaaaaaaga aaagtgcatg tatatttgtt cattgttttt acgatcatta
     2281 ttcatcgtat tgtttgccat ttgttttatc attataatta caacattatt tgaatcgaag
     2341 cataaaccat acgctgtggt tttattctgt atgttgatga gtattcgttt tgttgacttt
     2401 ggttataaga tttcccattc gatcataggt ttagcaatcg tcatgttctc actattagta
     2461 gcaccgtatg tccagctgat caaatggtca gttatgggca tgttgattca ttttatttta
     2521 ctaagcagca tattaatggc aaccgctagt gatcccaaaa tggggaatgc ttctttgtac
     2581 ggcttttcat atctctttat tgtttattcg ttacctaaag attcgttgaa caagaatttc
     2641 tttacacaaa caagtagctt attatttttg tttttttgtt ggttttcagt tcttctttac
     2701 agaaaacatc gagaaaagaa caaagacaaa agcttgttta aagagatttt tttgaaaggc
     2761 atgtattcgc aggaaaaaat ttggatgctc atctatgcat ttggcattag tcttttgatc
     2821 gttgcaggag agtatgtccc ttttcagcga ttgatgtggg cagggtttgc attttcttct
     2881 attgtatcta gctatggatt gatgtcgatt ggtttcaaag aacgagcagt agaccgaatc
     2941 attggctcat tgattggatg tgttttattt attggtatca gccaatttat tccttttaac
     3001 tgggtcggta tattaggtgg tctagcttta ggtgtttgtt ctacctatag atataaaaca
     3061 gtttttaatt cttttggtgc tttggcaatc actgccagtt tattcggggt tccaggagca
     3121 gtaacgatcc gcatttttga gaatatcctt ggggtatgtt taggaatcat gtatattggg
     3181 gtgactgaaa tacttatccg aaaaataaga gaaaaacacg gtttgaatca ttagatgaga
     3241 tcgaataaaa aataaggaaa aagtgaagat acacatggat gataaattgc tatcattcca
     3301 tgtgtatctt tttacggtaa atcagtgaaa cgttcgactt tcatttttaa tttatacttt
     3361 ttacggagtt cgtttatttg agccatcatt tcggatttgt gatgcttttc gattgcttct
     3421 tcatctttcc aacggtcgat cagtaaaaga gattctggat cttctagtgg aaagtaatag
     3481 tcatatttct cgtttccttc ttctgcacga atcgctttga caatgtttct ttcgaccatt
     3541 tcttctgcaa attttctggc ttgtccattt gtacttgtat acaaaatatt cactgtgata
     3601 ctcactaaat cccctcctga aaaaattcta tcactagtat atcacggtgc cagaaattat
     3661 tattcaagat atgatacaca ttttttccgc aatgctacgg aaatatatat tttgaataga
     3721 aaacgcttac aagatatgct tggtttataa aaataaaagg agtgattgat ttatgaaaaa
     3781 agcattgatt atttgtgcgg caggaatgtc atcctcgatg atggcctcaa agacaacgga
     3841 tttctttaag caaaaaagag aagaggtact cgtagatgca gtttcagcta cagaaggcga
     3901 taatatgatt aagaatagtg attttgattt atttctgatc agcccgcaaa cgacgatgtt
     3961 tttggataaa ttcaaaaaat taggagaatc tgttggaaag cctgttgtta gtatcccttt
     4021 ccaagcgtat gtcccaatcc ctacaggcat ccagaagtta gcagaggtga tcgaagagaa
     4081 catatgatgg aataggagtg gatgataatg aaacagaagg aaaaattgct gttgagatat
     4141 ttgattgatc acaagaagga gtatgtcacc agtcaacgtt tagcttctga attgttatta
     4201 tctgatcgga caatccgtaa ttacttgcag cggatcaaag agttagtaga aaaaaacgga
     4261 ggtaagatca ttgctaaacc aggttatggc taccaactgc atattttaca aagactgaca
     4321 tttgacttgt ttttgagtcg gcaagaaata gtacctggat atgctagaga accgcaagga
     4381 ttttatgagt ccgaagatcg acaaaagtat atattgaacc aattgctttt ggaagatgcc
     4441 attcttttta tggatgattt ggcagaagag ctttatatca gtcgttccag tttgacaaag
     4501 gacatgcaag aaatcaagga gcgattgatt ccatattcac taaaaatcgt ttctaagcat
     4561 ggtcaaggga catggatcga aggggaagaa agaaatcgac ggcattttat catggatact
     4621 ttttttggaa accattatgg aaattcattg aaagaatatt tagggcaaag ccgttttttc
     4681 ccagacatca gttttgaaga gctagtcatt atcattctcg atgaaacaag agaagctaag
     4741 ttaaaagttt cggattttat catacagaat ctgactttac acttggcttt ggggatcaaa
     4801 cggctccgag aagggtttga aatcaaggaa ttaggcatcg aacaagaagt ttctaagcga
     4861 gtagagtatc aagtggcgca gcggatcgtt caacgtattg aggtaatcgc aggtgtatcg
     4921 tttcccgaag aagaaattgc ttatttgaca ttacatctca tggctaagtc gaatcacaaa
     4981 gaaaatcaaa atgatcagga actatcaaag gaattagcga aagttctgaa aagattgtct
     5041 caggaatttc atttttcatt agtagaggat ctccagcttt tcaatggact actcgatcat
     5101 ttgtcaccga tgatgattcg attgagccga ggtattcgca ttgagaaccc attgactgag
     5161 gagataaaga aagaaaatcc caaagtcttt gacgcagtaa aaaggcattt cagcaacatg
     5221 ccggctttga aaaactatac catcaatgaa gatgaatggg cctatttggc tttgcatctc
     5281 atggcggcat tggaaaaaga aagagctgcg cataaactac atgcattgat tatctgtgca
     5341 acgggttacg gcagtgccca actattaaag aatcgcgtag tcagtgaatt cggtaaaaat
     5401 attacagtgg taagtgtaaa aggctattat gagatcaatg aaacaacttt aaaaggaatc
     5461 gacctgatta tttcttctat tgatctttcg acaatgtttt tcaaaattcc agttttacat
     5521 gtcagtattt ttttgaatga agatgatgtt cgtaaaatac gaaaggtagt tggagaatct
     5581 ataccctatc attcctcaga tagaccgata ccagcatttt ctctacagca aaaaaagcag
     5641 atttacaccg aacagttgtc tgaaaaattt ttcaagactt atacgtacga accgaaaaag
     5701 gaagaaattc ttcatgattt gctgcaaaag ctgagcataa atgaagaaga aggatatata
     5761 agagaaatgc gaaagcagat ccagcaacgt gaaaatatgg gacaaatcat attcagtgat
     5821 acagtggcag tcccacatcc cgctgttcca gttggaatcg aaacaaaggt agccgttgca
     5881 ttgattcctt ctgggatgca gtgggatcaa tatcaagaaa ttcattttgt ttttttagtt
     5941 tcgccttctt atgtcgaaaa tgaaggaatt acggtcgtga ctaaagcaat cgttaggtta
     6001 gttgaccagc taaaagtaca gcaggaaatc ttagctgaac ctatttttga gaatttcagc
     6061 agtaaattta tcaaactgat cgaataagga ggaaaacaga tggctgaaaa aataaacagt
     6121 gaaacactac aagtgacttc ttttgatatc attttccata gcggaaatgc acggacactg
     6181 atacatgaag catttcgctc gatgcgtaaa gagatgtttg aagaagtaga agagaagttg
     6241 cgacaagcaa atgaagagat tcttcatgcg catcagtcac aaactcaact tctgaaagaa
     6301 tatgccagcg ggacaaaaat agaaatggaa attatcatgg tccatgcaca agatcatctg
     6361 atgacgacga tgacattatt ggaagttgca caggaaatga attatttgta tcaaaaaaat
     6421 aaatagaaag gaaggatcat tgtgcaggat acagtaaaaa ggaaaatcga attagaaaaa
     6481 aagcaactta gtttgaaaaa catgtatttc aatcgttatc taatcgtacg ttacctgact
     6541 gcctttttct ttttcatgaa catgcaatgg atgattctgc ttctatcagc taaaagttta
     6601 ggaagtagtt taccgatgat tctgatttta gctattttgc ctgcagtagg agaacaagta
     6661 aagctttatc gaaaacacca aacgaacgtt ccatggacaa agtggtattt tttgttccag
     6721 agtgtcttta atttattagt gattccagtg ttgtttacct caggatttac attcttgtat
     6781 ccttttatgg caaataacaa tggaggacag ttatttgttt tcattcttgt tgtaagcggt
     6841 atttttgcca gtgcatttat acagtatcgt ttaaagaaaa tttcactcaa ccaagaccaa
     6901 cagtatatcc gtattaaaca atatgaaaaa gcgttatatt taggaaagga gaataactaa
     6961 tgtttgattt tttgcagaaa tacctgatgg gacctatggg gaaaattgcg caacttaaaa
     7021 tcgttcgggc tgtcatggca gcggggatgg cttctattcc tttcacgatt gtaggctcga
     7081 tgtttttggt tttaaatatt ttgccattac cgttcccatt tttagaagga ttttttaatg
     7141 caactttttt caaagttagt gacttgtaca tgatcgtcaa tacaatgacg atggggattt
     7201 tatctattta ctttgccatt gtgtttgctt atgaattaac gtcaattgaa cgagatgaac
     7261 aaaaattaaa tgttaatccg ctcacggggg cattactatc tgtttttgca ttctttatgt
     7321 gtatccctga attgatcatg actgatggta aaatcagctt gattgcttct atcaatgaga
     7381 cagaaactgt agtaaatggt attaggatgg gctcttttgt cgaacgttta ggaacttcag
     7441 gaatctttac agctattatt atgtcgatta ttgcggtcga attgtattgt atgtgtgtca
     7501 agagaaattg ggtcataaaa atgccagatg ttgttccgcc aggagtttct cgttctttca
     7561 ctgctctgat cccaacattt gtcattgcgt ttgtggtgat gatcatcaat ggattattag
     7621 ttgcactagg aacggatatc ttcaaaatga ttgctatccc atttgggttt gttacgcagt
     7681 tgacgaatac atggcttggt gtcatggtga tttatttctt gatccatgca ttgtggatcg
     7741 tagggatcca tggagcgaat atcatcactt ctttcttgac cccgatcgta ttagctaata
     7801 tggcagctaa cgcacaaggc gcaaattatc cgttggcagg agaattcaac aattcttatg
     7861 taaccgttgg tggatcaggt gcgactttag gattgatcat ctttattgca ttcctcgcga
     7921 aatctgatca gctgaaagtg ttaggaaaag cctcacttgt accaggatta ttcaatatca
     7981 atgaaccaat cattttcggg atgccaatcg tctacaatcc ctatttagcg gttccgtttt
     8041 tcttagctcc gatggcttct gctacactcg cttattttgc cattcggctg gaaatcgtca
     8101 aaccgatgct tgcacagatg ccgtggcctt caccagtcgg gatcggagca tttgttggta
     8161 gtggtggtga ttggaaagct gctgtgttag cagtcatttg tgcaatcatc gcattcatta
     8221 tctggttccc atttatcaaa ttctatgata ataaattatt aaatgaagaa agagaaaagg
     8281 cagcagaatt agctagtgaa aagttaaaat gatttctaag aaaaaaggaa ctgtgacaaa
     8341 aaatcacagt cccttttttt cttagaaatg ggaaaccact agtatataaa taccattatt
     8401 cttcaatcaa ccgcttcacg attgcataat ccccttcata aggttcatct acaccattga
     8461 ttttttgata gggatccacg ccttttcccg caataacgac tgaatcttgc ggagcgcttt
     8521 ctgctaaagc gcgtcgaatc gcttcaggac gatccatttc ataatgaacg atcaaatctg
     8581 gattagtaat tgcttcattg atttcttccg cgattttttt cggatcttca aatgctgggt
     8641 catctgccgt caaaaaggcg atgtcagctg tttctgatag cacttttcca aaatcatgtc
     8701 gacgggagat tgctttgttt cctgggctgc ctaatacaac aattacacgg ccatctggat
     8761 gttcattttt ggcaaattcc agcaatgttt tcaagcttag ataattatgt gcatagtcca
     8821 catagacatg cgctccattg gattggatca attgatccat tcggcctggt acacgagctt
     8881 cttttaatcc gtcttgtgca tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg
     8941 cactggctgc attttcttgg ttgaatcctc cagccagcaa aatatcataa gcagtatcgc
     9001 agatagctaa gcgatcttca tgagaagata aagtaaaacc gtgagtacct ttatctgaac
     9061 ggatcacttg ataattgctt tcttccgaac gaccataagt gatcgttgga atctggaata
     9121 gatcggctgt ttccctaagt aaatcaaaat agtcactttc atgatttaaa acaactgttt
     9181 ttgaattcaa gatcaattgt cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga
     9241 tcggactgat atggtcaggc gagatattca agaagattcc gacatctaaa gtcaagccgt
     9301 atacgcgttg tgttttgtaa gcttgtgaag aaacttccat cactagatga gtcataccat
     9361 tttcaactgc ttctgacatc atacgatata aatctaatga ctcaggcgtt gtcaaatggg
     9421 atttgaaata tgttttgcca tctaacgttg tattcatagt agaaagcaat gctgtttttt
     9481 tatttgttgt gtgatccaag attgcttttg taaagtacgc agcagttgtt ttaccttttg
     9541 ttccagtgaa tccgatcact ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa
     9601 gaagcgccat tgctttacgg atatccgtta cgatgattcc tactgctgaa ttttcgtatg
     9661 gttgttctga tacataatat tgaataccct gttcgattgc tgaatccaaa tattcttctt
     9721 tgaaattcat tcctttacag aaaaacaaag tagaagcatc agcttttctt gaatcataac
     9781 ttaactgaag aaattcagct ttttctggta catcaagatg ccagcctctt gttgaaacaa
     9841 attcttttaa tagattttct tttaatagta aatgacggat gtcttctaaa gagaagctca
     9901 ttgattgatc cctcgcttta ttcaatttct tggtttatta tagcacactc tttttaatat
     9961 atcgtttgtt tccgctatga caaaatccag ctttattcaa attttcttga cacaggggac
    10021 aagcggatga gtattttcat aaacaatgaa ctgactgtaa tagataggag aacgaatagt
    10081 gtctccaaca atccaaaaac ataataattc aaaaagacga taagactatt ggtaagtaaa
    10141 agtccttgcg gcattggaag ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata
    10201 ccgccatttg aggccccgac tgtgtacaat gtgtaaaccc caagactgaa caaaagactt
    10261 cctgaaatca gtgaaaagaa atgtgaggag atcatttcca cttttggaac aatctctaaa
    10321 acaacaggaa aaagcagact tcccgctaca gtcttaaaaa atactgattt tcctaatagg
    10381 acagcggcta gaagcagcat cataagattg atgctccaaa cagtaactga gcgttggata
    10441 gaaaaggccg tttcaactaa atgtccgatg gcgcccactc cggcggaagc tatatcgtga
    10501 gggagcaaga accaattcaa tccaactgtg ataaagaaaa gacctaaaaa tataacgggt
    10561 agttttttta tttcttgtgt cattgatatc tcctataaat gttagccata aaaggctgta
    10621 tatttcttta ctttaccaaa aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa
    10681 agttatataa aatcgattgc cagtttctgt tttaccaatt aaaatgatag taatgttttg
    10741 tagaaagttg gaatctgacc gatggataat caaagaaaac cagcattaga tcaattaaca
    10801 ccgcaagaaa aaatggcacg aggctctgct tggatgaccg ccagtaatat catttcaaga
    10861 ttgctaggcg ctgtctatat cattccctgg tatgcttgga tgggcgaaaa tgctaaggct
    10921 gccaatggat tattcaatat gggatacaat atatatgcat tgtttctact gatctctaca
    10981 gcaggaatac ctgctgcgat tgcaaaacaa actgcacgct ataattcatt gaatgaatat
    11041 ggcacttcac gacgattatt tatccgtgca ttacagatga tgggcgggct aggcctgttg
    11101 tttgctttgt tcatgtacat cgcctctcct tggctagctc atgcttctgg tggcggagaa
    11161 gaactgattc caacgatgcg ttctttgagt atcgctgtat tggtttttcc ttgtatgagt
    11221 gtgatacgag ggtattttca aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt
    11281 gtagaacagg tggcacgtat tttttatatg ctattggcta cattcatcat catgaaagtc
    11341 atggatggtg actatgtgac ggcggtcacg caatcaactt tcgcggcatt tatcggtatg
    11401 ctagcaagta ttcttgtcct tttgtatttt ttgaagaaac atcaagcgta tacatcggcg
    11461 tttattcact acagcgaaaa caaaataaat attgcaacga aggaattgtt gttagatacc
    11521 gttaaagaag cgattccgtt tattattgtg ggttcagggg taacgatctt caaattagtc
    11581 gatcagttca cttttatgaa gatcatgtct gcatccaccg agtattccaa tgcacagtta
    11641 ctggatcttt tttcgatttt tagtgccaat ccagataagt tgacgatggt agttattgca
    11701 ttggcaacat cgatcgcgtc tactgggtta ccgttgatta cagaagctgt tacgttgaaa
    11761 gatcgagtag gtctggcaaa attgacaagc ggaaatttac agttgttttc attttttatg
    11821 tttccggcga catttggtgt tatgttactt gcctatccgc taaatacatt attttataca
    11881 ccggattctc taggaagtaa tgtactgatc caagcaagtt ttgtaggact cttcctagga
    11941 ctatatatgc tagtttccaa catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat
    12001 tatttggtta ttgggtttct agtgaaactc cttcttcaat acccagccat tcgtttattt
    12061 gaagtatacg gccctttatt ggcgacaatg atcggatttg ctgtgtcttg taccttgatc
    12121 ttaaagagaa tccatgaagt agcccgcttt aaaccaagtt ttgtctggcg caggacattg
    12181 ctgatcttta ttcttacctt gattatgctt ttggcttcgt ggatcacaaa gatgattttt
    12241 ggtgcttttt taaacgaaga tagcaaattc cagtctctat tgttgattct tgtagtagca
    12301 ggtatagggg ctttagtgta tggttattta gctttgaaaa tccgcttggc agaaagacta
    12361 ctaggaccag gaatagcgcg tttacgacat aaattaaaaa taaaataagt gaatcagaag
    12421 agctagattg atgctctttt gaaatggggg aaacgcatgc gtttagataa gtttttagca
    12481 gatatgggac ttggcagccg caaagaagtc aaaggattga tcaaaaaagg aacgatcgaa
    12541 gtcaatggac aagtggtgaa aagcgataaa gcgcaagtaa atgaattcga agatgcggtt
    12601 acttatttag gagaaatcat tacgtatcaa aaagattttt actacatttt gcataaacct
    12661 gcaggagtca tttctgctac tcaggataat catgatcaaa ccgtaatcga tttattggaa
    12721 gaccaggatt atcgggaaga tctttttcca gtcggccgat tagataaaga cacagagggc
    12781 ctcttgattt taacgaatga cggggtgttt gcccatcagt tactatcacc taaaaaacat
    12841 gtggagaaag aatatctagc tgaggttagc ggtataatga cagaagaaga tatccgttta
    12901 tttgcagaag gactgattat tgatggcgat gagcagacat tgccggcaaa actccaaatt
    12961 gatcaagtag atcaagagac agaaacttca attatccgtc tgattttgca tgaaggaaag
    13021 tttcaccaag ttaagcgaat ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga
    13081 atccgtatgg gaaaattttg gctgcctaaa gatttgaata aagggcaata tcgacccatg
    13141 accaaagaag agctagaaca agtgagagaa aaataattga atggatagct aaaagaataa
    13201 gcagagtagt tgtagcgcca tctgaaaagc agacttgtcc gtctgacttt cggatggctt
    13261 ttttgtgaaa tttcggctta tttccgtaga agctacttct ggaacaccgt ttgttcggaa
    13321 taagggactg tgacaagact tttgttacag tccccattgt tccttgtgac tcagagttag
    13381 atagtaagga cacgatctcc ctaatactca ggccaaaacg ctgaattcac aacctctgat
    13441 aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa atatgaggaa
    13501 ctattttccc gtttttttct ctaatactca ggccaaaacg ctgatttcac aacctctcct
    13561 atactttgtt tcattttccc tatactttgt ttatttattc tcattattga aagcgctata
    13621 attacgttgc gaatgaatcg aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca
    13681 tttttttatg aatctatggc gttataaagc acttgtcctg atggctgtac cgggtatgct
    13741 ttggatgatt tttttctttt acatacctgt aatggcgaat gtcgtagcat tcaaaaattt
    13801 tcatatttca gcagatgggt tcttggctag cttgagggaa agtccttggg tgggttggga
    13861 aaatttcaaa tttttatttt cttcggatca agcatttctc atcactaaaa atacaatttt
    13921 atataatgta gcatttatcc ttttgaatct gctgatctca gtcgtatttg caatcattat
    13981 gagcgagttg agaaataaac gactcgttaa agtttatcaa acgatgtcct tactacctta
    14041 ttttctatct tgggtcatta tcagttactt tgtttacgct tttttaagtc ctgacaaagg
    14101 aatattcaat cagtggatca ctggacatgg aggagaagct gtcaattggt ataatgaacc
    14161 gaaatattgg ccgtttatct tggtgttcat tggtacatgg aaagggattg gttataacag
    14221 cattatttac tttgcatctg ttatgggaat cgatccgact tattatgaag ctgctatggt
    14281 tgatggagct agcaaatggc agcagatcaa acatgtgacg ataccacaac ttattccact
    14341 aatgacgatt ttaacgattt tagccgtagg aaacattttc cgagctgatt ttggcctgtt
    14401 ttataacatt cctaggaatt ccggtgcatt atatgatgtg actcaagttt tggatacgta
    14461 tatctacaat ggcctgacat ccacaggaga ttttggtatg acggctgctg caggacttta
    14521 ccaatcagtt gtcggctttg tcttgttgat gatcacaaat acgatcgccc gacgttttga
    14581 tagcgattct gcattattct aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc
    14641 caagtccgct ctttcaataa gacggctaat tttttctcta atataatgat tgcactcttt
    14701 gctatttcct gtattttgcc atttatattt gttatcgcca tctcttttac cgatgagtcc
    14761 atattgtcga ctcacgggta cagtttttgg ccagaaaagt tcagtatatt tggttatacg
    14821 tacttgttcg accagatgca ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt
    14881 actgttttag gtacactgat caatagcacg gctacttctt tatatgctta tgcgatttca
    14941 cggtcaaact ttccattccg tcgttttttt accgtttttt gtttgattac gatgttgttc
    15001 tcaccaggga tggtggccaa ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg
    15061 atttgggcat tgatcttgcc aatggctgtc agtcccttca atattattgt gatgcgcaca
    15121 ttctttaaac gttcggtctc tgattcgatt attgaatcgg cacggatcga tggagctagc
    15181 gaactgcgaa tatttgttca gatcgtttta ccgttagctg ttccaggtat tgcgacaatc
    15241 agtttatttg ccgcattggg ttactggaat gactggttca atgctttact ctacatccaa
    15301 gatgataagc tagttccact acagtatctt ttgatgaaaa tccaaagtaa tattcaatat
    15361 ctgacacaaa attcaggagc aggaagccaa ttgacaggcg gattagcctc agttccagga
    15421 gaatctgcca gaatggcgat cgtagtcatc tcgacgttgc ctattgcgat cagctatcca
    15481 tttttccaga agcattttgt caaaggtcta acaatcggcg gagtaaaaga ataaagaaac
    15541 aaaaatataa atcataaaat taggaggaag aaaaatgaag ttatggaaga aactagcctt
    15601 tacaggtgtt tcagcgttgt tgttgggaac attagcagca tgcggaggtt ctggttctaa
    15661 agaccaggca gaagctagca attcggacac tttgcagatg tatcaaatcg gagataaacc
    15721 agataatttc gatcaattga tggaagtagc aaacaaacga atcgaaaaag agatcggtgt
    15781 aaaagtcaat atcaattaca ttggctgggg cgattacgaa aagaaaatga acgtcatcat
    15841 ttcttccggg gaaaattatg atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa
    15901 aggagccttt gctgatttga ctgaattagc gcctaagtac gctgaaaaag cttataatga
    15961 tttagatgaa gcatatatta aaggaaatct ggtcaatgga aaattatatg ctttcccagt
    16021 caatggaaat gtctttgctc aacaagtact tacttttaac aaagctttac tagataaata
    16081 cgatctttca attgatggaa tccaatctta cgctgatgca gaaaaagtct tgaaggaatt
    16141 ccatgaaaaa gaaccaaaca cggcagcttt tgccattgga caaggcttca aagtccaagg
    16201 gaactttgat tatcctttag ggaatacgtt accatttgct attgatctgg atggagatga
    16261 ttcgaaaatc atcaaccaat acgataatga aacgtatatc ggactgttac gtacaatgca
    16321 tagctggtac aaacaaggac tcattccaag tgacgctgca acgagcaata aggattatcc
    16381 actagaagga aatacttggc taatgcgtgg agaaacacaa ggaccgtatg attatggcga
    16441 tacaattttg acaaatgcag caaaacaaga acttgtctca aaagcaatta ctgttccact
    16501 aaaatctaca gctcaagcac aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa
    16561 agaaaaatca gtagaacttc tagggctgct taacagtgat ccagaattat tgaatgggct
    16621 tgtttggggg atcgagggag aagcatggga aaaagtcgat ggttcagatg ataaaatcaa
    16681 attgctagat ggttatcagc caaatacaca tatgtctgct tggaatacag gaaacaacaa
    16741 gattctatat acacaagagt ctattacgga tgacatgatt gccaaacgtg atcaatcgat
    16801 tgctgatgca gaaacttcac cgattttagg attcagcttc aacactgaca gtgtcaaaac
    16861 agaattaagt aatatttcta atgtcatgaa tcaatattta gatggattga atacagggac
    16921 tgttgatcca gatgaaacat taccgaaatt gaaagacgct ttggacaagg ctggctatga
    16981 taaggtattg aaagaaatgc aaaaacaata tgatgagttc cgacaagaat aataatgaat
    17041 aaagacaaag gggttgtgac aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt
    17101 tcaaaagcca gtttctcggt attaagctaa atatatgtaa aaatgtggaa agccatattc
    17161 acaaaatttt tcttactact cgaaactaag cggctatttc acaaactctt ggtaaacggt
    17221 gttcaatcag ctgaccctcg gtattcgctc acaaaacgac aaaatatgag gaactatttt
    17281 tccgtttgtt tctctaataa tcaggtcaag gtgctgattg cccaaccttt ttttgtataa
    17341 tgagaaagta taaacttaat gtttggagga gaagatatgt tagggaaggt tttggaagag
    17401 ttatttatcc ggatctgggt cattataaaa ctaaccttgt atttctggat atatacattt
    17461 gccggcggga tcatctttgg attaggtgcg gcatggaaaa cagtcaatga actattttat
    17521 ttgtacggat tcgagtataa agaaatcaca ataaaaagag gctggaatat atataaaaga
    17581 aattttttaa gaggcaatct gctatttagt ttatttttat ctggtactgc tttattgagt
    17641 tacaatttat atttatctgt tcaaatcaaa gggctcattt ttttagctat tgattttatt
    17701 ttactttttg ccttgctctg cctatttgct acttatcaat acagtatgat tttagatagt
    17761 gaatatacga tctctgttcc taatctgcta aagctaagtt ttatttcggt tttttccagc
    17821 ttttcgtctt ttctaaaaat aattattggt agcggtataa ttttaggcgt gacttggcaa
    17881 ttcaaaggat tgatcctgtt tggtgtcatt ggtcttttga cggtttggaa tggtacgatg
    17941 acaacacatt ggcgtgaaga attagataaa cagttggaaa gttatgaata agtttcggat
    18001 tctattttca aaaggaacct tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat
    18061 cggtgtaacg atgactgcta ccgttatttt tagtatccat acttgggaac aaaatcaaaa
    18121 acaggcagaa aacatgacaa gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa
    18181 aacaaccttg agtaggatca tcaaaaacca gcttgtaggg aattccgaaa agatcgaaaa
    18241 tgtgacgacc tacttaacaa aacccataga tcagtatctg atgtatgtat acgaacagca
    18301 aaacagtacc gatgaattag tttctttccc aaatcaaatc aaagatctct acgcaaatta
    18361 tgaagaacta agtgcgatat atatcgtgtt gaatcaacta ccggagtatt atgaatcttc
    18421 tagagaaaac aaaggtgggg aaataaaaaa ggggacacca aaattactag acgcctttta
    18481 tatcaagttg cctatcacac aaggaggagc tgagtcagga agtattttta ttggttttca
    18541 aaagaaagaa ctagatatga ttttagaaaa tctaacgtca ttcaatggac tctctttata
    18601 catgatttct ggaacgacaa atcgactata cacattccat gataataaaa tagctaaaga
    18661 aacgtttgaa agacaagaaa tgatcatcac agagagtctg aagaaaaatt cacaattgcc
    18721 gattgacgat ctggaaaaaa acaattttgt tcaacaccaa gaactgtctg atgattatcg
    18781 tatattagct gtactagata aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc
    18841 gctgatcatt ggtatcatta ttttagacaa tatactgctt atctttcttt ataaaacatt
    18901 caaacgatat tcacagcaag tatctatcgt catgcaggcc atggatcaaa cagcagcagg
    18961 gaatttagag acgcggatcg acataacaaa cacggaatat gaactgaagg aactttcaat
    19021 cggtatcaac gaaatgttgg atagcatcaa tcagtttgta gaagacatct acaaattaga
    19081 aatcaaacag caagacgcac atatgcgggc gcttcaagca cagatcaatc cacacttttt
    19141 atataataca ttagaatata tccgaatgta tgcaatcagc gaaggaagtg aagaattagc
    19201 agatgttgtg tatgcgtttt ccgctttgct tcgaaacaat acgaatcaag agaaaacgat
    19261 cactttaaaa gaagaactgg acttttgcga aaaatatgtc tatttgtatc aaatgcgtta
    19321 tcctaatcga gtagcctatc attttatgat cgatcctgat ttggaaaaga tcgaagtacc
    19381 taaatttgtg atccagccat tagttgaaaa ttattttaaa cacggtattg attttactcg
    19441 attcgataat gcgctaagtg tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat
    19501 caaagataat ggaaaaggga tgactgaaaa acggctaaaa cagattgaag aaaaactgtc
    19561 tcatcctaaa gtggaacttc acggttctat cggtctgcaa aacgtgaatg aacgtttacg
    19621 tgccagcttc ggcagcagtt attatatgtc gcttgagaat aatgagacag gtggactgac
    19681 cgtttctatt acattcaagg agggatgagc gtgtatcaag tgttattggt agatgatgaa
    19741 tacatgattt tgaatgggtt aaaaaagata attgattggc aaagtttagg ctttcaaata
    19801 gtagcaacag cagagaatgc caaagaagga ctagctgtac ttgaacagcg acagattgat
    19861 ttagtagtaa cggatgtgac aatgccagaa ataaatggac tggaatttat tgaagcggct
    19921 caaaaagaac gtcataattt tgaatttatg attttatcag gataccaaga attcgattat
    19981 ttgaaaggag gtatgcaatt aggcgccgtg aattatttga tgaaacccgt gaataagttc
    20041 gaattggttg aaagcctcaa gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa
    20101 aatcaacaag aaatctatca agaactgtta ttcagtcaat ggttgaatga agaattggat
    20161 gaaataagtg aagaagaaat aataggacaa ataagtgaga agcagcatag gatagtattg
    20221 attcaactgg caagaactca tgatactctt atcaatagat ggttgcaaga acggcaacaa
    20281 atcttttact atcaacgaaa ttacggagac cgtgtattga tcacgttgtt gttggaggca
    20341 gatgaagttg atggcttctg ttgttttgtt caagaaaact ttcctgatca ggaatggctg
    20401 atcagtatcg gggaagagac agattctttg gacaaaatcc ctgaaacatt ccaacaagcg
    20461 aaagacaatc tacagttgca tcaattttat ggagataaag acgagcatgt tttttacgca
    20521 gtacaagcag aaacaaaaga tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa
    20581 aataaacaat tggaagtcgc tcaaaaaatg atcactgatt tttttgaaca gtttcagtta
    20641 gcagccatga tgccggaaga tatacgatat tccagttttt tactgtttat ggagattcaa
    20701 cgggaattga ttgatctgga agatgaggaa tatttacaag gaatcgaaaa aatccatcag
    20761 gcaaaaacgg tgcaagaact tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga
    20821 cagaaaaagt acagtgacaa tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa
    20881 gaaccactta cactcaaaga agtgtcagaa aacctgcatt taaatgtcat gtatctagga
    20941 cagctgttca aaaaagaaac gaaaaaaagt ttttcagctt atttgaacca tttacgtatg
    21001 gaaaaagcga aacaactgct tttgcacagt aatcaaaaca tcaatgagat agcaagtgag
    21061 attggctaca acaacaccac gtatttctct aaattattca agaaaatcgt cggcagatcc
    21121 cctaaagagt accgagaaaa cagtggagaa tcataaaaaa aaaagccaat gtaatgaaat
    21181 aacttataaa aaattgtcta gaaatctaat tttgggctgt tcttattact tgaggcaagg
    21241 cagctttttc atgacctctc gataaacgga gttcaaaagc cagtttctcg gtattaagcc
    21301 aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttaata ctcgaaacta
    21361 aacagctttt tcacgacctc tccactaaat ggtgttcaat cagctgaccc tcggtattag
    21421 ctcaaaaaat ggcaaaatat gaggaactat tttgccattt gtctctctaa tactcaggtc
    21481 agaacgctga tttcacaacc tctcaataaa cggtgttcaa aagcttgcat ctgcggtaat
    21541 aagaccaacc aaacgaaaaa tatgaggatc tatttttgct tggctgttct tattacttga
    21601 tgcaggacag ctttttcaca acctcttgtt aattatagtt tgataaggaa aaaggcaaat
    21661 cttttgcttg atatttctta gggtgaggga tgatccctaa ttggtaagag atcgtgccgc
    21721 ctttcagcaa atcttgatgg gtaaaatata atttcgtata ttctctgtcc atccgtttga
    21781 ttttatggat aaattgttgc tgcggccgat taggcgttgc ttcaatcgtc aattcctttc
    21841 catttgacaa aagcaaaaca gccttgtcaa ttaatggcat accgataaca tattcaccgg
    21901 ttccaggcgt gacaggataa aatcccagac tattgaagat ataccaagcg gccatacttc
    21961 cattgtcctc atctccaggg taacccattg gagaatcgtc gaaggtctga gtcatcaact
    22021 gtttaagcag tggctgtgcc atttcaggtt gtcctatata actgaacaag taaggatagt
    22081 gaaaacttgg ctggtttgaa atagctaatt gtccaaattc tatcgcggcc atctcactca
    22141 tttcgtggat ctcaaaacca tatcctcctg ggtcaaacgt tgggggctga ttgcacagct
    22201 caatgagttt ttctttatat ctctcactgc caccatattt tccgatcagt cctgaaaaat
    22261 cgtgataaac agcaaagctg ctttgccaag cacttccttc tgcataatct tgtccccaac
    22321 gattagctga aaatggttct ctgaacttgc catctttatc ttttgaacgc ataaatcctg
    22381 actcatagtc aaagatattt tgatagttca atgattgctg ctgatatttc ttcgtcattt
    22441 cctcttcttc tagtaccttg gcaacttggc taatacaaaa atcgctataa gcatagtcta
    22501 atgtgtgatt gactgattcg tggtagtgat taggaacata gccatatgtc aagtaatctt
    22561 ctgttccttg gcgtccataa tttggatgtt tgctttgaac cgtagcacct ttttccattg
    22621 ccgttagaaa ttcaggcatc aagtctcgtc ggatatcttt tacagcagca tctgcaatga
    22681 ccgcatcgat caatgtccca ggcataagtc cacgttcatc aggagacagc cattttggca
    22741 aatagccact ttctctatag ctgttcaaaa aaccttccag catttcttcg tatttttcta
    22801 cagcaatcaa agaataaaga ggataaaccg ttttatacgt atcccaaaac ccattatttg
    22861 tatagagaac accaggtttt atagatcgac tagtcgtatc atagtggatt ttttgcccac
    22921 taggatcaat ttcataaaat gtttgtggaa ataaaaacac ccgatataaa ttatgataaa
    22981 acgtccgcaa ttgttgttga tcatggtgtg tgagctgtat acgatcaaaa taggactgcc
    23041 attgttcttg actgtgagca aggtaagtct ctttgctttg gttttgttct agttccaggt
    23101 tataagctgc ttgttccgag ctgataaaag atgtcccaaa tcggatagtt tgtttttttg
    23161 tctgttcaaa atacaacggg atcgagtcgc tatttttgtt ggaaacagct aactcatcaa
    23221 ttgttaaagg atattcaaat ctcaatataa aataaaaaga aaaatcagga tcttctgaac
    23281 cagcaaaatg tgtgattttt ccttccactg tgtaaggatc tataacaaag agctgatggc
    23341 gtcccggaaa ggataaaagt aaaccgctgt catttttgct gtaatcaata gataagattc
    23401 cgccatacat gctaggtatc aatgtagaac agatgccata acgtaattga cagatcgaca
    23461 gatgagtcgg gcaaaatata ctttcttctg ggcggtaaga actttgagca tggaaaaggg
    23521 tgttctcctg tagttttcca ttgatcggcg taaacagcat atgactgaaa tcacccatcc
    23581 aaggacttgg ttgatgggta agacggtagc cttgaaaaac gcggtcatca ggatgaaacc
    23641 accagctgcc gttttgatcc gtagtttgcg gtgcaaaata attcatccca aaaggaacgc
    23701 cagtataagg ctggcagttc ccattagaga aatttggctg attcgctgtt gcatgtctag
    23761 tatctatttg accgatattc attttatttc tcctttgttg attgtctttt gatgaatgaa
    23821 actggaaatt tactatcgga tggtcgatct tttgtctcta accaagtgac caaagcatct
    23881 cccgcaagct tacctaactg ttcaaaatct tgtgcgatgg ttgtcagtgg cgggtcaaca
    23941 agagctgctg cttggatatc atcaaatccg ataattgaaa aatcttcagg gatatgataa
    24001 ccatgctgtc tcaagagatt catggtctgg atagcgacaa catcgttttc acaaacaaaa
    24061 gcagttactt catacttagt gatataagaa agcaattcat ctaatgtcgc gcttttgtca
    24121 tccagtgaag tgtggaaagt caaaccagct ttgtccaatg cttcaaggta accaaggtaa
    24181 cgctgtcgaa cggattgtgg atgagtctgc gtaccaaaca aataagcgat ttttgaatgt
    24241 ccctgttcga tcaaataaga ggcagcaagc gcaccgcctt ggaaattatc ggaaagaacg
    24301 gtaggaaaag gtaactcata gattttttta tctaatatga cgacagggaa ttctttcaat
    24361 gaaagctcaa aaagtaagtc aagatgttgt tctgtatcaa gagcataata aatcaatccg
    24421 tcaaattcat tgattagctc ttttgctgtt ttattttgta gaaagtcaag cgtcgtcatc
    24481 atgacatcaa tctgtttatc ttgcatcaca gggttcaatc ccttgctaaa atcaccaaca
    24541 gacaaatcag cgacatatgg aagaagaaac agaatccgtc gtgtttttgt aggagaagca
    24601 agaatctgtt ccggagaagc ggatttaacg aaactgcctt tcccgcgaac gcgataaata
    24661 agtcctaatt gctctaattc agtcaatgca cgtttggaag tgattctgct tactttatag
    24721 gtacgtgaaa gttctttttc agttggtagt tggctgtcta caggtaattc accagttaaa
    24781 atagccgttt gcaaatcatt aaatattgtc tggtacaatg gttgagtcat ataaacacct
    24841 cttaatgata tatcatattc aaataatacc ataatggatg aaaaagtaaa taaaaagata
    24901 ttttttgaaa gcgtagacat aattggctgt atgaagtata atctttaaag atatatcaaa
    24961 tagaaagaag gttttattag tggtttataa agatatacca aaatcggtgc agaaatttat
    25021 ggaagatatc acacaaaaat gtggggatat ccatgcggac tgggcaaaga attttacagc
    25081 agcatttgcc aatactctgt tgacaacagt caaaaagcaa aatgacggaa ccaccttttt
    25141 attgacggga gacattccag cgatgtggtt aagagactct actgcacaag ttcgtcctta
    25201 tttagtgatt gcaaaagaag atgaggaatt agctgacatg atcagcgggt tagtcaaaaa
    25261 gcaatttttt tatatcaata tcgatccata tgcgaatgcc ttcaacgaag aagctaacgg
    25321 tgctggccac caaacagatc atacaaaaat gaacgattgg atctgggaaa gaaaatatga
    25381 aattgattct ttatgctacc caatacagtt ggcctatctt ctttacaaaa atacaggaaa
    25441 aactgatcaa ttcaatcaat cttttattga aggtatcaaa aaaatcttgg acgtgttcaa
    25501 aacagagcaa gatcatgaac actctcctta tacatttgta cgagacacga caagaaaaga
    25561 agatacgctg atcaatgacg ggcgaggtgc aaaaacagct tttacaggaa tgacatggtc
    25621 tggtttccgt cctagcgatg atgcttgccg ttatggatat ctggtaccat ccaatatgtt
    25681 tgcggtggtc gtgttaggtt atgtggaaga aatttttcaa acgatactcg atgataaaga
    25741 aattgtacag caaacacaga aattgaagaa agagatccaa gaggggattc agaatcacgg
    25801 acgaacggtt aatcaaaaag ggcaaacgat ttatgcatat gaagtagatg gaatgggaaa
    25861 cgccacagtc atggatgaca gtaatgtgcc caatctgatc gccgcacctt acttgggata
    25921 ttgttctgaa caagaggaag attatctgca aacaagaaga acattgttga gtaaagaaaa
    25981 tccatatttc tatgaaggaa agtacgcaaa aggaattgga tcctcccata cgccagaaaa
    26041 atacgtttgg ccgattgcat tagctatgga aggaatgaca acgtcagaca aatctgaaaa
    26101 agagcggata ttgaatttac ttgtagcaac tgacgcagga acacacctta tgcacgaagg
    26161 attcgatgtg aacaatcctg aaaattatac gagagaatgg ttttcttggg caaatatgat
    26221 gttttgcgaa ttagtcatgg attactttga tattagagta gaaaagtagg aggtatcgta
    26281 aatgaaaaag aaagtatata tcatttctca tagccactgg gatcgtgaat ggtacatggc
    26341 ttacgaacag catcacatgc gactgattga attgatagac gatctactag agctatttga
    26401 agttgatccg tccttcaaca gttttcattt ggatgggcaa acgattattt tagatgacta
    26461 tcttcaagta aggccagaaa aaagacaggc aatccaacaa gcaatcaatg aaggaaaatt
    26521 gagaattgga ccattttata tcttgcaaga tgattttctt atcagctcgg aatcgaacgt
    26581 gagaaatatg ctgattggca tggaagaaag ccgtaaatgg ggaacccctg tcatgttagg
    26641 ctattttccc gatacatttg gaaatatggg acagacgcct caattaatga aacaagctgg
    26701 tatttcagca gcagcgtttg gccgtggtgt aaaaccaatt ggctttgata atcaagtttt
    26761 ggaagcagaa aactattctt cccaatactc agagatgtgg tggaaaggcc ctgatcaaac
    26821 agcaatcttt ggtctgctat ttgccaattg gtatagcaac gggaatgaga ttccagtaga
    26881 aaaagaagca gctcttgcct tttggaagca aaaattagcg gatgcagaac aatatgcctc
    26941 tacgaaccac ttattgatga tgaatggtgt tgatcatcaa ccggtacaaa aagatatatc
    27001 aaaagcaatc catctcgcaa atgaactgtt tccagattac gagtttattc attctaattt
    27061 tactgactat ctggaagcag ttcaaaaaga tgtgccagaa gacttaggct cagtagaagg
    27121 agaattgaca agtcaagaaa cggatggctg gtatacttta gccaatacag catctgctcg
    27181 ggtttactta aaacaatgga ataccaaggt ccagcgacag ctagaaaata ttacagaacc
    27241 acttgcgacg atggcttatg aagttagtgg aaactatccc catgatcaat tagattatgc
    27301 ttggaagaca ttaatgcaaa atcatcctca cgacagtatt tgcggttgtt cagtcgattc
    27361 tgtccatcgg gaaatgatac ctcgttttga aaaagcagat gaagttggaa agtatcttgc
    27421 acaagattcc ttagaacagc tgaccgcagc aatcgatacg accggattcc caaaagacag
    27481 ctttccattt gtcattgtaa atactgcagg aatggataaa actggtgaag cagaaataac
    27541 catcgaatta gaaagaaaaa gattcgctga aggaatacct gaacaactat atcaagagtt
    27601 agaaaatttg cctaaacgta agtatcatgt agaaacaaaa agtggggcca ctataccagc
    27661 tattttatct gaagaaactg tccaatttgg ttatgatttg ccgaaagacc gtttccgtgt
    27721 gccatatatg gcaagaatga tcaaagtgac tttaccatta gaaaacatgc cagcattttc
    27781 ttgggaaaca ttcgcgcttg tagaagggga agcgaaagca gaagaaaagg aaacaatgat
    27841 tcatcagagt ggacgaatca tcgaaaacgg ccctctacat ttgacgattg aaaaaaatgg
    27901 taccattaca atggaagatc gcaaaaacaa acgaaagttg aataatctgc atatttttga
    27961 agatatcggc gatataggaa atgagtatat ctttaaacaa cctttctgtg atcagccaat
    28021 cctatccagt aacaaagaaa actctgaagt aaaagtatta gtagatacac cggaaatagc
    28081 aaaaataagt attctacagg aaatggaaat ccctgtttct gcagacgagc gtttagaaaa
    28141 agaacagcag atggttgtgg aatttcgtta tcgaaaagca gaacgatcca aagaaaaacg
    28201 aatccttcaa ataaaaacaa tcatgacaat cagaaaagat agtaaaaaaa tcgactttga
    28261 aacgactctc gacaatcaga tgaaagatca tcgcttacgt gtcttgtttc ctacaaagtt
    28321 acatgtggaa catcacgaag cagatagtat ttttgaagtg gtgaagcgcc caaaccatgt
    28381 gtctaaaagt tgggaaaacc ccacgaatcc gcaacatcag caagcatttg tcaatattca
    28441 tgatgaagag tacggtgtaa cagtcggaaa ctttggtttg aatgaatatg aagtaacaga
    28501 agacggacaa atcgcagtga cgctacttcg cagtgtggga gaactaggcg attggggata
    28561 ttttccaaca ccagaagcac agtgtctagg tgagcatcgg ttcaattaca gcattgaact
    28621 acatggacca gaagaaaaat tctctactta tttgcatgca tacgcagcac agattccttt
    28681 ttccactcaa caaatcaaac atcatgaagg aacattgatt tcaaaacaac aatatttaac
    28741 gataaaaagt gaaacgtttg caattacagc tttgaaacgc agcaagttta gtgataaagt
    28801 agtagtaaga ggtttcaata tgtctagtca tttagaaaaa ttggaaataa ctaaagacaa
    28861 tggaaaaact gtcatattga atctgcttga agaaccaacg aagcaagcgg ttgtcccaat
    28921 aatccaacct tatgagattc ggacaatcgg attcgaggag gaaaacgaat gtatggcgga
    28981 atagaagcag gcggaacaaa atttgtgtgt gcggtttcag atggtggaga aattttagaa
    29041 aaattaagta tccctaccac aacaccagaa gaaacattgg atcaggtatt tgaatttttt
    29101 gatcgttatg aattgaaggg aatcgggatt ggctcattcg gcccgattgg tatcgacaaa
    29161 acaaaagata attacggata cgttttggca actcccaaaa aagggtgggc acaattcgat
    29221 tttcttggca caatcaagga acgctacaat attcctgctg cttggacaac ggatgtcaat
    29281 gctgctgcat atggggaatt gaagcaagga gcagcacaag gaaaaaatag ttgtatttac
    29341 cttaccgtgg gaacaggaat cggtgcaggt gtcgtgatca atgaagaaat tttttcaggg
    29401 atcgcacatc ctgaaatggg acatatttgg gtgaaacgcc atccagatga ccattatgaa
    29461 ggtacttgtc cttatcataa agattgttta gaaggattag cagcaggacc gtctattgag
    29521 gcacgcacag ggatcaaagg gcaagatctg ccgcaagatc atcctgtttg ggctattcag
    29581 gcttattata ttgctcaagc actgatcaac tatacgttga cgttagcacc tgaaaagatt
    29641 attttaggcg gtggggtaat gaatcaggat catctccttc aaaaaatccg tcagcaattt
    29701 gttgaattga tgggtggtta tatggaaaca cctcaagtaa gtgaatatat cgttcgttgg
    29761 ggactgccga atgaaagtgg gattatcggt agtttgctgt tagcagaaca cgaacatcaa
    29821 aagtaagcag acaaattaca caaaaagaac agagtcttat cattatctgc tgataagact
    29881 ctgttctttt ttatttctat tcccataatc caggtaaagc tttaccgact attttttctt
    29941 gagtaaatgg atggatcatg tgcagttcta atgcatggag catcagtcgt tcagctgttc
    30001 tattttggta gagagggtct ccaacgatcg gatgtccctt atgagctaaa tgaactctga
    30061 tctggtgtgt acgtccggtt tccaaaacac aatagacttg tgtttgttca gaaagtactt
    30121 tgttgacagt gacatgtgtc aaggcgctct gaccattttt atcatctacg accctttttc
    30181 tccgatcatg gcgatctcgt ccaattttat tggtgatggt catatctttg gcaatttctc
    30241 cccatacgat ggcttgatat ctccgataga tcattttttg ttccaacatt cttccaagta
    30301 tcggcaagac aaatggattt tttgcaaata aaacggcacc gcttgtttct ttgtccaagc
    30361 ggtggacaac gtaaggtcgt tgctgtttag tgtcgagata agcagctaaa tgattgagta
    30421 aggtactgtt ttctgtcggt tcatttggat gagtcttcat tcctgcaggc ttatccacta
    30481 taatcaaatg ctcatcttca tataaaacac ggatgtgctt cgcatctcct aattgaactt
    30541 cttgataatt ataatctgtt tcttcgaata acaatgtgat ctggtcattg ccctttactt
    30601 catgatggaa caaagcaggt tgttgattga tccaaacgtt tttacgtata cgcaaaaagt
    30661 gtcgaacctt tctaggaact aaccattcct tttcaagcaa gtcgcgaatt gttgtttcag
    30721 gatggttcat aggtaaagtg atcgtgattt tcacaagtgt actcctttca gtgcaattgc
    30781 agactaattg taccattttt aaaacatatt taagaaaaaa cttacatttt tctgttcatt
    30841 cttatgttac tctacttgca ctaacgtaaa aaaacatatt gaactacaac ttaagcagga
    30901 agaaaacact ctttcactat ggtaaaataa gacgattgaa tcaaatagac aggagaagaa
    30961 gcaaatggat tttcaaagca ttttagaaaa gataaaagct gctttgatca gtttttggcg
    31021 ttggatcaga ccatatctcg gacaattcca tcgatggcga aagcgcatct ggaaaaaata
    31081 tcatgtgaac aaattgattt tgctgattgg tttgatctgt gtcttagtga caagtatcta
    31141 cctctttatt ttagcaaaac aagcaaatgt cgaaacgtta aaatcaggat taagccaatc
    31201 gacagtcatt tatgataaga aaaacgaaga agctggcaca ctgtacgccc aaaaaggaac
    31261 atatgtagaa ttaaacgcga tttctcccta tatccaagat gcagtaatct cgacagaaga
    31321 taggaatttt tacgagcatc acgggtttga tatcaaaggg attgcccgtg cagcagtccg
    31381 aatggtcttg tctggcggaa catcaggggg cggaggaagt acgatcactc agcagcttgc
    31441 caaaaatgcg tatctgacat tagaccaaac gtttgatcga aaagcgaagg aattattttt
    31501 ggcaatcgag atcgaaaaga agtacagcaa agaagaaatc ttgaccatgt atcttaacaa
    31561 tgcctatttt ggcaacgggg tatggggtgt ccaagacgct tccagaaagt attttggagt
    31621 agatgcaacg aatgttacgc tgtctgaggc tgctactttg gcaggaatgc tgaaaggtcc
    31681 tggtatttat aatccgatcg atcacccaaa aaatgcgaat gatcggaaaa acacagtact
    31741 aagtgtaatg gaagaaaacg gaaaaatcac aaaagaacaa gaacaagcag aaagccagac
    31801 agatatcagc gcgtatctta atgacacata cgataattca gattctggtt atcgttatcc
    31861 ttattatttt gatgcagtga tcgatgaagc agttaacgag tatggtcttg atgaagaaga
    31921 tgtcatgaat aaaggctata aaatctatac agctttagat caggattatc aaaagcaatt
    31981 agaagctact tatcaaaaca gtgcattatt cccagcaaat gcttcagatg gtgccatggt
    32041 ccaatctgct tcagtagctt tagatccgaa tacaggtggt gtacaagcac tagtaggacg
    32101 aagaggagat catgtcttta gaggattcag ctttgctaca cagatgcgtc gttcaccagg
    32161 atcaacgatc aaaccattaa gcgtatatac accagcactg gaagctggat acaagccttc
    32221 cagtatcttg aaagacgaac cgcaaagtta ttacgatgcg cataattttg acgggacata
    32281 ccaaggagaa gtaccgatgt atcaagctgt tgcacaaagt ttgaatttgc ctgctgtatg
    32341 gcttttgcat gagatcggtt tacaaaaagg atatgataaa gcagaagaat tcggcctgcc
    32401 tttagcaaaa tctgataagt attatggctt agcccttggt ggactggaaa aaggagtatc
    32461 tccattgatc atggcgggtg cttacagtgc atttgccaat gatggtcaga tgtatacgcc
    32521 gcatcttatc acgaaaatcg ttgattcgac tggagcggtg atcgtcgata acacaaacaa
    32581 aaaaccaaaa caggtcatat caaaggaaac agccgatgaa atgaccagca tgcttcttgg
    32641 tacattttca aatggaacag cggctgctgc gaatcctgca ggttatacga tagcagggaa
    32701 aacaggaacc acagaaacta atttcgatgc cacaaaagca aatgaccaat ggatgatcgg
    32761 ttacacgcca gacgtagtga tttcgacatg gatgggttac gaagaatcca gcaagctgca
    32821 ctatttggaa gggacaagtg gaaatgttgt cgggaaagtc ttcaaatcag cggcagaagg
    32881 catccttccg tatacttcaa aaacaggatt tagtgtagca gatgcctatg ccacaggagg
    32941 acaagtggta gctgcagatc aagttggaaa cacaggaaat tctaatggag agtctggaaa
    33001 ttggcaagat aacttgaatc aatatggtga acaagcaaaa gaagggctga aaaacttcgg
    33061 cgatatggtg aaagaaggcg ttcagggaat tggtgaagcg gctaaagacc tctggcggaa
    33121 atatcaagga gagtagcccc tttgaaaacg aataacccca tgttacaata gagagtaact
    33181 actaaaagaa aagagggcat aacatgtcaa acatctacga tagcgcgaat caaatcgaac
    33241 gtgagatccg tgaattacca gaattcaaag cgttgaaaga agcgtacgag aaagtacaag
    33301 caaacgaaga agcacacaaa ctgttcaaag acttccaagc gatgcaaatc gaattacaag
    33361 aaaaacaaat gagtggacaa gagttcagcg acgaagatgc aatgaaagca caagaaatgg
    33421 ctgtgaaaat ccaatcagaa gaagtaatca atgacttgat gcaaaaagag caaggcttca
    33481 gtacaatcat caatgacttg aaccgtatca tcatgacacc agttcgcgac ctttacagcg
    33541 aataaaacta ttttatgaaa caacagaggg tgtgaaagag acgttcggcc ttgagcgatg
    33601 acaaaattgc ttcttattgc cgataggctg tctcttgaac accatttacc aagaggtcgt
    33661 gagcctaccg tttaactctg agttacaagg aacaatttca aaaaacagct tctcatgttt
    33721 gatgactatt gtgacttgtg accgaggagt tggcaggaga acaccgttta ttcagaaata
    33781 ggagctacga caaaagtctt gtcatagctc ctattttttg tcattcattt ttcaagcggt
    33841 agaaatagcc tttttgagct aacagttttt cgtaagtacc tatttcaacg atttttcctt
    33901 catcgatcac aacgatttta tctgcctctt tgatcgttga aagccgatga gccacaataa
    33961 aagtagtggg tgtttctgtc aggtaattca gggcttgctg gatttttttc tctgactggt
    34021 tatctaaagc tgaggttgct tcatctagca aaatgatttt tggctgacgt atcaacgctc
    34081 gtgcaatgga gatacattgc ttttggccac cagacagctt gttgccatgt tcgcctacta
    34141 aggtatccag accatcagga agctggtcaa tcagtgaaga aagttgcgca gcttcgatga
    34201 cttcatctaa acgttctttt gatacgtttt tcaagccata agtgatgttc tctttgatcg
    34261 aagcggagaa caacaaagtg gtttgaggaa caacggctaa ataatttcgc acacttcgca
    34321 tatccagttc atccaaaggc tgatcatcta gaaaaatttt tcctgaagtc ggctggataa
    34381 atccaatcaa taagttaagg agtgtagatt ttccagagcc agatggccca acaaaagcaa
    34441 ttgtttctcc agctttcacc tctagagaaa aatgatcgat aatcggtttg agtgagtccg
    34501 gataaagaaa agaaacatcc tcaaaacgaa aatttccatc caaatgttgg atttttttct
    34561 taccgtgata agtttctaca tcgccagcaa tcaacagttc gccaatagaa gtgatagatt
    34621 ccatgccttt tgaaatcgta ggaatcagcg tgatcattcc agaaacggaa ttgacgatcg
    34681 tcgtgaaata cgtctgatac atcacgacat cgccgggttg gatgcgccct tgtaaagcta
    34741 atatcccagt gaaactcaaa caaatcagct gaaatatctg aaaactagcc cagctgactg
    34801 atccgaaaac agattgcagg atatctaagt ggaatccttt ttcatagatt tgagtaaaat
    34861 gcttatttaa gcgagttgtt tcgtgttttt ctaacccatg agctcgagca atcggtgcta
    34921 attcgatcac ttcgatcact tttgcagaag tctcttccat ttcttgcctg aagtctgagt
    34981 tggactgtct gatcctttta cggaaaaaga gagtaacgaa tgcggcgaga ggaacagtca
    35041 ataagaaaaa catgaaaaca acaggacttt tataaagcgt gatacctaaa gctacgaata
    35101 aattgacagc gatatttaat ccgctgacaa atacttgaga ggacaacgtt tggatagctt
    35161 ctacatcacg gatgatcttt gactggattc gtccagattg caattctttt tgataaggaa
    35221 tagatagttc ttggattttc ttgataaggg tcgctcttag tccagcttct acttgacgga
    35281 tcgaagtgct atggtatttt acatgaaaat aattcgtcaa tatattttga ccaatcagac
    35341 aagccatcaa aaaagcgttg aaataaatgg cctgcaactg agaagaatct ttcgatgaag
    35401 ctgcattgat tacattggca atagcgatcg gcattaacca agatggaaga tgtttgataa
    35461 taaaaaagag tcctgacatg gcaaaacgcc aataatttcc ctgataaaga tgcagcaatg
    35521 tctgaaaagc atttgcatga tatttttgat aacttttctg tattcgttcc tccataatct
    35581 tctccttaac aatcttggta aataaactgc aagtgttcta ttgcttcagg aacataaatc
    35641 tcaggagtag cttcaagagt ggcgtacatt agaggacgct catatttgat ataatgcagt
    35701 accgggcgga aatctaaaca gcccttgcca acaggtacca tgcggatctt tccattttcc
    35761 atgatatagt ctttgagatg aagcgctgta atataaccat gtaaattgtc caaggcacct
    35821 cggatcactt tttcctgatc agcatgattt tctttatgca tcaaattcgc acaatctaaa
    35881 atgattttta aatttggtga agctacttca tcgattaaac gtttagctaa ctgatagtta
    35941 tagattggat gattgatccc tgcttcaaca gcaacagtta cgccaaaatt ttctgcatga
    36001 gcgactaatt caatgataga atttctggcg atctgataag cttcttcagt aaaattttct
    36061 tttgtgtaac cgacagagac actaccggtt tccgtagcaa tcatcttggc ttgataggca
    36121 gagcacagag caatttgctg tttgaaagtt gccaatgctt gtgcacgaac ttcttgattt
    36181 ttgctggata ggttgatata gcatcctaaa atggaaagtt cgatattgtt tttttggaag
    36241 tattcaccaa aataggcagc actcccaagt gtcatgtcag ttaatttaag ttgttcagga
    36301 aatgcttttt gtggtgcaaa ttggatatgg gacaagtgaa gctgtgatac tttttgaacg
    36361 atttcttcac gatttcgaac atctaaatcg tgggcacgga tgcctaaatt taatggaaac
    36421 atctcaaact cctttttgta aataattagc aagaggcaga cgggattctt ttatcaattc
    36481 aacaattatt cgggcaactt tatcagcgcc ttctggacta aagtgggtat tgtcttttag
    36541 tccttctggg taatttttac aagtatcagg cataagatgc aggtagaatt tttttgtctc
    36601 ttcttttgag aaggtctgga acaattcttg tgatcttgag aacacatcta aaagaggaat
    36661 atggtgtttc tcagcaaatg cacgcatcgc ttttggatag tctccaagta tatctggatt
    36721 caatgttccg ttttctaagt aatctcgtcg cgtcacagat gtcagtaaga ccatttggac
    36781 gttcgctttt tttgcgcatt caaaaaatat ctgcagattt tttaaatagc taccgaaggg
    36841 aagcgtacct ctttcttctt ggattttctg gtcgttatgt ccaaattgta caaataagaa
    36901 atcattcggc tgaaactgtg aagctagacg ggctaacctt ccttcctgga taaatgattt
    36961 ggtgctgcgt ccattctttg cttggttatt gatctggatc tcgggtgaaa aataagcaga
    37021 gattttttct ccccaacctg tctcgggacg cttgttttca tctttttctg ccgcagtaga
    37081 atcaccggca atatggatag taggcatgtt atctcttctt tcataaaggt ttataggcaa
    37141 tgaagcagaa cagcaagaga agaagacgga
//
LOCUS       DBBGRF010000026        35942 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000026 DBBGRF010000000
VERSION     DBBGRF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.026"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..1276)
                     /locus_tag="ACIZD4_001483"
     CDS             complement(<1..1276)
                     /locus_tag="ACIZD4_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990424.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(1355..1999)
                     /gene="pcp"
                     /locus_tag="ACIZD4_001484"
     CDS             complement(1355..1999)
                     /gene="pcp"
                     /locus_tag="ACIZD4_001484"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGC5990425.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(2198..3142)
                     /locus_tag="ACIZD4_001485"
     CDS             complement(2198..3142)
                     /locus_tag="ACIZD4_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HGC5990426.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(3144..3830)
                     /locus_tag="ACIZD4_001486"
     CDS             complement(3144..3830)
                     /locus_tag="ACIZD4_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HGC5990427.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            4304..4624
                     /locus_tag="ACIZD4_001487"
     CDS             4304..4624
                     /locus_tag="ACIZD4_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HGC5990428.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            4778..5683
                     /locus_tag="ACIZD4_001488"
     CDS             4778..5683
                     /locus_tag="ACIZD4_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990429.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            5680..6453
                     /locus_tag="ACIZD4_001489"
     CDS             5680..6453
                     /locus_tag="ACIZD4_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC5990430.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(6634..8058)
                     /locus_tag="ACIZD4_001490"
     CDS             complement(6634..8058)
                     /locus_tag="ACIZD4_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HGC5990431.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            8269..8715
                     /gene="nrdI"
                     /locus_tag="ACIZD4_001491"
     CDS             8269..8715
                     /gene="nrdI"
                     /locus_tag="ACIZD4_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGC5990432.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(8780..10762)
                     /locus_tag="ACIZD4_001492"
     CDS             complement(8780..10762)
                     /locus_tag="ACIZD4_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HGC5990433.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(10776..11672)
                     /gene="murQ"
                     /locus_tag="ACIZD4_001493"
     CDS             complement(10776..11672)
                     /gene="murQ"
                     /locus_tag="ACIZD4_001493"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HGC5990434.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(11675..12736)
                     /locus_tag="ACIZD4_001494"
     CDS             complement(11675..12736)
                     /locus_tag="ACIZD4_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HGC5990435.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(12947..13474)
                     /locus_tag="ACIZD4_001495"
     CDS             complement(12947..13474)
                     /locus_tag="ACIZD4_001495"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC5990436.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(13541..15043)
                     /gene="eat(A)"
                     /locus_tag="ACIZD4_001496"
     CDS             complement(13541..15043)
                     /gene="eat(A)"
                     /locus_tag="ACIZD4_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HGC5990437.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(15301..16422)
                     /locus_tag="ACIZD4_001497"
     CDS             complement(15301..16422)
                     /locus_tag="ACIZD4_001497"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGC5990438.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            16548..17489
                     /locus_tag="ACIZD4_001498"
     CDS             16548..17489
                     /locus_tag="ACIZD4_001498"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HGC5990439.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(17639..18535)
                     /locus_tag="ACIZD4_001499"
     CDS             complement(17639..18535)
                     /locus_tag="ACIZD4_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HGC5990440.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            18804..20144
                     /locus_tag="ACIZD4_001500"
     CDS             18804..20144
                     /locus_tag="ACIZD4_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC5990441.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            20362..20805
                     /locus_tag="ACIZD4_001501"
     CDS             20362..20805
                     /locus_tag="ACIZD4_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HGC5990442.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(21309..22727)
                     /gene="nhaC"
                     /locus_tag="ACIZD4_001502"
     CDS             complement(21309..22727)
                     /gene="nhaC"
                     /locus_tag="ACIZD4_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HGC5990443.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(23130..24353)
                     /locus_tag="ACIZD4_001503"
     CDS             complement(23130..24353)
                     /locus_tag="ACIZD4_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGC5990444.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(24384..25223)
                     /locus_tag="ACIZD4_001504"
     CDS             complement(24384..25223)
                     /locus_tag="ACIZD4_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC5990445.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(25240..25920)
                     /locus_tag="ACIZD4_001505"
     CDS             complement(25240..25920)
                     /locus_tag="ACIZD4_001505"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGC5990446.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(25922..26995)
                     /locus_tag="ACIZD4_001506"
     CDS             complement(25922..26995)
                     /locus_tag="ACIZD4_001506"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGC5990447.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(27051..27289)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(27332..27565)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(27642..28313)
                     /locus_tag="ACIZD4_001507"
     CDS             complement(27642..28313)
                     /locus_tag="ACIZD4_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC5990448.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(28400..31048)
                     /gene="mgtA"
                     /locus_tag="ACIZD4_001508"
     CDS             complement(28400..31048)
                     /gene="mgtA"
                     /locus_tag="ACIZD4_001508"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HGC5990449.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(31390..31564)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            31737..32174
                     /gene="ndk"
                     /locus_tag="ACIZD4_001509"
     CDS             31737..32174
                     /gene="ndk"
                     /locus_tag="ACIZD4_001509"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGC5990450.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(32196..33062)
                     /locus_tag="ACIZD4_001510"
     CDS             complement(32196..33062)
                     /locus_tag="ACIZD4_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGC5990451.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(33222..35315)
                     /locus_tag="ACIZD4_001511"
     CDS             complement(33222..35315)
                     /locus_tag="ACIZD4_001511"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC5990452.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT        10412 a         7548 c         6346 g        11636 t
ORIGIN      
        1 atagtaattc cttcagatac tttcttgcct catcattgaa acgcagtgat tcttctaact
       61 tctgataata ttccaacgct tgtttctgag cttcagtaaa acgataatgt tttcctttcc
      121 atttgtcgat tgtctcttgc acatttccag attggatatc tttcactact agttgccatt
      181 tttcttttga gactgtacgg tctttcttat cagcagattg tatagcttct cgttctttac
      241 gcaatacttt taaaaaacca tttctgacta tccgaggaat gctgtcgaag aacccttctg
      301 taaaaccata gcgacaatat tgcttccaaa taaatagata gatttttggt tggatgaatc
      361 gttggttttt cgcaaaatat tccatctgag cagtgacttc tggtgttcgt tgacgttttg
      421 tctttctcaa cacggaaata aatgtttcaa aataagcatt aggatgtact ggcacttctt
      481 catatacgat ggattgccaa tctttacgta aaaatgcgcg atagttgatc aagaattctt
      541 ctacatcctt tactaattct tctgcaaagt cgtcaaatag ttcttttttt atctgtcgct
      601 tttttgactg cccattgatg tgttcactta ttttcttgat ttcattttcc aatgcttgat
      661 aatccgctat gtaaatcggc atttctactt ggcgaaattc tgcgagccgc tgagctaatt
      721 ttatatccgg taaatatggc tgtttcatcc gacgattttg gtacaagaca aaacagtatt
      781 tttgccatag tccttcagga aaatcgatat tcttctgctt aagccataat aattcgtcta
      841 aggccagatc aacttttgtc attccctgat ggatcgaagc tgccactgtc ggagagacat
      901 gcaggtgatc ggcaaagtgg ttgatgccta gttttaggat ctttccggtt tttggcgatt
      961 taacgatgta ttgcactttt aattctctac cacactcaca atacaatttt tgctggcttc
     1021 gttttgttcg aaaaaacgga ttgatcttga agtcagaaaa cacccaatct gttgcagcta
     1081 aataatgttc ttccataaaa cgagagctga ttagatatcg gcggtgctta tcgactagtt
     1141 cccgctgttt tttcgttaat tttgcataga tctcccaacg ttgactgctt gtgtattgtt
     1201 tagaaatttt gatgggatag cttttgctga tttcttttgg aaaccattct tcaaagacgg
     1261 attgccattc ttccacggct gtttctttcc tttctaatta caaaaagctg gctactaaca
     1321 taacgttagc aaccagccag tgtttcttgc taaattagtg agttgttccg gcatttccgg
     1381 aaatatcttc tttattttct actgctgctt caactgcata agtcaaagaa gaagcaatgt
     1441 cttctaaaga catagaaggc gtacccactg gacgatcgat cacttgatcg ggtgagaatg
     1501 gcacgtggat gaacccacct cgaattgccg ggaattgtgt ttcgatcaaa tgaagcaaac
     1561 gatacatgat atcattgcag acaaatgttc ctgctgtata agagatgtac gctggtagac
     1621 catgatcttg tacatttttt gtcattgctt tgattggcaa tgaggtaaag taagcggctg
     1681 gaccgttttc ttctaaagcc gtatcgaatg gctgatttcc ttcattatca gggattcttg
     1741 cttctgctag attgattgcg acacgttcga acgagactgc tgaccgccca cctgcttgtc
     1801 cgacacagat cacgacatct ggttggtgct gttggatggc ttctttgact acttgactgc
     1861 ttttttcgaa tacggtcggt acttccactt tgatgatttc agcaccgctg atttcatctg
     1921 gcattttttt tactgcttca taggctggat tcactttgtc cccaccaaat ggatcaaaac
     1981 ctgttactag tactttcatc tgttgttcct ccgtccgatt gatttaacat atggttatct
     2041 tttatcatac cattttcctt gaacagcgta aataaaggaa acaatagttt aaataacata
     2101 acagatcaaa cttaatatat tcttataaaa aaatagtgtt ccactacaat gttagaagag
     2161 gttgcgacaa ttattctgtc acaacccctc tcttctatta tttaaataga atcatataag
     2221 caatttggaa aactagcata aataacgcaa taaacaactg gtttttgatc actccgtatt
     2281 tgtctttcat ctccagcatc gctacaggca cgatattgaa gttagcagcc atcggtgtca
     2341 gcagggtccc acaaaaaccg caagtcaatg caaccattcc tattaacgct ggattcgctc
     2401 catgactaaa tacgaatggt gcaccgatcc caaccgtcat cacggtgatg gccgcaaatg
     2461 cattccccat gattaccgta aatatcacca tgccaagagc gtaaatgatg atgccgatgt
     2521 tcacatttcc ttctggaacg atcgtaccta ctgcattgga aatcactgtc ccaactccag
     2581 cgcttgtaaa taccgcacct agagaagcta aaagcattgg caacatgctt aacggcccta
     2641 ctgtgcccag catatctgct gcatcatcta aaaatgtact tggtcgatta tctcgagaaa
     2701 agaacatcaa gattagcatg gctgcaaaaa caccgacgcc cacgccgact aaagcaccta
     2761 aattggtaaa tagagcaaac aagatcgcaa agacaccgat actcaaagct ggaataaaaa
     2821 ttttcattcc tagtttgtct gacatttttt ccatatattc ttttgatgga agccggcttt
     2881 ctcctttgct gactttctta gcaattgctg gtatggtcat cgcaaagatc aagccaccgt
     2941 tcacgattgc cggaagccat cttcctcctg caataactac ccctaagacc gtccagaaaa
     3001 aggctgaccc ataacgatga ggattggttt tatctgttaa atttcttact ccagtgtaaa
     3061 tcaatacgag tcccatcacg atataaagga tctccagtaa tttatcgcct aataaaatat
     3121 caggatttgt aaaaaagtcc atcttattgc ccctttcctg gataatattt cttcgctaat
     3181 ttcttttctt taagatagaa gtagacactt gccacaacta aagccgtgat agccactgga
     3241 acttccacta aagcaagctg tcccaatgtt acgtcatatc ctagatcttt cagtgttgat
     3301 tggactagca acgcccctgc tcctccgatg aatagtactt ggccaaagaa ccagcagaca
     3361 ttttccatag ctgaagccat accttttagt tcttcttcat gcttaggatg gacttctaac
     3421 ccttttgatt cgatggtccc caatgccatc ggtaaaatga ttggacgaac aaatccagca
     3481 actccaccaa aactcacgtt aaaagccgca aagatcattc gaaagatccc ataaatatct
     3541 acaatcatac cagcagatac tttcttgaat cgcttgatca aggaagccgc tgattctttc
     3601 agaccatttc tttcaagcgt tcctgttgcc aacataatga tgataaaaat cgccatcccg
     3661 cgattgttta caaaacttgt acctaaaagt tctaacattc cttgaatgcc aagaccgcca
     3721 gtcaaagctg taacaactaa agcaaccatt acgatcaata tcgagtctaa tttaaatgca
     3781 aacccgagaa taacaatcaa gacgcctaaa aggctaagat aattttccat atattttcct
     3841 ccataaaatg acaatatttt tttaattata aagcaaaaca cataaaaaat atagttgttt
     3901 tctcacgaaa tagacactat ttttaaatat ttttcgttat ttttttatca caaaaattat
     3961 cttacttatt gtaaggtaaa gcttttttta atttattgcc cgataatata tagaaataag
     4021 gtctagttac tgtttttttt aaatgattaa taaataacaa cttctttcta tgaaattgca
     4081 aagcattcat cttcttttcc gctaacgata tatccgtcag tgcttggtac actttactaa
     4141 aaagtatgag attgccgata tctggatagg tgtgctatac tacagaaaaa gatatacaat
     4201 ctgccaccgg gtaggataaa gaggatgatc attccattag gtctttgaag ggatgatttt
     4261 cctctttttg tgtatttttt tatagttaag gaggaatgta agtatggcat ggatggaatt
     4321 aatcatagca ggaattttgg aagtattctg gtcaacgatg atgaaatgga gtgatggttt
     4381 ttctaaaatc aattattctt tttacacagt gattggcatg attgctagtt tttacttttt
     4441 gtcaaaggca atcaaaagtt tgccgatgag tctctcttat cctatctgga cagggattgg
     4501 cgcagttggt tcggtcataa ttggtgtggt cttgtttcat gataagctga atctttccac
     4561 ttggttcttt gtggggatgc tactcatcag tatcattggc atcaagatta ctagcggcca
     4621 ctagacactt ggaataagta ctgatcagaa aaaataagcc tttttattta atattcaatt
     4681 tttttatgaa aaaataagaa ataagtccaa tgacctagcg acttctccac tcatcaggtg
     4741 tatgcttgta ctatctatag aaaaggagtg aatatttttg aaaagtcttt cggtccaaga
     4801 attatccaag aactttggtc acaaacaagc cctcagcgat gtcagtttta gcttatcccc
     4861 tggcaaaatc gttggattag taggtcctaa tggcgctgga aaaacaacga tcatgaaagc
     4921 tattttagga ctgatccatt actcagatgg aacaatctgt attggtgaaa atgagatttc
     4981 tccctctagt cataaagggt tggaacaagt aggagcattg atcgaatacc cgggtatcta
     5041 tccattctta acaggctatg atcatctgaa gttattctct gaaaccaacg atgtatctgc
     5101 tatcgacact atcgtgaatc agctcaagat ggaaaagtac attcacaaaa aagcgaaatc
     5161 ctactcgttg ggaatgaaac aaaaattggg aattgctctt gccttactga accatccgtc
     5221 tatcgttatt ttagatgagc cgatgaacgg tttggatcca caagcaacaa gagatgtgcg
     5281 aaaaatcatt accgacttgg ctactcaggg cacctctttc ttgatctcca gtcacttact
     5341 cagcgagctt gaaaaaatgg tcgatgagct gatcctgatc aatcaaggaa agatcatcaa
     5401 acaatgtaca atggctgaat tgaaccaaac agcgcaagat ttcatcgtta tctctacaac
     5461 aaatgatcta gctgctcgaa cgatcttgac agaagctgga tatactttgg aagatcctga
     5521 taaaatcaag cttttaaaag aaaacgaaga attattagga accgtgatcc agctattgtc
     5581 tgcacaaaat atccatgtga cagacgtcca gcatctgacg aatgatttgg aatcttctct
     5641 attggaaatt ctggattcag taaaggggga agaagaaaaa tgacattgct tgtaaaacaa
     5701 gaattattta aattgatcaa gaaaaagtca actgctgttt tatctgttct attagttgtt
     5761 ttgctcatag gaacagcact tctagccaaa aaatacacga cgatcattga tccagttgaa
     5821 atgactgctc agctttttag tgccacatct tggattgtct ttatcatgat tgcagctgca
     5881 agcacgatca tttcgatgga agcacaatat ggtacattga aaaatctcct ttatcgaaag
     5941 tattctcgag gagaaatatt agtaagcaaa tggatcacat tagttattta ttctgtttat
     6001 ttataccttt tagctattat tgtcactgtg ttgatgaaac tgattctttt cccttcgatt
     6061 tccttcacgg agaaggtttc tactggtcaa acactgatcc aaagcttgtt cacttatact
     6121 ttgggtagtt atatcggttt atggctgatt ttaagtttag tgttgatgat tgcttgcttt
     6181 atcaatagtt ccggcgcatc catctcagca ggaatcgtct tttattttgc ttcgtcaatc
     6241 atatctggta tccttattgc actcatccaa aaatgggagt ggatcaaatg gaatccgatc
     6301 agtatgttga atctgcaaaa ccaaattgga aacgaagaga tcatgaagca attgactcat
     6361 ctttctacta atcaaatgct attcggtaat ttagcttaca tcgttttgtt cttagcatta
     6421 ggatatctcg tatttaagcg aaaaaatgta tgatgactca tcaaaaaaga ggctgtgaaa
     6481 gagacgttca gccttattgc cgattggctg tctcttaaac accgtttatt ctgaaaaagg
     6541 agctgtgaca acatttgtgt cacagctcct ttcctagtat gtttttgaat aaacgacagg
     6601 ctcacaacct ctctttatac ttcttttata cttctatacg tgaagcatcc cagtggcaaa
     6661 taaaaccatt gcaatcactc cgaccatcgt cacacctata agtaaaatct tatctaagtg
     6721 gatatgttgt acaggctcgt tttgctcctt acgtgctttg aggtaaaaat aaatgcctgg
     6781 caagaaaaga acaagaacaa gcattacttc attaaaggct acgactagca tagcccatac
     6841 ttgaaaggca cttgctaaaa gccctactaa aaattggacc cattctttcc gctgataaga
     6901 aagtttcatt tggtacaatc ctaagaaaag ccacgtgaag aaaatagctg ctgtaccaag
     6961 tgtgtaagca aagttataag cactgtcagt gaataataat gaaagtaaaa agacattcgt
     7021 acataacgtc gtcaatacga tagcataagt tggtgcccca tttttgttga gttttcccca
     7081 tgctttaggc aaaagtccgt cttcagccat gtttcccatt gtttcaatcg gtaagatcgt
     7141 ccatgagagc caaacaccaa ctaaagaaat gatcaaaccg ccgttgatca cgactgctcc
     7201 ccatttacca accatcattt caaacacata gcccatagca ggctgcgcct tgatcgtttg
     7261 cagctgattc atcgtcattg tcccatatgg aagcatggaa accaagacgt aaataataat
     7321 caagccgaat atccctagaa tcgttgcttt cccaacatct gattgttttt ttgctcgtga
     7381 acctacgaca gaggctcctt caataccaac aaatacccaa agcatcacca tgatgcaact
     7441 caatacttga ctggaaaacg ggatcggctg tccattcgca ttcaatataa tgtcgctaga
     7501 aaagttatca atgaattgtt ggatcgaaaa cgtgctgata gctactacaa taaataaaaa
     7561 taatggcact aatttacaga atgtgacgat agcattgacg aaactagcat tttcgactcc
     7621 ccgattcact agccatgcat atccccataa aaagactgta ctcatcacga tcgatgccag
     7681 attttgccca ccttcaaata ctgggaagaa atatcctaat gcgctcatca acaatgttgc
     7741 aaaagctacg ttgcctaacc agcatgtgag ccagtaaccc caaccgctga taaaaccagc
     7801 gaaacggcca aaaccttctt ctgcgtaact aaagatcccg ccttttaaat ctggacgttt
     7861 tttattgata ttattgatcg acaaggagag catcaacatt gctgttccta cgagtaccca
     7921 actgaaaata gctgggccgc cagccgatcc ggagatgtcc gtcataatac caaatacgcc
     7981 acctccaatc gctgaaccaa ttactaaggc agcaagtgga attaaaccaa ttcctttttt
     8041 ctgttgctct gtatccatgt aagcatcctc caaaataaaa ccgcttttat caaaaagtat
     8101 aacaaacctt ttttattttt acttaattaa taaaaacttt aatagaaata taattctacc
     8161 ggcttttttc tcattataca agcaaagcgc ctagtccctt tccaaattac accaccaaaa
     8221 aacttaaaaa agatgctata ctaaaaggaa agaattggag gatgatccat gaacatttta
     8281 tatatatcga tttcaggaaa tacgcgtgcc tttgccaaac atctagcaga atatgctgaa
     8341 aaaatgcatg cagaagatcc tgtcaatcct gaagttactt taaaagaaat ccatgaaaat
     8401 agtgatttta cgaaagaaac agaaccattt tttactttcg ttcctactta tttagacggc
     8461 ggaaatggtt tagataacgg tgatacagaa atcttgaccg aaacgatgcg tgaatatctg
     8521 gaacatgaag acaatcataa actttgtctt ggtgtagtcg gtagcggaaa taaaaacttc
     8581 aataatcagt attgtctaac agccaaacaa tatgcacaaa catttggctt tcctttcttg
     8641 gcagattatg aattacgggg aacaccatct gatgtgacac gaatttatca gattttagca
     8701 gaaaacaata aataataaaa aagaagaagc tgaaaaatag atttcagttt cttctttcgt
     8761 ttctattgtt tctatcatat taagctttga catccatcac aggtgctttt gcttttgctt
     8821 tacctgtttt ttccaagaca aagtttttta cacgatccat attggttacc aagacgatca
     8881 tggatgtttc tttgcctgct gctttgatcg cttctaagtc agcttctgct acaagcgtat
     8941 caggtgtcac ttgctgccct tctgttactt tcacatcaaa tggcgtaccg cctaagtcaa
     9001 ctgtgttgat tcccatatga agcaagattt ctaaaccatt tggcgttgtg atcccaatag
     9061 cgtgtttcgt tgggaagaca gagctgacta ccccagtaac tggagaatag atatgtccgt
     9121 tttctggttc tacaaagtag ccttcaccca tcatcttttg tgcaaaaact ggatcacttg
     9181 ctttatctaa agaaacaact gttccgtcag caactgatga gaggatagtc acactttcag
     9241 ctgaagtttg aggtactact ttttcaggca cttcatttac tgtggctgtt tcagtcgcta
     9301 attcttcttt ttctaaacgg tctttaggaa taccgaagaa gaatgtagca acgaagccac
     9361 cagcataagc tgccaataat ccaaggatgt agcctaacca tttaccgtca gagatcaatg
     9421 ggatcaaagc ggctcctgaa ggtccaatag cgatagcccc gacatttccg atcattccga
     9481 tcactgcccc gccgatacct ccaccgatac aagcagtaat aaatgggcgt cctagaggta
     9541 atgttactcc gtaaatcaat ggttcgccga ttcctaggat cccgactggt aaagctcctt
     9601 tgatcatttc tgttaattct ttatcttttt tgcagcgaat ccataatgcc aatgctgcac
     9661 ccacttgtcc tgcaccagcc atcgcaagaa ttggaagcaa tagcgtacga ccagtttcat
     9721 caatcatttg cacatggatt ggagtcaaaa tttgatgcag tccgaacata accatcggca
     9781 agaataatgt gcctagaacg aagccggcaa atgctccacc aacgccaagt acccagttga
     9841 tcccaccgac catgccatca gaaatgaaac ctgctaaagg catgatgaag aaaatttcaa
     9901 tcagaccgat ggcaatcaat gaaagagttg gtgtaacgat gatatctacc gcatcaggta
     9961 ctactttatg cagttttttc tcaacgattg acaatagcca aacagcgaag atgacaccta
    10021 ggatcccacc ttgtccagct gcaagagctt caccagtaaa taagtttttc agtggtgctt
    10081 ccggattcat ccctgtcagc atcacaacgg ccccgataac tccaccaaga gttggtgttg
    10141 caccaaaaac ttgtgcagca ttgatacctg tatagataac taggtagcta aacatcccgt
    10201 ttttcaagat gttcatcaca tcgatatatt gttgccatgt tgctgcatca agtgttccgg
    10261 ctgtgactaa gtttgctaaa actgcggcaa tccctgccac gatcccagta ccgacaaatg
    10321 caggaatcat tggcacaaag atattagaaa tgtcttttaa taccgatttg attttagatg
    10381 gtttttgttt cgatttttgt gccgctttca tttcttgtgc ccgttcgttt acacggtctt
    10441 ttccagatgc tgatgaattt gctgtagctg tacttacaga agaaagtttt tctcctaatt
    10501 tcacgcctgc caaatcaacc atttgctgtg ctactttgtt cactttccca ggtccgatga
    10561 tgacttgaag ctgttcatct tctactacac caagcactcc tggaatcgct tttaattcag
    10621 agacatttac aagatcatca ttgatgatct tcatacgcac acgagtcatg cagtggacaa
    10681 tgctttctac attgcccatg ccgcctgccc ctttataaat ttgttttgcc agttcttcca
    10741 aagtcagttc gttttttgcc atggtctttt ccccctcata aggtcccttt tacaaatccg
    10801 tttgcttcag ctaattttgc ttgagcttcc tctttatcac tatttgtcaa aatcatgacg
    10861 atagccagct taacattttg atctgcttct tcaaagtact tttcagctgt ttcgtaatca
    10921 gcttctgtcg cttgcatgat gattcgtttt gagcgttcga ttagtttttc atttgttggt
    10981 ttgacatcga ccatcaagtt attgaatact ttacctatac caatcatact gatagtagaa
    11041 atcatattca agataagttt ttgtgctgtt cctgacttca atcgagtaga gcctgtcaaa
    11101 aattctggac ctgcatcgac ttcgattggg aaatccgcgt gtttactgat ttcggcttgt
    11161 ttattgcaag aaatcgttcc tgtgacagca ccgatcgatt ttgcgtaatc taatccaccg
    11221 atcacatatg gtgtacgacc gctagctgcg ataccaataa ctatatcatt ttttgtcaaa
    11281 ttcagcttga ttagatcttc ttgccctagc tcataagaat cttcggcccc ttcgacagct
    11341 acagtcattg cttcttctcc accagcaatt agacctatga ccatttccgg ttctacaccg
    11401 aatgtcggta cgcattcagc agcatctaac acacctagtc ttccacttgt tccggctccc
    11461 atataaatca gacgtccacc ttttttaaag gactcaatcg tgttagcaat cactggttcg
    11521 atacttgtca gttctttttc aaccgcagcg gccactttct gatcttcttt gttcattagt
    11581 tgaacggctt gagaaatact catctcatct aatccaaaag tttcttggtt tctgcgttcc
    11641 gttgttaggt tctctaaatt gattttgctc atttttatct tccttctttt cttataaatt
    11701 gatagttcat accagctttg atttggttga tcaatggtag ctcttctttg ataactttag
    11761 ctactacatt cactttttca tccgctggca aatcatattt ggttaattgg atctcaccca
    11821 tatagcgcaa atacttttcg ttatctaaag taatagaccc tttcatacgc gtagctgtat
    11881 ttcttgctgg gataggcgga atctctcgaa aacgtgcatc tacgcttcgt atgacatctc
    11941 ttgcatcgtc ttgccgattc gtatgcttcc ctaatatata ttcgtaaaat tcttcatcta
    12001 caggttccgt atggagcaag actgtctgtt ctttttggaa agaagcaaat tgctcctgaa
    12061 cgttttctga cagacctgca tctccgatgt aaacaatatc cgtgttactt gctaatagat
    12121 ctagagcgcc tgcaagagga tggatccctc gatgttcttc caaagttggc aatccttgat
    12181 atagtgggcc tctcaactct gtatctcctg gtacaaaacc ttggacaagg agaccttgaa
    12241 ttttgagcca ttgatttttt ttctgatacc attctttgtc cagccctgtt tcgggacgtg
    12301 gataataatt atgccaagct tcaatctgtg agaaatcagc ttctgcttct ttcaattcat
    12361 cgatatcttt aggcgtgatc gtgctagcat tcaaactgat tttcaattga tgtgaccagt
    12421 cggcaatctg ctgattggaa atatgataat ccattcttaa acctgttaca ccaattgctt
    12481 tcaaaggcgt tagatcttct aatgaaaaac ccgctcgttc caatgcctct cctgaaatat
    12541 cgaccatcaa ttctagttta ttctttttcg cttcgcttcc tagttcgatc aatcgctttt
    12601 gatatgccga aacatcatct tctggtatat gcatggaagt gaaaataccg acaaagccat
    12661 tggatgccat ttggcggata tactgtttct tctcttctga caaagaatcg ttcataaata
    12721 ttgaaaagcc aaacatatta tccctctttt tctgtatccg tcttcatttc tatgactaga
    12781 gtatatatct aaagaaacaa aatttcaata cttttattaa aataattaaa tttcatttct
    12841 aaaggttgag tttatattat caaaagaatt gtcataacct aaaaaaggca ctgctaagca
    12901 aaagcagtgc cttgaaatat tttatttaaa taacacaaaa acataattac tcataagaaa
    12961 ccaattctgt attatctacc atgaatgtaa agaacccctc attaggcatc ggatgaaaat
    13021 aagcattgat cactcttatc aaggcattat ggcaaactaa cagatagaca ttttcttcgt
    13081 cttcgatgca ttctttcaat aaaggaacga tccgtgcata cacatctaag actgactccc
    13141 catttgggaa tcgtacagcg aacgctaaac gtgctttttg aaagttctca tctttgcttg
    13201 gcagtccatc ataatcccca aaatccattt ctaccaatcg ttcatcaacg gtcagcggca
    13261 agctgagacg atcagcaact gcttgtgctg tatctcttgc tcgttgaaga ggggaatgga
    13321 tgattttcgt gattggaaca ggcaaatcta ctaccttttc tgctagtttc tgtgcctgca
    13381 tctgtccttt ttcagtcagc ggcacatctg cccgtccgca aactaatcct tgtgcgttcc
    13441 aagttgtttc tccgtgtctc gttacataaa gcatgtgatt ctctccttcg ttggcaaagt
    13501 tccccttaac cataccttgt tgttcttgag attacaaggg ttagattctc tcaagagaaa
    13561 taatctcagt agatacttta tccaggaagg tttgatcatg ttccactagt aacatggcag
    13621 gtttcacgtt caagatcagt tgttctaatt gttcttgatt gaagacatcc aaataattca
    13681 atggttcatc ccatgtatat agttcagctg gctgtgataa agatttagcc aattccactt
    13741 ttttccgttg gcccatactc atctgctcga tcttgttatg aaaaacatct ctttccatcc
    13801 caagctttcg gaggttgttc aaaaatgctt ggtagtctac ttggtttttc tctgcaaatt
    13861 ccgccaacgt tcctcgattg tcttcataat tttggcttgc ataactaatg ctcagatgtt
    13921 ttggctggta tttttctcct ataaccttgc cgttgaatgc ccccagaaga taatggataa
    13981 tggatgactt tcctgcaccg ttaggacctg aaatcgccac ccgctgatga ggctcgattg
    14041 taaaatgaat tggctcgaat aacagatttt cataccctaa ttgaagatct tctacgctta
    14101 aaagtcgctt atggtgagac gcttggctat tcatcgtcaa agaatcgata tattcgatat
    14161 cttttaatag tttttctttc tcgctgatct gggtctccat ccgattcacg attgctttgg
    14221 atcgtttcat cgtccgtgca gcatcagcac ccactgctcc tttattcact cgtctagatt
    14281 cagtatcgat gaatccgact tgtttctttg ttttatctcc ttctcgggaa cgagaccatt
    14341 cggctttttc agctgctgtt ttctttagcc tactgacttc ttttttcaat ttttcatttt
    14401 gagccatttc aaattcatca cgaagttttt tctgttcttc atagatagag aaattccctt
    14461 gataaagttc cagttgactt ttttcgattg ctaaaacatg gtccactact tcatcgataa
    14521 atccccggtc atggctgacc acgatgaagc cttgtttttt ctttttcaaa taagccgcta
    14581 cttgttttct accagagata tccaaatgat tcgttggttc atcgattaac gggaaatgag
    14641 tgtcatccac aaataaaagt gccagtagga cttttgtctt ctctcccccc gatagtgtgc
    14701 tgaattctct ccataagatt tcaggatctg tttgcatcaa ttggagctct ctttcgattt
    14761 cccatatctc aaaatccgta atatcattta acacgtaata ggttaaacgt tctttatctt
    14821 ttgtctgttg cgggaaatag gcaaattctt gctgatggat tacttgccct tgataaggta
    14881 gtttgttttg tagaatattc agtaaagttg tctttcctcg accgtttcgt ccgataagtc
    14941 ctagtttcca ttgtgtgtca aaatttagat ttgcttgttc aaataataat gtgccttggc
    15001 tgtcgtagcc gaatgtcaga ttttttattt cgattttaga cattttccat cacctcgtaa
    15061 aaaaagacca gtcctatttt cagaactggc taaagaggat gcaagggttg gatacacaca
    15121 aaaagaccca tacatcgaaa aaaccaagcc aatcccgaaa atctgcacac tgcttccttg
    15181 tctccacaag gtacagtctg aatgcagctt tcatcaatcg acttaatttt tcaatgcacg
    15241 gatccctcac tttgtcctat atttgaaatt acgatagcat aaagaaaatg attttgtcaa
    15301 ctacttcggg aggatggtga aaaatctgct aagtgtctgt cctaagattt ttgttttttc
    15361 taatgtttgc ctgtgttcca ttgcttcttc taaacctatt ggacccaaat gaatacttaa
    15421 gacaattggg agaaaatcag aaagtccttc tagctcttgg tctctacttc cgcaaatagc
    15481 gattattggt tttcgatatt tttttgcaag cactgctaca ccgtatggaa cttttccgtg
    15541 gatcgtttgc tgatcgatcc gcccttctcc tgtaatgatg acatctgctt gttcgatctt
    15601 tttttccaat ccagtgattt ggctgactaa atcgaaacca gaaaccatct tcgctcccaa
    15661 caaaaaaagg gctccaccaa taccgcctgc tgctccactt cctggaatat catctaaatc
    15721 cacctcccag aaatctttta tttgctgagc aatctttcct gcttgtttat ctaagaaagc
    15781 tagcgtcgta tctattcctc ctttttgtct tccaaattgc caagcagctc cttgttgacc
    15841 tgtatatgga ttggtaacat ctgcagcgat aatcaatttt actttagaaa caagaacgtt
    15901 tcttcgatca aaatgaagtt ttttagtaga taataaagga tttccttctg tgtacccttc
    15961 taaagaagca cccaaggatt ggagtaatcc tagaccacca tcgctacacc cgcttcctcc
    16021 taaagtgaca ataatttgtt ctacttcttg aagcagtgca tctttaataa gttctcctaa
    16081 ggcataactg gaagcaagtc ggatagtttg atccgttggt ttatcaagta gatctaaccc
    16141 caatgcttgt gcagattcga tgactgcggt gttttttcct tgccaagttg tcaataaata
    16201 gctgattttt cgctgacgga ataagagatc catcccatca atggtacgcc atgttcccct
    16261 gagcgcgtaa tagattgctt ctgcagtatt ttctccgcca tctgcaatcg gcacattgat
    16321 ttttcttcct ttacgatctt cccagccatt tagaactgcc tgatttagtt caaatgaaga
    16381 agcacttcct ttaaatgaat caattgccgc caaaatatcc atctgtatcc ctcactttct
    16441 tcttaagtaa gacacttttt ttcatttttt tcaaacaaaa caatgctatt ttcttccatt
    16501 tttctatata ctaaaaggga actcattgaa taaaggagag aaaaaacatg aaaatcgcaa
    16561 tagctggggc cggagcaatg ggcagccgaa tcggattgat gctacatcaa agcggaaatg
    16621 aggtcctctt gatcgatcgt tggcctgctc acattgaagc cattcgtaca aatgggttga
    16681 ttgctgactt taacggtaaa gaagtggtcg caaaactgcc aatctattca ccagaagaaa
    16741 tcatcgaaag caacgaacac gtggacttga tcgtagcatt aacaaaagcc aatcaattag
    16801 atgatatgtt ttgttcgatc caatccatta ttactgacaa tacttatgtt ttgtgtttac
    16861 taaatggatt aggtcatgaa gatgtactgg aaaaatatgt gccaaagaaa aatatcttat
    16921 ttgggatcac gatgtggaca gctggtctag ctggtcccgg aaaagtcaca ttgttaggtg
    16981 atggagaaat cgaactagag aacttggaac cagaaggcga agcatttaca aaaaaagttg
    17041 tagaagtctt tcaagaagca aatttaaatc cgatctatag ccataacgtt cgttattcca
    17101 tttggcgaaa agcttgtgta aatggaacat tgaatggttt atgcacgatt ttggattgta
    17161 atattgctga actaggcgcg caaaaagcgg cagagagcat ggttcgaaca atcgtatctg
    17221 aatttgcttc tatcgcagca aaagaaggaa tcatactaga tcaagaagaa gtgtaccaac
    17281 atattgcttc tacttatgat cctgacaaca tcgggttgca ttacccatct atgtaccaag
    17341 acctgatcaa aaaccatcgt ttgactgaaa tcgactacat caatggtgcc atttggcgaa
    17401 aaggacaaaa atatgatatt gctacaccat attgtgcctt tttgacccaa ttagtccatg
    17461 caaaagaagg aatccttggc gcagaataaa aggctctctg atgagaatca gctgaatcag
    17521 cagctggttc tcttttttta agcccaataa aagatcaaaa agaaaacaca actctcatga
    17581 tgccataaga attgtgcttg tttgtttcag tacataatct cttcaaaatg taggtttttt
    17641 atttgttttc aacagaggag aggtcatatt cgtattgctc ataaatagtg gaatcgttag
    17701 tgataaatcg ttttgcccaa ttttctgcat cataaaattc caatagctct gataggattg
    17761 gcttaaatgg tgtatgcaga aattccggta attcatctaa atcacgttct cgaagcaaaa
    17821 aaatattttc aggacgataa aaatgataat gagcaatcgc ttgattatcc gtcactagtt
    17881 tcttttgaaa atacatggat tcaaatgtcc gcaaagtcac tccttgctga ccctcccgca
    17941 acagttccag aatcccgcgc gattcccctg tttttttcag gtactcttca taagtaagat
    18001 atccaggttg ttcattccct cgatgtggaa gaatgaaata gttggtcgta acatctcttt
    18061 ttataaattc ctgcttatag ctttctgctc gttcttttct cccattattc gttgcaccaa
    18121 aaaatagatc cgtctttggt tcgctagaag aaaaattcat atgtttcgaa taaaatgaac
    18181 tattatgttt cagcccaagt tcttttgctt ccaaaaaatc aaaatgataa atctcatcga
    18241 ttgccggttc atcttgtgcc tgcttcagca tcgcctcgtg ttctgctttg aagtgattcc
    18301 aaaaaaataa cacaattttt gcattggtaa atgggcgcac gcgtcgagcc atctccatat
    18361 caaatccata atctaaaaaa acgatcagct gataatttgc caactgttgt ctagctgatt
    18421 taatgaattc cgactgtagt aaatcttttc cggaccaaac atctaaagag cggatggaag
    18481 gcaaaaaata aagtgattta ttttttgcaa ctagcagtac gtcatttttg ttcatctttt
    18541 ccgcctcact ttctctgtca ctttttccta tgatagcctg tttaaatagt aaaaagccag
    18601 taaaacgttt cctatatttg tatgaaaatt taacatttgt atgaaaatat gatgaaataa
    18661 atcattcttc tattaaaatt cgcctaaaag ttttctgaat agttgtaatt gtctgaaaat
    18721 ttgttatcat tagtcattgt taaatattgc tatttattct taatataaat tttgattgtg
    18781 aatttaaaag aaagaggtca tttatggaag ataaaaaatt gaaaaaacaa cttagctcca
    18841 gacatatcac catgttagct ttaggtggag caatcggtgc aggtctattt aaaggaagtg
    18901 gcgaagcgat tgggatcgcc ggcccttctg tattgattgc ttttttgatt ggtgggctga
    18961 ttttatatat cgtgatgaaa ggtctgggaa aaatcgtttt aagcggtggc gacacgcatc
    19021 acggattatc tggtttgata cgcccttatc taggtgctca ttctgctgat tttactgatt
    19081 gggtctactg gtctatgtgg attatcaata tcatcgctga agctgttgca gctgcttcct
    19141 ttttgcagtt gtggttcccg cacattccag cctgggtatt tgtttttatg ttggctgttt
    19201 taactacgat catcaatctt tattcggtac ggttattcgc agaaacagaa tattggctgg
    19261 cttttgctaa aatcagtgtc attatcttac tgatcatttt tgctacttat cttgtcggtc
    19321 agcaaatgtt gggcacaggc gttttcccta cccttcagca attgactgac catggtgggt
    19381 ttactcctca tggtatgaag ggaatcatca gttctttgct tgtagttatc tattcttacg
    19441 gcggttctga actgattgct atcacggtaa gcgaagcaga tgatcctaaa cgtgcgattc
    19501 ctaaagcaat caaaggtgtc atgggaagaa tcatttcctt ttacatcatt cctttgtttt
    19561 tgcttttgat tctttttcct tggaatactt tagcaggcac gaatgtcagt ccttttgtga
    19621 tggtatttga aaaaatgaat atcccatttg cagcggatat cgtcaatttt gtgattgtcc
    19681 ttgctttgtt ctcatctatc aattcgggtg tgtatgcatc ttcaagaatt ttgttcttcc
    19741 gtttgaagga tcgaaaaggt tcctctagaa aactagctgt tttaaacaag catcaagtac
    19801 cgcaacgtgc tgttttattt tgtaccagtg ttctttatct tggtgtagct ctttcttatt
    19861 ttgtcggtga caaattattt ggctatctgg caggttccct ttcgtataca gtattattga
    19921 tctggatcat tatcagtgcg gcatcctttg tactggcact aagaaaagga acattatggg
    19981 ataaaggaat cagctttttt gcattagctg tcttaggatt gattttcctt ggtatcctgt
    20041 tcacgaactc cattggggta actgtattga ctggcctgct ttacctgttc atttatttca
    20101 gttatcaaaa aaagaatgat gcgttcgtat tgacgaatga atgaaatcga tagaaaattt
    20161 tattttattt atgtggaata gatggagcta ttgaagaaag gagttgtgac aaaagtcttg
    20221 ttgcaactcc tttttccgaa taaacagtct catgacctct tggtaaacgg tgttcaaaaa
    20281 ccctctgtgc aaaataattg attgttctcc atgctcatga catgatagaa gaaaggaatg
    20341 aaaaaaagga gtttgtttta aatgaaaaag tattggaagt ttttgttgat gatcggtgtt
    20401 tcaacggtag ttatgtttgg tatgatgtac ttgaatgtct atgcgctcga tcatatcttc
    20461 ttcagtcgta cacgagtatt catggcgttg atgatgggtg cagtcatggc agtcatcatg
    20521 ctgttgttca tgtggaaaat gtatgaaaac aaaaagataa atgttatgat cttagccgct
    20581 agtcttcttg tttttgccgg ttccttgttt atggtacgaa gccaaactac tgtcaacgac
    20641 acagcttgga tgaaggccat gattcctcat cattctatcg ctatcctggc aagtaaacga
    20701 gctgatttaa aagatcctga agtaaaaaaa ttagcggaag aaatcattca ggcacaagaa
    20761 gaagagatcg acaaaatgaa aaaaatgatc aaagaaatgg aatgaccatt atccgtccaa
    20821 ataaaaaaag aggatgttcc agaagttatc agcttcaaga aataagaaga agctacttct
    20881 ggaacgccgt gaataagggg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
    20941 aaacaaaaat agcttctcct atttttcgtt tggttaggct tattaccgca gatgcaagct
    21001 tttgaacacc gtttattaag aggttgtaaa atcagcgttc tgacctgagt attagagaga
    21061 caaatggaaa aatagttcct catattttgc cattttttga gctaataccg agggtcagct
    21121 gattgaacac cgtttatcga gaggttgtga aaaagtcgct tagtttcgcg tattaagaaa
    21181 aattttgtga aatggctttc cacatttttg tataaatttg gcttaatacc gagaaactgg
    21241 cttttgaata ccgtttattc gtaaaaggga ttgtgacaaa agtcttgtca caatcccttt
    21301 ttatgttttt attgttctaa ttgcgctgtc ttgcttactg cttcttgcgg tttcacaaat
    21361 ttttttgaga ttccccaacc tgtgaaggca ctgaccatcg aaaacacagg agaaagcaaa
    21421 ctgaaaaata cgaatggcaa gtaagtgagt gtaggaatac caaatgtact tgctacgaaa
    21481 cttccggcaa ttccccaagg cactaagtag ttgattactg ttccaccatc ttctagcgtt
    21541 ctacctaata cagttggatc aaatcctgct ttttcataag tttctttaaa tgcattacca
    21601 ggcagaataa cagataggaa ttgttcacca ataaaaatat ttactccgat acttgtcatc
    21661 aatgttgtaa aaatcaaatt tggtgtgttc gtcatctttc ttgatactcg ttccatcacg
    21721 gttgagatca agccaaattc gatcaacaat ccacctaatg acaaagttag aataatcaat
    21781 gacacagtag gcatcatact ttcgattcct ccgcggctaa gcagtgaatc gatttgttgg
    21841 tttccagtat ttgaaacaaa ccctgattcg atgaccccag ccaacttcgt taaggaagtt
    21901 tgtgggtttt gaataaaaat cattcctact gctacagcga tattcaacaa aatcgttaaa
    21961 attgccggca cctttttcca tgcacacagt aacattaaaa ataaaggaat cagtgaccag
    22021 attgaaatag taaagtttgc ttctagaaca tcagtcactt cacgaataga tgaaagactt
    22081 gcggctttac ttgtgtgtcc taaaatcatg aataaaaaga aagaaacaac aaatgccggg
    22141 acagttgacc acatcatatg cttgatgtgt ttgaacaaat cggcatcaac aatagctgct
    22201 gctagatttg ttgattcgga taatggagac atcttatctc caaaaacggc acctgaaaca
    22261 atagctccaa caaccagcgc tggatttaag cctagtgttg tcccaatacc gaaaaatgca
    22321 atcccaatcg ttgacataac agtaaaggca ctccctacag cgctacctac gattgcacac
    22381 acaacaaata cagaagggac aaaccactgg acactgatca atttgaaccc aatgaccatt
    22441 agagttggaa tgatccctgc ttgtatccat acagcaatca atgaaccgac taaaataaaa
    22501 ataaagattg ggatgattcc tggtttgatg ccattgatga ttccttcgtg cagccaatct
    22561 gtcgggtatc tttttatcac tgcatacaac atgaccattc cgatcgctgc taagatcgtg
    22621 atattaggtg agacctttaa tccgacaacg ccaatcgcaa tgcctaaaac aataaccatt
    22681 aatacaagtg ttgcttctaa aaaacttggt gttccttttt ttcccatgat aatctctcct
    22741 tttttagttg ttcttatgtt ctaaaaaagt taagatatcg gattactccg ccgcaattca
    22801 tccgcgattc ctcctttata aaaataaaaa gacctgtttt aaactaagga cgaatgactc
    22861 cgcggtacca ccttaattaa aaacagatct gtttttcact ttcaaacttt tattcaaatg
    22921 tatggacttt ccatgtaatt cgtcaattag gcttgatcgg ttcacagcga ccaccgactt
    22981 tctgaacaaa acacctaacc gctactgcgt gaaaagttga cttgtacgaa gtttaccttc
    23041 cataagatca tttgtcaatg aaaaagaaaa tattttttca tttttctgaa aattattttt
    23101 ataactttca cacacaagat tattttttac tagaaagtag cgccctcttg tttttttctt
    23161 gctactattt cttgatgttc ttgcttgatt ctttctaata gctttggctc tttcaacaga
    23221 tcaagagctg tattggcgag tagttctgct gcaatcgcaa tagaagcaag gcctttgtca
    23281 cttttagcag cagctttgaa ttcttctgtg tgtccggcaa tatatgtctc agagattgct
    23341 accgtaggct ggattgttgg tatgacttgg ctgacatttc ctacatcaga agaaccgaga
    23401 cttgttcttt gttccgtttc tatttcttca tctggaacac ctgcttcttt tgcatgctgg
    23461 aagaataagt catcaaaaga aggagtaacg atgacatcat caactgcatt ttggaacaat
    23521 ccaaactcaa aagtcgtgcc cgtacttatc gcagcacctc gtacgatatt ttccactttt
    23581 tcatatactt tatctaatgt ttgccgattt cctgcacgta aatagaaacg tccagcagcg
    23641 taatctggaa tgacgttggc agctactcct ccgtctgtaa tgatcccatg gatattgaca
    23701 tcttttggca attgcaagcg tagagcgttg attccattaa acacttggat caatgcttcc
    23761 aaagcattta ctcctttttc aggtgctgct gctgcatggg aagcgacacc gtaaaatttg
    23821 atgtcgactg gatcattcgc taaagattct gtcgttttcc cataacgaaa agctggatgg
    23881 acgcataacg ctacatcgac atcctcaaaa aaaccttctc gaacaaagct gcctttagct
    23941 gatccgttct cgcccccttc ttcccctggg gtgccatata cacggatttc tccaccagtt
    24001 tcatcaatga attgcttcac tatgctggcg gctaatacgg agtaagtacc aaacaaatta
    24061 tgcccgcatg catgaccaat acctggtaaa gcatcgaatt ctgccaaaaa ggcaattgtg
    24121 ggaccgggtt tattggaaat ataacgtgca tcaaaggctg ttcggtgtcc agctacttct
    24181 ttttctaccc aaaacctttc tttttctaat tgtttaatca acgctgctga ggaataaaac
    24241 tcatagttac ttacttcagg atgttcgtgg atatctagag caagtgcttg atattctggt
    24301 aaacgatatt ggattagatc cttcaattgg tttgttgaga ttgttgttgt cataaaaaat
    24361 tcctcctatg ctagtcattt ttcttatttt ctcccgaatg tttcccatgc aggcacgctt
    24421 gatccttttg atgttttctc gattactttg actgtgtctt ctgtttgata agcgtctact
    24481 attttttgat acgttttatt gttttcatct tcttttcttg caacgatgat attcacataa
    24541 ggacgtgcat ggtcatccac tggttctaag aagatggcat cagaagcagg attaaatcca
    24601 gcatctacag ctacaccgct attgatcact gaaatgtcta catctgacaa agcacgtgct
    24661 gtttgggaag catctaattc agaaatgtct agattttttc tattctcggt aatatcagaa
    24721 acagtgggcg cttgtccttt tgccttatcc actttgatca atccagcagt ttgcaataac
    24781 agaagagctc tgccgccatt tgtaacatca ttagggattg ctacttttgc tccgtctttg
    24841 atatcagcta catccttcaa agtgttagaa taaattccca gcggtgcatt gacagtattt
    24901 ccgatcgata ctaaatcagt tccgtgttct ttattgtaat tgtctaaaaa gaattgatgt
    24961 tggaaagaat tcaaatcaat cgatccatct gctaaagcca catttggttg attgtaatct
    25021 gtaaatttca cgtattccaa attaatgttc tcctttttca aacggtcttt cacgttgtcc
    25081 catacatctg tatcttctcc aataatccct agttttacga tagtttcttt tttgtcagtt
    25141 gtatctgctt ttccttggct acaccctgcc aaccaaataa ttgctacaaa tgtaatgact
    25201 acaaaacgaa taattttttt cattttttct cctccacttt caatgtgtaa tttttttaat
    25261 cagttgatta ctgataaatt gacttaaaaa aactaagatt agaatcaata atgtagccac
    25321 aatcgttaca tctgtttgga atcgattata ccctctcgat atagcaagat tccctaatcc
    25381 gcctgcacct actgctccag ccatggtagt cagtccgatc acgttgatga tagtcaacgc
    25441 cgagacccga atgataccag gcaaaccttc taacaaatac acacgtaaaa tgataccgat
    25501 tggactggtt cccatcgctt ctgccgcttc gatcacccca ggatcaactt ctagcagtgc
    25561 gttctcgatt tgacgagcaa aaaacggaac aactccaaaa atcaatggca ctaaagctgc
    25621 tttcgcacca atcgtcgttc caactaagaa acgagtagtc aatgctaaaa gagaaagcaa
    25681 gataatgaaa gggatggaac gaatgatatt gatcagctta tcaagtattt caaatagcag
    25741 acggttagct agtaatccat tagggcgtgt cactactaac gtcacaccta agatgattcc
    25801 aatcatcccg ccaatgaatg ctgtccaaaa agacatatat agtgtttgct tcgtcgcttc
    25861 gacaaattca tccggaatca aataaacatt gggcaaatat gttttaaaga aatcagtcat
    25921 tttatcttcc tccttcgatc actttgatac gactatctaa atcgtttttt tgtaaaatat
    25981 ttatttttac accagatttg atcaaataat ccaatgcttt tttccgctgt ttggtttctc
    26041 cagctaaagt aacgatcaaa ctccctaacg gcgtttcttg taataactct acattgccat
    26101 ataaaatatt cgctgttact tgatatttgc tgtacagatg agcgattaga ggttcgttcg
    26161 tctgatttcc aatataactt aattccacca gccatttatt ggcgatctga tcggcaaaag
    26221 cagaatgggc aatgatcgtt tctaatgctt ggtcaagatg agtagctgtt cgaataaaat
    26281 ctttggtcaa ttcttcttca ggattgctga agatctggat gctgctacct ttttcaacga
    26341 ttcttccatc ttccataacc gctaccttgt tgcagatttc tttgacaact tgcatctcat
    26401 gagtgatcag gacgattgtt aaacctaact ggcgattcaa tttttttaac aatgcaagga
    26461 tctgaagggt cgttttcgga tcaagtgcac tggttgcttc atcacataat aataccttag
    26521 gttcattcgc caaagctcgt gcgattgcta ctcgttgttt ttgtcccccc gacagttgtt
    26581 taggataagc agatgctttt tcttccaaac cgacaagttc cagtagttca ttcacttttt
    26641 gacgacgttc ctgtttcgat tttccagaat actttaaaga aaaatcaacg ttgtcaaaaa
    26701 tagttcggct ttccattaga ttgaaatgct gaaagatcat accgatggcc tttctttctt
    26761 ttcgcaattc tttgggagag agctgactca gattcgtctg attgacaatg acttctcctg
    26821 ctgttggttt ctgcagcaaa ttcatcacac gaactaacgt acttttccct gcacctgagt
    26881 aaccgacgat tccataaaca tcgccttttt caatcgttaa atctacagaa tctactgcct
    26941 gtatctcttt ttctttttgt ttgaaacata cagaaacatc tcgcaattca atcattaaaa
    27001 ttcctcctta tctaaaaaaa gcgtcctcaa gaaaatgaaa atgtcatttt cttgaggacg
    27061 cttttttgcg tgttaccacc tcatgttcaa gctgtgttca cacacaactc ctcttcaagt
    27121 acgatcatac tctagcaaga tatcggtcgc agccgtcatc gccttacatc tatgctcggg
    27181 atgaattgct cgatggccat tttccaatag tcgttccttg cttcttctca gctaccgaag
    27241 ctctctgtca aaggttcttc tatcgtactt accatttcaa tgcaaataat attcaaaaaa
    27301 aaagtccttt tactaacata aactatgtca gtaaaaggac gacgtatcgc ggtaccacct
    27361 tttttcggaa gtttccttcc ctcaagccca acatctcaaa aagagagatt ggcgttcgtt
    27421 ttaacggtcg aacagttccg aatttgccta cttatcgaca aattattctc caaggccatt
    27481 ttcagctttt cttacttgac tcttctcacc agccagagcc tctctgcaaa gtttccaaac
    27541 ttactttcct tttcaacgaa atcgatattt tgttgttggg attaatctac atgaggaaaa
    27601 ctgaaaagtc aagtacgaaa ttcaaattat tttttctata tttatttttc tgttttttta
    27661 tttaacattt caataacagt tcgaagatct tttccttccg caagaagttt caatttttcc
    27721 ttttcttcga cggtataatt tcggacaaaa ctggaatcag gtatcaaaac aacgcctaat
    27781 cctgctcgtg aagcagctgt tgctcctact aaagaatctt ccactgcaaa ggctgaacta
    27841 gcttctaatc ctgttcgttc caaagctgtc agataaggaa tcggtgaagg cttgttctcc
    27901 gacacttcgt ctccgaatgt aaacgtgtcc aagtaatcag ctaatttaaa gtgatccaag
    27961 atatctgttg ctcttttcgt aacagtggtc gtagcaatgc ctagtttcat atgacgttct
    28021 tttaagtctg ccaatatttc ttttgcatat ggttttaagt ggatggctcc gcttgtcagc
    28081 tgttgataaa aatattcttc acgcttcgct cggacttcct gtactttttc agggctacct
    28141 gctgctttca ctaaaatatc aaaactttgt ttccagtttt ttccgcccca agcgtcaacg
    28201 atttcttttg ggatatggat atcaaattgc tgaaatcccc aaagccagcc atcacgatac
    28261 gttttttctg tgtcaactaa caaaccatct aaatcaaata ttgcaccttt catctataca
    28321 ttaatccttt ccaaaacaat acacatagtt tagcacgact ggtccaaaaa gaacagaagc
    28381 aaagaaccag ccttctcgtt tataagagtt cttggaatcg acggatatag attttcttca
    28441 cagctgtcac aagcgccaga taagcgatga ctgtagcaaa taaccataac cagtaattgc
    28501 caggaagtgg catcaagcct aattcagcac caaaacttgt aaaaggaagg acagaaccga
    28561 caataattcc taatgtagtg ataacaaaca tggcaaatgt tgcgttgctt tggataaatg
    28621 gtactttcgg tgtacgcagt gcatggagca ctaaggtttg tgtccatagt gattcgacaa
    28681 accatcctgc atggaataat gcgatgaaaa tcactcgctg tgaactatcc aatgtatgga
    28741 aacttccgcc cactacagca ggacaaataa caaaatacat caacaagtaa gtagtaatat
    28801 caaatatcga acttgttgga ccaaagtaaa ccatgaattc cccaatacta gatgcattcc
    28861 atttttttgg ctcgtccaaa tattctttat ccatccgatc ccatggcaag gaaatgcagg
    28921 aaacatcata gatcagattc aaaaacaaaa gttgtaaagg cagcattggt aaaaatggca
    28981 ggaacgtact tgcaatcagc acggaaaaca tattgccaaa attagaactt gctgtagcct
    29041 tgatatattt catgatattc ccaaaagttt ctcgtccaga aagaaggcct ctttccaaaa
    29101 tcgtcaaatc tttttctaaa aggatcacgt ctgcagattc tttcgcaata tccacagctg
    29161 tatctacaga aataccgata tcagccactt tcattgcagg agcgtcattg ataccatctc
    29221 ctaaaaatcc gacagtatga ccatttttac gtaaagctgt cgtcaaacgt gctttttgct
    29281 gaggattcaa ttttacgaat acttcatggt cttcagctac ttgtgctaat tcatgatcac
    29341 tcatttccga gattttctca ccggtaacca attcattgat ctctagacct acttgacggc
    29401 acactgaacg tgtaactaat tcgttgtccc cagtcagaac ttttacagct acaccatgtt
    29461 ctttcagagc tttcaacgct tgtttcgttg tttcttttgg tggatcaagg aaagcaagat
    29521 aaccaatcaa aaccatgtct gactcatctt tgactgaaaa ttctccaacg acgcttggat
    29581 tggtcttttg tgcgacacca atcactcgta agccatcttc attaagtgac tgtacttttg
    29641 caagtacggc ttcttttcgt tcttttgtta atggtgtaac agtaccgcca agatcaataa
    29701 atttagaaat gttcagcatt tcttcaatcg caccttttgt gatcatttgt gttttaccag
    29761 ctggatcagc aaccacaaca ctcatacgac gacgttcaaa atcaaaagga atttcatcca
    29821 ctttttgata attgatctta tctgtatcta aagtttctgt tgcttcatca atgatagcca
    29881 catctaacaa atttttcagc cctgtttgat agtagctatt tagatacgca tggcgcaaaa
    29941 cacgatcatc ttcatttcct tcacaatcca tatgatattc aagaatgatt ttatcttgtg
    30001 tcaatgtccc cgttttatcc gtacataaca catcgattgc accaaagttc tggatggcat
    30061 tcaaattttt gatcactgtt ccttttttgg ccatcacact tgctcctttg accaaattcg
    30121 tcgtaacgat cattggaagc atttcaggtg ttagaccaac tgctacagat agtccaaaaa
    30181 gaaaagcttc tagccaatcc ccttttgtaa gcccattgat gacgataact gctggagcca
    30241 tcaatgacat aaatttgatc agtagcatgg atgttttatg gatgcctaat tcaaagcttg
    30301 attgaattgg tttttcagat agcgtttctg ctacatgacc aaatagtgtt tcatttccaa
    30361 cagaaacaat gattccttcc gcacttccac tgatgacatt acttcccata aagacaagat
    30421 tttcgtaact tgtttcgctt tgctgatcgt cttcacatac tttcgcatgc ttttctactg
    30481 gatagctttc ccctgtcaat gctgcttggg aaatgaataa atcctttgcg gacaataaac
    30541 gcatatccgc tggtatcata tcccctgctg aaagccgaac aagatctcca cagacgattt
    30601 cttccatagg aatctctgtg tactttccat tacgttttac agctgccgtt actttcacaa
    30661 gtgatttcag tttttcagcc gcttgattgg aacgtacgga ctgaatcaac gtcattgtcc
    30721 cgctgacgat aaccatagtg aagataatgg ctacaccgaa aagatcttta tctccaggag
    30781 ctgctaatac atattccgtg atgaatgaaa taattcctaa tgcgatcaac actaatgtaa
    30841 atggcgtgat gtatgctttc aatatttcta caatgaatgg tgtttttttg ccatatgaaa
    30901 tcgcattttc accgtaattt tctcttgaac gttcgatttg ttcttctgtc aatccatttg
    30961 ctgatgcatg gaatagttca aataattctt gtttcgtttt tccagcaaaa gctgcataga
    31021 ttttttgtgt atctttcttt ttttccatct caatctctcc tttgtgtcca aaagacagct
    31081 gttctcgctg cttttggtct ttagctattc atcggatcga tagagaaaaa actgaaaggg
    31141 gctgagaaca gatagataat agccctggcc tttcctctag atccttgttt ttcgaatgac
    31201 tgtcatccat ttgttctcat ctcctttact aagtaatttt aattcatgac ttccaatcat
    31261 ttttcgaata gttatttttc caattagacc acctcctttt tatttttcac cgatggggat
    31321 ttgcggcaac aaaaaaacct ctcgccaaat actcagcgaa aggtttgaaa aagcatatta
    31381 aaaaaagctt ctcagatctc atcgttgagt tttgacactg tacaacgtaa aaagcagata
    31441 cctgctttta gctaccttat gaaaagcctt atctcgacaa ttcctgttct acccattggc
    31501 gtctctcgac gtttttgggc agtagcctat gtttgtatag gagcctcacc taacaaatct
    31561 tattcggttt tccttcgtta atataacaac taaaaaagag gatgtcaaat caattttcca
    31621 tgtttttcat acttttttta aaatacacac gttatattcc tgtctcacgc ggttttattt
    31681 gtctcatttt ccacctcccg ctataataga aatatagtag gaaacgaggt gctgttatgg
    31741 aaagaacact tgttattatc aagccagacg gcgtgagacg ccatttagtc ggaagcatca
    31801 tccaacgttt tgaagcaaag ggactggcca ttgctgaaat gaagtttgaa actatgactc
    31861 ctgaattagc aaaagaacat tatcagcact tgactgagcg cagttttttt gatgaactga
    31921 tcgattacat gacttccggt cctgtcgttt atcttgtgct ggtcggcgag gaagtgatcg
    31981 atatcgtccg taagatggtt ggagcaacaa aagctgccga tgctgttcca ggtacgatcc
    32041 gaggagacta cgcgctgccg gggactgaaa acatcattca cgcttctgat tcccgtgatg
    32101 ctgcggtaaa agagatcgcc cgctttttcc cgccattcga tataaacaaa ccgtctgaaa
    32161 aagcggcgaa gtgatacaaa ttctaaactg ctggtctagt tgctgggttc agcaatggcc
    32221 agcagttttt tctctaagga cctccgttga ttctttccta acatatattc gagcactgtg
    32281 aagaattctt ggtagtcttt cgtcttttct tcccctaaag cagcagaaat caatctttga
    32341 taataatctg ccatcaatgt ttcatagatc actgtacttc tttctttatg tgctaagctc
    32401 cgtttcatat cttcattcac actacgtgcc tttttcaacc gaccattttc tatataaaac
    32461 gaagtcaggt tcattaaaaa agtaaagaga tactgctcat gattgttcaa ctgtgctaat
    32521 cgtcgcattc tttttttgat tttcaaataa ttgttctcaa tgaaccgatc actgaatatc
    32581 caaggaaaat cagctagaat agatagttca aattgaccat agtctggtat ctgcatcaag
    32641 tattcttcaa tgattcggca ttcataacgt aaaaattcaa attctgtctc agatacttct
    32701 gttttttcga ccatgtgaag attcaaaacc aaataataca gatcttctgt tttcttaaaa
    32761 tgcctacggt tattgctgat ctctttataa ggatcaaagc tgtcttcttg tacccgatct
    32821 agcattcgtc tttttttctt taactttatt ggttcatcca gctggtttcg catccattca
    32881 tattctgcaa gtgtcatgtt cattcgctct aaaaatgatc tcaatgttac aaatgacatt
    32941 tttttcactg aatttgtctc aatcccgact agagaagtct taaaacagat tccttccgct
    33001 aattgggact gtgtcaactt cttgttgact cgaagtttct tgatcaattc accatcatac
    33061 ataatagttc tcctttttaa tttaaatttt tccacattca ataaatagat acgttaaaaa
    33121 ggaaaaatac acgaaaaaaa taaaaaaatg tttttttcat aaaaaatacc aaccttcaag
    33181 cattagaatg ttgtctaact actgaaggtt ggtttgattg tttattgatt atttttttgc
    33241 tgttcaacgt ctgttcttgt tactggatat aagttggttg ttgttttatt accatttttt
    33301 gaaaagacac ttgtcgaatg ttcgcctttt tgcttttcga ttgcttcatt acgttccgct
    33361 tcatttttat agtcatattt tttcggatca atcgtctcaa atccgtttgg cacataaaac
    33421 cgcaagagat tttcctgatt cagcttatct gaaagactta acgcagtctt gactttttcc
    33481 tgatctttgg agatttcctc atcgattcct gctgctttcg tatcgatgat ttctcctgtc
    33541 tgattattgt aagcttttcc tcctaggacg gtgtatttgg gtgtcacaaa gttcccattt
    33601 cgaaaagcaa ctacttgatc atgctgagaa gataataagt ctgtaccaaa atgaagataa
    33661 tctttatcat cgattcccaa tagatgtagt aatgtcggca aaacatcgat ttctccaccg
    33721 tattcatgat tgactgtccc tttagtataa ccaggcatat ggatcatcaa tggcactcgt
    33781 tgcatctgtg cgttgtcaaa ttcatcccat gtatctggat ctttaccaag agcgcttgct
    33841 aaatctttat tatctgtatt cgagatccca aaatgatccc cgtaaatcac aaagattgaa
    33901 ttttggtaaa taccagattt tttcaaatac gtaaaaaatt gttccaatga ttgatccaga
    33961 taatgtgccg ttcgaacata attatctact gtgctattgc cagtattcaa agatggaaag
    34021 tcgaaattct tgtcatccgt ataataaggc gtgtggttgg ttacggaaag aaatttcgtg
    34081 taaaacggct gttgtagatg ctcaagatat tgggcagatt ctctgaataa atctttatct
    34141 aatatcccat aacctaacgt ttcgtcggat tcatcaaaat aagatcgatc aaagaaattg
    34201 tcataaccta agtttttata tacatgatct ctattccaaa aactagctac attcccatgg
    34261 aaaacagcgc ttgtatagcc ttgcttttgt ccaaggatcg ctggtgcggc ttgaaagaca
    34321 ttgtctgacc caagttctgt gaataatgag ccttgaggta aaccaaatgt gccagtttcc
    34381 aacatatttt cagcatcact tgtctttccc tgtcctactt catgaaagaa attgtcaaag
    34441 ctgatcgttg cttgattctg gaaaatacta tttaaaaacg gtgtgacttc ttgtccgtct
    34501 accttcatat taatcaaaaa ctgctggaaa ctttctaaat ggagaacgat cacatttttc
    34561 cctttagcga tcccaaatgt ttcgggattt ggctctgcat aatgtttctt tgtataatct
    34621 aaaacttcat caatcccatt actgcttgca tgcgcgcgaa cactgctagt cattcctgtt
    34681 ttgattccgt cataaatagt atacgcatcg attcctagat atttgacaat atatgaacgg
    34741 tcaaatgttc gctgcagcaa ttgtggacgg ttggcttcgc tcagcgctag atttcctgaa
    34801 aaaataagcc ctgaaagaca ggtaacagcg atagccatcg gtttgccgac agggttgctt
    34861 ttgataggta ttttcttgac cttcaaccaa accagtagcc caatgaacac agcgatatcc
    34921 agccagtaga tgacatcatg gggcttcatc aaagaaaagg agcttcctga caatccttgc
    34981 gacactttcg aaaagcctaa tacagatttg actgtaatga aatctgtgaa ttcccgataa
    35041 aaaataatat tcaagtacaa caaaagcgta tttaaaatat caatgatcaa aagaatagct
    35101 aacgctggct ttggcttttt aatatacaaa gaaaggccaa aaaacaataa ggtagtcgca
    35161 attgggttga tccacaagat aaagtactgg atcgtacctt ccacacctaa tgaaaaatct
    35221 gcatagtagg caatgatcgt cttcagccag aaaaagaaaa cagctgtcaa aacgattgct
    35281 aaacgatttt ggcacaattt tttaagttgt gtcacgtata tcacttctct ctattcacat
    35341 tttttcttat tttgctcctg aaaaatgaaa atttcctaaa aaagttgtta tcttaagatt
    35401 tttttattct ttctaaagat tattccgtcc acttttcaca gcataaaacc gctgcgatgt
    35461 aagcgattaa actaatgaag agataaaagt cttgtggtga ccgcttcact ccacggtatt
    35521 caaaagccag tttctcggta ttcgtacaaa aaaagaggct gtgacaaaat tcttgtcgca
    35581 gctccttatt tcttgatgca ggacagcttt ttcacaactt cttccttaaa cggtgttctc
    35641 ctgccaactc ctcggccaca agtcacaata tttataaaac atgagaagct gttttttgaa
    35701 attgttcctt gtggctcaga gttaaacggc aggctcaaga cctcttgata cacggtgttc
    35761 aatcagctga ccctcggtat tagattatgt caggacgcta attttacaac ctcttggtaa
    35821 acggtgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa atataaggag
    35881 ctattttttg aaattgctcc ttgtggctca gagttaaacg gcaggctcaa gacctcttga
    35941 ta
//
LOCUS       DBBGRF010000027        35883 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000027 DBBGRF010000000
VERSION     DBBGRF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.027"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..1152
                     /locus_tag="ACIZD4_001512"
     CDS             <1..1152
                     /locus_tag="ACIZD4_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HGC5990453.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="ACIZD4_001513"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="ACIZD4_001513"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGC5990454.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="ACIZD4_001514"
     CDS             2728..3003
                     /locus_tag="ACIZD4_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGC5990455.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="ACIZD4_001515"
     CDS             3009..3776
                     /locus_tag="ACIZD4_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGC5990456.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="ACIZD4_001516"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="ACIZD4_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGC5990457.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="ACIZD4_001517"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="ACIZD4_001517"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HGC5990458.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="ACIZD4_001518"
     CDS             7920..8222
                     /locus_tag="ACIZD4_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HGC5990459.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="ACIZD4_001519"
     CDS             8225..9388
                     /locus_tag="ACIZD4_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGC5990460.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="ACIZD4_001520"
     CDS             9414..12842
                     /locus_tag="ACIZD4_001520"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HGC5990461.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="ACIZD4_001521"
     CDS             12863..13987
                     /locus_tag="ACIZD4_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HGC5990462.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13968..14414
                     /locus_tag="ACIZD4_001522"
     CDS             13968..14414
                     /locus_tag="ACIZD4_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HGC5990463.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="ACIZD4_001523"
     CDS             14398..14736
                     /locus_tag="ACIZD4_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGC5990464.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="ACIZD4_001524"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="ACIZD4_001524"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGC5990465.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="ACIZD4_001525"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="ACIZD4_001525"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGC5990466.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="ACIZD4_001526"
     CDS             15893..16936
                     /locus_tag="ACIZD4_001526"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGC5990467.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="ACIZD4_001527"
     CDS             17095..17823
                     /locus_tag="ACIZD4_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGC5990468.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="ACIZD4_001528"
     CDS             17939..18184
                     /locus_tag="ACIZD4_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGC5990469.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="ACIZD4_001529"
     CDS             18181..18399
                     /locus_tag="ACIZD4_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HGC5990470.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="ACIZD4_001530"
     CDS             18535..19074
                     /locus_tag="ACIZD4_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HGC5990471.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="ACIZD4_001531"
     CDS             19067..21340
                     /locus_tag="ACIZD4_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGC5990472.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="ACIZD4_001532"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="ACIZD4_001532"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGC5990473.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /gene="rpsT"
                     /locus_tag="ACIZD4_001533"
     CDS             complement(22513..22767)
                     /gene="rpsT"
                     /locus_tag="ACIZD4_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGC5990474.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="ACIZD4_001534"
     CDS             complement(23167..23436)
                     /locus_tag="ACIZD4_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990475.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23698..23826)
                     /locus_tag="ACIZD4_001535"
     CDS             complement(23698..23826)
                     /locus_tag="ACIZD4_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990476.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(23906..24361)
                     /locus_tag="ACIZD4_001536"
     CDS             complement(23906..24361)
                     /locus_tag="ACIZD4_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HGC5990477.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="ACIZD4_001537"
     CDS             complement(24499..26427)
                     /locus_tag="ACIZD4_001537"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC5990478.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="ACIZD4_001538"
     CDS             complement(26624..27457)
                     /locus_tag="ACIZD4_001538"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGC5990479.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="ACIZD4_001539"
     CDS             complement(27649..28353)
                     /locus_tag="ACIZD4_001539"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC5990480.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="ACIZD4_001540"
     CDS             complement(28376..29002)
                     /locus_tag="ACIZD4_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGC5990481.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31704
                     /locus_tag="ACIZD4_001541"
                     /pseudo
     CDS             29328..31704
                     /locus_tag="ACIZD4_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
     gene            complement(31728..32219)
                     /locus_tag="ACIZD4_001542"
     CDS             complement(31728..32219)
                     /locus_tag="ACIZD4_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HGC5990482.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32406..33326
                     /locus_tag="ACIZD4_001543"
     CDS             32406..33326
                     /locus_tag="ACIZD4_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC5990483.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33480..33824
                     /locus_tag="ACIZD4_001544"
     CDS             33480..33824
                     /locus_tag="ACIZD4_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGC5990484.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34014..34514)
                     /locus_tag="ACIZD4_001545"
     CDS             complement(34014..34514)
                     /locus_tag="ACIZD4_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5990485.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35042..35125
                     /locus_tag="ACIZD4_001546"
     tRNA            35042..35125
                     /locus_tag="ACIZD4_001546"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35076..35078,aa:Leu,seq:cag)
     gene            complement(35449..>35883)
                     /locus_tag="ACIZD4_001547"
     CDS             complement(35449..>35883)
                     /locus_tag="ACIZD4_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HGC5990486.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11869 a         6262 c         7405 g        10347 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttatttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact gggggggaca aaaaagtctg gcttacaaac tgccgagtcc tttcccagaa
    31021 ggaaaccagc aagttttcat cgcaaattac ctagagacga cttatcgaaa aagggaacac
    31081 agtctggcaa aattagtaga gacgattcat gcttttgctg atggaaaggt cgggaattat
    31141 ttcgttttct ttccttctta tcaatattta gatcttgcgg tggaagcatt cagacagcaa
    31201 tatcccgaca gcaatgtgct aatccaagaa acggacatga atgaggaaga acgcgaacga
    31261 tttttaacaa aatttcaaac aaatcccgct gaaacattga ttggattttg cgtacttggc
    31321 gggatttttt cagaaggaat cgatttgaga ggggaccgat tgatcggcag tatgatcgta
    31381 ggtgtaggtt tgccgcagat gaatcatgag caggaactga tcaaatcata ttatgatgag
    31441 aaggaacacc ttggatttgc ttacgcttat cagcttcctg gaatgaacaa agtcttgcaa
    31501 gctggtggtc gagtgattcg tggcatggcg gatcaaggaa tcgttgtatt ggcagatcaa
    31561 cgattttcta gtttttctta tcgacgttta ttcccacaac attggcaaac agcaagagaa
    31621 gtacgaagtg ttggggaatt ggaagaagga atacagcgtt tttggttatc aaaagaagca
    31681 gtaaatcaaa aaaacgagga atgacagacg tcagcctcgt tttttgatta acgatagtta
    31741 gtgaattgca actcgattgg taagtcaagt ttacgtaata aagcaatcac agcttgtaga
    31801 tcatcacggt tcttacctgt cactctaatc tgatcttctt ggatttgtgc ttttactttc
    31861 agtttttcat ttttgatagc tgtagtgatt ttcttcgcgt tttcacgatc gattccgttg
    31921 accaaatcgg cagtttgtcg agctttgcca cctagagcgt gttctgattc ggaaaaatgg
    31981 atatttttga ttggcacatt tcttttgatc agcttaccaa ataatacatc tttgatctgt
    32041 tcgattttga aatcatcatc gctcaataca actagattgc tgttctctaa tttgatttct
    32101 actgtagaat ccttgaagtc aaagcgattg gacaattctt ttgttgtttg ctgaatcgca
    32161 ttttttactt cttctgtatt gacttctgat acaatgtcga agctagcatc ttttgccata
    32221 ggaaccctcc tgatatacat ataaatattt accatacatc tatcttatca taggattagg
    32281 gcagattctt acctgtttgc taaaattctt ctcatttgag ttcgaagtat tttattttaa
    32341 tagataaact gttattctta catttggaat accaaagtag gggagaggtg cttgtgagta
    32401 aaattatgac tgcgtatcat aaaaatgaaa gattaaagaa aatagtggtt attttgataa
    32461 ccggattgac cgctgcggtc gctttaaatt attttttgat tccagccaat gtcttttctg
    32521 cagggatgaa tgggatcgct caaatcattt cctcgctttt atatgaatgg tttcatatca
    32581 agatagacac aggaacattt atttttcttt tgaatatccc tgtgtttgta ttagggtttc
    32641 tcaaagtagg aaaacgagca acgatcctta gttttgtgaa tgttgtatgt gtatcggtga
    32701 tgacgatgct gcttccagtc ggacagatca ctgataatat tttgatgaat gccctagtag
    32761 gcggtgtttt attaggtctt ggcgtaggat tatctttaaa aatgggcttt acaactggtg
    32821 ggatggatat catctctctt gtactttcac aaacaactgg aaaaacagtc ggaaactaca
    32881 tgctgattct aaatggtatc attgtagtca tcgcaggctt cttctttaac tgggaaagtg
    32941 ccttgtatac gattatttcc atttatgcaa tgactcaagt aattgatgcc atccacacga
    33001 gtcatcaaaa agtaacagca atgatcgtta ccgtcaagcc agaagaggta acagaagaac
    33061 tagcaaaacg gatggtacgt ggaatgacat tactgccgtc tgtcggtggc tattcaaaaa
    33121 aacaagggaa catgatcatg atggtcatca cccgctacga aatgtatgat cttgatcaga
    33181 tcgttcatga aatcgacgac gatgcattta tcaatatttt accaactcat tcagtatttg
    33241 gccggtttgc aaatgaaaac gaacaaaaaa tgtatcgaac aactggcgta ttgccagaaa
    33301 taaaaaatcg ttcacaaaaa aaatgaggaa tcaggtttat tttagaataa atttaatcta
    33361 ttacatctaa taagaacatt tttataaatt taaacgagaa tcttacttct aaattctcat
    33421 ttacaagcag ctaaaaaaag agtatgataa ataaaaatcg tgttaaggag tgtcgtacga
    33481 tgagcgaagc aaaccaagaa cggtctggac aagaaataga actaatcaaa gaacgtattc
    33541 ttgctgcctt ggaaatggtg attgatcctg aattaggaat cgacatcgtc aatttaggct
    33601 tgatttatga tatagaattc aatcctgaaa atggagaaac agtcattaag atgactctaa
    33661 caactatggg ctgtccatta gcagatattt taacagaatc tatccatgac gcattaaaag
    33721 aagtgccaga agtaacgaaa gcagaagtca aactagtctg gtatccagca tggacgacag
    33781 ataagatgag ccgttatgca cggattgcgt tggggatacg atagaaatct tggctgacta
    33841 gctatgagaa gcaaatagga aaaacaaaaa agccttttat cctttctaga agaaaagaga
    33901 taaaaggttt ctttgtttat aaaattttgt ctgctatatt ataagttaat taaataaatg
    33961 tgttctattg ataaaggaca ttcaaatccc tttccttttg gaatccttct tttttacatc
    34021 agtttgattt tcgtatagta ttctttctca tcttcacgat aaatcgcagc cccatttttt
    34081 tgttgtgctt taagactgcc aagatttttt ttatttacag acaaaagtgc ctcatcaatg
    34141 ccgatttttt ttgcctcttg tagtactaat gctaatcctt gtgtggcata tcctttttta
    34201 cgataattag gggagatgcc gtaaccaata tggccagcgc cgtttcttaa tgtttcgttc
    34261 agtttatggc gcaaattaaa aattcctaca tactcatgtt catcactttc taaaataaag
    34321 acggttgcgg gaacgtaact ctcaggaaga tcgattccta aagacgtttt ttcgcatttt
    34381 tttacataat ctaaaaattc agcaaatgta tagccataag cattgttgat aaatccactc
    34441 tcatttggtc caaagctagt ttgtagctga taagctttct ttaaatctgc ttcccatagt
    34501 ttgatcagtt tcatcgtatt cacctcttta agtaacctta ttcatttgtt ttctactata
    34561 gcactattgt tgtaaatagc catgcctatt tttatttatt gtgtcatatc gtattaagaa
    34621 tcatcgaaca atacaaatat gaattacaat aaaaaaatta tttgaagttc gttcattcgt
    34681 tacttatgat ctctagaaga aagaaaacgt gaattacttc agcgtctaga attccagaag
    34741 gatagtaatc aacagaagaa ataatcaata tccaaatgaa agaagatagc tgaatcgaga
    34801 aaaagaggaa aaaagaaatg aagaaaaaaa taaaatagtt actaatccca gagtcgttcg
    34861 tttaacattg aaatcgatca tatggataaa acagattttt tcaccaaccc tcaatagatg
    34921 atggagttgc tcggatgaat tatttgtgta gatggcataa gggagggcgt acagaaatga
    34981 aaaagaacaa aaatatgttc ttgacaaaaa acacatgtaa tcctaaacta aaagatgtga
    35041 tgcggctatg gcggaattgg cagacgcgct agcttcaggc gctagtgagg gtgacctcgt
    35101 ggaagttcga gtcttcttag ccgcataatt tgttttttta taaagagaag gtacacctgg
    35161 agcgatgaga aagaaaataa catattatct aaaagaatat aggaaaaatt ttaaacaacg
    35221 gaaccagatt caaataaatc aaaaaaaatt tgtgtgaagg tgggacagtt taaaacctaa
    35281 tagattgatt caaatagtag atttatagat tctgatacaa gaaatactgg caaacgatag
    35341 ttaaggaata aagactaaac ttaaactcaa aaagaggtca tgcgaaagaa taaatcgcat
    35401 gacctcttac tatattttga atgtgtttaa acgttcaaat aatgaatctt agtaccaacc
    35461 gtttgcttcc cagaatgctt tcgccgcttc ccaagaacca taacgtgaag taacatattg
    35521 ttctgctact ctttcttggt ttgcagcaga gtagtcacca tttaagtaag aagaatctaa
    35581 ttggtaacgg ccgatgtaac gtccgttcgt tgctgtgtaa gaaccgcttg attctttttg
    35641 tgcgatccat tcttttgcag agcttgtact tgctggagta gcagcagttt ctgttacagc
    35701 aggagcaggt tgtgtttcag caacaggcgc tgcttgtgtt tccgtttgaa ccgtttcttg
    35761 tacaacaggt tgttcagctt gaacaggttc agcttggact ggtgcttctt gaacggctgc
    35821 ttgaggttca gcagctgctt gtgcagagcc ttctgttggg attgttaatt gttgtcctga
    35881 gta
//
LOCUS       DBBGRF010000028        35246 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000028 DBBGRF010000000
VERSION     DBBGRF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.028"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            139..570
                     /gene="mraZ"
                     /locus_tag="ACIZD4_001548"
     CDS             139..570
                     /gene="mraZ"
                     /locus_tag="ACIZD4_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HGC5990487.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            591..1550
                     /gene="rsmH"
                     /locus_tag="ACIZD4_001549"
     CDS             591..1550
                     /gene="rsmH"
                     /locus_tag="ACIZD4_001549"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGC5990488.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            1555..1956
                     /gene="ftsL"
                     /locus_tag="ACIZD4_001550"
     CDS             1555..1956
                     /gene="ftsL"
                     /locus_tag="ACIZD4_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGC5990489.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            1957..4149
                     /locus_tag="ACIZD4_001551"
     CDS             1957..4149
                     /locus_tag="ACIZD4_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HGC5990490.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            4175..5137
                     /gene="mraY"
                     /locus_tag="ACIZD4_001552"
     CDS             4175..5137
                     /gene="mraY"
                     /locus_tag="ACIZD4_001552"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGC5990491.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            5151..6512
                     /gene="murD"
                     /locus_tag="ACIZD4_001553"
     CDS             5151..6512
                     /gene="murD"
                     /locus_tag="ACIZD4_001553"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGC5990492.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            6538..7626
                     /gene="murG"
                     /locus_tag="ACIZD4_001554"
     CDS             6538..7626
                     /gene="murG"
                     /locus_tag="ACIZD4_001554"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HGC5990493.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            7641..8861
                     /locus_tag="ACIZD4_001555"
     CDS             7641..8861
                     /locus_tag="ACIZD4_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HGC5990494.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            9017..10342
                     /gene="ftsA"
                     /locus_tag="ACIZD4_001556"
     CDS             9017..10342
                     /gene="ftsA"
                     /locus_tag="ACIZD4_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGC5990495.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            10365..11606
                     /gene="ftsZ"
                     /locus_tag="ACIZD4_001557"
     CDS             10365..11606
                     /gene="ftsZ"
                     /locus_tag="ACIZD4_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGC5990496.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            11623..12300
                     /locus_tag="ACIZD4_001558"
     CDS             11623..12300
                     /locus_tag="ACIZD4_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGC5990497.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            12314..12913
                     /locus_tag="ACIZD4_001559"
     CDS             12314..12913
                     /locus_tag="ACIZD4_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGC5990498.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            12994..13215
                     /locus_tag="ACIZD4_001560"
     CDS             12994..13215
                     /locus_tag="ACIZD4_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGC5990499.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            13264..14046
                     /locus_tag="ACIZD4_001561"
     CDS             13264..14046
                     /locus_tag="ACIZD4_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGC5990500.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            14067..14774
                     /locus_tag="ACIZD4_001562"
     CDS             14067..14774
                     /locus_tag="ACIZD4_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HGC5990501.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            15036..17834
                     /gene="ileS"
                     /locus_tag="ACIZD4_001563"
     CDS             15036..17834
                     /gene="ileS"
                     /locus_tag="ACIZD4_001563"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGC5990502.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(17883..19409)
                     /gene="zwf"
                     /locus_tag="ACIZD4_001564"
     CDS             complement(17883..19409)
                     /gene="zwf"
                     /locus_tag="ACIZD4_001564"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGC5990503.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(19424..20071)
                     /locus_tag="ACIZD4_001565"
     CDS             complement(19424..20071)
                     /locus_tag="ACIZD4_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGC5990504.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(20255..20584)
                     /locus_tag="ACIZD4_001566"
     CDS             complement(20255..20584)
                     /locus_tag="ACIZD4_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HGC5990505.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            20761..21489
                     /gene="sfsA"
                     /locus_tag="ACIZD4_001567"
     CDS             20761..21489
                     /gene="sfsA"
                     /locus_tag="ACIZD4_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HGC5990506.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            21505..22518
                     /locus_tag="ACIZD4_001568"
     CDS             21505..22518
                     /locus_tag="ACIZD4_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC5990507.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            22518..23795
                     /locus_tag="ACIZD4_001569"
     CDS             22518..23795
                     /locus_tag="ACIZD4_001569"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC5990508.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            23858..26560
                     /locus_tag="ACIZD4_001570"
     CDS             23858..26560
                     /locus_tag="ACIZD4_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC5990509.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYDQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            26712..27029
                     /locus_tag="ACIZD4_001571"
     CDS             26712..27029
                     /locus_tag="ACIZD4_001571"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC5990510.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            27059..27379
                     /locus_tag="ACIZD4_001572"
     CDS             27059..27379
                     /locus_tag="ACIZD4_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGC5990511.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            27487..28947
                     /locus_tag="ACIZD4_001573"
     CDS             27487..28947
                     /locus_tag="ACIZD4_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC5990512.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            29015..29236
                     /locus_tag="ACIZD4_001574"
     CDS             29015..29236
                     /locus_tag="ACIZD4_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990513.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            29267..29449
                     /locus_tag="ACIZD4_001575"
     CDS             29267..29449
                     /locus_tag="ACIZD4_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HGC5990514.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            29449..29862
                     /locus_tag="ACIZD4_001576"
     CDS             29449..29862
                     /locus_tag="ACIZD4_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HGC5990515.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            29985..31166
                     /gene="eis"
                     /locus_tag="ACIZD4_001577"
     CDS             29985..31166
                     /gene="eis"
                     /locus_tag="ACIZD4_001577"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced intracellular survival protein Eis"
                     /protein_id="HGC5990516.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMAPPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(31237..31401)
                     /locus_tag="ACIZD4_001578"
     CDS             complement(31237..31401)
                     /locus_tag="ACIZD4_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990517.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            31555..31628
                     /locus_tag="ACIZD4_001579"
     tRNA            31555..31628
                     /locus_tag="ACIZD4_001579"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31589..31591,aa:Arg,seq:cct)
     gene            complement(31697..32836)
                     /locus_tag="ACIZD4_001580"
     CDS             complement(31697..32836)
                     /locus_tag="ACIZD4_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5990518.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            33008..33142
                     /locus_tag="ACIZD4_001581"
     CDS             33008..33142
                     /locus_tag="ACIZD4_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990519.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(33135..33770)
                     /locus_tag="ACIZD4_001582"
     CDS             complement(33135..33770)
                     /locus_tag="ACIZD4_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990520.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(33883..34518)
                     /locus_tag="ACIZD4_001583"
     CDS             complement(33883..34518)
                     /locus_tag="ACIZD4_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HGC5990521.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(34552..35013)
                     /locus_tag="ACIZD4_001584"
     CDS             complement(34552..35013)
                     /locus_tag="ACIZD4_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HGC5990522.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(35143..>35246)
                     /locus_tag="ACIZD4_001585"
     CDS             complement(35143..>35246)
                     /locus_tag="ACIZD4_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HGC5990523.1"
                     /translation="MEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
BASE COUNT        11659 a         6032 c         7282 g        10273 t
ORIGIN      
        1 aaaggctttt tgcagcttga tttttaaaaa aatgtttatg aataaaaaaa gttgttcccg
       61 gatttcccag aaaaggtggt agaaagtggg ggattgtggt agactaattt tagttagtgg
      121 aggaatgggg ggctttcaat gttgatgggt gaattccaac ataatattga tgcaaaagga
      181 cgtttaatcg tgccctcaaa acttcgtgaa gaacttggcg aaaagtttgt tctgacacgc
      241 ggattggatg gctgtctttt cggctatccg atgagcgaat gggaaaatct ggaagctaaa
      301 ctgaacgaaa tgccgttggc taaaaaagac gcacgtactt ttgtgcgatt cttctattcg
      361 gctgccactg aatgcgaact tgataaacaa ggacgaatca atatacccag cacgttaaga
      421 aattatgcag ctttgacaaa aggttgcgta gtcatcggtg tatctaaccg aattgaaatt
      481 tgggatgaga cacgatggca agatttttct gcagcagcag aagagaactt tgacgaaatt
      541 gctgaaagta tgattgattt cggactataa gaataggaag aggctgacta atgactgaaa
      601 catttcaaca ctatacagtc atgttgaaag aaacggtaga tggattgaac atcaaaccgg
      661 atggcgttta tgtagactgt acactcggcg gtgccggaca tagtgaatat ttattaagcc
      721 aactaagttc taaagggcat ctgtatgcgt ttgaccaaga tcaaaaagca atcgatcacg
      781 ccaagctgcg tttagcttct tatgtcgaac aaggtatggt cacatttatc aaagcgaact
      841 tcagagaatt agaagaacgc ttgagtgagc atgtagataa ggtagacggc attttgtatg
      901 atctaggggt ttcctctcct cagctagatg aagcagaacg tggatttagt tatcatcaag
      961 atgcaccgtt ggatatgcgc atggatcagt cagctccttt atccgcttat cacgtaatta
     1021 atgaatattc ctaccatgaa ttagtaaaga ttttcttccg ctatggcgag gagaaatttt
     1081 ccaaacaaat tgctcgtgaa atcgaacgag tacgaaaaac aaaaccaatc caaacaactg
     1141 gtgagcttgt cgaaatcatt aaacaagtca tcccagctcc cgcaagaaga aaaggcgggc
     1201 atcctgcaaa aagaattttt caagctgtgc ggattgcagt aaatgacgaa ctcggtgccg
     1261 aagaggcctc tttagaacag gcaatccggt tattgaaagt caatggaaga atcagcgtaa
     1321 tcacattcca ttcattggaa gacagaattg tcaaaagtat gtttaaagaa tatagtacgg
     1381 tacaagatct accaccggga cttcctgtca tacctgacga attccaacca gaactgaaag
     1441 tcattactcg taaaccaatc cttccttcag aggaagagct aacagaaaac aatcgatcac
     1501 gcagtgcaaa gttacgtatt gcagaaaaaa taagaatgaa agaggagtag aatgatggca
     1561 gaattaaaga aaatgcaaga ttacgaatat gatttacctg aattggtgga tcagccggaa
     1621 caacaaatgc ctgattcttc ttcgaatcaa gaaatcattc ttccacaatc accggcaaaa
     1681 cgattaaagc agatttctgc tttggaaaaa attgctgtgg caagcgtggc gattgctatt
     1741 gttgctttat gtgttttaac agttatgctg cgcacaaata tcagcggagc tgaaaaagaa
     1801 atcacgtcaa tacaaacaga aatcaatgat aaaaagcaag aaaaaacgag tttagaacaa
     1861 gaaaaaaacg aactttctcg tactgaacgg attaaacaaa tcgcagaaga aaaaggattg
     1921 tctattaatg acgacaattt aaggaaagtg aagtaaatga gtcttaaaaa taaaattcgg
     1981 cggtttatgg aaaagaaaaa tctaaatccg atgaacaatc gcaaaaaagt aggtatcatt
     2041 ttatttgcta cgagtattgg attgttcttt ttatttgccg tccgtttctc gtatatcgtt
     2101 attggaggtc atgttgctgg tacctcatta gctgaaaaaa caaaacagtt gtaccaagga
     2161 agtgaagtag taaaagcaaa aagaggaacg atttatgatc gtaacggtgt ggcgctcgca
     2221 gaagatgcct cctcttattc aattaaagcg atactctcaa aaacatatac ctctggggat
     2281 aaaaaactgt atgttgaaga aaagaatttt gataaaatag cagaaatcct gcataagaat
     2341 ctttctatag acaaaaaaga tgcactgaat attttagagg acggcgcaaa aaaagagctg
     2401 tatcaagttg aatttggtag ctatgggaaa aatatctccc aagaaaccaa gcaaaacatc
     2461 gaagcggaca tgaaaaaaga aggtgtcgct ggtctttatt ttgtcgacca tcaggctcgg
     2521 atgtatccaa atggcgtctt ttcttctcat tttattggat acgcagttcc agacaaagat
     2581 gagaatggct tagttggtaa actaggtttg gagtctgctt acaatgatat cttgagcggt
     2641 aaagatggta agattattta tcaaaaagat aattttcaaa atcctctgcc aggtacagtg
     2701 gcagaagaag aaaaagctgt cgacggacaa gatatctaca cgactttaga cagcagacta
     2761 caaagttatt tagaaacact gatggatcaa gtaaatgaag aatatcagcc agaagaattg
     2821 acagcagtcc tgatgaaagc aaaaaccgga gaaatcttgg caatgggaca acgacctact
     2881 ttcaatcctg aaacaatgga aggattgact ggaaaagatg ctatctggcg taatttcttg
     2941 gtacaagata gttatgaacc aggatcaacc atgaaagttt tcactactgc agctgctatc
     3001 gaagaaggag aattcaacga gaatgaaacc ttccaatctg gaaaaatcca agtagaagat
     3061 gctacgatca atgaccatga ctttggtgaa aaaggtgtgc tgaccatgcg tcaagctctt
     3121 tcatggtcaa gtaacgtcgg gatggtcata ctggaacagc gattaggcgg acgatggtat
     3181 aactatttac aaaaactggg atttggacaa agtactcatt ctggattaga tgatgaagta
     3241 aacggtgctt tacctacatt aaatattgtc gaccgagcaa tgagtgctta tggacaagcg
     3301 gtaggtgtga cgaatttcca aatgatgaaa gctttcactt ctattgcgaa taacggtaca
     3361 atgattcaac ctcgatatat cagcaaagtg gtggatcccc aaactggaga agagcgaaca
     3421 actcaaacag aagttctagg gcaacctttt tcaaaagaaa caacagaaaa agtccgtgaa
     3481 tatatgagag atgttgtcga aagcgaaaac tacggtagtg cttatggtgt atatagtgta
     3541 cctggataca atgtatcggc aaaaaacgga acagcccaaa tcgcttctga tacaggggga
     3601 tatcaaacag gagatacagc ctacctgtat tcgattgtgg agatggttcc ttctgaagat
     3661 ccagactatg tcttgtatct aacaatgaaa caccctaaga catatgatcg aatggcattg
     3721 gctaaaatcg caaatccatt gatgaaacgg gcaatggatt ttaaagaaac tgaagaagat
     3781 tcagatacag aaacaaaaac agaaaaagta tccgtagccg attatcgtaa tcttgaagcg
     3841 gacgttgcag cagctgatgc tcaaaaaagt ggactgcaac ctgtagtgat cggtaatggt
     3901 aaaaaagtac aaaaacaatc tactgccaac ggtgatcagt tgatctctgg agaaaaactg
     3961 atcctatata ctggtggtga taagctgatg cctgacgtaa caggatggtc aaaagcagat
     4021 atcatgaagc tggggaaaat cctcggtatt gaagttagtt ttgatggaga tggttattgt
     4081 gtcaaacaag aacttgctcc atatgaaaaa atcactgaag acaaacttag ttttacttta
     4141 gaagaataag aagagaaata ggagagaaaa gagcatggaa tggacacaag cattgattcc
     4201 cattgtcagc agttgtgcaa tgacaattgc cgcaatgccg ctatttattg gttattttca
     4261 aatgaaaaag caaggtcagg cgattcgtga ggagggacca aagtggcaca atagcaaagc
     4321 cggaactcct acaatgggcg gcttagtgtt tctgatcggc tctattttga caggaatttg
     4381 ggttggagct tggcaaaaac agctaactcc tactcttttc atcttgcttt ttgtattagc
     4441 gttatacgga gtaatcggct ttcttgatga ttttataaaa atattcaaga aaagaaacat
     4501 gggactgaac tcgaagcaga aattgattgg acagattcta gggggaatca tcttttatct
     4561 tgtttaccgt tctgaaggtt atccaggtgt attgaatttc ttcggactag atctaccttt
     4621 aggaatcatt tatggtattt tcgctctctt ctggcttgtt ggattttcaa atgcagtaaa
     4681 tctgacagat ggcatcgatg gattagttgc tggcttagga agtatctctt ttgcagctta
     4741 cggtctaatt gcttggcatc agcatcagta tgatgtatta atcatttgct taagtgtttt
     4801 aggaggttta ctgggtttct tcgtctacaa cagaaaacct gccaagattt ttatgggaga
     4861 tgtcggttca ttagcgttgg gcggactttt agcggcaatt tctataatgc taaaccaaga
     4921 atggacattg cttttgattg gtttgatcta tgttatggaa acagcaagtg tgatgcttca
     4981 agttacttcc tttaagctta caggaaaacg aatttttaaa atgtctccaa ttcatcatca
     5041 ctttgaaatg tgcggatggt cggagtggaa gattgataca gttttttggt tgatcagcat
     5101 tgtgacttcg ttgatcacat tatggatcgt ttggtaggag atgacgggaa atgaaaaaaa
     5161 tatcaacata tgaaaataag aaagtgcttg tcttaggact cgcaaaaagc ggagtaagtg
     5221 cggccaaatt attacatgaa ttgggcgcac ttgtcaccgt taatgatgga aaaccttttg
     5281 acgaaaatcc ggaagcacaa gagctgcttt ctttagggat aaaagtaata acaggtagtc
     5341 atccaatcga attgttggat gaagaatttt cattgatggt caaaaatcca gggattccct
     5401 acagtcatcc tttagtagca aaagcccaag aaatgggtat tccggtaatt acggaagttg
     5461 agctagctta cgaagtagcg gaatgcccaa ttattgggat tacaggaacg aacggaaaaa
     5521 caacgacaac aacgatgaca ggactactac tgaatgcagg agcagatcaa ggaattgcac
     5581 gtttagcggg taatattggg tatccagcaa gtggtgtagc gcaagaagca aaatcagaag
     5641 ataaaattgt gatggaattg tctagcttcc aactcatggg aatcacagat ttccgccctc
     5701 atatagcggt gattaccaat atctatgaag cacatattga ttatcatggt acaagaaaag
     5761 aatatgtcaa agctaaatgg aaccttcaaa aaaacatgac agaaaaagat tatctgatcc
     5821 ttaactggaa tcagtcagaa ctacaagaat tagcgcaaag aacaaaagca cgcgtactgc
     5881 ctttctcgac aaaagaagtg ttggaagacg gtgtgtatgc tgacgattac tcaatatact
     5941 ataaaaaaga aaaaataatg gaaatatctg aacttggcgt accaggtaag cataatgtag
     6001 aaaatgcact agctgctatt tctgtagcaa aattgtatgg tatatcaaat gaagctatac
     6061 gagaaacgtt gcattttttc catggcgtac cacatcgtac gcaatatgta ggagaaatcc
     6121 aaggcagaaa attttataat gattcaaaag caaccaatat tttagcgact aaaatggctc
     6181 taagtggatt tgaaacgtct aaggtcgtgt tattggctgg cggattagac agaggaaata
     6241 catttgatga attaattcct tcattaaaag gaatcaaagc aatggtcgta tttggccaaa
     6301 caaaagaaaa gttgatggat gctggaaaaa aagcaggcat cgagacaata gtaacagccg
     6361 attctgtaga acaagcagtt cctttagcat tagaaaacag tacagatggt gatgtagttt
     6421 tattatcacc agcgaatgcc agctgggatc aatacccaaa ttttgaaact agaggaaaca
     6481 gattcatgga agctgtgaac cgattaaaat agaaaaagta gaagcgagcg ataaaaaatg
     6541 aaaattttgg ttacaggcgg aggaacaggg ggacatattt atccagctct tgcctttgtc
     6601 aattatgtaa agactcaaga accgaatgct gaattcatgt atgtgggagc aaaacgaggt
     6661 ctagaaaaca aaatcgtccc tgatacagga atgcctttcc ataccttgga gattcaagga
     6721 tttaaacgaa aaatttccat gcataacatc aagacggtcc gattgtttct taagagtatc
     6781 cgtcaagcaa aaaaaatcct cagtgatttt caaccagata tcgttatcgg tactggagga
     6841 tatgtttccg gagcggtagt gtacgctgca gccaaaatgg gtattccaac agttatccat
     6901 gaacaaaaca gtgtaccagg tgttaccaat aaatttttaa gccgatatgt ggatcggatc
     6961 gctctttcat ttaaagatgc ggcttccttt tttcctgaaa acaaagcagt tcttgtaggt
     7021 aatcctcgag cacaagaagt agcagatact aaaaaatcag atattttgaa aacatttgat
     7081 ttggatccag aaaagaaaac agtcttgatt tttggcggta gtcaaggagc acttaaaatc
     7141 aatcaagcag tatcagtttt tttaagtgaa tatattcctt cttcttacca agttttgtat
     7201 gcttcaggag atagatatta tgaagagatc ctaaataaaa taaatcctga aatacaaaat
     7261 attagtgtcc agccttatat caaaaatatg gcagaggtca tggcttccag tgatctgctg
     7321 gtggggcgtg ctggtgcaac ttcgatcgca gaattcacag ctctggggtt accggcagtg
     7381 ttggttccca gcccatatgt tacgaatgat catcagacta aaaatgcaat gagtcttgtt
     7441 cacgcaggag cagcaaaaat gattgcagat aatgaactaa caggtgaatc actaagtcag
     7501 acagtcaacg aaatcatggg tgatgaagaa ttgcaaaagc aaatgtgccg agcttctaaa
     7561 gaacaaggaa tccctgatgc ttcaaaacgt ctttatgact tagtaaaaca aataatcaaa
     7621 aaataaaggc ggtggtctta gtgagtaaga aaaaagaacc aaaaaaattg tctcatccgt
     7681 cttctgatga aaacaatttg actccttggc aaaaggctaa ccgaaaatat ctggcagaac
     7741 aagagatgaa aaaccaagag ccaaaaaaag aagacataac attagataca cccctttcag
     7801 attctgaaga agaaaaaacg gttcaagagg aacagcaaga agaaagccag tccgagaaaa
     7861 aaatcgaatt ttttgaagag atcaagcaaa agaaaaacgg tggaccatat aacggttctt
     7921 ttttgaaccg gctgcccaat ttaaaaagtc aacggcacaa agtactattt cgtcggttag
     7981 ctttgatcat cactgtattg ggtataccgc tgattttttt gatctattat gtttctcctt
     8041 atagcaaatt acaagcagtt gcagtatcag gcaataagac agtcaacagc caagaaatca
     8101 tctctgatac aaaattgtca ttaggagaaa atgtttgggg acagtatttt catcgatcta
     8161 cttatatcga tcgccttaaa aaagcacagc caagaatcga aacagcaaat atacatttca
     8221 aagggatgaa tgaattcgat ttggatgtaa cagaatataa agagattgct ttgatcgcaa
     8281 aaaacaatca atactaccca gtgattgaaa atggaacagt attagatgaa aaagtagcaa
     8341 atcctacaaa aaatctccct atcttggaag agttcaaaga ctctgcaaaa atcaaagaat
     8401 taacaaagca atacaatcag ttatcatcag aattacaaaa agcaatttct gaaatcaagt
     8461 acacgccaag agcaagcaat aaaaatctga tccaattgaa tatgaatgac ggcaatcaag
     8521 ttattgtaaa tatcaataat cttgcgaacc aaatgaaata ttattcgcaa gtagccaaag
     8581 atatggatga aaaaggtgtg atcgacatgg aagttggtat cttctcgcat ccttacggta
     8641 gcactcaaga aacggaagaa tcgggccaat cggaagaaac aactgaaagt gaagaaaatg
     8701 cggatcaaac aaacgaatca agtgaagagg cagaaacgca aaaagcacaa acacctggat
     8761 cgtctagcac aaacggatca tctgattcaa atgattcaag tgaaacaagt caaatagaag
     8821 ataatccaag tacaactccg tcaagtttaa atgaaaattg ataaaacaac tttaaaaagt
     8881 aagaatgtac tttctaaaaa ccagtaattt atggtagaat tggaagcagt gaatatatct
     8941 attaataagt atattttaaa acggacgcta gttgttcgct tgtatatgga atagtaagta
     9001 ggagggaatc ccattcatgg caaaaacagg aatgtatgta ggccttgata ttggaacgac
     9061 atctgttaaa gttgtcgtgg ctgaatatat cgacagccaa atgaatatta ttggagtagg
     9121 aaacgcaaaa tcagaaggga ttaaccgagg cattatcgtt gatatcgata aaacggtcca
     9181 agcgatacaa cgagcagtac gacaagcaga agaaaaagca ggtatccaga tcaaaggcgt
     9241 aagtgtcggt ttgccagcaa acatgcttga agtagaaaat tgccagggaa tgattgcagt
     9301 taacggagat tcaaaggaaa tcaccgatga agatgtcaga aatgtggctt cagctgccct
     9361 tgttcgttca atacctcctg aacgtcaaat cgtgtcaata ttgccacaag attttactgt
     9421 cgatgggttc gagggaatca aagatcctcg tggaatgatc ggcgtaagat tagaaatgta
     9481 cggtctgttg tttacaggac ctaaaacgat catccataac atacgtaaat gcgtggaaaa
     9541 tgccggatta atcgtcaacg aaatggtgat tactccttta gcgctgactg aatcaattct
     9601 ttctgacgga gaaaaagatt ttggtacgat cgtcattgat atgggtggcg gccaaacaac
     9661 aacggctgtt atgcatgata agcaattgaa gtttaccaat cttgaccaag aaggtggcga
     9721 atttgtcact aaagatatct ctattgtatt aaatacgtca tttaacaatg cagaagcgtt
     9781 gaaaataaac tacggggatg catacccaga acggacatca ccagatgaag aatttccagt
     9841 agatgtgatt ggtcagtcag aaccagtgaa agtcgatgaa cgctacttgt cagaaattat
     9901 ttcagctcga atggaacaga ttttcaacaa agcaaaagat gcattggacc aaatcgaagc
     9961 attagagttg ccaggtggcg tcgtattgac aggcggagct gctagtcttc ctggtgttgt
    10021 ggacttggca caagaaatct tcggcgtaaa tgtaaaattg tatgttccaa atcacatggg
    10081 gctgagaaac ccggtattta caaatgtaat aagtatcgtg gattattcag caaacttgag
    10141 tgaagtgtat caattggcaa aaattgctgt tacgggtgaa acctcagcag ctcgtcaaat
    10201 ggtagttgaa caagaaacaa caaacacata tgagagctat gaagcacctg aagaaacaat
    10261 ctacgatgag ccggaaccaa aagagtccgg agaaaatgta aaaaataaaa tcaagggttt
    10321 ctttacaaat atttttgatt aattcatcct gggaggaata agatatggaa ttctcaattg
    10381 ataataatat caatgacggc gcagtaatca aagtcatcgg agtcggtggt ggcggtggaa
    10441 atgctgtaaa ccgaatgatt gaagaaaacg ttaaaggtgt tgaattcatt acagccaaca
    10501 cagacgtgca agcattaaaa aattcaaaag ctgaaacagt tatccaatta ggccccaaat
    10561 atactcgtgg tttaggtgct ggttctcagc cagaagttgg acaaaaagcg gcagaagaaa
    10621 gtgaacaatc cttacgcgaa gctttagacg gtgcagatat gattttcatc actgcaggaa
    10681 tgggtggagg aaccggtaca ggtgctgcac caatcgttgc aggtatcgcg aaagaattgg
    10741 gcgcattgac tgttggtgtc gtgacacgtc cattcacttt tgaaggaccg aaacgtggcc
    10801 gttttgctgc agaaggtatc gctcgtttga aagaaaatgt ggatacatta ttaattatct
    10861 caaataaccg tttattagaa gttgtagata aaaagacacc gatgcttgaa gctttccgtg
    10921 aagcagataa tgttttacga caaggtgtac aaggtatctc tgatttgatc acagcgccag
    10981 gttacgttaa ccttgacttt gctgacgtga aaacagtgat ggaaaaccaa ggtacagcat
    11041 tgatggggat cggtgtggct agtggagaag atcgcgtagt agaagcaacg aaaaaagcaa
    11101 tctcctctcc attgcttgaa acatctattg atggagctga acaagtactt cttaacatca
    11161 caggcggttt ggatatgaca ttgttcgaag cacaagatgc ttcagatatc gtagcaaatg
    11221 cagcaactgg cgatgtaaat atcattctag gtacatctat caatgaagaa atgggcgatg
    11281 aaatccgtgt gacggtcatc gcaacaggta tcgatgaatc aaaaaaggaa cgcaagtcta
    11341 gccgaccagc tagacaagca caaatgcaat cacctgctca aaagactgta ttagatatgg
    11401 atcaagctaa accaacttct tcagaagaag aaaacagttt tggcgattgg gatatcagac
    11461 gtgaacaaaa tgttcgtcct agagttgatg attccaattt tgacaatatc gaaaaaaaag
    11521 aatttgatac attcaaccgc gaagaaacaa aatctcatgg cgatgatgaa ttaaatacgc
    11581 caccgttttt ccgtcgtaaa aaataaagga gaggaagagc acatgattgc tgacaacttg
    11641 cagaaaatca agcaagaaat tcaggattcg tgtgctcttg ttcatcgtga tccgaaagaa
    11701 gttacattag tagctgtaac aaaatctgtt gaatccgctc aagctgaaga attggttaga
    11761 gctggcgtta tgaattgtgc agaaaaccga gtagataaat tattagaaaa gaaacaagat
    11821 ttatttgatt ttcctgaaat aaagtggcat ttaattggta atttacagcg cagaaaggta
    11881 aaattgattg taaatgaaat tgattacttt catgcgttgg acagtttaag attagcagaa
    11941 gaaatccaga agcggttaga gaaagaatta tcctgtttta ttgaagtaaa tgtttctggt
    12001 gaggaatcaa aacatggaat ttcaccagat gagcttttac cgtttgtgga atctttagct
    12061 gcctgcacaa aaatcaaggt tgttgggttg atgactatgg cgcctaaaga agcttctgat
    12121 gagcaaatcc ataaagtgtt tggtacgctg aaagaattgc gtgatcttgt tcaagcaaaa
    12181 ggttatgccc atgcaccatg tagtgaatta agtatgggga tgagtcaaga ctttcaaatt
    12241 gcgattgaag aaggtgcaac atttatccgt gtaggaacag cgctattcaa agacgaataa
    12301 aggaggaaca aaaatgccgc ttttaaacag aggagcaatt gctaattttt tcggattagc
    12361 tgatgaggaa gagtacgaat accaagatta tcctgaaaca acaaaaaagg ctgtacagcc
    12421 aactaaaaaa aatacaacac agaatcaatc aactcattct gtatctgctg cgaatactca
    12481 tgaaaaacaa aaaacggcga cttcacgtcc tgtaacgcat gaaagtattc agccggctga
    12541 aaagaaaaaa gtaattgaac tacatcaatc acctacaaaa actgtagcga aagaaagaac
    12601 agcttcaaga acctctacac aacctaaagc aaatcttgct ggaaaaatca ctgtaatgga
    12661 accaagagct tattctgaag ctatggcgat tgctaaacga atcattgctg gagaagcaac
    12721 cttagtgaat tttcatttag tagaagaaaa acaagcgaga agaatcgttg attttctaac
    12781 aggaacagtt tatgcactag atggagatat caaacgtgtt ggagatgaga tttttctttg
    12841 tacaccgact gggatggaga ttgacagttc aaccgctcaa tcttttgcag atgcgaattt
    12901 gtttgatctg taagaggagg aactacgatt tatactattg cactattact tcatttactt
    12961 caacgggcag cctatttcta tagcattatc ttgatggtat atgcattgct ctcttggttt
    13021 ccaggcgggt atcaatcagg gctaggacga ttattagcta agatctgcga accgtatatc
    13081 agtttgttcg atcgtctgcc tttgaggatt ggacccttgg atttcacaat tttaggggca
    13141 atcctgatct tgaacttagc cgtacaaggt ttagcacaga tcgttatatg gataactgtc
    13201 catttagttt attgattgaa gcaacaaaat ctttattctc agaatagata ggaggggaaa
    13261 attttggatg caaatgtata ccagcacttt cgggcagatg aacgtacatt tatcgattcg
    13321 gtaggcgatt ggattgaaca ggttcaagga caatatgcac cctatctgac cgaatttctt
    13381 gacccaagac aatcctatat tttagaaaca ctgattcgac aaagcagtga tttgcgtttc
    13441 atgttttatg gcggatatga acaggcagaa agaaaaagat gtttgatttt ccccgattat
    13501 tacgaacctg tagaggaaga ttttgaaaca gcattgtatg aaatccatta tcctagcaaa
    13561 tttgccagcc taagtcatgg gaaaatcctt ggaactttag tgggaacggg gatcaaacgc
    13621 tcttactttg gcgatatcat ctcggacggt gatcgctggc aagtatttat tgcaaatgag
    13681 gtggatcatt ttgttgctgc acaagtaaca aagattggaa aggttgctgt acgcttggaa
    13741 ccaatcaaat acacagaaat gattatgccg aaagatagct ggacacaaga aagaggaaca
    13801 gttagttcca tgcgactaga cagtgtgatc tctgagattt ataatatttc cagacagcgg
    13861 tccaagcagc tgatcgaagc tggtaaagta aaagtgaact ggacagaaaa tacaagacct
    13921 gattttgtac ttgaactatt agatattatt tcagtcagag gttatggcag agtccagatc
    13981 caagaacttg aggggaagac gaaaaaagaa aagtacaggg tactgttcgg tgtattacgt
    14041 aaataaaata aaaaggtggt ttactcatgg ctttaactcc attagatatc caaaataaga
    14101 cattcccgac aaaaatgcgg ggatataatc aagacgaagt agatgatttc ttagatttag
    14161 ttgttcgtga ctatgaggaa ttgactcaaa gaaatcgaga attagaaaaa gcagtcaaac
    14221 attctgaaga aaaacttgag tacttcaatg aattaaaaga tgctttgaac caatcaatca
    14281 tcgtagctca agatacggct gataaagtaa aaacaagtgc aagcaaggaa tccgaagtga
    14341 tcgttacttc tgcacaaaac aaagcagatg agttagttgc gaacgctgaa aaacgtgcac
    14401 atcaattaac aactgatgca gaagaaaaag caagaaaaat cttgacagat gcaacagaaa
    14461 aagcaagaca gcttgcgaca gaaactgaag atcttaagaa aaaaacacga gtattccatc
    14521 aacgtatcag cttgatgctt gagtctcaat tagaacaagt gaaaagtccg gaatgggatg
    14581 aaattttaca accattctcc agctacgtga ctgacagcca tgaagtgatc aaagaagttt
    14641 tagcaaaaca gcttgacaat gaaaatgata ctgatgtaaa ctcagacaca ggagtcatag
    14701 aagcacctat gacggcattt gatacacagg ctattgatat ctcgatcgtg cctggtgaaa
    14761 atgaaaacga gtagaacaga aaagcacttt gttattctta aagcgagccg atgagagtgg
    14821 aagttcggta agacactgca tggtgaaaga tcctctactt gagacctgct tttccgaaat
    14881 tagagtaaga agcagcggct gacctcgtta ttggtcacag agagtttgca ctagatagat
    14941 gcaactaaat ttgggtggta ccacggcatg ttcgtccctt gcggctgaac atgctttttt
    15001 gtgtccggaa aacaaataaa ggagtgtatg gttgaatgaa aatgaaagaa accttgcaat
    15061 taggaaaaac aaaattccct atgcgtggta atttgccaaa ccgagaaggc gagtggcaaa
    15121 aagaatggga agaaaatcga atctaccaaa aaagacaaga gttgaacgaa ggaaaaccta
    15181 gctttgttct tcatgatgga cctccatatg ccaatggtaa tatccattta ggacattcat
    15241 tgaataaaat cagtaaagac attatcattc gttcaaaatc aatgtctggc tatcgtgcac
    15301 catatgttcc aggatgggat acacatggat tgccgattga acaagtattg gctaataaag
    15361 gcgtgaaacg taaagaaatg tccatggcag aatacttgga aaaatgtcgt gaatatgcac
    15421 tttcccaagt agataagcaa cgagcagatt tcaaacgcct aggagttgca ggagattggg
    15481 aacatcctta tgttacatta gatccttctt atgaagctgc acaagtacgc gtatttggta
    15541 aaatggctga aaaaggctat atttacaaag gattgaaacc aatttactgg tctccgtcaa
    15601 gtgagtcttc tttagcggaa gctgaaattg aatataaaga tgtaaaatct ccatctattt
    15661 ttgtagcttt caatgtcaaa gacggcaaag atattcttga tgaagataca gcttttgtca
    15721 tttggacgac aacaccatgg acattgccag caaaccaagg tattgctgta aatccaaaat
    15781 ttacgtatgt attggtggaa gccgatggcc gtaagtttgt cgtagcgaaa gatttgctag
    15841 aaacagtcca atcagaaatc ggttgggaaa atgtaacagt tctaaaagaa tttgctggac
    15901 aagaaatgga atatatgact gcaagtcatc cattctatga acgtgaatca cttgtgattt
    15961 taggcgatca tgttacttta gacgctggta ctggattagt ccatactgct ccaggacatg
    16021 gggaagatga ctatatcgct ggtagcaaat ataaactatc tgtagtgtca cctgtagact
    16081 caaaaggatt gtttacagaa gaagcacctg gatttgaagg tatcttttat gacaaagcaa
    16141 atcctatgat cactgatcta ttaaaagaaa aaggagcttt gctgaagcta gatttcttta
    16201 ctcatagtta tcctcacgat tggcggacga aaaagcctgt gatctatcgg gcaactccac
    16261 aatggtttgc atctatcgat aaattccgtc agaatatttt ggatgaagta gaaaaagtag
    16321 agtgggttat cccatggggt aaaacacgtt tgtataatat gatccgtgac cgcggcgatt
    16381 gggtaatttc ccgtcagcgt gcatggggag taccacttcc gattttctat gctgaaaatg
    16441 gagaagcaat catcacacca gaaacaatcg aacatgtggc aaaattattt gctgaacatg
    16501 gatcaattat ctggtttgaa aaagaagcga aagaacttct tcctgaagga tttacccacc
    16561 caggttctcc taatggcgaa tttacaaaag aaaaagatat catggatgtc tggtttgatt
    16621 ctggttcttc tcatgaagct gttttacgtc agcgaccaga attatcattc ccagcagata
    16681 tgtatttaga aggatcagac caatatcgtg gctggttcaa ctcaagtatc acgactagtg
    16741 tggctatcaa tggtgtagca ccatacaaat cagttatttc tcaaggattt gctttagatg
    16801 gtgaaggccg taagatgagt aaatctttag gaaacatcat tgcaccagaa aaagtgatca
    16861 aacaatttgg tgcagatatc cttcgcttat gggtatctag tgtagattat gaagcagatg
    16921 ttcgtgtttc tatggatatc ttaagtcaag tggcagaagt atatcgtaaa atcagaaata
    16981 cgatgcgttt cttattagcg aatacagaag atttcgatcc taaaaaagat actgtttcgt
    17041 acaatgattt acgttctgta gacaaatata tgaccgttcg attgaaccaa gtaatcaaag
    17101 aaatccgaga agaagggtac gacaaatata acttcatgca tatttaccgt acagttatga
    17161 acttcttgac ggttgatcta tcgtcattct acctggattt tgctaaagat gtagtttata
    17221 ttgaagcaga agatgattat caacgtcgtt gcatgcaaac tgttttctat caaacagctg
    17281 tagctttgac aaaattattg actcctatca ttccgcatac agcagaagaa atctggtcat
    17341 tcctgaaaga agaagaggag tacgttcagt taagcgagtt tcctggttat gaagagtttg
    17401 caaaccaaga agaattgatg gatacctgga ctgctttcat ggacttccgt gataatgtct
    17461 taaaagcatt ggaagaagca agaaacagca aattgattgg taaatctttg gaagcaaaac
    17521 taactgttta tccaaaacaa caagttcgtg aaatgttaaa agctttggat gcagatattg
    17581 cacaattatt gatcgtttca ccagactact ttgaagttat ggcagcagat gaacaagtgc
    17641 cagataacgc tatggtattt gatgatgttg ctattacagt ggaaaaagca gacggggaaa
    17701 cttgcgatcg ctgtcgccaa gttcgtaaag atgtaggagt agatgaaaaa cttcctcatc
    17761 tatgcggtcg ttgtgcaaaa atcgttgaag acttctatcc tgaagctgta gctgaaggat
    17821 tcgaagaaaa gtaaaaggga aaagggggtg tgacatgttc tttgtcacac ccccttttgt
    17881 tatcaatcgt ttaattttcc acgttcacga taccagttat ctggttgcca gatccattcg
    17941 aatccgtctt tttcaagtag ttcgaaagct gctttaggtc ccattgatcc agctttgtag
    18001 ttgggaaaat ccggttgtgt ttggtcccaa gcttttcgaa tgacatccac gatatgccaa
    18061 gattgagcga cttcttccca atgagagaag ttcgttccat caccattcaa cgcatctaat
    18121 agtaattttt cgtaagcttc tgggctattt tcaaccattt ctgcactatt tctaaattcc
    18181 aatttgattg gttccgtttc aaatccttgc cctacttctt tcccattcaa ggataaagaa
    18241 aatccttcag ttggctgaat atagatcgtt agaacattag gtggaagtgt cgtatcgtca
    18301 catggttcat cgacagatgt tttgaataca ttaacaggaa cttgtttgaa tacgatgttg
    18361 atccgagtcc ctttttcagt caaacgtttg cctgtacgta catagaaagg aacacctgac
    18421 caacggaagt tatcgatagt gaatttgcct gcgacgaatg tttcagtctc tgattgagca
    18481 tccactttgt cttcttcgcg atagcccttg aattgtacac catccaattc accttgagca
    18541 tattgcccgc gaacgaagtt ttctaacact tcttcttcgt tataaatgcg gatagctttc
    18601 aatgctttga tcttttctgt acggatttct ttttcggaaa atgctactgg cggttccatt
    18661 gcaagtaatg ctacaacctg taaaatatga ttttgcacca tgtctttaag tgcgccacta
    18721 tgatcgtagt agcccccgcg atcttctaca ccgaggtttt cgccaaaagt aatttggata
    18781 ttgtcgatat agcgattgtt ccattgagcc tcaaaaatat tattggcaaa acggatagct
    18841 gagatgtttt ggatcatttc ttttcctaaa taatgatcaa tcctgaaaat atcttgttct
    18901 gggaatactt ctctgatttg ctggttcaat tcaaaagcag actggtaatc agaaccgaac
    18961 ggtttttcta tgatcaaacg attgaagcca ttttttgtca taatattttg tgatttcaaa
    19021 tgagaaacga tcgttccaaa aaattgaggt gccatagcca aataatagac acggttaccg
    19081 tttaattgat agtgtccatc taatcggtca gacaattctt ttaatgtctg ataatgcgtt
    19141 gaatcattta catcatggga ttgatagtaa aaatggcttg caaaggtagt tgcttcttca
    19201 tctgaaggat tcaatgcacg gattgtttct ttgacaactt cacggtagtg ctcatcgctc
    19261 cagggacggc gagcggttcc gattacagca aaatgctcgc ctaaatttcc ttttctgtaa
    19321 aggcggaaca aagacgggta caatttacgc tgggctaggt cacctgtacc gccgaatatc
    19381 gtaaacaata catttttttc attagacatg tggatacact cctttatatt ttatcgacaa
    19441 aaatcgtgct ggccgcctta aagctgacgg ggattttctt tctatcattt tggatagtga
    19501 tcggtccttc ataagctgcg atgtcaacga tctcatattc ttcgttgata ttcaggtcaa
    19561 tagtgactaa gtaatccaac aattcttttt catcaagcac tcgtgcgata cgcacttttg
    19621 taccgacagg ataggactcc aatgtttgtc ggcgttcttc atggacaact tcctcttttt
    19681 taggaatcga tcctccatga ggacaatgtt caggatgatt caaatagttt tctaaatgat
    19741 ctgcaagatg ttccgaagtc acatgttcca atacttcagc atcatcatgg acttcattcc
    19801 agctatagtc taaatgttca actaaaaaaa cttcccataa gcgatgtttg cgaatcagac
    19861 tgctagcttt ttgcagtccg cttgcagtca attgtacacc ttgataaggg gaatgttcta
    19921 caagctcttc tttcacaagt ttagaaatca tttcactgac agatgcagct gagacatcta
    19981 gactagatac gatttgttta ttgttgactt tcgttgtatc tccacctagt tctaaaatga
    20041 ttttcaaata atcttctcga tttggtgtca tattcgatca tcctttcatg gtaaaaaacc
    20101 atcattagta agtgtaacaa aaaaaacgtt aattgactat ttttctaaat aaaaaacaaa
    20161 ggatttttag acgtttttac aacaaaaaac gaaagatgat agagaagact cattctttcg
    20221 tttataaagg atatatatat acattgggag ggatctattt ttcagataac aacttatatg
    20281 aagtgtctgc agattcgtca taaagagttt gttcgggata agaaaagata agataaaaac
    20341 catactgatc acgtacgact aaacgatatt catctatttc taccacagat gtgccaagag
    20401 actgaccgtt gatcaaaaac gtgtaatcag atgtaatctg taattgttgt ttttgctggc
    20461 tatcactaaa gaaccatgta ccttgatact ttgagagtcc ttctgacttt tccgcttgtt
    20521 ttttcttttt caagtaaata aaacttgaga gaacggtaat gagtgaacca agaaaataga
    20581 tcattttttt tatcaccaaa tcactccttt atgagaaaat aatcgcatag acatattctt
    20641 tcttctttat ttcattgtac cgaataaaag ctaaaatttc tctaagactt tcgactggtt
    20701 tttttactgt ttttctacaa attatgatag gatacatagt aggaagaaag gtgacataat
    20761 ttgaagtatc agcaagtgga aatagctttt tttattgacc gcccgaatcg gtttatagca
    20821 cattgtatga aaaaagacgg agaaataatt attgcgcatg tcaaaaatac aggtagagga
    20881 aaagaggtcc tgataccagg cgctgaagtg gctattgtat ttgctcctgg acctaaacgg
    20941 aaaaccgcct atgatctgat tgctgtaaaa aagaagggtg actggtttaa tatcgatagt
    21001 caattgccta atcggctggc aattgatggt attttagacg gcacgatcct tttaccagga
    21061 ttaactggtc catttacggt atacaagcgt gaagtaactt atcttcactc caaatttgat
    21121 atttatttag agacggtggt cggacaaaaa gcatttgttg aagtcaaagg tatgacactt
    21181 gaaaataaag cgattggtgc ttttcctgat gcgcccacac tcagaggatt gaaacatata
    21241 ggagaattaa cgtatgccgc acaagatggt tatgccgctt atgtcttgtt tattgctcag
    21301 ttcgaacatc ttcatctggc aacgatccat gaagaaatgc aaccagcact agctgatatg
    21361 gttcgacatg cgcagcaaag cggagttcaa atcctcgcct ataattgtca agtatcggca
    21421 gatgaggtaa ctgtcaagca ggccattcca tttgatgtag atatcccttt tgaagatcct
    21481 atacaataga aagaaggtaa aataatgatc aacttaggta ttatcggaac aaattggatt
    21541 actcatcaat ttgtccaagc agctttaagc acaaaaaaat atgaattgac agcggtatat
    21601 tctagacatt tggaaaaagc acaggaattt ggttctcatt atgaagggga tatcgaattc
    21661 gcaacagatt tgaagacttt tttcaatatt actcatatgg acaccattta tattgcttct
    21721 ccgaatagtc ttcactttag tcaagctaag caagcaattt tggcaggaaa aaatgtgata
    21781 gttgaaaagc cagctttttc gacgccaaaa gaaatggatg aaatcatcca tttggcaaat
    21841 gaacacaatg tgtatttttt tgaagcagca agaaatatcc atgaatcagg ttttaaaaag
    21901 attgccgatt acttaccatt aaaagacgag ataatcggtg caaatttcag ctatatgaaa
    21961 tattcttcgc gctatgacca agtattagat ggagaagaac cgaatatctt ctcgactcat
    22021 ttctcaggtg gtgcattgat ggatttaggt gtttaccttg tatatgcagc tgttgcttgg
    22081 tttggaatgc caaaagaagt ccattatttc ccaagaaaga tttctactgg tgtagatggt
    22141 cttggatggg ggatcttacg ttatgagaat tttgatgtat cgatccagcc aggtaaaatc
    22201 ggtgattctt atttaccgtc agagatttat tttgactcag gaacgctagt gatgaatgga
    22261 gtcaatgcaa ttgaacaagc acaatttcat gatcgcgcgc ataaagaaat cattgatttg
    22321 gcggtaacag ctgcagaaaa tccaatggca gatgaagcag aggattttgc caatgtcatg
    22381 gctcatccga aagatccagc ttggggattg ttgtatgaag agtggatcga gctagctaga
    22441 aatgtgaacc aagtgattta tgatttaaga aaaaatggcg gcatcaaatt cgatgcagat
    22501 aatgaggaag atttttaatg aacgaatttg tacaagtatt tcccgaaaat tggcagaaaa
    22561 aatatgagga taaagggttt atctcacctt ctcttattca acgagcagtt tttcagccac
    22621 taagtaataa acaaagtata gtagcggttt ctcctacagg ttcaggtaaa acactggctt
    22681 atctttggcc tctactacta aacgtggaac caggtgaagc aagtgcgttg gtcatttttg
    22741 cttcttctca agaactagct attcaagtag cagatgttgc acgtgaatgg ggaaaagaca
    22801 aagagttgaa agtccaatct ttggtgggcg gagccaacgt caaacgtcag attgagggtt
    22861 tgaaggaaaa accagaaatc ttgattggta caccaggaag aatattggaa ttgatgaaag
    22921 caaaaaaaat aaaagcacat caagtgaaaa caatggtatt tgatgaagca gaccagctat
    22981 ttgacgctgg gaacagccaa atcattgatc aaattcttca tcaagctcca acagagtatc
    23041 agctagcttt tttttcagcg acagcagatc gttcccttga aagcattgaa aaaatcactg
    23101 ggaaaacgtt tgagacaatt gacgtgacag cagaggacga ttctcgaaaa ggactgagac
    23161 attacttttt acgtgtaccg atacgaaaga aagatgacta cttgagacgt ctcacgcata
    23221 tagaagattt tcatggtctg attttcttta atcaactgac tgaattaggc gtaatggaag
    23281 aaaaattgct gtatagaggt gtaccggtag gaagtctggc ctctgatcag aacaagctac
    23341 tccgaaaagc agcgctagaa caattcaaaa agaaaatggt cagagcactt ttgaccacag
    23401 atgtggcggc tagaggttta gatattacag gtcttcctta tgtagtgaat gcagaagttc
    23461 cgttaagtga agaagcttat ttgcatcgtt cgggaagaac tggtcgaatg ggtaatgaag
    23521 gaatagtaat tacactcgta caagataata atctaagaga tttaaaacgg cttttacgtc
    23581 catcaaatat aacacttgaa gagatttttt tatacggagg taagctgcaa actgagcagc
    23641 caaccaaaga agatgcagct cctgcagtaa ataaaaagta tgcgaaaact ttttctggaa
    23701 aggagcagaa cccagaatat aacaaagaaa aaataagaaa aaaagttaaa aataaatcaa
    23761 aaaaagagag aaataaagga gcaaggcgca aataagcgcc tttttatgct atgattatga
    23821 aaacgggaac aaaattggtt gccagaggag gggttatgtg aaagaacgtc aagaagagat
    23881 cttgcagcta ttgacagaaa accaacaagg attgacagca agtgatgtag ctgagcgctt
    23941 aactatcgat cgaagcaatg caagccgata tttaagtgaa ctatacaagg cccatcatat
    24001 tgtaaaaacc gctggccgac cagtcgttta ctctttgcca acggaaaagt caaaatctga
    24061 tgaagtgcat gtcgactctt ctacgcaagt gacttttgaa acactcgttg gagaaaatga
    24121 ttctttaaaa gtcagcatac agcaggcaaa agctgcgatt ctttatccac cgcgggggtt
    24181 gcatacgatt atttttggag aaactggtac agggaagtcg atgtttgctg aatgtatgta
    24241 tcattttgca atcgattcag agatgctttc tgcagatgcg ccatttgttt ctttcaattg
    24301 tgcggattat gatcaaaatc cgcaactgct ctttggacac atctttggga tcaaaaaagg
    24361 ggcttacaca ggagcagctc aagatagtcc cggtctaata gccaaagcag acggcggtat
    24421 attgttttta gatgagatcc accgtttacc gccggaaggg caggaaatgc tgtttacttt
    24481 cattgataaa ggtatttacc gtccgcttgg agaaagtgca caagtacatg aagcatctgt
    24541 tcagatcatt ggggcgacga ctgaatcttc agaaagtttc ttatctacgt tcaatcgacg
    24601 gattcctatg gcaatcacct tgccgaatct tgcttcacgt tcactggatg agcgttatga
    24661 aatcatctct ctttttatca aacaagaagc gaatcgtttg aatcaacgta tcgatatcga
    24721 aaaagaagcg attcttgcct tcatgcttta tgatgcggaa ggaaatatcg gtcaagtgaa
    24781 acgagacttg aaactagtct gtgcaaaatc ttttttacat taccgtactc atcatgagaa
    24841 aaagctaatc attcgaaaag aagaactttc ccttcaagta caaaaaggat tactgaaaat
    24901 caaggaaata ccggaacgtc tcgaccgatt catggacagc aaaagtcagt atttgacatt
    24961 tgaaccagga tttgctgatg ttgtctggtc acaagatcca gaacgaaaca tgcaggtcta
    25021 taacgatatt gaggaaaaag tcacttctct ttccgaaacc ggtgtggaga acattgatct
    25081 agagaccctc atttcaaaag atgtggatgc ttatttccag acatatgtca aagaattgac
    25141 taaaagttcg attcccaaag atcttttgcc agatgaaatc tggcggttaa ccaatcaatt
    25201 gtatgatgtg gctgaaaaac ggttagaccg tatttataat gaaaaagctc gttttgcttt
    25261 tgctttgcat ctgcaaagta cattggatcg tgtgagagaa ggtcatatga tcgtccaccc
    25321 agatttgaat aacgtacgga aaaattttaa gagggaattc caggtagcaa tcgatctttc
    25381 aacgatcatt gaagaagaag aacaagttga gattcctttt gatgaaatcg gctttattag
    25441 tatgtttctt tctatcaatc taggagaaag tgagcctgtt aaagaaaaca aagtagatgt
    25501 tctcatattg atgcacggca gacagactgc ttcaagcatg ttggagatgg cacaagaact
    25561 attaggaaca aaagtaggga aagcttttaa tatgccactg gttatggaag ttcaaacaat
    25621 gtatgaagaa gtgttacaat atgtcaaaaa ctatcaagag catttgacga atggcctact
    25681 cttgttaaca gatatgggat cattaaacac cttcagtgat ttgatttatg aagagactgg
    25741 cattcggacg aaagctatca cgatgacaag taccatgatt gtgatagaag cgatacggat
    25801 ggcaagtgtt ggaagaagct tagaagatat ttatcaaaat atccagcttt cctttgaatc
    25861 gatcgtacgt gatcagttca aagcggaaaa gtctgaaact ttacagcgta aaaaagccgt
    25921 aatcgtgaca tgctttactg gtgaaggagt agctgccaaa ttatatcagc gtattatgcc
    25981 agtgattaat caaaataagg tagaactgat ccagatgcag tttttagaac gtgaatcatt
    26041 caaaaaacac atcgatgcct tattggaaga atatgagatc aaagcaattg cgggaacagt
    26101 tgatgttgat tatcaaaata tcccattttt ttcagcctat gacgtttttg atgatgaaaa
    26161 actaaatatt ttaaagcgta tagctgatga tgagatcccg acagctaaaa ttgtcgattc
    26221 acttgctgga tcattaagcg atgtcttttc tattgatgaa ctgatccgtt cattgcaaaa
    26281 gacagttcag cagatccaga ccgatttgtc gattatcgtg gaacctggag tagatactgg
    26341 aatcgttatc catttagcct tcatgttaga cggattgatc aaacaagaaa gccatcggca
    26401 atttgagaaa ctgtctattt tctcaaaaat ttatcgtttg gaaatggata tcgttcgggc
    26461 aaacttgatg gcactagaac gaaaatatca ggtaaaaatt ccagaagatg atatcgcatt
    26521 tcttacacaa atgtttcttg aaaataaaat aaaaaaatga acacactaat catactgttt
    26581 acacactaaa catctgtgtg cgcactataa aaaagagcta aaaagcatga aaacgctatt
    26641 tcagctcttt tttttattgg catgcttctt gcgttatata aaagtgtaaa aaaataaaag
    26701 gagtgttaaa aatggcaaaa aaaacaatca tgttagtttg ttcagcaggg atgagtacga
    26761 gtttattggt cacaaaaatg caaaaagcag cagaagaaaa agggatggaa gccgatattt
    26821 ttgcggtctc tgcctcagat gcagataata atttagaatc taagaatgtc gatgtattat
    26881 tattaggtcc tcaagtacgt ttcatgaaag ctcaatttga acaaaaactt gcgcctaaag
    26941 gtattccatt agatgtcatc aatatgcaag actatggcat gatgaacgga gaaaaagttc
    27001 ttgcacaagc agaaaatcta atgaaataaa tcaagtatgc agttgggggt ataacaacgt
    27061 ggaagatcaa caaaatctag aagccatcat ggggttaatc atgtttggcg gtaatgcaaa
    27121 gagcgatgca atggaagcga ttgcggctgc taaaatcggt gattttgagt tagcggatag
    27181 gaaaatcgct gatgcagaag aatcacttat acaagcgcat catgcacaaa cagacatgtt
    27241 gacacaagaa gcacaaggaa atcatatgca agtgacatta ttgactgttc acagtcaaga
    27301 tcacttaatg acatctattg cgtttactga tttagcaaaa gaaatcatcg aactttatcg
    27361 tcgcgtatac agcgaataaa tacaacttct tttttgaacg gaagaagaaa aatttttgaa
    27421 cggatttttt attttgttat aaggagaact ctctttatat aaaaaactta taggaggaag
    27481 taaaaaatga acggactatc aagttggatg gagaaataca tcctgccggt tgccgcaaaa
    27541 atcggagcgc aaaaacattt agttgctttg cgtgatgctt ttatcggcat actgcccgca
    27601 acaatggcgg gatcagtcgc tgtaatgatc aatgcaatta ttcgtgattt accgcaacag
    27661 tttaacagta cctatgctga cagtttagca gcagacaaag gaatctttgc cgtattgaat
    27721 gtcatcatcg gaatcaatgg ttttgtctgg aacggtacac tagcaatcgc cggattgatc
    27781 tttgcctttt cttgggggta taatcttgcc cgagcttatg gagtaaatga tctagctggg
    27841 gggatcgttg gtttagctac cttgattcaa ggtatttcct ttggtccagc attatcagca
    27901 gcattagatg tgaatgttcc ttcaaatgtc gcagatgcaa tcaatagttc tgagattggt
    27961 gcaacgattg cagatggcac actgtcagtt ggattatggg gttggctaaa actagatcat
    28021 ttgaatggaa acgcttattt tacagttatg atcatgggag ctatttcagt cattattttt
    28081 tgtaaattga tgcttgccaa cattacgatc aaaatgcctg attcagtacc accagcagta
    28141 tctaaagcat ttgcagccat tttaccagcg acgatcgctt tatacgtcat tgctattatc
    28201 aattatatcg taggtcgtgt agctgatggg caactgatca ttgatttggt gcaaaaatat
    28261 attgcagaac cattcctagg attatctcaa gggttgggag cagtattgat cgtcacagta
    28321 tttgttcaag tattctggtt ctttggtatt catggatcaa atgtattggc accagtgcta
    28381 gagggaatct ggggacaagc acaactaatc aatattgata ttttccaaaa aggttataac
    28441 ggaaaaactg gtacaccagc cgtgttagat gcaatcgaag atggaaaagc ttatatgtgg
    28501 gtccgcggat cgttcgatgc ttttgcatgg tttggcggat caggcggaac gatcgtctta
    28561 ctgatagcta tcttgatttt ctctaaacgt gcagattatc taacagtagc taaattatcc
    28621 attgggcctg gtatcttcaa tatcaacgaa ccagtgatgt ttggtctgcc aatcgtattg
    28681 aatgcaatca tgtttatccc attcttgatt gctccagtag tagcaacagc aattggatgg
    28741 acagctactt atcttggcct agtcgctccg gtatcgcagc aagtcacatg ggtagtaccg
    28801 ccgttcttat tgtcattctt agcaacagga gcggattggc gggcaccgat cgtaacatta
    28861 gtatgtatgg tcgtgacttt cttgatttgg gcaccatttg tcatctctgc aaacaaaatg
    28921 gaccctgccg caggcgaaca acaataagat gaacgtgagg agcgggacgc tttaagtttc
    28981 gttcctcata atgaattttc gaggaggaac tgaaatgatt acaattgcca gtgcaatgca
    29041 acaagatgaa atcaaagaat tgttagaagg atacaatgaa gaaggaatga cttttacatt
    29101 taaagaaaaa caaggaatca agctgttctt tgaaacaagt gcagaagatc cggaagttgc
    29161 ggctaaaaaa gcaaaggaac taatcaaagc acagccttgg ggaacagtcc tttattttca
    29221 atcaacagct gtttagaaaa tggtttaaaa agataggatg gttgagatga taaaaaacgg
    29281 tttattttta tgtagtattg gttctttgat cgtgttgtat agtttgaatc cacattcgca
    29341 aaggtatgat ttgtatagta tggtcacagg tctttttcta acaggattag gaatctattt
    29401 cttcatgaag gggaaaaaaa gagaagaagc aaaggagaaa aataactaat ggaaatcacg
    29461 aaaaaattaa atattccagc atcgtttttt tacgataaag ttatggactc tgtccttttc
    29521 gatgtacgta aagcgaccgg caaatcagta actagaaaac agctgaaaaa tttggagtac
    29581 gtcaaacaat tctcgcaaaa taaccgggct cgcataaaaa tcgaagaagt cattgaaaac
    29641 cagtcttata agtttcgtac atcgacaacg aagaatgaat tcgtcgttca ttatcaaatc
    29701 aaaccattgg acgattcgac ctgtgaggtt cattacacag aaaaaatgga gtcttatggc
    29761 atgcttcaaa agttgaatga tatgctttta ggaacaatct tgatgtattt taaacggaga
    29821 cgtttcaaaa aaatgctaga tatgatcgaa gcaacgtatt aaatcaatga aacatggtac
    29881 tatttagtta ttgaaaaatg aagtaagcta gaaggaattt ttcataggaa gatagatctt
    29941 tcctgcgaat cctcactagc ttttttgtag gaaggggcag caaaatgaca aacaaagtaa
    30001 gagagctagg tgtatcttcg attgaggaaa tgtttgattt agccacttat gcatttaatg
    30061 gggcagatac acctgaaagg cgagaacgtt ttcgtacact tgcggagaat tcttggaatt
    30121 acggattttt tgatgaggag gatcggctaa caagtcaagt catggcgccc ccttttccag
    30181 tgaattttta cggacaagag tacctaatgg ccggcattgg ctatgttgct tcttatccag
    30241 aagcaagggg acaaggcggg atcaatcaga tcatggaaaa gatccttgaa gattgccgtg
    30301 atcgtaaagt aagcttatct tatctggcgc cattctccta tcccttctat cggcgctatg
    30361 gctatgaaca atcatttgat aaaatcagtt atcaactaaa cagtcgtgat gtgccgttta
    30421 tcaaaaaaaa atctggaaaa ataaagcgta tggattttga agatgcaaaa gctgcaatca
    30481 gaagaattta tgaacagatg ccggaaaacc aacgagctgg tctgaagcgc gaagactggt
    30541 ggtatacgta taaattcaag caaaaaggca attaccagtt tgctttgcat tttgatgata
    30601 atgaggaagc aacgggatat atcgtttatc agcttgcaac gtcttccttt attattgcgg
    30661 agtggggatt tttggatcat gatgcttttt gcagccttgt tcgcttcgta agttctcaca
    30721 atggtgcttt tgaaacattt gaatattcat gcggctacgg cggtaatgat caaaattatc
    30781 tattagaaaa tccatttgct tctgtaatga tcacacctta tatgatggcg aggatcgtag
    30841 atatttcttt gtttttggaa aattatccat ttaaaaagag acaagctgca tttgccctac
    30901 aaatagaaga agatcattat gcgaaatgga atgaaggaat cgtggaagta acaatcgaaa
    30961 atggaaaaaa tcatctctca aaagtagaac aaacaaaact cccaatcgtt cgaggaagta
    31021 tccaacatat cacgcagcta ttattagggt atcgtaaagt ggaagagttg gtattccaag
    31081 aaagaataca ggtgacaaaa gaatatgaag aaacgttaag ctcaatcttg ccacagcaac
    31141 agccaattct taatgactat ttttgataaa aaacgggtga tgacaatatt tttgtcacca
    31201 cccttttgtt tttcatttgg catttgaagg aaaatgttaa agtaaatcct cttttttcgt
    31261 aaatttgaat tttttgtttt cttttgtttt agggttttct tttttgtggt cttggattgc
    31321 ttctttcgta atcttttccc gatttttttt agatgaatct aagcgttctg cgtatacttt
    31381 ttcttttggc ttatcattca ttggaaagga cctccctaca ttatttcatt ctacctctag
    31441 tttatcatct gttaaggact agtggaaacg ttttgcctaa cttataagct gattttttta
    31501 gcagataagc ttgcaagtaa aaaacaaaca agctacaatt gatttattga aattgttcct
    31561 gtagctcagt aggatagagc aatcgcctcc taagcgatag gtcgctggtt caattccagt
    31621 caggaacgta taaataaccc ctgtatcctt tgcggtacag gggtttgttt tgtatttgtg
    31681 ccaaaaatgt gccaaactag ttatcatttt tatataaact atcgaacaca gtattgattt
    31741 tttctttatc ctgatcttca agctctcgaa caatatgaag ataagtagac attgtagttt
    31801 ctaaactgct atgtcctaaa cgtttcgata cgctaagtat atttactcct tgataaagta
    31861 aaatagatgc atgtgtatgc cttagtccat gcaaagtaaa ttgcttttca atccctaatt
    31921 cttttaattt tttgcgcaaa tatttgctga cggcgtttga tgaaactaat ccatttttta
    31981 agttgaaaaa aacaaaatta tgagggtttt tgatttcaaa attctcgaat aattcttttt
    32041 gattgatttt aaactttttt aagagatcaa tcgtatgttt atcaatggaa attttcctat
    32101 ttgaagtttc gttttttgtt tttccccatt catttaattt ataattccat gttttattaa
    32161 tagtgatgat ttgatcttcg aaatcgatat cttcccatgt taatcctaga agttcagcaa
    32221 atcgcattcc agtggcacca gcaactaaca cgagcatagg agaagagtac tgcgcagaaa
    32281 ggttttcttc tacgagtttc attaaagatt taaattgatc ataatctaaa tatttatctt
    32341 cttttggctt caatgaatct tttcctttga ttactgcttt tctagttgga tcaaacggaa
    32401 ttaatccttc ttctacggca tctttcaacg acgctctaat atggttatta aacttaataa
    32461 cggtagattt tacatggtct ttagcatact tatttaaaaa gcgttgatat cccactctat
    32521 ctaaatcaga aatcaatacc gctggcatat atttctttat gttcattaac gtatcttcgt
    32581 attttctata agtgatagga gatactgttc cttctttata aagttgcatc caatcctcaa
    32641 agtaatctga taataataga tttttgcgat cccctttaag gcctttgttc aagttatatt
    32701 ctaattcgtt ggcggcatct tttgcttctc cttttgtctt aaatcctgat tttcttatct
    32761 tcgtgtattt tccgtcatct tttttgtatg aaatttcgta ttgccaacta tttccacgtt
    32821 tgactaatct tgccataatt gaatcagctc tctttctctg atacaatagg aactataaag
    32881 aagcccattg tttgggtttt attatttttt gcacatcctt tttgcttgcc ggcgcaagga
    32941 tgtgctattt gtcgttttaa tggtataatt ggatgtgtat tagatcatcc aatcagaggt
    33001 gtttattatg attaaagtga tttttaaaag aataactgaa cttccagagt ttagattatt
    33061 tgttgattat tggtatgtct ggttttttat tgttgcattg ctgataggtc tagatgtcat
    33121 attagaaaga aaacttaagt aagagttgag ttaataaatt gaattcctaa atgagatatt
    33181 ttgtagccca tattttgttt gccgacatca cctaatacta tggagctaat cgttttttct
    33241 aacagaccaa aatcagataa tctatttaag ctaccatcta ttagctcttg tgaatagcca
    33301 gacatgctga tatttccagt gaaattttcg tttccacgac tcattaagca tgctaacaat
    33361 tgaatctcaa tcgatgttaa ttgattcagt acaagaagat aatactcctc gttatcccat
    33421 gaagcgttgt taattcgaag taaacaattc ttataaagat ttttatacat atctatttta
    33481 ttttgtgcct ttgatttttc tacctcgtca tttatccctt cgaatattcc aatgagttgg
    33541 tccttgttct ctaagttgaa aacatcttct ggaatttgat cgcgaatgtt ttctaatgat
    33601 tcgtttaaat ttttgtagaa tttctcgatg cgtttgaaac gcttctcgtt tttagaccca
    33661 aaataaagtg actgcacaac gccaccaata taaggaattg ctccaatacc gccttcaact
    33721 attaattcaa gatattcttt tttggttagt ttttcattgc tattatccat agttacctcc
    33781 tattttgtca tttcctttac aagcattgtg actcctgatg gcactctttt gtataggttt
    33841 tattattgtg cacaatctaa ctcttagtgg ggcgtggttc atttattttt tacttacttt
    33901 actattaatc atatcccatt gagcatagga tttttctatg ttcgatcctc ttgaactaat
    33961 ttctcctgta aaagttactt tatcgccctt tgtaaaggta tcagcattgt ttaagtcctt
    34021 cgcaaaaatt acatatgaaa ctttaggtgt tgcagaaata tcattccaac ttttatcatc
    34081 gtactctttg tctgctataa tggctattct agtagtcatt gattcgataa cagttccttc
    34141 aaaagtatat gttttaccac taatatattt agtaaaagct gtattttgct cagtagctgg
    34201 agtaatagaa taataactat ctaagaaagc accccagtca tgattatttg tctctaaaaa
    34261 ttcttcaaat tgagttaggc ttttattgct gctgttagat gtagtagttt gagtatcaga
    34321 tgatgagctt tcctgtttgt tattgtcatt tgcctcgttt gatgaggaaa gcgagaaacc
    34381 tacggtagta aaaataatcc cgataataag gagaatcata ggtgttttct tatttgtttt
    34441 tttgataaat cttacaatta acatgattaa acctataata aataaaacaa taccagtaaa
    34501 accaaatata ccgtccatta atagatcctc tttctctttt gatattgaat attataaacc
    34561 aagcaattct tttttcttaa aatcgaattc ttcttgatta ataatccctt catctaacaa
    34621 ctctttatac tttttaattt catctgcact tgaaatttgt gtttctttgg aattattatc
    34681 taatatagat tgttgcttct ctatatattt ttttaaattt tccatttcat tccaatattt
    34741 ttttgtaaac ataacggtgt tttcatcttt cgtggccgct aatatacctc cgcgactttc
    34801 gtttccgcct agcaaggtaa attgtatata accattactc atacctggtt tttttaattg
    34861 tacggctgat atatttttaa aggggatagt tttttctcct ttaatacctt gattaactaa
    34921 atttataaat ccttttctaa taattgaaat agaatcatca gttactttaa tcaaggtttt
    34981 tcctggagat tttattaaaa tctctttttc cattttttct tcctcatttc tgtgatatga
    35041 ttttttttgt agaagctcat atatgaggaa agagcccgtg ttgcagcacg ggctttttta
    35101 atgttttgct gaaatcggtt tttttaataa ttcttgatgt attcatacat attgccttgc
    35161 gtaagaatat tttttcttaa aatagcattg gcagacagca taacaagtgt atctgagctt
    35221 attctgaata gaataatact ccataa
//
LOCUS       DBBGRF010000029        34812 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000029 DBBGRF010000000
VERSION     DBBGRF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.029"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(255..1103)
                     /locus_tag="ACIZD4_001586"
     CDS             complement(255..1103)
                     /locus_tag="ACIZD4_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC5990524.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1327..3267)
                     /gene="thrS"
                     /locus_tag="ACIZD4_001587"
     CDS             complement(1327..3267)
                     /gene="thrS"
                     /locus_tag="ACIZD4_001587"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGC5990525.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3604..3783)
                     /locus_tag="ACIZD4_001588"
     CDS             complement(3604..3783)
                     /locus_tag="ACIZD4_001588"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HGC5990526.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3830..5653)
                     /locus_tag="ACIZD4_001589"
     CDS             complement(3830..5653)
                     /locus_tag="ACIZD4_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC5990527.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5931..8210
                     /gene="helD"
                     /locus_tag="ACIZD4_001590"
     CDS             5931..8210
                     /gene="helD"
                     /locus_tag="ACIZD4_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HGC5990528.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8303..8950)
                     /locus_tag="ACIZD4_001591"
     CDS             complement(8303..8950)
                     /locus_tag="ACIZD4_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990529.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9129..9848)
                     /locus_tag="ACIZD4_001592"
     CDS             complement(9129..9848)
                     /locus_tag="ACIZD4_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5990530.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9979..11130)
                     /locus_tag="ACIZD4_001593"
     CDS             complement(9979..11130)
                     /locus_tag="ACIZD4_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGC5990531.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11347..12087)
                     /locus_tag="ACIZD4_001594"
     CDS             complement(11347..12087)
                     /locus_tag="ACIZD4_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC5990532.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12091..12414)
                     /gene="rsfS"
                     /locus_tag="ACIZD4_001595"
     CDS             complement(12091..12414)
                     /gene="rsfS"
                     /locus_tag="ACIZD4_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGC5990533.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12471..13064)
                     /gene="yqeK"
                     /locus_tag="ACIZD4_001596"
     CDS             complement(12471..13064)
                     /gene="yqeK"
                     /locus_tag="ACIZD4_001596"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGC5990534.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13048..13698)
                     /locus_tag="ACIZD4_001597"
     CDS             complement(13048..13698)
                     /locus_tag="ACIZD4_001597"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGC5990535.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13708..14019)
                     /gene="yhbY"
                     /locus_tag="ACIZD4_001598"
     CDS             complement(13708..14019)
                     /gene="yhbY"
                     /locus_tag="ACIZD4_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGC5990536.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14035..15144)
                     /gene="yqeH"
                     /locus_tag="ACIZD4_001599"
     CDS             complement(14035..15144)
                     /gene="yqeH"
                     /locus_tag="ACIZD4_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGC5990537.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15141..15668)
                     /locus_tag="ACIZD4_001600"
     CDS             complement(15141..15668)
                     /locus_tag="ACIZD4_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGC5990538.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15848..16633)
                     /locus_tag="ACIZD4_001601"
     CDS             complement(15848..16633)
                     /locus_tag="ACIZD4_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGC5990539.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16626..17495)
                     /gene="accD"
                     /locus_tag="ACIZD4_001602"
     CDS             complement(16626..17495)
                     /gene="accD"
                     /locus_tag="ACIZD4_001602"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGC5990540.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17496..18875)
                     /locus_tag="ACIZD4_001603"
     CDS             complement(17496..18875)
                     /locus_tag="ACIZD4_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGC5990541.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18883..19302)
                     /gene="fabZ"
                     /locus_tag="ACIZD4_001604"
     CDS             complement(18883..19302)
                     /gene="fabZ"
                     /locus_tag="ACIZD4_001604"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGC5990542.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19327..19803)
                     /gene="accB"
                     /locus_tag="ACIZD4_001605"
     CDS             complement(19327..19803)
                     /gene="accB"
                     /locus_tag="ACIZD4_001605"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGC5990543.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19806..21041)
                     /gene="fabF"
                     /locus_tag="ACIZD4_001606"
     CDS             complement(19806..21041)
                     /gene="fabF"
                     /locus_tag="ACIZD4_001606"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGC5990544.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21060..21797)
                     /gene="fabG"
                     /locus_tag="ACIZD4_001607"
     CDS             complement(21060..21797)
                     /gene="fabG"
                     /locus_tag="ACIZD4_001607"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGC5990545.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21809..22726)
                     /gene="fabD"
                     /locus_tag="ACIZD4_001608"
     CDS             complement(21809..22726)
                     /gene="fabD"
                     /locus_tag="ACIZD4_001608"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGC5990546.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22833..23057)
                     /locus_tag="ACIZD4_001609"
     CDS             complement(22833..23057)
                     /locus_tag="ACIZD4_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGC5990547.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(23110..24072)
                     /locus_tag="ACIZD4_001610"
     CDS             complement(23110..24072)
                     /locus_tag="ACIZD4_001610"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGC5990548.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(24082..24522)
                     /locus_tag="ACIZD4_001611"
     CDS             complement(24082..24522)
                     /locus_tag="ACIZD4_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC5990549.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24828..25793
                     /locus_tag="ACIZD4_001612"
     CDS             24828..25793
                     /locus_tag="ACIZD4_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGC5990550.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25850..26080)
                     /locus_tag="ACIZD4_001613"
     CDS             complement(25850..26080)
                     /locus_tag="ACIZD4_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HGC5990551.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26166..27053)
                     /locus_tag="ACIZD4_001614"
     CDS             complement(26166..27053)
                     /locus_tag="ACIZD4_001614"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC5990552.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(27142..28365)
                     /locus_tag="ACIZD4_001615"
     CDS             complement(27142..28365)
                     /locus_tag="ACIZD4_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGC5990553.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28382..29428)
                     /locus_tag="ACIZD4_001616"
     CDS             complement(28382..29428)
                     /locus_tag="ACIZD4_001616"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGC5990554.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29592..31319)
                     /gene="ptsP"
                     /locus_tag="ACIZD4_001617"
     CDS             complement(29592..31319)
                     /gene="ptsP"
                     /locus_tag="ACIZD4_001617"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGC5990555.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(31319..31585)
                     /locus_tag="ACIZD4_001618"
     CDS             complement(31319..31585)
                     /locus_tag="ACIZD4_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGC5990556.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            32064..34298
                     /locus_tag="ACIZD4_001619"
     CDS             32064..34298
                     /locus_tag="ACIZD4_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5990557.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34446..34766
                     /locus_tag="ACIZD4_001620"
     CDS             34446..34766
                     /locus_tag="ACIZD4_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGC5990558.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPQH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT         9855 a         7515 c         6064 g        11378 t
ORIGIN      
        1 acccaaaaac ttcttaataa aaaagaaaaa atgggcggag caagaaattc tttacctaat
       61 ttcaagataa aatcaacttt ttgtttcaca gcaatcactt aaagttacat atccaactat
      121 ttttttcatt aaaaaataaa cttatttttg aaaattatgt tttcttaagt cgtgaaacac
      181 tttgatggat catttatttg tggaaaacta cgttttgtta ttctaaaaaa cttatataaa
      241 aaatagtaag gtttttattt cgaatccata aaatattctt ggattgcttc tcgtgttttt
      301 ttcacttttt cgctaagctt ttcgttttta gccatataga aataaaaaat gatatcgatc
      361 gtagcaaatt gggccaaaag tgaattagtt gccgcacttc gattcgtgat ttcttttggt
      421 ctagatgttt gtacgagtac atcggctatc ttgctaagcg ggttatttcc aaattgcgtc
      481 aacgcaatga tttcgatatt catgcttttc gccagctcgg ctaatgcgac tacatctgca
      541 cttctacctg agtttgaaac aagccaaagc actttctttt tctcattgct gacaagttgc
      601 gggagcaaga cgtggatatc tttttcaaaa atgattggct taccgacacg agaccatttt
      661 tgcagaatat cttctactac taaagaagag gcgccaaccc catataaaaa aacagtctct
      721 gccgattcca aacactctac gactttttgg atcgtttctt cttctagaat atctactgtt
      781 tcttttatcg ctacttgtgc attgttacca agtttgtttt tgatagagta aaaggactca
      841 tttgcttcta tatcactaaa accttcatcg attccagtct gtagttctgt tgaaatcgtg
      901 attttgaagt ccgtcagact ttgaaaaccg atttttttgg aaaaacgtac aactgtcggc
      961 gcactcaacc cggaagcttc tgctaattca ttagctgtca ttgtagggac cttctcaata
     1021 ttaccgataa tgtagttggc caactttttt tctgctgaag aataatcttc catcatactt
     1081 tcaatacgac taattacgct cataagttcc tccacccttt taatgatagt ctatgtaagt
     1141 ataccatatc agacccttat tcacggtcgt atactggata aaaaacaaaa aaacaatccg
     1201 cccaacagaa tatcttatcc catcaatccc acagattcta ttgagcatct gtgtctttga
     1261 ggaatacctg ttatctattg ttcggattgc tttctatcta ctactttttt acaggaaatt
     1321 tacctattag ttttctctgc tgtaattttt gacttctgct tccatagcat caataaagat
     1381 attcaaatct tctacagctg tttctttact tccataacga cgtacgttca ctgttgcatc
     1441 ttccaattcc ttgtctccaa caactaattg gtaagggatc ttttgtgttt gagaggcacg
     1501 tatcttatag cccatttttt cattacgatc atcaacttct acacgcaacc ccttcatttg
     1561 caaacgttct ttgatttcat aagcataatc gccatgtgca tcaacagaaa cagggatgat
     1621 tgttgcttgt ataggtgcca accatgttgg aaaagcgcct ttgtatactt ctgttaaata
     1681 agcgacaaaa cgttccattg tagaaacaat tccgcggtgg ataactactg gacgatgcgt
     1741 attttccccg tcttctccaa catatgtcaa atcaaagcgc tctggcaata agaagtctaa
     1801 ttgtatagtt gataatgttt cttctgtacc aagagctgtt ttgacttgaa catctagttt
     1861 tggtccgtaa aaggctgcct cgccttctgc ttcaaagtaa tctagttcta attcatccat
     1921 agcggctttc agcattgctt gggctttttc ccacattgcg tcatcatcaa aatatttatc
     1981 tgtattgttt ggatcgcgat agctcaagcg gaaacgataa tctgtaatat tgaagtcagc
     2041 atatactgcc accatcaatt caagcgtacg tttaaattca tctttgattt gatcaggacg
     2101 aacaaatgta tgaccatcat tcaacgtcat ttctcgtaca cgttgtaaac ctgacaaagc
     2161 acctgatttt tcatagcgat gcatcattcc taattcagcg atacgaattg gtaattcacg
     2221 ataagaatgg atcgtgtttt tgtagaccat catgtgatga gggcagttca ttgggcgaag
     2281 aacaagcatt tcgccatctc ccatatccat tggcgggaac atgtcttctt gataatgatc
     2341 ccagtgtcca gatgttttgt acaactcaac atctcccatt attggtgtat atacatgttg
     2401 gtaacctaga ctaacttctt tgtctacgat ataacgttcg atcgtgcgtc ggattgttgc
     2461 cccttttgga agccagaatg gcaaaccaga acctacttct ggggaaacca tgaacaagtc
     2521 aagttctttt cctagtttac gatggtctct ttcttttgct tcttcacgga gacggatata
     2581 ttctttcaaa gctttcttgt caaaaaaggc tgtcccgtat acacgttgca tcatttgatt
     2641 gtttgagttt ccacgccaat aagcacctgc cactgataat aatttaaata cttgtatacg
     2701 gccagtggat ggaacatgtg gtccacgaca caaatcgatg aattcgcctt gttgataagc
     2761 agtaatcact tcttcttctg gcaattcact aatcagttct actttgtacg gatcacttgc
     2821 aaaaatttct aatgcttcct gttttgaaag aacacggcgt tcgatcggca gattttcttt
     2881 gacgattttc atcatttctg cttcgattgc cggcaaatct tctgcagtta cttggttttg
     2941 tccattatct gtatcgtagt aaaaccctga atcgatagct ggtccaacgc caaagtggat
     3001 atttggatag aggcgacgca tggcttgggc catcaaatga gctgctgaat gacggactaa
     3061 gccaagtgca tcttcatggt ctggtgtgat gatctcaata cttgcatctt cctcgattgg
     3121 acgagtcaaa tcaacgagtt ttccgttcac tttaccagct aaagcttttt ttgctaagct
     3181 ttttgaaatg ctttcagcaa ttgccaatgt tgttgttcca gactcaaatt ctttgactgc
     3241 accatctgga aaagtaattt ttatcataat agtttcctcc ttgaaatgtt ttgattgatc
     3301 agatcatcaa gctgaaaaac aaaaaaatcc tagcatctct tgaaaagaga tactaggacg
     3361 aaaagttcgt ggttccacct aatgttcaaa cgcaaatgcg ttcctcaagc gttgtaacgg
     3421 tccgaccgcc cttgcttcaa caagggtttc gaaagtggtc atcctttggt tttctcctgg
     3481 aaaagtttca gcctagcttt tcctctctta tcgaagactc tcaaattcag ttggctttct
     3541 catcaatcaa ttatgtgttt atttaaccac taataaatag aaaaatcaag tgggaaacta
     3601 aacttatttt ttccattccc catttacacc gtatgttcct tttttcatct cattgatgat
     3661 gacatggatg tgttcttttg gtgcctgcgt gtttttatga acagcttccg tgatatcttt
     3721 catcatattt tctaattgtt ccggactgcg accttctact aattcgacat gtacgaatgg
     3781 cataatgctc tctcctcttt ctgatcgttc ttttttcaac tcgattctat catactatgt
     3841 ttgtcttggg tactgaatca ggaaaaatgg ctggatcttt ttttgctctc aaggcactca
     3901 aaatagagac cgtatccacg acttcttgca aaacagctcc gaataatgcg gggattagtc
     3961 ccgtacttgc aattaacatc aaaaaaatac aaataaagat gccaatcagt acagactgtt
     4021 tcgctattct catcgtatct cttgaaatca ctactgcttt tgctacacgc aagagatcat
     4081 ctttcaagat gaccgcatct gcactttcac tagcagctgt agaaccatga gcccccattg
     4141 caataccgat atctgcagca gcaagtgctg gtgcgtcatt cacgccgtct cctaccatcg
     4201 caacaggtct ttgatcttta gggatacttt ctaaaatggt cagtttatct tgaggcaagc
     4261 tacgggcatg tacagaatct aattggactt tttctgcaat cgtttgagca atggcagatc
     4321 catccccggt gatcatcatc aaatttttca catcaagttt tcttagctcc ttgattgtct
     4381 ttgctgcttc tgggcgaatc tgatccgaaa ataggatcgt tcctgcaaaa gatcgatcaa
     4441 ttgttacata gattgctgta ttggacgttt ctatttcttc agctgaaaca aaagaggcac
     4501 gtccaatctt tacttcatga ttattgacta ctgcttggat tccttgaccg gtcacttctt
     4561 tcagttgact aacaggatac agttggctgt ttttcacgtt gttcactaac gaacgagcta
     4621 agatatggct agattcctgt tctgcactag ctgcatacag aagtagctct tcttttttta
     4681 ttccattgac tggctgaatc gcctctactt ccaatatccc tttggtaagc gttcctgttt
     4741 tatcaaaagc aatcgttttt gtacgtgcga gcttttcaat cgttgttcca gtttttacaa
     4801 cgatcccgtt tttacttgaa cggctcattc ctgcaactaa agcaatgggc gcagctagaa
     4861 tcagtggaca aggtgatgcc actaccagta cctcagcaaa tcgtaaaggg tcttttgaga
     4921 accaccaaga aataccaccg atcaaataag caatcaacgt gaaagggact gcataacgat
     4981 cagctaaacg gacaaatcgg gcaggctttt cttttgattc ttcgactagt ttaataatca
     5041 tttgatactg gctgtctgcg gcacgttttt cagcgatcat ttggatcgat ccgtctccat
     5101 ttaaagaccc tgacataatc tgatctccag gtttcttggt ttccgggcgg gactcacctg
     5161 tcaaagaaga ttcatcgacc gaagattctc ctttggtcac tcgaccatct gcgggtacaa
     5221 gttcgccagg cttgactagt aactggtcat caatatttat ttcatcgatt actatatcct
     5281 gcaattttcc ttctttgaat cgatgggcaa ttcttggggt gttatctaac aaagactgca
     5341 gttctttacc cgctcgttta ttcgcgtaat cctctagact atctccgccc gtaagcatga
     5401 tcaatatcat caaactagcc cagtattctt tgacggctaa tgttgcaagg attgcggtaa
     5461 tcgctaatac atctacgcca tatcttcctg aacgtaacgt cttgatcatt tccaaaaaca
     5521 tcaagaaggc gagaatccct ccagtaaatg cgacaatcgc aaatgcaagg gccggctggt
     5581 gaaaaacaaa ttcacttaat aaagctatcc caccaataag caaagtaagt aaaaattttt
     5641 tgaaatgtgt cattgttttt tctcctcttt tatgtgactt agagaggtta gtaataaatt
     5701 tccagctgcc tctttcatct taagcatagt ccttgactag cactttttaa aacaataggc
     5761 cttaattgaa aacaactatc actatcagcg tttccaaaat tcatcagttc tacaaacaaa
     5821 aatattcagc aaggattact ttttcgattc atcagttaaa aagtaccttt tttcgaaaaa
     5881 ctatgctata cttttaattc gttatttacg gcggaaggag caaacatgcg atgaatgaga
     5941 aacaactaga acaaacgcac gtggatgaaa cgatcgaact aatccagatc gaacaaaata
     6001 tgctggatac aaaacaacaa gaattgactc aggaaatgaa tcattcgaca aaagacacag
     6061 ctaatcacaa gattcgagct ggttccaatg aagcttttta tgaatctgct gttgaatatc
     6121 gccaacatga gcaggaattg cttttgaaat accatactct tgaagcacag caaaaacgcc
     6181 tgcaaacgtt gtctgtcatg aaagatagtc cttattttgc ccgtatcgac tttaaagaag
     6241 accgtgaaac agaaacatta tatctaggta tcgcttcttt aagagatctg gcagaagaaa
     6301 caatcgttat tgactggcgc gcaccaattg ccaatcttta ttatgaaggt gagattggtc
     6361 ccgcatttta tgaaactgaa acagatagaa tagatgtcga tctgcagttg aaacgacaat
     6421 ttaaaatcca agaaggacgt attttatcta tggtagatac gtcggaagta atcaatgatg
     6481 actttttgct agagatattg gatgaatcat caagcaacca tatgaaaaac atcgtctcta
     6541 cgatacaaaa agcacaaaat gcaatcattc gggacacaac aagtaaagta atgctgattg
     6601 aaggaatcgc cggaagtgga aagacatccg ctttgcttca acgtattgct tttctgttgt
     6661 atcataatcg caagtggctc gaggctgaaa acgttcttct attttcaccc aaccatttgt
     6721 tttctgatta catctcgact gtattgcctt cattaggtga aagcggcgtg cctacacaga
     6781 cattcaaaaa ttatttggtg cagctgctgc cagagttttc tttactagat gaacagcaac
     6841 aagaaagtgg ttttttgcta ggggaaaaag atccgataca agtgatgaaa agcggattga
     6901 ccttagtcga tcagattgat cgctatatcc aaggcatcac aaactacggt cccttgttcc
     6961 gtgatatgaa aataaatggc cgtacgatcc tatcaaagga atcgattcgc caatggtata
     7021 aagaaacaaa tgaacaatta cctttacatc atagactttc tctattacaa acgaagctcc
     7081 tgaaaaaatt aggcggtctg caaaaagacg aaacacgtca gcaatgggtc aaagatctgg
     7141 cggaagaaca gctccaagaa ctatacgcaa cagatccaaa tcttgaatat acagaacaaa
     7201 aggagcgttc attacgtaaa aaactggcca accaaatcgt acgtaaaaga ttccgtcgaa
     7261 tccatcgagg gatcatgaat tatcaatttg tcaatataac gaaacaatat ctccactttc
     7321 tacaaactgt gccactttct cttctaacac gacataaaat cagcgagacc aggtggcagg
     7381 aacatttgac aactgttcgt acacacttgc gtcaaagaga attgcgtcaa gaggatgctg
     7441 tactattctt tttactgatg cgccgaacat atccagtgac ggttacacac aaagctcgct
     7501 atatctttat tgatgaaatg caggatttcg caccatcaca agtggcattg ctgcaagcct
     7561 tgttcccaaa agcaaatttg actttctgtg gagatctaaa tcaaaatgtc tttggaaatg
     7621 aaacgatcgt tggatcattg gaagaccttt tcgtggaccg tgaagtcact cgtttccaat
     7681 taacgacaag ctatcgctcc acaaaagaaa tcactgattt tgctaatcat tttattgtga
     7741 aagaacatca agtagaaaca acagcaagaa aaggagacct tcctttgctc atccaaggaa
     7801 caacagatga tatcaaattg aattggttag cagataccat tcgaacgact cagggaaaag
     7861 cccggtattg gcgtacagca atcatagcta aaacacaaga agaatgcgaa gctctttatg
     7921 ctcaactgcc agacgagttg aaacaacaag tccagctgat tttaaatgag agtgacttta
     7981 tgaagcgttc cattatttta cttccagcct ttttagcaaa aggtctggag tttgaccgag
     8041 ttttcttgtg ggatgtagat gcagaacatt tttcttctca gcaagacaaa ttgatccttt
     8101 acaccatgtg tacacgtgcg atgcatgaat tgaccctttt tacctccaat aatgaaagtc
     8161 ctttgttaaa caatatggat atttcatctt atgagaaaaa agtactgtaa gtaaaaagac
     8221 aactgctatc attaatgtta gcagttgtct ttttatttac aataataatt gcagaaaaag
     8281 taattcaatc atttaaggtc atttattcta tatataaatc caaatctgtt tcaggatatt
     8341 ttaatttgac aagcgaaata atcattttca gttcttccat gttttctgga tattctgggt
     8401 caaatacctt gctatgacgg ccaatcccgc cattgtcgat caatcggtaa attcgattcc
     8461 attcaatgaa ttggtcaatt gattggaaat tgctgattgg atagccgcca caatccaaaa
     8521 tctctgatac acgaaatgct aggtatgcac tatcgatcac tttatttttt ttcgtgtcta
     8581 tcttctcatt tctttcgata agaatttttt caggacgatg tttcaagctc cactctaata
     8641 gtagaaagaa agcctccatc cgatactctt cttcaaataa ccgaaaggct gaatcagaac
     8701 gacgaaaaag cagcggaatc agataatttt gtctataaat cagcattggt gcgcggtcca
     8761 ccatacactc taaataacgg ttcagatacc ctgtaccgac atagtttcct aatcgatagc
     8821 cttcaacgcc gaatcttgcg tatttttgcg ctaattttga acaatcagtt acgttcacag
     8881 ctaactcttc tactttgcgg taaccgctta agatacgttc aaaaggttct aaagtgattt
     8941 ttgcttccat attcttcccc gtccatcttc cacatacttc atatcatttc acatgatact
     9001 tatgctctca tcataccaca ggttgaatta gaaaagaaaa taaatcacac aaaaaagcaa
     9061 gacaatctgt tagtgagatt gtcttgcttt tcgaaaaaga ctgaatactt ttcgttaaaa
     9121 ctggttgctt agtcttctaa tgccacatta tggaacacat gctgtacatc ttctagatct
     9181 tccagtgcat caatcatttt ttcaaatgtt tcttgatctt ctggagatag tgttacctcg
     9241 ttttgaggga tcatttggat ctcagcgatt gaaaaatcag tgattccttt ttcttttaat
     9301 gcttcttgta tactatggaa atccgctact tcaccgtaaa cgatgatttg tccttcttct
     9361 tccattacat cgcgaacatc gatgtctttt tccattaggt attcaaggat ctcgtcagcg
     9421 tcttctcctg caaaagcaaa gattgctgta ttgtcaaaca tgtaagaaac cgctccggaa
     9481 acacccatgt tcccgccatt tttcccaaat gctgcccgta cgtctgctgc tgttcgattc
     9541 acattgttcg tcaatgtatc aacaatcacc attgagccgc ttggtccaaa tccttcatag
     9601 cgcaattcag agtatgtttc atctcctgca ccttttgctt tttcgattgc tcggtcaata
     9661 atatgttttg gtacattata agttttagcg cgatcaatga cgaaacgtag tttttggttt
     9721 gcatgcggat caggatcacc tgattttgct gccgcgtaga tttcaatccc aaattttgca
     9781 taaatccggc tattattagc atctttagca gttttctttg ctacgatatt tgcccattta
     9841 cgtcccatat tttcacttcg ctttctgatt tgatagtttc ataacgcaaa aacgtcctgt
     9901 tccattatac ttgtgaatca cgattctgtg aagctttttt tctttcttcc ttcattcttc
     9961 tcatttttag tcaattatct atactcggat tgggatttgc ccgaaattct gttccggaat
    10021 attgcctccc aattgataga tttgatcact tctaactaac agttccgctt cttgtgcctc
    10081 tttttttccg attcgggaat aaatagaaat ctcttttttt tcttttaaga atcttcttcc
    10141 agcatcggta aatccaagta gtcgaagata atttttattt tgttggacag gaatctcttg
    10201 ctttttgata ttcagcaaga cataacaaga taatcgttgg atccgtgtcc atgtatatct
    10261 ttttgttttt acctttgaca caaaatcctc aaaactatca gcagttgcag ctgctgtttt
    10321 catgcgcgat tctattcctt cggtcatctg atagatatct gtcagttcca gcaaagtaga
    10381 agataacaac cgataacgca aatacggcca ataagattcc caagtctgca gcgaacaagt
    10441 tgaaagatct tcttctgtct gaggcggcac aagtccagct attctttttc cttcttctaa
    10501 cgcatggcga atggctgttg cactggctat cctctgatct gtgatgattt tttcatgata
    10561 gcctgcactt ttacgtcgga tcggatgtaa ttccataggg tggacatact tggcattttc
    10621 ctttgcataa cttaatccca agatatgatt tggcgaagaa aaatcaagcg taatatcggg
    10681 atacagactg cgaaaaacct cagtcatttt ttgcggataa ctatacgttt gatcagacag
    10741 ttcttgaaat gcctcttcta tcctatcttg attctcttgg acaaagcgtc cgaaactgct
    10801 gtaatcaaac gaagtctctt cttctgttcc aaaacacaaa ctgtcacagt ccagtgtttg
    10861 caagattttt actgcacctt tagcaaaata gtcagctgac tgaaccgccc attcgacggg
    10921 aagctccact actaaatcca caccattttg taaagcttca ttcgcgcgat gccatttatc
    10981 gatgatagcc ggttcgcctc tttgcaaaaa attcccgctc attacagcaa tgacgacctc
    11041 tgctcctgtt atttttcgtg ccatttccac atgatagcga tgtccattgt gaaaaggatt
    11101 gtactctacg ataatcccgc agcttttcat gcgcatcctc cttcatagtt atcgataaaa
    11161 aagaaataga gacaagtaaa aaaaggcaaa aatcggaaaa aatacccgaa ctatataaac
    11221 tattctcgca aacacaatac ttctgcgacg aaaagctgca ctgcaagagc aatgcctata
    11281 tcgttcggat atataattta tgttgaagat ttattctttt cttgttaact cgagcaggca
    11341 aaaccgctag tctttgtatg ctacaaagaa ccagcgcttt gatttctctg atgctgcttc
    11401 gtctgtaaaa tcagaaaatg cttcgacttt cgaaaagccg ctgttttcca gcattcttaa
    11461 ataactttcc aatggatagg tacgctcttg atgtagttca tcttcacgaa taaatcgacc
    11521 agacccttct tgttcttcaa cgaaaaaggt aagaaaatgt tcgatgctgt gtttctcgct
    11581 tcctggataa ctatcccaca aaaaagcaaa attatcccct tgataatgat agctatattc
    11641 tggaaaaacc tcatctactt gataggtgga gtgtacgtca aataaaaatc ggccattttc
    11701 ttctaacgct tgatagactt catcaaacac ttgctgtacc tcttgtctat ttttcatata
    11761 gcacagcgaa tcagaaaaac aggtaattgc ctgatattgt ccgatttctg ataaatcgag
    11821 catattgcct tccacaaatt ggatcgatgc gtcttcttca tatgctcgct ggctggcaat
    11881 catcaacatc tcttctgaaa ggtctaaccc tgtcacttta tatccatctt ttgcaaaggc
    11941 aaccgctaat gctccagtac cgcatgccag ttccaaaata ttttttgtgt cttcttgtaa
    12001 atgacgtttc gaaaaagcta accattgctg ataaagtgtt tcgtccatca cttcatcgta
    12061 aatgaaagca aatgtttcat aagccatatg ttaatccaac cattcactaa gatcgactag
    12121 cggagcatct gaccatagtt tttccagatt atagaaattt cgttctggcg catggaaaac
    12181 atgtacgatc acatctccaa gatcgatcaa tacccatttt ccgccttctt ttccttcaat
    12241 acgttttact tcatatttgt tttcttcttc tttatcaatg atttcttctg taattgcgtt
    12301 gatttgacgt tcgctatttg ctgaacagat catgaaataa tctgccaaca aggaaacatt
    12361 tcgaacgtct aaagcgataa tgtcttctgc ccgttttgaa tctgctgctt caatcgcaat
    12421 ttttaattgt tctttactat ctatgatgat ttcctcctaa tatgagcagc ttattttttt
    12481 gctacccagt aattatatgt ttcgattgtt tttggataaa tctgttgttc ttgcgcaagc
    12541 aaatgggcca atgtatgttt tgtttcaaat gctacagctt cgtctagatc agcccatgca
    12601 atggctcgtg catcttgtac cccaggaaaa tctcgacctg gttcaatata gtctgctaca
    12661 taaatgattt tgtcaaggag actcatctta gcagccccag tcgtatgcac ccggattgca
    12721 tgaagaatct ctgcatcggt gattcctaat tcccgctcta caaacgaagc gccaacaaga
    12781 ccatgccaga ttgcattatt ataattcaat aactccggat caaaaccgtc tcttacgatt
    12841 accattttga actcctcatc tggtcgttct tttgcataat catgtgtcaa tgcagcaata
    12901 ctagcttttt caggagaagc accgtatttt ttggcaagag ccacggctgt ttcttctact
    12961 ccaagcacat gcttgaagcg ttgttcgctc attctcatct gtattttttg catcaggttt
    13021 tctctagaat aagcagtata ttcattacta tagtccatat tcatacaacc cttcattttg
    13081 aatataatca attactttat ctggaacaag gtagcggata gaacagcctt ctttgatctt
    13141 ttgacgtatt ttcgtggaac tgatgtcgat ctcaggtaca tctacccaaa ttacaggata
    13201 tggagtatcc gttgtgtatc ctggtcgacg tatacccaca aagttgacca tagaagtcag
    13261 ctcatcgatt ttataccatt ttggcaaata ttctaccata tccccaccga taataaagta
    13321 ataatctgta tccggattgt tttgcgtcaa ttccttcata gtatcatagg tgtaactttt
    13381 cccaccacga gctaattcaa tcgtttcaat ctgcaaaaaa ggattgtctt ccaccgctaa
    13441 ttccaacatg ttgagtcgat gttttgcatc aatcgtctgt ttctcatcaa catgaggtgg
    13501 ctgataagaa ggcatcaaaa atacgcggtc aagacctaaa ttccggccag cttgttcagc
    13561 catcactaaa tgtgcaaggt gaacgggatt gaatgttccg cccaagatcc ctacttgctt
    13621 tttcttctct aagaattgag gcatttcttc aggaaataat tgtgaacgaa caaatgtctt
    13681 agcttgcgta ttcatcatgg tcactcctta tattgctttt acttcttttg atagcctttg
    13741 atacttttct tttgtggaag gtttgtataa tacaataaca cgtccaatga tttggacgat
    13801 ttcgcaatct atttcttttt ctaatacttg agctgcttct tctgcaatct catctgtatt
    13861 ttgaagtaac gatactttga tcagttctct tttttctaaa gcttcttcaa tttgaacgat
    13921 cattgctgaa ttgatcccac cttttccgat ttgaaaaatc ggctgaagat gatgcgcttt
    13981 gctacgtaaa aaacgctttt gttttcctct taaactcata attttccttc ttccttaaat
    14041 caatgctttg cgtttcaata catctacacc ctttggcgcc cagcccgcaa ttactactgg
    14101 cgctgttaca gtgatccagc ctagaccggc aaaaacgatg tctgtttttt ctttcacaga
    14161 aaactcaaaa cgaacaagct ccggaaatgc ctcgacttca tcaggacgag gaggctgtaa
    14221 taatccacct acatgttttt gataaaattc gtctgctttt tccagtttcg ttcgatgaat
    14281 atttacatca tttgacacat aagcaataaa tgaagcacga ttgccgctga taaaatcaaa
    14341 tcttgcaagt ccgcccaaga aaagtgtttg cccttcattc agctgataaa ctttaggttt
    14401 gatttctttt aacggtgcaa tgatccgcaa atctttttta cctaagtagt gcgccatttg
    14461 atggcgatgg ataattcccg gtgtatcaat caaaaaatgc ccgtcatcta aaggaatctc
    14521 gattttatcc aaggtcgttc ctggaaactg cgaagttgtg attacatctt gtactcccgc
    14581 tgtatttttg atgatttgat tgataagcgt cgattttccg acatttgtta ctccgacgat
    14641 atagacatcc cgtccatcgc ggtattcttc gattttttct aatagttccg tcatctcatg
    14701 agatttctta gcactagtta ataatacatc tactggacga attcctgctt cgtaagcacg
    14761 ttccttcatc cattgtgtta atttagtttt tttcaatgat ttaggtaata tatccacttt
    14821 gttcccaact aaaagtactg gattgtcacc gacaaaacgg tgtagtcctg ggattagtga
    14881 accattgaag tcaaaaatat ccaccacatt gacgatcaat gcatcttttt gccctaattc
    14941 attcagtaag cgcaaaaagt cgtcatccgt caatgagaca tcttgggtct cattataatg
    15001 gcgtaatctg aaacaacgct gacaatagac ttccccggaa gctaaacctt tttccaaagc
    15061 cgtttgcggc gtgtatccta attcaccggg tttgtttgtt tgtataacgg caccacagcc
    15121 gatacattgt aattcttctg tcattcgatt ccacctcgcc agcccatatc agggtgtttt
    15181 gctaatagat aggccataat tcttttttcc caaaaacgat taaattgtgt cttccaacta
    15241 tctgttgcga taatgggttt tacaaggatg ctacgtatcc ctgcacgatt ggctccacgt
    15301 atatcagtca taatctgatc gcctaccatt actatctcat catctgctaa atccaattgt
    15361 ttctttgcta tgttgatccc tcttgctaaa ggtttcattg ctcgtgcaac atacaaaaga
    15421 tcaaattttt caatcgctcg cgcgacacgt tttgaattat tgtttgaaac aacaacaaca
    15481 gggattcctg catttttcat ttctaaaatc caagtaagca actcttctgt tccatctgga
    15541 ttattccatg caatcaacgt attgtctaaa tcggtcaata ctgctttgat gcctagattc
    15601 tttaattggg caggtgtaat ctgatagatg gcttctacca tccatgttgg tttgtaattt
    15661 gaaaacatgc tgtctcctca tctgcaaaaa atgaaggagc acataaagta ctcctcaacc
    15721 ccgtattata ctgcatatca gcaaaaaaaa ctacctctat actcgttcgt ctttcagaaa
    15781 aagcatttct ttacaaaatg accaaaaata aagattgatc acagaaaaat ttagaaacaa
    15841 aaaacaacta atattggcgg aacctcttgt atcgtttttc cagtaattta tgctgatcta
    15901 atcgaacaag ttccgtcaat ctttcaatca acgctttttt cataatgtgt gcgactttat
    15961 atcgtggcaa ctgctcgccg ttgaacgttt caggaataac tcgatcaacg attcctaact
    16021 cgcgtagttc tggcgcagta attttcatca actcagctgc ttctgcggcg cgactaccgt
    16081 ctttccacaa aatcgacgca aatccttctg gagaaagcac agcataaatc gtttcttcca
    16141 gcatccagac ttcatccgct aaacctagag caagggcacc gccacttcca ccttcaccaa
    16201 tgatgatggc gatgatcggt acctttaaat cagacatttc gagcagattt ctggcaatag
    16261 cctctccttc gccgcgctct tctgctccta caccgcaata tgcacctgct gtattgatca
    16321 aggtaatcac cggtctattg aacttttccg cttgtttcat cagtcgtaaa gcttttcgat
    16381 agccttcagg atggggagaa ccaaaatttc tgcggatatt ttcctgcaga tcccgtcctt
    16441 tttgaatacc gatcactgtt accggtttgc catctaatcg agcgattcca ccaacaatcg
    16501 cttcgtcatc tgcaaataaa cgatcaccat ggcattcctc gaaagaatcg aagatctctt
    16561 caaaaaaatc caagcttgtc catcgttctt tagctcttgc taactgaacg acatcatgtg
    16621 ctgtcttatc cacgatctat ccatcctttc tgtgtatgca attcaagaag cgtatggatt
    16681 ttctgtttca attccatgcg gggaacaatc tgatcgacaa aaccatgaga taataagaat
    16741 tcagcctttt ggaaatcttc tggaagttcc tgcttgatcg tctgttcgat gacgcgtctt
    16801 ccagcaaaac cgatcaagct ttggggttct gctagaataa tatcgccttc cattgcaaaa
    16861 ctggcagtta ctcctccggt cgtcgggtcc gttaaaacag ttagataaaa aagaccttca
    16921 ttgctatgcc gtttgacagc agcagagatt tttgccatct gcattagaga aaagattcct
    16981 tcttgcatcc gtgcgccacc tgaagctgtg aacaagacga ctggaagact ttcctttgtt
    17041 gctcgttcga ataatctggt gatcttttct ccgacaatcg ttcccatact tcccatgata
    17101 aaattaggat ccatcactcc aataatgaag ggaatcccct gaatggttgc tttaccagtg
    17161 aggactgctt catgaagtcc tgttttatct tgcatttttt taattttttc cgtatattcg
    17221 ggaaatgcta gcggatcttt ggttacaaga tccgtatccc attcttcaaa acttttttca
    17281 tcaataatca aagctagacg ctgccatgca ccgattcgaa aagcgtatcc gcaatgaggg
    17341 catacttttt cttcaccgat gtctttcgta taaaggatat gtttgcaatt tggacacttt
    17401 gcccacatgt tatcaggaac agatggcgag ttagcaggtt tgctctctct attaggattg
    17461 atccgaatat atttcttttt cttaaacaga gccatctatg cgcctcctat ctccgtttct
    17521 ggtgtccaat tcggtaaaaa ttcttcttgt aaaaatgctg tgctgtaatc acctgctatg
    17581 actgcaggat gactaatcaa atccatctga aattctgcgt tcgtgatgat tccttctgtg
    17641 ataaattcac ttaaggctcg ctgcatcttc attaatgctt caaaacgcgt atttccatgg
    17701 acgattattt ttgcaatcat tgaatcataa tatggcggga tcgtatatcc cgggtaaact
    17761 gcactgtcta ctcgcagtcc catcccacct gctggaagca gtaagttttg gatcttccct
    17821 ggagaaggag caaaatggaa agcaggattt tctgcattaa tccggcattc gattgcgtgt
    17881 ccttggaata ctacttcttc ttgacacaca ttcaaaggct caccggctgc tatctccacc
    17941 tgttttttta ctaaatcgat tcctgtgacc atttctgtta ctggatgttc cacttggatt
    18001 cgagtattca tttccatgaa ataaaaatcg ccttcttcat ccatcagaaa ctcgatcgtt
    18061 ccggcatttt cataattgac tgctttagct gctcgaacag cagcgtctcc tagtgcttct
    18121 ctttttgttt gtgagatcac tacagaagga gattcttcca gtactttttg attgttgcgt
    18181 tgtaaagaac aatctcgctc gcctaaatga atgacatgac caaatcgatc acctaagatc
    18241 tgaacttcta tatggcgagc aggataaatg attttttcca aatacatatc atcatttcca
    18301 aatgccgctg ctgcttcttg ctgagctgaa gaaaaatgct gtgggagctc ttcttttgat
    18361 tgaactttcc gaatgccttt cccgccacca cctgcagctg ctttcagcat cactggataa
    18421 ccaattctgt ctgctatttc caatgcttct tctactgtag ataatacacc agtacttcct
    18481 ggaatgactg ggacatttgc ttcttgcatc aattgacgcg cattgatctt atttcccatt
    18541 gcatcgatcg ttgcactttt aggaccaata aatgtgatat tgcactcttc acacatggag
    18601 gcaaatcggc tattttcaga taaaaaacca aatcctggat gaattgcttc ggcttttgtc
    18661 acgattgcag cgctcagtac ttcctgaaca ttcagatatg aatcaacggc ttttgccggg
    18721 ccaatgcaga ttgcttcatc tgctaactgt gtatgaagtg cttcggcatc tgcttctgaa
    18781 tatatcgcta cggtttggat ccctagttcg cggcatgcac gaatgatacg tacagcgatt
    18841 tcaccgcggt tagctatcaa tactttagaa aacatatttc acctatccaa tcataaaggt
    18901 taattccgct tcggctactt ttttaccgtc tactttagcg attcctttgc ctattccggc
    18961 tgaagctttc actttcaata tctcaacttc aaggtataag gtatctcccg gtgtaacttt
    19021 cttacggaat tttgctttgt ccaatccgcc gaaataagcc gtctttccct tgaattgttc
    19081 aagagaaagt aatgcaactg ctcctgcttg agccattgct tcaacaatca atacccctgg
    19141 cataacaggt tcttctggaa aatgtccttg aaaaaagggc tcattgatcg ttacattttt
    19201 cttagcaacg atccgttctc cttcaaccat ttcttccact cgatcaatca aaagcattgg
    19261 ataacgatgt ggaatgattt cttttatttc ttgtatgttc attgttttcc ctctttcctg
    19321 ctttgcttat ttttgctgaa tcctaaagag tggctgtcca tattcgacaa ctgactcgtt
    19381 ttctacaagg atttctgtga tcactccgtc ggcctcacta gttatctcat tcatcagttt
    19441 catcgcttca ataatgcaga taacttctcc tttggcaact tgatcaccta cttttttgaa
    19501 agctggtttg tcgggcgctg gttgcagata aacgattccc acgattggcg aaacaacctc
    19561 gattccatca aatactgccg attctttttc tttcattatt tctggagcag ttgttgcttg
    19621 ttcaggtatg acattgactg gctccgaaac tggcaacgtt tcgtttgttt gaaccatatt
    19681 catgcctcga cttgttttat ttttattcat atacaattca aattgacctt cacgcaaatc
    19741 gaattccgtt agcgaggatt gatcaaattg actgactaat tctctgattt cattgatatc
    19801 caaaattatt cctcccagcg tttcatgcac agaaccgcat tatgtccgcc aaaccctaat
    19861 gaattactca ttgcataagt aaaacttgca ggtttgcttt cgtttttgac aactgtcaag
    19921 tcaatctcag gatcttgttt ttctacattg atcgtaggtg ggataaattg atgttctaat
    19981 gccagcaaag ttgccaaggc ttcgatcccg ccggctgctc ccaataaatg tccagtcatc
    20041 gatttcgtgc tgctgacgta agtatctctg aaattttcac ctaatgcgat ttggattgct
    20101 tttgcttctg cctggtcatt ggctggtgta cttgttccgt gagcattgat atatccgact
    20161 tgttccggct gtacaccagc ttcttccatc gcaagcttca ttgctttaga tgcaccagaa
    20221 ccatctggag taggagctgt catatggtaa gcgtcacagt ttgcaccgta tccaacgatt
    20281 tctccataga ttttggcacc gcgagcttgt gcatgttcta aagattcaag aactagaacg
    20341 cctgctcctt cacccatcac aaaaccattc cgattttcgt caaacggaat cgaaccacga
    20401 ttaggatcag ttgattctga gagtgctgtt aaagctgcaa atccagcaat ccccatctca
    20461 caaatcgttg cttctgttcc tccagcaaga atgacatcag aatagccatg tttgatgtta
    20521 cggaatgctt ccccaattga attcgttccg ctagcacaag ctgttacgat agctgtacaa
    20581 ataccttttg cacctacacg caaagcaata tttccagctg ccatgttggc aatcgccatt
    20641 ggtacgaaca ttggagaaac tcgttttgca cctttttcat gtagacgaat aacttggttt
    20701 tcgattgttg gaagaccacc gatcccagat ccgatgatga cgccaaaccg gtcttgattc
    20761 attttttctt tatctaaacc gctcatctcc attgcttcta aagcagcgta gattccatag
    20821 atcgaaaaca tatccattcg tttgctatct tttttaataa aatatttatc gtaagggaaa
    20881 tctttgactt cacccgctaa ggtaatccct gtttctgaag catcaaattt agtgatcggt
    20941 gcgatgccat tcgtcccctc ttttaagcta ttcaaaaagc tgtctgcgtc atttccaata
    21001 ggtgaagtga ctccatagcc agtaattacc actcgattca tttgtttgct ctccttttct
    21061 tatccgtgca tgaccaatcc gccatcgaca ttgatgactt gtccggtgat atatggattt
    21121 tgtgctaaga aaactgctgt ttgtgcaata tcttctactt gtccgaaacg ctgcatcgga
    21181 atttgctttt ccgcttgttc cttgactttg tctgctaaaa cttccgtcat atcagttgtg
    21241 atgaatcctg gcgcaatggc attacatgta atgcctctag ttgcagcttc tcgtgccaca
    21301 gattttgtta atcctactac gccagcttta ctagctgcat aatttgcttg accaatattt
    21361 ccaatcaacc cagatacact agagagatta atgatggccc cttctcgctg cttcatcatt
    21421 tttttcaata cgtgctgcgt catattgaag gttccaatca aattgatatc cagacatttt
    21481 ttgaaatctt ctgcatccat tcgcatcaca agtttgtcat ttgtgattcc ggcattgttt
    21541 actaacacat ggatcgatcc aagcttttct tctgcttctt tgatcatttg tcccgctttc
    21601 tcataatcag agatgtcacc ggaaactcct acgcatttta caccgaatgc ttcgatttct
    21661 tctatctttt cttttggaat ctctccgcga ccattcaaaa tgatatttgc tccagctttt
    21721 gcaaaagcta aggccatcgc tttgccgatt cctcttgtac tacctgtgat aaatacattt
    21781 tttcctttta catccataac gttcctcctt atagtattgc tattgtttca tcaaatgtct
    21841 gcttattctc aacacgcaga actggtattg ttttatcgat ttttttcata aatccgctta
    21901 atacttttcc ggggccgact tcgatgactt gttcgatgcc gattgttttt aacttatgga
    21961 tactctcata gaaacgaaca ggttgcatga cttgctgttc aagtagtccc gcgattgttt
    22021 ctttcttcat tatttccgtt gttgtgttgc ttatgatagg aaaagaaggt tcagagaatt
    22081 gaatctgact taggtccttc gccagttttt ttgctgccgg ttctaaaata gctgtatgaa
    22141 aaggcccgct gacatttaga gggatcattc ttttgaaccc tttttctttt aatagtaaaa
    22201 cagcttcgtc tactgctttt tcttcgccac caatcacgat ctgctgaggt gtattataat
    22261 ttgcaggaga tacgatgccg tacttgctag cttcatgaca gctttcctcg atcgtttcaa
    22321 tcggcgcatt catcactgca accattttcc cgcttccagc tggggcagct tctgtcatat
    22381 aagcgcctct ttttgctact aacgcaactg cttcagtgaa ggatagcgca ttactagcta
    22441 ctaatgccga atattctcct aaactcagtc ctaaagctgc atctgggatg attccatgct
    22501 ccttcaataa gcgataatac gcgatgctga ctgttagaat agctggctgt gtatattgcg
    22561 tctgatccaa acgttcattt tctgtaaagc aaagttcagc catatcgtag ccgagaatct
    22621 cacttgcttc atcaaatgtc tgctttacaa cggcttcttc atataaatct tttcccatac
    22681 cttgatattg tgcaccttgg ccactaaata agaatgctgt tttcatgttt ttctccaata
    22741 tatccagaat atatgtttga ttcttcctat tcaaaaaggc cgagacattc ctatttcagg
    22801 aaatgtccca gcccccaacc taattttaat gattatgcag tttgtttttc tacgtaagtc
    22861 actaaatctt gaaccgtttt gattccgtct tctgtttcga ttttcacgtc aaattcatct
    22921 tcaatttcat tgatgatttg gaataaatcc aagctgtcag cttctaagtc ttcttggatg
    22981 tcagtagtca atttgatttc ttcagtttct tttcctaatt cttctgcgat gatttcttga
    23041 attttttcga ataccataat aatatattcc tccgatattg tttgcttttt atttttataa
    23101 tttaacagtc tacaactcca tgagaatact tccccatgtt aaacctccgc catagcctgt
    23161 aaatattact ttctgctgtt ttcctaaggt gatctttcca ctagaaactg cttcatccaa
    23221 taagataggg atgcttgcag cagatgtatt cccatattta tccatattgg tcaggaactt
    23281 ttcttgcggc atctttactt ttcgggcaat tttctcaata attctgaggt ttgcctgatg
    23341 caaaagcaga taatcaactg gtttgtcttt catgacttct tggatattgt ttgcaacgtc
    23401 tcgtacggca aaatcaaaaa tatctctgcc agtcatttgc aaataatacg aaccttctga
    23461 atcttctgaa tagaacggat ttttattttg ctggtagcca gcggtcaatg agctacttct
    23521 ggtaccgtca gctgctaatt tttctttcag caattttttc tgtggattcg cttctaagag
    23581 aatcccacct gctccatcgc caaacaacac agcagtcgta cgatcagacc aatcgattag
    23641 cttagatagt gtttcaccac caatcaccag tcccttagtt gagccgcagc ggatcatttt
    23701 ttcagccatg cttaacgcat aaacaaatcc tgagcacgca gcactgatat caaaagcgat
    23761 agcatgagtt gctcccaatt tcccttgtac ttgtgctgct acagatggtg tcgtgtaatc
    23821 gggcgacatt gttgctacta aaataaaatc caaatcttta gggtttagat ttttctgttt
    23881 tatcaatttt tccgccacta aaatgcataa atcagaagtc tcctgatttg ttacacatct
    23941 tcgttcacga atacccgtcc ttgacgaaat ccattcatca gaggtatcca tcatcttgga
    24001 aagatcatta ttagtaataa tcttttcagg aaggacgctg gctgttgcag taatcattcc
    24061 aaattgttcc attaaatatc ctcacttata gtcttgcaag aagtcgtgca agtttttcag
    24121 tgcatccagc aaggcatgct gttcctccgt agccattccg tctaagatgt tcttgaccat
    24181 ttcacgatga aaatgctgat ggacccgaaa tagtaacttt ccttttttcg ttagtcccaa
    24241 ctttacaacg cggcggtcat cttcactgcg gatacgttcg acatagcctt tttttactaa
    24301 cttgttaata gcagtggtca aggtcccaac agtaattgat agttctttgg ctacttctga
    24361 agttgttttt ttcttgtaca tcccgattgc ctcgatcgtg tgcatctctg tgattgacag
    24421 atctttgaat tgagattttt tcagctcaga ctcttcgatt gtcaaaatat cattgaagac
    24481 actaacaaga taatcattta ctgtttttaa atctggttcc atgttccacc gtccactaat
    24541 tagtttgatt atcaaatctt ttgatgttca aactatatct taactttttt caaaatgcaa
    24601 ccttaaaaga tcattttttt actatatgag ctttttttaa gattttactc atttaaaaca
    24661 actgataaat cagcatttat aatttctttt attagaaaaa tcatctatct cacatatttt
    24721 gattatcaaa gtattttctg tgaacagaac tatagaattc cctaaaactt gtccattatt
    24781 tcaaaatttg ttatagtctt tttattcaaa gcgtaaaagg agatcctatg ttaaaagaaa
    24841 aaatgaaaac tctccccatg ctgccgggtg tctatcttat gaaagaccga gatggtaagg
    24901 tcatctatgt tggtaaagca aaacggctca aaaatagagt aagcagctat tttcatcaga
    24961 ataaacagca ttcaaaaaaa gtattacgta tgattcatca tataacagat tttgatttcg
    25021 tcgtagtaga cacggaatta gatgctttat tgctcgagtg tcaattgatc caacattacc
    25081 gtccttttta taaccgacaa atgaattatt tcagtaatta taattatgta catattacca
    25141 ataagggatt tgtattaaca gatactccta cggctcgaac atacgggcct tttcgtctct
    25201 ataaaaaaat gccgtctatt ttgcgtataa tggaagaaac ttatcaaatg ccttggttgt
    25261 ctgaaattag tttgttagct ttgcgagtcc agcttcctga cctacaggaa atgacttttg
    25321 aacagaaaaa aaaggaactc caagggctgt ttcaaggccg aaataaaaag ctactgactt
    25381 acttgaaaaa aagacaacaa catttcatct atcagttgaa tttcgaaaaa gccggtatgc
    25441 ttcaaaaaga tatcgaatta gttacttatt ttattagacg gatccaggaa caaaagcagt
    25501 ttttaagaac accatcgctc accttcagca tgccattagc agcagatgag agtcagaaaa
    25561 agcactacct cgtttgttat ggtcaacttg cagaaacaat gattacctct ggtgacgttt
    25621 ctcctgactt ctattatgaa aagaaagaag ctcatttatc tttgaaacgt caattgtcaa
    25681 aagaagaaat cgatcctgta caaatcttga tcagttaccg caaaaaatta gaaaaagaac
    25741 agtttgaaat tgaactgtta aacaaaaaag aagctgaaaa gcaactaaat tagttgcttc
    25801 tcggcttctt ttaggcatct tcaacttcaa atgtcaatta tcctaaaatt tattggatta
    25861 agtcatagat ttccatcgct acgatatcga tattatcaaa ttcgtattgc tgatgagtat
    25921 ctgtttcagt taattcaaat gtatcggtcg ctttatcata agttactgta cacttctcta
    25981 cgccttcttt ttcaaaacgg cgaacttgca gttcattatc tgctgactcg accatagcct
    26041 ccagtcgttt tatgattgcg actaattgtg aatgtgtcat cggaggtcct ccttttctta
    26101 tttctgttat attgtatcaa aagcatagcc tacttgcatt gattttctct aaaaaaactc
    26161 gttttttatg attttttttc tggtattttt ccttcaggcc accaaagttt gatcaaagct
    26221 tgggttccgt cattctcaaa acctttatct gccaactctt catatagttt caatgcttgg
    26281 gtagttgctg gcaatacaag atccattttt tctgcttctt ctaatgcaat ctttaaatct
    26341 ttgataaaat gtttgacaaa aaaaccaggt gtgtaatctt cttttaaaat acgaggagaa
    26401 taattgctta aagaccagtt agctgcactt ccacctgaaa gcgtctcaat cactttcttt
    26461 aaatcaagtc cgtttttttg tgcatagaca agcatttccg tcattcctgt catcgtacct
    26521 gcaatcatga tctgattagc catttttgta tgctgacctt tcccagcaga accatgcaat
    26581 gtaaatgtcg taccaaattc tttgaataaa ggcagtactt gatcataaac ggcttcttct
    26641 ccaccgacca tgatcgtcag tgtaccattc tttgctccta agtcaccacc ggataccggt
    26701 gcatctaacg catctgcgcc tttttctttt gctgtttttg caattttttc tgccaggctt
    26761 ggtgtacttg tagtcaaatc aactaaaata tgtcctgaga tatctgcaga aaaaatcccc
    26821 gactgtccat agtagatttc ttctacatct ttggggtaac ctaccattgt aaagagaata
    26881 ttactttgtt ctgctaccgc ttttggtgta tctgcccaga tagctccttc tgttactaaa
    26941 ggatcagctt ttgcttttgt ccgattatag acagctactt cgtgtcctgc ttctagtaga
    27001 tggcgtgcga cagcacttcc catgacgcct gttccgataa aaccaagttt cattttttcg
    27061 acctcctaaa aatcaaaaat ccttgcttct atgctagtat acgctagaaa caaggatttt
    27121 ttcataaaaa atgtttgaat tttatctttt aaatgaattt aattttattt tgattcgttc
    27181 aatcgagtct tcttcttctt ttcttcgcat ctcttcttca tgataaacaa ccatgtcttg
    27241 ataaaattcg atcatagctt cgccgaaatg tgtagatgaa atatcataaa gtttagcttc
    27301 taaaactttt ggatctttag gaacttcact ggaaatataa tcaataagtg ctggtgcaaa
    27361 gtcttcgtcg gtttcaaaag ttttccctaa tgaaggatga tcgaacaatc ggttcaaata
    27421 agcatttcct tccacgacac aaggtgttcc ggctgccatc gcttctgtat aagtaagccc
    27481 ttgtgtttct gaagtagaag cactgacaaa ataatctgcc gctttataat aaagtgctac
    27541 atcattgttg tccacttctc ctgtgaactg cacaaattct tctaactgca gttctgagat
    27601 caattcctct aactcttcta cataaggtcc ttttcctacg ataactaatc tggcgttagg
    27661 ataagcggag atgacctgag gaaacccatt aatcaaggct tggatatttt tctcataaga
    27721 aatcctgctt aaagaaagaa tcatcaaatg gttttcctga agacctagtg actcccttaa
    27781 tttgctgata tcctgctgag tgatatcaga acgtttgaat ttttcaatgt cgataccagt
    27841 aggaatcacg cgaagcggtg ctattacacc atagctgcgt aatgtatcaa taacacgttc
    27901 acttggacaa actacacctg tcgtatgatt tgcaaataat ctagacaagt attttacatg
    27961 ggattgcctg atcacttttc ctttaccgat ataatgaagg tagtcttcat acatcgtatg
    28021 gtaagtatgg atcagaggta ttttcaactt cttagctacc atcttcccaa gtatccctgc
    28081 tccgaattct gtatgggtat gaataagatc tagttctagt tctttggcaa ccaaataagc
    28141 ataccacatg cctctaacaa caactcttcg atccttgaaa gaaataaatg gtacacttgg
    28201 cattcgaatc acatcttttt ccaacttatc cgcattagga tcggtcgttg taaaaatata
    28261 gacttcatgc ccatgtcttt ctaattcttg ttttaatgtt ttgatcgatg tagcaactcc
    28321 gctgacttgc ggaaagtagg tatcggtaaa aaagccgatt ttcatgtttt tcgcctccaa
    28381 actagtcctt gacctgattt acttttttta atttgctaga gactttttca ttcagtacac
    28441 tttcgtatac atttttaagt tcttcaccga ttttattgat acttcgctct tttgctgttt
    28501 gataaccggc ttgtgtcgta ctcggtagtt cttgattggt aatctgttgg atcagtcgga
    28561 taaattcttc gtttgtcttc cccatatagc agttcttgct atcttctaac cagccattat
    28621 acactggaat atctcgaaca agtacgtttt gtttgcttgc taaagcttct aaaacaacga
    28681 tcccttctgt ctcttcataa gaagggaaaa agaatagatc tgcacctgaa tacgcacctt
    28741 ctatgatctc tccacgaatg taaccaggaa acaggacatt ttcaggatga tcttctttta
    28801 caattttccg gatgttccga ggaatcgagt acatgggaac atgaccaaac caaataaatg
    28861 tgtattcggg catcttctta gcaatttcta cgaaatcaat gattccttta cgttcgaaaa
    28921 acaaaccgac acaaatgatt actttttgat ccggagacag tttgaaatat tctctgaact
    28981 tttgttcttt cattggatca gggtgatatt tctctaagtc gatcccattg gaaatagctt
    29041 gaatcggcac acggatacca tagctttcca acaactgttt tgaataaggt gttggcgtga
    29101 tcagatagtc cgctttttgg tacaatccta ccagatattt ttttacgata ggagaaagct
    29161 ggttcgatcc gataaaggaa tttcggaaat cttcctctgt agaatgcgca tgatagacaa
    29221 ctttttttcc ttctcttctg gctttattga ccatattatg actattgatt ccgtatgtat
    29281 tgatgtgcag gatgtcataa tcttcttttt catctagtgt ataagagata ccgacttccg
    29341 tcagagcacg tttttgatga tcaagcgcac gcccgattcc agattttgca agcatctttt
    29401 cactttcaaa atataataat accttcacct tacgtccccc ttcacttata tagtataaca
    29461 tagcctacaa actgtcactc aaacttaagc cctatttttg tctattctta ctgacaaaaa
    29521 cgttttctta aaaaagaaca aaaaaactgg cgtagctctt ttacaagcca caccagcttt
    29581 tgatacgttg tttattttac atattcatga acaagttcaa cgacttcttc catcgtatcg
    29641 cattctttca atgcacgatc agcaagttca gccattttcg ctgtgtccaa gcgtttcatt
    29701 aaactacgcg ttttaagaat agatgtcgca ctcattgaga actcatctag acccatacct
    29761 actagcaatg gaacagctgt ttgatctcca gccatttctc cacacatacc tgcccatttt
    29821 ccttcagcgt gtgctgcatc aattacattt ttgatcaaac gtaaaattga tgggttatat
    29881 ggttggtaca agtaagaaac gcgttcgttc atacggtctg ctgccattgt gtattgaatc
    29941 aaatcgttcg tacctacaga gaagaaatct acttcttttg caaacttgtc tgctaagact
    30001 gctgctgctg gaatctcgat catgatgccg acttggatcg tatcagatac ttccttgcct
    30061 tcacttatca atttttgttt ttcttcttca aagatcgctt ttgctgcgcg gaattctttg
    30121 agtgtagcta ccatagggaa catgatacgt aaattaccat gaacagatgc acgaagcaat
    30181 gcacgcattt gtgtacggaa catttcgtcg ccttgttcag ataaactgat acgcaatgca
    30241 cgatatccta agaatggatt catttcatga ggtaattgca gatatggtag ttctttatct
    30301 ccaccgatgt ccattgtacg aacaactaca ggttttcctt ccataccttc taatacagct
    30361 ttgtaagctt catattggtc atcttctgtt gggaagtctg gagaatccat atacaggaat
    30421 tcagtacggt acagaccaac tgcttctcca ccattattat ggacaccaac tagatctttt
    30481 ggtgttccga tgtttgcagc taattcaaaa tgcttgccgt cagctgtgac agtttctgca
    30541 ttttttaatt tttcccattc tgctttttgt gctgcgtaat ctgcacctgc tttttcaaat
    30601 tcagcttttt gttcatctgt aggatcgatg attacatcgc cttcgatccc gttgacagcc
    30661 aaaatatcgc cttctttgac tttagcagta atttcttttg tcccaacgat tgctggaatt
    30721 tctaaagaac gtgccatgat agcagaatgt gaagtacgtc caccaatgtc tgttacaaac
    30781 gcttttacaa aattgcgatc taattgtgct gtatcacttg gagtcaagtc atgtgcaaca
    30841 acgaccactt cttcgttgat cattgatgga tttggtaaag taacgcctaa taagtgcgct
    30901 aaaatacgtt tagcaacgtc acgaatatct gcagcacgct cttgcatata agcattatct
    30961 tccattgctt cgaacatacc gatatacata tccgttactt cttttagcgc tgattcagca
    31021 tttacgctgt tgtctttaat attttgcttg atttgaccta ccatttctgg atctgaaaga
    31081 accatcaaat gggcatcaaa tacttgcgct tctgcttcac ctaagctttg cgctgctttt
    31141 tcacgaattt gctgcaattc ttcagtagat ttagctaatg cagcatccaa acgagcttct
    31201 tcagccgcag tatcttctac tgttgcctta ctgaatgtta aatccggttg aactagcagg
    31261 taagcttttg caacggctac accgtcacta gcggcaatcc cttttagcat ttcaaccatt
    31321 attcagataa gccttctttc ttcattgttt caacgattgc tgccattgca tcagcttcgt
    31381 cagcaccttc tgcagtaata gtaacatcag aaccttgacc tacacctaaa gacataacgc
    31441 ccatgattga tttcaagttt actgatttac ctttatactc taagtttaca tcagagttaa
    31501 atttgcttgc tgtttgtact aatagtgtag ctggacgagc gtggatccca gtttctgcta
    31561 ctacgtgaaa ttctttcttt tccatattaa tcggtctcct ttaagtgagt gttgttttta
    31621 tgtgagggtt ttctttttta gtaattcaga gaatcctaac aaatgccacc ctttcatctg
    31681 taaagattaa catttttttt cgttagatac aacagttttc attcaatttc agataaaagt
    31741 attcaaatta ttccggattc tttttcatcc ttttcttcac attttataac aaacgtgttt
    31801 atttcctttt tcttgtcgct ttctcttctc ctgacgttta tcattctttc ctttgaccct
    31861 ctttgttttc atatgaaacg aattacttgc ttcccttttt atttttagta taataagagt
    31921 caaaggtcag gaatggtcaa tagagatttc accttttcta cctcataaat ctcttaaaaa
    31981 actaggggtt attcttttac ctcatgaaaa acgagatgta aaatatggat gtacccattt
    32041 ttgtgaaagg acgtgaatga ttcatgcttt gtcaaaactg cggcaagaat gaggcaacga
    32101 ttcacttgta tgccactgtc aatggtcagc ggacacaact cgattactgt cagagctgtt
    32161 atcaaaaaat caaaaatcaa caaaatggag gtctgactaa tatggcccaa aatgatccat
    32221 ttggatttgg cagtttggac gatcttttcc gttccatgtc tcgccaaatg caacagcaag
    32281 gaaattatga gcaaacacca ccaacacaat ttggcggaaa caacaacttc aatggtggtc
    32341 agccacctca aggcaataca gaaggtttat tgggagaata cggaatcaat atcacagaac
    32401 aagcacgaca aggtgatatc gatcctgtga tcggacgcga tgacgaaatc aaacgagtca
    32461 ttgaaatttt aaatcgccga accaagaaca atcctgtctt gattggagaa ccaggtgttg
    32521 gtaaaacagc agttgttgaa ggtttagcac aaaaaatcgt agatggtgat gtaccgcaaa
    32581 aattaatgga caaagaagtc attcgtttag atgtcgtatc tttagtccaa ggtactggta
    32641 tacgaggaca atttgaagaa cgtatgcaaa aattgattga agagatccgt caagcagaaa
    32701 atgtgatcct attcatagat gaagttcacg aaatagtcgg tgctggttct gctggtgatg
    32761 gaaatatgga tgctggtaat attttaaaac cagctttagc tcgaggagaa ttgcaaatgg
    32821 ttggtgctac taccttaaat gagtaccgca tcatcgaaaa agacgctgct ttagaacgtc
    32881 gtatgcaacc tgtacgggta gatgaaccaa ctgtcgaaga aacgatcagt attttgaaag
    32941 gtttgcaaaa acgttatgaa gactatcatc atgtaaaata tactgatgag gccatcgaag
    33001 cagccgcaac tttatccaat cgttacgtcc aagatcgctt cttgccggat aaagccatcg
    33061 atttgctaga tgaaacaggt tctaagaaaa acttgacgat ccaaatcgtt gatcctaaaa
    33121 caatcgagaa aaaactgcaa gaagcagaag aacaaaaagt tttagcttct cgagaagaag
    33181 atttcgaaaa agcagcttat tatcgcgatc agatcaataa acttcaaaaa atgaaagaac
    33241 gtcagctcac tgaagaggaa acacctgtga ttaccgaaaa agatatggaa aaaatcgttg
    33301 aacaacggac aggtattcca gtgggtgaat taaaagaaaa agaacagaca caactgaaaa
    33361 acttagcaga tgacttgaaa gctcatgtca tcggacaaga taacgctgta gatcgagtag
    33421 cgaaagcgat tcgccgaaac cgtgttggat taaacaaaca gaatcgtcca atcggctcct
    33481 tcttatttgt tggaccaact ggtgtaggta aaacagagct tgcgaaacaa cttgcctacg
    33541 aactattcgg ttcacaagat tcaatgattc gtttcgatat gtctgaatat atggaaaaac
    33601 atagtgtctc taaattgatt ggttctcctc caggttatgt cggatacgaa gaagctggtc
    33661 aattaacaga aaaagtacgg agaaatcctt acagtcttgt cttgttagat gaagtagaaa
    33721 aagctcatcc agatgttttg catatgttct tgcaaatctt agatgatggt cgattgacag
    33781 atgcacaagg aagaacggtc agctttaaag atacgatcat cattatgaca agtaatgccg
    33841 gaactggtaa agtagaagca aacgttggtt ttggtgcggc acgcgaaggt gttactcgtt
    33901 ctgtattgaa ccaattaaac aactacttta caccagaatt tctgaaccgt tttgacggga
    33961 tcatcgaatt cagtgcatta tcaaaagaaa acttgatgac aatcgtcaca ctaatgctag
    34021 acgatgtcaa ccaaatgctg gcagcacagc aacttcacat cgaagttcct acgaatgtca
    34081 aagaaaaatt agttgactta ggctatgatc catctatggg tgctcgtcct cttcgacgca
    34141 cgatccaaga acaaatcgaa gatggtatcg ctgaatttta tcttgatcac ccttctatcc
    34201 atgagttgaa agcaaaactg gataaagatg gaaaaatcat cgttacttct aaaccagaac
    34261 gtttggctaa agaatcagcc gaagaaacgg ctgaataaat ccagttttat agcgtgagac
    34321 ggtatttctt tgagaaatgc cgtctcattc ttttttcaga aaagtcaaaa tactgttcat
    34381 tttataaaaa agaaattata ataagagaaa caagcaatta aaaatacata aaagaggtga
    34441 gcgccatgaa attggtaaat gtaacaaaca gccattcccg tcttgtatta aaccagcttg
    34501 aaaacactga tgcccatcta gtcaaggtct acacagccgg aaataccact attgtctaca
    34561 ctgaagcccc tcaacataat gaaattctgc tgatcaatga caaacgtaaa atccagccga
    34621 aagaaatcga agatgctaaa aattatttct tagataaaat caaagacgcc gtttaccacg
    34681 aggatgaaat caaagtaatc gaattggcag gccttgttga aatctcgatt ccaaaacatg
    34741 aattaggcgc tacattagcc gtgtaaacaa attttgaaca taataattaa agagcgtggg
    34801 acaaaagtaa ag
//
LOCUS       DBBGRF010000030        34688 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000030 DBBGRF010000000
VERSION     DBBGRF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.030"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            591..1280
                     /locus_tag="ACIZD4_001621"
     CDS             591..1280
                     /locus_tag="ACIZD4_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC5990559.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="ACIZD4_001622"
     CDS             1267..2475
                     /locus_tag="ACIZD4_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGC5990560.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="ACIZD4_001623"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="ACIZD4_001623"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGC5990561.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACIZD4_001624"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACIZD4_001624"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGC5990562.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="ACIZD4_001625"
     CDS             complement(6578..7273)
                     /locus_tag="ACIZD4_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGC5990563.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACIZD4_001626"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACIZD4_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGC5990564.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="ACIZD4_001627"
     CDS             complement(8472..8663)
                     /locus_tag="ACIZD4_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HGC5990565.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="ACIZD4_001628"
     CDS             complement(8684..9574)
                     /locus_tag="ACIZD4_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGC5990566.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="ACIZD4_001629"
     CDS             complement(9561..10328)
                     /locus_tag="ACIZD4_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HGC5990567.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACIZD4_001630"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACIZD4_001630"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGC5990568.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACIZD4_001631"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACIZD4_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGC5990569.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACIZD4_001632"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACIZD4_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGC5990570.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="ACIZD4_001633"
     CDS             14899..15282
                     /locus_tag="ACIZD4_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990571.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACIZD4_001634"
     CDS             complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACIZD4_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGC5990572.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="ACIZD4_001635"
     CDS             complement(16226..17044)
                     /locus_tag="ACIZD4_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HGC5990573.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACIZD4_001636"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACIZD4_001636"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGC5990574.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACIZD4_001637"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACIZD4_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGC5990575.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18173..19507
                     /gene="dnaA"
                     /locus_tag="ACIZD4_001638"
     CDS             18173..19507
                     /gene="dnaA"
                     /locus_tag="ACIZD4_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGC5990576.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19705..20835
                     /gene="dnaN"
                     /locus_tag="ACIZD4_001639"
     CDS             19705..20835
                     /gene="dnaN"
                     /locus_tag="ACIZD4_001639"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGC5990577.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21064..21306
                     /gene="yaaA"
                     /locus_tag="ACIZD4_001640"
     CDS             21064..21306
                     /gene="yaaA"
                     /locus_tag="ACIZD4_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGC5990578.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21293..22417
                     /gene="recF"
                     /locus_tag="ACIZD4_001641"
     CDS             21293..22417
                     /gene="recF"
                     /locus_tag="ACIZD4_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGC5990579.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22414..24360
                     /gene="gyrB"
                     /locus_tag="ACIZD4_001642"
     CDS             22414..24360
                     /gene="gyrB"
                     /locus_tag="ACIZD4_001642"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGC5990580.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24380..26851
                     /gene="gyrA"
                     /locus_tag="ACIZD4_001643"
     CDS             24380..26851
                     /gene="gyrA"
                     /locus_tag="ACIZD4_001643"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGC5990581.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27087..27386
                     /gene="rpsF"
                     /locus_tag="ACIZD4_001644"
     CDS             27087..27386
                     /gene="rpsF"
                     /locus_tag="ACIZD4_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGC5990582.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27436..27948
                     /gene="ssb"
                     /locus_tag="ACIZD4_001645"
     CDS             27436..27948
                     /gene="ssb"
                     /locus_tag="ACIZD4_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGC5990583.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27974..28210
                     /gene="rpsR"
                     /locus_tag="ACIZD4_001646"
     CDS             27974..28210
                     /gene="rpsR"
                     /locus_tag="ACIZD4_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGC5990584.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28353..30326
                     /locus_tag="ACIZD4_001647"
     CDS             28353..30326
                     /locus_tag="ACIZD4_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGC5990585.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30332..30784
                     /gene="rplI"
                     /locus_tag="ACIZD4_001648"
     CDS             30332..30784
                     /gene="rplI"
                     /locus_tag="ACIZD4_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGC5990586.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31058..32425
                     /gene="dnaB"
                     /locus_tag="ACIZD4_001649"
     CDS             31058..32425
                     /gene="dnaB"
                     /locus_tag="ACIZD4_001649"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGC5990587.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33205..34497
                     /locus_tag="ACIZD4_001650"
     CDS             33205..34497
                     /locus_tag="ACIZD4_001650"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGC5990588.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10563 a         6737 c         6861 g        10527 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgcggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gagtcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa tggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggtgatttc ctgtgtattc cgtctcctaa ctattggtat atctatattt
    17941 tttatccaca gatgcaagag gaaatctatt gatttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    18061 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    18121 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    18181 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18241 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18301 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18361 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18421 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18481 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18541 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18601 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18661 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18721 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18781 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18841 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18901 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgcctcgttt ctcgctttgc
    18961 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    19021 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    19081 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    19141 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    19201 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19261 ttatcacatc caattgaaag atatcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19321 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19381 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19441 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19501 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19561 aaaagttatg cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19621 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19681 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19741 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19801 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19861 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19921 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19981 tttactttag aagttttaga aaataaacaa gtagcgatta cttctggaaa agcgaatttt
    20041 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    20101 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    20161 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    20221 ttattggctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20281 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20341 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20401 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatcctga taccaatcgt
    20461 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20521 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20581 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20641 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20701 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20761 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20821 gtacgtacaa attaacaatg attttcattg ttcttgaaaa tttaattgaa aagaaataga
    20881 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20941 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    21001 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    21061 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    21121 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    21181 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21241 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21301 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21361 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21421 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21481 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21541 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacaaaaaaa
    21601 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21661 agtaaaaggc agcccgcaga tcaggcggaa gtttttagat atggaattag gccagatcaa
    21721 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21781 tttaaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21841 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21901 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21961 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    22021 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    22081 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    22141 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    22201 taaagaagag acgggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22261 tgatagtcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22321 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22381 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22441 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22501 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22561 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22621 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22681 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22741 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22801 gttgttaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22861 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22921 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22981 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    23041 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    23101 ggcgggatta aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    23161 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    23221 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggcgga
    23281 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23341 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23401 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23461 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23521 ttcttgctgg aaaacccaag tgtgggccgt caaattgttg aaaaaggatt actagcttcc
    23581 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23641 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23701 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23761 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23821 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23881 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23941 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    24001 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    24061 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    24121 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    24181 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24241 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24301 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24361 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24421 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24481 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24541 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24601 catgggtaaa taccatcctc atggagacta tgcgatctat gagtcaatgg tacggatggc
    24661 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24721 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24781 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24841 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24901 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24961 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    25021 tggaccagat tttccaacag gtggtttggt tatgggaaaa tcaggaatcc gaagagcgta
    25081 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    25141 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    25201 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25261 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25321 tgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25381 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaattc ttgaaaacta
    25441 tatcgaacat cagcgcgaag tcatcacaag acggacagtc tttgaaaaag aaaaagcaga
    25501 agcaagggca cacattttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25561 tgcgattatc cgcgggtcta aatcagatga cgaagcaaaa gcgacgatga tcgaacggtt
    25621 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25681 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25741 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25801 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25861 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25921 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25981 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    26041 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    26101 tccagaatac gggcgcacag ccaaaggaat accaattatc aatttactag gtatcgattc
    26161 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    26221 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26281 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26341 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26401 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggttagag gaatacgcct
    26461 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaagatcaag aagtattagt
    26521 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26581 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26641 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26701 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26761 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26821 aacagttgaa gaacaaggat cagaagaata gccatcaaga ctaattgtgt aagctagcaa
    26881 gaatgaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26941 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatca
    27001 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    27061 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    27121 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    27181 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27241 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27301 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27361 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27421 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27481 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27541 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27601 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27661 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27721 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27781 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27841 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27901 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27961 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    28021 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    28081 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    28141 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    28201 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28261 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28321 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28381 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28441 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28501 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28561 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28621 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28681 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28741 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28801 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28861 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattggatg
    28921 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28981 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    29041 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    29101 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    29161 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    29221 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29281 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29341 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29401 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29461 tcgttatcaa cgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29521 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29581 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29641 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29701 caagtaaacc tctgctgact tatatcgaat cttcagcttc ttcagcttca gagctagttt
    29761 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29821 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29881 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29941 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    30001 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    30061 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    30121 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    30181 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30241 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30301 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30361 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30421 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30481 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30541 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30601 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30661 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30721 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30781 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30841 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30901 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30961 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    31021 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    31081 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    31141 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    31201 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31261 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31321 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31381 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31441 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31501 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31561 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31621 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31681 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31741 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31801 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31861 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31921 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31981 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    32041 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    32101 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    32161 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    32221 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32281 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32341 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32401 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32461 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32521 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32581 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32641 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32701 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32761 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32821 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32881 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32941 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    33001 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    33061 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    33121 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    33181 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33241 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33301 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33361 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33421 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33481 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33541 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33601 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33661 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33721 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33781 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33841 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33901 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33961 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    34021 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    34081 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    34141 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    34201 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34261 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34321 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34381 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34441 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34501 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34561 gataataata acttgaagag gtagtgaaag agacgtttag ccttattgcc gataggctgt
    34621 ctcttgaaca ctgtttattc agaataaggg actgtgacaa aaaccgtgtc acagtccctt
    34681 tttccgaa
//
LOCUS       DBBGRF010000031        33263 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000031 DBBGRF010000000
VERSION     DBBGRF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.031"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(41..229)
                     /gene="rpmB"
                     /locus_tag="ACIZD4_001651"
     CDS             complement(41..229)
                     /gene="rpmB"
                     /locus_tag="ACIZD4_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGC5990589.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="ACIZD4_001652"
     CDS             499..861
                     /locus_tag="ACIZD4_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC5990590.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="ACIZD4_001653"
     CDS             913..2595
                     /locus_tag="ACIZD4_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGC5990591.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="ACIZD4_001654"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="ACIZD4_001654"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGC5990592.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="ACIZD4_001655"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="ACIZD4_001655"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGC5990593.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="ACIZD4_001656"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="ACIZD4_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGC5990594.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="ACIZD4_001657"
     CDS             6430..7434
                     /locus_tag="ACIZD4_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990595.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="ACIZD4_001658"
     CDS             7435..8379
                     /locus_tag="ACIZD4_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990596.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /gene="opp4B"
                     /locus_tag="ACIZD4_001659"
     CDS             8379..9341
                     /gene="opp4B"
                     /locus_tag="ACIZD4_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HGC5990597.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="ACIZD4_001660"
     CDS             9368..10282
                     /locus_tag="ACIZD4_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990598.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="ACIZD4_001661"
     CDS             10308..12089
                     /locus_tag="ACIZD4_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC5990599.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /gene="rnc"
                     /locus_tag="ACIZD4_001662"
     CDS             12437..13123
                     /gene="rnc"
                     /locus_tag="ACIZD4_001662"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGC5990600.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="ACIZD4_001663"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="ACIZD4_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGC5990601.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="ACIZD4_001664"
     CDS             16733..17542
                     /locus_tag="ACIZD4_001664"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC5990602.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="ACIZD4_001665"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="ACIZD4_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGC5990603.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="ACIZD4_001666"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="ACIZD4_001666"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HGC5990604.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="ACIZD4_001667"
     CDS             complement(21094..21546)
                     /locus_tag="ACIZD4_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGC5990605.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="ACIZD4_001668"
     CDS             21696..22646
                     /locus_tag="ACIZD4_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGC5990606.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="ACIZD4_001669"
     CDS             22639..23598
                     /locus_tag="ACIZD4_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGC5990607.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="ACIZD4_001670"
     CDS             23595..24350
                     /locus_tag="ACIZD4_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990608.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="ACIZD4_001671"
     CDS             24373..25326
                     /locus_tag="ACIZD4_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC5990609.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="ACIZD4_001672"
     CDS             complement(25970..26266)
                     /locus_tag="ACIZD4_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HGC5990610.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="ACIZD4_001673"
     CDS             26621..26977
                     /locus_tag="ACIZD4_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HGC5990611.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="ACIZD4_001674"
     CDS             26987..27886
                     /locus_tag="ACIZD4_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC5990612.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28406..29134
                     /locus_tag="ACIZD4_001675"
     CDS             28406..29134
                     /locus_tag="ACIZD4_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HGC5990613.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="ACIZD4_001676"
     CDS             29279..31306
                     /locus_tag="ACIZD4_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGC5990614.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="ACIZD4_001677"
     CDS             31414..32511
                     /locus_tag="ACIZD4_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HGC5990615.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33263
                     /locus_tag="ACIZD4_001678"
     CDS             32818..>33263
                     /locus_tag="ACIZD4_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990616.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11138 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaagagaaa gtt
//
LOCUS       DBBGRF010000032        32082 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000032 DBBGRF010000000
VERSION     DBBGRF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.032"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..189
                     /locus_tag="ACIZD4_001679"
     CDS             <1..189
                     /locus_tag="ACIZD4_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC5990617.1"
                     /translation="NSNGILRRNGLPKSIDFREVNQTFISSVSNQRNHIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
     gene            complement(1055..1480)
                     /locus_tag="ACIZD4_001680"
     CDS             complement(1055..1480)
                     /locus_tag="ACIZD4_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HGC5990618.1"
                     /translation="MHRKVRITRKSRGKIEIVLQSGKIVYLGFPVLNTAGNEETIISI
                     EGILRIQGPAFIAQGAHIDIRKNAVLDIGSKFNSTGKMSIICFKEIQFKDGCTVSWDT
                     LFMDTDSHTIFELNTHRILNKNNKIVIGKHCWIGAKSVI"
     gene            complement(1582..2199)
                     /locus_tag="ACIZD4_001681"
     CDS             complement(1582..2199)
                     /locus_tag="ACIZD4_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGC5990619.1"
                     /translation="MIIVIAEIITDILYKLYEPFGFAVLLTILGLVYFMYATDGIAAG
                     EGYKRILMELYLHLKKDRKYRKVCALIFYTAMILFTTLINRTIWLNPLSDVMGDWWIY
                     KYNTTTGTKELSTACLENIILFIPYVYMVMSIKYENIKKPKIWSSIVYGGKIAFYFSA
                     IIEFLQLFLRLGTFQISDFVYNTLGGILGVILYKLILITKRDGER"
     gene            complement(2781..3002)
                     /locus_tag="ACIZD4_001682"
     CDS             complement(2781..3002)
                     /locus_tag="ACIZD4_001682"
                     /inference="COORDINATES: protein motif:HMM:NF012360.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HGC5990620.1"
                     /translation="MGSSERIKIGNNVFIGMKSRILKGVHIGNNVVIGANSLVNKDVS
                     DDCVVAGNLAKVIMSLDEYYKKINNMKNP"
     gene            complement(3180..4712)
                     /locus_tag="ACIZD4_001683"
     CDS             complement(3180..4712)
                     /locus_tag="ACIZD4_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGC5990621.1"
                     /translation="MIINRKQNAKRNIITGTIFKLYQIIIPFFMRTLMIYQMGMEYAG
                     LNNLFTSIFQMLNLAELGIGAALTVSMYKPIAEDNRKEICALLNAYKKYFSIIGWIVF
                     TLGLLCIPFLRFLVKGSIPGNLNMTVLYLMYLINTVLSYWLFSYRKSLIYAHQRNDVI
                     NVSMLITFTFQFVMQAYVLIFLKNYYLYLLASILGQIVLNLMCAVVSQKMYPDYTPVG
                     ELEKETIDDIIKKVKGLVTNKVGGTILRSSDSIIISSFLGLSVLAIYQNYYFIISAIM
                     SIFAIIYESCIAGIGNSLIVESQEKNYIDFCDITTIIGWFLAISCACFITLFQPFMII
                     WVGSDNLMSISFVIFMIVHFFLYEIDQLIGLYKDAAGIWYADRFRPLITAMINIVLNI
                     ILVNWFGLYGVLAATIVSVLLVDLPWLLYNVFQNIFKFESAGKYVWKLISLCVIAFVA
                     SYLSYFACSYVNIGNFKVISLVINLVISVVISILVILLFNIRNKKFKYILKVLTSVLV
                     KR"
     gene            complement(4848..5933)
                     /locus_tag="ACIZD4_001684"
     CDS             complement(4848..5933)
                     /locus_tag="ACIZD4_001684"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGC5990622.1"
                     /translation="MKKICFISGVISRSGGTERVGSIIANSLSDLGYDVTILSFWNSG
                     EPYFGLDKTIKVDYMLNPKTEGKLYRTYLYPVWKLHKYICKNEFDIVIDIDTLLSLYT
                     TRAIKGTKCKLISWEHFNYWTMEMLKEKKRFKAKKLIKKYAKRLVVLTEEDRQKHIDE
                     YSLSEDFVITMPNPCISNIEYEYHYDKKRFLAVGRLVEEKNFADMISAWKIVEKKVDD
                     WDLIIVGKGELEKDLRQQIKDLNLQRVTIAGHSDHVEEYYKSASCYVLSSVYEGFPMV
                     ILEAQSYGLPVISYDCKTGPRDLVHHNFNGMLVEDKNIDQLAKSMIMFTKNTDLAMRM
                     SLNAYNNVQKFNLKEITKQWVALIENV"
     gene            complement(5948..6667)
                     /locus_tag="ACIZD4_001685"
     CDS             complement(5948..6667)
                     /locus_tag="ACIZD4_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 32 protein"
                     /protein_id="HGC5990623.1"
                     /translation="MIPKKIHYCWFGGNPLPKKDRKCIESWKKYCPDYEIIEWNESNY
                     DLNKNRYMADAYKERKWGFVPDYARFDIIYNHGGFYLDTDVELIKSLDILRENHAYMG
                     FEGEIWVNGGIGFGAEEGHSVIKGLRDIYDSLSFYQNDGTLNLKPSPYYITDYLESIG
                     LVRDNSEQIINGLHIYPTDYFAAKDYDTGKIYKTSNTISIHQYNASWKTPKQKFVYRL
                     KSTIGQKKFNRLLALKKFLHL"
     gene            complement(6664..7974)
                     /locus_tag="ACIZD4_001686"
     CDS             complement(6664..7974)
                     /locus_tag="ACIZD4_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGC5990624.1"
                     /translation="MRISIKRWSGADWTLFTLAFFAISIVLVYTFNAPRAILYLGDII
                     NIFVLLNALSFRRRKGIYASKNEMLIVLFLLVSICSSVINLENIGLIIWGIRNNTRMF
                     IVYINCATYLTIKDYYKVFAIIEKLFWISLPLCLIERFMVTYPTGTIVGDMIGGVFWN
                     YSGCNMPLNLILCVTVTVVTIGYFKGEKNFIHFILCVCAALFMSALAELKVFIPELFI
                     IFVAIVFTLKVDFKVVIKILSCVILVSIVLSFFITIFITLNDNGQSYADNFTIQGLLE
                     YASRDSGYDGVGDLNRITGISRVVDEIFNNNFRLVLMGVGIGNAEFTNFFVSEFYKSF
                     GNLHYQYFHHIWLFIEVGILGVSIFLFFIIKTFFNAKRSFMKDKDASLVKVIAIMSVF
                     FFVYNTTLRGETTGPLIYMILAMPEVVKRKEHYYSEKNTKGEIL"
     gene            complement(8001..8591)
                     /locus_tag="ACIZD4_001687"
     CDS             complement(8001..8591)
                     /locus_tag="ACIZD4_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGC5990625.1"
                     /translation="MEISSKEYLKAVLRMEKNLYIESKGQHTKLLKIMKSHPDYNAWR
                     YTRRMRITSYYYSKRKKNIIYAIMYIVSCRRMNSLGRKCGIECGENVFDEGVRFYHTQ
                     GIVINGNAIIGKNCYLYGNNCIGNDGIDPKCPVIGNNVRVCVGAKIIGNVKIANNVVV
                     AAGAIVIKDCLENGAILAGVPAKIIGYVNLTKVFLE"
     gene            complement(8909..9970)
                     /locus_tag="ACIZD4_001688"
     CDS             complement(8909..9970)
                     /locus_tag="ACIZD4_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGC5990626.1"
                     /translation="MNSSDLISVIIPVYNVEKYVGSCLESVCNQTYKNLDIIIVDDGS
                     KDSSNKICEDYALKDSRIRIIHKNNAGLGLARNTGLEHVKGKYVAFIDSDDFVAANYI
                     EAMLNGIKRSNADTCYAGYYEYYDDNNIISKPARYDSTIFTNNAIIEKVLLGMIGTEP
                     SYKVDFILPMSVWHALYSSEIIQQHNIKFPSERDYISEDIIFHISYLQHSKITSFIKD
                     CIYYYRCNNNNSLTHNFRDNEFDCNIELVKKIEGDLSYILENEIFVNKTRRLLLGRCR
                     TCIQKAVRYASFNKEFDLNSYLSKILMNDELIACIHSYPYKQNPIKQRIFNYFLLNQS
                     IIGVKTLAYLSGMGRNRRF"
     gene            complement(10538..11605)
                     /locus_tag="ACIZD4_001689"
     CDS             complement(10538..11605)
                     /locus_tag="ACIZD4_001689"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGC5990627.1"
                     /translation="MQRVLMIGNDSSVKGGITSIITQMLNFNWEKKNIEMTFIPSYKG
                     GNAIFKSLYFMYAFAKIIGISLLSKPNIIHMHMSYRGSFSRKYVLNKWFRLLNIPVII
                     HLHGSEFKKWYDSVSVKKQNQIRLLLRESDSTIVLGEKWKKIIKEIEPNCKTVVVENS
                     IVVPEYTIKWNSKMCRFLFMGVLIKRKGVHDLVEAVKNIAEQYPEKKFIFEIAGAGDE
                     EISLKELIEEYNLQSYFEFTGWVVGEKKEECYRRSNVMILPSYNEGLPISILEAISYG
                     MPVIATDVGDISSAVRDGENGYLFQPGDVSALTSAILKINDKDKYVKFSRCSKDLAIT
                     KFNDGNFFDRILNLYQKGSKE"
     gene            complement(11625..12104)
                     /gene="pssE"
                     /locus_tag="ACIZD4_001690"
     CDS             complement(11625..12104)
                     /gene="pssE"
                     /locus_tag="ACIZD4_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssE/Cps14G family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HGC5990628.1"
                     /translation="MIFITLGSQKFQFDRLLKAIDDLIEKGVIIESTFAQSGYSDYKP
                     LNYSYKAFLNRDEFTETMQKAEMVITHGGTGAIIGAVKKGKRVIAVPRLAKYGEHVDD
                     HQLQLIRQFDEMNIIYPCYELENLEDAVKETRVRMFNKYVSNTETIINSIEVLIEKI"
     gene            complement(12121..12582)
                     /gene="pssD"
                     /locus_tag="ACIZD4_001691"
     CDS             complement(12121..12582)
                     /gene="pssD"
                     /locus_tag="ACIZD4_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssD/Cps14F family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HGC5990629.1"
                     /translation="MNKKICFAASSGGHYEQLMMLKPLMEKYESFVITEQTEYSAESK
                     GEKTYYMRQVNRKEKFFLCTILINLFKSIIIYIKEKPDLVICTGVLAMIPICLITKMM
                     GKKLIYIESFAKVTSPTQTGKLMYHFADQFYVQWETMLQFYPNAIYLGGIY"
     gene            complement(12596..13846)
                     /locus_tag="ACIZD4_001692"
     CDS             complement(12596..13846)
                     /locus_tag="ACIZD4_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGC5990630.1"
                     /translation="MKKKYNIAVAGTGYVGLSIATLLAQHHQVTAVDIIPEKIELINK
                     RKSPIQDEYIEKYLTEKELDLTATLDARSAYKSADFVVIATPTNYDSRTQHFDTSAVE
                     SVIEVVMDVNPDTIMVIKSTIPVGYTESVRETTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMTDERLLNAAHVFATLLQKSAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPGNLIEAIVESNRTRKDFIADRVLQMAGYYNYAEYNQYDVNRENPVLIGIYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPALKDGETFFGSKVINDLEQFKAMCDSII
                     ANRYDTCLDDIKEKVYTRDIFQRD"
     gene            complement(14224..15675)
                     /locus_tag="ACIZD4_001693"
     CDS             complement(14224..15675)
                     /locus_tag="ACIZD4_001693"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGC5990631.1"
                     /translation="MYKKSSRGWVKHIDFIILDLLCIQLAFYLSYVLRQVDWNPYVIP
                     MYQNMAVFIELADLLVIFMFEAYRGVLKRGYYIEFASSVKQAIMLVLLGSLYLISVQG
                     GNDYSRVVLFLMGGLYVVITYITRLLWKHYLKHKMKNEGNKSLIIVTSSSIAEVVIRN
                     VKEHNYKMYKINGVIIIDKSMIGEDVEGVTVVSDSKNAADYLCQGWVDEVFIILNKST
                     SCMKEFIERCSEMGLTVHLNLAKVSDSALGKQSIGRIGEYTVLTTSINVMTTQQAFIK
                     RTIDILAGIVGCIATGIIFIFIAPLIYINSPGPIFFAQERIGQNGKPFKMYKFRSMYM
                     DAEERKVELMKENKMSNNLMFKMEFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FFNVLTGKMSLIGFRPCLKSEYEEYDYHHRARIAIKPGITGMWQVSGRSDITDFEEVA
                     KLDTEYIKNWSMGLDFKILFKTVKTVLQRGGSM"
     gene            complement(15996..16760)
                     /locus_tag="ACIZD4_001694"
     CDS             complement(15996..16760)
                     /locus_tag="ACIZD4_001694"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HGC5990632.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNVHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(16788..17486)
                     /locus_tag="ACIZD4_001695"
     CDS             complement(16788..17486)
                     /locus_tag="ACIZD4_001695"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HGC5990633.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILSEARQLFDV
                     VIFDMPPVVAVTDAQIMSLKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(17498..18277)
                     /locus_tag="ACIZD4_001696"
     CDS             complement(17498..18277)
                     /locus_tag="ACIZD4_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HGC5990634.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(18293..19237)
                     /locus_tag="ACIZD4_001697"
     CDS             complement(18293..19237)
                     /locus_tag="ACIZD4_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC5990635.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(19283..20062)
                     /locus_tag="ACIZD4_001698"
     CDS             complement(19283..20062)
                     /locus_tag="ACIZD4_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990636.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQYHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            complement(20442..22517)
                     /gene="glyS"
                     /locus_tag="ACIZD4_001699"
     CDS             complement(20442..22517)
                     /gene="glyS"
                     /locus_tag="ACIZD4_001699"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGC5990637.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLAGVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLEDVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(22519..23436)
                     /gene="glyQ"
                     /locus_tag="ACIZD4_001700"
     CDS             complement(22519..23436)
                     /gene="glyQ"
                     /locus_tag="ACIZD4_001700"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGC5990638.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(23822..24640)
                     /gene="recO"
                     /locus_tag="ACIZD4_001701"
     CDS             complement(23822..24640)
                     /gene="recO"
                     /locus_tag="ACIZD4_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGC5990639.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKEIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFINQMKSWAHVLKTSEKDMSEKEKETPEKEE"
     gene            complement(24783..25682)
                     /gene="era"
                     /locus_tag="ACIZD4_001702"
     CDS             complement(24783..25682)
                     /gene="era"
                     /locus_tag="ACIZD4_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGC5990640.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(25697..26092)
                     /locus_tag="ACIZD4_001703"
     CDS             complement(25697..26092)
                     /locus_tag="ACIZD4_001703"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HGC5990641.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFTVIVGLILFVPKIYHLLFN"
     gene            complement(26076..26552)
                     /gene="ybeY"
                     /locus_tag="ACIZD4_001704"
     CDS             complement(26076..26552)
                     /gene="ybeY"
                     /locus_tag="ACIZD4_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGC5990642.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(26581..28773)
                     /locus_tag="ACIZD4_001705"
     CDS             complement(26581..28773)
                     /locus_tag="ACIZD4_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HGC5990643.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKAIDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNGKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(28797..29768)
                     /locus_tag="ACIZD4_001706"
     CDS             complement(28797..29768)
                     /locus_tag="ACIZD4_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGC5990644.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            30473..31852
                     /gene="brnQ"
                     /locus_tag="ACIZD4_001707"
     CDS             30473..31852
                     /gene="brnQ"
                     /locus_tag="ACIZD4_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGC5990645.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
BASE COUNT         9628 a         6556 c         4782 g        11116 t
ORIGIN      
        1 aattctaacg ggattctgcg tcgtaatgga ctgccgaaat caatagattt tagagaagtg
       61 aatcagacat ttatttccag tgtcagcaat caacgcaatc atattccaag aaaatcattg
      121 aattacagaa caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc
      181 ttaatttgac aaatcatata atttaaaatt aacattgatt ctcctatgaa aatatctttt
      241 acctttctcc tgtgaaaagg aaatttcctt ttttatagtg ttattgatat aatcagaata
      301 ttcatcaaac tctgtatctg gagttaaaaa tctacagtaa catctataag ctttgctagt
      361 aatcttcttg ggttctctct ccattgtcaa gcaacatcaa aacacctact tactattcga
      421 ttcttttctg ccaaaaacga gtcagcatca ctcacaactt atgtgttgct gactccgact
      481 agtcctttgt tcaatatcaa cttattaaac agatataata tttttcttta tttcgtatac
      541 tccaagactt ccatctttct ttcatcttat ctctgaaaaa aacacagcaa agtgccctta
      601 ataaatatac attagaattt gcaaattttt tcatcttaag atatatccta ttcatattct
      661 ttacaatcct aatgggtgat tacaaatcta tttagttcaa gttctacatt ataaacacct
      721 ttcttgatag tatcatctgc tgcacaagcg atgtcgatcc acttattagg ggatttacgt
      781 gctcaaaagt ggctattcct tttgggaagt ccatccataa taatggtcca tggatttttt
      841 tagggtcttg tcgttcaaat ttctcaaaaa ctttattata cttccatagt tttataatta
      901 tttggtttca ctttggctcg ttcaaacacc aacttgtatt tcttttcaac gttcgaactg
      961 gagccccccc tataatctca ttattatttt catgactttt tactaccgtg gaattacaag
     1021 caacaacaat attatctgct aaatgaacac ctttctatat cacgcttttt gctccaatcc
     1081 aacaatgttt acctataact attttattat ttttattcaa aatcctatga gtattcaatt
     1141 caaaaatcgt atgtgaatcg gtatccataa ataatgtatc ccacgatact gtacagccat
     1201 ctttgaattg aatttcctta aagcaaatta tactcatttt tcctgtcgaa ttaaactttg
     1261 acccaatatc taaaactgca tttttcctta tgtcaatatg agccccttgt gcgataaacg
     1321 ctggcccttg tattcttagt attccttcaa tacttataat cgtttcttca tttcccgcag
     1381 tatttaatac tggaaagccc aaataaacta tttttccaga ttgtaatact atctcaattt
     1441 tccctctcga tttgcgtgta atccgtactt tacgatgcac caaaataggt aatctccacg
     1501 catctgaaat atgaagaaat ttataattga agtatatcgt tttaggtaaa tttaatatat
     1561 tctttattat caatccgagt ctcatctttc accatctctt tttgtaatca aaattagttt
     1621 ataaaggatt acacccaata taccgcccaa cgtattatat acaaaatccg aaatttgaaa
     1681 cgttcctagc ctcaaaaaaa gttgtaaaaa ttcaattatt gctgaaaaat aaaatgcaat
     1741 ttttcctcca tatactattg aggaccatat tttgggtttc tttatatttt catatttaat
     1801 agacattacc atataaacat atggaataaa aagaataata ttttctaaac acgctgtaga
     1861 taactctttt gttccagttg ttgtattata cttataaatc caccagtctc ccataacatc
     1921 agataaagga tttaaccaaa ttgttcgatt gattaatgtt gtaaataaaa tcatcgcagt
     1981 atagaatatc aaagcacaaa cttttctata ttttctatcc ttctttaaat gaagataaag
     2041 ttccattagt atacgtttat agccctcacc tgcagcaatg ccatctgttg catacataaa
     2101 atagaccagt cctaaaattg tcaataaaac agcaaaccca aagggttcat ataatttata
     2161 taatatatct gtaataattt ctgcaatcac tattatcata attatttctc caatatcaag
     2221 tatacactta tcgcttccaa ttacacatga tcatattaga gtgtattatc acattctcta
     2281 atattcaatt tatttttcct aaaatattcg aaataatcgt cttgataacg agtaagtatt
     2341 tttatacgat tgataacata gtaacaatat ttttaattat agtaaaaaat catctgcctt
     2401 tttcatccac ctaatcttat ttttcatttt attcaacatc cttaaataaa cttccgttcc
     2461 taagctctat aatatcttct taaaaaataa tattatggtg tcgttttcaa actcgtaatc
     2521 ttttacattg gaaaaataca tacttttctc aatgtagcaa ctcctatctc acagtattca
     2581 aaaattcttc aatattatga aatacttgtg catgttcttt aaataccttg tcagtctgtt
     2641 tataatcccc tactaaattt tgcattgctc ccaactcttc gacaaattgt catctccatc
     2701 tgtaaacagc cctaaaaact catataatgc tttttcatca atatttttcc catattattc
     2761 tcggtatagt ttcacaagtt ttacggattc ttcatattgt ttatcttttt ataatattca
     2821 tctagggaca taattacttt tgctagattt cctgcaacaa cacaatcgtc tgatacgtcc
     2881 ttgtttacta aactatttgc acctataact acattatttc ctatatgtac accctttagt
     2941 attctagact tcattcctat aaaaacatta ttacctattt tgatcctctc cgatgatccc
     3001 aaagcttctc catactactt ttaaaaccga tcaatcataa acatgagtca aaattgtaac
     3061 tccttcatat catctccaat ttcaacaaga gtcttcgttg gaacaaaaac tatacatcgt
     3121 tcgcctattc ggcagcctaa aaattgtagt tactttatat atcattctga tgtctcttct
     3181 catcttttta ccaataccga cgtaagaact ttcaaaatat acttaaactt cttattacgg
     3241 atattaaaca gaagaataac taaaatcgat atgacaaccg atataactaa atttatcact
     3301 aaacttatca ctttgaaatt tccgatatta acatacgaac aagcaaaata acttaaataa
     3361 gaagcaacaa aagctattac acacaaactt atgagcttcc aaacatattt acctgccgat
     3421 tcaaatttaa atatattttg gaaaacatta tataataacc agggtaaatc aaccaacaat
     3481 actgaaacaa tggttgccgc caaaactcca tataatccga accaattaac gaggatgata
     3541 tttaatacaa tgtttatcat tgctgtaatt aatggtctaa acctgtctgc gtaccatatt
     3601 ccagcagcat ctttgtataa cccaattaac tgatcaattt catataagaa aaaatgaact
     3661 atcataaata taacaaatga aatactcata agattatcac ttcccaccca gataatcatg
     3721 aacggctgaa ataatgtaat aaagcatgca caactaattg ccagaaacca acctataatt
     3781 gttgtaatat cacaaaaatc tatataattt ttttcttgac tttctacaat aagactgtta
     3841 cctatacctg ctatacatga ttcataaatt attgcaaata tactcattat ggcagaaata
     3901 ataaagtaat aattctgata aatcgcaagt actgaaagac ctaagaaaga tgaaataata
     3961 attgaatctg aagatcgtaa tattgtaccg cctaccttgt ttgtaactaa tccttttact
     4021 ttttttataa tatcgtcaat agtttctttc tctaactcac caacaggagt ataatcagga
     4081 tacatctttt gagaaacaac agcacacatt aagttaagaa ctatttgtcc caaaatagaa
     4141 gccaataaat acaaatagta attttttaag aaaatcagaa catatgcctg cattacaaat
     4201 tggaatgtaa aagtaattag catagacacg ttaattacat catttctttg atgtgcatat
     4261 attagactct ttctatatga aaataaccaa tacgacaaaa cagtatttat caaatacatt
     4321 aaatacaaaa ctgtcatatt taaatttcca ggaatcgaac ctttaactaa aaatctcaaa
     4381 aaaggaatgc ataacaatcc taatgtaaac actatccatc caataattga aaagtacttt
     4441 ttatatgcgt tcagtaaagc acaaatctct tttctattgt cttctgctat aggtttatac
     4501 atacttacag ttagtgcagc acctattccc aattccgcta aatttaacat ttgaaatata
     4561 gatgtgaaca ggttgttcaa tccagcatac tccattccca tctgataaat cataagtgta
     4621 cgcataaaaa agggaatgat aatctgatat aacttaaaaa ttgttccagt aattatattc
     4681 cttttagcat tttgtttacg attaattatc atatcatatg gctccaaact ttctattttt
     4741 tattgttacc taatactata taatttctaa aatcttgaaa tgtaataggt ttcttctagc
     4801 tctttgatta attacgctaa ttttcatgtt tggacaacca caaaaaacta tacattttca
     4861 atcaaagcaa cccattgttt tgtaatttct ttcaaattaa atttttgtac attattatat
     4921 gcgttcagtg acattctcat tgctaaatca gtattcttag taaacattat catgctctta
     4981 gctaattggt ctatattctt atcttcaacc aacatcccat taaaattatg atgtaccaaa
     5041 tctctcggac cagttttaca atcataagaa ataactggta atccataaga ctgtgcttct
     5101 aatataacca taggaaatcc ttcataaaca gaactaagca cataacaaga tgcagattta
     5161 taatattcct ccacatggtc tgaatgccct gctatagtta ctctttgcag atttaaatct
     5221 tttatctgct ggcgaagatc tttttctaat tcaccttttc ctacaatgat aagatcccaa
     5281 tcatctactt ttttttctac aattttccaa gcacttatca tgtcagcaaa atttttctct
     5341 tccactaatc gccctactgc aagaaatctc tttttatcat aatgatattc gtactcgata
     5401 ttagatatac acggatttgg catagttata acaaaatctt ctgataaact atattcatca
     5461 atatgttttt gacgatcttc ttctgtgaga accacaagcc tctttgcata tttttttatc
     5521 aattttttag ccttgaatct cttcttttct ttcagcattt ccattgtcca gtaattaaaa
     5581 tgttcccaag aaatcaattt gcactttgtt cctttaattg cccttgtagt atacaaagac
     5641 aacaaagtat caatatcaat tactatatca aattcatttt tgcatatata cttgtgcaat
     5701 ttccaaaccg gatataaata agttctatat aattttccct ccgttttagg atttaacata
     5761 taatcaacct taatcgtctt atctaaccca aaataaggct ctccactatt ccaaaagctt
     5821 aaaatagtga catcataacc taaatcagac aagctattgg caataatact ccctactctt
     5881 tcagttcccc cagaacgaga aattacacca ctaatgaaac aaattttctt caaagtactt
     5941 ttctccttta taagtgtaaa aattttttca gtgcaagtaa cctgttaaat tttttttgtc
     6001 caattgttga ttttaatcta taaacaaatt tttgtttagg tgttttccaa gatgcattat
     6061 attgatgaat gcttattgta ttactagttt tataaatttt tccagtatca taatccttgg
     6121 cagcaaaata atccgtagga tagatatgca ggccatttat tatttgttcg ctgttatcgc
     6181 gaaccaatcc aatagattca agataatctg taatataata cggactcggt ttcaagttca
     6241 atgtaccatc attttgataa aaacttaatg aatcgtaaat atcccttaaa cctttaataa
     6301 cagaatgtcc ttcttctgca ccaaaaccaa taccgccatt aacccagatt tccccttcaa
     6361 atcccatata ggcatgattt tcacgaagta tatctaacga cttaattagc tcaacatctg
     6421 tatctaaata aaatccacca tgattataaa taatatcaaa tcttgcataa tctggaacaa
     6481 aaccccattt acgttcttta tatgcatcgg ccatataacg gttcttattt aaatcataat
     6541 ttgattcatt ccattcaata atctcataat cagggcaata ctttttccag ctttctatgc
     6601 actttctatc ttttttcgga agtggatttc ccccgaacca acagtaatgt atcttcttag
     6661 gaatcataat atctctcctt ttgtattttt ttcactataa taatgctctt tccttttcac
     6721 aacttcaggc atggctaaaa tcatataaat cagtggcccc gttgtttcac ccctaagtgt
     6781 tgtgttatac acaaaaaaga ataccgacat aattgcaata actttaacaa gacttgcatc
     6841 tttatccttc ataaaagatc tttttgcatt gaaaaatgtc tttattataa aaaataggaa
     6901 tatcgaaact cctaatattc caacttctat aaataaccaa atatgatgaa aatactgata
     6961 atgaagatta ccaaacgatt tataaaactc actgacaaaa aaattggtaa actctgcatt
     7021 gccaatgcct actcccatta ggactaatct aaaattatta ttaaatattt catctactac
     7081 tctagagata ccagttattc gatttaaatc accaacacca tcatatccag aatctcttga
     7141 cgcatattct aaaagacctt gaattgtgaa attatcagca tagctttgtc cattatcgtt
     7201 caatgtaata aatattgtta taaaaaagga taatactatc gacacaagta ttacgcatga
     7261 taatatcttg atcactactt taaaatcaac ttttaaagtg aatactattg caacaaatat
     7321 tataaataat tcaggaataa aaactttcaa ttcagctaat gcagacataa aaagtgctgc
     7381 acaaacacat aaaataaaat ggatgaaatt tttttctccc ttgaaatatc cgattgtaac
     7441 aacagtaact gtcacacaca aaattaaatt caatggcata ttacaacctg aataattcca
     7501 aaaaactcca cctatcatat ctcctacaat tgttccagtt ggataggtga ccatgaatct
     7561 ttcaattaaa caaagtggca gtgaaatcca gaataatttt tcaattatag cgaatacttt
     7621 atagtaatct ttaattgtta aatatgttgc acaatttata tatactatga acatacgagt
     7681 gttatttcgt atcccccaga taatcaatcc tatattttct aaattaataa ctgagctaca
     7741 aatagaaact agtaaaaaca aaactatcag catctcattt ttgctagcat atattccttt
     7801 tctgcgtcta aagctaagtg catttaataa cacaaagata ttaattatat ctcccaaata
     7861 taaaattgct cttggggcgt taaaagtata tacaagaact atggagattg caaaaaatgc
     7921 caacgtgaac aatgtccaat ctgctcctga ccatcttttt attgaaatac gcatcgttat
     7981 tcaccttctt tcgctaaaaa ttattctaaa aatacttttg ttaaattaac ataccctatt
     8041 atttttgccg gtacacctgc aagaattgca ccattctcta gacaatcttt gataacaata
     8101 gctcctgccg caacaactac attgttagct atttttacat taccaataat ctttgcaccc
     8161 acgcatacac gtacattatt tccaattaca ggacacttag gatcgattcc atcatttcca
     8221 atacagttat tcccatataa gtaacaattt tttcctatta tggcgttacc attaataaca
     8281 attccttgtg tatggtaaaa tcttacacct tcatcaaata cattttcacc acactctata
     8341 ccacattttc ttcccaaact attcattctt ctgcaagaca caatatacat aatcgcataa
     8401 atgatatttt tctttctctt tgaataataa taagatgtaa ttctcattcg acgagtatac
     8461 cgccaagcgt tgtagtccgg atgtgatttc attattttta gtaattttgt gtgttgtcct
     8521 ttagattcta tatatagatt cttttccata cgaagaaccg cttttaaata ttctttactg
     8581 ctaatttcca ttcatatctc ctattaattc aatttatact taacaatttt attcggattt
     8641 cttgcaacaa gagcatcatt caatgctact gaatctacaa cgatggatat gttatcttca
     8701 tcgttgattc caccggatac aatattactt ataaaaatcg taacattttt tccaaaagaa
     8761 gggatgtccg tgatgtataa tgcccatttt ccgatatttc cagttattta aacctaacga
     8821 atttttacaa tagtacaagt atcacaatca ttaatatata actggaatat aaatctccaa
     8881 aaattcacta tagtacagtt ttttatgatt aaaatctcct atttctaccc attccgctta
     8941 aatatgctaa tgttttaacc ccaataatgg attggtttag taaaaaatag ttaaatattc
     9001 gttgtttaat tggattttgt ttatatgggt atgagtgaat acaggcaatc aactcatcgt
     9061 tcataagtat cttagacaaa taggagttta aatcaaattc tttattaaaa ctagcatatc
     9121 taactgcctt ttgaatacaa gtacgacagc gtcccaacaa aagtctcctt gttttgttta
     9181 caaatatctc attttctaat atatagctta aatcgccttc aattttttta actaattcaa
     9241 tattacaatc gaactcatta tctctaaaat tatgtgtcaa tgaattatta ttattacatc
     9301 tataataata gatacaatct ttaataaaac ttgttatttt tgaatgttgc aaatatgaaa
     9361 tatggaatat gatatcttca gatatataat ccctttctga cggaaacttg atattgtgct
     9421 gttgaattat ctcagatgaa tacagcgcat gccaaactga cattggcaat ataaaatcga
     9481 ctttataact cggctcagtg ccaatcattc caagcaacac tttttcaatt atagcgttat
     9541 ttgtaaatat cgtactatca tatcttgctg gctttgaaat aatattatta tcatcataat
     9601 attcataata tccagcataa catgtgtctg cattactcct ttttatacca tttaacattg
     9661 cttcaatata attagctgca acaaaatcat cagaatcaat aaaagcaaca tattttcctt
     9721 ttacatgttc aagtcctgta tttcttgcca atcccaagcc agcattattt ttatgaataa
     9781 tacgaatcct tgaatccttt aatgcatagt cttcacatat tttattagat gaatccttag
     9841 atccatcatc cacaattata atatctaggt tcttatatgt ttgattacac actgattcca
     9901 aacaacttcc tacatacttt tcaacattat atacaggtat gattacacta attagatcac
     9961 tcgaattcat ccttctatcc tttcactcac gttttctcaa ttagtcaatg acggcatcaa
    10021 cgattttctt aaattctctg aaaaaaatag actctgatct tgatgatgtg aatgacatac
    10081 tatcttcttc tagaaaaatt atttccttta aattatttat taaatcaata atatgatcct
    10141 cgtaagtatg ctttcccttg gaataatgaa aatatacttt tgtattacac aatattgcaa
    10201 ttttatttct taatatgatt atttcactca ttcattactg ccacatatac acaacttata
    10261 accaccccct gcaaagttta gggtaagtta tcagataata tcttcctctt catcatccag
    10321 aatacaaaat ctatttattt atagaaatat cattaatgtt tttatataat gtaccgtgct
    10381 tgtactcttg ctctattaca agcactaaaa cactactatt catttgaatt cttacacgga
    10441 taaaaattta catcgtctat ttcaatattt tttctctcta ttttattcac ttaataagtt
    10501 cattacataa tcgaaacatt ttttattttc cttgtcatca ctccttgctc cctttttgat
    10561 acagatttaa aattctatca aagaaatttc catcgttaaa tttcgttatt gccaaatcct
    10621 tcgaacaacg tgaaaatttt acgtatttat ctttatcatt gatttttagt attgcagatg
    10681 tcaacgctga tacgtcacca ggttgaaaca aatatccatt ttctccatca cgtactgctg
    10741 aagaaatatc tcctacatct gtagcaatta caggcattcc ataagaaatc gcctctagaa
    10801 tagatatagg caatccctcg ttataggacg gtaaaatcat cacatttgat cttctatagc
    10861 actcctcctt tttttctccc acaacccaac ctgtaaattc aaaatacgat tgcaaattat
    10921 attcttctat caattctttg agcgatattt cttcatcacc tgctccagca atctcaaaaa
    10981 taaacttttt ttctggatat tgttctgcaa tgtttttaac tgcttctacc aaatcgtgta
    11041 caccttttcg ctttatcaaa actcccataa acagaaatcg gcacattttt gaattccact
    11101 ttatggtata ttctggaact acaatagaat tttctacaac aacagtttta caatttggct
    11161 caatttcttt aattatcttc ttccattttt ctccaagtac aatcgtggaa tcagactctc
    11221 ttaacagcaa gcgaatctga ttttgttttt ttacagaaac actatcatac cattttttaa
    11281 attccgatcc atgaagatgg atgattacag gaatatttaa taatctaaac cacttattca
    11341 gcacatattt cctactaaaa ctccctctgt acgacatgtg catatgaata atattaggtt
    11401 tactcaataa agagatacct ataattttag caaatgcata cataaaatat aaagatttaa
    11461 atattgcatt tccaccctta taactcggta taaaagtcat ctcgatattc tttttttccc
    11521 aattaaaatt gagcatttgt gtaattatac ttgtaattcc accttttacc gagctgtcat
    11581 taccaatcat aagtactctt tgcataacgc tttactcctt atatttatat tttttctatt
    11641 aatacctcta tcgaattaat aatcgtttcc gtgttagata catacttgtt aaacatccga
    11701 actcttgttt ctttaacggc atcttctaaa ttttctaatt cataacaagg atagataata
    11761 ttcatctcat caaattgtct aattaactgc agttggtgat catcgacatg ctcaccatac
    11821 ttagccaatc gaggaacagc aatgaccctt ttaccttttt ttacggcccc aattatagca
    11881 cctgtacctc catgagtaat caccatttct gctttttgca tagtttcagt aaactcatcc
    11941 ctatttagaa atgctttata ggaataattt agtggtttat aatcactata accactctgt
    12001 gcaaatgtac tttcgattat tactcctttt tcaattaaat catcaatagc ttttaacaat
    12061 ctatcaaatt gaaatttttg tgaacctaat gttataaata tcattttttt ctcctattat
    12121 ttaatatatc ccacccaaat aaatagcatt aggataaaat tgtagcatag tttcccactg
    12181 aacataaaat tgatctgcaa aatgatacat caattttcct gtctgagtag ggctggttac
    12241 ttttgcaaac gattcaatat aaatcagttt ttttcccatc atttttgtta ttaagcagat
    12301 agggatcata gctaaaacac ctgtacaaat cacgagatcc ggtttttcct ttatatatat
    12361 aataattgat ttgaataaat taataagtat agtacacaaa aaaaactttt cttttctatt
    12421 tacttgtctc atgtagtacg ttttttcgcc ttttgactca gctgaatatt ctgtctgttc
    12481 tgttataaca aaactctcat acttctccat cagtggtttt aacatcatta actgttcata
    12541 atgcccccca gaggaagccg caaaacatat ctttttgttc atattaacct ctctatcagt
    12601 cacgctgaaa aatatctcta gtgtaaactt tttctttaat atcatccaag caggtatcat
    12661 atcgattggc aataatagaa tcacacatcg ccttaaactg ctctaaatcg ttgataacct
    12721 tacttccgaa aaaagtctct ccatctttca gtgcaggctc ataaatcacc acagtcgcac
    12781 ctttagcttt tacgcgcttc ataactccct ggattgaact ctgacgaaaa ttatcactgt
    12841 tgctcttcat ggtcagccgg tatataccga ttaaaactgg attttccctg ttgacatcat
    12901 actgattata ttcagcgtag ttgtaatagc ccgccatctg aagaacacga tctgcgatga
    12961 aatccttacg ggtacgatta gattcaacga tagcctcaat caaatttcca ggaacatctg
    13021 catagtttgc caacaactgc ttggtatctt ttggcaagca ataacctcca tatccaaagg
    13081 atggattgtt gtagtgagtt ccaatacgag gatcgagaca aacaccattg attatctgct
    13141 gagtattcag ccccttcatt tcagcataag tgtctaattc attgaaatag ctgactcgca
    13201 gtgctaaata ggtatttgca aacagcttta ctgcttcggc ttcagtgaat cccataaaaa
    13261 gagtatccac gttctcctta attgcacttt tctgcagaag tgttgcaaaa acatgagcag
    13321 catttaacaa gcgctcatca gtcatatcag taccaacaat aatacgagat ggatacagat
    13381 tatcatataa agccttgctc tcgcgcagaa actctggact aaaaataatg ttcttactcc
    13441 ccgttgtctc acggactgat tcagtgtagc caacaggaat tgtagacttg atgaccatga
    13501 tggtatcagg attcacgtcc atcacaacct caataactga ctcaacagca gaagtatcga
    13561 aatgctgagt acgactgtca tagttagtcg gtgtagcaat aacaacgaaa tctgcggatt
    13621 tataagcgct ccttgcatcc aaagtagcag ttaagtcaag ttctttttct gtaagatact
    13681 tttcaatata ttcatcctga attggagact tccgtttatt aatcagttca atcttttcag
    13741 ggataatgtc taccgcggtt acctggtgat gctgcgccaa tagtgtggcg atactcaaac
    13801 caacataacc ggtgccggct actgcgatgt tgtacttttt cttcacaata tctcctcttt
    13861 cctctcttaa gtatggagaa tgttactcct acggctattc atcatgtcaa aataacacag
    13921 cttagaatgt tgataaaata attttccaga atgtgataaa atctctttca tttataaacc
    13981 acacatctaa ttttatctat tctccacaag acatgtagag tattctttaa taacaagata
    14041 cgaccttact aaatacttca aaaaattatc atatttaatt cataaatata aatcttcatt
    14101 ttaaatgtat gcccaaaaat ttatctgtaa tgcgtcatca aaatctagat tccaaatctt
    14161 tatcaatttt tatccactca ttctaccact ttagtaatat tttctattta taacactttc
    14221 gtcctacatt gatccccccc tctgaagtac agtttttact gtcttaaata aaattttaaa
    14281 atctaacccc atactccaat tttttatata ttccgtgtca agttttgcta cttcttcaaa
    14341 atcagtaata tcacttctac cacttacctg ccacattcca gtaattcctg gcttaatagc
    14401 aattcttgca cgatgatgat aatcatattc ttcatactct gatttaaggc atggtcgaaa
    14461 tcctataagg ctcatctttc ctgttagaac gttgaaaaat tgagggaatt catctaaaga
    14521 cgtggatcta ataaattgac cgattcctgt cttttttgtt ccatctggaa gtattttatt
    14581 tccgataatt cttggatcaa actccatctt aaacataaga ttattgctca tcttattttc
    14641 tttcattaat tctacttttc tttcttctgc atccatatac atacttctaa acttatacat
    14701 cttgaacggt ttaccattct gacctatacg ttcttgtgca aagaaaattg ggcctggtga
    14761 attaatataa ataagtggag caataaagat aaaaataatt cccgttgcaa tacatccaac
    14821 aatacctgca agaatatcaa ttgttcgttt tataaatgcc tgttgagttg tcataacatt
    14881 gatacttgtt gtaagtactg tatattctcc tatacgacca atagattgtt ttcccaaagc
    14941 actatctgat acttttgcaa gattcaaatg tacagtaagg cccatttcag agcatcgttc
    15001 aataaattct ttcatacacg aagtactttt attcaaaata ataaagactt catctaccca
    15061 tccctgacat aagtaatccg ctgcattttt ggaatcagaa acaactgtca ctccctcaac
    15121 atcttcacca atcatgcttt tatctatgat aatgacacca tttattttat acattttata
    15181 gttatgctct ttcacattac gaataactac ttcagcaata ctactagatg taactataat
    15241 aagtgatttg ttcccctcat ttttcatttt atgtttcaag taatgtttcc ataagaggcg
    15301 agttatatat gtaattacaa cgtataaacc tcccatcaag aaaagaacga ctctagaata
    15361 atcatttcca ccctgaacac taatgagata caaacttcct aacagcacca acataatcgc
    15421 ttgctttaca gaagaagcaa attctatata gtaccctctt tttaatacac ctctatatgc
    15481 ttcaaacatg aaaataacta aaagatctgc cagttcaatg aagactgcca tgttttgata
    15541 cattggaatc acataaggat tccaatctac ctggcgtaag acatacgata gataaaaagc
    15601 aagctggata cacaataaat ctaaaataat aaaatcaata tgtttaaccc atccccttga
    15661 acttttcttg tacattcctt tttactcccc tctttttaat aaaataaatt gtattacttg
    15721 ttttctctcc taaatatctt tctgaaggat tattgactcg acaaattggc ttgtggatat
    15781 tcttatatat agaacatccg taagccaact taaaactcct taacaaaatt tttttactca
    15841 tattgtagat caaaacaagt atccaagaaa tcatatttta tttctttttt ctgcttactc
    15901 aacaacagct aaaagaaaaa tcatcataaa caaattcaac taagccaacg atccccttgt
    15961 gaaatcaagt tttttcttga tttacgaata aagagctaaa ataaaccaaa cttcttcttt
    16021 tttacctctt catagactgg ataactgatt tcatccccgt tgatcagatc ctttgcgact
    16081 tgtttcatct gtactacttt ttccttacca aagtcctttg caatctgctc atagcactct
    16141 tttaagtaaa aggtgcgctt agagacccca tgggcatcag aagcagccat ctgcacgaga
    16201 ttatgtttga ccatcgtttt ggctgttttc tggatgtctt tgccaaatac cccaacataa
    16261 cttggcgcag tgagttgggc caaacatccc atatctagga acggaagcaa atgatttggg
    16321 tcttcgcgaa aatgcacgtt gcgttctgga tggacgatta ctggtgtctt tcctagttct
    16381 aacaactcaa aaaaaagccg ttctgcatat aacggcactt ccagtgtcgg aaattcgatc
    16441 agaagatatg tatcatctaa atctgtaaat aatatttcat ctcggtggat gtcttcgatg
    16501 agcgttccgg taatacgtac ttcttgtcct tccaataacg tcaaaggcaa ctgtcttttc
    16561 tctaattcgg cttgtaacga agcgactaga gaaatgactt gtgatttttc attgctgtat
    16621 tttccattat tgtggtgtgg tgtgcataaa atatgcgtga tgccttgctg aatcgctttt
    16681 tcagccattg caatacttgc ttctaagttt tctgccccgt catcgattcc tggtaggata
    16741 tggcaatgta gatcgatcat ttctcttgtc tcctctcttc ttattcctta atttccgtag
    16801 taataaccag catctttgct atgttctgct ccgttgtaca caacacctaa gactcgtgct
    16861 tgtaccatct ccagcagttc ttttgcttta gtcaaggatt ctttacgtga catattttca
    16921 cgtacgacca ataaagtgcc atccgttttt aaagacatga tctgtgcatc tgttacggct
    16981 actactggtg gcatatcgaa tatcaccacg tcaaataact gtcttgcttc ggataggatc
    17041 tgatccattc ttggcgagct taacaattct gatgggttgg gtggcttagg tccactaggc
    17101 aaaatcgaca agttctcgac tggcgttcgt tggatcacat ctgctacact tcctgatgaa
    17161 ctaagtgctg tacttaatcc actggcattg ttcagctgga atgtcttata gacgacgggt
    17221 ttacgtaaat ctgcatcgac tagtagaact cgttgacctg atttagcaaa aacgactgca
    17281 atgtttgctg cagtggtgga tttcccttct ccaggacctg atgaagtcac gacaatcgtt
    17341 ttgatttgct gaccagctgc ggaggcaaac tggatattcg tccggatcgt acgatattgt
    17401 tcggcgattg gtgaagatgg gtttgttaat gtgatcaaac tgactgcatg agtttgtgct
    17461 gctttttgtt tctgtgttcg tgccattttt cttcctccta gactcttgag cggcttctgc
    17521 gtgatggggc tgttttatcg tttgtagctt ttggtcgtgc aggagctgtt ccttttttac
    17581 ggataccagc gttcaattct ttcgctgaca tttctggaac tgttcctaag attgggaatc
    17641 ctaatgtatc tgtcacatat ttttcatctt tcactgtccg atcgagtaat tccaataaga
    17701 atgccagacc tacacctacc atcattccta acattaagcc agtcattaaa ttcaatttat
    17761 tatttggcga aacaggtgtc gtattggcaa ctgcacctga aatgatcgag attttatcaa
    17821 cattcatcac atcttttgcg ttctcttgga aaacttgtga agttgtgtta gcgatctgtt
    17881 gagcagccac tgcattcgta cttattgcct gaatcgagaa catttgtgaa ttttctgcct
    17941 gattaactga gatggcatct ttgatttgtt cagcagtcat tttcacattg tcttctgttt
    18001 ctaaacgatc tttgacttca ttgagcacta aatcactgac gatcatatct ttatacgtat
    18061 tgatcatttg caggttcgta ttgacatcat tgacatttgc agtgtctgat tgtggcagtg
    18121 tcacgatcaa ttgtgcttgt gaactgtatt ttggtgtcaa gatgaaaaat gttacgattc
    18181 ctgagatggc caagccagca aacattgaga tgatgattat taccaagtgt ttgcgtaatg
    18241 tttcaaaaat ttctttcaag ctgattgtct cttccatttt ttctccactt tcctatttat
    18301 tctctagatt catttgatct tttaattctt ttttcacacg atcaagttct tgatcactga
    18361 ctttttgata ggagatatta tcttgcatga agccttctcc ttgcagctga tcttgcttaa
    18421 tcgtaccaaa tgcctcccga taatctaaag caattttttt catttcatca aagttcatgt
    18481 ctgttttcat attcgactct agagcattca aaacggattg atagttgctg acaccgttta
    18541 gactcaatac ttttttcgct acgccttcta cgatctttct ttggcgccct tgtctaccgt
    18601 aatcaccatt tgggtcttca taacgcatac gagaataaga taatgcctga tccccgttca
    18661 atgtaatttt accgattgga aagtcatagc catcttgtga gaaagtgagg tcattattga
    18721 cttcgatacc accaactgca tcaacgagtt cctttagtcc tttcatattg atagagacat
    18781 agtgatcgat tgggatgtct acatattttt gtacggtatc catcgccatg gcagctccgc
    18841 cgaatgcgta agcgtggttg atcttgtctt ttgtgtcacg acctacgatg tcgacatacg
    18901 tatctcgagg aatgctgacg atcgttgtct gtttgtcttc aggactgact gtggcaacca
    18961 tcatcgtatc tgatcttcct tgatcgaccc gacctaaatc tccagtatca atccccatca
    19021 atagaacaga gaaagattct tgtttgtcca gatcaactgg tttcgttcgt tctccttggg
    19081 ttcgttccac tgattcgtaa gttttctcaa tagaatgtga gagatccaga tataattttg
    19141 ctcctactcc tacaattgct aatactaata cgataagaac tgctaaaata atcaaaaata
    19201 tttttttccc tcttgatttt cttcttcgtc ttgccatagt ttcctccgtt tgctaacctt
    19261 gcttgaatca acgttttaac tgtcaatagc ttatattgct atagcccatt tgctgagcaa
    19321 cagtttgtgc ttttgttgcg tatgcggctc ttattttttc attccggatc tgctctattt
    19381 gactgagcgc cgtcaaatat tgatcgtaag tagcggtagc tgttacttga ccgtctttca
    19441 gcatcgtatc gaatagctga tctagttgcg tgacttgtgc aatttgggta tcagcgaatc
    19501 ctagatattg cataacgact gttttccaag cactatcctt aaaaaagctc atattttcac
    19561 gtacatgggc gacatctgca cttgccaact tttctttgat gatgacatca tccacagctt
    19621 gctgccagtt tgatacgttt ttagtaaata atttattgac agccgtctgg atcttcagtt
    19681 ttgattctgc atcctctaac tgcgttaaga ctgctttctt ttcttcttgg atcgcagcag
    19741 cttctttagg taattctgat tccttgatgt cataatcatc tgccgaaagt ttgatagaag
    19801 atagtttatg tgacaaattt gaaactgttt cttctgttat ttcaggattt aggaaaattt
    19861 tttcttttgt actgtacagc ttatctactt cttttgataa agaggtcacg gtgtcttttt
    19921 gattggtgat ggcagattct gcgtaattga tccgttgatg atattgccgc tgattattga
    19981 gatggtatcc aaacaagcaa atcacaatag cgcctgtgcc taccgccaca gtagccaata
    20041 acttgacgaa cggcttttcc atagattcac tcctaaatat tgatgataga taagtaaaga
    20101 tgtgattcat tcacatcaga atgagcgctt tttattttaa aagcataatt aaactaatat
    20161 attcatagaa atatttataa acaggttttc cctatataat cataccacat acagtttttt
    20221 tgactaggga aattcctaat ttaaaagtaa ataaaacagt aacaagatta taattaatcg
    20281 ttttcatttt tatttcctca cttttcatga gcgttttgaa aattcgaaca aagaataaaa
    20341 taacaaaaat tattaaaata gaattaataa cagctattta taacaaaaaa aacagagaca
    20401 cagcacgttt cgtgcatgct ctctgttttt caaacaaaag actattttgt gatgatttga
    20461 tccaagcttg ctaatgacaa agccatggca gctatttgac ttagttgtgt tagtcggttc
    20521 ttacgtactg ctggttcatc agccatgacc atcgtttgat caaaataatt ttcgatcagt
    20581 ggacgaagag cgacaagctg gtcgtagttt tcgtggatcg tttggtcagc aaaacttgct
    20641 ttcattgctt ctactgcttt gtgtaattct ttctctgcgt cgttttcgaa cagctcaggg
    20701 tctacttctg attgtttttc aagctgcgct tttttcgcta agttcacgac acgtgtcaaa
    20761 gcttccattg aaggtttgaa gtcttcatct gcaagatgtt gtttgaacaa ttgtgctgct
    20821 gcaaatactt ttgtcagatc tttttgttcc gcattcaaaa cagcatcgat gacatcatga
    20881 cgaatattct tcgttgtcaa taattggcgc agacggcctt tgataaagtc gatcacttgt
    20941 tgttgccctt ctgataaacc aatgccgaaa cgatccgtat ctttactgat aacatcgcta
    21001 atcgtttctt gcagaacaga caaaggaaag gcccattttt tcgattcgat gatccgaacg
    21061 acaccgtatg cttggcgacg taaggcataa ggatcgtttg acccgcttgg aatcatccca
    21121 actgcaaaga aagaaaagat gctatctaat ttatctgcaa tcgctaaaac agaacctact
    21181 gtagactgag gtagctctcc ttcactggat ataggcatgt aatgctcacg aatcgctgtc
    21241 gctacagcag gtttctcgcc tttcagaaga gcatattttt cgcccatgat cccttgtagt
    21301 tcaggaaatt cccctaccat gttggttact agatcaaatt tatagatttc agcagctcgt
    21361 tgcaaatcca tcaattcttc ctcagatagt cctacttgtt cgccaatgat acgggcaatg
    21421 acttgtaccc gttgcatttt ctcatagata ctaccgattt tttcatggaa agtaacagtt
    21481 tttagttttt caacgtattg gtcgattgaa gctttcttgt cttcattata aaagaattcc
    21541 gcatcttcta aacgagccgt caatactttt tgattgcctc gaaccacatc ttccaatttt
    21601 acccgatcac cattacgagc agaaataaaa tgaggaagca gcataccttg atcattccgt
    21661 acctcgaaat aacgttgatg ttctttcata gaagtgacta gtacttcttc aggaacagaa
    21721 agatattttt cttcgaagtc gccagaaaag acagttggat attcgactaa attgttgact
    21781 tcttctagta aatcttcgtc tagatcaata acccagtgat ttttttctgc taattcgttt
    21841 gcttgtgtaa cgatcatttc ttgtcttttt tgcggagacg caatgacgaa ttgttcattc
    21901 aatttttctt catattcttt tgcatgcgca aatgtcacat cttcgcctaa gaaacgatga
    21961 cctcgagagg ctctgcctgt tttgacatcc aagatttcga atgggattac ttcgtcatct
    22021 aacaatgcca cgatccagtg aatagggcgg atatattcaa aatcgtattc tgcccaatgc
    22081 atcgttacag ggaaagtcaa acttttgatc acccctgcta agcctgtcaa tacttctttt
    22141 gcttccttac catgagtgta tttcgttaca tagacatatt ccacaccttt taattctcta
    22201 aaagtgatag cgtctgtcgt cagaccttgt ccgcggacaa atccttccgc tgctttcgtc
    22261 cagtttccat ctgcgtccaa agcaattttt ttggctggtc ctttgacttc ttcttcactg
    22321 tccgcttgtc gttctggaat atttgttact ttgattgcta aacggcgcgg tgtggaaaat
    22381 gtttcgatcg tatcataagt caattggttt tcatctaaaa attttgctgt tttttcttct
    22441 aattgtttca tgcttggtgt gacaacatgg gcaggcattt cttccagccc gatttcaagt
    22501 aataagtctt ttgccatctt attcagcctc cttcacggtt tctggatttg ctgtgttttt
    22561 attcaacaaa gggaatccta atttttcgcg ttctgccaca aagattttgg ctacagcacg
    22621 agccatgttg cggatgcgag aaagataacc ggcacgctct gttacggata ctgcaccgcg
    22681 ggcgtctaat aagttgaatg tatggctaca tttcaagata taatcatacg ccggatgaac
    22741 aagattttca tcgatacagc gtttagcttc tttttcaaaa cgatcaaagt tgcttagtag
    22801 caagtcttgg tcgcttactt caaaagaata tttggaatgt tcatattctg gttgtttgaa
    22861 gatctcgcca tatttcacgc catcagccca ttctaaatca tagacacttt caacttcttg
    22921 gatataagaa gcaagacgtt ctaatccata agtgatctca gaagttactg gtttacaagg
    22981 cagtccacca acttgctgga agtacgtgaa ttgtgtgatt tccattccgt caagccatac
    23041 ttcccaaccc acaccggcac agcccatgga tgggttctcc cagttgtctt caacaaaacg
    23101 gatgtcgtgt tctaatggat cgattcctaa aaggcgcaag ctttctaaat aaagctcttg
    23161 aatattctca ggtgaaggtt tcatcaccac ttggaattga tgatgctgat acaaacggtt
    23221 tgggttttca ccataacgtc catcagctgg tcggcgagat ggctctacgt aagcagcatt
    23281 ccatggttct ggtccgattg cccgtaaaaa ggtatatggg ctcatcgtac ctgctccttt
    23341 ttctgtgtca taagcttgca tcagcatgca gccgtttgat gaccaaaatt tttgtaatgt
    23401 taaaatcata tcttggacgg tcaatttttt actcatctgt tttgcccctt tcaattttaa
    23461 agcgttgctg tcaaataaga atacaggaaa gaaaacgaca aaaaatccct atgtctgatt
    23521 acagacatag ggacgaataa ttcgcggttc caccctactt ccgaataaag attcggcagc
    23581 ttcatttatc gtactcgcaa gtgcctcttc aaaaatcgtt tgggtccggc tcccactctc
    23641 ccgaactcgc taaaccacgt gttttttact gatcttggtc aatgtacgta ttcattttgc
    23701 agttttcttg tttctataat agatcctatc actgaacgat ctatttaatc tatggttaat
    23761 aatagacgga actccctgtg tttgtcaaat ggttttgatt ttttgttgta tgttttattt
    23821 actattcttc tttttcaggt gtctcttttt ctttttcaga catgtctttc tctgacgtct
    23881 ttaatacgtg tgcccaagac ttcatttgat tgatgaactt tttgcttttc aaatggatac
    23941 cgacatattc atcatacagc tggtcgatga gttcacggat tgcttgtttg gtttcttctt
    24001 tcagatggat tccactaatt ttatcataag aaatagctga aaacatccga acgaaataaa
    24061 cagctcgagg atctgcatga taacggtgat cgtccatcga ccaatgtctt tcgcatatca
    24121 caccaccata tttggaagaa tagtcaaatt ttccttttgt ttccccgcat acgacgcagt
    24181 gtgtccagat tggtgcaatt ccgaagcgtt gcagtatttg gacttcaaaa atattcgtga
    24241 tgatttctgc atcgtctcct tggtccatcc gttgcagtgc ttgttgcgta aactggaaca
    24301 aatgcgggtc gtactgatga tcttcgattg ccgcatctac tagattcaat aaatatgtgc
    24361 catagccgct caaaaagatg tcttcttgga tgtgtcgaaa cgcatggaca tctttgacac
    24421 tgcttaaaaa tgacaaacct tcacttcgaa aattcccgat ataaactgct tcagtaaaag
    24481 ggagcaaagc cggagctaag ggctgatttt gccgatggat ctctttgata taaaacatca
    24541 ttttgccaga agattctgta aagattttga ctaatttatc tttttctttg taattacggc
    24601 tagataaaat caagcctttt gattctgcaa gctggctcat attctccctc ctaaaaaata
    24661 aatctggaaa agcagattct gccgatccag atcatttatg ttgcgatctt ccgcagcttt
    24721 tctcaacacg cggattttta ttcagtttat ttctatacct aatttacaag aagctcagaa
    24781 tatcagtatt cgtcttttcg gtagccgaag tcttgcagat agactttttt gtctcgccag
    24841 tctttttgaa ctttgaccca aagttctaga aagactttgt ctcctaaaag attttcgata
    24901 tcttttcttg ctttcgttcc tacttgcttc agcatttttc cgcctttgcc gataatgatc
    24961 cctttttggc tatctctttc gacaataatc gtagcctgga tatggatttt atcattctcg
    25021 tttcgcttca tcgaatcaac aacgactgcg acagaatgag gcacttcgtc tcgtgttaaa
    25081 aacaagactt tctcacggat caattcagaa acgatgaagt attcaggatg atcagtcact
    25141 tgatcatctg gaaaatattg tgggccctct ggcatttcac tgactaatac atccatcaaa
    25201 cgttcgacgt tgtttccttc tgtagcagag attggaatca cttgtgcaaa aggcatctgc
    25261 gttgaataat cttcgatgat tcccaacaac tcgtctggat ggattttgtc gattttattg
    25321 ataatcagat aaacaggaga atgcacgttt tttagacgtt caataataaa atcgtctccc
    25381 cgaccgcgtt tttgatcagc actaatcata aataagaccg cgtccacttc tttcaacgca
    25441 ctgtaagctg cttctaccat aaaatctcct aaacgatgct ttggtttatg gattcctggt
    25501 gtatcaataa aaatcaactg agcttctggt gtagtgtata ctccttggat tttatttcta
    25561 gttgtctgtg ccttgtcact catgatggca attttttgac ccacgattcg attcaataat
    25621 gtggatttcc ctacatttgg gcggccgacg attgcgacaa accctgattt atgttctggc
    25681 atatatgttc tcctttttaa ttaaacaaca aatgatatat tttagggaca aataaaatca
    25741 acccaacgat gacggtaaaa caagcggtca ctaaaactgc tccagctgcc atatctttga
    25801 tttttttccc aatcggatga aaatgaaaat ccgtaaacat gtccacgaca ttttcaaaaa
    25861 cagtattgat gatctctact atccatacga gaaaaacagc taaaagcagc cataaccatt
    25921 ctatccgatc aagttggaaa atcacgccca taaacaaagc gaggattccg aacgcaacat
    25981 gtttcctcat gttgcgttct tcctcaaaaa cagttttgac tccttggacg gcaaattcca
    26041 cggacatcag gaaatgtttg tttttctcta cgtttttatc ttttaagtcc ataggcatct
    26101 aagatctctt tctgtaaacc aaacatttct ttctcatcct ctggtgtcat atggtcatac
    26161 ccgttgatat gcaagaatcc atgaaccgct aaaaagccaa gttcccgatc atacgaatgg
    26221 ccgtaagctt ctgcttgctc tgcagcacgt tcagtagaga tcatgatgtc tcccagtaca
    26281 cgaggcaatg gattctctcc atcttcaaaa atcactggga tttcgtcttc gccctcttct
    26341 tccaaggcaa aactgatgac gtctgtcggt gcatcttttc cacggtaatc acgattgatt
    26401 acttggattg ctgcattgtc catgaaagta acagacattt ctgtttcttc tggcaactct
    26461 aaatatgatg ctgcaaattg cagcaagtcg tcgatttctt tcattttctc ttctgagact
    26521 tggtttgttt catccatgaa ggtaatatcc attatacatc gcttctttct attcttcttg
    26581 ctattcttct tgttcttctt ttatcttctc aacttccgat ttcattttag gatatttgat
    26641 ccgagaatgg aaggtactgc ttaaaccgct gatcaatgat ttttctactt tacggatttc
    26701 ttttaacgtc aatccactgt cgtccaattg tccatcggaa atacgctctt caataagatt
    26761 atggacaaaa ctttcgattt tttcgctcgt tggatggtcc attgcccgta ctgccgcttc
    26821 acaactgtca gctatattga cgattcctgc ttcacggctt tgaggttttg gtccaggata
    26881 acggaattgc tcttccgtaa cttccgggtt gcgttccttt gccttaacgt agaaataacg
    26941 catcagcgtg gttccatgat gctgtctaca aatatcgatc accatttgcg gcatattata
    27001 atcttccaat attttggcac catctgtcac atgtccaaag ataatatgtt tactgtcttc
    27061 tggcaataag aaattgtgcg gattttccgc tcctgaaggc aagttctcaa cgaaaaagct
    27121 ggcgtgtttg atcttgccga tatcatgata atagcaagct actcgagtta gtaaagaacg
    27181 tccaccgatt tctgctacag cattagcact tagattggct accatcatgc tatggtgata
    27241 cgtacctggt gcttcttcca gcaactgttt caataaagga tgattgggat tgctgagttc
    27301 atttaatacg atcacactat catcattgac catcaattca atataggggt gcagacctat
    27361 cgtcagcaag aatgaaaaca gtgcacctgt gaatccgcag actagcgtta accaagtcgt
    27421 tgcatcccca aagctcattc cttggtagat aatcaaaatg acatccatca tcacaggaaa
    27481 aataatgacc cacatagcag cggataaccc ttgttctgag atccgtttgc gtctgacgat
    27541 cgttgccatg agaccagaaa atacatagga catcaaaata actgtcagaa agttcgtgcc
    27601 aatcgaatca taaaaaatga aaagtgcgga tactgcttga aaaataccag ccatgatccc
    27661 tgctcttcga ttcaagaaaa agcttaaaac aagtggagca aaagccgcgg ggtaaaacag
    27721 cggaatataa gcagcttgtt ctgtttggaa gagttggaaa aatttcatta gtacgacgct
    27781 tactgacatt gccgtcacgt agaaaagtac gtattttgtt ctttctcctg cattttggaa
    27841 ttgaagtgaa ttataaatca gtacaccgat ttgaagcaaa acagctaaaa ccatggcaat
    27901 gagtgggaaa atagaagtcg tttgattcgt caatcctagt aattccaatt ttttcatcgc
    27961 tgaagcatca atttgatttc cttcgcgaac aataatttct ccttggaaga tcatcactgg
    28021 ttgtacagct tctcgtgcag attgttttaa ttcttctgtc tttttctcat tcaatacatc
    28081 attaactacg atgccttgat ccactaagta gcgaatcatt tgttgctgct ctgttgtgac
    28141 attcaaatat tgaatctgat cttctgcttc ttgtttaaaa gcttccaatt cgctttcacg
    28201 aacttgttta ctcatctgtt cgtcaatgag cttcaaactt tcatccctaa ctgtgtgaat
    28261 ttccgtttca gtcatttcaa atatcgtcga ataaaaattg ttcggcagtt tttggtaaaa
    28321 cgcaacgttt tctgcattca cgttttcaaa atttttcttc agtgtagcaa tccgctcttc
    28381 tgtagtaggt ttcgggatat tttcatcttc cttcgcctta tctaccttgc cattataaga
    28441 tttgttgatg gtatcattcg tcttatcgat caattcgaat aattgcttga tccgattgtt
    28501 ctggtcatct gccagatctt tttgataagt atattctgga gtcactgctt ctgctgccag
    28561 ttttcttctt tgttcggttt cttccgtgtt ctcaatcgtt ttattcgcac ggatactctc
    28621 ttctgctact tggccttctc tgaaatcaat ggccttttgt ttgacactac taaatgtaac
    28681 gccgcagaca atgataaaaa acaagaacag aaggaaaggc aatgctgcct ttccgagttt
    28741 ttcttgtagt ttctgcagtg ttttattcaa catgtgctta tcctcctaag caaagcttat
    28801 tcttgatgaa gatccgcctt ttcataagct ttgatgattt cggcaactac agggtgccga
    28861 acaacgtcac ttgcttcaaa attaacaaaa tcgatttttt tgatttgctt taatgttcgt
    28921 tctgcatgaa caagaccact tgtcgtccca cgaggcaagt ctatctgact tgtatcccca
    28981 ttgacaatca tttttgattg ataaccgaga cgggtcaaga acattttcat ctgagcgact
    29041 gtcgtgtttt gtgcttcgtc caagataacg aatgcatcat ccaatgtccg cccccgcatg
    29101 taagctaaag gtgcgatttc gatcacgcct cgttccatca atcggttcgt atgatccaat
    29161 ccaaaaattt ggtataaagc atcataaaca ggccgcagat aaggatccac tttttctttc
    29221 agatccccgg gtagaaagcc taggttttcc cctgcctcca cagcgggccg cgtcaaaatg
    29281 attttttgca cttcgccttt ttttagggca gcaattgcta atactacggc aagaaacgtt
    29341 ttccctgttc cggctggccc tacaccaaat acgatgtcat gtttggctac cgattcaacg
    29401 tatttctttt gaccgctgtt ttttacccgt ataggttttc cattacggtc tttgacgatc
    29461 tcttcctcat acatctcaac aaaataatct aatgtacctt tttgccccat tttcaatgcc
    29521 gtcacaacat ctggcgtact tacgtggatt cctcgtttga tcaattcctg taatgtccga
    29581 atgactgagg cagccaagga aatctgggat tgctcaccaa tgatctgaat gatttctcca
    29641 cgtgtatgga tggttgtttc cgttgtttcc tcgatcagtt ttatatgctt gtcgtgtgca
    29701 cctaaaagca tgctgacatc atcagcagct gtcaatctaa tctctaaaga actagactct
    29761 tccgtcaaaa atagacatcc cctttttttc gattcattct ttcctatttt accatactca
    29821 gaagaaacta tatagcaaat aagaaaaggt tgtaaaagag tcgcttaacc atacgtacca
    29881 agaaacgtta aaaaatagcc gtttccattc gctaaaggtc tcgttttgat aaaaagaagc
    29941 tgagaatgta agttatatga aagtggagaa caaaatattt cgtttcattc aacaagtatt
    30001 ctctaggtat ttttcctgtt tcaaaaaaag aaaacaaaat agttaaaata ttcttgcatt
    30061 tcaaaaaaaa caggtgtatt attacgtcaa caaataaaca tacagcaaag cgtcgaggaa
    30121 aacagtaggc tattcaacga tttattccca gtgagtcatg taagtgagaa atgacaataa
    30181 atcgaataga cgaacatcat ttccgagtca atgtcgaaaa cgtagatcat tgtggctgcc
    30241 tccattatca ggctagcgga taactttatc aaaaagcgtc cgtgaatgaa gaagcttttt
    30301 taagcgaaaa aaggtggtac cgttctagaa tctagagccc ttttcccaag tggaaaaggg
    30361 ctttttttta ttttaaggtg gtggttttca tggaatctga tattagtggc attactaatt
    30421 gctgcaacgt ttatatcgtc aatcaaaatg ataattattg gaggaaaaat ttatggaaga
    30481 aacaaaaact tattcatgga aacaactatt gatggtcagt tcacttatct tcgggatgtt
    30541 cttcgggtca ggtaatctaa tctttcctgt ccacttaggt caaatggctg gcgcaaactg
    30601 ggtcagtgct ggcgtaggat ttgctatctc aggtgctctt ttcccattac tagctatctt
    30661 agctgtagta gtgacaaaaa gtgatggtct gtatgactta gctaaacctg tcggaaaatg
    30721 gtatgctgcc ttgttcttaa tccttgttca tttgacgatc ggaccatttt tcggtacacc
    30781 acggacagct gctactgctt ttgaaatggc tgctaaacca tttttgcctg aaaaatataa
    30841 ttcattaggt atgtttttat tctctgctct tttcttttta cttgcttatt tccttactgt
    30901 ccatccaaca cggttggtca aatacgtcgg aaagtatcta aactccttgt ttcttgcatt
    30961 attagcaatc atttttgtcg tttctttatt ccatccaatg ggaaatctaa atcaatctgc
    31021 tgcagatact tatcaaacaa acgctttaac aaatggtgtc ctagaaggtt ataacacggt
    31081 tgatgcagta gctttgcttg ccttaagtgt cacttttgtc catgcagtcc gtgaccttgg
    31141 tttcaaagat aaaaaagtca cagaattaac ggcaaaagct ggtagcctga gcgttgcgct
    31201 agaagtcatg atctattttg gacttgttct tctcggtgcg atgagtttga ataagatgtc
    31261 tttatcagaa aatggcggaa ctgcactttc tcagatcact aatttttatt taggtaactt
    31321 cggcgctagc ttcttaggag tgatggtcac attaggtgtc ttcactaccg ctatgggact
    31381 cgttgtttct tttgcgcaag atttccataa actgttccct aaagtcagtt atatgacatg
    31441 gctgcggtta acgactttcg tctcttttgt cgttgcaaat gctggtttag acaatatcat
    31501 ccaatggtct ttaccagtat tgatgctttt gtatccattg tcgcttgcgt tgatcttgct
    31561 ttccttaaca gcaaaatttt tccaaaagac accatttgtc tatcaagtaa cgatgttgtt
    31621 tgctgctgtt cctgccgtat tggatatgct ggcaaattcg cctgctttag tgagtcaaca
    31681 aagagttgta gcaagcatgc tcgaatttta tcatcatcac gttccttttg ctgcattagg
    31741 acttggctgg atggtcccaa cgttacttgg ttacgctggc agcctactgt tttattacgc
    31801 ctatcgccta tcagggtata aacaagaagc aaatgaacta ccagaagaat aaccaaatca
    31861 aacacaattt aacataagaa atattaaaca ggaaaaaacc agctagatga aagaatccta
    31921 ttctttcgtc tagctatttt ttagttctct tttttacgcg cacaaaaaaa ctgcggacaa
    31981 tgattgtccg cagtttaaat gggctctata atatctagtg ttggtgacgc cttctgttgc
    32041 caatactttt tcttttttct aataaacgca aacagacacc tt
//
LOCUS       DBBGRF010000033        30114 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000033 DBBGRF010000000
VERSION     DBBGRF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.033"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(203..1654)
                     /gene="cls"
                     /locus_tag="ACIZD4_001708"
     CDS             complement(203..1654)
                     /gene="cls"
                     /locus_tag="ACIZD4_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGC5990646.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            1996..4662
                     /locus_tag="ACIZD4_001709"
     CDS             1996..4662
                     /locus_tag="ACIZD4_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC5990647.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5026..5778
                     /locus_tag="ACIZD4_001710"
     CDS             5026..5778
                     /locus_tag="ACIZD4_001710"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC5990648.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(5800..6954)
                     /locus_tag="ACIZD4_001711"
     CDS             complement(5800..6954)
                     /locus_tag="ACIZD4_001711"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGC5990649.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            7139..9580
                     /locus_tag="ACIZD4_001712"
     CDS             7139..9580
                     /locus_tag="ACIZD4_001712"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGC5990650.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(9910..10614)
                     /locus_tag="ACIZD4_001713"
     CDS             complement(9910..10614)
                     /locus_tag="ACIZD4_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990651.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(10801..11046)
                     /locus_tag="ACIZD4_001714"
     CDS             complement(10801..11046)
                     /locus_tag="ACIZD4_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990652.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(11063..11914)
                     /locus_tag="ACIZD4_001715"
     CDS             complement(11063..11914)
                     /locus_tag="ACIZD4_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGC5990653.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            12080..13084
                     /locus_tag="ACIZD4_001716"
     CDS             12080..13084
                     /locus_tag="ACIZD4_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGC5990654.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(13325..13681)
                     /locus_tag="ACIZD4_001717"
     CDS             complement(13325..13681)
                     /locus_tag="ACIZD4_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC5990655.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            14049..15236
                     /gene="tuf"
                     /locus_tag="ACIZD4_001718"
     CDS             14049..15236
                     /gene="tuf"
                     /locus_tag="ACIZD4_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGC5990656.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(15424..18015)
                     /gene="mprF"
                     /locus_tag="ACIZD4_001719"
     CDS             complement(15424..18015)
                     /gene="mprF"
                     /locus_tag="ACIZD4_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HGC5990657.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(18041..18802)
                     /locus_tag="ACIZD4_001720"
     CDS             complement(18041..18802)
                     /locus_tag="ACIZD4_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC5990658.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            18969..19601
                     /locus_tag="ACIZD4_001721"
                     /pseudo
     CDS             18969..19601
                     /locus_tag="ACIZD4_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            19660..20520
                     /locus_tag="ACIZD4_001722"
     CDS             19660..20520
                     /locus_tag="ACIZD4_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGC5990659.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLCGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            20705..23020
                     /locus_tag="ACIZD4_001723"
     CDS             20705..23020
                     /locus_tag="ACIZD4_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC5990660.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            23202..25043
                     /gene="dnaG"
                     /locus_tag="ACIZD4_001724"
     CDS             23202..25043
                     /gene="dnaG"
                     /locus_tag="ACIZD4_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGC5990661.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            25067..26176
                     /gene="rpoD"
                     /locus_tag="ACIZD4_001725"
     CDS             25067..26176
                     /gene="rpoD"
                     /locus_tag="ACIZD4_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGC5990662.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            26396..28495
                     /locus_tag="ACIZD4_001726"
     CDS             26396..28495
                     /locus_tag="ACIZD4_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HGC5990663.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            28691..29554
                     /locus_tag="ACIZD4_001727"
     CDS             28691..29554
                     /locus_tag="ACIZD4_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HGC5990664.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            29659..>30114
                     /locus_tag="ACIZD4_001728"
     CDS             29659..>30114
                     /locus_tag="ACIZD4_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGC5990665.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFYGICQECYEKEK"
BASE COUNT        10010 a         5314 c         6264 g         8526 t
ORIGIN      
        1 gaaagaggtc gtgagcctgc cgtccagctc cgagtcacaa ggaacaagtt caaaaaacag
       61 cttctcatgt ttgttgaata ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
      121 tgttcggaag aagggactgt gacaagattt ttgtcacagt ccctttaatc ttagtatatt
      181 tttctctact tgaataaaaa aattatagga ttggagaaaa taatcgagaa atttgttgct
      241 tgaataatag ccagttagac atttccttga ctgtttcagt tgtcatggat gaacaatgtg
      301 tctcatcttc tttgaactga gtagcaagtt cttctaaaaa ctcaggatcg taaatgacag
      361 cacttgtttc aaaattcaat cggtagctac gaatatcttg atttgctgaa cctaccatgc
      421 agatttcatc atccattatc aatgtttttg catggaggaa gccgttctca tagacaagga
      481 tttgtacatt ttccttgatc agctgccgag cataatattg tgttgctcga taaataaaag
      541 gatgatccgg tttgttggga atcatgattt tcacatctac accagaggca gttgcgattt
      601 ttaaagcagc aatgacactt tcatcaggaa caaggtaagg tgtctgtatc caaacacgtt
      661 ttttagcaga agtaatcaat ttgataaatg aaagcttgat ttgttccctt tcgttattcg
      721 gtccgcttga aacaagctgg atggatgtat cagcaagctt agattcatct cgatctgctt
      781 ttttaaagaa ataattcaaa tgatagccga cctttttttc ttcaggtacc gagacgttcc
      841 agtctgttaa gaagcgaagc tggagcaaag aagaagcggc accgaaaatc cgtatatgcg
      901 tatcgcgcca atagccgaat ttttttgttg tatttacata ttgattggca atattgaaac
      961 caccggtata actaatcttt ccatcgatca caacgatttt tcggtgatca tggtaattca
     1021 atcggaaacg aagtaatgcc ctttgtgagg taacaaatgt atggacatgt ccaccatttt
     1081 tgattagacg attgaaatct tttgcttttg tgccatgaga gccaaatgca tcatataata
     1141 ttcgaacttc cacgccttct gcggcttttt cttctaaaac atgtaagact tgctggccga
     1201 tattatctgt cacaaatgcg taatattcga tatggatcga atgtttggct ttttttagat
     1261 cttgaagcag tgaatccaat ttctcttgtc cgtctgtgag aagagtgaca gaattcattc
     1321 ttgtcagcgg catacgattt aatgaagaga agaagtcaac aaattgctgt ttgtctttat
     1381 cgcccatgtc aggatcgtaa tgttcaatgg tatctcctct aaaagactga aagttttcta
     1441 attctttcaa gtcactttgt cggagataga attttttctt atccgttaat ccacgtccga
     1501 aaaataaata taatacaaag cccaccccag gaagggcaaa caatactaag agccatgccc
     1561 aaatggctgc tacatctcgg ggtttgatca aaatagccac caaagcaata agtgcattta
     1621 atagataaag ggcggttata atactagata ccacaaaaat gttcctcctt acatacaata
     1681 acattagtat agcatgatag aagaaagaag cctaccaagg tgaatatact tttcactcct
     1741 ttcatgaaaa tgtaggtaaa tcgggctaaa gtagttgctt tttgtaggtt aataagggta
     1801 ggatattagt acagttgaat atctccttag gggagtaacc ggcaacgttt gttgcgataa
     1861 tatcaacagt aagttaacca aatggttttc tggtattgta tgaaatggtg agacctaaga
     1921 caaatgcgta tttgtcttag gtctcttttt tttcagacag gactagggcc aagatcaaaa
     1981 aatgggggat gaaatttgga aaacaaggaa caagcacaac aagcggtcta taaagaaacg
     2041 atcgactcgt tgatgcagca aacgcagagc tcaaccgatg gattgagcac cacgcaagcg
     2101 aaggaaaaat tagaaagaga tggcttgaac cagctaaaag aaaagccgaa gaagccaact
     2161 tggaaattgt tcttagaaac tttcaaagat gcaatggtta tcgtattgct gattgtcgca
     2221 ctgattcaga tggtcatggg tgactacatc gaattcttag ttatttttgc agtattgatg
     2281 ttgaattcta taatcagtgt tgtccaaaca aaaaaagcag aaggttcttt agaagcgttg
     2341 aaaaaccttt cagcgcccga tgctcgagtg attcgtgatg gtaaggaaaa aacgattccg
     2401 gcaaacgaac ttgtggtagg agatatcgtg ttgttagacg caggcgatta tgtacctgct
     2461 gatggacgtt tactagatgc gggatcatta aaagtagatg aaggtatgct gacaggagag
     2521 tcgacttctg cagaaaaaga agtaacggat atcacaagta cggtaccaat cggagatcgt
     2581 acaaatatgg tattcagtgg aacgatcgta acttacggac gcggtaaatt cttagtgact
     2641 tcaactggga ataatacgga gatcggacaa gttgctggcc ttttggaatc aacaactgag
     2701 caagtcactc cgttacaacg aggtctggat aaattcagta aaaaactaag tttggctatt
     2761 ttggcattgt ctttattgat tttaggtatc caactgtttc gtatttatct tggagaaggt
     2821 acaggagata tgactgcaga tatcgtcagc gcagtgatgt ttgccgtagc cgtagccgta
     2881 gctgctattc cagaagcatt acagtctatc gtaacaatcg tgttatcttt gggaacgaat
     2941 aaaatggcaa aacgtcatgc cattattcgg aagcttccag cagttgaaac acttggttcg
     3001 acaagtatca tctgtacaga taagactggt acattgacac aaaacaaaat gacagttgtt
     3061 gactactttt taggtaatgg cgatactggg gatttcacaa atgacccttc aaaatggaca
     3121 gctgacgaac gtcgcttgat cgaaatcagt gttttagcga atgatgcatc gatcagtgaa
     3181 gacggtacta aattgggcga ccctacagaa gtagcgttta tcgactttag tgaaaaatta
     3241 aaccagcctt atcaggaaat ccgaaacaac tacccaagac aagcagaact tccttttgac
     3301 tcagatcgaa aattaatgtc tactggacac acaattgata acaaaaatta cttgtttgtt
     3361 aaaggcggac cagatatcgt cttccaacgc agtaaaaaag tattgctaaa tggtgaagtc
     3421 gttccgatga cggatgaatt gatgaaaaaa ttccaagagc aaaatgaagc tttttcaaca
     3481 cgcgcattac gtgtactagc ttttgcttac cgtccacttg ataattttga tttatcattt
     3541 gaagatgaag acgatttgat ccttgttggt ttgcttgcta tgatcgatcc tccacgtgct
     3601 gaagtgactc aggcggtaac agaagcaaga agtgcaggaa tcaaaacaat catgattact
     3661 ggtgaccaca aaacaacagc tgttgctatc gcaaaacaaa tcgggatttt tgaagaagga
     3721 aacctggctt tgaccgggac ggaactagat gaattgacag aagatcaact aaacgaagtt
     3781 ttagaaaaag tcactgttta tgcacgtgtt tcacctgaga ataaaattcg tatcgttcgt
     3841 gcttggcaaa ataaaggtca tatctcagct atgacaggtg atggtgtaaa tgacgcacca
     3901 gcattgaaac aagcagacat cggaattgct atgggaacgg gtacagatgt ggcaaaagat
     3961 gcagcagcga tggtattgac ggatgataac tttgcttcta ttgtcagcgc agtagaagta
     4021 ggacgtaatg tgtttgataa tatcaagaaa gctatttctt atctatttgc aggaaattta
     4081 ggtgcgatca ttgcgatcat ctttgcctta gttgctgact ggtccaatcc atttacagca
     4141 ttacaactgt tgttcatcaa tttagtcaat gattcactgc cagcaattgc attaggtaca
     4201 gaaaaagctg aacctgctac gatgaaccgc ccgccaagag atccaaattc aggaatcttt
     4261 acggacaaaa cattgatttc tgtaacgtat cgtggtgtgc tgattgggat tgctgttatc
     4321 tttgctcaat ggcttggcat gcagcattca cctgaattcg gtgtagccat gtcattttca
     4381 acattgattt ggtgtcggac attgcaaaca ttcccagcac gttcaaacac acaaacagct
     4441 atccaagcag ggttcttctc taacagaagt gtcttactag ctgtagttgt atgtagcgcg
     4501 ctttactgct taacaatgat cccaggactg aaagaagtct tctctatccc atcagcattt
     4561 ggattgacag aagtctttac atgtatggga atcgcacttg tgacaattgt tttgatggaa
     4621 atcactaaat tgatcattgt acgagtacaa ggaaataaat aaaacgaatc aacgaggttg
     4681 tgagcctgcc gtttaattct gagtcacaag gtgcaatttc aacaaacagc ttctcatgtt
     4741 tgttgaatat tgtgacttgt gaccgaagag ttggcaggag aacaccgttt aaggaagaag
     4801 ttgtaaaatc agcattttga gctaatactg agggtcatct gattggacac tgtttattcg
     4861 gaaagaggga ctttgacacg actttggtca cagtcccttt ttttatttat gatagacgga
     4921 aagccaatca ttttattatt catcaaaaga gatagaatag ataaaagagg agaatgattt
     4981 attccgaaaa gtgaaaacat ataacaaaaa attagaggaa atcaaatgaa tgaaaaagaa
     5041 tgggatgaat ttgctgaaga atattatgaa atccagcaag aatcgcaagt aactattgct
     5101 gaagatgtaa aaaattatct gaaaacggag aaagtcctgc ctgctgaaac agcagcagac
     5161 gttgctggag gatctggcag atttctttcc ttagcaaaag aaattaatcg ctatgatttg
     5221 atcgattttt cttcaggaat gctagaaaat gcaaaaaaag aagcagaaaa aaatgagttg
     5281 ccaaatgttt cctttatcaa acagtcgtta gaagaattta tccaatcaaa tgagacatat
     5341 gaaatggttt ttacagcagc aaatccagca ttggtacatc ttattcaatt agaaaaattg
     5401 atgaaaaagt caagcaaatg gtgcgtgata atcagagtag tggaatcaat cgatgatgtt
     5461 ttttatccta tcgaaaagca actaggaatg atagaagaag atcctaatac atcgccagtt
     5521 gtaatggatc aatttgaaac atacttaatt gatgaaggat tcaaagtgaa gaaaaaagat
     5581 tttacttatt ttacacagga atcaattact gaagaattga tgaagctata ctatgacgcg
     5641 tacgcaaaag atcctgttgt gaccaggtac attcgcaaac tattcagtga aaaacgagaa
     5701 atccttagta cgactaagct gacctataga ctgctccttt ggtccgcaga taaaaaaaga
     5761 acctttcacg actcgtgaag ggttcttttt atgattttat tatattttgt agtaacgaat
     5821 atcattttcg atctttgtaa tcgaaaaagg tacatctgaa gtatattctg cacattctcc
     5881 gtgttcagga agcgtctcac tgaaaatcgt ttcatattcg tcaacagtga tccgtgttcg
     5941 agaatctagc atctcttgat gagattgtgc gaagagatat tcttgatagt tttcttccag
     6001 ataacctgta aaaaattcac ttactgcacc agaaccgtag ctgaatagac cgatgcgatc
     6061 tcctggctgt agtgatttcg aattttccag tagagaagtt agccccaggt ataatgaacc
     6121 agtgtaaaga ttaccgattc gtcggctgta acggatgctt tcttcatagc gagccataag
     6181 acgttcctga ttttcttcgt ctgtttggtc taatacgctt tgcaatgcct tttttcccat
     6241 cttagtatac ggaatatgga aagcaatcgc ctgataatct tcgagtcctc gacccgacaa
     6301 ttctttatgt cgattccaaa ctttttggaa tgattcgata tacgtagaat tagataaagg
     6361 accatcaaca acaggaaatt cgctataatc tggacgccag aaatcataga tatcttctgt
     6421 cagaaatacg ctgtcgtctt caatcgataa aatacgcggg ttttgagtga tcatcatcgc
     6481 aacagcaccg acaccttgcg tcacttcacc accgcttgcc aagccgtaac gagcaatatc
     6541 acttgctatg actagtactt ttcgttctgg atgatttttg acatattctt tcgccatgtg
     6601 caaagctgcg gtgccaccgt agcaagcctc ttttacttca aaagaacgag caaaagattg
     6661 gattttcagt aaatggtgga taattaccgc actcgctttt gaatgatcaa tcccggattc
     6721 tgttccgacg atgaccatgt cgattagctc acggtctttt tctgttacga ttttgctggc
     6781 agcatttgct cctagtgtaa tgatgtcttc atttgcacga ttgactgcca tttggtcttg
     6841 accaatccct atatggtatt ttgcaggatc atccccacgg ctttctgcca actctgtcat
     6901 atctaaatat aaattaggaa taaaaaagga aagacgatca atccctattt tcatttcaac
     6961 acctctttac ttatgataaa aaacttactt tactaaggta tcataaaaag attaaaagaa
     7021 atataaaaaa gagaatattt aaggattgtt aaaatttaat cttagaaaaa aataactgga
     7081 acaagagcta tttgttttta cagcaaagaa tggtatattt ttgtaggagg tggcttactt
     7141 gaaagaagtc gttatgatag atgctgcaag aacgccgata ggaaagtatc gcggaagttt
     7201 aagtccattt actgcagttg aattaggcac acttgtgact aaaggattat tagataaaac
     7261 aaaactgaaa aaagataaaa tcgatcaagt aatatttgga aatgtcctgc aagctggtaa
     7321 tggtcaaaat gttgccagac agattgcttt gaacagcggt ctccctgtag atgtcccagc
     7381 aatgacgatc aatgaagttt gcggatctgg tatgaaagca gtgatcttag cacgccagct
     7441 gatccaatta ggtgaagcag aacttgtgat agccggcgga acagagagta tgtctcaagc
     7501 acctatgctg aaacagtatc agtcagaaac aaatgaatat ggtgaaccaa tttccagtat
     7561 ggtcaacgac ggattgactg acgcattttc aaatgcacat atgggattaa ccgcagagaa
     7621 tgttgcaaca caattttctg tgagcagaga agagcaggat cgctatgcct tgtcgtccca
     7681 gttgaaagca gcacatgctg tcgaagccgg tgtattttct gaggagatca tcccagtcaa
     7741 gatttctgat gaagacgtgt tatctgagga tgaagcagtt cgtggaaata gtacattgga
     7801 aaaactgggc acgttacgta cagtattctc agaagaagga actgtaacag caggaaatgc
     7861 ttccccgttg aatgacggtg cctctgtggt gatccttgca tccaaagaat acgcagaaaa
     7921 taataatctg ccttatttag caaccatcaa agaagtagcg gaggtcggta ttgacccaag
     7981 tatcatggga atcgctccaa tcaaagccat tcaaaaattg acagatagat caggaatgaa
     8041 tttatcaaca atcgatcttt ttgagatcaa tgaagcattt gcagcttctt ctatcgtagt
     8101 tagccaagaa ctgcagttag atgaagaaaa ggtcaatata tatggaggag caatcgcatt
     8161 aggccatcca attggtgcaa gcggtgcacg tatcttgact acattagctt acggattgct
     8221 tcgtgaacag aagagatacg gtattgcttc attatgtatt ggtggaggtt taggcttggc
     8281 agtcttgtta gaagcgaata tggagcaaac acataaggat gtgcaaaaaa aaaagtttta
     8341 tcagcttacg ccatctgaac ggcgcagtca attaatagaa aaaaatgtat tgacacaaga
     8401 aactgcgttg atttttcagg aacaaacact ttctgaagag ctctccgatc acatgatcga
     8461 aaaccaagtg agtgaagtgg aaatcccaat ggggatcgcg cagaattttc aaatcaatgg
     8521 caagaaaaaa tggattccga tggcaacaga ggaaccatct gtcattgcag ctgcaagtaa
     8581 tggtgcaaaa atctgtggaa atatctgcgc agaaacacct cagcggctga tgcgagggca
     8641 aatcgttcta tcaggaaaat cggagtatca agcagtgatc aatgcagtta atcatcgaaa
     8701 agaagagctg attctttgtg caaatgaaag ttatccttca atcgtgaaac gcgggggcgg
     8761 tgttcaagat atctctactc gggaattcat ggggagtttc catgcatact tatctattga
     8821 ttttttagtg gatgtaaaag atgcaatggg cgctaacatg atcaactcga ttcttgagag
     8881 tgtggcaaac aagttacggg agtggttccc tgaagaagag attctattca gtattttaag
     8941 taattttgct acagaatcat tggcttctgc ctgttgtgaa atcccattcg aacgcttagg
     9001 gagaaacaaa gaaatcggtg aacaaattgc caaaaaaatc caacaggcag gggaatatgc
     9061 gaagcttgac ccttaccgtg cagcaacgca caacaaaggg atcatgaatg gtatagaagc
     9121 tgtagtggca gctacaggaa atgatacacg tgcggttagc gcttcgatcc acgcctacgc
     9181 ggcaagaaat ggattatacc aaggattaac agactggcag atcaaagggg ataaactagt
     9241 tggaaaacta acggtgcctt tggctgttgc cacagtaggc ggagcttcca atatcctgcc
     9301 aaaagcaaaa gcatctttag ctatgttaga tattgattca gccaaggaac tagcacaagt
     9361 aattgctgca gtagggttag ctcaaaacct ggctgctttg cgtgcattag ttacagaagg
     9421 aatccaaaaa ggccacatgg gacttcaagc tcgttcatta gcgatctcaa ttggggctat
     9481 tggtgaggaa atcgagcaag ttgcgaaaaa attacgtgaa gcagaaaaga tgaaccagca
     9541 gacagctata caaatattgg aaaaaatccg ggaaaaataa aaaagcaata tctttagaag
     9601 aataaagcaa gatttacagt tattttattt actgcagatc ttgctttttt ctctatcaga
     9661 aaatatgttt attattagaa ttttttatag ttaaggttag gcatcttaag aaatcaggca
     9721 actccaagat atcttcaggt agaagagaag tcgcctaaca ttgtaggatc ataggtgatt
     9781 tgttggacag gtcaagctga tatttgagcc tgatgttaga aggaatttct ttttacttgc
     9841 tgtagaaatt attatatgac taaaaaggct gggattttaa atcccagcct tttatgacaa
     9901 atagaatttt tatcgatcag taatcgctgt cgctgcaaat tgttcgatca aaggaatcaa
     9961 agtcaatttg actttgtatt tccgttcgag tgctttttcg ataacgaact cattttcagt
    10021 agtcatagaa atagttgcta atttacgagg ttcatcagca tttttttcat taataactac
    10081 ttcatgttca ttttgttctg tgtaaaattt aggatactca gcaacggctt ttgaaaaatc
    10141 agcaaaactt aaagcggcat tcgtatcagt tgagcgtgta ttttcagttg tgtccgcttt
    10201 tggtttttcc gttttttctt ctggcacact gactgtttct tctgtaactg gtgtcgcaac
    10261 agcttgcgca gttggttcat cgtttttcaa tcgttgatca ttccagtaag acacgatttc
    10321 aataagaaga ttgtcacgga atcgttcgaa aatcccgttt tctcctgaac gaattctctt
    10381 taatacagta ttgaagttgt catcgattgg cacgttgatc cgtgtatctt catttgtttt
    10441 cccagctaat ccgatcgtta agatttgacg gtttttggga tcaagcatga cttgtaacgg
    10501 caaaccataa cgtcgcaagc tctcttcttc tagagaacgg aataattgtc ctcttacacc
    10561 atccaatgaa ggacggaatt gatttaataa tttttgtttc tgttttttct tcatatgttc
    10621 tctccttcgc tcataccctt tcgattataa gaaaaaaaca gccaaatgaa aaggagtaat
    10681 gcaaaaaaac ttgcgtatac gcaaattaca acagaaaaat ttgcgtattt tcccgttttt
    10741 tgaaagaaaa ataaaaaatg gaacggatta tgtatatata cataatccgt tccattcttt
    10801 ctattttttc ggtatcaagg caaaaacagg tagttcaggt gaataaatga cttcatgttc
    10861 gtgccagggt ttgaccatta gcgaatgatc gaaccgtttt ttcagttctt cgatgatttg
    10921 atcatgtgtc cagtttcttg caggaaaatg ttggattttc tctgcatcga tcaaaaagac
    10981 aaaatcggaa tgaaaagtct gggtaacttc ttccgagaga gaattcaagc gttcgattgg
    11041 atccataaaa tcacctttcg acttaaaatt gggtagtatc tgggtctttt gctttgccga
    11101 ctacaccatc taactgatcg atttgtttca tttcttcttc tgttaattca aaatcaaata
    11161 attcagtatt ttctttgatt ctgcttggtg tcactgactt aggaagagga aggaattcgt
    11221 gttgcagcga ccaacgcaaa gcaacttgtg caatcgtctt gtcatgtgct tcagcgattt
    11281 gtttcatttc aggcacatcg aagattttac cagtgcctaa tggactatat gcttcgagga
    11341 tcatatcatg tttttttgca tactcaacta cagttgtctg taattcgcct ggtgcaagga
    11401 aaacttgatt gaccatcggc ataatttttg ctgtttttgc tagtgtatct agatggtggg
    11461 gtaagaaatt gctcacaccg attgctttga ttttacctgc ttcatacagt tcttcaaatg
    11521 ctcgccatgt atctgcattt gcttgttccc aattatcacg aaaagcaaca gggtttggcc
    11581 agtggatcaa aaacagatct aaataatctg tttggagctt cttcaatgat tcttcaaaag
    11641 aagacatcac aagttcatag ctgtggtttg cattccataa ttttgttgtc aagaatatct
    11701 cttctctagg aattccactt tccttaatcg cttggccgac gctttcttca ttcttgtatc
    11761 cttgggcagt atcgatatgg cgataacctg cagccagcgc ttctttaaca gaggaaacag
    11821 cgacatcccc atcaggtgtt tgccatgtgc cgaatcctac taccgggatt tcgtaaccat
    11881 ttgatagacg ataagtgctt gttaatgaat tcatactttc agctcctttt ttattcgttc
    11941 aactataagt gtagcgcatt tttcgaaaaa aagaatccat tttgtttcta ctcttgaaat
    12001 ttttgtttaa aagaaaatga ttttgattct ggtatttttg attttttttc cgtaaactaa
    12061 gacagaaggg aatgagaaaa tggatatcta tttaaaaaaa gcaattctgc atattattga
    12121 cagagaaact ggttctccag tcttttcaca aaaagagctg gatctgacaa aagaatatat
    12181 tcgtgatttt cttcaaaaga agatccaaaa aatctcttct gctcaaacaa aaactggaca
    12241 actagcagaa gaaagcatga tcgttgaatc acttaaaatc gctcaagaaa attttgtgga
    12301 agcaagtgaa gcaatcgttc agcggtggtt cgatatctac caagaaagtg aagaagcacc
    12361 tagtgcagat gtatttgttg tcttgtatga attagataca gtgatgtact tatctttatt
    12421 gaaagtcaat tatcgtgagg cttacactca ctttgttgaa gcagacgaag cagggatcga
    12481 caaccgcttg attttgaatc gagcaattct aggggcgaaa acacaaaaag cagatgaagc
    12541 attcgctgtg aatttgactg attggaccta cgaattaatt gaaaaaaaat atgagttttc
    12601 tggcaaaaaa gagctttatt tttctggaag agtgatcgaa agtgttcctg caccttcttt
    12661 agaagaaaat gtaaaagtga tccaaaaagt agccaagcat cttggaaaaa aatttgagac
    12721 agaagaattt gatatcatgg ctgatttgaa agaagctgtc tatgatacga tagaagaaaa
    12781 aggtcggttg gatcatgaga tgattgcgga aaaagtcttc aaggaaaaca tcacggcaaa
    12841 aatggctttt aaagaagaag tacaagagca aggatttgtc ccagaagcac ctcctgtaaa
    12901 agaagtacaa gaaatttctg agaaaaaatt tggaaaacaa aaattcaagc tatcaaacgg
    12961 gatcgaactg atcgtaccag tagatgtata tcgcaaccca gatttgattg aatttgtgaa
    13021 taatccggat ggtacgatat ccgtgatgat caaaaatgtg gatgaagtat tgaatcgttt
    13081 ataaaaatga ctagaatatt aggtgttcaa gtaccagtga tcagttaaat gaattgtgtc
    13141 aagagaagga tcggaaaaga cgaatataac aaaaaaagag cgtgagacaa aagtaaagaa
    13201 cacttttgtc tcacgctcta aacacgtata aacggcggaa gcagaagcaa ctccttctta
    13261 tttcttggag ttaaacgctt ctgtcccagc ctctttttat ctaataaaat tttaagacca
    13321 tttactaatt atcgattttt tctgccgcat ttttaggcac ttcagaagcc tttatttctt
    13381 cccagcttaa tacaccttta cgaggattga ctttgagttt aagatacgca ttcatcttta
    13441 atggatgttc tctttcttcg cgaagcgtca cctgtttttt ttcaccatct ttattataag
    13501 ccgcttgctt gtaggtataa gtcgtgaatt tctctccgtt atctgcttgg gtagctgaca
    13561 tttcgccatt cgtcgtgatt tttgtataat aagcttcgcc gccgtaaaaa taatgataag
    13621 ctgcaaaact tccgccgaga aatatgccta aaacgacaag tacgccaatt aattttttca
    13681 tgtacttcac ctctttcctt attattaacg aaatagaaga tttcgtctat tgaaagttgt
    13741 tggcaacagc tgaattttaa acttttcctc attttgttct tattgcttca aaagaaagtt
    13801 aaggactatc ttgaagtttt tctcaaaaaa cacatttttt tatttataaa aggtactttt
    13861 ttcgcgtata agacagacga gtgctcttag ttgactttga ccaatattga cgtataataa
    13921 gcttagttcg aatcttacaa aaagtaagtc ggacgtattc tttttgattt agtcaaaaaa
    13981 agactataat aaaaaggtga gagctgaaat ttttcagtga tctatattat ttaggaggtt
    14041 tgtaaattat ggcaaaagaa cattatgaca gaagtaaacc acacgttaac attggtacga
    14101 ttggacacgt tgaccatggg aaaactactt taactgctgc gatcactaca gtattaggca
    14161 aaaaaggcct agcaaatcct caagactatg ctagtattga tgcagctcca gaagaacgtg
    14221 aacgtgggat tacgatcaat accgcacacg tagaatatga aacagaaaaa cgccactacg
    14281 cgcatattga tgcaccagga cacgcggact atgtgaaaaa catgattaca ggggcagcac
    14341 aaatggatgg tgcaatctta gttgtttctg caactgacgg tccgatgcct caaacacgtg
    14401 aacacatttt attgtcacgc caagttggtg taaaatacct gattgttttc ttgaacaaag
    14461 ttgatttagt cgatgatgaa gaattgatcg atttggtaga aatggaagtt cgcgagttat
    14521 tgagcgaata tggtttccca ggcgatgaca ctcctgtgat caaaggttcc gcattaaaag
    14581 cattgcaagg cgatccagat gctgaagctg ctattatgga attgatggat acagtagatg
    14641 aatatatccc aacaccagaa cgtgatacag ataaaccatt actattgcca gtggaagacg
    14701 tcttctcaat tacaggtcga ggaactgttg cctcaggtcg tattgatcgt ggtgctgttc
    14761 gtgtcggtga tgaggtagag atcgtaggga tcaaacctga aacacaaaaa gcagttgtaa
    14821 caggtgtaga aatgttccgt aaaacgttag attacgggga agctggggat aacgtaggcg
    14881 tgttgttacg ggggatccaa cgtgacgata tcgaacgtgg acaagtactt gctaaaccag
    14941 gttccattac tccacataca aaattcaaag cagaagtgta cgtgttgaca aaagaagaag
    15001 gtggacgtca tactccattc ttcaacaact atcgtccaca gttctacttc cgcacaactg
    15061 atgttacagg aacaatcaca ttgccagaag atacagaaat ggtcatgcct ggtgacaacg
    15121 tgacgattga tgttgacttg atccatccaa tcgctgttga aaacggaacg acattctcaa
    15181 ttcgtgaagg cggacggaca gtaggttcag gtatcgttac agagatcgaa gcataagaaa
    15241 cgcgactcga atattttggt aatgaaaaat gtttaaaata aaagagcggt ccaaacagga
    15301 tttctgtttg gaccgctctt tgttcttcaa ttgtataaga agagattgta gaagcatgaa
    15361 ctttcgtttt acttcagtct cttttattca tcatgagagt gttcatctat cggtatgcag
    15421 tttttaatac tttcttcgta tccatttttt caaaccactt attctacctt gtgtctgctc
    15481 aactggcgca ttatcaataa tcagcaaagc aatcataaca tatgcaatcc aactatctct
    15541 agaatataga gtataacgtg agacccagtt tgtagcgtac ttgcttttat attctcttaa
    15601 tccatggaaa gaataaaaat gagaaccaaa ctcgtaaacc aagtatgcaa tcctttcctg
    15661 taaaaaactc tttctggaag ttccgacatt tgaaagaggg gccatcccta aattgaacca
    15721 ttggatatgt tcttctttca tataggcaaa caaatgcaag aacaagaaat ccatactgcc
    15781 agaaggtgct tttttagaat catatcgcat cagatcaatc gttcctactt tattgttcgt
    15841 gtaagtaggc atgatcgttg caaaagcgac aatttcttct tgggtatttt tgacaactgc
    15901 aataggcgct ctttgtagat aatcttcaga gaaaaagcct aaagaaaacc ctttttcctt
    15961 tcgtgaaccc aaccaattat cagagatatt tttgaaagta ctcatttgct cagtagaaaa
    16021 tggtggttgt aagacatcaa atgtaaatcc ttctcgttcg atccgattca agacagcacg
    16081 agtgcccttc atttttttcc ctgaagttgt aaaactattc aggtctacat aagcttcttc
    16141 ccccatctta atgaaatcgt agccgaattc atgcaaaatc ataacaatct cttcgcttgt
    16201 ttcgtagaaa actggtaaat agcatagtcg atctgtttct tcgataaaag cttcgattgc
    16261 ttctggaaaa tcttctttct taccagaagg atcacccatt acaatacatt tattattgaa
    16321 gcaagcgaat tggagaagaa cagttggttc accgtctttt tcataggcaa acatccgctt
    16381 atcttttaag aagatcaatt gactatcgga gtttcctcca taagttgtaa ggatcttcag
    16441 ggccttttct tcattaaagg cttcgccaat ctgtttcttt tctccttgaa ggaaatgaac
    16501 aaatagaacg atcatgaaac taacagcgat gatggccaac aatcccgaaa accaaatctt
    16561 ttcagaagga aataagaaaa aggaaataaa atggtgacgc cgatgaggga aatccggcag
    16621 attgtatacc ccaataacga tgtaaagcaa ggacagtgca ccaataatga ttccatcgat
    16681 cgtacgccac tcccatgaat agatcaattg ttcccgaaat aattcgtttt tagaagcaag
    16741 aatgatcaga agcagaatag acaagaaaac caccggtgtg aaactaaaat cacttaataa
    16801 aacataaagt aaagctagaa caatcaagaa gattgtaggc aaatatgctc gtttcacacg
    16861 tgctgcgatc cctctgccca taatgattaa aagaaatccc aatagtatac taggaaattg
    16921 gataataaaa tgaaatttca atgggttcaa actatgaagc cagcgaaact ctgtaaaagc
    16981 ttgcgggata gtggcagaaa gtactagcat gattccagaa aagtataata agacaaccac
    17041 gattttatgc gcaatttctg ttgctaattg tttagggata ccagaataac gctgatcaaa
    17101 agtggaaccg atatttttga agaaaaagac gattccaatc aaaaacggaa tgatgtagta
    17161 gaacaggcga tagagcaaga tccacacaac gactatttct cttggcacac caatagcgga
    17221 caacccgata atcatcatta catcgaaact cccaatttct cctggaatca tagacacgat
    17281 tcctatcact gaagcagcaa tgaataatgg aattgtttgc cacagatcaa tccggatttc
    17341 cattaaataa ccaacagaaa ggaaactaaa caggacaccg gtccattcca acaatgaaac
    17401 tagcaatagc tgtccttgag ttttaagtga ggtaccacca aggaatcctt tctttttgaa
    17461 agtagtaaat aaaaagacga caggaaaata tagaccgccg ccgatcaacc atatccaata
    17521 ttgcttcaaa aaaggagcaa ctggcgtgaa gactacaagt aaaaaagaaa gcagactgta
    17581 aatagaaagt ccagccatca aaaacaagaa aactttcgat aatgcttgga tcacgtttct
    17641 gctctctttc ttttgtccat atagttcaga gcgaagcccc acactaacaa acccgccgaa
    17701 accggcaata ttgttgatcg tattgatcag ccagcttgtc tcaaacaggt aacgaggatt
    17761 ctgcttttgt tcaagcatcc gattcaaaat aatatcataa ccaaccatag gtaacacaga
    17821 gataagacca atcaatagca ttagtccgct tttccataca ggtatagtgg caaacgtttc
    17881 tcctaattgc tggatagata gagttttacc gatggacatc aattcaccga caataatgac
    17941 aatgacagaa atcaaaaaga ttgttttgaa cagtcctagg tggtttttca gccattgtat
    18001 ggtatttttt aacaaataaa tcaccttcta ttcctaatag ttatgtttca gaaagaaatt
    18061 gaagaacttc tcgattgaag cgttcaggat cttttctagc taattcatgt ccttgttctt
    18121 tcacaagcac aaaggaagct tttggtatag ttttagctat atacaaagaa tgttttagct
    18181 tgattacatc tttttttccc acgatgatca aagtggggga gttgattttt tttaaatcat
    18241 tttctgtaag cccgatgtca tgcagcaaaa gtttgataac taaaagattt ttgcgaagac
    18301 ttgggcgaaa taaagagagt aaccataccc atgcataatg aatattactg atgactctgg
    18361 cagaaaaacg aacgccttta acaagcgtgt ttccagaatt taaaatcaat cgatgaactt
    18421 ttttagggaa gctgctggca aataccagtg ctagatttgc tccatcacta aatccaagaa
    18481 aatctgcctg atcgattttt tccagcaaca tgatcgtatt cagatcctcg gccattaact
    18541 gaaaattcaa catagatgct tcgtttgtcg aacgaccatg tcctcggcta tctactagat
    18601 acacggtata gtagcgttcg agtacaggga cctgttctga aaaaaagcgg ccgctgccgt
    18661 cattgccatg cagtaaaaag agagggaagc cttgaccgct cttttcatag taaatttcgc
    18721 tcccatctgg catttttgca tatttctttt cttttttcac ataatcacct actgtgtaaa
    18781 gtataacgat tatatcagtc attgggcaat tgtttttact gaaaaacaac gatcattttc
    18841 gtaagatgtc aaaaaataca ggaaaattca ttttttctta aggcgtacac agaaatcaag
    18901 gaagaaatag ccaagaagat aaagaaatag taagataaaa aaagatgtca aaataactag
    18961 gtgatgaaat gaagcgaaaa cgattatcta ttatccgtat tcttttttac atgatcattc
    19021 tgacggttat tggtgcggtg ttgtttttat gaggaagaac ttatcgttcg gtaaaacgag
    19081 tggaaagcta tcaaatagaa ataacaacag ctgcaaaaaa ttatcatatg gaaaactacg
    19141 agaatttgat caaggcgata atattgaccg aatcaaaagg aaaagggaca gatctcatgc
    19201 agagctcgga aagtctgcat ggagaagctg agatcattga taatccagct gacagtattg
    19261 atcaaggtgt caaatatttg gcggaaatga tagtagaagc aaagaaacaa ggatgcgatt
    19321 tatggacagc tgtccaagca tataattttg ggaaagatta tattgcctat gtaaaaaatc
    19381 atggcggaga aaacacagta gaattagcag aagcgtattc taaagatgtg ctgagcccac
    19441 ttttaggaaa tgaggaaggg aaacaatacc gatattggcg gatccagtcc ttgctttaca
    19501 atggcggcta tctctatcat aatggaggta acatgtttta tcctgatatt gtcaaaatga
    19561 atgaaaaaat aatagagacc tatgaaaaag tctttaagta aaatagcagg aaatgttcaa
    19621 tcatgaataa aattaaatga aagaaggagt gcgcaaatag tggaaaaaag gcaaaaaatg
    19681 gaaaatcaag aagtggggta cacaaccaaa gactggatgt tacggtttgt gaagggaatg
    19741 tttatcggtt caggatttat cttgccagga gtcagcggtg gtgcattagc agctgtcttt
    19801 ggcatgtatg agcggctgat ttctttttta gcccacctta caaaaaattt caaagaaaat
    19861 gttttgtttt ttctgcctgt tggtctaggc ggagtgacag gcatctttct actttctttt
    19921 ttagtcagtt ttttattagg tgcgtatgaa acaacgatat tatggttttt tgtcggatgt
    19981 atcgctggaa ctgttcctgc gttatggaaa gaagcaggga aaaaaggaag agatacttct
    20041 gatgtgatca tcatggttgt tacttttgtt ctggcttatt tgtttttatt atgcggcgct
    20101 caattatttg acgggcaagt cgatcagaat tttggaacat ggctgattgc cggcggattg
    20161 attggtttgg gtatgatcgt cccaggattg agcccttcta attttttggt gtatatggga
    20221 ttgtataaag cgatggctga cggatttaaa gaagtacgac ttgaagtgat tgtgccgatc
    20281 ggaattggtg ggattctttg tgttcttgga ttgtcaaaaa tcatggatta cattttctca
    20341 aaggcatata gcaagctatt ccatttcatt ttaggtgtag tttttgcttc aacgattatg
    20401 atcattccta ccgattacgc gggattggga gttgctgggg tactagcttg tcctgttctt
    20461 tttatagccg gtacagcact aggttggtgg atgagccgtt tggaggaaca atataagtaa
    20521 agatagattg ataataaaaa cagcacacgg gtgattcaaa caaaaaggtt ggcatctttt
    20581 ttgtaaaatc attcgtgtgt ttttctataa attttataaa aacaagttgt ttttaatctt
    20641 ggaacacgct agacttaaac acgtgattat ttttgaaagt tggcggaaaa tggagaaaaa
    20701 gaaaatgaat ggacttacac agcaagaggt agttcagaaa atggcttctg gccagcaaaa
    20761 tgactaccag gaagatgcat caaaaagtac aaaacaaata ttcagcgata atatattgac
    20821 gttattcaat tttctgaact ttggtattgg gatttgtctg ttatttgtag gtgcgtattc
    20881 caacatggcg tatttagcaa ttattgtcgt caatatcgtt attggaattt atcaagaaat
    20941 acatgcaaga aatcttgtac ggaaattatc gattgtttcc caatcagaag tactagtgat
    21001 ccgggacggt aaagaacaat cgatttctac taaagagctg gtattaggag atttggtaaa
    21061 aatcggagca ggagaacaga taccagccga tttacaggtt atatctggac gggcagaagc
    21121 aaatgaagct cttttgacag gcgaatctga tttgattgtc aaagaaactg gagctgaatt
    21181 gctttctgga agctttttga caagcggttc tgtcatggct gaagttatcc gagtaggtgc
    21241 agataattat gctgtccgct tgactagcga ggcaaagact cacaaagcta ttcgttctga
    21301 acttgtagat tcgattcgca aagtatccaa attcactagt ttcgtgatta ttcctttggg
    21361 gatcatacta tttttggaag cactgttcat ccgcgatgct tctatcaaaa tttctgttat
    21421 tgcatctgca gcagctttgt taggcatgct tccaaagggt ttggtattgc taataagtat
    21481 tgcattaacg acaggggtaa ccaaactggc aaaaaaacga atccttgttc aagacatgta
    21541 ttcaattgaa acgctggccc atgtcgatac attatgcttg gataaaacag ggaccattac
    21601 tgaagggaaa atgagtatcc agcgggtaga agcactacat ccgctgtacg agaaagccat
    21661 cccagaaatt atggggacgt atctggcaga aagcagtgat aacaacatca ctatgcgggc
    21721 tatgagagat tattttgagc tttctaatcg gtatgatgtg acaaacaaag tcgcattttc
    21781 ttctgatcgc aaatggggcg cgatggaatt tccagaactg ggagtcgtgt acgtaggagc
    21841 gcctgaacgt ttggtggaag aagatcggct tccggacagt ctaaaaacag cccaagcgaa
    21901 tggctatcgc gtacttatgt tggggatcgc tccaaatcag caattgaacg aagaaaaacc
    21961 agcatttgtt gagccggttg ctctgtttga aatcgatgat ccaatccgaa aaaacgctca
    22021 agaaacacta gcttatcttc atgaggaagg tgtggatctg aaagtgattt ctggagacaa
    22081 tccttttact gtctccaata tcgctagacg tgcaggatta ccgaattatg atgcgtatgt
    22141 cgatctttct caaattactg aagaaatgga agtgcgagaa gctgctcatc gctatacggt
    22201 ttttggacga gtgagtccgc agcaaaagaa attgctggta aatgaattga aagaaagcgg
    22261 cagaacggtt gcaatgacag gcgacggtgt gaatgatgtt ttggcgttaa gagaagcaga
    22321 ttgcagcatt gctatggcag aaggtgatgg agcaacacgt cagattgcga atctggtatt
    22381 gttggactct gattttacta cattgccaga agtcctgttt gaaggacgcc gagtggtcaa
    22441 caatgtgacg aaagtctcag gcatcttttt tatcaaaacg atttattcat ttattttatc
    22501 gattatatgt gccgttacag caattggatt tccgtttatc cctatccaaa tcacgctgat
    22561 tgatttagcg attgaagggt atccttcctt ctttttatct tttgaacaag ataaaagaaa
    22621 aatcacttac cgttatttgc ctacagcact tattaatgct ttaccaaatg ccttgcttgt
    22681 agtagtgaat atcattgcgg tgtatctact tggaaaaaca ttcgcatggg gaaatgctga
    22741 aactactact ttgatgtatt acttgctgat tgggatcagt tgcatggcag ttgtaaaagc
    22801 ttgttatccc ttcaacccat tgcgcatctt cctagcagta acgacgatcg tagggatata
    22861 tgtagctgca atgctgttcc atggaatttt ggaagtaaac ttagggttgg gagagagcgt
    22921 aggatacttc tttgtattca tgctcgtaaa tattgttctt cgagtattgt actggaaggc
    22981 tgatattcaa aatcagttac tgaaaagagt agcaaattga tgcttaatga gatagaaatg
    23041 tgttatactt gaaaaagcaa tgaaatatga tacaatcaaa catgtataat tgtgtccttt
    23101 aaaatcgcac tgatttcagt tagtgcgatt ttttaccggt tattctcctg aaatatcttc
    23161 tgttaaaccc aaaagatatc aatagagcag ggggtgaaaa aatggctcaa cggattcctc
    23221 aagaggttat cgaaacagta cgcagtcaaa cgaatatcgt tgaggtgatt ggacaatatg
    23281 tccagttgaa aaagtctggt aaaaattact tggggctgtg tccttttcat gaagaacgta
    23341 caccgtcttt ttctgttgca gaagacaagc agatttttca ttgctttggt tgtggtaaag
    23401 gcggaaacgt gtttactttt cttcaagaac tagaaggtct aagttttcca gaagcagtgg
    23461 taaaagtggc agacttcgaa cagataccgt tagaagatca atggcgtcag cgtactatag
    23521 ctgtccaaaa tcctgaatct gctacgggga aactgattgc tgctcatgaa aaagcagcgg
    23581 aaatctatca tcacatgcta ttgcatacaa aagctggaca gccagcttta gaatatttgc
    23641 aaagtcgtgg gttgtcttta gaattaattg aagaattcaa cataggtttt gcacctaatg
    23701 agcgttcttt tcttcagcaa gtattcaaga atgaatcaat ttcaaatgaa ttgttagaac
    23761 gctctggatt gtttgtcacg catgatgatg gccgtatgtc tgatcgtttt tatcaaagag
    23821 tgatgtttcc acttcgtaat tctcaaggcc agacgatcgg tttttcagga cgctggcttg
    23881 cacctgaaaa agggcaggaa aaagatcagc ccaaatactt gaatagtcca gaaacagaac
    23941 tgttcaataa aagacaagtt ttatttaatc ttgataaagc aagaagcgat atccggaaaa
    24001 acggagaaat tttgttgttc gaagggttta tggatgtgat tgctgcatgg caggctggta
    24061 tcaaaactgg attagcttct atggggacaa gtctaacagc tcaacagatc caacaaatgg
    24121 aaaagctgac gaaagaattg gtcttttgct atgacggaga caacgcaggt tttgaagcaa
    24181 ccaatcgagg gattgaattg cttcggcaaa acagtcgatt agcactttct gtcgtagtcg
    24241 ttccagaaaa gcttgatcct gatgaatatc tccgtaagta tggagaagca tctttccaag
    24301 aattagtggc tcatgggcgc gaaacagtct ttacttttaa atcacgttat ttaaaacaag
    24361 ggaaaaattt agataatgaa aaagacaaga tcgaatacct cgaagaatta ctagttgaac
    24421 ttagccgagt tgtttcacca atcgaacaag atatgtatct atctcaactg tcaacagagt
    24481 ttcagatcgg cagagagacg atacaaaaac aactgcgcga tcttcgaagg acaaatcagc
    24541 aaaatcgtca agaacctcag gaaagtcaac acactcaggt tacgagacaa gaaactgcac
    24601 ggaaaaagag acctttgacg caagtagaaa aggcagagca gattctatta tatcgtgcat
    24661 ttaaagaagt ttctgtccgt aatattttaa aagaacgaga atttcagttt attcatgatg
    24721 catatgcaga agtttatttt ttattcgatg catatgtctc acaacattat gaattcaacc
    24781 ttgcagagtt tttagacttt ttgcaagatg aaaatttaag gcggttggtg gtggaaatcg
    24841 aatatttacc ggtggcagaa gaaagttcgc cacgagaaat ccaagacttg ctagatgtga
    24901 tcagcaaatc tggcttagct gatgaaataa cattaaaaaa acaaatgcag caagaagcca
    24961 gacgaactgg aaacaaacag cttgagcttg aattgacgat tgaaatcatc aatttaacga
    25021 aacagttaaa acaagccaaa tagctactca aggggggcct tcttttatgg caaatggaac
    25081 agataaaaaa acgtatgaag cagcagtagc agctttcatc aaagaaaaca aacccaaacg
    25141 acaagttgta tatgatgatt tatccaatca gcttgctaca ccattcactt tgaatgcaga
    25201 tgaaatggac aaattgatcc aaaagattga agacgcaggt atcagtgtgg tggatgaaaa
    25261 tggtgatcca tcaattcaca gcttgaagag tgctgagaaa aaagctgaac aagcaaaaac
    25321 agaagatctt tctgcgccaa ccggtgtaaa aatcaatgac ccggttcgta tgtatctgaa
    25381 agaaattggc cgtgtctccc ttttaactgc ggaagaagaa gtagcgttag cattgaaaat
    25441 cgaagaaggc gaccaagaag cgaaacagcg tctggcagaa gcaaaccttc gtttagtagt
    25501 aagtatcgct aaacgttatg taggacgagg catgcagttc cttgacttga tccaagaagg
    25561 aaacatggga ctgatgaagg cagttgaaaa atttgactac cgcaaaggat ttaagttttc
    25621 aacctatgct acatggtgga ttcgtcaagc catcactcga gcaatcgctg accaagcacg
    25681 tacgatccgt attccagttc atatggttga aacaattaat aaattgatac gtatccaacg
    25741 tcaattgctg caagaccttg gaagagaacc tacgccagaa gaaatcggtg cggaaatgga
    25801 tcttccaaca gaaaaagtcc gagaaatctt gaaaatcgcg caagaacctg tttcccttga
    25861 aacgccaatc ggtgaagaag atgactctca cttaggtgat ttcatagaag accaggaagc
    25921 aacaagtcca gcagaacacg cagcttatga gttactaaaa gaacaattgg aagatgtact
    25981 agatacattg actgatcggg aagagaatgt ccttcgctta cgttttggtt tagatgatgg
    26041 ccggacgaga acattggaag aagtagggaa agtatttggt gttactcggg aacgtattcg
    26101 tcagatcgag gctaaagcat taagaaaatt gcgccatcct tctcgttcaa aacaattaaa
    26161 agatttctta gaataagcgt ggactattga ccagaagaga aatcagtaaa actgtttggt
    26221 ttattttaaa agaaaaaaag cttgagacta cgcagtctca agcttttttt tctataggaa
    26281 ggaaattcat tcattatttt taagtaaatc ctaaaaataa gctattggcg tgacgtatag
    26341 aatatgatag attaaatggt agcgtaaacc tagtaaagga gccgatcgct aagtgatgaa
    26401 aaaatgtcca aattgcggat cgaaaaaaat ggagcagaat actatctgtc cagactgcgg
    26461 tcatcaaata actgcagaag atcagcaaat aaaagaatca attgaagaaa caaatacaga
    26521 tgcagctatg caggataaat caactgaaga tgcagtcttt cctgatacag aattaaacga
    26581 tccaatcgaa tggtcggaat tgaaagattt acctctagaa tctgtaatgg aattattcga
    26641 aaaagcagaa ccagaagacg aagaaccacc tgctcacgat caagtaacta atatagagaa
    26701 aaatgaacag aagaaagcaa ctgttcatga gacttcggaa gaatcaggaa agaatcaaga
    26761 agaaacgctt gaatcaaaac aaaaaagaag agtagctgaa ctgaaagaaa tcgtcgataa
    26821 tgaggaagaa aattcgatac tatccgctta tatcaaagca catcgtgaag atacaaaaga
    26881 agagcacgcg aaagagctgc tcaaaatgat cagtgaaaaa attgcacagg aaaacaaagt
    26941 agagccagaa aaggaacaag aaactgaaaa agactctgat agagaaaacg ccacaggtaa
    27001 agaaacagta aaaataaaag acgtaaaaac ggatatcaca gaaaaaactg aagtatttac
    27061 tgaaaaacaa ttagaaaagg aaaaaacgaa taaactgccg gaagcagaga aaaaagaaat
    27121 actcgaaaac acagacaaaa agtcaacaga gcccgatgaa ataaatagtg aatccgatgc
    27181 tgaaaatcaa tctgtaagca aagagggtac tgatcttgaa gcaaaaatag aaaaagaaga
    27241 gaaccagcct aagctgtttg aagcagaagc gaaatcaata acaatcgtgc cagatactga
    27301 aaaaacacat caagaatcaa acttagaaaa aacagatcca gataaagcgc aaaagaaaaa
    27361 atcaaaaaaa gtaccttatc tcgttttagc agcagtactt ctactcggtg gaggaagctg
    27421 ggcttattat gaccatcatc aaaaagtaga agccgaagta gcagcagaag caaaaagaca
    27481 gcaacaaatg gaagaacttc atgagaaact tgctgccttt tatacagatg atcaccatca
    27541 atttattcgt gcagatatga ttcatcaaga tttatcaaaa ctaaaaaatg atttatccag
    27601 tcttaagaat gaaaaaggat attcagagtt agaaacaact taccaagata tccaatctaa
    27661 gatccgagat atccaaaaag tgaatgagtg gttcatagca cctgccatcg tcgatgatca
    27721 tctagcagat gacatcaagt tgaaagcaga taaagagatc caagcaatcg aaacggataa
    27781 cacagatttt ggaaaattga ttcaacaagc acaaacagaa gctaaaaatc aatatgctga
    27841 attgcaaaca gctaaagaaa aaacagctat agtctttaaa gacggaaaag tagtggattc
    27901 agcaacacgc gaccaataca agacggcaaa agaagcagta gaaaaagtga aaaatacaga
    27961 tctatctgct cagttgaatg aacaattgaa acaagtagat aagatgctca ctgataaaga
    28021 gaaaaaagaa gaagaggaaa agaaaaaagc agaagaagcg aaaaaagcag ctgaagaaca
    28081 agcaaaacaa gccgctcaag cagcagctgc agctcaagcc gctcaacaag ctgcggtcgc
    28141 acaagcagca cagcaagaag cggcatcctc gaccccttcc tcttcaaact cagcgaatca
    28201 gccaatcaaa tctgccagag caagtgatat tgccgatgca tctaatccag catggacgtg
    28261 ggcaccaggt gtccaaagca aagtgattgc tacatgtatc caacgtggat atatcgttga
    28321 aggaggttac agattagaaa aagccagaat cgaaaatggg gaaggctatt ataatctata
    28381 tgccacttca acaaaatctg cattgatgaa aggcattgga gaaagtgctt tgccatttta
    28441 catcgtaacc atcaactgta aaactggatg gttcggagga aatgggagca attaatttta
    28501 ggcaaatgaa agaggctgtg agcctgccgt ttaacaccgt ttattcgaaa aaggggagta
    28561 tgacacaact gttgtcatac tccttttttc acctttccaa accaaggctc agctattcaa
    28621 gtagataaca ttatgttatg atagcaaaga aatgtattaa gaaaaccttt cactatagag
    28681 ggagaaaaaa atgaacgatt tattagcaac tatatttaca ggtattatta ttgatgaaaa
    28741 tgaaaaaaac tactttgtcc aaaaaaacgg acaaaccttt ggcttaagca aatcagaagg
    28801 tgaacacaaa atcggtgaag cagttgaagg attcggttac caaaatcaaa aacatgaaaa
    28861 tcggatcact acacaaattc ctaaaagccg tatcggtcat tacgcttttg gaatcgttac
    28921 tgctacacga aaagatttag gtgcgtttgt cgatatcggt cttccagata aagactttgt
    28981 cgtatctctt gatgaattgc cgacaatgac agagctatgg cctaaaaaag gggatcgctt
    29041 gatgatttcc cttagagttg atgcaaaaga ccgtatttgg ggcagtttag cagatgaaaa
    29101 aatattcaaa tctttaagca aatatggaac agaagaaatg aaaaacaaag atgtgatagg
    29161 aacagcatac cgcttgaaat taacaggtac gtacgtttta acggaagatt tctatcttgg
    29221 gtttatccat ccttctgaac gatataatga acctcgtcta ggcgagcaga taaaaggtcg
    29281 agtgattggt gtccgaccag acggtgtact gaatctttca ttgaagccaa gagcatatga
    29341 agctatatca gatgatgcac aaatgatttt aaccatttta gaacgttctg cagatcagca
    29401 aatcaacttt acagataaat cggatccaga agaaatcatg aaagcttttg gtatcagcaa
    29461 aggagcattt aagcgcgcat taggtaatct tttgaaacaa ggattgatta cacaagaaaa
    29521 cggtgtgaca aaactagtca aaaaatctaa ttgagaatcc cttgcatgtt tttcttaact
    29581 agcttataat aattttaatt aacatagtgt tatatctttt tttatttgta attattataa
    29641 attgttgggg ttgagtaaat ggtcatgaat gctatttcgg cgatgaaaaa aacaaaacag
    29701 cagctacatg aagcggggtt taagctgaca ccgcaaagag aagctactct gcttgtgctt
    29761 ttggaaaatg agaaagagca tttatctgca gaagaaatct tctttttagt gaaaaaaaag
    29821 agtccggaaa ttggacttgc tactgtttat cgaacccttg aaatcttgac agaattgaaa
    29881 attgtcgata aagtaagttt taatgatgga ttagcccgtt atgatttgag aaaagaaggc
    29941 gccaaacatt tccatcatca tttactatgc ttgaactgcg gcacgatcga ggaagtagaa
    30001 gaggatcttt tacttgaagt ggagcaagta gtagaagaac gttatcattt tttagtaaaa
    30061 gatcatcggc taacgttcta tggaatctgt caggaatgct atgaaaaaga aaaa
//
LOCUS       DBBGRF010000034        28602 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000034 DBBGRF010000000
VERSION     DBBGRF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.034"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            236..1876
                     /locus_tag="ACIZD4_001729"
     CDS             236..1876
                     /locus_tag="ACIZD4_001729"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HGC5990666.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2030..3352
                     /locus_tag="ACIZD4_001730"
     CDS             2030..3352
                     /locus_tag="ACIZD4_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HGC5990667.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3414..3845)
                     /locus_tag="ACIZD4_001731"
     CDS             complement(3414..3845)
                     /locus_tag="ACIZD4_001731"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5990668.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3909..4745)
                     /locus_tag="ACIZD4_001732"
     CDS             complement(3909..4745)
                     /locus_tag="ACIZD4_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGC5990669.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4935..5237)
                     /locus_tag="ACIZD4_001733"
     CDS             complement(4935..5237)
                     /locus_tag="ACIZD4_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGC5990670.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5263..5694)
                     /gene="ruvX"
                     /locus_tag="ACIZD4_001734"
     CDS             complement(5263..5694)
                     /gene="ruvX"
                     /locus_tag="ACIZD4_001734"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGC5990671.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5691..5957)
                     /locus_tag="ACIZD4_001735"
     CDS             complement(5691..5957)
                     /locus_tag="ACIZD4_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGC5990672.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6211..6936)
                     /locus_tag="ACIZD4_001736"
     CDS             complement(6211..6936)
                     /locus_tag="ACIZD4_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HGC5990673.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7302..7372)
                     /locus_tag="ACIZD4_001737"
     tRNA            complement(7302..7372)
                     /locus_tag="ACIZD4_001737"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7338..7340),aa:Gly,seq:ccc)
     gene            7489..8241
                     /locus_tag="ACIZD4_001738"
     CDS             7489..8241
                     /locus_tag="ACIZD4_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGC5990674.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8257..8736
                     /locus_tag="ACIZD4_001739"
     CDS             8257..8736
                     /locus_tag="ACIZD4_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGC5990675.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8987..10567)
                     /locus_tag="ACIZD4_001740"
     CDS             complement(8987..10567)
                     /locus_tag="ACIZD4_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HGC5990676.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10560..11303)
                     /locus_tag="ACIZD4_001741"
     CDS             complement(10560..11303)
                     /locus_tag="ACIZD4_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990677.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11479..12255)
                     /locus_tag="ACIZD4_001742"
     CDS             complement(11479..12255)
                     /locus_tag="ACIZD4_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGC5990678.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12503..13339)
                     /locus_tag="ACIZD4_001743"
     CDS             complement(12503..13339)
                     /locus_tag="ACIZD4_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGC5990679.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13350..14279)
                     /locus_tag="ACIZD4_001744"
     CDS             complement(13350..14279)
                     /locus_tag="ACIZD4_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGC5990680.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14471..14824
                     /locus_tag="ACIZD4_001745"
     CDS             14471..14824
                     /locus_tag="ACIZD4_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGC5990681.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14898..15554)
                     /locus_tag="ACIZD4_001746"
     CDS             complement(14898..15554)
                     /locus_tag="ACIZD4_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGC5990682.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15780..17714
                     /locus_tag="ACIZD4_001747"
     CDS             15780..17714
                     /locus_tag="ACIZD4_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGC5990683.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17800..19023)
                     /locus_tag="ACIZD4_001748"
     CDS             complement(17800..19023)
                     /locus_tag="ACIZD4_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC5990684.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19017..20888)
                     /locus_tag="ACIZD4_001749"
     CDS             complement(19017..20888)
                     /locus_tag="ACIZD4_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HGC5990685.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(20909..22027)
                     /locus_tag="ACIZD4_001750"
     CDS             complement(20909..22027)
                     /locus_tag="ACIZD4_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC5990686.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22110..22943)
                     /locus_tag="ACIZD4_001751"
     CDS             complement(22110..22943)
                     /locus_tag="ACIZD4_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990687.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22936..23853)
                     /locus_tag="ACIZD4_001752"
     CDS             complement(22936..23853)
                     /locus_tag="ACIZD4_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990688.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24080..25204)
                     /locus_tag="ACIZD4_001753"
     CDS             complement(24080..25204)
                     /locus_tag="ACIZD4_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC5990689.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25387..26295
                     /locus_tag="ACIZD4_001754"
     CDS             25387..26295
                     /locus_tag="ACIZD4_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5990690.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            26436..28049
                     /locus_tag="ACIZD4_001755"
     CDS             26436..28049
                     /locus_tag="ACIZD4_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC5990691.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         8893 a         5622 c         4867 g         9220 t
ORIGIN      
        1 tctatttatc tatctaacat atcctttatt cttctacttt tctttcttta gcatataaga
       61 gatacgcata gtaatcaagc aaggattgtt gatataaaaa gaacaaatac cgctattttg
      121 atttcttttg actctattac tcatataaat aaaatttatt atacctgctc tttttgacta
      181 tatcctcatc tgactcctat acttcgtttg tattaaaact taggaggaat cattcatgct
      241 tacagggcta aacttattaa ataatccttt tctaaataaa ggaacagctt ttacaaaaga
      301 agaacgggca aaatacggaa tcactggtat gcttccaagt actgtccaaa cattggaaca
      361 acaatctgtc caagcttacg gtcaatactt aagcaaacag accgatttgg aaaaacgtat
      421 cttcttaatg aatctattca atacgaaccg gacattgttt tataaattga tgggcgaaca
      481 tttagttgaa ttcatgcctg tcgtttatga tcctgtcgtt gcggattcaa tcgaacaata
      541 caacgaaatt ttcttgaaac cacaagatgc tgtatttctt tcaatcgacg aaccagaaaa
      601 tatcaaagca agtttgaaaa acgcagcaga tggacgcgac attcgtttga tcgttgtgac
      661 agatgcagaa ggaatcttag gtatgggtga ctggggtgtg aacggtgttg acatcgctat
      721 cggtaaattg atggtctaca ctgccgcggc tggtatcaat cctgcacaag tcttgcctgt
      781 atcaatcgac gctggtacta ataacgaaga attattgaat aatccattat acttagggaa
      841 tcgtcatgct cgtgtagaag gcgaaactta ctacgaattc attgatcaat tcgttcaatc
      901 agctactgaa ttattcccag aattgttatt acattgggaa gattttggac gaggaaatgc
      961 tgcaacgatc ttagaaaaat acgaagataa aatcactact ttcaatgatg atatccaagg
     1021 cacaggaatc gttgtactag ctggtgtatt aggtggattg aatatatcag gtgagcaatt
     1081 gaaagatcaa acgatcttga catttggtgc tggtactgct ggtgtaggta tcgcaaacat
     1141 ccttttagat gaaatgatcc gtcaaggtgt acctgaagaa gaagcacgcc aacatttcta
     1201 tcaagtagat aaacagggtt tattgtttga agatacaaaa ggattgactc ctggtcaaat
     1261 cccattcgct cgtaaacgct cagaattcac taatgctgat gaattgacaa acttagaagc
     1321 agttgtaaaa gcaatccatc caacgatcat gatcggtact tctacccaac ctggagcatt
     1381 cactgaagaa atcgtgaaag aaatggcggc tcatacccca cgtccaatca tcatgccttt
     1441 gtctaatcca acaaaattgg cagaagcaaa agcaaaagat ttgattgaat ggacggacgg
     1501 aaaagcttta gttggaacag gtatccctgc tgctgatgtg gaatataacg gtgtaactta
     1561 ccaaatcggt caagcaaata atgcgttgat gtacccaggt ttagggcttg gtttgattgc
     1621 ttcaacagct acacgagtaa atgctgaaat catttctcaa gctagtcgag cattaggcgg
     1681 aatcgttgat gtaacaaaac caggagcagc tatcttgcct ccagtagcaa aaatcactga
     1741 attctctcaa acgattgctg aaactgtcgc aaaatcagtt gttgcacaaa aattgaatcg
     1801 tgaagaaatc acggatatca aagaagctgt tgaatctgct aaatgggttc ctgaatataa
     1861 atctttagaa gattaagatt gttatagtaa aagaacatac agaaactttg tatgacgtct
     1921 aaaaagaaaa aagcgactgc ggcaaaacag cagccagcca actactgctc ttttgccgct
     1981 tctctttggc ttttttcata cgatacagaa taagaaagga tctgtaaaaa tggcacaaaa
     2041 aacaacaacc gcaactgcag ttgaggaaaa gaaaaaagaa gggttttggt caacaaaaat
     2101 taccggcgta agtttgcccc tttatttgat catggtcctt gtcctgatca ttgcaatggc
     2161 tttaggaaaa ttaccgacga atatgattgg cccaatcgct gttttggtca ttttcggtaa
     2221 tttatttcat tttatcggaa caaaaatccc tatagtcaaa agttatttag gtggtggctc
     2281 cgtttttgcg atctttgcct ctgccgcgat tgctacattt gggatcttac ctgagtatgt
     2341 agtaaaatcc acagaaaact ttgtcagcaa tatgggcttt ttagactttt atattgctgc
     2401 cttgattact ggtagcatcc ttggtatgaa ccgtaatcta ttgatgaaag cttctgttcg
     2461 ttttattccc gttgcactta tttcaatggt cgtctccttt tttgccgtag gactcgtagg
     2521 tatgcttatc ggaaatggtt ttgcaaattc cgttttatat atctcattgc ccgcaatggc
     2581 tggtggtgtt ggagccggag ctgtaccttt atcaacgatt tatgcaaatg ttttaggtac
     2641 ggacgcttct tctatcattt cccgcctgat tcctgcgaca gcaatgacaa atgtcctagc
     2701 tatcattggt gcagcgttag ttgctcgtgc gggacaatca atgccaaaat tcaacggtaa
     2761 tggtaaatta atggaaaaag gcgaccttgg cgatggaaaa cctagaaatg taaaaccttc
     2821 cattccacaa ttaggtgtcg gtttgatggt atcattgact ttcttcatct taggacaaat
     2881 ctgtaactat tttgttccta aagtccatgc ttacgcattc atgatcatta tcgttgttat
     2941 ctgtaaaatc gcaaacctat taccagaata ttacgaagat gcagctatca tgttcaacaa
     3001 cttgattgtc aaaaacttga cagcagctgt tcttgccggt atcggtattg cgttattgaa
     3061 tctaaatgta ttggcttctg ctttgacatg gcaatttgtt gtcttatgtt tgacaagtgt
     3121 tatcgcgatt tcagtagttt caggatttgt cggtcgtttg tttggtttat atccaatcga
     3181 atcaactatt actgctggct tatgcaacaa ctcgatgggt ggtacaggaa atgtagctgt
     3241 cttatctgca gctaatcgga tggaacttat tgcttttgct caaatgggca atcggcttgg
     3301 tggtgccatc gttttgatca tctcaggttt cttgatgcaa ttactttctt agtcaaaaaa
     3361 aatacctgat catcaagtat cggcttgatg accaggtatt ttttgataaa aatttacagg
     3421 attttcaaaa atcttttttg cattttatcg gaatgataac cgatgcgttc ataaaatcgg
     3481 tgtgcttcta ctctgtattc tgcagaatta agtcttattg ctgatattcc tcgtcttttc
     3541 gcttcttcta cgccagtcat caaggccttt ccgattcctc ttttttcagc atgtttagac
     3601 acagcaagtg ccataatatt gaacatcgga tcgctgaaaa tcgattcata ggactccgct
     3661 tgtacatagc cagctgcttt tttagaagta ggatcttcat agaccaagaa aaaatttttt
     3721 tctggctcct tcaacagttt cttcatttgt ctcaccgtaa cggttaatgg tacatcatat
     3781 cctaattgtt ccgcattgat ttctcgtagt gcttctgcat ctcctaaacg catttcccgc
     3841 aacatccaaa tcaccagcca atttttattt ttttaaatga atttttttat cacagtatac
     3901 tccttttttc acttaaaaaa agacttttca gtgattttga cttgcttgaa tccagatcct
     3961 tctaatgttt gcaagatgac gaaagcattg taaagattga tcaaaagaac cacgatgaca
     4021 atcgcttgaa aaataaaggt cacttttttt ggagacaaaa ccctgctaaa tcttgctccc
     4081 cacaaacctc caataacagc agcggggata acataaaaca acatagataa atcaaagcgc
     4141 ataaagctac ttgttaaagc aatcgttacc aattttgcca gttgagaaaa gaaaatcgta
     4201 gatagagaat atagtgttgc ttcttttatt ggcaatgcaa acatcagcat caacaaagaa
     4261 acattgactg gtccaccacc aatacctaaa aaactagcta aaaagcccag aaccccccca
     4321 catataaggt accaagtcca tgacgtcaaa tgaaattttg gctgatgatg cttggtgtag
     4381 aagaacgcaa aaaccaaggt caataccgtc aaaaaaattt ggatcagctg cacatgcttc
     4441 tcgttttcaa ataactgtaa aaaaacttcg aatacaatgt tgccgactac tcctccaaca
     4501 acagctccac tagataccca accgacaatc tgccaattca gtgatttccc gcttgatact
     4561 tgtcgcacag tcgaaacaat ggacatcgtg aataccgcaa ctgttgagta aaaagaaatc
     4621 cctgcaacag aatgggcgcc gataagatca agaatcggtt tgatcaacac gcctccaccc
     4681 atcccggaaa tagcgccaac tgtgttcgcc agaacgatca ccacaaaata aatcagacca
     4741 atcatcttgt atttcctttc tcttgtttat atcttttagc gattgttact cttttctttt
     4801 attatacagt aaaagaaaca aacgaggctt cgaaagcttt tctacttttt aaggaaattt
     4861 agtgctaaac gaaaaaaccg ggctctactt ttcagagagt ccagcttttc ttacacctta
     4921 tcgattcttt tgttctattc ttcttccgcc atgaatgtat tgaatacttc ttcgatcata
     4981 tcccattctg cgtctgtttc gatttgttct aactcgcctt ctgttccatc ttcgttttcg
     5041 atgtatgcat aagcttgtaa ttctacatct tcatcttctg aaacaccagc tggatataaa
     5101 agaacatagt tacgtccaaa ttcttcttgt ccgtcaactg ttagcaagat ttcgtataat
     5161 gtttcatttc cttggtcatc caccaatgtg atgtgttcgt gtccttcgtg ttcgtgggaa
     5221 tggttatgtt ctgtcataag attacctctt ttctttttat tattaaaata attgcttacc
     5281 tgagccgtct aaataatttt gtaaaatcat cacagctgct aatttatcga tgactttttt
     5341 tcgtttcgct cttgaagtat ttgcctgctc tactagcata cgttctgcct gaacagtggt
     5401 tagtcgttca tcttgataat caaccggcaa ggagaatagt tctttgatct tctctccata
     5461 tgacatggaa gcttctgccc ttggtccgat ggaattgttc atattcttag gtaatccaac
     5521 tacaaaacgg tctacttcgt actgcgccac taattccttc aaccgatcaa aaccaaactc
     5581 ttcttctgcc tcattgattc gaatgatttc tactccttga gctgtccagc caaagggatc
     5641 gctcacagca acgcctactg tcttagaacc gacatccaag cccattactc tcataaattc
     5701 actccatgat ttgagaggta gtctttgaca attacttcca tgatttcatc gcgttcgtga
     5761 cggcgaatca aatttcgtgc atcacgataa cgaggaatgt aggccgggtc tccagaaagc
     5821 aagtagccga caatctgatt gattggattg tagccttttt cttccaaagc ccgataaaca
     5881 atcgctaatg tttcgctcac ttcttttttg cgactatcgt caaaaccaaa acgtacggtt
     5941 tcatctgtaa aacccatgat tctacacctc tttcccgcaa ggtaattcca gcttaccttc
     6001 tacaccctta ttttactcga agaaagggaa aactacaaac aaatattcca aacttctgaa
     6061 taaattaaga aacacgattt gtctgatttt tccttttttc tgtggctttt tcaaaagccc
     6121 tctttccata aagtatacgc tatatttctt tgaaagtatg tttttacaca attttttcat
     6181 aaagttcata aaaaattcga attgctgcta ctaatttttc gttttcgttg cttgccctgt
     6241 ctcataattg atggtgtagc catcttgaac attgtagata aagacattga attcaatttt
     6301 tttgtcttca atgctttctg cttccaactg cacacctctt gctaccagtt catttccctc
     6361 gaaatgagga gtgacacgat agcgtacatg atgatttgtt tccttgatat atgccgcaat
     6421 atcattttcg tgggcaagca tgtacggagc attcaacgaa cgtgtccctg tcattaagtt
     6481 tttaatgtta ttattttgac cagtcaactg gaaaccaatc aaatggctgc ggttgtataa
     6541 ccattgtccg tcacttaatt tcttttgttt ccaacctgtc ggatcaatat acaaaggttc
     6601 tctcttttca gtaggaaaca agtcttttcc caacatcgca ttggcttgtc ctactctgtt
     6661 caatttgtct atatttgaat agctttccca tgtccctttg gaaagactaa gatcctcttt
     6721 tgtaaactcc ggctgattcc cattgatttc tatttcttga tgttttccat catattctgg
     6781 cacatccgct acttgagaag cttgcggtgt ggaatcaaaa atggttgtaa tttgttggaa
     6841 gatatctgaa tctttttgtg tggtggaaat accgagtgcc cctgcaatca cagcagcgac
     6901 gatccccacg atcgccttgg ttgttttttt gctcatttct ttactccttt actaacagtt
     6961 ccctaaatct taacatatgt tcccctataa ataaatactg gaaagaaata gaaacagtaa
     7021 aaaaataaaa ccagttttta gacggcttaa gaatacaaaa aaagagacgg attcatcgtc
     7081 tctactcaat cacaaaacac tatttacaag gtatttatta tcattcaaaa aatttttctt
     7141 aatactcaaa actaaacggc ttctgtacga cctcttggta aacagtgttc aaaagcttgc
     7201 atctgcggta ataagtccaa ccaagtcaaa aacataagaa gcttttttgc ttgactattc
     7261 ttattacttg atgcagggca gctttttcac agcctctttt aagcgggtga cgggaatcga
     7321 acccgcgaca tcagcttggg aagctgggat tttaccacta aactacaccc gcgatacaaa
     7381 aacagtatac gcctctttca ctccttcctc aagttttttt attctttacg cttccgatat
     7441 gttttgtagt aaaataaaac taatcaatca attattggag aagatgctat gacgggaaaa
     7501 gaattagatc tgttgctgga cacttgttta ctcgctggga aaatcatgat ggaaagcaat
     7561 gcggagatgt atcgggtaga agatacgatg agtcgaattg ctttagcttc tggaaatttc
     7621 cgtttggtca gctatgtcac tcaaaccggt ctctttattg gtcttgatcg tacctcgacc
     7681 atccgaatgg aacaaattac caaccgttcg attaatttag aaaaagtagt aaaagtaaat
     7741 gatctttcac gtaaatatgt tgcttcagag ctaacattag aagaacttta ctgcgaactg
     7801 caagcaatcg accgagaccg ttctttcttt cctgtctggt tgcaaatcgt tagcgcggca
     7861 gtgatcagtg gaacaattat ggtgttattt ggcggaaaga tgaccgattt acctgtgact
     7921 ttagtcattg gaggattggg atacgcagct tatctatata gtttgaaatt ttttagaatc
     7981 aaatttttat cggaattttt atcttcttta ttgattggca tagccgctat ctacagcgta
     8041 cgttttggct taggaagcaa tcaggatcta atcattatcg gatgtgtgat gcctttagtt
     8101 cctggagttc aaattacgaa cgctatccgt gatttgctag ctggacatta tgtctcagga
     8161 gtttctcgcg gaacagaagc gatgatgact gctacgatga tcggttttgc gattgctttt
     8221 attttccagc ttttttatta ggaaaggaac acaagtatgg ggacgatatt tattcagttt
     8281 tcttttagtt ttttagcgac tgcggcattt gccgttatta caaatgtacc taggcgttca
     8341 ttgatttgtt gtggtctttc tggtgctttt ggctggatga tctactggat ctgtgttcaa
     8401 ataggcggat ctgctgcttt tggttcattg cttggttctt taggagtagc attcatcagc
     8461 gatcttttct ctaaacgttt gaaaatgccc gtaacgattt tcaatattcc cgggatggtt
     8521 cctctagtcc ctggtggttt agcttatcaa gcggttcgaa atctcgttac tgaatcctat
     8581 cgagaagcgg ctcattatgc ggtccaagca attatgattg ctggagcaat cgctttaggt
     8641 cttgtattat cagaagtctt taaccataac atccgtaatt tcaaagtaaa gcgtgacgca
     8701 atcatgatga aacgaaaaaa acggcttttt aaataaacga agtgtaacaa agaaaaggtt
     8761 gtgaaagaga cgttcagcct tgagcgatga caaaatatct cacaaacatt gcgacaagta
     8821 accgcaggag caataagaag taattatgag tattaaaaaa agttttgtaa aaatagcttc
     8881 tcacattttt acataaaatt gacttaatac tgagaaactg acttttgaac accctctatc
     8941 tgtaaaaaag gggctgcgac atgatttttg tcacggcccc tcttctttat tcaaattttt
     9001 tccaaaacgt tcgttgataa taaacgatcc atagagcgga aagtattaga actaaaccga
     9061 tcacaggaat attcactaac caaaatggat aaaacaaagc caacattccg tataagacga
     9121 taagaataat actgatgatc aatgaaccca tcatagttgc gactaaaccc aaacttcctg
     9181 aacctctgtt aaataattgg ttaatattgg tccagttcag cagcagcaac cgataatctc
     9241 tagcgaaata acgtagtgac aataagtagc agccgaataa agaaccaaat agcaagctag
     9301 ggataaaaaa caaaggcagc tgaaaagaca gtccgcttaa taatgcgatc ccaccagtta
     9361 aaaaactctg caatatccat ccgaatctga acttttcttt taaatattgg ttcatagaga
     9421 ttggcaaaga acggataaac agaaaatttt cttgatccaa agaaataaga ttgctgataa
     9481 aagaagtctg attaactgtt aagaaagcca atgcgatccc taccaggaaa acaacaccga
     9541 ttaacttatt atctaaatca gttaatttta tttcgcctcc tagggcaaaa gcaagaataa
     9601 aaatgattgg agttaacaag gaagaagaaa gaacttgcat aatcaaatta ggttctttta
     9661 ctaattgagc attgtaacta aataaaagct gatgcacatt ttggttcttt ttatgggttc
     9721 tttttatttt gaactcactg tttgaatcag tcagttgctc tgtaagcttt ggtactatca
     9781 gctgttttac agcaaggaaa aatcccagag ccgtgatagc tagtattccc caacccaata
     9841 aaccttgttg agaaagtggc tgactggcag catcatagaa tggcaataat atcgaaatcg
     9901 gatgccgatc tgttaactca ttttcaatag tccccgtttg atgattcatc cacatgattc
     9961 cagcaaatgc gatcagcatc gagctgccaa gcaagatact agaaactgtt tttctatgtt
    10021 ttttaaacac tgctgttcga gccaaaccaa aaacaatcaa actagccaga caaaaaagaa
    10081 taatcaaaaa tagagaaaac aaaaggattg agataatgat agtaagcaaa atccctagat
    10141 cagctcgcca tccggttaaa ataaacatga ctagaagcgg aaaaacaaaa ggaatgatgg
    10201 tcaaagcaac taccaaaatc tttgctgaaa aaacctgttc ttgtccaaaa ggcagaggca
    10261 aaaatacttg caggtcattt ccttcaaaaa agatattata aatgactgat atactttgag
    10321 ttaaacctaa cataccaaaa agtgccacgt aataagtaaa gaaacctggc aatttaacaa
    10381 agttcatagc aaacatagca aatccgtaaa tcagtaaaaa aatcagccct gaaaaaagat
    10441 tttgagacaa aagatagata gttaatcgct ttcccttttt tcctttctct cttgctttat
    10501 tcgtgagctg tggattaaca tataaaagat taactcgaat taattctaat aattgtcgct
    10561 tatacatacg gtccatctcc tgtcgcttgc cttccagcca ttttcaaata aatcttttct
    10621 agcgtttcat caggtgagcc attcaataat tcactaactg ccccctgata aatcaattca
    10681 cctttcttca aaatagccag tttatcgcat aactgttgtg cggtatccaa tacatgtgta
    10741 gaaaaaatga ctgtttttcc ttttgcggca tgagccttca tcatttcttt caaatcaaat
    10801 gctgcttgag gatcaagtcc ttgcaaaggt tcatccaata cccaaatatc tggatctggc
    10861 agcaacgtgc cgatcaaaat cgttttttga cgcattccat gtgaaaaact tgcgattgtt
    10921 tcattttgat gactatacat atcaaaaagc gctgtcaatt ctgctaaacg cttttctttt
    10981 ttttgtgtgt ctaattcata ggcagctgaa atcaagtccc aatattctcc agccgtcaat
    11041 tgtaaaaaaa tatctgggga atcaggcaca taaccgattt tttgtttgat actcaatcga
    11101 ttttccgtca atttcattcc atctactaaa atcgttcccg atgatggttc aataatacta
    11161 actaaacttt taatcgtagt tgattttccg gcaccattat gtcctaaaaa tccaaaaatt
    11221 tccccttgtc ttatcgagag agacaagtct tttaatgctt gttttttccc gtaactttta
    11281 cttacattga tgaattcaat catttctgta ctccttttgt ttgttattac tttttattgt
    11341 acccttcgtt attggtggag taaatgtcaa aaagagtgca taacaaaaaa ggatagaaac
    11401 gactaggctg ctacttgggt tgttctcttc tacaggaaaa cactcttcta acaggtaaga
    11461 tatgagtctt tgttttcttt aaaatgattc attttctatc ttttcttgca taaaattctt
    11521 tagtttatca atacttctct ttcccatctc tagttgttct ccatttgcaa atgttactat
    11581 ttcgtttact ctgctaatag atgtaatgtt ttcagtatta atgatataag cttttaaatc
    11641 tttacataaa tactcatatt cgagtgattt tttatatttt ttaattgtgc cgtttacgag
    11701 aatctcttca tctttcaata ctaggcctat tttattttta taacctggca tgctcattag
    11761 ataaaggatt tcatcgtaat ggatatagtg atcgctatta ccataacgga cagttgtcca
    11821 cctttttttc gtagcatgtt gaacaggata gttttctttt tctttcaata agtaactttg
    11881 gatgcttttt ttattttttt cataagtgaa ttcttttatc aaataaccac taggcgtaat
    11941 ctttcgatta ataacagtta ttgctttatt cggatgagac gttagataaa caattttaca
    12001 cttttcattc ttttctctaa gcatttcgcc tagttcgata ccgctataat aggcgttcaa
    12061 atcgatgtct aggaaaaaaa tatctgagga atagatttca ttatttttaa tgaattcaac
    12121 aaattgtata acgttcaatc cctgaacgat ctcaaatttc caaggactta ataaaattct
    12181 ggattcttcc aaaatttcta ctagcatttt ttcaaaaacc aaactatcat ccaaaataaa
    12241 tatacgcgtt accataaaaa gtacctccac tcgatatttt actatcaaaa tcatttcata
    12301 caacttttca acatacatgt taggaataaa ttgtaattct cttcacaatc ttttccaaca
    12361 cctttgaaac cgatatcaaa tactttcagg atgctgcttc taaaataaat atcaaacaaa
    12421 tgaatacatc atgcaaaaaa agccagacaa ccgacgtcct tgcgtgtcag ctgtctgagc
    12481 tatgtttatt tattttgttc ttttaaaaag aacgatacac atactgattt ttcggagcag
    12541 agactttctc agcgtttgta acaactacag atgggatttc acgcttgaat ggttgataat
    12601 agtctgattg gatggttcct tctattttat accattcatc atttttaacc gttactcctt
    12661 ccggcatatg cgtcaacaaa ccaaagactc ctgaatctgc cacacaatgg ataatgccga
    12721 atcggaacaa gaagatatct gtattgctat cgttcggtgt ttggtaaaca aatccttcat
    12781 agctgatttt tttgccaatg aattcgctag ggtaattata aattagctcc ataacttcta
    12841 aatagttttc atctgtgatc ttgatagttt gcttatcccc atacttttct ttcaactcat
    12901 tcatttggtc taagtagtct gatttgttga aataaatact ggtatccggc tttaagtatt
    12961 gtgtctgcat ctccggatcc cctactgatt ctttacttac tgggaaatta aatcctttgg
    13021 cttctacgat cgtagtgtcg agactaactg ttggaaacaa cgtccccacg attactggca
    13081 aagctagcag tacataagcg attccacgtt gataaggttt tgacaaccca tggtcatgat
    13141 cgtgctcgtg tgccttttct tctgcttttc cgtttttgac ccacaaatac agctgaacta
    13201 aagccaaaag agcagataaa atcattgaaa gaatagctaa gtagcgataa tggacattga
    13261 tatattgatc gagtttgcca gaaacttgca agtacatcat caattcgaaa tacccagata
    13321 aaatcaaaaa ccgcagcata ttttccctcc taaataaata atgtgaatcc aataacgcta
    13381 agggcaatca gtccgatcag cgataaaata aagcgtcctg taaaatatcg tttcatcatc
    13441 agtagatttt tgatatcgac cattgggcca aagaccaaaa aggcagctac aggtgctgtg
    13501 ccgaacagac ttaacaaaga agatcctata aacgcatctg cttctgagca aagagacatc
    13561 gtaaaggcca ataacagcat gatgataatg gctaaaatct ttgttgagcc gagcgttagc
    13621 ataattctag ttggtaaata agtctgcatc gcagctgcga ttaatccgcc aatgatcaaa
    13681 taacgacctg tatcaaaaaa ttcgtcgatt gaatgtgtca acacatgccc agtttgatgg
    13741 atcagctgat tttttggttc attcttctca ctttgttctt cttcatggac atgatgatgg
    13801 tgattttctg ctactttaga cgtgattttt tctttcaata cagcgtcttt ttgaaaatag
    13861 gcaagccaga caccaatcac aagggcaaca aaaaagctgc ctatcacccg ccagcttgcc
    13921 atctgccaag aattgccaaa tgcgataaaa gtggaaaaaa tcacgattgg attgatgatc
    13981 ggagcagtca gcataaaagc aaacgctgtg tgaactggta cgcctttttt aacaaattga
    14041 tgaacgatcg gtacgatgcc gcattcacat gaaggaaaga aaaatcctaa gatcgaacca
    14101 gtaaaaatag agaagatacg attttcagga agccatctct tcacacgttc tggggtcaaa
    14161 aatacttgta aggcgcctga gataagacag cctaataata cgaaaggtaa tgcttcaata
    14221 acgatcgata agaaaatcgt actcatctgc aaaaccgaat ttggaataaa agaaaacatg
    14281 agtttcctcc tttttatttc tagttcattc gctttgcaaa tatacgcttt tattcaaaaa
    14341 aaacaagttg ctctgtaaat ttttacacaa ctcttatttt ttaccaaagc acttcaattg
    14401 actttttctg ttattcccat taaattaagg tctcatacat atcacttcta tcataaaagg
    14461 gagaataaaa atgaaacaaa ccactaactt gactgaagtt caagacatac tgcaacagtc
    14521 atccgttgcc gtcatttatc tttcgatgcc taattgcagt gtttgtcacg ctgttcgtcc
    14581 acgactagag gaacttctca cacattatga tattccggca cttcatttgg atgcatttga
    14641 aacaccagaa gtagctagta aatttgaagt gctgactgcg ccagttgtcc tgatttttca
    14701 tcaaggaaaa gaagtctttc ggcaagcacg gttcatcgac tttaaaaaaa tccgttatct
    14761 actagatgaa ctgacagcag aagatgattc cctttcttat gaagaaatct tccgaacaaa
    14821 ataatcgttg tccaaacaga aaaaagcgat tgaacaagtg aaagttttgc cttcatttgt
    14881 tcaatcgctt tttattttta ttctgctgta ttttcggaat gcgcatttgc gtcagaatgc
    14941 aagaaataga tcaaggtttg caattcattc gtcaaatcaa cattttggat caatacatct
    15001 gacggagcat tcaatcgagc agcggtaaag ttcaagattc ctttgattcc tgcttccgtt
    15061 aactgattga ctacttcttg tgctctttca gcgggtatcg ttaaaattgc tacttcgatt
    15121 tgttggatct tgatttgttc tgacatatct tccattggat aaacggggat accgtctacg
    15181 atgcgcccaa cgatttcctc attcacatca aaagcacaac tgatacgtat gctattactt
    15241 tgatggaatt tgtattttag taaagcactt cccaagttcc ctacaccgat cagcgcaaca
    15301 tttgtcaatt gatcgtcgtt taatgtcttt gcaaaaaagt gcataagatc ttctacatca
    15361 taaccatacc cacgttttcc taattcgcca aaataagaaa aatctcgacg gatcgttgca
    15421 ctatctactt gaacggcttc acttaattca gttgaagaca cttttttctt tccagcatta
    15481 tttaaaatcc ttaaatagcg ataatacaaa ggcagtcttt tagctgtcgc ctttggaata
    15541 atatgatctt tcacgaaatg acctccacgt attgtctaat tacatctttg atttctccat
    15601 catagcagta tttataggaa aaaatcaatt ccattgctca gatattgtga aattttattc
    15661 tttattcatt tatttatcat ttctgcaaat ctcgcagtat aatggaattt atggtagact
    15721 actaattgaa aaatagtttt ttatttgagg agaattcaca aagtagaaaa gaggattcca
    15781 tgatattatt acaagccaat cagattgctc gccattttgg tgcagaagtc ttatttgaaa
    15841 acatacattt agaaatcagt acaggcgctc gtgtcgcttt agttggcaga aatggcgctg
    15901 gaaaatcgac tttattaaag atcattgctg gaattgaagc acctgatgaa ggaaagatcg
    15961 ctaaaaataa aacagcgact ctcggatacc tcgctcagga cacaggactt gattccaatg
    16021 aaacagtttg gaacgagatg ctgaaagctt ttgaacaagt tagacaaatg gaagagcgga
    16081 tgcgcgagct agagattttc attagcgaag gtacgccaga cacacctgct tatagttctt
    16141 atttaaaaga atacgaccgg ctgcaacacg atttttcaga tcgaaacggc tatggttatg
    16201 aaaatgaaat tcgttccgta ttgcatgggt ttaaattcga ttcttcattt tatgatcaga
    16261 aaatcgatac tttatcaggc ggacagcgca cacgtttagc tttagctcgc atgcttttgc
    16321 aacaccctga cattttgatt ctagacgaac caacgaacca tttagatatc gagacacttt
    16381 cctggcttga gaattatctg caaagctata ctggtgcatt attgattgtt tcccatgacc
    16441 gttatttttt agataaagta gtcaatgaag tctatgaatt aagcagaaga aaaatgcgcc
    16501 attacaaagg taactattcg aaatatctag atttgaaagc agaacagtta gcaagtgaat
    16561 ggaaggctta tgaaaagcag caaacagaaa tccataaatt agaagacttc gttgctcgga
    16621 accttgttcg cgcctctacc acaaaacgag cgcaaagccg cagaaagaca ttagaaaaaa
    16681 tggaccggct ggatcgtcct caaggggatg aaaaacaagc aaactttcta ttcagtatag
    16741 aaaagccttc tggaaatgta gtcttgcaaa tcgaagatgc cgctatcgga tatgataatg
    16801 tcaccttatc tgaaccaatc aatctagata tccgtcgtca agaagcgatt gctctagtag
    16861 gtccgaatgg tatcgggaaa tcgacgttgc tgaaatcaat cattcaccag atccctttta
    16921 tccgtggaaa agaaacgcta gggacaaatg tcaccatcgg ctattacgat caaggtcaag
    16981 ctgatctgca tacaaacaag acgatcctag cagaattgtg ggatgagcat cctaccactc
    17041 cagaaaaaga gatccgaagt gctttaggtg ctttcttatt ttctggcgaa gatgtagaaa
    17101 aaccaatccc tctgctaagt ggcggtgaaa aagcacgggt tgctttagcc aagttagcga
    17161 tgaacaaaga aaattttttg attttggatg aaccaacaaa ccatttagat attgacaaca
    17221 aagaagtatt agaaaatgca ttgatcgatt atgacggcac actgcttttt gtttcccatg
    17281 accgatattt catcaatcgg atcgcgacaa aagtcgtcga actctctgaa aatggcagca
    17341 aagtctatct aggagactat gattattatt tagagaaaaa gcaggaagaa gaagaaatcg
    17401 ccgaattgtt ggcacaagat gagccagaat ctgctcctgc tcccacgaac aaatctgatt
    17461 attaccaaag caaagaacag caaaagctta tccgtagcct tcaacgaaaa attactcagg
    17521 ttgaagaaga aatggcgcgg atcgatgaat ggatcgatca gttggaacaa gaaatggtcg
    17581 cgccagaaaa cctggaagat cacgtaaaac tcaatgagct gaaccaagat ttagaagctg
    17641 ctagacaaga tcaagaaaca aaattgacgg aatgggaaga actaagcttg gaattagaag
    17701 aatatgaaaa ttaacgaaaa aaccaaaaca gaaaccattc atgctgtttt ggtttttctt
    17761 tttttatttt atcaaacaaa aattccatat ttaccttttt caccaataag aagaccaatt
    17821 actagtcatt ctcactaaag cttctaaata atagtaatca ccccaaatac aaggtgtatt
    17881 taccccatta tttttgggct tattataaac agactgtgtt aaaaagccat cttcttcttc
    17941 cgttgtagca tatctttctt tcaattgtcg cataattttc caaacagcag actggtataa
    18001 gttcttttct gttttgtcta atagacctga ttctattaat tctaataatc cacaaaccat
    18061 gatcaccata ctagatgtat ctttttcttc tctgctagaa tcatcaaaga tcaaatccca
    18121 ataacaaatg gtatcttctg gcaaccgatt cataaaataa ttggctaata ttttgcttaa
    18181 atcaaaatat ttttgttctt tcaaataacg ataacttaat gcaaaaccgt aaatccccca
    18241 tgcttggcct ctagcccaac aggaattatc actataacct tgatgcgtac ttccatatct
    18301 tggttttcca tctttgacat ccatataaaa tgtatgataa gttgaaccat cttctcttac
    18361 taaataatct gctgcatttt gaatatgagc ctgagcagct tttttatatt tttgatttcc
    18421 agtttcttca ctcgcccaat acaataatgg aagattcatg caacaatcca tgatcattct
    18481 accttgttgt gaaggatcac taggatctcc ccaagcttgt ataactcctg ccttctccca
    18541 aaaacgctga agtaatgttt ctgcagcatc aattgaagct tccttcattt ttcgatttcc
    18601 cgttatttta taatctgcta cggttgataa agaatacaaa aaaccaagat cgtgatgatt
    18661 agtgataatt tgacagtcaa tcctgtggat aaaatctata tctgcttttt cagctgtttg
    18721 ttgaaataaa ggatcacccg tcttctcaaa taacaaccaa ttaattcctg tccaaaatcc
    18781 ttctgtccaa ccaatattgt ctcttaatgg ataacgtcct tttataggac actcgcttgg
    18841 gaattgatac tgactgttac tgatacgttt gattaacctc tccgtgtgtc tgcgacaacg
    18901 ctcgatctca ttattccatt ctttttccat taattcttta taacattcat ttatccattt
    18961 ttctggatgt attatctctt caaacatcac tttatcaagc atttccccac cagcctttag
    19021 cataatttta gtcttttttt attgttttta ttttggatag ttagcccggt tgtcccatca
    19081 aaatcaattt taggacgatt gttccatact tctaaactat aatcccgatc ttgatgagca
    19141 accactcctg ttccgagcca atgggttcct tttccaaatg taccctctaa tccaggaata
    19201 aaagtgtttt cccatgtcat caagtttgta ttgggcaaac ccataatagc tgtggatttt
    19261 cgtttaatag tatcgtcact taaacagata atacctgaaa agccagcttc actcacccta
    19321 tagttttcct tgtcttcttc tatgattatt ccttctttct caggagaaca ttcaatagca
    19381 aaccctgtct catatagaac atattctgta tctaattcta ctttgtgtac gcgaatctgc
    19441 cagccttcaa aaggaataag ccaagttctg atttttgcct gtaaagtagg ttcccatgta
    19501 gaggcaagta cctctttctt acatacaatg tctcgtacat tatttcgaac gatgaactgt
    19561 ccataggttt tgatgctctc attcttaaaa ctggtcgtga tatatgtgtc cgctcgctga
    19621 atccctagca ttgaatccat tgccatttct gctttcaatt gattcgctcg cggtatcgaa
    19681 aaaccaaatt gactagaata agcaaatttt aaatattttt cattggtcaa tgtatggaaa
    19741 tttggcccta attgtcccgc attcaaaaaa aatgtatgtc cattatcatg ttgtatgagc
    19801 aaattggctt ctgaaagaag tttagttcct tcacgaatag gcataggcat ttctttagcc
    19861 gtccaatact catggtcttc aggtagcgcc aacaataaaa aaatcttatt cagccataat
    19921 ggagataacg tactattata gggttcagtc aatgtcaatt gagggtaggt ataaccaata
    19981 ttcaggatac ctttttcatc aaatatttct ttttgcatcc accatcttat attccgattg
    20041 actaacccct tgatttcacc taatttaaaa ggcaaaagat cggcccacaa catagctgac
    20101 caaaagcttg aaactgcaaa acgataaatc atgcttcgac caaaaggcac atttgcacca
    20161 tcttccgcaa aaaaatgaat atagtctcta gaaaaatcaa tagctcggtt cttatatatc
    20221 tggctaatgg gcttttctgg ttctagtacg ctataaatca aaccataata atgaaatgca
    20281 aaaggattat aataatcttg gcgacctctt gaactgtctc gataccagcc attttgaaga
    20341 taacaatttt ctatattatc aaatgcttct ttcagtgctg attctttaac tggataacca
    20401 aatttttgga taattgttcc gacaattatc ttaaaaaatt gccaattacc atctgcacat
    20461 tcatattcaa aaatttgcga gaaccaatga ataatctggc ttttttctcc tgtatctaat
    20521 tttttccata ataattgttc atgatgatat aacgctaata acattgcggg catttctacc
    20581 atacgctggt ctctttcatg tatttctccc caataatcgg gatgggaagg atctgttcca
    20641 gcttttattc ctgatagaat taatttcaac catcgttcat ctaattggtc aattgcgggc
    20701 cccgctcccc ataaaacccg agagaatcct tccattcctg caattttatt tccatatcct
    20761 accccttgat gtatataatc aatttgtgcg ccacttgctc gataaaacgg ctggagtggt
    20821 tgatttatct ttttaaataa gtcaaagtaa tcctgtctgg tccttaatag tggtactgga
    20881 tgtttcattg tattttctcc tctttttact accaaatagc taattccgac tgttctaatc
    20941 gaagtaagcc ttcaataaaa aaataatcag aatagatcag tggcacatta taagtcagtt
    21001 ctctatggta tgcttctgct ccgcctccaa tgatcccatc ttcatccata ttccaatttg
    21061 catagtgctt ttctgtcttt tggagtatat tgatagcagc ttcatgatac atttttgatc
    21121 gtacagagga aacatatcct gctaattcca gaagaccgca tgcagcgcat actccagcac
    21181 tggtatcaat attcgaatct tttacagcaa aatcaatgag aggaatataa ccagtttttt
    21241 cgattttctg aataaaattt actgctatct tttctgctat agctagatag tacggatttt
    21301 ttgtgtaacg ataacttaac gcgaatccat ataaagccca tgcatttcct ctgctccaac
    21361 aagaattctc attgtatcct tgcccgccaa gtaaccgaat atatttccct gattctgcat
    21421 caaattctgc gatatgcccg gttgatccat ctttcctcac tagatactta gctgttgtat
    21481 ctgcatgctg ccgagcaatt ttagagaacc tcggatcacc agtttccctc gaagcccaat
    21541 acagtaatgg taaattcatc atactatcaa taatcatcca accaggttta tggtcattcc
    21601 atgctactaa atagttccct gaaatattat agcgtccagc aagtaccgta gctgcatgta
    21661 accctagttg tcgactatgt ttgttttgag actgttgata atgtgcaata gccgatggta
    21721 agaataaaaa acctacatca tgatgaacgt ctgaaaaatg gtacagggca gattctaata
    21781 attgttcttg ttgtattgct gcctctttga acttttctcg ttttgtcttg tgaaagagct
    21841 gccataaaat accactccaa aaaccattgg tccaccagtc gattcctctg tcctttatta
    21901 cgtctgtata ttttccgttg taagaaatat atggaatttt attccccatt ctgtctaatt
    21961 ccgcatctat cttttcagaa gctacattca aaatttttct tgaccattcc ttcgtctgtt
    22021 cattcatgga tatcccgcca ttcttttaat ttttatgaat gtggagttgc tcctagaacg
    22081 aactagatgg ttaacattcg ttattttttt tacttatttg cagctccaat gtcattctcc
    22141 ttaaatttag actgcgccca cacataaatc aagaccattg ggatcactga agttgctaaa
    22201 attagcataa ttgcgccata attaattggc tcacctgtac tagaaaccgt catatttttg
    22261 ataattaagg gaaccgtata tttatcttta tctgaaagca tgactaatgg aaatagatat
    22321 tgattccaac ttcccataaa gataagtaaa ccactagtaa taatcgtagg tgataaaatc
    22381 ggtacagcga ttttcgtaaa aatcacccac tcattggcac catcgattct ggcagcctcc
    22441 atcagtgctg taggaaattg actgctatat tgtcgcatca taaacactga agttgtactg
    22501 gcaatcgaag ggatgatcac acctgcataa gtattcgata atcctaaacg actcataatg
    22561 taaaataaag gaatcaatgt ggtaaaaaaa ggcaccatcc tagatagcat aactgtattg
    22621 aacaacagtt tattccccat aaaacgatac tttgctaatg cataacccgc cattgtagaa
    22681 ctggctgtag ctgaaactgt actgattaca gcaataacaa tcgaattcca aataatcaag
    22741 ggataattat atctcgccat gatggcttgc cagtttttta atagcatatc cccaaacttg
    22801 aaattgattc cgccacttaa aatttcttga ttactttgcg ttgaagctac aatcatatat
    22861 aaatatggca tcaaaaatat taaggcacca aacacaataa tgacgtacgt aaaaattctg
    22921 ctttgtatct tttgtttagt catttttatc acctccgaat ttaaattgaa tagccgataa
    22981 tataacagat acaaacacca tcgtccaggc aatagcagag gcttttccaa aatcaaccat
    23041 ttcaaaactt gttttatata aattgactcc tacgaccaaa gctgaatttt ctggtccatt
    23101 ggaagtccca aagaatatat ttgggatatt gaaattaccc aagccattga tagtggctaa
    23161 aactgtggcc attaaaatga ttggctttag catggggatc gttaataaaa agaattgccg
    23221 aaatttcgat gctccatcta tttcagcact ttcgtatatc tctttagaaa tcccttgaag
    23281 accagctaaa aataaaatag tgttatatcc tacactaagc caaatcatcg tgatgatcat
    23341 tgatattcgt atccaaaaag gatttgttaa ccactgtaca ccgttaattc ctagcgcatt
    23401 caaaaatcca ttgaataacc cagtcggatt gaaaaaagtc atgaatacgg aagctacagc
    23461 caccgttgat gtaatggttg gaatataata gacagttcta aaaaatcctt ttccttttaa
    23521 ctgtgctgaa ttcaataaaa cagcaaagta aatagctaat agcatcgtta ttggaattga
    23581 tcctgccatg ataatcaaaa cattcgtgta agatttaata aacaatggat ctcggaagat
    23641 agctagataa ttgtcaaatc caacaaattc aaatgagtag ccaattttca taaaactaaa
    23701 agcaaacgag ataatgatgg gaatcaaaat cgtcacaata aagaaaataa caaaaggtgt
    23761 gaccaatcca taagcacttt ttttatgaga cgtatctgtt gcttttttct tgctgttctt
    23821 tattgtcttg cttggtaacg aagattgcat catcgttaag tcctcctaat attttttaat
    23881 caccagttaa ttttacgccg tacttatgag caaaattttc tgcttctttt agatatgaat
    23941 tttcaaaatc acctgtttgc caatagttat atgcagcggt agtcaaataa gacgtagcat
    24001 ctgaataagt ggctggtaaa acagtatttg atgtattttc attgatttta ttcaatagtt
    24061 catagtattt ttgtcctcct tagtagtcaa actttttctc agctgcttct gtttgatagg
    24121 ccaatgagtt agatgtagcc acgcccagct ccagtgcgtt ggctaagcat tcttcatctg
    24181 tcagcataaa tgtaagaaat tgttgtgcca cttgtggatt tttggcatct ttagggacat
    24241 aaaaacttga tcctcctgat actgcacctt ttcctggatt ttcttttgaa aaaggaatca
    24301 gtggagccat gcgccatttg tcagatgcat caggaaaatt caaagacata ttcgtagcat
    24361 accagccgcc agcaacaaac attgcagatt cttgaaatgc tttctcagca tcttgtgcac
    24421 cgtagaaatg tacaatatct gagtcgatca tttctttgat taactttgca gcatgtttcg
    24481 cttctttagt attcagacgg atatttcctt cttcatcaag caaagattga ttctgctggg
    24541 ctagcatgtt gataaacaat tcttggtccc cagattctgg caaggcaatt ccaaaactac
    24601 cagttttttc ttttaatgct tttgccacct ggatatattc ttcccaagaa ctgatttctt
    24661 caaaatctac acctatttca gcaaattttt ttggttgata ataacaaagt gctggggtaa
    24721 aatcactagc ccaaggaata atcgtttcat tactcgtttg ttgacgcaaa atattcaatt
    24781 tttgatcata aaactgatcg ccatatttgt cataaaatcc atattcatca gcactataaa
    24841 aagcatcttg aaatttttcc agcacacctg ctgctgaagt gtctgccatg gagataatat
    24901 ccggcatatc ttcgtgtgtt accaattttg gggtgatcat ttgtactgtt gctgttcccg
    24961 aagctacatt cacaattttt aagtcaatat ttgctccagt tttgcggtta tagatttttg
    25021 cagcattttc aacatagttt gtcagtttgc cgtttgcgac atatacttct aatgtagtgg
    25081 ctttttttat cattggatct gcgatgtttg ctgttacttc ttcgttagtt tttccacatg
    25141 cacttaagct gaataatagg gtaatgttta gcaaagctat caccaatttg tatctttttt
    25201 tcatgtctat cccttctttc ttttcaagtt cttatataaa acgctttcac ttatgtatat
    25261 taacggaatt agtaacacaa atatttatat aaaaaaatat tttacttgtc gttttggctt
    25321 ttcatttttg ttataatagt cattaattat aaatagaaag ctttttatat aaaaagagaa
    25381 aggaaagtgg ttcttttgtt aacaaacaac caatcctcca atcttgtcaa aaaaacacta
    25441 acctattcca tagataccca tcttcattta tctgctgctc cctattttcg actactaata
    25501 aatgaaagcg ctaatttata tgctgaattt gcacataaat ctatagaact agataatcct
    25561 tcccttttat tcattgataa acagcaagaa gtccaaatct tttctactca aaaggaaaca
    25621 caaactttta tcattatcca gttttatttt gatgagcaat tattagcaca tattacggga
    25681 caatcttttt ctatagatca agaaataaca tctatcatta cttttctgaa aaatgaacag
    25741 ttcaaaattg attatctaaa acatagtaag ccagctattt cctatgatca ggaaatcaat
    25801 tcttttttca tactatgcca acagatgagc attcatttgc tttccttatt agttacttat
    25861 tgtctgcaaa aaattcaatt gtcttcctta ccaaggcatt atcaacagga acttgcttta
    25921 ttgacaatac cttcaaatga gaaagtcatt cctaaaaaaa agcatattct ttattcagat
    25981 gaattagttg atccaatcat acgatattta gaagaacatc tttcagaaaa ttttttgctt
    26041 gaacaattag cccaaatttt ttttatcagt ccagccagct taaaaaaaca ttttagaaaa
    26101 gtgaatggaa aaagtgttat tagctatttt aaagaactaa aaatggaaaa agcaaaacgt
    26161 ctcgtgctag aaaatgaatt aacctataca gaaattgcag atatattagg atttcattcg
    26221 atccatcatt tttcttcagc ttttaaaaaa tatacagggt tatccccttc aaagtattat
    26281 ctatccttaa aatagaaaaa aatttttagg ttttatccac aaattatttc tctatatttt
    26341 ctgtctattc aaaataaaca ataattttcc ggcacaatta tttgctgttt tttaccataa
    26401 catagtacga tcaacgtaga aaaggagatg tttttatgaa agttgttgtc attggcggtg
    26461 tagctggcgg tccttcattt gccactcgtt tccgtcgatt gaatgaagcg cacgaaatca
    26521 ttatctatga acgcggagaa aatatttctt atgcaagttg tgctttgcct tattatttag
    26581 gaggtgtgat cactgaccgt gactcgctga tcgaacgtac accagaaata ttgaaaacaa
    26641 aaaacaacat cgatgtcttt actaaacacg aagtaacagc aatcgatcct tctactaagc
    26701 gattaacagt taaagaccta tccacaaatg aagaaataaa aacagattac gataagttga
    26761 tcatctcttc tggtgctaga ccagattatc cggatattcc cggagttttt gaagcagaaa
    26821 acggctttgt cctccgtagt gtgacggatg cggatcgaat caaatcgttc cttgaagaaa
    26881 aaaatccaca acatgtcgtc attcttggtg caggtgttat gggtctggaa ttagctgaga
    26941 atttcaagca tcgcggctta gacgtgactt taatcgatca attgccacaa gtcgctttcc
    27001 cttatgatcc agaaattgct aatttagttt atgacaaatt gctgaaagaa ggattagccg
    27061 ttcatttaga aacaagagtt actgagatcc gtgataaagg tcgagaaata gtattatcag
    27121 atggctccgt cctttctgct gatatgctaa tttttgctgt tggtgtttct ccgaagaatg
    27181 aagtggtgaa agcaaccggc atacaattat cagatacagg tcagatcatt gttgatgacc
    27241 agttacaaac caatctgccg gacatctatg cgattggcga tattatcgaa acgactagtg
    27301 tagtgactgg tcagccgatc caaagtatgc tttccagtgc ggccaatcgt caaggacata
    27361 tgctggcaga tattttaaat ggtacgccta tgcgctatcg cggatatatt ggtgcaggtg
    27421 tcgcaaaaat ctttgatcat acagcaagtt atgcgggaat gacagaacat gaattaaaag
    27481 catcaggcat aacaaattat aaaactgttt ttatcactcc ctttgaccat gcctatttct
    27541 atccagaagc tacaagatta aatctaaagc tgatttttga tgcagatagc ggtcgtattt
    27601 taggtggaca agcatttgga gaaaaaggtg tcgataaacg gatgggagaa ctttctgtag
    27661 caatcaccgg aaacttgaca gtctttgatt tgcctgattt ggagttgcct tactctccac
    27721 cgtattctac tacccgtgac ccgttgaata tagctggtta tgtcgcaatc aatcaaatga
    27781 cgaatatcgt agaaacgatc aaagcaagtg atatacccga aaacgatttg aaagaagcgt
    27841 tctttttaga tatacgtgaa cctaataaag caccttctgg cagtatctcg gcaacaaaaa
    27901 atattccaat gaatgagtta cgagatcgaa tcaatgaaat cccaaaagat aaaaaagttt
    27961 acattacttt cagaagagga ttgaatactt atacttctgc ccgaatcttg gcaggtttgg
    28021 gtatcaaagc gattttgatt gaagaataaa aaaacgaccg cggtgggtag ccgcggtcta
    28081 ggagttattt ttacttgagg agtaaaaatg aaaaagtata tagggttgtt ggttggtatg
    28141 tatatagaat agaagataaa tgtgaagaaa ttgtgcatta tttcttcaca tttattaggt
    28201 tatagtttaa gaaagtttaa acattgcgca atttaattat tttagctgtt tcttttcata
    28261 aaaaaacatg ttgtgactct gagacaaatc atagtccata gtgatgtctc tagagtaact
    28321 acgcctaata ttacgaggca tcatattaat ctatcagcac tagtacctaa actagcatcc
    28381 ctttcgaata ttttttctta tataataaag tttgctttca ctcctctaat ctcaccaaat
    28441 cgactggctt gcgttgtgtg atactaggaa ctgattggtt tagaacgact tttctattgt
    28501 aatcatattt ttcgccatcc tcgttgtctt ctaatccttc aatgaatgat ccctaatgtg
    28561 tgtattaaat aatttaattt ttttgttcct atttatttaa ca
//
LOCUS       DBBGRF010000035        28306 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000035 DBBGRF010000000
VERSION     DBBGRF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.035"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            8..81
                     /locus_tag="ACIZD4_001756"
     tRNA            8..81
                     /locus_tag="ACIZD4_001756"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="ACIZD4_001757"
     tRNA            101..173
                     /locus_tag="ACIZD4_001757"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="ACIZD4_001758"
     tRNA            201..274
                     /locus_tag="ACIZD4_001758"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="ACIZD4_001759"
     tRNA            288..361
                     /locus_tag="ACIZD4_001759"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="ACIZD4_001760"
     tRNA            385..474
                     /locus_tag="ACIZD4_001760"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="ACIZD4_001761"
     tRNA            487..560
                     /locus_tag="ACIZD4_001761"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="ACIZD4_001762"
     tRNA            579..654
                     /locus_tag="ACIZD4_001762"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="ACIZD4_001763"
     tRNA            656..726
                     /locus_tag="ACIZD4_001763"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="ACIZD4_001764"
     tRNA            740..813
                     /locus_tag="ACIZD4_001764"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="ACIZD4_001765"
     tRNA            838..925
                     /locus_tag="ACIZD4_001765"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="ACIZD4_001766"
     tRNA            947..1018
                     /locus_tag="ACIZD4_001766"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="ACIZD4_001767"
     tRNA            1041..1130
                     /locus_tag="ACIZD4_001767"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="ACIZD4_001768"
     tRNA            1143..1216
                     /locus_tag="ACIZD4_001768"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="ACIZD4_001769"
     tRNA            1235..1307
                     /locus_tag="ACIZD4_001769"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="ACIZD4_001770"
     tRNA            1311..1383
                     /locus_tag="ACIZD4_001770"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="ACIZD4_001771"
     tRNA            1388..1458
                     /locus_tag="ACIZD4_001771"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="ACIZD4_001772"
     tRNA            1471..1544
                     /locus_tag="ACIZD4_001772"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="ACIZD4_001773"
     tRNA            1556..1627
                     /locus_tag="ACIZD4_001773"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /gene="metK"
                     /locus_tag="ACIZD4_001774"
     CDS             1893..3086
                     /gene="metK"
                     /locus_tag="ACIZD4_001774"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGC5990692.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="ACIZD4_001775"
     CDS             3216..4688
                     /locus_tag="ACIZD4_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HGC5990693.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="ACIZD4_001776"
     CDS             4771..5559
                     /locus_tag="ACIZD4_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC5990694.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="ACIZD4_001777"
     CDS             complement(5626..6294)
                     /locus_tag="ACIZD4_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HGC5990695.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="ACIZD4_001778"
     CDS             6409..8121
                     /locus_tag="ACIZD4_001778"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990696.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9893
                     /locus_tag="ACIZD4_001779"
     CDS             8124..9893
                     /locus_tag="ACIZD4_001779"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990697.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10098..10664)
                     /locus_tag="ACIZD4_001780"
     CDS             complement(10098..10664)
                     /locus_tag="ACIZD4_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC5990698.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(10664..11620)
                     /locus_tag="ACIZD4_001781"
     CDS             complement(10664..11620)
                     /locus_tag="ACIZD4_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HGC5990699.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(11620..12276)
                     /locus_tag="ACIZD4_001782"
     CDS             complement(11620..12276)
                     /locus_tag="ACIZD4_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGC5990700.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            12646..14664
                     /locus_tag="ACIZD4_001783"
     CDS             12646..14664
                     /locus_tag="ACIZD4_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC5990701.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    14734..14940
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15091..17505
                     /gene="leuS"
                     /locus_tag="ACIZD4_001784"
     CDS             15091..17505
                     /gene="leuS"
                     /locus_tag="ACIZD4_001784"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGC5990702.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            17853..19406
                     /locus_tag="ACIZD4_001785"
     CDS             17853..19406
                     /locus_tag="ACIZD4_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HGC5990703.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(19787..21571)
                     /locus_tag="ACIZD4_001786"
     CDS             complement(19787..21571)
                     /locus_tag="ACIZD4_001786"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990704.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(21586..23307)
                     /locus_tag="ACIZD4_001787"
     CDS             complement(21586..23307)
                     /locus_tag="ACIZD4_001787"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990705.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            23407..24168
                     /locus_tag="ACIZD4_001788"
     CDS             23407..24168
                     /locus_tag="ACIZD4_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC5990706.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            25135..25403
                     /locus_tag="ACIZD4_001789"
                     /pseudo
     CDS             25135..25403
                     /locus_tag="ACIZD4_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            26075..>28306
                     /locus_tag="ACIZD4_001790"
     CDS             26075..>28306
                     /locus_tag="ACIZD4_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HGC5990707.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         8928 a         5058 c         5987 g         8333 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa taaagaggtt
     9901 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag cttctcatgt
     9961 ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt gaataaagag
    10021 gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac atatcattta
    10081 tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg cggctggttc
    10141 ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag tttggaacaa
    10201 aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta gacgacaagg
    10261 atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt gcgtgtagtc
    10321 tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt gaaaatccct
    10381 gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc ttgtagaaac
    10441 aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc atcgattgct
    10501 tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc tgctagaaaa
    10561 accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg ttgcaagatt
    10621 tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg ctcacctttt
    10681 tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca tcaattgcat
    10741 tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc cacggcgcat
    10801 cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg tcgcaaatga
    10861 cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag tcccgcaaca
    10921 ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata tctgaatcta
    10981 aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt aatccgttga
    11041 tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca tctaaataag
    11101 tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt gtttgcaatc
    11161 caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca actacttcat
    11221 ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt aaattgacta
    11281 cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta aaattttgga
    11341 aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg atttctttct
    11401 ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa ccagatacac
    11461 tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag tcaaatcctc
    11521 catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg taattccaag
    11581 aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct tctttctgta
    11641 agagttatct atttgttttc ttttttctct atacactgga taagtcaggc acagccaaga
    11701 aagactgagt aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca gataaatgcg
    11761 gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg tgcgtaaggt
    11821 tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa tcatactgcc
    11881 tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg ccaatgaagg
    11941 acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa ttacaataaa
    12001 tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc ataaagccgc
    12061 acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa agagttggta
    12121 gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat cgaaaccaga
    12181 aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga caagaaagaa
    12241 gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt gaagcaatga
    12301 cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac caatgtatga
    12361 ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga aagacatttt
    12421 ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa tccttttaaa
    12481 caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt acggtaaatt
    12541 acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat attaagagaa
    12601 gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga aaacattgca
    12661 agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa acgaggggca
    12721 gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt acagccggtt
    12781 cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac agcggcattt
    12841 atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct atatgcatca
    12901 gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt atctcaagca
    12961 ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt ctacatggat
    13021 acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg acaatatcct
    13081 tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc atttggcaac
    13141 ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga tgcgacagct
    13201 tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa taatatcatc
    13261 gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg cggtggagcg
    13321 actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag caattctggt
    13381 aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg tgattctgtt
    13441 tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg gaacaacatc
    13501 caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca ggaaaatggc
    13561 tcttcgacga ataattccgg taacaatacc aattcttcag gaaatgctgg tacatcaaac
    13621 ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt ttggaagatc
    13681 tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat caagaacaat
    13741 ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa tgctggagca
    13801 aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc aagttcttct
    13861 aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg gagcgtctca
    13921 aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca aaataacttt
    13981 atctacccag gacaacaact gactgtttca aacagtggat caacaaacag cacgtcaggt
    14041 aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg cagcagttcg
    14101 tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc aaataaaaac
    14161 ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt catttatcca
    14221 ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg ttcaactact
    14281 tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc atccactggt
    14341 aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa caaacatcat
    14401 atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat ctatccagga
    14461 cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc agttactggt
    14521 tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga cagtcatgga
    14581 attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat ttatccaggt
    14641 caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt gaattccaca
    14701 aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg aagtagtaaa
    14761 aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc ttttgaactc
    14821 gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg gccgttacaa
    14881 cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta cgtcctataa
    14941 aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag aaaacaaagc
    15001 aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat aatagaaaca
    15061 agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga aattgagaaa
    15121 aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga tcctgaaaag
    15181 ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct acatgtaggg
    15241 catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag tcaaggatac
    15301 aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca atatgcgcta
    15361 gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt ccgacgccaa
    15421 atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac tgatccggag
    15481 tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct agcttatgaa
    15541 gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa tgaagaagtg
    15601 atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat gcgccaatgg
    15661 atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt agttgattgg
    15721 ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg agcaaatatt
    15781 gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg accagatact
    15841 ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag agaaattacg
    15901 acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa aaaatcagat
    15961 ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc ttatgcaatc
    16021 aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt atcttcatac
    16081 ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga attcgctcaa
    16141 actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa agctgcttac
    16201 acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa acaagaagca
    16261 atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga agtcagctat
    16321 cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat cccaatcatc
    16381 cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt acggttgcct
    16441 aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa tatcgaggag
    16501 tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac gaatacaatg
    16561 ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca taacaaaaaa
    16621 gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta cattggtgga
    16681 gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt cttatacgat
    16741 atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg aatgatctta
    16801 ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc tgatgatgtg
    16861 gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg gccattagat
    16921 gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt ggatcgtgta
    16981 tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac attgaatgat
    17041 ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga ctatgaaaat
    17101 cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc ctataaagtg
    17161 gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc gattgctcct
    17221 cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc ttacgcacca
    17281 tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt tttccaagta
    17341 aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga tgagctagaa
    17401 aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac agtcagaaaa
    17461 gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc tctttgtcaa
    17521 taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca ttctgtctca
    17581 gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga ttttcatgtt
    17641 ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct ctgtaatcat
    17701 caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga aattgagagt
    17761 acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga ttttgacgca
    17821 taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt attatcgaag
    17881 tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa agaataatgt
    17941 tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct gtatcgttcc
    18001 tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa ttaaataatt
    18061 tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt gtttttcttc
    18121 tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg cttagtcaaa
    18181 gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat ctttattttg
    18241 agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag ttattgctga
    18301 gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc ggaatgaaca
    18361 cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag tcttcgcctg
    18421 gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc attcttttag
    18481 ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat ataaatgctg
    18541 cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca aatgaagggt
    18601 tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat gatctcaaac
    18661 ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat tgggtatttg
    18721 tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg gggctgattc
    18781 ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca tggtttatct
    18841 attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa acatggcaaa
    18901 cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta ttttatggca
    18961 acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact ttgtacattt
    19021 acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg atcaatcagc
    19081 cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca cgtgaaagtt
    19141 tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg attccggaaa
    19201 actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact caaataagcg
    19261 cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat gcagggaaaa
    19321 tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc gttcagcaac
    19381 tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg ttcagcaccg
    19441 agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt gtaactcgtg
    19501 attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc gtattttaca
    19561 agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt aaaaagggat
    19621 tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc caaaaagtat
    19681 cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa aagctatcga
    19741 tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac gctatctgaa
    19801 attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca gaatgtgttc
    19861 ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt tcaatcgttg
    19921 acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc attgcttgct
    19981 gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa ataacgacag
    20041 gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct tgagataacg
    20101 tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga ataaagtgat
    20161 cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc attttcccgt
    20221 aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa accatcccaa
    20281 aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg aattcgatct
    20341 ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt tttcctgcac
    20401 cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg acttgattca
    20461 tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt tttcctttcg
    20521 gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca tctaatatct
    20581 caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca taagaagcgg
    20641 tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag aagccgatcg
    20701 tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg aaggcgagtt
    20761 gattaatgaa acgaatggcc ggatagatag caaagttcat aaattgagca cgtttaaaag
    20821 cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct tgctgattga
    20881 atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt aaaacaccca
    20941 gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta gttgtaacaa
    21001 ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg atataaaaca
    21061 gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg atacctgtca
    21121 ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg tcacctactt
    21181 gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt tcttttcgca
    21241 ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata aatgaagtga
    21301 tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat gcttgtttga
    21361 tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag agatcatcga
    21421 tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat aaactgcata
    21481 gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa cgtatcaaag
    21541 cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata ttccttgtga
    21601 ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag taccttgtcc
    21661 aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg tactgaggcg
    21721 ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg ctcttaatgc
    21781 tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga tctctgctgg
    21841 tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat aattagaacc
    21901 gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt cttctaattg
    21961 agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc ccatctgcaa
    22021 gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac tgatgtggga
    22081 gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta cttttcctat
    22141 cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag atccggtccc
    22201 gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt ctagaactgg
    22261 atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat ttgtctgatc
    22321 aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct ctgcttgcag
    22381 tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca ataccatagc
    22441 tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag tcacgacacc
    22501 gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag aagcataaac
    22561 gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt tcactttgat
    22621 catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat atgattgatt
    22681 atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga tggtgatccg
    22741 atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca gtcgataaac
    22801 aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata gagaataacg
    22861 aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca tttggcaaaa
    22921 taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca aaagagatcc
    22981 agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga aatatttctc
    23041 ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag aggcaactgc
    23101 agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt ttataactga
    23161 ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg gtacacctaa
    23221 tgtaccggcg atttgtaaac agatcatcac aaaggtaagg agagcgagtc ctttgttttt
    23281 ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat acttttcgat
    23341 tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa aaagaggtga
    23401 gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga tttgccaaaa
    23461 tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca agaagagaat
    23521 gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt tttttataga
    23581 aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt gacggagtta
    23641 tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt gatgaaacaa
    23701 aaacaaaaag agataaggga gcaaaaaaaa cagttgaaat tgatgatcga tacaaacgag
    23761 gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga gtttgaagat
    23821 attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat gagtatgcca
    23881 gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt acatttattt
    23941 actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt cttattgaaa
    24001 tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag aatgtatgaa
    24061 aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac ggatgaaaac
    24121 aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga aatatgtgtt
    24181 taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct ggttcgatta
    24241 cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt tttagaggaa
    24301 atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg taattgtcct
    24361 cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat ggtgaactga
    24421 gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat gagaatgata
    24481 aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac attattacaa
    24541 tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt aatcaaatag
    24601 tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt tttgcttata
    24661 aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag aaaaatcaca
    24721 aaggttattg ttatttttat atattctttt taagaatgat tattttttta tagaaatttt
    24781 aaaaaataaa acacgttatt gatggatagt tagtttgtta tttggtaata ttatagaagt
    24841 tgactggtag tgatttattt ttcgttgttt tataaaaatg ttattttttg gaaaaattca
    24901 caaatatgta acgaatgttt ttctggaatt tgctgtgtta aaaagcagta tgactaatat
    24961 aaatactatt gtcatttatg caatttttta tggatagtaa ttttagaggg gaatcaatga
    25021 aggaagaata gaagggaaaa atagttgcaa atacgccagt tagcaaaaat agcaatacat
    25081 cttcaagctt taaaattcga gagaatcatc ttggtagtgg aatcaactac aacaaaagga
    25141 ttaaaccaat taatagatag aattaccaat ggaaaaatag aaaaggtagt tattctatac
    25201 aaaagttgtt taattcgctt cggttatgaa cttagtgaaa ccctttgcaa tatatggtac
    25261 agaatataga aattattgac attacagaaa atgatgaaga tttaatacag attgtcacta
    25321 tttgtagata ccttttacaa ggaaaccgag ccaataaagc taagaagatg attaaggagt
    25381 tgatggaaga cgatacaagt taagaaagta aaactacgcc caaataaaga gcaaaaagag
    25441 taattggacg tggaaaatgc aagaaatgaa ccatcgattc ggtggacagt ttattagtaa
    25501 tgacggtttg agaacatcca tgacgagaat gaaggaacat cctaaatgcg tttagttgaa
    25561 ccaagtgcca aataatatgg ccaaataagc gatcagttat cgatgaatcc caagtattct
    25621 aaactatata ttcattttga tgctaagcat tgatatattt ttttgggatt gatgaaggtt
    25681 aaccaataca gggactcact gatgaaattc tagagtctga ccttggtatc aacgatttag
    25741 tgattgtttc taatggaaaa gtataaaagt atataagtac attaacaaaa taactattag
    25801 ggttacgctc cagcttgtgc aaggcactgg caggaggaat cgtgaaatca taattatggt
    25861 taagccacac ggacaactaa aagtcataca aagctatcga atcaatcaac agaagacaat
    25921 cggcaatcat tagctttgtt tacagcttac attgcaacgc ttgagttgaa ccgaaaatac
    25981 gagggaggta acgcagccat tttgagttgg ggaatctttt tagaaaatta tcgggtacct
    26041 tgttgtttag tcaaaattat aagggggagt aatagtgagg aacaaatttc ataaactgtt
    26101 aagtatgttt ctagttatgc ttattgtgat caatcaattt gggaacataa cggttctagc
    26161 tgagtcttta gcagaacagc cagagcgttc gctgacgatc gaagttgatc aagaggaggc
    26221 tgctttgggt gagcagttcc agttgcgagt cagaggaaca ccagacctgc taaatgcatt
    26281 ggtcattgat aagagtgagg atttgattga aggggaagtg aagcaactca atgattacga
    26341 acgtctgatt acttattctt cccagcattc aggtaaatac gaattgaccg caagaagcgg
    26401 tgatattcaa tcaaatacgg tctcaataga aatcagtgta ccagaagaaa gcacaagtga
    26461 gtcttttaat gtaccagaag aaagcacaag tgaatctttt aatataccag aagaaagctt
    26521 aagtgaatct tttaatgaag ccagatcatc tgagccatct ataacgcagg aatctcagat
    26581 tgaaagacaa gaggagctct tgaattatga catcggcatc tctgctgagc gccccacttt
    26641 gccgagcagg catacacaaa cgttaaaggg atacattcaa ggaggcgctg gcgatattct
    26701 tgaagaatat ggggagatgg tcgtacgagt tcctagagca tcgattggct taattgagtt
    26761 cattagagtg gaggtcgctg atgattcacc tttaaagcca ctggcatttt accaagaagg
    26821 cacagacgtt gtttttccat ttacctttga ttatgaagga ttaaatgaag ccgctcagtc
    26881 gtatacattc agtatcacgt ttgaagttgc tttctttcaa tcaggcggta ctgagccaaa
    26941 taatgacttt caagtgagtc ttacttatgc tgagcgagca gcaaacacgg aattttcaat
    27001 tacgcctatt ccttcatcaa gacccatttt ttcgaaatta tactatggct ctagagaaat
    27061 cgacagccaa ggaaatcttg ggaatctgct gattgacggg caagacgtga ccaacagtaa
    27121 taaatttatt ttgcaggtaa attatgaagg atcacgaaaa gacggtgtag tggttaccga
    27181 tgtactaccg caaggaacaa ctttggcacc gaatccgact acatggagtt ccactggaaa
    27241 tagagaacct atttcaggtg gggttcggat cgcagaagta acgaatccag gtgaagcaaa
    27301 cgttagaact cattatgttt ccgaggaatt tgtggacaaa gtatctttta ataaggaaac
    27361 gaatacactt gttgtggact ttggtaatct agcagagggt caatcgtatt ttattgaata
    27421 tgctcttgaa gtgaccgatg tcgacttgtt caatgaagga agacaagagg atgggttttc
    27481 tcggaatcga gcgagtatga cctacaataa tcaggtaatg agccgagact accgcttgag
    27541 aatccctgaa agtaatcttc cggcaatctc tttaagaaaa agtgtggaca aaaatgttat
    27601 caatctcaat gaaaatgaac taacgtatac tctgcatgtc tcgatgtttt ctggaacaag
    27661 caatacgctt gttattgaag atgttttgga agaaggcatg gaatttgtgt catttctatc
    27721 agatattccc tctttcattg atgccgaagt caataatgga atagttcgtt tcagtgcgaa
    27781 taatacgatt ggtggtccga caagttttac cctctctttt aaggtcaatg tagaggcgta
    27841 tgcggtcggc gatcaaattt taaactttgc aacgcttgtg aatagtgaca atcgattgaa
    27901 tacgagtact gtaagaacaa ggaaaatcga tgggcgtatt aaagtaatta aaactgatga
    27961 gaatggccaa aggctggcag gagcaaaatt tgaaatttta tcaagcgatt cacaagtgat
    28021 acaagaaggt ataacggcag aaaacggaga atttttaagt gaaccgcttc ctgtaggtag
    28081 ctatcaagtc cgagaaacag aagcaccgga agggtatctt ttagatgcga cggtacatga
    28141 tgtttttata aatgaatact ccatagaaga agtgacgtta accattgaaa acatccttga
    28201 tacgggtggt gttgaactaa ttaaacatgc tgaaggcagt ggtgaagtcc ttcaaggagc
    28261 tgtttttgag ttacagaacc gagaaggaga aacgctacaa accggt
//
LOCUS       DBBGRF010000036        27581 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000036 DBBGRF010000000
VERSION     DBBGRF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.036"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            590..1759
                     /locus_tag="ACIZD4_001791"
     CDS             590..1759
                     /locus_tag="ACIZD4_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HGC5990708.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            2232..2786
                     /locus_tag="ACIZD4_001792"
     CDS             2232..2786
                     /locus_tag="ACIZD4_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5990709.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(2959..3396)
                     /locus_tag="ACIZD4_001793"
     CDS             complement(2959..3396)
                     /locus_tag="ACIZD4_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5990710.1"
                     /translation="MFSSEENKPLYLDYVNHNLKIIIKENNLKHITLHGFRHTHCSLL
                     FESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFMSSTEEKQGSLQK
                     VKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            3444..4391
                     /locus_tag="ACIZD4_001794"
                     /pseudo
     CDS             3444..4391
                     /locus_tag="ACIZD4_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            4662..5097
                     /locus_tag="ACIZD4_001795"
                     /pseudo
     CDS             4662..5097
                     /locus_tag="ACIZD4_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            5113..5946
                     /locus_tag="ACIZD4_001796"
     CDS             5113..5946
                     /locus_tag="ACIZD4_001796"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5990711.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            6191..7216
                     /locus_tag="ACIZD4_001797"
     CDS             6191..7216
                     /locus_tag="ACIZD4_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5990712.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            7354..7479
                     /locus_tag="ACIZD4_001798"
     CDS             7354..7479
                     /locus_tag="ACIZD4_001798"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990713.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            7504..8619
                     /locus_tag="ACIZD4_001799"
                     /pseudo
     CDS             7504..8619
                     /locus_tag="ACIZD4_001799"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            8702..9598
                     /locus_tag="ACIZD4_001800"
                     /pseudo
     CDS             8702..9598
                     /locus_tag="ACIZD4_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            9614..10438
                     /locus_tag="ACIZD4_001801"
     CDS             9614..10438
                     /locus_tag="ACIZD4_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990714.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            10470..11780
                     /locus_tag="ACIZD4_001802"
     CDS             10470..11780
                     /locus_tag="ACIZD4_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HGC5990715.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            11928..13187
                     /locus_tag="ACIZD4_001803"
     CDS             11928..13187
                     /locus_tag="ACIZD4_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC5990716.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            13197..14069
                     /locus_tag="ACIZD4_001804"
     CDS             13197..14069
                     /locus_tag="ACIZD4_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990717.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            14081..14911
                     /locus_tag="ACIZD4_001805"
     CDS             14081..14911
                     /locus_tag="ACIZD4_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5990718.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            14951..17134
                     /locus_tag="ACIZD4_001806"
     CDS             14951..17134
                     /locus_tag="ACIZD4_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGC5990719.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            17195..18415
                     /locus_tag="ACIZD4_001807"
     CDS             17195..18415
                     /locus_tag="ACIZD4_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HGC5990720.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            18412..19872
                     /gene="gtfA"
                     /locus_tag="ACIZD4_001808"
     CDS             18412..19872
                     /gene="gtfA"
                     /locus_tag="ACIZD4_001808"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGC5990721.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            19949..21055
                     /locus_tag="ACIZD4_001809"
                     /pseudo
     CDS             19949..21055
                     /locus_tag="ACIZD4_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            21377..21586
                     /locus_tag="ACIZD4_001810"
     CDS             21377..21586
                     /locus_tag="ACIZD4_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGC5990722.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            21579..21728
                     /locus_tag="ACIZD4_001811"
     CDS             21579..21728
                     /locus_tag="ACIZD4_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HGC5990723.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            21882..22547
                     /locus_tag="ACIZD4_001812"
     CDS             21882..22547
                     /locus_tag="ACIZD4_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5990724.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(22831..23916)
                     /gene="xerS"
                     /locus_tag="ACIZD4_001813"
     CDS             complement(22831..23916)
                     /gene="xerS"
                     /locus_tag="ACIZD4_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGC5990725.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            24250..24483
                     /locus_tag="ACIZD4_001814"
     CDS             24250..24483
                     /locus_tag="ACIZD4_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HGC5990726.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            24480..24887
                     /locus_tag="ACIZD4_001815"
     CDS             24480..24887
                     /locus_tag="ACIZD4_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGC5990727.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(26024..26542)
                     /locus_tag="ACIZD4_001816"
     CDS             complement(26024..26542)
                     /locus_tag="ACIZD4_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGC5990728.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLSLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            26909..27157
                     /locus_tag="ACIZD4_001817"
     CDS             26909..27157
                     /locus_tag="ACIZD4_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990729.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
BASE COUNT         9458 a         4177 c         5072 g         8874 t
ORIGIN      
        1 tcttcctaaa ataagcgaat agcattccta aaacctataa aatttttaga tgaagcgaca
       61 agtggacaat taataaacta cttgaacatg aaattatgga tcacctttca aatttagaaa
      121 atggaattct tatacttatt gcgcaacatt tattgattgc aaaattatgt gacaaaaaaa
      181 actagtagaa gaaagaataa tggcttgata ataaagtact acctattaaa ggtagtactt
      241 tatttaattt agtataaatt aacatactac tatattttag gtttcatatt atataaatta
      301 ataatatact accatttgtt ggtagtataa tttaaaggta ataagttatt cttttattac
      361 tatgtttggg ttttatagca aagaaagttt aataagagtt tggacctagc aaacaatatt
      421 aatgaggtca ttaaatctta ttatctttag tgatataacg aaatatctac acagacaaaa
      481 tgatagcgta aaatattttg tgtaaataga tatttagggt agaaaaaaag aaagtccatt
      541 ctgtaaaatt aaagttacca caaccgaaat tttataggag gactttctca tgcccaattt
      601 tactacagaa attatggaaa cactaatcaa taaaggtgat ttagatgaat tatttcgatg
      661 tcatttagaa ttagctgtta attcattatt gcaggctgaa ttaacagctt ttcttgatta
      721 tgaaaaatat gatcgtgctg ggtttaattc aggtaattcc cgtaatggga attattcacg
      781 ttcattcaga acagagtatg gagaattaaa tttggtaatt cctagagata gaaatggtaa
      841 gttttctcaa caaactttac ctgcttataa aagaaccaat gactctttag aaaccactat
      901 tattcagcta tttcaaaaag gaattactat gtctgaaatc tctgaattga ttgaaaaaat
      961 gtacgggcat cactatacgc cacaaaccat ttcaaatatg actaaaatag tttctgaaga
     1021 tattattgcc tttaaagaaa ggtccttaga atccagatac tctgtcattt ttatggatgc
     1081 tactcacatt cctttaaaaa gacaaactgt ttcaaaagaa gcagtttata ttgtaattgg
     1141 cattcgatta gatggaacca aagaggttct tgggtttagt cttgctccaa ctgaatctgc
     1201 ttatgtttgg aaagagattc ttcaagacct aaaagaccgt ggtttaaaag aggttttatt
     1261 agtcgtaact gatggtttaa gtggcattaa cgatagtatt catagtgttt atccaaatgc
     1321 tcaatttcaa caatgttgtg tccatatatc tagaaatatc gctcataagg ttcgtgttag
     1381 tgatcgacaa gaaatctgta gcgatttcaa attagtttat caagcaagtt caaaagaaga
     1441 agcaaataat caaataaggt ttatgataga taaatggaaa aagcagtatc cacgagtggt
     1501 taaattgctc atgaatcctg ctatattaac cttttataat ttccctccgt caatcagaag
     1561 aactatttat tcaactaatt tgattgaagg ttttaacaaa caattaaaga aatataccaa
     1621 aagaaaagag caatttccta atgaagaatc tctggagaga tttctagtat ctcaattcaa
     1681 caactataat caaaagtttc tatgccgagt tcataaaggt tttaaagaaa tacatgatac
     1741 attagaatca atgttttaac ttgatcaaca gaatgggctt ttccatttac acaaaattat
     1801 tgacgctccc gacaaaatta tgatcttgcg taaagttata aaatattaat aaaaatattt
     1861 tattaatgaa aagcttggta gcacggttat tcatatgcta atttatttca ctttatagta
     1921 aggggagttc ttagtatatt gttcaaactt aaatttcata taatttaatt atgtaaatta
     1981 gctattctaa gaacttctac ggataactgc ccgtctaaaa tttaaataag agcttagaat
     2041 cttcatataa gtaaggttaa tttttttgta caaaaaagtc ggaatattct gagttactga
     2101 aatgatataa aatcataaac taaatccctt gattttattg actttcaaaa gtttatatat
     2161 ataagttaat gattatggta aaatatatac ataatcatta actcagaata tttttaagaa
     2221 gggaaacaat agtgagctat aatgtacaac cgttaaggac aaatgaagag atacaagatt
     2281 ttcagttttg gctaagaaga acaagtaatc cggaaagaga tagtttttta tttttgtttg
     2341 gaatcaataa tgggttacgt atgtcagata ttataggatt aaaagttgga gatatacgag
     2401 gcaaaagtaa gcctattatt gttgaacata aaacaggtaa gcgaaaaccg atttttatag
     2461 ataatttgag agaagaaatt ttattatata ctgaaggtaa agaagaaaat gattggttat
     2521 ttccgagtcg gcaacaaggt cgacatataa caagggatcg tgtctatcag atatatgcag
     2581 atatagcaga aaaattagga cgagatgata taggaacaca tacattaaga aaaacttttg
     2641 ggtatcacta ctacaagaaa actagagaca ttgctacctt aatgtttatt tttaatcata
     2701 gctcgcaagc aattacaaaa aggtacattg gtataactga agatgaaata ggagcatcac
     2761 ttcgtggatt taaactaggt gtataattta aaaattttta taaacagtaa agacaaagat
     2821 taaaagctat ttttatctag aacgatttta tttcataaag ttcgcggaat aaaagctggg
     2881 gttactggta cttggtatag gttcgtgtta tataaactaa gtaattaaat aacattttta
     2941 ggttggaaaa ggatgaaatt aaaaaaagag aatcaatacg gtctcaaaaa cgcaaacgct
     3001 gcggaataag aaaaatactg ataactcaac gtttagcaga ctatctaata gggatagtct
     3061 gcttttttcg tttttgacca tacttttgac cttctgcaaa cttccttgct tttcctctgt
     3121 agaactcatg aaatctgcaa aacgaattgc cgtttcctct gtctgctttt tcgcgatatg
     3181 ggtgtatata tcatccatag tggttttaat atctgtatgt ccaagtcgaa catacacttc
     3241 tttgacagac gcaccagatt caaagagcag actacaatgg gtatgacgaa aaccatgaag
     3301 tgtgatatgt tttaagttat tctctttaat gatgattttc aaattgtgat ttacatagtc
     3361 taaataaagg ggcttatttt cttctgatga aaacaaaagt tgttcaccat cttttatagg
     3421 tttgattctc atttttagat attatgcccg cacgtattca tcacatttct attgtgaatc
     3481 gctttattcg accgacattt gacttttatc ataatatact cggtttaaaa ttactaatga
     3541 aaacaattaa tcaagacgat cataccatgt atcacctgtt tttttcagat aatcaccacc
     3601 gtgtgggaac tgaactgact ttttttgaag tacaagaagg gaacaaccag ttttttggaa
     3661 ccaatacgat tgaacgaacg atactaaaag ttccttccga agcatcattg catttttggg
     3721 aaatatattt tgaaacacaa ggcgtttgcc attatggaat cgaatcattt tctggacgac
     3781 ctatcttacg ttttgaaggg ccagatgcaa cacgattagc tttagttccc ttacgcgaat
     3841 ttgaagatat tgatgattat ttcccgtatg tcacagacca gatccctaca gagcatgcca
     3901 ttttaggaat tgatgccatt caactacgcg tacaatattc cgatgcgact gaacgagagt
     3961 tattgtcggt aggctggtag cacaaagaat acgtcagttt cttttcgggt catcaacgag
     4021 tgacaatctt agaaaatcaa gacactcagt tctatcaaga agttcagatt attcaagatc
     4081 gtgagaatcc agttgccatt gaagggattg gtagcgtcca tcatgttgcg tttggcgtag
     4141 aaaataaatc tgatttacaa cgcatcgaca aacaattaca agagcgcaat tttataaatt
     4201 caggaataaa agatcgtgaa ttttttgtat cactttatta tcgtgaccca aatcaattat
     4261 tgattgaaat tgctacaggg gaaggaaacc tagatgcaaa agcgtatgaa aatcaaagtc
     4321 cacgctttga agaaattcct ttatttttac cgcagtactt aaatttcatt cgtgaacaag
     4381 tggagcaata attagctaat caaatccatg acgaagagta agaggttgac tcataagtca
     4441 aaaaataaag aaaaacgcat caaatccatt ctaaagaatg ttgatttgat gcggttccta
     4501 tttttataaa ctatcatttt cgactaataa aactacttat gagtcagcct ctcttttttt
     4561 cttgattttt atacctcttt ctaggtaaac taaacatctg ccaaaaatac cgtgtctcat
     4621 tgaaacattc tcaactattt caaaataaag gggagtacca aatgaacgag tatattgaaa
     4681 ttatccacgc aagagaaaca acttaaaaat gtcagtctca aaattcccaa aaataaaatt
     4741 agtattttta ccagcgtatc tggttcagga aaatcatcga ttgtttttga tactattacc
     4801 caagaagctg gtcgtcaact gaatgacacc tatgatagtt ttacccgttt atttttacct
     4861 aaatacagtc gtccagaggt tgatgagatt gataatcttt ctacggcgat tgtggtcaat
     4921 caaaagaaga ttggtggcag tgcgcgctca acgttaggga cgattactaa catcaatgcg
     4981 ttatttcgtg tgttgttttc atgttttgca acacctagtt taggatatgc aaatgcttat
     5041 tcatttaatg atcctagtgg aatgtgttct gtctgtcagg gaatcggtaa gacgattgca
     5101 tttttaatag gattgcttta tttttcggct attgataatg ctgattttgt attttctgat
     5161 ccatttaccg cagaagtttt gtctggaatt gaggaacagg caaagaatca tggttatttt
     5221 gtattggtgc ataatgttaa ttcagcagaa gatgttaaaa ctattcagag aaattggcgt
     5281 tttgaggggt tcattgttgt tggtgtacgt gtaaaagaat ttttggaatt aaataacgtt
     5341 tttgatggtc ctgttgttta tattgatacg catctttcaa aagagacatt aagagaactt
     5401 gaacaacaaa tgaatcgttt atttgtaaat acaaatgatt accaagctag tacattggca
     5461 gtggaacatt tgattcatta tggtcatgag aaaatagcgt ttctttcttt tgactacatt
     5521 gtaggtgaac caagtgttat tcaagaacga catcaagctt atatcgatac attaaagaaa
     5581 tatcatttaa cctttaaatc gcattggata tataacaact ctgaatttga gcgaatttat
     5641 caagaattag ctgaatttac tgcaattgtt gttactggag attatttagc ggctaaatta
     5701 gtaaaatttt taaaaaataa gaataaacga gtgatggaac aattatcgat tattggattt
     5761 gatgatatta cttttgcaga attaatggat cctgcgttga caacaatacg actaaatcca
     5821 ggtaacaagg gggcgattgc ttttcaccaa ctgattggac tggccaaaca agaagaaata
     5881 aaaaatcaag tactactatt agagggagaa ttgatttctc gagactctgt tcacaaaatc
     5941 aaataaaaaa gctctgtgaa ataagtatag ttaacaataa aatatccgaa cgatagagag
     6001 aatgaactgt gatctagcag ttcctcgtcg caaattcact agaattagca ttatttactc
     6061 taaattgttc ggatattttt tcttgttttt aattatgatt acagtgccta tttttaacga
     6121 aatttgctta ttttcaaaat gtatgattat atgttagtaa acactttcaa atatgaaaag
     6181 aggagctatt atggtaggaa ttagggatgt tgcaaaacgg gcgggtgtgt ccattgcaac
     6241 agtatcgcgc gtgctaaatg aggatccgac actttcagta accgatgaaa ccaaacgaaa
     6301 gattgcagaa tcggttaatt tttatcatta tgtcaaaaaa agtcccgttg caaaaaattt
     6361 aacaaatatt gcattaataa cgacagtttc tgaagtagat gagttggaag atccctattt
     6421 tcgaacgatt cgcagaggga ttcaagtcga agcagaacaa agcaaagtca atttgaagaa
     6481 aattattcgt ttgtcagaaa caccgttgga gcaagacgat ttgctaaaat gtcaaggtgt
     6541 gttgattatt gggcaggtgc tatcttctgt gattgaagaa gtatcagcaa ttaattcgaa
     6601 tgtcgtagtg attgatgacc ctagtattga agctgaagta gatgcagttt atactgattt
     6661 aacaaaagca acgaatcagc atttagatcg attgtataaa aaaggacacc gaaacattgc
     6721 gtttatcgga ggaggacgtg ttcgtttaga tagccaagga aataaacacg tgtcagatga
     6781 tgattatcga aaaatagcct atgagacgtg gatgaaacaa aaaggattag aaaaatatag
     6841 tcaaatttat ttagaaggct ggaccacact tgacggaatg caggcagcag atttactttt
     6901 gaaaaaacat gctaaagata agttgccgac tgctatcatg gtaggaaatg atcctattgc
     6961 tgtgggggtt tatcgttcac ttcaaaaaaa tggtctacat attccagaag atatttcgat
     7021 tgtgagtttt gataatattg aagttgctga atttttaaca cctgcattaa atacggtgaa
     7081 tgtgaataca gaagaaattg gaaaactagc agttcgcatg gttaatgaac gaataaaaga
     7141 agttagaaat gtttcgatca aagtgattgt ttctaataat attattgtta gagaaagtga
     7201 aaaaaatatc gattaaaaaa gtaaacatcc aaaaaagggt gtttactttt ttgtttacta
     7261 atatttttag taaaaaatct cgacaaaaca ttaagtaaac agttatggtg ttgttaacaa
     7321 aaagaaaacg cattcaaaac aggaggaatt aagatgaaac atttcaaaaa aatagcttta
     7381 acagggatag ctgttttaac tgggacatta ctcgcagcat gtggtggggg agatagtaat
     7441 tctaaagacg ggcaagtaac tttaagctat gcgagttgag atactgacca agctccagga
     7501 ctaagaaaaa tgttagatga atttgaaaaa caaaatcctg atatcaaagt agaaatggag
     7561 acaacgcctt gggatcaata ttgggttaaa ttagaagctg caacaacggg aggtaatatg
     7621 ccagatgtag taaccatgca ctctagcgaa tcctataaat atatgtcaca gaatgctttg
     7681 atgggacttg atgatgttat caaagaaaat gatattgaca tgggaaactt tactgaagga
     7741 attgctgatt tctatacgct tgaagacgaa ctatacgcaa tccctaaaga tgcttctgta
     7801 gtggggctat ggtacaacaa agaattattt gataatgcag gtgtcgatta tccagatgaa
     7861 acatggacat gggaaacact cagacaagct gcaattgatt taacagatga atcaaaaggc
     7921 atctatggtt ttgcatcaca tattggaaca gagactggct actggccatt tatttatcaa
     7981 aatgggggag aagtatttgc cgatgacaat acaaaatcag gtttgaatac cccagaagca
     8041 caagaagctt tagcttttta tcgagatatt gcacttgttg atcatgcttc accaacaatt
     8101 acagaattac aagatcctga taagttaagt cgttttcaat caggtagatt agcaatgatg
     8161 attgaaggaa actggtttgc accgggattt ttgaaaaatg actatctagt tgaaaatgtt
     8221 gcttctgccg tgttacctaa gggaaaagtt aatgcaacaa ttacaaatgg acttggttgg
     8281 gctgccagtg cgagtacaaa atacccagaa gaagtgaaaa aactaatggc atttttagct
     8341 agtgaggacg ccaataaaat ccaagcggaa acgggggcat caatcccagc actaaaaggc
     8401 tttgaagacg agtgggctgc ttcttcagat acaattgatt tgagtgcttt tggaaaaatg
     8461 ttggagtatg gagtccctcg tccatacaat aaagatggat tacgagctga acaagcagaa
     8521 gttcaaatta ttaaccgtat tctgtctggt gaagtaactg ttgaagatgg aaccgctcaa
     8581 attgaaaaag aagtcaatgc gatattgagc ggaaattaaa ttagttaatt atacaatata
     8641 caggcgaaag gattctattt cgtctgtata ttaatggatg aataccaaaa agggggatat
     8701 tatgaaaaat cgaatttttg gaaaatatcg taaagatcaa gtgatatggg gctatatttt
     8761 tatttttcca acggcattag gattaatttt attaaatata tggccagcaa ttcaaacagc
     8821 aattttaagt tttcaaaaaa cggtagggtt cggtgatact gaatgggtcg gattaagaaa
     8881 ttaccaaaaa atgtttgcag acggtgaagt ttttcagtct ttattaaaca cattaattta
     8941 tgcagtggtt tcgataccta gtattgttgt attatccttg ttggtggcag ttttaatgaa
     9001 tagaaaagtt aaaggattgt cgatttatcg gacaatttat tttctaccag tcgttgctgc
     9061 accatccgca gtcgcaatga tttggcgctg gatgttcaat aatgattatg gactgattaa
     9121 taacatgttg gctaaaatag gtctcgatgg accagcatgg ttaacggatc catcgattgc
     9181 gatttattct attatcattg taggagtttg gagtgctatt ggttataaca tggtgttatt
     9241 actagccggc ttataagaaa ttcctaaaga ttattatgaa gcagcggaaa ttgatggtgc
     9301 tagtccaatc cagcagtttt tcaacattac gttaccatta gttacaccaa cattattttt
     9361 tgtagttgta acaacagtta tcaatgcttt ccaagtattt gatgttattt ttatgatgat
     9421 tactcctaat agtaccgcca tgtttaaatc acaatcatta gcctatttat tctataaaca
     9481 ttcatttatt ttaaatgaca agggatatgg ttcggcaatc gttatgttcc ttttagtgat
     9541 tatattaatt attactgcaa ttcaaatgaa gttgcagaaa aagtgggtaa actattaagg
     9601 aggctatcaa attatgaaaa ataaattttt ttcaaatgcg ccaatccata tcatgcttat
     9661 tttaggtggt attgcaatgg cattaccttt tatttggatg attttaactt cagggaaaac
     9721 gttggttgaa tctacccaaa ttccacctac aattttccct gagaaatttc agctaagtaa
     9781 ctatcaacaa gtacttgatt tattaccatt catggctttt tatatcaata catttttaat
     9841 ggttgttgga cgagtgattg gctcggtttt attttcagca atggctgcat atgcttgtgc
     9901 gcgtctaagt tttccaggga aaaatatcct tttcagctta gtacttattc aaatgatgat
     9961 tcccggttcc atttttatta ctccacagta tttattagca caaaaattgg gtattttaaa
    10021 tacaattcca gcattaatat taccaggggt agttagtgcg tttggtacgt ttttattaag
    10081 acaatttttc ttaggtttac ctgatgaatt ggaggaagcg gcctatttag aaggtgccaa
    10141 tatttggacg atctttttca aaattatgtt gccgcttgct aaatcaggat tggttgcact
    10201 tggaatattc acagcgttgt ttgcatttaa agatttaatg tggccattga ttgtcaatac
    10261 ttcaattgat aagatgcctt tagctccggg attagcaaac ttacaaggac aatatgccac
    10321 gaacttccca caattaatgg caggttcgtt attagcaatt tggccaatag ttgtgatatt
    10381 catcgttttc caaagaaaat tcattgaagg aattgctaca acaggtagta aattataaaa
    10441 ctattaatta gtgattggag agtaagtaca tgacaaaaat tacatttatt ggtgcaggaa
    10501 gtactatttt tgcaaaaaac gtattaggcg atgcgatgtt aactccaagt ctacaagatg
    10561 cacatattgc attgtacgat attgatgaaa aacgactaaa agaatcaaat ttaatgctta
    10621 aaaatattaa taaaaattcg aatgaaaatc gtgctgatat tgtttcttat tatgatcgca
    10681 aagaagcgtt aagagaggct gattttgtta tcaatgctat tcaagtgggt ggttataaac
    10741 cttcaacagt gattgatttt gatattccta aaaaatatgg gttgcgacaa actattggtg
    10801 acaccatggg gattggtggg atttttagaa ccctacggac actaccagta atgttagact
    10861 ttgctaaaga aatggaagaa gtttgtccaa atgcttggtt attgaactat acaaatccga
    10921 tggcgatgtt aaccatgggt gttttaaaag cgacgagtat taagactgtt ggtttatgtc
    10981 atagcgttca agtatgcgta ccagaattgt ttgagcattt aggaatagcc gatcaatatg
    11041 acttaaatga ctttcaatgg aaaattgcag gcattaatca tatggcattc ttgttggaaa
    11101 ttacaaaaaa tggggaagat ttctatccaa caattcgtca gttagctgca gaaaaaccaa
    11161 atccacatcc agattctgta cgttttgaat tgttgaaacg ttttggttac tatattacag
    11221 aatcaagtga acacaatgca gaataccatc catactttat taaatcaaaa tacccagaat
    11281 tgattgacga attagggatt ccgttggatg aatacttacg tcgttgtgaa caacaaatta
    11341 atgattggga aagcatgcga gaggacattg taaataatgg ggagttaaca catacgagaa
    11401 gccgtgaata tgcttcatat atcatggatt ctattacgac aggaactccg tcagtgattg
    11461 caggaaatgt cttaaataaa ggcttaatca caaacttacc gacagatgtt tgtgtggaag
    11521 taccttgttt agtcgataaa aatggcgtgc aaccaaccta tgtcggtgaa ttgccaacac
    11581 aattagctgc tttaaatcgg acgaatatca atgttcaaga actgacagta gaagccgctt
    11641 taacactaga taaatcaaaa atttatcaag cagcgtattt agatccacat ctatcatctg
    11701 aattgtcttt aacagatatc aaaaatttag tggatgattt aatcgaagca catggggact
    11761 atttacctga atataattaa aaagaagctg aaagagtaag gaattttcaa ttccttactc
    11821 ttttcttagt taaatttagt aaaaatattg acaaaacact tagtaaacag ttacattagt
    11881 gttaacaaaa agaaaacgca ttcaaattgt ataaggagga gcataaaatg aagtggtcta
    11941 aaaaaattat tttagcttgt atagcactag gagcaacgat ctctttgact gcttgtggaa
    12001 aaaatcagga agatgcaagc ggtaaggtag aaatagagtt ttttaatcaa aaaaaagaaa
    12061 tgactcaaac gattcaggag attgctaaag attttgaagc aaaaaaccct gatattcatg
    12121 taaaagttgt ggatgtaccg aatgctggtg aagtaattaa aacacgtatg cttgcaggcg
    12181 atgtaccaga tgtcattaat ctttatcctc aaagtataga attgaaagaa tgggcgaaag
    12241 ctggttattt agaggactta accgaagaac cgtatttaga gaatatcaaa aatggatatg
    12301 cacaacgttt tgctattgag gatcgtgtat atagcatacc attaaccgct aatgtctatg
    12361 gtttttacta taacaaaact gcttttgagg aaatggggat tcaagcacca gaaacttggg
    12421 cagaatttga aaaaatagta gctgagatta aagatcaaaa caaagtaccg tttgcgattg
    12481 caggagcaga aggctggact ttaaatggtt atcaccaact agctatagcg actgctgctg
    12541 gtggtgaaga ggaagcgaac aatgtttggc gtttctcaga agttaatgga attaatgctg
    12601 aaagcaaaga aatgcaaaaa gattttaatc gattagattt gttaagagaa ccaaaagctt
    12661 tgcaaaacaa ctggcaaggt gccggttata acgatacagt agttactttt acaaaaggtg
    12721 atgcgttgat tatgccgaat ggttcatggg caatgccgat gattcattca caaaatccag
    12781 attttgaagt aggaactttt ccttttccag cagatgaagc aggtcaaagt ctaacgattg
    12841 gcgcaggaga cctagcctta tcagtttctg caacttctca acataaagaa gaagccaaac
    12901 gttttgtaga atatatgaca acacctgaag cgatgcagaa atattatgat gtagatggtg
    12961 caccgtgtgc tgttgagggc gttatcgaga atactcagga ttcaccatta agtggtttaa
    13021 ctgaacttgc ttttactgat cgtcatttag tttggttagc caaagattgg aatagtgaaa
    13081 atgattttta taccttaaca acaaattatt tacacaatgg caatcaaaaa gccatgatta
    13141 acgcattaaa tgctttcttt aatccaatga aagctgacgg aaggtaggaa aataaaatga
    13201 aaataaaaga aattttaaat cgttactggg caatcatttt tgtagcaatt ccaattattt
    13261 tgcagatgat ttttttctac tttccaatgg ttcaaggtgc tttttacagt ttaactaatt
    13321 ggactggtct gacttataat tttgattttg tgggtttgaa caattataag attctttttt
    13381 ctgatccgaa gtttatcaaa tcgattggct tcactttaat tgtgacgctt tgcatgattg
    13441 ctggacaaat tggttttggt attttgattg cgcgggcgtt gaacgcaaat attaaaggga
    13501 aaacattctt tagagcatgg ttcttttttc cagcggtctt atcgggcgtg gttgtttctt
    13561 tagtatttaa acaaattttt aactatggtt taccaaaaat tggtagtatg ttaggcattg
    13621 aatttttaca aaccagtctt ttaggaacaa catggggagc gatttttgca gtaatttttg
    13681 ttttactttg gcaaggaatt gccatgccag tcatcatttt cttagcgggt tttcaaagta
    13741 ttccacaaga aattattgaa gctgctagaa tggatggggc gaatgataag caaatttttt
    13801 ggaatattga aatcacctac ttattaccaa gtatttcaat ggtatttatt atggcattaa
    13861 aaggtggctt aacagcattt gatcaaattt ttgctttaac tggtggtgga ccaagcgatg
    13921 ccacaacatc tttggggtta cttgtttata attatgcttt taaaaacaat cagtttggtt
    13981 atgcgaatgc tattgcttta gtcttattta tcttaattgg gattgtttca ctggcacaat
    14041 taaaattatc gaaaaaattt gaaatctagg aggtttccca atgaaaacat caaaagaaaa
    14101 aaatatttct aaatacttgc ttttattatt agggggcttc atgattttag ttcccttagt
    14161 ttcaacgcta ttcggttcat ttaaaacaac acccgatatt atgaataatt tctttcgttt
    14221 tcctaatcca gcgactttgg aaaatttccg aagattgtta gcggatggaa ttggtcatta
    14281 cttttggaat tcggcaatca tcacaatcat tgcagtagtt gctgtgacag caattattcc
    14341 tatggctgct tattcactag caagaaaaat gactcgtggg aaagcatacg gattgatgta
    14401 tttattttta attttaggaa tttttgttcc tttccaagta attatgattc cgattaccgt
    14461 tatgatgagt aaaattggtt tagcaaatat gtggggatta atcttactct atctcactta
    14521 tgccgtacca cagacactat ttttatatgt tggttttatt aaactaaatg tgcctatcag
    14581 tctggatgag gctgctgaaa ttgatggggc tagtcacttt acaacttatt tcaaaattgt
    14641 tttcccaatg ttaaaaccaa tgcatgcgac gactattatt cttaatgctc tatggttttg
    14701 gaatgatttc atgctaccat tattaatttt aaatcgtgat tctaatatgt ggacactacc
    14761 attgtttcaa tataattata cgggacaata ttttaacgac tatggtccaa gttttgcttc
    14821 ctatacagta ggaattgtca cgattacact agtttatctt gctttccaaa gaagtattat
    14881 agctggaatg agcaatggag cagtgaaata accaataaat tattctcatt ataaaggagt
    14941 tcataaactt atgattatat ttgacaatca cacacaaaca tttcatttac aaaataaaaa
    15001 aattagctat ctattaggaa tcgaagaaaa taattattta acgcatcttt attttggaaa
    15061 aaagattacg cactattctg gtgggtatcg ctacccccga acagatcgtt ccttctcacc
    15121 caacaatgca aatgcgcaag atcgtttatt atctttagac acattaccat tagaatttcc
    15181 aggatatgga catggtgatt ttagagaacc ggcgcataat attaaattag gaaacggtag
    15241 tcgtgtaaat gattttcgtt atgatagcta cgaaattcaa aaaggaaagc ccagcttagc
    15301 gggattgcca gccttatata cggaagatga tgatgaagct gaaacgctga ttattcaatt
    15361 gaaagacgcg attagtggat tgactttaca gttgttctac acaatttatc aaaatcacag
    15421 tgtaattatt cgttctacgc aattagtaaa taatagtgat gaaacagtgg agattaaccg
    15481 cttagctagt caatcaattg attttccaaa tcgtccactc gagttaattc atttaaatgg
    15541 tacctgggca agagaacgtc aaatgactag agaaaaaatt catacaggga taaaagtatt
    15601 agatagtaaa cgcggatcaa gcagccatca acaaaatccg tttgttgctt tagtagatgc
    15661 caaaacagat gaatttcaag gagaggcata tggatttaat ttagtttata gcggtaatca
    15721 cgaaacggtg attcaaaaag atccatttga ccaaacacgg gtcattatgg gaattaattc
    15781 atttaatttt ggttggcaac taaaaactgg cgactcattt caaacgccag aagtcgtgat
    15841 ggtttatagt aatgaaggtc tgaatacgtt atcacagacg tatcatgaat tgtataatca
    15901 ccgtttaatt cgtggaaact atcgtttaaa agaacgtccc acgttaatca acaactggga
    15961 agcaacgtat tttgatttta acgaagaaaa aatcatgaat attgtcgatg atgcgaagaa
    16021 cttgggcatt gaaatgtttg ttttagatga tggttggttt ggcggtcgtg aaaatgactt
    16081 cacttcatta ggtgattggg ttgaaacaga aggcaaactt gcttgtggtt tggaaaattt
    16141 agccaagcaa gtgcatgata acgggatgaa atttgggatt tggtttgaac cggaaatgat
    16201 ttctgaagat agtgaactat ttcgagcaca tccagattgg gcattgggta ttccaggtcg
    16261 tgaccgctca attagtcgaa atcaatatgt tcttgatttt tcaagacaag atgttcgtga
    16321 taatatctat caacaaatga cggcgatttt tgatcgtgta ccgattgatt atgtgaagtg
    16381 ggatatgaat cgaaatatga cagaagtcta ttctgtcttg ttggactcaa cgatgcaagg
    16441 tgaagtggct catcgttata tgttagggtt atatgaattt ttagaaaagt taacaacgaa
    16501 ttatccaact attttatttg aaagttgttc gggtggaggc ggtcgttttg atgcaggttt
    16561 cttgtattac atgccacaaa cttggacgag cgacaatacc gatgccgtgg ctcgtctgaa
    16621 aattcaatat ggaaccagct tagtgtatcc aatttcaagt atgggtgcgc atgtttcagc
    16681 agtcccaaat catcaaacag gaagagaaac gagtttaact attcgtggca atgctgcgat
    16741 ggctggtgtt tttggttatg agctagatct aacgcaatta acttctgaag aaaaagcaga
    16801 aattaaagaa caagttgcct tttataaaaa gcatcgccaa cttttgcaat atggaacttt
    16861 ttatcgcttg gaaagtccgt ttgaaggcaa tgatactgca tggatgtttg tctcaaaaga
    16921 ccaaacagaa gccatggtct tttatttccg agtattagca gaagctgcgc atccattagt
    16981 cacattgaaa ttagcaggat tagcagaaga agcaacttat caaatggaag atgtaacatt
    17041 tgctggcgat gaattgatga atctcggttt ttatattgac tcagaactac atggtgatta
    17101 tgcgacacaa cgcttttatt tgaaacagat atagtagctt gaatttacaa tataagtgca
    17161 acaccaaaag agactcattc caaacgaaga aaatatgttt tatttacacg catttactaa
    17221 aaagcagcct gatttgaatt gggaaaatga agaagtacgt gaagaaatct atgcaatgat
    17281 taactattgg ttagataaag gactaggcgg atttagaatc gatgcgatat taaacatcaa
    17341 aaaaaaacta gagtatggca tctttgaatc tgatggagaa gatgggttag ccttcattgg
    17401 gccctggatt cttaatcagt cgggcattga agtgtggtta aaagaaatga gagagcggac
    17461 atttaaacca cataatagta tgacggtagc agaagccgat gttcctaatg aacgtttaga
    17521 tgaatatatt ggtgaagatg gctattattc gatggttttt gattttagtt atacggatat
    17581 tgatgtacct gaaactggtg aatggtttaa agatagccaa tggacatgga cggatatgcg
    17641 taccaatatt tttacgaatc aattagttac gcaagataaa ggttggggcg ccttatattt
    17701 agaaaaccac gatcaaccac gttcaattaa taaatatatt ccagaagaat ggatcaatga
    17761 ttatagtaaa aaaatgttgg cgacgctttt tatgttacta agaggtaccc cttttattta
    17821 tcaaggacaa gaactaggaa tgaccaacat agaaatggca tcattagaag attttgatga
    17881 tgtagctacg cattctcagt ataaacgggc attagaatat ggattggcac cagagcaagc
    17941 attgaaagct gtcaataaac gaagtcggga taattctcgc acacctatgc aatggaatac
    18001 gcaaaaaaat gccagattct caacttctga taatgtatgg ttaaaagtaa atcctaatta
    18061 tccagaactc aatgcagaag ctcagttaac caatcaacag tcggtattca attattatca
    18121 tcaattaatt aaattaagaa aaaatagtgt atacaaagac gtgctaatct acggacaatt
    18181 tctaccagtg aaagataaaa atgaacatat tttgctttat gaacgccaat tagaagataa
    18241 aatcgtatta gttatcttaa acgttacagc aacagaacaa gaatattatg tagatgaaca
    18301 gtaccaacaa gtattaatca ataattatga agatgtttta ttagatcaaa gtcgaaaatt
    18361 gcgtttacga ccgtttgaaa gtattgtatt agctaattat ggaggacaat tatgaaaatt
    18421 aaaaacgaag caatgctcat cacctatgca gatagtttag gaaaaaacat gggcgaatta
    18481 aaacaagtct tagacaaaca tttacaaggt gttattggtg gtgtacatct gttgcctttt
    18541 tttccatcga caggtgatcg aggctttgcg ccgagtgatt atacgacagt tgatccagct
    18601 cttggaacat gggaagatgt ggaagcatta ggtgaagatt attatttgat gtttgatttt
    18661 atgattaatc acatttctcg tgaatcaaaa tttttccaag atttcaaaaa aaaccatgag
    18721 cagtcaccat acaaagaaat gtttatccgt attcatgaat ttttcccaga aaatcgacca
    18781 acacaagaag atattgattt aatctacaag cgtaaagaca aagcgccgtt tcaaacggta
    18841 gaatttgcgg atggtacgac agaagaggtt tggaatacct ttggggaaga acaaattgat
    18901 ttagatgtga ccaaagaagt tgtgaaagaa tttattcgag aaaccatcaa agatatggcg
    18961 aaccatggct gttctttaat tcgattagat gcgtttgctt atgcgattaa aaaattagat
    19021 accaatgatt tcttcgtgga accagatatt tgggaacttt tagacgaagt gcgtcaagaa
    19081 gcagcgaaat atgacgtcga attattacca gaaatccatg agcattattc cattcaaatg
    19141 aaaattgcca atcatgatta ttatatctat gacttcgcct tgccaatggt cactctgtat
    19201 tcactttata gtggaaaatc agaacgttta gccaattggt tgaaaatgag tccgatgaag
    19261 cagtttacaa cattggatac gcatgatgga attggtgttg tggacgctcg tgatttatta
    19321 acagatgaag aattggatta cacctctgag gaattgtata aagtcggggc gaatgtgaag
    19381 aaggtctatt caagtgccaa ttacaataat ttagatattt atcaaattaa cagcacctat
    19441 tatagtgcat taggcgataa tgaccgtagc tatctgttag cacgtgcgat tcaagtattt
    19501 gcgccaggga ttccacaaat ttattacgtt gggttattag caggaaaaaa tgatattgaa
    19561 ctgttggaag caacgaaaga agggcgtaat attaatcgtc attactatga tttagccgaa
    19621 attgaagaag aagtgcaacg gccagtgatt caacaattat ttgcactttt aaaatttaga
    19681 aatgaatctg cggcgtttga tttggatgga acgattgaag tagcaacgcc atcagaatca
    19741 gaaatagtga ttacacgtaa aaataaaaac ggtagtgata gtgcaacatt aacggctaac
    19801 ttggatacga aagaatttat cattgagtct aaagatataa aaattttcac tagtgttgca
    19861 ttaaaatttt aacctattcc atagaacaaa aaatccttta tactagcact tggatgactt
    19921 atccaagacc aataaaaagg actcatacat ggataagtat aaaacaaata cagcatttaa
    19981 taaatggttt tctgccataa aattaggaaa actttctgtc aactcccaaa aatgtatttt
    20041 tgattacaat tcgtatcgta aaaaactgtc ttttgaagct gtgctcaagc tctttctcta
    20101 cgcagttaat gaagaaaaag aaagtttgcg tgatttgagt acagctctta tcgaccgatc
    20161 gctccaacta gaaaccgatg tgtcatcgat tagtcatacc caattgtctc gagcatttaa
    20221 tgcacttgaa cctaaagtgt tagaagaaat ttttcaacaa ctgttagaaa aagttcaaca
    20281 tcaaatcaaa ccaaccaagc gaaatcatct gtatctgatt gattccagta cgttttcgct
    20341 tagtttaaaa cgtcataagt gggcgacttt ccgtcaaaca aaatcaggtg tcaagttaca
    20401 cttaaactat tgttatatgg acgatactac gatgtatcca actgatttta ccttaacaaa
    20461 tgcccatgaa catgatctca atcaactacc agtattggtg aatcaaccag aggcaactta
    20521 cgtgtttgat cgtgggtatt aggactttga aaagatggat cagatgcatt gggatggcta
    20581 tttcttcgtc actcggatta aaaaaaacac caaagttcac gtgatagata ctctggaaac
    20641 atcgccagaa acagaaattc tacgagacga gctggttcgt ttaggatcta aaacctatct
    20701 aaccgccaat ttccgactag tcactgttca agataagaac ggacgtgtgt ttcaatttat
    20761 caccaatcga atggacgtct cttcaaaaga aatctctgat atgtatcacg ctcgttggca
    20821 aatcgaattg tttttcaagc acatcaaaca acacatgacc attaaaacct tcttttctca
    20881 aagtgaaaaa ggcgtgcaga atcaattgat tttaacgatg atttccgctc tcctcacgtt
    20941 tctcatcaaa ttggagacga aaacggaaaa atcagtgttc caaatcaaac gattctttcg
    21001 ttatttactg tttcagccct ttgaatgttg tctagaaaaa ttaattccca catgagaaaa
    21061 aagaaatttg gctcgttact tttggttttc agttgaataa cagataaaaa attttctgga
    21121 aaaagtcatc ctctgcgtca gcacagtttt ttttgactta ttttcagagg aaatagtttt
    21181 cagaatattc taaaatgttt tatgcaacac tagtgatatt ttttagaatt agatttctaa
    21241 tgtgcatttt ttgagtatta aggagcaagt atacaaagat ttataaagct gattaaattt
    21301 gaataaaaat atgcaggaac gctactattt ttagtagtgt tcttttttat atttgaataa
    21361 aaaatgtggt ggttaaatgg tggttataac aaaaaatgaa ttaatgaaat taggttatgg
    21421 gaagtatcag tctgagagaa tcatacgaca ggcaaaagca attatggttt caaaaagcta
    21481 tacctattac gaaaatagaa gattaggact agtacctgtt gaatctgtag aagaagtttt
    21541 aggtatgaag atagaggtag aggaggattt tcagaatcat ggttaatttt aaaaaagata
    21601 aaaatgggaa atatcatttt actgctagtt tgggattcga caaacgaaca gggaaaagag
    21661 tacaaaaaaa cgtagagggg ttaaaacagt taaagaagaa aaaaagcgta taccgaactt
    21721 gtttctaatt atggaaaaga agcagaaact tctcaaagta ctatgttgtt tgaggagttt
    21781 ttttataaat tattcctacc ttattatcaa gggaaagtag aagaaagaac atataaaaat
    21841 cggttatcta caatcaaaaa aacttttctt atttctttaa aatggagtta agagaaatac
    21901 gtccaattga cattcaaaag tggcaaaata atttattgag caaatataaa aattcttatg
    21961 taagaaacat gtatgggatt tttcagatgt cattagatcg agcagttgtt ttgggactac
    22021 ttgaaaaaaa tcctgcaaaa gttattggaa atgtgaagaa aaggaaaact acagttgatt
    22081 tttggacaaa agaagaattt acaaaagtta tttcaacttt ttatattgat gatttgtacc
    22141 aacattttgg ttttatttgt atgtggttac tttttatgac cgttatgcgt ttgggagaag
    22201 ccactgcatt aacttggaaa gatattgatt ttgaaaataa aaacttgcgt gtgaataaaa
    22261 cactctatta taagagagcc aaaacctatg agtttgtaga acccgaaacg gcttctagta
    22321 ttcgtacaat cgaactagac gacaatacaa ttaccttttt aaaagcttgg aaggagcgtc
    22381 aagtttcaat aggaggcatg tcgtttgtac tttcttataa tggaacacct actcagaaat
    22441 atacaatccg tcatattatg agaagacatg caacgatcgt tggtgttcat ataatccgca
    22501 tacacggatt aaggcatagt catgcttctt tgcttatatc acaataaaaa gatgcacttc
    22561 gaattaaaga aaggttaaaa catgctgatg tacaaacgac tttaggaact tatggtcatt
    22621 tgtatctaaa ttcattgaga gagataacaa atgatcccac agattatatc caaactaatt
    22681 tttctaaaat caaaccgaca cctatttacg ataataaaaa ataaatgata aacaaaagta
    22741 ggatcacacc aaaagaaaca cactagaaaa actataatac aggcttttct agcgtgttgt
    22801 ttcttatttc cgcctattta tacattatac tcataaagca tttaatgcat cgatcgtagc
    22861 cgcattgtct atatgggtat ataaagttgt tgtattggta cttgaatgtc ccaattgttg
    22921 ggcagttaat accaatgaat ttgtctgttg gtagagtcta gtagctaatg tatgacgcag
    22981 tttgtgaggg ctgacttgaa ttctaaagcc ttttgaatat tttgctacca tccgttcgat
    23041 tgcaataccg gatatacgct tggcttctcc ttggtaaatt gctagaaata aagctttttc
    23101 gttttctgtt actttatatc gttctttccg aatagctaga taattagcta aatattccat
    23161 tgcgaatgct gctatattga cagcatctct tttatttcct tttctagtta ctaccacatt
    23221 attcttatct aaagataggt catctaaatt aatatttata acctcggaga gtctcaatcc
    23281 agatcctaaa atcagtgcat tgatcgccag gtctctttct acatctcgtt gataatagat
    23341 caaagctcgt ttactcaaag tatttttata ttcattggca atataatcta gataattttg
    23401 tgtatcctta tctagaaata attttttctc aatggcattg gcacgtgcag ctaacgtagt
    23461 tttatctgtg atggttgcta cttgatccat aggattattg tctaagtatg gttttcctag
    23521 aggattattg gaacttttcg aaagatattt aaatagaacc tttaatgccg tgatatttct
    23581 attgatagta gaagtagata gacctaagtt attattatct ttgagcttag tttttgttgt
    23641 ctcttttttt acattttctt ttgtgcgacg tttcaaatga gatttgtaca agtttaggtc
    23701 ataggcagtt aactgtctta tcgaggtgat agaagtatca ggaacgatag actcactcag
    23761 aagccattca taaaagagct tataattttt tagatattct aaagtggttc gaggtgattg
    23821 atctttatcc tcacgatctt gaacaaaatc ttttatataa tcgggcatat gaagtatgat
    23881 tgtatctatt ttttgatata tttctgtatt tttcatgtca ttcatccttt caataagtag
    23941 gggagaagag tatctctata attggactat accaattata gaatgttttg tcaattggta
    24001 tgctctaaaa tttattaatt tgtttcaaaa aaagcatata aacaggtata cgtttaataa
    24061 tttaaaataa atggtataca taaataggga aggaaataga agggagcaat ctaaattttt
    24121 tgaattttct taattaatta tatagaaaga acaatctttc tatagagtta gacatgagag
    24181 ggactatgct tgatttaaaa tcaacaagcg tatatactgt atatacaaag aaaaaggagg
    24241 gagaagacta tggcaattaa agaaagaaaa tttagggaag tggggaactc agtagtatta
    24301 actatttcaa aggagtttct taaagaaaat gggttaaatc ccggagatac ggttttttta
    24361 gatgaagaaa aacttcgagc ggcaattaca aaaaaacaag ccttatctga tgaaattgat
    24421 ttagcaatat ctcaagcatt aactgaatat gatactactt ttagagagct tgtcgataaa
    24481 tgagtattca ttacctagaa gccaaagata ttataaaaat gaatgtaatc caaataaaaa
    24541 aatactctcc taatgaaccc cttggtgtaa aggatgcgaa tgctttagaa atgtgtgtag
    24601 ggcaacttcg agcctcagct tttggtgaag aggtttatcc ttcgatttat gaaaaagcag
    24661 ctatcctact tatacaattg ataaagaaac atccttttca caatgcaaat aaacgtactg
    24721 ctttcttagc tacttttgtc tttttgaaaa tcaatggaca gcttttagct attgatcaaa
    24781 aagatgctgt aaatttagcg gtatatattg ctacgtatga taaggatttc gatcaactaa
    24841 aatatgaagt gatcaacact ataaagacac atacgcagcc catttaagga gttactgtat
    24901 gtgtctttat agggttatta gctgctatag cgaaataatt gaagtaaatt acaaatagct
    24961 ataattcaaa tccaactata tagaaaacgt aaattttcta tatagttgga ttaagataac
    25021 gactatttat tttatcatat ttttactata ccctatactt ttacttggta tatttatgaa
    25081 taatcgcaaa tttaccccta tactactagt ttgtaagtta gattaataaa aatactaaag
    25141 ttatttgttc ttttattaaa tacacctaca acttataaat tgatggtatt tagataacac
    25201 gaaagaataa aaataacagc tgatagtaaa gtttgttgac gattgctact caatcgaaag
    25261 tgagttagtg cgtatgaact tgcttctgaa aacttatgaa atgaaagacc ttttacatct
    25321 tgcagaaatc gttactggga ttaaactaag caataaaaac taatgttccc ctcattcttt
    25381 gaacttctac tatttgattt atttattctg ataaatgacg atttcacctt caggatcttc
    25441 aaatcccgta tagaatttat ttaagatctc ttcagtatca gtaataggat aggcgatagg
    25501 ccacataccc tttgatggtt agaataaact gctcaaaatc tgtatcgtat gttggcttta
    25561 gcatattaac aaaggctatc tccaaattat aaaccataag cgttgaatcg ttcttaacaa
    25621 tttcaattct tcctaaccca aagtcagaag atataattac cggacttgcc ttacccttca
    25681 tgtgggttgt tgagattcca tatttaaagg gaattgtcgg tactatcggc ggtctgaaaa
    25741 acatcccaaa aataaaaaaa tctttcccct gctagtctcc taagtccctt tgtagcggat
    25801 atggcaccat aatctcattt tatcgaagtg agtcatggtt tatctgttgg ccaaccaaaa
    25861 ttgatacaat ctaacgatgc accctctacg gcattctagg ggagtgcact tgcattcacc
    25921 caataaaaac cggcagttag caaagaactt atgtagtcgt atgttcttac tgttaacata
    25981 caagaggtct cctttccaca attgcttagc agtaaacggg aatttacaaa gctaatctct
    26041 tccattttct tatctttgtt ctaaaagtcc caaatggagc aactgtattt acatgaataa
    26101 atttatatac ttcccataca gccgttttgg ttgcctcgtc tgcccatttt cttttgtgtg
    26161 cagtgaatag atcttcatca ctcattgaat caatcatcat gttaatatca tcaatattac
    26221 gattgagaat ttcctctaat tctttcaatg atagatgtgc ataggtattt gtaaaccact
    26281 tatataactc tcctaactga ttccatttaa attgatcaga aggcgtttta acagataatc
    26341 catttctttc atcattttcc cattttagaa ttaaattcgt ccaaccaact tgatatgcta
    26401 aattttcagc aggtgttcta tccacttcct caactctttt atccttcaat tcttcaggaa
    26461 tagtttcaaa ttctaaaata tatttagtat aagtcctatt tatttctttt tttaattctt
    26521 ctttattttt atatgttctc attatattac ctccataaat tcctaattgt ctcctttaat
    26581 tcatctataa tttcatccac gatattttaa tccgttctac aatgcatatc tgatatgcat
    26641 tgactgtcta actcatatgt gaatgattta taaaatatcc caacgtctca tctaaagaaa
    26701 tgttgatcgt cagcaaggag ctaaaaaata cgaatatatt tcttttgtag taaaatcgga
    26761 ctggtttgca tatcattttc ttcgtaaata tcaaaatcat gttaactact atcaattact
    26821 aataaaaact accactttaa gcgttaagaa ctgttaagtt tagttaagtg aggatagttc
    26881 acaaaatcca ttgttaaact tcacgaaagt ggtaaaactc aaaatgcttt atataggatt
    26941 acagcatcgc tctttcttcg attgcgcgtt gggtaaaaaa tattatgaag taaaaattga
    27001 cgatgacacg ttccttacgg ctcatcagat gaaacagcta caaaaacgaa atgatcaact
    27061 cgaagaaaat ttaattctaa aaaagcgatt gccatattca cgcctcgctc gacgaactat
    27121 taaaggtcaa gatttacctg aagatcatcc tttttaggaa attgaagctt tttatgttgc
    27181 acaatgcatt tataatacta caatgatgtt ttcaccagat attcttctag ggtgcggtgt
    27241 aatgaaacag atacacttgc aaaagaaaat tcaccgcgaa tttactaaaa ttatgaataa
    27301 ttatgttaat cttccgaaat ttttttccaa aattaaggga tcaagctggt gttatagatt
    27361 gtttaaggtt ggcaaaaaaa taacttcttt ttaaacaatt atagaaaacc gatactctgt
    27421 taagttggtt gacacggtgt cgatttttat gactttctta ttctgaaact tcactaacgg
    27481 acagtaccta aaaagtctat agtatggacg tttacgagta ctattttatc aaaaatgctg
    27541 ctcatttcaa cttatatgtt ttagtgaact acccccactt a
//
LOCUS       DBBGRF010000037        26876 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000037 DBBGRF010000000
VERSION     DBBGRF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.037"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(164..388)
                     /locus_tag="ACIZD4_001818"
     CDS             complement(164..388)
                     /locus_tag="ACIZD4_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HGC5990730.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="ACIZD4_001819"
     CDS             complement(586..2166)
                     /locus_tag="ACIZD4_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGC5990731.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="ACIZD4_001820"
     CDS             complement(2567..3943)
                     /locus_tag="ACIZD4_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGC5990732.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5159)
                     /locus_tag="ACIZD4_001821"
     CDS             complement(4071..5159)
                     /locus_tag="ACIZD4_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGC5990733.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="ACIZD4_001822"
     CDS             5331..5765
                     /locus_tag="ACIZD4_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5990734.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="ACIZD4_001823"
     CDS             complement(5843..6376)
                     /locus_tag="ACIZD4_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGC5990735.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ACIZD4_001824"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ACIZD4_001824"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGC5990736.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ACIZD4_001825"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ACIZD4_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGC5990737.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="ACIZD4_001826"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="ACIZD4_001826"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGC5990738.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="ACIZD4_001827"
     CDS             complement(10101..10679)
                     /locus_tag="ACIZD4_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HGC5990739.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="ACIZD4_001828"
     CDS             11001..11471
                     /locus_tag="ACIZD4_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HGC5990740.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="ACIZD4_001829"
     CDS             complement(11579..12805)
                     /locus_tag="ACIZD4_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGC5990741.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(13559..13759)
                     /locus_tag="ACIZD4_001830"
     CDS             complement(13559..13759)
                     /locus_tag="ACIZD4_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC5990742.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(13893..14501)
                     /locus_tag="ACIZD4_001831"
     CDS             complement(13893..14501)
                     /locus_tag="ACIZD4_001831"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HGC5990743.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(14586..15056)
                     /locus_tag="ACIZD4_001832"
     CDS             complement(14586..15056)
                     /locus_tag="ACIZD4_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGC5990744.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(15104..16018)
                     /locus_tag="ACIZD4_001833"
     CDS             complement(15104..16018)
                     /locus_tag="ACIZD4_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HGC5990745.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            16164..16967
                     /locus_tag="ACIZD4_001834"
     CDS             16164..16967
                     /locus_tag="ACIZD4_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGC5990746.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            17145..18092
                     /locus_tag="ACIZD4_001835"
     CDS             17145..18092
                     /locus_tag="ACIZD4_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HGC5990747.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(18160..18453)
                     /locus_tag="ACIZD4_001836"
     CDS             complement(18160..18453)
                     /locus_tag="ACIZD4_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HGC5990748.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(18481..19146)
                     /locus_tag="ACIZD4_001837"
     CDS             complement(18481..19146)
                     /locus_tag="ACIZD4_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGC5990749.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(19286..19918)
                     /locus_tag="ACIZD4_001838"
     CDS             complement(19286..19918)
                     /locus_tag="ACIZD4_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGC5990750.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(19925..20992)
                     /gene="liaS"
                     /locus_tag="ACIZD4_001839"
     CDS             complement(19925..20992)
                     /gene="liaS"
                     /locus_tag="ACIZD4_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HGC5990751.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(20989..21720)
                     /gene="liaF"
                     /locus_tag="ACIZD4_001840"
     CDS             complement(20989..21720)
                     /gene="liaF"
                     /locus_tag="ACIZD4_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGC5990752.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(21889..22368)
                     /gene="greA"
                     /locus_tag="ACIZD4_001841"
     CDS             complement(21889..22368)
                     /gene="greA"
                     /locus_tag="ACIZD4_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGC5990753.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(22504..23679)
                     /gene="mltG"
                     /locus_tag="ACIZD4_001842"
     CDS             complement(22504..23679)
                     /gene="mltG"
                     /locus_tag="ACIZD4_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGC5990754.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            23883..25052
                     /locus_tag="ACIZD4_001843"
     CDS             23883..25052
                     /locus_tag="ACIZD4_001843"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGC5990755.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(25319..>26876)
                     /locus_tag="ACIZD4_001844"
     CDS             complement(25319..>26876)
                     /locus_tag="ACIZD4_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGC5990756.1"
                     /translation="LFPAFKNMEIFGFYDTAFHINRALSLESIFSSPINFETFRSYGM
                     QVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTLITLFICHYVMYEITKKHVTSSF
                     FAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLGFIKLYDSKKESWVMLAISMTLL
                     IYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIKLIKAAIVTLLLSLAFIGPMIEQ
                     TLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLSFGIGLTLLICLIILTFNFKKLG
                     ILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQAPWRFMIFSTLFISFSVSLFISP
                     QLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEMNFQGTYSNEQMENKLEEFENFD
                     YVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEITFTFKSSKGKTIVLPVFRYKGL
                     TVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSYTFFSKISLFISIITLIVLLFYC
                     IKLKIRTSHE"
BASE COUNT         8213 a         5313 c         4284 g         9066 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaaat ctaaaaactt
    13501 cataaataga caaaaagaca cgactctcta agaagtcgtg tctttattca acaaattatt
    13561 ataatttagt cacttcagca gcttgaggtc cgcgtgcacc ttcaacaatc gtgaattcta
    13621 cttcttgacc ttcttctagg ctcttgaagc cgtctccttg aattgctgag aaatgaacaa
    13681 atacgtcatc tccgccgtct actgtaataa acccaaatcc tttttcattg ttgaaccatt
    13741 taaccgttcc gtgttccata aatgtatatc ctccaaaaaa gttcttgcaa gtaaccttgc
    13801 aagaacatta tacccaattt agaaaacgct agcaagcttt cgctctttta ttttccaaat
    13861 tatttttaag actgatatga cggaggaaat ggttattttg ctgcttcgaa acgtttgttt
    13921 acttcatccc aattaataac attccagaat gctgcaatat aatctggtcg gacattttta
    13981 tatttcaaat aataagcatg ttcccaaacg tccaaaccta gaattggtgt ctttccttcc
    14041 atcaatggag aatcttgatt tgcagtagag gtaatagcta attttccatt ttccattaca
    14101 agccaagccc atccagaacc aaatcgtcca gcggctgctt ttttgaattc ttctttaaaa
    14161 gaagaaaaat caccaaaagc ttcattaatc gcttctttta tttctcctgt aggttcgcca
    14221 ccagcatttg gtgccatgat ttcccagaaa aatgaatggt tagcatgtcc gccaccattg
    14281 ttacgtacag ctgtcttgat atctgttgga atagcgtcca tatcagataa taattcttct
    14341 attgtttttt cgcctaattc tgggtatttc tcaattgctg aatttaaatt cgtcacataa
    14401 gtattgtgat gcttatcatg atgcagatgc atcgtttctt cgtcaatata aggttccaat
    14461 gcgtcatatg cataaggtag atctggtaat gtgtaagtca taaaaaaatt cctcctcaat
    14521 gttttcttaa taatgtctac attacaaaga gtaacaaaga gaaggaaatt cttcaattgt
    14581 tatgcctagt cgtctttttc actttgacct acttcttctt caaaaacctc agtttcttta
    14641 aaaataaaca acttgctgaa aatatagttc gcaaggataa caataatttg agtgatgatt
    14701 ttcgccacat actcattgct gttcataaca ttgatcaaca ataccattgc ccccatgtcc
    14761 aatccgtaag aaaggatacg gtagaagaag aacttaccgc attcaataag tgcatgtgta
    14821 aaattcggtg attttgaatg gaatacccaa agtttgttcg ttacaaaagc aaacaataca
    14881 gaacaaaacc acgaaataga attggataag gccatactta aatcaaaata ttggcgtgcg
    14941 agagcaaaac taacaaaatt tacaatcgta gccaaaccac caaaaaagag atagactagt
    15001 atctcccaat atccttttgc ttctaaatat ccttttaact gtcgatactg cttcatgagc
    15061 caacctacct tattaaaaat tcttatttat catactctat atttcaataa ctttcatctt
    15121 tatttaaaaa aattaatttt ttttgatcct ttgcctttgt ctctgcttgg atcgtcacat
    15181 gtgtaatacc atattttaat tttaataaag aaattatacg aggatatatc ttttcaatct
    15241 cgcttagtag ctgatcttca aaatcaatat gtccgtcgaa aataattatc ttttcgctat
    15301 actgccaaat atggacatga tgaacatcct ttaccccatc gattgcttca atttcttgtt
    15361 ccattttttc atagtcgata gcaggtgcac tttgtatcaa aatagcggca gcttttttga
    15421 tcaccattat cgcttctatc aatatatata tcgaaatgat cagtgtaata actggatcga
    15481 tccagtagat atcgaaaaaa cggatcaaaa ttgctccgat aatcacactt accgaagaca
    15541 gtgtatcact taacaaatgc aaataactag attttatatt caaactttca tctgcttctt
    15601 gtcgtaataa taatactgag aacaaattcg cgagcaatcc aataactgct actgttagca
    15661 tcaaatgact atttatcttt tctggtgaag tgaaccgctt gaatgcttca acggttaaaa
    15721 acaaggataa tatgatcaat atgaatgagt tgatgaaagc actcaatatt tctaaacgct
    15781 ggtagccata cgtacgtttt ttatttgctt cttttcgggc cattttttgt gccccgtaag
    15841 aaaaaataat tgccaatgta tcactaaggt tatggaaagc atctgaaaca agagacaaac
    15901 tccctgacat aatccctcca ataaattctg ataaagtgat caccgcattc aaaaccacta
    15961 ctccaaatag tttttttgat gatctctgtg gctgtgtagg cactattcct tcctccattt
    16021 tatttatatt ggatagtctt tagacaagaa taacattttt ttgatatttc accaatcatt
    16081 cagctgtttc cttaaagcac ttgtatttca cttgatactt cgctagaatt gcaagtgatg
    16141 acactactag atgaggagta cttatgacaa caaaacaatt aattatcagt tcctttatac
    16201 gattcaaaga cctaaaggag gcgagaaatg tcccattttg gaaagccatt gtctatcttt
    16261 tagttttgag tataattatg gctttgccaa tctcttttca agtttttcaa gtcttaaaca
    16321 acattcaatt ggatgggcaa aagattgcta ctcgcattcc tgattttaca atccaaaacg
    16381 ggcagcttca aaccgaagaa aaagaaggat tcatttacca aacaaactcc attatcttca
    16441 catttgatcc agagggaaaa cgaacagaac aggacatctc tactgatttg atggggaatt
    16501 ttgttagtgt cgggatgtta aaaaacaaac ttatcatagc tcttcctaat acaggcacga
    16561 cttctgcttt gttgaacaat aaccaattag aacttcccta caccaatgaa tctttaaaaa
    16621 acttaacagg taagcagctc cgttcttttt taagtgaagc atctatacca ctttggataa
    16681 aagtcctgac atttatattt tctatttatc ctagttttct gaatctgctg atcactttgc
    16741 tatttaccaa cattgctgct tttctctatg cacgctttcg actaacaaaa gctacttttc
    16801 ttgattgttt aaaaacattg atctattcaa tttcattgcc tactataatt gcaacaatct
    16861 tgatggtctt tcttccttct tttgacacta gcgccttcat tgcttttgca ggaatcttta
    16921 tttttgctca agctgtcaaa ggatgggcaa aaatatcgat caattaagaa ataaagacaa
    16981 ctcgttattt ctacttcaat agaccctttt agaggttgtg acattttttt gtcacagccc
    17041 cttttttatt tgaaaaatat ttctttctca aaaaacaagc aaggcgcttc aaagttcttc
    17101 ttgtatgcgc tacacttaga gtaaagaaag gcgggaaatt aactatgtca gaaagaatca
    17161 tttatgcaga tcgtccattt cgtgatgaat ttatcgaaga aatccatact atagcgcctg
    17221 gttatatctt taaaacagaa ttacaaccag aggatctaca aaatgtagag atcagtttgg
    17281 gctggaactc agactaccaa gaaaaactat tagcctcttc taccttgaaa tgggtccaat
    17341 ctatctcagc tggtgttgat cagctacccc ttgagacttt ttcaaagaaa catattttac
    17401 tttcaaatgg tagtggcatc cacagtgaat cgattacgga gcatgtctta ggaatcatcc
    17461 ttgggtattc tcgtggtctt tttcaagcac aaaaggcaca gagtgacatg aaatggttag
    17521 gttcatcggt ccattaccaa tctatccaag ggaaaaaaat actaatcatt ggaactggcc
    17581 atattggaaa aatgattgca aaaaaatgca aagcattaga catgaactgc tatggaatca
    17641 atacatccgg tcatccagca gaaggaatgg aaaagacttt ttctttaaat caactaaagg
    17701 aagttcttcc tgaagtagat ttcgtagtca atatcttacc tctaacggag gaaacaactg
    17761 ggctctttga tcagcatatg tttgaacact ttgatccaaa atctgtattc atcaatgttg
    17821 gccgtggtgc ttctgttaag acacaagatc tggtgcaggc tttaaataac cagcaacttt
    17881 cctttgcagc attagacgtt tttgaggaag agcctcttcc acaagatcat cctctttgga
    17941 aaatggacaa tgtactgatt acttcccaca ttgcaggttt gacacctgat tttcaaaaga
    18001 aattaatggc tattttttta accaatctga aaagctactt tgccacccat gagcttcaaa
    18061 ccaatcaagt aaaattgtct gcaggatatt aatagctgaa aacaatattt tcaaaagaaa
    18121 aaagagaagg tgacaaaaat tgtgtcaccc tctctttttt tattgttttt taaagtgata
    18181 ggttggctcc tccaggttgg gatcataatc aacaagtaaa tcatatcctt taaagaacca
    18241 ttcatctgct tcctcgataa aaaaaagtgt cccatcaatt tccactttct ttacaggatg
    18301 ttctggctgt tcaactgaca ttccaatcga aaaaccatca tgaacctctg ttttgccgta
    18361 gacttttcca aaaaaacgta ttccgtaagt ttctggcaga tcaatttctg agtcaaacca
    18421 cttttgtgct tttggcgtta ccgttaattt catcccaaca acctactttc tcttttcttt
    18481 ctattgattc atcttatcgt ctagaatatc cacatcgcct gtctctccaa taaccagtag
    18541 attatcattt tcacgaacat attcatctgc tgcaggagaa gcgataaccg tttgatctac
    18601 tcttcgtatg gcgactactg ttaagtcaaa acgttgcctg aaatttaatt cagctaatgt
    18661 tttgttgaaa aatttaggat tggagactcg gatttctgct aaagaatatt tatctgacaa
    18721 ctctaggtaa tctaaaatat tctttgacac taaattatgc gcaatcctta ttcccatgtc
    18781 tcgctcggga tggacgacgc gatcagctcc gatcttttca agtactctgg catgatactc
    18841 attttgggct tttgctaaaa tatttggtac gcccatttcc tttaccatca gagtaactaa
    18901 gatactggct tgaatatctt ctccaatagc gacaattaca tgatcgaaat ttcttatgcc
    18961 taatgatcga agtgtcattt catcctgtgc atttgccaca acagcatgag tggctatatt
    19021 catatattca ttgacccgat cttcattact atcaatagcc agtacttctt gaccagcttc
    19081 gatcagtgtt cggcagatac ttccgccaaa tcgtccaaga cctacaattg caaaattttg
    19141 tttcaccgtt ttcctccttt agtatcttct tttctcagta taacaaagcc tttacaaaaa
    19201 caaaagcaag catcattatt gtaaaaaagc caagaaaaat aatagttatt ttctcagctt
    19261 ttgattatcc tctttatcat cgtttttatt tcaccaaacc atgtttgaat gcatagatag
    19321 cggcttgtgt acggtcttcc acttctagct tagccaatat attggaaaca tgtgttttta
    19381 ctgttttcag tgtaataaac aattcgtccg ctatttcctg attacttttt ccttcagaaa
    19441 tcagcattaa aatttcattt tcccgattcg ttagttcttc atgtaataca ggctcatttc
    19501 gccgactcat tttttccatc atttttgttg tcacttctgg ttctaatact cgctcgccac
    19561 gttgcgttgc ccttatagca tcagcaattt catgtgcggt agaggtcttc aacaaatacc
    19621 ctgctgcacc tgcttcaatg gcaggataaa ctttttcgtc atcaataaaa ctggttacga
    19681 taatgatttt agcttctggc caatctttta agattgcttt tgttgattcg ataccatcca
    19741 tttcttccat gactaagtcc attaaaatga cgtccggtcg aagtgtcatc gccttctcat
    19801 agccttgtcg tccattttca gcttctccaa ttacttcaat gtcttcttga atagataaat
    19861 aaaaagagac gcctaagcgc accatttcat ggtcatctac taataaaact tttatcatcc
    19921 ttatctatgc ctccttcatc aaagggacct tgatttctac acttgtacct tgacctttaa
    19981 aactaatgat ttttactgtt ccaccaatac cagctactcg ttctttgata ttgttcaatc
    20041 cataacttcc cgttttcgtt tcattcatat taaaccctgt tccgtcgtca ataatacgta
    20101 acaaaagatt attgtctatt ttgtgcaaat atacctctaa ttcattggct ttagcatgtc
    20161 ttaatgtatt tgataacaat tcttgaacga ttcggaacaa gtgatcctca atggaactag
    20221 atagttttac atcttctaca tcccatttca gcgaaatctg gattttattt tgcaattcct
    20281 tcaataactg ctcgatacct tgctttaaac ttttctcttc taaattgact ggacgtagat
    20341 gaagaagcag cgcacgcatc tcagactggg aagcgttgat gatctctgct accattttca
    20401 actgcttgcg aaacatttct ggtgtctcgc ttttttctgc ttgctccgtc aatgccgaca
    20461 tcatcatcat tgctgcaaac aattgttgcg aaactgaatc atgcagctca cgggctaatc
    20521 gatgtctttc taattctaaa atttcttctt tggtttgtcc atctacatat tggggacggc
    20581 tcgttacaat ttgtaattca ctagatactt caatcatttt ttcttttatc ttagtgattt
    20641 ccttatcaat atctttgatg tataaatcgt ccgatgcact tgggatcgga agaagcaaca
    20701 atttggattc ataattgcca gaagaaagtg cacgcagctt ttcttcgatt ttcccgtatt
    20761 ttgtcttttg aataagtgat aataatagaa agacaattaa tcctacacct aaggaaatgg
    20821 ctaacaaatg gaagataagc ggaacatata ataaacgtgc acgcagtaat tctccccacc
    20881 aatgactttg attgctggca taaaaataag tgaaaagtga aaatagaata ataaggaaag
    20941 ccgcaatccc cgaataaaca gctagcatcg ctctggatat ttttcccatc atattcgtat
    21001 cacctcgaca tctccaatca aggtattagt aataatcttc aatctacgag ggttttcatc
    21061 ataatcactg ctgtagattt tgatttgttc atttttcaaa gaaaattgct cttcttcaaa
    21121 caagacattt cctactaatg tcgcatgctc taatcggatg gctacgccca aaggtactaa
    21181 gatccgtgtt ctgcctatcc cttttcttac aatcacaata ttatcatctt ttggcaaaag
    21241 cgtattgccc aaatctatga tagtatcacc agaaatgacg gcgatgttga tatcgtccca
    21301 ttcatagacg tcgtttccaa tacgttggtt accgaataat tgctgtcttt tccgctcatt
    21361 attatgtgtt tttaattgct ctgtttggat catcatgatc tgtttctttc gccaaaaagc
    21421 atttttggtt aaatctatcc ctgaaatctc tacacctttc agaccaataa ataaaacggc
    21481 aaatacagcc atcatccata aagcaggact gttgactaag ctaaaaaaaa tgaccaaact
    21541 tcctaatatc aattgaaaat tttgaaattt agtacgagga tgtttgcgca tagctagata
    21601 tatattgaaa ataccgaata tcactaaaag caaaagtcca gtattgttta cgatttgcca
    21661 aacagcaaat aacagcagta gtgcttcaac taccacaaaa aaacgccaag aactattcat
    21721 cgctctttct ccctcctgac acattctcat ttcatcatac ctattttttt aactgttggc
    21781 tataggactt tagatgtaag atcgtttgtt gaaatctaaa atacacaaag agaaaaagat
    21841 ctagagtgta tcatcagtaa gatgaactct ctagatcttt cagtcagact acgcttgttc
    21901 tactttgacg attttaacta acatatcgcc acctggagta gcaatagtta cttcatcatt
    21961 tttacgtttg ccaatcaatg cttgcgcaat aggagaatca ttggaaattt tgccagaaaa
    22021 cggatctgct tcagcgcttc cgacaatcgt gtactcttct tcttctccat ctggtagttc
    22081 gatgaatgta actgttttac caattgatac ctcatctgca tctacaccgt cgttatcgat
    22141 gatttgagca aaacgaatca tattttcaat tgttgtgatt cttccttcaa caaatgcttg
    22201 ttcatctttc gctgattcat attcagagtt ttcggaaaga tctccgaaac cgcgggcaat
    22261 tttgattcgt tcaatgattt ctccgcgttt gactgttttt agttcttcta attctttttc
    22321 taatttttct ttaccttcta gagtcattgg ataaactttc tctaccatgt gtaacgtctc
    22381 cttttttcga taaaataccg caaaaggtaa tcttttgagg aatatagtcc aaaaaagatt
    22441 accacgcttt tcttcaaatg taaatgtttt tctaaaaatg atcaatgtct agagcctgtt
    22501 tttctaagaa ttatttacat atttttccac taattccata tgttcttcat aagttttagc
    22561 gaaataaaca tttccagtgc tcgtatctgc tacgaaataa taatagtcat tttctgctgg
    22621 ttctaatact gccttgattg cctcttcgct tggattgtca aaaggtccag gtccatagcc
    22681 ggtattggta tacaaattat atggtgaatc tacagctgta tcttcatacg tcactaattc
    22741 tttgtgttca cctaatgcgt ataaaacaga gatatctgac tgaagtggca tatttgcttt
    22801 gattcggtta aagaagactt gtgcaatgtt tttacgatca ttttctttta cgccttcttt
    22861 ttcaactaga gaagctagag ttaaaacttc ttgtacagtc aaatttttct gcttgatagc
    22921 tgaataatag ttttgcatga ccgtattcgt cttgttcacc atttcaatca ctagatcctt
    22981 aagcgaagta ctcgtgtaat aatcatatgt ggctgggaat aagtaacctt ccaaacggta
    23041 ttttgtgttc tcagctttag atgcactttc caacagttct gggaattttt ggtgcaactc
    23101 gttaaagaaa gtctcatcat tcactaaatc taaaaattct ttcttgtctt taccagttac
    23161 cttcgctacc cgttcagcaa tctgatcgat atcgtaccct tctggaatgg caattttccc
    23221 atctgcaact tttgttggct cagaagtacc gccttcttgc aactgtttgc caatctcgtc
    23281 aagagtcata ttaggcgcta actgataata gccagcttga aagccagtta aatttttaaa
    23341 ttttgtataa taattgaaaa caatcccgct tttaataata ttgtccttct ccaaaatctc
    23401 accaatctgc ttgttagaag agccactcgg gatctcgact tggactaatt ggtcatctga
    23461 tttatctaaa ggcttcaacc cgctatctac ataacgatac acggtaaatc caagaaatcc
    23521 gccaataatc aataatgtaa gagcaatcac taaaatgatc ttcctcacaa tcttatcttc
    23581 ttttttacgc agatttctcc gcttgtcgat tatatctgct gtagctgcct tactggcttc
    23641 ttttttatct ttacttgggt gttgtttgtt tcctgacaaa acaactcctc cttactatca
    23701 agttcgtaac tttattcatt atacatgata tttgaattgg cgtgaatgat tttatttaaa
    23761 tattctatca aaaatgtaag tagtaaatcc attactataa gattaaaata aatgttatca
    23821 agatacaagc tattttagct ttattctttc tgtaaaaaag aaaggagact aaataaacta
    23881 ttatgaaaaa aggaaaacat gctaaaaaaa gaaaatattc atttttaatg atcgttgtcg
    23941 tgttgtttag ccttagtgcg ttctctacag gaactattct tggatggcaa ttttacaata
    24001 atgaacactc tcagatagtt gcccatgctc aatcagctca aaaaaagttg atactgacta
    24061 ccaatgaaca acagctcgtt gaaaaaatcg atcaactatt aagaaaaaat gattatattg
    24121 gctcaattta cgtaaagaaa aataatcgca tcatcatgga aaaaggctat ggctatgcga
    24181 ataaactcac gcaacaacca aatgatcctt ctctttatta tcagattggt tcggttcaaa
    24241 aagcattgac tactcttttg attttaaaac aagtcgagcg tgggcacctt tctttagata
    24301 ctaagctggc tcaattctat ccacaaattg ctggcagcca gcaaattact atccgtgact
    24361 tgctgtatat gcgctcaggc ttgcaccgaa ctgcttctcc aaccataccg atgactgatg
    24421 aagaagtcgt tcaatttgcg attcagcact taaaatttac agattatcag acctctcatt
    24481 atgattcatt gaactttacc atattgactg gaattttgat caaattaaca aatcaaccgt
    24541 atgaaaaatt attgaccgat gatatcatcg aacctttagg attacagcat acaaaatttt
    24601 atgaccaagt caaaaattca tccaatcatg cactatccta tcaaatgtct aaagaggatg
    24661 attactttaa accactgaca gaatctgaaa cagagatcca taacgaatta gggactggta
    24721 atatcagtat gtccgtctat gatttaaata cgctgtttac acaagtttta tctggaaaac
    24781 tagtttccaa agacttactc ttctcattat ggcgtgaaaa tgcgaatgga catccatata
    24841 gtggtggggt atatagcgga gataattata tcctgtcgca aggaaatatc gactcttttg
    24901 atacatctgc tatatttagc aaagattcac aggatgctat catcatggaa agcaatataa
    24961 aagctgacaa aactatcaaa ctgcctactg ctgatctaag aaaccaaatc tatgacctga
    25021 tggaaggaac tactaagttg gcaaatagct gatatgatga aaagatagca aatactactt
    25081 ctttgaatag catttgctta aaaaaagtac tcgactaaac gtaggaaaga gtgtgggaca
    25141 aatctaaaaa tcaatttttg ctacagactt taattccaaa taaacagaac agaaagaggt
    25201 gttcttcttt ctgttctgtc caaattattc taagatttct ctttaccaac attatttgac
    25261 aaagggccta ttaaatctaa aatagtatct ttagattgct aaaatatgtg ctagcaaatc
    25321 attcatggct tgttcttatt tttaatttta tgcaataaaa aagaagaaca attagcgtga
    25381 ttatagaaat aaataatgag attttagaaa aaaatgtgta tgaatacctg attgttactt
    25441 tatttattcc actttcactt tttactgtaa caaaaggacc tccttgtttt agtactgtag
    25501 cattttttga attaacagta accgttaatc ctttataccg gaatacaggt aaaactattg
    25561 ttttgccttt tgaagattta aacgtaaatg taatttcatc tttatttgga gaaaagctac
    25621 tataaataac ttgaccatct tctgtaactt gatggttttt caaaagcaat tgatcttttt
    25681 tatagcctat aggtacataa tcaaaattct caaattcttc aagtttattt tccatttgtt
    25741 cattagaata agttccttga aaattcattt ctttcaccat gttaactact gatgaataat
    25801 ttaaaattga aatagctaat attaataata gtataaaatt tcttctcctt gtataagaaa
    25861 atttttccaa ctgtggagaa ataaatagag atactgaaaa agatatgaac aatgttgaaa
    25921 atatcataaa acgccaagga gcttgaataa tatttaaagg agtattttgt aaggcaaacc
    25981 atggaaatat ttttgtacaa agtagaatag atattatacc cattatataa gtgattttag
    26041 ataagattcc taatttttta aagttaaatg ttagtataat taaacaaata agcaaagtta
    26101 agccaatacc aaatgatagt aattctgaat ctatacttcc aatcaaaaac tctttaccca
    26161 gataaattgc tcttttttgt aatatatcca cataaggtct attcagatct tgatacaatg
    26221 tctgctcaat cataggacct ataaacgcta gtgaaagaag taaagtaact atagcagctt
    26281 ttattaattt aataattaag aagatttcta ttttcttttt ccgataaaat tgaataatta
    26341 aagcaattat aatcattacc atagtcatag ctacagaaag aacatgagtg taaattaata
    26401 aagtcatgct aatcgccaac ataacccaag attctttttt tgagtcgtaa agctttataa
    26461 acccgagtaa aataagagga agtattgaca ttgcgagtaa ttcccccatt gcccctcgaa
    26521 gaaatatttc tacactccta aaagaagatg ttgtatatat aatagcgaaa aaggagctag
    26581 taacatgttt tttggtaatt tcatacatta cataatgaca tataaataga gtaatgagcg
    26641 taacaatata aagaaaaagg ttatagccta ttgctaaatt agtaaacttg atcaataaaa
    26701 ataaaggata tagagttaac catgggtaaa aattatttac ttgcatgcca tatgatctaa
    26761 acgtttcaaa attaataggg gagctaaaaa tagattctaa acttaacgca cgattaatgt
    26821 gaaatgccgt atcataaaag ccaaatattt ccatgttttt aaatgctgga aataaa
//
LOCUS       DBBGRF010000038        26529 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000038 DBBGRF010000000
VERSION     DBBGRF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.038"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(99..1229)
                     /locus_tag="ACIZD4_001845"
     CDS             complement(99..1229)
                     /locus_tag="ACIZD4_001845"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGC5990757.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACIZD4_001846"
     CDS             complement(1878..3080)
                     /locus_tag="ACIZD4_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5990758.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACIZD4_001847"
     CDS             complement(3140..3343)
                     /locus_tag="ACIZD4_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGC5990759.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACIZD4_001848"
     CDS             complement(3485..4552)
                     /locus_tag="ACIZD4_001848"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC5990760.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACIZD4_001849"
     CDS             complement(4610..4717)
                     /locus_tag="ACIZD4_001849"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990761.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACIZD4_001850"
     CDS             4880..5692
                     /locus_tag="ACIZD4_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990762.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACIZD4_001851"
     CDS             complement(6066..6257)
                     /locus_tag="ACIZD4_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990763.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
     gene            complement(6502..6732)
                     /locus_tag="ACIZD4_001852"
     CDS             complement(6502..6732)
                     /locus_tag="ACIZD4_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990764.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVSILIDNKLR"
     gene            complement(6716..6913)
                     /locus_tag="ACIZD4_001853"
     CDS             complement(6716..6913)
                     /locus_tag="ACIZD4_001853"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HGC5990765.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="ACIZD4_001854"
     CDS             complement(7059..7937)
                     /locus_tag="ACIZD4_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC5990766.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="ACIZD4_001855"
     CDS             complement(7976..9094)
                     /locus_tag="ACIZD4_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HGC5990767.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="ACIZD4_001856"
     CDS             complement(9091..11190)
                     /locus_tag="ACIZD4_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HGC5990768.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="ACIZD4_001857"
     CDS             complement(11241..12062)
                     /locus_tag="ACIZD4_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC5990769.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="ACIZD4_001858"
     CDS             complement(12059..12868)
                     /locus_tag="ACIZD4_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGC5990770.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="ACIZD4_001859"
     CDS             complement(12889..13383)
                     /locus_tag="ACIZD4_001859"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC5990771.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13895)
                     /locus_tag="ACIZD4_001860"
     CDS             complement(13395..13895)
                     /locus_tag="ACIZD4_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC5990772.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(13960..16656)
                     /locus_tag="ACIZD4_001861"
     CDS             complement(13960..16656)
                     /locus_tag="ACIZD4_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC5990773.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="ACIZD4_001862"
     CDS             complement(17084..18157)
                     /locus_tag="ACIZD4_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGC5990774.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="ACIZD4_001863"
     CDS             complement(18154..18981)
                     /locus_tag="ACIZD4_001863"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990775.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="ACIZD4_001864"
     CDS             complement(18982..19788)
                     /locus_tag="ACIZD4_001864"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990776.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="ACIZD4_001865"
     CDS             complement(19800..20885)
                     /locus_tag="ACIZD4_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990777.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="ACIZD4_001866"
     CDS             complement(20902..21444)
                     /locus_tag="ACIZD4_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGC5990778.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="ACIZD4_001867"
     CDS             21702..22691
                     /locus_tag="ACIZD4_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HGC5990779.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="ACIZD4_001868"
     CDS             22688..23425
                     /locus_tag="ACIZD4_001868"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGC5990780.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="ACIZD4_001869"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="ACIZD4_001869"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGC5990781.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="ACIZD4_001870"
     CDS             23989..24621
                     /locus_tag="ACIZD4_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC5990782.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="ACIZD4_001871"
     CDS             24706..25353
                     /locus_tag="ACIZD4_001871"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HGC5990783.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="ACIZD4_001872"
     CDS             25358..26341
                     /locus_tag="ACIZD4_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HGC5990784.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
BASE COUNT         8115 a         5602 c         4498 g         8314 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttaccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgct
//
LOCUS       DBBGRF010000039        26227 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000039 DBBGRF010000000
VERSION     DBBGRF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26227
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.039"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(188..1207)
                     /locus_tag="ACIZD4_001873"
     CDS             complement(188..1207)
                     /locus_tag="ACIZD4_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGC5990785.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1204..1428)
                     /locus_tag="ACIZD4_001874"
     CDS             complement(1204..1428)
                     /locus_tag="ACIZD4_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGC5990786.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1425..1718)
                     /locus_tag="ACIZD4_001875"
     CDS             complement(1425..1718)
                     /locus_tag="ACIZD4_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990787.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(1755..1892)
                     /locus_tag="ACIZD4_001876"
     CDS             complement(1755..1892)
                     /locus_tag="ACIZD4_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HGC5990788.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(1894..2325)
                     /locus_tag="ACIZD4_001877"
     CDS             complement(1894..2325)
                     /locus_tag="ACIZD4_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990789.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(2339..2833)
                     /locus_tag="ACIZD4_001878"
     CDS             complement(2339..2833)
                     /locus_tag="ACIZD4_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990790.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(2833..3282)
                     /locus_tag="ACIZD4_001879"
     CDS             complement(2833..3282)
                     /locus_tag="ACIZD4_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990791.1"
                     /translation="MTDIVKIKQSGVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            complement(3286..3903)
                     /locus_tag="ACIZD4_001880"
     CDS             complement(3286..3903)
                     /locus_tag="ACIZD4_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990792.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            complement(3903..4811)
                     /locus_tag="ACIZD4_001881"
     CDS             complement(3903..4811)
                     /locus_tag="ACIZD4_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HGC5990793.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            complement(4824..7583)
                     /locus_tag="ACIZD4_001882"
     CDS             complement(4824..7583)
                     /locus_tag="ACIZD4_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HGC5990794.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYER
                     PAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSG
                     YLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINW
                     ARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISSI
                     VIPPK"
     gene            complement(7580..8284)
                     /locus_tag="ACIZD4_001883"
     CDS             complement(7580..8284)
                     /locus_tag="ACIZD4_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC5990795.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(8296..10605)
                     /locus_tag="ACIZD4_001884"
     CDS             complement(8296..10605)
                     /locus_tag="ACIZD4_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HGC5990796.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(10800..11264)
                     /locus_tag="ACIZD4_001885"
     CDS             complement(10800..11264)
                     /locus_tag="ACIZD4_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990797.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(11264..11890)
                     /locus_tag="ACIZD4_001886"
     CDS             complement(11264..11890)
                     /locus_tag="ACIZD4_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC5990798.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(11897..12262)
                     /locus_tag="ACIZD4_001887"
     CDS             complement(11897..12262)
                     /locus_tag="ACIZD4_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HGC5990799.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(12252..12590)
                     /locus_tag="ACIZD4_001888"
     CDS             complement(12252..12590)
                     /locus_tag="ACIZD4_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990800.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(12580..12906)
                     /locus_tag="ACIZD4_001889"
     CDS             complement(12580..12906)
                     /locus_tag="ACIZD4_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HGC5990801.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(12884..13165)
                     /locus_tag="ACIZD4_001890"
     CDS             complement(12884..13165)
                     /locus_tag="ACIZD4_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HGC5990802.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            complement(13167..14531)
                     /locus_tag="ACIZD4_001891"
     CDS             complement(13167..14531)
                     /locus_tag="ACIZD4_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGC5990803.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(14544..15113)
                     /locus_tag="ACIZD4_001892"
     CDS             complement(14544..15113)
                     /locus_tag="ACIZD4_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HGC5990804.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(15085..16272)
                     /locus_tag="ACIZD4_001893"
     CDS             complement(15085..16272)
                     /locus_tag="ACIZD4_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC5990805.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(16336..18063)
                     /locus_tag="ACIZD4_001894"
     CDS             complement(16336..18063)
                     /locus_tag="ACIZD4_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HGC5990806.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(18060..18512)
                     /locus_tag="ACIZD4_001895"
     CDS             complement(18060..18512)
                     /locus_tag="ACIZD4_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HGC5990807.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(18624..19004)
                     /locus_tag="ACIZD4_001896"
     CDS             complement(18624..19004)
                     /locus_tag="ACIZD4_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HGC5990808.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(19001..19387)
                     /locus_tag="ACIZD4_001897"
     CDS             complement(19001..19387)
                     /locus_tag="ACIZD4_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HGC5990809.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(19389..19667)
                     /locus_tag="ACIZD4_001898"
     CDS             complement(19389..19667)
                     /locus_tag="ACIZD4_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990810.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            19715..20443
                     /locus_tag="ACIZD4_001899"
     CDS             19715..20443
                     /locus_tag="ACIZD4_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HGC5990811.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(20589..21065)
                     /locus_tag="ACIZD4_001900"
     CDS             complement(20589..21065)
                     /locus_tag="ACIZD4_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HGC5990812.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(21025..21381)
                     /locus_tag="ACIZD4_001901"
     CDS             complement(21025..21381)
                     /locus_tag="ACIZD4_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990813.1"
                     /translation="MKKVNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVL
                     KIEQNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIR
                     GGVCEISLVKRLPRTR"
     gene            complement(21359..21544)
                     /locus_tag="ACIZD4_001902"
     CDS             complement(21359..21544)
                     /locus_tag="ACIZD4_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990814.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(21545..21817)
                     /locus_tag="ACIZD4_001903"
     CDS             complement(21545..21817)
                     /locus_tag="ACIZD4_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH/PUA domain-containing protein"
                     /protein_id="HGC5990815.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(21814..22014)
                     /locus_tag="ACIZD4_001904"
     CDS             complement(21814..22014)
                     /locus_tag="ACIZD4_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990816.1"
                     /translation="MKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDKY
                     LGEGFCGDSLFDDERILKEETE"
     gene            22142..22354
                     /locus_tag="ACIZD4_001905"
     CDS             22142..22354
                     /locus_tag="ACIZD4_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990817.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(22387..22581)
                     /locus_tag="ACIZD4_001906"
     CDS             complement(22387..22581)
                     /locus_tag="ACIZD4_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990818.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(22594..22776)
                     /locus_tag="ACIZD4_001907"
     CDS             complement(22594..22776)
                     /locus_tag="ACIZD4_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990819.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            complement(22773..22913)
                     /locus_tag="ACIZD4_001908"
     CDS             complement(22773..22913)
                     /locus_tag="ACIZD4_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990820.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(23403..23768)
                     /locus_tag="ACIZD4_001909"
     CDS             complement(23403..23768)
                     /locus_tag="ACIZD4_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990821.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(23808..24110)
                     /locus_tag="ACIZD4_001910"
     CDS             complement(23808..24110)
                     /locus_tag="ACIZD4_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HGC5990822.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(24110..24409)
                     /locus_tag="ACIZD4_001911"
     CDS             complement(24110..24409)
                     /locus_tag="ACIZD4_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990823.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(24402..24566)
                     /locus_tag="ACIZD4_001912"
     CDS             complement(24402..24566)
                     /locus_tag="ACIZD4_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990824.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(24572..24841)
                     /locus_tag="ACIZD4_001913"
     CDS             complement(24572..24841)
                     /locus_tag="ACIZD4_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990825.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(24853..25602)
                     /locus_tag="ACIZD4_001914"
     CDS             complement(24853..25602)
                     /locus_tag="ACIZD4_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990826.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(25599..>26227)
                     /locus_tag="ACIZD4_001915"
     CDS             complement(25599..>26227)
                     /locus_tag="ACIZD4_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HGC5990827.1"
                     /translation="ATINEEVNIDRLKTMYDGYDGDRVIEIRFIDPRRFTVQQRNFIY
                     ALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLKDESNTTVSDANVLANIILDFIF
                     EHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKTGADIDHFDKALGRRKRKEVDHA
                     EYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQKTIKKLNIGGEK"
BASE COUNT         7286 a         5580 c         4077 g         9284 t
ORIGIN      
        1 ggttgttgcc acataaagcc ataaacaatc aaccagtaga atgtgtggca acaaacctgt
       61 tatcgcatag cttggagtgt gactattatg ggtgatagtg aagatatgcg ataacatcac
      121 tattttatcg aatgattttt atagttgtca atatagttat gtaatgctcc tcaacgagga
      181 gctattttta tcgtttagga atatttaaat accaacgttt gtcatggaaa tcttgcgcac
      241 cgcctttagt gtttccctct ggatcattcg ttgcccgcat catgacatag actttcttat
      301 tagggaagtt acgcatgtta aaagatacat gatagccaac atttccagaa gtattataag
      361 cttgatttac atctgatcta taaattccat cagctcttac tcgagctaat tctttcccag
      421 tattgtaatc cataatgaag atatactcgt atttatagtt agcaatgtgc catccagcta
      481 catgcaaatt tgcattttcg atttctccaa actgatcaat gtgggcgtaa ttcgttccat
      541 ctgtcagtgt aggattagct gcaccagctc gtgttggatc aatgacaggc ttgttttcag
      601 aagttgttgg attttcatcg gtaaatccat gagctaaatc atatgctaat ttttctttac
      661 ttacgcccat ttcagaaaga taaccgtaag gatctgtatg atcgccccag atgttttgtg
      721 ttacccataa atgcgatttg attcccggtt ggttataagg agtgtccaac gttaatggaa
      781 taccatattt cattgctgaa tctctagcca attcaacgta tgccttgtag tttttctcaa
      841 acgttgcttt atcatgtgtg tgttgtaact caatctgcac aggactgttg gcattagcat
      901 acgaaccagc accgtactgt acataaccag gttgaccgac ttgataaaca attccgccgt
      961 ctcccacaat ataagcagta taagcgctag tccatgaacg ttgcatatac tgcgcttcat
     1021 tgcgtcctgt tgctgtttca ttagccgttt catgcagtaa aatatactga ttatttgcta
     1081 cttgtgagct accttcattt gcgcccaaat taaattcatt gttgatagta taggcaaatc
     1141 cgttaattgg caataaaaaa agagccgtta acaggctcat cgcagtaata gtaattttct
     1201 ttttcatttg tttcctcctt cttcgctttc agccgagaac attttgtagg ttcgatttga
     1261 tacacccaac acactcccta aaaacgcgcc aaaaccagta atgatgacaa cacagatatc
     1321 tgtgtactgc caattgagcg ctttaccaac taaccccacg aaagtagcta gtgcgggaat
     1381 aattaccagt gcgaaccatt ttagtacttc gaacgtttta ttattcattt tcttctctcc
     1441 ctaaacaaag ttttgatttg ttgcgtgtgt tccaccaatt tttctgtatg tgtatctaat
     1501 ctttcatcgt gtttctttag ttcttcatga atcatcaatc gatctgattt gctcgattct
     1561 aaatctttag tcagcaaatc taaattgtgg cttacttttg aaagagtctc agtaattttc
     1621 gagaaagatg cagcaatcgg tctaattact aataaaatca aagaaacgat agcggttatt
     1681 gatcctgcta tcattcccca ttcccctaaa ttaatcatgt gacaactcct ttaccttaaa
     1741 taaaaacgca tcaattaaga tgcgctctta tctttattaa tgattttatc tgcttcttcg
     1801 tctgtaatgc ataatggaac gaaaaccatt acttgttcgt tagtgaaaca gccccagtca
     1861 tacattagtt tgatatcttc atatgaatac atgttacttc ccaccttgta attgtttttt
     1921 gatttcttcg atttccttgg tattttgtac agaagcaagc atcgtttttg aattcaactg
     1981 cgctaaactt tctgactttt ctttcaataa gacattttct tgcttgattg ctacattgtt
     2041 tagcattgct ttagaattta gctgtttcaa ttcatcattt tctgccttca gcgtttcgta
     2101 taatgcctta atattagcca attcatctac gctatcaaca gcattccctt ttttctcttc
     2161 ttcagtagct aactcaaccc actgtttttt atcaaaatca aatcttggtc tccagttagg
     2221 aactggtggt ttaatctctg tacagttttc agggatattt tcttgattgt tcaaaatgat
     2281 ttgctcgaat ccgtaaggct tgattgattt gtaaactact ttcattagat ttcctccctt
     2341 aaattgaata agtgataaca aatgaataag ctgatccata acttgaattt cttctccatt
     2401 taatggctcc gtctgcgcca atagatagtt gagcactgtt caaagtagaa cggtctattg
     2461 acccaaccag ttgttcaaaa ctaattggtg tccgatagcc ttctggaaca gttaaaataa
     2521 ccgaatcatt cccgccacta ctttttccgt ttaaagccac aaaatatata gaaactgttt
     2581 ttccttcacg ataaagcttt gctgtccctg tattaccgtt agtgacaacc agatttacca
     2641 cttcatatct gttatcatca gtcgtcaaaa cacgtttatt attgattgtt acagaacctg
     2701 aaaaattctt atgtcctgca atggcttggt ctccatctgt ctgcaccaat gcttctttac
     2761 catcaatagc ttctacatgc gtttttaagt atttagcaac tccgtcttct tttaattgaa
     2821 caatatcagc cattaaaccg tccccacttt ctcaaatgta atattcgcta atccatcaag
     2881 tttcacttta tcggttgctg acattaaacc tgctgtcgta gttgtagcat tacctggatt
     2941 tttctgtgct ccagctgcaa ttccatccaa cttagtttta tctgtggacg acatcaaccc
     3001 atttgctgta gttgtagcta cagctgtagt tgtggcattt attccaggat cacctttatc
     3061 tccctttggt aaaacaaaat taaatctagc tgcagatgat gttcctacat tcgtaacaga
     3121 agcggttgaa ccactagaaa cggttcctat ggtaattgtt gctgcttggc caggatcgcc
     3181 tttatctccc ttcaccgttg ttggtttgcc ttctatagca ttccaatgag tttgtggata
     3241 aacctgtaca ccgctttgtt ttatttttac gatatctgtc attttctata cctccccgat
     3301 tttttcaaaa gtaaaatttg gaattctttc gtttgtgtaa ttttctgctt gatttacagc
     3361 ttcttggaat ttttgatcta catatgactg attaacacca ccagtcccac taccacctgt
     3421 agaactaatt gttccatctt ctgcaattga tatatttgca cctgctttta atatttttag
     3481 agattctaat tttcccttta attcttcaga gaaattgaag tctgtttgct tagttgcaga
     3541 taaaacacct tcttcagtaa cttctaagag ttccccaact tttatacctc ctaattgttc
     3601 aggagtagca atcggcaaaa tatatgttcc accttctcca tttacgatct tttgaaacat
     3661 ttcagcagta agaataccat cgcttgtctc gcttgcataa ggtagttcag taattgcatt
     3721 ctctaatcct aaatcagctt tcgttaaaat gactgcacca tatttaccat taaccgaaag
     3781 aacttttgat tgtcctgata tcattttttc taagcctaaa actgcagaaa catgtgtaat
     3841 tggcataaat tgacgtttaa caccagattc atcagtctcc atcattctct ttactttaac
     3901 catcaaatca ccccaacttt ctcaagagtg aaaacattct gttttggatc atcaacagtt
     3961 gcaataatca aagctccttc ttcaattgga aattctactg tttcaatttt ttcgacttcg
     4021 tgattatctg aaaagagatc gtcttgaaga atatcagtca cttcaatttc accgtattca
     4081 atcgtgaaaa gtgctgcttt cattttttga tacaaataat ttagatcgga taggaaacgt
     4141 tcagaaatcg attcatggcg tacaccttga agatctacac gtgcatccat taattcggct
     4201 aacattactc cacctggatc gatagacttc aaaatatcct tgattgattc aaaccatgac
     4261 aaataatctg attcttgtcc ttctctccaa tcttggaaac tattctcctg ttcttctctc
     4321 cagcgatcaa attcttcttt cctttcattc atccagtccg taaaatcgcc tttattttca
     4381 ttaataaaat ctgtcatatc agcaattaaa tcttcaattg attgccaata agaacccatt
     4441 tctccttctg tttttgaaac agcattgatg acaaaatagg agaagtcttg agttgttcca
     4501 atcaagtctt ctcctttaaa tataatgaaa ttggctgttt gtcgatgcaa acactgcatg
     4561 gaatatttat caaaaatata tttgattttc ccttttttag catccacaat tcttgtttct
     4621 aattggactg gatattttcc gccaacaact gattcaaaat ataccttaca ttctgataaa
     4681 tcatatggaa gaccattttc gacaattgta gcttccataa cttcagtgtt tttattgcct
     4741 tgtcgaactt gaatcatccc cacgtaatta tagggttctg ttgtacttaa tatgacattc
     4801 cactttgcca ttaaatcacc tccctatttt ggtggtatga caatggaaga aattgcactt
     4861 gcactataat actggcgatc taactttcca caaatcatac ctaactctgt gttttgttca
     4921 taagtttgca tacgaccatt agctaagcct cggataacgc cagtatgtcc ataagttccg
     4981 tctgcaaacc atgaacccac ttgtccacct cttgcccaat taataattgc accaactact
     5041 aattgatcat atctagggtt ttgaatcact ttccaaccaa cagcagacca atcataggca
     5101 ataccaatat cagatgctgc agaagtattt cctatcacat gagttaaacc atattttgtt
     5161 ccagcaccca tgccacaacc acccagatat cctgaatatt ctgcagacaa gccataacac
     5221 tgaccattgc caattcgttg tccaatcaaa gactctaaat gttttagtcc tgcttctcca
     5281 gtagctcctc ctggttttaa atctttaaat ttgttatacc agttaactgc ataatcttga
     5341 cgttcaggat gtgtcgctgc cggacgttca tagtttcgtt caaaagcata tgctgcttgt
     5401 cttggatcag tacaggcctt aaatccatca accgtcgtag gttgtactac gcccatccat
     5461 tgtccatttg taaatgtcca aataagcaat cgaacttgtg catctaagct cgttattggt
     5521 tctttaatac ctgcagcatt aaataagttt tgaacataaa cttttccatc ccatgttgct
     5581 ggaccaacaa gaggatatga agaaccatcc cactgaacta atccgtatgc tggtccacct
     5641 atttgaacag tatcaggatc aaaagttcct cctgtttctt gttgaatgtt ccccaatatt
     5701 ccacatgcag attgtttcgt aaatccgtta ttacacaaaa tatcgtatat tctccaagct
     5761 ctcttttctg catctgtttt taattcatca ggatacccac caggtgtttc tcctccgcca
     5821 gatggaccgc cattttgtcc tggtatcact tctttacctc taacagtaag ttttccctga
     5881 atatctaaat caccgaaata atatgctttt ccgtttccta ataacacaaa tcctttttct
     5941 gcagttggag aaattaaaat gtattttcca tcgccatttg tacgtattac caaagaattt
     6001 tcctcaagag gtgtaggtgt tacagcattt ggaaatggat ttcctgctga atctgttgtt
     6061 ccgatcgttc caatggattc ttttctattc cagaattcca tacctttttt ggttagctcc
     6121 atgatttttt tgttttcatt ccaaatttga agcgtgcctt ttacaagttt taacacatca
     6181 ccataagcat taaaggaagt ttcgaatact tctgcattta ttgttcctac tttgatgaag
     6241 tcagcaacaa tttctccttt tgatgtgata gcaataccga acgggccatt tactccgttg
     6301 tctgaataac ctaagccatt taaattccaa cgccacactc gctttgcatt cgccacattt
     6361 ggagtatcca tgataagaat ctctgatgga gctttttctg gacgaaaaac gacatgccca
     6421 ccagaattac cagtgatcca tgccgtcgca ttcaacacat tttgaactaa cgtttctgtt
     6481 cgattgtcga ttttcttttt caattcttgt gcttgagtat ttactgccga agtgtacagt
     6541 gataaatcat tacctaaaac aatatcctta tatttcccaa gcgttgggaa ataagtgtat
     6601 tcgaccatac gctcttttat ctcgatatct agctctttcg ccctaacatg agcgacatca
     6661 ccaaagtgta aagacgctag ctcttgatac atgtcaccgt attcgagtgt gtgttccaac
     6721 gccaccatac tgactgtatg agtagctttt ggctcatgga tacgatcatt gtcaaataag
     6781 gttttgcccc atttgatcaa ttcatcaact gttttacaat ctccgttttc acgtttggca
     6841 atacgtcgat tctcgttggt tactccatca atttctaaat aaccatattc gataggttct
     6901 ttgtcttcat cataatcgtt atcaggaaca ccgccaacca aatacaaact attgacaatt
     6961 gattcttcat caatttcttc ttcgattgct tctaaattga tgccaaaatc aatccgaaaa
     7021 ccattatctg atccaatctg ttttaccagt ttcaaatcat agttatccat atcaagttcc
     7081 gcgctagtca cgccagtcaa attttgatta ccgttatttg aaccaatgat tgcttcaact
     7141 ggcgcgactt gtcttgctgt aaattggtgc gttgtcccta cattcgaaag atagttaaat
     7201 ttttgatcaa atgccaaact gtttttaaga ttggtcatga tctgagaccc attgccgtta
     7261 tccgtaaacg acttgacaat aaagttctta ttggccataa aaccaatatg ccgagctgtt
     7321 acagaaacgg aggtcaaatt ctttttgaca ttataaattt caaaatattg ccatgatcca
     7381 tctggtacct tcgcttttat aaaatttcct ttttttaaat aagagcgata ctgtccgctt
     7441 cttgaatagt taccataaaa acgatattgg ccattcagca cacgattgat ttctggcaaa
     7501 tcttcccaat caactaacga cgctccgttc acgctcaaat catctggcat ttttttataa
     7561 gcataaataa attcttgcgt cacagataca cactcctatt ccaaaaccgc acttctttaa
     7621 attttccgga tatttttacc tgattccatt caggctgcaa tactggccaa tcaccacgcg
     7681 taaataaatt caaaccttct tgtattgctt ttccaagctg agtatcaacc acgattgttg
     7741 cagctaacgt attaagtatt gttaggcttt tatcaccgac agcgatcgtt atatctcctc
     7801 cgttcgattc tatttccaga tagggatgtg caatttcgtc accatgatca aaaatatcca
     7861 taacactaga atgaaaaatt ttaggtgctt caccgatttt tcttttgagt ggctgacaac
     7921 gaaaagtaac atcgaatgta taaaagaagc cccactcgtt ttcgaaaggg acttctttat
     7981 ccatgctgca gatagcctct agatacttgt ctggatcatt atgtgtgatt aattggcttt
     8041 taccagtgag ccatcgtttg acttctctca gtttcgaatg tggaatagtg atcccttcta
     8101 tttccaaatc aaaaggttca tagtcatcaa acgtctccgt caattctccg cttcggccct
     8161 gaatcgtgta agtttcgtat cgcttgttcg gcataatatc tggaagctct gcctcaatga
     8221 tgcaattcat atcaattact gcattccgat ttttccaaat aaaatttggt tcatctggat
     8281 tcataaattg tcgactcaaa taggaacacc tcccaaatca cgaatagcct gtttgtttgc
     8341 tttagcaaat ttacgattca tacgatctaa ctcagatgga ttgtttgcat cgactttgcc
     8401 aatgtgtata tgctgttcaa tgctacctcc agaaactctt ccactgatcc ctttgcgttt
     8461 ttcttcgtct gataatggag taactgtggt tttaccattc ttggcagtca gtaactcagg
     8521 tccagcttca ccaacaatcg cttgtccatt gattagatga ccgccttgtg ctaaataagg
     8581 cagttttgaa atagaaaatg attttccacc tacaccagga acccattttg gtatctttat
     8641 attattcaat ccaccaataa atccattgat caatccaatc atggcattaa taggagcttt
     8701 ccctacagca acaataccat cgaaaatacc tccaaaaata tcaactagac cttgccatgc
     8761 ttttgaccaa ttccctgtaa atactccagt gataaaatct agaaaaccac tgaaaattcg
     8821 ttttccagca ttataaaaat tattgaaatt tgctataaca ccatcgaaaa atccaccaaa
     8881 ataaccactt aaaaaattaa atatttcaac agctacatct gaaacacctt tgaagaaaga
     8941 attcactcca tcatgaaacc atttaacgtt attatatgcc caaattagtc cagtaactaa
     9001 tgcgccaata gctataactg ctaatgcaaa ccagcctccc gacattccaa ataaaccagc
     9061 aagtccttgc caaactccta taaaactttt aacttcccca acgatttttg taacagatcc
     9121 cataagtgaa ccaagaacga ttagtactgg tccaactgct gccgctatac cagcaattgt
     9181 tatgatccaa ttctttgtat cttgatctag agacccccac catttagaga attcctgtaa
     9241 taaggaagtt gctttttcaa aaaaaggcaa aaggcttact tggactgctt cacctacgtc
     9301 agccattgct aattttgcat tgttcatagc ttgatcggct tgatcaattg ggtcgagagt
     9361 agcatcgaat gtgtctccta cagctccccc actttctcca gcagtttttg ctaaatcttc
     9421 caggttcaaa gtacctctac gaattgcatc ggccattcta ggaccgcctt tagtcccgaa
     9481 tacttctgct gctgcattga tggcttctgt ttcagaacct gcatttttta ccttgtcttg
     9541 tagttcttct agtccttgac ttaaagattt tccgtctttc gcataagcca ctgttgcttt
     9601 agataaacta cttaaagctg cgcttgaatc aacaccagat tgctcaaatt gtccaagtaa
     9661 agtgacccct tcaccaaagc tcaaccctaa ttgtttaatt tgtggtgcgc catcaattgc
     9721 tttttgcatc aagtcgtcta cagattgacc agtattctgc gatgttttcg ttgttacatc
     9781 aaggacagaa ttcaaatcat catattctag tccataagca tcaatagctt gtcgagcaga
     9841 tattgctgat tgcgaaacat ctgtatcatt gatttcagcg tactgtagga gataattggt
     9901 tgaatcttcc agttttttat ccatgaatcc aaattgtgta tttacctcac caatagcttc
     9961 cccaaccgtt tgtaaaggta aatgagtatt tgaaccaacg tttttgaaag actgtgaaag
    10021 tctatcagct tgatcacctg ttgctccggt ttttgtaatg atggtatcaa gtgcctcgtc
    10081 aacttcacca aatgctgcaa gtcctgctgc tcctgccgct acaataggcg cggttactcc
    10141 aacagacatt ttttcaccaa cgccttttac tttctcacct gtttcttcga ttttctggag
    10201 tttttttgct gtatcaacag aaacgtcacc ttgttcttta agtgcatcgt tcgtctgttc
    10261 taatgctgta cgaagtttat tttctccggt ttcagaattg agtaattgtt tataaagttt
    10321 ttctgattca gcagaatatt caccggtttc tttgacagat ttttcatatt cctctctcag
    10381 catttgagat cgttgttcag ccaatcctaa ttgtttttct aatttttgtt tagccgctcg
    10441 caatttttct gtttgagttg catccttgtc catcgcagac acttggtttt tgtactcggc
    10501 agcggctaag ttcatttctt tgttgatttc tttgattgtt ttcgaataac tgacttcgcc
    10561 attcgtttta aaattaagaa cgacatcaga ttctttacca gccatttatc ttagcgctcc
    10621 tttctaccac caaggcgatt tatccatagt tacagattga ggtggttcaa aatcggtgtt
    10681 ttgttgtaac cactgtaaat aagatttgag ccacaagtta ggtgtagact ttaaaaagaa
    10741 actctcactc caattcaata gagtgagagc aacgtaaata taaaaactcc aaggagttcc
    10801 tatctcttcc gattcttttt gtttttcttt ctttttgctt gcgctttttg aaagtcttgt
    10861 ggcttcttgg atttttttag gtcttccacc tgaaatgtct ggctagcaaa aatttccata
    10921 caggtactat aagcagacaa cacctctcca ctcattccca aaaatttgaa aatagtttct
    10981 ggatcttcct ctaaaccacc agtacgcagc atggcataaa tcaaggcacg catgattttt
    11041 agatcactag gcgataagtt agcagaagaa atttgtcctt cttttttaga tagcatggcg
    11101 ttcatatcag attcaaattg cgaataatct ccaccataca catctgctat aaattccatc
    11161 gtttgcatag taaatgaaat agggaattct gcgccttgaa taattacaac agcagaattt
    11221 tttaagtctt caacgtgaat tccataatca gataaccgag ccattaaccc gcacctccaa
    11281 ctttagccaa tgttttccac tgttcttcat cgtatacagg ttgagcaatg aatttattaa
    11341 ataattctag agaagctccg tctctatttg aatcaaaact tgcatacatc acattattgt
    11401 atttcagtcc gatggaaacc agatttgcag ttacatcgtc aatttttgtt tcttcctctg
    11461 cagtggcata ctcttcgtca atcacattgg atagttgtgt attaggatac caaactgctt
    11521 ttttaccgcc attttcaata tttccaataa atccaaaggc gaagtacgga aattctcgtg
    11581 cggtattttt gctaaacgtt actccgcttt tagcaactaa tcctttgatt tcatccatca
    11641 cttctatcgg aatacccacg tgatccaacg caagttcatg ttttgtttct cgcgacacac
    11701 gacgaaacat tttgctggat gcccattttt ctaatgctgt tccattccct ttgacaccga
    11761 tttttgtggc aattggcaat cgtaaaactt cactataagt cggtgcagtt ccaacagaat
    11821 ctggcgttgc catcatcgca attaaaatgt cgtccaatcc ttcaaaataa aaagtatctt
    11881 gttttcccaa ttaaaatcac ccttcccata aatcaagtat ttttctagtc ataatttctt
    11941 caattttttc tttgttttgt tcatacgtac cacttgcaaa atgttgggca cgttgatttg
    12001 ttgtgccatt ttcggcaaag cgccagtaaa aggccgtctc ttcaaattga actttcactt
    12061 gatcgttttc aactactact tttatttgat cgcgcatatg tttctttttt aagagcgact
    12121 taggaatatt aggaagcaac tgctttagat aaaagttagc tgcttcttct aaagattcca
    12181 acgataattt tttcggatca acttttgaaa ggtttcctaa ataatccgat atttcagaaa
    12241 aaccattctt attacttggc attttccaca cacctcacat atgtgtaata gttggttacg
    12301 gtatcgtcgt tctcatcacc ttgtatacct gtaaaatctg aatatggaat gccagcattt
    12361 tgcagcgctt gttcaataac aactaaatcc tgttctgttc caagtgtaaa aaaagagact
    12421 tggtaataag gtaatttttt atagacttta ccggatgcca tttttttgct gttactcaca
    12481 tttgagtaca caatgtatgg atacatcgtc cctaatctgg ctttgtctct gaacactgct
    12541 aactttgttg atttcagcgc tgttttcaat tcatcaaagc taatcgacat aagctaaact
    12601 caactccatt tctcttgcat cgggattcgt ataaatgcga gtaatgttat acgttacaga
    12661 atcaattttg agcgcactta atttctctgt gatggattta tcccatctga ctttaattcg
    12721 tctgacaacg tctgtcttgg cttgctgtga taaatatttt tcttgagaag tcacaccgag
    12781 ttcttcatag aatattagac gcttaaattc gtaaattgta gttggacgat cgtttccgtc
    12841 tgttcctgtt ttgatgtcta gcaattcggc tttccatctg agattattgg tctgtctctt
    12901 cggcattttg aatcgctcct tgcacgataa atggcgtcat ggcattcata gctttgtcga
    12961 gttcatcctc tgaaactcta tattcatagg caatgccggc aaccatcaaa ataagatatt
    13021 cttgttggcc accagttgct gttttgacat aatcttttgc catatttaaa taaaaagaga
    13081 gcaaagaatc atccatgccc tcttcaaaat gaatatgtga tttgaatttt tcctctaaag
    13141 acaattcttt agtttgctct tccatcttaa ccaccaactg gttttgtaat ttcgtagcga
    13201 tatactgccg gttcaaatgg agaataaacc aattgaccat ctagcaagtt gtaaatttgg
    13261 aatccaattt gatttttacc agagaatttt tcaacaagtt tttgaatttc caaggcacca
    13321 ataacttctt gaattttaaa tgcagaaaaa tcgccaaaat ataaaactgg cgtgtctggt
    13381 tcaccctttt tatctgctgc atctgtccaa tccacaggat agccaactaa ttggtaacca
    13441 attccacctt ctgcttgtgt gaatggccgc aacaaaggaa atccatcatc tgttttcatt
    13501 ttttcaatgg cagtcaaagc agctcgatta ataataaagc gtcccttttt catcacttct
    13561 gtcactggtg tatttttaaa ttcgattaat gcatcatata atttttgccc agcacctgaa
    13621 gcagttagat ctaaaggttt tttaaatgct acagcctttt tggctaatgc accaggattt
    13681 tcatttccag cgtcatcacc attgaacata taattgattt ctttacgcac ataagctttt
    13741 ttcaattctt ccacaacaat atcttcaact ggaacaccag acatttttaa taatttttta
    13801 gttactgttg ccaaagcatc gaattcggca ggattaagca aaatttcatc aaactgaata
    13861 gctgtttcag caatatcagt tgaacgctct ttcttgttta cattcgcatc tgctttcttc
    13921 acaagaattg gatatttgac atctcctgat gttcgcacca ctgttccgta tttacgaagt
    13981 aaattttctt cttgagcata agtaataact tcagatgcaa ttacttctgg gacagtaact
    14041 gaaccgttgc cagcttcaat ccctaaagct cgagcttctg cttcagaaat atttccagct
    14101 acaaaattag caaatgcttt tcgtagttgt tgatcttttt gtttcttggt catttttgca
    14161 cgtgcctcca atccgttctt aattgatcca agtaatccat ctcgttgctg ttgagtaatc
    14221 attccagaac gattttctga actatcttca ctgtctgaat cttcttcttg atcgttgtct
    14281 tcaccagaac ggctttcgtc tgaatccgta ctattcgatt gatcatctgt attgtcgtct
    14341 gtttcatcag ttccagaatc tgcgcctaat tcgtctttaa ttccgttcaa ttcatcaata
    14401 acactgtcaa tttcttcttt cacggcttct aaatctgctt cgcgtaattc tcctgattca
    14461 actttttcac gtaattcagt caatcgttgc tcacgacgtg ccttcatttt tttcaataat
    14521 tctttatcca tgtatttttc ctcctacgct tctagcgctt gattaatttt tttgattaat
    14581 ttttttcttt cttcgacgtt tttttctaat tcatcacgac ttcttaatgc agcttctgta
    14641 tcttcgtatg ctggcaaagg cacaatagaa acctcgtata attccacttc atggattgtt
    14701 cgaagcattg gttcagaatt gtagtcccac gtttcttcag tcggcacaaa accaaaacta
    14761 cattggttga tgtctcctcg ttccatagat ttaactaagt cccttgctac cgttgtgtcc
    14821 ggtaaatcaa cttcgaattt caaaccacgt tcatcttctt caaggcgaag ggttccgctt
    14881 ttagtacgtc ctagcacatt ggaccaatcg tgattgaaca aacaacgaac atccgaatta
    14941 ctaattgcct ttgagaatgc accaggaaca atcacttcgc ttaagtcatc ccataaaagt
    15001 gtttgactgt tgaatacagc agcgtagccg ctaatggtcc tcgtatgagt ttcttcatcg
    15061 gaacgtgttg aaagattggt gatgtcaatc gtgcgaattt ccttcttctt catttccatc
    15121 acctcctttc aagtcttgat cattcgttgg taaggaatca tctgttgcat ttttctggcc
    15181 aatcctagat aagtcatttg aaatatagat agcttgtgtt tctggagtat tctgtttagg
    15241 aaaaccaagc atttctgcca cgttatctgg acttgtaatc ccggtacgaa cgatgttgta
    15301 gccaatattt gtttttgttg agtaaggaac aaaatccaaa atattaattt tccattccac
    15361 tctatagcca gaattaggca taaaaaaaag agcggtgtaa tgttcgctct tgtttttcaa
    15421 tattggtttg attgctttgt tgtgcagata catcatcgct ttttcaatat ctgtcttcat
    15481 cagcgattga tacgtatcaa cattgattcc tagaaatttt cctaagtctt ttttgtaaac
    15541 acctaaataa ttcaaaattg ccgcgtcatc aacaggactt tttaatgtct cgatggaata
    15601 tccttttccc aaaggaatca tcttaacaga atgatcactc tcattttgcg ttccttccag
    15661 ttgatccaat atagctttga caatttttgt ttgggcgcta ttatttggat tgatgtgggc
    15721 gtctagttta agcatgaacg caagtaaacc gcctttagta tatttgtccg tcaaaacttt
    15781 ttcagcgctc agaacgcctt ctagagtgtt tcttgcaaga tcaattattc cagcaccttt
    15841 taatgaatca gttccgatgt tcttaatgtg tcgaatcatt tgaccaggta ttttttgacc
    15901 attcatttca aattcttctt gaagtcgttc attgatttta gttgttacac cgtacgccaa
    15961 atgaagctga tccctatccg ttaatgggaa tgtctcacca ttgatcaata aagtatttgt
    16021 ttccaatttg gtaaattcga atcctgtcaa ataatcattg ggactcttca aaatatttag
    16081 taagtgatga tctttgactt cgttgccgtc gggaccaata acaattggtg tggccaatgc
    16141 cacctgatta gatatgtctt gaactaattc ataaacatca gaagattcca tgatagatga
    16201 atccgtcaca tatctttgac cataacgtgt gtagtgtcca aaaatatcct cgatatatcc
    16261 acgtttttcc ataaaagaat agactgcatt cgataaccga tcacgtaatt tcaatttttt
    16321 tcaccgcctt tctatttatc tatagatgga acttaggtaa tcatctaact catctgaatc
    16381 aatatctgtc atttgattca tcgtttcctt atgaccacac aaaaacgcca cgaacccatc
    16441 aatctttttc tttgattgac gtttacttgg cgctttttgt ccattgatgt tagtaattgc
    16501 tacaacgttc aaagtgcaat aaaggaataa tggattatca aattgaattc gtttctcata
    16561 aaacaaccgt tcgacatcgt caaaaggagc attcaatact ttaggatatt gagcaacttc
    16621 aacgcattcc aatcctaagt tttctaattt ctcaacaagt ttgtcactca tcgctggatc
    16681 ataattcact tgctgaatat catataaatt catgcagtcc tctatgtact gcaaaatctg
    16741 atcttgatca atcatttttc cgtcgcaaaa ttcaacgaaa ccttgttcag ccaaatcact
    16801 gtaaggaaca ttatcttctt tttctcgaaa ctctaaatct tcattcggaa taaaataaag
    16861 ttgctttact ttaagaaccg ctttaccatc ttcatcccat gttgggaagt ttaaagatac
    16921 acaggtcaaa tctcgtgtac gtgataaatc taaaccgata taacatggtt cgccacttaa
    16981 atcaccaagt tcttgtgtgg taactaaaca tggctctact tgatcctgtt caaagaaatt
    17041 atccgcgccg ttcacaaata catccaagtg tttcgttaga aattcagctt tggaatgagc
    17101 tgaccgttgc gctgttttaa atgccgattc taaagcagat aaatcgactg atattcccca
    17161 gttaggattg cacatttccc agacttttct atccgtccaa tcataatttt tatttggctc
    17221 atagattaga acaaagtttg aatcattatc atcacgtttc aacacttctt ttgcttcgcg
    17281 atatacacgc attccaacag acgacgaacc tttcccagca gttgagatat taaacatcaa
    17341 tggctgtggt aaagatatct gagcagactt aaaattgtca tactgttcca ttttctcctg
    17401 tttatgcaat tcatcgttca atacaaaata tggattggat ccctcgatat tatcaatatt
    17461 cttggtttga acaataaatt tatttgagta agccatatct tcatgaatat agtcataagt
    17521 aatactagaa acagttccct ttggccccct aaatatttta gttccttcaa gtaggattgg
    17581 attgtttaag attgtaactg caaaaggttt ggcagcatat tgcgcttgag caaaatcaga
    17641 tgcgcaagca tagcaatcaa ctgataacgc cccttctccg tacattgcat atcctaatga
    17701 accgacagca atcaatgttt taccattctt ttttggaatc tggacataag cctcacgagt
    17761 aacgcgtaca atttggcctt tttcattttc tttaacccaa ccataaatcc aagaataaat
    17821 aaatttttcc cagggttcta aaagaaacgg ttttcccacc atttctcctt ttgtgtgaac
    17881 aataaatgat tctacccaat ccatcatttc attcgcgcga tctacatcaa accaaatatc
    17941 ttttcttttt ttccactgat accagcgatc tattgctaaa cgaacggtct taggatactt
    18001 cttaggtttc tttcttactt cttttgcaaa taaatcagca taatttacac caggttcaat
    18061 catttttcag cacctgcctt cttacgccat ttatttctgt gcgctgctag ttcatctact
    18121 ggctttactt ctgggcgtgt aatttcttca tcttttcttg cggtcgatcc tccagcaatt
    18181 agtctaccag tttttgcttt gtttgttaat cctaataaat ctagagcttt catcttctta
    18241 tctgcccaag tttctacttg ttgtgccaat ggatgttttg attgattagt agctcctgat
    18301 ttattcgtga atttttgcgt ctccggaaat cctttttcct tccacaataa atatttgtgt
    18361 tggtaaattt caaaaatatc caagtatgat tcgattaatg gatcaagagt gatggtgtac
    18421 aaatcagaca aattcattat ttctaagata cgagcttttt cagcacttac tttttcatca
    18481 ataatcgctt tacgttgcgc tttagtcgtc atttttgtat acacccccct ttgttttttg
    18541 aaaaatttga cctaacgatg cgcgtgactc cccgctaccc tatctcccca cgcgaaaaaa
    18601 ttttgaaaat gaataggggg gcttcaattg aaatacgaag gaaaaacttt tttgtcttcc
    18661 gtttcgtttt caacaattgg atgacatttt gaacataata gcatgagatt gtttggatca
    18721 agcttaagca gttcgttgtc tttgattggt acaatgtgat ggacgtgtgc tctctttcca
    18781 aatatgaact gaccacaccg ctgacaatga ccaccttctc tttcataaat aaattgacgc
    18841 atatctttcc atgcttgcgt tcgatagaat ggtttgttct catgatgata aacagacttt
    18901 gcttgctgct tcttcttgcg tgatctgctt gatctcttgt gttcagtaca gtagataccc
    18961 tttgctattt tgttcgtgca tccgtcaaac tgacagtatt tcattctact tcacgaataa
    19021 gatttatgat atcgcctttt gcacggatag caccaggaat atcaatacca tgtttcttag
    19081 catatgcacg caattctttt gcagtcatat tgtccagttc atccgtatct tcagtggact
    19141 gatcattagt agcttcgtct ccatcaaaat tagcagcagt gtttccatcg ctatcaagaa
    19201 tttcactgct atgagctatg agttcgccat tgacagcaac aaatgatttg ccatcactca
    19261 aaattccttt ttcttctttt acttcaaaat ttggttcttg atctttcgga acaactactg
    19321 tccttttctt ttctgaatcc caatactctg ttccactaat ggatgttcta attttgatca
    19381 ttgccatttt aattctctcc tttgtaattt gtacggatta cttttgcgcc cattcgctca
    19441 taccattcaa tcgtttcctg cagattgggt agagtgtgtg acaataaaga aataactaac
    19501 gtattcattc cagttctgta atcatcattc tccacttgca catgtgcatg attaccattc
    19561 caattttctc tgtacggact attctctgct tcaattgctt tcttataaac tttagccaaa
    19621 cttgattcta cttcaatact aagtaccgct tcatgaaaat cattcatttg tttactctcc
    19681 tatcagatat tttgtggtat gatttataaa aaagatgcga ggtgttttaa tgcttcaaga
    19741 agttaatatt aagtatcgtg atcgtcaaaa tacagagaca atttatttgc caaatagttg
    19801 tccgcattgc ggaaatataa tgactccgta tgtgtatttt ggggtttcat catatagtgc
    19861 gttcgataat gatagaatct ttggcgtatt agtacagtgt ataaatgatg agtgcaacaa
    19921 attttatagt ttacaattta taaatacgtt taatgaagat gaaggatatt ctgaaaatat
    19981 tttaattaaa gattattacc gtccgccgat taaaatagat ttaccagaaa atattgaaaa
    20041 agtttctcct acatttgttg atatttatac tcaagccaca caagctaaat ctgagcaatt
    20101 ggaacaaatt gctggagttg gttatagaaa agctctagaa tttctaatta aagattatgc
    20161 aatatctaaa aattcagagg atgaagataa aataaaaaaa atgttattag gtaaaacaat
    20221 tgaaaattat ttgaatgatt ttcctaaact ccaaagatta gccaaagctg ctacttggat
    20281 tggtaatgat gaaacgcact atgttcgtag acatactaat aaagatgttc atgatatgga
    20341 tgcatttatt aaatcagcag cgcaatttat cgcggctgat tatgatgctg atttagctga
    20401 tcaatttata aatggaaata actttatgcc aactactaat taaaagaata aaagagccac
    20461 agataccaat taataaaacg gttgggatat cttggctctt tcatattttt ttgacactaa
    20521 tagaatatca tgctgctaac aatgtttaca tagctacaat gaccgaacat ttagtgaaca
    20581 gtgtaatttt agaataaaga gagttgttct ttgtacttct cgctattgta aaaatcaatt
    20641 tcgttttctt ttttcaatcg gtcagcttgt ctgtgttcat actcatctaa aaagttcaat
    20701 gtctttctaa tttctgcatg tcgctgtctg acatacgatg agctataccc aacagattca
    20761 gcaatatctt ctaagctcat ttgatcaaca tatttcatct taacaatttg attatcgata
    20821 ccagaaaagc tatctatcag caataacatt tcttcttttt gctcgatcaa caattccaat
    20881 tcattttcta tcttttggat attctcttct aaagaagaag ttctcgaatt cttttcgatg
    20941 cggacgtttg ctaaatcacc acagacccat cgattcaatt caagcttact tttattaaga
    21001 ttccacttta agtaaagaat ctgctcatct agttcttggt aatcttttaa ccaatgaaat
    21061 ctcacaaacg ccacccctta tggtagaata gtattgcgct gctatctcga aaggggtagc
    21121 ttttttattt tttcttagcc gttccattct ggattgcctt ttgttccaaa cgtcgttttt
    21181 tcttcttaat ctttgatttt gtttttccca tacaattctc ctttccgaaa acacattttg
    21241 ttcgattttt aatactaaat aaaagttggc cagaattttt cgttcgtctt tactcatctt
    21301 tttttgaata agattactag cataaaaata gttagtacca cgaaaatgaa caggtaaatc
    21361 aattacgttc accttcttca tgccagttat cagccactag aatctttgcg ttagtgccgc
    21421 caccgttttc ttttttgtat ttttcaaatg ctttataagc agctgttttt gatttataga
    21481 tttttccgga accgactggg aacatccatg tgccctctgt gatagctaag atgtatactt
    21541 tcatttaatt caccccttta atccccaaca ctacatatcc ggacttctgc atgtaatcag
    21601 taatataagt gatctctgct ttgtatgagt caccagtgta actaaatgtt ggtctcgtta
    21661 gtccaggtaa ttcatgttta atgtattttt tatattcacg tagtattaac tgatcaccaa
    21721 ctttgaagtc acgatcattc ttgcggatct cgaattgttt gcgtccgctc gtcactgctt
    21781 caaaatattc tggtagtatt tttagttcgt ggatcattct gtttcctcct tcaaaattcg
    21841 ctcatcatca aaaagtgaat ctccacaaaa tccttctccc aaatatttat cgttcatgta
    21901 taagtcaacc aaatatttgt gatctgcttc tcgatattca ttaatattaa cgatctttat
    21961 tttgtaaaca ttaccttcgt cgctcactat cttgaattgt tctctgactt tcaccaccgt
    22021 tcctcctctt tttgaaaaaa ttttagtgtt tttgtaagac cccctaaatc agctttttta
    22081 tttgatataa tacttgtatc gattaatcaa atcgaaatta aatttaaaaa ggtgatttat
    22141 catgaatatc aacaatttag taaaactcgt tgaacaacgt tttaaagaat caggattaga
    22201 acaattaaaa aaagataatt ctccagaatt attttctaat tttaccgaag acgacattcc
    22261 tactcttaaa caattaaaat attattctga ttattggacg caaactcgtg agaatgaatt
    22321 aaatttagaa aaactcatta ttaaaaagaa atagcaactc cagcccacac ggctggtttt
    22381 ttagtttcaa cttccctcct tacgggtcaa aatcatcggt tccggcataa tctgatcatc
    22441 ctttagcaac aaatcaggat attttttcct tagcttctta ttgttcgtgt aagttttcaa
    22501 tagccattgg ttggcttcgc ttttgctttc tccagaaaaa taaattttcc ctgtttggat
    22561 gcctgcaagt tgaatcatca ttttcacctc aaatcaaatt ttttctgcta gatggagcaa
    22621 aagcaatccg acatcaagaa tcttttgacc cattatttca gctactttgc tcggcttaac
    22681 tccttgagaa aagagcaagc gtgcttgctc tatctcttcg tgagtccaaa taaatttggc
    22741 ttcctcaagg ataattactg gatcagttgc tctcattgtt cctctggaaa aatgatgtca
    22801 ttcttatgct tggaccaggt atctgcatat ggaacaaagt attgtctagc taattcgatt
    22861 tgatcaatta aagcagtttc tgataattca tggtctgcag caatttcatt catactatcg
    22921 ccttcatcta aacagataag accgttgacg ttatcgattt ttacatttgt gactgcttga
    22981 ctttctccac gctcataata ttctacagtt gatactgata catcagcttc ggagtttaat
    23041 tgcagaatct gttactgccg ggataattta atattctttt cataattcac cttttttcct
    23101 actgacatcg aatatttttc atgttatgat tagccgtgaa aggagagcta tattatgtgt
    23161 ttacacatga tgtccttagc tcattcggtt ctttggaagc ttttttggaa ataactctca
    23221 ggttcttgac gcaaatctca tttattcttt gaaacaaaaa acttccattt tccgagagct
    23281 ttggatcact tcaaaagaga tttgcattta tatttctgtg accttgagtc gcgtaaagaa
    23341 ccttacagca atggcggcaa ttccactttc aggaaaccgc cttttttcat tgatattggt
    23401 ggttagcgga ctacccattt tctttcggca gtgccaaacc acaaatgatc tgtgttgatg
    23461 tttaggtagt tgtataccag ataagctaaa tccaaagtgc ctgcatcttc aagacgacaa
    23521 tattccaaaa attctcccat agctggacat aaaaatcctg gagctatcat atcccaacag
    23581 ttaatagtgc aaagaaattc gtttagcttc tgaacgtttt ctttggtttc acgaattaca
    23641 acatactcca attcttctcc gctggcagag cattccaaaa cttcaaattg attaagaaat
    23701 ggtagaacat atgcttcaaa catcaacatt ccatctttct gtttttgcac ttgttttgca
    23761 tcaatcatgt ctatcctcct attcagttat ttcttccatt aatggaatta tttcaggtca
    23821 ctggacttaa cgaaaacacc attgaccatc tttccagtcc gacctttgat ttcgtcataa
    23881 gcaaaatcca agcactcgta taaatccata tcattttgca ttgccaagat gatcaaggtt
    23941 actactacat cgccaattcc gtctcttaaa ccatgttcat cttttctagc tagagaagcg
    24001 gcaacttccc cgatttcttc gaccgttttt aacatttgct tgctgaaatc cgcttgatcc
    24061 aatcccttat cttttgccca ctgctctact ttcgcgatta gttcgtccat tatttctcct
    24121 ccacatacct aaactgtctt ccttttgaat caatccataa gctcctagct ctatcccaaa
    24181 taatattttt gctcagacca gtaatttcag ataactgttt agcggtaccc gttactagaa
    24241 ttcgatcacc atgccagatt gcaatctttc tcggcgttct ccgtttgggc ttttcagtcc
    24301 acattgattt accgagcttt tggacttctg caactatttt tttatcttcc tgccaatctt
    24361 ctgaataagt caattcgata attcgctgca ttgccgcttt cttatccatc ccgacattct
    24421 cctttcagta atttgagtac ttgatcaagt gcgctctcac gtccgccatg aaatgtgttg
    24481 agccacttgt cttcgtacga cacactttgt cttaaagctt cttgatgcat taattcgatc
    24541 tgtgctgtaa atgtctttag gtccatcttg tttacacctg ctcaagttca ttaagatgtt
    24601 tttgcaagcc tttaacacaa tcaatgaata gtaatttggt atatgctaaa tttcttaatt
    24661 gcgttccatc gatatagagt gcgaaatagt atctgagttt actccaactc gaacgatcat
    24721 tcttaattcc ttcaattcca gcttcttcga gttgatcata tacgtctctc aggacgtcta
    24781 attcctcgcc ctttttataa ttcgctattt cattaattag ttctagataa tcgatcttca
    24841 tttttccacc tcttagaatg gtgcttttga ttgtctatta gctcgttcta gcgctttttt
    24901 cttgagatag gcttcttggt cgattgccca ttcaggaagc ttctctcgtc ttcctgtgcg
    24961 cttgtatcca ctgcttgcgt tcttaggttc acttttttct ttccttgccc aacttcgaat
    25021 agttgccaaa tagtttttat aagtcttacc agatgattca caatactctg acagtcgttc
    25081 gattcgctct tggtaatcat tagggaattc tgttttgagt ttctccatct gctcatctga
    25141 caaaagaaca tttttatact ctccgtattt atgacggacg ggcttagcct tcgatttttt
    25201 cgaaggcggt aactctctta tatattcttt tgtattatta aatgtattat taatagatgt
    25261 attattatct ttgacttttt cgtcaatagg ggtattgcgt ttttcgtcaa tagggtattg
    25321 attaattcgt aggtacctat tgattatttg attggtaccc tctttgtaaa tgatttcccg
    25381 attcaagtat ccaaacttaa tcaaatcact tacccatcgc gatatggtct ctttattcac
    25441 accatataaa tctgcaaagt actcattgcc tgcccaacaa aagcctcttt cattacacaa
    25501 ggccgttatc tctccgtata acaacttagt atttggttta agtcttttgt cgtaccttac
    25561 gttggctggt ataatcgcat aataacttcg atgttctgtc atttttcccc tccaatattt
    25621 aactttttga ttgttttctg gtttaatttg atccctttga tttgatattt atttttgaaa
    25681 ttaatcacac ctattttgtg cttctctgtg tgatggattc tgcagagtgc tgcaaatgtg
    25741 tactctgcat gatcaacttc tttgcgcttt cgtcttccta gcgctttgtc aaagtgatcg
    25801 atgtcagctc ctgttttgcc acagatgcag cagactcttt ttgtgatgca tttgtagaag
    25861 taatattctt gattcgcagg taaaatctca tagccttctt tgaaaggaat atgatgttca
    25921 aagatgaaat ctaagatgat atttgctaag acattggcat cactcacagt tgtattcgat
    25981 tcgtctttca ggcttatttt gcgccctgtg acaccttcaa aacgaaagta gaagaattcc
    26041 ttccagaagt ccgttggcat gcctgtatcg ataaaaatat cgcctatcag cgcatagatg
    26101 aagtttcgtt gctgtacggt gaaacgtcta ggatcaataa aacgaatttc aatgactcga
    26161 tcaccatcgt agccgtcata catcgtcttt agtcgatcaa tgttcacttc ctcattgatg
    26221 gttgcgc
//
LOCUS       DBBGRF010000040        26164 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000040 DBBGRF010000000
VERSION     DBBGRF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.040"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(66..1097)
                     /gene="queA"
                     /locus_tag="ACIZD4_001916"
     CDS             complement(66..1097)
                     /gene="queA"
                     /locus_tag="ACIZD4_001916"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGC5990828.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1290..2465
                     /locus_tag="ACIZD4_001917"
     CDS             1290..2465
                     /locus_tag="ACIZD4_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HGC5990829.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2469..3110
                     /locus_tag="ACIZD4_001918"
     CDS             2469..3110
                     /locus_tag="ACIZD4_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990830.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3107..4024
                     /locus_tag="ACIZD4_001919"
     CDS             3107..4024
                     /locus_tag="ACIZD4_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC5990831.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4021..4692
                     /locus_tag="ACIZD4_001920"
     CDS             4021..4692
                     /locus_tag="ACIZD4_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990832.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5233..5721)
                     /locus_tag="ACIZD4_001921"
     CDS             complement(5233..5721)
                     /locus_tag="ACIZD4_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HGC5990833.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5922..6188)
                     /locus_tag="ACIZD4_001922"
     CDS             complement(5922..6188)
                     /locus_tag="ACIZD4_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGC5990834.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6188..6451)
                     /locus_tag="ACIZD4_001923"
     CDS             complement(6188..6451)
                     /locus_tag="ACIZD4_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC5990835.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6972..7112
                     /locus_tag="ACIZD4_001924"
                     /pseudo
     CDS             6972..7112
                     /locus_tag="ACIZD4_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(7254..9077)
                     /locus_tag="ACIZD4_001925"
     CDS             complement(7254..9077)
                     /locus_tag="ACIZD4_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC5990836.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9675..12380)
                     /locus_tag="ACIZD4_001926"
     CDS             complement(9675..12380)
                     /locus_tag="ACIZD4_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HGC5990837.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12686..13633)
                     /locus_tag="ACIZD4_001927"
     CDS             complement(12686..13633)
                     /locus_tag="ACIZD4_001927"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HGC5990838.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13823..14092
                     /gene="rpsN"
                     /locus_tag="ACIZD4_001928"
     CDS             13823..14092
                     /gene="rpsN"
                     /locus_tag="ACIZD4_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGC5990839.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14268..14630)
                     /locus_tag="ACIZD4_001929"
     CDS             complement(14268..14630)
                     /locus_tag="ACIZD4_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC5990840.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14641..15762)
                     /gene="alr"
                     /locus_tag="ACIZD4_001930"
     CDS             complement(14641..15762)
                     /gene="alr"
                     /locus_tag="ACIZD4_001930"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGC5990841.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15778..16128)
                     /gene="acpS"
                     /locus_tag="ACIZD4_001931"
     CDS             complement(15778..16128)
                     /gene="acpS"
                     /locus_tag="ACIZD4_001931"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGC5990842.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16258..17769)
                     /locus_tag="ACIZD4_001932"
     CDS             complement(16258..17769)
                     /locus_tag="ACIZD4_001932"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGC5990843.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18091..19443)
                     /gene="murF"
                     /locus_tag="ACIZD4_001933"
     CDS             complement(18091..19443)
                     /gene="murF"
                     /locus_tag="ACIZD4_001933"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGC5990844.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19596..20672)
                     /locus_tag="ACIZD4_001934"
     CDS             complement(19596..20672)
                     /locus_tag="ACIZD4_001934"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGC5990845.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20868..22613
                     /locus_tag="ACIZD4_001935"
     CDS             20868..22613
                     /locus_tag="ACIZD4_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HGC5990846.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22893..23330)
                     /locus_tag="ACIZD4_001936"
     CDS             complement(22893..23330)
                     /locus_tag="ACIZD4_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HGC5990847.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23314..24687)
                     /locus_tag="ACIZD4_001937"
     CDS             complement(23314..24687)
                     /locus_tag="ACIZD4_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990848.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25009..25497)
                     /locus_tag="ACIZD4_001938"
     CDS             complement(25009..25497)
                     /locus_tag="ACIZD4_001938"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5990849.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25519..26121)
                     /locus_tag="ACIZD4_001939"
     CDS             complement(25519..26121)
                     /locus_tag="ACIZD4_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGC5990850.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5561 c         4838 g         8262 t
ORIGIN      
        1 ttttctttgt cataaaatct ttgtaaagct tttttgttat tcaaaactag cggcttttca
       61 taaccttatt tcacgaacat cgcatctcca aaactaaaga aacgatagcg ctcttcaatc
      121 gcatgctggt aagcagataa agtcaattct cttcctgcaa aggcactaac taacatgact
      181 aaagtcgatt ttggcaaatg gaaattagtt gagaaagctt ctaccacttt gaattcatag
      241 ccaggcgtaa tgaaaatatc agtccatccg ctgtctgctt tgatttctcc attaaatttc
      301 gttccaatcg tttctaatgt tcgaattgaa gttgttccga cagccacgat tttcccgcca
      361 tttttacgta cttggttcaa tcgctcagcc gcttcttccg tcaaacggta gaattcacta
      421 tgcatatggt gttcttcaat tttatctacg ctgacaggtc ggaatgtacc taaccctaca
      481 tgtagtgtca gatagactaa ttcaacaccc tttgcttcga tctcatcaag taattctttc
      541 gtaaaatgca atccagctgt tggcgctgca gcagaaccat tttctttcgc atagacagtt
      601 tgatagcgat ctgggtcttc cagacgttct ttgatatatg gaggcaatgg catttctccc
      661 aatgattcaa gaatctctag aaaaattcct tcatactcaa agtcaatgat ccgtccgccg
      721 tgttccaatt cttctttcac tactgcttgc aatctgccat caccaaaaga gattcttgtc
      781 ccaactttgg cacgtttcgc aggtttgatc aatgtctccc acgtatctcc ttgtgtattc
      841 gttagaagaa ggacttctaa atgcgcacca gtatctggtt tttctccata taaacgagca
      901 ggcagaactc gtgtattatt cataactagc gcatcaccag gctgtaactc ttcaatgatt
      961 tcatggaaat gtttatcttc catctctcca gttttccgat ccaaaacaag taaacgagaa
     1021 tgatcgcggt cttttaatgg tgtttgtgcg attaattctt ccggcaagtc aaaatcaaaa
     1081 tcttctgttg ttaacatatc gtcactcact ttctatcatg tgcttcatca ttctatcatg
     1141 tttttcgttc tgttggcaaa atcagcactt tttcacttct attttttgtt ttcctaaata
     1201 aaaaaactac cctatttgta ttttttcatt gttttaggca tactagtaat agatagttct
     1261 tcattgaaaa tagaaaaaga ggtggcacca tgattgaatt tcaaaatgtg tcaaaaattt
     1321 ataaaggtgg aaaagtcgct gtagaggacg tcaatctttc atttgaaaag ggtgagttca
     1381 tttgttttat cggtacgagc ggaagcggaa aaacgacgac gatgcggatg atcaaccgaa
     1441 tgactgatcc aacacaaggg aaaattttga ttgatggaaa atccatccaa gaaattgatc
     1501 cagtggaatt gcgacgtcag atcggctatg ttatccaaag tattggattg atgcctcaca
     1561 tgacgatccg tgaaaatatc actcttgtcc aaaaattgtt gaaagtcagt caagaagaac
     1621 ggaataaaac agctgaaaaa atgattgatc ttgtggaatt gccccgtgag atgttagatc
     1681 gctacccaca tgaattatct ggtggtcagc agcagcgtat tggagtcgtt cgtgcccttg
     1741 cagcgaatca agatatcatc ttgatggacg agccattcgg tgcgcttgat ccaatcactc
     1801 gtgattcctt gcaagacctt gtcaaagatt tacaagagcg tttgggaaaa acgatcgtat
     1861 ttgtaaccca tgacatggat gaagcgatta aactagcaag ccgtatcgcc atcatgagtg
     1921 aaggccgtgt gatccaattt gatacaccag aaaatatttt acgtcatcct gcaaacgatt
     1981 tcgtagaaga gttgattgga gaagatcgcc tactacaagc caagccaaat gcgacaagag
     2041 tcggcgaagt tatgctaaat acagcaatca cgattacacc ggaaaaatca ttacaagaag
     2101 caatcaaact gatgagggaa aaacgtgtag atacgttgtt agttaccgat aattcgaatg
     2161 tattaaaagg atttatcgat gtagaaacgt tgaataaaaa acgaggaaaa gtatccagtg
     2221 tcggcgacat tttgaataaa catgtttttt acgtaaaaga atccgcctat cttcgtgata
     2281 ccttgcaacg cattttaaaa cgcgggctga aatacgtgcc ggtcgttgat gaacagaaca
     2341 aagtcgtagg tatcctgact cgtgcatcat tagtggatat cgtctacgat gtgatttggg
     2401 gagaagatcc cgcaactact gatgttgcag agtcagctac tcctgaagaa tctaaggagg
     2461 tctgacctat gcagcagttt tttcatcagc acggttcaga aattctctca aaaggttttg
     2521 aacatcttta tatttcagga cttgctttga tcattggtat catcattgct gtaccgcttg
     2581 gtgtcttact gacacgtttt ccaaaagctg ccacgattgt gattggctta accagtgcct
     2641 tgcagacaat cccttctctt gctttattgg cattgatgat cccgctattt ggcgtaggta
     2701 aattacctgc gattatcgca ctctttattt attcattatt gccgatttta cgtaatacgt
     2761 acattgggat gaaaaatgtc gattggaatt atcgggatgt ggcaaaaggc atggggatga
     2821 ctgagttcca atccattttt tccgttgaat tgcccattgc tatgccaacg atcatggctg
     2881 gtattcgttt agctgccgtt tacgtgattg catgggctac acttgcctct tatatcggcg
     2941 ctggtggttt aggcgatttg atttttagtg gactgaataa ttaccaacca gatctcattt
     3001 tggcaggtac gatccctgta acaattttag cactattggc tgattggctt ctaggtctct
     3061 tggaacaccg gctgacaccg atcgcactta gagaggagaa tgaagaatga aacgtatact
     3121 aaaaatgacc atggttcttt tctctcttct tatacttgcg agttgttcct tccctggtct
     3181 tgccagcaat acagatgaag acaccatttc gatcacaggt ggaatcactt cagaagcaca
     3241 gatcttagca agtctagttg ccggaatggt tgaacattat acagataaaa ataccgcaat
     3301 catcaacaat ctggctacta caactatcaa ccatcaagcg atgatgaacg gagatgcttc
     3361 aatttcagcg gctcgctaca caggaacaga tttaacgact acattgaacc ttcctcctga
     3421 aaaagatccg aaaaaagcgt ttgctaccgt gaaagatgaa tttgagaaaa gatacggtca
     3481 aacgtggttc ccgtcctatg gttttgaaaa tacgtatgtc tttcttgttc gaaaagacac
     3541 cgcacaaaaa taccatctat ctaaagtcag cgatctgaaa aatgtagcgg atgaattagt
     3601 agctggtgta gatacttctt ggatcaatcg taaaggagac ggttatgacg gcttccaaga
     3661 aacttatggc ttctccttca attcgatatt acctatgcag attggacttg tttatgacgc
     3721 agtcgaagca ggaaaaatgg atattgttct tggctactct acggatggac ggatcgccag
     3781 ttatgatcta gtcatgttgg aagatgatcg tcaattcttc ccaccatatg atgctgctcc
     3841 agttgtagac aacaagatat tagctgatac gcctcattta aaagaagcct taaataagtt
     3901 aggtcatacc atcagtacgg aaaaaatgca ggaattgaac tacgaagcag ataataatct
     3961 agtggaacca tcagtagtag cacaacgttt cttacaagaa aaccactatt ttgaagggaa
     4021 gtgaagcaat tggataaaat gaatgtcttt caacaatttt tctattattt ccaggaaaat
     4081 ggctcctata tctttgcaca atttatccgt cacttcctga tttctatcta tggtgtcctc
     4141 tttgcagcag ttgtcgggat tccggttggg atcatgattt ctaggagacg taaattagca
     4201 aactgggtga ttcgtttggc gaatatcatc cagacgatcc cttctctagc catgatctcc
     4261 attttaatca ttggattagg cctgggagtc aatgtcgtga ttgttactgt atttttgtat
     4321 tccctcttac cgatcatcaa gaatacgtat accgggatga tccaagtaga caaaaacatc
     4381 cttgatgtcg gcaaaggcat ggggatgact gctagacaac gactattcat ggtagagtta
     4441 ccactctctg tttctgttat catggcaggc ataagaaacg cgttagttgt tgccatcggg
     4501 ataaccgcga tcggtgcatt cgtcggtgct ggtggtcttg gagatatcat tatccgagga
     4561 accaatgcaa cagagggcac atcgattatt ttagcaggtg cattgccaac tgcattaatg
     4621 gcgatcatca cggactggct tttaggtatt ttggaaagac ggctagatcc agccagccgt
     4681 acatcacgct gatgttattg taaaaaacaa aagcttctgc gaccatttgt tggtcgcaaa
     4741 ggctttttta gttctgtcat ttttaaggca ataatccact ctgattcttc cctccttatg
     4801 ggcaaagagt tgcttttctt agctatttat ccattccgta tactccaact tcatactgcc
     4861 aacgggttca tatctgcatc caccgactaa gtttttttct tatccgctaa ggcattttgc
     4921 caatccattt tcccatcact cgtcatggaa ttcataccac atgatctcta aatactcgtc
     4981 tgcttgttct ttgaattggg catcaattct tacatccttt ggcgtggctt tcatttaagc
     5041 cttttccatc agtcctcgat tgttcgatgc cttcagctgc atcatcaaaa ctggtgactg
     5101 ccgtatcggt aacttcgatc atcttttata caatcgggaa cttgccatcc tcatccttgg
     5161 ctaaaaacat atctagccat tccagcttct cgccatggga ggtttgcggt tcctaaaacc
     5221 ggtacacgat tcttatggac tgcatccgtc gcaactagac ttggcgatac gatgatcctt
     5281 caccagaaga gcacccccgt aaaccaattg atcgatatat tgccaataag aaaagacatt
     5341 ggcgtaaaag atatcgatcc ctcgtgatgc attgccgttg atactgctat tcatggccga
     5401 aagcgccacg actttaactt cttccgtttg agtgacattc atgttcggca atgtcgcttt
     5461 ggatacccgc tctgctaaag gaacgacact ggtattgtat ttcgtatctg tatcttttcc
     5521 aaaagaccat gccaacgaat cctctgggaa ccaataagac gactccggtt gattgtccat
     5581 tgcttttttc aacatacttt tggctgtttc tcgataaacg acatttccaa ttgtcttcgc
     5641 ctcactttgg cgataatcga tggtcgttgc cactgccaac actaacaacg atgctccaat
     5701 tttactgatt ttccttgtca cacttcttcc tccttgtttt acataaaccc gtcaacattc
     5761 cattcctaaa ctcaaacaat gacccttcaa aggtggagat ataggaacaa attaaagaaa
     5821 tcatgcaata aatccaagaa ggttggtttt agaacaaaaa aagagtctcc tttttgggga
     5881 gactctttgt taactatcta aaaaggttgg ctcttctcac ttcactcata atgtgtccag
     5941 gcagaataaa tttctacaac tttattttcc tcatcaactt tgtaaaccac tcgatgctgt
     6001 ctattcagcc tgcgtgagta tctgccttca tgtgtaggtc tcagcttttc aaaagactgc
     6061 gtgggcatat atggatcttc cttcaatgtc tgaatcactt cttcaaattg tttctttaaa
     6121 ttcgtttgct tgatttttct taaatccact ttcgcagagt ttttgattgc gactgtatag
     6181 ttactcatca aagagcttcc caatcaatat catcgatatt cgtaaagcta ctgtcgtctt
     6241 tttcgcggtc tcgtacttta tctaaagtac ctgtttgctc aagaaaaagg gtttcttgaa
     6301 tcgctctcca gtcttccagc ccaatcaata cagcattgtt tccactacga tcactaataa
     6361 tctcgatttc agtatgattt tcatttacct ctttcaataa ctgataaaaa tttttacgag
     6421 cagtgctagg attcatcgtt gtattagcca ttgtctctcc tcctttttct gatataatta
     6481 tagcgtactt gattaagtac gtcaaaaaaa tacaataaag cacttaaatt cagcaaactt
     6541 ttcctctttt ttacatagag aaaaagaccc ctttttaggg aggatctttg tccacgctca
     6601 cttcttactc ctttacgact agcggtagcc aaacgtaaag taattggtaa caacgtatca
     6661 tctttagcaa aggtcgaatc caaagcctgt gagtctatgc aacaacacca atacacgaag
     6721 gttcctcgtt gcagtgtgac ttgattgata tcttgaataa cctgaggata cgcacgaaag
     6781 atttgtaacg gttattcaaa actgattttg gccgtcaagt cttctactgc ctcaaaaatg
     6841 attgcctctt tcgtctcctg tcattcatgt tcactatcga tttgatactt gcttagaccg
     6901 ttgggtttgt gaatcaccaa ttaaaaatgg cactgagtta tggtaacaaa aaatggtcac
     6961 ttgacgaggc tgagattcct acttatgaag acacatggca cttaagagtc gaggtaaagg
     7021 aagaagctga aaatatagga ggctgtacat tatttggcaa aggattcgga aattatgatc
     7081 aagacatcaa aatcaaaatg ttttacagct aaataggaag aataataaca tttcatacgc
     7141 tgttcccatc tttaatggct tatagagggc acctttagct gagaataaga caaaacagac
     7201 cctctagctt caattaagag ctagagggtc tgtttttgat tttaaaactt ggtttatttc
     7261 ttcaaatggt agctataggt gctgacaacg atattttcac gccaagacaa tcgcaatctt
     7321 aaccgcaaac ttgtttggtt atggagaata ttctgccagc gtctgtttgg tacaaattga
     7381 ggaatcaaca cagtagttgt atagttttgt ttcgctgcat ttttacttac gatatctaca
     7441 taacggataa ttggattttc aatcgagcga taagaagagt ggacgattga aaaacggaca
     7501 tctgggaaat gctttttaaa ttctgcttcg atttcttttt ctttttcgac atcttcgtct
     7561 agcgaaacat gcatcgcaac gacataatca ccgatcgaac gtgcgtaatt caacgcaccg
     7621 atatttaccc gtgtcacatt cccgactaat acaagaacgg tattcccgtc ataatcatgt
     7681 agttttgcat cattttctaa acgaagctgt tctgctactt ttttataatg atcatggatc
     7741 ttataaaaaa tgaacataac gattggcata atgatgaaga aaggccaaat gtcccctaac
     7801 cgatagacaa acaaaatcgc aatgattgca tatgagatga acgcacccgt aatattggca
     7861 atcgatttgc ttaaccatct ttttccttct tttttccatt tgacgaccat ccctgtttga
     7921 gataaagcaa atggaatgaa cacgccgata gagtataacg gaatcaagcg ttctgttgag
     7981 ccatggaaaa taaacagcaa tacgatcgaa cctagcgcta gtgtgataat cccattggaa
     8041 tagcctagtc gatccccacg atcttgatac atgtgaggca tgaatttatc ttttgccaga
     8101 ttgtatgcaa gaactggaaa agcagaaaaa ccggtgttag cagcaactgc taaaatcagc
     8161 gctgtagcaa attgaaggac gtaatacaaa ataccatgtc caaagacagc tttaccaatt
     8221 tgagacaaaa cagtgacttc tttttcagga acgatcccat accaatagtt gataaatgtg
     8281 atccccacga agaagaaacc taagatcaat gccatcatcg tcaatgtagc agcggcattt
     8341 tttgctcttg gcttcttaaa gaatggtaca gcattactaa tcgcctccac cccagttaaa
     8401 gaggaagaac cagaagaaaa tgctcgtaaa atcaaagcga tagaaacacc cggcacagcc
     8461 gctcctggaa gtgcagtagc ttgcaatggc acagcacctg tcacgatatt atataaacca
     8521 acaacgatca gtaacgagat cacaaggata aatgtgtaca ccggaaataa taggaacgat
     8581 gcagattccc tcagcccacg aagattcagc atcatcagta gcaaaacgat tgtcacagaa
     8641 atagcgactt gatgaccgta gagtgctggc accgctgatg tgatcgcttc agcacctgct
     8701 gagacagata ctgctactgt caacatgtag tcgatcaata aagagccacc ggaaatcaag
     8761 ccagcattct ttccaagatt ctcactgctg acgacatatg ctcccccgcc atgaggataa
     8821 gcatggatga tttgacgata tgatagcgtt aatgaaatca ataaaataat aacaaaagcg
     8881 gcaatgggta gcgaatacca gatggctgca gcagacaaag cgactaaaac gacaacgatt
     8941 tgttccgtac catatgcaat agatgataac gcatcagacg acaataatgc caaagcagca
     9001 aatcgggtta atttgtgctc atcattttca gcagatttta aaggcttacc tactaacaac
     9061 ctttttaagt aatccaattt ctaaactcct ttacacacaa ttttacttca agttttatag
     9121 tcgaaaattt atagtaaaca agatgttata gtacgctcac tgaccttaaa agtcaataaa
     9181 ctttaagaaa ataattggaa aaaaacagaa aaatatcaag cgctttttca aacgctttaa
     9241 tacagcaaaa atctaacatt tttttatggg ctttttcttt gaattctata ataaaaggat
     9301 agaacttgac ttagaaaatc aagttctatc ctttttgata tcttaacttt tggaagagag
     9361 atgtaaggct gctttctacc catcattctt actactcgaa gcatagcgca gttgtcacaa
     9421 cctcttgata aacggtgttt aaaagcttgc atctgcggta ataagcccaa ccaaattaaa
     9481 aacataagaa gctgttttta tttggtcgtt cttattactt gatgcagagc agctttttta
     9541 caacctcttg gtacacggtg ttcaatcagc tgaccctcgg tattagctca aaaaaacggc
     9601 aaaatatgag gaactatttt tccatttttt tctctaatac tcaggtcaaa acactgattt
     9661 cacaacctct ttttttaatg aaaaatatgg ctctcatgcg ccgcttcttt gaatttcgtc
     9721 attttttctt cgatgaacgg atagattgcc gttcctacga ttccaaagac aacaaacaaa
     9781 ccgatcatga tccagattgc tttcgtagca tttggccaat aaattcctcc tgcagattcc
     9841 cgtaacaagt ttaccgcatg agtaaatggc aagaacggat tgatcatttg gaagaatttc
     9901 cctgagactt ggatcggata gttcccgcct ccgccagaga tcgacagtac taagatgata
     9961 atagcgatcc ctttaccgac attatcgaat aatgcagcca agacatagac gatcatcatg
    10021 aacgctaagg cgatcaagac agcaaatgac acgctgtaga ccggattttg gacatctact
    10081 cctagtaaga aaatattccc taatgtaacg atcaagcttt gcgcaatcgc cattgtcaaa
    10141 aatgtcagca tacgagcaac gaattgttct cgtttcgtaa aattgtttcg gtctttcttt
    10201 cctaaatagt attctgtcgt agcaacactt gaaagaagaa cagcgccgac ccacagacat
    10261 agtgcagtat aaaacggggt gctagctgaa ccgttatttg cgattggata aagcgcattg
    10321 gtttgtagct caacaggttg tgtaaagaag tcactttctt ttgttgcgtc tagtttcaat
    10381 aatttgatga cttcgcctag atcgacttct tgttcgcctt ttcggatcgc gtctgctgct
    10441 ttttggatac cagctttgat atttggccag tcattgttga tcaagtccgc agcagcgttc
    10501 acagctgttt cgacttctgg cattttttca tttactgttg tcaatgtacc ggtgatttca
    10561 ttttttagtg ctggccaatc attttggata aaatcagcgg ccaatcctaa tttttgctga
    10621 atgatcggta attcattgtt gtataggtct gccccttcat tgatgccatt gacgatggta
    10681 tccatatttc cattcagcat tgtattggca tcatggattt cttgtccaat tgcaggcatt
    10741 tctttttgat atttttctaa aattgccact gcattcgtta cagttgcttt cgttgagctg
    10801 agaagcgaat caaagtcgat ctggtccgct ttgctcagtg cgccttgtgc agtcccaatc
    10861 gtatcgatga cttggtctag tagagaagtg acagtggaac tgatttgacc tgtattgata
    10921 ccagcaatga tgccattgat attattaaca acggcatcaa tttgatctag caattcatca
    10981 atagccttcg tgtcttcatt ttgaacagct gtgttcaaag cagataggcg gttttgcaga
    11041 ttgcttagca agggttttaa ttgatttagc tgatcaataa ttggctgtaa tttcgtattt
    11101 ccagcacttg tttgcaattt agtcaggaac tcgaccagtt tatcgattgc attttgttgt
    11161 tgagatattc cgtcaataaa gccgttcaat acattgctga tgtttttctt ttcatcatca
    11221 gtcagcttac catcttcaat agctgttctt acagtatcta ttaacgaacc tgtcgttgtt
    11281 gccacttgtc caattgactt caatgtaaca tctacactgt ttgtgatgct tggtatcgca
    11341 tctttcagct gagaggcacc tgattttgtt tggtttgcta gatcacttgc ctgattttct
    11401 aaatttttca catctggcaa gatatcttgt acttgttgga tgatcgtcaa gccttgtttt
    11461 gcttcatcga ttccttggtt cattgtctct tggatcgaag caaaatcgcc gtcgatctct
    11521 gctagttgct taccggcatt ttggatctct gggatttttt cttgcaaatc aaggatgatt
    11581 tttgcttgat ctttcaactc aggcattttg tcattcaatg caacgacttt ttcacccatc
    11641 tcatctactt tagggatgta atccacgaat tcatttgctt tattcagttt ttccttgatt
    11701 tcaggtagtt gactttgtaa ttcgaggact tgttttgtgt agccgtcgat cgtgtccaaa
    11761 ttttcatctg ttgataaaat catatcttta actttattga tacttactag gttcgtatcg
    11821 atgtcgtaac ctatctcatt gaatactttc aataaagtcg aactggctgt tttgataaat
    11881 tcatttgtga tttgcgattg gatcgaactt gctcctttat cggtgatttt cggtgcaatc
    11941 gcattgattt tttcatttac cgtatattcg atttttggtt tcttgatatc accactagta
    12001 aaactcagca gatcttctga gaaatccttt ggcaagtaaa tacctgcgta atactttccg
    12061 gaacggactc cgtcttctaa ttgttctttt gaatcaacga attgccatcc taattgttta
    12121 tttttatgaa gcgattcgat gacttgctcc ccaatggcca cttctttacc ttgaaactct
    12181 gctggcttgt ctgcactgta aacagcaatt ggcagctctc cagtatttcc atatggatcc
    12241 cataatgctt tgatgttaaa ccacgcatat agcgaaggga tgatcatgat cgcgatgatc
    12301 agaagtgttg caatcgggtt tttgaaaatc cgtttccagt caagcaaata taatcgaagc
    12361 gtatttttga ttgactgcat agttctcccc cttcttcttt tttcagctga attactttac
    12421 catgtatttc atactttttt caatcggctt ttttcaaaaa agtcgaattt ttggacatat
    12481 cacggcaatt gtctcattgt aatctcttac atattgagaa ataattaagg attacagcct
    12541 ttactttatc atgaaataaa agggaaagat aattttatgc caaagttttt atctattata
    12601 cgtatacgca aaaaagctaa aacatttttt gtctttgccc ctacaaaaat gtttcagctt
    12661 ttttcgtttt ttattcctgt atttcttatt tttcgaatga caggatgatt ttcccagcag
    12721 gaggatgtcc ttcaactagc tgatgtgctt ggatgacatg cttaagtgaa gcagacagat
    12781 tcattgaaat aaaaacatga aaggctcctt tttggtaggc tttgattatg ccagcaaagg
    12841 cttctgcatc tagatattcc tttcttggaa caaacgattc ataaaagcct tccttttttt
    12901 gccgcaaatc tagatctggg aggtcattta atgcaacata cctgccgcct ggtttcatga
    12961 tctggatgcc ggtttctcct ttgatacttc ctttcgtcgc atcgattaca aggtctgcct
    13021 gatcagcaaa ttgcagacct ggatttgttt tatcataagc agcaaatgct gaagctccta
    13081 atttttttac cttttcctca tttttactgg atgcactggt taagattcgg attccctttt
    13141 catggagaag ctggatcaga cttgacccga ccgcacctga tgctcctagt atcattacag
    13201 tatctgtcgg ctggatttcc gtcaaatggt tgattagatt ataagccgta attcctggcg
    13261 tgaccattcc ggctgcttct tcccaactca ttttatctgg aatttttgct acttttgctg
    13321 atggcaacac gacttcttct ccgtaagtcc cgccgactgc atggacagct actcgatcac
    13381 ctacatgaac agttgtgaca tctgaaccaa tctctgtcac aataccagcg ccatcattac
    13441 ctggtacata agggaatttc aatgttcgta tctctttcat ttctcctaaa cgcaaggcaa
    13501 catcataagg attcacactg aatgctttta tttctacacg aacatgtcca gaaccgactt
    13561 ctctgggatg agcatcgatt tcttcaaaaa catcttgtgc ttctccgtaa ccgttaattg
    13621 caaatcttcg catggtcacc atctcccttt ttctttaagt ttacgtttat gcctttattt
    13681 tgacaaaaaa aatgtctttt cgttttggcg catgattcaa aacaaaatag ttgtcttttt
    13741 tcgcgtaacg tgttaaatta tttatctaaa agcgtaaaga ttacgattta cgctaataaa
    13801 aaataattgg aggaatttgt tgatggctaa aaaatcaaag attgccaaag caaaaaaaca
    13861 gcaagaaacg attgaacgct atgctgcttt acgccaggaa ttaaaagcgc aaaaagatta
    13921 cgaaggcttg cgtaaacttc ctttagatgc tcgtccagaa cgattgaaaa atcgtgattt
    13981 aatcgatgga cgccctcgcg gatacatgcg taaattcggg atgtcccgta taaaattccg
    14041 tgaattagca cataaaggtt tgattccagg agtaaaaaaa gccagctggt aatccaagtc
    14101 tggctgtaat gtaaaggagg agggcgcatg gaccactcct tggatcatca aaaaagatac
    14161 gttcgcttct tctagcagaa atgctggtac tagaagcaga cgtatctttt tttacgcaca
    14221 gctggtcctt ttttatatgt aaaggctgca tggttacttc gctatattta tttagtaaca
    14281 ggagtcagtg cttcgatacc cacactaatt ttcaatgctc ggtcaacttc tgccataatg
    14341 ggtcgatcca aatggcagac cttttctttc aatcttgatt tatcgatcgt tctgatctgc
    14401 tccaacagga taacggagtc tctttctatt cctgttccag tagctttgat cccaatgtga
    14461 gtcggaagct taggtttagc catttttgcc gttatggccg caacaatgat cgtcgggcta
    14521 aaatggttac ctagattatt ttgaataacc aaaactgggc gtgttccgcc ttgctccgat
    14581 cccacgactg gagaaagatc agcaaaataa atatctcctc tttttaccat aggatcctcc
    14641 ttattcttga tattctcttg gtatccgctg tcctaatccg caagccactt catagtggat
    14701 cgtacctaat tgatctgcta tatcctgcat agtgatttct ttgtctgcat ttttgccgat
    14761 aagcgtcact tttgttccga caggaaattc ttgaggcaat cggatcatca gttgatccat
    14821 acatacacgc ccaatcgttt cacagtagtt cccttctacc aatagagaaa aaccctgcat
    14881 ctttcgtggc cagccatctg cataaccgat cggtatcgtt ccgatccact ctgcttcagg
    14941 agtgatatat gtttctccat agccgattcc ttcacctgct gggagttttt tgacttgaat
    15001 caattcagaa accagctcaa gtgctggctg caatggataa acttccggta gtgcgtgccc
    15061 agagggatta agtccgtaca ttgctactcc ataacgaatc atattgccga ttgtttcatc
    15121 atgccataaa gccgttgcac tattgctgac atgtacatat cgaggaagtt cgggaagttt
    15181 tttcagcact tctataaagc gttctttttg cagattccaa tatgtatcat ctgcctgatc
    15241 tgctgtagaa aaatgggtaa ataaaccttc ccattctaat acacgacttt ctttgatgaa
    15301 tgcagctgcc tcttttactt cttcaggtgt acaaaatccg atacgaccca tcccagtgtc
    15361 tgcttttaga tgaatcgaaa gaggcgtctc tagcttactt ttctctaaaa cagcagctgc
    15421 tgcttgcaac cattcccgtg tacctgcagt tactgataaa tcatgagcaa cagctacagt
    15481 cagtgcgtcg taaggaacca tattcaagat aaggatgggc tgagtaaatc cagcttctct
    15541 caactcgact ccttcatcta aatttgaaac acaaaagccc gaagctccac ctgcaactgc
    15601 tgcctcagct gtttcaatag ctccatgacc gtatccgttc gcttttacta ctgcaaacaa
    15661 ttcttttcct tgcggaagtc ttgcaacttc atttgctaca ttttcagtta tagctttttt
    15721 atgtatcact gctttcgttg ggcggtgcca agcgacaacc atcgtttttc cttctttcta
    15781 gtcttccaaa ataatttgtg caaaagctgt ttcatttgta tgagtaatac tgacccatac
    15841 attgccttca tgaggtgaac gcgtcacaac aggctgacca ttttcatttt ttaaaatctc
    15901 gacatcttga aaggtaactt ttccgatccc agttccccaa gctttagaga aagcctcttt
    15961 gcaagcgtaa cgcccgccta aaaattctac ttggcgatga aaaggcaagg actggaatag
    16021 tttcatttca tcagaggtca agattcgtgc aatgaatttt ggtttttctt cgatcagccg
    16081 agtgatccta ggaagttcga ctgcatcgat cccaattcct tttatcatat gcttttctct
    16141 tttcaataaa tttagaacac tctcattcta ccaaattata accattttgc cacaaataag
    16201 tccacaaata acaaaaatga aagtttctct taaaaaagag aaactttcat tttatgttta
    16261 atcgttattt gaacggatta caaatccgcg ttttttatca ttgtgacgtt taccgccatc
    16321 tttttggctg ttattatttt tgctataacc gccttttgat ttgtttccac gataattacc
    16381 gccgtcacga cgattacggt tgtttccgcc accacgtttg ccatttttat tgtatccttt
    16441 tttctgcatt ggcaatgggc gttctggtgt gatcttcact ggcactgcat cagctggatc
    16501 ttttgctgtc gtttttagca aaagtgcaac taaatcttgt gcagaatatt cttctaataa
    16561 tttatctgct gtttgcaggt atttatctag accattttct gcaagttttg tttcgatttg
    16621 ttcaactgca gcacctaatt gacctttgaa tgcttctttt tcggttggtg gacgtaaagt
    16681 cgtcatccgt tttttcgtca agttttcaat cacatgcaag tagtccattt catttggtgt
    16741 aacgaaagtc acagacatac cgccttttcc ggcacggcct gtacgtccga tacggtgaac
    16801 gtagctttct ggatcttgag ggatatcata gttgtacaca tgagtgacac ctgaaatatc
    16861 taatccacgt gcagcaacgt ctgtcgctac aaggatatct aaatgaccgc tcttaaatga
    16921 acgcaatacg ctcattcgtt tttgttgaga caaatcgcca tggattcctt ctgcacggta
    16981 accgcgtgct tctaatccgc gtgccaattc gtctacacgg cgttttgtac gtccgaagac
    17041 gattgttaat tcaggtgttt gaacatcaaa caagcgagtc atgatatcga atttttcgta
    17101 ttcttttgcg cggacatagt attgatcgat caagtcagct gtcatttctt tcgctttgat
    17161 cttcacatga tgtggatttt tcatgaattt aacgccaata ttcttgatag ctggcggcat
    17221 cgttgctgag aaaagtaatg tttgtctttg atcaggaact tgtgaaatga ttttttcgat
    17281 atcttccaag aagcccatat tcaacatttc atctgcttca tccaaaacta atgtttgaac
    17341 ggttccaagt ttcaatgtgt ggcggttaat gtggtcaagc atacgtcctg gtgtacccac
    17401 aacgatatgt ggacgatctt tcaagccacg gatctgacgg ccaatatctg ctccgccgta
    17461 aacggcttgt acacgtactt ttttgtcgcg ccctaaacga tataattctt cttgtgtttg
    17521 gatagctaat tcacgtgttg gtgcgataac taaaccttgt aattcgtgac gatctggatc
    17581 gattttttct aacattggta atccaaatgc agctgttttc cctgtacctg tctgtgcttg
    17641 tccaataacg tcttttccag ctaatgctag tggaatcgtt tctgcttgga taggcgttgc
    17701 ttcttcaaaa ccagcgcgtt cgactgattt caacaattct ggtgataatt ctagttcttt
    17761 aaatttcaaa tgaatcctcc tatatggttg ttaactgagg atgtagcttt tttgctaccc
    17821 cgtcgatttg ttcggtcaaa gtgtattgtt tctttttgac agtggccacg cacgttttta
    17881 tccattctta gcccctgtgg caccaccgaa aaatcacttt gcgaagttta ggcattagaa
    17941 aagccaaacg ggtcgcgttc agctttatca ttattatgac atctggcttc aacaagttgt
    18001 ttctatggca aaaccagtcc aatttctctt catctttcgg caataggtta ttctaacata
    18061 gtttttcgtt ttctgcaagt ttacagattt ttatttcatt tgctgaagtt gttctaccac
    18121 ttcaaataag cccatgctgt tgctgccttt tagcataata ctatctgttg cttcaagatt
    18181 ttgtttgata gcatcaatca atttattctt ttctttttcc aaatagaaca caggtagttg
    18241 ggggtatttt tggttcaatt cttcttttag tgcatgcatt tgttccccat aaaggaaaat
    18301 catggcgaat ttctcaggat cgatatgttc actcatttgc gcatgcatat ttaaagactc
    18361 tttccctaat tccagcatat ctgctaacac agcgattctg cgtccttttg ttggcagatt
    18421 tttaaaagta tctaatacca gtcccatggc tgttggattt gcattgtaga catcgctcaa
    18481 aatagctgca ccatttcctg ccgttagcca ttcggttctg ttttgagtga tagaaacatg
    18541 ggcgagccct tggcgtatct caggtatgga cagtccaaag aagcgcccga tcgtatacgc
    18601 aatcaaagca ttcgttacat tataacttcc aggcagcggg atcgtaaatg tttctccttc
    18661 tactacaaaa tcggtttgtg cttttccttt tgctgtcact tccgcatgaa catcgccatt
    18721 tccaataccg aatgttgtga ctgtttgtac taatgttgcc gttaaaggtg tcagcaacgg
    18781 ttcatctgcg ggcacaacga gtaatccgtc tgatacaagt ccgtcagtga tttccatttt
    18841 ggctttagcg attccttctc gcgacccaag attttctatg tgtgcttcac cgatcattgt
    18901 gattgctgca gcttttggtt gagccataag tgaaagttcc gtgatttcat tggcgtgatc
    18961 catgcccatt tccaaaacga tcttttctgt atcttggggc atgtgcaaaa tcgtgtaagg
    19021 aagaccaata ttattgttgt aatttccttg cgtcttatat gttttgtatt tttcagacaa
    19081 gacagacgcg gttagatctt tcgtggtggt tttaccattg cttcctgtaa ttgcaacgac
    19141 ttctgcgcct actttttcca agtaataggt tgccaattgc tgcatggctt tcaaaggatc
    19201 tgctacagga ataactggaa aattttttgg agcttgttca acaggcaagc tccaaaatga
    19261 agcagatgct ccgtttgtga tcgcttgctg gataaattca tgtccatctc gcgtaccagc
    19321 aagaggaacg aataaacttc cttcggttat cttccggctg tcaaattcga cattggtaat
    19381 ctttgtcagt gcagagcatt cgctgcccac ggcttgtgca atttcttgta ttgttagatt
    19441 cattgagatc tctcctaaaa aaggttgtga aaaaagcgtt tggcctaaac ggcgggttcg
    19501 catgactctc acttccaagt aaatttctct attcgtattt agaagctaga atgaacgcgg
    19561 ttacgcaatc actccagcct cttctttatt tctctttatt catttttttc aaaaaaagat
    19621 tgacgctgat ggtatcgatt cattcctaac tggatcagtt cttcaatcaa atcaccgtat
    19681 ttcaagccca tattttccca taagagtggg tacatactga actccgtaaa tcctggcata
    19741 gagtttaatt cattcaggaa taattcattt ttatttgtca aaaagaaatc gcaccggctc
    19801 aatccgcttc cacctaacat cgtgtaagct aacttcgcgt actcttgcgc tttttgataa
    19861 acttcttctg gcacttcggc tggaatctgc atttcgattt tattattgat atattttgct
    19921 tcataatcat agaatgctac gtcttttacg acttcaccag gcaaagtcgt ccgaacgtct
    19981 tcatttccta atacagcaac ttcgatttcg cgcgcttcaa ttccttgttc aacgattgct
    20041 cgagaatcat actgataggc tgttgctaaa gcattttgca gctcttctcg gttttctgct
    20101 tttgtaatgc cgacactaga acccatattc gccggtttga caaacatcgg ataaagcaaa
    20161 gaaccttcac attgatcaaa tactttttta ggattttctt tccattgatt cttaagtact
    20221 ggtacataag gaacttgcgg cacaccagca gcttgtaaaa tatacttggt catgatttta
    20281 tccatggcac atgcactggt caatacgcct gcgccgacat aaggcatatt caatgtctct
    20341 aagaagcctt ggatcgttcc atcttccccg tttggcccat gtaaaactgg aaaaacgatg
    20401 gctccttctt ctttgatttc gcccggattg atcacttttc ctgtaaagcc ttcctctgtc
    20461 tgtccacttg ggtcccatga aagatgcaag acatctttgc tggcaggttt ttctgttagt
    20521 aatggacctt tgacccattg tccttctttt gtaataaata cgagttgaac ttggtaataa
    20581 ttataataaa tggcatttaa aactgaaaat gcggaaagaa tggacacttc atgctctgcg
    20641 ctgcgtccgc catatagtaa agtaatcttc aaaagattgt cctcctgtat tctaaatcgt
    20701 tcagtgattt actctcatat tttagcacaa aacaaaaata aacgaataac ttatttataa
    20761 aaaaacgagc cagcttctaa aagaacgagc gtcatttatt ttttgtcagc tagattattt
    20821 gtcccgtttt ttataaaaag ttatgataaa gaaaaggagg gatgatgatg gcgcaaacaa
    20881 atccacgcag ccgcttggca gaaatcattc gagtgttcat caattacaat gtagtgccaa
    20941 actttgtaca gcaaaaaaat cccgaacagg taaaaaaagc ctttgaagaa ctaggcccca
    21001 ccttcatcaa gataggacag atgctttctg ttcgagaaga tttgctttct tctgccttca
    21061 ctcaaacatt caaaacatta caagatagtg tacctagcga cacattttca acggtcaaaa
    21121 agacgatcga aacagaactt tctctttcat tatcagatat attcgatgat ttttcaaaat
    21181 cgccttttgc ctctgcttct atggggcagg ctcatcgtgc caagctgaag aacggtgacg
    21241 cggtagtcgt taagatccaa caccctaaca tcgccgaaga gatccgactt gatcttcaac
    21301 tatttgaacg agcgatccct ttgatcaaat acattcctga aactagcgta gttgatctaa
    21361 aaggggtact ccaagaagta aaacgttcct tgatcaatga aatggacttc ttaaaagaaa
    21421 gtcaaaatgg cgaacaattc tatcaaaaga acaatggctg gaaagagatc cgcagcccca
    21481 agatttatga cgctttttgt tcgaaaaaag tgatcgtgat ggaagaaatg tctggtaaaa
    21541 acttgaatca tttaatgaac gccgaaaaca aaactgaaac ttttatcact ggaattcaaa
    21601 acaagcagct gaaacaagaa gttgcaaagc ttttagttga gaactttatg aaacaggtgt
    21661 ttgatgatgg ttttttccat gctgatcctc atccagggaa tctgctattc catgtactaa
    21721 caaaagaaga acagacacaa gctagccgaa aaactgaaac agtccatgaa aaagagttcg
    21781 gttcctttgc ttttcgagcc tccacttctg cagaagaccc tgttgcgcca tataccatca
    21841 actacatcga ttttggtatg atggggcatc tttctgcagg acttaggcaa aaactcacac
    21901 aagccgtttt agcgctgtat acgaaagatg cttatcgaat cgaaaaagcg gtccttcgac
    21961 tttgtcagca agaaggctcg tttgatgaaa gtcggttcca ccaagaactg acaagttttc
    22021 ttgaacagta ttatgattct cctattgatg aaatcaactt gcaagaagta ttcacacatg
    22081 tcgtgacgat ttgtcatcaa aataatctgc agttcgatcg tgatatcacg cttttgctga
    22141 aagcatttgg gacattagaa ggggtgatcc gcgtcctcga tcctgaagtt tccctcatgg
    22201 aagtcgcttc gccttttgct caacattatt ttctcactca tctggatgta gaagatacat
    22261 tgaaacaaag cggattagac ttattggaag ggatgaaggc tgcgcctaag atccctcaac
    22321 agctccacca tctattagaa atgtggactt cgggacaagg aaaagtcaat ttggaattga
    22381 aaaagcaaga caaattattg agcaggatcg aaagtatgat caatcggctt gttttcggta
    22441 tgattttagc tgcattgatc gtagggtcct ccctgcttgt ccaagcagca cctgtagaaa
    22501 acgcagaggt cgtttcctta ttagggatat ttacgtatgc tattgccgca ttcgtcatta
    22561 tttttttggc aatcgatgca ttgatccaaa tgtataagaa gaggaaaaag tagaaaaagg
    22621 ttgtgacaga aagaatcagc ttcaagaaat aagaaggggt tttacataaa ttgtttctca
    22681 aatttttgtg aaaattcggc ttatttttcg aagaggctac ttctgaaaca ccgagaataa
    22741 aaaatgtgaa aaagctgttc tgcacccagt aataagaaca atcaaaaagg gaacatggaa
    22801 cacatttatc ctgtttccct gttccctttt tgatgtattc gagcataaat aaaatacctt
    22861 cgttacctac tatcttctgt acttggtaaa ccttagtcaa ttgccttttt taacgcttga
    22921 cgaaaagaca tatgatcttt ctccgtaaag ggttttggac cctttgtcct tatgccagct
    22981 tttcttaact ttccactatg ataacgttgt tctagaagcg tgccgatatt cgcttcgtca
    23041 aattcttttc cagagtgatg gaacactcgc acacccttcg gcaatacaag tgaagctaaa
    23101 ccataatctt gcgtgatcaa aaagtcattc ttcttaacca taccgacgat tttataatcc
    23161 gcactatcag ctccgcggtc tacgtagacg atttggacat gattagcgta ttctttggtc
    23221 gtataatggt ccacactggt cacgataacc acgtcaagac cataggattc tcctaatttt
    23281 atgacatctt cttttactgg agaaccatct ccatcaatga atagcctcat tctttttcgc
    23341 cttcttccat aaatgataaa cagttactaa tccgctcagt aaaagaccaa cattgatcca
    23401 ttttgccaag ataagcagtt gtacactttc tatcggcact gattcatggt tcagcgtgat
    23461 caataataga tggattggct ctcccatttc ttttgctaaa acaaacaaaa gcgtcatcaa
    23521 taaaaactgg tggatcacac tccctttatt ttgagtagta tacttgacaa cgatccggcg
    23581 atccattgga atagctgtat cagtttgata atattcctta tttagccagc tgcctgttac
    23641 tacgtgccag aaactaagca gaaagacacc tatcgcaaaa ccatttggaa tcaagaggac
    23701 caataaagaa gaactcagtc caagcaattg catagccaat ggagaccatg ttaaacgttt
    23761 caaaatccat ggtccgacta tttttgctgc aatcaagcct gctgcataag gcaaatacat
    23821 aaaaatcgaa agtttttcta atccgtacag tatgccaaca taaaaactgc taaataaaaa
    23881 aaggaaattc cctagcattc catttagaaa agtaaacaga tttagccagc ttggcaactt
    23941 ccattccttc ttctggtgtc ctaaaacaaa cacgaacaag atgaacagca gcaagaaacc
    24001 ataaatagca agatcaaaaa gcctttcatc gaataacaat cgggcatttc tcaaaagaaa
    24061 caataagcca aagaatatca aaaataaaac aagctctcgc gtagctacca gatttctttt
    24121 gatgtctttg aaatccagtt cgtaacgcgg ataatgacta accgtatggt aggccatgac
    24181 gtaaaaaagt gtataaatag taaagcttgc tgcaatctga gtcggtgcag gcaactcaat
    24241 cgcttgatac aggagaaata gccagatagc tgcaaataag tactttttcc catccatatt
    24301 gataaaacct tgcgtctttt cgtgaaaatt gaccgtggta ttagcaggta caagccatgc
    24361 tgcactcagc cctagcaaaa cacttgaaaa ataaaataaa ggaaaataaa atacgcctaa
    24421 tattccaagc aatgaaccag caccaccaat cagcagagcg atcatcagca acgtgtaact
    24481 atctagacca aatcgtagac tgttgactaa aaatagtcca gtcatccgaa aggcataaaa
    24541 cagcgtaaat ggcaaaatcg tcagccaatt atgcgagtct gttagtccca aaaataaaag
    24601 ataaggaata aaaataaccg tgttacttaa gataaagggc gttgtttgtg taaaattacg
    24661 cccaaatcgt ttgagttttt cgaacatgac aatggctcct taaacagtct tataactaat
    24721 ctgctcttcg attttagcat taaaggggaa ataaaccaat tttacagaat atattcttgt
    24781 aaaaaaaaat acagaaagaa gcataagctt ctttctgcat ttttacggta cttgattact
    24841 caagcagaca agcccttctc cacaaaagtc ttgcccgaca cccctgcatc cggcaggtga
    24901 taaagataga aatcaattat cctgtgcctc caaaatcaat taggagctct gtaaaccaga
    24961 gtccttctcg acccgtcgca taaatttact ttaacacagt tcctatgttt atgcgagagc
    25021 ttttttcatt ttataatcga ccatttgaaa tccttgaccg atatctgaaa taagttcttc
    25081 tgtaatctca aatccttcat gcttataaac ctcgattgct tgatgattcc cctgattcac
    25141 tcgcaaaaag atctctcttt cctttgtttg cgcagcaagt tcttcatacc agcgaaaaac
    25201 tgaagaagtc aatccttgac cacgtacttt atttagcaaa tataatttac ttaaataaat
    25261 ttttccattt atctcttcat aagcagtgta accgacagtc ttttcttcgc tttttaataa
    25321 aaagtaggac acaccttctg tcagttcttt ttgaatctgt ttttttgact gataagtttt
    25381 cagcatgtaa tccacttgtt tttgaccaat gatcggcaca aaagcttccg gccatacttc
    25441 ttgtatgact gccatcagct catccagttc attttctgtt acttttattt tttccataca
    25501 cccacgtcct tttttacatt ataaatgacc ttgcgcttga tggaataaaa agagcatgat
    25561 catgctatac acacccaccg accatggttt caagaaaatc acaatctgca taaattccct
    25621 aaaagataat ttcgtcaaac cagctactag acagatcaag tcgtctggcg caaagggaag
    25681 cagcaaggta acaactagta cttttttaat atctttcgtt tttcttgtca gcaattcatc
    25741 aaatttctga tacttttttg gcgataaaat aagctggaca aaggctacgc catagtaacg
    25801 gacaagcaaa aatccgattg cttccccaat cactaggcca atacaactat ataaaagccc
    25861 aaatccattg ccaaacatca gcatgcccgc tactgaggag atccctcccg gcaaaatagg
    25921 aatgatcact tggatcactt gcaacagaac aaatatcatc actgcatact tgccaaattg
    25981 ctggataaac gcttgcaaag acgtgctcga tcgaaaaatc ccatgatgat aagcataaag
    26041 aatcaacaca aagaaaaaaa acagaccaat aatgggcatg atctgaagac atttttgtaa
    26101 aactgatcct tttttagaca tctatattcc ccacatcttt tttcatttat taaaactgcc
    26161 tcct
//
LOCUS       DBBGRF010000041        25502 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000041 DBBGRF010000000
VERSION     DBBGRF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.041"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            133..3660
                     /locus_tag="ACIZD4_001940"
     CDS             133..3660
                     /locus_tag="ACIZD4_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HGC5990851.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="ACIZD4_001941"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="ACIZD4_001941"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGC5990852.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="ACIZD4_001942"
     CDS             7448..7789
                     /locus_tag="ACIZD4_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HGC5990853.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="ACIZD4_001943"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="ACIZD4_001943"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGC5990854.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /gene="pheT"
                     /locus_tag="ACIZD4_001944"
     CDS             9146..11566
                     /gene="pheT"
                     /locus_tag="ACIZD4_001944"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGC5990855.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACIZD4_001945"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACIZD4_001945"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGC5990856.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="ACIZD4_001946"
     CDS             13000..13737
                     /locus_tag="ACIZD4_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC5990857.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="ACIZD4_001947"
     CDS             13751..14566
                     /locus_tag="ACIZD4_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGC5990858.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="ACIZD4_001948"
     CDS             14579..15226
                     /locus_tag="ACIZD4_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC5990859.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="ACIZD4_001949"
     CDS             15242..15898
                     /locus_tag="ACIZD4_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGC5990860.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="ACIZD4_001950"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="ACIZD4_001950"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGC5990861.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="ACIZD4_001951"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="ACIZD4_001951"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HGC5990862.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="ACIZD4_001952"
     CDS             18240..18758
                     /locus_tag="ACIZD4_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC5990863.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /gene="cbpB"
                     /locus_tag="ACIZD4_001953"
     CDS             18865..19365
                     /gene="cbpB"
                     /locus_tag="ACIZD4_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGC5990864.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="ACIZD4_001954"
     CDS             complement(19645..20565)
                     /locus_tag="ACIZD4_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HGC5990865.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20691..21743
                     /locus_tag="ACIZD4_001955"
     CDS             20691..21743
                     /locus_tag="ACIZD4_001955"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGC5990866.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="ACIZD4_001956"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="ACIZD4_001956"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HGC5990867.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="ACIZD4_001957"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="ACIZD4_001957"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGC5990868.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="ACIZD4_001958"
     CDS             complement(23383..24144)
                     /locus_tag="ACIZD4_001958"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC5990869.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="ACIZD4_001959"
     CDS             24333..25427
                     /locus_tag="ACIZD4_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HGC5990870.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4424 c         5384 g         7247 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg tgcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 gg
//
LOCUS       DBBGRF010000042        24333 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000042 DBBGRF010000000
VERSION     DBBGRF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.042"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(132..2477)
                     /locus_tag="ACIZD4_001960"
     CDS             complement(132..2477)
                     /locus_tag="ACIZD4_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HGC5990871.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKNEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            2756..3658
                     /locus_tag="ACIZD4_001961"
     CDS             2756..3658
                     /locus_tag="ACIZD4_001961"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HGC5990872.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            3869..5644
                     /locus_tag="ACIZD4_001962"
     CDS             3869..5644
                     /locus_tag="ACIZD4_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HGC5990873.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(5710..7296)
                     /locus_tag="ACIZD4_001963"
     CDS             complement(5710..7296)
                     /locus_tag="ACIZD4_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HGC5990874.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            7547..7771
                     /locus_tag="ACIZD4_001964"
     CDS             7547..7771
                     /locus_tag="ACIZD4_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGC5990875.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            7913..9664
                     /locus_tag="ACIZD4_001965"
     CDS             7913..9664
                     /locus_tag="ACIZD4_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HGC5990876.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLERELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            9664..11448
                     /locus_tag="ACIZD4_001966"
     CDS             9664..11448
                     /locus_tag="ACIZD4_001966"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5990877.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQEFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            11783..12635
                     /gene="licT"
                     /locus_tag="ACIZD4_001967"
                     /pseudo
     CDS             11783..12635
                     /gene="licT"
                     /locus_tag="ACIZD4_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
     gene            12732..14618
                     /locus_tag="ACIZD4_001968"
     CDS             12732..14618
                     /locus_tag="ACIZD4_001968"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC5990878.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAADGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMSLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVINYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(14659..15561)
                     /locus_tag="ACIZD4_001969"
     CDS             complement(14659..15561)
                     /locus_tag="ACIZD4_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC5990879.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            15791..17194
                     /locus_tag="ACIZD4_001970"
     CDS             15791..17194
                     /locus_tag="ACIZD4_001970"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGC5990880.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            17194..18627
                     /locus_tag="ACIZD4_001971"
     CDS             17194..18627
                     /locus_tag="ACIZD4_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGC5990881.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            18772..19698
                     /gene="trxB"
                     /locus_tag="ACIZD4_001972"
     CDS             18772..19698
                     /gene="trxB"
                     /locus_tag="ACIZD4_001972"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGC5990882.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            19911..21638
                     /locus_tag="ACIZD4_001973"
     CDS             19911..21638
                     /locus_tag="ACIZD4_001973"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGC5990883.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            21654..22004
                     /locus_tag="ACIZD4_001974"
     CDS             21654..22004
                     /locus_tag="ACIZD4_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGC5990884.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(22098..22958)
                     /locus_tag="ACIZD4_001975"
     CDS             complement(22098..22958)
                     /locus_tag="ACIZD4_001975"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HGC5990885.1"
                     /translation="MSSDSTEIITFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            23050..23478
                     /locus_tag="ACIZD4_001976"
     CDS             23050..23478
                     /locus_tag="ACIZD4_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HGC5990886.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            23640..23816
                     /gene="rpsU"
                     /locus_tag="ACIZD4_001977"
     CDS             23640..23816
                     /gene="rpsU"
                     /locus_tag="ACIZD4_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGC5990887.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            23843..24289
                     /locus_tag="ACIZD4_001978"
     CDS             23843..24289
                     /locus_tag="ACIZD4_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HGC5990888.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         7707 a         4352 c         5186 g         7088 t
ORIGIN      
        1 gtttttcaca tttttacata aatttgtctt aatatcgtag atgtaagctt ttgaacacca
       61 tttattcgga aaaagggagc tgtgacaaga tttttgtcgc agctcccttt aattctgatt
      121 aatctattag atcaatcatc tttatcgtct gattctttgg tctctggatt cgctctagca
      181 taagctgaag cggtgttcca gtaatctgta tagttttcat cagtaccgcc tacgccgaat
      241 ttaaaggcgc ttttcttcgg accatttttt gcccaaagtg actccactgt ttttcctggc
      301 gtttggatgg attttttatt gacagtaact tttccagctg tttgtcctgt gaacccagat
      361 acttttttct tcatcacatc ggatgataag tcaaatttct catcagtgcc gaaaatctca
      421 gggtttgctt ggtaagcttg attgattaga ttggcaagat aattagccga acgtattctt
      481 gcttggctgt ccattccagt attgtcatcg tgtcctgccc aactactgat agtgatagat
      541 ggagttgaga cgatcagcca tgaatctcgg tattcattgg tagaaccagt ttttccgacc
      601 caatctgcat ttcctagatt tccgtttaag cttgagatga catctttgaa tggtgtagtg
      661 attttttcat tgatcacact acgcatcatg tcattcatga tcgatgccgt tgcttcggaa
      721 taaatacgga cagaattact ttcatgttta taaatcacat tacctgcatt atctgtgatg
      781 gaatcaatga tatagccttc ttcgtagact ccaccatttg ctaaggcctg gaatccattt
      841 gtctgttgaa gcgtcgttac atctactgtc cctaaaggag ccgattcaac gccccaatta
      901 tcatttgctg ggtagttcat cttcgccaag tagtgctcgt aagcgtattg tttcgatcca
      961 ccggaattca acacatcttg atataagtga taagctggga tattgttgga ccattccagt
     1021 gactcacgga cggtttggaa ggtgttcgac ccttcattgg tcgcattgac gattttctca
     1081 ccagcatttt ttccttcttg ccaagtcgtt gcataatctg atacacggga ttctgatccg
     1141 acaagtccca tatcgattgc aggaccgtaa acaagaaccg gtttgatgga tgaaccagct
     1201 tgacgttctg tatcaaaggc gtggttattt tgattctggc tgtaattccg accacccacg
     1261 aagccataga tacgtccggt tctgttatcc atcaatacat ttccagtctc cacttggcta
     1321 ccagcaccat catctaacat gtagccataa ttttctacgc cggtttgtaa tgcagcatag
     1381 atatctttat cgatcgtcga atggatcgta tatcctttgt tttggatcgt ttgctgtgct
     1441 ttttgataat aagcttcact gaccgatgaa tctgacatat cagcattatc tttttctgcc
     1501 aattgttgtg caataatcct tgttgcttcg ttcatcacgg tataatacaa gaattctctg
     1561 tcagtctgtt ccgcgatttg ttgtgggaga aagtcttttg taagatcata ggctttcgct
     1621 tcttcgtatt gttctttcgt aatttgtcct tcacggtaca tactgaataa aacaaaatct
     1681 tttctggcaa gaccggcaga aagatcttct tttagcgcgc ctgtattcgt gtatggacta
     1741 tacgtgatag ggctttgagg caaaccagcg atataagcag cttgtggcag agtcacatcc
     1801 tttgcatcta caccaaagat tcctctagca gcttcctgga ctccagcaat attttgcccc
     1861 ttattattcc gaccaaatgg tgagacattc aaatacgtag taatgatctc attttttgaa
     1921 aagtgttttt ctacttgtgc agaaagaacg atctcgtttg ctttacgttt gaatgttgtt
     1981 tcatcggtta ggatctgttg tttgactaat tgctgtgtca aagtggatcc tccagacgag
     2041 ccgatgccag tcgcttctga aactagtgct cgtaaaacag ctttagggac ataaccttga
     2101 tgtttatcga agtattcatc ttctgtactg ataatcgcgg ttttcaataa aggcgaaatc
     2161 ttatcagatg aaatagtcgt ccgcatcaga tctgtctgga tttttgatat ctctgtatta
     2221 tctgcataaa caatctttga cgtttccgta atgtttccta gttctgtctg cagttctttt
     2281 ttagtcggca attgtgtgtc ttcgacaaga taggcaaagt agccagcacc tattccgata
     2341 cctagagctg cgaacaacaa aagaagaaca gtaataaaaa cagtcaatga ttgaaacact
     2401 ctaaaaataa tcttaggaac aaaccatttt tctttttttc ttctattctg tttttttcga
     2461 gtatttttgc gtggcaaaag ggtcacctca actaatggtt ttatttcgct aattatagca
     2521 aataatagga caaaaaaaca gacaaggctg tttttgacag gaatttcttt ttcgaatgag
     2581 ataaaacgtg aggaaatgat cttttttatg aaagagttct taagcttttc tttagggaaa
     2641 gtttcagtta ctatggagaa cagggcaaag aaaaacaaac cattttcttt gtacatcatc
     2701 ttatcaatat acaggaattg ttcgaaacaa ttgcctttca aggaggaatc catccatgtt
     2761 attaggctca catgtcagca tgagcggaaa gaaaatgctg ttaggcgcgg cagaagaagc
     2821 agccagttac ggatcttcga cctttatgat ctatacaggc gctcctcaaa atactagaag
     2881 aaaagctatc gaagagatga atattgatgc cggaaaagca tttatggcag aaaacggact
     2941 aacaaatatc gtcgttcatg cgccttatat cattaatttg ggaaatacga tcaaaccaga
     3001 aatgtttcca tttgctgtac aatttctgag agaagagatt gtccgtgcgg aagctttagg
     3061 tgctactcaa atcacccttc acccaggcgc tcatgtagga gcaggggcag aagctgggat
     3121 tgctagaatt attgaggggt tgaatgaagt tttgacaaaa gaacagacgg cacagatcgc
     3181 tttggagacg atggcaggga aaggtacgga aatcggtcga acatttgagg aattagcgca
     3241 aatcatcgat ggagtaaaat tgaatgaaaa attatccgtt acttttgata catgtcatac
     3301 gaatgatgcc ggatataata taaaagaaga tttttcaggt gtaatggaag agtttgataa
     3361 ggtcatcgga ttagatcggc ttaaagtact gcatatcaat gattctaaaa atccacaagg
     3421 ttctcataaa gatcggcatg ccaatatcgg ttttggaaca attggatttg acacattgaa
     3481 caaaatcgtc catgatccaa tgtttgacaa catttcgaaa atattagaaa ccccatatgt
     3541 cggtaaagat aaaaagaaag cttacgcacc atatggaaaa gaaatttcca tgttcaaagc
     3601 gcaagcattc gatcccgaag tgttccctga gttattagca gaagaagtca cactttaagt
     3661 tttctacctg acagcaacaa aaaaggattg ggcagtctgc cttgtccttt tttgtttaag
     3721 aaacaaagga gtgctttttg cattcgtttt cgccatgctc cttttgcccc ctctttttaa
     3781 attcagacaa acagggtata ctgatagaaa agtaaaaaac gaaaagtttc acaaacaagt
     3841 agcaaaacgt gattgaaagg acgaaaagat gctgaacatt ttaaacccct tgatcgacca
     3901 actaaaaaag aaacatacat actttattct tggcatagcc gtattattta caattattcg
     3961 gttgtattta tatagtaaag caatctatgg aacagatatg tcggcgacct atgatgatca
     4021 gctgctgatt cactatgctc aaaatatttt ggatggtaaa tggctagggg agtatacgac
     4081 tacaacactt tccaaaggaa tctcctacag cttattttta gtacttgcac ataaactgca
     4141 tctttcttat gcagttttgt tcggcatgtt cagtattttt gccagtatat tggttgcact
     4201 cgcgtttaaa ccgattgtga agaacaagta tcttctttta agtatctatt tttatttttt
     4261 gttttctccg attagtttta cacatgaata ttccactcga acatatcgta atgccctcgt
     4321 gattccggct gttgagatca ttatcgcttg tttattagct atttattacc gcaaatacgg
     4381 ttctagcaga aaattgctgc catggttttt agggctttct gtcgcttttc ctttcttttg
     4441 gttcattcgc gaagattcta tctggcttct tccttttact gtagtagctt tgggtatcag
     4501 tttcgtccag atcttgctag ggcaagactt ttctttcaaa gaagtaaaga agttaaaaaa
     4561 acgactcttt cttctctcga aacgggaatg gctgaaactt tcattgtttt tacttcctat
     4621 agttggcttt tccatcgtct atcagtggat cgaatataaa aatgagacaa catacggtat
     4681 tgcaaccatc aatgaccgtt ccagtggaga atttggacgt ttgatgaaac aactgatccg
     4741 aatagatgat gaaacgaact tgaataaaga aaacagtgag atatgggtct cacatgctgc
     4801 actaaataaa gcattagccg catctcctac attccatact gtttctaccc gtattgacga
     4861 attatatacg actcacgcgt ggactcaagg tggaaaagta aaagaattac ccggagatat
     4921 catcttttgg gcattgcgag atgtggtaag cgaatctggt tattaccaaa acaatgcaaa
     4981 agaaaccaat gatttttgga aaaaagtcaa ccaagaatta gaagaagcct atcacaaggg
     5041 aaccatcaaa aagaaaaaag agttctatct gatgggatca ggagatggaa agacgatgag
     5101 tgatctgcca atcgtattcg atttccttca atcaggatac gcttatgcat ggcgatataa
     5161 agatttccat caaggaggaa attatagttt cggaacgcaa gaacaagtca aacaggctca
     5221 agaattatta aaccttccgc taatggagaa ttggatcgat agtaatgaac cgagaacacc
     5281 taatttccaa ttaacaaaat cagcaaaagt cgcgaatgtc atcataaaaa tttaccaagt
     5341 tctggctatt cccgtgctga ttgcttcaat agcagggata ttacttatga tactaggaac
     5401 cgtatttgca aaagctgatc gtgcctatta tagttcctct ttgattgtgg tcaccggatt
     5461 aatactgaca caattggttt ttcttttcgg tgtctcatgg ttttgttctt atgcgccaga
     5521 aaaaaaggac tattttttaa gtgtctacac tggtgcaggc gtgccattaa cgcaattcat
     5581 cgtagtaaca agcatgctag ttttcagtaa attaaatctg aaaaaagctt tatcttctaa
     5641 ataaaaagac ccttggtagc tagattttta acctaactat caagggtctt tgtgtggaaa
     5701 aatcagtttt tattcgattt cttctaccgt ttcctgcaaa agctgttcat attttttgtt
     5761 tcctttatat aaatcaccaa tcgtccatgc caacaggaga aggacaagaa caatgattac
     5821 ataagcgatg tgatcagcca atgctagttg agcggaagtg gcttgctcgc cgaagaaact
     5881 ttcgatctgt cctggtaatc ctcgtaagtt caagtaagtt agactaatca cagagaacca
     5941 gccaagaagt tttacgatga atgaattttt aaatcggcta cccatctccg cttggctgtt
     6001 ggtcatcatc agtaaaggaa tcatcgaaaa tggcaacgca aaagccaaga acacctggga
     6061 ttcattcatt aagttattca aagcggcatg ttcttcgatc gttccttttg tacttgtaaa
     6121 caaaacacaa atcaatacag gaatcacaga aagcaatcgt gtgaccagtc ttcttagcca
     6181 aatcgggata cgcatatgga tgaatccttc catgatgact tgaccggtca acgtaccagt
     6241 aatagtagag ttctggccag aagcaagaag tgctacagca aataaagtgg acaagatacc
     6301 agattttgct acagcaatca aaataccatt gctcatagct gatggatcag ataaagcttc
     6361 atacagacca aaaaaggaag gatcttggac agaaccggtt ttgaagacag cgacacccat
     6421 gatcaatagc agtgcattga ctagaaaagc cattgacaac tggatattag aatcccaagt
     6481 agaaaaacgt acagcttgtg ctacatcttc ttcgttttgg tgatcgatct tccgagtttg
     6541 tgaaactgct gaatgaagat ataagttatg cggcatgact gttgcaccaa taatccctaa
     6601 agctccagtc agcggagttt cgccgccgat gaccggtgag tctgagaatg tatgactgtt
     6661 agggataaag ccagcaaata aactgtgcca atctgggtta gacaagccaa cttgatagac
     6721 aaaaacgaat aaaatgacga aaattaagca gacaaccagt gcttcgatct tacgaaaccc
     6781 gacttttgtc agtagtaaga gaacgaaaac atctaataca gtaataaaga cggcaatcac
     6841 caatggaata tcaaaaagta agtagagggc gattgctgca ccaatgactt ctgcgatgtc
     6901 tgttgccata atggctaatt cagtcaagat ccataaaatg acacccaatg tcttacttgt
     6961 ccgtgctcgg attgcttggg ccaaatccat ttgggtcacg attcctaatt ttgctgccat
     7021 atactgtaaa agcatagcaa ttagactaga catcaaaata actgacatca ataaatattg
     7081 gaaattttgt ccaccagtga tcgaagtgga ccagttacct ggatccatat aaccaactgc
     7141 tactaatgca cctggtccag agtaagcaag aagtgtttta aaaaaacttt ttccctttgg
     7201 tacatccact gttccattta cttcagctaa agataaacca tttgtatgtt caataagtcg
     7261 atgcttatga aattgtttgt tggattgatt attcaagaaa aaaccacctt tcctatttat
     7321 ctacgattac attctacacc tcagaaagaa aaaattaaag aaaaagattc ggtatgccta
     7381 attttttttc gtggtgtgtc ttgctggtta atgaaagaaa ttttgttctt ctctaaaaaa
     7441 accactattt tttgcatgaa actaaagaat acgcctttct tttttcaata aactttagta
     7501 aaataaatca ttgagagcaa ttcggaaata gaaaggagag atttatatgg tatcaacagg
     7561 tattgtcgta cttattgcta ttattgcttt gctaatcggc gcagtaggtg gctttttcct
     7621 agcgcgtaaa tatatgaaag actatttaga aaaaaatcct cccgttaatg aggacatgtt
     7681 gcgatcaatg atgatgtcaa tggggcaaaa accatctgag aagaaaattc gccagatgat
     7741 gcagcaaatg aagaaccaag ggaaaaaata ggttctgacc caaagacttt ttgcgggctg
     7801 attttttcag tccgtttttt atttcgtaat ttgttagact attcagacta ttcagcaaaa
     7861 aagacaagca cagacaatcc tatgctcttg ataaagacaa aggaggagta aaatgtcgat
     7921 ttttagaaaa ttaggttggt tttttcgtca ggaaaagaaa cattatttaa ttgggatttt
     7981 ctccctattc gcagtggcct tggtacagtt agttcctcca aaagtgattg ggatcatcat
     8041 tgatgagatc gccgataaga atttatcaat aaagatcatt tcctggtgga tcttattatt
     8101 gatccttgca gctttcttac aatatctttt tcgttatatc tggcggacga atatttgggg
     8161 aagtgcagct cggttggaga gagaacttcg gcagcagcta ttcaaacatt ttacagaaat
     8221 ggacaatctc ttttaccaaa aatatcggac tggagatttg atggctcatg caacgaatga
     8281 tttgaatgca atccagaatg tagcaggagc tggaatcttg acctttgcag attcagtgat
     8341 tacgggcgga acaacgatca ttgcgatgat tttgtttatt gattggcgct taacactgat
     8401 tgcgctgatt cctctgcctt tgctagccgt tacttcacga gtgctggggt caaaactcca
     8461 cgatgctttt cgtgattcgc aagaagcttt ttctagtatc aatgataaga cacaagaaag
     8521 tatcactggg atcaaagtca ttaaaacatt tggacaagaa aaagaagatc tcgcggattt
     8581 tgaagaaaag attgaagatg caattattaa aaacaaacga gtcaattttt tagactcctt
     8641 atttgatcca ttcattacct tgattatcgg tctgtcttat gttgcaacaa ttattttagg
     8701 tggaaagtat gtcttggaag gcacgatctc aatcgggcag atggtctcat ttattagcta
     8761 tatcggtatg cttgtttggc cgatgtttgc gattggtcga ttgttcaacg tattggaaag
     8821 aggaaatgct tcttatgatc gcgtcaatga acttttgcat gaaaagacgc atatcgtgga
     8881 acaactgggt gcagtgcaga ccccggcaaa aggcgagctg aatgtagcta tttcctcttt
     8941 taactatccg aaagaagaat caccagcatt agaacaaatc aaatttgcga tccaagaagg
     9001 agaaacatta ggtattgttg ggaaaactgg tgcgggaaaa acgacaatca tcaaattact
     9061 gatgcgtgaa tacgatgatt atcaagggaa aatccaattt ggcggacgtt cgatcaaaga
     9121 atattcattg aatgctttat taggatcaat cggttatgtg cctcaggatc acttcctgtt
     9181 ttcgatgacc attcgagata atatccgttt ttctaatcca aaactttcag aagaagaagt
     9241 agagcatgcg gcttctttag catttatcaa caatgaaatc aaggaattgc caaaaggtta
     9301 tgatacctta gttggagaac gtggagtctc tttatctggc ggacagaaac agaggatttc
     9361 gattgctcga gcattgatca aaaatcctga attgctgatc ttagatgatg cactttctgc
     9421 agtagatgcc aaaacagaag aagctatctt gcataattta aaagaaataa gaaaagagaa
     9481 aacaaccatc attgcagctc accgtttaag cagcgtgatg catgcaaaag aaatcattgt
     9541 tgtcgatcaa gggaaaatca ttgaacgagg aacccaccac gagctgcttg cattaggtgg
     9601 ctggtatgaa cgaatgtggg aaaaacagca attagaagcg aagatagaag gaggcgaggc
     9661 ctgatggatg aaaattatca atcggaatgg acaaaatcga ttccacttaa agaacagaag
     9721 aagatcatca aacgactgat gaagttcgcc aaacctttta gaagaacgtt catcgttgct
     9781 atcttatttg cgtttgccct gtctgtgatc aatgtcctat tgccaaggat catccaaact
     9841 tttatggatg atcatctggc taaacagtca gctacgacac aagttatttt gttttttgct
     9901 ggtgtgtact tgtttggagt catagtcaaa agtatcattt ggtttttcca atggtatttg
     9961 tattccatgg cttcattgaa gacctatcag tatgttcggg taagattatt tgaaaagctg
    10021 catacactag gtatgcgtta ttttgaccag acaccggcag gatcgaccgt ttctcgagtg
    10081 acgaatgaca cagaaacgct atttgaattt tggtatgtct ttttgatggt attgactggg
    10141 atctttgcag tcgtttcttc tttcgttgcc atgtttcaaa tcaatggaga aattgccttg
    10201 tggactttgg tgttcttgcc gattttagga atcgtcatct ggtattacca gaaattcagt
    10261 tctcgtattt accgaaatat gcgggaaaaa ttaagtcagc tgaacacgaa attgaatgaa
    10321 tcgatttccg gcatgcgtat tatccagcag tttcgccaag aagctcgttt agctaaagaa
    10381 tttgaacaag tgaacaacga gtatttagac acgcgctatg cgatgatcaa aacgaattcg
    10441 attctgttaa gtccaatcat caattttctc tatgcattgg cgattgcgtt ggcgttgact
    10501 ttgtttggga tcgatgcgtt gcattctccc gtagaagttg gactgatcta tgcatttacg
    10561 acctatgtcc aggaattttt taatccaatg tctcaaatga tggacttttt gagcaccttt
    10621 acagatggga tggttgccgg tagtcgtatt ttgaaaatca tggatacaga agaatatgca
    10681 ccgcaacaaa atcctggagc agatcaagcg attacttcag gtaagatcga gtttcgcaat
    10741 gtaagctttt cttatgatgg agagcacaat gtattgaaca atatctcttt tgtcgctaat
    10801 ccgggtgaga ccgttgcatt agtggggcac accggaagcg gaaaaagctc gatcatcaac
    10861 gtattgatgc ggttttacga attttatgaa ggccaaatct tgattgatga tcatgacatt
    10921 cgagaatatc caatggaaga gttacgtaag aaaatgggat tggtcttgca agatgccttc
    10981 ttgttttatg gagatattgc aggaaatatc cggatgatga atccagctat cacagacgaa
    11041 cagattcgcc atgcagctga gtttgttcaa gcaaacaagt tcatcgatga attaccaaaa
    11101 ggatatcact caaaagtgat cgaacacggt gccagctatt ctagtggaca acgacagctg
    11161 atcacttttg cgcgaacaat cgtgacagat cctaaaatac tagtattgga tgaagcaaca
    11221 gcaaatatcg atactgaaac cgaaggattg atccaagaag gattggcaaa aatgcgacaa
    11281 ggacggacaa cgatagcgat tgcccatcgg ctgtccacga ttcgggatgc agaattgatt
    11341 ttagttttag acaaaggtca tatagtagag cgtgggaatc atgaaacact tctagcgcaa
    11401 aatggtttgt atgcagatat gtacaaactg caaagcagtg gtgtgtaaaa agaggttgtg
    11461 acagtagcat agtagcattt tgccctaagc gctagagtga aaataaaaca gagcttcgca
    11521 gattcttcat ctgtgagcgt tagtggcgta gtcacccgat ttaaaaaaga cgacgacagc
    11581 tagtcaaaag cggctaataa ccactaagaa agcgttgaca aaagcgtttg ctttcgataa
    11641 tataaagaaa acgatacaac ttggatagtg attgcctgat gcaagctaaa cctgatgagt
    11701 ctcccatggt tccatggacg gctttttggg tttttctttt tgttttggat acagccctat
    11761 atatcatgga aaggagcaaa acatgctgat tgagaaagta ctgaataaca acgtcgtaat
    11821 aaccagggat gaaagaaatc aggaaatgat cgtgatggga aaaggtttgg cattcaaaaa
    11881 gaaagtgggt gacccgattt ttgactcatg catcgacaaa aaatttcagt tgacaaatga
    11941 cgggctttca caacagttcc aagaattggc acaagcgatt cctcttgagt acttagaaat
    12001 ttcttgtgaa atcattgaat atacaaaaga ggctctacaa gtccagttga atgattctgt
    12061 gtatattgca ttgacggatc atttgtatac ggctatcgaa cgtcacaaaa tgggaatatt
    12121 tgtaccaaat gtattgctgt atgatatcaa acaactattt cctaaagagt atgccatcgg
    12181 gaaaaaaaac agtgaagaaa atctcggata aataccacat caagttatca gaagatgaag
    12241 ccggatttat cgcattgcat ttagtcaatg cacaaggcat tcaaagccaa caagacaata
    12301 cctacctgtt cactataaca atacaggata ttctaaatat cgtccgctat tactataaga
    12361 ttacatttga tgaagattca gtccattttt ttcgattcgt cacacactta cgtttttttc
    12421 tgacacgcgt cctagatgga gaaaaatcag aagtgggaga agtttctgag gaattgtttc
    12481 aggttattca aaaaaaatat aaggatacgt ttggttgcgt tgagaaaata gcagactttt
    12541 tagccgagac gttcaactac cagatgtcca cggacgaaaa aatgtattta acgatccata
    12601 ctgcgcgttt agtgcatgag aatcgttgta aataaataaa aaaaggagga taaattaaca
    12661 agaacgtatg aaataagggt agtgacattc agttggctaa accttccact aataaattgg
    12721 agggaataga aatgggaaaa taccaagaat tagcgagaaa aatcgtagaa aatgtcggcg
    12781 ggaaggaaaa tatcaatggt ttgacacatt gtatcacaag gcttcgtttc aaattaaaaa
    12841 acgaagaaaa agcaaatgat gagatcttga aaaatatgga cggtattgta acggtaatgc
    12901 gagcgggagg gcagtatcaa gttgtcatcg ggaatcatgt gccagtcgtg tttgaagagg
    12961 ttataaaagc aggaaacctt acttttgatg aggctgtttc aacagaaaaa atgagaccgt
    13021 ttgatatgct tattgatgga atatcgggct gtttccaacc attccttgct atcctagctg
    13081 ctgacgggat gattcgtgga ctgacagcat tccttgtctt cttaggcgcg tttgaccgcg
    13141 gttctggcac atttgttatg tttgataata tcggtgattc tgtattccaa tttatgcctg
    13201 ttattatcgg tttaacagct gcccgtaaat ttaaagtaaa tgaattcgta gggatgttgc
    13261 ttggcgcagc attaatgaat cctagcttgt cgctggaagc tttgagtggt gcagcagaag
    13321 caccactaac gaccatattt tctggcacta tttttgaagc acctatttat caaacagtat
    13381 tcggcattcc ctggattgcg cgtaactacg cttcttctgt cattcccatt atctttattg
    13441 tgttgttagc tagccaaatt cagaaaccaa ttaaaaagtt agtacctgag atgatcgcga
    13501 atttcttcgt tccattcttc accgttctta ttacaatgcc tttaggtttt ttactcgttg
    13561 gaccagtatt cacattcgca actgatattt taatggctgg atttgaaaca cttttagcac
    13621 tttcgccagt tatttatgga gcaatcgtag gcttcttctg gcaaattctg gtgatgtttg
    13681 gtctccattg ggcaatcgta ccaatgggat tgatgcaatt ttctgtgaat ggttggcaaa
    13741 atattatgac acctgttgca gtagtgtctt ttggacaaac tgcagcactt accgcactct
    13801 actttaagct tagaaatcca aaagacaaag caattgcaat accagccatt gtttctggta
    13861 ttgtggggat tacagagcca gctatttatg ggtttacatt gccacgtaaa aaaatattta
    13921 tttttacctg tgtcggtggt gcgttagggg gcgcgtatag tgggttaatg aatttaactt
    13981 cttggaatca aggtggacta ggcatcttta caattcccaa ctatattaga ccagatggtg
    14041 atttaacaga tgtgattaat gtattgattg ggatcgccat tgcgatggtg gtatcctttg
    14101 cgctgacttt tttcttttgg aaggaggaag cagatgaaac agatgataga cagaaaagat
    14161 caggtaaaga aattgtaaaa acaccgatac aaggacaaat cgctccactg aatgcagcaa
    14221 aggatgcagc ttttgcacaa ggaacactag gtcgaggaat cttgatctac cctgaaaaag
    14281 gagaagtacg tgcccctttt gacggaacag tcatgtccct gtttccgacg aaacatgcaa
    14341 tcgggatggt ttctgaagca ggtctggaat tgctgattca tgtcggattg gatactgttc
    14401 agttggaagg gaaatatttt gaaagcttgg tgcagcaagg agaaagagtg aaacaaggcg
    14461 atctgttgct tcgcttcgac aaaaagaaaa tcgaagagga aggatacagt ttagaaacac
    14521 ctgtgattgt catcaattac atggattatt tggatatttt ggaaaatcaa ggggaaacgg
    14581 tcgggccaga cgatgcactt atcaccgcac tgacctgaac ggttaggtga aagaatggac
    14641 taggcttaac tattcttttt agtccacttc tttattttca aaattgaaag gctctttcat
    14701 gatggctgag ctgatagggc gtttatcaaa tttttgtcct acagaaatta gatggactaa
    14761 attctgttga taattttctg caaaaacaca actatataac acgtctagaa gataacaaat
    14821 cgatgtattg atcgtaaaat taccaatttt cgaatacagt cgttcgcgtg tcgtaagtcg
    14881 caaagcggct gtactcattg aagatagcgt tgaatcaccg atactggtca aagctaaaat
    14941 tggcacatga ttttgtttca atatttctgc ggtacgaagg atcacattgt tttcacccgt
    15001 ataagaaatc agaatcccac acatatcact tgtgcaattg tacgcttcat agaacgattc
    15061 accaaaagtg gtgacaatcg tgacatccat tttgatgcgc ttcattttca gcatgaaatc
    15121 ttgagaaatc aaagtattcg agttactggc gaaaatcacg attttttttg cttgaagcat
    15181 tagttgtttg gctttttgca gttggtcatg atgaatgaga gaaagtgtat cttgaatcgt
    15241 catctgttct aaagaagcca ttttatttgc gatcgtcata ataccgtctg tggtggaaaa
    15301 aggaagattc gcatctacgt cttgaaaatt cccttcaaga taggctgttt cagctaaaaa
    15361 agcattacga aaactgaccc agccatcaaa acccattttt tttgctacac ggatgagtgt
    15421 ggacgggtgg acataacatc gctcagcaat ctcttggatg gtcatttcgc caagtgctgg
    15481 agaatcgctt aagagaaact gaatcacttc attttctgaa ggagaaaagg agatttcttt
    15541 gattttttca cgtaataaca tgtagatacc ttcttcttgt ttttttacgt aaatcataac
    15601 ttttttgaaa atgatttgta aacggattta tgttatatag cttaataaag acattttttg
    15661 acaagatatt tacaaaaatc cagaagaaaa cactaacttt tgtaaatgtt actggaaaga
    15721 aacgaatttc tattgtttgt tttgtttaca aaaaagataa taaaagtgta aaaagtaaag
    15781 gagtgagaac atggcaaaag gaatcaaaat cgctacgatt ggtggaggca gcagttacac
    15841 ccccgagttg atggaaggat ttatcaaaag atatgaggaa ttaccgatac gagaaatctg
    15901 gctcgtagat gtagaagaag gaaaagaaaa gcttgagatc gtcagtcaga tgtctcagcg
    15961 tatgtgggat gcttctccgt atgaagtcaa aatctatgca actctggatc gggaagaagc
    16021 attgaaagat gcggattttg ttacgactca gtttcgtgtc ggtcaattag atgcacgaat
    16081 caaagacgag cggatcccta gttattatgg gatgattggg caagaaacaa atggtgctgg
    16141 cgggatattc aaagcttttc gtaccgttcc agtggttttg gcaatcgttg aagacatgaa
    16201 gcgtttatgt ccaaatgctt ggctgattaa tttcgcgaac ccaagcggga tggtgacaga
    16261 agcagttatc agatatggca aatgggataa agtgatcgga ttatgcaatg tgccagtaat
    16321 ggcgatgatg acagaaccaa caatgcttgg caagaaaaaa gaagagctga tctacaagtt
    16381 tgccggtcta aatcacttcc attggcacaa agtagcagat aataaaggaa atgaccgcac
    16441 ggcagaattg attgatcgtt tatacgatga agacaatgga ttgccgaaaa atatctttga
    16501 catcccgttt ttcaaagaac aattaaaaca aatgaacatg atcccttgtg gctaccaccg
    16561 ctattactat cgtgaagaag aaatgctgga acatgcttta gaagaatatc aaacgattgg
    16621 tacaagagcg cagcaagtga aagaaacaga agcagagctg tttgaattat acaaagatcc
    16681 agaattggat cataaacctg aacaattgca aaaacgaggt ggtgcttatt attcagatgc
    16741 tgcctgtgaa acgattgctt cgatctatgg aaataaagaa acacagatcg tggtatctac
    16801 aaagaatgat ggagctgttc ctgatctgcc ggcagattgt gtagtagaag tcactgccta
    16861 tgttggcgca caaggcgcac gaaatgtagc gtttggttcc cttcctgctg ctgaaagagg
    16921 ctggttgcaa gtaatgaaga atatggaatt gctgacgatc gaagcagccg tgactggtga
    16981 ttatggaaca gctttgcaag cgtttacgat caatccgctt atacgatcag gaaagacagc
    17041 aaaacggatc atggatgagt tgtttattgc acatcagcag tatttaccgc aattcaagga
    17101 aacaatcagc cggttaaaag cagaaggaat cgaagtccaa gatgaactgg caagagaatt
    17161 atcaagcaat acacatgtaa tggaggaagt atgatgggat tcagaaaaga ttttttatgg
    17221 ggcggagcta cagcagccaa tcaatgcgag ggcggttatg atgaaggcgg acgtgggtta
    17281 gcgaacgtag atgttgtgcc aatcggagaa gaccgttttc ctgtcattac tggaaaaaag
    17341 aaaatgtttg aatttgatga aaatcatttt tatccagcaa aaattgcgat cgatatgtat
    17401 catcattata aggaagatat tgctttattt gcagaaatgg ggttcaagac ttatcggatg
    17461 tccattgctt ggagtcgtat ttttccaatg ggcgatgaaa aagagccaaa tgaatctggg
    17521 ttgaaatttt atgaggatgt ctttaaagaa tgtcaaaagt acgggatcga gccgcttgtg
    17581 acgattacac attttgattg tccgatgcat ttgatcaaag aatatggtgc gtggcgttcc
    17641 agagaactcg ttggttttta tgaaaatctg tgccgagtca tcttcaatcg ctataaagga
    17701 cttgtcaaat attggttgac attcaatgag atcaatatga tccttcatgc accattcatg
    17761 ggcgcagggc tgtattttga agaaggagaa aatgaagaac aaatcaaata tcaagcggca
    17821 catcatgagt tggttgcaag tgccatcgca acgaagatcg ctcatgaagt agatccggag
    17881 aacaaagtag gctgtatgct ggcagcagga gcatattatc catacacttg caatcctgaa
    17941 gatgtttggg cttctagaaa gtcagatcga gaaaattatt tcttcattga tgtccagtca
    18001 cgaggagaat atcccgctta tgcattgaaa gaaatggaac gaaatggcat tcagatcaaa
    18061 atggaacctg gggatgccgc attgctgaaa gaacatactg ttgattttat ctccttttct
    18121 tattattctt ctcgagtttc gactactgac aacgaactct tggaacagac tgcaggaaat
    18181 atctttgctt ctgtcaaaaa tccatatctg gaagcaagtg aatggggttg gcaaattgat
    18241 ccattaggct tgagaataac gatgaatgat atttatgatc gttatcaaaa accactattt
    18301 attgtagaaa acggcttagg tgcagtcgat acgcccgatg agaatggtta tgtggaagat
    18361 gattatcgaa tcgactatct ggcagcacat atccaggcaa tgaaagatgc agtagaatta
    18421 gatggagtcg atctattagg ctatacgact tggggatgta ttgatttagt atcagctggt
    18481 acaggtgaga tgaagaaaag gtacggattc atttatgtcg atcgtgacaa cgaaggaaat
    18541 ggcacattag cccgttcgaa gaagaaatca ttcaactggt ataaaaaagt aattgattca
    18601 aatggagaaa atctttcgaa cgattgatca atgatttata aaagtctatt gtttttcagc
    18661 ggatttttcg agtataataa agctattcga gaaacgcaag cagaacaata gacttttttt
    18721 cgcattggct gtaaagtatg cttacttgat taagtaaagg agaatctaca tatgtatgat
    18781 gtaatcgtta ttggcgcagg gcctgctggg atgactgctg ctttatatgc ttcacgttca
    18841 aacttatccg tattgatgat cgaacaaggc gctcctggcg gccaaatgaa caatacggca
    18901 gaaatcgaaa actatcctgg tttcgattca atcatgggtc ctgatctagc ttataagatg
    18961 tatgaaggtg tttcaagatt tgggacagaa aatgcttatg gaatcgtgca agatatcaag
    19021 gatcacggca gccacaaaga agttatttgt gaagataaaa cttacgaagg aaaaacagtc
    19081 attatcgcaa caggctgtat ccaccgtaaa ttaggcgtac ctggcgagga agaatttgct
    19141 ggacgtggcg tttcttactg tgcagtttgt gatggtgcat ttttccgtaa caaacgtcta
    19201 gtagtgatcg gaggaggaga ctcagcagta gaagaagcca tctatttgac acaatttgct
    19261 tctgaagtag tcatcgtcca ccgtagagat gaattacgtg cacaaaagat catccaagac
    19321 cgtgcatttg cgaatgaaaa aatttccttt atgtgggata cagtcgttga cgaaatcgtt
    19381 ggaaatgaaa tggtagtgac aggtgtgaaa gcacgtaatg tcaaaactgg caatgagttt
    19441 gatttggcag cagacggagt attcatctat gtaggattgg atccattaac tgcaccattt
    19501 agagaagctg ggttgacgaa cgaagccggc tggattccaa cagacaacga aatgaagacg
    19561 aatataccag gcgtttttgc catcggagat gttcgtgaaa aagatttgcg acaaatcact
    19621 actgctgttg gtgatggtgg gattgctgga caacaagtgt ataaatactt ggaatcttta
    19681 gaagaaacaa ctgcataagt ttaaaaagag tgaaagaacg gtttcaattg ttcttttact
    19741 cttttttttg cgtgaaatct actgaatccg atttatgcga atacttgtaa ccgtgcttga
    19801 taaaagaatc ttttcttgat ttaagcgttt tttggtcctc atactttcat atctaataag
    19861 tgaatgctat acttattaag aaccatattt cagaaagagg tgttattttc atgtcttggg
    19921 aacaagtgta tgaacaatgg gtacatgaag aaaatttaga agaaaactta aaaaaacaat
    19981 taaatgatct gggtgaagat cctgaaaaac ttgaagatgc tttttatgca ccgttggaat
    20041 tcggtactgc aggcatgcgg ggaatcttag gacctgggat caatcgaatg aacatctata
    20101 cggtaagaca agcaacagaa ggacttgcac gtttcatgga tacacaaggt gaagaaacaa
    20161 aacgccgagg tgtcgctatc gcttatgact cacgccatca atcaccagaa tttgccatgg
    20221 aagcagccaa aacattagca catcacaata tcccttctta tgtattcgaa agtttacgtc
    20281 caacaccaga gctttctttt gcagtccgtc atttgaagac gtttgcggga atcatggtaa
    20341 ctgcatccca caatccagca gcttacaacg gatataaagt ctacggagaa gatgggggac
    20401 aaatgcctcc tgcagacgca gatgcattga cgaaatatgt ccgtgaagtc agcaatccgt
    20461 taaaagttga agtattatct gacgacgaag ctgaacatag cggattgatc acgatcatcg
    20521 gagaagaagt ggatgccgct tatctagaag aaatcaaagc agtaacgatt gatcatgaat
    20581 tggtggaaac aatgggtaaa gatttgaagc ttgtgtacac accacttcac ggaacaggaa
    20641 aaatgttggg cgaacgtgcg ttgaaacaag ctggattcga acaattcgta ctagttccag
    20701 aacaagctgt cgcagacccg gatttcacta cagtcaaatc accgaatcca gaagaacact
    20761 ctgctttcga gtatgcgatg cgacttggcg agaaagaagg cgctgactta ctgattgcaa
    20821 cggatcctga tgcagaccgt ttaggcgcag ccgttcgttt gccaaatggc tcctatgaag
    20881 tattgacagg aaaccaaatc ggagccctgt ttgctcaata tattttggaa gcacaccaat
    20941 cgcgaggcac tttacctgaa aatgcagcgg tattgaaatc aatcgtttct agcgaattgc
    21001 ctacagcaat tgcggaacac tatggggcta ccatgttcaa tgtattgaca ggattcaaat
    21061 tcattgctga aaaaattcaa caatttgaag aagatcattc ccatactttt atgttcggat
    21121 tcgaagaaag ttacggttat ttagttaaac ctttcgttcg cgacaaagac gcgattcaag
    21181 cattgctctt attagcagaa gtagcagctt actataaaaa acaaggcaaa acattgtatg
    21241 acggcttgca aacgattttt gaaacatatg gctactacgc agaaaaaacg atttctgtga
    21301 caatgagcgg acaagaaggc tctgcaaaaa tctctgcttt gatggaaaaa ttccgtgaag
    21361 aagcaccgac agaatttgcc ggagcaaaag tcatccaaac agaagacttc aaagagttga
    21421 cgagaacaga ccgtgaagga aacgtagaaa aactaacgac accgccatct gacgtattga
    21481 agtatacgct ggaagaaaat ggctggatcg ctatccgtcc ttcaggaact gagccgaaaa
    21541 tcaaatttta tatcggtgta aaaggaaact cttcagaaga cgcagctgaa aaagtagccg
    21601 cttatgaagc gattatcaaa aaaatgacag aagaataaaa aaacttgaga ctgatggaaa
    21661 aagtggtaaa ctttagaagt cagtcttttt tcaagttgga ggtgaatgga ttgccagaca
    21721 cgcaaaaaac aaaagtagag aaagtcagcc aactattcaa aatgttgagt gaccccactc
    21781 gtctcaaaat tctgctgtat ctgaaagacg gggaacaaaa tgtgacagca atcacccaag
    21841 cagtagaaat ggaacaatct gctgtatcgc atcaactgcg tttattaaga gaaaaccatg
    21901 tcgtcaagtc ccatcgtgag ggaaaagcga ttttgtatag tcttgatgat tctcacgtac
    21961 tggatatttt gaaccagacg ctcaaacatg tggaacatca ataacgatag gtgcaaatag
    22021 agacaaactg gactgtatca acgaatcttc ttcgctgaca cagtccagtt tttttaagaa
    22081 aaagacaaga aaaactgtta gtctgtttct tcggtggttt cagttccata ataactatga
    22141 tcttctaggt ctaaagcatt caaaataagt gaagctgttt cttcgataga taaagaagcg
    22201 acattgatta ctacgcagcc caatttttca taaagatcat tcgcaaaatc gagttcagct
    22261 cgtatttttt cgatatcgga ataagcagta tcaggattta atccgtaaga gcgcatccgt
    22321 tctttacgga tattgtttaa aatatctggg ttattcgtca gtcccacgat ttttttagga
    22381 tcgatctccc aaagctgttt gggaatatgt gcttgtggga tcaaaggtag attggcaacc
    22441 tttaaatttt tgttagctaa aaacaagctc aaaggcgttt tggaagttct ggatacgcct
    22501 agcaaaacga catctgcttc tagaaaccca cgaggatctt tcccgtcatc gtattttaca
    22561 gcaaattcca ttgctttgat ccgtttgaaa tagttctcat tcaataaatg aagggcgcca
    22621 ggttgccgaa tgggcttgat accagttaag cgctcgattt ctgatatcgg cggagtcatc
    22681 acatcaaaac taaataattg atgttcttca caaaaagaac gcgtcatctc gatcaattct
    22741 tgattgatca atgtgtgtag gacaagggct ttttctttta gtgcatcttg cagtgcctgc
    22801 atcaatgttt tctcatctgt cacaaatgtt ctgcggaata aattgaactc aacggtagga
    22861 tattgggcca tagtggcttg cgctaatttt gtcgcagttt ctccagcaga gtcagagatg
    22921 acaaaaaaag taatgatttc tgtagaatcg gaagacatgg ataaaacctc acttgcattt
    22981 tttttatgtt tattatacca tactctagaa tgtgtacttc gtaatcattt tgatttggag
    23041 gaataagtca tgaaaaaaca gacattgatt gaacaatcac tagaaacatt gaaaaataac
    23101 ggttttaaat atactaaaaa aagagaagca ttgttaactt atttagtgaa gcgcaatcgc
    23161 tacgtatccg ctaaagaagt ttttgactat atgaatcagg aattcaaagg agtaagttac
    23221 gatacgattt atcgaaatct ccatgatttt gcagaaatcg atttactgga agaaaccgat
    23281 ttaaatggag agatgaagtt tcgttttcat tgctgtcaag gggaaatcgg ccatcaccat
    23341 cactttatct gtacggtgtg cggaacaacg aaagaaatcc atatgtgtcc aatgaattat
    23401 ttcgaagaac agctcggtgg atgtacgatc gaagggcata gattcgagat tttcggaaga
    23461 tgtgaaaatt gtcaataagg atttaaataa aataacattt gataatttta aaaaaaagca
    23521 agatttcctt gacggtcaaa acagcattag atataatatt tacaggacag tcttgttttt
    23581 tgagatatat ttcaataaca attacggtta ctttttaagc tcggagggag ggaattaaca
    23641 tgtcaaaaac agtcgttcgc aaaaacgaat cacttgacga tgctcttcgt cgcttcaaac
    23701 gttccgtgtc aaaagcgggt actttacaag aatctcgtaa acgtgaattc tacgaaaaac
    23761 caagtgtaag acgcaagaaa aaatctgaag cagctagaaa acgcaaaaaa ttctagttct
    23821 gtgatgaatt ggagttggta gtgtgtcact actaagtaga ttaaacgatg acatgaaaac
    23881 agcgatgaaa gcgaaagata aggaatcttt acaagtcatc cgaatgatca agtcatctat
    23941 acaaaacgag cagattaaag aaggtcacga cttgacagaa gaagaagaat taacggtgtt
    24001 gtctcgcgaa atgaaacagc gacgtgattc tttgcatgag tttgaagaag caggacgtga
    24061 cgatttagct gaaaaagtaa aaagtgaaat tgtgatagtc gaaaaataca tgccggaaca
    24121 actttccgac gaagaaattc gacaacttgt tcaagaagca atcacacaaa ctggtgcttc
    24181 atcaatgaaa gaatttggca aagtcatggg tgcgatcatg cctaaagtca aaggaaaagc
    24241 agatggaaac caagtaaatg ccattgtgaa agaactatta caatcttaat tttatcattt
    24301 aaaggctctt cgtcaatgag tgttggtgaa gaa
//
LOCUS       DBBGRF010000043        24131 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000043 DBBGRF010000000
VERSION     DBBGRF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.043"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..623
                     /locus_tag="ACIZD4_001979"
     CDS             <1..623
                     /locus_tag="ACIZD4_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HGC5990889.1"
                     /translation="ATINEEVNIDRLKTMYDGYDGDRVIEIRFIDPRRFTVQQRNFIY
                     ALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLKDESNTTVSDANVLANIILDFIF
                     EHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKTGADIDHFDKALGRRKRKEVDHS
                     EYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQETIKKLRIGV"
     gene            626..853
                     /locus_tag="ACIZD4_001980"
     CDS             626..853
                     /locus_tag="ACIZD4_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990890.1"
                     /translation="MINLNAVAFAQTWHTKYKKMSPRDKLFLEIMTFAFIGTQAEQSD
                     ISVEKIKTNRLVNGITETCYQYTIIVVDEEE"
     gene            856..1683
                     /locus_tag="ACIZD4_001981"
     CDS             856..1683
                     /locus_tag="ACIZD4_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HGC5990891.1"
                     /translation="MAERRMFAKTIIDSDAFLDMPLSTQALYFHLSMRADDDGFINNP
                     KKIQRMVGCGDDDLKLLMAKRFILVFESGVIVIKHWKIHNYIRNDRYKPTLYQDEKAL
                     LADKDNKAYTFAEELSKHDEKLGIPDDNQAVYQMDTQVRLGKDRLGKDSKEIKDVTPS
                     KKSKAKPICHKYGEYKNVLLSDEQMEKLKTEFPNDYQERIERLSEYCESSGKTYKNYL
                     ATIRSWARKEKNESKSASSGYKRTGRREKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            1695..1964
                     /locus_tag="ACIZD4_001982"
     CDS             1695..1964
                     /locus_tag="ACIZD4_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990892.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGIKKDRS
                     SWSKLRYYFALYIDATQLRNLAYTKLLFADCVKGLQKHLSELEQV"
     gene            1969..2133
                     /locus_tag="ACIZD4_001983"
     CDS             1969..2133
                     /locus_tag="ACIZD4_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990893.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGERRDG"
     gene            2126..2428
                     /locus_tag="ACIZD4_001984"
     CDS             2126..2428
                     /locus_tag="ACIZD4_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990894.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            2425..2586
                     /locus_tag="ACIZD4_001985"
     CDS             2425..2586
                     /locus_tag="ACIZD4_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HGC5990895.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            2583..2894
                     /locus_tag="ACIZD4_001986"
     CDS             2583..2894
                     /locus_tag="ACIZD4_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990896.1"
                     /translation="MSVDKKATMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK
                     C"
     gene            2888..3178
                     /locus_tag="ACIZD4_001987"
     CDS             2888..3178
                     /locus_tag="ACIZD4_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990897.1"
                     /translation="MLDMKIEDYRITSDSRNIVLSKVRRDEEGNIRYTEAKEESRADI
                     GYFQTVSSCLKAIQRDYVLSEERTIKSIIEYKKALENITRQFEQACEIEEEK"
     gene            3178..3495
                     /locus_tag="ACIZD4_001988"
     CDS             3178..3495
                     /locus_tag="ACIZD4_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HGC5990898.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGSGVR
                     TSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     DRE"
     gene            3492..3665
                     /locus_tag="ACIZD4_001989"
     CDS             3492..3665
                     /locus_tag="ACIZD4_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990899.1"
                     /translation="MMMPKEIYSDALRGARNQLKMAKRTYEIRPTIENERRVKAIRRR
                     CSIYGELQKEDSK"
     gene            3662..4075
                     /locus_tag="ACIZD4_001990"
     CDS             3662..4075
                     /locus_tag="ACIZD4_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HGC5990900.1"
                     /translation="MIPRFRAWNKKTQSFIDYGDLVLDLRSGKIYAGDIGLVESTIDV
                     TDQIELMQSTGLKDKNGIEIFEWDIVSVSVRNGFDYLDNKVCVVKNSIGHSGLVCATV
                     DEDLEYQIFNTELFEEYTYEVIGNIWENSELLEVE"
     gene            4072..4410
                     /locus_tag="ACIZD4_001991"
     CDS             4072..4410
                     /locus_tag="ACIZD4_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990901.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            4411..4632
                     /locus_tag="ACIZD4_001992"
     CDS             4411..4632
                     /locus_tag="ACIZD4_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990902.1"
                     /translation="MFKIAFYLFDYKDDSFKKVYFHHWNDSKPVFTKNKRRAQEYFDE
                     RSANKDIVQLKKAESPSAKTLSIRLEEKE"
     gene            4629..4934
                     /locus_tag="ACIZD4_001993"
     CDS             4629..4934
                     /locus_tag="ACIZD4_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990903.1"
                     /translation="MNIKVYLKRNLARFPRSWDTNSYPFEVEEESYLMSANMIEITRD
                     DADEFDKKRSCYFVPNPMYTAVIEDYHISDRFILIDLERPKKRVKQYRRCGFSTKKW"
     gene            4958..5161
                     /locus_tag="ACIZD4_001994"
     CDS             4958..5161
                     /locus_tag="ACIZD4_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HGC5990904.1"
                     /translation="MNTRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASETIRKFGISILNDDRKWEEMR"
     gene            5158..5463
                     /locus_tag="ACIZD4_001995"
     CDS             5158..5463
                     /locus_tag="ACIZD4_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990905.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKARKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVARLVDMEVINNGIKN"
     gene            5447..5740
                     /locus_tag="ACIZD4_001996"
     CDS             5447..5740
                     /locus_tag="ACIZD4_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990906.1"
                     /translation="MELKIDKVTFEEPAFQEMDERIAELVEKKQDELIALLEKKYQFP
                     KYMNKMQAAKYLGVSYNTMMDKYVPAGLKMGIVNGVIRISKEECDRFMKEHQK"
     gene            6000..6416
                     /locus_tag="ACIZD4_001997"
     CDS             6000..6416
                     /locus_tag="ACIZD4_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HGC5990907.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKYGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            6675..6827
                     /locus_tag="ACIZD4_001998"
     CDS             6675..6827
                     /locus_tag="ACIZD4_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990908.1"
                     /translation="MKLSIEGTSGEIKELLQAIGGSKEQNIKIDDIYKESRDFLINGQ
                     AFAPSF"
     gene            complement(6817..6993)
                     /locus_tag="ACIZD4_001999"
     CDS             complement(6817..6993)
                     /locus_tag="ACIZD4_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990909.1"
                     /translation="MLTNEQRAHDLAIATLPFVRDIVKSQIIEGKDAKFDAYFEYIKL
                     YNQFLSAVSEDFKN"
     gene            7374..7541
                     /locus_tag="ACIZD4_002000"
     CDS             7374..7541
                     /locus_tag="ACIZD4_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990910.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKH"
     gene            7567..7911
                     /locus_tag="ACIZD4_002001"
     CDS             7567..7911
                     /locus_tag="ACIZD4_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HGC5990911.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            7916..8197
                     /locus_tag="ACIZD4_002002"
     CDS             7916..8197
                     /locus_tag="ACIZD4_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990912.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            8300..8614
                     /locus_tag="ACIZD4_002003"
     CDS             8300..8614
                     /locus_tag="ACIZD4_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HGC5990913.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            8592..10286
                     /locus_tag="ACIZD4_002004"
     CDS             8592..10286
                     /locus_tag="ACIZD4_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HGC5990914.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYNIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            10306..11484
                     /locus_tag="ACIZD4_002005"
     CDS             10306..11484
                     /locus_tag="ACIZD4_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGC5990915.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            11447..12133
                     /locus_tag="ACIZD4_002006"
     CDS             11447..12133
                     /locus_tag="ACIZD4_002006"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HGC5990916.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            12133..13293
                     /locus_tag="ACIZD4_002007"
     CDS             12133..13293
                     /locus_tag="ACIZD4_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGC5990917.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            13303..14178
                     /locus_tag="ACIZD4_002008"
     CDS             13303..14178
                     /locus_tag="ACIZD4_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990918.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            14175..14486
                     /locus_tag="ACIZD4_002009"
     CDS             14175..14486
                     /locus_tag="ACIZD4_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990919.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            14476..14829
                     /locus_tag="ACIZD4_002010"
     CDS             14476..14829
                     /locus_tag="ACIZD4_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HGC5990920.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            14819..15220
                     /locus_tag="ACIZD4_002011"
     CDS             14819..15220
                     /locus_tag="ACIZD4_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990921.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            15213..15617
                     /locus_tag="ACIZD4_002012"
     CDS             15213..15617
                     /locus_tag="ACIZD4_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990922.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            15629..16234
                     /locus_tag="ACIZD4_002013"
     CDS             15629..16234
                     /locus_tag="ACIZD4_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC5990923.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            16254..16616
                     /locus_tag="ACIZD4_002014"
     CDS             16254..16616
                     /locus_tag="ACIZD4_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990924.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            16619..16801
                     /locus_tag="ACIZD4_002015"
     CDS             16619..16801
                     /locus_tag="ACIZD4_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990925.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            16818..20237
                     /locus_tag="ACIZD4_002016"
     CDS             16818..20237
                     /locus_tag="ACIZD4_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HGC5990926.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            20288..21025
                     /locus_tag="ACIZD4_002017"
     CDS             20288..21025
                     /locus_tag="ACIZD4_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGC5990927.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            21035..23326
                     /locus_tag="ACIZD4_002018"
     CDS             21035..23326
                     /locus_tag="ACIZD4_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGC5990928.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIIEGRIIQCYVDENRAKQRLRIYYAKTSVIGNMIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHETRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVEDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVNNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            23350..>24131
                     /locus_tag="ACIZD4_002019"
     CDS             23350..>24131
                     /locus_tag="ACIZD4_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HGC5990929.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSGNPNLLSKLSYDLIE
                     NQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLP"
BASE COUNT         8676 a         3555 c         5174 g         6726 t
ORIGIN      
        1 gtgcaaccat caatgaggaa gtgaacattg atcgactaaa gacgatgtat gacggctacg
       61 atggtgatcg agttattgaa attcgtttta ttgatcctag acgtttcaca gtacagcaac
      121 gaaacttcat ctatgcactc ataggcgata ttttcatcga tacaggcatg ccaacggact
      181 tctggaagga attcttttac ttccgctttg aaggtgtcac agggcgcaaa ataagcctca
      241 aagatgaatc gaatacgact gtgagtgatg ctaacgtctt agcaaatatc atcttagatt
      301 tcatctttga acatcatatt cctttcaaag aaggctatga gattttacca gcgaatcaag
      361 aatattactt ctacaaatgc atcacaaaaa gagtctgttg catctgtggc aaaacaggag
      421 ctgatatcga tcactttgac aaagcgctag gaagacgaaa gcgcaaagaa gttgatcatt
      481 cagagtacac atttgcagca ctctgcagaa tccatcacac ggagaaacac aagataggtg
      541 tgatcaattt caaaaataaa tatcaaatca aaggaatcaa gttaaaccag gagacaatca
      601 agaaattaag aatcggggtc taatgatgat taatttaaat gcagtagcgt ttgcacaaac
      661 atggcacact aagtataaaa aaatgagtcc aagagacaaa ttgttcttag aaatcatgac
      721 atttgctttc attggcacac aagctgaaca aagcgatatt agtgtcgaaa aaattaagac
      781 caatagatta gttaatggaa ttacagagac ttgttaccag tacacgatta tcgtcgtgga
      841 tgaggaggaa taattttggc agaaagaaga atgttcgcaa agacaattat tgattctgat
      901 gcattcctag atatgccttt atcgacacag gcattatatt tccatctatc aatgcgcgca
      961 gatgatgacg gatttattaa taatcccaaa aaaatacaac gtatggttgg ttgtggtgat
     1021 gatgatttaa aactgcttat ggcaaaaaga ttcatcttag ttttcgagag cggtgtgatc
     1081 gtcattaagc attggaaaat acacaactat attcgtaatg atcgttacaa acccacgtta
     1141 tatcaggatg aaaaagcttt actagcagac aaagataaca aagcttatac atttgcagaa
     1201 gagctttcta aacatgatga aaaacttggt ataccagatg acaaccaagc ggtataccaa
     1261 atggatacac aggttaggtt aggtaaggat aggttaggta aggatagtaa agagataaaa
     1321 gatgtaacgc cttcgaaaaa atcgaaggct aagcccatct gtcataaata cggagagtat
     1381 aaaaatgttc ttttgtcaga tgagcagatg gagaaactca aaacagaatt ccctaatgac
     1441 taccaagagc gaatagaacg gctatctgag tattgtgaat catcaggtaa gacttataaa
     1501 aactatttgg caactattcg aagctgggca agaaaagaaa aaaatgaatc taagagcgca
     1561 agcagtggat acaagcgcac agggagacga gagaagcttc ctgagtgggc aatcgaccaa
     1621 gaagcctatc ttaagaaaaa agcgctagaa cgagctaata gacaatcaaa agcaccattc
     1681 taagaggtgg aaaattgaaa atcgattatc tagaactaat taatgaaata gcaaagtata
     1741 aaactggtga ggaaatagaa atcctgagag acgtatatga tcaactcgaa gaagctggaa
     1801 tcgaaggaat taagaaagac cgttcgagtt ggagtaaact cagatactat ttcgcacttt
     1861 atatcgatgc aacacaatta agaaatttag cttatacaaa attactattt gctgattgcg
     1921 ttaaaggatt gcaaaaacat cttagtgaac ttgagcaggt gtaatcagat ggatctaaaa
     1981 acatttacag cacagatcga actaatgcat caagaagctt taagacaaag cgcctcgtac
     2041 gaagacaagt ggctcaacac gttccatggt ggacgtgaga gcgcacttga tcaagtactc
     2101 aaattattga aaggggaacg tcgggatgga taagaaagcg gcaatgcagc gaattatcga
     2161 attgacttat tcagaagatt ggcaaaatga caaagaagct gcttcagaag tgatgaggct
     2221 tggaagagcg atgtgggcag acaagagcaa caagccaaga ccacgaaaaa tcgcaatttg
     2281 gcacggtgac aaacttctag tgatagggac agctgaacag ttagcaagtc tcacaggctt
     2341 gcacgagaaa atcgtgagga aaagagcaag gtgtggctac acagacgcta agaagagaac
     2401 gtttagatac gtggaggaat catcatgaca acagaagaag tgattcaaat gcgtattcga
     2461 agccttcagc gtgagattga cgatctggaa cgaacaaagg cagtgatggt caatgaaacg
     2521 gcgaggaagg caatcgattt gcacatagaa aatttaagaa gggaaattcg tagattggag
     2581 gaatgagcgt ggataagaaa gcgacaatga aacgaatcat cgaactgaca cattctgaga
     2641 attggcaaga agacaaagaa atagttgcag aagtccaaaa gctcggtaaa tcaatgtgga
     2701 ctgaaaagcc caaacggaga acgccgagaa agattgcaat ctggcatggt gatcgaattc
     2761 tagtaacggg taccgctaaa cagttatctg aaattactgg tctgagcaaa aacatcatct
     2821 gggatagagc taggagctta tggattgatt caaaaggacg acagtttagg tatgtggagg
     2881 agaaaaaatg ctagacatga aaatcgaaga ttatcgaatt accagtgatt ctagaaacat
     2941 tgtcctatcg aaggtaagac gagatgagga aggaaatatc cgctacaccg aagcaaaaga
     3001 agaatcacga gcagatatcg gatactttca aactgtctca tcgtgtttaa aggcaataca
     3061 acgcgattac gtgttaagtg aagaaagaac gataaaaagt attatcgagt acaaaaaagc
     3121 gttagaaaac atcactagac agtttgaaca ggcatgtgag attgaggagg agaaataatg
     3181 gatctcatta cacaatacag tgacatcatc ctcaagaaaa tcatgatgaa gattcagaaa
     3241 gacaaaaaat caaaagaacg agcggaatta gttaagttag aaatggctga aacaggatca
     3301 ggagttcgaa catcgaggca ttggaaagca gcagcaaaca ttgaattcta ttacaacgaa
     3361 attcaaaaag ggttcgatca gatgcgtgag ctggatcggc aaacaaattg gagcaagaaa
     3421 cttcatcaag atcgtttcaa atttgtagag aaatataaag agatattaga cgaatacatg
     3481 gaggacagag aatgatgatg ccaaaagaaa tctattcaga tgcattaaga ggtgctagaa
     3541 atcaattgaa aatggcaaaa agaacatacg aaattcggcc cacaatcgaa aatgaacgca
     3601 gagtaaaagc aattcgccgt agatgttcaa tttacggcga gttacagaag gaggacagca
     3661 aatgataccg agatttcgag cgtggaataa gaaaactcag tcatttattg attatggtga
     3721 tttggtttta gatttgagaa gcggaaaaat ttacgctggg gacattgggt tagtggaaag
     3781 caccattgat gtgactgacc aaattgaact catgcaatca acagggctga aagataagaa
     3841 tggcattgag attttcgagt gggatattgt atcagtcagc gtgcgaaatg gattcgatta
     3901 tttagataat aaagtttgtg ttgtcaaaaa ttcaatagga cattcgggat tagtgtgtgc
     3961 cactgttgat gaagatttag agtatcaaat ttttaacaca gagctgtttg aagaatacac
     4021 gtatgaagtc atcggaaata tttgggagaa tagcgagtta ttggaggtag agtgattatc
     4081 ttagctactg actacatcga ttctttaaaa gatgaaaatg ggaatgtccc agcattgcta
     4141 aattgtggaa ttaaaagcaa gaatagaatc attttgttac ggatatcggc tgatttagca
     4201 aaatatcttt atctgagcaa gacagcagta tattacactg cggctacacg ttatcagtac
     4261 aagggaaaaa caatcagtca ggattattat gatcgtttaa tcagtcctga catgcatgga
     4321 aaatcaaaat cagcgatcaa gttatttggc gcaatagaga tatatgccga tgattttcca
     4381 aatttatggt tgaaggagga agcggaatga atgttcaaaa tagcatttta tctgttcgat
     4441 tacaaagatg attcgtttaa gaaagtttat ttccatcact ggaatgatag caagccagtt
     4501 tttacaaaaa acaagaggag agctcaggag tattttgatg aaagatcagc aaataaagat
     4561 atagtgcagt taaaaaaagc agaatcacca tctgcgaaaa cattgtcaat tcgattggag
     4621 gaaaaagaat gaatattaaa gtttatttaa aaagaaattt ggccaggttt cctcgaagct
     4681 gggatacaaa ttcctaccca ttcgaggtag aagaagagag ctatctaatg tctgctaaca
     4741 tgatagaaat tacaagagat gatgcggatg agtttgataa aaaaagatca tgttactttg
     4801 ttccgaatcc aatgtatacg gctgtaatag aagattatca tatatccgac agatttattc
     4861 tgattgatct agaaaggcct aagaaacgag ttaaacagta tagacgttgt ggattttcaa
     4921 caaagaaatg gtgataacaa aacagaggtg aagaaaaatg aacaccagac atcgcagaat
     4981 aacaaaacta agaaaacagg aactgaatgt actaaagaca aagtttgaaa aagaatatgg
     5041 aatttcagca gaagaaacat ataaagtggc aagtcagtgt gttgctgatg cgagtgagac
     5101 tattcgtaag tttgggattt cgatattaaa tgatgatcgt aaatgggagg aaatgagatg
     5161 aaactaaaag acggatttta cgctagtagt catggtatcg gcggtttaat gctagatatg
     5221 ccgacaaaga accctaaagc acgtaagaaa ccaaaattca aagtcggtga catggttcgc
     5281 tgcgaagcag aaggattcat ctatccattt cgtggatatg tagagcatct ctataatcac
     5341 tcagcaatca ttcgcattga aaacacgatg gaatgtgaca agcggttagc gaaaagcaaa
     5401 gagaatttag ctgtagcgag attggtggat atggaggtta taaacaatgg aattaaaaat
     5461 tgacaaggta acgtttgaag aaccagcatt tcaagaaatg gatgaacgaa ttgcagaatt
     5521 ggtcgagaaa aaacaagatg aattgattgc tttgctagaa aagaaatacc aatttccgaa
     5581 atatatgaac aaaatgcaag cagcaaaata tcttggtgta agttacaaca cgatgatgga
     5641 taagtacgta ccagctggtt tgaaaatggg tatcgttaac ggcgttattc gtatcagcaa
     5701 agaagaatgt gatcgtttta tgaaagaaca tcaaaaataa aataaaaaaa cgtttagccc
     5761 cttagctaaa cgcacaatta taatttacct gacagttaat tataacaaaa ttgcggaggt
     5821 tgaggaatgg cggaatgaaa aagacaataa aaacagaaga agcatatatt gaagtatttg
     5881 acacaccagc atgctaagtc gagaagtgta actcggcaaa taaaaaaagc cggatcgctc
     5941 cgactgttct aataaattcc acaaatttat tatatcacat aaaggagcgg tttgacttga
     6001 tgcaattgtt acgagaggta gatttcaaac agacaagatg taatgcgaga gatgtgctga
     6061 agaactttcg gcgtttggag cggatggcag gtcgctcttt gatagatatt aagtcgccga
     6121 ttattacgga catgccaaag gcaccgaaat atggaaacaa ggcagaagac gcgatcattc
     6181 agatgatgga tatagaagcg gagagagatg cgattttagc ggctttgatg gctcttagtc
     6241 tgattagtcg tcagatactc tactatagct tctgtgacgt aaataagcac tctaattatg
     6301 aaataggtca attgatacga ggatacggag agaagaatgt agagaagctg aaatctatcg
     6361 cgctgatcga atttgctgaa gcatacaaaa aaggcgtgtt agttcagtat cgttgatttt
     6421 gtagggtttt tgtagggata gtgtagggtt tttgagtgtt ttaacgtgat attatgatag
     6481 tgtcgaaaga ttaggaaaca ggatcgacaa aataaaatgt aagggaggga atctccctca
     6541 tcgttttaaa ttaagcttcg ataggcagca acggaaatat taagaataag gatgtgaatt
     6601 tcaactcctc ctgattgttc ttattatcta tcatccgttg ctgtctatta atttatgtat
     6661 tggagggtaa gaatatgaaa ttatcgattg aaggtacttc aggagaaata aaagagttgc
     6721 tccaagctat tggtggtagc aaggagcaaa atataaaaat tgatgatatt tataaagaaa
     6781 gtagagattt tttaattaac ggtcaagctt ttgctcctag tttttaaaat cttcagaaac
     6841 agcggaaaga aattgattat aaagctttat atattcaaaa tatgcatcaa attttgcatc
     6901 tttcccttca attatttgag atttaacaat atctctgaca aaaggtaatg ttgcaattgc
     6961 taaatcatga gcgcgttgtt cattggttaa catagttttc accttcgtat atttatttca
     7021 gcggaccact cgctgataaa taaaattata cacttagtat ttattttcac aatattaatt
     7081 tgtcactgtg gcggagggta gacgcttaaa ataagttcaa tacgtcgagg gatagcctta
     7141 acgttttatg atttgaccat gcaatgttcg attcattgcc agcgatttta gcaactgagg
     7201 gttggaaatg ggcgctcaaa gtacacgagc aaggcgaggt cgatagtaat cgatggaatc
     7261 ggtgtaggtt gcttgataga gctataactg catctcattg ttgagatgta gtttttacat
     7321 attagatcac tcgttgagtg gtctttttat tttgcaaaaa ggaggtaaca acaatgtata
     7381 gaccacaata tttagaacag aagtatgaag taatcactgt gcaaaacggt aacggtgaga
     7441 tagtacgaaa gtatagaaga ccaataaaga gcgatacata caaacgaaag gaaagcaatg
     7501 aagttattcc attgtatggc aaaagaatag ctaagcatta aataagattg cgaaaggaga
     7561 cggaacatga ccgaggaatt ctatagatgg ctattacagt tgacaagaga agatcgtttg
     7621 gttaagttct atcagtctcc taaatggcgc aggcttagag agaaagcgat gaaacgagat
     7681 cactatgaat gccaagagtg tagaagacta ggtaagtatc atagagtaga gaacgttcat
     7741 catataaagg aagtcaagga tagacctgac ttagctttag atttagataa tcttatttgt
     7801 ttatgtgttg aacatcataa tgaagttcat ggcagatatc ttacagcatt agataaacaa
     7861 gagaagaaga tagaaagctt tgctaacttc gatgcaagtg aaaggtggta agtgcatgat
     7921 catcaatgat aatggcagag agtatgatac agaaaagatt gaagagtatt catcttatac
     7981 tcagggattg attaaacgtt tgatatacgt tcgctatgta ggtattaggg atctgttatc
     8041 agataactgt tgtagcaaat acaaagtgaa tcaagtaaga gaagcgttga ataaagataa
     8101 taatgttgaa agaataaaaa atgttttcgg atatagcatt gaagagatta attattacat
     8161 tgacttcgct gaagctttca ttccgatggt gagataaccc ccccttaaaa taaatcgcaa
     8221 attttttggg ggtgatgaaa cggagggggc tgtcaggaaa agagattttt tcgaacttta
     8281 tcatgaaagg agggctaaaa tgtttaaaaa cgaattgtct caaaatcgct acagagaaaa
     8341 attacgccgc tctttaataa gccaattgga aagtcagaaa acaaatattg agccattctt
     8401 agataatgtt gatcgttata tcagtttatg ggaaacggcg atatcactgg aagaagatat
     8461 atccgagaac ggcattagac tggagaatgg taaaaagaat gaatcagtag cgttgcttgt
     8521 ttctgtcaac aaacaaatgg gattgatgtt ggataaactt gccattactc ctgaattggt
     8581 aggtgaagca aatgaatcaa ttcctgagtt ataagcatat tgaaaattgg ttcaaagcta
     8641 tagaagaagg cactatcaag gtatgcaaag agcaattatt gctaaaaaat tatctagaag
     8701 aaagagtctt tactagagaa gatatttact tcgataagca gatggtagag gattcaatca
     8761 atataccagc acaatacttt ccattcgaat taattccgtg ggaaaaattt ctacaatgtt
     8821 ttatttatgg tgttcgatgg aaaaaagata aaacactagt gttcaataga tatctttcat
     8881 taatgggacg tggtaatggt aaaactggtt ttgcttcttg gaacaacttc tttctactaa
     8941 ccgctaaaca cggtattaaa aattataata ttgatatcta tgccaataat gaaagccaag
     9001 caaagactag ttttgatgat gtatttaaag taattaaaga tcatcctgat ttagataaaa
     9061 aagtatttaa agctacgaag gaagttattc aaaatatcgc tacaaacagc aaacttcgtt
     9121 ataacacggc aaatgctaga acaaaagatg ggaagcgacc aggtgcaaac cgctttgatg
     9181 aaattcacga aaatgaagat tattcaatga taaatgtggc tacttctggt ggtggtaaaa
     9241 ttcgagatta tagagaattt tatgatacaa ctaatggtca tgttcgtggt ggtccgcttg
     9301 atgacattat agaagaatca aaaatgattc tttctggaga acttggaatt gacaaggatg
     9361 gagcagaatt ttctagtttg tttccattta tttgtcgctt ggataacgat aatgaagttg
     9421 atgatcccga catgtgggaa aaagcttgtc caactattaa ttacaatgca gatttaaaac
     9481 ggaaaatgtt tcaagaatac tctcaaatgc aacgtaatgc tggtttaaga cttacgttca
     9541 tgaccaaacg aatgaacaga cctatggaag atacacgatt tgctgttgct tcatatgatg
     9601 atgttctgca tacgaaagaa aaagaatttc ctgaaaaaat ggatgaagtg ataggaacag
     9661 tcgattttgc tgatagacga gattttgcca gcgttgggtt gctaggaaaa tacgataaag
     9721 atgtttattt tacacaacat acttttatcc acgaatcagc ccttcgatta caaaacatca
     9781 aacgagaggt tatagatatt tctatagatc aaggaaaatc acagatcgtt catggaaaaa
     9841 atatagaagc tgattatatt gtaggttggt ttcttgaaat gagtaataaa tattatatta
     9901 aaaaaatcgc tatggatatg taccgtgcaa aaatattgaa gcccgcttta gaagaagcag
     9961 gttttactgt ggaaattgtt cgaagcggat ctgttacaca tggtatgtta aaagatctgg
    10021 ttgatgacct ttttattaat caacgtttat tttttggtga cgatgcgatt atgcgttggt
    10081 attgcatgaa tgtatatgaa gagcatattt ctaatggaaa tatacgctat gaaaaaatag
    10141 aacctgaaac tagaaaaacg gatggctttt tttcattcct tcatggtttg aattttttag
    10201 atgatattta tgattctgct cctgtaacag tcacaaatag ctcagtagaa aatacaggaa
    10261 ctggatttac tcctctagta ttctaacttg aaaggaggtg agaaagtggg gatttttcaa
    10321 aaggcggtag gatacttcac aaaaaaagca acggttcctt tagaagaata cttttgtaaa
    10381 ttgcaagttg attttgtgta tcgaaaattt gcgattgaaa cttgtattga tttgattgca
    10441 aatgcgatga gtaaagcgga attcaagtca tatgaagatg gaaaaaataa aaagaatgat
    10501 ctttactata ggctgaatgt agctcctaat aagaaaaata atgcaacaga atttagaaaa
    10561 aaactgatca ggagattaat attctacaat gaagtattga tcgtttctcc gtctaataat
    10621 tctagcgaaa tatttattgc ggatagttgg gatgtcacag aatatgcatt gaaagatgat
    10681 gtgttttctc aagtgcaaat taacaacata gtccttgata gagaatttct agaaagtgat
    10741 gttatctata taaaatacgc agatcaacaa attaggcaac tagtcgatgc gtattatcaa
    10801 gcgtatggga aactcatttc tagtgccatg aatgtttaca agcgctctaa cgctcgtaga
    10861 tacgtactga aagggaattt attccgaccg caagacaata caacacaaga tcaaatcaat
    10921 aaaatgatga catcacaatt taaggctttt atggaagctg ataatgcagg tgcggtattt
    10981 caattacaaa atgagtacac attagaagat ttcagcggaa acttccaaag caattcaaga
    11041 gatataaaaa acttaataga cgacatcttt gagatgacag cagcagcgtt tcacgttccg
    11101 aaaaacctac taaagggaga catgagtggg ttatcggatc aagtggacgc ttttttaatg
    11161 ttcgaaatca taccgattgc tgaacttatt caggatgcgt ttaacgctag tctctatgaa
    11221 gtagaagaat acttgtcagg gaattttgta cgtgtggata caactatgat caagattact
    11281 agcttcaaag atttggttga cgctattgat gtaggcatta gaaatggagt atttacaatc
    11341 aacgaaggaa gagagcgcgt tggaaatgat cgctctgata aggcgatggc agatgaaata
    11401 tttataacta aaaacaatca acaagtatcg aaaggaggtg aggcgaatga cgacaatgaa
    11461 aacatttcta gcagtaaaga atgaaggcgc agtaccgcaa atttttattc agggatttat
    11521 tggttctagt tggttctttg aagggaatac tgacaaggga atcaaaaata ttttggatag
    11581 tctaggtgat caagaagaaa ttgaagtagt aattaattca aacggtggag acgtatttca
    11641 agggattgct attgggaact tacttaagtc aaataaagca aaagttaacg ttgtgattaa
    11701 cggcttagcc gctagtgctg cttcaattat cgcaatggct ggcgatacta taaaaatcta
    11761 caacaatgca caattgatga ttcaccgcgc ttccacatac ggagaaggaa atgtcgatga
    11821 cttccgtacg attgctgacc aactggaatc aattgataaa tcggtaaagg cttcatataa
    11881 aacacgattc aatggcacag atgaagcatt gcaagaactt cttgaaaaag aatcgtttat
    11941 ggatgcagaa acagctttga gttatggatt ggtcgatgaa attatcgatg cagaaaatag
    12001 ctcaggtact gaagctaaaa aagaacaaag cgttgaagaa attttgaatg acgttaaaga
    12061 aaaaagagca gaaaaaattg ctgcatttac agcagcatta aataaaacat ttggacaagg
    12121 agatgtaaaa taatgacagt taaaaattta aaaggtgtaa cagctgcaag cgaccaattg
    12181 atgaaagctt ttaaagatgg taacgaagaa tcttttagcg cagctatggt aagcttatct
    12241 aaggaaattc aggataaaat tttagaagaa gcaacagcaa aaaatcaaga tcaattagta
    12301 ttaatgaacc gtggtcagcg tgtattaact acacaagaaa caaaattcta taacgaagta
    12361 gtgaaaaacg aaggttttgc aggggtcgaa gaattagtgc cagctactgt atttgaacgt
    12421 gtatttgaag atttagaaca atctcatcca ctattgcaaa aaattacttt tgttaacaca
    12481 actggtgtaa cagaatggat tgtgtcacgt ggagtcaatc cagcatggtg gggtaaactt
    12541 tgcgaagctg ttaaaaaagt tttagataat ggctttgatg taattaacat gaagcagttc
    12601 aagctatcag gttatattcc tgtatgtaag gcaatgcttg atttaggtcc agtatggtta
    12661 gatcgttatg tccgtactgt tttagtagaa tcattgagaa ttgcattaga acaagcaatt
    12721 gttgatggta ctggtaaaga tatgccagtc ggaatgatgc gtgacatgag caaacaaact
    12781 agcggagaat atgctgaaaa aaaagcagaa cctattacag ctttagatgc tgtaactatg
    12841 ggcggtttga tggcgcgact atcaaaattc aatatcgaag gtgtgaatga tccgatttat
    12901 cgtaatgtga atccttctga tgtggtccta attgtgaatc caactgatta ctggtctaaa
    12961 gtattcccag ctaagactgt actaactgct aatggagaat acgtacaagt attgccagta
    13021 ccagtttcag atttgcagtc aacggctgtg ccagaaggaa aagcagttat tggggtagcc
    13081 tcagattact tcatgggtgt aggatctaca ctaaaaattg aagcttcaga tgaataccat
    13141 tttgttgaag acgaacgcat ttatctagct aaacaatatg caaacggtca acctaaacgt
    13201 aacgatagtt tcattgtatt agatattagc gctttgggaa ctactactac aactacaaaa
    13261 ccaacaacca caacaactac aacacaagcg taggtgatca gaatgaagta tattctttgt
    13321 cagccggcaa tcaatcggtt taaatgggag cttgaagttt gtttaactaa tctgaagaaa
    13381 ctaggaatca aagatatcgt attgcttttc agcagacacg atgatcagat tcctattttt
    13441 tttgagaagg aatatggtgt tgaagttcat gtgtacgatg atctgcggga cgacaaagag
    13501 tatattcctt cgattaaacc atatttatgg tggaaatatt tagaagaaga tcattcgcgt
    13561 gaggacgacc gatatttcta tatcgattcg gatgtcattt tcaataaaag aattaatttg
    13621 cgcaaattgc cttctaaaga tgatgtttgg tattgtagcg actgctgtag ttatctaagt
    13681 cttgattata ttagaagctg tgaaaacgga gaaaatattc taaaagatat ggcaaacatt
    13741 gtaaatgtta cagtagaatc tttggaaact ataaacacta attcaggagg cgcacagtgg
    13801 gttattaacc gccctaaagc gaattattgg aaaaaggttt atctggattc taatcggcta
    13861 tatcgctacc ttagagggca aaaaacaaat ataaaaatct ggacagccga gatgtgggca
    13921 cagctttgga acatgatgta tttcaatatt ggtcctaaag ttcacgagga attagacttt
    13981 tgttttgcta ctgatccaat agaaaaagtt aaagaagtaa aaatcttaca caatgctgga
    14041 gtaacaacaa acgatgaaga tttatttttc aaagggagat acgtgacttc tacgcctttt
    14101 gatgaagatt tatcatttgt aaacaagaaa aaatgctctt acgcatatgt taaagcaatt
    14161 aaggcggtgg ttagatgacg cctgaacaag tgactgaaga attgctaata gctgtgaagg
    14221 ataatattta cgttacctgg aacgaagaag atgagtcaat taaaaagatg atagctaaaa
    14281 atgctgttta tcttcaaagt aaagtgagta caacactttc tttttctcct gaaagcttag
    14341 aatacggatt gctaatcgaa agatgtagat acgactggaa tcgtgcttta gatgagtttg
    14401 aacaaaattt cgctagtgag ttattaggtt tcattcaaca ttatgcgcta caagaatata
    14461 ttgcaggtga tgtgaatggc gaataatcgt agactcgaag aaacattcaa cgatggttgg
    14521 ttaaagattt tgacgcaaac taccaaaaga aatgaactag gaaaaaagat tggtgtagaa
    14581 gatacagaaa tcacttcttt aaaatttaga aatctttcca tgagagatag tgatataaca
    14641 gctatggatg cgatgggatc gaaattaact aagaaagtaa agactccatt tcatccaatc
    14701 gccaagaaat ttaataaaga tcaatatttt atcgtaatcg atagtatgcg ttacaacgtt
    14761 atctatgccg attacgataa tttttatatc tatttttatc ttgaaagtgt gggtgaatat
    14821 ggtgattgat aattctaaag aaaaagaacg tttaaataag caaatttctg ctatcaaaac
    14881 ttccttagaa gagcattttg gcctcaaact ctttcaagac tccgtaggcg aggatgagct
    14941 acctgatgat tttaattact tcattctcga aacaggagaa atagaaatga tcactgagcc
    15001 aaaatatagc gtgggtcaaa atctatatct aactttctat tcagaaaata gagaagattt
    15061 aacaggagat tcactagata ttatttcatt gattcaaaat cgttcgattc gttttcagag
    15121 aatggatccc aatcatttaa aactagagaa ccaagatcgc tatatcgatc aattggtatt
    15181 tacgtttaga cgattattga agagtgattg tcatggctaa aaatagttgg gagctaaaaa
    15241 taaatggaca tgatgaactt cttgtgcgga tggaacgcta ttcaagcgag agcgaacgac
    15301 tgattaacga agcattgaaa tcaaaaggtt cggctattgc agtggatagg attacagaaa
    15361 aaattcctgt ttctgaagca gatttaagaa gagggcacca acacgcaaaa aatagtcgtc
    15421 cacttaagac tcaatacatt aatttgggtt tcatcattag acctacaaga aaatttgagt
    15481 atttaaaata tcctgatttg gggataggta cttctaaaag aaatcagccg gacgaattta
    15541 tgagaagagg attaggtctt gcacttgatc caattacaga acttctgatt cgtcaattcg
    15601 ataaattaaa taaataggag gaacaacaat ggctaaaaca acaacagtaa caacttttga
    15661 caatataagt attaaaagaa tttcttttaa ttttaagaat gcaacaaatg caatttcaac
    15721 tgattgtaat ggacaattag atggcgaaac agaaatgcag agaattgtaa aaaaatgcgg
    15781 ttcaacagaa gtaaaatcga aatctaaacc aatcaatatg acggtaacaa ttactgcaca
    15841 tgtaccgatg gaagtttatc gacgcttcaa tgggttgaaa caagatgaac gtattaaatc
    15901 gggaatttac tcttatggtc ctgattccgt aggggaagat ttctctcttg ctgcagagat
    15961 cgtggatgat ttcgaagaaa aaaataagct gattggtatg ttagcatgca cttcgaatac
    16021 aggattaaca ttctctattg aaaatggtgc ggatgaagta gctgcgttag aactagaaac
    16081 aaaagttatg caagatgaat ttggtaaatt ttatcatgaa gcaattgttg cagaacttga
    16141 agaagactta acagatcaat ggatgacgaa tctatctgct gatgtgatta aaaaaacttc
    16201 agttgtgaca actacggcca ctcaatcaca gtaaaaaaaa cggaggtagc gaaatgaacg
    16261 aagattactc aaaaattgaa ctaaacgatg gaacaatttt gaatttagaa cctaaactga
    16321 atatcaagaa attattgatg atcaatagag attttaacac agacgagttt gcaaaaatga
    16381 ctgtgggaaa aggatccatg gatatttctg ttattcaagg tgcaaaggct gtgtatattg
    16441 cttaccgcca agcgaacatg actgattata tttcattcga tgaatttatc gataaatggg
    16501 attttgatat ggctactgcc agctatattt atcaattgat gatgttcaaa caagcacgcg
    16561 atgcttatca aaaagaattt gaaaaagcaa ataaggaaaa aaagcttcaa aagtaaaaat
    16621 gccaaagctc ttagttgaaa cgtgggtcga tgtctattcg atgttgaccg acgttttttc
    16681 tatgccttca gatttggttt taagcgatat ctgtttagat gacattttgc aaatggctta
    16741 caacaagagt gcttatgaag gatggaaaaa ctatgcaata aaccaatccc agaaaaacta
    16801 aagaaaggag gtaaaaaatg gctaaaaaga gaacagaagc agaagtaaca ttcatagcta
    16861 acgatgacgg attgaaatct acgttaaaag aaatcagtgc tgaattaact aaaaatagag
    16921 cagaattaaa actagaacaa gctcaattac aacagactgg ttctgaatca gacaagttag
    16981 gaagtaaatt atcttcttta gaaaagcagt atgaattaca aagtcaaaaa gttgaagtaa
    17041 ctagccaacg tttagccaat gccaaaaaat attatggaga aaattccacc gaagttcaga
    17101 aacttgagag agaactgatt aaccaacaaa cagcgcaaca acgtttgtca aacgaaattg
    17161 ataaaacgag taatgcacta gctcaagcaa aaggcgaaat acagacgtac gagtctacaa
    17221 tgcaacagtt ggatagtgaa caaaaaaatg ttcaagctag tgcttctctg attgaatccg
    17281 aatacaaaaa atggcaagca actgctggtc aatcagcttc tgaatccgag aaattagcga
    17341 aagcccaaga atatgtttct caacaatctg aaaatgcaga gaaaacgata gatatcctga
    17401 gacgacagtt agaagctaca cagtctgagt ttggcgctac atccacagaa gcaatgcaga
    17461 tggaggcgaa gcttaatgat gctgaacgtg aatttgaaga gttaggacaa gctgctaaaa
    17521 atgtagatac aactaacttg gacgatatcg gaagcaaaat agatatgaat aatctaatgg
    17581 aagcttctga cgttttaagc gacattggcg ataagcttac agaattaggg aaacaagcag
    17641 tggactctgc taatagtgta ggtagttccc agagtaaaat acaagctaat tttggtttga
    17701 ctaaacaaga ggctgaagaa ttaacgaatg tagccagaga catttattat aaaggttttg
    17761 gagaatcgtt agatcagtcc acagatgcat tgattttggt aaagcgtaat ttaggcgatt
    17821 taaataatca agatttacaa aatatcacgg aacaagctat ggtcctagaa aacaccatgg
    17881 gcgctgatat ggatgaaacg ttacgtggtg taaatggctt aatggtcaat ttcggcttga
    17941 gcgctcaaga tgcaatggat ttaatggttt cgggtactca aaacggttta gataaaacgc
    18001 acgaattagg cgacaatatg gcagaatata gccaattatg gagtcaaatg ggatattcag
    18061 ctgatgaaac gttcggaatg cttcaaaatg gtttagatgc gggtgcttat aaccttgata
    18121 aagtcaatga cttagttaag gaaatgggaa tatcgttaac agatggtcga tttgagcaaa
    18181 acatggatat gtttagtgaa agtactagaa aagcttttga agagtggaaa aatggcggag
    18241 gaacacaaaa agacgttatt aattccatga ttcaagattt tagcaatatg gatggtcaat
    18301 acgaccaatt aaataaagct tctacaattt ggtctgcact tggcgaagat aacgcgatga
    18361 aagttgtcca atctttgact gatgttaacc atacatttga tgatgttagt ggatctgcac
    18421 aaaaaatgaa tgaagattct actactccgt tacaagaatt aaacggaaaa atagctgaat
    18481 taaaggattc attagctcct ataggcaaca caatcataga tgcactcgaa ccagtaattg
    18541 attttctagg aaagatggct gatgcgttta ataatcttcc acaaccagta caggattatg
    18601 ccgtagcgat tggcggattg actgctgcat ttactttatt aatgccaata atagttggct
    18661 tcatggctct aggtggtcct actacattaa taataggagc agttattact gttattgctg
    18721 gagttatagc aattataaaa aactggggcg caattactga ctggtttaag ggaatatgga
    18781 gtaaattcac tgattggttg ggtggtactt gggaaagtat aaaagaaggt gcctcatcag
    18841 tttgggatgg agttaaagaa acctggtctg gatttgtaga ttgggttcaa gatatttggc
    18901 aaggagtttc tgattggttt ggagagctat ggagcggatt agttgaagga gcttccaaca
    18961 tctggcaagg agtccaagag acttggcaag cattcgttga ttgggtttca aatatttgga
    19021 acggagtcaa agaagtatgg tcgattattt gggcagacat tgtaggaatt gttcaaatac
    19081 catggacctt aataacgtca ttgattcaag ccggtattaa tattatcgtg ggtatttttg
    19141 atgtagctgg acagttatta ggcgcagctt ggcaagctgt ttggacacct atttctgatt
    19201 tccttaaaaa cacttgggat actatgacac aatgggtaag catcgcttgg aatggaattg
    19261 taactacatt ccatactata tttgatccag tagtggcatg gtggaatggt atatggacag
    19321 ctattagtac tacggcttca aatatttgga attcaattag tgcaacagct tctagtattt
    19381 ggaacagtat caagaataca atcactagct tggtacaagc agctgctaca gtaattcaaa
    19441 atatttggtc aactgtatct agttggttag gtggaatttg gaattcaatc agctctacag
    19501 catcaaatat ctggaatagc gtgactagta gtataagcaa tgctataaac gcagctaaaa
    19561 gtgccattca aagtgtttgg aatagtatat cttcgtggat cagcggaatt tggaacggta
    19621 tcaaaaacac tgctttgaat ctttggaatg gaattacaag cactattagc tctaaagtaa
    19681 acgatggaaa aaatgcaatt tcaagcggtt ggtccaatct aacaggtatt gtttccgaca
    19741 tattcaataa tgttaaaagt acaattgcta acatttggga aggtatcaaa aagactgtta
    19801 gcgctccaat tgattggatc agagataaaa tcagtagtat ctttgataat ttgaatattt
    19861 ctataccaca tattccgtta ccacatttta aattgagcgg agaattcaat ccattgaagg
    19921 ggaaaatccc aacgttgggt gttgattggt atgcgaaagg tagtgtgttt aattctccga
    19981 atattatcgg tgtcggcgaa gcaggacctg aagcagtttt acctttgaaa agatctgtgc
    20041 tgcaagaaat tggtgatcgt atcttgagta gcacatcagt ttcatctagg gcacaaacga
    20101 ttcaacctgt gaataactac gaattcaatt tcacaattga tggtaacgca gatgaggtta
    20161 ctatgaagca aacaactcaa caaatcattg atagcattac aaaagttcaa aatgataatg
    20221 cttcggcatg gcgttaaaca ggagagtatt tctcctgttt ttttagtatt aaaaaggatg
    20281 tgaaaaaatg actgattgta tacattctat aatcgatgga tttcctgatt atttgcataa
    20341 attggcttta gctgaaagac caaccatacc ttctccaaaa agacagagag ttgaaacttc
    20401 tgttttagga aggttaggtg gcttagtaca agattactcg tttgaagaca tgtcgtttac
    20461 attgcactat aactatttag aggatgtgga agaccatcaa gcgttcaagc aatcgtttta
    20521 tatcatgcgt cattggttaa attatgcaaa gaaattagaa ttctctgatg atcccaacgt
    20581 ctattatgtt atccagacta tcgatattgg ggatgcagaa aacgatattg ttgaatgggg
    20641 agagttcgat gtaaatatta ctgcgaaacc attcgcaaga gttcaagaag atgtacctat
    20701 aaccgtagat aaaccacagt catttaactt gctgaataat agtttagaag aaagttttcc
    20761 aaagattatc atcactcctt cagctacttc atgccagttc atcttaaatg attatgtgtt
    20821 tagttttgaa ggcttagtag taggaactga tgtagtcatt gatagtgatt taatgctttg
    20881 ctacgaagag caatcggacg gagatatttt agatcgatcc aacaaaatga agaccatgca
    20941 atatccgaca ttgcaagtgg atattaatta ttttaattgt actggtttga gcaaaataca
    21001 aatttatcgt aatgggttaa ggtaggtgaa atagatgatc gataatttaa taactattta
    21061 cgataaaaat gacgcgaata atttagctga acatttatat gatacacaag gtttaggcgc
    21121 tttgtcagac tggttaacag ccactgttag caataaatta aacggagccg agatatttca
    21181 gggtacttat ccaataagcg gaactaatgc agacttgatt atagaaggac gtattattca
    21241 gtgctatgtg gatgaaaatc gagcaaagca acgtttacgg atttattatg caaagacttc
    21301 tgtaatagga aatatgatag aagtaaaagc tgaacctatt ttcaatgata taagaaaatc
    21361 ggtgttgaat aaatatgaca gcggaacaga aaagatcact gctactcagg catggcaaaa
    21421 cgcaaaagtt ttagcaaaac cagctattcc ttcgcagttt tctttctcat cgttagtaga
    21481 tacgcttgct aatgtgaaga tagaaaaggc gaatttttta gaattctttg gcggaaagga
    21541 aggatctatc ctagatcgat ttcatgggga atttcttaaa gataataaca cattacgtca
    21601 tgaaacaagg ctaggtacgg atcataaaat caaagcgatt tatactaaaa acttaactgg
    21661 tctcgactta gagatagatg ctcaaagtgt tttagttgga gtttatccat tcattagcag
    21721 ttcgtcagaa ggagaggatg agatcactct accagaagaa gtcattttca cggattacgt
    21781 ggaagattat cctgctggat atgtttcttt tgttgatttt aaagacaaag cgactgatgt
    21841 ggccacatta agggaagctg ctaaagactg gttgaaaaca aacatagata aacagaaacc
    21901 acaagtgagt ggttcgattg aattagtacc attgaggcat caaagaggct atgaaaaatt
    21961 tgttgatcta gaaaaagttt cgatgggtga cggagtagat gtgtatcatc cacagttaaa
    22021 agtgaatatg tcagcaagaa ttgtggaata tacgtttaat gttttaacca attcatacga
    22081 taaattagtt gtaggaaacg tcaaaacaaa cttcttagaa aatacagaga ataatgtcaa
    22141 caatttgatt aatgatgcca ttgatcaatt gaaaaatggt ggcgaaatca gtgatttaat
    22201 caatgatatt gtagatcatc aaactgacat gattactggt caaaatggtg gttatgtttt
    22261 attagatcct aaagaagcgc ctagtcgtat tttgattatg gacacaccag ataagaatac
    22321 cgcaaggaat gttttacaaa tcaacaatgc tggtattggt ttttctaaaa ctggcattaa
    22381 tggaacatat gaaacggcat ggacgttaga tggcggattc aatgcctcgt ttattacggc
    22441 tggtgaaata gtaggaatta ctattagagg tactacatta attagtgatg gtgctgatta
    22501 tagaacaagt attgctaatg gcaaaatgac ttggtactca aaaaaagtta acaaagatat
    22561 tatggagcta gaagcacgtg attatgtaag tgctgatgcc ggtattgtat catacaccat
    22621 gaaaactggt ggtggtttca tgattagaaa tccacagggt aacttggttt ttagtacgtg
    22681 ggataatggt aataacagac cgtttctatc ttttggtgcg cccaatttca ggtatagcaa
    22741 tgctagttat gtaacttctg gcgacggtag ttctttaagc attaatggta gtgcgggtaa
    22801 ctcatgggaa tttaaggtag ctggtaggac tatgaaattt actagtgatg gtatgctaac
    22861 gttaccaggt tgtttttttg gttcatggga agatgggaaa cttgctaggt ttgaacaatc
    22921 aacggtacaa gtatataaag attttactgt tagaggtact aaaaactcaa ctgtaccaac
    22981 agaacattat ggacaacgac tattgaacgc ttatgaaact ccagaatatt atttcgctga
    23041 ttatggggaa gccgttacag gtgacgatgg taaagttcgt gttgatattg accccatgtt
    23101 tgctgaaaca gtaaatctaa gtcggtatat gacacatgtg acacctacag aactagtttt
    23161 gtgtgctgtt actcatgaag atattgacca tttcatcatt gaaactagta agccaaacgt
    23221 attagttaga tggaatttag tggcacaccg tctagggtat gaagatatta gattaaaaga
    23281 ggatacagca tatgatagca cagtgcttga ccaaaaacgt ttttaaaacg aagacaagga
    23341 ggtatataaa tggctagcag tttatataat ttggctttag atttcagcaa agaattaaac
    23401 tacaccaaag ctattatggc tcgtcaaggt gataaaggga ttacggtgac ggttaaaccg
    23461 tttctaaatg gcttgcagat ggatacgagt ggcggaacat ttactttaaa aggaacaaca
    23521 ccatctaacc gttacgtaga taatgttgca actagtgtaa ctagtgaaga agtcacgttt
    23581 tctcttgatg gcacatttat gagtgaagca ggatattata aacactgcta cgtagaatat
    23641 agaaaagaca atcaaatttt aacaacgcaa gatatcattt ttttctcact aggagtgtct
    23701 gacatttcgc aaggccaagc cgatgaatat gtttcgcaat tagaagagtt gattcgaaag
    23761 tacaacgaaa cttttgatgc ttttatggct gaaatcaaag gtagagtgga tagcttaaat
    23821 caacagatta ctgatttaac tggtcaagct aaaacgctac aagacaagtt agatgctctg
    23881 aaagaagaaa tttctaagtt aggtaactta caagtgatgt acagtaacag catcgacttc
    23941 ggggactatg attatagtgg aaatcctaat ttgttaagta agctatcata cgacttaatt
    24001 gaaaatcaaa atacttcagc tggaacactt tctaaaggtg aaaactcgtt taaatataat
    24061 aagatatcag ctgaagtgga aggtggagta gagctatatt ataaacgaag aggtatagct
    24121 aactggctac c
//
LOCUS       DBBGRF010000044        24034 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000044 DBBGRF010000000
VERSION     DBBGRF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.044"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(129..585)
                     /locus_tag="ACIZD4_002020"
                     /pseudo
     CDS             complement(129..585)
                     /locus_tag="ACIZD4_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            750..3112
                     /locus_tag="ACIZD4_002021"
                     /pseudo
     CDS             750..3112
                     /locus_tag="ACIZD4_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
     gene            3480..4403
                     /gene="truB"
                     /locus_tag="ACIZD4_002022"
     CDS             3480..4403
                     /gene="truB"
                     /locus_tag="ACIZD4_002022"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGC5990930.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4407..5348
                     /gene="ribF"
                     /locus_tag="ACIZD4_002023"
     CDS             4407..5348
                     /gene="ribF"
                     /locus_tag="ACIZD4_002023"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HGC5990931.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5700..6485
                     /locus_tag="ACIZD4_002024"
     CDS             5700..6485
                     /locus_tag="ACIZD4_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC5990932.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6498..7349
                     /locus_tag="ACIZD4_002025"
     CDS             6498..7349
                     /locus_tag="ACIZD4_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HGC5990933.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7473..7925)
                     /locus_tag="ACIZD4_002026"
     CDS             complement(7473..7925)
                     /locus_tag="ACIZD4_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990934.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8390..8758)
                     /locus_tag="ACIZD4_002027"
     CDS             complement(8390..8758)
                     /locus_tag="ACIZD4_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HGC5990935.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8908..9390
                     /locus_tag="ACIZD4_002028"
     CDS             8908..9390
                     /locus_tag="ACIZD4_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HGC5990936.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9427..10437
                     /locus_tag="ACIZD4_002029"
     CDS             9427..10437
                     /locus_tag="ACIZD4_002029"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGC5990937.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(10552..11265)
                     /locus_tag="ACIZD4_002030"
     CDS             complement(10552..11265)
                     /locus_tag="ACIZD4_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990938.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(11438..12045)
                     /locus_tag="ACIZD4_002031"
                     /pseudo
     CDS             complement(11438..12045)
                     /locus_tag="ACIZD4_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            12529..12756
                     /locus_tag="ACIZD4_002032"
     CDS             12529..12756
                     /locus_tag="ACIZD4_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HGC5990939.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            12772..13937
                     /gene="hemW"
                     /locus_tag="ACIZD4_002033"
                     /pseudo
     CDS             12772..13937
                     /gene="hemW"
                     /locus_tag="ACIZD4_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
     gene            14171..15214
                     /gene="hrcA"
                     /locus_tag="ACIZD4_002034"
     CDS             14171..15214
                     /gene="hrcA"
                     /locus_tag="ACIZD4_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGC5990940.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            15308..15871
                     /gene="grpE"
                     /locus_tag="ACIZD4_002035"
     CDS             15308..15871
                     /gene="grpE"
                     /locus_tag="ACIZD4_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGC5990941.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            15922..17751
                     /gene="dnaK"
                     /locus_tag="ACIZD4_002036"
     CDS             15922..17751
                     /gene="dnaK"
                     /locus_tag="ACIZD4_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGC5990942.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            17902..19068
                     /gene="dnaJ"
                     /locus_tag="ACIZD4_002037"
     CDS             17902..19068
                     /gene="dnaJ"
                     /locus_tag="ACIZD4_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGC5990943.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(19150..19779)
                     /locus_tag="ACIZD4_002038"
     CDS             complement(19150..19779)
                     /locus_tag="ACIZD4_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990944.1"
                     /translation="MGQLSDNQQLCQERINPLLELLERVFSYYGQALLTVHRQQIIIL
                     VNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSFLHAKQVCEWIAF
                     HQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLFKKTLACFSKNNG
                     SIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLLVQT"
     gene            19791..19964
                     /locus_tag="ACIZD4_002039"
     CDS             19791..19964
                     /locus_tag="ACIZD4_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990945.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(20192..20398)
                     /locus_tag="ACIZD4_002040"
     CDS             complement(20192..20398)
                     /locus_tag="ACIZD4_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990946.1"
                     /translation="MICKASSGDEMAVKEILKFYDGYISKLCLRPFYHSESGKIIMQV
                     DEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(20424..20843)
                     /locus_tag="ACIZD4_002041"
     CDS             complement(20424..20843)
                     /locus_tag="ACIZD4_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HGC5990947.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            21347..21700
                     /locus_tag="ACIZD4_002042"
     CDS             21347..21700
                     /locus_tag="ACIZD4_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990948.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            complement(21760..21927)
                     /locus_tag="ACIZD4_002043"
     CDS             complement(21760..21927)
                     /locus_tag="ACIZD4_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HGC5990949.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(22046..23965)
                     /gene="tet(M)"
                     /locus_tag="ACIZD4_002044"
     CDS             complement(22046..23965)
                     /gene="tet(M)"
                     /locus_tag="ACIZD4_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HGC5990950.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT         8014 a         4168 c         4823 g         7029 t
ORIGIN      
        1 caggggttgc gggatttttt tgttttcatt aagacgtatt acctaagagt tccatgactt
       61 tagtcttgcg gcgtgtcagc taaccaaaaa agagaaaaag aaaagtaaaa aattcgactt
      121 tcttttttct agtagtatat aaatttttgc atatagataa agatcaagat accgataacg
      181 gaagctagat tgtaatctat tttagtgaca gtcaggtata gccaagtaac tagaagatca
      241 gtggaacctg caccataaaa gtttgagttt gtcggtccgt tgacagttaa aagaaaaatc
      301 acgttgaagt tattgatatt tccgattacg ccgcttcgat ttggtcacga tccaaatttt
      361 ggataatccc tgtagaaatt agcatagtag ctgggatacc aattcacata ttgacaaaga
      421 taacagagac ttttacataa aacggatcaa tcaggaaagg aattgctcga tccagcccca
      481 gttttccagc aatgtgttaa ctggcccagc gtcattcagc aaattatgca tgatgaggag
      541 cgaaatgaac tgcggaacag ccattgtgat aacgacaagt tttttggatc aatgtaaaaa
      601 acgtcagcga aaggaaaaat ttcgtggttt tttatacctg ttcatttggc tagatataaa
      661 atccaaacaa atgaacagaa gtgcttatta ggtttcaatt gggagtatct gcgctagaat
      721 aagagtaata atgaaaagga gtgttatgta tggattattc tagtaaagaa tactttgata
      781 aaatgacggc ttggtggcgt gctgctaatt atctttctgt tgggcaactt tatcttaaag
      841 ataacccctt actgagacgt acactgaaac ccgaagatgt caaaaaacat ccaatcggtc
      901 attggggaac gattcctggc caaaatttta tttatgtcca tttgaaccga gtcatcaata
      961 aatatgattt gaacatgttt tatattgaag ggccaggaca cggcggacaa gtcatggtat
     1021 cgaatgctta tttagatgga agttacacag agatctatcc agaagtaacg gaagatgaga
     1081 caggaatgca aaaattattc aaacgatttt catttcctgg aggcattgct tctcatgcag
     1141 caccagaaac accaggttct atccatgaag gcggagagct tggatactct ctttcacatg
     1201 cagtcggagc tgtattagac aatcctgaag taatctctgc tgtcgtgatt ggtgatggtg
     1261 aagcagaaac cggtccttta gctggaagct ggttctcaaa tgtctttatc aatccagtga
     1321 tagatggagc tgttttaccg atccttcatt taaatggtgc aaaaatagcc aacccaacga
     1381 tcttggcacg taaatcagat ggagaattag caaattactt taacggactt ggctgggaac
     1441 ctttctttat tgaaggaaat gattcagaaa aattaaatcc tgttatggct gaaaaaatgg
     1501 atcaagcaat cgagaaaatt aaatccatcc aaaaagaagc tcgcctgaag acagcaacag
     1561 atgtcgtgat gccaaaatgg ccagtattga tcgtacgcac accaaaagga tggaccggtc
     1621 caaaagaatg ggacggggaa ccaattgaag gaaccttccg agcacaccaa gtaccgattc
     1681 ctgtagatca agaacatatg gatcatgcag atgctttact ccgttggctg aaatcctatg
     1741 aaccagaaaa attatttgat gcacaaggac gtattttaga agaaatcaga gaaatcgcgc
     1801 ctactggtga ccaaagaatg gcaaaaaatc ctatcaccaa tggtggaatc gatccaagac
     1861 cgcttattat gccagattgg aaaaaatata ctttgcaatt tgaaaaacca ggctccgtta
     1921 aagcagaaga tatgaccgaa cttggtaaat tcgttcgcga gatcattgag aaaaatccag
     1981 aaaatttccg tatatttgga ccagatgaaa caaaatcaaa ccgattgaat caagttttca
     2041 aaacgacaaa tcgccaatgg atggaaaaaa tcgaaccaga aaatgatgaa tggctttcgc
     2101 catctggtcg cgtcatcgac agtcaattat cggaacacca agatgaaggg ttcttagaag
     2161 ggtacgttct gactggacgg catggttttt tgcaagttac gaatcattct tgcgagtggt
     2221 tgactctatg ttgactcagc acttcaaatg gatgcggaaa tcacatgacc tttcttggcg
     2281 aaatgattat ccttcgctaa atctcattgc aagctcaaca gtcttccagc aagatcacaa
     2341 tggatatagc caccaagatc caggaatatt gacacatttg gcagaaaaga aggcggagtt
     2401 catccgtgaa tatctgcctg cggatgcaaa tacattgctc gcagtcatgg ataaagcatt
     2461 ccgctcgtca gaaaaaatca atttgatcat ctcttccaaa catccgcgtg ctcaatttta
     2521 ctcagcagaa gaagcagccg tcttagtgaa tgaaggcttg aaaatcattg attgggcttc
     2581 gacagcaaaa gaggaggaac ctgaattggt cattgctgct gcaggaacgg aatctaactt
     2641 agaagcatta gcagctgtaa ctttgctgct ggaagaattc ccaaaactaa aaattcggtt
     2701 catcaatgtc gtagatttat tgaaattacg tcatccaagt caagatccgc gtgggttgag
     2761 cgatgaagaa tttgatcaat attttacaaa agacaaaccg atcttatttg ctttccacgg
     2821 ttatgaaaca ttggtccgca cgattttctt tgatcgtcat aaccatcatt taatgattca
     2881 tggctacaaa gaaaatggag atatcacgac accatttgac atgcgtgtag taaatgaact
     2941 tgatcgttat catttggcaa aagacgcagc tttaaaaatc aaaggaagtc aagcagaaga
     3001 ttttgcgaaa aaaatggatc agaaattaca agaacatcaa aactatattc gtgaaaatgg
     3061 tattgatctg ccagaagtat tggattggaa atggaaaaat cttgaccaat aaaatgataa
     3121 aatcgatccc gcaaaataga attttttaca ttgattaaga aactgaaaaa ataaataaaa
     3181 aaaacggaaa aaagactgga agaatggcca gtcttttttt tcgtttttgg gaagtgaaaa
     3241 ccaaactatt tacctgtaag ccacccataa atccaatcaa atggtgcaaa gaaaaaatct
     3301 tccattctat tccctccttt aaaaaagcat aacatgattt ctatttacgt gagcatgaat
     3361 tttgttacgt ttttattgcc gaaaaataaa aaccgttcat tatgatgtca aattcgtcag
     3421 taattgatgc aatgtgttat aataattcag ttaaatcaaa aatgaaatgg agaaaagaca
     3481 tggacgggtt attaccttta tggaaagaac gcggaatgac aagtcatgat tgcgtattca
     3541 aattaagaaa aatcttacat acgaaaaaaa tcggacatgg gggtacgctt gacccagacg
     3601 tagacggtgt gttgcccatt tgtattggaa aagccacaaa agttatcgaa tatttgacag
     3661 attctgggaa aatctatgta ggcgagataa ctctaggttt cagtacaacg acggaagatc
     3721 gatccggaga acgggtagaa acaaaaccag tagatatgtc tttatctgaa aaaaaaatag
     3781 atgaagtgat ggcttcattt attggtgaga tcacccagat accaccaatg tactcagcgg
     3841 taaaagtcaa cggtaagcgg ttatatgaat atgcccgcaa taatgaaaca gtggagcgtc
     3901 ctgttagaaa ggctcagatt taccgtttta tccggacaag tgaattgaca agagacgaag
     3961 tgacaggaac catttcttgg cgcttcgaag tagaatgcgg gaaaggaacc tatgtccgca
     4021 cattagctgt agatacaggc aagaaacttg gttaccctgc gcacatgtct gatctgaccc
     4081 gaacagcaag tgccggtatg tcccagaagg atgctctgac attagaagaa gtagctcaag
     4141 ctgtgaaaaa tgggacaatc gatgattgtt tgctgccaat agaaaaagga gtggaacggt
     4201 tcaaacgagt agatattact gatgaagtat ggcagaaagt aaaaaacggt atgagacttg
     4261 attatactgt atttgcgctc ccagaaatgc cgtcagaaga aattgctttg ttttataaag
     4321 gaaaagttgt cagtatttat cagccaaacc cgaaagaaaa aaacaaatta aaacctagta
     4381 aagtattgag aaatgaggaa taacgaatga atatcatcaa gatcagacat ccttaccaat
     4441 cagaacaaat tccagaagac gatgtcgttt tagtgctggg atttttcgac ggcgtgcata
     4501 tcggacacca gaaagtcata aagacaggta tggaaattgc acaaaaagaa ggattgaaat
     4561 tagcattgat gactttcaat cagcatccat ctattgtctt taaaaagatc gatcctagca
     4621 gcgtgaaata tttgactagc cttaagcaaa aagaagaaaa aatggccgct ttgggtatag
     4681 attatttata tgaagttgat tttacttctt cttttgctca tttagcaccg caggaatttg
     4741 ttgatcaata catcgtaggg ttacatgcaa aatatgctgt ttccggtttt gattatacgt
     4801 atggaccaaa agacattgca gatgtcgctc attttcctga atatgccaaa ggaagattca
     4861 aaatcgtcac agtttctaaa gaagaagaac aaggtgaaaa aatcagctct acccgtattc
     4921 gtggattact agacagcgga caagtaaaag aagcagcaaa actattaggt tgcacatatg
     4981 aggtagaagg ggtagttgtc catggcgatg cacgaggcag actactagga ttccctacag
     5041 caaatgtcaa agtaaagagc acggttcatt tgcctaaaga aggtgtttat gtgtcggaaa
     5101 taaaaattgg ggaaacatgg tatccagcca tgggttcaat tggacataat gatacattcg
     5161 gtgaaggacg ggagctgact gtagagttgt atattttgga ctttaatcaa gatatctatg
     5221 gtgaacatgt cgcggtacgc tggaatcaat ttttaagaga tcaagtgaaa ttttctagtg
     5281 tagaggaatt gattgaacaa ctcaaggagg atgaacaagc aacagctgaa tatttttctc
     5341 agcaataaaa cattatgcat aaaatctctt gtttatgtat aactagcaat tacaataaaa
     5401 tgggtgataa ataagcccag gaaaggggct gtgacaaaag tcttgtcaca gccttttttt
     5461 ccaaataaat ggtttttcag aagtagcttc ttcggaaata agccgaaatt tcttgaagct
     5521 gaccacttct gtcacaacct ctttctttat agaaataaaa ggacactagc aattcatgaa
     5581 aacgattgct agagcgtatc atttgcttta gactatatat cttggtgtac actcacttta
     5641 aggcggaaat aaaagttatc cgtaataaca ggtttaggta tgaaaaagga gtgggtacta
     5701 tgtacaagga attagaaaac aaagtcgcag tagtaactgg tggctcaaag gggattggaa
     5761 cagcgattgc tcaacgattc gggaaagaaa aaatgaatgt agttgtcaac tataactcgg
     5821 ataaagaagg agcagaaaaa gcagtcaaag caatcgaaga ggcaggcgga aaagcagtct
     5881 ctgtacaagc agatgtcagt tctgaagaag gaatacagcg tttacttgat acggctttag
     5941 aaaattttgg gacactggac gtttgggtta ataatgctgg gatggaaaat cagcatccaa
     6001 cccatgaact tagccttgaa gattgggaaa gagtgttaaa agtcaatttg actggcgttt
     6061 ttatcggaac gaaagcggct ttaaattact ttacagagaa taataaaaaa ggaaatatca
     6121 tcaatatgtc ttctgttcat gaacagatcc catggccaac gtttgctcat tacgctgctt
     6181 caaaaggcgg ggtaaaatta tttaccgaaa cggtagcaat ggagtatgca ccgaagggaa
     6241 tcagaatcaa tagtataggc cctggtgcta tccgtacacc tattaatgcg gcaaaatttg
     6301 atgatcctga acaaaaagaa ctcttggaaa gtatgatccc actaggacgc gtaggtgaac
     6361 caaaagaaat agcggcgaca gctgcatggt tggcttcaga cgaatccagt tatgttacag
     6421 gtattacact atttgcagat ggtgggatga ctttatatcc ttctttccaa ggtggaaaag
     6481 gataagggtg aataaaaatg ggtttattga ttgcattgat cccggcagtt ggctggggga
     6541 tccagccact gattttgaaa aagattggtg gcagaccaac aaatgagata ttaggaactg
     6601 gtattggagc ggtgcttgtc ggcttactcg ttcaattatt cgcttctcca gctggtattt
     6661 cagtgactac atttttgatt agtttacttt ctggtgcatt ttgggttatt ggacaaacag
     6721 gacagtatac atctttcaac ttgattggtg tttctaaaac gatgccaatt tcgactgcat
     6781 tacagttagt cggaacctcg ttgattggtg tcttcgcttt tggagaatgg tctggaagta
     6841 tggggaaaat cattggagca gcagcaatca ttcttcttgt atttggttct gctttaacgg
     6901 caatcagtga tgatcctgga aaaaaaggcg gtatcacaaa aggaattagt ctattagcat
     6961 caacaagtat tggttattgg gtatacagtg cattgcctaa actagttgat gcaagcggac
     7021 tttccatttt ctttccgcaa atgatcggtg tctttttagg ggcagtgatt tatgtgattt
     7081 tccgtaaacc aaccgcattt tctgaagaca agagttggaa agcaacgatc gttggagcca
     7141 tctttagtgt gtcagcattg gcttatattt tttcagcaaa tgaaaatggg gttgctactg
     7201 catatatcat tacacagcta aacgtagtta tctctacatt aggcggtatg tacatcctgc
     7261 atgaaaataa gacaccaaaa gaaaaaaaat taacgattat cggattattg ctgatcgtag
     7321 taggaagcat ggtcacggtc tttatttgag gataaagatg gtaaaatttc atttattaaa
     7381 aaaatatttg tttgaaccaa acagtaagta cttataaaaa aatagcgcta gaatttccaa
     7441 catctctgga atttctagcg ctttttaatt gtttaagata caagggaaat atctgtctgg
     7501 atcaataatt tttcattgat ccattgacta aagtttacga cataattgaa gttaccaccg
     7561 attagtatct ccgcatgatt gtctttataa agatcgtatt gtaaaagacg gtctttttta
     7621 tttgcgtaaa catcgttatg gtactggact aattgttctc ggaattgatt gattgctgta
     7681 aaatcacgat attgaaggtt gaaacgcatc gtgattggtg catttagcat gaatcgctgc
     7741 atttcttttg ctgcttcctc tgcttgatct ccgtatagga actcaaaaag attacgttca
     7801 gaaaatttcc attgcccgcc aacctttgtt ccttttagtt ttccttcatg aagataattt
     7861 ctgatagaac gtgtagtaac acctaattgt tcggctaatt catttactga gtaaaaatct
     7921 ttcaatgttc accctcctat gtgaatggtt ctactgactt agttgatatt tgcttaatca
     7981 cgaaatgtag aaagaacgat tttaattaag gtcattgtaa aaatcaagtc agaaaattct
     8041 aacttttatt tctctaaaga aattcgttct ctcctaaagt gatattatat ttaaatatac
     8101 ctgaaaataa tgggcagtat tatgaaagat cactgatatt ttctcgtatt ttttccttat
     8161 tcaaaagttt tgcaggaaaa ttgctgaaaa aataatttta ctaagtagaa aattcaaagc
     8221 cattcaatca gtgatttttt tcagcacaag aaagactcct tataaaaata gcagatactt
     8281 tgtcaattaa gtgtttaacc agggatgata aaaaggatag gattgaacaa aacctgtata
     8341 aggtgatgaa tagtttcctc gccagtaaaa ggtttattcg tataaagctt tatcgccaaa
     8401 atttatcatg acctttttta tcttcaatat taaatgaaat caattgttca atcaattccc
     8461 agttgattac acttttccaa ggaactttga tgacgttatc cgtatatacg tagcctgctt
     8521 cttggatatt tttttcaagg gcacgaatcg ctgctttttc cggtgcgata gaaaaatgat
     8581 ttttagcaaa actaaatgca ataataaagg taccatggtc agtaaacata ggttggttcc
     8641 attttacagt tgtgtctagc tggggatacg tttctgttat cttagcaaaa aggtctttga
     8701 tcttttgttg atgttctttt tctttgattt gattgatgat cggctgaaat ttttccattc
     8761 taaaacgcct ccattaagtg gtttgattta ttttaccaga aaaacaatag ttatgtataa
     8821 aaaacgaaca aaacacaagt aatgttgtaa ccgctatatt tatatgataa gatgtctcaa
     8881 ataataaaat agaaaagaga cataaaaatg attgacttgg caaagaaatt cttacacgaa
     8941 aatatatatt ttgagttgta tcatcatcga gccatttata caaatgaaga tgctttggta
     9001 ataaagaaag aacaaggatt tacaggtaca gagaccaaaa gcttattctt aaaagataaa
     9061 aaagataata actacgtata tctgactttt actacgaaac aaacggattt caaagcatta
     9121 gggaagatcg tcggtaaaag gctttctatt gtttcatcag aacgcatgga agaacaaacg
     9181 ggacaaaagc agggcgctgt ttctccgttt ggttatgaaa aacagattcc gattattatt
     9241 gatgaagagc tcttatcaaa tgaaaaactt gtttttgcac caggtagacc agatcaaacg
     9301 atggtcatcc aaacggttga cttaaacaaa atcatccagc tacttgagat gccgatattt
     9361 ttgatgccgg caaacgaaaa aaacaattaa ccaagtaaaa tagtgcatac ttggaggtga
     9421 agcaacatga taagttatcc attattagaa agaaatgcaa cgattggggt tactgcacca
     9481 tcctcaggcg tatcagagga acaccattcg ttactcgaat cagctttaaa gagaatggaa
     9541 gaaaaatctt tccaagtagt tactggaaag acgctttgga cgcaagataa ggaaaaatca
     9601 ggtccagcaa gaaaacgagc agatgaattc aatcaaatga tgcaagatga aaatatccaa
     9661 atgatctttc cgacttgggg aggagaatta ttgattgaga ttctcgattt tgtcgatttt
     9721 gatgctctac aaccaaaatg gatagtaggt tattcagata ttagtacgtt gctacttgct
     9781 gtcacattaa aaacagggat agccactgca catggaacta accttattga tttaagagga
     9841 gagtacttgg atgaaacgac agcaatgtgg gaaagtgtac tgaaaacaag agaaggagaa
     9901 tcgattctac agcaatcttc tgaaaagtat caaaaagtgt ggccccatga gcattcatca
     9961 tcttctgttt tccatctcac tgaaccaaca aattggcaat cagtcagcgg agatgcagta
    10021 aggatgaagg gacgattatt aggtggttgt attgatacga tcaggcattt aatcggtact
    10081 ccttatggag atgtccaatc ttttaaaaga aagtataatg atggaaagcc gatcttgtgg
    10141 tttctagaaa actgtgagct atcgtcagtt gatttaagaa gatcacttgt tcagatgaaa
    10201 ctggcaggct ggtttgatgg cagctcgggg atcatgttcg gtagaagtgc ggcagaggat
    10261 ttgttagatt ataaaatgaa ggatgtatac gaagatctgt caaaggaatt aaaactaccg
    10321 atcttgtatg atattgattg tggtcatgta ccgccacaac tgacattgat taatggtgcc
    10381 tatgcagaag tagcggtaga agatagaaaa gcgactgttt tgcaaacgtt tatttaaaaa
    10441 attttttcct gccttggagt ctatcaaaga ccaataaatc taaatagaaa agaaagtgaa
    10501 agaagctgac aaaatgctgt cagcttcttt ttgtataaca tattagaaag tctaattatc
    10561 tataactgtc acatcgatta actgtttcac gtcattggga tttcctgtag gaatagctac
    10621 tacagatgca ttatcaatga tttcttgagt tgtttctcta atgaacgctg gataagatgt
    10681 ttgatctgca ggcatttgcc aatgtgaagg aactggataa ctagtgattg tcccgtcatg
    10741 gttacttgaa tacactaaaa ctccctggta actgtatttc ccagtgagca taaccacatc
    10801 tttcggatag actgcactcc ctgcatcata aggggcgata ggtgttcctg caggataatg
    10861 aataacatgt aattcgaaat cacccgatgt atctctaaaa gtattacctc taatagctag
    10921 ccaaacacgt gcgtactcaa tttgtagatc agaatatcct gctaacggat ctattgactg
    10981 agaagactgt gaggaggttg tgtctattgt tgaagaagaa atatttgtct caactgtact
    11041 actagatgta gaagaagtat tgggctctga gactttactg cttgttgaag atgtattcgt
    11101 ttcagtagaa gctgatttct gagtacttga tttttcagct gaactggttt gtctgattga
    11161 acttttgtct gtggtcgcag atggatcact attttcttta ctaggagacg tacatcctac
    11221 aaggaataaa gagaccaaca ataaaataaa acctaacttt ttcatataaa atacctcatt
    11281 atttttttaa taccagtata gcataatcct gaatttttga atccgtaaaa ccttgtctat
    11341 gaatataaat agagtgtatc ttctttgata aatgtcagaa aaagtgtgac aaataatcat
    11401 cagtaaaatt acttgtcaca ctattgataa ggagtattta attgaagaga atgattagga
    11461 gaaaggatct ccgtactttt tatagtaatc atagaatcca agtttgtata gacgaatcgt
    11521 tttttctctt atttcttctg tttcaaaatg gactgcttga agaatcaagt ctgtgaattc
    11581 tataggagct gttccattcg cagtaatcaa attacgatct ttcacagctt gttgttctat
    11641 aaaatcttct ttattctgat aattttccga ttctaaccaa ggaaattgcg catttccggt
    11701 gtgtttgtaa ccttgcaata atccgctctg agctaaataa tcaactgccc cacaaatagc
    11761 agctactggt acgtctgttt ttaacaattt atcgattatt tgatataaat gatgattttt
    11821 tatgtcccat gaattgccac cgatcataat aaaaaggtca actttttcag gtatttgttc
    11881 gattaagtaa tcgatttttg tttttaatcc tccaatggaa gtgacctctg attggataga
    11941 agcagttttg ttttgccatt tctcattttg gtttagtgtg ctagtaatat aagcaccttc
    12001 ccaatcggca tattcctcta atagaaacgt aatcgcagtt ttcattttca agctctcctt
    12061 tactatctat aacaaggaca acagttttaa cctacagaca ttcattaaaa ttgggtagcg
    12121 acagcgaaaa caacaattct taagttttag acagagtata cagatagtca acttaattaa
    12181 atacgaacta aataaaaatg acaggtaatc atttttgttt accagcatta taacattttg
    12241 catacatgga tgacaaaaga accaattccc acttgcttga gtacaatatt aaaagaaact
    12301 ggaaggcaaa aagtaattat agaaacgaaa aataaatcat atcgggcact cagacatgaa
    12361 aacaacccta gagatatata actaggtaac cagtttaatg aaagaaaaaa tcatccaaga
    12421 agtcgattct tggatttttt agtggatttg ttcgccaaat acgtttagta tgcgtatatg
    12481 agaggttgta agcaaagcgt tgtggtctga gcacttaagg aggaatctgt gaaaatagct
    12541 tttcatattt ttgcagattt tgacttaatg ccgaaggtca gctttgcgat taccgtttat
    12601 cgagaggctg taaaagcacc gtgtagctcc gatgacaata agcaagcatt tttagagcta
    12661 ggtttccttg attctaaata tgcggcttat ttcaatgagt tggtgcttga acgcgatttt
    12721 aagaaggtcg aaaacaggca cgacttttcg acgtaaggag aaagaatttc aatgatagaa
    12781 acaataaatc ccgcagaaaa caaggtttct gcgtacattc atatcccatt ttgcgagcat
    12841 atctgctatt actgtgattt taataaagtt tttttagaag ggcagccagt agatgagtat
    12901 gtggaaatgc tgctgaatga aatgaaaata atgctagaaa gtcatccgac agcgaattta
    12961 gaaacacttt acgtaggggg cgggacacca acttctttat ctgctaaaca acttgatcga
    13021 ctgttatcag gtgctagaga gatcctgcct tttcaaaatg gtaatgagtt tactgtagaa
    13081 gcgaatccag gtgatttgac ccgtgaaaaa cttcaagtaa tgaaaaacta tggcgtcaat
    13141 cgtttatcca tgggagtgca gacatttgat aatcgcttat tgaaaaaaat tggacgtaaa
    13201 cacaccgcag aagatgtgta tcaaactatg caatttttag aagcagaaaa ttttaccaat
    13261 gtaagcatcg atttgattta tgcattaccg ggacaaacac tagaaggata tctggatact
    13321 ttggaaaaag ctttggcttt ggatctgcct cactattctt tgtactcatt gatcctcgaa
    13381 aacaaaacaa tgttcatgaa ctgggtacga caaggaagac tcgaactgcc tgatcaggaa
    13441 acggaaacca gaatgtttga agagacgatt gaagcaatgg aaaagcatgg acgtcaccaa
    13501 tatgaaataa gtaactttgg gctctccgga catgaatctc aacataacct catgtactgg
    13561 aacaatgacc actattttgg gtttggagct ggtgctagcg gttatcttgg agatattcgt
    13621 taccgcaaca aaggaccaat ccaacactat ttacgcccat tacgagcaaa tgaacgcccg
    13681 gtattggaag aagaaaaatt gacacgaaaa aatcaaatag aagaagaaat gttcttagga
    13741 ctaagaaaaa aacagggatt actaaaaaac atttctatga tcgctatcaa aaaacaattg
    13801 aatcggtgta cggtgatgtg ctaagggaat tagagcaaga agggttactt gttaatgaag
    13861 aagaccgtgt ttatttgaca ccaagaggga cctttttggg gaacaatgtg tttgagcgct
    13921 ttttgtttga aaaatagttt aaagaatatt tgttttttat ctgaatttaa ataaaaaaag
    13981 ttcaaaaata caataaagga ctattgaaac gttgatataa ctggatttac atcaattatt
    14041 tagaattagc actcttgtgt ttagagtgct aaaaaatgga gtctttctct tgacaggaga
    14101 agggcttctt gctatattta taagtggatt agcacttaga atatatgagt gctaatgaga
    14161 ggtgaggaag atgttaacaa agcgacaaaa cgacatttta cgtctgatca tccaacacta
    14221 tacgagtagt ggcgtgcccg ttggttccaa aacattgatg tctgagggag tcaaggccag
    14281 ctcagcaacg attcgcaatg atatgaaagc attagaagat gaaggattgc tgttgaagac
    14341 tcactcttct tctgggcgga ttccatctgc tttaggctat cgttattacg tggatcattt
    14401 gttaaaacct gctcgcgtag cagaagatga tttgctgctg attcgtcagt ctctaggcag
    14461 agaatttcat gaaatcaatg agattattaa gcaatctgct gagatattat ctgagctgac
    14521 aagctatacg actttttcat tgggacctga aataaaagac cgccgactga ctggctttcg
    14581 tatcgtaccc ttgaataatc gacagattat tgctatcgtc gtaacagata tggggaatgt
    14641 agaaagccaa gtgttcactc ttcccgaata tatgggaagt caggaactag aaaaaatggt
    14701 acagattgta aacgaccgtc tagtcggaga tcctctgatg acggtgtacc ataaacttcg
    14761 tacggagatt ccgatgattc ttcataaata tttccaaacg acagaaggga tgtctcagtt
    14821 atttgacacc gttcttggtc atgtttttga agataaggtt tatgtcagtg gacaaatgaa
    14881 tctcttggat tatgagcccc gtcaagatct tgatcagttc aaatcgatgt tttcttttat
    14941 gaaagactca gacggactta cacaaatgat cactccgatg gatagcaata ttcatatcaa
    15001 gattggtgct gaattaggca atgatttatt gcagaatatg agtatgattc aagcaagtta
    15061 cgagatagat ggtcatggaa gaggtacaat agccttgtta gggcctacta gtatgcctta
    15121 ttctcggatg ttcggtctag tcgatgttta tcgaagagaa ctagcagcta aacttgctga
    15181 ttactaccgt tcgcttgact tgtcaaactc gtaatgtgaa taacgaagct atttgcagct
    15241 gatcgttctc tctttcttag taagagcaat caaacagctg actgaataat gaaaggaaga
    15301 ctgtatcgtg aaagaaaatc aagaagaact agataaagaa atgacagatg ctcagccaga
    15361 accggaaatc gatgtcgaag ctgcagaaga ttcgggtatt tcagaagctg aagcggaaga
    15421 attcgaaaca gcgaaattaa aagctgagtt agaagaaatg gaagataaat acttgcgggc
    15481 tcgtgctgaa atcgcaaata tggcaaatcg aggaaaaaat gagcgtgagc aattacaaaa
    15541 ataccgttca caagatttag ccaaaaaatt acttccatca attgacaacc tggaacgtgc
    15601 attagccaca gaagtgtcag atgatcaagg ggcaggtttg aaaaaaggcg tggaaatggt
    15661 cttggaaagt ttgcgtaacg cactggaaga agaaggaatt gaaaaaatcc ctgctaaagg
    15721 agaagccttt gatcctaatc ttcatcaagc agtacaaact gttccagcga ctgaagatac
    15781 accagccgat acgattgtag aagtactaca agaaggctac aaattacatg atcgcgtgtt
    15841 aagaccaacc atggtcattg ttgcacaata attgtgcgga tataaaactt acactttcaa
    15901 ttaaagaagg agacgttaat tatgagtaaa attatcggta ttgacttagg tacgactaac
    15961 tctgcagtag cagtattgga aggaaacgaa gcaaaaatca tcgctaaccc agaaggaaac
    16021 cgtacaacac cttctgttgt atcattcaaa aatggagaaa tccaagtagg ggaagttgca
    16081 aaacgtcaag ctgtgacaaa cccaaatacg atttcatcaa tcaaacgcca tatcggtgaa
    16141 gcaggttaca aagtagatgt agaaggtaaa tcatatacac cacaagaaat ctcagcaatg
    16201 atccttcaat atatcaaagg attcgcagaa gactatttag gtgaaaaagt cgaaaaagca
    16261 gttatcactg tgccagctta ctttaatgat gcacaacgtc aagcaacaaa agatgctggt
    16321 aagatcgctg gtctagaagt agaacgtatc gtcaatgaac caactgcagc tgctcttgcc
    16381 tatggtttag ataaaacaga tcgcgacgaa aaaatcttag tattcgacct tggtggcggt
    16441 acttttgacg tatctatcct tgaactagga gacggtgtct ttgatgtatt gtcaacagct
    16501 ggcgacaacc atctaggtgg ggacgacttt gataacaaaa tcatcgacta catggtagca
    16561 gaattcaaaa aagaaaacag cattgacttg tctcaagaca aaatggcttt acaacgcttg
    16621 aaagacgctg ctgaaaaagc gaaaaaagat ttatctggcg tatcaagcac acaaatcagc
    16681 ttgccattta tcacagcagg agaatctgga ccattgcatt tggaaatgac attgacacgt
    16741 gcaaaatttg atgaattaac agctgactta gtagaacgta caaaagtacc agtacgtcaa
    16801 gcgctaaaag atgcaggttt atcacaatca gaaatcgacg aagttatttt agtcggtgga
    16861 tctactcgta tccctgcagt tgtagaagca gtacgtaaag aaacaggaaa agaaccaaac
    16921 aaatcagtta accctgatga agtagttgct atgggtgctg ctatccaagg tggcgtgatc
    16981 actggtgatg tgaaagatgt tgttttactt gacgttacac cattgtcatt aggtatcgaa
    17041 acaatgggtg gagtgttcac taaattgatt gaccgcaata caacgattcc aacaagtaaa
    17101 tcacaagtat tctcaactgc ggcagataat caaccagcag tagacatcca tgtattacaa
    17161 ggtgaacgcc caatggctgc tgacaacaaa actctaggaa gattccaatt gacagatatt
    17221 ccagcagctc ctcgtggtat tccacaaatc gaagtaacat tcgatattga taaaaacggg
    17281 attgtaaatg tatctgcgaa agatctaggt acacaaaaag aacaaaaaat cacgatcaaa
    17341 tcttcttcag gtctaacaga cgaagaaatc gaacgtatgg taaaagatgc agaagcaaat
    17401 gcagaagcag ataaagctcg taaagaggaa gttgacctac gtaatgatgt agatgcattg
    17461 ctattctctg tggacaaaac attgaaagaa ttagaaggca aagtggacga agaagaagtg
    17521 aaaaaagcag aaacagctcg cgatgaattg aaagccgctg ttgaagcaaa caacatcgaa
    17581 gaaatgaaaa ctaaacgcga tgcattgaac gaaatcgttc aaaacttgac tgttaaacta
    17641 tacgaacaag cggcacaaca acaagctcaa gaaaacccag aagcagctca aggcggagca
    17701 gatgatgtcg ttgatgctga ttttgaagaa gtcgatggcg acgataaata atcagttcac
    17761 tgaatttcga gagaaggcca aagttgctac tttggctttt tcttttgaaa aatagtttga
    17821 agtatcggtt tttgtttcaa acaaaatatg atatgataac aagcgacgtg aaaatgatga
    17881 gaaccaatag gaggaaagcc tatggcaaca aaacgtgatt attatgaagt cttagggctc
    17941 tcaaaaggag catcagaaga tgaaataaag aaagcttatc gtaagctttc gaaaaaatac
    18001 catcctgaca tcaataaaga acctgatgcg gaagaaaaat tcaaagaagt atcagaagca
    18061 tatgagattt taagtgaccc gcaaaaacgc gctgcatatg accaatacgg gcatgcaggc
    18121 acagatccaa attacggtgc tggtggagct ggtggcggat ttggtggatt cggcggcttc
    18181 tctggtggcg gcttcggtgg ttttgaagat atcttcgact ctttctttgg aggaggcggt
    18241 cggtcagtcg atccaaatgc gcctcgtcaa ggtgctgatt tgcaatatac ggtcgacttg
    18301 tcttttgaag aagcgatttt tggtgtagaa aaagaaatca agtataatcg ggaagaaatc
    18361 tgtcatactt gtggtgggaa cggtgcaaaa ccaggcacac aaccaactac ttgtcataaa
    18421 tgtcatggtg caggtacgat taatgtagaa cgccaaacac cacttggacg agtgatgagc
    18481 cgtcaaactt gtgatgtttg tcatgggaca gggaaagaaa tcaaagaacc ttgtccaacc
    18541 tgtcatggct caggacatga gaagaaagca cattcagtta aagtgaatgt accagctggt
    18601 gtagaagaag gacaacaaat gcgtttagct ggtcaaggag aagctggaga aaacggcgga
    18661 ccatttggtg atttgtatgt ggtcttccgt gtagaagaaa gtgatatctt tgatcgtgaa
    18721 ggttctgaaa tttactatga attgccttta agttttgtac aagcagcttt gggggatgaa
    18781 gtccaagtac caactgtcca tggagatgtg aaattgaaga tccctgctgg aacacagaca
    18841 ggtacgaact tccgtttacg tggaaaaggc gctccgaagt tacgtggtgg tgcaacaggc
    18901 gaccaacatg tcaaagtaaa actgatcaca ccgaaaaatc taaatgaaca acaaagagaa
    18961 gcattacgtg cattcgctga agctggcggc atcaaagttg aagaacagca agaagacggt
    19021 ttcttcgata agtttaaaga tgcttttggc gggaaaaagc ggaagtagtt tttctagtaa
    19081 aaacgctaag tcattaataa ttaaaaacca gacgaacaat catatgttcg cctggttttt
    19141 ttgtagttgt catgtttgta ccaacaaaaa agccagcttt agaatatgat aatcgtcata
    19201 gtttctaggg gtataaccag tgagagaatg gaacttgttc aatcgatatt gcaaggtgtt
    19261 tttatgaata aataattctt ctgagcaatt tttgatgctt ccgttatttt tactgaagca
    19321 tgccaaagtc ttcttgaaca aatgtacttc ttcttctgtc aggcttttca aaatacgttt
    19381 tacatataat gttcgttgat ctgacgggat tgctggtaaa acgatcccga ggtctaaatc
    19441 ttcaaaaaag cggatctcgt tcacagattg atggaaagct atccattcgc aaacttgttt
    19501 ggcatgaagg aaagattgcg gtgtctcttg ctctgtataa caaagcgacc caattccaaa
    19561 gtttagctgt aactgataca ttttattaaa ctttgtctgg attttatcaa gcaatgatag
    19621 caatgaggct ctggaaatcc gattgactag gataatgatt tgttgtctat gtacagtgag
    19681 caaagcctgt ccgtaataag agaagaccct ttcgagcaac tccaataaag gattgatccg
    19741 ttcttgacac aattgctgat tgtcagaaag ttgtcccaca actacataat atggagaaga
    19801 aaaatcaagc tcaattaagt gagggtggta tcgactatgt acttgatatc atcaatgaac
    19861 cgatggtact ttcttatgcg atggaacagg tagagcgatt gcttgtttgt gcaggaaaac
    19921 aagcgatgcg gctgatacga ttaggtgaga aaataagaag ataaaaatac acggtccctt
    19981 catggcgacc gtgcattttt ggtttttatt aaattttata tctaattttc aattatccgc
    20041 ataaacacta tacattcaag cattttgaag tatagaaaaa cactcatctt accacgaatt
    20101 taccacgatt gaatgagcct tgatatgacc gtaaaactac taagggagat aacacgaaac
    20161 tgtgtatctc ccgatttttt tatacagttg attacttcac tccgatttca aatttcaata
    20221 ttgctttcat catgtctgta tgaatttctc cttttagttc ttcatcaacc tgcataatga
    20281 ttttaccact ttcagagtgg taaaaaggac gcaagcataa tttagaaata taaccgtcat
    20341 aaaacttcaa aatctcttta actgccattt catctccgct tgacgctttg caaatcaatt
    20401 caaaagaggg atagccataa tctttacttc ctttcgctca aaagcatttt taacttcctt
    20461 agtcctctag ttcttctact gcaaatagca gaacgtgata catggtacag ttctgaaatt
    20521 tctctgtcgt tcattccttg aaaataacgt aataaaatcg cactacgctg tttttctgat
    20581 agtctatgta aaactgtacc aagtgtttca tcagatacat aaattgtaaa gtgcaagact
    20641 ttaaatgata cacaatcata aaaacaggta tcaatcgttc cacgttcaac ttgtttcgtt
    20701 tcggctattt cacaaaacaa tacttcacgt ttagaatgtc ttgcaagctg tctgtttcga
    20761 cttttcactt tgttcttaat gacaatcagc attaaagaat tgaactgtaa tctgacgata
    20821 tgctcgaaag aagatgtcct cataatctca ccccctttct gtctaggaaa ggaagtgagc
    20881 cttgctcgtt tatctccttt cactcttagt cccaatgtga aagggggatt tgttgcatta
    20941 ctgataaata aactttgtaa aaaagttctg aatagccaaa aaagcatata aacagattta
    21001 tttctctgtt tacatgcttc tgttattcta tctatatgat ttataaaacc acattggtgg
    21061 acgtacttat ctattgcaga tagacgactt tttttgacaa gaacccaatg taaggaaatt
    21121 tattgtatat gatgtacttc atggcgacgt tgacctccaa caaaccgcca tttggaagta
    21181 atatacaata ttttaacagc gtaaatagca ctaccatata acggtttttt ttattggcgt
    21241 ttagtagtgc tttttattaa atataaacct ataaaccata taacacgttt ttctatacct
    21301 gtttttaatt cagtaggaac aataaaatgt atagaggtgg tctactatgc gtaaaaaaga
    21361 agataaatat gattttagag cctttggttt agccattaaa gaagctcgat tgaaacgagg
    21421 tttaactcgt gaacaagtgg gagcattgat tgaaattgac ccacggtact taactaatat
    21481 tgaaaataaa gggcaacacc ccagcataca agttctttat gaccttgtat cgttacttca
    21541 tgtttccgtt gatgaatttt tcttacctgc taataacttg gtaaaaagca cccgacgatt
    21601 acagatagag aaatacatgg atagctttac agacaaagaa ctatccttaa tggaatcttt
    21661 agccagcggt atcaacgaag caagaaacat cgaagactaa ttaaaagaat ccatacataa
    21721 cggaaagagc cgataaaatg agattgtatt aatctcattt tatcggctct gcgtctttgc
    21781 gtctggctct gtaatcacag ttactttgaa ctgctttatt tcaattaaat tttcttgtct
    21841 gcatttcgga caatagaggg ggaatttttt taattcagta tcttccctta tctttaatcg
    21901 tgttttattt ccacatacag gacacaatat ccacttgtag tttataataa ctatctcctc
    21961 ctttacactt taattcaaat ctttattaaa aaatatttca tcttatttaa caagaaacca
    22021 tatttatata acaacataaa atacactaag ttattttatt gaacatatat cgtactttat
    22081 ctatccgact atttggacga cggggctggc aaacaggttc accggtagta acatggtacc
    22141 cttttaactc tgttaaacaa acactacgtc catttgtaaa gaaagttaaa tcactacgat
    22201 attcttgaat acaccgagca gggatttctc cactaagaat gacctcatta tttttcaatt
    22261 gagtgtctac gatgttcgca caatatttag gagcatcgtt gtatgctcgt gaaagatatt
    22321 cctgtggcgc ataaatttta aaactaagat atggctctaa caattctgtt ccagcttttt
    22381 ttaagacttg ttccaataca ataggagcaa gcatccgaaa atctgctggg gtactaacag
    22441 ggctatagta taagccatac ttaaaacaga ttttacagtc cgtcacattc caaccataca
    22501 atccttgttc acagccatag cgtatcccct ccataactgc attttgaaac gattgattta
    22561 agtatccaag agaaaccgag ctctcatact gcattccact tcccaacgga agcggtgata
    22621 cagataaacc aatggaagcc cagaaaggat ttggcggcac ttcgatgtga atggtatatt
    22681 ctgcattttt taacggtctc tccatataaa tgactgtagg ctcttttagt tctatctcca
    22741 catgatactt ttcttgcaac agtgcactaa tcacttccat ttgtactttc cctaagaaag
    22801 aaagtataat ttcatgtgtc gtagaatcca cgtaatatcg tagaagcgga tcactatctg
    22861 agatttccaa aagggcatca agcaacattt ctctctgttc aggtttactc ggttcaacag
    22921 ttgtttgtag tagagggtgc ggattttcaa tcttttttct ctgtggcaat agttttgtat
    22981 ctccaagaac actatttaac ttcaaaaact cattttgcaa aataacaatt tctccagaat
    23041 aagctctatc aatcttacat aattcaccat ttattgaagt atacatttct gtaactttta
    23101 ttttttcttt ttctgatact ctaaccgaat ctcgtaaatg tagtactcca ctataaaggc
    23161 gtatatatgc aagacgttgt cttttttttg tatattcaat tttgaaaaca tttccgcaaa
    23221 gttcagacgg acctcgatgt gttgatgaat aaaatttatt agtaataact tctataaggt
    23281 tatcaatccc tatattactt tttgcacttc catgataaag agggaacaga gaacaattct
    23341 gaaatcttat gctttcctct tgttcgagtt ccaatgcttc taatgattta ccggacatat
    23401 atttctctaa aaggtcatcg tttccctcta ttaccgtatc ccattgttca gattcggtaa
    23461 agttcgtcac acacatatta ggatacagtt ctaccttctg tttgattaca atttcggcag
    23521 aaagtttctc tttaatatcc tgataaaccg ttgataaatc aattccattt tggtcaatct
    23581 tattgataaa aaagattgtg ggaatcccca ttttcctaag tgcatgaaat aatatacgag
    23641 tttgtgcttg tacgccatct tttgcagaaa tcagtagaat tgccccatct aaaactgata
    23701 atgaacgata tacttctgct aagaaatcca tatgtcctgg cgtgtctatg atgttcacct
    23761 tcgtattttc ccactgaaaa gaggttattc ctgtctgaat tgtaattcct ctctgacgtt
    23821 ctaaaagcgt attatccgtc ctcgttgtac ctttgtccac gcttcctaat tctgtaatcg
    23881 ctccactgtt atataataag ctttctgtta aggtagtttt tcctgcatca acatgagcta
    23941 aaactccaat attaataatt ttcatgtgat tttcctccat tcaaaaaccc aaaagggcat
    24001 aaaaatccca gtgataaata cttttatcac tggg
//
LOCUS       DBBGRF010000045        23826 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000045 DBBGRF010000000
VERSION     DBBGRF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.045"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(54..788)
                     /locus_tag="ACIZD4_002045"
     CDS             complement(54..788)
                     /locus_tag="ACIZD4_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGC5990951.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="ACIZD4_002046"
     CDS             1115..1525
                     /locus_tag="ACIZD4_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HGC5990952.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="ACIZD4_002047"
     CDS             1518..2219
                     /locus_tag="ACIZD4_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HGC5990953.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="ACIZD4_002048"
     CDS             2219..3805
                     /locus_tag="ACIZD4_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5990954.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="ACIZD4_002049"
     CDS             3824..4045
                     /locus_tag="ACIZD4_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGC5990955.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="ACIZD4_002050"
     CDS             4042..4803
                     /locus_tag="ACIZD4_002050"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGC5990956.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="ACIZD4_002051"
     CDS             5183..5692
                     /locus_tag="ACIZD4_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGC5990957.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="ACIZD4_002052"
     CDS             complement(5767..6306)
                     /locus_tag="ACIZD4_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGC5990958.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="ACIZD4_002053"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="ACIZD4_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGC5990959.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7319..8170
                     /locus_tag="ACIZD4_002054"
     CDS             7319..8170
                     /locus_tag="ACIZD4_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGC5990960.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8198..8833
                     /locus_tag="ACIZD4_002055"
     CDS             8198..8833
                     /locus_tag="ACIZD4_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HGC5990961.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="ACIZD4_002056"
     CDS             8853..9626
                     /locus_tag="ACIZD4_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC5990962.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="ACIZD4_002057"
     CDS             10034..10831
                     /locus_tag="ACIZD4_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HGC5990963.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="ACIZD4_002058"
     CDS             10809..11222
                     /locus_tag="ACIZD4_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HGC5990964.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="ACIZD4_002059"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="ACIZD4_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGC5990965.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="ACIZD4_002060"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="ACIZD4_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGC5990966.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /locus_tag="ACIZD4_002061"
     CDS             15999..16559
                     /locus_tag="ACIZD4_002061"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HGC5990967.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="ACIZD4_002062"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="ACIZD4_002062"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGC5990968.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="ACIZD4_002063"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="ACIZD4_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGC5990969.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="ACIZD4_002064"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="ACIZD4_002064"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGC5990970.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="ACIZD4_002065"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="ACIZD4_002065"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGC5990971.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="ACIZD4_002066"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="ACIZD4_002066"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGC5990972.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="ACIZD4_002067"
     CDS             21906..22484
                     /locus_tag="ACIZD4_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5990973.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="ACIZD4_002068"
     CDS             22536..23018
                     /locus_tag="ACIZD4_002068"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGC5990974.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="ACIZD4_002069"
     CDS             23135..23509
                     /locus_tag="ACIZD4_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990975.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4286 c         5115 g         6644 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgac
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcaccgggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatggaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga tgaaaataaa ataacaaaca atttgtaaag ttaacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc
    23641 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    23701 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    23761 ggtatgctta tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    23821 gttaag
//
LOCUS       DBBGRF010000046        22980 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000046 DBBGRF010000000
VERSION     DBBGRF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.046"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(67..1488)
                     /gene="tyrP"
                     /locus_tag="ACIZD4_002070"
     CDS             complement(67..1488)
                     /gene="tyrP"
                     /locus_tag="ACIZD4_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HGC5990976.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1731..3608)
                     /gene="tdc"
                     /locus_tag="ACIZD4_002071"
     CDS             complement(1731..3608)
                     /gene="tdc"
                     /locus_tag="ACIZD4_002071"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HGC5990977.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3899..5155)
                     /gene="tyrS"
                     /locus_tag="ACIZD4_002072"
     CDS             complement(3899..5155)
                     /gene="tyrS"
                     /locus_tag="ACIZD4_002072"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGC5990978.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5267..5472)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5735..7036
                     /locus_tag="ACIZD4_002073"
     CDS             5735..7036
                     /locus_tag="ACIZD4_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HGC5990979.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7105..7704)
                     /locus_tag="ACIZD4_002074"
     CDS             complement(7105..7704)
                     /locus_tag="ACIZD4_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5990980.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7959..8840
                     /locus_tag="ACIZD4_002075"
     CDS             7959..8840
                     /locus_tag="ACIZD4_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGC5990981.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8853..10463
                     /locus_tag="ACIZD4_002076"
     CDS             8853..10463
                     /locus_tag="ACIZD4_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5990982.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPVMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10540..11199)
                     /locus_tag="ACIZD4_002077"
     CDS             complement(10540..11199)
                     /locus_tag="ACIZD4_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HGC5990983.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11482..12147)
                     /locus_tag="ACIZD4_002078"
     CDS             complement(11482..12147)
                     /locus_tag="ACIZD4_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HGC5990984.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12294..12899)
                     /gene="dhaL"
                     /locus_tag="ACIZD4_002079"
     CDS             complement(12294..12899)
                     /gene="dhaL"
                     /locus_tag="ACIZD4_002079"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HGC5990985.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(12927..13937)
                     /gene="dhaK"
                     /locus_tag="ACIZD4_002080"
     CDS             complement(12927..13937)
                     /gene="dhaK"
                     /locus_tag="ACIZD4_002080"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HGC5990986.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(13912..14307)
                     /gene="dhaM"
                     /locus_tag="ACIZD4_002081"
     CDS             complement(13912..14307)
                     /gene="dhaM"
                     /locus_tag="ACIZD4_002081"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGC5990987.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14461..14781
                     /locus_tag="ACIZD4_002082"
     CDS             14461..14781
                     /locus_tag="ACIZD4_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HGC5990988.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14893..15750)
                     /locus_tag="ACIZD4_002083"
     CDS             complement(14893..15750)
                     /locus_tag="ACIZD4_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGC5990989.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(15858..17162)
                     /locus_tag="ACIZD4_002084"
     CDS             complement(15858..17162)
                     /locus_tag="ACIZD4_002084"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC5990990.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17159..17668)
                     /locus_tag="ACIZD4_002085"
     CDS             complement(17159..17668)
                     /locus_tag="ACIZD4_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5990991.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17843..19978)
                     /locus_tag="ACIZD4_002086"
     CDS             complement(17843..19978)
                     /locus_tag="ACIZD4_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HGC5990992.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(20061..21716)
                     /locus_tag="ACIZD4_002087"
     CDS             complement(20061..21716)
                     /locus_tag="ACIZD4_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC5990993.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(21718..22032)
                     /locus_tag="ACIZD4_002088"
     CDS             complement(21718..22032)
                     /locus_tag="ACIZD4_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGC5990994.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            22202..22462
                     /locus_tag="ACIZD4_002089"
     CDS             22202..22462
                     /locus_tag="ACIZD4_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGC5990995.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            22476..22790
                     /locus_tag="ACIZD4_002090"
     CDS             22476..22790
                     /locus_tag="ACIZD4_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HGC5990996.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
BASE COUNT         6486 a         4728 c         4132 g         7634 t
ORIGIN      
        1 aactattcac ttggcaggac ctcctactaa atcagcgaca aaacgtcggc tgaaagactt
       61 atttttttat ttttcttcta aacttttttc tacctcaatc ccccaagaat ctttcttgaa
      121 gtgattgatg atcaatggaa taacgaacat gaccactgtg atagctgcta ctaataatgc
      181 atcactcaat gtcgctgtac ctaatgtagc aaatacgaca acgatgatag agaagatcag
      241 catgcagctg actacccaag ctaatccgtt tccgttttta ccaattcggt aaggacgttc
      301 gaattctgga tgtttcttac gcattttaag caatgaaaca gcaatcaaaa tgtacacgat
      361 acaataaata acagttgtag catttgtaag tgtcaagaat acagcactta cgtcatccat
      421 tacaccataa agcaaagcaa ataatgaaat aacgattgat tgtgttagaa cgacatttct
      481 agatacgccg tatttgtttt ctttatggaa tccgaatttt ggtggaagga atccttcacg
      541 agctacttgg atgattgttt ttgatggtcc agtaacccaa gctgataatt gtaaaagcac
      601 accaataaat accatgaagc tgaagatatt tccgatcact tctggtaagc ctaggatttg
      661 acagtcaatc aagataggct gcgtgatatt tgctaattcc atttttccat ctggtacgac
      721 atttgctaca agcatcgcat tgatgacatt caataaaact aatccgatca aagcgataaa
      781 tacgcctttt gtataatttt ttgttgcgtc tttcaaacga ggcatgtaaa cagaactcat
      841 ttcgatccca acaaaaataa atgtgatacc agctaagtat ttcaatgaat caatatgttc
      901 caagtcaggg aaagcttttg accatgaaaa gtcacctaga tagccgtttg agactagtcc
      961 gactttgaag gctgccaaaa cacctaaaac gaacatgatg actactggga tatatacccc
     1021 tagccataca ccgatgttcc cgccgacttt tgccatatcg aatttcaagt tcaagatcgt
     1081 gatgatccag tagataacta aaatacaacc taaaacgaac cagtgattat tgccaagttc
     1141 tacattacca aatgtgtttc ctaacaatgg tcctaaagta gaagcgacca ttaccatacc
     1201 tgggaacatt tgcacccata atagccatgc aacgacaaat ccccatttgc tgcccagtgc
     1261 tgtttttacc cataactgag gaccgccttc ttgaggaagc atcgtggaaa gctcaccgga
     1321 aaccattgat atcggaccgg caaaaaacaa aactgcaaaa attgaataaa aaatcaatgt
     1381 ccaaccgact gcggctaacg taggaatact ccgaaccgtt gcacacagtg ccattgtcag
     1441 accgataaag gtcccaagac ccattttact tacttcagat ttactcaccg ttgacactct
     1501 ccttgatttt ttggataaaa taacggtgtc tttgaagtag tttcagcaat aaacgaaaca
     1561 attcagcgaa tatttgaggg gattctttga gtttattgct tgaagggttt cttcaaagac
     1621 aacctcaaaa caaagggatc gaagagctta ggtctcccct tgctcttcag atccaaacat
     1681 gcgtcagaaa cagttagtat tcaagctgtt ttctaacatg attaccttgc ttattttgct
     1741 tcgcttgcca ataattggtc tgcgtagatt ttttccaatt tttcttgaag agctgctttg
     1801 attttttcag catattcttc aaagtgttct tctttgttca tgtatggtgt cattacgctg
     1861 gcacgcaata cagttacttt tccggcacgg ttccattctt catctgagaa tcctagttgg
     1921 ttcacaaatt gtaatgggct gttgccatag tctgggatag caaagtcagt atgtgaagtt
     1981 aagaactcat taccgtaaat gcttcctttc acgtatgaag aataatcata tacgtcatgg
     2041 ttcaatttat tcattgcaac taagtcatcg ttgccttttt ctttgaatac atagtctacc
     2101 atattgaaat ctggataagt taatggatga acttcgattt ctttgtctcc tactttaaat
     2161 gacaagtcat tcaagaagtt gtagaaacga tgtgcacctt cgattgatgc acccattaat
     2221 ttaccatatc ctgtgacatt caaaggtaag acatggtgtg ctgcccaaac gctggctgct
     2281 gttgcccctg cttttgaacc ttccaagata taagccccaa gtaatgctgg gatatctgcg
     2341 cctttttcaa atacatatgt cgcaaagtaa gagataacgt ctctcatgcg gatatctttg
     2401 atgacgatac caccggcaga atatggaaca tagcccattt tatgtgggtc aatcgttaca
     2461 gattctgctt cttcgattgc tttatatgca ctgtgtactt cttctaagat ataatctttg
     2521 ttttctgtaa agacattgta tttgtaatga acatctttta aatcttcaaa tggaatgaag
     2581 ttgttgtctt cgtctaagaa aatcgcacgg ccgtatccgc cataagcagc atctacgtgt
     2641 aagtagaagt aaataccgtc tttttctaat acgcgacgca atgcaacgat tttatcgata
     2701 ccgtcgattg ctccttcttc tgttgatcct acaacaccga ctacacctag gattggtgtt
     2761 ttttcagctg ctagaccacg aacgattttt tcaagttcgt tgatgtccat gcgatagttg
     2821 tggtcaactg gcactggaat cacttggtct aaaccgatac cgatgatgtc ggcagctttt
     2881 agccatgaat agtgtttagt ttgtggaacc aaccattttc ctaatttttc taaatgtttt
     2941 ccgctacgtg ctgagtgagc tttgatttcg tcgatttttt ctgggacgct gtctaacaga
     3001 ttcatgattt cttctgttga caagttcatt aattcccaat cgctttttcc agcaactagt
     3061 tcaggtgtca cttctttcat tgcaagcggc aatgatttga tgttgcgggc ataccaaagt
     3121 ccttctaagt ttgctaaaga accatcagca acgatgtggc cccagccatc tttatagctc
     3181 attaattttg caaattccat tcctacttct tcttccattt ggcttgttgc aggagaagat
     3241 tcataggcaa cgttattacc attccatagc atagcaaaat tgtacgctag taaagatggc
     3301 atcaatgttt cagagttcat atgaccccag taacgtccgg cattatgcca aggaacggaa
     3361 tgggtacgca tccgcgctga aatttctgat agaacatcct ttgttttatt cacagtgtgt
     3421 tcaaaactag cactgctttt ttcttctggc gtaataatag gcatgtcttg aggcatgtag
     3481 ttttgacgcc agcctaaatg ttcatccacc aattcattca acaaagcttt atagatttgg
     3541 ccgttctcag ctttgtcccc aatgaatagg gcatttaggt ttagatcttt cgacaatgat
     3601 tcactcatag tgaaaccctc ctaaaaaaat atttaaattt tgtcgagccc tacattacac
     3661 ctgttcttct attctgtaaa ctaagttttg gcctgatttt taatcatatt ttaatatgta
     3721 tcaattatcc gaattgttca cacttttgaa ataattaaaa aaaacgaggg aatttacaaa
     3781 tgtaaactcc ctcgcaaaga ttgtattaac gacaaccagc gttctatttt aggatgggtt
     3841 tcaaaattgg aatgttgtaa tagtatttcc ctttttcaag gtaaaaactt actaaattct
     3901 aatcaattac tttggccaaa aagtaatttt tcttaccttt tcgaataacc acaaacttac
     3961 catcgaattc atcggatgga tttatgacaa aatttaaatc ggtaacgcgg tcaccgttaa
     4021 tacttatagc tccgtttgaa acatcttcac gtgcttgacg tttagatggt tcaatttttg
     4081 tggaaacaag cagttccacg atattttcag gtgtgcttga aatttcaacg ttcggcattt
     4141 taccgaatcc ttgcgcgatt tcttccgcat ttagttcttt aatatttcca gagaacaatg
     4201 cttgcgttat tttttgcgct tctttcaagt cttcttcact atgcacaaat cttgtaactt
     4261 cttctgccaa acggcgttgt gcttcacgtt tctcaggttc tgtctctact tttttcgcta
     4321 agtcttcgat ttcttcttga gacaagaaag taaagaattt caagtatttc actacatcgc
     4381 gatcatcttg attcaaccag aattggtaga actcaaatgg tgaagttttc ttcggatcaa
     4441 gccaaacggc accgcctgca gtttttccga atttcgttcc gtcagccttc agcatcaatg
     4501 ggatcgttaa accgaacgct tctgcttctg gtccttctaa ttttcggatt aggtctaatc
     4561 cagctgtgat atttccccat tggtctgctc caccgatttg caattgcaca tcgtatgttt
     4621 tatgcagatg caaaaagtcg atagattgca ggatttggta agtaaactct gtaaatgaga
     4681 ttcctacttc caaacggctg gcaacgatat cttttgctaa catcgtgttg atgttgaagt
     4741 ttttaccgta gtctctcaaa aattcaagta aagagatttt tgacaaccag tcgtagttgt
     4801 tcacaaatgt gatatttgca tctttaccaa acaattttct catttgattg gaaagtgcgt
     4861 ccacgttatg ttgcacttgt tccatcgttt gcaacacacg ttctgttttg cggccgcttg
     4921 ggtcgccgat cgttcctgtt ccgccgccaa tcagaatata tggatgatgg cctgccaatt
     4981 ggaatctttt catcatcata aatggaatca aatgtccgat atgcatcgaa tcaccagttg
     5041 gatcaacgcc gcaataaagt gaaatgctct tttcttcaac gagctcgcga agtctttctt
     5101 cgtttgtttg ctgattaatg gcgtcgcgcc aagttaattc atcaataata ttcattttac
     5161 tgacctccgt gtagtttttt tatgaaagca ggaacctgct agcatgtgta attaattatt
     5221 tcttcaggat aggataggaa ataaaaaaag tcccttggca tataagccaa gggacgaaat
     5281 ctcgcggtac cacccaattt gtatgtctag atatccaaca tacctctcga acatttaacg
     5341 ctgtcgcgtg gcaatcactg ccaaagactc ctgaaatgta attcgcttta aagcatgtac
     5401 tggtttgcag cgaccaccag ctttctgaaa cattggcttt aacaactact tcgtttcgat
     5461 cttcgtcttg ttattattaa tatgtgtcta tcatagagcg caactttttc tttgtcaaca
     5521 gaaaaaggat atttttttta aattcctcat tttttctttt ttgaatccgc tctaattccg
     5581 aacattttat tttcaattat tgttaaaaga aataactttt tctgtatttt ttctgcaatt
     5641 tatcgagaag tcactttact ttgcctctta ttctttcttc gttacaataa ggaatgggac
     5701 aagtaaaaaa atgaaaaagc aagggacgag gtatatggaa aaaaagcaaa aaattatttt
     5761 aggagccact tctgctttaa ctatcgttat tttaattcta agtttgtttt ttgtcatccg
     5821 atcatctaca aaaaaagaac caatcattcc tgaaaaaaaa ataacagaaa aagcaaaaga
     5881 accgacagat gataagcaac aactagttac tcaagcaaaa aatctggctc aaagctacga
     5941 ttatgaccaa gcgattgcgt tattggaaaa agatagtaag aacggatcta ctgaaacaca
     6001 acagcttctt caaacactaa aaaaggagaa agaacaactg atcgactggt ctgatcctac
     6061 tcagatctct catgtctttt tccacagctt gatcgtggac ccgcaaaaag ccttccactc
     6121 tcaacaggca caaggataca aagattatat ggtgactgtt gaagaattca accgttcgat
     6181 cgaacaactt tatcaaaatg attttgtttt agttaatttg aatgatttga tccaaaaaga
     6241 cgaacaagga aatctttcct ttaacgggct tgcgctacct gaaggaaaaa aaccattggt
     6301 tctttcacaa gatgatgtca gctattatga atatatggat aattccggtt ttcctagccg
     6361 attggtcgta tcaaataaca atgaaatcaa aaatgtctat aaagagaaag ataaagaaga
     6421 aatcggtgac tttgacatgg ttcctctgat cgatgccttt gtcaagaaac atcctgattt
     6481 ttcttatcga ggcgcaaaag gtaccttggc cctgacaggt tacaacggag ttttaggtta
     6541 tcgaacatca aaatctcaat atggagacaa tgaaaaaaca aaaaaagaga ttaaagaagc
     6601 taaaaaagtg gcggaacagt tgaagaaaga cggctggagc tttgcttccc atacatgggg
     6661 tcacttgaat atgactcaag cttcactaga agatgtaaaa aaagacaatg aattgtggca
     6721 gcaagaagtt gcacctatcc taggaaaaac aaatattctg atttatccat ttggtgcaga
     6781 catcagcgac tggcagcctt attcagcaga aaatcaaaaa tttgcttact tgaagagtca
     6841 aggtttcgat attttctgta atgtcgatgc ttctacacca gcttggggac aattaggtac
     6901 ggatttctat cgaaatgctc ggatcaatat cgatggcatt cgttttcaat ctgatttaga
     6961 cggaaaaaat cctattcttg atccattcat caatgtccat gatgtctatg acaaagaagc
     7021 acgcgaatct gcttgatttt acgtcattta tgaaccaaaa aagccgaact gacattttat
     7081 cgtcagtttc ggctttttta tgctttattt cttcttcggt gcgattccct tgatcaggac
     7141 ttctgtccat tctgctgtat atggaagcag ttttgcgtat atctccggct tagaaattcc
     7201 ttctaccatt gcttgaaaat agaggatcaa gaactcatcc gaatatttca aatccacttt
     7261 tccttctttc cgccctcgat ggaaaagatc aagcatgata ctgaaacttt cttgcgtata
     7321 cgcatccatc gcgtcagaaa attctttttt ttcttttttt gtatagtatg tcatcaaatc
     7381 gatataaaat tgtttgttca ctcgattgag ataacggatt ttgttttcac tcatggcaat
     7441 cagtgtttct tcaaatggaa gattttccgc aatcaacgct ttcgcttctt gccctaaatc
     7501 attcataaat gcaaaaaata cttcataaat cagcccttcc ttgctgccaa aatatttaaa
     7561 aatcgtcgct ttacttacct gagcgttctc agctacctta tccattgtca ctccagcggt
     7621 tcctatgtct gtgttcatca agtcaaaagc tgcttgtaaa atctctttct ttttctcttg
     7681 tgctctcttt tcaaaaccgt tcatttgtag agcctcccgt aattttaaac ttttataata
     7741 tatatagttc aaatttattc tgaggtttat tataactatc tattgagaaa gtatcaagct
     7801 agcaattcct tgtttatgaa ttcattgaca gaaatttata aaaagaatat tatgtactaa
     7861 aataataaaa aaaagtttta taaaaaggta taaaaccttt ttattaaact atttaatctt
     7921 gtttagtata tatttttaga aaaaggagtg gggtttttat ggcagaaatc gtcaaagtca
     7981 cacatttgaa aaagagcttt ggtcgtttcg aagctttaaa agatgtctct ttcaccgtac
     8041 attcaggtga agtcgttgga tttatcggac caaatggttc tggaaaatcc acgacgattc
     8101 ggacactttt agggattata aaaaaagacg gcggaacggc aacgattttt gggcaagatg
     8161 tatgggaaga tagtttatct atccatgaac gtctttctta tgttccaggc gatatctctt
     8221 tgtggggaaa tttgactgga ggagcgatca tcgatctctt catgaagctt catggaaaag
     8281 ggagtgctca aaaaaaagat gaactgattc aacgtttctc tcttgatcct aagaaaaaag
     8341 caaaaaacta ttcaaaagga aatcgccaaa aagtgggctt gattgctgct ttggctgttg
     8401 attcggatct ctatttattt gatgagccta cttctggttt agatcctttg atggaaacga
     8461 ttttccaaga agaagttgaa aaattgaaag aacagggcaa atccatccta ctttcttctc
     8521 atattctcag tgaagtcgag cgactagcgg ataaagtcgt gatcatacgc gaaggaacac
     8581 tcgatgaaga aggaacactc gatgaattgc gtcatttgac tcgttcgacc atcactatag
     8641 aaacagaagc agagaatagt cacttagcac aattgaacgg tgtccatgac tttgtgcaaa
     8701 aaggtcacct cgctcaattt gctgctgata acgaagcttt cgatgtgatt ttagctgaag
     8761 cgtccaaatt aggtgtgaaa aaatttgaat ctattccacc gactcttgag gatttattca
     8821 tgagacatta tgaaggatga ggaggaagcg aaatgactga taaattttca cgctggtcca
     8881 cccttttttc tcaaaacctt agccgtgact ggaaaaagat cctgatatgg ctagtcggtg
     8941 tcactgcttt ttctggtggt tttgtccctg cgtttgaaga attgacttcc ggacaaggat
     9001 tagctggatt atacgaaacc ttgcaaaacc cggtaatgat tgcaatggtc ggaccaactc
     9061 cagcttcgaa tgctgctgag tatactttag gagcgatgta tgcaaatgaa atgttgcttt
     9121 tttgcagttt gtttgctgct gtgatctctg ttttacacgt ggtgagccaa acgagaaaaa
     9181 aagaagaact tggtctgatt gaacttattc gttcctttcg agtcggacgt caagcaaact
     9241 ctttagctgt catcgctgaa agtattctga tcaatttgct tttagcaata tcgatcagct
     9301 gtacgatgat ttttttccaa gcggattcga tcactgcaga aggtgcttgg ctttttgggc
     9361 tatctgtagg tagtatgggg attttgggga gtgccgttgc actgtttgct gcacaactga
     9421 tgccaagttc agccagttcg aatggtctgt ctttagcgtt tttaggtgga ctttaccttc
     9481 tacgagcaat aacagatgta gctgattcct ccctttcgat gtggaatcct ttaggctggt
     9541 cttatttgac ctatccattt acaactaaca actggattcc tttgctttat ttgtttttgt
     9601 tcagtctaat cttgataatc agttcatttg ttttagagga acatcgagat ttgaacaccg
     9661 gctatatccc cgaacgtgaa ggaaaaccgt atgctaaacg ttctctttta tccttgcgtg
     9721 gtttattatt ctatctaaat aaagggatga caatcagttg gcttatcact tttggtttga
     9781 tgggggcggc atacggctct atctacggga atatgcaaca gtttttagaa agtaacgact
     9841 taatgaaaca gatgtttatc caatctggcg tctcaattga aaaaaacttt acaagcacga
     9901 tcatggtagt cttgatttgt ctagctgcta ttttaccaat tgctagcatc aatcgtttat
     9961 ttacagaaga aacccacgga cgtatgaatc agctgttcgc aacaaaaatt tctaggaacc
    10021 aactttattg gaccaatatg ttactagcta ttctatttgc tatattggca atcctgatta
    10081 gttctggtgc actagggctt tctgctttgg cttcgatgaa ggatgcgaaa gacatggatc
    10141 tattgatgtt tcttaaagcc gggttcaatt tcctgcctgc cgttttagtg tttatcggaa
    10201 ttagtggctt tctattcgga tggcttcctc gaatcggtaa acttgcttat atctacttag
    10261 cttactcctt tgcactcaat tactttggcg gaattttgga tttaccagaa tggttttcca
    10321 aaacagctgt ccctagctgg gttccacgga tgccaaacga ttcttttgat ctttccgtgt
    10381 tccttacgtt atcatgtatc agccttgcac tgttcgtcct tggttctatt ggttataggc
    10441 gaagagactt actagaagga taataaaaaa gcatgtacaa tttcatgcta gcctccaaat
    10501 ctgggtcaaa aatccaacat ttggaggtca tttttttatt tacaagtctt ctaactgctc
    10561 tttatcaatg atccagactt ctcgattctt tctttttaca taaccattct cctctaataa
    10621 tttaaatttt ctagataaag tttcgggggt cgtaccgata aatgcagcaa gttctttcat
    10681 tttcattggc aggaaaaagt gatccttccc tgtcgcttta gctaagtcaa gcagatagac
    10741 agcgactcgt tcttctactt tttccatcat caaaaaagtt gtctgctgct gtacttttgt
    10801 taatttctca acgttgattg ctaaaagttt cagactaagg gcgggataat gcagtaagag
    10861 ttccgagaaa tctttttgtc tcaatatgca aatttccgtt ttttctagtg cttcgccaaa
    10921 taaagactca tttggaacgc ctagcaactg gctctctccc tcatatccgc ccggctctat
    10981 tactcgtaaa agctgttcct ttccgctagc agataattga tacactttca tactgccgga
    11041 ggccacgatc actaattgag gttctccatt cggcgcaaga atctgttctc ctttttccac
    11101 atagtgatgt ttgacaagtg cgtgtacttt ttcttgatct tgctgtacta agtgattgaa
    11161 caaaggaaca aatgaaacac ataaatgatc atgactcata atctctcctc cttctaaaca
    11221 gctatttcta ataaagaaac ataacttccc ttattccaac tgataatttt cttttatcat
    11281 agcataaacg tcaagcgaac cagataccag caaatagagt ggatttcttt ttgtcccttg
    11341 ctttattttc cttcttttga gaccttaagt aattgattcc tatcaatttt ttaaatattt
    11401 actttttgaa taatcaaaaa caaaccttca ctcgcaagcc gagagtaagg tttgtttttc
    11461 gcattgctta tttcgtgttg tctattgaaa tttttccgca cctagctttt gatatagtgg
    11521 tgctagttct tgtaaggttt cagcggttat ttgctcaacg tgttcgattt cttgcggata
    11581 gaagaatagt ttacccattt gaaaggttcg gtctctcatc gcttttttca actcttcttg
    11641 tttctttgta tcggacaaat agtcagacaa agctaagtgg tcgtcaagtt catgttctgg
    11701 ttgcggccat atgtaataat ccttgatatc gactgttttg ctccactctt tcagtatcgc
    11761 aagcaactgg ttatacgctg caatgctacc atatcgttct tcgcttttat aatgttggta
    11821 catcaaatag atttggtatt gtttttgatt caacaaaact gctagacagg cattctcgtc
    11881 ttgacgagat tcgcttcggt acgcgctcca aaaatgactg cgtaaattcc agccattcgt
    11941 ccagctttcg attttaggtt tgctcatgcc gtacatatca ggcaaaagtg cagctgtctg
    12001 gagctgaatc tctttccatt tttgccagtg ttctttatat tctttcttga tttgttcaat
    12061 cttatctgtt ggatggctct ctttgagctg tttgaatgcg tagattggtc gatcaaacaa
    12121 ctgataatct gattttccaa gttccattgt ttcgcctctt tccgttatct tttgtattct
    12181 acctgaattt tgcgatatgg acaaatagag gttgtgaaaa agctgttctg catcaagtca
    12241 taagaacagc caaacaaaaa actgcgatga gcatcaccgc agttttattg aacttaaggt
    12301 tgattgatca catctaaaag cgttgaaaat aaaatggcac tagaagcagc tcctgggtcg
    12361 atatgtccga ttgcacgctc tcctagatag gaagctcgtc cttttttagc taccaagact
    12421 ttggtgtgtt cttttgcctg gtcaatgatt tcttttgtta aattccctgc cttcaatgcc
    12481 tctgtgactg gcagccaaac atctaacatc gttttatcgt cagcttctgc ctttcctcgg
    12541 ctttgaatac ccgctgttcc ctgctcgatc acttcgccta atttttcttg agaatcaata
    12601 gaatcgacct cttttgtcgc tttcatcatg ttcatgaatg cagatccgta taacggacca
    12661 gaagccccac cgactttcga tatcatcgcc atagagaata ctttgaatgt atcgctgatt
    12721 gtttcaggat gatcggcttg aaaagcttct tcataagctg aaacccctct tcccatgtta
    12781 tttccatggt ctccatcgcc aatcggggta tctagatcac tgagatattg tttgttctga
    12841 ttgattgcct ctgcaaattg cgtgagccat tcttggattt cttgaacggt tagtttcata
    12901 ttatcaccct tttatcttga gattttttac catgaaatcg tctgtacatt gctttctaaa
    12961 gaatctttcc attgtgtctc cgtcaagtcg atcagtgtta gagaaagacc ttgcatatct
    13021 agtgaggtca taaaattacc gacttttcgg aaaactacat tgacgcctct ttcttccaac
    13081 agagctaaaa catcattcat gaacacgaac tgttccatca aaggcgtccc gcccattccg
    13141 ttgactagta cacctgcttc ttttggtaaa ttcgagtaat catctaaaat cttagtaaca
    13201 agttcctttg ccagtacttt agaaggctgc atcttttctc gacgatagcc tggctcaccg
    13261 tggataccaa caccatactc gatctcatct tctcctagtt cgaatcctgg tttccctact
    13321 tctggtacag ttgctgctcg aagcgctaga ccgatcgtct tagttgcctg tacgaccttt
    13381 tctcccagtt ctttcaactc agctagggaa gcaccgtttc ttgctgcatc gcccacgatt
    13441 ttgtgtacaa ggacagtacc tgcaactccg cgttttccag cagtatacgt actattttca
    13501 acggcgatat catcatctac gatcacactt tctacttcaa tatcgtccat agcagctaat
    13561 tcctttgcca tatcgaagtt caatgcatcc cctgtataat tcttaacgat cagcaaaact
    13621 ccttttccac tatcggcttc cttaatagcc gtctgaatct gatctggagt tggagaagta
    13681 aacacatcac caagcaccgc tgcacttaac atcccttccc ctacaaaccc ggcatgggat
    13741 ggttcatgtc cgcttcctcc accagaaacc aaaccaactt gttccgcttt ctgattcttg
    13801 gctacaacac gggaagattc tacacgatga acaagttctg gatagctttt tactaatcct
    13861 tccagcattt cttcgacaat attgcttgga tcattcatga tttttttcaa tttattccca
    13921 tcctttcttt ccggcatttt gtgcttctgt taagatttgc tgagtatcat ctgttatacc
    13981 ggcagtgatg gctgctgcaa aagctccttc cactaaaggc gcatccacca gatgataacg
    14041 ttgctgctgc tcttcttcca acatgtcttt tgccagttcc gagttcaata ccgcgctacc
    14101 gatatccgca aaaacaaaat aactagctgc atcgcttgat tcattgactg cttctacgat
    14161 tttcatcggg tctgatccga tctcgccatt tattccgccg agagaaaaaa tttgcacctc
    14221 ttcggatttt tgcatctgct caatcatttc tttaatacca tctgttactt tttgactatg
    14281 agaaataagc aaaatacttt ttttcacaag aatcttcctt tcttttacat agttgctaac
    14341 gattggtttc gctttcatta atgaacaatt caagtatata ataaatttct aattttggga
    14401 aaatatgtgt agtgcttctt gaagtttgtt atactttaat taaaagagag gagtgatcga
    14461 atgattacaa caacaacgaa cagtgtagag ggaaaagccg tagtagctta taaagggatc
    14521 gtttttggtg aggtcattac tgggatccat gcatttaaag acttggaggc ggggttgcga
    14581 aatatctttg gcggccgctc aaaaagctat gaaaacgaac taatgggtgc aagagaagaa
    14641 gcacttgccg aaatggccga acgtgcaaaa gcattaggag ctgatgcgat cattggcgta
    14701 aaaatggact atgaagtatt aggcagcgac aatggcatgc tgatggtcac atgtagtgga
    14761 acagctgtct ccacgagata agtaggggac atctgtttta ataactaaag agagatggga
    14821 catgtagtgg cactcaagaa ttagattttt cagtctaact tcgaggtact ctaccttccc
    14881 atcctctctt ttttatttct ttttgcggat gattccgtaa gctgctgcga ctaacacacc
    14941 cgcccctgct aaggaataac tgacagaagc tgttttttca tttgtttttg gcaaagtctg
    15001 acttgttgat ttggatggct ctgtcgtttg ctgaactgtt tctgtcgtgc ttccagaggt
    15061 cactgatttt tctcctgccg aatgcaaaat atcttttatt cgttggaaac tagctgctaa
    15121 gtcagctttt tttgcttcaa aatcattagc aactgtttgt gcttcgctga tctttccgtg
    15181 gattgcttga ctggccgctg tgatatccgc ttgagtttga cttagctttc cagaagctgt
    15241 ttgagcaacc tgatttaatt gctgattgaa ttcttttgct tgttggatct tcccgtcaag
    15301 atctgtttgg acagcttccg cttttgcttt cgcttcggca agctttttct caagttgtgc
    15361 acggtcattt cccactttat ttttaagatc agctaaatct tgatcgattg ctgcttggtc
    15421 ttctttcaat ttgttttttg cagcttctaa tgcttcttcg agttcttttc ttttattttc
    15481 caagtcttgc aaatgatcga tttggtcaga agaggtagaa ctatttattg atgtatcttc
    15541 tgaagatgaa atcgtttctc ctgaattatc tgtcggtaca ttggaagtca tttctgtttc
    15601 cgaggcaccg ttttcagcac cagaagagct tatggttgtt gaaggttctg tttgagcagg
    15661 ttcagaagtt tccgcaaaag ctgtctgtcc caataagaaa atactggaaa cagcaattgg
    15721 ccagattaac ggcttcattc tttttttcat cacttttccc atccttacta ctttttaact
    15781 aatttcttat tataagcaaa aatgtttgga agaaccataa acacaacagg ctgtttgtct
    15841 aaaaaacggt gcatctttta tttttttgta cgttccgggc ttttccatgt cccgcttcca
    15901 taacctaaaa tcgttttgac tgctggaatg aaagtcgtca cgatcgttat cgcgttcact
    15961 atccagaaca aaagcatata tagtggtgcg aaaagaaggt atttcaattt tcttcgtcga
    16021 tcatctacaa tcagcgaagc tagcaactgg aaaaatcctg cgaccatttc aaagcagatg
    16081 aacacaaaac tgaatgtaaa agtaatataa atctgttcgt agtttccttg atatacataa
    16141 tgcccgatta atccagcaaa aagaactacg gaaatacaaa agaatattga ccagacaata
    16201 ctcaatgttt gatcaatgaa gatgatcgtt cttccaatat gtttaaaagg atggagcatc
    16261 acttttttga aattcgtcag ccagacttct gttccacctt ttgcccaacg ttttctgtgt
    16321 cgatatagca tcttcaacgt cacaggtact tccatgaaaa agataatctc aggagcaaaa
    16381 acagataacc agtcatttaa ctgatgatcc caagcaatac tgatgtcttc tgtcgctcga
    16441 tcttgtctga atccgcccac atcgatcaag gcttcttttc gatacatcgt atttgctcca
    16501 ctgtacgcat aaagaccacc gaaaacagct gactgtgttc gtttaatgat gcccacgata
    16561 cttgagaatt caaccgtttg agattttgca atcaatttgg tacgattttg gacatccata
    16621 tttgcagtga ccgcagcaat atgtcttgca ccagggcgaa tgaaataatt cacataccta
    16681 atcagtgcat ctggctccgg taccgtgtct gcatcattgc ttaaaatcaa tttccctttt
    16741 gcaaaggcaa gtccgatatt aaacgcgtgg gcttttcctt tatttttttc gatccgaacc
    16801 acacgaagat tagcgtattt tttcatcagt ctagctaata tttctggtgt ttggtccgtt
    16861 gaaccatcgt ctgtcactaa tacctcatag ttgtgataat tcaatttcgt catcaaatac
    16921 tcgattgtat attcgatcac aatttcttca ttatgggctg gcaccatgat cgtgatgaac
    16981 ggttcgacac tcaagggaac atctacccat tctttttgct tatgtttgta taaaaacaca
    17041 taacaccaga caccaataaa ccatacaaat ccgcctaaaa tcggataaga aacgagaaaa
    17101 aaatacataa tagacaaaca agtatctaag aataaattac ctgtatgggt gattgagatc
    17161 atttcagttc caccccattt tctttataca aatctgcaat gaatgtcgta tctagatttt
    17221 tctcttcgga gacagaataa aaacggaccg tttctctctc ttcttttgtt ccaaaacgtt
    17281 ccgtatacac ttcttcaagt aattcttgtc tttttttcaa tttttcatct tcatattcaa
    17341 aagatttatt tacttttttg tatagatttc gattgttcca cctagtcaat acaaatgagg
    17401 taatcaggaa actgaaaaaa atcaatacaa aaaagccgat taagaaatac agcattttct
    17461 tttctgataa aaaagcgtac aaggaaaaat ccttggctct ttctggtctc gttaatggga
    17521 aaaagaccca tataaaagga agaacaacga tcatccatcc taaaagagcc actaacgttt
    17581 gccaaatctt taaccagtaa ttaccttttg aaaaatactt atctttcacc aaaattgatg
    17641 caacttcttc tcttgttact tttttcatat cctcacctca cgtttttttg ttacgacgta
    17701 ggagtttacc atacatttca tttcttttca cataaagtgt tcctaaattt ttcctaagaa
    17761 aaagaacaaa acatttctca tcagcaaatg aaaaatattt tgttcttttt atcagttgtt
    17821 ctttttattt tttatctctt aattatgttg ctctttccaa tacgacaatg cttttcattc
    17881 ctctagatat cgccgtgtac atttgtctgc gtcttctttg ctcatctcca tcgttttcaa
    17941 atggatataa gattacatga tcaaattcca gtccttttgc tagactcaaa ggaatgattt
    18001 ggcagttttc taatccatat gaattttttt taatcgattc ttgtagcgtt tgggtttcct
    18061 cttctgtttg ggtgataact gccgcttttt ctccttttag agaaaccaaa atctcagcta
    18121 gtattttcaa caattcttca gaggatcgaa aagagcggta ttcgggttct tttccttgcg
    18181 gtcggatcga tacgatgtcg atcttctctt gatccacagc ataggttttg aaaagctctg
    18241 tgattgctcc gctagaacgg taactatttc taagatcata ccgatggatc ggcagatggt
    18301 agtcgtcgaa acaacgcata atatcagcaa aagtagtgga agaattaaag attgcctgat
    18361 tctcgtcacc tactaaagta aagtgagttt ttggaaataa ttcgatcaat agacctaatt
    18421 gtgccagggt ataatcttgt acttcatcaa tcaatagata gcgaaatgct ggtacattta
    18481 ccttttcaac aagtaaatga cgaatagcta atataatgac tgcttcatca acagtacgtg
    18541 tgggttgcca agcataagct gagccatatc gtttttcata aattctttca aacaactgat
    18601 gctcatccac ccatgccatt tcttcgattt gtctggttat ttttcgatat tttttttgta
    18661 aaagtttcct tgcataagct acaatacttt gttccgaatc atcagaaatc aatttaccga
    18721 ataattccaa ctgcctatct tctgtcaacg agagtacctg attctgcaca gcaggacttt
    18781 ttgcttgttt caaaagatga ttcttccatt cgctcatcag tgcctttttc gttgcttgaa
    18841 gcctatcgat caatttagga tgagcaggaa ctttctcata tattttttcg atcgtttttt
    18901 tagaaaggac tgtttttcca tttttagtaa gtccacggat aaaattcgga tgatctaaaa
    18961 acaaaggatc tgattgtttt agattatcga taaacttttt gctacgcaaa cgttctgtct
    19021 gctccgatac attttctccc gtgatacgtt tgaaataagc ctcttcacct tctatttcct
    19081 ctgctgaaag ctgtgaaacc agctgtatga tggttagatt cagtggattt ctttcaccta
    19141 atgatggtag gacattcgaa atatagtcga taaaccgatg attaggtgat agaatcagca
    19201 agtcatcgga tgtcatcgta tctcgatata aatagagcag atacgcaata cgctgcatga
    19261 tagcagaggt tttaccactt cctgctacgc catttaccaa gatattttga cttttcacat
    19321 cccgaatgat tgtgttttgt tccgattgga tcgtagcagt gatagccttc atttcattgg
    19381 tctcatcttg gcctaagact tctaataata cgtcatcttg aatagctaca gacgtatcaa
    19441 aaaacttgac caaacgatct ctttccaaaa gaaattgtcg tctttcttta ataaccgtat
    19501 cgattttatt ttgacgaacc gtataagaag atggaccaat catgttattg taaaaaagtt
    19561 cggcaattgg tgaacgccaa tcataaacaa gattttcatc tgcatcatct gtgaaatttg
    19621 ctgtaccgat ataaaaggat tcttttggct cattatccag aaagtctaca acgacttttc
    19681 caaagtaggg acttttcaat aaacgttcga tctttgctag ctgattttct gcgtttttct
    19741 gtttgatatt catctgatcg atttctctat ttttcatttc aatcatcgaa aaagtatcca
    19801 ggttatctaa gtaactgtca aaattcaatc gaagctcgcc agccatttct ttcaacgact
    19861 ggtttccttc tatttttgcc gtatccatcg attcccgcag ttcgtttttt ttatcaatta
    19921 gcttttgata cacgttcttc agatatgctt cttctaactg tttttgtgtg ttgaccatac
    19981 acattctcct ctttttttaa agtggtggaa ccgattagtt tacctctttt aagagtcgaa
    20041 tgcaagcttt ttaacgagta tcatttgtta ggatatatca gttcttcagg tcggacagtt
    20101 tgatataaag aaaatgcacc atcaaggttt tttacgtggt agccagactg cttcaagatt
    20161 ctttccgcta gatagctacg taatccgcta tgacagctga cgatatattc ttgttggctg
    20221 tctaattcat ttaatcggtc ccgaagttca ttcaaaggga tatgtttggc ttccttgaat
    20281 ttgccctttt ccaattcttc tgctgttcgc acatctaata aaatttttcc ttttgctagt
    20341 tctgtcggca attcatgcca ttgtacggtt tcactaagcc cttctgcaat gttcattgct
    20401 gcatatccta gcatgtttac tggatctttg gctgagccaa atggcggtgc atacgtcaat
    20461 tctaattccg gtaaatcgaa gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg
    20521 atccgtttat ccacaccttt tgccccaaca ccttgtgcac cataaatctc gccagtctct
    20581 ggatggaaga tcaacttcag taaaatatct gttgcttctg gataatagct tgcatgatct
    20641 tttcctgata catgaatgac ttcaaaagac agttcgtttt ctttggctgt tctttcactt
    20701 aaaccggtgg atgcggcagt cattccaaac gttcgtataa ttgctgttcc aataccgcct
    20761 tgatttcttc gagaaattcc ggaaatcgtg tccgcaactt gtctaccttg acgattggct
    20821 ggtgaagcaa gagaaataag tgcatctttt ccagtgattt gctgttttac aacgatagca
    20881 tcccccaccg cataaatatc aggaatattc gtttgataac gttcgtctac taggataccc
    20941 ccgcgtatgc ctaattcgat tccagcggtc actgctagct ggttatcagg acgaacacca
    21001 atggataaaa taactaaatc agcagggatg gtacgcccat catccagtcg caatcgtttc
    21061 ccgtggtctt caaatccagc gacagcatga gaagtaatca cttctactcc ttgatgagac
    21121 aattcttttt ctataaaagc tgccatttct tcatccagtg ttggaagaat atgtggtgct
    21181 tgttcgatca ccatgacttc taaacctctt ctttttaggt tttctgccat ttccaatccg
    21241 atgaatcctg caccaacgat cacggcacgc tttggctgtt tttctaatgc atgcatcact
    21301 ttatcgatat ctggtacatt tctaatagaa aaaacattgt cggcttctgt tatccctgga
    21361 atcgatggaa caactggttt tgcaccagga gataaaacca atgcatcgta ctgttcaatg
    21421 tgtttttgac cctcatgtac gacttctacc gttttgtttt cgggaaagat ggctgtcact
    21481 tcatgatttg gacgcacatc taaacaaaaa cgagcggata atgattctgg cgtttggaca
    21541 agaagatttt cccgttcact gatttctccc gaaagataat aaggcaagcc gcaatttgca
    21601 aaagaaacat acggtccttt ttcaaaaaca acgatttctg catcttccat taatcggcga
    21661 agccgtgtag cagcagacat tccacctgct acacctccga caataacgat tttcatctta
    21721 tttccctcct actgttcgat caaaccattg attcatgcca ccacgtacat tcactacatc
    21781 ataaccagat ttctttaatt ctttagctgc ttgtttactc ctcatccctg attgacaaat
    21841 cacatagacg gtcttttctt tgtctccatc atatctgttt atactttgta atggaacatt
    21901 tttagctcct tttatatgcc cgccccggta ttctgcaggt gttctaacat caagtaacgc
    21961 tggattttcc aaaagctttt cctttaattc tgggactgtt atcgatttta ttgattgaaa
    22021 tagcaaattc attttctgca cctcatttac atttttataa atacctcatg gggtatatta
    22081 aacaggagct ttattaatat gtcaaccaga atgactcttc atttttttca ctacttttta
    22141 tatttgcata aaataccgat aaggggtatt atctaattat aaaaatagag gagaatgtgt
    22201 tatggagatt gataataaaa atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg
    22261 tggtatccaa aaaatgatcg aagacgaaaa agaatgtatg gatgtcatca ctcaattaag
    22321 cgctgttcgt tctagtattg atcgcgtaat gggcatgatc gttgcagata atctgaaaaa
    22381 ttgctttgag aaacctgata gtaatccaga agaacaagcg gctaaactag aacaagcgat
    22441 caagatgatt attaaaaagt aaaggaatga tttcaatgaa agtcgttttc catattgatg
    22501 aattagaaaa atggtcagaa acagggaaaa acgtaaaaaa cctgataaaa gcttctccag
    22561 aaacgacgat tgtcgtatct gtaaatggca tcgcgattac cggttatcta gactctgcca
    22621 atgcagaatt cttagatttg caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg
    22681 ctaatcatat ttcagaaagt tctttacctg aacaagtaat cgttgtacca gcaggtgtcc
    22741 ttgatttagt tgaactgcaa tcccaaggtt atgcttatat caagccttag tcagtagagg
    22801 ttgcgacaga agtgatcagc ttcaagaaat ttcggcttat ttttcgaaga agctacttct
    22861 ggaaaaccgt gaatcaaagg ttgtgaaaac gctgtcctgc atcaagtaat aagaacagcc
    22921 aaacaaaaat agcttctcat atttttcgtt tggttgggct tattaccgca gatgcaagct
//
LOCUS       DBBGRF010000047        22430 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000047 DBBGRF010000000
VERSION     DBBGRF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.047"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            134..532
                     /locus_tag="ACIZD4_002091"
     CDS             134..532
                     /locus_tag="ACIZD4_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HGC5990997.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            516..1211
                     /locus_tag="ACIZD4_002092"
     CDS             516..1211
                     /locus_tag="ACIZD4_002092"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGC5990998.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1805..2692)
                     /locus_tag="ACIZD4_002093"
     CDS             complement(1805..2692)
                     /locus_tag="ACIZD4_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HGC5990999.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2877..3716
                     /locus_tag="ACIZD4_002094"
     CDS             2877..3716
                     /locus_tag="ACIZD4_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGC5991000.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3912..4886
                     /gene="sgrA"
                     /locus_tag="ACIZD4_002095"
     CDS             3912..4886
                     /gene="sgrA"
                     /locus_tag="ACIZD4_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HGC5991001.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5184..5540
                     /locus_tag="ACIZD4_002096"
     CDS             5184..5540
                     /locus_tag="ACIZD4_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991002.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5585..6700
                     /locus_tag="ACIZD4_002097"
     CDS             5585..6700
                     /locus_tag="ACIZD4_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991003.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6726..7166)
                     /locus_tag="ACIZD4_002098"
     CDS             complement(6726..7166)
                     /locus_tag="ACIZD4_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC5991004.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7326..7832
                     /locus_tag="ACIZD4_002099"
     CDS             7326..7832
                     /locus_tag="ACIZD4_002099"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGC5991005.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8000..9913
                     /locus_tag="ACIZD4_002100"
     CDS             8000..9913
                     /locus_tag="ACIZD4_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC5991006.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9918..10919
                     /locus_tag="ACIZD4_002101"
     CDS             9918..10919
                     /locus_tag="ACIZD4_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC5991007.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11121..11327)
                     /locus_tag="ACIZD4_002102"
     CDS             complement(11121..11327)
                     /locus_tag="ACIZD4_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HGC5991008.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11973..12821)
                     /locus_tag="ACIZD4_002103"
     CDS             complement(11973..12821)
                     /locus_tag="ACIZD4_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC5991009.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12985..13887
                     /gene="gnd"
                     /locus_tag="ACIZD4_002104"
     CDS             12985..13887
                     /gene="gnd"
                     /locus_tag="ACIZD4_002104"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HGC5991010.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13889..14890
                     /locus_tag="ACIZD4_002105"
     CDS             13889..14890
                     /locus_tag="ACIZD4_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HGC5991011.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14887..15171
                     /locus_tag="ACIZD4_002106"
     CDS             14887..15171
                     /locus_tag="ACIZD4_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HGC5991012.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15204..16001
                     /locus_tag="ACIZD4_002107"
     CDS             15204..16001
                     /locus_tag="ACIZD4_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HGC5991013.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16015..16848
                     /locus_tag="ACIZD4_002108"
     CDS             16015..16848
                     /locus_tag="ACIZD4_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC5991014.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16866..17723
                     /locus_tag="ACIZD4_002109"
     CDS             16866..17723
                     /locus_tag="ACIZD4_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC5991015.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17745..18254
                     /locus_tag="ACIZD4_002110"
     CDS             17745..18254
                     /locus_tag="ACIZD4_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HGC5991016.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18291..18692
                     /locus_tag="ACIZD4_002111"
     CDS             18291..18692
                     /locus_tag="ACIZD4_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991017.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18804..19157
                     /locus_tag="ACIZD4_002112"
     CDS             18804..19157
                     /locus_tag="ACIZD4_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991018.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19191..19634
                     /locus_tag="ACIZD4_002113"
     CDS             19191..19634
                     /locus_tag="ACIZD4_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC5991019.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19651..20736
                     /gene="uxuA"
                     /locus_tag="ACIZD4_002114"
     CDS             19651..20736
                     /gene="uxuA"
                     /locus_tag="ACIZD4_002114"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HGC5991020.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20729..21442
                     /locus_tag="ACIZD4_002115"
     CDS             20729..21442
                     /locus_tag="ACIZD4_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC5991021.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21649..21798)
                     /locus_tag="ACIZD4_002116"
     CDS             complement(21649..21798)
                     /locus_tag="ACIZD4_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991022.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22194..22394
                     /locus_tag="ACIZD4_002117"
     CDS             22194..22394
                     /locus_tag="ACIZD4_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC5991023.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7737 a         3444 c         4638 g         6611 t
ORIGIN      
        1 cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat gtgttattca
       61 ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg atattttacg
      121 aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta tagaagcaga
      181 agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg aaacattaac
      241 agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt gtgatatgaa
      301 gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg tccaaactaa
      361 tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc cggaacttcc
      421 aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga caatcattaa
      481 aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt gatacagcaa
      541 atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta acaacaaatc
      601 ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa gaaatcaaaa
      661 aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa gaagaaatga
      721 tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc aaggtgccgg
      781 tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat ttgattaccg
      841 gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga gcagattata
      901 ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa gtgattgatt
      961 cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca gctagtttca
     1021 aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata acgttaggta
     1081 aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg aggggcttcc
     1141 aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa aaggtcgctg
     1201 attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa actcgaggag
     1261 gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac taactattac
     1321 ttatttctca tttaaacgat gtattcccta acctctaata catccttgta actctgaagt
     1381 tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata aaaatatctt
     1441 tcgtgtttct ctagtataac agaataagaa gaacaagtcc agaagggata tttttagtct
     1501 tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg aagcgatacg
     1561 gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg attcatgtga
     1621 tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc agtgatttgt
     1681 tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt gcctcaaaaa
     1741 taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat tgggtcaaat
     1801 ttgtttattt gaatatattt tttacataag gatctttaat agttacattg tcttttttca
     1861 tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct tcggtagcaa
     1921 ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt ttttttacca
     1981 tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga atgatatcag
     2041 aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga atctctggat
     2101 tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt tttccataag
     2161 cttgaacaag cttggagaaa ttttctcctt catttgcttc tttttttgct ttatctgctt
     2221 cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat tctttccaag
     2281 cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat tggaaagcca
     2341 gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct tttaattgtt
     2401 ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt acttcctttg
     2461 aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt ttttttaata
     2521 gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact gtaagtgttc
     2581 cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat agtaaaattg
     2641 cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc atcctttcct
     2701 tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg taaggttgct
     2761 gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat ttacatagtt
     2821 ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga tgaaagatga
     2881 tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt gttttaggaa
     2941 ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg attggagcaa
     3001 ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt gctagtaagg
     3061 tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac tgggggtatt
     3121 tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt ccattatatt
     3181 tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg ataacgagtt
     3241 ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc ttttttcagc
     3301 atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca ttatttgctc
     3361 ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc tttttagcag
     3421 gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct attggtgctc
     3481 atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc ggaacgcaag
     3541 aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact gggggaaact
     3601 ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt gttggtttgt
     3661 tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat caataaaaga
     3721 tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga ttaaacgaaa
     3781 aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca actgactgtc
     3841 gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta attatatgga
     3901 gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg ctgagtataa
     3961 ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag aatctttcat
     4021 ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt actattccag
     4081 tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca tatggttggg
     4141 atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac gtacaatgga
     4201 ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat gagatcaaga
     4261 gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc acggagaatt
     4321 tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc acaagtagtg
     4381 aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc agtgaaagta
     4441 gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa agtagcacag
     4501 gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc acaggaagca
     4561 tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga aaagtaaata
     4621 atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat gcagggagca
     4681 acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat catcaagaaa
     4741 aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt agaaccttga
     4801 acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca agctattttc
     4861 gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa ttgaataaaa
     4921 cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc gaagttgtag
     4981 ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata acaggaacac
     5041 aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta gtatctctga
     5101 aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata agtctaaata
     5161 atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat gaaaggcaag
     5221 tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg gtgaaggata
     5281 tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa caagcagaat
     5341 cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac aagatgataa
     5401 aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt ttagagggaa
     5461 cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc ttagaaaatc
     5521 ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag aacttaatac
     5581 tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga tagaaggaga
     5641 agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg acgaaaatca
     5701 ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat ttgcgaaaca
     5761 tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa gaatttcgtt
     5821 gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga acaaatttgt
     5881 gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt tttttgaagc
     5941 aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt attttatgtt
     6001 tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata aagtacaaga
     6061 aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact tcaagatttg
     6121 ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc atttgtattc
     6181 aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag aagacagaga
     6241 ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta gtggggtagc
     6301 tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga tttttcaata
     6361 ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat tctatattca
     6421 atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat ctatgactga
     6481 acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca ttagcgatta
     6541 tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact ggaatggaca
     6601 acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca ggaatgagaa
     6661 aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga ttgtttatgc
     6721 caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg accagaaagc
     6781 aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct gattttatct
     6841 tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt tttcaataaa
     6901 gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc tattctgtga
     6961 acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc gttgtttgtc
     7021 aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa gttctgttcg
     7081 ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga cgagcagcca
     7141 gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt tatgaaataa
     7201 taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa aatgttgtca
     7261 cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag aaagaaggca
     7321 caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa ggggtatgtt
     7381 ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat aaaagaatca
     7441 aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat gctcaattag
     7501 tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag cacagttatt
     7561 ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt ttattaactg
     7621 aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt atagatacga
     7681 ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga gcaacgacaa
     7741 cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag aaaatttggg
     7801 ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa aaaagcagaa
     7861 tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat cctgttctat
     7921 ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac atataattct
     7981 cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa agggagcgtt
     8041 ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg gagagagcat
     8101 ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg ctggaaatga
     8161 aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg agacatctgt
     8221 tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag aagaagcaac
     8281 agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca aagagaatgg
     8341 gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat atttgaatta
     8401 cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca agtcaaaatt
     8461 aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata aagagattat
     8521 caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa acagtgtgtt
     8581 gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca caggcttcta
     8641 tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca aaatgatgga
     8701 tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc atggcggatt
     8761 tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt ataaggccgg
     8821 gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg attatgtgac
     8881 ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag ttcgagagcg
     8941 gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga tgatgtctgt
     9001 attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg gatttgcatc
     9061 aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac taccggatgc
     9121 cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat ttatgggcct
     9181 tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg ctctacctac
     9241 gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag atgatgtagt
     9301 acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag atcttttatt
     9361 agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct acacgaaaca
     9421 tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt atgtggatga
     9481 aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag cttatggaga
     9541 aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg ttgaaggacc
     9601 gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca aaaaaatccc
     9661 agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg gaaagaatga
     9721 acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag tgaaagtaca
     9781 aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct
     9841 tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag
     9901 aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca
     9961 tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct
    10021 tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg
    10081 atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt
    10141 acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc
    10201 ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt
    10261 tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac
    10321 cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa
    10381 aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg
    10441 cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc
    10501 atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt
    10561 tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat
    10621 gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag
    10681 ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa
    10741 atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag
    10801 tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt
    10861 tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa
    10921 gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt
    10981 tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga
    11041 tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc
    11101 ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat
    11161 ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt
    11221 tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa
    11281 atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc
    11341 ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga
    11401 tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa
    11461 tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa
    11521 atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg
    11581 atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca
    11641 aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa
    11701 aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa
    11761 ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca
    11821 atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct
    11881 gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt
    11941 tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt
    12001 cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat
    12061 agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct
    12121 gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct
    12181 tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt
    12241 gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa
    12301 gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc
    12361 aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag
    12421 acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac
    12481 ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc
    12541 tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg
    12601 atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga
    12661 aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt
    12721 actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg
    12781 ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat
    12841 aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa
    12901 aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag
    12961 ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga
    13021 ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca
    13081 agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa
    13141 tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata
    13201 accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa
    13261 ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa
    13321 atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc
    13381 ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta
    13441 gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg
    13501 atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta
    13561 caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg
    13621 gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta
    13681 agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg
    13741 ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca
    13801 caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga
    13861 catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc
    13921 cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt
    13981 tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg
    14041 attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa
    14101 agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc
    14161 agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac gaaatgctgt
    14221 agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc
    14281 aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa
    14341 caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg
    14401 taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga
    14461 aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg
    14521 tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca
    14581 gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc
    14641 gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga
    14701 agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca
    14761 tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt
    14821 cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat
    14881 aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat
    14941 ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa
    15001 agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt
    15061 ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct
    15121 gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg
    15181 gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg
    15241 gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata
    15301 aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta
    15361 taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag
    15421 atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg
    15481 aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc
    15541 attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc
    15601 tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa
    15661 gaaatgtggc agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc
    15721 gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc
    15781 gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc
    15841 tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg gctgaattta
    15901 ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac
    15961 agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa
    16021 acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc
    16081 tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc
    16141 gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg
    16201 atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca
    16261 gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt
    16321 gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact
    16381 tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga
    16441 tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt
    16501 gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc
    16561 gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact
    16621 gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt
    16681 gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc
    16741 gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac
    16801 aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat
    16861 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
    16921 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
    16981 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
    17041 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
    17101 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag
    17161 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
    17221 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
    17281 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
    17341 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
    17401 tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag acagcgattg
    17461 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
    17521 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
    17581 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
    17641 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
    17701 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
    17761 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
    17821 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
    17881 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
    17941 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
    18001 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
    18061 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
    18121 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
    18181 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
    18241 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
    18301 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
    18361 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
    18421 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
    18481 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
    18541 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
    18601 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
    18661 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
    18721 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
    18781 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
    18841 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
    18901 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
    18961 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
    19021 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
    19081 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
    19141 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
    19201 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
    19261 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
    19321 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
    19381 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
    19441 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
    19501 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
    19561 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
    19621 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
    19681 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
    19741 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
    19801 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
    19861 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
    19921 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
    19981 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
    20041 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
    20101 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
    20161 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
    20221 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
    20281 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
    20341 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
    20401 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
    20461 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
    20521 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
    20581 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
    20641 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
    20701 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
    20761 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
    20821 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
    20881 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
    20941 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
    21001 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
    21061 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
    21121 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
    21181 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
    21241 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
    21301 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
    21361 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
    21421 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
    21481 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
    21541 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
    21601 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt
    21661 ttttaattct tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc
    21721 tttgtcaaaa acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc
    21781 tttgttatag aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa
    21841 cgcgttgata acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta
    21901 agaaatttta aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa
    21961 tcaatcgcgg ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaaattta
    22021 tatttcattg cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct
    22081 attttgaaac gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa
    22141 tatttattgc aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata
    22201 acggtacagt aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg
    22261 gaaatgatgt atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag
    22321 aaggccaagc agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca
    22381 ttgttaaagc ttaataaaaa ttgactttta accgtctttt cgaaagaaaa
//
LOCUS       DBBGRF010000048        22170 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000048 DBBGRF010000000
VERSION     DBBGRF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.048"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..329)
                     /locus_tag="ACIZD4_002118"
     CDS             complement(<1..329)
                     /locus_tag="ACIZD4_002118"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991024.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(343..600)
                     /locus_tag="ACIZD4_002119"
     CDS             complement(343..600)
                     /locus_tag="ACIZD4_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991025.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(795..1337)
                     /locus_tag="ACIZD4_002120"
     CDS             complement(795..1337)
                     /locus_tag="ACIZD4_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HGC5991026.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(1358..2449)
                     /locus_tag="ACIZD4_002121"
     CDS             complement(1358..2449)
                     /locus_tag="ACIZD4_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC5991027.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(2457..4667)
                     /locus_tag="ACIZD4_002122"
     CDS             complement(2457..4667)
                     /locus_tag="ACIZD4_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HGC5991028.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(4683..7211)
                     /locus_tag="ACIZD4_002123"
     CDS             complement(4683..7211)
                     /locus_tag="ACIZD4_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5991029.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(7263..7673)
                     /locus_tag="ACIZD4_002124"
     CDS             complement(7263..7673)
                     /locus_tag="ACIZD4_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HGC5991030.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(7686..7904)
                     /locus_tag="ACIZD4_002125"
     CDS             complement(7686..7904)
                     /locus_tag="ACIZD4_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpD family membrane protein"
                     /protein_id="HGC5991031.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(7901..8893)
                     /locus_tag="ACIZD4_002126"
     CDS             complement(7901..8893)
                     /locus_tag="ACIZD4_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC5991032.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(8972..9883)
                     /locus_tag="ACIZD4_002127"
     CDS             complement(8972..9883)
                     /locus_tag="ACIZD4_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGC5991033.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(9902..10246)
                     /locus_tag="ACIZD4_002128"
     CDS             complement(9902..10246)
                     /locus_tag="ACIZD4_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991034.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(10266..10544)
                     /locus_tag="ACIZD4_002129"
     CDS             complement(10266..10544)
                     /locus_tag="ACIZD4_002129"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991035.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVMQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            complement(10903..11403)
                     /locus_tag="ACIZD4_002130"
     CDS             complement(10903..11403)
                     /locus_tag="ACIZD4_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991036.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(11404..11949)
                     /locus_tag="ACIZD4_002131"
     CDS             complement(11404..11949)
                     /locus_tag="ACIZD4_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991037.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(11946..13202)
                     /locus_tag="ACIZD4_002132"
     CDS             complement(11946..13202)
                     /locus_tag="ACIZD4_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC5991038.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(13563..13874)
                     /locus_tag="ACIZD4_002133"
     CDS             complement(13563..13874)
                     /locus_tag="ACIZD4_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991039.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(13897..15372)
                     /locus_tag="ACIZD4_002134"
     CDS             complement(13897..15372)
                     /locus_tag="ACIZD4_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HGC5991040.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(15821..16273)
                     /locus_tag="ACIZD4_002135"
     CDS             complement(15821..16273)
                     /locus_tag="ACIZD4_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991041.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(16275..16640)
                     /locus_tag="ACIZD4_002136"
     CDS             complement(16275..16640)
                     /locus_tag="ACIZD4_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991042.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(16739..21022)
                     /locus_tag="ACIZD4_002137"
     CDS             complement(16739..21022)
                     /locus_tag="ACIZD4_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HGC5991043.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(21169..21408)
                     /locus_tag="ACIZD4_002138"
     CDS             complement(21169..21408)
                     /locus_tag="ACIZD4_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991044.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(21498..21740)
                     /locus_tag="ACIZD4_002139"
                     /pseudo
     CDS             complement(21498..21740)
                     /locus_tag="ACIZD4_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21853..22104)
                     /locus_tag="ACIZD4_002140"
     CDS             complement(21853..22104)
                     /locus_tag="ACIZD4_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991045.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
BASE COUNT         6478 a         4804 c         3308 g         7580 t
ORIGIN      
        1 gaattcattc cccaaaggcc ttttaagatt gatacagcag tccgttcact tcttttagac
       61 ttgtcataca agtcttttaa atgatcccat atcagactag tttgtctatc tagcttcaat
      121 ccattaaacg ctaatgaacg gttcattttt tctattactt tagataaagc tacagaaatt
      181 tttatacctt cacaacgcgc atcttggatt tcaataatag tatcatcaat tagtttttga
      241 atttcttgcc tatcaacata ttcaatctta gaaagagaat cttttaaagc tactaatgat
      301 tcaacgattt cttttttctc ttcagacatt ttcttcctcc ttctagtgac ccgtaaagcc
      361 atgtagagca gagtccattg aaccagtaat tacactatct acaacgccat tccaatttac
      421 tctacatttt ccatttttca gatttgtcgg tccatacgga tagccttttt gacattcaat
      481 gttcggatta taccagatag gattatacca ttcagccgca gaagcagatt cagtcgatac
      541 aaacaatccc acaccaacaa atccaataca catcacacta tagccaatta gttttttcat
      601 ctcgtatcca tctcctaaaa aatagaatag ttcttatagt tattcataag acatattttt
      661 tccgtttttg ttttatcctt tctgtcctat aacaactttt ttcaagtaaa gaatgacata
      721 gtttttctta aaaaaacagt ctgttttttt ctatttcttc ggtgtataat aaatatgagt
      781 gttcattttt tattttaata cgcactccgt acataataaa tcttgatcgc atcaatcttt
      841 tgagcttctt gatctacttt caattgaagt aatacaaatt gagtaacctt attcattgtt
      901 tcttctccaa ataacaaata ttgatccgga ttctctatat cttgtgtcac ctggtaaagt
      961 ttcccagttg ttttcatttg tacatgcggg tctacatcaa tactattgtc tttaatacaa
     1021 cgatctgtca tatagtccct cacagcttga ttgcgtttat aaacatctgt gaaattactc
     1081 cattttctag caaaatcttt taagaaattt tttgtcattt catctatttg catttgttgc
     1141 gctgtctcgt cttctaatga accaatttga ctgttacttt cagtactttg aagagttcca
     1201 cttgtttctt ttactgcttc gattgtttct tctgtcgttc tcaattgtgt tttttgtttt
     1261 tcagaagaaa accaatgaca accagtaaga cctatcaaac ataaccaact aaatactaaa
     1321 attatccctt ttttcacgtt tctagtcact gcctttctta tttcacctta cgaaccagac
     1381 tacgaatttt tgtttgattg tacgtgcgtt gataccgagc cataatccgt ccttgctcgg
     1441 cattctgttc cacactagag aaatgttgtc cgccatatga aacatctgtt ataattccgg
     1501 tgtgaccata gattccagga gacaatgcac cacctgcttg ccaattcacc acatctcctg
     1561 cttgtaaatc acttggtttt gggttcatga ttacttgcca accataggtt gtccagttat
     1621 aatcttcccc tattaacatc gcaaacatgt gtccagaacc cattaactgt gggccaccta
     1681 attgagatac ataccatgcc gtaccaccat aacattcccc attatttacg gatcgtccaa
     1741 tgatccgatc caaaaccttc gcattgcctt tactttttcc tgcaataagc gaagtttttt
     1801 ttgttggtag gctattccaa tgcttgatcg caaaagtatc atattccgtt aagttatagg
     1861 acgttatgat actcattgct cctcgataat acggactccc ttcggtaata cctgctgccg
     1921 catagcctcc acgacctaga atcaataaac aacttccagg atctttattg cccacacatt
     1981 gattaaagtt gctttggctc gccaccataa agccataata gtcataacaa gcttttaagt
     2041 tcggaaactt catatagaaa ccaccttcag aaccaccaat tccacgtgca gaaccttgtg
     2101 ggtagggaca accaggaaac caggtaatcc caaaaaagtt cgtatcgttt cttccagatt
     2161 gtgactgtcc ataagctgat tcatagccta attgagaaag aatcacactc ggtaataact
     2221 gatactttac agctgcacca actgctgctt gcgcatgttc atctgtgatt ggaccacgtc
     2281 ctttaatctc tgaaaaaatc ggtaatcctt cggtatattc cccattaaaa gcgacagcta
     2341 gacctgtagc ttctcctcca tgctcagaaa gttctcctga aaaaaagaat ggcaatagaa
     2401 aaaagggaag aataaagaaa agaagacaac ctagacaccc tttcttcatt tcttcctcat
     2461 cctttcttcg ataatggttt ttggactgtt cgtccttttg gtaaagtaaa atcagttcct
     2521 ggttttgcgt ccaaaatcgg cagtgtttta ggatcctttt ctattttttc cgattgctct
     2581 gttggcttat ctaaagaaga aaatgcaggt tgtaacgatt ttggtgcgga aatcgacggt
     2641 ttactttcag acgaacgttg ccccggttgt tgcacagaac gatttcctga tagagtggct
     2701 accgacgaat taggaacaga gtattggttc aataactgct gcattgctgg ataactccca
     2761 tttttcgcct gatttttcac ttggcgaatc tgttgtgaaa gagaaccagc agctgttaat
     2821 tgtggcacgg gtacttttcc agaaggcaac ggaatcgatt gaccaacaaa agcgatacct
     2881 ttatttaaca atggttttct ttgattattc ccttgttgct tactcaattg tgccaatgat
     2941 tgtacctgtt gttttggtct tactgaattc atggacgaat ttggaatcaa accatttgaa
     3001 agaccagaat tccactctgt tttcgatttg gtagaagaca tttcaggctc taccccatga
     3061 taacgaacat gacgaccact ataaggcaag gcttgatttg aacgcccacc tagttcaaag
     3121 ggattaacca cttgcctccc ttttaccgat tcttgtggtg tacgtttttg ttgaaacttt
     3181 tgaaatccat gtatcgctgc agaagcgagt ggattcgttg ctcgatacac attccctgct
     3241 aatcctgcac ctttgattgc caaattttgt ccagcagttg atagttgacc aggcagttgt
     3301 ttcatttgag acaaagaatg acttgctatg tttttcgtgt tgtttatagt ttgatctgca
     3361 gctcctaacc ctagtttctt taataaatct ttccgtttta caatgagtaa aattgatagg
     3421 agtgctttga caaacatatt tcctaaaaaa ccaaaaacag tattcattgg aattaaatcg
     3481 tctactatgt tatagatcaa aaatgccacc aaaataatca cactgtaaaa agatttttga
     3541 aacatcaagc ccaaaaagga ctttaaggta ttcatgagca tataatcaaa tactggaaca
     3601 aaagaagcga gtaatgaaaa aggaatcaca agtaataaac acaacaccaa catttgaaag
     3661 ataaaacgaa tcatgccaat cactacaagt ggtaatccaa tacttagatt aagcaatggc
     3721 accatagaac caacgactgc tttataaaca gctttagttg gttgaatata gacacgataa
     3781 gccttctttt tccctctatc ttctcctgca gcagtggtca cttttgtctc aatatcagat
     3841 aattcttcac ttgacgcttc cttggctaga aattcttgtg gttcaatctc tgcttgatac
     3901 aattcttcta aatttgttgt cccataattt aacaatatat acggatcaac aacagccgct
     3961 ttataataaa gttggcgcac tttttgaatg gcttcctttt gtgtcgttgg cactaaaaca
     4021 ccattgacat cttttgtcgc caattcatct agactatttg tagcagaaaa aataaagcct
     4081 tctacctcca cggacaaatc atttaaccct ttggtaaaag cttctccttt actaggtacg
     4141 ttactaccat agccaaacca aaccattgaa aaaatgacaa cgaagagaaa tcgaataaac
     4201 accatttttg cgtaatgttt ccctctaaat atacgaagag taaatagata taacacatac
     4261 aagacgacaa tccccgcacc aataggatcg tatatttttg aataaatagt atccgaaaaa
     4321 gtgaaaaact ggtgaattaa ctcgttcatt gcagctcctt catagagctt ctcaatgaca
     4381 aaatcaaggc cttgccaaat caatttactt aaactaaaga acatattcgt catcattttt
     4441 agaaaatctg tgccatttgc cccaaataac attttgccta atgaaaattc actatcagat
     4501 aaataagaag aaaaggtatc aatatgaaat ttcccaatct catagatcga ttgatccacc
     4561 tgcttttctg ccgcatacac caatccacca acaaaaagca gtccgaatcc aatcgttaaa
     4621 aaaaacaaaa cgcaccattt cttttcctta tgctttatat aagccattgt ttcacctcat
     4681 ttctattgca tgattaacgt atcctgttct tctacttgag agtgacttgt tttttccgtt
     4741 gtttgtaatg cagcggtcat ttcttcaaac aaactgtgta cattgagttt tcctacacgt
     4801 ccatagggat ctaacatcca acactgtcct ttaatcatgt ggctcatttc agctaagttc
     4861 gcttcattta cttccaaacg taaatgattc aaaatctttt ctcgctcact gtcttcatca
     4921 aaagcaaaga cgacaccaaa attccctttt tctttatctg aacctaagtc accaataaat
     4981 tgtgtatcta acactaattg attcatctgg gaacgcccca cacgtgccat tgctgcaata
     5041 atactacgtc ctgcgttcga attattaaat acccatgctt ctgtaaaata aatcgctgtt
     5101 ttcttactac tatctcgttt tccaaacatt tcacaaaaac gacctaaact aatcatcaaa
     5161 cacaaagact ttcgatccgc atctgtatat agttctggtc ggacattgtc atttggtaat
     5221 ttcaaatctt ggatctctaa aatcgttgtt ttggcattaa agtctaatcc cgggttttct
     5281 ccataagaaa atcctaaacg taaaatcgaa tcttctaccg tcaagcgtaa aaactcacca
     5341 tattctcgaa cctctttttg ttccatttgt tctaaatagt cgaccacatg catcaagcca
     5401 acttgttgtc cggcttcttt ttgaactaaa acttcttgga ttccctttaa taccgcccct
     5461 tttaaaaggt gattggtacc taacggactt aactcatcaa tcatatcctg ggctacttgt
     5521 ttcgcatcta ctcgggataa acaaacaatt ggatctaata caccataatt acggggattt
     5581 gtagcatcta acgtgacata actcattttt tgcaaatgtt ctacaaacaa agggtaatgt
     5641 ttctgataat acgggtcttg aatgagtttc gtaaaccatt tgcgcttttc tcctttggga
     5701 tccacaaata aactttgtac attcataaac gaactataca aaaagagcaa gccaactaaa
     5761 aaggtcttcc ctttaccggt ttttccagtt actgctacat gaggcgcatc aaacaacgca
     5821 cctttgattc cttccgcaat ggctagaaga ttcaaaaaga caaaacgatt tgacgcataa
     5881 attaattctt ctaatggtgt tttttctcct cgagaaccac catcccctaa tgtatcttgc
     5941 cgaccaatat accagccgga ttccatacct aattctgata ctgctgaaaa caaccattcg
     6001 ccaactgctt ctacagttgt tcggtgcttc caatgtaact gccgtcccaa tggttgccct
     6061 aataaacatt tatagaacaa ttctcgttga tcattttttg cacggtggat atggataatc
     6121 gtatgaagtt gttgaataac cgttgcacta ttttgacgaa cttcttcaac cgtttgaccg
     6181 tatacaataa aacatgcgat ccaatcgacg acaggttgcc cattatctac tcgttgcttt
     6241 aaatgtttta ctaatcctcg aacagttaat aagcgttcac taggttcttc atcattttga
     6301 accaattcct tatgctctgt tttgaaccgt tccgatagcc aattcagttt taaaccaata
     6361 cctccctgtc ctttcaagcg tggatagtga attttcattc gcaattctgc tgggaaagaa
     6421 agatcctgag caaattgaaa tagatcacaa tttctcatat tttcaggtgt ttccccaata
     6481 ggcaacaatg ctaaataact actccctaac tcatcttcta attgaagaag gcctttatgt
     6541 tccttcggta tacgtacata cgttccttga ttgtctttca gtacttccca attattttgt
     6601 tcttctactt tgtgagccat tcctcgaata tattgcagac gattgagata caacagctct
     6661 ttttttacta agggacgaat agaaaagcta taaagtaatt gtgtcacttc ttttacataa
     6721 ggatcacttt cagaaaacaa agtttccaaa tcatctactt ctaatccaaa taagcgtgct
     6781 aaacttcctg ctaaatctaa ccagattaga tttattacat catgaaaact ctccaccgtt
     6841 gctttttctt tgactttgat tcctaaaata aatgaaggac gatagacttg accttctcgt
     6901 tccaacaatg tcactgtttc ttttgcataa tacgcaccaa ttgcttgact atcgggagaa
     6961 aatccctttc ctaatgtgtc aaacttcgtc cgtaaattca ttgttcgtgg atacatcacc
     7021 aactccacat cttcataatc tgctaaaagc aacagtaaac gagccatcat ttcttttatt
     7081 tcctgtgtct tttttggtgt gttttttgaa attgttcgtg gaaaaacatg atagtaggcc
     7141 cagatacaat cctctccatt taacaaacaa tttttcttga atgcttttac tggttctttt
     7201 acaagcacca atgaatttca cctcccaata aaaaaggaac aaccagttga ttgtcccttt
     7261 ttctaatcct ctaaataaac atacttattc acaaaaagta attcttccaa tgcattgttt
     7321 gataccttgt cccagttata atacacacaa tcaccattca tcatacgaat catataacaa
     7381 aaccaatccc ataaataaaa atgcactttt tttccatcag gttttagttt tgccagtgct
     7441 aacacacata aataggggag tcctatataa aaaacaactc ctgctggtgg aaaaaaagaa
     7501 atgacccaac caataaatga acgtaaaaat aaatattcaa agattacgac caacaaaaaa
     7561 gttgctgcat tgactaatgc aactggaaat ggaagacgcc aattgcttgt aatctgttgt
     7621 acgcgataag gttccgcata aacaatcgaa taatcataag gttcccaatc cacttcacta
     7681 tcctcctaat ccataaataa tttttcaatg attttaccaa acgcatcaaa tacacgtgtt
     7741 ggatcattta agaagaaata aactgcggca cctgctgcga tagatattaa tgcatttcct
     7801 acttttgatt tcataaaatt tcgcaatccc agataaacaa ccaccattat taaaaaatag
     7861 ccaccttgcg ttaatataaa atctacaatt cccttcagtg tcatttccgt tcttctcctt
     7921 tcctatccaa ccaattatgt gttaattttt caacataata ctgatttgtt tttttcgtaa
     7981 tgacaatcgt catttgttct ttttgtaaaa gtgacgtatc accatctcga aagacgaccg
     8041 ttgcttttac aataaaaggt tttttcgttt ctttataacg caatactttc atctctactt
     8101 gatcaacttt agctgtttga ttgagtcctt caggttcttt catcatgtat gacatatctt
     8161 ttgcattgtt tttcgcatac ttatctaaga aatcttccac aaatccttca acatctttcg
     8221 cttccgacgc atcaaccgtt tcgtataatg tgtcatcata agtaatcatt cgttgttttt
     8281 ctgtattctt tggtagtgcc gtaaaataag gataagcaat aatacgacag cccttgtttg
     8341 aaatagaaaa gggaagattg agtacttgtg tgattgtcac acttgtttct ttcttactct
     8401 ctggattcat cgagcgaata tcataagtta ctttataact agcagttgga atggtttcaa
     8461 tttcttttaa tccaataaac gaagcagcag ttaattttcg aacacctgaa acacttcctg
     8521 gttcttgaat aaagttttgt gcataaaact ctttttttaa tgtttcttga cgttgttgtt
     8581 cttgttcatg attatcgaat gtattcatat acaaagcaac aaaacgattc ataaaggatt
     8641 caatttcagg tgtgtacgtt aattctgacc gactttgtac ttctttcttt tgtaattgtt
     8701 ggatttcatc tttcaaaaac gacacttgaa ccttcgtttt catggattga aaaaatgcca
     8761 agccccctga aaaacaaaga aataaaacca aacaccaaat ccatttcact gctttttttg
     8821 aatggatttt cttttgcttc ggtactttct ctgtataaac tttttctttc cgccgtagtt
     8881 gtcgtttttt cataagctac tccttctagt atgtttttac tagtacgtac gattgacaac
     8941 gataagcttg tttttctgaa aaatagtcca ttcaattacc ctcattttct attccttttc
     9001 tctttctttt atatccaaca aatccagcaa tacttgtcaa cactcctcct agaacagaaa
     9061 gtgcaacatg tatttcttca ccagtctttg gtaagacttt tgtttttcca tctgctgttt
     9121 tgatttcaat attgccactt ggaagtttct ttacaggaat cgacaaatcc tttaccaaat
     9181 tcccttcact atcttggatt aatggaatac catcttttac accaacaatt gtttgatcac
     9241 ctgctacttt taatggggtg gttggtgttg gaatatgggt caattcctct acattactag
     9301 tgacaatcgg tacactcatt ccttgagaag tattcgtcgt aatttcaccg cttggggtta
     9361 ccgatactgt gacttctttt gctggaacaa taggtttatt ttcttttgga attgcttctg
     9421 atttttcaac aggttgtttc ggttcttctt tttgttcttc actggtagac gacatcgttg
     9481 gctgttccgt acttgacgaa tcagtattct tttcagaaga actggttgtt cctgattgtt
     9541 ccggagttgt gactatactt gaatccgttg ttgttgaact atgcacacct tcttcttcga
     9601 tcgaatcagt cggtaaagtt gattcaggaa actctggttc tggtgtcact ggctcttttt
     9661 caggtttctc tgactgcaat tgttcaggtt ctgctggttt ttccgttgtt cctccattta
     9721 gctctgtctc aacatctggt aatccttccc ctggcaatgt ttctacaatt tctgacttag
     9781 gtgtttctac agtttcatct gcataaacca atgaactccc taattgaaac gaaaataatg
     9841 aaattcctag tgttgttacg actgctaatg ttgttttttt catgattatt cctccaattt
     9901 tttatgcaat tcgtgttttg ttcatagacg ccgcactaat attatctgaa cgataaaaga
     9961 actcccgtcc gttttcttct aacccaacat atggattatt tttgaataat tgaatcaata
    10021 gttcactggt gttgtatttt ggatagtttg caaaaaaata atactgtgct tgtcgcccat
    10081 ccgaaaattc aacaagtaat tcataacgat accgcttcaa tccttttcgt tgttttaaag
    10141 gatctctata ccaacttgtc catcgttcca ttcgtggata gagatagaca cgatacacat
    10201 agaacaatgc cataccacat accaccaaaa ataataatcg ccacataaaa attccccctt
    10261 ttcttctacc tttcttgaat catcgaacat tcataccctc tatagagatt tgaaaaatcc
    10321 atcatcaatt gttcatataa acgttgttgc aaatagcgat tgtttcgaat acataattct
    10381 tcatagccat caatcacttg atcttctttt tcatagcatc ttgtagctct atgacgctca
    10441 gcttgcatga cataaccaaa ctctgcacca tatcgttcta ctgttaataa ctgttgacta
    10501 cgcaataatg caatataaca atcacaaaaa tgttcaaccg acatttgatt tttctcacgt
    10561 ttgtgaaata ggtattcttt agaaagcaca ttattcgtta aacaatctga taaatagcga
    10621 taatctggcg gtcggttatt ttcatctgtg aatttttccc ataataaact gatttttatt
    10681 cgttcagcgg ctagatagtc ttgttcgcgt ggataaaatt catcaatcgc acaaagtttt
    10741 ttatcacctg aataaacaaa tccatataat gcgaaacgaa ctcttccttt tcaattggct
    10801 ctcctaaaaa ttccagtgac ataccatctt ctccttccta aaaaaaataa aaaagcagaa
    10861 accgatttgg cttctacttt tctttccttt tatagctctt ttttacggaa gaatccgcaa
    10921 atgacatttt ttcaaaaaat caatcggcac aagttcacga aaacttggag caattttgga
    10981 tagaatcact tccccatctt gtaaaataca atcataaaaa tcatcagtta cttgatactt
    11041 acgcttctta caataattga taaaatagta gcgatcattt tctatttcca ttcgttgttc
    11101 tactaagcgc atacgaacat catcatagaa ataagccaca aatcgccctt caagttcatg
    11161 tttttcaatg ggatactctt ctggtaacaa tctatttttt cgtcgtttat acattgctgg
    11221 ataccttaga agaagttcat ctaaacgtct gtcagtatat ggtaactgac gaatcaacga
    11281 ttctaatcgt tctttataca gatagaataa ttggcgcaag caatagtgta ccgcctctgg
    11341 attttctaat actgttggat cacgtgacca atacgcacca acataaatca taattttttt
    11401 catttagaca atcacaccag caatactaat gaccgatcca caataggtag aacaagtggc
    11461 atagcgacca atttcctcta attctatctc aatctcttct aaagaaagat atgtctgttc
    11521 ttctgttggc tggcgactca tttcccaagt gacagtcacc aatgaaattt cttccataag
    11581 aggtttttcg ctgctaagtg ctgccacaca gttttcatat atcttcattt tatcgcagcc
    11641 ttttttaacc gctaaaatcg caggtattgg caatgaaaat cgataaaagc gaatgaattc
    11701 tagccttcct ttccttcggc taaattccaa ctcttcgagt tcttgttcgt atcccttacg
    11761 aacttctaat aagcgtgcaa tttcttgcca gttctctttt tcctgataac gtccagcttt
    11821 taccgcttgt tcaatataag gaactcgaaa acgaaaataa gacaaatcaa ccatcttttc
    11881 atttaatgct tcgattgcag cctttaaatc caacaggcgc agccattctg ttgtcgtata
    11941 tgcattcatg caattttccc tcctgacgtt cccatccatt ctagatagtt ttgttgctcg
    12001 tcatttagtt cggcattatc aatcccttct tgtacaaagt ctcttcctaa aatacgatct
    12061 gcttcttgta acaactttaa tgtcggagct acttgtttca aaaaccagcg ttctgaacga
    12121 tctaatgaga atttttctgg ctttactgta aaatccaatt cttccatcga acgaaataat
    12181 tttgcccatc gtttatcaac aatccgtgca tcactttcca gtctatccca aacaataagt
    12241 tttgcattaa ttaaaccaac gccaatctct cctaaacgtt tcggtgaatc acctaaaata
    12301 aatgcttcta ctgcttgtgt tgctttctca ttggctaacc gtaactcata tcgattataa
    12361 ataccatatt tcgttaatgc ttctaattct gaaatttttt ctcggttcgc aatttcaaaa
    12421 cgtttctcat aaaaattaaa aaagagagga ctctttcgcg atccaaaata caaagataat
    12481 ccttcacttc gaaaatagcc atcatctaaa aaacaaccgc caatattctg gaatctctta
    12541 aagtccattt ctaataaacc tgctttttgt ttttctagta attcaaagag atcgaaatgt
    12601 tcttccgttt ccaatcccca aagttcatct aacgcaatat cgaatcggct acattgcaca
    12661 cgtgtataac cagcttccaa ctttccttga tttttccaaa tggaatatag ccatgttcgc
    12721 caatctgttt gttgttcacg catgacttcc tcatattccc ggcaaccttg tcctgaaaat
    12781 tgcacaagta cattttctgt tacagttcgt tttgaatgcc agaacaccca gatattccca
    12841 cgaacagaaa gacagtcaaa aagatacaag cccgttggac gtgtttcaaa ttctgtcaga
    12901 tccattcgta atacacgttg aatcactgtt ttgtagtctg tcccaaaaaa ggaaagacgc
    12961 aaataatcaa tcattgctcg aagatctatt ccgcttttca tatacaatcg aaagcgttcc
    13021 ttgattcgtt gttcaaaatc ctctgggatt tttcttttcc cttgttccat ctttctaatg
    13081 taatcttttg agcagcccat caattgcgca aatcttgctt gtgatagcgg ctttttatct
    13141 ccacttatat tatgaattgc acttaacttc tttctgtagc tttttagctc aatcggtgtc
    13201 attttctcgc tccttttata aaataacaaa atcgattttt tttaaccctt tagaaacacc
    13261 gatatatcaa ctagtccccc tcgttttttg ggaaaagtag tacaactgct gaccttagat
    13321 aatcacttga tacaaaaggg tttataaaac ttttttctat gtgttatgtt atttctgccc
    13381 cccatattat atatcggggg gctttacaca aagaggccgt gcgcaagcgc acgacctctt
    13441 tgtgagctgc acacgctgct agcgagtgcg cattataggc ccatgcttcg cagccttaat
    13501 gcgcaccgcc aggcagagtg cggctaccag actacgtcta gagccctccc gatagataat
    13561 aactacaaaa ttaaatgatc taattttgtt atttcactat atttttcagg agaaaaaacg
    13621 cgataaattg acaaagttaa atcctcttct aaatctactc gataatgata caatcgagtc
    13681 aatcgttcta tatctttttt cgttagcaat acttgattaa taacttttcc tgtaaaaaca
    13741 cgttctttgc gcaaaaagcg gtaatcagtt acttgttcaa tacgattcaa ccaatcataa
    13801 aacgttctgg aagaaagaga aggattaatc attcgtattg ctgtagctac tctataataa
    13861 caactctctg ccatttaact tcacctcctt agttgattac aaaatatgcg catcagaaaa
    13921 acttgttcct tttggatctt ttgctaaata catttggcgc tctagttgtt cttgtaacaa
    13981 ctgattatca tctcccatcg tttgatcttg actatcctct tttactgtaa aatcatagac
    14041 aatcatttca gtaaatttct caaattcttt gataaagtga taatctttgt aaacaaatgg
    14101 cgcaaaaaac tctacaggta catcaaatcc tggaaaagca tatccacgac caggttgatc
    14161 tttgttgtaa aatggcttat ttttaaaatc ttctccaaaa gtcattaaat aaccaatggg
    14221 agacaatcga ccaacagaaa tacggaatgt taaattatcc cgaacaccac ttggaaaata
    14281 ttctgcatct ggtcgttgca ttgctaaaat aatgtacatc cctgcttgac gaccctttaa
    14341 tactaatggc tgaatcaatt tatcgactct atttctcgct tccatatcca acgaaccata
    14401 aaaagctgcc cattcatcaa aaaagataaa atgcggtggt aacccataat aagcataatt
    14461 tttccctggt tcatatttag gatctttcat ggttttcata taggcatacc gttgattcat
    14521 ttcttttaat gcatttcgta aacaaataat catttcttca tttattttgt aaaacacatg
    14581 tcctttgaat acatcgacgt cacctaatgc tgctaaatct gccgcttttc catcgcaaat
    14641 atctactgtc ccaacactta aacaagcttg aattaaagaa tacaataaat aggttttccc
    14701 accaccgatt gcaccagcaa tcaacatatt tggtgattga tcatataccc aatccaaagt
    14761 tttcattaaa tgaatacgtc cattttctgc tatacattga tcaataggaa tccgaccaga
    14821 atctgaaagg aatacataat tgattcgggc tttttctcgt tcttcacgaa ttaaatcacg
    14881 caaaaatact tcagataaca aatgacccat ttttaaaaat cgttcgtgaa aacgcccacc
    14941 atctaaagga aaagaaacca ctaattcttg tttcttttga taaaaataaa cttttggtaa
    15001 tctcattttt tcccttgttt gtttctcact aacttgtttc tttgtataaa caaaccgatt
    15061 gtcaattaac attcgaacaa gtaactgacg ccaataaaca gaggcaaaat atccttcttt
    15121 tagtcgcgac caatgcatca accctaaaat taacccacta accagcaaca aatacaacac
    15181 aatacttatt ccaggaataa gatacatttg ccaattcgaa aacgtactta aacgtggata
    15241 aaatactttc caactaaacc aacctaacag aatcaaaaat ggaaacaaaa agaaaccata
    15301 atagcaaaac cataaataac gattgaaata gcgaattcgc cgaccacgat acttgaaaaa
    15361 atgagctttc aattgtcaca ttcctccttt ctgtttttac ttttcctgtg ctaaaaactt
    15421 ttgacaaaaa gcaactaata caggaatatc acatttagta aaaaaacata atcgaaaaag
    15481 atttaatcga tttttataag ggtgtgcaca catattacat attcgtacta tacgaatcca
    15541 aatcacttcc tgatgatctt gtttccactg gtacggtaat gaaaaacgaa caagatcacg
    15601 taaaaacata cactgcccaa taaccgcaca aatatatgca tttgtttgta caaaaatcgt
    15661 tggattgtct ccaaaatact caatcaattg ttggatattt tgataacaag cacaatctct
    15721 caaagtattt gattggtttt atctgaattc aaaatctccc cttccttcta tcttagataa
    15781 aaagaatagg aagactcctt cctattcttt caaaaaaacc ttattttttc tctttttcct
    15841 tagaatcaac acttggttgt ttttgatcta aacctttttc ttgtgattgt ttcatattag
    15901 gattatttgt tggagcttct actttctcta atcctttcgc ataaatcact aaatctgaat
    15961 attcacgatt gccatcttgt gctggaatat ataccacatg atattctgga tcaattaatt
    16021 tcacaggatc acgtcgttta aaaccagtca aatctacatc tgctggaaat ttaactcgtc
    16081 gtgcaatctt tggttcatct ggatttccaa aaactaattg tgctcgctgt gatcgaattt
    16141 ctcccgtata atcgcctgtt tcattatcaa atacacgatc agactcttct aatgcgccaa
    16201 agcgtacggc tcctaaacaa gtttcatcta atgcttctgt aatgtcataa ttatttggaa
    16261 attttaatcc catcttacaa aacctcccca atttttacac cagttaaaaa gacaccaaca
    16321 tcttgatagc cagttgttcg acgctctgtt tgtcccatat catttgtttc acgactattc
    16381 actcgttctt tacgaaaaac aaaataagct tcttcaaatg aaatacgcac ctctttttct
    16441 ggtaatcgta atcttttatc ctcttcagct gtgagataaa caaaaaaagc aggctgttct
    16501 tctcgcgaac actctgcttg taattgaaca tatcgcccag acacaccatt aatttccttt
    16561 ggtggattag gttcccgtga acccaataaa aatacttgac ctaaaaactc tttcttcata
    16621 cgcaatgctt tttctgccat aaagtttttc ctcctcttaa aaaccaaaat aaattctaaa
    16681 tatttctaca ttacaatcaa acaagcggtt aaaaatccta accgcttgtt cctcatgact
    16741 aatctttggc tttacgtact ttataaagtg ttatacctaa agcaatgact aatactacta
    16801 atccaagaac cataagtata ctacttgttt gttcacctgt ttttggcaac attggtacaa
    16861 cagtagctgg tttaacccgt tgttctggtt tcactggttg cggtggtttt ggcgcttcca
    16921 caatttgaac cgtttgatct ttgtttgtta gatctacatt gtgtttcgcc acttcttcaa
    16981 acgtttcttt ctcatcttcc gttttcgctt ggagccattc cgcaaaactc aagccttttc
    17041 ctgcaagatt gcgaccgtcc actaagaatt caaataagaa ttccatcatt tctttatcgg
    17101 ccgcaaagac tttttccgca tgagtgcctt caaatggtgt gccgtctggt gttaagtagc
    17161 cttgaacaat taagcgatag atttgaccaa tcgcaagacc gtctactttg acccattcaa
    17221 gcacagtttg atttggcaag gccaagatct cttttccgcc atttttattc gtcgctttcg
    17281 tcgtaatggt tggattactg attttgatgg tttggtcatt gtcggtaata tctgcgtgag
    17341 aagccaataa tacgccttct ctaaacagat cttcaaagac cacgacttct ttgcctcgca
    17401 acgcacgtgc gtctagaata aagtctagat tgactgtacc atccgttgtt tctgccacaa
    17461 acgttaaggt acttgtgact tcttttccat ctactagcac tggtttttcc gttactttgt
    17521 ccattagaac accgttgact gtgtatgttt ttccaacgac caaatcgtgg tatttcacag
    17581 cgtctgtaat ggtgactttc gttaatggat taacctcttt caagccagtg ggtttatgtg
    17641 tagccgttgt acgtacactt gggttagtta ctcgtaccgt ttgccctttg tcgttgatgt
    17701 ctttatggtt tgctagttct tcatcatttc taaaaagact ttcaaacacg acgatttcac
    17761 gaccatttat acctgtcaaa tcaaaggtaa atggtacgat caccgtttca ttttctgctt
    17821 tggcaataaa gccaacactc gtttctaccg tatttccatg cacaagcaag ggttcaccgg
    17881 ttgctttatc cattaagatc cctttgacca agtatgcttt tcctggaaga atctcggtaa
    17941 tttcaacggt atcgtttaag gtaaacaatc ctgttgggtc tgcgactgtc aatccgtctt
    18001 caaagacagc cgtggtatga acggttggat tattcacttt cacactttgg gcttcatcgt
    18061 tgatatccgc atgtgctgca acttcaatgc catcacggaa aagtttttca aaaacaacga
    18121 tcgtttgacc tttcagaaca ctagcattaa ccacaaattc aaggtctttt gtgccattga
    18181 ctttgtctgc aataaaggcc aaggtacttg tgatttcttt gccatcttgt aaaattggcg
    18241 cattcgttgc cttgttcatc aatactcctg aaatggtgta ttcttttccg acaaacaagt
    18301 tggtataaga aacactgtct ttaatgacga tcgtttctaa tggatcaacc actttttcac
    18361 catcggcttt atttgacgct tgtgtttcta gttttggtgg aatcaagtaa ttacgtacag
    18421 aaaccactaa cgtttcccca tcatctggcg cattttgttt gaatgcaacc gtgaatgctt
    18481 gtttatctgt atttggttgg aaactttcta atggggcatt ttccaagaag taatagtcat
    18541 cggcaactag acctttcact aaaatttccc cgttttgatc agtggtatat tcaccaattg
    18601 cttgattttt accgttatac aaggtaaagt tcacacctgc gagcggcgtt ttcttcttgt
    18661 tccattcttc atacttgaat aattttacac ttttccgtgc ttgacggttc gcaaaatgga
    18721 tcactttgat cggttctgta tcattggtaa tcgagaacac taatgggttt tgattcaaaa
    18781 cgtaatttac gggggctttg atttcttcca aacgatagcg atcttttcca taagtaagtg
    18841 taccgttagt taggaaaaag cctttttcat tggttttaaa gatatccgtt gtttctgtat
    18901 catttggaat ctccattgtg acataacgat tggctaaagt atcaaaaatc ttgaattctg
    18961 tattagcaag tggaatcact tttcctgttt cttgatccac tttcaccact ttaagacgtt
    19021 gttcaattac tttatcttct aaaacataat ggaaagtttg cccattttca gaaattgtga
    19081 cttcaagtgg ttcaaatagt ttataccctt cttttccttt ggtttcagaa agaatgtacg
    19141 tatcaaagac aacggtattt ttaccaaaag tagcataacc atcattgtct gtcacaacgg
    19201 ttttcaccac tttgccagtt gtttttgacg tcaaagtgat ttcaatgcca gctaattttg
    19261 gtttgttatc tggattcgtt gaatcgacta aatctttatt agcaactttc actaaatcaa
    19321 tggttccttt gatcacttga tcttttgcgg tcgcattgac agtttttcca ggttcaacaa
    19381 caatttcaat tgcttcatca gaaagcacat aaccttttgg cgctttgatt tcttttaaaa
    19441 catatttgcc aggatcaaga tctttaattt ctgcctgtac tttgccgtta atttttttca
    19501 aggtaatttc tttaatcttt ttcccatctg cttgatacaa accatagacc gcattttcta
    19561 aagaagctgc accttgtgct ttcacaccag tttccgcatc ttctttaaac acacgaatgt
    19621 ttccttgttt tagaatttgt aaattaataa cagacgcatt aggttctgtt ggatgtaaca
    19681 caccaattgt ttgagctcct ggacgacgat aggctaatgg cgcaccttga actttaattt
    19741 tattcaattg aatttttgct ttatccggtg cctcttttgt gactgtaatc catacttcat
    19801 tgccgtgaat agatacattg acaccttttg gtttttgaat gtctttcaca tatttcaaaa
    19861 aatcattttt attctttact ttcaacgttt cgccaatttt taccgtatgt gtttgattat
    19921 taaaagttgc tttttcacca aagttattaa tcaaacgttg aatttctgct tttcgacgat
    19981 cataatcaac acggatattt ttgattggga tttttgtgcc caaagcttcc caaatcataa
    20041 attgtgccgc aatgtattgt tcatcggatt tgtctttatt tgtgacatat cctaaataag
    20101 agatcaagct tgtttttttc cgtacatttg aatttttcaa atagtttttc aaagcagtag
    20161 ctgtataaac ttgaccttct gcggctgaga caccaggctc aatacaaaac gccacttgtc
    20221 cattaatctc aaaacgaacc atataattta aagtgaagtt tagattgttc ggactagaag
    20281 taacaccaat attttcgccc caatcaattt tccgaccacc taaaacagct gcattggttg
    20341 cacggcgaac acgaaccgaa cgattggttg gtactgttac taacagtgta ggtgtacctg
    20401 tttttggaat gttctgctct tttttctttt gattttcaat actagccgta gattctttgt
    20461 ttggtttcgt tggttgattt tgactagctg cggttgaaga gattgttttt tcaacgtttt
    20521 cctcattttt tccttctttg tcagcagtag ccgctggttg ttccactgtt tcttctattc
    20581 gtttcttttc ttccgcttgt ttctcagaag actctggctg cacagaaggc gttgcttcgg
    20641 cagctttttc tccttctaga gtggacgttt ctgaagcagg ggttgtaatt gaggcagttt
    20701 cttcaactgg ttgtgaagta ccaggactat tccctgggtg ttgtgtttcc ccaatcgtct
    20761 gatcgagagt cgttttggaa ttgaccgttg gcgcttctgt cacaggggcc tgttcaacag
    20821 tggcttcacc agctgggacc ccggcttctg ctggttggac ttctgtcact tcagaagcga
    20881 cttgggcaat ggcttccatc gtaggttgta tagccgtcgt ttcttctgca tgtgcttgag
    20941 cagttcccac caagaaacag aattgagaaa aagccaccaa tgcgagtgct ttcaaccaat
    21001 tcattttcgt ttttgcatac acaagaattc ctccttttcc tgagaatttt atataataaa
    21061 acaaaacgcc gttaccaaaa gtgataacga cgtgaactgt ctcttctatt tttatctggc
    21121 gctcttatct gaacacattt catcaatgat tttaccctcc cactataatt acagaacaaa
    21181 aaaagaacct gcttcgtgga aatcaactgt ccatttccca attggaatac cagctttttt
    21241 ggcaacttca ccatcaccaa atctcatgcc ataccaatta ctaccttcat ccttaatttc
    21301 tttccaacca tatgacatag cttcatctaa tgaatcaaaa atcatgacac tattgccaat
    21361 tgttacagga tctggcttaa gatcttctgg aagagaaata tcaatcatac cataatgatc
    21421 cgattcctca gtattattgt cattactagc tactggtttg gttgttctac tggcttattt
    21481 tgatacaaca agtactctta ttcttctttt acttctccgt tttcaatttc ccattcaaac
    21541 cactccgcaa agtcttgctt aaaaccatct actcgatacc tattttgtaa ataggcatct
    21601 tctgacgtcg taggatctaa ataggtaggt ttattctctg gacgagcata gacacctacc
    21661 catgtttcgt aatctccttc aaaataacta tctaccaaat agcctttttt tctaagaatc
    21721 tcccgaactt gatttttaat tattgatact tgttcaaaac catcactcat tctatcacct
    21781 caaataactc tagattctca taaatattcc cgacaatttc aatcctatca atgatctcta
    21841 acaaatcgct acttatgctt ccccattcgt ataagaattt cccttccgca aaataaattt
    21901 tccataaact tcttcatgat cgtcccaacc aatatcactc tcgaaaaatt ccacgttgtt
    21961 cttatctttt agctcagtaa atgccataag ttcaacatgt tttccaacct cgaaacaatc
    22021 acaccaccca tcaaccgtta cacgtgtgcc ttcaatacct aagaaacttt gtcctcgtgt
    22081 attaaacact aaaactttcc gcattttttg ctcattaatt aatcacgcgc gaaatctagg
    22141 aatcacaact tattcgcttc ttctttataa
//
LOCUS       DBBGRF010000049        22022 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000049 DBBGRF010000000
VERSION     DBBGRF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.049"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(61..1371)
                     /locus_tag="ACIZD4_002141"
     CDS             complement(61..1371)
                     /locus_tag="ACIZD4_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HGC5991046.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1383..2801)
                     /locus_tag="ACIZD4_002142"
     CDS             complement(1383..2801)
                     /locus_tag="ACIZD4_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5991047.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3041..4609)
                     /locus_tag="ACIZD4_002143"
     CDS             complement(3041..4609)
                     /locus_tag="ACIZD4_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HGC5991048.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4613..4894)
                     /locus_tag="ACIZD4_002144"
     CDS             complement(4613..4894)
                     /locus_tag="ACIZD4_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HGC5991049.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4891..5814)
                     /locus_tag="ACIZD4_002145"
     CDS             complement(4891..5814)
                     /locus_tag="ACIZD4_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HGC5991050.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5811..6689)
                     /locus_tag="ACIZD4_002146"
     CDS             complement(5811..6689)
                     /locus_tag="ACIZD4_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HGC5991051.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6676..8013)
                     /locus_tag="ACIZD4_002147"
     CDS             complement(6676..8013)
                     /locus_tag="ACIZD4_002147"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HGC5991052.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8016..9119)
                     /locus_tag="ACIZD4_002148"
     CDS             complement(8016..9119)
                     /locus_tag="ACIZD4_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGC5991053.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9193..10701)
                     /locus_tag="ACIZD4_002149"
     CDS             complement(9193..10701)
                     /locus_tag="ACIZD4_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC5991054.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10667..11359)
                     /locus_tag="ACIZD4_002150"
     CDS             complement(10667..11359)
                     /locus_tag="ACIZD4_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGC5991055.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11381..12355)
                     /locus_tag="ACIZD4_002151"
     CDS             complement(11381..12355)
                     /locus_tag="ACIZD4_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5991056.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12655..13527
                     /locus_tag="ACIZD4_002152"
     CDS             12655..13527
                     /locus_tag="ACIZD4_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5991057.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14109..16307)
                     /locus_tag="ACIZD4_002153"
     CDS             complement(14109..16307)
                     /locus_tag="ACIZD4_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991058.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16539..17531
                     /locus_tag="ACIZD4_002154"
     CDS             16539..17531
                     /locus_tag="ACIZD4_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5991059.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17591..19012
                     /locus_tag="ACIZD4_002155"
     CDS             17591..19012
                     /locus_tag="ACIZD4_002155"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HGC5991060.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMLPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19005..20504
                     /locus_tag="ACIZD4_002156"
     CDS             19005..20504
                     /locus_tag="ACIZD4_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HGC5991061.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20543..21937
                     /gene="uxaC"
                     /locus_tag="ACIZD4_002157"
     CDS             20543..21937
                     /gene="uxaC"
                     /locus_tag="ACIZD4_002157"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HGC5991062.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6667 a         4493 c         3822 g         7040 t
ORIGIN      
        1 atcattaaaa aaaataaagg tcaagctaaa atattattta agcttgacct tattataatt
       61 tcaacgattg tcaaaagtat tgtttgcagc tgtgttgcca gtttctatag ataaatcaca
      121 gcttttgaaa cataagtttt gtactgcttc gattcgcccg aattcttttg cagttatttg
      181 gcaatgagaa aagcagacat cttctatagg cttttcagga aatgctacta aatcaaaagc
      241 tcgggaagga agtgagtaac ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc
      301 tttgactttc gtcatttgct ttgattcagg tatttcttca gccactgctt gccaactttc
      361 tggcatttga gcaaggtcat tgctattttt tctattgtat tcattatgcc agtccattat
      421 ccaagaaaaa ggaaattgta catcaatcat attcagattt tctaccctga tattttcgat
      481 cactccccct ctttcttttg aagatttcat tcgaatacca cagtctgact gaaaaaaatt
      541 gatatcgtga atatatacgt cactaactcc agcactaact tcgctaccaa tagttacacc
      601 gtatcctgaa cggattttac atctagcaac ctcgattctt gatgattttc gattgactct
      661 tgcaccattg ccatctctgc cagacttaat agcaatacaa tcatcaccac aggccaaatc
      721 acattcatag acacgcacat ttgttgaaga atcaatatca atcccatctg tacttggtcc
      781 atcattgttg cggatgatta ctttttctac taatacatcg ttagaataag tgatttgcaa
      841 gttccaaaaa cctgatttct gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata
      901 cagtaaacaa gcgcgtggac gtttaatagc ataatccgca atccaacgaa gtcccttttg
      961 atcgtattca gctcttgtcc cgcttttttg atcttttccc caatacagct cccaccaatg
     1021 gtctccttga ccgtcgatta ttccttttcc ttctataaga atatctttcg ccgagagaac
     1081 attcaaaatc gctgctggcc atttcatttc tacgccggct actcgtgtat cgatttctgg
     1141 aaatgcttcg atatctgttc tccccttgag gactgcacct tcttcaaaga taagatgact
     1201 cttatctttt aaaaaaaggg ctccgactaa ataaatgcct tttggaataa atacaggtaa
     1261 gtgttctttc gcaccttgat cgattgcttt ttgcagtatt attgtatcat cttgttgagt
     1321 gtcgtttgtt ttaaagttca aagcattgat aatccctttt tttgtccgca atacgtttct
     1381 ccctatcttt cattgatttt tttcaattct tcaccaataa atacagtttt tgaacgattc
     1441 agtgggtaac ctactagcaa aatgattgcg gatacaaata agcagaatgc tggtaacaag
     1501 tttgccatcg tataaatcct ttcttgtact aaaactgatt ggatggctcc acctgttgta
     1561 gacgattggt aaccaatgag tgccagcata aatccgccta ccgctcctgc acatgcttgt
     1621 cctacttttc tcgcaaaaga atttactcca tatactgttc catcttctct taagcctgtc
     1681 ttatattgat gataatcaat cacgtcagta atgaatgccc agaccatcaa attgaataaa
     1741 ccagatccta aagtagcgat aaataaaaga atcagatata cccatgcatt tgttatatga
     1801 aggaaataca tcagcaagta catacatgaa gaagcaagta acgcaaatac gcttgcttcc
     1861 tttttaccaa ataattttgt cagctttgta gcaaatggtg ctaaaactac tactgttccg
     1921 taagtaaata aaagagcaac agacattgct tgtttattat ggaagtaatc attgaataaa
     1981 taagtcatat tcgtcccagc taaaatctga ttgatcacaa tgaaaatgtc aacaatgact
     2041 aaaataatca gtgctcgatt agctaacaaa ccttttacca actgagaagc agatactttt
     2101 tcgtttttga caactcttac tctttcagta gtcaatttac aagttaacat atatgcgaca
     2161 aatgctattg cagcacatcc gattgaaatc caaaagaaat gattccctga aacgacttgt
     2221 tgtccactct tgttatgggt atacattaaa atcggaatga agaatcctgt agttgatccg
     2281 ccaatcgcag aaccaatgct tcggaacgtg gacaacgagg tgcggtcatt aggatttgag
     2341 ctaattgctg ctgccattgc tccatacggg atattgattg ttgagagaaa aatcccataa
     2401 acaatgtatg aaacaaaaat ataagcaatc ttcaccgtca ttggaagatg ttggacgaat
     2461 ggcaaaaaca aaatgacagt cactaagcaa aatggatact tcatttttct gatccaagga
     2521 ataaatcggc cagtttctgt taactctgag acatcacata atcttccaac catcacatca
     2581 gcaaacgcat ccaaaattct cgaaatcaag aataacgtac ctacgattgc ccctgaaacg
     2641 ccaagaacat tcgtataata aatcatcaag aaactattga ctaaacctaa aataaaacag
     2701 ttacctagat caccgaacat gtagcctatc ttatcggaaa tcccaaattc ctttttttct
     2761 ttttttactg tatttgctgt aacagcattt tgtgaaagca tttgaattcc tcctacctct
     2821 tctagtaaac gttttcaaaa ttataactct ttttttcttg tttttatatt cacaatgttg
     2881 gctttttatt gcattatctt gacagataaa aaacaaaaaa taatctaaaa acattgatgc
     2941 ataagattga taactttttt tacataacaa tatatacaaa caaaaaaatt cactaactag
     3001 tgaaaataag ttagtgaacc tcatttatta aagaattaaa ttacagatga tcttttccat
     3061 catacttgaa aaactcaaaa tcagcataac ttcctctttt tttatttaga tcatgcactg
     3121 ctatcccgat aaaatttcca gtaaaccctc ctgagagtat acacatgttt ttttgcggac
     3181 ctactttctt ccattcttca gttgatacgt ctttcaaatg aaactgtgct gtctctttct
     3241 ttacagtgac tttcaaaaaa gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt
     3301 gtgctactcc gttttctgat tctatcatac gtaggcattt tcccttgtcc tcattccaag
     3361 taacataaca ataaatataa ttggattcat ttaagtacag taccagtcca gccatctgat
     3421 taaaattatt aggcatgtat tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc
     3481 gaatagctaa caaatgatgt tcgaaggtag attgaagaga ttcaccggaa atcagacgta
     3541 aaaaacctgg tctacatttt gtatcacacc aatcagcatt tggcaaaatg cgtctggcat
     3601 tccagttctt ctttagctct ccttcaaatg tatccataaa ctgatgatct ttttcttgtt
     3661 gtacctcttc atttgtctca atcattattt cttccatcgg agttgtctgg ctatctttaa
     3721 gtcttaacca atcgtcggac gtccaataca cttcttgaat agcggtttct cttcccaaaa
     3781 tagccgcacc gtttaatggt ctggtacaaa gatatgtcat gtaccatctt cctgacgggg
     3841 tttgtactaa gctcccatgt cctgtacatt gcaatgtaga agcaggtttg tcactagctg
     3901 tcagcatagg aaaaccagga tcaagctcgt aaggaccagt aatattcttt gctcggcaaa
     3961 ctgtaactga atgtcctctt cctgtaccgc cttctgccgt catcaaataa taatacccgt
     4021 tacgaaaata caaatgtggt gcctccgttt tcgctaattc tgtacctgca aatattttat
     4081 agatgggacc atcaagcttc ttcttctctg catcatattc ttgtaatacg ataccgctgg
     4141 atttattcgg tgtgtccaga cgataatccc atagttcatt gacaagccat ttttttcccg
     4201 tttcaagatc atggaacaaa gaaggatcaa agccgttact atttaaataa attggttcgg
     4261 accaaggacc tgtgatctca gatgcagtga tcaaataatt gtggacatct ttaaacggac
     4321 ggcctgcact tttgacatct gtgtaaacaa gataaaacaa tccatcagca taactgatct
     4381 gtggcgccca tatacttcca tttgtaggat ttccttgcaa agatacttga gtggtcaaaa
     4441 tatccgttgt atgtgaccag ttgactaaat ttttcgactc atatactcgg attcctggaa
     4501 gccattcaaa agaggagaca ataatgtaat accgctcttt cactcttaat atattaggat
     4561 ctggattgaa tcctcttaaa ataggatttt tcactttgat agtctgcatg attcaggctc
     4621 cttttctcat tcttactcga tataaactga atgccccagc tgctaaaaaa gcaagtgaaa
     4681 taaacaacac aacggcaaac agaccagtca tgtcctgtaa taatccaaat gtattttcta
     4741 aagacaaagt tgaatgatct acagcaagcg actgataact ttttttaaac tctgacgcag
     4801 acatattact taaagtaact gctaacccgc caaagaaaat caaagataga ctgccaccga
     4861 ccattcctag caatagttcc cattttcttt tcatttctga accccctgct tttctaaatg
     4921 tatccattca ggtcttttga tcgatgtttc ataattgtta ttacgttcag agaatttgac
     4981 agtctgttca tttttcttgt catcccaatt atcccaacca gttgggtgaa catgcccacc
     5041 tatcttacac gcttcaaata agacatttgc atacggacgc cacggtcttc ctaaatagac
     5101 gtttctagta tcaggttctg cagtcaaggt acagctttca aaacgatacc ctgttttttg
     5161 atttttcggc gtagatgctg ctgtgatgta tccaggattt ttactggcta agctatggat
     5221 atgacactga tgaaaaacgg catctgcccc accaaatatg aaatccaccg ttccttcaat
     5281 ccagcaatat tcataggtct gacgacaata ctcaggattg gcagaagccg gtgtacaaaa
     5341 aggagtacca tctttttgca aatcaggcaa cggacccgtg cataaggtat cctgataacc
     5401 agatagtcga cagtttttta aagatacgcg atctcctgaa ttgaataaag caacagcctg
     5461 tcctaccttt tctcctggac ctgctgtatt ttcgatgtga agattttcta atacgacatt
     5521 cgatccttct aagaaaaaag tagcacttcg gaaagtccct aactggctac cgtcaagata
     5581 ctcctgtttt gcaaaacgat taccggagat aactactgtt cctgctccca caagtttaaa
     5641 attggataat ctgctttcta tatattcatc atatcttcct tcttttacta tcaagacctt
     5701 tggatggcta tccggcaggc ctgccaaata atcgattcct tcttggatag tttcaaaatc
     5761 cgtcggggta tctatagcat tctttccaat tatcagtttg tctttcatcc tcataaatgc
     5821 tcccttatga attgtttcca aatatttctc atttcttgtg tttccatatg accgcctgtt
     5881 aaagaaaaag aagaaaagtt ttctggacta cccattgatt gatacttttt gtccagccct
     5941 tttctcagct tcagtacgcc ttcgtccaag cacatcgtat cgttttttcc aactaagcta
     6001 agacgagggc gcggagcgat tttttcttgg attgctaacg ttgtataagc tgtcaataga
     6061 tttggcacat agtaataaaa cccatgatga tctaggcggc gatgtagcaa aagtgtttcg
     6121 atgtccacct gtgccgctag atcaatacaa actttgacac gagaatccaa tgctgtcacc
     6181 caccagctta ataagcctcc catagaaaga ccaatcgttg cgagccgttg agtatctgtg
     6241 tcttcccttg tctccaaata atcgatcaag ctgatcacat cataaatacg cattccccat
     6301 aacgtttttc ctgttaataa aaattgtttg aacaactcgc tttcagaaat acctccgcgt
     6361 tcttcaaatc cccaagcatc aatcgaccaa acagcatatc ccattcctgt cagtacttct
     6421 gcaaaagatg gagaagctaa gtaaggagca ccatggatca attcactttt cccgactgaa
     6481 aaatctccgc cgtgagaatg caggtaaagg accgtcggaa acggtccttc tttttctgga
     6541 taagcataga gggctggtac tgtttccaat tcatttaagt acaattgata gtattcaagc
     6601 ataaaaccgt tttgtttttc tcggtataat cgttttccac taggggtatg tctgctagat
     6661 ggagcaccta aaaaatcatt caactgcata agcaaagttt ttacgaacaa ccagttcatc
     6721 catattttct gattgatttg attggaattt ctcaatactg atttctttag tattttctaa
     6781 tagaaatgct ggtccctcgt gattttcaat cgacatctgg ttaaaggaaa ccttacccgc
     6841 aaagccaata taaaatcctt gtctgctcat ttcctctatt cctgtcatca tagcaggaac
     6901 accgggaact gcatcttggg ccatcgagac atcgatattg tcaaatgtga tttcttgtat
     6961 gaattgttcc gctaatccat aaataaaacc tgcagaagca tggacattcc ttgccgtgat
     7021 attcgaaaaa tggatccttc tgaatgctga tgtccgttca tctatcggat aagccttttt
     7081 ttcccataca tacggttctt tccctcgcgg accacagaaa taataaagat tcagtataaa
     7141 tggacacatc acattatcca tgactatatt ggatactcga atatcttcaa cgatcccgcc
     7201 tcgacctcgt ctagatttca atcgtattcc tcgatcagtt tcttggaaga tacaatttga
     7261 aatggtaata ttacgaatac taccactcat ttcacttcct aatacgacac cgccatgtcc
     7321 atggaccatc gtgcaatttg tgatcgtgat attttcgcaa gcgatccttt cgtacgtatc
     7381 ttcagtccct gccttgattg caatacagtc atctcccacg tcaatatggc aattactaat
     7441 acgcacattt ttgcatgatt ctggatcaat tccgtctgta tttggtgaat ccgctgggtt
     7501 caagatcgtc aagttatcaa acgttgcatt actgcaaaga atcgggttga tcgtccaact
     7561 tggtgactgg atcaatttaa tatctttcac agtaattcga tgacagttat ggaaactcat
     7621 caatttagga cgaggataag cgagattatc tggttcattt ctaaaagtat gccaccattt
     7681 ttttccattt ccatctaatg taccgaaacc agtgacagag atgttctcta cattttgagc
     7741 atagatacag gaagcataaa cttttcgatg gactccttcc caacgtgaat gaacaacagg
     7801 ataatctttt ggatcgtcag agaatttcag aaccgctcct gcgcttaaat gaagttcgac
     7861 attgcttttt aaaaataaag ctcctgttag aaattcacct gctggaacaa ctacggtccc
     7921 gcctccgtca cttgctgcag catcaatggc ttgttgtatt gcttcagtat tcaattcatc
     7981 aattgatgcg ccaaatgtca aaatatcata catatttata atgcctccac ttcaatcaat
     8041 gcttgcaaga atgcaccaac gcctttttga tcattacaaa taattggttc actgatgtag
     8101 taagcatatg aaccatctcg ctgatctgct ccgcctaacc ctgctacttg acagttttta
     8161 ttcaagttca gccagccttc ttttgtttcc agaacaaatt catcaagtaa tccttgatgt
     8221 gatttcttca cttgtggaag ccattcttct ttgttcagca gtcccaaacg tattccttta
     8281 gccattgcgt aaacaaacat actactgccg gaagcttcca gataatttcc tttccgtttt
     8341 gtttctgttg ttacttgata ccatgtcccg ctgttttctt cttgatatgg aagtaatgca
     8401 gccagtgtct tttctagaat ttctttcagc aaagaacaat ctgtttcttc atgaagtaat
     8461 tcataggtat ctgctgcagc catcaaatac cagccaatcg atcggctcca aaaatgatgg
     8521 gatagacctg tttttggatc agcccatggt tggaccttct tttcatccca tgcatgaatc
     8581 agcaaatttg tttttggatc gaatagatgt ttataactga tttcaaactg tctcaaaaca
     8641 tcttggtaat ctttttcttc actaaaattc tggataaatt cagcataaaa aggagaaccc
     8701 atatataagc catccaacca aatttgataa ggataaattt ctttatgcca aaaagctcct
     8761 tcggatgtgc gtggatggtt tgccaactgc tgggaaagga gttctgctgc ttttttatat
     8821 ttttcttcgc ctgtttcttt gtacaataaa aagaaaagct ttcctgtatt tacatggtcg
     8881 atattgtatt cttcaacgct gtagccacgg atcgttccat cttcttgcac gaaatagtcg
     8941 atattgtctt ttatgaaatc aaaataaatt ttttcttggg ttcgttccca aagtaattgg
     9001 aaccctttaa gtacgacgcc atagtcataa gaccattttc ctttatacca cttttcttca
     9061 tataagcgag gtgttctttc catgatactt tttgctaatt tctttgacca gttttccatt
     9121 atttgctctc ctttaaaaat taaaatagga tttgggacaa ataccaagaa gtatttgtcc
     9181 caatcgtcta tattactgtg ccgctgcttt gtatgcttcc tcgtactctt gtgtgattcg
     9241 atcgcctcct tgtgctttcc agtcttctac agcttttttg aatccatctt cgtcaagctg
     9301 tcccatgatg tattgcaccg tagcatcaat gacgattttt tcaatttctg atcctacttc
     9361 attgttcgtc ggtgaatcca atggcacaga aggatccatt acagcaaatt cttcattttc
     9421 tttgatcaat tgattagaga attctttttc agggtctgta tctttgaaag agaacgtcac
     9481 ttcactagga cgagagcttg ataacggttg cacctcttgt tgccaaagat ccatatcgat
     9541 aaattcgata gaaccatcat cattcaattc ataatgcgtt ccttcgatac cgccagtcat
     9601 caatttatac acatcttctt ctaaaagatc atcaacaaat tgaagtaatt tcttcaattg
     9661 tgcttcgtct tttacttgag atttgggaaa tgctagcaag ccgccaatac catttccttc
     9721 tgaccaaaca tgataaccgc cgccttcacc atctgagatc ttgtttacag gcactaattc
     9781 catatcatct tgaatacctt gacccatcgt cttcagattc ttgatatcca ccattccagt
     9841 gtagattcca gttcttcctt gtgcaaattg ttcttgctga tcagtctttt gggtaactgc
     9901 aaagtcttgt gccaaatagc cattctcaaa tagatctctt gaaaaattca aagctttcat
     9961 atactcttct gtatcaaatt ctggagtgaa tttgccatta tcgtctacag cccagccatt
    10021 tggtgctcca aaataagaag tgaaaagttt aaagctggta taacgaatat cactaggcgc
    10081 acgatcgcca aaaccaactg tgtcgtccac accatttcca tcaggatcgt tttctgtaaa
    10141 ttgtttagct acttcataaa gctcatccat ggtagttgga acatctagtc ctagattatc
    10201 caaccagtct tttcgaatga ctaagccagc acgagcgtag tctttttgta tcggtacgcc
    10261 gtacaaggca ccgtcgatac tcgcagcttc gattctatct tcagaaattt gacttaaatt
    10321 tttatagtct tttaaatatt ctgatacatc ccagaatacg cctgatttta acgcattgcg
    10381 gacagaagag tttttcaaca tcgcaatttg aagtgtaacg atatctccta gttcatcaga
    10441 agccaatgca gttgttaatc tttcttcttt tgaagcatca ggaatccagt tgaatgtcag
    10501 ttccgtatcg gttttttctt cgatcaagtt cacaatcgtg tctgtaggcg gtgaagcatg
    10561 atgcaaaata tttaaccaag tgattttagc ttttccatct tctgtctctg aagaactgtt
    10621 acttgaactg ctgccgcatg cggcaagtgc tagaattcct gcaaaactaa gacctaattt
    10681 tacgagcgtt gcttttttca taaattttct ccttcactgt tttaataata tttttgtttt
    10741 cttctgtttt ttctgtatat gagttcttcc attccaaatg gcaaaatata gaatttgctg
    10801 tccacgtgac tgcggaaaag aagagactgc caccgataaa ggttaaaaca cctggcattg
    10861 tttggatgat catcagataa atccctacca tacttaatat caacactaat gagtaatgaa
    10921 gatgtgagaa tccgaataaa aatgccattt tcattttgaa aaaatatcct ttccaatcat
    10981 aatgagccat gattgggaaa atatagagtg ctgagagcac atatatgaac gcagcaatat
    11041 acaaagcgat cctaagatac caattgtgta tgaaagaaag atccacaagt aaaacaatcc
    11101 cgatggcgcc atatatccag ctcatcagca aggtttcacg atagttttct ttaaaatatg
    11161 tgaagtacgt tttcgtcaaa ggaaacgttt cttttgagcg cagccatttt ctaatcactg
    11221 caaccatcgc atacgatgca ggaccgaaag taaaaactcc caaacctgcg atgactaaac
    11281 cgccccacag aaaattcaaa taaaccaact gtaaaatacg atttagcctt ccgtttattt
    11341 tatctaatga ctgcagcata tctttccctc tctttctatc ttagtaaacg ccgtcttctc
    11401 ctagcttttt ggcaatctta ttagctaaaa ttaccataaa caatcctacg acccctttaa
    11461 acaatcccat tgctgtactg aaacttaact gtccattctt caatccagct gtataaatat
    11521 aggtgtcgaa aatttctgca acgcttcgat tcaatgaatt caataacaag tacatatgct
    11581 cgaaccctaa gtctaatgtc tgaccgattt ttagaatcag caaggtaatg attactggac
    11641 gaattgccgg caatgtaaca tgccatgttt tgcgtaagcg tcctgctcca tccatttctg
    11701 cagcttcata caactgtgta tcgactgcag ttatcgctga aaggtagatg atcgtagacc
    11761 agcccaactc tttccagatc acttgtccga tatatactgt gcgtgtccat tcaggggatg
    11821 ttagaaaact gattttttca aatcccattg ttgcaaggaa ttcattcaat acccctccgt
    11881 caacattcaa aaatacataa gtaatcgaaa caatgattac ccaagacatg aagtgaggga
    11941 tgtaaatgat cgtttgaatc ccgtttttca atcgtttgtt cgttacttca tttaatagta
    12001 aagacaaaat gattggcatc ggaaaaaaca cgaagatatt taatccgaac aagatcaacg
    12061 tatttcttaa taatgtaaag aatgtcggtt ctgtaaacaa acgaatgaaa tgtttgaaac
    12121 cgacccaagg acttcccatt attcctaaaa atggttgata atcttgaaaa gcaataacga
    12181 gtccccccat aggaagatac ctaaaaatca agaaataaag gactcccggc agaatcatca
    12241 catataaaaa tttattcgtt ttgattcctg caattatttt ttttcgtctt ctgagctttt
    12301 cttctttttt cgatagcgtc agttgaaatg gttcttgttt ctttacactt tccataagcc
    12361 cctccttagt tttgtgaatg tttgctgctt atgacttcat gatagataac tatctgaatt
    12421 acgtatataa tcatttttat cgtaagtaaa aacgcttaca tagcaatgat ttttgtgcta
    12481 tacaaaacga taaagtgtat tttttcacaa ataaactacg catagcaaac cttctatttt
    12541 tttctatctg acacttagca taggaaatga ttatatacgt aatctttcac cgatgataaa
    12601 ttgaacatat agaaacagaa acatttaatt tattttgagg aggagcctat ctatatgaaa
    12661 aagaaagtct ctataggaga aagaagtttt acacttttca acaatacgtt tctaattttg
    12721 ctagctttga tctgtatcgt tcctttttta aatatcatcg ctacatcttt tgcttctaca
    12781 caagaagtcg tcgcgaaaaa gtttatcctt tttcctacta ccttttcttt agacgcgtat
    12841 cgctacattc tttctacgcc gaccattttt agagcacttg ctgtttcgat tggtgttaca
    12901 ggtgtcggaa cgatcgtcag tatgtgtgca acttcactga tggcctacgg tctttccaga
    12961 aagtatttgt ttggtcgagg tttcgtcaac tttcttgttg tattttctat gttgttcagc
    13021 ggggggatga ttccaacgtt cttagttgtt cgttctctag ggctggtcaa ttcttactgg
    13081 gccatgatcc tgcctgtggc tgttaatgca atgaatatga tcattatgag aaactttttc
    13141 caagccttgc cggatagttt ggaagaatca gcaaaaatgg atggttgcac agattttggt
    13201 gtatttttca aaattatgct gccattagct ttaccgtcta ttgctactat ctcgcttttt
    13261 tatgctgtta cttactggaa cacttatatg actgctattt tgtatatcaa cgattcatct
    13321 aaatggccga tacagattct tttacgccaa atcgtcattg tatcaagtgg gatgcaagca
    13381 gaaagtagtg ccgttgatgt gattccacca gcacaaacag ttaaaatggc tgttatcgtt
    13441 attgcaacag tgcctatgct gattgtttat ccttttgttc agaaatattt tgtcaaagga
    13501 gcactcgtag gttctgtcaa agggtgatta tgtactgaac gcaaaatggt agttgtgtca
    13561 gaagtggtca gcttcaagaa ataagaaggc atttacgaaa attgcttctt aaatttttgt
    13621 gaaatttcgg cttatttttc gaagaatcta ctcctggaac accgtgtatc agaggttgtg
    13681 aaagagacgt tcagccttga gcgatgataa aaactctcac aaacattgcg acgagtaacc
    13741 cacaggagca ataagaagcg attttgaaaa atagcttccc atatttcaca aaattatgcc
    13801 ttattgtcga tagcctgtct cttgaacgcc atttattcgt aaaaaagaac tgtgacaaga
    13861 cttttgtcac agttcttttt gcgtgcttag ccttgaaatt taactatcca taaatacaaa
    13921 tactagggtt attctaactt cttttattgc ttgaatcagt ccacaagaaa aacagcctct
    13981 tgattaaacg gcgtttatct tgttgattct gcggcaataa aatcagccag cagcaaaaca
    14041 tgaagtgctg ttttttgctg tcctctttta ttgcttgaat cagatcacaa gaaaaacagc
    14101 ctcttgattc acaaatattt ttttcgatat tctcccggcg taatcgattc cttcttttta
    14161 aagaaacgaa taaaattttg cggatttcga tattgcaatc tttctgcaat ctcttttacg
    14221 gagaggttag tctctttcaa ccattttttt gctacctcta aacgatgatt ttgaacaaaa
    14281 tcaccaaatt tttctcctgt ttccttttta aatacattac ttaaatagtt agggttataa
    14341 tgcaacctat cagcgatcac atctaaagac agatcacgat catattctgt gtagacgata
    14401 tgcataatat tctccgacaa atttttaaat tcatgatcag tgattgcttg agagcattct
    14461 gtgattggca gaactaattg ttctaaaaca agtttttcta gttctttggg atgataattg
    14521 ttcagtgctt ttacataaat ttgtttcatg ttatcaaagt tttttgaatc tactcccaat
    14581 aactgtccta attgaacgag ttcattgatc aagcggaccg aaactacttc ccgactcaaa
    14641 ggatttttat tttgtgcaaa caatgcatca atcaattcat gtactaaatt cttcacttcc
    14701 tgatttccag aacgaatggc ttcaaacaat cgattttgtt cttctatcgg atatctaata
    14761 agtgtttttt catgagcagc aggaacgatt tcctgataaa aaataattga acttggacca
    14821 gtatttacac gataatacag ggcttctttt gcccgatcaa ccgattgctt gctttcattc
    14881 agcgtttcga accggttact gatgcctata ctgatagtta aattcaagta ttcttttaca
    14941 cgtttttgaa tgagtcggca atactccatg acttttttgc ttgcttctgc atcatcttta
    15001 tccattcgat aaatagtggc ttgcatttct tcattcaaaa cgatcggcag cattcgattt
    15061 tcctttggca caatttccgt gatcatgttg ttgatcgcta aaagtagcaa atcacgctcc
    15121 ccaccgtgac tatcttctaa cagatcgatt tgaaccaaag ctgtataata gcagtcattt
    15181 tgagaactat aaccaaattg ctgcaaccgc tgatctagtt ctcgcctttc tactcgattt
    15241 ctaaataaac taagtacaaa tagcgtttcc agctgtggct tttgggtaac taagtgtgca
    15301 cttaacgctt ctttttctcc tatgatccga ctgactgatt gagcgaccaa atctagttct
    15361 ttcccactga atccttttga tttaagattc agacgttcct gtatttgaga aatcggacgg
    15421 gcaaatctgt ccgaaaataa gtaggaaaaa agaccaatga gtcctaccag tgttaaagac
    15481 actgcaacta gcccgattct cagattgcgg atcattgcgc caattgcact agagtcaact
    15541 tctaatctgt aaatccaatt attataatct gatttcagta ctatatacgt tttatctttt
    15601 tctcttatca ctttcagctg attgtaatct agatccacgt ccgttaatac agttggttgc
    15661 tctttatttt ttactgtctg agtagtaaaa aggttgccaa cttcgttttc aatagaaagt
    15721 atgtcttctc cactttcacc aacaacttgt tctattgtat gtttctctat cgtagcaatt
    15781 cccaatgcat atttttcttt ttcaaacatt ggcaaagaaa tcaccatttc gattcctttg
    15841 tttttctttt gccaaaataa attatttttg ttatttatgt acttctgttg atacttttca
    15901 acttcctctt cggtcagttg actcaacgat ccattgatta ctccccattt accagccaaa
    15961 ctgactaaat cataattatt atcatccata acaatcgttt ctataaaatt tagttctttc
    16021 ctgatttcag aataagtgga gtaatctgta tatgtcagcg gatgcttgaa tatgtccgag
    16081 aaatttttgg tcgaaccata cgtagaaaac gaatattcaa tcgttctaat tttccattca
    16141 acgttagttt taacttgcct gagcaaattc tttttgtctg ttaaataact cgattcgatc
    16201 gattcatagg tattctggta aatgaataaa ctaaatccta tgacaagtac ggctcctaat
    16261 aaaaacatcg gtaaaaatat tttataaaat actgtacttt tcttcatttt cttcctctcc
    16321 tccttttaaa ataaaaggct ttcatttttc tgtaaaattg atactcatct aattaaatga
    16381 gcattccccg ctttcaagaa tagcataatt aaaaataaaa atccaagtaa tttttaacgt
    16441 gtgcaatctt ttcatatcaa agatctattg acttatcgta gttatcgtaa tatgatgaat
    16501 gcgttaacaa aaagtgaaaa agtaaggaaa atgatggaat ggtaacgatc aaagatatcg
    16561 ctaaagcagc tggcgtttct catacgacag tttctcgtgc tttgaataac agcagtttaa
    16621 taaaaaatga aacaaaacaa aaaatacgac aactagctaa ggaaatgaat tattcgccaa
    16681 actatagtgc aaaaggttta gtgaatcaaa aaaaatatct aatcggacta tttttctcaa
    16741 gtttgcataa aggaacttca tcaaatttcc tagcagattc cattgcaggc atccattcag
    16801 tattagacac aaattacagt ttatctgttg aaagtatcga tgttgttgat ttaacagaaa
    16861 tcaacctgca acgctacgat ggactgatcg ttatgagtca aagtgatgat gatcagcctt
    16921 tcatcgacta tctcaaagaa aaagaatttc ctttcgttgt tgtcaatcgt cacatcaatg
    16981 atccagcggt tatcaacgtc actgccgatg atgcggccgg tgttatgcag gcagtagatt
    17041 acggtattgg atgcggacat acgaagatcg cttatattgg cggaaagaaa aattttcgtt
    17101 cgacaaaaga acgggaaaaa ggggtattga aaagtctaaa aaaagcgagc atccctgtca
    17161 atctagccta ttttttaaca ggagattaca gcttagaaag cggcctccaa aacatggaat
    17221 acctattatc actttctgac ctgcctactc tggttttttg cggcaacgac gacatagcga
    17281 ttggtgcatt gagagctgta catttagctg gcctccgtgt tccccagaac atttctctga
    17341 tcgggttcga tgattctcca gtcgtctcct atctcaatcc gccgcttacc accgtacgta
    17401 agcctttgaa agaaatgtgt caagaaggaa caaagctttt actagatttg atcgaaggca
    17461 ggacgatcga acaatctaaa attgagctct ccaccttgtt gatccttcgt gagtcgatca
    17521 attacttgta aactacaagt aattttatat aaaaatgtta acgtgtgcat aacacagaaa
    17581 ggaagtttat atgaaaaaac tgacaaaaga attagtgaaa aaaaacgaag cacctgtaaa
    17641 agttcttcag tttggtgaag gcaattttat gcgtggattt attgattggc agattcagca
    17701 gctgaataac caacaattgt ttaaaggtaa tgttgcaatc attcaacctt tagaacaagg
    17761 tcttggaaat atgatgaacc agcaagataa tttatatacg gtcattttac aaggactcag
    17821 caatggcgaa atcgttgata cttccgagat tatcaccgta gtagaacaaa tgatcaatcc
    17881 ttatgatgaa tgggatgctt atctatctct agcagaaaat gacgacttgg cctatatcgt
    17941 ctccaataca acagaggcag gaatccaatt cgtggagact gataatttaa cagatactcc
    18001 cccacagagc ttcccgggca aactgacagc ctttttatac cgacgtttca aattaaacaa
    18061 agctggcttt accatcattc cttgcgaact gattgacaga aacggcgaac gtctaaaaga
    18121 aatcatttta cgctacgcag aaaaatggga tttagaacct gcttttgttg agtggttaga
    18181 aaaagaaaat gttttctgtt gtagtttagt tgatcgcatc gtcccaggtt atcctcgcga
    18241 agatgcaggt gttttcaatc aacggcataa ctatgaagat caattgatgg tcaaagcaga
    18301 accattcatg ctttgggtga tcgaagggcc taaagaattg gagaatcaac taccattcaa
    18361 acaggctggc ttgaatgtca tcatcacaga tgatatgact ccttatcgtg aacgtaaggt
    18421 gcatttgctt aatggaccgc atacagcgat gctccctctt gctttgttgg cggaattgga
    18481 aactgtagaa gaagtaatga aagatccttt attctccgca tatgttgatc agttattcaa
    18541 tctagaattg attcctatgc tttctttacc taaagatgaa ttagccattt atgctgacca
    18601 aatcaaagaa cgtttcttga atccttttgc ccatcacaaa ttagaagcga tttcattaaa
    18661 tagtgtttca aagttcagca cccgtctgct tccagtgttc aagaagtata tcgaagaaca
    18721 aaatcaggta ccaccgttaa tcactgtttc actagctgcg ctacttctta tgtatcgagg
    18781 cgatcaagta aagccacatg atgatgaaaa gacgataagc gaatttactg atgcttggtc
    18841 tgataatgga acagctattc ctcgattatt gcaaaacgct gcgctttggg gagaagattt
    18901 gtctcaaata ccgaatgtga cagatacagt tcaagaaata gctgcaaaga tcgatcaaaa
    18961 aggtgtccgg tcagtattac aagaaatgaa aggaacgatg gtccatgctt gaaaccctgc
    19021 aaccaacaat gaaattaaat cgacgagaca gtgtggtcgt cgcattaacc cctattccaa
    19081 aacaaacaca actgacgatt gatcagcaaa cgatcaccac tcttgaagat atcccgcaag
    19141 gtcataagat tgcattgggt gatttgaaag ctggagacaa cgtgatcaaa tatggctatc
    19201 caatcggtca tgtgacgaca gacgtaactg ccggtcaatg gctgcacact cataatgtaa
    19261 aaaccaatct ttctggtgaa ttggattatc gatatgaaaa agatgtccat ccaagtcatt
    19321 acctttttga gaaccgaaca tttcaaggtt acttgcgaaa aaatggaaaa gtagggattc
    19381 gtaatgattt gtttttagta cctaccgttg ggtgtgtgaa tggcattgct gaactgatcg
    19441 tcaaacagtt caaggaaaaa catccagatc tgggacagtt tgaccatatt acgattttaa
    19501 agcatcctta tggctgttcg cagcttggaa aagatcatca aaatactcga gaaattttag
    19561 cggacgcagt aaatcatccc aatgccggag gagttttagt atttggatta ggttgtgaga
    19621 acaatacagt tcctgaattc aaaaaaattt taggtgaata tgatgaagaa cgagtgaaat
    19681 ttctagtggc tcaagatgtt tacgatgaga tcgaacaagg tgtggctcta ttagaagagc
    19741 ttttaacagc ggcggaaaat gaccagcgca tatcagtccc gctctctaag ttgaatgtcg
    19801 gtttgaaatg cggcggttct gatggtctat cgggaataac tgctaatcct ttacttggtg
    19861 cattttctga ctacttgatt gctcaaggag gcagcacgat cttaacagaa gtgccagaaa
    19921 tgtttggcgc agaacaagta ttgatggcac gagcggaaaa tgaagaagtt tttgactcaa
    19981 tcgttgactt gatcaatgac ttcaaacagt atttcttgtc ttacggggaa ccagtttacg
    20041 aaaacccatc tcctggtaat aaagcaggtg ggatcactac attagaagat aagtctttag
    20101 gctgcacgca aaaatcagga agctctcctg tcgttgatgt gctacaatat ggcgaaaaaa
    20161 tcagaaaacc agggcttagt ttattgcaag ctcccgggaa tgatcttgta gctgcctctg
    20221 ctcttgcttc atccgattgc cagttggtct tgtttaccac aggaagaggg actccgtttg
    20281 gctcatatgt cccaacggtc aaggtatcta cgaatacaac tctttttgaa cgcaaaggtc
    20341 attggatgga ttttaatgca ggcgtcttat tagaacaacc aatggaagta atcttagaat
    20401 cgtttgttca aaaaatcatc gctgtagcta gtggagaaga aacgaaaaat gaacaaaatg
    20461 acgttcgaga aattgccatt tttaaaaacg gagtaacact ttgattttca taaaacagta
    20521 taaaaagaaa gaaggaagat ttatgttttt atctgatgat tttttattaa aagacgattg
    20581 ggcgaaaaag ctttaccatt cctacgcaaa aaacatgccc attattgatt atcactgtca
    20641 cttagatcca aaagaaattt acgaaaacaa caatttcagc aatctgacag aagcttggtt
    20701 aggaggcgat cattacaaat ggcgcttgat gcgagcttgc ggcgtgcctg aagaaaaaat
    20761 cacaggaaat gcttctgatt ttgaaaaatt tttagcttgg tgtcaaaccg taccaaaaat
    20821 tatcggaaat ccgctttaca gttggtcaca tcttgaattg aagcgtttct tcggtattga
    20881 cttgttgata aatgaagaaa atgcagagaa aatttggaca caagcaaatg aaattttggc
    20941 agctcctgat tttcgccgtc gggaaatcgc aaaaaaatcg aatgtagaag tgatttgtac
    21001 aacagatgat cccgcagacg acttgcacta tcatcagttg cttgctcatg aagaaccaga
    21061 tttgaaggtt ctaccttcat tccgtccaga taaagcactc aatattgaaa aagaaggatt
    21121 taatgcatgg gtcacactac tggaagaagc agctgaccaa acgatcacca cctatcaaga
    21181 actgatagaa gtcttagggc agcggataga atacttccat caacatggat gtcgtgtttc
    21241 cgaccacgct ttagacatct tacgctataa agaagcggat gaaacagtat tagaagagat
    21301 ttttcaaaaa gcacgagcta acaaactatt atcttcagat gaaatcgatg cttatcttac
    21361 agaaacactg atacatttga cccacttcta tcattctcat aattggacga tgcagctgca
    21421 catccatgct tatcgtaact gtaatacaca aatgttggaa aaattagggc ccgataccgg
    21481 ctatgatgga atgaatgatc tttctttgac tattcctctg caaaaattat tgaaccgtgc
    21541 agaagaaacg gatcagttgc caaagacgat cctttattca ttgaatccga atgactatcc
    21601 tgcgatttta gctttgatgg gctgtttcca aaaagaacag aatggaaaac tgcagttagg
    21661 ttctggatgg tggtacaacg atactcgagc tggtatgcgc gatcaattga cacaatttgc
    21721 tgatggtagt gctttgggga attttgtcgg catgctgaca gattcaagaa gtttcctgtc
    21781 ctacactaga catgaatatt tccgtcgtgt tctttgtgaa tttttaggcg aaatggtcat
    21841 gcgaggagaa gcacctgaag atgaacaact tttaggaagt ctagttcaag cgattagtta
    21901 tacaaatgct aaaaattact ttggcttttt tgcctaattg attaatagta acagtaacga
    21961 atcaaaaaca ggatagtgaa ataacggaat ccgtttatcc acgttttaga gaagaagacg
    22021 ga
//
LOCUS       DBBGRF010000050        21929 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000050 DBBGRF010000000
VERSION     DBBGRF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.050"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            238..1455
                     /locus_tag="ACIZD4_002158"
     CDS             238..1455
                     /locus_tag="ACIZD4_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGC5991063.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(1681..2565)
                     /locus_tag="ACIZD4_002159"
     CDS             complement(1681..2565)
                     /locus_tag="ACIZD4_002159"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGC5991064.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(2660..3097)
                     /locus_tag="ACIZD4_002160"
     CDS             complement(2660..3097)
                     /locus_tag="ACIZD4_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991065.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(3314..4225)
                     /locus_tag="ACIZD4_002161"
     CDS             complement(3314..4225)
                     /locus_tag="ACIZD4_002161"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC5991066.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(4602..5240)
                     /locus_tag="ACIZD4_002162"
     CDS             complement(4602..5240)
                     /locus_tag="ACIZD4_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5991067.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(5244..7226)
                     /locus_tag="ACIZD4_002163"
                     /pseudo
     CDS             complement(5244..7226)
                     /locus_tag="ACIZD4_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
     gene            7406..8071
                     /locus_tag="ACIZD4_002164"
     CDS             7406..8071
                     /locus_tag="ACIZD4_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991068.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(8468..10501)
                     /gene="brxL"
                     /locus_tag="ACIZD4_002165"
     CDS             complement(8468..10501)
                     /gene="brxL"
                     /locus_tag="ACIZD4_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HGC5991069.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(10619..13141)
                     /gene="pglZ"
                     /locus_tag="ACIZD4_002166"
     CDS             complement(10619..13141)
                     /gene="pglZ"
                     /locus_tag="ACIZD4_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HGC5991070.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(13257..16889)
                     /gene="pglX"
                     /locus_tag="ACIZD4_002167"
     CDS             complement(13257..16889)
                     /gene="pglX"
                     /locus_tag="ACIZD4_002167"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HGC5991071.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(16953..20624)
                     /gene="brxC"
                     /locus_tag="ACIZD4_002168"
     CDS             complement(16953..20624)
                     /gene="brxC"
                     /locus_tag="ACIZD4_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HGC5991072.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(20649..21224)
                     /locus_tag="ACIZD4_002169"
     CDS             complement(20649..21224)
                     /locus_tag="ACIZD4_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HGC5991073.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(21224..21823)
                     /locus_tag="ACIZD4_002170"
     CDS             complement(21224..21823)
                     /locus_tag="ACIZD4_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HGC5991074.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         6807 a         4244 c         3163 g         7715 t
ORIGIN      
        1 gggaacatca ttgacgaatg atgttctcct ctattttcta tttttagatt atagtgaaga
       61 gtgaaagaaa gttcgaacaa agccttgagg actacgagtc cctatcaaaa accgaacttc
      121 tttactgtca ttttagaatc aggtttacgt atgttggggc catgagcccg tgtataggaa
      181 attggaatcg aaatgaagca gtaaagttct ttcaaaactt aaaaaggagg aaaacaaatg
      241 ccttacattc ttgcattaga tgtttcaatg ggacacagct acagtgtcct atacaaagac
      301 gacacctgct tatttgaaga cgagattgaa cacactcaaa gaggatttca tgcattactc
      361 gaagagatcc agcacttgcc tgagcgtcca ttgattgttt ttgaagcaac ggggatttat
      421 tccagaccag tcgaaaagtt ctttcaagat catcactttt cttactgttt gttaaacccg
      481 ttagaggcga aaaaacagat ggaagaaagc accttacgca gttggaaaac agataaatcg
      541 gatgcccacc ggctcgcaca gactcatctt aaaaatcaac gtcagccaaa agaagtacaa
      601 agcaattttt acttagagat gcgcgattta gcccgttttt atcaagaaat tgagaagaaa
      661 atcactcgtc tgcgcatgga tttacacaac tgccttcaat tgacttttcc agagcttgaa
      721 cagttctttt caaacaggct gaccccttac gcattgacat tgatccgtct ttttccccat
      781 ccagattttg tattggcatc tactcggaca aaaataaaaa ataaactgat caacgaaaca
      841 cggaaaaaaa tctccgcgaa tcgtgccgag caaaaggcag atcaaatcat ccactatgca
      901 cagtgtgcct atccagctgt tgaaaaagac agtatccact gtcaaaaaac gatctattac
      961 gccgaacttc tccaagattt actcgaacaa aaaaaagcac tggcgacaca aatgatcaaa
     1021 aaagccgaag gctctccttg ctttttgttg taccaaacgt tccctgggat tggcgcactc
     1081 acagccgctt tattgctcgg tgaattagga gatatcacac gatttaaaac ccataaacaa
     1141 ttgaatgcct ttgtcggaat cgacatccga cggtatcatt caggtaagta tactggccaa
     1201 gaccgcatca ataagcgtgg taatcccaaa gcacggaaaa ttattttctt caccattcga
     1261 aatatgattc gccagcaacg cgcagctcct aatcatattg tcgattatta ctacaaatta
     1321 aaaaagcaac ctatccctaa gaaagataag gttgccacag ttgcttgtat gaacaagctt
     1381 ctgaaatgta tgcacgctat ggttagggca catacagagt acgactatgc gtacgcggtc
     1441 tcagtggacc attaactaaa ccacttacag tataccactt ctttgcccag atcgaaaatt
     1501 ttttacgaac ggggctttat ttggtgtgct ttgattttgt cgctttcgtt tacgagctat
     1561 ttttcttgca ccttttactt gactaatcgt aggaaaaagg ctgtgacaaa agtcttgtca
     1621 cagtccctta ttccgaacaa ccgatgtcct cctgacaact cttcggtcac aacctccatt
     1681 ttaacaataa acctgtaaat gtgagggtaa cactttgatt gtcacaggta atttatcccc
     1741 ttcatctcca tcaacattcg tcgtcaattc ttcctcatca gctaatgaca caactaattg
     1801 ctcacaagta agataggcta gatttttcgt agattcatct actcctttta ataggtctgg
     1861 caatgtttta agcgtatcga tcaaagaaga atcttttaaa taaaccaaat ggagcttacc
     1921 atcatccact tttgcatttg gaagtaatgt ttcaaaaccg cctactgagt tagttagtcc
     1981 tatcagcaag atactgctct caatttcttc cttctttcca tcaacttcta cgtgaaacga
     2041 gtaggattgt gtggaagcta actgtttgat tcctgacatg aaataagcta gttttccaaa
     2101 tttcgtcttc ttctccgcat ctacatcatt gattgcttca gggatagagc caattgcgac
     2161 gacattcata aaatagtcgt catttatttt tccaatatcc aatggcttga ctgattcaat
     2221 cgaaaaatga ttgatcgctt cctcaggttc tagcggtatc cctaatgctc gagccaagtc
     2281 attcaccgta cccaatggga aaaatccgaa atttggccga tgttcttgtt cagcgattcc
     2341 actgattcct tcgttgactg ttccatctcc gcccatgaca aacacactat gatacccttc
     2401 cgtagccgct tcgcgagtaa agttttttgc atcccctgct ttttttgtat gcaagacgac
     2461 cacttcatca aacaccgatt ccaattttgc tatcgctaat tgctcaaatt cctttgcttg
     2521 ttcaccgcct gaactggggt ttaccactaa taaaactttt ttcatcactt tctttccctt
     2581 ctgattgatt tctttaatat aacgatagca taaagaaaaa aattaggctg tgatgaagta
     2641 ctgttcatga aacattcatt tattttttga caagataaaa tacccatact atgaaactga
     2701 ggaaaattaa aacaatgata taggaaataa aagaaaatga taggcattgt atacctaata
     2761 aagtaaaaat cttaggtggc agataaaaac acaaaaatag caagagaatg taatagcgtt
     2821 tcttccactt tttgttatca gaccttatag cgatcagagg aataccaaat gcataactga
     2881 aaaactcttg atgtactgtt aatatgtcac gaccttgaat aataaatgca acaatccccg
     2941 ctataattag tgtgcctaat accaaaacgg aaaattgatg aatatatttt atatacaaat
     3001 gatccattgt acttcctgcc tttttatttg tgagaaaaac aaatccgtat acgtgaataa
     3061 cttctagaaa taaaagaaat ttgcaaaacc actccattta tctacttcta cgtgcatttt
     3121 ttaatatcgt tttctttatt taagattata cagaaaaata tctagggtgg ctggattcta
     3181 agtaaaaaaa atttttaaaa taaaaagaac taaatcaagt aataattaaa ctactgttga
     3241 tttagttcta ataaaaagat ttagatgaac agttttattg atttaaatag ttcatatttt
     3301 ttatttatac cgcttattta ctacttgctg tactagaatc tgaagtgaat gtactcaaaa
     3361 cattttcaaa gtctttgtct ttgattttta cattagcgtc tttcaatact tcgccaatta
     3421 ctttattctg gaaggtactg tcacttaatt ttgtgtctgt tgcaatttct ttcaattctt
     3481 ttttgtattt atccatgtcg ttgcctttgt tttggttttt caccatttta accacataat
     3541 attccgtagt ataagttgaa gcattggtag aagtgatcac atcagaaact tgaccatctt
     3601 tcaacttaaa ggctgcttct ttgacttctg ccggaaccgt tgtagtagtg gaatcaaatt
     3661 tcacttttcc gccatcttct tttgtcgtag tatcagttga cttgtctttg gctaatttag
     3721 agaaatcgtc tcccttatca gcagctttct tcacatcttt tgcatcatct tcacttgcta
     3781 cttggataat ttgagcttcc acttctggat ggaaagattc ccaagccgtt tttaaatctt
     3841 catcggtcaa tttgatatgt ttctttagac cttcttgaaa ggctagactt tgtttgatac
     3901 tgtctttgaa tgtttgttct gtgtaacctg cagatttcaa ttgtgaatca aatgaatcac
     3961 ccaattgttt ctttgtttga tcatattggg aatcgatttc tttggttgat acgtcatctc
     4021 catatttatc ttcaaatact tgataaacga tcaactgttg cacagcggaa tctgctcctt
     4081 gcattttttt caagctatcc attacttctt gttcgctgat tgtaccgcct ttataactaa
     4141 cggctgtttt ttcaccggca ttcgtacagc ctgacaataa gccagtgcct agtacgatgg
     4201 caagtgctaa aaatcttttt ttcatttatc aattctccta cttttcgttt tttgcgaatt
     4261 gctaaaaaca aaggtgttca agatgaaaat catcaagaac acctttacta atctgctcga
     4321 tacgtcctga atagatataa ggctacacaa tccagaaagt tcgctcagca gaataaatgt
     4381 caagtagcac atcacacctt aatatactac ttcttttgtt accgtttttc aagtctatct
     4441 tgcgttccgt atttaacgta actaattctt agaacaaatg ttatcgattt tgtttttctt
     4501 cttccgctgt tgggatattc aaatcagaca cttttatgtt cgattttcca gacatttttt
     4561 tgttgttttt attagaaaaa gtttgttttt tcatttgttt tctaaagcat gatcttcttg
     4621 tttcctattt tggtcagata tggatcatgc gtgaccacga taactaacgt accttgggaa
     4681 gcctgttgcg ataagatttc aacgacttgc tccttatttc gtttatctaa tgatccagtt
     4741 ggttcatcgg ctaaaatgat tttgctattc ttcaataaga ctctcgcaca ggcgattctt
     4801 tgcttctcac caccagataa tgtgtagata ggcgtactta gcttcttgtt tatatttact
     4861 tttttcaatg cctcatactt tgctgttcgc ttatctgaaa catttaaatt cgaaaacttc
     4921 aatccaatat ctaaattaaa atcgattgtt tcatattcaa tcaacccaaa atcttgaaaa
     4981 agaaaagaga gggcatttct ttttatcaag cgcttctctc ttccagttaa atgttttgtt
     5041 tcttgattaa ataaataaaa ttgccctgaa ctgaattgat cattcaatcc taatatattc
     5101 aataaagtac ttttccctgc tccgctctct ccaactacag tcacaaaatc cccagcatcc
     5161 gcagtgaaac gatccaaatg aagaatcgtt ttgtttcgaa tgattttttt cgcacctttt
     5221 atcactatca acggctccaa ttgttaacct ccattcatca gcaataactg acttttcttt
     5281 tctgtagaca aaataaaaac aactgaaaga ataaaatcaa tgaagctaaa gaaaaaaata
     5341 ttaaaaagat atttaggctc tctttctata agaaaaagga agattacact tgtcgttccc
     5401 catttgatga ggttcatcat gaagaaatct ttatacgttt caaagagcga ataaccactt
     5461 gaacgaaaga tagcgatttt ccgacaattg tagacaaaat atatgcataa catgacatag
     5521 ctcaacaaga agaaagaaaa gaaagtgagt aaaaatatct gtatcaagta atgaaatgat
     5581 ctgcttaaca ctttgacagc tatctcttca gtctgagtat acggaaatga taactgcaag
     5641 ttatcacgta actgactttc ttcaatcagc tcaaataacc tttctttcga caaagagcct
     5701 atcttgatct ttaacggtgg atagatttct ccgctgagaa tatttctttc ccaatacgta
     5761 ctgtttttca atgtcagtat ttcaacaacc ggataatgtt cgatccaggg gatagaagga
     5821 ataaatgtat aaatgggttg attgtttttt ataaatagaa atttcggttc tttttcactg
     5881 atttcttgat aatattctgt tatttgcgcc aggtcatttt ttaaatctgt atgtctatat
     5941 cgttcaggga tcaatataac agggtgcgtt tctttttcgg ttatttggat caaccttcca
     6001 gagacatcaa tcaaaggaaa tttcttaaga taattcagat ttatttttat ccctctgcca
     6061 aactgttcat tttcttcatt caagtaatct gatacattga ctaatatact tccgttttta
     6121 ttcaaagttt catataattc ctgatcggct gctgatgcaa aacgattgga ataaataaaa
     6181 tccacgtggt ttttcccgat ggttactgga taaaatacat gatagtcctc accagcgatt
     6241 tcttttggtg tttcatggga aacagctaac tgtgaagaag aaaaaacgat agttgctaat
     6301 tcgacattgg caacggtcaa aagaagagaa aacaacaatc caaatgtaaa aagaatgtat
     6361 tggatatagt tgaacgcttc tcttaacgaa gcgatttttt caactaataa aagagaaatc
     6421 aaagagatac cctatattcc gctgaacaag aaaacgtaca tctggaacaa ataaagaaat
     6481 tgctccttat aatacataaa aataaaacca ccaatgattc ctgcaattat gaatgtaata
     6541 atgattttct ttttccccaa taaacaccac aatacttgat gtaatgaaaa gccattattc
     6601 aacaataaac tgatttcttt attcatcaat aagaaaaagg atgataacaa aaggaataaa
     6661 agaatcaatc caatagttaa atacactcga taattatata cgtctgtact tgaaataacc
     6721 gaatacgaat agctattttc aaagtcttca aaaatattag tggcataatc agtgtgaaat
     6781 gcttgattga atcgttccac aaatagtaaa atgaaccgtt cataggcttc tttttctctc
     6841 gtcatcaaga aaaattcacc ttcaaaatct tttattttga tcgattcttc aatggacgtt
     6901 acgcgaaagg aggtattaga atagggtacc ttctcgtgag aagatttgac atccccttga
     6961 taatacaatg tcatttcaag ctttggctgt atcttgaagt tccaagatgt atctacttca
     7021 ttggattcat ttactgtttt tttcatataa gaaagctcag tttctgatga gacattttca
     7081 aataccatga ttagctgctc atattcttct tgcccaataa aatgttgtgg caatcgaatc
     7141 ggagtataag tatctgtttg atggaaaaat tcatttgtcc gatagagtac ctgtttattt
     7201 ataataacca aggcaaaacc actcatgata ccggtcacta tgattgtgag taaaactgtg
     7261 aacttttttt tgattatcac cactctccct tacttaaatg attctttgat aaaatcatac
     7321 cgtttttcat caaaaaaacg tatctatcaa atgtataggt catgtagaat aaatctatat
     7381 actgtagaat cgaaaggaga agaagatgaa catcggagaa aaaatacgaa cttaccgcag
     7441 aaattgtaag cttacgcaaa aagaattagg cgaaaaaatc ggtgtttccg ataaaacaat
     7501 ctctagttgg gaaaattctc gtacaatgcc agaccttgaa atgctgtcac ttttacatca
     7561 gactttaggt ctgccgattg attttccttc tattgaatca gctaccgaat caatagaacc
     7621 aacattgccg gatgaacctc ttgttatcaa gaaatcttat tcatcaaaac aacccttctc
     7681 actcaaaaag acactatctt tctttctgct cgtcttttgt ttggtctatc tttttcttat
     7741 caattatcaa tataaaaatg aaacggttga tcgattcaat ccttttttga aaccacaaat
     7801 cggctatacc acactccctg taggatacgt ggaaaattcc atcgaacatt gggtatgtaa
     7861 tgatatcttt gttcatggta catggctgtc ttttcacgct ggagaggtag aaaaaggtaa
     7921 gaatcatgct gtaatcaaac acaaaggaaa acacgtcatg aacgttcgcc tgctcacttg
     7981 ggaagccatt ccctcagatt accaagaaat cctcatccaa gactatgacg atgccttaaa
     8041 aagaagccct caggagccag ataggcatta agtaggagat gaacgtagag atagaaaaaa
     8101 tcaatgcaca tgatcttatc aaaaaaaaac aggggtacaa attaattgaa aaagctttga
     8161 gatgaaagtt cctaaataaa aaagttcaga atgataggta aaaaaatgac taactattct
     8221 agtattaggc tatttgtatt attcttctgt tatttttata tcaaaaaatc cagaaataac
     8281 taaatatagg tatttctggc ttatagtata atatttacgc cacagccccc aatgattctt
     8341 tttggaatca tgatcaagga cggacataca caaaaatatt ttgcccattc gatccgaata
     8401 gattaacgac taatctagta agtaatatag attggtacgt agtcaaacca gcaaatggaa
     8461 aagttgtcta ttccacccca agggctttaa agacagcatc ttccggcgtt tgataaaaaa
     8521 tcaaattaaa ggtacccatt aattctgggg gtacagttcc aatatcagca gcgcttatca
     8581 taggtacaag tacttttttc gctccggcat cttttgctac ttgtaaacag ttagctaaat
     8641 tatctacctt aatcatagaa ccaccaattg taatatcccc taaaataact aaacttggta
     8701 atacaggttt atttaaggaa actgagcata aagctattat agttgataac gataatgttt
     8761 ttgtcatacc aatgccattc atatcttgaa catgaacgac aaaatctttt gtcgtcaaac
     8821 taatagactg actaacactt ccataattag ctcttaaata tcggtatgcc gaatccatcg
     8881 cttctcttgc tccagcatct gaattgatcc cagtacgttc aaactttcca tttcccgaag
     8941 tcatttgcgt ttccaattta taggtaccta attgcccagt tttgccataa gataccgtgt
     9001 acaaatgccc tggcttccct aacccttctg gaatcaaagt tcctccacct tgttcaggaa
     9061 cagaaacata ctcttctcgc tcttcttcta aatcaatgta tgaaaaattg acatcataaa
     9121 attccattcc accaattttc tttaattgtt cttttacacg acgacgcatt tcaagagcaa
     9181 atcttagtat ttcttcgaca tcactttttt caaatctacc atcaggatac aacagtttca
     9241 tcatcccaga tacaatccga cgaactgcaa tcgtatcccg ctgatttaat tgagaaccaa
     9301 gtttgaaata tttatcaaaa ctatcgccaa aactaacttt tcgaagctca cgcatgactt
     9361 cagaaaaata atctgtaatg aagccatagt catttgtaaa aaaatctggt cgatatttag
     9421 gaatttccca acctggtaaa taacaatgca tccgatccaa aaaggctgaa tccgtcccca
     9481 taacctccgg aaatggctca aataaattcg aagttttcaa tattacatca acgctttgat
     9541 taatatttcc tacaaaagcc attgatgctg aagcattctt ttcttctttg cctctagcaa
     9601 aagatcctga agccatgtaa tctttcatga tttgaacgcc atcattatcc ttaaatttaa
     9661 tcccagcaac ttcgtcaaaa gcaacacagt cccacatacc tacaagtccc attgtacgac
     9721 tagccatatt atagaaaagg tttgctactg ttgtttgtcc acctgaaaca aggattgagt
     9781 ttggtgaaat ttctttatat acatgcgatt tacctgtacc acgtggtcct agttcacaga
     9841 gattaaaatt attttcaatt aatggaataa gtcttgctaa atgaagccat tttacccttt
     9901 tattaaattg tgtaggttcc ataccaatgg accgtagaag taagtcaatc cattcatttg
     9961 tagtaaactc cttgcgagcc atcttgtaag cctcaatgtc taaaccaggc atttggattg
    10021 gatcaacctt ttttgcaata aaagggctat tccaacgatc attctcatca taccaatatt
    10081 ccatcgaaac aatacaccag atccccccac ctaataatcg atcaaatttt ttcggatact
    10141 cttcactaat ttgaacattt tttaatccca ggttagagaa ttctgcttca taacaatctt
    10201 tcttttcatt taaatgtaca gttactttat caataactgt ataaccaccc aattcacgaa
    10261 tttttgcttt tactttttct gcttcatcag gacgcacata gtttcgagca agaatatttt
    10321 taacattttc cacacctttt tcaaccaatg tttcatccaa tgacgaagca tacataccaa
    10381 gtaaatattc caatacataa acaggtacat tcgcaccttc tttaattttc tttgttaaat
    10441 cttttctgac aatctttccg ggaaagaatt cagataactt taaaatttcc tgttgttcca
    10501 ctagaattcc tccatgtgtt cagtcattat aatagcaatt aaagtatatc atacttaacc
    10561 agtaggcttg ataatacaaa agaaaaagta tccacaaaaa attgtggata cctcgttttt
    10621 atatatcaaa atcaaatgat tctgcaaaag gattatctat aatgaatttt attcgctcgg
    10681 tcaaatcatt tttttgattt tttatcacta aataataagt atcttcaact gtatatcgac
    10741 gatttacaaa ttcaaaaaca aatttagtaa accgctgatt tgcatcttct gtttttgaat
    10801 ccgcaacata gatttcttca tttgagatac gttcaccata ttcatcttca aaataaagcc
    10861 agaaagatgc ggggtcataa acatcactaa ttgcattttt ttgatagaat tctaacgtgg
    10921 ttgataatcc tgtaattctg cggttgctag tcattaattc aattgctact ggttcctttg
    10981 cattgctacc tttggctacc gtaatttcta gaacagggac tagcatttct tgaatagatg
    11041 accctccatg aacgtagctt tgtcccccgc cagctttctt aaaaatactt gaagtaatcg
    11101 ggacacaaat gtttctagtg tcatcatttc ctaaagaatc tcccaaagag taatttttcg
    11161 taccaattat ttcgtattct tcttcactaa gaataaaacg acgttctaca cgatcttttt
    11221 catttctaga tggattttca atcttatcta cttcttcaac gtggcttctt ttataaataa
    11281 atccatgatc agccgtaact ataaaacgat agatactgcc atcattatgc aagcgattaa
    11341 taagtcggga aatttcgctt atcgctaaat cacaggcctc aaaaactcga ttttcattcg
    11401 agtgatcacc tgttctatcc acttgatcgt gataaatata aatgactgat ttgccattaa
    11461 atacttctcg tacctcagcc ttattcatct taaccacatc atcataattt aaagctacag
    11521 catttgcatc tcgttgctgg agaatcgcat ttcgattgga taaaccattc gtttttttcc
    11581 catcaatcag tacttctgtt ccttcattgt aagttagttg attgtttggt aataaggcgg
    11641 ctttaccgaa ttcagtaact gaaggtaata cagaaagaaa gctagccatg tttgttgaat
    11701 acttcttttc tctaactaac ttacgttcta aattcatccc taactcatat cgaaaagcat
    11761 ctgaaataat aactacagtt ttaacagagc gtttcattac agcttgatta taaaattttc
    11821 gaatggatgg acgattctta aattcaaaag tttgattcca aatttgtcct gattgatcaa
    11881 gaaacttcga ataatttgct tcaactaatc gatacaattg gccatatttt tgcttttctt
    11941 ctatatgatc actattccaa ataaatttcc gataatgcgt atcaacccaa tacatttcct
    12001 tctcatattg agttagcaaa ttatccatgt tcatcggcaa gcacaatctg tttttatcca
    12061 caagataata agcatgtttc aataattgat actcataaat ataatccgat gcgaaatgca
    12121 ttttttcgcg ctgctttaaa ctatcaaaaa ttgtttgtcc tgcaattttc gttgtagtgt
    12181 cagaagcctt taatcgttct gcataaaaca ttaatatttt tgcatgaatc tcagaaaata
    12241 cgtctgcttc aattagatca tcaatttcta tactgtctaa taatccatca ccatcaatag
    12301 cctgatatac ttttttagat agctgttcaa agctttccat gtaacgtgta tcattcataa
    12361 actgatccat gaaagtaata atgtttgctt tcaaatgtag tatttcaaat cctttgaact
    12421 tcttcggcat ctcttgatca atttgataat aaaaatagtt caaataaaga cacatcgtca
    12481 gcttttccaa tgttggctgg ctatccgtaa agccaaattt catttgaata aattcccaaa
    12541 atttagctgt taactgatac ttatcaagtt cccttaaagg attctcccta ctttctgtaa
    12601 agctttttag aactacacgc agtaaatcat ttaatcgaat acttttcgat ttcaacaaaa
    12661 cagccattat cattaattca atcgtttctg atttattaat tgtcatatgc gtactaaatt
    12721 caccaaaact tctcatgcga tcctttgcat taaagaaatt acgatactgt ttaactgtct
    12781 gatgaaatct aagtggaata gccaattcat tcatgataat cgctaagcgg tctgcactaa
    12841 attcctctga ataattcaat acactcaaca aatgattatc ttcatcttta tcatcccaac
    12901 gaggaaatgg cgcatagatt aaatagttag tttcgggatc ttcatattcc aataaacgct
    12961 tagttttaaa ttgtgcgtcc ttttctaatc gatagatttt tgcattttga atgaccaatg
    13021 agtcaatttc ttcaagaaaa tcctgatttg aatcaaacca aaaaatgatt ttcctacatc
    13081 cataattagg aaaacgttga tttaattttt cttcaatttg ttgcgtattt atatctgtca
    13141 tcaatctcac ctaatcgttc tctttctata ccccttatat tgacataatt tggataattt
    13201 cgcacgcaat ttaagaataa aaaagaaagt tgttagaaaa caactttctt agataactat
    13261 ttttttggtt ctttgacccc ttttgcaaaa atttggaatt tctcgccggt tttaggatca
    13321 cgctgcaact tatcataatt gacaattaca ccatcatcta agtctaattc aattcgtttt
    13381 aatgctaagt gacccaactt ctcgtcatac tcacgaactt cttttaattg cttctgaatc
    13441 tttacaattt cttttgtcat tgcatttctt tcttttgggt tatcacttgt tgaaatttgt
    13501 tgctgacgca attcgattcg attgtcatac gctttttgta gttcgtgtag gtattcagta
    13561 cgtacttttc ctaattgatc tggtgtatag cgatgcaagt acattaacgc tttaaagcca
    13621 ttttgttttc ctgagtccaa ttgccaataa attggtcgat tggagtatgt ttttaaatgg
    13681 tctttgtaaa aatcttgtac gaagtaacga cgaataattt ctcgacttgt ccctttgcca
    13741 cctaaagtgt cagcgataaa ctggagattt tcttcaaggg tttctttacc aaaagtaatc
    13801 tcaacgaaat caatgaaacg attgacaatg tcaatttggc tatccttgaa atactcatca
    13861 tcggtgatga gtaaaacatt atcagtatca ggtttaaatt tttgatagcg ggaaggatcc
    13921 cattcgccgc cagcgaagat gagaccatct tcgtctaggg agtaacgacc gaagatacaa
    13981 cctattgaat aagaaataaa atccttaatt tccctcgcct tatcaggtaa ccttgcagag
    14041 atatattcat cttgaacctc ttttgttaat tctttttcaa gagaataatg attaatgaat
    14101 atgtcgttca gttcctcttc attcgatttt agagtattaa attgattaac caactgccta
    14161 cttagacagt taaatgcctc tgagagatct tttttaaaca tataacttaa caaaatgttt
    14221 cttctaaact cgtatgacgt ttcaagagca ttatagtctt ttctagctat atcgatattt
    14281 tcatccactt tttctcttat tttttttaat tttctctcag atgtaacttt aagaaaaggt
    14341 agttttccca ttggtccttc atggtaatcc aaggtgggag aaataaaagt taaaaagtga
    14401 ttaactaatt tagagtttac atagccaaat atttcttcaa agtcagttat atcctttgag
    14461 aacagaacag atcctttagt ttcaaaaatt gcctgattct gcaatctaaa agatacttgt
    14521 ccagatgaaa gtgtcgacca agtaattccc tttttaaaat agtaattaag attttgtggt
    14581 ctagatttta acttcccatt ttcattaaca taatttttta tttcatctcc atcattctcc
    14641 cagttaacca cgtattcatt gtttccatac cattttctaa aacgaccacc tttagttgta
    14701 ggaaaccatt tttttctaga ctttttagcg tcctctaatg ttttagcatc aaactttatt
    14761 ttgttaaatt ctacttcaaa ccaataccgc aaaaatttat tgttatttcc ggttgccaac
    14821 ccttgttttg catctgcaac atcgttagtt aattttcctt gagcaaaatc agtgattacg
    14881 ttatcgcttg cccagtaagc aatcggcatt cctgggattt ttttgaagtt gtcttgatta
    14941 gtactataaa aataatcgca ttcaccatgc tgatgaattg cttctaacgt tttaattttt
    15001 tgaacttcca ttccaccttt aaaatctgat aattttatat agcttccatc ttgttcattt
    15061 gaatttttta tcgtaaacgt acaaattgga acggttgctt cttcaaaagc tgaatactcc
    15121 atttgaatca aactagaaat gtttctttca ttaattaaaa atgagcgtaa cttttcatag
    15181 ctagaaatga acatccaaac aaatggcgtc ataaaggaag catatccatt atcaatcagc
    15241 atttggctat tcaatttaat aaacacagaa aatagatctt ttttgacatc agaatagtta
    15301 tcatttacat atttttttaa tttcttatcc attttattaa gataaggcgg attagtgact
    15361 accgctacat atttatcaac tagcatttca gccacgtcaa gaatgtgcaa gtatttttct
    15421 tgtatttcct tcatcccata aagaatatcc atattcgtaa attcgttgaa ttttgatata
    15481 tactctctta cttttcctaa gtattcttta gttattgcct gattattttt atcgactaac
    15541 ttaatgattg atccaagttc tttcccattt tcaaattgat caaaaattaa ctctttgtat
    15601 tcattccagc gttcactata cttatcattg ttcaattcac taatacgctc ttgatactcg
    15661 tctgtcactt taggagaatc aataaactct cttaaattcg gcgatagact ttttttcaaa
    15721 aaaagacgat cgtattgacg ccctttcatc ataattgcaa aataagacaa ttgatacgct
    15781 cttttatcga tttcaagacc atataaattg tattcaacga ttgcacgtgc agcatcacgc
    15841 tcagaatatc ctaacgtaag ataaatttcc atcaatacat cgaaggcgta aactaaaata
    15901 tgcccagacc ccattgcgtt atcgataatt tttagttctt ctggttttaa attacttaca
    15961 gatgttgctt gttcaaaagc atatttatct ggaattaagt atttcaactt atttcttaat
    16021 tcactattgg gataatgatc taaccaatac tttcctaaac tattgtcaac catataacga
    16081 acgacccaat ctgtggtaaa tagttgagtt gctgccggaa tatcttgttt tttgacaatc
    16141 cctttataaa tattcaccac ttgattatgt ggctcactat tatagtactg atacaaccac
    16201 ccaataatct ctacctgtcc accagcttga acatagaaat catcctctgg aatacttaaa
    16261 agatcagcga ttacaccatc ttttttaata taagaagctg taaacaaaag ttctgtataa
    16321 tcttctactt cttcaaatag ctcaggtaag taatcattca attgattaca gatttttata
    16381 aaaatcaatt gatacagctt gtccattgct tctgctgaat tatctgtttt ccaagttctg
    16441 acttgttgct gttcattact agataattct tcaaagatat cggcatcata aatatctgta
    16501 ataatatctg gctcaatttt cccacttatt tcactagata atacacgata cgtgtcaggt
    16561 aaataatcat ttacctccat aaaccgaatg gcaatcaatc ggttaaacca cgtataagca
    16621 acctcttcga ttaactcttg aaaagcttct gaataagaag tgacagaagc acgttgtttt
    16681 agttctgcaa tcaatttgtt tctttgcgct atttcttttc cttgaattct tattcctgat
    16741 ttttcgattt cttgtaaatt gctatcaatt ttcttcacat cttcaatttt tgattcatca
    16801 attcctaaac gttttgcttt agtcattact tcatcaatta attttctacg ggcattgacc
    16861 gcgaaattct ttatcgcttt cttatccatt tttctttccc ttctatatgt aacctttgaa
    16921 aagacaggca cctttttatg cctgtctttt cactagaatt gaatcgtgat ttctgtattt
    16981 tcttgaagtt gttccttcag tttttgatta atttcagctg ttaactcatc aatatctgct
    17041 gctgacttaa tagttttaac atgaacgtta agtgttctca ttggtactgt tttctgttga
    17101 atagtaggtt ttactatcgc tatttcttca gcttttgctg cagagtctat ttcatctttt
    17161 tcagtttcac gaatcaagtt tgctgcttca atttgtttac gtgcttgttc ttcttgacgt
    17221 ctgcggtttt cttcattatc gaaacgttga ttaaagatca aatactgttc tgctacgttt
    17281 aatgataaga aaacaagatc atctatagta ttcgcttgtt caatttttgc tttcagttct
    17341 tgaaattctt ggtcaactat tggtacaaat tgatccttaa aatcttttcc ttctaataat
    17401 ttaaatgttg cttgtttttc ttccgttaat ttatttaata tttcctgact ttccaactct
    17461 aacagttgat tatattgttc aataaattct tgaatcaact catttagttt catcatatct
    17521 gaataaggat cagccttttt caaaatggtt ttcatctcat gaatcaattg atcaatttct
    17581 tggctagaag tttgacgccg acttttttcg attaatctaa ttttatcttg tgcattctcc
    17641 cagatttttt tctgagtact attttgcttg tggaaatttt taattttatc atatgtttca
    17701 gcccagtcga ataattcatc gcgatatttt ttgattgtat aaaaaaagtc ttcaacatct
    17761 gacgtttgaa caattacttc aagatatttt tttatttgct catattcata agcactaggg
    17821 taggtataag tgttttgtaa atcaaaataa gagcgtaaat tgtctaattg accttttaaa
    17881 tatttcttga aattttccat tgtatgttca ttgttatttt catcaacaat attacgactt
    17941 tgaaacagtt ctctaccgat ttcgtcaacc aatttttttg cttttggcga aatcaccgcg
    18001 cttggttcaa tttttatctt ttcactttct cgtcgttttt gaataatcat tacaatacta
    18061 tttggatcat ccatccgtga aatttgtaca ttgttataaa gtaaatcaat tttaccagac
    18121 atgaaaagtt tagcgatgca ccattccaca tcaagttctg tgaatccata cggttgtttt
    18181 gtttcaaaac gatcacgaat tgttttcatc gtaatcgtta ggtgatttct cttttgatca
    18241 ttgataaaat tgaaaatttc ctgaactgct tgctcatttg atggatcttc aataatttca
    18301 tttttgcttt ctttcactaa atataagata tcttcttttt ctttaggcgc atcaatttgg
    18361 tttaatttat ggtatacttc ttcagccatt ttctgaagtg ctgattggaa ttttgcttta
    18421 aagtcggagc ctgtcagttg aatttctgca ccgttataga aaaattttgc agatttcaac
    18481 agttcattta attgatcgtt gatacttgca cttagttcct gtaattcacc agatttttcc
    18541 gaacgaatcg cgtcaaagtt ctttactaca ctcgaataag tcgttgttaa ataaagattc
    18601 attctagcat acattgctat atcatcttta aattctttat ctgatggcaa ttctacgaat
    18661 aataagttac gggaactctt aagcgcaagt tctgcctctt gacctgctaa atcagagtat
    18721 ggtgaaataa aattaactgt catttcagca tttccagctt gcttgtatgg acgttgatct
    18781 aacacttgtg cataagtaaa cgtataccgg tttttaaatt tatttccacc tgacatgcct
    18841 aatttttcat aggcaaaact atttcggtct agaacgccgt caaaaattcg tttagatagt
    18901 tctacgatca aatcactatc tgtaatattt tgatttttaa tctcacgagt aatttcctgt
    18961 tcttcatcag tttggaaaat ataactatct aagttcttcc gcacaaagtt ttccttaatt
    19021 aaaaggtcca atgcttcttc tactcgtttt ttagtttcca ggcggtcttc gttgatattt
    19081 cttatcatca agctcgtaat attttcaaca tttggtttga tggcttgatc aacatattta
    19141 atcatgaata aaattcgtaa gacatttacg ttaaagttat ctatatcagt tggtctttga
    19201 atatgagaat tatttgtagc ttgtgtaatc actcggctaa ttgctgtatc aatccaacgt
    19261 tctaacgagt aataaaactg atctaaagaa accaaactgg ttgtatcatt ttccttattt
    19321 cgttcagcgg cttctttaaa cattgctagt aatgaacgtt caccagacga taagtttgat
    19381 ccttgatagc tgtgattacg aatctcggtt agaatttgcc ccaataaatt gaattgatag
    19441 ggaataaatg gataaacttc tgcgtaattt tcagcatctt ggaagagctt taattcagga
    19501 ctatcaacaa agagtaattt atttttcaat tctgtttgaa cagtttcaaa ttgtaaggct
    19561 aaagaatcat tggcaaactc ttttttcttc aaaatacgtt ctttaattac ttcatcggca
    19621 tttgctgaag ataaactcac agttgtggca aaacgatcct tgatcttaga aaaatcatta
    19681 tcagaattgt tatcaaagtt tgttacgtga tcaatcgctt cctgacttgt cactaatacc
    19741 caagccttac cttcacaaat tcgacccaaa tcttccacaa cggtttgtaa ctgcaaagtc
    19801 aactcacgat taccgccgat atattgtccg acctcatcga ctagaaaggc aatatgatgg
    19861 tctgcttctt tggaatcaag atagctttta actagatttg caaagtcatc aatgcttatt
    19921 aaataatttc ctgatgcttt ttctaaaaaa ttatcaatag cggcttcact cataaaatcg
    19981 attttaagtg ccgcttcttt gatatcatct tggatccaat caaactcatg gcgctcttct
    20041 tgccattttg ccccattaat ctcttcaaaa gcagctttga atgcatcaaa cttttcttct
    20101 ttaattaacc gacgttcaaa atctgctaga tgtggaatcg tgcttaatcc ttgcatttcg
    20161 ttaaatacct ttaaaaaaac attcacgatt ccgtttttgt cttttttacc acctgcatca
    20221 ctttttgaat caatattaaa cagaataaca tctgtattta tttgtgagca ccgttccatc
    20281 gttgccaaag tcagtggatc tttgattttc ccatcttctt tgaagtaatc aatggctttc
    20341 ttgtcattta tttctcgatt tgcgagcaag taagaaataa tttttaagaa atgagattta
    20401 cctgaaccaa agaacccctg aatccaaaca cccattttat ctgttggtgt attgatactc
    20461 cgttggtagg catcaaaaat tgttttaaag tgtttttgta gttctttcgt aaccacgtat
    20521 tcttctaatt cttgttgaac attttcatcc tttgcttgac cgaccttaat aactccttga
    20581 atatttcggt caattggttt tgcaaaaata tctttaatta gcatttaatc tcctaccttc
    20641 catcccaact aaattctaaa tgctcgataa taattatcat ctttattggt attaagaatt
    20701 gtcaaactta attcatcata ttcccctgga tacatcatca caactggtac gcgatcaaat
    20761 acctgatgca ttttatttaa aatagagtgc gctctaatta atggatataa ttcgccaatt
    20821 cctgtcagga acacaactga tttttctggt gtatgggcat ccacatattc aaaaaataca
    20881 ttttcttcct caggtaaatc cattttcaat aaacgaccaa tgctttccac taatttttgt
    20941 aaaccacgtc gttcttccat cttaatcgct ttttcagtga aaccgcgttt ttctagatac
    21001 tctaacataa tcacatagag attataaact ttcacttcat aattatcacc aacagatgtt
    21061 ccagatatat cattaatata atctcttaca attaactcgt ctttcggatc gtagtcaaag
    21121 atataatagc ctacttcatt acctaaacca cgattcaata aaaaatcttc tttttgaatt
    21181 acttcattca acttttccaa atgctcttga atcgataatg acattataaa attcctccca
    21241 gtgctagtac aatatcttta cgattcttgt caactaacca ttgaatcaat cgtttatcta
    21301 ataatatcgg agtcattcgt ccatattctt tttcccctct gactaatcct gtttcaatta
    21361 gattcgtttg ataagcggca ataagccgtt taatcgtata atctttccat tttgaaatat
    21421 cttctgaact tctccgcttc tctgtaaaaa aagaacggta atcaactggt gttaattgca
    21481 aatttccttt acgtagattt tcagcatata cctcagtcat aaattcatta aaaagatcat
    21541 caatcataag gatggaaatc aaattcacta acttttgatt atctatattt aactgattga
    21601 aaagttgcaa tccagcttca tccagttgac taactctcct tttcacgttc tgatagattt
    21661 ctttttgacg gttactgctc actgcaaaaa aaatattttc atgttcattt ttctctttaa
    21721 tttctatatc tgtatatcct tctagtcgta attgaatata taacttgaac tctgaaaacc
    21781 aaaagcgttt agaaactaga ccagcagaat attttttatt caatagattg cctcctaatc
    21841 atctataatt caataagtaa acaagtgttt tttgctcatc gttagcattc attttttagt
    21901 atctactata caatacatat ttattatag
//
LOCUS       DBBGRF010000051        20664 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000051 DBBGRF010000000
VERSION     DBBGRF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.051"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            168..362
                     /locus_tag="ACIZD4_002171"
     CDS             168..362
                     /locus_tag="ACIZD4_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991075.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="ACIZD4_002172"
     CDS             631..930
                     /locus_tag="ACIZD4_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991076.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="ACIZD4_002173"
     CDS             complement(1027..1461)
                     /locus_tag="ACIZD4_002173"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991077.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="ACIZD4_002174"
     CDS             complement(1693..2403)
                     /locus_tag="ACIZD4_002174"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGC5991078.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="ACIZD4_002175"
     CDS             complement(2393..3253)
                     /locus_tag="ACIZD4_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGC5991079.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="ACIZD4_002176"
     CDS             complement(3258..3896)
                     /locus_tag="ACIZD4_002176"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGC5991080.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="ACIZD4_002177"
     CDS             complement(3911..4210)
                     /locus_tag="ACIZD4_002177"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC5991081.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="ACIZD4_002178"
     CDS             complement(4253..5737)
                     /locus_tag="ACIZD4_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGC5991082.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGVLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="ACIZD4_002179"
     CDS             complement(5757..6218)
                     /locus_tag="ACIZD4_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC5991083.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ACIZD4_002180"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ACIZD4_002180"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGC5991084.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="ACIZD4_002181"
     CDS             7521..8291
                     /locus_tag="ACIZD4_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGC5991085.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="ACIZD4_002182"
     CDS             complement(8564..9391)
                     /locus_tag="ACIZD4_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991086.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="ACIZD4_002183"
     CDS             9959..11194
                     /locus_tag="ACIZD4_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGC5991087.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="ACIZD4_002184"
     CDS             complement(12193..12453)
                     /locus_tag="ACIZD4_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HGC5991088.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="ACIZD4_002185"
     CDS             complement(12480..13781)
                     /locus_tag="ACIZD4_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC5991089.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="ACIZD4_002186"
     CDS             complement(14073..14531)
                     /locus_tag="ACIZD4_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGC5991090.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15875)
                     /locus_tag="ACIZD4_002187"
     CDS             complement(14544..15875)
                     /locus_tag="ACIZD4_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HGC5991091.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17328)
                     /locus_tag="ACIZD4_002188"
     CDS             complement(15886..17328)
                     /locus_tag="ACIZD4_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC5991092.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="ACIZD4_002189"
     CDS             complement(17315..18079)
                     /locus_tag="ACIZD4_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HGC5991093.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="ACIZD4_002190"
     CDS             complement(18183..19058)
                     /locus_tag="ACIZD4_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC5991094.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="ACIZD4_002191"
     tRNA            complement(19313..19397)
                     /locus_tag="ACIZD4_002191"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="ACIZD4_002192"
     tRNA            complement(19415..19486)
                     /locus_tag="ACIZD4_002192"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="ACIZD4_002193"
     tRNA            complement(19496..19568)
                     /locus_tag="ACIZD4_002193"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="ACIZD4_002194"
     tRNA            complement(19630..19714)
                     /locus_tag="ACIZD4_002194"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="ACIZD4_002195"
     tRNA            complement(19735..19805)
                     /locus_tag="ACIZD4_002195"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
     gene            complement(19851..19922)
                     /locus_tag="ACIZD4_002196"
     tRNA            complement(19851..19922)
                     /locus_tag="ACIZD4_002196"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19888..19890),aa:Gln,seq:ttg)
     gene            complement(19934..20006)
                     /locus_tag="ACIZD4_002197"
     tRNA            complement(19934..20006)
                     /locus_tag="ACIZD4_002197"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19971..19973),aa:His,seq:gtg)
     gene            complement(20009..20082)
                     /locus_tag="ACIZD4_002198"
     tRNA            complement(20009..20082)
                     /locus_tag="ACIZD4_002198"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20048..20050),aa:Trp,seq:cca)
     gene            complement(20089..20169)
                     /locus_tag="ACIZD4_002199"
     tRNA            complement(20089..20169)
                     /locus_tag="ACIZD4_002199"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20133..20135),aa:Tyr,seq:gta)
     gene            complement(20171..20246)
                     /locus_tag="ACIZD4_002200"
     tRNA            complement(20171..20246)
                     /locus_tag="ACIZD4_002200"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20211..20213),aa:Phe,seq:gaa)
     gene            complement(20282..20354)
                     /locus_tag="ACIZD4_002201"
     tRNA            complement(20282..20354)
                     /locus_tag="ACIZD4_002201"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20319..20321),aa:Asp,seq:gtc)
     gene            complement(20364..20436)
                     /locus_tag="ACIZD4_002202"
     tRNA            complement(20364..20436)
                     /locus_tag="ACIZD4_002202"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20401..20403),aa:Val,seq:tac)
     gene            complement(20452..20523)
                     /locus_tag="ACIZD4_002203"
     tRNA            complement(20452..20523)
                     /locus_tag="ACIZD4_002203"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20488..20490),aa:Glu,seq:ttc)
     gene            complement(20538..20627)
                     /locus_tag="ACIZD4_002204"
     tRNA            complement(20538..20627)
                     /locus_tag="ACIZD4_002204"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20591..20593),aa:Ser,seq:gga)
BASE COUNT         6532 a         4320 c         3273 g         6539 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagacccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccac cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaaaggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatagaaa ctggggtagc
    19861 tggattcgaa ccaacgcatg agggagtcaa agtcccttgc cttaccgctt ggctataccc
    19921 caagaataaa aagggcgaat gatgggaatc gaacccacga atgccggagc cacaatccgg
    19981 tgcgttaacc acttcgccac attcgccatg gcaggggcag caggaattga acccacacta
    20041 acggttttgg agaccgctgt tctaccttta aactatgccc ctataaaatg gaggagagtg
    20101 gattcgaacc actgaaccct aaggaacgga tttacagtcc gtcgcgttta gccacttcgc
    20161 tactcctcca tggtggcgcg ggacagaatc gaactgccga cacacggagc ttcaatccgt
    20221 tgctctacca actgagctac cgcgccatat tttaaaatta ttaattgaat aacaagaacg
    20281 acggttccga cgggaatcga acccgcgatc tcctgcgtga caggcaggca tgttaacccc
    20341 tacaccacgg aaccagttca ttatggaggt taacgggatc gaaccgctga ccctctgctt
    20401 gtaaggcaga tgctctccca gctgagctaa acctccaaca ttcaattaaa atgacccgta
    20461 cgggattcga acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg
    20521 gccaggtaaa tttgctacgg agagtaaggg attcgaaccc ttgagacagt ttggcaccat
    20581 ctacatgatt tccaatcatg ctccttcggc ctctcggaca actctccaga gtgaaagaag
    20641 ctcaatactc tttctcaaaa tgag
//
LOCUS       DBBGRF010000052        20360 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000052 DBBGRF010000000
VERSION     DBBGRF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.052"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            291..1430
                     /locus_tag="ACIZD4_002205"
     CDS             291..1430
                     /locus_tag="ACIZD4_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HGC5991095.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1497..2072)
                     /locus_tag="ACIZD4_002206"
     CDS             complement(1497..2072)
                     /locus_tag="ACIZD4_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC5991096.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2077..3051)
                     /locus_tag="ACIZD4_002207"
     CDS             complement(2077..3051)
                     /locus_tag="ACIZD4_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HGC5991097.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3075..3119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3334..4302
                     /locus_tag="ACIZD4_002208"
     CDS             3334..4302
                     /locus_tag="ACIZD4_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC5991098.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4415..4693
                     /locus_tag="ACIZD4_002209"
     CDS             4415..4693
                     /locus_tag="ACIZD4_002209"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991099.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4811..5047
                     /gene="secG"
                     /locus_tag="ACIZD4_002210"
     CDS             4811..5047
                     /gene="secG"
                     /locus_tag="ACIZD4_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGC5991100.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5150..5905
                     /locus_tag="ACIZD4_002211"
     CDS             5150..5905
                     /locus_tag="ACIZD4_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC5991101.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSL
                     AEHQLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5908..8265
                     /gene="rnr"
                     /locus_tag="ACIZD4_002212"
     CDS             5908..8265
                     /gene="rnr"
                     /locus_tag="ACIZD4_002212"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGC5991102.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8287..8751
                     /gene="smpB"
                     /locus_tag="ACIZD4_002213"
     CDS             8287..8751
                     /gene="smpB"
                     /locus_tag="ACIZD4_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGC5991103.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9053..9772
                     /gene="atpB"
                     /locus_tag="ACIZD4_002214"
     CDS             9053..9772
                     /gene="atpB"
                     /locus_tag="ACIZD4_002214"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGC5991104.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9825..10040
                     /gene="atpE"
                     /locus_tag="ACIZD4_002215"
     CDS             9825..10040
                     /gene="atpE"
                     /locus_tag="ACIZD4_002215"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HGC5991105.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10131..10655
                     /gene="atpF"
                     /locus_tag="ACIZD4_002216"
     CDS             10131..10655
                     /gene="atpF"
                     /locus_tag="ACIZD4_002216"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGC5991106.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10642..11184
                     /locus_tag="ACIZD4_002217"
     CDS             10642..11184
                     /locus_tag="ACIZD4_002217"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGC5991107.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11207..12763
                     /gene="atpA"
                     /locus_tag="ACIZD4_002218"
     CDS             11207..12763
                     /gene="atpA"
                     /locus_tag="ACIZD4_002218"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGC5991108.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12777..13679
                     /locus_tag="ACIZD4_002219"
     CDS             12777..13679
                     /locus_tag="ACIZD4_002219"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGC5991109.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13702..15108
                     /gene="atpD"
                     /locus_tag="ACIZD4_002220"
     CDS             13702..15108
                     /gene="atpD"
                     /locus_tag="ACIZD4_002220"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGC5991110.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15122..15544
                     /locus_tag="ACIZD4_002221"
     CDS             15122..15544
                     /locus_tag="ACIZD4_002221"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGC5991111.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16013..16243
                     /locus_tag="ACIZD4_002222"
     CDS             16013..16243
                     /locus_tag="ACIZD4_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGC5991112.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16340..17641
                     /gene="murA"
                     /locus_tag="ACIZD4_002223"
     CDS             16340..17641
                     /gene="murA"
                     /locus_tag="ACIZD4_002223"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGC5991113.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17654..17830
                     /locus_tag="ACIZD4_002224"
     CDS             17654..17830
                     /locus_tag="ACIZD4_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGC5991114.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17965..18261
                     /gene="yidD"
                     /locus_tag="ACIZD4_002225"
     CDS             17965..18261
                     /gene="yidD"
                     /locus_tag="ACIZD4_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGC5991115.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18325..18708
                     /locus_tag="ACIZD4_002226"
     CDS             18325..18708
                     /locus_tag="ACIZD4_002226"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991116.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18877..19761
                     /locus_tag="ACIZD4_002227"
     CDS             18877..19761
                     /locus_tag="ACIZD4_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGC5991117.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19875..20111
                     /locus_tag="ACIZD4_002228"
     CDS             19875..20111
                     /locus_tag="ACIZD4_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGC5991118.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20199..20279
                     /locus_tag="ACIZD4_002229"
     tRNA            20199..20279
                     /locus_tag="ACIZD4_002229"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20233..20235,aa:Tyr,seq:gta)
     gene            20286..20357
                     /locus_tag="ACIZD4_002230"
     tRNA            20286..20357
                     /locus_tag="ACIZD4_002230"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20318..20320,aa:Gln,seq:ttg)
BASE COUNT         6759 a         3566 c         4425 g         5610 t
ORIGIN      
        1 ttttttgcaa ctagcttctg tatatgatgt ttacaaagaa tggtacaaga aaagatcatc
       61 cttgaaaaag gaaagctaac aataactagc atcatataag agcttttaag gatagaacag
      121 tagaatagga atctatgggc aagtcctctc gtataaataa aataggaggg aagtagcagc
      181 atatttttca taaagtggct ctctttcttc atttttactt tggttgctcc tatttgaaaa
      241 ttcgagcaca ctcaaataca ataaaaagaa atggcaaggg agaggattag atgaaaaaag
      301 aagaaaaaat cgcgatttta caagagatta tccgaattaa atcagtgaat ggaaacgaag
      361 gtgaagtagc agcctatttg aataagcttt tggcaaggca tgacataaca ggagagattg
      421 tttcttacag agatggtaga gataatttga ttgctcgtta ccaaaagggc caatcaggaa
      481 aagtgttagg cctatctgga catatggatg tcgtggcggc tggtgatgaa tcgtcttgga
      541 cctatgcacc ctttgcagca gaaatccatg ggaaccgttt gtacggacgt ggtgctacag
      601 atatgaagag tggcttggca gcaatggtga ttgccatgat cgaactgaaa gagtcaggaa
      661 aaccatttaa cggaacagtc aaattattag ccactgtcgg agaagaagtg ggtgaactag
      721 gtggggaaca gctcacgaaa gcaggctatg tagatgactt agatgccttg atcatcggag
      781 agccaaccaa ttacagtttg atgtatacgc acatgggatc aatcaactat acagtcacct
      841 cgcacggaaa agaagcgcat agctctatgc cagaccaagg ttataatgca atcaatcacc
      901 taaatgaatt cattacgaaa gcaaatgctg aaatgaatca cctcgctgaa acaatcgaga
      961 atcctgtcct aggaaaaaca atccataatg ttacattgat cagtggcggg aatcaagtca
     1021 acagcatccc aagccatgcg cagctccaag ggaacattcg atcgattcca gaatacccaa
     1081 atgataaaat cattgcattg ctgcaatcaa tcgtcaatga attgaatcaa gagacagact
     1141 atcatttgga attgatgatc gattacaaca aaatacctgt caaagctgat ccagattctc
     1201 ctttgattca ttccattcag caacaattca gccagccatt acctttagtt ggagcggcag
     1261 caacaacgga tgcagccgaa tttacgaaag ctaaccattc cttcgacttt gtcgtctttg
     1321 ggcctggtgt cgttactttg cctcatcaag tagatgagta tgttgaaatc gataattatt
     1381 tggatatgat cgaaaaatat caaggaatta ttttatccta cttagcgtaa gattttttta
     1441 ataaatgaaa aaacagagcc agattagcat tattttgcta atccagctct gtttattcag
     1501 cctatttttc tttttgaata tatcaagcgt tggggcaaca tagtgatgac taatgaaaca
     1561 acgacgatag acaacaagcg atcaaggtag tctgtaccca cctgtaccaa gatcacactt
     1621 gttgtctgac ttaaacctaa cccatgtaat agctgaacga tcatactgga tcctgaggag
     1681 gtgatcccgc caaataactg aacggtaatg atcgaagaaa cgatcgttcc aggtaccgac
     1741 aaaatcaaag cgagtaataa cagtttcaag ctgtttttat ctttgccgag atatcttggc
     1801 aaaatcaatc cagcaagcaa gcctgtgaga atttggattg gcgaataata cagagaaaaa
     1861 atatctgtag tcactccact taaaataccg ctggacaatc ctgtcagcat tccaggtaca
     1921 ggcccaagca atgcaccagc aaaaatcgtt ccgatagaat cgagatagat tggcaaacga
     1981 agccataaag caatcgttcc tccaatataa ttgatcccaa tacacaaagc catcactgta
     2041 agtacgcgag ttgccatttt gtttttattc attttgttag cccatcttta acctttccaa
     2101 atctttcata atcgtttctt cttgtgcatt taaaagaacg gttaaaaact ttcggaaaaa
     2161 aagacgagta tctacttttg tcataatttt actgttagca ggtttctgcc aaaattcata
     2221 acgatcaacc aatgtttgtc cgcgacttat tccttgagtt tctacagcag tgaagctttt
     2281 aaagccttca cagatggact catcgataaa ataagcaaca gctaatggat cattgatgac
     2341 acatcctaag attctttctt gtttccagtg aaagtcaaaa taaaaacgag tgatcgcttt
     2401 tagatactct ccctcttcag gattcatttg gcagcaatat tcaaggatag tcggtgtcaa
     2461 gacgatttct cttgtcacat ctaacccaac catttctatc ggttgtttga gcttttcgaa
     2521 tacataagaa gctgcttcag gatcacacca gtaattgtat tcagcaactg gtgaacagtt
     2581 accatggctt ttgtaagttc cgcccattga gacaaaacga tccatatgtt tcccaacaga
     2641 tgggctgttt ttcaaagcag aagcgatatt ggtcaaaggc cccaaagcaa tgactgatgt
     2701 atctgttttt tctttgaaat aatcagtcag aaaatcaact gcatggagcg attctgcctg
     2761 tttggctaag accatcggga aatttgtgtc ccctaatcca tccaacccat gagtgtcttg
     2821 cgcactaatg aaaggttgct tcaaaggttt ttccattcct tgataaacag ggatatctaa
     2881 acgatcacag cgctccaaac atttcagcac attctgcgta ccgatatcta cagggacatt
     2941 cccgcaaacg acggtaatag caactacttc gatatcaggg gatttgacag ctagtgataa
     3001 agctaaagtg tcgtcgatcc ctggatcgca atcaataatt actttacgca ttatttccaa
     3061 tctcctttct ttagagatac ttagtttttt attctgggaa gtttccgaac cagtccaaga
     3121 cgagtgtctt gtttataatg cacgaaatta gtatactggc ttttattgtg aatgtaaatg
     3181 ctctcttaca agtaaatcta ttgagaagaa ctttaagtaa atgatacaat gaaaaagaaa
     3241 tggaatttac gtgtgccgaa gaaaaagaat cctattgatc ggtatattgt ataataaata
     3301 gattatagtt tggcagaaag cggcgggtgt acgatggtta ttttttattt cattcttatt
     3361 ctgatattta taggaatcag ttaccatttt ctttcttatt tttatgcaaa gaaattagta
     3421 agagcggggg tacagagagg ctatgactgg tatgaagaaa ctgggcaccg cttgatggat
     3481 cctgctgcag tcacgtcagt agaaaaaaag cgacaaaaat tagaagaaga gtgtgaaagc
     3541 ttctgggaac aaggaatacc gaaaacgatc aaaagttatg acgggttgaa actagctgga
     3601 cagatgttcc tccaaccaac tcagcagaat aaatgggtca tttgtgtaca tgattatcga
     3661 agtacaggga aaagagatat gtctcatata ggtaaaagat atgcagagaa aggattcaac
     3721 gttcttatac ccgatttacg tgcgcatgga gaaagtgaag gagaaatcat cggaatggga
     3781 tggctagacc ggctagattt aattgcatgg atccaactca tcttagatga acaaccagat
     3841 gcatccatta ttttgcacgg cagttcgatg ggcgcttcta ctattatgat ggcaagtggt
     3901 gaaaagcttc catctgcagt caaaggattt atcttagaca gcggatatgt ttctgtttat
     3961 gcggaatttc ggtatatgtt aagtaaaatc acggtctttc ctaaaaaaat gatcatgaga
     4021 tatgcgaatc actatgctca gaaatacgca ggttattctt taaagcaagc atcagctaca
     4081 agacagcttg gtagtaacca tttgcctttg ttagtcatcc atggtgaaag agatcatttt
     4141 gttcctacag aagcagcata cacgattcaa aacgctacgg caggggataa agcattactg
     4201 cttgttccag aagcagaaca tttggaagca tcgatgaaag atccgaaaac ctattggaca
     4261 gtgatttttt catttattga acaaagaata acgatggatt gattttctct tcctttttgt
     4321 aagcaacacg aggataaata attgtttata gaccatgaga ctgttaaaat aaggtaggaa
     4381 taaaaaaata tcagttattt gaggagtgcg gcatatggaa atcaaagagg aaaaaaatcg
     4441 tcttgcttta ttcaatgatg agcaacaaga aatcggagaa atgacatggt cggatgcggg
     4501 gccagacatc atgatcattg accatacatt tgtcgatcca gcatatcgtg gtcaaaaatt
     4561 agctgaaaag ctagtgtata ctggagtaga actagcaaga cgagagggga aaaagattat
     4621 cccttcatgc ccttacgcaa aaaaagagtt tgagaagaaa ccagagtatc atgacgtctt
     4681 acgccaatca taataataac agctgaaaga tttgcacttt cagctgtttt tccatttata
     4741 tagagttgtc acggagtttt atctatgata aagttaaaga gacgatatct tttgggaagg
     4801 aggctgctat atgtataatt taattttggg aatcgtgatc gttttatcga ttgttatggt
     4861 cattgcgatt atgatgcagc caagcaagca aaatagtgca gcgagtgcat ttaccggcgg
     4921 tgcggatcaa ctattcggca aacaaaaagc tcgcggcttt gaagctgtca tgcagcgatc
     4981 aactgcagtc atgggagctg tctggatgat cttattattt gtcctagcat ttttatcttc
     5041 gaagtagtcg aataagcctc tcgcacaacg gcgggcggct ttttttattg caaagagaac
     5101 gcttaagaag aagttatgaa agaaactatg gtaaaatgag gcgaaagagg tgaaacgagt
     5161 gaaacaatta ccaaaacccc tttatgcaaa acatggaaaa cgagcagttt tgctgcttca
     5221 tgcgtactca ggaagtccaa atgatgtccg gatgctcgca cggtttttag aaaaagcaga
     5281 ttatacagtc tatgcgccgc tatttaaagg acatggaacg atggagccat atgatatctt
     5341 gcaagaaaaa gcagaaagct ggtgggcaga tactaaaaaa gctatccatt ttttacagtc
     5401 tgaacagttt tctgatattg ccgtattggg attatcgatg ggtggcatct ttgctgtacg
     5461 ggcactagaa gaagaatcag taattggcgg cggttttttc tgttcgcccc tgtctcctgt
     5521 agaaacaaac gtgcctgaaa attttgaaaa atatgtacgt caagtgctga agatagcagg
     5581 caaatcagaa aaagaaatca atgaaaaagc tgtgtcttac cgctcgttag ctgaacatca
     5641 attaatggat atacaagacc aagcagcaat cgcagaaagt agactatcag atatccaaca
     5701 gccaatattt ttagctcaag ctgggaaaga tgaaatgatc gacccaaatg gtgtatttga
     5761 aacggcacgc aaattgagcc gccaacgagt gacacttcaa tggtatcctg aaagcggtca
     5821 tgtgattaca gttggcacag caagacgcga attagaaaaa gacgtgttgg aatttttaga
     5881 aaaattacct tggaatgagg aataaatatg acaaaagaaa caataaaaga gaaaattctc
     5941 tttttcatgg aaagcagtcg caaacgtagt ttttctatgg aagaaatcgc tgaaggtcta
     6001 ggctttcaaa aaagcgatga ttttaaatta ctagtacaaa cgattgctca aatggaaaga
     6061 gaacagagta tcgttttcaa taaaaaagga aaagtcaaac ttcctttaaa accgatcttg
     6121 gtcgaaggga catttcgggc aaatgaacga ggatttggat ttgtaacgat tgatcccgaa
     6181 gaagatgata tctatatccc gaaagaagcg actggctttg caatggatgg ggataccgta
     6241 gcaattgata tcatgaagcg agcaaataca gatatggatc gcggagcaga gggaaaagta
     6301 gtggagattc gagaccgagc gactactcag ttagccggag aatttgttgc ttattcagac
     6361 gaagagatac aggaaacgga tctttatggt gtggtcatcc cgaaagatag aaagcttaac
     6421 caattcaaag tgtatgcagc ggcagaggga gttcgtccag ttgacggaag tattgtattg
     6481 atcgaactga cccattaccc tgaaaaaggg tatgcaacta gtttagaagg gataatcaag
     6541 caagtgattg gtcataagaa tgaccctggc atggatatcc tctcgattgt cgtggctaac
     6601 ggtattccta caaaatttcc tgatgatgtg ttatctgagg cagatgaagt tccagaccag
     6661 atcagcgaaa aggatattgt tggacgcaga gatttaagag atcagctcat cgttacgatt
     6721 gatggagaag atgcaaaaga tctagatgat gcagtgacgg tcaaaaaatt agaaaatggt
     6781 aattattttc ttggagtaca cattgcagat gtatcttact atgtgacgca aggcagtcaa
     6841 ctggacagag aagcatacga aagaggaaca agtgtctatt tgaccgatcg agtgattccg
     6901 atgatcccac aacgtttatc caatggtatc tgttcattga atccccatgt tccacgactc
     6961 accatgagtt gtgaaatgga gatcgatcca aatggacaag ttgtctctca tgagattttt
     7021 ccaagtgtga tccaaacaac agaacggatg acctacacag ctgtcaatca aatcttagaa
     7081 gatcaagatg aagaaacgat gcaacgttat gctcagctcg tgcctatgtt ccaagaaatg
     7141 ggtgaattgc atcgaatcct tgaaatgatg cgaatcaaac gtggagcgat ttcttttgag
     7201 gatcgtgaag cgaagatcct tgttgatgct gaaggacacc caaatgatat ccagctaaga
     7261 agcagaggga taggtgaacg cttgatcgaa tcctttatgc ttgctgccaa cgaaacggta
     7321 gctgaacatt ataataaatt aaatcttccg tttatttatc gaatccatga acagccaaaa
     7381 gaagaaaaaa tgcagcgctt ctttgatttt gcttcagctt tgggcattct ggtccgagga
     7441 acgaaaggaa cgatcacacc aaaagattta cagcatgtga tcgaaggagt agaagacaaa
     7501 ccagaagctg cagttatcaa tactatgttg ctaagaagca tgcaacaagc acgctattca
     7561 gaagacaatt ttgggcatta tggcttagcg gcagattact acacacactt tacatctcct
     7621 attcgacgct atcccgatct aatcgtccat cgtctgatcc gttcttacag tgaagataaa
     7681 agtgaaagca atcaaagttc gtgggctgcg gaacttcctg aaattgcaga tcatagttct
     7741 aagatggaac gtcgtgcagt agaaacagaa cgtgaagtag attccatgaa gaaagcagaa
     7801 ttcatgatgg acaaagtggg agaagaattc gatgggatca tcagctctgt tgtgaaattc
     7861 ggcctgttta tcgaactgcc gaatacagta gaaggattga tccatatcaa tgaattgaaa
     7921 caggactact tccattttgt tgaaaatcat ttagctcttg taggtgaaag aactggtctg
     7981 acttttaaaa tcggacaaaa agtgcgcgta aaagtagtca aagctgatcc agatgaacga
     8041 gcagtggatt ttgaactcgt ttccgcagaa gaggtcactg cgttggaacg tccaaaagca
     8101 cgcaatggaa aatctggaaa acgagaagga aaacaagcag gcaaacgctc agaaaaaaat
     8161 ggcaagaaga acaaacgata tagtgatagt aagcaaacgt tcggtaagaa aaaagggaaa
     8221 aagccatttt acaaaggtgt caaaaagaag aaaaagaaaa aataaaatga gttggaggaa
     8281 acagctatgc caaaaggcga gggaaaacta attgcacaaa acaagaaagc tcgccatgat
     8341 tattcgatca tcgacacgat ggaagcaggg atggtcttgc aaggaacgga gatcaagtcg
     8401 atacgaaaca gccggatcaa tctgaaagat ggatttattc gcgtccgcaa cggggaagct
     8461 ttcttgcata atgttcatat cagtccttat gaacaaggaa atatttttaa tcatgatccg
     8521 ttgcgcacga gaaagttatt attacacaag aaacaaatcg ttcgtcttga aaacgaattg
     8581 aaaaacactg gaatcactgt tgttccttta aaagtctata ttcgtaacgg ctatgccaag
     8641 gtattgattg gtctggcaaa agggaaaaaa tcgtatgata aacgggaaga tttgaaacga
     8701 aaagatatcg atcgacaaat tgatcgaaca ttaaaaaatt tctctagata atttcattat
     8761 cctttttcgc atattcggtg cttttgcttt tacttaatga taaaatttgt tagcatttaa
     8821 tctgataaaa catgattatc acaggttttt tcttagatca ggagcaccgt gcatggggaa
     8881 aaattcgctt cgtttttgac tgaaataaaa aagtgtctaa ttttcatgaa aatgttttga
     8941 attttctgtt tcatggtggt atgataccgt gtggttagaa accgattgga aaaaaccaga
     9001 tacgcacatg aattgatttt atgtgaattt cggggaaaag aggtgaaatg gattggatga
     9061 acgctcgcta acgtttcaca ttggaccaat ttggtttgat ggtacagttt gtataatggt
     9121 gttactgacc tgtttgattg ttttcttctt agcttacttt tttacaagaa atcttaagtt
     9181 gaaaccaaca ggcaaacaaa atgcgataga atgggtcatt gattttagtc gaggaatcgt
     9241 aacagataat ctgcctagaa aagaattgag caatttccat ttgttggcat ttacattgtt
     9301 tttatttgtt tttgttgcaa acaacatagg tttagtaaca aaaatcgtct tacctaacga
     9361 aacaacactt tggaaaagcc cgacagcaga cccgtttgtt actttaactt tggcatttat
     9421 aatgatctta cttactcact tattcggggt gaaaaagtta ggcttcaaag gatatttcgt
     9481 aaattcgttc ttgaaaccct atagttttat gtttccgatg aaactgattg aagaatttac
     9541 aaacttatta acacttgctt tacgtcttta tgggaatatt tatgcggggg aagttttgct
     9601 aaccttgatt gcaaaaatga tgacaagctt aggctggttc tcattaccat tagcaattcc
     9661 attagagatg gtctggatcg cgttctcctt gtttattggg agcatccaag catttgtctt
     9721 tgtcactttg tcaatggttt atatgagcca taagattgaa gtagaagaat aatactcggt
     9781 taaaaaacaa actactattt atctatttta ggaggaaaac aattatgaat tatatcgcag
     9841 cagcaatcgc aatcatggga gcagcaatcg gagccggtta tggtaacggt caagttatct
     9901 ctaaaacaat cgaatcaatg gctcgccaac ctgaaatgtc tggtcaattc cgtacaacaa
     9961 tgtttatcgg ggtagctcta gttgaagctg ttcctatctt aggggtagtt atcgccttga
    10021 ttctagtttt tgccgtttaa ttgaatcagt attaaggcag aaacaacatc gtttgttact
    10081 gcttttttac atggaaacta gaaatactcc aaagaaagga aggctcgcct atgctgaatc
    10141 aattggcaat tgcagaagtt ggcaatgcga tgttaggtaa tatcatcgtt gtcagcggct
    10201 catttttgat actactggct ctcttgaagc actttgcttg gggaccaatc agcgatattt
    10261 tgaaaaaacg tgaagacaag atcgccaatg atttagattc tgcagaacaa tctcgcatca
    10321 actcagcgaa aatggaacaa gaacgcgaac aacaattgtt agcctctcgt tctgatgcag
    10381 ctgatatcat caaaaatgcg aaagaaagtg gagaattaag ccgccaaaat attttgaagg
    10441 atgctcaaga agaagcagct cgtctaaaaa gcaaagccca agctgatatc actgtagaac
    10501 gtgattcagc gctgaactct gtaaaagacg acgttgcaga actctctctt caaatcgcgg
    10561 aaaaaatctt gaacaaagaa ttatctccag aaatgcatga atcattaatc aatcaataca
    10621 ttgaaggtct aggttcttca aatgaaacta gataaatata cagtaggaag acgttacggg
    10681 aaagctttat ttgaactggc gatcgattca aatcaagcag aagaaatcta tcaagatctc
    10741 gtaagtttac gtcaaatcta tgaacaagta cctggattag ggaatatgtt aagtgatgtt
    10801 cgtctagaac ctcatgaaaa acgagaaatc atggacaagc ttgtcagcgg ttatgatgga
    10861 atcgttaaaa actttttaga agttgtttat gagtataacc gaatggatga ccttttgttc
    10921 atgattgaag aatatgaacg tcgatatgat gaacatcaag ggttactatt gggaagtgtc
    10981 acaacagcag tcccactttc agacgaacaa cgaatacaat tagaaaagaa tgttgcaaaa
    11041 acaatggact atcaatcagt tgaattaaaa caaatcgttg attcttctat tattggtggc
    11101 gcgattgttg aagccaacca tcgagtaatc gacggaagca ttcgcacgca attagaaaaa
    11161 atgcgtaatc aattaaacag atagtacaaa gaggtaggtg aatcgaatgg ccatcaaagc
    11221 agaagaaatt agtgccttga ttaaagaaca aattgaaaat tatcaaaacg tgctttcagt
    11281 cgaagaaatc ggtaccgtaa cttatgtagg tgacgggatc gctcgtgcac atggtttaga
    11341 aaacgcgatg agtggtgagt tgcttgaatt ttcaaacggc tcatacggaa tggcgcaaaa
    11401 cttagagtca aatgatgtag gtatcattat ccttggcgat ttcgagtcca ttcgtgaagg
    11461 agataaagta aaacgaacag gtaagatcat ggaagttcca gttggagagg ccttgatcgg
    11521 tcgggtagtc aatccgctag gtcaaccaat cgacggacta ggtgaaatcg ttactgacaa
    11581 agctcgtcca gtagaagcga tggcaccagg tgttatgcaa cgtaaatctg ttaacgaacc
    11641 aatgcaaaca gggctaaaag cgatcgacgc ccttgtgcca atcggacgcg gacaacgtga
    11701 attagtcatc ggtgaccgta aaacagggaa aacttctatt gcgattgata cgatcatcaa
    11761 ccaaaaaggt caagatatga tctgtatcta tgtagcaatc ggacaaaaag attctacagt
    11821 tcgtacacaa gttgaaacat tgaaaaaata tggcgcaatg gattacacaa tcgttgtgaa
    11881 tgccggtgcg tctcaaccag caccattact ttatatcgca ccatatgctg gtactgcaat
    11941 gggtgaagaa ttcatgtaca acggtaaaca tgtattgatc atttttgatg atctttcaaa
    12001 acaagctgtt gcttatcgtg aactttcctt gctacttcgc cgtccaccag gtcgtgaagc
    12061 ttatcctggg gatgttttct acttgcactc acgtttatta gaacgtgcag caaaattaag
    12121 tgatgatcta ggcggcggtt caatgactgc tttgccattt gttgaaacac aagctggaga
    12181 tatctctgct tatatcccaa caaacgttat ctcaatcact gacggacaaa tcttcttaga
    12241 aagcgacttg ttctacgcgg gtactcgtcc agcggttgat gccggactat ctgtctctcg
    12301 tgtagggggt tctgcgcaaa tcaaagcaat gaaaaaagtt gctgggactt tacgtctaga
    12361 cttagcaagt tatcgtgaat tagaagcatt tacacaattc ggttctgatt tggatgcggc
    12421 aacacaagca aaactaaatc gtggacgccg tacagtagaa atcttgaaac aaaaactgca
    12481 tgcaccgcta gctgttgaga aacaagtagt gattttgtat gccttgacac atggattctt
    12541 ggacagtatc cctgtagaca gtattttaga cttcgaacat gaattattcg aatatctgga
    12601 taccaatcat tcagatattt ttgaaacaat ccgtacaaca aaagatcttc cagaagaaga
    12661 aacgttgaac agtgcgattc aggaatataa agacatgttc ttagctacaa aaggaaataa
    12721 ttcctctaca gaagataaat tgaaatccat tcaaaatgca tagtgaggtg agatgaatgg
    12781 gtgcttcatt aaatgaaatc aagacacgta tcgcttcaac gaaaaaaacg agccaaatca
    12841 cgcgggcaat gcagatggtg tctgcttcta agttgacaaa atctgaagct tcttcacaga
    12901 agtttcaggt ttatgcaaca aaagtaagag aaatcgttac gcatttgact gctactcagt
    12961 taaatgatat tgcctcagaa aatcctagag gggatatcaa ttacaacagc atgctgctca
    13021 gccgtcctgt gaagaaaacc ggttatatcg tcatcactgc agatggcggt ctggtcggtg
    13081 gatataacag ttcgatattg aaacaaacga tgtctatttt agaagaagac caccaatcac
    13141 ccgatgatta cgtgatgatc gcaattggcg gaactggtgc agacttcttt aaagcacgcg
    13201 gtatcaacct agcatatgag ctgcgcaatt tatctgatca gccaagcttt gatgaagtcc
    13261 gcaaaatcgt aaatatggca acaactatgt accaaaacga agtattcgat gaattatacg
    13321 tatgttataa ccatcatatc aattcgctaa ctagtcagtt tcgtgtagaa aaaatgctgc
    13381 caatctcaga cttagatcca gaagaagcaa cgactttcga acaagaatat atttttgaac
    13441 cttcaaaaga agaaatcttg tctcagttat tgcctcagta tgctgaaagt ttgatctacg
    13501 gtgcgatcgt tgacgccaaa acagcagaac atgctgctgg tatgacagca atgaaaacag
    13561 caactgataa tgctgctaat atcattgatg agctgacggt ttcttataac cgtgcaagac
    13621 aaggggctat tacccaagaa attaccgaaa ttgttgccgg agcttcggca ctagaatagt
    13681 attgagattg gaggaaaaaa gatgagttca ggcaagattg ttcaagtaat cggtcccgtt
    13741 gtcgacgtgg aattttcttt agaccaatcc ttaccagata tcaacaacgc attagttgtt
    13801 tataaaaatg acgaaaataa atcaaaagtt gttcttgaag cagcgttaga attaggggac
    13861 ggagtgatcc ggaccattgc gatggaatca acagatggtt tacaaagagg aatggaagtc
    13921 attgatacag gcaaagcaat ctctgttcct gtaggtaaag aaacattagg tcgcgtattc
    13981 aacgtactag gagatacgat cgatttagaa acacctttcc cagaagatgc ggaaagaagc
    14041 gaaattcata aaaaagcacc agcctttgac gaattaagta caagtacaga aattttggaa
    14101 acagggatca aagttatcga tttgcttgcc ccatatttaa aaggtgggaa agtcggacta
    14161 ttcggtggtg ccggtgttgg taaaaccgta ctgatccaag aactgatcca taatatcgcc
    14221 caagaacatg gtggtatttc tgtatttacc ggtgtaggtg aacgtactcg tgaaggtaat
    14281 gacttgtatt atgaaatgaa agattcagga gttatcgaaa aaacagccat ggtgttcgga
    14341 caaatgaacg aaccaccagg tgcacgtatg cgtgttgctt tgactggttt gacgattgcg
    14401 gaatatttcc gtgatgtaga aggtcaagat gtactgttgt ttatcgacaa cattttccgt
    14461 ttcactcaag ctggatctga agtatcagcc ttgttaggac ggatgccttc tgcggttggt
    14521 tatcaaccaa cattggcaac agaaatgggt caattgcaag aacgtatcac atctacgaaa
    14581 aaaggttcga tcacatcgat ccaagcaatc tatgtgccag ccgatgacta cactgacccg
    14641 gcgccggcaa cagcattcgc ccatttggat gcgacaacca acttggaacg taaattaaca
    14701 gaacaaggga tttatccagc ggtagatcca ttggcttctt cttcaagtgc tttagcacct
    14761 gaaatcgtgg gagaagaaca ttataaagta gcaacagaag tccaacacgt attgcaacga
    14821 tatcgtgaat tacaagatat cattgctatc ttaggtatgg atgaattatc cgatcaagaa
    14881 aaagtgttag tttctcgtgc ccgcagagtc caattcttct tgtcacaaaa ctttaacgtg
    14941 gctgaacaat ttactggtct tccaggttca tatgtccctg tagaagaaac agtgaaagga
    15001 ttccgcgaaa tcttggaagg caaatacgat gatcttcctg aagaagcttt ccgaagtgtt
    15061 ggccgaatcg aagacgtcgt agaaaaagcg aaaacactag gctactagaa aggggtgccc
    15121 catggatcaa tatttaacag taaatgtggt aactcctgcc ggtttggtct atgatcacca
    15181 tgcagctatc gtcgttgcac gtacgacagc tggtgagctt gggattttgc ctaaacatgc
    15241 accaatcatc gttccattga cgattgatga agttcgtgta aaacgaacag attcagatac
    15301 ccacgtcgat tggatcgctg ttaatggcgg aatcatggaa gttcgtgata atgttgtttc
    15361 aatcgttgct gatagtgcgg aacgtgaacg tgatatcgat gtatctcgtg cggaacgtgc
    15421 aaaacaacgc gcagaacgcc aaatcgaaga agcaaaagca aaacaagata cgaacgaatt
    15481 gaaacgggca actgttgcgt tgcaccgagc aatcaatcgt atcaaagtat ctaagcactc
    15541 ataaaatgag atgcggatgt ttatccgtgt ttaagaacag taaaaagagg ttatgacaga
    15601 agtggtcagc ttcaagacat aagaaggaat ttacgaaaat tgcttctcaa atttttgtga
    15661 aatctcagct tatttttcga agaagctact tctggaacac cgtatatcag aggttgtgaa
    15721 atcagcgttt tgtcctgagt attagagaaa caaatggaaa atagttcctc atattttgcc
    15781 gttttttgag ctaataccga gggtcagatg attgaacacc gtttatttgg aataagggac
    15841 tgcgacaaga cttttgtctc agtccctttt tttgcatatt tttagcattt atttcctaaa
    15901 aaatgtaagg ggattcctat atttttaagt atacttgttt ttccttttat acattttatg
    15961 gtattatcat tttattagtt attataaaac aatcgttaga aaggacgtca ttatgcaagt
    16021 atacggaatt gatgcggtgc ttcgaatcgt gagtcatttg gcgtttatct acttagcctt
    16081 ctggtcttta cgttcgttac gcattgaaac ttttttcaga ccaatgcata atacgcaaat
    16141 tagaatggca atcgtacttt tttcaatttt tttagggtac actgcaagta attttttctt
    16201 agaagttatc gctttatgcc gaaatctttt cgttagcctg taaattttaa aaaaaggtac
    16261 tattttaaaa gcaaggatgt tataatagaa aagattttga gtaagtgtat gctcattgga
    16321 attttttgga gggaacaaca tggaagagat catcgtaaga ggtggcaatc aattaaatgg
    16381 aacagtaaga attgaaggag ctaaaaatgc tgttttgcct attttagctg ctagtttgtt
    16441 agcagaagaa ggtattacga cattagacaa cgttccgatt ctttctgatg tcttcactat
    16501 gaatcaagtg attcgtcact taaacgtaga tgtagatttt gatgaacaaa agaatcaagt
    16561 aacaatcgac gcttcaagac aattagaaat cgaagcgcct tatgagtatg ttagtcaaat
    16621 gcgtgcttca atcgttgtga tgggtccgct acttgccaga aatggacatg caaaagtagc
    16681 tatgcctggt ggatgtgcga ttggtaaacg accaatcgat ttgcatttaa aaggatttca
    16741 agctttagga gcaaaaatta ttcaaaaaaa cggctatatc gaagcaattg cggatgaatt
    16801 gatcggtaac acgatttatt tagatttccc tagtgtgggt gctactcaaa atatcatgat
    16861 ggctgccgta aaagcaaaag gaacaaccat cattgaaaac gtagctcgcg aaccagaaat
    16921 cgttgattta gcaaacattt tgaataaaat gggcgctcaa gtctatggag ctggtactga
    16981 aacaatgcgt attgaaggcg tggatcattt acatgcagtc aaccactcaa tcgtacaaga
    17041 tcgtatcgaa gcaggtacct ttatggttgc tgctgcaatg acacaaggca atgtgctgat
    17101 tgcagatgct atctctgaac ataactgccc attgatttct aaattgatcg aaatgggtgc
    17161 agaaatcatt gaagaagaag gcggagtccg tgtcatcgga ccaaaacata tcttacctac
    17221 agatgtaaaa acgatgcctc atcctggttt ccctacagat atgcaagctc aaatgacagc
    17281 tatccaatta gttgcagaag gtacaagtgt ggtgactgaa acagtgtttg aaaatcgttt
    17341 ccaacattta gaagagatgc gccgtatgaa cgctcatgtc aaaatcgacg gaaatgtagc
    17401 aatcatggat ggaaaccatg aattgcaagg tgcagaagta tatgcaacag acttgcgggc
    17461 agcagcagca ttagttttag ctggcttgaa agcaaatgga atcacacgtg tgcgtaactt
    17521 gaattatcta gaccgtggat attataattt ccatatcaaa ctacagcaat taggtgcaga
    17581 cgtcgaacgt gtagacatgg atcaaacttc tgctgaaaaa acagcacaaa cgattgctta
    17641 aggaagtggc tgaatgagta accaacgata tatcttatta actttgataa agattttagt
    17701 ggtgatctta ttgcttatcc ttctttttgt ggccggaacg atgatcggat atggtgtcat
    17761 cggtggcggc aatccattta aagtattcca gccaagtttg tggattcata ttcgagactt
    17821 ttttcattga taaataagaa tcacagtggt tctagtcgat atgaagtgag ccatgaagca
    17881 gaacatgata aaagaaaaca gaagggaacg ttgacgttag tcgcgatccc tttttttagt
    17941 aaaagaaaag aaggaatcta attgatgaag aagatattga tttatttagt tagaggatat
    18001 cagcgcttta tttcgcctgc atttccacct agctgccgtt attacccaac ctgttccaat
    18061 tatatgataa aagcaattca aacccatggt gcgctaaaag ggacggtaat ggggactgca
    18121 cggatcttac gctgtcatcc ttttgtcaaa ggcggtatcg attatgtacc attgacattc
    18181 cgattaacgc gaaataagaa agataaaaaa gaaccagatt ataaaaaggt tgtgaaaaat
    18241 acgggtagca ctgagcgata aagaaaaaga ggaaatttat tgtcaaagta acaactccgc
    18301 aactacttat atgggggaca aaaaatgatc gaagaactaa acaagaaaga tttaccatgg
    18361 tccttgttat tagatgcaga tcctgataaa gaaaaagttc aagtatatgt ttccagaggg
    18421 agtggctgga tatggaaaga aaaagaaaaa acaataggtg tactgatcta tgtggcaagg
    18481 gaaaaagaat acgaaatcgt caatgtagca gtaaccccaa cgtatcaagg aaaggggatt
    18541 ggcggaaaat tacttgagac agcttttcag aagctttcac agctagcttc aaaccaaact
    18601 cggatcatta tacgtactgg cactactagt agcgctgcgt tacacctcta tcaaaaaatg
    18661 ggctatgtgg agattggtcg agtcaaagac tattttatcc atcattaatc tgagcccatt
    18721 tttgaaaatg gagatcaatt aagggatcaa gtgattttag caattcactt acctaaaaat
    18781 agctttaact aataaacttt caattcgaga aaatgctttc aaatgctaaa tagatacatt
    18841 acaatagctt tagcaaacaa aaaggagaat atttttatgg gaatattagt ttttgatttt
    18901 ggtggatcgg ctgtcaaata tggttgttgg gatggcaaag agattaaagg taagggacaa
    18961 tttgcaacgc ctgaatcttg ggaagaaatg aaaacgcaat tatttcaagt ttataaaaaa
    19021 atactcgttt cttttgaagt cgaaggaatt ggaatcagct ctcctggagt agtgaataat
    19081 gagaaacagg tgattgaggg aatcagtgcg attccttata ttcatggatt taatattttc
    19141 cgagatttgg aaactctgtt tcaactccca gtaacgattg aaaatgacgc caactgtgcc
    19201 ggaatggctg aattttatga aggtgctgcc cgtgattatc aagatgttgc ttttgttgtg
    19261 gcaggaactg ggattggcgg ggcgttgttc acgaaaggac aaataaataa aggggcacat
    19321 ctttacggtg gagaatttgg gttgatgttc ttagatggcg ataagacatt cagtaaactt
    19381 ggtacagcgg tacagatggc ttggcgttat tgtgaacgca aaggtctcga taaaaatgct
    19441 tataccggaa aagatgtctt tgaattagca gaaactggag atgcaatagc aaaagaagaa
    19501 gttgagagtt tttatacgta tcttacaaag ggattattca gtattcaatt ttcgtttgat
    19561 ccagaagtga tcgtattagg cggcggggtt tctgcaaaag aagggctcat tgatgagatc
    19621 aaaagccgaa tgaagaagct gacagaacaa ttcgatctgc atgatttcga accgcagatt
    19681 ttattatgtg agtacagaaa cgatgctaat cttgtaggtg cagcagcaaa ctatctcgct
    19741 gtacgtcaag gagagaatta agagctttag agaaggtgca gcttgcataa aagaagagaa
    19801 tgaaatgaat aggagatttt tacctaagga atgttttatt tgctgcagta tgataaaata
    19861 tctgagaggt gaaaatgatg tcaaaaaaaa ataaagatat tgaagtgcgt atagaagaag
    19921 tgaaaaaaga tatcaaaggt aagaattatg aagtcactca gttatttata gggaaaaaaa
    19981 tgattggtga gatcttagcc tatgggccaa aagaatatga aattttcttt ggtgaagaag
    20041 attttggaaa agaaaaaagt cttgaaaatg cgatagaaac agtgattcga cactggaatc
    20101 tgcacgaata aaaaaatatc aaaaaaactt tcaataaagg gttgcaaaaa tctggaaaat
    20161 taggtattat aactaagtca ggttgataca aacctttcgg aggagtagcg aagtggctaa
    20221 acgcgacgga ctgtaaatcc gttccttagg gttcagtggt tcgaatccac tctcctccat
    20281 ttcattgggg tatagccaag cggtaaggca agggactttg actccctcat gcgttggttc
    20341 gaatccagct accccagtat
//
LOCUS       DBBGRF010000053        19505 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000053 DBBGRF010000000
VERSION     DBBGRF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.053"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(461..1090)
                     /gene="udk"
                     /locus_tag="ACIZD4_002231"
     CDS             complement(461..1090)
                     /gene="udk"
                     /locus_tag="ACIZD4_002231"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGC5991119.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1174..1869)
                     /locus_tag="ACIZD4_002232"
     CDS             complement(1174..1869)
                     /locus_tag="ACIZD4_002232"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGC5991120.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1882..2598)
                     /locus_tag="ACIZD4_002233"
     CDS             complement(1882..2598)
                     /locus_tag="ACIZD4_002233"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGC5991121.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2928..3533
                     /locus_tag="ACIZD4_002234"
     CDS             2928..3533
                     /locus_tag="ACIZD4_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HGC5991122.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3858..4181
                     /locus_tag="ACIZD4_002235"
     CDS             3858..4181
                     /locus_tag="ACIZD4_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGC5991123.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4363..5733
                     /locus_tag="ACIZD4_002236"
     CDS             4363..5733
                     /locus_tag="ACIZD4_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGC5991124.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5863..7164)
                     /locus_tag="ACIZD4_002237"
     CDS             complement(5863..7164)
                     /locus_tag="ACIZD4_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGC5991125.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7394..9385)
                     /locus_tag="ACIZD4_002238"
     CDS             complement(7394..9385)
                     /locus_tag="ACIZD4_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HGC5991126.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9529..9795)
                     /locus_tag="ACIZD4_002239"
     CDS             complement(9529..9795)
                     /locus_tag="ACIZD4_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC5991127.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="ACIZD4_002240"
     CDS             complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="ACIZD4_002240"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGC5991128.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="ACIZD4_002241"
     CDS             complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="ACIZD4_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGC5991129.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13139..13702
                     /gene="def"
                     /locus_tag="ACIZD4_002242"
     CDS             13139..13702
                     /gene="def"
                     /locus_tag="ACIZD4_002242"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGC5991130.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13955..14476)
                     /locus_tag="ACIZD4_002243"
     CDS             complement(13955..14476)
                     /locus_tag="ACIZD4_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGC5991131.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14479..15321)
                     /locus_tag="ACIZD4_002244"
     CDS             complement(14479..15321)
                     /locus_tag="ACIZD4_002244"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGC5991132.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15314..16039)
                     /locus_tag="ACIZD4_002245"
     CDS             complement(15314..16039)
                     /locus_tag="ACIZD4_002245"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HGC5991133.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16215..16511
                     /locus_tag="ACIZD4_002246"
     CDS             16215..16511
                     /locus_tag="ACIZD4_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991134.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      16767..16941
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            17079..18671
                     /locus_tag="ACIZD4_002247"
     CDS             17079..18671
                     /locus_tag="ACIZD4_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGC5991135.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18684..19424
                     /locus_tag="ACIZD4_002248"
     CDS             18684..19424
                     /locus_tag="ACIZD4_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC5991136.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5579 a         4002 c         3701 g         6223 t
ORIGIN      
        1 agggggtgcg acaaaagagc ttcttcaaaa aaataagtcg aaatctcaca caaattcgag
       61 aaataatttt cgtaagtttc ttcttattta ttgcatctga ccacttctgt tacaacctct
      121 cgttaaacgg tgttcaaaag cttgcatcta cgataataag cccaacccaa cgaaaaacgt
      181 gaggagctgt tttatttgga tgctcttatc gcttgatgca aagacagctt ttttacaacc
      241 tctacttcac ggtgctcaat cagctgacct tcggtattag ctcaaaaaac ggtaaaatat
      301 aaacagctat tttccgtttc ttctttttaa tacttaggtc aagatgctgt tttcacaacc
      361 tcttgttata aataaaaaaa acagttggct ggtgactgtt caaaaagcag aatccttgct
      421 tttcaaacgg tcgcagtccg ttcaactgtt tcgctgcgca ctatttatgg tttaagaaac
      481 tagctacttt tgttgtaatc aaatcaatag caacgtggtt ttctccgcct tctggaacaa
      541 tgatatccgc atagcgcttc gttggttcga taaattgatg atacatcggt ttaacaactg
      601 tcaaatattg ttcgatcacg gagtccaatg tgcgtccccg ttcttccata tcccgtttga
      661 tacgacgaat gatacgaatg tcatcatctg tatctacgta tactttgata tccatcaagt
      721 cacgcagacg ttcgtcttct aaaatcagga ttccttctag aatgatcact tcttttggtt
      781 cctgaatgat cgttgcctga cttcttgtat gcgctacata gtcatacacg ggtttttcaa
      841 tggctttata gttcagtaag tcgcctacat gctgaatcag cagatcatta tcaaaggcaa
      901 atgggtgatc gtaatttgtg ttcaatcgtt cttcaaaact caaatggctc tgatccttgt
      961 aataagaatc ttgttcaagc atcatgatgg aatggtccgg gaagttgttg aaaatcgcac
     1021 ggctgacact tgtctttccg cttccggatc cacccgtcac accaatgata attggcttgc
     1081 tttttgtcat tgactaaaac ctctttcgta tccgtttttt cattctaatc tattatagcg
     1141 aaaaaacacg aaaatgctat atttttctga aaattaatcc ttttcaattt ccaataatga
     1201 ataaagttcc tctaatgaat cgattcgata agtaggctgg atttcttcga tttctggtaa
     1261 tttatttcta ttgaaccaaa tcgtatcgat ccctgccata tttcctcctt tgatatcaga
     1321 agtcaaagaa tcaccaatga tcacagtttg ctttttatca aaattaggaa tgtgggaaaa
     1381 gacatgatca aaaaattctt tcatcggctt ttgcgctccg acagcttctg agacaaagat
     1441 atccttgaag taatcaagca ttcctgcatc tgttaatcgc cgatgttgcg tgtgcgacac
     1501 accgttcgtc acaatataaa gatcagcatg cggatggacc tttttcagga tttctagact
     1561 tcctggaaca agatcatgac cttggttcaa gtagtggcgg tagcgttttt ccatttgatc
     1621 actatctact gttttcccaa attgctggaa aagtaaccca aaacgactgc ctattatttc
     1681 ttctcgtgat agtctgcctt tttcaaactc ctgccataaa tgatgattca aagccttata
     1741 gctggtttcg atttctggtg tcaatgtgat tccttgttct gcaaacaaag cacttaaagc
     1801 attggcttca gttaattgaa aatctaacaa tgtatcatct acatcgaaca ataaagtttt
     1861 atatttcatc tttttgacct cctatttaaa ataaatactt aactttttca tctctgctaa
     1921 tgtcaacgat cgatactcgc ctactcctag ctgttcatct aattccaatg gtcccatgct
     1981 tagccgtttc aatgcggtca ctttctttcc ttgggctaag aacatctttt tgacttgatg
     2041 gaattttcct tcttggatcg tcaataaaac cgtactttgg tgcttgtctg ctttgagtat
     2101 ttttaaatca gccggcttac attgataccc atcagcgaat acgattccat tttcaaatgc
     2161 tgttacgtct gccggtgtca ccctttcgtt cacaactact tgataagtct ttgaaacctt
     2221 tttttctgga agtagcattt catatcccaa ttgtccattc gaagtgatca gcaatagtcc
     2281 tgttgtatct ctatctagtc ttcccactgg atataatggt tggaaacgat cggcacttgc
     2341 aatcagatcg attactgtcg tcttttctgg atctgataca gctgtaacag ctttttcagg
     2401 tttattgaga agataatagg actcatttgt ttctaagtgt tcacctgcta cttcgatttg
     2461 atgcagtaaa ctatctacat ttcgattttg tcgaaattcg actgtgccat ctatcatcac
     2521 ttgcttcaaa gcaaacagcc gcttcatttc cttgcgtgtc gtttctaatt tttcttctat
     2581 taatttatct aaacgcatgc tgtttccttt cttattacta ctaattaatt ataccttgaa
     2641 tattcttgct tgcaaataca tcatcatagt tattccttga cttaattaac agttcacgtt
     2701 acggttaaat agtaaagtga attggatttc tcatacacag cgtaatgacc tggtggagaa
     2761 aagttgaatc ctgactttct aaggggagat gcgcgcatct ctccttttgc gcttttttaa
     2821 gcgccctgcc ttcgatgatg tgcacgagat tagcctttag aattcactta aataaaatct
     2881 gtccgttacc aaagcagaca gtcacatttt aaggaggaat tttggttatg tcagtatcat
     2941 tagaagtaag taaaagagaa gtacgtcccc gttcattaag aaacaaactt cgtcacgaag
     3001 ggaaagttcc agctgttgtt tatgggtata aagtagaaag tacccctatc tcattcgatg
     3061 gtttgacact aagcaaattg ttgcgtgaac atggagcgaa cacagtcatc acgatggaca
     3121 tcgatggaca aaaagtcaat acattggttc acaagatcca aacgaacact tttaccaatc
     3181 atttcgaaca tgcagaattt ctatctgtaa acatgtcgga agaaacagaa gtcgaaacag
     3241 aagtcgttct tgttggcgaa tcagtgggtg ctaaatctgg tggagtgtta gctcaaaact
     3301 tgtatacagt agtcgtatct gctacaccag acaaattgcc tgaacgaatt gaagttgacg
     3361 tgacaaactt ggaattaggt gattctatta cagtagccga tcttccaaaa aacgacgatt
     3421 acaaattcgt gaccgacagt gaagagcaaa tcgctgctgt agtcgctcaa agtgaagaag
     3481 aaagcacagg tgaaggtggc gaaccagaag tgatcggttc aacagaagaa taatactgaa
     3541 acaatcaggt ggtgttagaa gcggcgggtc agcagctttt aacacgcctt ttttatttct
     3601 aatcgtttat tttcatatgg ggcttccact tttgtaaatg gctttacaaa cgaaaaatcc
     3661 taatttacca agcttttcct cgcatacttt tatcgtacct ttataaaaat ttatactttg
     3721 aaaaaaagta ttcaattatt gttgcatttt tcctgattct ttattagaat gaaccctcgt
     3781 tgaagtaagt atttctagtt tatcctagga ttaattataa aaataaaaca ttcgttgatt
     3841 cgaaggaggt taaacagatg tttgaaagtt ttgatagcag ccgcaaccgt tacgcttcag
     3901 ttggtgtcgt atcaagtttg ccagatgaat tgattgacag tatatggttt attattgacc
     3961 tagatcttaa gggagtcatt ccattagaaa atatattaac ctttgatttg atcgaaaatc
     4021 gtggaaaagt gacgatgcat ttttctcaag caggaagcaa tgtggaaatg gatattgatt
     4081 tgccgtttgc ctattcgaac caatttcctg ctcaagtata cgcctatgat gacggtacga
     4141 gagaaacgat ccttttacca agtgagatta gacaatatta aggtgataga taaacgtgga
     4201 tgtcccttat tttacagacc aggccaagtt gttgattctt tgactcaatt cttggcttct
     4261 ttttatggag tttcataaat tatcattgat ttctaattgg tattctcagg ataaacgcta
     4321 tatactacta actaaatttt aaagatataa ggagtttaaa agatgcgcga tttaacaaaa
     4381 ggaagccccg ctaaactgat tttgatgttc actgttcctt tactgatcgg aaatgttttt
     4441 cagcagttct acaatatgat cgatatgatc atcgtgggtc agacgctagg taaaaatgcg
     4501 ctggcagcgg ttggtgcaac tggaagcctg acatttttga tcattggctt tgcccaaggt
     4561 ttaacagctg gtttagccat tattaccgca caacgttacg gtgcaaaaga ttatcggggt
     4621 ctgaagaaaa gttttgctgc tagtgttgtc attagtcttg tcgtcactgt gattttaact
     4681 gtcctaagtc tcctgtttat tcgtccgatg cttcaattga tgcaaactcc tcctgaaata
     4741 cttgatcaag cacaaacatt tatttcaatt attttattag ggatctttgc atcagtcagt
     4801 ttcaatttgc tttctaatgt cattcgcgca cttggtgaca gccgcacacc actattcttt
     4861 ctgatcattg cggtcatcat caacgtcgta cttgatttga tctttattat ctattttggc
     4921 atgggtgtgg aaggtgcagc tattgctaca gtaatcgcac aagtttcttc cagcgtactg
     4981 tgtctagtgt atatcaagaa aaaaatgcct ttgttacagt tacgcaaaaa agatttcaaa
     5041 tttgaaaaag aagagtttgc tgtacaccta aatgctgctt tgccaatggc gtttcaatct
     5101 tcgatcatcg ctgttggtgc tatcgtgtta caagcagcac taaatagtct agggacagat
     5161 gtcgtagctg ctcaagccgc tgctggtcgt atcgaccaat ttgcaaatca gccgatgatg
     5221 tcatttggta ttgcaatggc aactttcact gcacaaaact atggtgcgaa agaatatggc
     5281 cgaatcttgc aaggggtacg tcaaacttta ctgatgagtg tcggatttag tctcttagca
     5341 ggtgctatcg tcattttctt cggtcatttc tttgttcaat tgtttgttag cccatcagaa
     5401 acacgtgtat ttgaattagc acaaacctac ttcaatatca atgggtctct ttactggatc
     5461 ttagcagtcc tgttcatttt acgctacaca cttcaagggc ttggacaaag caagatccct
     5521 acgatcgccg gtatgatgga attgcttatg cgttcttttg cagctatcgt tcttacagga
     5581 atgtggggat acccaggagc agcagcagct tctcctttag cttggatcgg ttctgttgcc
     5641 gtgttgcttt actcttatat gcgttcgatg aaacaattga aacacatggg tgaagaggaa
     5701 catttcacat tagaacatgc agaagcaaga tagccttgat taaaagaaat cgttgcggct
     5761 aaaaatgaaa acttttattg aaaatatctt cttcgtttac cgaaaacagg ttttttagat
     5821 aacaaaaagg ctgtgacaaa aaatgtcaca gccttttttc ttttattcta tttttctttc
     5881 cgtggactct actttgaaat aatcgatatg tgcatgctgg tattctaata ccgtgaaacg
     5941 gaatgatgca atctcaatga ttgttcctgc ttttatttct ttatatcggc tagaagcaaa
     6001 gcccgcaagt gtagtaaaat tcgtttcttc aaactctgga atctctacat gaaaataacg
     6061 ctggaaatca tctaatgtta gtttgccgga gatgatataa gagccatctg actgttccgc
     6121 tatcaatgct tcgtccaaat ctgtctcatc tcggatttcc ccgacgattt cttctaaaat
     6181 atcttcaatc gtcactaagc cgcttgtccc tccgtattca tcttttaaga tagcaatatg
     6241 ctttcccttt tttcgcatga tcgtcaataa tttttttata gggatcgttt cagttgttac
     6301 gatcggctct tcaatcaact gttctactgt cagctggtca tctttataag attgcttgat
     6361 caaatctggc aaggtgacat aacctaaaac attgtctttt gattctaaga taaccggata
     6421 gcgagtatgt ccttgttcaa tcgaagcttt tatcgcttct ttgacggttt ctgaagcttc
     6481 gaatacttgc atggacgtac ggtctacttg tatatctttt gccaaggtat catcaaattc
     6541 aaacacgttt tccaaataat gatattcttc tttggtcaac tctccttttt cataagaatt
     6601 caatgcgact aatgtcagct cttcttgaga caatgtctct tctccttcag atacgagacg
     6661 cacacctaat agcttcccta gccctgcagc tgaatgattc aatacccaaa taaaaggaaa
     6721 cattacttta taaaaataat gaagtggttt aactacgaac aagacgacct tctccgtatt
     6781 gacgatacta tagctcttag gaagcagttc gccaataacc acatcgatat acgtaactaa
     6841 aataaatccc agcgccacag agattgtact gctaatagcc gaactaaaag gtagtttacc
     6901 gatcactggt tctagtaaag ccgcgacaga tccttcaccg acccacccga tgatcaaacc
     6961 ggttagcgta attcctaatt gactagctga taaatagtta tctaaatggt gtgtaacatg
     7021 aagagctagc ttggcgttct ttacattttc cttttctagt tgttccaatc ttgatcgtct
     7081 gattttcact aaagcaaatt cacttgctac aaaaaatgaa gtaattgcaa tcatcaaaaa
     7141 taaaataatg aaattgataa ccatattctc ccgcctttct ctttttctat tgtacccttt
     7201 ttctacaaaa agattgaaaa taatgcgtat tcatatttag gaataaaaaa ggagatgcgg
     7261 catttttcag ccacatctcc ttatcacttc aaaatcattg cgttacttgt tgctaaacag
     7321 ctttttcatg acctctgata aacggtgttc aagtagctga cattcgacat tagttcaggt
     7381 caaagcgcta ctttcacaac cgctctttca accatgtttt ccgagtattt ccaatgataa
     7441 gcggaacagt ttcatgtttt acttcgctgt actctagccc aaaccatgtt tctggcgagg
     7501 tagcgatttt tttgattgcc agttttgcct gcatgatttg acgttgccat tttcctagag
     7561 ttgtcacatt ggaaactact tcatcaatca ggacaaattg gaaatcgcca acttctcgcc
     7621 ctggtgtcag agagtatctt tgtggctgtt ttggcaaacg gccttgtttc atcaaatcat
     7681 ggatgacttg gcgaacatat acgttgattt cctgttggac cctgaaacct aagaacagat
     7741 tcacttggac aataaaatca gtgtccatca tatctacttg atattctttc gtatatggct
     7801 catccgtcac ttccacatga acaaaccaat agactcgtgc tcttttaggc cgtttatcta
     7861 aaatcgaata gatgaactgt cggccaactt tatcttcagc catatcagga accaagaaga
     7921 ccacatttgt ctgatagatt ggtaaagaag tatcatcacg taattctcta agctgcggga
     7981 tataatctct caaagacaca tcctcggttg acgattcgcg aataatgttc ccttgttccc
     8041 aaataaacat cacgactaag atgatcaaac caatcagaac ggctacaaaa ccgcctcgga
     8101 agaatttgac aacacttgag ataaagaaaa cgacttctat cgcaccgaag aaaaaggtaa
     8161 ctaaatatgc aagccaacga gaatgcccat tttggataag ataaaagtaa agcagtgctg
     8221 ttgtcatcaa catcgtcaca gtgatcgata gaccgtaagc agcttccata tgatgagacg
     8281 ttcggaatgt gacaaccact agagaacagg cgatccataa aatcagattg actgctggga
     8341 tatacatttg cccgatactg ttcccaggat acatgatctt taaccgaggc agcagtttca
     8401 acttgattgc ttctgaaact agcgtaaacg aacctgtaat caatgcttgc gaagcaatga
     8461 ctgcagcgac tgttgcaaaa gcaacgccga tcacgatcca actttgaggc atcatttgga
     8521 agaatggatt caggttcttg atttgctgtg cttcagggtt ttgataaaca ttcaacaacc
     8581 acgcagcctg cccaaaataa ttgataacca aacaaatttt gacgtaaggc cagctcagac
     8641 gaatatttcg tttgccgaca tgtccaagat cggaataaag cgcctctgca cctgtcgtag
     8701 ccaggaaaat atttccaaga atgaacaagc ctaatttgtt atctgcacta aaaagcagct
     8761 ggatagcata ataaggattc agtgcacgga taactgtcca gtcttgactg aagttcatta
     8821 atcccattac gcctaaaaaa gtaaaccaag cgaacatgat tggtccgaat gcttttccga
     8881 caatatctgt accaaagcgt tggaccatga ataaaacaaa aataataact aaagtgataa
     8941 tgacgatcac gttctggtta ttaccgaacc ggtcaaaaaa ctgcggaatt cctcgcaagc
     9001 cttcaatcgc agtcgttacc gtcacagcag gggtcaatac cccatctgct agtaaggcag
     9061 ctcctccgat cattgcagga atgatcaaat atttcccacc ttttcggaca agtgtgtaga
     9121 gtgagaaaat tccaccttca ccatggttat ctgcattcaa tgcaatcacg acatatttga
     9181 ttgttgtcag tagagtcaat gtccaaaaaa tcaatgagac tgatccgata acaaaatcag
     9241 gattgattcc tgacaatccg ccattatctt caacaatcga tttcataacg taaagcggac
     9301 ttgtcccgat gtctccgtag acgactccca tcgctacaag caggccagcc attgatatct
     9361 ttttggtatt gtgcgttgtt gccacgtttt tccctcattt cttgttatat ggatatcctt
     9421 taggtaagct tgaatgatag atgatattct tatccatgac acccgctttc ctaaattgct
     9481 tctaattatc caagtaacac actgaagtgt caacttattt gaataaaatt attctttctt
     9541 tggacgttct ctgatacgtc ttgccacaaa tgaataaaga gcaaggcaaa aaattgcacc
     9601 caataatgct ggtatcaaat aaaaaccgcc gagttccggt cccagtggtc ctagtaaaaa
     9661 ttcgccgagc caactaccta aaaaaccgat aatgatattt ccagatacgc ctcccgggac
     9721 ttcctttcct aaaattgcgc cagctatcaa acctaatata ccgccgataa ataacgacca
     9781 taaaaaattc agcatctcct ttccctcctt tatccatatt tctcactttt attttacgct
     9841 ttattcagaa ggactccaaa aatatgcgcc aagaaactcc agaaaaaaag aagttgtaac
     9901 aaaagtgttc agcttatttc cgtagaagct gcttctggaa caccgtgaat cagaggttgt
     9961 gaaatcagcg gtttgacctg agtattagag aaacaaacgg aaaaatagtt cctcatattt
    10021 tgccgttttt tgagctaata tcgagggaca gctgattgaa catcgtttat tggagaggtt
    10081 gtaaaaaagc tgttctgcat caagtaataa gaacagccaa gtaaaaacag ctcctaatgt
    10141 ttttaacttg gctggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattcgaaa
    10201 aaaaaggact gtgacacggc ttttgtcaca gtcccctttt ttcgaataat tattgtcccc
    10261 ctgtcacctt cacgatcaca agtacattat tcctatgaat taaattattt ttcttcattt
    10321 ttcgttgaac catcttcgtt caacattgct tttcttgaca gatttacgcg tccttgttta
    10381 tcgatttcag ttactttcac aaggatctca tcacctagtt taacaacatc ttcgacttta
    10441 ttgacacgat cgtttgctaa ttgggaaata tggacaagtc catcttttcc tttgatcaag
    10501 ttgacgaatg caccgaattt ttcgatacgg acaactttcc ctagataaac ttcaccaact
    10561 ttgacttctt tggtcaaatc ttcgatgatc ttgatagctt ttttgatcat ttctgcatca
    10621 gctgaagcaa tacttacttt tccatcttga tcgatatcga ttttcacacc agtttcatcg
    10681 atgattccgt tgatcgtatc gccgccttta ccgataacat ctttgatttt agcaggttcg
    10741 atctggatca tttcgatttt tggtgcatat tggcttaatt cttcacgtgg agcagcaatc
    10801 gttgaagtca attcttctaa gatttccata cgtgcttgtt ttgcttgagt taatgcttca
    10861 gttaggattt gttctgtgat tccttgaatc ttgatatcca tctgtaaagc agtgatacca
    10921 tcttttgtac cggcaacttt aaagtccata tcgccaagat gatcttccag cccttggata
    10981 tcagttagga tcgtatagtt ttcaccatca gaaacaagtc ccatcgcaat accggcgact
    11041 ggcgctttga ttggtacacc tgcatccatc aatgctaatg tgccagcaca gatacttgct
    11101 tgggaagaag aaccatttga ttccaatact tctgctacta aacggatcgt ataaggaaat
    11161 tcttcttctg aagggattac ttgtgctaac gcacgttcac ctaatgcgcc atgtccgatt
    11221 tcccgacgcc ctggagagcc tgcacgtcct gtagaaccaa cagaaaattg agggaaattg
    11281 tagtggtgga tgaatcgttt gctgacttcc acccctaaac catcaatgat ttggtgctct
    11341 cctagaggtg cgagtgtaca agctgataaa gcttgtgttt gtcctcgtgt gaacaaacct
    11401 gatccatgta cacgtggcaa taagctgacc tctgatgaca atggacggat ttcatccaat
    11461 ttacgcccgt caggacggat cttatcgatg gtgatcaatt cacgtacgac atctttttca
    11521 agatcttctg tgatttgttt aacttctttc aacaagtgat cttcatcttc atgacctgca
    11581 aatttctcag cataagcttc gcggatatcg atcttcacct gctcgatatt atcttcgcga
    11641 gcaagttttt cttcagtcat tactgctgct ttcattgtag cgtaagaagc atcaaagatt
    11701 tcttttttca atacttcatc aacttgcagt aaagtcactt ccattttttc tttccctact
    11761 gcttgaacga tttcttcttg gaaagcaact aactctttga tagcgtcaaa accaaacagc
    11821 aatgcaccaa gcatgtcttc ttctgaaact tctttcgcgc cgctttcaac catattgatg
    11881 gcttgtttcg ttccggcaac agtcaattcg atatctgttt gttctgcttg ttctactgtt
    11941 ggattcaaga cgtactcgcc atttacacga ccaacttcta cgcctgcgat tgggccgtca
    12001 aatgggatat ctgagattga tagtgctaaa gaagaaccta gcattgctgc catagctggc
    12061 gagcagtctg tttctacact catcacgatg ttcgttactt ggacttcatt acggaagcct
    12121 tctgcaaaca tcgggcgaat tggacggtcg atcaaacggg cagtcaatgt tgcttccgta
    12181 cttggacggc cttctcgttt gatgaaacct ccagggattt tccctgctgc atacattttt
    12241 tcttcataat tgatcgttaa tgggaaaaag tctgtatctt ttgcttcttt agaggccaca
    12301 gctgcactta agactactgt atctccataa cggactaaaa cggctccgtt tgcttgtttt
    12361 gctagctgac cgacttcgat ttgtaaggga cggccgcccc atgtcgtttt gaatacttgt
    12421 ttttctgaca taacttctcc ttttccttct cgtgaaagca agacgctact aaacaaatga
    12481 aaactgccga aagccgtctt ttgagcagct ttcatttggt tagtaggagt ccatctagct
    12541 tgatcacgga attttactta attgatatac gagtaaaaaa agtgagattc atgtgaatcc
    12601 cactcttttt gactaaaatt aacgacgcaa gcctaaacgt ttgatcaatt cgcggtaacg
    12661 ttgaacgtca gttttacgta agtaagctaa caagttacgg cggtgaccaa cttttttcat
    12721 taggccgcgg tatgaatgat ggtctttttt gtgcacgcgt gcatgttcat tcaagtggtt
    12781 gatttcttca gttaatacag cgatttgtac ttctggagaa ccagtatccc cttcatggcg
    12841 agcgtattcg ttgatgattt cattcttgcg ttcttttgaa attgccattt ctttcacctc
    12901 tttcgattat tcccctgcga ctgagtaaaa cgttggtgat tcgcttaacc aagtggcagg
    12961 tcatgtgcct agagcacaca gctatacttt acctgaaacc gggttgaaaa tcaagtagtt
    13021 aatcattaag aaaaggtagt tttcaaacaa tcttactact acttttccat ttttgtggta
    13081 aactataatg cgaaaataga cttgaaacac agtcttttaa gaaaggggta catattccat
    13141 gattacaatg gatgatatca ttcgtgaagg aaatccgacc ttacgcgaag ttgcaaaaga
    13201 agtttctctt ccattaagcg aagaagatat ctctttagga aaagagatgc ttgagttctt
    13261 aaaaaacagc caagatccaa tcaaagctga agaactacac ttacgaggcg gtgttggctt
    13321 agctgctcct caattagata tttctaaaag aatcattgct gttcacgtac caagtcctga
    13381 cccagaggca gatggacctt ctctaagtac tgttatgtat aatcctaaaa ttttgagcca
    13441 ttctgttcaa gatgcttgtt taggggaagg tgaaggctgt ttatctgttg atcgagaagt
    13501 accaggatat gttgttcgcc atgccaaaat cactgtgtct tattatgata tgaatggtga
    13561 aaaacacaag attcgtttga agaattatga atcgatcgtc gttcaacatg aaatcgacca
    13621 tatcaacggt gtgatgttct atgaccacat caacgatcaa aatccatttg cactaaaaga
    13681 aggcgtattg gtgatcgagt agagaattgg caggttcctt cgatactatg ctacaagaaa
    13741 gctttataaa aaaggggagt gctcaaaagc tgcacttccc ttttttatgt ttctccacta
    13801 atcgaaattt agatagacat ctagaaatcg caattccaaa aaattctgtg tattggatac
    13861 gcatcttttc ttattttttc ttatttcttc catatgggtg tttatctcag agatgataga
    13921 atagtttcta ggataaaaag tagcagctac gatgttatcc ttcgtagagg attcctgctt
    13981 cagctagttt ttgtttgatg tttttcagca tatgcttttc tgggtagcgg atcgtatgca
    14041 gatggatgcc gcctgttaat tcggataaca aagtagcatt acttttttga taacgtctca
    14101 taaaggaatc gatatcttgt ggcgttttga tgtgcaaagt tcctgctaac tcaccgtaaa
    14161 ggggatgttc cacaattaca tcaatgattt caccaccatt ttcaacgatt agtctcagtt
    14221 cttcttctgt ttgatctttt ccatgctgga cagcgatttt actgatgtgc ccagtattgg
    14281 tttcttctgt ttcgaggata taacctcttg ctgttgccac gatactttta cctgcagctc
    14341 gtagtaaagc aatatcgcct acaatgatct gacggctgac tccaaaagtt ttcgcaaact
    14401 tgctagcact cactggtttt tctgtatttg ccaaggtttg catgatttgt tttcgccgtg
    14461 tctctccttc gatcacactt attcctcctt cattttgttt tggtattcgc gcgagtgttt
    14521 catcaaatca acatacgtgt ctgttattgt ttccttatat cccttatttt tcagcagact
    14581 aacaacttta tccaatactt gctgctctct ttttgcatca taaactgctt ggttttcttc
    14641 ttttttcact tgtcctattt tagttaccgt atccattctt ttttctaata aagcaaccaa
    14701 ctctcgatcg atcatatcga tcttatgacg taatgtttca agagactctt ctgttagttc
    14761 ttcctctact gtcttgatga tacgagcagg atttcctgca atcactacat tgtcgggaaa
    14821 agatttggtc acaaccgaac ctgcgccgac tactacgttg tcccctagag tgacacccgg
    14881 cgtgacgata actcctccgc ctaaccaaac attattaccg attttaatgg gttttgcgta
    14941 ctccagaccg ctgttacgtt tcactggatg tagtggatgc gtcgccgtgt aaagctggac
    15001 attcggagcg aacatgcagt tatcaccgat ttcaatcgtg ctgacatcta aaaatgtaca
    15061 attgaaattt gcataaaaat tctccccaac aaatatatta tatccgtaat caaaattgat
    15121 aactggctcc atatagattt ttttccctgt acggccaaaa gtctctttca acaattggga
    15181 tcgcagttcc gctgattctg cttggttgat gatttggctt tgacttcttg caaacatacg
    15241 gtcggcaacc agctcaggat cattggcaaa ataaagctcg cctgcaatca ttttttcttt
    15301 ttcggttttg aattcagtca taatctgctc ctaattcttg tatttttttg aaaacaaccg
    15361 ctccgtcttc ttgaataaac gtataaggct ccgctaaata aacaggcgtt tgattgatta
    15421 ctaagatttt ggctgacggc tggcgaaact gtaccagatc acaaaacgga tgaacttgaa
    15481 aactcgttcc aacaatgacg atcagctctg cttggctgac ggcataagcc gcctgctcca
    15541 tgactccatc ttgaaaccct tcaccatata acacgatgtc tgggcgtatt tgtcctccgc
    15601 atgcttgatg tttgtcgctg tgaagatatt ctttccagtc taccgtttgt tgacattttc
    15661 gacaatgaca ttgatacaga ctcccatgaa aattgacgag ttgcgggctt ttagcctttg
    15721 cgtgcaaacc gtcgatgttt tgggaaacaa cccaaacatt tttttctttc gctagatgtg
    15781 ctatttccaa atgaatgata ttgggttttg cttcaggatg ataaatcttt ttgacaaatt
    15841 gatagaattt atccggttca ttcaccattg cttgatgact cagcaagtat tccggctgct
    15901 ccatcccgtg gtagattcct gacaaagatc gatagtctgg cactccagaa ggtgtggata
    15961 cccctgcacc ggtcaaaaat gtaatttgct gataagctaa tatctctttt gctgcttcgt
    16021 ctactgttaa ttgtttcatg ttttgtcacc tcactttcca ttatagccca tactcgaaca
    16081 aatttattgt tgaaaagtca gaaaaatggg aataaaaaag tgttatgggc atttgagcaa
    16141 tttatcacaa tgttcactga caaaagaatg aaaacgtgtt acaatactgc tgtataaaag
    16201 tgaggtgaat cgatatgtta ccattcttta tttattgggg cgttattctg gcttgtatcg
    16261 cctggttagc gttaagcgtt tatttctctg ttttttatct tgtacgcaaa gaaaatggaa
    16321 atctttgggc ttttgcttta ttcaacgtga ttgccgcaat tgttttagcc attacattag
    16381 ccgtatatcg aacatggggc tggggaatca cccaatactc aagtttgatt tatctaatat
    16441 tagccattta tggcgtcgtt gttcttttgc aagcgatcct aggacgtgag ccaaagaaag
    16501 cggcagctta aatgatcgag atggaactgg acacaggaaa ttttctgttc tagttctttt
    16561 tttattgtat tacatacatt tttgtgtata attatactat cgtttgcaat ggatagatga
    16621 ttcacatttt gattgttttt tcggtaaaag taaagatttc tatatttatc agtatttttt
    16681 caaaaaccag cagttataga ttgacaaagc ctctcgagta tcgtaaactt tttttgtata
    16741 aataactgaa tacgagatgc ctcaatcaat gaggtagagg tcgcgagaat cattaaccct
    16801 gtggagtgaa gcaaacatgg agaagcagga atagggagga tcgccgaaat gtgcactttt
    16861 ttgcttggag tgtatgttgg gacgcaagtt aagagcttgc ggactgtctt agcagtgatg
    16921 ctaagttgcg ctatgttttg tgagaggttt atcaccttat ggaattttag cggccttttt
    16981 atatctataa atcggtcgct ttttattttt tcagataaag ctttaccgca tttcatctag
    17041 accgctcgtg tatcatataa tcagaaaggg agaaaaaaat gaaaaaaaat atggtttcag
    17101 ttgccgtact atttgctttt gtcttctcac tattcagtgt gggatctctg gcaaatgcag
    17161 atgaaaaaac accgagcgat gagtttcgcg taggtatgga ggctgggtat gcacccttca
    17221 actggtctca acaaacagat gagaataatg ccttgccaat tcaaggccaa aatagttacg
    17281 ccggcggtta tgatgttcaa atcgctaaaa aagtagcaga tggtttaggg aaaaaattag
    17341 tcatcgtcca aacgaaatgg gatggtctgg ctcctgccct tcaatcaggc aagatcgacg
    17401 cgatcatcgc cggaatgagc cctactgctg aacgacgaaa agaaattgat tttaccgatc
    17461 cttattacga atcacaatta gtagtagtag ttcaaaaaga tagcaaatat gcaaaagcaa
    17521 aaagtttagc agatctttct ggagcaaaga tcactgctca gttaaataca ttccactata
    17581 ctgtgatcga tcagatacca gatgtgcaga aacaacaagc aatggataat ttctcagcaa
    17641 tgagaacagc tttagcttct ggaatgatcg atggttatgt cagcgaacgt ccggaaggtg
    17701 taacggcaac tagtgtgaac aaagacttgg aaatgcttga attcagcggt gcagatggct
    17761 tccagacaaa cccggaagat gttcagattt ctgttggtat gcgtaaaggc gacccggata
    17821 tccaaaaagt aaaccagatt ctttctggca tctctaacga tgaacgaacc aaaattatgg
    17881 accaagcagt caaagatcag cctgctgcaa ctgatagtga agaaaaacct ggcatcattt
    17941 ctgatttcac tacgatttgg aaacaatacg gcaatatgtt cttacgaggt gctggactta
    18001 ccttgttcat cgcattgatc gggacagttg tcggtactac acttggatta ctgattggtg
    18061 tcttccgttc ggtacctgaa tcaggaaatg cactgactcg cttcttccaa aaaatcggaa
    18121 atgcacttct ttctatctat gtcgaagtat tccgcggaac accgatgatg gtacaagcaa
    18181 tggtcatctt ctacggtctg gcactcgctt ttggcatttc attgaaccga acgattgccg
    18241 ctttgtttat tgtctctctc aatactggag cttacatgac agagatcgtt cgtgggggga
    18301 tttttgcagt agatgaaggg cagttcgaag ctgcgcaagc cattggtatg acccatggcc
    18361 aaacgatgag aaaagttgtt attccacaag ttttacggaa tatcttgcca gcaacaggaa
    18421 atgagtttgt tatcaatatc aaagatacag cagttttaag tgtaatcggc gtagctgatt
    18481 tgttcttcca aggaaactct gcttccggtg cgaatttcca attcttccaa acatttacga
    18541 tcgtcgggat catctactta gtcatgacct ttacgatcac cagaatcctg cgggcggtag
    18601 aaaagaaaat cgatggtcct tcagcttata ccaagcttga agaaatcgac aattcaaatt
    18661 tgcaggaata aggaggaaga atcatgaatg aaaaaattat tgaaatcaaa catctaagaa
    18721 aaagcttcgg tgaaaatgaa gtattgaaag atatcagcgt aacagtcaat aaaggtgaag
    18781 ttgtgacgat catcggttct tccggttctg gtaaatctac tttcttgcgc tgtatcaatt
    18841 tactggaaaa accaacaggc ggcgagatca tttataatgg agaaaatgta ttagctccta
    18901 aatataattt acctaaatat cgaacgaatc taggtatggt tttccaatcc ttcaacctgt
    18961 tcaacaatat gaatgtcttg gaaaactgta tgtctggtca aacaactgtc ctgaaacgag
    19021 ataaagaaac tgccaaaaaa gtagcaatcg aaaatctgga aaaagttggt atggatcgtt
    19081 atatcgaagc caaaccagca caattatctg gtggacagaa acagcgtgtc gcaattgctc
    19141 gggcattatc aatgaatcca gatgtattgc tattcgacga acctacttcg gcgttagacc
    19201 ctgaaatggt tggcgaagtg cttaatacga tcaaagactt agcacatact ggcttgacaa
    19261 tgcttatcgt gacgcatgag atggaatttg caaaagatgt atctgaccgt gtcattttta
    19321 tggataaagg tgtgattgca gaagaaggta caccagaaga tatctttgtc catccgaaag
    19381 aagaacgtac aaaagaattc ctttcacgta ttttaaatgc ttaggatcaa tagctgattg
    19441 ggacaaagag ctgcggtgtt taccgcagtt cttttttatg aattactcat aaaaggtaaa
    19501 tttct
//
LOCUS       DBBGRF010000054        18977 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000054 DBBGRF010000000
VERSION     DBBGRF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.054"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..563)
                     /locus_tag="ACIZD4_002249"
     CDS             complement(<1..563)
                     /locus_tag="ACIZD4_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HGC5991137.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(750..1400)
                     /locus_tag="ACIZD4_002250"
     CDS             complement(750..1400)
                     /locus_tag="ACIZD4_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991138.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="ACIZD4_002251"
     CDS             complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="ACIZD4_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGC5991139.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2912..3910)
                     /gene="yvcK"
                     /locus_tag="ACIZD4_002252"
     CDS             complement(2912..3910)
                     /gene="yvcK"
                     /locus_tag="ACIZD4_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HGC5991140.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="ACIZD4_002253"
     CDS             complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="ACIZD4_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGC5991141.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTNRDKDKRKETVNRS"
     gene            complement(4926..5657)
                     /locus_tag="ACIZD4_002254"
     CDS             complement(4926..5657)
                     /locus_tag="ACIZD4_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HGC5991142.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(5661..6926)
                     /locus_tag="ACIZD4_002255"
     CDS             complement(5661..6926)
                     /locus_tag="ACIZD4_002255"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HGC5991143.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="ACIZD4_002256"
     CDS             complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="ACIZD4_002256"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGC5991144.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="ACIZD4_002257"
     CDS             complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="ACIZD4_002257"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGC5991145.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            12268..13770
                     /locus_tag="ACIZD4_002258"
     CDS             12268..13770
                     /locus_tag="ACIZD4_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGC5991146.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13772..14509
                     /locus_tag="ACIZD4_002259"
     CDS             13772..14509
                     /locus_tag="ACIZD4_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGC5991147.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(14680..15873)
                     /locus_tag="ACIZD4_002260"
     CDS             complement(14680..15873)
                     /locus_tag="ACIZD4_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5991148.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDRKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVLENDTKKKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQQVMKKRPKAEPFVIDGRGNFLFVNHKGKPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(15952..16158)
                     /locus_tag="ACIZD4_002261"
     CDS             complement(15952..16158)
                     /locus_tag="ACIZD4_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HGC5991149.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            complement(16151..17293)
                     /locus_tag="ACIZD4_002262"
     CDS             complement(16151..17293)
                     /locus_tag="ACIZD4_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC5991150.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRYPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CDGVIRRFDLAINDMCGLLDIPVLSEKYRNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRGTKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
     gene            17805..18440
                     /locus_tag="ACIZD4_002263"
     CDS             17805..18440
                     /locus_tag="ACIZD4_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5991151.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            18594..18671
                     /locus_tag="ACIZD4_002264"
                     /pseudo
     CDS             18594..18671
                     /locus_tag="ACIZD4_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            18916..>18977
                     /locus_tag="ACIZD4_002265"
     CDS             18916..>18977
                     /locus_tag="ACIZD4_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="regulates the transcription of tet(M) by
                     attenuation; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HGC5991152.1"
                     /translation="MILKYPENICMLCMPMVMHK"
BASE COUNT         5492 a         3987 c         3315 g         6183 t
ORIGIN      
        1 tctataaaca tcaccccaaa taaaacagaa aacagtataa gcattataaa aattatcaac
       61 aaccttgatc cttcttttat agattcagga aacagtataa ttttagtact agataaattg
      121 tttacaccga ttagtgttaa aatatcttta ttcttcttgc taacataacc ctttatgcac
      181 aaaagaacag ctatacttaa agtaacaaat aaataacgta ttccaataga aaaatcacta
      241 taaatactct ctagcatagg accgacaatt gaagaagtca ctactgcaaa tgctggacct
      301 atccaagcaa cattagaatg ttctttctct cttttccttt gtaaatcttt gttgagtatt
      361 aatctattta tttcttctgc aggcaagtta attttcataa ccttatgggg gattatccaa
      421 ttaaaaatcg gaaaaaggta gcctccccaa aaagtatagt gatctgtgtc aatcagataa
      481 taacctgatt ttgattccag aataacatat ctcaaagccg aacgaaaatt tttcatgaat
      541 atccataatc tcactgtttc cacacctaat tcctccaatt ccaattaaat ggatttatag
      601 catcaccaat tatgttaact gcctgaccaa cctcattgat aaaattggca ccactatccc
      661 atgcttcaac aatgctatat atctatcaaa caaaaaatgg aaaactaaat actcgcgcac
      721 ataaatttta cattctgttt tttataagac taataataat cattgaaaaa atttcttatc
      781 ggtggcgcat attcccaatt gattaatgtg atcccatatt ctgcaagtat tttacgagct
      841 tcttctaagt catagtgaga aaaatgcata aaacctgcaa tacgatcacg gactgtgagc
      901 tgtggcttgc ttccaccatc attcataaaa tatccagcag agccactact taaagtgatt
      961 gttacatctt cactttctat tattaagaat tcataatgaa atgctttcaa ctctccacta
     1021 ttatttaaaa gttttatact ccaacttcgt ctaggttgag ttgtcacatt ccctctaaaa
     1081 cttcctataa attctgcaat caccgtatct tcaatcaaaa ttctttcctc atctatttca
     1141 tattcaagac taaacggaaa ttctccatat gtaatctctg gcaatggtgg tgctgtagtt
     1201 ctccaaataa atacaataac tgtgaataga aaaaatccaa cgatcgatat aaatgttatg
     1261 agacctgctc gaagtaaaac ccgatataat aaaaatgctg tatttcgctt tgctatatct
     1321 agaaaaataa aaagtactgc aatcataatg atagtaaaag ttgtaaaaaa gcacattttt
     1381 tgccctccct ttataaacat cgattctcaa attctaaacc aaatcttgat agttcaagtt
     1441 caggtataac gtataccaac catacatccc aattactatt tatgaactta tgattatcac
     1501 tgaataaatc actccatccc cttgttaaaa cttctacatt aattacacct ggttgttttc
     1561 gactagctaa tccaatgaac ttatcaacca tccttatcca ccaaccacga gaatcttgac
     1621 cagaagtaag aaaaacagtt ctcaaggttg atcgagcagt tccttccagt ttttaattaa
     1681 tctccagtta tagataaata cttgatccta tctatatcag gacttctata ttaagcaaaa
     1741 gtttatgtat aaaactaaaa tcttcattca gttgtctccc cgctttttat acgattgtat
     1801 taaaaaacaa tagaagcctt tcaacattat gttactccag taaagttgga attatagttt
     1861 gacggaagaa aagcaagtat agcttttaaa aaaaactgat acattcgcat ctcctgcttc
     1921 atgtatcagt tttttctttg gattaaactg cttcttcacg cagtttttcc gcaaattcat
     1981 ttattttgcg aattcggtga ttaattcccg attttgatat tgcacctgag ggaatcattt
     2041 cccctaattc tttcaagctg acctctggat gttgaagccg aagttctgcg atttcctgaa
     2101 gtttttcagg aagggcatgt agaccgacct ttgcttcgat caattcgatg ttttcgattt
     2161 gtttagaagc cgcatcaatc gtcttgttca gatttgctgt ctcacaattg actagacgat
     2221 tgaccgaatt tctcatatcc cgtacgattc gaacatcttc aaatcggagc attgagttgg
     2281 ttgcaccaat caatgttaag aaatcagcaa ttttttctgc tccttttaaa tacgaaatat
     2341 agccattgcg ccgttcaagc gttcgagcat gtagaccgta ataatttaac atatcgcaaa
     2401 tgtcttggtt atgctgttca taaatagaaa atatttccaa atgataacga ctcgtttccg
     2461 gattattgac tgaacctgag gccataaaag caccacgtaa gtaagaacgc attttttgcg
     2521 aatttcccat aatctcgtcc gaaacgtgtc cattgaacat cataccatcc atgatatcaa
     2581 gatccatcaa cacatctttt gtgccttgct tcaaccggac gatatagaca ttgttctttt
     2641 ttaatttcat ttttttacga acgagtagct cacttcgtac ctgataatga tctttcaaaa
     2701 gagaatagat acgtctggca attgcagcat tttctgtttg gacgttcaaa ataaactgct
     2761 ggttcacaat acctaaagag ccgttcattc gcagcaaagc agctaattcc gctttcgcat
     2821 gttctcgatg aacttccaaa ccagttagtt ctttcttcac atctgcagca aatgacatcc
     2881 tattctcctc ctttctccaa caataaattg cttaatattt tgaaccgaaa actaaacgga
     2941 acaattcttc tactactttg tctccatcgt ggaagacacc accatctttc aattctaaaa
     3001 agtcggtgga aatcactcga catccttcat ttctcaatcc gttgaagtcg tgtgcgactt
     3061 gtactagata ctcatcatag atctctgggt ccatataatc ttcaggcact ttttccgtat
     3121 tgaccaatac tgtatcgata aaaggctgat tcaaatgctt gtgtaaaaca cgtatatgat
     3181 cggcatctgt gaaatgttcc gtttcccctt tttgggtcat gatattacag atatagacgg
     3241 tttcagcagt tgtcttgagc attgcttcgc cgatttctgg tatcactaaa tttggaagga
     3301 tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc ggcgtccata attgctgaaa
     3361 cgacttttcg agccgctttg gcttcacttt tatcatttgt gttgcagaca tacacacggt
     3421 caatggtttt acggttgatc gcgattttag attctcctac tgcagtcgtt ccgtctttaa
     3481 aaacagcatg caaggtcaaa ggagtttctg aagaaggata aacatgtcca tctacatgca
     3541 tcatttttgc taataattga atcgcctcat aagtgcttcc ccgcatctcg gaaactgcgg
     3601 caatgatcag attaccgatc gtatgattgg ctaaaaactg atcttccttt ttgaaacggt
     3661 attggaaaat atcttcatag aattgtggca tatccgataa cgccactaag acatttctca
     3721 agtcaccagg aggagccata gcgatcgatt ctctgattgc accgctgctt ccaccatcat
     3781 ctgcaacagt cactactgct gtgatatctg ctccttgatt tcgtaaactt ttcaggataa
     3841 ctggcagacc agtgccaccg ccgaccacta cgatctttgg ttttcttatc cggtaggttt
     3901 tcattttcac gaccggttca ccgtctcttt ccttttatcc ttgtcccgat ttgtcacatt
     3961 gactttatag tttttcccta aagcatttgc caaacgttca gtcaatgcca cagaacggtg
     4021 ttgaccgcct gtacagccga ttgcaactgt caagctgctt tttccttctt taatgtatcc
     4081 aggcaataca gtttccagaa gatccaaaaa tttatggtag aatgattgcg tttcatcaaa
     4141 ggacatcaca taatcataga ctggctgatc ttttccggtc aatggtctta gttccgggat
     4201 ataatgaggg ttgggcaaaa aacgcacatc catcacaata tccgaatcga tcggcaaccc
     4261 gtatttaaaa ccaaatgata caaattcgat ccgaaatcct tggtctccct ttgatttgaa
     4321 tgactcattg attttttcac gtaattgtcg tggtgtcaat gttgtcgtat caatgatcac
     4381 ggaagcttgg gctttcaagt cgtctagtat cgcccgttct ttacgtatcc cttcagtgat
     4441 caaaccgtcc atcgccattg gatgtgctcg tcttgtttct ttgtagcgag ccactagttc
     4501 ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg aagttcgtat tttcgatttc
     4561 gatcagcatg ttttggattt cttcaaagaa ggaacgagaa cgcaaatcca ctcctaaagc
     4621 catttttgtg actttacctg attctttgat caattcccag aattttggaa tcaatcgagg
     4681 cggcatatta tcgatacaaa aatagcccat atcttcaaaa ctttggatag ctactgtttt
     4741 ccctgcacca ctcatacctg ttatgatgac taattgcaaa ttatctgtca tatttacgaa
     4801 cccctctcac attgtgcata ataaaattat atcatcccgg gcgtatcatt accagttttc
     4861 tttttctttt acaaaaagat ttggaccaaa tatcttttag gatatttgcc ccaaatccaa
     4921 tttttttact tttccgatgc tgtatccaat gcctcgcttc tttcagctaa tgcacgttcg
     4981 atcgttcgat ccgctaaaat agattgagca tcgatcactg ggtaatgatt atcttcagca
     5041 aattcatgca tcaaagataa ttctgtgcaa cctaggatga ctttttcaca gtttaggcgc
     5101 tctaccgctt cctctaagat ttcgtaatag agctcttgat tcaaataatc cgattccttg
     5161 atctcatgat agatcaggta attgattttt tcttgaagcg cagtatcagg aatcactgtt
     5221 tcgaaaccaa gatttttgac ttcgcgttca tagattccag ctttcatact tccttctgtt
     5281 cctagaatcg ctactctccc tgtcgtatgc tgacggacaa gttcatttgc tgcttctctt
     5341 ggcatatgca agataggaat atccgttgcc gcttgtaact cttcaaaaaa gtagtgtgcg
     5401 gtgttacaag tcaacacaat gaagtttggt cgcaataaat tttgtttctc aatatcatcc
     5461 agcagaaacg gcattggatt ttcttctgat cgatctaaaa tataagctgt acgatcagga
     5521 actgttgcat gattgaataa gacataattc aaatattctt gatcttttgt agctttcgtt
     5581 cggtggttga tcaagcgaac aaaactttct gtcgccatcg tgcccattcc gcctaaaata
     5641 ctgaaaaaat tctccatgaa ctagccttct ttcacatgaa aatacttttt gaatcttgga
     5701 atatagttat ggaacatata tttcatcaac aaccagcgct tgattgatcg gtctttttca
     5761 taaaatacag tagtaccgta acgattttct ttgatcattt gctcagctag ttttttgtct
     5821 tcattttccc gagcatattc taaaaagatt tttttgggca cacccatcca taatcttgct
     5881 ttatctgatt gattcgttcc ataggtcgtt tcaacaaagg gtttgttgaa cactcgatct
     5941 tctgtgacaa aacgagccag attcaagccg ttcaatgtca caaagaaact gctacgacct
     6001 tgtctcaaat tgatttcaaa taatttatat tctccatctc taggatcata cttcatatcg
     6061 aaattggcaa agcctgtata ttcgattttt tccaaaaatg ccttaatggt ttgatagatt
     6121 ttttcgttat aatctggcat gatcacaacg taattaccaa tcgatgctgg tgtaggatct
     6181 tctaatagtg gatgaccaag gcacatcatc cgaacttgat gatcttcatc tacatacgca
     6241 tttagcacac gcatattact atcatcaccc gggataaaat cttgtacaat catttcactt
     6301 ttataaccgg cttcgtatat ccggcctaaa attaaatcga actcttctct agtctctaaa
     6361 ataaaagctt tttttcttcc ttcaaattgg acagaaagat actccacact gtttgcaggt
     6421 ttcaaagcaa ctgggaattc aaaaggcaat tcctgttcca aatgtccatt tactaacatt
     6481 tcttctctga cgatcaatgt tttaggatac ggaagatcat attcttcaca aacttcataa
     6541 aagcttactt tattgatcag cctttcaaat aaagaataat caatatatgg acagataaaa
     6601 tattctgaca gctcttgttt atgttgggag atcaattctg catatccatc accacaagca
     6661 atcaaaagat attttttact cttatcagaa tatctttctt ttgccaaacg aagcatcgtc
     6721 tcgataaata cagggtcttt atcaaatcct ggaataactt ctacattgac aattttactg
     6781 tagcgggtag gggctaactg atccgaagca tatgcttggc agattttgcc gtatgcttca
     6841 ttaaaagaac gtgccatacc ataaacgttc atgtcgcttc ctaataatat agggataaat
     6901 tcttcatttt caatactgtt catcattatc tctcacttac tcataatctc ttgtttttct
     6961 tttccaacta cacaaggaat atcataccat aaagaaaaaa gcaatcaaag gaaagtcctc
     7021 cgattgctca attctttttt gaacggattg aacttatagg aagtttttat ctataccaat
     7081 cagtgtagaa agaactacca tgtaatgatt ctagaacact gatattaata aaacaagcaa
     7141 aaattcattt ttttatgttt ttttaactat ctcagctatc tatcctcttt ataccattat
     7201 ttttttcaaa tagtgacctg tataactttc ttttacgtta atgatttctt ctggtgttcc
     7261 agtcgcaagg atcgttcctc caccttctcc accttctggt cctaaatcaa tgatataatc
     7321 tgctgttttg attacatcta gattgtgttc aatcactaaa actgtgttac cagcatctac
     7381 taatctttgt aatacatgca acaagcgggc gatgtcatcg ctatgaagtc ctgtcgttgg
     7441 ttcatctagt atatagaaat tctttccatt agagattttg tgcaattcac tggcaagttt
     7501 catccgttgt gcctcaccac cggacaatgt cgttgctggt tgccccatcg tcacataacc
     7561 taagccaaca tcaacaatcg tttgcagttt gcgatgaatc tttggaatgt gcttgaagaa
     7621 ttctacagca tcctctactg tcatttccaa aatatcagca atgctttttc ctttgtaatg
     7681 cacttctaat gtttcagaat tatatcgttt accatgacat acttcacaag gaacatagac
     7741 atcaggcaaa aagtgcattt cgatcttaat aattccatcc ccgcgacaag cttcacaacg
     7801 accgcctttt acgttgaaac taaaacgccc tttcttataa ccccgcattt ttgcctcgtt
     7861 cgtttgagca aataacccac ggatatcatc aaatacactt gtataagtcg ctggattact
     7921 tctcggcgtc cggccgattg ggctttgatc gatatcgatg atcttttcga tactttcgta
     7981 gccggaaatt gtcttgaatt tacctggctt agcagaattc ttatttaatt tttgcgctaa
     8041 cgatttcttt aagatactat tgaccaatgt actctttcca gaaccagaca cacctgtgac
     8101 tgctacaaat tctcctaatg gaaattcaac actaatattt ttcagattgt tttctgaagc
     8161 accagtgatc ttgattgctt tcccattacc tttacggcgt tcttttggta cagggattga
     8221 ttttttccct gaaagatatt tccctgtcaa agaattttca tcattagcta cttcttcagg
     8281 agtgcctgca gccacgattt gtccgccttg ttctccggcc ccaggtccga cgtcaatcaa
     8341 ataatctgct gcccacatcg tatcttcatc atgttcgact acaacgaggg tgttgccaag
     8401 atcacgcatt ttctttaatg agccaatcag tcgatcgttg tcgcgttgat gcaatccgat
     8461 cgatggttca tctaaaatat acaaaactcc agaaagattc gatccaattt gtgtagccaa
     8521 tctgattcgc tgcgcttctc ccccagataa tgttccggaa gcgcgactca aagttagata
     8581 gtctagtccc acattttcca agaatgaaag tctgtcattt acttctttta aaatcggttt
     8641 ggcaattact ttctcttgtt cagataacgt taagtttgag aagaaatcta ctgctttttg
     8701 aatagacaac tcatttgttt gcccgatatt cgttccattg atttgaacag atagagcttg
     8761 gggattcaat cgataacctt tacatgtctg acaagttaat tctgtcatat aaagacgcat
     8821 ttgctcacgc gtgaaatcac tgttcgtatc atgataacga cgctcgatat tcttcaatac
     8881 cccttcgaaa gtcgtttcta catcgcgaac gccaccaaaa tcattttcat aatggaaatg
     8941 gaaaagatca tctgtcccat tcaagatgat ctcctgatgc tcttccggta attcttcgaa
     9001 tggtgtatct aaatcgatac cgaaactttc acaagcctgc gctaacattt gaggataata
     9061 ctgagagctg attggattcc atggaacgat agcaccttga ctaagtgtct tcgttctatc
     9121 tggaatcact aaatcttgat cgacttctaa tttgacacct aaaccatcac agtctggaca
     9181 agctccaaaa ggcgcattga atgagaacag tcttggttct agttcgccaa cagtaaatcc
     9241 gcaataagga caggcatagt gttcgctaaa caacatttct tcttcaccga tcacgtcaac
     9301 cagagcatag ccgtctgcta atcgcagggc cgcctctaaa gaatcaaata ggcgagaacg
     9361 aatcccttct ttcacaatga tccggtcgat gacgatcgcg atatcatgtt ttttgttttt
     9421 ctccagctca ggcacttcac ttaaatcata gatctcacca tcgactcgaa cgcggacgta
     9481 tccctctttt tggattcgtt cgaatatttt tttatgttgt ccttttttct ttaccacgat
     9541 cggtgccaac acttggatct ttgtgcgctc aggcaaagcc attacttgat ctgccatttg
     9601 atctactgat tgactggtaa tctcgatatg atcgttggga caaatcggat gtcctacacg
     9661 tgcaaacaac aagcgtaaat agtcattgat ttccgtcaca gtacctactg tcgaccgagg
     9721 atttttactt gttgttttct gatcaataga aatcgccgga ctcaatccgt cgatgctatc
     9781 tacgtccggc ttatccattt gtcctaaaaa ctgacgagca taagcagaaa ggctctctac
     9841 gtatctccgc tgcccttcag cgtacagcgt atcaaatgct agggaacttt ttccagaacc
     9901 ggacaaacct gtaacgacca cgaatttatc tcgtggaatc gttacatcta tatttttcaa
     9961 gttatgggca cgtgcaccat gaatcgtaat tttatcgtta gccatgttgt cctcctactt
    10021 tgaagctttt aattctaaaa tcatatctcg cacattcgcg gctgtttcaa aatccaaagc
    10081 ttttgccgca tctttcattt ctttttctaa tttcatcaat aacgtgtctt tttcttcctt
    10141 cgtcatttct tcgtacgaga cttgtaccgc ttcttttgta tcatcttccg attctttcgt
    10201 aatagaaatc aaatctcgga tttctttaat gatcgttttt ggaacgatcc catgttcttc
    10261 attgtacttc tgctgaatcg tacgacgtct tgacgtttca tccatcgcta gacgcataga
    10321 atctgttact ttgtctgcgt acatgattac tttaccttct tcattccgag cagctcgtcc
    10381 aatcgtttgg actaaggaac gttcactacg taaaaagcct tctttatccg catccaagat
    10441 agcaacaagg gaaacttcag gtacgtctaa tccttcacga agcaaattga ttccaactaa
    10501 cacatcaaat tcacctaatc gaagatctcg aatgatttct gttcgttcca gcgttttgat
    10561 atcactatgc aaatatttga ctttgatccc taattctttg aaataatctg tgaggtcttc
    10621 tgccattttt ttcgtcaatg tcgttacaaa cacccgctgg tctttttcga ctcgttcatt
    10681 tatttcgcct actagatcat cgatttgtcc catgattgga cgaacttcga tcactgggtc
    10741 aagcagccct gtcggacgga tgatttgttg gataacggta tctgtttgtt catgttcata
    10801 tggtcctggc gtcgcagaga cataaatgat ctgattgaca tgtttttcaa actcttctaa
    10861 ccgaagtggc cgattgtcta aagcagatgg caaacggaaa ccgtaatcta ctagcatctg
    10921 ttttctcgct cggtcaccat tatacattcc tctgatttga ggcatggtta cgtgcgattc
    10981 gtccgccacg atcaaaaaat cttcaggaaa gaaatccaat agcgtataag gcggttcacc
    11041 ttctttacgt ccgtccatat gccgagaata attttcaatt cccgacgtgt agcccatttc
    11101 taacatcatt tcaatatcgt aattggttcg ctgttctaaa cgttgagctt ccagaagttt
    11161 gttttcattt cgcaagacag ttaaacgctg ttctaattcc tctttgatat tcgctacggc
    11221 atgctccata tgttcatcat tcgtcacaaa gtgagtcgcc gggaagattg ctacgtgttc
    11281 cgtttctcct aaaacttcac ctgtcagtgc attgacttct cggatacgtt cgacctcatc
    11341 tccaaaaaac tccacacgta aggcacgttc atctcttgaa gccggaaaaa tctccacgac
    11401 atcaccgcgc actcgaaaac gaccgcgctg aaaatctata tcatttcttt cgaattggat
    11461 actgactaag tcacgaatca actgattgcg atctagttct gctccctgtc gaatcgaaac
    11521 tacttgtttt tggtactcaa aaggcgagcc taatccaaaa atacatgaaa cggatgcaat
    11581 gacgatcaca tcatttcttt ctaataatga actagtagcc gaatgtcgta atttgtcgat
    11641 ctcatcattt acacttgaat ctttttcgat atacgtatcg cttgaaggca cataagcttc
    11701 aggctgataa taatcataat aagaaacaaa atattcaaca gcattgttag ggaaaaattc
    11761 cttgaattcc ccgtacagct gaccagccaa tgttttgtta tgggcaataa tcagtgttgg
    11821 tttattcact ttctcaataa gattggaaat cgtatatgtt ttccctgttc cagtcgcacc
    11881 taataagatt tgtgcttttt tcccgccgac tacgccatcc actaattggt taatcgcttc
    11941 aggctgatca ccagccggtt ggtatttcga gacaagctca aagtgtcggg aggtatctct
    12001 ctcaatcatt cttcgtcctc cttttcattc attccttttc attttacgac caataaaaag
    12061 aaaaggaaag caaaggcatt ccttactaaa aaattatacc acaccgaaca tactttcgcc
    12121 acttttttat cttattatac atgttatgtt ttataacata aaatgttaga aactcgcatt
    12181 tttttcattt tttcgagctt acagtcttgt ctgattcagc acttttcgcc tataataata
    12241 aaatattgga aatttaggag gttgattatg aaaagaaagc atttatttca ctcatttgtt
    12301 ttcttaatga caggacttgt gacacttgcg tttggtcatg ttgcacaagc tgacaacact
    12361 acaacggcag agtcaagcac aagcgagaca atgcaaaaaa tagagcccaa aaaagacgta
    12421 tacgtaattg ccagtgactc tgcttttgct ccatttgaat ttcaaaacgc aaagggcgag
    12481 tacgaaggca tcgatgtaaa attgatggaa aacatcgcca aactgcaagg atttaacatc
    12541 cgaatggact accgtggttt ctctgctgct ttgcaagctt tggaatcagg acaagcagac
    12601 ggaatgattg ccggaatgac tgtaacagat gaacgaaaga aaagctatga tttttctgat
    12661 tcttactttg atagcgggat ccaattagct gtcaaaaaag gagatacttc gatcaagtct
    12721 tatgaagatt tgaaaggaaa aacagtcgga gcaaaagttg gtaccgaaag tgctgaattt
    12781 ttaagcgacc atgaatctga atatggctat tctatcaaat attttgatgc tgctgatcaa
    12841 ttgtacgacg ggttaaaagt tggcgcaatc gatgcaatga tggatgatta tccggtaatc
    12901 ggttatgcga tcaaacaagg acaagaattg gaaacaccga tcaaaaaaga atctggcgga
    12961 aaatatgcat ttgccgttaa aaaaggacaa aatcctgagc ttcttaatat gttcaatgaa
    13021 ggattgaaag aattaaaaag aacaggcgaa tacgataaga ttattaaaga atatgtagcg
    13081 gatggttcag aaacttccag tgagtcttcc actgctgatg aatcaacatt tcttggactt
    13141 atccaaaaca actatcaagc attgttgaaa ggactttgga gaacaattct cctaactttg
    13201 atctcctttg ctttggctat agtaatcggt gtgatttttg gattattcag tgtagcacca
    13261 atacgcgctc ttcgcacaat tgctagtatt tatgtcgata tcatccgagg aattccaatg
    13321 atggttcttg cgttctttat tttctttggg ttgcctggta tcgttggatt tacgattcct
    13381 gacttccttg ctggtgttat caccttgact cttaacgcaa gtgcttatat cgcagagatt
    13441 gttcgaggcg ggatcaacgc cgttcctgtc ggacaaatgg aagcttccag aagtttaggt
    13501 ctttcttata atcggacaat gcaaaaaatc attttgccgc aagcgatacg catcatgatc
    13561 ccatcattcg tcaatcagtt cgttatctca ttaaaagaca caacgatcat ttccgcaatc
    13621 ggtgtagtcg aattgctgca aactggtaag atcattgttg cacgtacaac acaaagtacg
    13681 tatgtttact tgatcattgc gatcatgtac ttgattttga tcacagcatt gacaaaatta
    13741 gcaaaagttt tagaaaagaa ggtgaagtaa gatggcagaa aaaatcttag ttgagcattt
    13801 agtcaaaaaa tacggcgata acacagtatt aaacgacatc aatgtatcca tcaacgaagg
    13861 agatgtcgtc tgtatcattg gcccttcagg ttcaggaaaa agtacattct tgcgttgctt
    13921 gaatcgttta gaagaacctt ctgacggtga aattattatt gacggcgccc acttgatgga
    13981 taaaagcaca gatatcaact tggtgagaca acatatcgga atggtattcc aacactttaa
    14041 cctattccct catctttcta ttttggaaaa catcatttta gcaccgatgg acctgaagaa
    14101 agaatctaga gaagaagcag agaaaaaagc aatcaaatta ctgcagacag ttggtctaga
    14161 agataaaaaa gatatgtatc ctgaaatgct ttctggtgga caaaaacagc gtgtggctat
    14221 tgctcgtgct ctagcgatga accctgacat catgcttttt gatgagccta cttctgcact
    14281 cgatcctgaa atggtcggtg atgtcttgaa cgtcatgaaa aagttagcag aacaaggtat
    14341 gacgatggtt atcgttacgc acgaaatggg gttcgctaaa gaagtggcca atcgcgtcat
    14401 gttcattgac gacggaaact ttttagaaga tggaacgcct caacaaatct ttgaaaatcc
    14461 gcaaaatgaa cggacaaaag atttcttgaa taaagtatta aatatttaaa ataaattata
    14521 tatgtctttt tgactatctt tttatatctt cttaaatgtc cgcaaagcct tattttatag
    14581 gctctacggg cattttgctt ttgtggtaaa cctcacatat ctaggtctat cttcttatat
    14641 tttcactatc aagcgtggtt aaaatcgtgg taaatacttc tatgcaatta gacgctgaac
    14701 ctctgatttt gcggtatcta tggacgcatg agcataccag ttcattgtga tactgatatt
    14761 tgaatgcccc atgatatact gtaaatcttt tgggttcatg ttcttgcttg ccagtcttgt
    14821 gcagaatgta tggcgtagcg tatgcggtgt gatatgtggc aatggattgt ccttgtggtg
    14881 cttgttgtat ttctttacca tacggataaa taaggcgtta taatcaatcg caactttggg
    14941 cttgccctta tgattgacaa ataggaagtt gccccgtccg tctatcacaa atggttctgc
    15001 ctttggacgt tttttcataa cctgttgaaa tgcctgtatc gtttctttgc ttaatggtac
    15061 ttgccttatt ccgctttttg ttttaggcgt ttcaatataa tagccctgtt ccttgctctt
    15121 tagtaactgg tggtcgataa tcacaacttc attcttgaaa tcaatgtcgg ctactgtcag
    15181 tccgcacagt tccgaaatac gaagtcctgt ctttaacagt atcagcacat catcataatg
    15241 cttgtgatac acattgtccg tcttgatgaa tgagagtaag gcttgttcct gttcctctgt
    15301 caatgcgact ttctttttgg tatcattttc taggacttca ctcaacttga aatcaaaggg
    15361 atttttcctc acataatcat cttgaatggc tatgtagaat gacgctttta acgagcgttt
    15421 atggttgtta atggtattgt aggaaaagcc tttgtctttc atgcgtaacg cccattcctt
    15481 agcgtcagag ggtttgattg tatcaatgct cctagcacct aacttgtcct ctttcaataa
    15541 ccgcatgagt tgttcccgtt gtttctgtgt gcttttcttc acatttgccc tctgtgcgtt
    15601 ctgtttggca taaagttggc aaagcgtcat tttcttgcca gtgctgtcga taccgtcctc
    15661 aatatcccgt cttatctgct gttccagttc tcgaagtgag ggtttttccc gttttccctt
    15721 tggtgtcggg tctgtgggtg tcaatctcca agcatacaca tattttgtgt ttccaaatgc
    15781 gtctacatat ttatataagt attttctgtc tgttcgttgg ctctctccag tatgcaggat
    15841 acgacctttg ttatcccgtc ttttttcttt catggtgtct gctcctttcc ttgttggaaa
    15901 gagccttgat atgacttgtg ttcatcataa cacatacaag gctcatttgc attagatagc
    15961 gtccaattta tcaatgacct gttcaaactg tcggcgttta atctgtatgc ggttgccatt
    16021 cataatgagc cagccagcgt ccttgttttc ctctgccaat cgtcttaact tgttttctcc
    16081 gatacggaaa tactttgacg cttcttcaat ggtaagggtg tatttttccc atacgggaat
    16141 atcctgtgca ttactcataa aacaccccct cactttcgat tacgtctgct atgtccgtac
    16201 acatctgttc cacaagcatt tcctgctttt cagagaggtg ggtacattca tcaatcattt
    16261 tcatgtagtt tgagcctgtc agcctgtcga tttcctctat catcacgatt gacggcatga
    16321 cctgtctttc cagccattgc agagtgcgtt ccatattgac aggtacgggg ttcatttcaa
    16381 aaggtaaact gtcatgggaa atgaatatct cccacagcgg atagtcggga aattgcacaa
    16441 aatcagtaat aaggtaaaac accagcccat gagggttata tgtcaataac aattcctcaa
    16501 ctgcctgtac tgcttttgta ccacgcagac gaatttcaaa acgattgata atatccgtat
    16561 gtttcttttt ggttgcctgt tccttttgtt tttcatacag gcagaagtat tttgtgcttg
    16621 cctttgaacc gatataaagg gtgcttgcta aattacggtt ttttccgctt agttttccac
    16681 cctgcacatt ttcataattt ttacagcgac aatccgcacc gccatttctg tatttttcag
    16741 acaaaacggg aatatccaac agaccacaca tatcattgat tgccaagtca aaacgtcgga
    16801 taacaccgtc acagtcaaga cagcggttta aaaatgaata ccaatctctg ttctgtgcct
    16861 gcaagacata ttccatgttg cgtgagcctg ccccttttaa ttccaagaat acgcccatgt
    16921 gttcgtcatc agaagccatg accttgattt ctccgtaggc gtaatgctct ttatagccat
    16981 aatacccata gtcataatgg ataaaataat ctgctttcat gccaagcacc tttcggataa
    17041 tttccaatgc gtcagtcgtt ggataacgga cagacagata atcaacgagc agataaaaag
    17101 gcttatcgca gatataataa ttcagacaac gcaggataat attttgtgtt tccttgctgg
    17161 cgttggcttt tccgttctca aagcggttga tactatatct tgatacatgg gtaagacttg
    17221 caagttctcc ttgtgaaaga ccgcttgcaa gacgtttgtt cttcatttca agtgcaaatt
    17281 ctaaattgtt cattgtattc ctccaatccc acaatagcct tgaaatacct gtaaacctct
    17341 attcaaaaag tgtgatatgc actatcttct taaaacttct cattactact cacaactttg
    17401 ggattgtatg gtttttgact tgtcttttgt gaaatagtgc ccccctgtta gataacgggg
    17461 gcacagacaa ggctcgcagg ctcgccagcc gacaaagcat ttcttcccct tgacacaagg
    17521 tgtcatggcg gtaagcctga gaggcttccg ccaccgtgtc agaaatactt tgtcagcaag
    17581 ttctgttttg ccttttctaa caagttccat ttcaaccgat attcatatct acggatttaa
    17641 tcagataggt atttcttttt gaatgttttt atatttcatt ctattgtgct tattcgatta
    17701 caagaacata gtaattctta tatgcttatt tgtcaatatc tttttttgcc tttacaaatc
    17761 atattaagca tgatagactt ataatagcga agatataacg agatatggag ggttatgcaa
    17821 tgaaaataag ccatttagga aataatatac agaccataag aaaatttagg ggaatgaaac
    17881 aacaggaact tgcggacaaa atcggtatca atatgcagag cctttccaag attgaaagag
    17941 ggttgaacta tcctgcctat gaaacgctgg aaaagataat ggaagtgctg gacgttacgc
    18001 ccaatgaatt gttgtcggga gaatggaagt atgtcaatca atctgaaaag gaagtctgtc
    18061 agtttttaag agccgaagaa cgtctaaatg cagaactgaa acatggacac tatgataact
    18121 tctttgacag cgaggaagaa tggctggaat atgagttaga aaagttacgg gaatatatta
    18181 cagactatat caacgggaaa agcattgaag cgtccgacct ttacccaatc aaagaattta
    18241 tccagcattt gaagtttcaa aaattattag accgctatga tgatttatac agtatggata
    18301 tgtttgggga aagcatagag ggacataagt ataagacacc ttatcaagtc gtgaaaatga
    18361 taaacccgaa ctcaaaagaa gatatggaac tgttacgaga agtattaagg aataacaatt
    18421 ttgatgatga ggacgagtaa cttttttcct cttgcgagaa gatacagcaa acaaaaagcc
    18481 cgatcaagag tgcaaagcac caccaatggt ggcaaagctc ttgacagggc tttttctttt
    18541 ctgttgtggg caatcaagag gaagaaaggg ataaaatctg atttgtggta aatcaggcaa
    18601 aggcaacgca ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt aattggaaga
    18661 ttatagaata acaaatattg gtacattatt acagctattt tgtaatcacg tactctcttt
    18721 gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt taagtatcta
    18781 tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag
    18841 tgggaacaaa taattggatg tcctttttta ggagggctta gttttttgta cccagtttaa
    18901 gaataccttt atcatgtgat tctaaagtat ccggagaata tctgtatgct ttgtatgcct
    18961 atggttatgc ataaaaa
//
LOCUS       DBBGRF010000055        18504 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000055 DBBGRF010000000
VERSION     DBBGRF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.055"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            99..746
                     /locus_tag="ACIZD4_002266"
     CDS             99..746
                     /locus_tag="ACIZD4_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGC5991153.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    875..1091
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1139..3784
                     /locus_tag="ACIZD4_002267"
     CDS             1139..3784
                     /locus_tag="ACIZD4_002267"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGC5991154.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4094..5407
                     /locus_tag="ACIZD4_002268"
     CDS             4094..5407
                     /locus_tag="ACIZD4_002268"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGC5991155.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5397..6050
                     /locus_tag="ACIZD4_002269"
     CDS             5397..6050
                     /locus_tag="ACIZD4_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC5991156.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6105..6797
                     /gene="radC"
                     /locus_tag="ACIZD4_002270"
     CDS             6105..6797
                     /gene="radC"
                     /locus_tag="ACIZD4_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGC5991157.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6947..7147
                     /locus_tag="ACIZD4_002271"
     CDS             6947..7147
                     /locus_tag="ACIZD4_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC5991158.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7401..9080)
                     /locus_tag="ACIZD4_002272"
     CDS             complement(7401..9080)
                     /locus_tag="ACIZD4_002272"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGC5991159.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9082..9294)
                     /locus_tag="ACIZD4_002273"
     CDS             complement(9082..9294)
                     /locus_tag="ACIZD4_002273"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HGC5991160.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9687..11417
                     /gene="efrA"
                     /locus_tag="ACIZD4_002274"
     CDS             9687..11417
                     /gene="efrA"
                     /locus_tag="ACIZD4_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HGC5991161.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11414..13174
                     /gene="efrB"
                     /locus_tag="ACIZD4_002275"
     CDS             11414..13174
                     /gene="efrB"
                     /locus_tag="ACIZD4_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HGC5991162.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13269..13466
                     /locus_tag="ACIZD4_002276"
     CDS             13269..13466
                     /locus_tag="ACIZD4_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991163.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13619..14104
                     /locus_tag="ACIZD4_002277"
     CDS             13619..14104
                     /locus_tag="ACIZD4_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HGC5991164.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="ACIZD4_002278"
     CDS             complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="ACIZD4_002278"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HGC5991165.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14981..15508
                     /locus_tag="ACIZD4_002279"
     CDS             14981..15508
                     /locus_tag="ACIZD4_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991166.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15599..16336
                     /locus_tag="ACIZD4_002280"
     CDS             15599..16336
                     /locus_tag="ACIZD4_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HGC5991167.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16340..17257
                     /gene="miaA"
                     /locus_tag="ACIZD4_002281"
     CDS             16340..17257
                     /gene="miaA"
                     /locus_tag="ACIZD4_002281"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGC5991168.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAVDFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17259..18488
                     /gene="hflX"
                     /locus_tag="ACIZD4_002282"
     CDS             17259..18488
                     /gene="hflX"
                     /locus_tag="ACIZD4_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGC5991169.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5984 a         3199 c         4022 g         5299 t
ORIGIN      
        1 atttgtctca cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt
       61 acactaaata tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac
      121 tgccaaaagc aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg
      181 actcaggtat aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg
      241 caacgatccg cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg
      301 atgtcccttt tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa
      361 tcgcattagt aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa
      421 atgaaaatct aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa
      481 ttgatggaga aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg
      541 tgacagtagc aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg
      601 tcaaaggaaa tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt
      661 atgtcaatgt tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg
      721 agaattactc agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa
      781 ctcgtcgtaa ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac
      841 ttgttgacta aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa
      901 ctggcacatt cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt
      961 gaaggtagct tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta
     1021 actcacttga gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat
     1081 acgtcctaga atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat
     1141 gacggaagaa aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta
     1201 tcagcattgg ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta
     1261 ttcaatcgta atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga
     1321 tacgaccttg caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg
     1381 gctgcctggt atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag
     1441 agagcaaggg atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga
     1501 atggaaagaa gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt
     1561 agattacagt agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt
     1621 ttttgttacc ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga
     1681 tcctcaagca cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc
     1741 cttttatcat atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac
     1801 ccgtccagaa acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta
     1861 tcaagcgctc atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat
     1921 tgcagatgaa tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca
     1981 tgatccaaac gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga
     2041 tgatgatggt acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc
     2101 tcgtaaagca atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat
     2161 gatccacagt gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac
     2221 tcaatggttt gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga
     2281 tcaagcagtg gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa
     2341 tgtccatgat tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta
     2401 tcacaaagaa acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg
     2461 ggtacaagat cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac
     2521 aatgggctgg ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt
     2581 agtaaccggt tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga
     2641 atttactggc gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca
     2701 agggcggaag atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa
     2761 gtatggagca gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt
     2821 ccgcttcagc tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc
     2881 ttcacgtttc gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg
     2941 agaaaaatca gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt
     3001 aactgagcta tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat
     3061 ctgggatgat ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga
     3121 tgctgtttca aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg
     3181 tttattgcat ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca
     3241 gggaaattct ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac
     3301 agcttctaaa gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc
     3361 agaagtgaat acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa
     3421 aatcgatcaa tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga
     3481 gttgacgata tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg
     3541 tgcagaaatc ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt
     3601 agaaaaagaa ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa
     3661 tgaacgtttt gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa
     3721 agattattta gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca
     3781 ataagaatag aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga
     3841 acatcgttac aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga
     3901 cataaatttt gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg
     3961 tggatcatgt atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt
     4021 ttctctttgt catactttta tttttcttat gtgttctatt tgttataata aaagagaaat
     4081 gggggaattg ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt
     4141 tggttcacgt cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga
     4201 gagaaaagta aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta
     4261 tttgagaagc ctattagaag aggctgggct gacagtaggt acatttactt caccttatat
     4321 cgaaacgttc aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat
     4381 ccagcttgta aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc
     4441 tggtattact gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa
     4501 agtggacgta gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc
     4561 tgtaccaatg ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga
     4621 tacaattgaa gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt
     4681 aacaggaaat attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa
     4741 tgcaccgctt tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat
     4801 gtggggagaa gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc
     4861 gcttttaggg caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta
     4921 ctgtcaattg gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc
     4981 tcgatggcca ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc
     5041 ccataatacg catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata
     5101 tcaaatcaac attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg
     5161 attgcagcaa gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat
     5221 cgaattaagt gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca
     5281 attcggatta gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg
     5341 ttcactttat ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga
     5401 agtataatgc agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt
     5461 acgaagccac acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt
     5521 taaaattctt aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg
     5581 aatttggcaa aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac
     5641 gtttttcgca aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag
     5701 aagaacatca gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt
     5761 tattgaagaa gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc
     5821 aacgagcaaa accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga
     5881 agaaagaaac attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg
     5941 agatcccggt agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa
     6001 cagctggggt tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct
     6061 cttttcgtat cttattttag ataagataga aaggagatgt ttttttggga aaacgattga
     6121 tcaaagaagt acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag
     6181 ctttatcgga tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg
     6241 tgatgtcgat tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg
     6301 ctactttgca tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca
     6361 aagccttgat cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg
     6421 ttcgtaccag ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag
     6481 aacatttggt ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt
     6541 tcatcggttc gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac
     6601 gttattgtgc agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat
     6661 cgcagcagga tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca
     6721 ctgtactgga ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa
     6781 tgatggaaga gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat
     6841 tgtaattttg tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca
     6901 atgttacaat ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac
     6961 agtaaaatgg ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga
     7021 cgtattcgtt cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca
     7081 agcagtgact ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa
     7141 agcttaattt tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa
     7201 gcgagtaaca aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt
     7261 atgaaaaagt aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga
     7321 acaaacaaaa atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg
     7381 ctgatttcat aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt
     7441 ggatgtcttt ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc
     7501 aatttatatt ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt
     7561 cgctgagctt cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga
     7621 atatctggac cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca
     7681 agaccttctt ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc
     7741 ccgctaccat cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg
     7801 ctagttaacg ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct
     7861 acatcttgtg ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata
     7921 aaatattttg gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg
     7981 gaagtatgga tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa
     8041 ttgatcaaat gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact
     8101 gtatcgtctg gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg
     8161 gccatcgctt ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga
     8221 ttgatttcgt gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga
     8281 ccgttgacga tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc
     8341 acagcggcat ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg
     8401 atacgtcctt cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat
     8461 ttagtaaatg ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct
     8521 tccccgatac gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat
     8581 ttgaagtctc cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca
     8641 tctgggatac tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc
     8701 gtatcttcat tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg
     8761 tttgtgatca acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc
     8821 aagtagggta ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact
     8881 ttgtgtaagt tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa
     8941 tcgtcttccg ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc
     9001 ccatacgtat ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta
     9061 tttttgatgg aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc
     9121 gtactctaga tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc
     9181 ttccacacgt tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc
     9241 ttcccgttta gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt
     9301 gtctccttta tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa
     9361 cgaggggaca agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa
     9421 agagacaagc ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat
     9481 aaaaaatata caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc
     9541 aactagattg aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt
     9601 atgagagaag tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta
     9661 acaaaagatt aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata
     9721 agaaattctt gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac
     9781 ttcctacgat tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg
     9841 tgaagcaaca agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct
     9901 tgttaggtta ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt
     9961 tgttcgaaaa gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat
    10021 tgatcactcg tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac
    10081 gtatcggttt tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa
    10141 gtgtgacact cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag
    10201 cgattgctaa ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca
    10261 acagtatctt gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa
    10321 agtttgaaga aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct
    10381 tattccgttt gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg
    10441 tattgatcat ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt
    10501 tgattgcgtt tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg
    10561 tgttcatgat gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg
    10621 ccaaaccttc gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata
    10681 tcgaatttca aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa
    10741 atgtcagttt tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg
    10801 gaaaatctac gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct
    10861 tgatcgatgg agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt
    10921 ttattccgca aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga
    10981 aagaagatgc tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat
    11041 tcatttctcg aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt
    11101 caggtggaca aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct
    11161 atatttttga tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc
    11221 gtctgaaaaa agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga
    11281 tcatgcatgc agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc
    11341 atcgggagtt gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa
    11401 aggaggaatt agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag
    11461 accgtatcgt gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa
    11521 cgtggctttg ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa
    11581 tggcgaatca atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg
    11641 aatagggtat tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag
    11701 tgccatgcat gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata
    11761 tttcgataaa aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt
    11821 cagcggtgct ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt
    11881 ggctgcagca atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat
    11941 tccaacatcg atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag
    12001 catgcagaat tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag
    12061 tgtattgaaa gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca
    12121 cagcttgaaa tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt
    12181 tcaattaact gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat
    12241 tactggggcg atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag
    12301 tcagccaatg gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac
    12361 gaaacgtgta ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc
    12421 actgccagaa acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc
    12481 gaagaaacca ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt
    12541 ggtcggtccg accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga
    12601 cgtagacaaa ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga
    12661 tgtgcgttcg ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc
    12721 agataatatc cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa
    12781 aacagcaaac gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa
    12841 ttctgaggga gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt
    12901 ggtctccgat cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt
    12961 agaagcgttg attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat
    13021 cgctcaccgt ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca
    13081 gatcattgaa aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact
    13141 gtataacagc caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa
    13201 acttattttt tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg
    13261 acacggagat ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc
    13321 gtttaacgca cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt
    13381 ttcaaatcga acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa
    13441 tagaagaaaa tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa
    13501 atagacatct ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct
    13561 atgatacctt tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat
    13621 ggaacggttt atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt
    13681 gacgatctgg tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag
    13741 aacgaatatc caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc
    13801 ggagaatgtg acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc
    13861 gctgatcggg atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat
    13921 tggtgctgga tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg
    13981 tcgcccagct aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa
    14041 catccagcat tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag
    14101 ataggcagta gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt
    14161 tatttggttt agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa
    14221 gaactgtttt ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata
    14281 tagttgtcac gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct
    14341 aaaattttgt ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca
    14401 gttgcttgcc cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa
    14461 gcaaatcgtt taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata
    14521 cccataacaa ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata
    14581 cctgctgtaa ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct
    14641 tgagcgtcta agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg
    14701 ccgcttaaca tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca
    14761 cctcgtgaag attgttcaat gactgtagga attaaattca taatagagtt cctccttgat
    14821 ttcgtttaga aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt
    14881 ttggtcaaaa aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg
    14941 gtatgataag cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg
    15001 ccttatcgga gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg
    15061 tcacttggaa aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga
    15121 gacgctgaat caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat
    15181 ggaagaatat gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc
    15241 gtatctccaa tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga
    15301 gctatttaag aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat
    15361 tggtggatat gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac
    15421 tgaaatgatc aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt
    15481 cttctcgaaa gatgatgttt ggagctgata ttttgaagca ttgccgttgc acatgagagc
    15541 gtggtaatgc tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat
    15601 gttacaaatc tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc
    15661 atttgcagaa gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa
    15721 agatggttat ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg
    15781 gctgattcga gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag
    15841 caaagaattt ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca
    15901 aaaaaattac cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg
    15961 tatcgaagaa aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata
    16021 ttgcagcttt catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct
    16081 ggacttattg atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat
    16141 agaaggagta catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt
    16201 tccaaaagca attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga
    16261 actcaaaata gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc
    16321 aacgaaaagt aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg
    16381 taaaacagcg ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga
    16441 ttcattgcaa atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat
    16501 gaataatgtt ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgt
    16561 tgattttcag cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc
    16621 tatcatagct ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg
    16681 agcgacagaa gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat
    16741 tggttcccaa gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat
    16801 ccactggaac aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca
    16861 tagtatcacg gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt
    16921 agatacgaag cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc
    16981 agaaggttta gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca
    17041 aggtattgga tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc
    17101 aacagaacaa gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg
    17161 taaccgtttg gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat
    17221 tgagcaaaca atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg
    17281 taggggtaga aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc
    17341 agctgacgaa taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag
    17401 tggatcggca aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg
    17461 cgcatgaagc ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga
    17521 ttaccgatgc tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg
    17581 cgatgcgtgc tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc
    17641 tgctgcctcg tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa
    17701 caagagggcc aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt
    17761 ttgctgttaa gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa
    17821 gaaaaaatag cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa
    17881 ctatcttgaa tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt
    17941 tagatccatt gactaagaga tggcgttttg ctgaaggatt tgagattact gtaacggata
    18001 ccgtcgggtt catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag
    18061 aagaaagtca aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta
    18121 ttttacagga gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga
    18181 tactgactgt ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat
    18241 tcccaaatgt attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa
    18301 tcaaacgtca gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag
    18361 gacagaaatt aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag
    18421 aaacaaacga atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa
    18481 accaataaaa ttttattttt ttaa
//
LOCUS       DBBGRF010000056        18254 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000056 DBBGRF010000000
VERSION     DBBGRF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.056"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(229..906)
                     /gene="phoU"
                     /locus_tag="ACIZD4_002283"
     CDS             complement(229..906)
                     /gene="phoU"
                     /locus_tag="ACIZD4_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGC5991170.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            complement(919..1677)
                     /gene="pstB"
                     /locus_tag="ACIZD4_002284"
     CDS             complement(919..1677)
                     /gene="pstB"
                     /locus_tag="ACIZD4_002284"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGC5991171.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            complement(1693..2499)
                     /gene="pstB"
                     /locus_tag="ACIZD4_002285"
     CDS             complement(1693..2499)
                     /gene="pstB"
                     /locus_tag="ACIZD4_002285"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGC5991172.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDIHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            complement(2514..3398)
                     /gene="pstA"
                     /locus_tag="ACIZD4_002286"
     CDS             complement(2514..3398)
                     /gene="pstA"
                     /locus_tag="ACIZD4_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGC5991173.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVMKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            complement(3398..4318)
                     /gene="pstC"
                     /locus_tag="ACIZD4_002287"
     CDS             complement(3398..4318)
                     /gene="pstC"
                     /locus_tag="ACIZD4_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGC5991174.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            complement(4433..5290)
                     /locus_tag="ACIZD4_002288"
     CDS             complement(4433..5290)
                     /locus_tag="ACIZD4_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGC5991175.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            complement(5627..7075)
                     /gene="cls"
                     /locus_tag="ACIZD4_002289"
     CDS             complement(5627..7075)
                     /gene="cls"
                     /locus_tag="ACIZD4_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGC5991176.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(7227..8111)
                     /gene="ftsX"
                     /locus_tag="ACIZD4_002290"
     CDS             complement(7227..8111)
                     /gene="ftsX"
                     /locus_tag="ACIZD4_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGC5991177.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIRPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            complement(8104..8790)
                     /gene="ftsE"
                     /locus_tag="ACIZD4_002291"
     CDS             complement(8104..8790)
                     /gene="ftsE"
                     /locus_tag="ACIZD4_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGC5991178.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(8895..9996)
                     /gene="prfB"
                     /locus_tag="ACIZD4_002292"
     CDS             complement(join(8895..9923,9925..9996))
                     /gene="prfB"
                     /locus_tag="ACIZD4_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGC5991179.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(10122..12656)
                     /gene="secA"
                     /locus_tag="ACIZD4_002293"
     CDS             complement(10122..12656)
                     /gene="secA"
                     /locus_tag="ACIZD4_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGC5991180.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(12878..13429)
                     /gene="raiA"
                     /locus_tag="ACIZD4_002294"
     CDS             complement(12878..13429)
                     /gene="raiA"
                     /locus_tag="ACIZD4_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGC5991181.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(13557..14276)
                     /locus_tag="ACIZD4_002295"
     CDS             complement(13557..14276)
                     /locus_tag="ACIZD4_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGC5991182.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            complement(14273..15586)
                     /locus_tag="ACIZD4_002296"
     CDS             complement(14273..15586)
                     /locus_tag="ACIZD4_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGC5991183.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            complement(15667..15987)
                     /locus_tag="ACIZD4_002297"
     CDS             complement(15667..15987)
                     /locus_tag="ACIZD4_002297"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC5991184.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            complement(16095..16382)
                     /locus_tag="ACIZD4_002298"
     CDS             complement(16095..16382)
                     /locus_tag="ACIZD4_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991185.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            16509..17153
                     /locus_tag="ACIZD4_002299"
     CDS             16509..17153
                     /locus_tag="ACIZD4_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGC5991186.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(17212..17919)
                     /locus_tag="ACIZD4_002300"
     CDS             complement(17212..17919)
                     /locus_tag="ACIZD4_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5991187.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
BASE COUNT         5095 a         3983 c         3191 g         5985 t
ORIGIN      
        1 ttgcattctt tatcctttct atgaaatgat gaaaagggtt tgtgacatgt tttgtcacaa
       61 accctttccc gaataaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaaa
      121 cgaaaaatat gaggagctat tttttgtttg actgttctta ttacttgatg tagaacagct
      181 ttttcacaac ctcttttcat aaacaaacgg cataatcaca gcttcagttt agaaaatctc
      241 attgtggttc gtatttaact cagtgatttt ccctgtagcc aagtagacga tccattcaca
      301 gatgtttgtc acatagtctc cgatccgttc tagataactg gcaacattca agtagtctgt
      361 tccactgatg actgtctcag gattttcctg catatttttg attgttgcat tatagattcg
      421 attgaaatag tcattgactc tttgatccat attggcgatc gtacgtgcgt ctttttcgtc
      481 tgttttgaca taagcaacta ggacgttgtc caccattttt ttcacataat cggacatatc
      541 ggagatctct ttttcgattt ccggtattct cgtctgccct tttacgcgaa tcgtggattt
      601 agcaacagac accgcatgat cggccatacg ttctaaatcc gagctagctt tcatgaccgt
      661 aatgatcata cgcaaatcag ttgtaactgg ctgttgcaat gcgatcattt caaaactttt
      721 cttctccaag cgtgtttcca tgttattgat atttatatcg ttttcgataa cttcttgggc
      781 taagatttta tcgtgtttga tgtatgcacg aactgacttg tgcacggcgc tgctcaccat
      841 catccccatt tcgtagaact gattatggag attcagcaat tcttcttcaa attgtgtacg
      901 tagcattccg tttcctcctt atccaaatcg acctgaaata taatcttctg tctcttgttt
      961 ttctggattc atgaatatct tcttcgtatc gttgtattcg atcaagtgac catctaaaaa
     1021 gaatgccgtc ttatctgaaa tacgtgaagc ttgagacata ttatgggtca cgatgatcat
     1081 cgtataccgc tctcttaatt ctaacagcat actttcgatt ttcccagtag aaacaggatc
     1141 aagcgcactt gttggttcat ccaataagat gatttccgga ttaactgcca aaacacgtgc
     1201 gatacataca cgctgctgct gcccgccgga taaagataaa gcacttttat gcaatttgtc
     1261 tttcacatca tcccaaacag acgctgcctt caggctttct tcaactactt gatcaaggac
     1321 ttttttatct ttttcccctt ttaatttcaa tccatagatg acattttcat agatagaaaa
     1381 aggaaatggg tttggctgct ggaataccat gccgatttct tttcttagtt caacaacatc
     1441 tgtttttgga ccatagatgt ctttgtcttt atataaaaca cttccggtga tcgttacatt
     1501 cggaatcagg tcattcatcc ggttcaaaga acgcagataa gtggattttc cgcaaccaga
     1561 aggaccgatc atcgcagtga tttccccttg attgaaactt agatcgatcc cttttagtgc
     1621 ttctttcttt ccataataca gatgaagatc tttagatgaa ataatttctt ttgtcatgtt
     1681 gaggcctccg tcttaaccaa aatgaccgga cacataatct tcggttgcct gaatttttgg
     1741 tctggtaaat atcttgttag ttttgtcata ttccattact tttcctagat agaaaaaggc
     1801 agtatagtcg ctgatacgag ctgcttgttg catgttatgc gtcacgatga tgatcgtata
     1861 gtcttctttc aagtttacaa gtgtttcttc aaccgttcct gtcgaaatag ggtccaaagc
     1921 acttgccggc tcgtctagca gcaagatatc aggtttcatc gcgatcgcac gagcaatgca
     1981 taaacgttgc tgttgcccgc cagataaagc caaggcactt ttgtccaagc tgtcttttac
     2041 ttggtcccac aaggcagctt gtttcaagct tgtttcaacg atttcatcta atttcttttt
     2101 gtttttttcg ccgtgctgtt tcaaagcaaa tgtaatattg tcataaatcg acttgctgaa
     2161 cggattagga cgttgaaaaa ccatgccaat ccgtttgcgc atctcataaa catccacttg
     2221 aggcgcatta atatctacgc cttgatacat gattttccca gtgattttcg tattagcgat
     2281 cccatcattc attcgattca acgaacgaag atacgtagat tttccgcagc cggaaggacc
     2341 aatcagtgca gtgatcttat ttttttcaaa ttccagatcc actcctttga ttgcttcatt
     2401 gtcgccatac cagacatgta tatcatccgt atatagtgct acttctttct cttttggcat
     2461 ggtgatgaca tttgtttcat tccagttata ttttttcatt ttgcttcttc tccttaggct
     2521 gaagtcattt ttcggtataa tcgtttgcca atcgcacgag cgccgaagtt gaacagtaaa
     2581 acagcaatga tcaacacggc agaagcgcca gccgaaacag aaacaccatc aggcatcgtg
     2641 ccttctgtat tgatcttcca aatatggaca gctaatgttt cagcttgacg gaaaatgctg
     2701 atcgggcttg aaacacttaa tggattccag ttcgtaaaat ctaacgcagg tgcactttgt
     2761 ccagccgtat agatcaatgc agctgcttca ccaaaaattc ttccagaact taggatcaca
     2821 ccagtcaaaa tccctggtgt cgcttctgga accaccactt tcatcactgt ttcccagcgt
     2881 gacaaaccta aggccaatcc tgcttctcgt tgtgtgtaat ggaccgcttg taaagactcc
     2941 tcaactgttc tagtcaaaag aggcaagttg aatacagtca aagccaatgc accagaaata
     3001 atcgagaaac catactggaa ttgaataacg aaaaccaaga aaccgaataa accgacaacg
     3061 acagaaggca acgagctcaa gatttcaatc gacgtgcgaa tcacatctgt tagccagttt
     3121 tttccagcat attctgaaag atagataccc gcacctaaag aaataggaaa actgatgatc
     3181 atcgtgatca aaagcaaata aatcgagtta aatagctgga tcccgattcc accaccttct
     3241 tggtaggctt tggaaggttc ggtcaagaag gaccatgaaa tgtgcggtat tccccgaact
     3301 aagatataaa gtagtaaagc tgctaaaatc aatacgatga tccccgaaac tatatataaa
     3361 acacctgtag caattttatc tgagcgtttt gcgttcatta tttcagctct cctttcttcc
     3421 caatcatacg gatcacgata ttaaagaata atgacatcaa tagcaagatc agcgctaatg
     3481 accataacac attattttca actgttccca tgattgtatt tccgattccc attgttaaga
     3541 tggacgtcaa tgtagaagca ggagtagtaa gtcctgttgg catcaatgct gcattaccga
     3601 tgaccatttg gatagctaag gcttcaccaa acgcacgagc cataccaaaa acgactgctg
     3661 ttaaaatccc gggcacggct gctcgtagca cgactttgta gattgtttgc catcttgtgg
     3721 caccaagcgc taatgaagct tcccgatagt gccgtggtac tgcctttaat gcatcaacag
     3781 tcatcgttgt gacagtcggc aagatcataa cgaacaacac aaatgtacca gctaagatac
     3841 caaaccctgt cccgccaaaa atacttctga caaaaggcac gataactgat aaaccgataa
     3901 aaccataaac gacagaagga atacctacaa gcagctcgat gaccggctgt aagatcttcg
     3961 ttccgttttt aggagagatc tccgtcatga atactgctgc accaatggca aatggcgtgg
     4021 caacgatagc agataaaaag gtcacaataa acgaacctgt gatcataggc aatgccccta
     4081 ccattggttt cccatttgct ccgatttggc ttggattcca atctgtacca aacagaaaat
     4141 caaatacatt gatcttatca gtaaaaaagg tggccaatcc tttactagct acaaaataaa
     4201 aaatagataa tacaaccaac acgatcagcg cgatacataa aaaactgatg aattttccac
     4261 gctgttccat ttttgaacgt tttgattttg ttaataatac ttttttcaca tcttccacag
     4321 atgactcccc cttaatcagg tttaacatac tcactcagtg tacaaattga acatcaattt
     4381 ggttttaata acatgtaaaa gtttagctaa gtttgtaaat tttgtgtaaa gattactctt
     4441 taacgatatt tccttgccaa tcacgttcga ctttcatatg agaaacaggg atataaccta
     4501 gttctccaac gatgttatct tgtacttcat cagataagat atagtctaaa aattcttttg
     4561 tcagtttttt tggatgatct cttgtgtaca tatgctcata tgcccaaatc gtccatttgt
     4621 tcgttgtcac attttcatct gtcggttcta caccgttaac attcaacgta tctacatcat
     4681 cggaaacata agaaaaagca acatagctga ttgcaccggg tgtgtcggca acgatctggc
     4741 gcaccattcc gcttgaatct tgttcttgtg cctgaacagc tgtttctccg tccaataccc
     4801 atttttcaaa cgtgctacgg gttccgcttc ctgaagcgcg gttcaatata actactggct
     4861 gatcttttcc accgacttca ctccagtttt tgatctcgcc tgtaaatagt tttttcaggt
     4921 tttccatact gatgtctttt acgccaatat ccttgttcac aataggagtg atcccaacaa
     4981 ctgctactcg atgatcgact aatgctgagg catcgatccc cgatttttct tccgcaaaca
     5041 aatcagagtt tccgatgtcg actgctcctg actgtacttg agacaaacca gttccgcttc
     5101 cgcccccttg tacattgatg aattttccag gattttctgt ctggtaagtt tcagcaactg
     5161 tttctactaa aggctgtaaa gcagaagagc caacagccgt aatggattct cctcgatcaa
     5221 tccactttga acagcctgat aaaagaatgg ctaatcctat tattggtaag aataatttaa
     5281 gttttttcat tagaaatctc ctttaatcct aaagtatgtt tattttatca ttttcattac
     5341 ttgatgaaaa cgaatcaaaa tcattaaata acaaaataaa ttctcataat tgtaaaaaaa
     5401 actatctcat taaaagtttc tatgctatac tggctttgaa atgtgtctct tttaatagca
     5461 tatattagct tatttcttgc tttccccaaa aaacaagaga taccccaaag ttaatttcgc
     5521 tcatgcgaga cgctttctcc atttctgacg tactctcaga aatggccccg ttagaaaagg
     5581 acacgagatc tccatctgtt gatggttctc atgtcctttt tatgttttaa aggagcggcg
     5641 aaatcaatct tgctaatcct tctttcatct tgatgattat tcctcggttt tcatacattt
     5701 cttttgtgag atgcgtagaa attttcgagt cttcaaaaaa agcttttctt acacgtgaag
     5761 ccattcgttc atcataaacc agtgtattga cctcaaagtc caagcgaaat gaacgaacat
     5821 cgatatttgc tgagccaact gaaacaatgc caccatcgat aatcatcgtc tttgcatgaa
     5881 taaatccatt ctcatatgtt tcgatccttg ctccatactc gatcagctct gcagcgaaag
     5941 aatacgttgc ccagtaaacg agaagatgat ctggtttgtt aggtatttgg atatgaactt
     6001 ttacgcctga aagaagagcc aacttcagtg cttcatgaat cgatccatcc ggtatgtaat
     6061 aaggcgtttg gatcaatatc tcccgtttgg ctaacgaaat cattttcaaa taagtcattt
     6121 tgatttgttc atgttcggta tctggtccgc ttgtcacgat ttgaacagct atatcaccag
     6181 tagtgtgaat ggacgggaaa aatttgggag aatagcctac ttcttttgta tgctgagaat
     6241 tccagtccat caaaaaacgg ttttgcaagg tatacaccgc ttctccgtaa atacgcaaat
     6301 gattgtctcg ccaataacca aatttcttta ccaatcctag atattcattt ccaacattga
     6361 acccacctgt atatccgatt ttcccatcaa taactacgat tttacgatga ttgcgataat
     6421 tgatccgagg attaatatac ggaacaaata gaggaaagaa aaatgcgact tctccgcctg
     6481 cttttttcaa attctgaaaa aagctggaag aaacttgtgt ggaaccccat gcatcaagaa
     6541 ggactctgac ttttacccct cgtcttgccg cctctgtcaa tgcatctcga acttcttcac
     6601 ctaatgcatc actgcgataa atataatact ggaagtggat atggtcttct gcctgcttga
     6661 tatcttcaat cagcgcatcg aatttttcac gaccatctgt aaataaagtg atttcatttt
     6721 tagtcgtata gagcgtactt tcaaataccg tgagcatata gatcaattgt ttcacatcta
     6781 cttgtccagt aggcggatga ggataaagcc ctcgcatcaa tgcctgtttg tcttcttcaa
     6841 tttccaggtt cttaccgatt ttcccttgga tcttcaaatc aaagattttc tctttggaaa
     6901 tccctcttcc taaaaaaata tataaaataa atcctacaac tggaatgaac atcaaaacga
     6961 gcagccatgc ccatgtttga gcagtttcct ttctttctcg aaaaacgatg ataaaggaaa
     7021 gcaaaatatt cataatcaaa aggatcgtaa aaaaattgtc aacgataatt ttcacggctt
     7081 cacctcttct tctaccaact taagaatacc caagttgttt tttaaagtaa agggaaaaaa
     7141 gccgcttcct tctattctcc tagccaataa aaaaagaaag ctggaacgaa actgtccaac
     7201 tttctcattt tatttatatt gtggtattag aatttcaaaa aacgtctcat agaaatgatc
     7261 gagccaagtg aaccaatgat cacaccaatg ccgaccatta aaagattgat tttccaaacg
     7321 atattttgtg gacgaatcaa tgaataatgg gaacgtaata atgatggatt gatcaattgg
     7381 aaaaaccatg cataaccaaa tgtgatgatc aaaatcggaa gaatcgcacc gatcagaccg
     7441 atccagccac cttcaaggaa aaacggccag cgaatatatc cattttttgc accgactaaa
     7501 cgcatgattt gaatttcacg ctgtctagac aaaatcgtga tccgaatcgt gttcgaaatg
     7561 agaaacatcg ctacgaacag cagcaatgcc gctgcaacta atccccatgt ccgaactgca
     7621 ccagcgattt ggaaaatccg atctgaggaa gctccaccgt aatcagaacg agaaacattc
     7681 ttcaaatctg ctgcttcttc tgctacttgt tttgtataag aaggatcagt agcacttact
     7741 acatacacat catataacgg gttattgtca ccttcaaaca atttccagga atcacccatt
     7801 tcgttttgga tttttttcaa ttcctgttct ttgcttgaaa attcaacttt tttaacatga
     7861 tctaagtcat tcaattcttt ttctagcttt ttcatctctt cgtcttttgt accgatatct
     7921 acgaatacag atacatcaac gtttccttct atatcctgag ctaatttagt tgcattcatg
     7981 ataactgcca tgaatacacc gactaaagtc aacgtgatcg ttaccgcact gactgaagca
     8041 actgtcatcc agccgttacg tttcaaactc ttgatacttt ctaataaatg gcggaaaaag
     8101 gttctaatca tcgtatccat attccccttc cgcttgatct cgaataatgc ggccgttttc
     8161 gatagcaatt actcggtgcc gaatcgtatt tacgatcgta ctgttatgtg tagccatcac
     8221 gacagtagtt ccttgggcat tgatccgatc taataatttc atgatttccc atgagttttc
     8281 tggatccaga tttcctgtcg gttcatccgc gataagtact ttaggcgtat tcacgattgc
     8341 ccgagcaata gagacacgtt gctgttcccc accggataat tcgctaggaa agactcgaac
     8401 tttgtgtttc aaaccaacaa ggtccagcac ttccattact cgttttttga tatctcgagg
     8461 ttttctgccg ataacttgca tagcgtacgc aacattttca tatactgttt ttcttggtaa
     8521 taatttatag tcttggaaca ccacgccgat ttctctgcgt agataaggaa cttcgcggtt
     8581 tttgattgct attagatcat gacctgcgac gttcaaagtt ccttttgaag ctttttcttc
     8641 tcgatacatc aatttgatga atgtagattt accggctcca gacggaccaa ccacatagac
     8701 aaactctcct tgttcgatga caatcgagag attgcggata gcggtcgtac catttgagta
     8761 cttcttcatt acatccttca tttcaatcat ggcgttctct ccatatcttt ttcagtcttt
     8821 agctattata gcatggcaat gtttcaacat gcttgcaaaa tcttacaatt ttatttcaat
     8881 ttaacaatga gttcttattg tagatgcatt tttaaatagc cgtcaataaa taaatcaagg
     8941 tcaccgtcca taactgcttg gacatttcct gtctctacgt ttgtccgatg gtcttttacc
     9001 atagaatagg gatggaaaac ataagaacgg atctgtgaac cccagccgat ttctttttgt
     9061 tctcctcgaa gtgcagctgc ttcttgttct ttcttttcca cttctaattg ataaagctta
     9121 gcttttaaca tccccatcgc ttgctcacgg tttttcaatt gtgagcgttg tgcctgacta
     9181 gctactactg ttcctgtagg caagtgagtg atccgtacag cagattctgt tttattgatg
     9241 tgctgaccac ctgcaccact tgctcggtac gtatcgattt tcaaatcatc tggattgatt
     9301 tctatatcga tcgtttcatc aagctctggc atcacatcta ccgaacaaaa agaagtatga
     9361 cgtcgtttcg ctgagtcaaa aggcgaaatc cgtacaaggc gatgaacacc tttttctgat
     9421 tttagataac caaaagcgtt atgtccttta atcagcaggg tcacactctt gatccctgct
     9481 tcatcacctg cttgataatc tagtgtttct acttgatagc catgctgctc tgcccaacgt
     9541 gtatacatac gtaaaagcat gctgccccag tcttgggact ccgttccgcc agcccctgga
     9601 tgcaattcga cgatcgcatt gtttcgatca taaggtccgt ctaacagcat agataattca
     9661 tacgtcttca ttttttcatc taatgcattg atacgtgttt ctgcttcttc ttgcattgct
     9721 gcatcaggtt cttcttgcag catctccacc atcaattcga tttcttctag ttcttcggca
     9781 agagaatgga attggtcata ggtttcttta ttagcgttat tttcgctgat cactttttgt
     9841 gcggcttcgc tgtcatccca aaaaccaggt tcagccattt ttgcttctgc ttccgcgatg
     9901 tcttcttcca gctgatctaa gtcaaagaga cctcctgaaa cttgtgacct tttcctgcat
     9961 ttctgtcagg agatttcgaa tttcggatat ttccatgttt tttccttctt tcactatact
    10021 tttttcatta tatctagtct aacagaatca gcaaataaca gaaagaaggt gagacgaatt
    10081 cttaaaaaaa gaatttgtct caccaatcct gctgtcagaa attagtttgc attttttcca
    10141 tgacagttct tatatttttt cccgcttcca caaggacaag gatcatttct tccgaccttg
    10201 ttcacatgga ttggctgttt tttcgcgcta gtattactat tttctttggc atctccgtct
    10261 tctgagtgag aagctgttcc ttgagaaacc tgttcacgct gtacgttttg acggatctca
    10321 gctttcataa agattcgagt gacttcatac tcgatggcgc ctaccatatc ttcaaacatc
    10381 ttatagcctt ctgtttgata ttcgactaat ggattgttct gtccataagc acgtaagccg
    10441 attgactgac gtaattgatc cattgcatca atatggtctg tccatttaga gtccacaaca
    10501 cgcaagatca cgactttttc aaattccaac agttgctctg gaccatttag ttgagccgct
    10561 ttggtattaa atacttcttg tgctcgttcg tttagatact ctttgatctc ctgagatgtt
    10621 tttccttcga tatctgcaag agtaatacta tcttcatgga caagagtact gccggcaaaa
    10681 tcgatgatac tttccaaatt ccaattttct ttctctaatt gtgtatgcgc atctactaca
    10741 cgactgattg tccgtttgac catgttcatt agtggcttgg ataagctttt ttcttccatg
    10801 attacttctt gtcgctgttt atagattact tcacgttgtt cacgcatcac atcatcgtat
    10861 tgtaagacgt ttttacgtgt gtcatagtta tttccttcta cacgtttttg tgcagattct
    10921 acttgtttcg tcagcatctt gctttggata acagcatctt cctcaccgat cttcatccga
    10981 tctaagaaag ctttgattcg ttctgaaccg aatcgtttca tcaaatcatc ttccaatgac
    11041 aagtagaatt gtgacatacc agggtctcct tgacgtcctg cacgtcctcg aagctggtta
    11101 tcgatacgac gagattcatg tcgttctgtc ccgataactg ctagaccacc aagttctctt
    11161 accccaagtc ctaacttgat atctgttccc cgaccagcca tgttggtagc aatcgtcaca
    11221 gcaccttttt gaccagcatt catgatgatc tctgcttctt taaagtgatt tttcgcattc
    11281 agcacttcat gaggaatacg ttcttgattc agcatatctg ataataactc agatgtttca
    11341 accgcaacag ttccgactaa cacaggttga cctttgcggt agcgatcttt gatatcttgc
    11401 acgacagcgt ggaacttgct ttgtaatgtt gggtaaagta aatctggacg atcatcacgg
    11461 ataaccggac gatttgtcgg aatctggtat acttggatgt tataaatttc tctgaattct
    11521 tcttcttctg ttttagctgt accagtcatt cccgcaagtt tcttgtacat acggaaatag
    11581 ttctggaaag tgatcgtcgc catggttttc gtttcgtctt cgatctctac gccttcttta
    11641 gcttcgattg cttggtgaag tccatctgaa taacggcgtc catccatgat ccgaccagtg
    11701 aactggtcaa caatcagtac ttttccgtct tggacaacat aatcgatatc taaaagcatg
    11761 atatagttgg ctctcaatgc ttgatccaag tgatgggtca atgcagtatt ttcaatgtcg
    11821 tataagttat ccaaaccgaa tgtttcttct gctttttcga tccctgcttc ggttaaactg
    11881 attgtttttg attgtacatc gattttataa tcttcttctt ctttcaaacg tttcacgaag
    11941 ttgtctgctc ttgtatataa agctgtggat ttttctgctt gccctgaaat gatcagcggc
    12001 gttctcgctt catcaatcaa gattgagtca acttcatcga caatggcata attcagcgga
    12061 cgttgtacca tttgatggcg gtaaacgacc atattgtctc tcaagtagtc aaatcctaat
    12121 tcattattcg tactataagt gatatcacaa ttataagcct cgcgtttttc atccgaagat
    12181 tttgagttga tattcaaccc cactgttaat cctaagaaat tataaagttc gcccatttcc
    12241 gtcgagtcac gggttgctaa atattcattg acggtaacta cgtgtacccc ttcgccagtc
    12301 agagcattta gatatactgg catcgttgcg gtcaaggttt taccttcacc agtacgcatt
    12361 tcagggatat ttccatcgtg aagcacgatt ccacccatca attgtacgtg gtatggatat
    12421 aaccccaata cacgttttgc tgcttctcgg acgactgcaa aagcttccgg aagtaattga
    12481 tctaatgttt ctcctttttg gtatctgccc ttgaattcag cagtttttgc ctgtaattgt
    12541 tcatcagtta atgctgccat ttggtcagcg tatgcttcaa ctttttttgc aatgctatct
    12601 aaacgtttta gttctttctt atcgttttcg ataagtgaac gaatcaaatt ggccatgcgt
    12661 tgtgtaatct ccttttcctt ctgtgtatta tccagactat gtagacttta cttttcattt
    12721 tatcattagt tatagataat tgaaatatct taagcgtatt aaagtaagaa cttcataatt
    12781 tattcatatt tcatctaaaa gaggaggaaa ctcaaaaaaa cttgcggcag ctgtcagtag
    12841 ctgctgcaag ttttcgttgt tatttaagta aggctgatca gtctgtttca atcagtccgt
    12901 attttccatc tttacggcgg taaacgatac ttgtaccatt tgtttctgca tcttcaaaaa
    12961 taaagaagtt atgtcccagc atgttcattt gtaagactgc ttcttcacta tccattggtt
    13021 tcaatgaaag gcgtttcgta cgtacgatat ctaattcaga atcattttcg ttttcgtcct
    13081 cttcattgaa taaagcagca gcatctgcag tattcatgcc cgtttcacgg gatttacgat
    13141 taatttttgt tttgaatttg cggatttggc gttccaattt atcaacaacc aaatcgatac
    13201 ttgcgtataa atctggagaa gtttcttcgg cacgtaatac aagataaggt aatgggatcg
    13261 ttacttccac ttttgctgtt ttttctgtat aaacttttaa gttcacatgc gccgttgcat
    13321 cgggtgcgtc actgaaatag cgttctagtt tgcctacttt tttctcaacg tagtcgcgaa
    13381 tcgcttcagt tacttcgata ttttcgccgc gtacattata tctaaacata aaaattaccc
    13441 ctttcgtcta ccacaatcaa gaaggagaag gaccactctt tccctcttct taattctatt
    13501 atatcgaact ctaggttatt tgcaaattaa atcgctatca aatttccaca tctaattcat
    13561 ctcgccaaag aaatggttcg gatgattttc ggctgtgcga cctgcaaaca atctgctgcg
    13621 tggaaaagag tctgtcctgt tgtatagaca tcatcaataa tcaatatttt tttattttgt
    13681 atcttagaaa aggtgactgc aagttcaaaa ggttgaggca tctccaatct ttcctttcgc
    13741 gtgttttttg cttgagccag cagatgcttc tctcttttga gtagcatctg aaaaggaatt
    13801 cttgctgctt tcaacatctc gcttacttga ttgaatcctc tttctgttcg ccttttttca
    13861 gataaaggta ttggacaata gatgtatgtc gggtattctt tttttatctg cgtccattta
    13921 tatgcaaagg tgcctgctag tcggatatct cccataaact tgtattgatt gagccaggcc
    13981 ttcatatttt catcgtacac aaaaaaggca cggtgctgaa aatcataggt cggatatttc
    14041 ttcttccatt cttgacagtc actgcagtaa acgggaatag actttacttt ctttttcgta
    14101 ctctctagat tgaaatggat tggtttttga cagccagaac agcctcttgt ttccaataaa
    14161 tgaaattgtg cgcgacaaac tgaacaagtc tgaggtaatc tgtatttcga aacaccaata
    14221 atctcgctga atgttaaatt ttggaagata tctttactgc agcaactgca cctcacagca
    14281 tcttcttccc ttcttcattc atttctttga tttcctgaca agcttttcga atagctgcag
    14341 ttttttcttc atagaaaaag tatacttgac tgttcgtata aggcccttta cgatcggctc
    14401 ttcctgcgat ttgtaccaaa gaagatttag taaaaaccgg atgatccgct cctaaaacga
    14461 taacggatat tctttcaaat gtgactccac gttcaaggat catcgtggtt aacagtatat
    14521 catattttgc ttctcgcatt ttctggactt tttccgcccg ctgattgtct cttgaagaaa
    14581 catctgtgat ctcatatctc ggaagagcct cttgaagtgt ggctttcaaa cgatgcatca
    14641 tcgtgatact tggacaaaat aaaaggatat ggttttcttt aattaattga tgaatgatcc
    14701 gcaccaaaga ttttatcttc ttcttgttct tgcatttttg tcgccaatta ttcatgaaaa
    14761 ccaagacggg ttcaggaagc aaacgccgat gaaagcgtaa agcaagtttg tggatgtcaa
    14821 acgtctgctt gatttccttt agtaactttt tatcaggtgt ggcacttaag tagatgaatc
    14881 gtccgtctgg tttaatcgct gtttgcacag catgagctaa tcctgcatcc ccgttataag
    14941 gaaacgcatc gatctcatcg atcactatta aatcaaagga ccgataaaaa cggtatagct
    15001 gatgaatcgt acagataaca aaagaagtaa aggtataagc cgttgctgta ttcccatgga
    15061 gcaacgtgat tttttcttct ggaaaaacat aacgatagcg taaaaacaat tcattacaaa
    15121 catcgactcg cggtgtacaa atcgctactc ttcctccagc ttttaaagtt tccactaaaa
    15181 taggataaag catctctgtt ttccctgcac ctgttacagc ccaaataaga tgatgtcttt
    15241 tttctgaatg gcaaagtatt ctctttgaga tttccgtttg tttttcagta agctgtcctg
    15301 tccaaaaaaa gacgacttct cgaggttttg cttcaggctg atcaaacaaa tataaatctt
    15361 gttgagtgtc gcatcgccct aaatatagac aatgtgtaca aaaataaccg taatctgcaa
    15421 gctgtccatc aatgacggac gtcctcattc cacagcgatg acaaagaatc cagttgccca
    15481 aacgttccac tgctgcgatc ttctcataat ttggtaaatt tacctcctca cagtctattg
    15541 cttcaatatc tctcgtcaga agccttctac cccaaaaatg attcatattc ttcgccctaa
    15601 aaaaatatac gaaaaaacaa gcgatctatt ttttggatcg cttgttcgat agttatactg
    15661 ttctatttat tcacctatga gcgtgattgc ttgatctaac actttttcgc cattcatcat
    15721 accataatca gccatattga tgacatctaa aggaatgcct tttggttcca gacgtttctc
    15781 aaaatcagct ttcataaagc gaacttgtgg gcctaataac aacacatcca cgtctttatt
    15841 tgcaaggttg ttatctgcgt cagaagcgga cacagcgaaa atatccgagt cgattccttt
    15901 tgcttcagca gctttttgca tttttgttac tagtaaactt gtgctcatac cagccgaaca
    15961 tacaagcatg attgtttttt tagccatact tttctctcct ttttaaaaca aactatgcaa
    16021 acgttttctt cgcgtctgtt actctattat ataaaaagaa agaaatttgt caacgttttc
    16081 taaacgcggt ttatttaatc aaatagccaa ctagatttca ctaatttatt gaacacgaca
    16141 tattctttgt ccaaattgat gacaactact tcatagcctg catttatcca gccataggca
    16201 cctttttcag ggtgtttata atcatttgcc caccaatctg tactttccct tgctgttttg
    16261 ggaagtccgt tactgggaaa cagcagttcg tcaaattggg taaaggtcaa cgttacttga
    16321 gagccgccat tgttcttcaa ataatgcgta attgcatcgt actttttcat tcgttcctgc
    16381 atccccagat ccacctgcct ttgtctttat tatcgcatac tacagcaatt gcgcaaccgt
    16441 tacagtgttg aaacaaccta gaactttatt tatactgaat aaagaaaatg aaaaaaagag
    16501 gtgacaagat gatcgagcgc tatcgtacaa taaaagaaaa tggacaaagt gagattgaga
    16561 tcaaaaaatc acgctttatc tgttctctta gacgaataga atcagaggac caagcaaaaa
    16621 gtttcattca agaaataaaa aaagaacatt ggaaagcgaa ccataactgc agcgccttca
    16681 tcattggaga aaaaaatgaa atccagcgaa gcagcgatga tggagaacca agtggaacgg
    16741 cgggcgtacc gatgttggaa gtcctcaaaa aaaatcaact gatcaatgta gctgcagtag
    16801 tcactcgata ttttggagga acgaaactcg gcacaggcgg attaatacga gcatacactc
    16861 atgcggtctc tcaagcattg tctgacattg gaatcgtaga aggtaccttg caacaggaga
    16921 tctctgtgat gatcacgtat ccgcaactag gaaaattaca gaattatctt gaactccaac
    16981 atttttttat aaaagaaatc caatatactg atcaagttag cgtcatctgt gctgtagatg
    17041 aaaaaagtgc tgaccacttt aaagaatcca tcattgagct gctgaacgga caagtccaat
    17101 ttgaagaggg ttctgtttct tatcacgagc aactgataac tgatcatata taaaaacagg
    17161 tgattctgat tctcttttat ttctaataag gaatcaggga tcacctgttt tttatttttc
    17221 caaataaaac tcaaaacgat ttcctacgta ttgcgtacgc acatactcaa acggcgtacc
    17281 gtcttcaaaa taagaaatct ggcgcaaacg aagaactgca tctcctcgtt ttacctctaa
    17341 atagtcagca attttctcag aagccaacac agcagtaatc gtttgattcg ctggaccgat
    17401 ctttttcccg cctttttctt ctagcgtgcg atacaacgat tcagtaatct ctgctttgct
    17461 gtagccatcg atcagctttt gtggaacact ggcaacttca aaacaaatag ggacatcatc
    17521 tgcgaaacga atacgttcca ttcgcaagat cgtgtcatct ttactcaagt ttagtttttc
    17581 catttcactt gagcttggcg aagtcaagaa ataagagatt gtccgactag acggtactcg
    17641 attttgtgat tccataattt ctgtaaaact tgttgcacca gacatttttt cttgtacttt
    17701 ttctcgcgca acatacgtac ccgaaccgat ctttctttct aagattcctt catctgccaa
    17761 gttttgaatt gcttgtctca acgtcatacg gctgacattg aatttcactg ctaattctct
    17821 ttctgaagga agacggtctc cgactttcca tataccctgt tcgatttcat tttttaattg
    17881 gtcatgaatc tgtatatata caggtaattg attcgacata acgtacaccc gtcctttcgt
    17941 ttcttctatt ataactggta tatacctgat tcacaactga aaaagataaa ggtttctatc
    18001 catcaacaga ggatttagac acacatcgtt ctccctactc ctattgtcag aaacaatttt
    18061 ttagatatgt tcaacctaga aaataacaaa agaccctaaa atcgatgaaa atgccgactt
    18121 atggatcttt tgttattatt agcggttttt agccatccat ttttttgtat gattcgttgg
    18181 gcgttttgat tttacctgga ccgcttttcc gccttttttc ggaatattca cttcaatatt
    18241 gtatttttct gatt
//
LOCUS       DBBGRF010000057        17533 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000057 DBBGRF010000000
VERSION     DBBGRF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.057"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            282..521
                     /locus_tag="ACIZD4_002301"
     CDS             282..521
                     /locus_tag="ACIZD4_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991188.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="ACIZD4_002302"
     CDS             complement(883..1143)
                     /locus_tag="ACIZD4_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991189.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1328..1825)
                     /locus_tag="ACIZD4_002303"
     CDS             complement(1328..1825)
                     /locus_tag="ACIZD4_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGC5991190.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1955..2665)
                     /gene="budA"
                     /locus_tag="ACIZD4_002304"
     CDS             complement(1955..2665)
                     /gene="budA"
                     /locus_tag="ACIZD4_002304"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGC5991191.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="ACIZD4_002305"
     CDS             complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="ACIZD4_002305"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HGC5991192.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4547..5209)
                     /locus_tag="ACIZD4_002306"
     CDS             complement(4547..5209)
                     /locus_tag="ACIZD4_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGC5991193.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5219..6034)
                     /locus_tag="ACIZD4_002307"
     CDS             complement(5219..6034)
                     /locus_tag="ACIZD4_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGC5991194.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6296..6739)
                     /locus_tag="ACIZD4_002308"
     CDS             complement(6296..6739)
                     /locus_tag="ACIZD4_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HGC5991195.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6873..7211)
                     /locus_tag="ACIZD4_002309"
     CDS             complement(6873..7211)
                     /locus_tag="ACIZD4_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC5991196.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7199..7576)
                     /locus_tag="ACIZD4_002310"
     CDS             complement(7199..7576)
                     /locus_tag="ACIZD4_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGC5991197.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7800..8993
                     /locus_tag="ACIZD4_002311"
     CDS             7800..8993
                     /locus_tag="ACIZD4_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5991198.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9159..9581)
                     /locus_tag="ACIZD4_002312"
     CDS             complement(9159..9581)
                     /locus_tag="ACIZD4_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991199.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            9976..10170
                     /locus_tag="ACIZD4_002313"
     CDS             9976..10170
                     /locus_tag="ACIZD4_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991200.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            10167..10661
                     /locus_tag="ACIZD4_002314"
     CDS             10167..10661
                     /locus_tag="ACIZD4_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991201.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(10823..11995)
                     /locus_tag="ACIZD4_002315"
     CDS             complement(10823..11995)
                     /locus_tag="ACIZD4_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HGC5991202.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12201..13016)
                     /locus_tag="ACIZD4_002316"
     CDS             complement(12201..13016)
                     /locus_tag="ACIZD4_002316"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HGC5991203.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(13166..13612)
                     /locus_tag="ACIZD4_002317"
     CDS             complement(13166..13612)
                     /locus_tag="ACIZD4_002317"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HGC5991204.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(13609..14124)
                     /locus_tag="ACIZD4_002318"
     CDS             complement(13609..14124)
                     /locus_tag="ACIZD4_002318"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HGC5991205.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            complement(14197..15111)
                     /locus_tag="ACIZD4_002319"
                     /pseudo
     CDS             complement(14197..15111)
                     /locus_tag="ACIZD4_002319"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            complement(15108..17435)
                     /locus_tag="ACIZD4_002320"
     CDS             complement(15108..17435)
                     /locus_tag="ACIZD4_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HGC5991206.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5066 a         3479 c         3052 g         5936 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctctttttat tcttgatttc tcttcttttt tgtttcaata
     1321 gacgatttta gttattaata aatgaaaaag catttatatt aaaatttgct aataaaagat
     1381 ctacatattt ttctagaaat gcttgatcga tttcatcata ccctttcgtt actccgcaat
     1441 cgatatctaa aacaccgatt aaattacctt cttttaccat tggcactacg atttctgatt
     1501 gtgcggctga atcgcaggaa atgtaatttg catgggtttt gacatcatca acgatcaatg
     1561 tttcttgttt ttcagctgat tctccacaaa ctccttttcc catcttgata cgtgtgcaag
     1621 aaactcgccc ttggaacggt cctaaaatca attcattacc atcgaataaa taatatcctg
     1681 caaagacagt ctcaggcaaa gtctcattca acaatgcaga tgaatttgct aaatttgcta
     1741 accagttatc ttctgcttct aataatcctt gttgctgtaa taataaaatt tcgtatgcat
     1801 cttttttctg tttttctgtc cacatgataa aaaccgctcc tttttgatct atggagaaga
     1861 ttatagctca gtttttttgt aaacgctagg tttcctcctc aaaaaaacga gatacgtcag
     1921 gttaatcacc ttgaacgcat ctcgctgtct ttttctattc tgcttgttgg atttctgctg
     1981 ctaaatcagc ataatcaatc gtttcgtgaa caaaagtcgg atcatcaact ggaaaatgct
     2041 gtacaaggga cgagatgcgg ctaatctcaa cttttccttc agccacttca aaatccatta
     2101 catgtccgcc aaatgtatgt gtatcatcga taaaatgcaa gtgaaatccc gctgcagcaa
     2161 ctccttggaa taattcaggc gtaaagaacc cgactaatgt tccttggaca ttgctttgtt
     2221 ggaattctgg ttgagactct gaaatttttg ctagtcttct gtaaggtttt tcttgcttcg
     2281 gcatgatacg gatgtgcata tttttgaata atccagttat cttcactgcc aaaaataggt
     2341 tttccccggc ttctcttact aatatgtctt ttttcaattg ttctccatct gcagtttttg
     2401 agacagaaaa actagtatct ggcgtaaaat ctgtaattgc tgcatagggg gtaagttcac
     2461 ttccatctaa ttgggcaact gagccatctg atcttccttg ataagctacg ccatctaaaa
     2521 agatgacttc accatcaagc ccatgcaatg ttcccaatcc cagagttcct ttttctaata
     2581 tatgagcaat cgtttctgtt ccatccatca agccagccat caaagctcct aatgtcccgt
     2641 gctggtataa gattttttca gtcatgtcga cacttcctta atagaattga tctggtaaga
     2701 ttgtttctcc caatttctca ttatcacggt aatcaatcgg aatatcaata attacgggtc
     2761 cttctgtcgc aaatccttct tctaaagctt tttctaattc ctctacactt gtagctcgga
     2821 ttcctttagc gccaaaagct tctgcatatt tcacaaaatc aactggacca aagtctacac
     2881 ctgacgcccg ctgatatttc attttttctt ggaactctac catattgtag tgtccatcat
     2941 tccaaatcaa atgaacgata ttcaattttt tacgtaccgc cgtttctaaa tcctgggcag
     3001 agaataaaaa tcccccatcg ccggaaactg atacgatttg tgtatttgga cgcaccaatg
     3061 cagcagaaat cgcccatggc aatgcaacac caagcgtttg cataccatta ctgaataaca
     3121 aatgacgagg ttcataactt ctaaagtggc gtgccatcca aatataatga ctacctacat
     3181 ctacggtaac agtcatatca tctgttactt ttgactgaag cgtgttaata acttctaaag
     3241 gatgcaagat acctgcttct ccttttgatt gaacaatgtc ccgctccgtt aattctgctt
     3301 gaagagatgc taaatattct tttgcatctt ctgacacttg ttgaggctct aatgaacctg
     3361 tcaataaatc aagagtggct gagatatcac cgatcaattc tctttcaggc tgcataaaag
     3421 gatcgatttc agctggcgct tcatcgatca caatgatccg cgcatctttt tccgcattcc
     3481 agtttcttgc ttcatattcg attggatcat agccaatagc aataactaga tcacttcgtt
     3541 tcaaaagcat atctcctggt tggtttctaa ataaacccac acgaccaaag aaatgcgctt
     3601 ctaattcacg tgagatcact ccagctgctt ggaatgtctc tacaacaggc aatgctgtct
     3661 ttccaactaa ttgcctgatg gctaacgttt ctttttcact tgatcctcgc atacctacta
     3721 atagtaccgg tagttttgct tctctaatgc gttcagctag gtaacggata tcatctgcag
     3781 aagcagaacc taatttagga tcgctcaatg gcttgatgac attcccttgg acaggtgcat
     3841 ccactacatc ttgcgggata ctgataaagc tcgcgccttt ttttgaactc ttagccatac
     3901 gataagcatt ggcaatcact tctgaaattg tttctggatc ttggatttct gcactgtatt
     3961 ttgtgattgg ctggaacagt gctgcattat ccatgctttg atgggtcaac ttcaatagat
     4021 cgcttcgttt tacttgtccg gcaattgcta aaactgggtc accttctgct gtcgctgtta
     4081 ccaaacctgt agctaagtta ctagcaccag gaccacttgt tgcgataact actcctggct
     4141 ctcctgtaat acgtccgatt gcttgtgcca taaatgcagc attttgttcg tgacgagtca
     4201 cgattaattc aggaccttga tcctctaatt cattaaatac accatcgatt tttgcacctg
     4261 gtataccgaa tacataatca acatgatgat taatcaaact ttctactaca gatttcgaac
     4321 cttgtttcat tttttcgtcc attgaacatc gtccttttta tgctttattt ttaattatta
     4381 gttagaaata atcacaaata attgatacag tttctaaacc tgtttcattc aaaagtatag
     4441 cacgttttat ttcatttgtt tagccatatg tttcaaaaaa tgaaaaagaa tgacagtttt
     4501 tacataaaaa ctgtcattct taattgaaag tttcaattta taaagtctac agatccatag
     4561 ttctcatcaa tttacgattg ttgaagtaaa tcaaaccaaa tacgatagaa ggacctagta
     4621 gaatacacca ttggggcttt acgaaaaaga agagaaacaa acttgtcaat agtaaaaaat
     4681 ctagtaaact cacataccat tttttcaacg tatagtagaa cgctatccgt agaacttgat
     4741 ttggtttcga cgctggattt ctcacctgaa aataccagta gttgatgcta aaggaaactg
     4801 ataaacaagc aagtaaaaca aacaacggaa tcaaccattt tccataagaa aaacgtataa
     4861 aaaagaaaca atcaaaaatc attatcacac taactatcca agcaaatagc caataaaaaa
     4921 atccctttag ccaaaattgg cgaaacgtct ttatgaacaa acgtactggt gaaaaacttt
     4981 tttcttttgc taattcttct gtcataccta tcatcacgat gcaacctgga ccaataaaaa
     5041 gtaaagaaaa aataaaggaa aagacattcc ttccatctat cgacaaaagg aacgcagctg
     5101 ctatatacaa gatattgaca caccaaaaac aaaggctact tgccaatgat tgatacaacc
     5161 aataaaagaa ttccatataa acatttttgt caaaacgctg ctctttcata atcacctcct
     5221 attccttcat tcctgatgaa gcgatccctt ctacaaaata tttttgcatc gctaaaaata
     5281 taaaagcaac aggaagaaca gaaacaactg aggcagccat gattaatgcg tactctgcat
     5341 caaatagccc aataaacatt ttcaacccta actggattgt tttattttcc gtagaagaca
     5401 aataaatgaa tggccccata taatcgttcc atgtattaac gaatgtgatg atcgtcaaac
     5461 tggcaatcgc cggttttgta agaggtaaaa tgatcttgcg atagattccc cactctgata
     5521 agccatcgat ccgcgcactc tcacataaag aatctgggat actactgtag tattgcttca
     5581 acaagaacac accaaaagca ttgaacgctt gtaatagcac caacgaccac aacgtatatg
     5641 ttaaacccac ttttctcatc ataatgaact gcgggatcat ataagactgc caagggacag
     5701 caatcgtgcc gatatatgct aaaaataaaa tatcgcgccc tttaaaattt agtttagaaa
     5761 acccgtaagc agcaaaacta gaagtaaaca actgaatcaa cgtgatcaca acgcttaaaa
     5821 aagctgtatt cttaaaaaat gtcactaaag gaatacgaga ccaaataacc agataattct
     5881 ctaaatgcca agttttaggg atccattgaa tcggaatcgt gaacacttca ttatttgctt
     5941 tgaatgaagc agaaaccatc cataaaaaag gaatgatcgt caataaagct aatacaatca
     6001 gcagaatcat acccaaccat tgaataaagg gcatgttttt tgaacgaatt tttgcttttt
     6061 ttctttcatt tcgaacacct ccaaagttat aatcttcatt tctttgtaat gattacaatc
     6121 cagaacaacg gttattatag ctgattcatt tccgttcttc ttatgtttgt aagcgcttat
     6181 ttaacaagtt atgtaaatct ctttattttt tttgatttaa aaatgaaaaa atacaaaagc
     6241 aagactgtca tacgtctcgc ttttgtattg aaatttcttc gattagagat acttattact
     6301 gttcaaaagc ttctttgaaa cggtgaatca attcattgac tacaggtgat aaaatccgat
     6361 tctttttcca gactagcatg cagttcgttt caatcattgg gtcaagcgga acgaatgtca
     6421 ctcgctttga aagatgactt acagcacctt ctatgactaa agcagcacct acctgattct
     6481 caattagcgc aaatacattg aaaatcaaat tgtacgttcc tgtgatcagc aactgctcct
     6541 tttttatgcc taaccagtca gcaaacattc gctgtatttc tggacgcttt gagatcaaaa
     6601 gaggtacatt cgcaaagtct tcttttgtta tcacgtcttt ttttgctaaa acagaatttt
     6661 ctaaaatgag caatccccat ttttcctttc ttggtaacaa aatcgtttcg tatttctctg
     6721 tatctactgg atctagcaaa atcgctaaat ctaacaggct tttttctagt cactccgtga
     6781 tatcatcact tgttccgctg tggatatgaa attgaacgct gggataatca cggatcaact
     6841 tttctagtaa tagtgccaat gtattcgaat tatcagcttc cacacagccg atcgtaaatc
     6901 ggccgctgaa taattgtttt tttctgttct cgaattcttg agtggtttga ttcgttaaat
     6961 ctaaaatttc ttctgctcgg cttttttaga aaataacctg cttctgtcaa gatcattttg
     7021 cggttttcgc gtacaaacag ttctgttcct agttcctctt ctaactcctt cagttgtcgg
     7081 cttaaggttg gttgtgtaag atgtagaact tctgcggctt gagagattgt tccttcttct
     7141 gcaattgtcc aaaaatattt tagtaagcgt aactccatag cgatgctcct tgattttttt
     7201 acttgataca ttccatttta tttctagata acacacgatc atatttcttg atttttcctt
     7261 gtaaacgttc caaacactct tgcatttcag caatttcttt cgtcaaaagt tcactttctt
     7321 caatcaaaag cttacgccgc tcaaatacag ttgcttctcc ttcgctagat aggcgaatat
     7381 attcaatcaa agactcgatc gataatccgg catttcgcat acagatcgta aagtcgaccc
     7441 attttaggtc ttcttctgta taatcacgga ttccgccttt tgtccgatta actggtggaa
     7501 tcaacccgat tcgttcataa tagcgcaatg tatcggccga aatgcccttt tcttcactga
     7561 cttgtttgat attcatctga tcactctttc tcttaatttc ttgccacttt acttatgtat
     7621 tttatttatt ctacaacttt aagtgtactc caagtcaata ctcatttcta ttaaaactaa
     7681 gctggattat ctatatcggt tgtttgtgta ttatttcaaa taaaaaagtc ttgttttttt
     7741 attctttttt ggatatactt ttaacaattt agggaaattt taggaaaagg ggtataaaaa
     7801 tgacaacgta tcagcgaaag gtattattat cgacatcggc gggaattgct ttagagaata
     7861 tggatattat gtttttagct ttttcattat cttcaatgat tacttctttt catattagtg
     7921 gtacgcaagc gggtttcatt tcaacgatca ctaatttggg gatgctcatt ggaggtattt
     7981 tttttggcat catagctgat aaatatggac gtgtgaaagt attttctcaa acggtccttc
     8041 tgttttcgat tgcttcttta ttgatgtatt ttgcttcaaa catctacttg gtttatctct
     8101 ttcgctttat cgcaggtgta ggagcgggag gagaatacgg ggcgtgtatg tccttgattt
     8161 ccgaaagttt ttcaaaaaaa caaattggac gagcttcttc ggttgctggt attggtgcgc
     8221 aggtcggtgc ggctttggct gcgattttag ctgctgtgat cattccaacg tttggttgga
     8281 agatgttgta tgtcgtaggt gtactgccgg tgttgatggt cttgttcatt cgtcgcggct
     8341 tgactgaacc aaaggaattc aaatctgtac aatctgccga aaagaaaacc aaacttagca
     8401 gactgtttga atcaaaacat cttgcttggc aaacatgtgg ccttagtatc atggtaactg
     8461 tccaaattgc cggctatttt gggttaatga attggctgcc ttcaattatg caaaatcgat
     8521 tagggctttc ggtttctggg tcttcattgt ggatggtcag tactatttta ggcatgtctt
     8581 tggggatgat gacttttggc ataatcatgg ataaattggg gcctaaacta gccttttctt
     8641 tgtttttaat ttgttcatcc ttatctgtct atctacttgt gttagcccat agccagtgga
     8701 gtttggtagc agccgctgtg atagtcggct actttatcaa tggcatgtat ggtggatatg
     8761 gcgcagtgat tagtagtttg tatccaacag aaatccgcgc gacggcgaat aatttcatta
     8821 tgaaccttgg acgagctgtt ggtggttttt cttctatcgt catcggtttc ttgatggatc
     8881 attatagttt aactgccgta atcttgtttt tgagcggtat ttacctagtc agtctgctgg
     8941 tcttgacaac tcttactggt gttacagcat taagggaaag cttgcagcat tgatagttga
     9001 gtctgtaaat gacaagaaag aggtgtggca aaagcttgca tctgcggtaa taagaccagc
     9061 caaatcaaaa acatgagaca ctgtttccgt ttggctggtc gtattacttg atgcagggca
     9121 gctttttcaa ctgctaattt ccttctatct ggcggcgact attctttgac gtccgtcatt
     9181 tcaaagtact ttactaataa cttagcataa cgaaaaactg tggatacact cgtatattga
     9241 gcgtctgcat aatcttccaa atttttctca ggatgttgat acatgaattc aatcaaatga
     9301 taattatatg attttctgta gaaatgaaga taaataatgt agattgggaa gttctcctgc
     9361 ttttccatag aaaagcgccg attattctca ttcttcaaaa tgaccttatc aggatatttt
     9421 tggaacaatt cttctaaatc tgttagataa ttcaagatag acttacttga taccttcaat
     9481 tcgttttgta gttcttctat tgaacaccaa cgttctgttt caagcagtaa atgaatcatt
     9541 ttaattttct tttgagaaac ttttgttaaa aaagtctgca tattttctcc tcctgtatct
     9601 actttactat actacataca agaaaaaaaa cggatacaaa tatcatattg tcacaccgtc
     9661 aatagtgcat aaacctgtta ttatttctct ttttttccta agtattctat tgatatgaat
     9721 catttaatcg tttattatat aaatgtcaat aatctaataa taaaataacg tacatatttt
     9781 attattgcat acttaataac agaactatag caaaaaatcc cgtgtatcaa cacgggatta
     9841 gattaagttt cctcaatcac tattcataac acaattatta taacaagtaa gtaaacaatt
     9901 gaaaaggaca tttattgaaa acggttgttt tttacttaag gaggaaattt agcgaaaaaa
     9961 ttagttgcat tgtttttggt cgcaggaagt ttgttgagtg ggtgtggtgc tactacgtct
    10021 actactcaaa gcacaagttc agatcaggct tccagcagca gtaccacgat ctccgaaagt
    10081 acggcagatt catcgaaaga acaagaacaa attgaaaaga aaaaagaaga gaaacaaaaa
    10141 gcggaaaaag ctgcactaga aaaaaagtga cagaagcgga atctgctttg tcacaagctg
    10201 aagcaaatcc tacaaaagaa aactatgcaa ctgcttcagc agctatccaa gcgctacctg
    10261 aaaacaaaca agagttgaca agccgtcttg ctgcaattga ttccacaatc aaagcaaaag
    10321 aagcagaaga agaacggaaa aagcaagaag aaattgcacg acaacaagca gaacaagcgc
    10381 aacaagaagc aatcgcacag caacaagcag aacaggcgag gcaagaagca atcgcacagc
    10441 aacaagcaga acaggcgcga cagcaatcag cagctgaaca ggcctctcag caggcacaag
    10501 ccgcagctcc tgagcaaaat aatgaacaaa ctgtctatgt cacaccgacc ggttcaaaat
    10561 accatacaca taaatgtgga aatggtacgt atacccctgc cactttaagc gaagctcaag
    10621 ctcgtggttt aaccccttgc tccaaatgtt atggaaacta attcaaaagt tatactataa
    10681 taataaaatt cttctgaaac ataaaaaaat agaagatggc gttccagata gtaaaccaaa
    10741 aataacagtt tacacgtcca tttcgtcagc ttctctcttt tttcatttag tctgttccct
    10801 ctgctttttt ggacatcttc attcattctt tctcaatcaa atagtacacc tctttttctt
    10861 ttcgcagttt atatcttcct tttttcaatt tcattgaaaa ctgtttcgaa tgtttatgtt
    10921 ttacatggat tttaagcagg agctcctcat gttgcaagcg atagttcctg ccttttaaat
    10981 cagaaaatct cactagtccg tattcatcag aagctttcac aaatggaact ttttctctag
    11041 taatatagtg tttgccgttg agcgttttta cagaaaagac cattccttcg attggtcgtc
    11101 cgtttgtgtt ctttacataa aaagataaag gatagtttcg cttagcgatg gccaaagaat
    11161 ctaaataagc gatgagtagc caaactaagc cgattgatcc aagtagtata ccgataaacc
    11221 aaataaaaaa tttccatttt ttccattgat caattccttg gatcgctttt tttgcctctt
    11281 ttgcttgata aggaatacga tgccccgtca caagcagtcg atgtgtattg accatataag
    11341 gagtacaggt aagcaaagtc acgagatctc tgcctttttg gatacccaaa gaatctactt
    11401 catcaggtaa gaccacttgg attttttcta cttgatacgc caatgtcttt ccattgatct
    11461 ggatgaaaaa ctggtctcct tttttcaact taggcaaatc tgtaaataat tttgcttctg
    11521 ggagtccacg atgcccagaa agaacggcat gggtgttttt cccgccagtc ggataagaac
    11581 tttcttccaa taatgacgtt cctttttgca aaaatatttc cgttgtctga tcgaatatag
    11641 gtaagctgac attgattttt gggatttcga tgactccaag catatgttcc ataaaaaagg
    11701 cattactagg taaatctttt aatgcttttg catcaactgc ttggttgaaa ctgcctatcc
    11761 ctggtgatac gttttgctct gccaactgtt ggtttttctt tgtcattttt tcctgctgtt
    11821 tttttatttc ctctgaattc ttattcgatg cttgcttttg ataatggatg atcatttgct
    11881 gggcaagaaa atcattcagt gaatcttcta caaaaggata agaaaagatc ccgatcccaa
    11941 cgactaaaat gattgccatg aagatgtcca gtattcttat tctgctttta ttcatcatgt
    12001 ccacctattt tctaatatgt atatgaagag gttgtgaaat cagcgccttg acctgagtat
    12061 tagcgaagca aacggcaaaa tagttcctcc tattttgccg tttgttgagc gaataccaag
    12121 agaccgacca cttgtcacaa cctttctccc catttgaatc actatcgttt atttatcgta
    12181 tgatttttgt ttccaatagt ttaagcttct gtttcttgat ggcgtttttt gaaatagatc
    12241 actgctcctc caactaaagc agtacctacc aagatgaata cgatgatccc cataccacca
    12301 gttgaaggca agattccttt aggttggtta tcgatcgttg tttcatcaga agttgttgga
    12361 tcatcatcta ctgtaaattc agtgtacgca gcttcattct taggtaatgc gtagccttct
    12421 ggtgcttttg tttcttgaag gcagtatgcc ccttgtttca gcccttcgat tgaaaatttc
    12481 ccttctgaat cagaaatcaa tttcacttct tcccagtcag aacctgtgac ttcatctgac
    12541 caagcatatg ggtattctcc tgaggcaagg tttgctattt ttttcattaa tttaacagtt
    12601 ggatcttttg ctcttagaat agaaaattct gcatcggcta atttttcttg cgtgttcaca
    12661 tcttgtttga tgaagtggaa atcaccgtag ttttggacat tttctacagt aatcgtgtta
    12721 tccgtagttg tattttcccg attgactaca ccgtttggat tcccaagatt ggcttcatct
    12781 gcgccatgga tgataccggt tgtttgttgc aattttccgt tttttactat aaaagtagtt
    12841 tctttttgtg gattggttaa ttgataacca tctggtgctt ttgtttcaac taaagtataa
    12901 ttgccgtcta ttaatccatt gacactgatg gatccttcag tatcagttgt gaatgtcaac
    12961 gctgactcag caggatcata gagagcgaca ccagtgtttt catcaaaacc ggtcacgaat
    13021 tgattctctg aatttttgat ctggaattgc gcccctgcta acttatctac ccctgaaaag
    13081 ttcccagctt tctggatttt gatattgctt tctttgatga catttttagc atataggtga
    13141 atcgtgtcta aaggtttgtc agggtctagg gtaagcttaa cacgatattt ggcgacgttt
    13201 cgacaccggg ctttggtgtt tctacaaaga cgtatacagc atctttccca tcagatttac
    13261 ctggaagagt caggttagct aatccttcac cagaagtcgt tacacttgcg aagggtgtag
    13321 cgtctgctgg aactgctgtg tctttacttg gatagtacgt agcagtgatg tcatatacgt
    13381 tgaattcaac gccgttcaac ggttcgctat tcggaaatgt caattccgtt ccgttgttta
    13441 tttgattttc tggtgctgaa gtgaatttca atttatgcaa attaaccgta acattttctg
    13501 gtgtaggtga tacggctgca gaaacctctg cagttcctag gccgagaacg aaaggaagca
    13561 gcatgatagc agttcctaaa aacgtccata tttttgtttt gatgtttttc attttatttc
    13621 cctcctattg tttccttttt gttgtttttt ataaaaccaa gctgtccctg ttgaaaggac
    13681 tagcaataac cctaaaattg agaaacctcc aagcatctct tcgcttgttt ttggaaagct
    13741 tcctccattt ttttcatttg atggaccatt tgtctgcatc tgaactggcg tttttccatt
    13801 attcgtcgga tttgcttttg gttcgttgat gatttccaat ggtataggat gaagcggatc
    13861 ataactgcct ttttcaactt caaagagaat ggttgattga ctcaatatat atcctttagg
    13921 cggtttaatc tccactagtt cgtaacttcc aaaagacaat ccatggacag aaaatgttcc
    13981 atctttactg gaagtaaaaa tcgttgctct tgaatcatct ttggctaccc aatgatttat
    14041 cccgttttct tgcgctaagt attggtcatt ttttttgact agaaattgag catctgctag
    14101 tttttgtttc gtttgccgat ccactttgac aaattgtttg cctcctgttt ggatggcaag
    14161 atgtgtttct actgtttgat tgtcagtcgt caaacgtaca tcgttatcaa atgtcgtttt
    14221 ttcactgttt tctttcaatg tcatttggta acggatcgtt aatttttttc cagcaaacga
    14281 actaagatct tttccagaat ctgataagac aaaaccatgt tttatttttt gtgtgtgaaa
    14341 tgtatgaatc ttgtctccac caatcaaaaa atcgatcgtt tctggttcta gccataactg
    14401 aggatcagct gtatctttga tcgtataggt tcctatctcg ttgatgttct caggaattgt
    14461 tacggtgatg agataaggga ctttatcccc atctgcaaaa tctgtctgct tattctctac
    14521 tgtttttgtt aatgtgagtg cagcaggtat tttttgttcg ctctttggat acaagtggat
    14581 ggtcgtcaat ttatgattag atgaatctgt cacaggaagc acaacgacaa atggtgctga
    14641 tttttctttt acttaatctg aagtctttat ttccgtaaat cggtaaacag cgtcacgacc
    14701 ttgctcatct ttgtccgatg cactaaaaga agcaatgccc tcttcctcgt ctactgtttt
    14761 tgtcacattt tctgccagta ttttttcact atcacttttt tgtgctagtt ttctttgtgc
    14821 gtcttccaca ctacttcctt ctgaccgcag cttgtaaaat tcatccgaga catcatatat
    14881 agcgaaagta acgccgttca acccttttac tccttgaaag ttatccggga tatttattcc
    14941 gtcgttttga ctgatacttg gcatcttatc gctttcgaac attcgattat gcaaagtaaa
    15001 tgtaataggt gattctctag ctgacacagt cggagaacct ataaaaaaga ccagtaggat
    15061 aaaaaagaga acagcaaata tatccacacg tacatttttt gtttttttca tcgctgttca
    15121 cctgcttttt tcttacgatg gataaaataa aagaagccag aaaaaataaa gatcagtcct
    15181 aaaaagacaa agggcagtag acctatccca cctgtcgaag gaagcaagag agtcggattg
    15241 atcgtcaact tagcggtatc tgttgcgata atcgtataat tattgtttac acttccttcg
    15301 cctaaactaa tcgttactat ttgtgatcca atatctgtcc ggctgttaac tgttagggta
    15361 taatccaatg attcgcctaa gacaacaccg gtaacgtgga gatttccaac cgaaatcgag
    15421 tgactttggg catcataatt aaaggcagcg tcatcgacag taatcactgc gttagcttta
    15481 tagatggtat aagttcctga tgtgttggct atatcagtaa atgacaactt gggatttgct
    15541 gctttgactt tgtctattcc gctattcgtt agtttaattg tatagctgcc agcattaacc
    15601 atattttttg ctgattgtgc atctgctgtg taatccatac tgctaagtgc cacttgtact
    15661 ggagtaagcg aactagtgac accctctgct agcttgacat ggattgacgg gacacctgct
    15721 tttccatcat atgtcttact gccactgagc tctaccgcac cgctgatttg cttaatcgta
    15781 tagacatcag atgtctgcac gatagtaaat aaatagtttg ttctggcagc tagtttagct
    15841 agtccgcttt ttgtcaattg ccaagacgta taggttccaa tttcagtagg cgcagttact
    15901 tcaactccct tttcattcat cgctttgaaa tcagttggat tccatgtgat ttgatcaata
    15961 ctgagatcat tgtttaaaag ggatgttgat tctgttttat cattaaaggc atatttaacg
    16021 atcggtacaa cagaaagacc atcatagtac ttactgccat ttgcattgat tgatactgtt
    16081 gcatttgtct tataatatag gatgacttca gaaatctgtt ttccatttgc gtcctttacg
    16141 attacatttc catttgtatc taaactagct aaaacactca ttgctgattg gttctttgtt
    16201 tctatcgctg aaacagctgt aaaggtatat ccgttgatag taggcgtatt agtcgtcagg
    16261 tcttgtgcag cacttccgta agtaagattc attattttag aaggagcaat catctgtcca
    16321 aaatagtctt gatacttaat agtgattggt gtttgtttgc ctgtataggt caccgtatcg
    16381 acgttacttt ctagggctgt gaaagaaccg tttgtttgtg caaaagaata gcccgttact
    16441 gctgttggag tgataaccac tttgtcaccc acatggattc cagataatgt agtcccgtac
    16501 gttccgattt ttgctgctcc accattgact gtataagaaa aagttcctgt ccgattcgca
    16561 ttgacctgaa ccgttgctgc ttgataggtt ggaaaatttg aaacatttcc cttaccatca
    16621 acgatctgcc catttttgat cgagtacccc gtgaatggaa tatcatttgc taactgtata
    16681 ccgattgaaa aagtactcat acctcctccg gcaggaagcc ctccccatgt tgagggtgta
    16741 aaagaataac ttttatccgc attgggtgta actgaatcga tcgtatttcc agcggtagcc
    16801 acccccatat agatactttt tgggaatgtg atagtagtac catttactgt ggagccaata
    16861 aacagattat ggatatctgg acggttatca ataaaagcga ttgctttggt tacgccttgt
    16921 aacgcagttt tatccgcact catcgatccg ttaaccgcaa caatgactcc atctttggca
    16981 tatatcactg tatatccatc tggtatggta tgtccgttga aattcgcagt ggccgcaaca
    17041 gtactaaatg tctggcttct acctgtttct gaataagctt tctcccctgc tgcttttgct
    17101 gctgtgattt ctttttctgt cggatcaatc agttgagtcg aggatgtggt tgaggttgtc
    17161 tcgttgttgc tagactgatt ggtgctttct atggactgta tttcagaata gggtggacta
    17221 tttgtctcct ctgtcgtttg gttagcaaaa tttgacgttt ctgtataaac gtttacataa
    17281 atacttgata agctccctaa gaaagtaaaa atcaagatga tcgaaatcat aatgggatgt
    17341 aagtattttc ttttagatac agctttgagt ctagaaacaa aatgtttttg acatatacgt
    17401 tggattttat tttgagtttt cttaatcatt ttcatccctc ctctcaataa aaaatcatca
    17461 aataatcctt tacacgttat tctaaattta atttttatta ttttattgat gtatagaaag
    17521 tttggggctt ttt
//
LOCUS       DBBGRF010000058        16590 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000058 DBBGRF010000000
VERSION     DBBGRF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.058"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(79..786)
                     /locus_tag="ACIZD4_002321"
     CDS             complement(79..786)
                     /locus_tag="ACIZD4_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HGC5991207.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(865..1203)
                     /locus_tag="ACIZD4_002322"
     CDS             complement(865..1203)
                     /locus_tag="ACIZD4_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGC5991208.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(1314..2276)
                     /locus_tag="ACIZD4_002323"
     CDS             complement(1314..2276)
                     /locus_tag="ACIZD4_002323"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGC5991209.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(2291..3622)
                     /locus_tag="ACIZD4_002324"
     CDS             complement(2291..3622)
                     /locus_tag="ACIZD4_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HGC5991210.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(3630..4310)
                     /locus_tag="ACIZD4_002325"
     CDS             complement(3630..4310)
                     /locus_tag="ACIZD4_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HGC5991211.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(4529..5008)
                     /locus_tag="ACIZD4_002326"
     CDS             complement(4529..5008)
                     /locus_tag="ACIZD4_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGC5991212.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(5135..6814)
                     /locus_tag="ACIZD4_002327"
     CDS             complement(5135..6814)
                     /locus_tag="ACIZD4_002327"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGC5991213.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            7362..8864
                     /locus_tag="ACIZD4_002328"
     CDS             7362..8864
                     /locus_tag="ACIZD4_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5991214.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVTVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            8877..9539
                     /locus_tag="ACIZD4_002329"
     CDS             8877..9539
                     /locus_tag="ACIZD4_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5991215.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(9640..9843)
                     /locus_tag="ACIZD4_002330"
     CDS             complement(9640..9843)
                     /locus_tag="ACIZD4_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGC5991216.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(9954..11138)
                     /gene="iadA"
                     /locus_tag="ACIZD4_002331"
     CDS             complement(9954..11138)
                     /gene="iadA"
                     /locus_tag="ACIZD4_002331"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HGC5991217.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(11295..13034)
                     /gene="yfcC"
                     /locus_tag="ACIZD4_002332"
     CDS             complement(11295..13034)
                     /gene="yfcC"
                     /locus_tag="ACIZD4_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HGC5991218.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(13807..14421)
                     /locus_tag="ACIZD4_002333"
     CDS             complement(13807..14421)
                     /locus_tag="ACIZD4_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGC5991219.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(15027..15404)
                     /locus_tag="ACIZD4_002334"
     CDS             complement(15027..15404)
                     /locus_tag="ACIZD4_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991220.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(15704..16585)
                     /gene="galU"
                     /locus_tag="ACIZD4_002335"
     CDS             complement(15704..16585)
                     /gene="galU"
                     /locus_tag="ACIZD4_002335"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGC5991221.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         4808 a         3574 c         2832 g         5376 t
ORIGIN      
        1 ttccaaataa atggtattca atcagctaac tctcggtatt agctcagatc aaagcgctga
       61 tttcacaact tctttatttt aatctcttcg gttgccgccg aacaataaga tcaagcgcaa
      121 cagctgcagg aatgtcgaaa gcgctgctgc aacataagtc agtgctgctg caaataatac
      181 gtgtcttgcc atcggtactt cttcttccgt cagtagtccg ccttcactca aaatttggat
      241 tgctcgccga gacgcgttaa attcgactgg taatgtcacc aattggaaaa gtaatgctaa
      301 agaaaaagcg aaaatcccga tattgattaa cgtagagttc cagctaagca atacacctac
      361 cataatcaag gggaacgaaa tcatcgaacc aaagttagct gctggaacaa gtgctgcacg
      421 aatcttcaat gggacataac ccgaagcatc ttgtaccgca tgtccgcatt catgagctgc
      481 tacacctatc gcagcaactg aagtagactg tgcagttgct tgagacaaac tcaacatctt
      541 attacctgaa ttgtagttat ctgtgagatc tccggcaatt tgttgaacac cgacattatt
      601 tatctgttga ctttgtaata tatattgtgc tgcttgtgta ccagtcacat tgtttttgct
      661 tctcacttga tcgtattttc ggaaagtact attgacgtac gctgacgcaa ttccggaaat
      721 aactaatcca agaatgacca aaagaaatgt cggatctaaa aaaccataca ttccataacc
      781 atacattttc gtttcactcc ttttcgttta ctttatttta tcattagtag taggaaaaga
      841 atgtgaaaag accttgaata ttctttaatt ctttttcaca aattccgatt tcagtttcat
      901 cggtccaaat ccttctacct tgcaatcgat attatgatcg ccttctacta aacggatgtt
      961 cttgactttt gttccttgtt taatggcacc tgacgcacct tttactttca agtctttaat
     1021 cactgtcacg ctatcgccct ctaacagacg gtttccattt gcatctaata ccactaatcc
     1081 gtcttctatg acagtttctt gttcttcttt gttccattcg ttcccgcatt ctgggcaaat
     1141 caacaagcct cgatcttcat atgtgtactc tgagccacat tctgggcaat ttggtaatgt
     1201 catcttcttt ctcctttaaa atctttagtg agcactattg taacggaaaa agaagatctt
     1261 gaaaagatac atttgtgatt tttactacaa aaggcacgtt ttcgaacgaa gtatcattct
     1321 gtttttctgc tcttatacga ttggcatata tcttggatct ctttatagat ttcctctact
     1381 tctgctaaat cttttgcatt cgcaccactt gctaatggat ggcctcctcc atgatggcgt
     1441 ttagccaatt cattgatgat cggcccctta gaacgtaaac gtacgcggta ataccctgaa
     1501 ggctgctgaa caaaaatccc ccaagccagc acttcgtcaa tcactccagg aagtgaaacg
     1561 atcgaagctg tctctgaatc atcgattcca tatttatcaa gaatttcttg cggaaggatt
     1621 attcttcctg caccattttc atccacctgg atattttgat aaagataacc ggaaagttta
     1681 gcgactttca tcggcatttg ttcaatctct ctgttcaaag cacttgcatc aaatggataa
     1741 tttctcaata tcgaagcaat ctctaatgta cgggacgtcg tggagggata caaaaagcgc
     1801 cctgtatctc cgacgattcc tgcataaagt aaccgtgcag ccttaacgtt catctttaaa
     1861 gattcaggaa acatcaaagc aaattctgca atcatctcac tacagctact tgcttttgta
     1921 tttacccaca caagatctcc ataagggtca tcattgggat gatggtcgat tttgatcagt
     1981 ttttctgcca actgatatct ttgatcactg attctgggtg aattagctgt atcagtcacg
     2041 atgactagcg ctccttggta gaagacatct tcaacttctt gcatttctgc taaaaagcga
     2101 agcccttcaa tcgtttcacc tacttgacgt atttcttttt ctgggaaact ttcccgtaat
     2161 agttcggcta atcctacttg tgatcctaat gcatcaggat cagggcgcaa atgcctgtgg
     2221 ataatgattt tatcgtattt ttttattgta tctactattt cttgctgtac tgtcatttca
     2281 ctcctgcttt ctaagaacgt tccattactt gacaaacaac gattgctttg gaaacgatgg
     2341 tgttttcaat aaacacttcg atatccagtt tagcggaacg tctgccgatt tccaatacac
     2401 gtggacgaat gtctaattcg ctttccaatt ggatcagccg caaataatgt aggttcactt
     2461 gttcaatcaa gatatttcgt ttttggttca tcaccattgt tttttgtgcg acatcagaaa
     2521 tgatttcgct aagtacgcca aaagaaatgg ttccaacgcc attgaccatt tgtggtgcta
     2581 ctacgaattt gaacttaggg ttttccaaac gatttccttc acggtcagta tcaatcgtat
     2641 ggatatttcc agatatctga tccgaaatcg tatctgcaat ctgcggttgt cgctggacaa
     2701 gctgcatcgc tttcattaca tcttgccggg taatcaagcc ttccaatgtc aagtcatcgg
     2761 aaacgaccgg catgacttct agcccatccc agatcatttg atggctaaca gaggcaatac
     2821 tcattgtttt ctttacactg attggttctt tcgtcatcac ccgatcgatg atctggtttg
     2881 gcgatttccc taaaacatct tttgccgtaa caatccccat caaacgatga tggcggttga
     2941 cgactggaaa acgcgaatgc tgcgtttctt ctgacaaacg ctgataatca gaaatcgtat
     3001 ctgtctgctg caaataatga gtcttttcag ctggcatata gatatcactg acaagcatga
     3061 tatctttttt gatcaattgg tcgcttaacg ctcggttgat catggttgcg actgtaaatg
     3121 tatcataaga ggtgcgtaag atcggcattt caagatcatc agctagcttt gcaatctcag
     3181 cagtcgtatt gaatcctcct gtgatcaata ctgcggcgcc atcttccaat gctaattttt
     3241 ggacttccgc ccggttgccg acgatcatta gtgatcctgg cgtaatatag cgttccatgg
     3301 catgtttagt catcgcgccg atgacgaatt tattcaagac cttgtctaat cctgccgccc
     3361 cgcctaaaac gtccccttca atgatcctga cgacctcgcc aaatgtcaaa cgttcaatat
     3421 gtttttttaa tttgcgttcg atacggatgg tccctactcg ttgaattgtt gaaactagtc
     3481 cgacattttc tgcatctttg attgcacggt acgctgttcc ttcactgaca ttcaattctt
     3541 ttgcgatgct tcttacagaa attcgattgc caacaggtaa actttcaata tattctaaaa
     3601 tcaaatcatg ttttgtcgcc attttctgcc tacacttcca gcgtttccga gacgctcatt
     3661 atttttcctt cactatcttc cagtaactct acaaaagatt cgggatcttg ttcaatgaca
     3721 gggaaagtat tgtaatggat tggaactact ttcttggcac gaattgtttg cgcagccttt
     3781 gctgcatctt ctggccccat cgtatagtta tcgccaatcg gcaagaaagc gacatcaata
     3841 tcgaattctt ctgcaagcaa tcctagatca ctgaaataag cagtatcccc tgcatgataa
     3901 atcgtttttc cttctgcttg aataataatt ccgctaggct cgcccatata ctgaacgata
     3961 ccgtctactt catagcttga actatgctgt gcatgtacga attttaccac gccgaatgga
     4021 aacgcatgtt ttccaccgat attcataccg aatgaatcta ctcctctgct gttcgcataa
     4081 tcagcaatct caacaatact gataattgtg gcttgatttt cttttgcaat aggaatcata
     4141 tctcctatgt ggtcactatg accatgagta atcagcaacc aatctgtctt tacttcttct
     4201 gcagttaagt ctgtcaatgg atttcctgta ataaacgggt caatcatcac gcgttggcca
     4261 ttttccattt caattgttaa acaggaatgt ccatgatacg taattttcat attttacacc
     4321 tcgcgttttc tctgtatctt ttttattaaa aacgatttca tcacttgcac atcaatgaaa
     4381 aaatatagct gctaaatata ttttcattgg attgatagta cagtatgtac aaagcaattg
     4441 taacagataa tacaggatgc accaagtacc aagcagatat aatctcaagt ttgaggtctc
     4501 tgctctgctt agcttctctt ctcgtccctt aactaattaa atcagcgtaa ataggatgga
     4561 cgatcttttc taaatcggct acttttatcc gaaggcttct cccgatttca ccgcttgaca
     4621 caattacttc ttctttttct tttaaagaac tgtctgctaa aaaacaataa tcaggatgtg
     4681 cgagttttat tccaataggg gtgtttgctc cgtggggata tcctgtatgc attaatacaa
     4741 aatccattcc aggaaaacca actttacgat ctttcgtcac ttgtctcgtt tttttgtaat
     4801 ctaagtgatc gttcaaagga atcaatgcga tgatcacccc agttttgttt cctttcacta
     4861 cgagagtttt acatatcaaa gctggatcaa tccctctttt ttgtagttct tctgtgaaag
     4921 attcttctac cacatgacta aaatcaagtg gttgatagct gatcttttgt tcttctaaat
     4981 aacgttcgac ttttgtttga ctcatcattg attcactccc tttattctat cgtttattat
     5041 aaagcgaggg atgctgtatt caaaaattat ttgtttttcg caaaaaaaga gcaagacgag
     5101 cactctatag agaggttcat cttactcttt ttgtttattt tttatttcga cgttgagtag
     5161 cttccataat gactggcaag atcactgggc ggcgttttgt ttgttcaaat aagtaacggc
     5221 ctaattgatc tcggatgtct tgctttaatt tgctccactc aaaatcattg ctttctaaat
     5281 gtttctcaac gattgtttca atcatattgc tgctttcttt catcagatca cggctagctt
     5341 ttacgtaaac gaatccccgt gaagtaattt gaggttttga aatgattttc ttttctcgcc
     5401 gactgatagt gacaaccgct acgaaaatcc cgtcttctga caagattttt cgatcacgta
     5461 aaacaatgtt tccgatatca cctatgccta atccatcaat cattacattt tctgcacttg
     5521 tagttcctgc aacactcata cgcttgttct tatattccag cacgtctccg cgtccagtaa
     5581 tatagatatt tttgtatggc atccctactg catgagccaa atctgcatga gcagctaatt
     5641 cacgatactc tccttgaact ggcacaaaat atgttggttt catcaaattg atcattaatt
     5701 gcaagtcatt aggattggca tggccagaaa cgcgcatatt ctcagagatc aacttcactg
     5761 ttccaccagc tcgataaatg atatcttccg ttttcgccac gatggtttcc atcgcgatgc
     5821 ttggcgtagt agtgatataa accaaatctc cttcttcaat cttgacatta cggtgtgtac
     5881 cgtttgccat tttttgcaga gacttgatgg gttcacccat tcggccagtt tctaaaatga
     5941 tcagttcttc tggatcatag tttttcatgt ctttcaacgt aacaagcaga tcttcacttg
     6001 gtaattgaag tttttctaaa cgcatcgctg tgcgaataat tcgttcgaaa tcttgaccag
     6061 tcaagacaac ttttcgttgt gctttttctg ctgcatccaa tacttgttgc actcgttgca
     6121 aattacttgc tacacaagcg acgatgatac gcccttccca atatttgatc gtatcaaata
     6181 cttcatctgc tatttgggct tcagaagcta caggctgagg attttctgca tttgccgatt
     6241 cacttagtaa ggctaagact ccttctttgc cgatttccgc caatcgtgca taatctgttt
     6301 gatacattgg gatagccgtt tggtcaaatt taaaatctcc cgtataaacg atactacctt
     6361 cttttgtttt cagattgatc cccactgaat ctggtatcgt atgagtggta cggaaaaagc
     6421 tcactactgt ttcaccaaag tctatttctg tatgctcatc taccacatgg aaatccttaa
     6481 atcctttggc tgcttcatta cgactgacat tcaattttgc taactcgatc gtcaactctg
     6541 tcccgaatac tggtacagaa atttttgaca acaagtaagg aagtgccccg atcgcatctg
     6601 catgtccatg tgttaaaaag acaccagcta cacgatcaat gttttcttct aaatacgtaa
     6661 aatcagggat tacgacgtcg atccccaaca actcattttc aggatatttt agcccacaat
     6721 ctaaaataaa aatatcctcg cccacttctg cgacatacat gttttttcca ttttcacgaa
     6781 cgccgcctaa tgggataatt ttaatggtac tcacaaactt cacctcttct tatgacatcc
     6841 aagtttaaag atgtcgattt tcttctttat ctaaatatat gagccattcc aatgaagcat
     6901 atgcaaaatc actatttctc aacttatgga gaatcagcag gaaaattacc agcacatccg
     6961 cgttctgaca gttggatggg cattttattt tggatatact tcattaacaa aatggatctt
     7021 ttgcgaaacg ctatagccag aatacttata taagtattca gctgttcccc attattatac
     7081 aacaaataaa ctaaatcgct agtatcagca attgttagaa caactatgca cgtaaaaatc
     7141 cctctgtagc atctaggatt tcttttgcta ttcctctttc atttcttctt cgtcggtttg
     7201 aaacatactt ttttcatttt accacatttt ttgcaataac tatagtgact ttttatatat
     7261 acagaacctc atgttgatgg tgtgcaaaca gcataagatt taagctagct ttaagatagg
     7321 ttgtctatta tcaaatgcat ctactaggag ggatgcaaaa tatgaatttt atgaaacgtg
     7381 catggaaaag tacaaaagta aaatggggac gttcattgtt attgtttgcc gtgttcacag
     7441 ccattcttat ttttgtgcta gctggcctca cgattcgaag cgctgcagaa gaagcagcga
     7501 atcaagcaca aaaagaagtt ggagcaacag tgactttaag tgccaatcga gaagcttcat
     7561 ttaaaaaaca ggaacaaact tcttcaagcg gttctaccac tgaagaacgt ccagatccag
     7621 gcagtttttc tcttacacca gtttccttaa cggacgcgga aaaaatagct gaattagata
     7681 atgtaaagag ttattccttt gaaagttccg cctcagctat ggcaaaagat ggaataactg
     7741 ccatcactag ttctgattca agtgaagaca gttcagaaac tactgatgca ggcggtgaac
     7801 ctgctggagg aatgggcggg aatccgcaaa tgactcaagc agactttcaa atcagtggtg
     7861 tgtcagcaac tgcacaaaat agtaattttt ctgatggaac agcaaaaatc acggatggtg
     7921 aaggaataga tgacagcgac aaaggcacaa acaatgtagt cattgattct actctagcag
     7981 aaacaaatga cctggcagtc ggagatactt tcacaatcac gagtactgaa gatgaagata
     8041 ccacttatga aatgacgatc aaaggaattt atgaatccag cgaaacaagc ggcagtatgg
     8101 gtatgaaatt caacttcatg aatccgtcga atacacttta cacttcttac acttttgcaa
     8161 atgaactaaa tgggacatct gacgataaca cgatagattc tgctatttac actctatctg
     8221 atccagataa aatggatgag tttctcaaag aagctgagaa gctgatcgac acagatacat
     8281 ttagcttaca atcaaatgat tccatgtatc agtcaatgtt ggaaccttta aacaacgtgg
     8341 caagtttttc taaaaatgtt gttttactag tgactgtagc cggtattatc atacttactc
     8401 tgatcattat gattaccatt cgggagcgtc ggcatgagtt aggcgtcttg ctatctttag
     8461 gagaatccag aagtaaaatc attctccaat tgtttaccga agtggctatt tgtatgattc
     8521 ttgcattagg agttgcttcg cttagcggaa acgtcgtcgc gaatgccgtg ggacagcagc
     8581 tacttgacca acagacagaa accacgacac aaaaccagca agctcctggc ggtggacaaa
     8641 tgccaggtaa cagacaagaa caaggcggtc aacgcgatgg tcaacaagga accacgaata
     8701 atccatttgc tgtttctgat caagtcagcg aattggaaat caatgtcaaa cctgcacaat
     8761 tgggactatt agccggagta gcatttggaa tcagtctgtt ttctgtcttt ttagcttcta
     8821 tagggatatt aagattaaac ccaagaaaaa tcctattaaa ctaaaggagg aatttgatgt
     8881 tacggacaga acaattggga ttttggtatc aagatccgca agatgcgctt tataaagatg
     8941 tagaactgaa tttcgaagct ggaaaaatgt acgctatttt aggagcaagt ggttctggaa
     9001 aaacgacttt tctttcgctt atttctggac tagatgcacc aaaagaagga aaggtatact
     9061 atcaagatcg ttcactgaac aaaatcgggt taagaagtta tcgtaaaaat gatgtctcga
     9121 ttattttcca agcttacaac ttgcttcctt atttatcggc tctagacaac gtcatagcag
     9181 caatggaaat cactaagacc aagcaagaga attatcgaca agttgcttta gatcgactgg
     9241 ctcgtgtagg aattgatgaa atattagcaa aaaaacaggt gaccaaactt tcgggaggtc
     9301 agcagcagcg agtcgctatc gttcgtgcta tctgctgtga acatcaacta atcgtagcgg
     9361 atgagcctac tggaaatcta gatgaaacaa cttcacaaga tatcgtcaaa cttttccaag
     9421 aaatcgccca tgaacaaaat cgctgtatta tcatcgtgac tcatgagatt gaagtagcaa
     9481 aaagctgtga tgaagtcttt gaactaaaaa ataaaaaatt tcaaaaaatc gaagtttaaa
     9541 aaacaggata atgatcaaat aaaaaatccg aaccatatct gtctcgcaga tatggttcgg
     9601 attttttatt tgcttgattc aattagtaat aagtggtttt tatttttttt cgtcttttcg
     9661 agaaaacttg tctttgactt cgtcgcctaa atttcgagct ttttctttga tgtcagcacc
     9721 tagtgattgt gctttccctt ctgtttcttt gctcttgtcg tctgttgctt tgccgtatgc
     9781 ttcttttcct tcaccgacta ctttatcttt catatcttta gaacgtcctt ttaaatctgc
     9841 cattgtgctt cctcctctta gtttgtttat tgatctacct tcagggtaac atcaacaaca
     9901 gatacagaca aacagaacgc tcgttttcta aaaaagatag ttagagctgt tgattaaaaa
     9961 cttttttcga aagtccccca tactttgact tctttttctt ggaccattat ttctccttta
    10021 gcgataactg tatcaatatc aagcgtttct ttatccaaga tacacagatc tgcatcagca
    10081 ccaatttcga tttttccttt tttatccaat ttcaatatac gtgctggatt actggttata
    10141 gctcgtaagg cgatttccaa agggatactt tctttttgca cagcttcttt gatccctact
    10201 agcaatgcct tggcacttcc tactcctaac cctaggaaat gattgttttc atcaaaataa
    10261 ggcaagcttc cttgtccatc tgaggtcatc gtgaaattat ctaaagaaac atcttcctcg
    10321 atcaatcgtt tcagtgcttt gctgaagcga acttcaccat ctgtcttctc ccaaaaatca
    10381 ggatcttcgc tagcagtgaa gtcaatcgtg ccaccacgtt tggcaaatgc cacgcaagct
    10441 tcaaataatt ctggtgtgcg atttgcatga gtaggcaaaa attgtgtgat cggaatttct
    10501 gtttcttcta cgattcgtgt caatagctct agctttcttt ttcctccgcc taagtggaca
    10561 ttgatgatcc cagcttttcc ggataacatg cctcctacac gagcatctgc tactgcacga
    10621 gcgaactctt caaaacttgg ctgagaagaa cggtgatcgg atactgcgat ttctccgatt
    10681 ccgataattt tatcaattgt caaaaagtct ttgatgatag aatctgttac tgtttttacc
    10741 ggcaatcggt acgaaccttc gtatacataa gtggagattc cttctgcttc cagacctttc
    10801 gctttgctga tcaacgcagt catatctcta ccttctccgt ctgttcccaa acaaccgaca
    10861 actgtcgtta caccagctgt agtcaattgg ctcaatgtga cttctggcgt tcgattttga
    10921 taaccgcctt ctcctcctcc acctaaaata tggaaatgac agtcaatgaa acccggggtt
    10981 agtacttttc cctcacctga aagttcttct acttccactc cttcgtagcc gccttctagc
    11041 tgttcttcta cagccaaaat cttcccaccg gcaatcagta catccatttt tcctaagtaa
    11101 tctggtgcaa acacttcaat ttgtcgaatg attttcatac atttttcctc tttctttaag
    11161 tataactgat gataggatct taaaaaataa tccaaacgat aggatcttta ctcctttgat
    11221 tttaccgtaa aatgacggtt cttggagtcc ttatctactg tttggattac ttttttattt
    11281 acaggtctcc agtactactg cagacctatt gcaatggcaa tcatgatgaa aatagttcct
    11341 aaaacaaaca ggaatccttg catcttgatt tggaatcttg cccattttgc ccattcgatc
    11401 cgtgcaacac ctagcacacc aatcaagctg gctgatacgg gtgtaaaagc gtccataaaa
    11461 cctgaaccaa gctgataagc aagaactgct acttgtctgg atacacctac taaatctgcc
    11521 agtggagcca tgattggcat agtcaaagct gcttgtcctg aatttgatgt aacaaccaag
    11581 ttgaacaaac tttggaagat gtacatcgcc caagcaccaa tgacagctgg aacaccggtc
    11641 aacgccgtcc cgatcccatg caaaatcgta ttcaaagctg aaggaacaga tgcatcagat
    11701 cctcccaaga caagaagaat ccctttggcc atacctacta cgattgctgt accagctaaa
    11761 tcagctgcac cagattggaa agaagaagcg atgtcattga ctttcattcc atctaatttg
    11821 aaaagaacag caatgattcc agcaactaat cccatcacaa agaattgaga agcgatttct
    11881 ggaatgtaat agcctttttg agtcacgccc caaacgatcc agacaaggac aactaacatc
    11941 tctaataaga tcaatttatg cccaagcatg aattttttat tttcatcaga tgtctttttg
    12001 atatgagaac ggaaataatc atctgatttg taagtcaacg aactttctgg ttttttacgg
    12061 attttttctg catatatcat catataacca gcggctaatg cagtaacaac tacccacata
    12121 atcaatcgga atgtcgcacc agacaacacg gggattccag caatcccttg agccaccgct
    12181 acgctaaacg ggctcatcca agaggtcgca tttccgactt gagatgcgac ataagtcacg
    12241 gttactgcta cgatcgagtc atatcctaac gcaatgacaa atggaaccat caccattgag
    12301 aatggaatta cctcttctgc catcccgaat gtagcgccac cgaatgaaaa agcaaagaat
    12361 aatagcggta aagctaaacg ctccagtccc ttagttttac tgataaacgc atagatacct
    12421 gcgtcgatcg ctccggtacg cataataata ccaaaagcac ctccaacaac aaggatcaat
    12481 gcagcgatcc ctacagcaga tccatactta tctccagata ctagtccttc aaaaacaaaa
    12541 tttaagaaac caaagccgcc aaaatcatct gttccccata ttttggctgt tttatgcaat
    12601 tttttagaag tatcatagat attttcgccg tactgatcgt aaagcacatc atctgtcaag
    12661 gagatttcat ctagtttttc ctgcgtaaga tttttttctc cgtcagcaat gactttttcc
    12721 aatccttttt ccggaacatc cagtttttca cgttctgctg gatgatcttg cagttcttct
    12781 aattgatcaa acacatacga cttatccagc tcgtaagcat aacggaagga atcttgacgt
    12841 aaaacagtac gagtacttgt ttcgccattt gcatctttgt attcaatatc ttgcgtgctg
    12901 aactttcctg ctggaacgac aaaagtcagt atccatgcaa agatgactac accaaaaata
    12961 atgacatacg tatggggtgt cgataattta gtgaagtcgc gtttcggttt tcctgaagaa
    13021 tttgttttct tcaaatttat ttcttccttt cttttttcag taattttgat gaataaaaaa
    13081 tggataatca aatgaattat acagtaaaaa tgacatttcc acatgaataa tttattagaa
    13141 aatcactttt ttctattttg ttttttttct cctatgtatg attatttttt tctctttcca
    13201 tttatattaa gtattttatt tctctgtttt tccttaaaat tcttttttta tttttagatt
    13261 agagaaaatc tcgtcctgtt tttttcattt tacaatcatt gaaaaattga atttcattgc
    13321 aaaaaaaata ataaacactt ataaatatcc attatctatc cttcaatttt tgtgtatttt
    13381 atttctatta gaaaaaggta tcctgttgga caattttgtt atatcaggta aacttcattg
    13441 caataatgat aacaaatgta ctataattac tttgtaaaga gttttgggga agactctttc
    13501 atcaacgtgt attaagagac aagaaagaat ccatatggat tctttcttgt ctctttttcc
    13561 actacttttt atttttctga cactacatat tcttataact catttctcat aactgtgaaa
    13621 caacttataa aaataacaaa ctttaaacaa aacaagctta aaatcaaaga tgatccatct
    13681 taaaataact aaaacaaaaa aagtagtcgt tgttaatcct cattaataat cgttttcttt
    13741 ttttcaaacg ctccattttt atgtggaaca ttattttttt aaggaacttt gtcaacatgt
    13801 ggataactat tttccacttg tgtcctggac tagctgtttt gctgtaaaat acaaaacttg
    13861 ctgcagcaaa aagatcgttg caagagaggc tgttccgcag atcgctggat ctagatttgg
    13921 caaagtcaag actgcatcat gtaaattggc gtggttgtcc aaaaccaaat cagcaaattc
    13981 aaataatcgc aaaccactgc tatgttgcga tttgatactt cgtgacaaat caaatccagt
    14041 aacaatgatt aatggatgac cattttcttt gatccactga gctagttcga tgattgccgg
    14101 gtttcttcct tcattcgaaa gaagaagaaa aatgtcttct gatttgacag aaagctgatc
    14161 aataattgcc tgtcctgcac cttctagcgt ttcatagaca cctccggctg gattttcaat
    14221 caatatactt ggtacaagat ccggggtttg atcccaaaat tcaaatgcta caccacttag
    14281 tgtgcggcta gcatatatct gcaatctacc accttgatta atttgtttcg cgatccaagt
    14341 gccagcttga agcatcagcg gctcttctat ccttaatttc tcttccaatt ggtgataata
    14401 gtcaaaataa cataaactca tttatctctc ccgcctagct atacttgaca tgaatagaaa
    14461 cagctgccta atctaaggaa gtacataaaa aaacagtagt tagacagtaa cacatgtggt
    14521 ctttgctgtt tcaaacacaa aaaaggcatt gaacgaatac gcccaatacc ttgacatagc
    14581 aaataaaaca acgtgcagac catggaaaat atctacatag gggtagaatt ttcaccctag
    14641 attaggtaca ataaattagg tcgatgcact gcattgacta tggcaaaatg atcggtcagg
    14701 gtgtatgtgt gtgactggtc attccctgat tcttagcgcc aactaagggt cagggagcct
    14761 ttttttattc agctgtttct atctgaattt attgtaagta atctcttatc caagtgcaag
    14821 caagaaaata caaaaaaaca ttggtatgat ttatatatat ataaataaca taaaaaaagg
    14881 aatggcttat cccgatacaa caagcattcc tttaaaaaag attcttttat ataagtgaaa
    14941 aaagcttttt tccaccaatt aaataaatct ctcatctcaa tagtttatcc attattttat
    15001 ctttttttgc gtatacctac taaatattac cgtcttcttc tcgttcttct actttgttcg
    15061 agagaatctg tactagaaaa agtagttgta tgtctacctt ttctgcctat ccgagacttt
    15121 cttttcatat atgggatata aatgattaga tacagtacag caaaaaataa agcaaatacg
    15181 caagcttccc aactacctaa cgccaattca accatcaagg tagcaacccc aacggatgct
    15241 gcataccaga taaaaatcag aaacgtttct ttttttctga ccatgcgaaa catgataaat
    15301 agactaataa gcaatagtgg caacacaaat atccaattgc ttccttccat cagccacttg
    15361 agtatatcaa gcagcgactg tgcaacagcg actaattttc ccatagtgaa cacacacctt
    15421 tttttataat taaaaaattc gcctttttat tctactatga atcttctggc ttggctttca
    15481 tttctcttat gtaatcattt tcttttatac aacttaaaaa aaaattaaac cattagcata
    15541 atattttctg aatctattca cgaaagtctt tttctatctt tcgttttcca cgactcaact
    15601 gatctagagt caaaaaacta aaacgacagt tgcgcaaatg acgcacaagc tgccgcttta
    15661 ataacaaata gcctttcatt ctcagcaggc cacttatttc cagttaactt tctgttctta
    15721 gctttttact caactggata atatatgcac ttaatgaagt cccaatttcc gaatgttgaa
    15781 gtccatattc aatatttgtc ttcatatatc ctaacttatc gcctacgtcg tatctttttc
    15841 ctttaaactc tctcgcatag accgcctctg tctggttaag agtctgaagt gcatccgtta
    15901 gctgtatctc gtttcctgct cctggttctt gagtttctaa tatctcaaat attttaggag
    15961 tcagtagata acgtccgata atggctaaat tacttggtgc ttttcccatt tcaggttttt
    16021 ctacaaaccc ttttactctg caacgaccct tttcgctatc tgttttagga tcaataattc
    16081 cgtatttaga tgtttcattt tctggtacac gcatgacggc aacagcggaa gcttgtgttt
    16141 cttcataatc catcatcaat tgttgagtca atgggatatc atctttcatc aaatcatccc
    16201 ccagcatgac gacaaacggt tcatttccta taaatgcttt tgcttgaagc acggcatccc
    16261 ccagtcctct tggatgagat tgacggatga agtgaagatt gacttgagtc gtttcttcaa
    16321 ctaaagcgag taattctgtt ttttcctttt cccgcaaatt gttttccaat tcgatatttg
    16381 catcaaagtg atcttcaatg ggtctttttt cttttcccgt tacgatcaag atgtcttcga
    16441 ttcccgaatc caatgcttct tccacaataa actggatcgt tggtttatcc acgattggaa
    16501 gcatttcttt tgccatggct tttgttgccg gcaaaaaacg tgttcctagc ccagcggcag
    16561 gaatgactgc ttttttgacc ttcacttgct
//
LOCUS       DBBGRF010000059        16504 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000059 DBBGRF010000000
VERSION     DBBGRF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.059"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..1087
                     /locus_tag="ACIZD4_002336"
     CDS             <1..1087
                     /locus_tag="ACIZD4_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5991222.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="ACIZD4_002337"
     CDS             complement(1305..2447)
                     /locus_tag="ACIZD4_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5991223.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="ACIZD4_002338"
     CDS             complement(2452..2637)
                     /locus_tag="ACIZD4_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGC5991224.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="ACIZD4_002339"
     CDS             complement(2991..3236)
                     /locus_tag="ACIZD4_002339"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991225.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="ACIZD4_002340"
     CDS             complement(3230..3631)
                     /locus_tag="ACIZD4_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC5991226.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="ACIZD4_002341"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="ACIZD4_002341"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HGC5991227.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="ACIZD4_002342"
     CDS             complement(5649..7415)
                     /locus_tag="ACIZD4_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HGC5991228.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="ACIZD4_002343"
     CDS             complement(7428..8222)
                     /locus_tag="ACIZD4_002343"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC5991229.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8232..9608)
                     /locus_tag="ACIZD4_002344"
     CDS             complement(8232..9608)
                     /locus_tag="ACIZD4_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5991230.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9728..10375)
                     /locus_tag="ACIZD4_002345"
     CDS             complement(9728..10375)
                     /locus_tag="ACIZD4_002345"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGC5991231.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="ACIZD4_002346"
     CDS             complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="ACIZD4_002346"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HGC5991232.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="ACIZD4_002347"
     CDS             complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="ACIZD4_002347"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HGC5991233.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13042..14673)
                     /locus_tag="ACIZD4_002348"
     CDS             complement(13042..14673)
                     /locus_tag="ACIZD4_002348"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HGC5991234.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14977..15648
                     /locus_tag="ACIZD4_002349"
     CDS             14977..15648
                     /locus_tag="ACIZD4_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5991235.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(15808..15999)
                     /locus_tag="ACIZD4_002350"
                     /pseudo
     CDS             complement(15808..15999)
                     /locus_tag="ACIZD4_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
BASE COUNT         5354 a         3192 c         2212 g         5746 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt ctttaaacag aaaatctttc tataaaaaac aaaaaaaaac gattaggcta
     3781 ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt aagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgacttgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttcca
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 catctggcgt tgattttaga taagtaacga ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcgtct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taataaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaattctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggtac aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagtgat aattccttta
     6421 cgatagcctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat tgaaggtaat
     6721 ccagcttcta ttaagcctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta atagaggaat tttactttct gtttgtaaga tatagttttg atcatatacc
     7201 tcatcagcag ttcctggatt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaaatc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tatatatttt tgttcaatat ctacataatc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attgaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatatcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc ttttgcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 gaatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatcga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttatg tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa tcagaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtac atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agcttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa caactattaa aaccaaaata
     8761 ggattgataa aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca
     8821 taattattca tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt
     8881 atagaaagta atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg
     8941 tattgagatt ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa
     9001 ataagtgcac atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact
     9061 atttgagcgc ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgacc
     9121 aaacttgcta aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta
     9181 atagaagtaa tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata
     9241 ctcccccata atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa
     9301 atcatagaag tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa
     9361 atccacggtt taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata
     9421 gttacatcag taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct
     9481 ccgcttatcc ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa
     9541 gtaaaatcgt ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt
     9601 ctttccatac aattctctcc cttctgttgt taagcgtttt cattctgatg aaagtacgta
     9661 ctatactctg aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt
     9721 ttttctccta ataattcttt atctcataaa acttatctat atatttacta gctactcgac
     9781 ttacttcttc aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg
     9841 caacaactcc tacttcaaac caatcttcta agttctctat acttactccg ccagtaggca
     9901 ttatatttac gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag
     9961 aacctgggaa tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa
    10021 ttgtcataca acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc
    10081 gatcaaaaga tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa
    10141 acgcatctaa aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag
    10201 caatttcttt gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa
    10261 ttccacccgc aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta
    10321 caaccgcaat gactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta
    10381 tctccttcct ttatggatac atactttgtc tagctgtact aacttacaaa gaataaattt
    10441 aagcttttat ttcaagtatt attttctact tccgatttca aaaaaattaa aataattata
    10501 cgcattacga taacaaatat tctccactat ctgactaaga tacatttcat catctggaat
    10561 tcggcctgct ttaacccact cgcttagtaa ttgacataat actcgacgaa aatactcatg
    10621 gcgaggatag cttagaaaac ttcgagaatc agtcaacata cctgtaaaat tcgacaacaa
    10681 actttgttgt gccatcgtag tcaactgttg acgcattcct tcagctgtat cattgaacca
    10741 ccaagcacat cccaattgga ttttttgaat cataccccct tggaagcttt gcattgctgt
    10801 tgctagtgga agccaatcag ttggatttaa tgaatataaa attgtttttg gtaagcaccc
    10861 actcttttca gcggtatcga acaatgctac aacattttgt gtcaaactag cttgatcccc
    10921 catcgaatca ccaccgacat ctactccaat ttgttccttt aatatacttg aattatttct
    10981 taaagcattt aaatgcattt gcatcgtcca accatatctt gtatactcag acatcaaatg
    11041 taattgaata cctgtaacaa attgtgcaat ttctgataaa tggaaatccg tttttcctgc
    11101 taaagctttt attaacagat tgtcgagtat tttttcatct gctatttcat aaaaataagt
    11161 attcaaaccg tgatctgcta atcgacagcc aatttgatga aaatgatcca ctcgttggct
    11221 caatgcttgc ttcaacccat taaagtcttt gattggtata gccgctgttt gactaagttt
    11281 taaaatatag ttcgaaaagc ctgatgattt gatactccag accttatctg gacggaaagt
    11341 aggtaatacc ttgaaagaat tatcctgttt agaaagctca gtatgatacc acaagtcatc
    11401 tgtaggatca tccgttgtac agatggcttt cacatccatc atctccaaca attctttcgg
    11461 gcgataggaa tccgtttgaa ttttttcgtt agcacgtcgc caaatttctg gtgcattctt
    11521 ctcagaaatt gtcaaatcaa tatcaaagta acgttgtaat tccaaatgag accattcaaa
    11581 aataggatta cctggcgcct tctccactgt ttttacaaaa gctaaaaatt tttcataatc
    11641 atcacctgga ccactgatca actcttcttc tataccatta gctcgcatca atcgccattt
    11701 ataatgatct ccagctcctt tatcatttaa ccatacctga gtcaaattct tgtattgctt
    11761 attttctagc aaatatgctg ggtctaaatg acaatgatag tcgataattg gttggtgttt
    11821 tgcaaattta tgaaaaagtc ttttagctat ttcattctct aataaaaagt tcttatctaa
    11881 aaacatattt aaacactcct ttccttccgt tagtttttag aagagaaaat ttttcctcta
    11941 aataaactcc cttatataat tatttactcg cccccttttc aagcgcttcc caaataccat
    12001 ttaaataaac tgcacctaga gctcggtcat ataatccata accaggtcta ccggtttctc
    12061 cccaaatcat ccgaccatga tctggacgaa tatagccatt aaatccatta tcgtacattg
    12121 tttttaatat cttatacata tctagagaac catattctga tttatgcggc gcttcgtaaa
    12181 aatcgagtcc attgtcactt aaatatttga tattacgaac atgtgcaaaa ggaatccgat
    12241 cccgttgaca aaattcagat agaatttcat agacatcatt atctggtcgt tctgcaatac
    12301 ttccagtaca taatgtaata ccattagaag gagaatccac tacattacac aaccaatcta
    12361 aatcgtcacg atttttaaca atacgaggta atccgaaaat ggaatatggt ggatcatctg
    12421 ggtgaactgc cattttaatc ccaacttctt cacatgtcgg gataattgct ttgagaaaat
    12481 atgcaaagtt ctctcgtaat ttctcttcat caacttcttt ataggcttct aataattgct
    12541 taatttgtga taaccgatga ggttcccaac ccggcaattc aaaattatta gtagaatttt
    12601 ctacttctct aataatttcc tccggatcag tagggatatt ttttgaaata taggctaacg
    12661 tagaagaccc atcatctaaa cgataatcca aatccgattt tacccaatca aatactggca
    12721 taaaattata acagataacc tcaatcccaa attctgccaa attgcgaatc gtctgtttat
    12781 aattctcaat gtattgatct cgtgttggta aaccaatttt gatatcatca tgaacattaa
    12841 cactctcaat aactttcaag gtaagtccat tggcttcgac ttcatctttt aaagatttaa
    12901 ttcgttctct cggccaaacc tctccggctg gtatatccat taatgttcca acaattcctt
    12961 tcattgctgg gatctgacga atttcttgta gtgagatttt ttcttcattt gccccatacc
    13021 atctaaaagt catttccata gttactttcc tccaacttct gttatatatt tattgattgt
    13081 tttacgaact gcttgaggac ctactagcat ttcgcaaaag attttttcag ttttctttcc
    13141 taccccaact tgatataaat ctaaaccaaa gatttcttta ttttctaaaa tttcctgtac
    13201 cgcacaatga atctttgaag gatcttgttc acctaatttc aatactgata atttatcctg
    13261 caactctacc aataacggat caggacttgg cacaaaattt tccccttgat catcgactgc
    13321 cagtaaataa cgtaaccaag cagcaatagc gataggaata aatgttagat tttctgcatt
    13381 tccgtctttt tcgacatact ttttaattgt ttcaccatag cgaatcgcta ctttttgaga
    13441 agtatctgtt gcaattcgtt gtggtgtatc tggaatatag ggattaggca aacgtttatt
    13501 aattacttca tcaataaatt gttttggatc aataatgcct ggattttcaa ctactggtaa
    13561 accttctaaa taacctattc ctttgattaa accaaccaaa tcatcatcct gcatctctgc
    13621 tgaaattgat tgatatccta gcagacaacc tgttactgcc aaagcagtat gaagtggatt
    13681 caagcttgtc gtaaccttca tgatgtctgc tttatcaacc gtctctctat ctgtcataat
    13741 cacaccagcc ttttccaatt taggccggcc atttggaaaa ctatcttcaa taactaaata
    13801 atgaactacc tcagtattag tgaaagcagc aatattggta tgtttttttg tgtgaatgat
    13861 atctaaatcc tcgagcccca tcatcaatag atcttccttt acattctctg aaggatttgg
    13921 cgtaattcga tcaatcatac tccaaggaaa agtcactttt tctttatcct ttaaataagc
    13981 aataaatttt tcagaaacat atccttcttt ttgccaagct tctgcaatcg taaaaatact
    14041 atcttgaaaa cgttgaccat tctgtgagaa attatcagta gaaaccatcg caatcggcaa
    14101 ctctccagca ttaaatctgc tatataacaa ggatgttaca atactcatcg tatgttgagg
    14161 attgctaggt ccagatttga tatcagcttt gactaccgaa aagaattgcc ctttagaatc
    14221 ttttaaactg taaccttttt cagtaatagt aaacgttgta aactgtaatt taggatcttc
    14281 aaaatattta accactcttt gatagtccgc tatattcttc ggattgcaat ataaactatc
    14341 agccgttact gccaaaagtc tttttttgag ttcaccatct ccactcataa caatttccaa
    14401 aatgtcattg ttatagtcat gataagcttt ttccactact tcttcatcaa atgtttcaca
    14461 cacaactact cctgtttcta attcattttg atctgctaag cattgagcaa tttctgcatg
    14521 aaatcctcga taaagatttc ctccaccaaa atgaagccat actggatgtt gctggccttc
    14581 ttgcttaact tctttgacat caaaacacgg cagtagaatc tgcatttcat tgaattcttc
    14641 gatagaattt tgccaatttt taatcgaaac cataattaac ctcctcaaac tgatatgtta
    14701 gttttgatac attttatatt ttaaaaccca ttgtaaccgt tgtcaatata aaaagggaat
    14761 aaacttgctt ttttctacca tatcagaatg attgtatttt ttattcagaa aaataaaata
    14821 ctccttcttt ttggactgat tttatcgaaa cttatttttt ctttttttca tgtattcttt
    14881 tatttttata actagtgtat tacttcaaaa tttgatatta tatggcatga acagaattaa
    14941 aatatcagtt aaaataaaag ttaaggagca ttgtgtatga caattaaaac tagtctccaa
    15001 aatcaagctt accaatctat tcgccgacaa attatctatg ctgacttaga acctggaaaa
    15061 aaagtatcag aaaaaaaatt agaagaaaca ctttctattg gtcgtacacc aatacgtgaa
    15121 gcactgattc aactccgaca acaaggtctt gttgatacaa ttcctcaaag cggaaattat
    15181 atctcattaa ttgatttaga ttcggccaaa aatgctcgat ttgtcagaga acatttggaa
    15241 cgacaaatta tgttagagtg ttgtgccaaa atgaataacc aaaaaaaacg gattttagaa
    15301 actataattt cagaacaaga aaaagctgtt agtcaaaaaa atgctcgtag tttttttcat
    15361 aatgataatt tattccataa agcttgtttt gaaattgcag agcgagaaga agtatggcaa
    15421 tggttagaaa ataacaatac acacttagaa cgatttcgat ggctacgagt aaaaacggaa
    15481 ggattaaagt gggaaaaaat tatggaacaa cattatcaac tatttgaggc attaacaaaa
    15541 caagatccag aagaagctaa ctttctaaca tcgttgcatc ttcatttaat gcttaatgag
    15601 caaaatattg ttttagctac tcatccaaaa tatttcaaaa atatataact tttaactctt
    15661 tttaaattaa atggttgttc tgatcagaaa aatatcgctt gttttcttat tatgtaatat
    15721 atttcataaa ctattctgca taacaactat tgtttgtact ttttacattg gataactaat
    15781 tatgactgct gataactttt gatattaaac tagtatctcc aatacaaata aaaaatagat
    15841 atcttgttca tcaaaattag ttcgtggata cttaccttca tttacatcat tcagcggttt
    15901 cccattttct tttattctat tatttcattt tctaatagac ttggcttcat ttcgcaatac
    15961 tttttttcaa taggcatcaa attggtgttg tttagatatt tagttgtagt tttgtgacat
    16021 gataagtatg ctcctttttc tcttttccac taatacaacg atcaaagggt gcttttttca
    16081 aaaaactaga aaaatcaaaa taagattcgt attttgattc tatatatcct gtttcaacta
    16141 catcttatat ttcacaatag aataaatagc cttttgcata gctgcttaac ttataagaaa
    16201 ttgcaattta cttcttcaaa gtgaaaacga atatgagtaa aataaaatta ttcttcttac
    16261 agataattaa aaatagcgcg taacaaaaat cggcattcaa tcacataatt aggattgatg
    16321 ccgattactt atattctacg tatagtttta gtattcttat tttttatcac cagtaaccaa
    16381 ttgagaacag ccctaaagca gaatagtctt ttatctcaaa acgcttaatt tcaggcttag
    16441 gaatatgaat aatcttttga gtatattctt tctcttttaa tcttactgaa gaaataccac
    16501 tgcc
//
LOCUS       DBBGRF010000060        15860 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000060 DBBGRF010000000
VERSION     DBBGRF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.060"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(12..482)
                     /locus_tag="ACIZD4_002351"
     CDS             complement(12..482)
                     /locus_tag="ACIZD4_002351"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGC5991236.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="ACIZD4_002352"
     CDS             complement(641..1099)
                     /locus_tag="ACIZD4_002352"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGC5991237.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="ACIZD4_002353"
     CDS             complement(1270..2415)
                     /locus_tag="ACIZD4_002353"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGC5991238.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="ACIZD4_002354"
     CDS             complement(2428..3345)
                     /locus_tag="ACIZD4_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HGC5991239.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="ACIZD4_002355"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="ACIZD4_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGC5991240.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4437..4607
                     /locus_tag="ACIZD4_002356"
     CDS             4437..4607
                     /locus_tag="ACIZD4_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991241.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4822..6081
                     /gene="lysA"
                     /locus_tag="ACIZD4_002357"
     CDS             4822..6081
                     /gene="lysA"
                     /locus_tag="ACIZD4_002357"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGC5991242.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6068..6868
                     /gene="dapF"
                     /locus_tag="ACIZD4_002358"
     CDS             6068..6868
                     /gene="dapF"
                     /locus_tag="ACIZD4_002358"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HGC5991243.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6871..7752
                     /gene="dapA"
                     /locus_tag="ACIZD4_002359"
     CDS             6871..7752
                     /gene="dapA"
                     /locus_tag="ACIZD4_002359"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGC5991244.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7749..8465
                     /gene="dapB"
                     /locus_tag="ACIZD4_002360"
     CDS             7749..8465
                     /gene="dapB"
                     /locus_tag="ACIZD4_002360"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGC5991245.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8471..9166
                     /gene="dapD"
                     /locus_tag="ACIZD4_002361"
     CDS             8471..9166
                     /gene="dapD"
                     /locus_tag="ACIZD4_002361"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGC5991246.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9182..10183
                     /locus_tag="ACIZD4_002362"
     CDS             9182..10183
                     /locus_tag="ACIZD4_002362"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGC5991247.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10180..11541
                     /locus_tag="ACIZD4_002363"
     CDS             10180..11541
                     /locus_tag="ACIZD4_002363"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGC5991248.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11501..12652
                     /locus_tag="ACIZD4_002364"
     CDS             11501..12652
                     /locus_tag="ACIZD4_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGC5991249.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12627..13796
                     /locus_tag="ACIZD4_002365"
     CDS             12627..13796
                     /locus_tag="ACIZD4_002365"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGC5991250.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13971..15350
                     /locus_tag="ACIZD4_002366"
     CDS             13971..15350
                     /locus_tag="ACIZD4_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC5991251.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15631..15860
                     /locus_tag="ACIZD4_002367"
                     /pseudo
     CDS             15631..15860
                     /locus_tag="ACIZD4_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5185 a         2799 c         3378 g         4498 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa attttgttta
     4741 atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa acggaaaaaa
     4801 agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac agcaagcaca
     4861 ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat gagacaaacg
     4921 atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt gctttacgcc
     4981 tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg attcgggcta
     5041 gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc tagagatact
     5101 atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact tgaaaatgat
     5161 ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga attaagccaa
     5221 cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga agcacatact
     5281 catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa
     5341 gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt agaaggattt
     5401 catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga aatcgacaaa
     5461 ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg cggagggttt
     5521 gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact aaaaaaactg
     5581 attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca attactgatc
     5641 gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat tggtttcatc
     5701 aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga taatatccgt
     5761 ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc ggaagaaaaa
     5821 acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa
     5881 gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac gggagcttat
     5941 ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt ttttgtcaat
     6001 aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact aaggggggaa
     6061 gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct tattagatta
     6121 cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag aaaaatatga
     6181 tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt acaacaaaga
     6241 tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat acgtaaatga
     6301 tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca caagaaaaat
     6361 tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc cagatgattc
     6421 tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa tagagatcaa
     6481 tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg ttgtttttgt
     6541 tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc atcatccttt
     6601 gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag aattgatcgt
     6661 ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt gctgtgcctc
     6721 ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg ttcacttgga
     6781 acaaggagac ttgatgatct ctggtgagga tgcgatacaa atggctggcc cagcagttca
     6841 tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt ggcgctgatc
     6901 acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt gatccaattc
     6961 catttagatg aacaaacaga tggattatta gttttaggta caacaggaga atcttctacg
     7021 ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt ggctggccgt
     7081 gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga aaaagcgaag
     7141 cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta caacaaaaca
     7201 agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc gattccgctt
     7261 attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt attagtaaat
     7321 ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat ggcttatgtg
     7381 atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa tgatgatttg
     7441 atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa
     7501 cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca gcaagcaaaa
     7561 gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac caatcctatt
     7621 cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg cctgccttta
     7681 gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg
     7741 gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga gtcgaagaag
     7801 ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa gaagcaacta
     7861 cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca gataatttag
     7921 agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc acgacaggtt
     7981 atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct gtgatgtata
     8041 gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa gcagctgcaa
     8101 tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa aaagatgcac
     8161 catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg
     8221 tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac agtattcgtg
     8281 caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa atatttacga
     8341 tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa gcagcggact
     8401 ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg gacaaagggg
     8461 tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat ctaaaaagac
     8521 gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt
     8581 tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc cggttttaga
     8641 agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat acagcgcagt
     8701 tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga
     8761 tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca atattggtgc
     8821 agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac gagcgacagt
     8881 gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc
     8941 ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag tgattgttga
     9001 aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt tagaagatgt
     9061 ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca
     9121 gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga gatggagaaa
     9181 aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct
     9241 caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag cttcaaaacg
     9301 ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg aattgacaga
     9361 aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg tatccaaaga
     9421 gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct cagcatggcg
     9481 ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact atacattgaa
     9541 tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc ttaaagcttt
     9601 acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag tttctggttc
     9661 cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac cagttttgta
     9721 tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg aaaatgggta
     9781 tacaaaagaa gaacagaaaa tgataaatga gacccgtaag attctgcatc agcctgcttt
     9841 gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc
     9901 agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca gccagtttcc
     9961 agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca ttcttgctag
    10021 aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag agaacggatt
    10081 gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg ccgtacagat
    10141 tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac gctgaaagta
    10201 gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt
    10261 gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca
    10321 gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca gcatcatgtt
    10381 gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag agatgttctt
    10441 gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact ggaagacgaa
    10501 aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca actgatggct
    10561 gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga ctatgatggg
    10621 aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag atatccgaaa
    10681 atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt attgggccgt
    10741 gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga aagttatgag
    10801 aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga tcatcctaaa
    10861 atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg ggctaacgtt
    10921 cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca aataaaaaat
    10981 accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga aaaggaaaat
    11041 ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt caaacgtcat
    11101 atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa acatgagata
    11161 tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc agcagaagcg
    11221 attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg cgtggaagaa
    11281 atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca taaagaattg
    11341 attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg cacatcgatc
    11401 ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa tcaatatgaa
    11461 acagtagtga agggtatcta tgaagggatg gtgaatacgg atgctgaaag aatatcgaat
    11521 ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa aatatttata
    11581 tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag gactactcct
    11641 ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg atgcactgcc
    11701 agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata tgcatgcatg
    11761 tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa ctaaacacat
    11821 tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa tttccggtgg
    11881 cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag caatatttgg
    11941 ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag gacctttgat
    12001 ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata ttgcttctag
    12061 tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg tttatgattt
    12121 tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa tccaaggtgg
    12181 aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc gttcttacag
    12241 ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac agtttcactc
    12301 tacagctact atttcttttc gctataatga cggctatcca gctgtaatca accatagagg
    12361 cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc cagttcttca
    12421 agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct ttttaggtgt
    12481 cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg ttttagaaaa
    12541 tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa aaatcgatag
    12601 cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt agtcctaggc
    12661 tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg tcgataccag
    12721 atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat gtcaagcaag
    12781 caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga ggattagagg
    12841 aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact tatgatccgc
    12901 aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg
    12961 ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga tatcagccat
    13021 tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca gggtttgtct
    13081 gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc aaagcagtca
    13141 ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa
    13201 tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta tatgctgaat
    13261 tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa acaatcgtga
    13321 taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt atttttgctc
    13381 aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact gccgctacaa
    13441 cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat agcgagaata
    13501 tgaaagagca atatcaaaca cgaagagact atctggtcca gcaattggcg cctttaggat
    13561 ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca gctgccattc
    13621 aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc
    13681 caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat gctagcagca
    13741 tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa cagtgattca
    13801 tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg agacgattgt
    13861 tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg taatgttaag
    13921 tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca atggaaaaaa
    13981 tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg gaactattga
    14041 cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat atttccttca
    14101 tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat gatgtacgta
    14161 atttcagacc agaaaacttt ccgcaatcca atgttcatat tttaaataat cacgaagtaa
    14221 aaacgatcga tgccgataaa aaaacagtaa cggttactag cgcatcagat aacgaaacaa
    14281 aagaatatcc ttatgacaaa ttgattttga gttctggtgt caaaccaaac aatctgccag
    14341 taccaggagc agatctagaa aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa
    14401 tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca
    14461 ttgggatcga agcagcagaa gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg
    14521 tgatcgatag acctttaggc acttatttag atgctgagat gacagatatt ttagaacaac
    14581 acctaaatga aaacggtatt gaagttttga caaatgcaaa aatcgaagct tttactggta
    14641 acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat cccagcagat ctagtcattc
    14701 aagctgccgg tgtgaaggca aatacagaat ggttaaaagg gatcgtcgac ttagatgaac
    14761 gtggctggat ccaaacaaat gaatacttgc aaacgaatct tccagatgtg tatgcagtag
    14821 gagatgctac acttgcttat tctatcccag cacgcaaaaa aatgccgatc gctttagcga
    14881 ctgttgcacg tagagaagca cgttatgtag taaaacatct ttttgaagaa gtaccaaaca
    14941 aaccgttcgg cggagtcgta ggttcctctg cattaagtgt ctttgactat cattttgcag
    15001 caagcggatt gaatagcttt acagcagcaa aagcaggagt agatgtacga gtgtcttatt
    15061 atgaagatac gttacgacca aaatatgtac cagaagaaca aggaaatcca aaagtgtcca
    15121 tccaattatt ctcggatcca atgacccatc aattgctagg aggagcagta ttatctacct
    15181 atgatgttac aggtcaagga aatgtattgg cactagcgat ccaaaacaaa ctgactttag
    15241 aagaactagc agaagctgac ttcttcttcc agccaggctt tgaccgacaa tggagcatgt
    15301 tgaatctagc cgctcaacaa gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa
    15361 tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag taataagaac agccaagtaa
    15421 aaacagcttc ttatgttttt aacttggctg gacttattac cgcagatgca agcttttgaa
    15481 caccgtttat tttcaaaaaa gggactgtga cacgatttgt gtaccgaccc ccaaaagtta
    15541 gaccaaaaaa tctaactttt ggaggtcggt attttttatg gttaaatata cttttgaact
    15601 taaattaaag atcgttcatg attatttgga tggcaaaggc gattggaccg taaaaatcca
    15661 gatcaagaga ttgaagcgga aatgcttaaa attcgggaga agcacaagga ttatggctgt
    15721 ttacggatga ccaatgaact aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag
    15781 cgcttgatca agaagctagg aataaaagta acggcataca cgcgtaaatc acgtcgctac
    15841 aattcttatc gaggaaaagt
//
LOCUS       DBBGRF010000061        15675 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000061 DBBGRF010000000
VERSION     DBBGRF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.061"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..338
                     /locus_tag="ACIZD4_002368"
     CDS             <1..338
                     /locus_tag="ACIZD4_002368"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991252.1"
                     /translation="CKAIFEGQKGGKNTFTFDISQIEHSVYYMSVLLIYSCFEGIRYI
                     IEYSGFVYVHYTEKLLVSKKSEDKHGKLPWKSEICEKSLYIKGFFFFLYHSFKPFLAV
                     LDHFSIIFP"
     gene            578..1240
                     /locus_tag="ACIZD4_002369"
     CDS             578..1240
                     /locus_tag="ACIZD4_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991253.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            1319..4546
                     /gene="fss3"
                     /locus_tag="ACIZD4_002370"
     CDS             1319..4546
                     /gene="fss3"
                     /locus_tag="ACIZD4_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HGC5991254.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITDAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            4660..4974
                     /locus_tag="ACIZD4_002371"
     CDS             4660..4974
                     /locus_tag="ACIZD4_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC5991255.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            4987..5361
                     /locus_tag="ACIZD4_002372"
     CDS             4987..5361
                     /locus_tag="ACIZD4_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HGC5991256.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            5371..5715
                     /locus_tag="ACIZD4_002373"
     CDS             5371..5715
                     /locus_tag="ACIZD4_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGC5991257.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            5786..7138
                     /locus_tag="ACIZD4_002374"
     CDS             5786..7138
                     /locus_tag="ACIZD4_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGC5991258.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFWVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            7198..8340
                     /locus_tag="ACIZD4_002375"
     CDS             7198..8340
                     /locus_tag="ACIZD4_002375"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HGC5991259.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            8365..8619
                     /locus_tag="ACIZD4_002376"
     CDS             8365..8619
                     /locus_tag="ACIZD4_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991260.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            8875..10059
                     /gene="mobT"
                     /locus_tag="ACIZD4_002377"
     CDS             8875..10059
                     /gene="mobT"
                     /locus_tag="ACIZD4_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HGC5991261.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            10056..10193
                     /locus_tag="ACIZD4_002378"
     CDS             10056..10193
                     /locus_tag="ACIZD4_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HGC5991262.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
     gene            10198..10419
                     /locus_tag="ACIZD4_002379"
     CDS             10198..10419
                     /locus_tag="ACIZD4_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991263.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            10432..10932
                     /locus_tag="ACIZD4_002380"
     CDS             10432..10932
                     /locus_tag="ACIZD4_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HGC5991264.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            11029..12876
                     /locus_tag="ACIZD4_002381"
     CDS             11029..12876
                     /locus_tag="ACIZD4_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HGC5991265.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            12879..13775
                     /locus_tag="ACIZD4_002382"
     CDS             12879..13775
                     /locus_tag="ACIZD4_002382"
                     /inference="COORDINATES: protein motif:HMM:NF024700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5991266.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNFYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            13825..14214
                     /locus_tag="ACIZD4_002383"
     CDS             13825..14214
                     /locus_tag="ACIZD4_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC5991267.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            14201..>15675
                     /locus_tag="ACIZD4_002384"
     CDS             14201..>15675
                     /locus_tag="ACIZD4_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5991268.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPLSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGG"
BASE COUNT         5273 a         2519 c         3462 g         4421 t
ORIGIN      
        1 gttgtaaagc gatatttgag gggcaaaaag ggggcaaaaa tacgtttacc tttgatatat
       61 ctcagattga acatagtgtt tattatatgt cggtattgtt gatttatagc tgttttgagg
      121 gtattagata cataatagaa tatagtggtt ttgtttacgt gcattacacg gaaaagctgc
      181 tcgtatcaaa gaaatcagaa gataaacacg gaaaacttcc ttggaaatct gaaatttgtg
      241 aaaagtcctt gtatatcaag ggctttttct tttttctcta tcacagtttt aagccatttt
      301 tggctgtttt ggaccatttt tcaatcatat tcccttaaaa attgtcctag attgtccgac
      361 attgactatc agtgtcgtca aaatagggca aaatttagta gtcagcttga cgacaaatat
      421 aatacgaaaa ataccaaaac atttaccgaa tttagcaact tttgaaccca agtttctcaa
      481 agggtcagct attagcaaaa aagacaaaac atgtactttt ctactaaaaa gttgatgtga
      541 taggcttcta tctaaataac tattaggagt ttttatcgtg aagcaaaatg atggacgtat
      601 catttggaaa aatcaaagtg agttaaaact gattttaaca attaatgaat tcatcgaaaa
      661 acacggaatt acatctagcc gtcaatacca gaaaaagcta tcagaaaatc caaattctgc
      721 accaagtatg tggttcatta acaaaaaata tggatcatgg gagaatttat tgattagtat
      781 aggacgagaa aatactgggt atggaaaatg ggctagaatg tcagaacaag aattattgga
      841 aatagtagaa gcctttatta agtgcgagaa gataacctct caacgaatgt acgaacaaaa
      901 atcagtaggg aagaatattc cttcacttag taccattaaa aagatgttag gagatatacg
      961 tccacttttt aaagaaaaaa atgatggatc tcgatttact gatttcgaac tgctgttaga
     1021 actaaaaaat gaaataatcc gattaaaact acaggatgat ttatcaatga caaagtttcg
     1081 aaaactagtt caatccccaa aactaccatc agttgataca attatgaaaa gaacgaacaa
     1141 aaattgggag gaattgatgg cagagattgg atttgattat cgaagaatca aaatttataa
     1201 gcagagaaac aacctatcca agacaaagaa aactaaatag tatcactcta aatcagacgt
     1261 tcaaaattaa aatttggacg tcttttttat tacccaaaaa cgaaaggaga tttattttat
     1321 gaaaaagcca agatttaaga attggcgttt gctcgcaaca ctgagtctat tatgccaaac
     1381 aattggtgga tcgcttggcc caacgattgc ctttgctgat gaaattactc atccacaaac
     1441 ggtaactgtg gaattggatt tggctcacca gtatgctgtc gaaggtacat ttagcgatgg
     1501 tcgtcccatg tcagaagtta ccgttccgca ctatgcagtt tacaatggtg tgaagcaaga
     1561 tattttctgt attgagccag gggtgccgat ttacaatgag ttcactcctg gttatgagaa
     1621 aaatccattg cctgatatgt cggagaaagc gaaattagtt tccgttttat ggaaggaagc
     1681 tggtacggat gtggatacac atattgtggc ccagaagatg atttggcaag aagttaatgg
     1741 ctacacgctt cactcaatta aacgttctga tggtagtgca gtaaatatcg cagccattga
     1801 gtcaaaaatc aatcaagcca ttgcggatta tcaaaagaaa ccaagcttcc ataactccac
     1861 agtgaaaacc gtgttaggtc aatcgactac tgtgacagat acgaacggct tgaatttatc
     1921 ggagtttgat gaagttgtcg agaatatcgc aaatattgat tatcgtgtga acggcaatca
     1981 actagtgatt actccaaatg ccaattcaaa agagagtggt gaattaaccc taaagaagtc
     2041 agctaataca ggaacaccgg tagcttataa aatggctggt caacaaactt tgatggcggg
     2101 ggcaattgat aagcccaata cctacacaat caaaattgat gtggaaactg agggttcttt
     2161 gaagattaaa aaagtcgata aagaaacagg aaatgttgta ccgggaaccg ttttccattt
     2221 agactttgga aaaacattac ctgcaaaaga cgtgaccacc gataaagaag gcattgcgac
     2281 attggatgag attcctcatg gcgcgaaagt aaccattact gaaaaatcag tgccagctcc
     2341 ttatacgatt gacactacac caatcaccgc aaccattaaa tctggtgaga ctatttctgt
     2401 gacttcaaaa aatactcgcg aaaaaggtca aatcattttg aataaaatgg gggtggaaac
     2461 aggaactgat ctttggaacg acaaatactc attagccgga aatacgtttg ccattcgcaa
     2521 agacagtcca accggtgaaa ttgtccaaga aatgaccacg gatgaaaaag gtcatgcgga
     2581 aacaccaaaa gagattgcca atgcgttgga attgggaacc tattatgtga ccgaaaccaa
     2641 agctagtaat ggctttgtga atacctttaa accagtaaaa gtcgaattga actatgtcaa
     2701 tcaaaccgtg gctcttgtta ccagtaacgt aaaagggcaa aaccaagaaa tcactggtga
     2761 aaccactttg acaaaagaag acaaagatac cggtaatgaa actcaaggta aagctgagtt
     2821 taaaggagct gaatatactc tctttactgc aaaagatggt caagcggtca aatggagtga
     2881 ggcttttaaa ccagagttag tgaagggaac gaaagcttct gatgaaacgg tgactttgac
     2941 tttagatgaa aagaatcaag ttgctgttaa acacttagcg attaatgagt attactggca
     3001 agaaaccaaa gcacctgaag gatatacctt ggatgaaaca aagtaccctg tttccatcaa
     3061 aaaggtggat gataacgaaa aaaatgccgt gattacccga gatgttacgg caaaagaaca
     3121 agtcattcgc tttggctttg atttctttaa atttgctgga tcagctgctg ggactgccga
     3181 aactggcttc aatgatctga cctttaaagt atcgccattg gaaggaacca gtgagattac
     3241 agatgccgaa gatgaagcaa ttacagctta taacgagcaa ctaggttttg atggctatgg
     3301 caagtttgaa aatcttcctt atggggatta tttacttgaa gaagtagagg ctccagaagg
     3361 atttcaaaaa attacgccat tagaaatccg ttctactttt aaagaaaata aagcggatta
     3421 cactaagagt gaatacattt ttacgattac cgaaaaagga caaaaacaac caattaaaac
     3481 ggtgaccgtt ccttacgaga aactgacgaa taaagcattt tctgttagct tgaatcgttt
     3541 gatgctctat gatttacctg aagaagaaga tagcttaact tctcttggga cttggaaaga
     3601 cggaggcaaa gaattgacag accttgattc taccgagcta gttgataaat tgagctataa
     3661 cttgcatgaa atcaaagaag actggtatgt ggtagcgcaa gccattgatg tggaagcgac
     3721 aaaagctgcc caagaaaaag atgaaaaagc caaaccagtg gtaattgccg aaacaaccgc
     3781 aacgttggcg aataaagaga aaacaggaac ttggaaaatt ttgcataaat taaccgcaga
     3841 acaagttttg gataaaacca tcgtcttatt caactatgtg tatgaaaaca agaaacccta
     3901 tgaagcaggt gatgatccag tagcgaaaga tgctagcttg aacaatcaag cccaaactgt
     3961 caattgtacg gtggaacgcc atgtttccat ccaaacaaaa gcccacctag aagatggttc
     4021 gcaaaccttt actcatgggg atgtggtgga tatgttcgat gatgtgtcga ttacccatga
     4081 tgtactggat ggctcaaaag aagcttttga aacaattctg tatgcattac ttccggataa
     4141 tacgaccaaa gaaatttgga aatctggcaa aattgattat gaagtgaatg acaaagaatt
     4201 cactaaaacc gtacttgcgg aaaaagtgga cacaagtaaa tatccagaag gtacaagttt
     4261 taccttcaaa gaaattaact atggcaaaga cggaaacatc aatgggaaac acaatgagga
     4321 tctaaaagaa aaaactcaaa ctttaacacc taaaaaagtt ccgacaacac caagtgcacc
     4381 agaacaaccg gaaataccaa ctgttccaag tgactctcaa gaatctagtc ctacagtaaa
     4441 gacattccca caaacagggg agaaaaattc taatgttctg ctgtttattg ggtttacctt
     4501 gatctttgcg actgctgggt attatttctg gaatcgccga aactaaggtg atgtgatgaa
     4561 acaactaaat aggaaaaacc aacgtgcgcg accgcctcct aaaaaaagtg gtcgcgctat
     4621 ttttgtatcc aaaactaaaa atgaaaagag gaaaagaaga tggaattgaa atttgttgtg
     4681 ccagatatgg ccgaaacctt tggaaagata aggtatgccg gcgaaggcga agttttaact
     4741 gaaggatatg ggcggaatac tacagtaatt ggtcgtagtt atcatttgta ttccagtaag
     4801 caacgagccg atgatattga agtggtggta gctgcggaag ccggcgaaaa ggattttgat
     4861 caagatcaac cactaaaagc cgtgaatccc catttggttg ccaaaggcta tgagattgag
     4921 aatcgtgggt ttaccgacta cgtgttgtat gtcgatgatt tagtgaaagc ataggaggaa
     4981 aagaagatga gattaacaga aggtattgtt gtagattcag gactaacgtt tgggaaatta
     5041 cgattttccg cattacgccg agaagtacgg aagcaaaatg aggatggaac ggttagtaac
     5101 gaggtaaaag aacggactta taatttgaaa tcctctgcgc aaggtcgaat gatccaagtt
     5161 agtatcccag caaatgtacc cttacgcgag tttgcctatg acgcagaggt agagttggtc
     5221 aatccaatca tggatacggt cgccaattat gttttccgag aaggaactac tgtcaattgg
     5281 ttcattaagg ccgatgattt agtcttgaaa cgacaaccag atcagggaaa ttctacaaac
     5341 caaaatgaag gaaagaaata ggtgaagcgt atggaaatta atgttgaaca tattttagat
     5401 tgtctcgatc aatatggaaa aggtgagcta acggaggaac aactcactaa agcattaacc
     5461 tatgatgaaa aaatgtttct gattatgcat caagggttac tggaagtagg taacgatgcc
     5521 gaagaagatt ttgatgtact gaattggtta ggggaagaag agtccttctt tatggttatc
     5581 gaagtaaatg aaagtctatg tcgagaagcc gaaaccgtat tggaagaaat tggtgtggaa
     5641 atgccggatg ccattgaagt ttttttaaag caactagtgg aaacgaaaca actccctata
     5701 gcagtaaatg actagcataa ctgcttgaaa ttggatcaat gaaatcctat gaagcttttt
     5761 tcgattggag gtggaaacca taaaaatgta caaagggcat cgtatacggg caggagatca
     5821 gcacttggtt tatcactttg ttcttggctg gctactcgct ctgttcatcg gttggatgag
     5881 cgtcttttat tttcaagagc ttagacaatt tgatatttct aagctatcac tttctactat
     5941 agaaatcgtt cgttctataa aagatttaat ctatttgcta ggaagtctcg ttctttcagg
     6001 aagcacgatg ttgctttata tacacttttt tcaggatcat tggcgcagtt tgtggcatcg
     6061 acaaaagcta gcccggatga ttctagaaaa tcattggtac gaagtaaaac aaactcagag
     6121 tgaaggattt ttcaaagacc tcaatagtag tcgaaccaaa gagacaatca gttacttccc
     6181 caaaatctat taccgtatga aggatggttt actttctatt cgcgttcaaa tttcactggg
     6241 aaaatatcaa gatcagcttt taaagctgga aaagaagtta gaaagtggtc tatattgtga
     6301 actagtagaa aaggaactca aagactccta tgtggagtac actttactgt atgatataat
     6361 tgccaatcga attgggatag acgaagtagt ggcagaaagt ggggctttgc gattgatgaa
     6421 aaatcaagta tgggcttatg attctttacc tcatatgtta atcgctggcg gcacaggtgg
     6481 tgggaagact tactttttac tcactatcat cgaggcttta ttaaaatctg atgccgagct
     6541 ttttgttctt gatcccaaaa atgcggactt agccgattta ggtacggtaa tgcctcatgt
     6601 ctattcccaa aaggaggaaa tttctgcttg tgtggaagat ttctatgagc gcatgatgac
     6661 tcgtagcaag gcaatgaaag aaatgcccaa ctacaaaaca ggagagaatt atgcgtttct
     6721 tggacttcca ccaaactttt taatctttga tgaatacgtg gtttatatgg aaatgttaac
     6781 gacgaaggaa agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt taggtcgtca
     6841 atctggtttc tttctgattc tagcttgtca aagaccggat gcgaaatatt taggagacgg
     6901 gattcgcgat caatttaatt tctgggtggc tttgggtcgt atgagtgaac tgggatattc
     6961 catgatgttt ggcgaggttg ataaaaaatt ctttatgaag cgtatcaaag gtcgaggcta
     7021 tgtagatacg ggagggagtg tgattagtga gttttatacg ccacttgtac caaaaggata
     7081 tgatttctta agggaaatta gcgacattgg tggattaaac gttaatacgg aaggataaaa
     7141 taatagtatg tagcctagga gtgtcaagaa tcctgggctt tttttacgag gtgatttatg
     7201 acatttttag atttattcgc tgggattggt ggcttttgct taggtatgga acaagcgggt
     7261 caccagtgta tcggcttttg tgaaattgat gattttgctc gccagagtta taaggcaatc
     7321 catgatacaa gtaaggaggt ggaaatgcat gacatcacaa gtgtatcaga cgagtttatt
     7381 caatctctcg gaccagtgga tatcctttgc ggtggatttc cgtgccaagc tttttcaatt
     7441 gcgggaaagc ggcaaggatt ttccgatact cgaggtactt tattctttga aatcgctcgg
     7501 ttcgccgcta ttctccaacc taagttttta ttccttgaga acgtccgggg attactcaat
     7561 cacgaaggag gggctacgtt cgagacgatc ctccgaacgc tggatggatt ggggtatgat
     7621 gtggaatggc aagtgcttaa ctcaaaggcc tacgttcccc aaaaccgtga gcggatcttc
     7681 cttatcggac attctcgaga cgcatgtacc gaacaagtat ttcctatcat tggatcgtct
     7741 ccaacatctg atcaaaacat cagaaactta ttaaatatca acccttccaa tcgaggaatg
     7801 gggggacaag tctatgggtc agatgacgta gcgcctacct tgaccggtga tgaaggaatc
     7861 aaaatcgcat tgccggtaga tgatggaatt tctgtagcgg gtatgttact gggaaatttt
     7921 gaacaaggca atcgggttta tgagataact ggaacagcgc ctactttgtc aacgaaacaa
     7981 ggcggaacga agatcatgct tcggaaaaac gaaacagaat atcaagaggt gaagccaggg
     8041 aacagtgtga acctggcttt tcctaattcc acaagtcgtc gaggccgtct gggaaaacaa
     8101 agtgtgcata ccttattaac aggagaccaa caagcagtcg tcacggatca gtatcaaatt
     8161 cgaaagttaa cacctaggga gtgctggcgg cttcagggct ttccggactg ggcttttgat
     8221 cgagcttctc aagtcaattc agatagtcag ttgtataagc aggctggaaa ttctgtaaca
     8281 gttccggtca tttttgatat tgctagaaga ttaaaggagg taaaaacaga tgatttatga
     8341 tgagttgatt ggggaatcta ctgggtgatt ggcaagattc agtcagatcc ggaattggaa
     8401 gaagaactgt accggctcaa ttttgatatt cgcaaaaacg gggtgaaagt ccctgatgat
     8461 ccgtatgtaa ttgatgagga aacggatgct cgaatggagc tgaatcaagt catcagtgaa
     8521 ttggaacgaa ttgcggactt tgctaaagaa cctgatatcc gccaatactt gtttgagata
     8581 aaagcagagt tggaaattga gggtattacc gcggagtaac ggccaaataa accactgata
     8641 ggcactgacc gcgggggatt tgcgaagcag aaatcctccg tggtgctgtg cctgtttatg
     8701 gacggcgtta gccggccatg atgtctcacc ccccgtatct aacagggggg tacaaaaaca
     8761 caaaaaataa gcaagcaacg ataaggaatg gctgtcctat caaggataat aagcaatttg
     8821 tgtagatgtt aactgatttg aaaaagttaa caccttaaat ttggaggtga gaacttggca
     8881 caaaggaatt tagattatcg gctattaaaa gaccggcgta atgaatatgg cgtttcacaa
     8941 aataaattag ctacgacttg tggacttagt cgcccgtact taaatcagat agaaaatggt
     9001 ggcgtaaccg catcgacaaa aaccatgagg aaaatttttg accaactgga aagtttcaat
     9061 cccgagttac ctttaacgtt actgtttgac tatgtaagga ttcgctttcc cacaacggat
     9121 gcgaggaaaa tcattcaaga gattctccat ttgaaatttg attatatgct ccacgaagat
     9181 tacgcctttt actcctatca agaacaatat gttatgggag atattgtggt gatgttgtca
     9241 catgaagaag ataaaggcgt ccttttagaa ttaaagggtc gtggttgtcg gcagtttgaa
     9301 acttttttac tcgcccaaaa gcgtagctgg tatgactttt tcgaagattg tctaaaagcc
     9361 ggtggcgtga tgaaacgctt agacctggca atcaatgatc gagttggcct gttagatatt
     9421 cctgatttaa cgaaaaaatg tcagaaggaa gaatgtatct ccttgtttcg taccttcaaa
     9481 agctatcgtt ccggggaact gttgaaacct gatgataaag atggtatggg caatactttg
     9541 tatattggca gtcttaagag tgaggtctat ttctgtttgt acgaaaaaga ctatgagcaa
     9601 tatatcaagt tagggattcc tttagaccag accgaaacga aaaatcgttt tgaaatccga
     9661 ctgaaaaatg atcgagctta tcatgcaatt caagatttgt taaaaggtcg cagtattgaa
     9721 agtaccacat tttccattat taaccggtac ttgcgatttg cggataaggt ggaaggcaaa
     9781 aggcgaacta actggccctt gaatgaacaa tgggggcgct tcattggacg gaatcagaag
     9841 gaaattcaat taacttctga accgaagcct tataccattg aacgaacgtt gaactggctt
     9901 ggacgacaag tcgcccctac gtggaagatg gccaaggagt tggatcggtt gaatcagaca
     9961 acgtacattc aggatatggt aaataatact cgactatcag accggcacaa aaagattttg
    10021 gagcaacaaa gtatggcaat tgaaaatttg attatatgaa aagaggaatc gtgatggaaa
    10081 ttgtgaaaga tattttattg gtgtttggtg gcagtatgct tggtgttact gtgatgtgct
    10141 tgatgcatgc aagtgcagcg gcggaccgag caatggaaaa gaaaggaaag tgatgaaatg
    10201 aatttcggtc aaaatttgta tcaatggttt ttaaccaatg ctcaatcttt agtcttacta
    10261 gcgattgtgg tcattggttt gtttttagga tttaaacgcg agttttccaa actgattggc
    10321 ttcttggtga ttgctttgat tgcggtaggt ctggtcttta atgcttctgg tgtgaaggat
    10381 gtcttactca atttgtttaa ccgaattgtc ggtgcctgag ggggaatcac aatggaacag
    10441 atacgtgttt atattgcgaa ccttggaaaa tacaatgaag gtgagttggt gggggcatgg
    10501 tttaccccac ccgtcgattt tgatgaagtg aaagaacgga ttggattaaa tgacgaatat
    10561 gaagagtacg caattcatga ttatgaactg ccttttgaga ttgatgagta tacaccaatt
    10621 gaggaaatta atcggttgtg tggtttagcg gaagagctta aaggaacgcc aattggtgag
    10681 gtcgcttcag agattcaaca tgccttcttc aattctttcg aggaaatggt agagcatgtg
    10741 gatgatatca tctattatcc cgattgtaat gacatgagtg atgtagcgta ttacttgatt
    10801 gtagaagctg gtgatttagg cgaagtacca gaacacttga agacgtatat tgattttgat
    10861 gcgtgtggtc gagacttgga gattggcggg aattatttgg ttacgagtcg aggggttttt
    10921 gaactaatgt aaatcatttg ttagaattga ccagaaattt ctatcgtact tttacttttc
    10981 tatttgatat actgaaatag aaaatatttg ttgatagggg tgttactaat ggttggcaat
    11041 aagtggtaca aatgtgatct tcatattcat tcaactgcga gtcagtgctt tcaggataaa
    11101 aaggttactg ctaaggaatg ggtagaagaa tgtttaaaca aaggactcga ttgtgttgca
    11161 ttaactgatc acaatacagg ggaaaatatt gatgaatata agaaagtggc tatcgaaaat
    11221 ggcttagatt tttttcctgg agtggaatta acgtgtggag aaaatggaac tcatttacta
    11281 gtcctatttg ataaaagtgc atgtacaaat gatatctctg atttcttaac caagatgggt
    11341 ataaaaagag aggattgggc cagcgctgca gcttgctcaa tgaaatcagt tttagaagtt
    11401 attgattttg ctgagcacga gggcttgctc gttattcctg cacatataga tgagtttaat
    11461 ggaatttctt cagcaaaatt tggaaatcta ggaaagatat ttgaatcaga aaatatatat
    11521 gcagtacaga cggttcaaaa agaatttttt gaaaatcgct cacaaatgat tccctcatct
    11581 aagcgtgaca ctatctatga tagtgtgaat gccagatatg atggtagagt tggaaaagat
    11641 actttggaat cttggtataa atcagttgtt gaggcagaaa aaaataatat gacatttctt
    11701 agcttttctg ataacccaca ctcgaaagga aattcaaaac atggactttg gggaataggc
    11761 acaagatatt cctatataaa aatgaaggac gaacctgact tgggatcact tcgcgatgct
    11821 ttaatgctag gcgaaactcg agttcattct gatttttcta atttctccat taatgaaaat
    11881 gaagttttat tggaaaaatt aagcttttct gggaccactc ttagcacaaa agaagttgta
    11941 gtcgaattca gcgataattt aacttcaatt attggaggaa gaggaacagg caaatcttgt
    12001 attacaagat tcttggtcta tgtccttgga aaggaagcag aacttgatca attttctgaa
    12061 atacaaagtg attatcagaa ctttgcacaa attgaacata atggctctgg aatatttttg
    12121 aaggatacaa ttgtgaaact gaatattttc tataagggga caaaatatca aataataaga
    12181 acacaggata gacattctat ttatgaattt acacaagaga atggtctggt tgaaaaagaa
    12241 acagaacggt tgagaatgat ttccgataag gtgagtatat actctcaaaa acaaatttat
    12301 gaaatttcaa aaaatcaaac tagtatacta gaattactag atggatataa ctctgatttg
    12361 atttcagagt ataaaaatga gattgaaaca tgtgtaaacg aaataagaaa attaaattgg
    12421 gatattgttt ctgtgaaaaa agaaatacaa gataaggcga aggtagagct tgaaattgaa
    12481 gatttaaaaa aacaagtaga aaagctatct cataagagtt ataaagatgt ttatgatgag
    12541 tattcaaaag agacagatat ttatagggaa ctgaaacgtg atgtggaggc acttaaggaa
    12601 attcccaaaa atctaactga tagtgttgac aaaattgact ttggcaatgg tataaaagtt
    12661 acagacgaaa ttgatgaaca ccgcggagaa ttgattaaga atttagtgac caatcgggct
    12721 aagattcaaa caataattaa tgaaatgtca gatgaaattg atagttatag agcagagctg
    12781 aataaatcag attggaaagt taactataat gaggtttcaa agaggtatca aagaggtatc
    12841 aaaaacttag tgaagagtta tctcaagatg aattaaaaat gttacaaaac cttgattctt
    12901 tatatcaatc tttatcaaaa actgaagagc gattggaaga aattattcaa caagaaataa
    12961 agcttaaaga ttaccaagtt gaggttgact cagcaatgtc aagaatgaat aaatcatatc
    13021 aaaatttcta ttctgagaga agtagttcct cgcgcgaaat tttttctgat attacaggaa
    13081 tagaggctac tattcaacca aatagggatt tcaataatta tgttaaagag ctcagagctt
    13141 gtattaataa ggaggacact tttgacagtg agtttggatc tcttattgat aagctgacaa
    13201 aaaattccat tactaatcaa gatatatata atgacatact tgatataaga gttagtgggg
    13261 aaagtagtat tttttcagat aaaaaattaa tcaattctat aagaaaattg aatgatgcac
    13321 aagttcttga attacaaacc cttaagccaa atgatttagt agttatccga cttgaactaa
    13381 atggaaaaaa agttagttta tcgaatgcta gtgctggtca aaagacatct gcaattcttt
    13441 ctatgatttt ggcgtatgga aattcaccac tcatattgga tcagcctgaa gatgatttgg
    13501 atagtcaatt aattaataac ttaatcgtaa gaagtatcat tacaaaaaag gaaaacagac
    13561 aaattttaat tgtaactcat aatgcaaata tcccagttaa tggtgattca gaatggttga
    13621 ttagcatggg agattcaaaa gaaatatcgg ctgatcagtg cgggtcggta gatgaaccca
    13681 atatcaagcc aagaatatgt actgtgatgg aaggtggcga ggatgctttt acaaatagag
    13741 cgaaacgcta tggttttaaa caaattgtag aataacacta gagggtgaga catattatta
    13801 tgtccgccct ttttaggagg aaaaatgaaa aaaataaaaa gctataccag tatctgggca
    13861 gttgaaaaag tcatttacgc aatcaatgat tttcagttgc cttttcctgt gacttttaac
    13921 caaatggctt ggttcgtttt atctttactg tttgtcatcg tatttgccca tgtgcctcca
    13981 ctatctatga tagaggaggt ctttttaaaa tacttaggca taccggtggc tgtcacttgg
    14041 tttatgtcgc aaaagacgtt tgatggcaag aaaccactgg gatttttacg atcctttatc
    14101 agctatcact tgcgatttaa ggtgactttt gcaggaaaga aagtcaaaga acagaagaaa
    14161 cgatgggatg aacccagtac tcttgtaagg agtgtgaact atgtatccga ttaagtatat
    14221 tgaaaataat ctcgtcttta accaagaagg cgagtgtttt gcctactatg aattagtgcc
    14281 ttacaattac tcctttttgt cacccgaaca gaaatttcaa gtgcatgata actttcgcca
    14341 actaattgcg caaaatcgtg aaggcaagat ccatgcgtta caaattgcca cagaaagtag
    14401 tattcgcgcc acacaagaac gatcaaaaaa agaaattacc ggtagactca aagaagtagc
    14461 gaaacaacga attgatatac agacagatgc attagtatcc atgattggcg atagtcagat
    14521 tgattatcgc ttttttattg gctttaaact aattgcgaca gatgaagaag tcaatctaaa
    14581 gagtctcaag aaatctttct tttctgggct tcaagaattt gtctatggag tgaatcatca
    14641 tttgatgggc gattttgttt ccttatccaa tgaagaaatt cgctgctatt ctaagcttga
    14701 aaaattaatg gaaagcaaat tggctcgaag atttaaagtc aggcgagtca caccgagtga
    14761 cctgacgtat ttgattgaac atatttatgg cgaaaaaggg ataccgtttg aagaatacga
    14821 atttcagcta ccaaagaaaa agctaaaatc agaaacactg gtgaaacgtt atgacttatt
    14881 acgtccaaat cgttgtttaa ttgaagaaaa accaaggtgc ttacggatgg aacatgagaa
    14941 tcatgagtcg tacgtagcgt atttaacaat taatacaatt gtgggggaga tggaatttcc
    15001 ttcctcagaa cttttctatt accagcaaca acaatttaca ttcccaatcg acacaagtat
    15061 gaatgtagag attgtgacga ataaaaaggc tttagctacc gttcgtaata agaaaaaaga
    15121 actgaaagat ttagacaatc atgcttacca atctgacaat gaaacgaatt ccaatgtctt
    15181 agatgctttg gattccgtgg atgaattgga aaccaccttg gatcagtcaa aagaatctat
    15241 gtacaaactg agttatgtgg ttcgagtgag tgccgaatca gtggatgaac taaagcgacg
    15301 ctgtgatgaa gtgctcgatt tttatgatga taccaatgta aaactagtcc ggccctttgg
    15361 cgatatgatg gggctacatg aagaattctt acccttaagt aaacgatata tgaacgacta
    15421 tattcagtat gttacgtctg attttttggc ggggcttggt tttggggcta ctcagatgct
    15481 aggagaatta gaagggattt actttggcta caatgtggat acaggtcgta atgtttacct
    15541 gaaaccggca ttggcttcac aaggagtcaa gggttcagta accaatgcgc tggccgccgc
    15601 tttcctgggt tctcttggtg gaggtaaatc ctttagtaac aatctcttag tctactatgc
    15661 tgttttgttc ggtgg
//
LOCUS       DBBGRF010000062        15314 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000062 DBBGRF010000000
VERSION     DBBGRF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.062"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            278..787
                     /locus_tag="ACIZD4_002385"
     CDS             278..787
                     /locus_tag="ACIZD4_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC5991269.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="ACIZD4_002386"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="ACIZD4_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC5991270.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLTPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="ACIZD4_002387"
     CDS             2322..3302
                     /locus_tag="ACIZD4_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5991271.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="ACIZD4_002388"
     CDS             3424..4842
                     /locus_tag="ACIZD4_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HGC5991272.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="ACIZD4_002389"
     CDS             4913..6382
                     /locus_tag="ACIZD4_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC5991273.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="ACIZD4_002390"
     CDS             6392..6859
                     /locus_tag="ACIZD4_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGC5991274.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /gene="scrK"
                     /locus_tag="ACIZD4_002391"
     CDS             6895..7767
                     /gene="scrK"
                     /locus_tag="ACIZD4_002391"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGC5991275.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7849..10383
                     /locus_tag="ACIZD4_002392"
     CDS             7849..10383
                     /locus_tag="ACIZD4_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HGC5991276.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10539..11312
                     /locus_tag="ACIZD4_002393"
     CDS             10539..11312
                     /locus_tag="ACIZD4_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGC5991277.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11305..12096
                     /locus_tag="ACIZD4_002394"
     CDS             11305..12096
                     /locus_tag="ACIZD4_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGC5991278.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12106..12597
                     /locus_tag="ACIZD4_002395"
     CDS             12106..12597
                     /locus_tag="ACIZD4_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HGC5991279.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12615..13025
                     /locus_tag="ACIZD4_002396"
     CDS             12615..13025
                     /locus_tag="ACIZD4_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGC5991280.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13029..14429
                     /locus_tag="ACIZD4_002397"
     CDS             13029..14429
                     /locus_tag="ACIZD4_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HGC5991281.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14452..14826
                     /locus_tag="ACIZD4_002398"
     CDS             14452..14826
                     /locus_tag="ACIZD4_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC5991282.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5315 a         2156 c         3060 g         4783 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga cccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttt caattagtaa ttgaagggac gcctaaaagt gaaaaaaaaa
     7861 atgaaagatg aagtattaga gtatatcaaa aataatttaa agtattacga tttttctgct
     7921 caagatattg caatgaaatt ttgtattaaa agaaatgtcg cttcccacta tttgaatcag
     7981 ttattttcag atggaaaatt actaaagaat gattctgtta gaccagtaat gttcaagtat
     8041 aatcaacaaa agccaaaaga ctgcttttct aagtttattg gagcagacat atctttgaaa
     8101 tccactatag ataaatgcaa agctactgta atgtatcccc ctaatggcct cccattaata
     8161 ataaaaggaa acagtggcgt tggaaaaagt tttttagcaa gtttgatcta tcagtatgct
     8221 cttgatagaa aagtaattca taatgacgca aaatttgttg ttgtgaattg tgcagattat
     8281 gcaaataatc cagagctatt gtcagcagtt ttatttggat ataaaaaagg agcctttact
     8341 ggggctgaaa aagatactgc agggatgcta tcttctgcta atggaggata ccttttttta
     8401 gatgaggttc acaatctaag tgcagaaaac caagagaaat tgtttcttct tatggattct
     8461 caaaagtatc gtaaacttgg tgaaagtgtg caatgggagt atgcaaatgt tcgccttatc
     8521 ttagccacaa cagaagataa aaatacctct ttgttagcaa cttttagaag acgcatccca
     8581 gctgaaatca ctctgccaga ttacaataat agaagtacat ctgaaaaaat tcaattatta
     8641 tttgaatttc ttaaagatga agcaattaca attgattcaa aaatattttg ttcgattgaa
     8701 ctttttactg atcttttatc gaaaacattt gaaggaaatg ttggagaatt gaggaatgaa
     8761 atcaagcttc tttgtgcaga aggttattta ggaaataaga gaaagtcttc aatttattta
     8821 ggggacaaac tagacagcgg tttttggata gatccagaaa ttagtataga tttaaaaaaa
     8881 atgtttctta aatcactttc tgaaattgat ttgattgaac tttttcaaaa tcacatttca
     8941 attgaagaaa gcatgagtca attaagagat agaatactta aagagtgtgc aggttcttct
     9001 gagtataatt atttagaaag tgacgaattt atagcattaa gaaactatgt tgttaataaa
     9061 atatcaccaa ttattgattc gacaggtcta tgtttattag atgaattctt ggcggatatc
     9121 agtctattta taatgtttat tgatgtaatt gaagaaacat caagaaattt tttgctgtct
     9181 aagttcagaa aatttcgtat gaaaaatgat aaacaaaaat tattggcaaa tgagatttgg
     9241 agtagtttag aagtcgaaga aagtaaacaa gaacttttgt tgaaatggat actttttctt
     9301 gtaaagaagt tctatgtgaa aataccagaa acccattgtc tgatagttat gcacggtaaa
     9361 ataacagctt ctgcgatcgc aagggaaaca aataagttgc tgaatacata tgtttatgag
     9421 gctttcgata tgccaattga aggtgagact agtgacttaa ttaacctaat caacaatttt
     9481 tgtaaaagta tagatacgac gaatggactc attctgctag ttgatatggg atcattggaa
     9541 caaatgtatg aaaaaattga atccaatgta ataggtgatt tggtaatttt aaacaatgtt
     9601 tctacagctt tagcgattga atgtgggatt caagtttgcc aaaaaaagcc aattagtcat
     9661 ttttaccaga tggattttga ttcgtttcaa gttaaagttc agtattataa aggattatca
     9721 caaaagaaaa atgtaatagt atcttgtctc tctggtgagg ggatttctga aaaagttaag
     9781 gatattttaa aacggtatct cgataatcaa gtggagattt tgatttttga ttttaacgca
     9841 ttaaagaaaa tagcaaagga aaaagatact atgattttta agaatacaat ttgtgttctt
     9901 tcaaccactg aattttacat tcaaggaatc gattgtttaa atttagaaaa tctaattaat
     9961 gggaatcaaa ccttagaaaa attaaataag tatatggact cggatagctg tgagttctgc
    10021 ttaaatgaat tagttaaact ctttactatt gaaggcgcta gtactaagct tcgcttttta
    10081 gattccaaaa aagtattcaa tgagatagaa aaagtactat atttgtatga aaaatattac
    10141 gatgtcaaaa tcccaagttt tctgagaatt aatctatttc tacatctttc tggaatgatt
    10201 gaacgaatta tgattggtga tggaataaca aatgaacatt tgaaagaggg agcgcaacta
    10261 tttgatactt ttttaaatgt atcaaaagat tttttttcag aaatcaaaga tatttactgt
    10321 attgaaatac ccaaaggaga gtatgagtta atctatacaa tttttgagca gactattttc
    10381 taaatagcat actagcgtct aaaaaaatga aagggtgtcc aaagtatatt tagacgctca
    10441 tttaattaat atttactgta ttttcccgct ttattggata atgttagttg gcacagtaat
    10501 tgcttatata aaagtataag aagaaaggag agaacaaaat ggcgttttgg caaacatttt
    10561 tagttgtgtt gtatggattt ttcattaact gggataagga agggcccaaa atcggaacct
    10621 cccaacctgt cgttgcaggt ttcttgaccg gacttattat gggagatatt caaactggac
    10681 tttatatcgg tgggactttg caattaatga cactaggtat tactagtttt ggtggtgcat
    10741 cagtaccgga ttatcaaaca gcagcattga tcggtactta tttagcaatc tcaactaacc
    10801 aggatgcttc tataggaata actttagcaa taccggtagc aatgttaatt gtacaactag
    10861 atgttctaaa gtggtcaaca aacatttttt ttcaacaaaa ggcagaaaaa ttcgcacaaa
    10921 aagaagatta tcaaaaatta gagtggatgc aatatttggc atcaattaat acaagctttg
    10981 tatctggaat tcctgttttg ttaactgtga tattaggccc aacgttagtg ggaagtgcaa
    11041 tcaattatat tcctgaatgg gttaccggtg gtttaaaggt agcaggggga ctattacctg
    11101 ctgttgggat aggaatgcta cttaaatatt tacctacaaa agattacttt gcctatttgt
    11161 tagttggttt cgttttggca gtttatttcc aaataccaat tttagggatt tcgttacttg
    11221 gcgctgcaat cgcactaatc gtatataaaa atagatcaaa taatactcaa gtagcaccag
    11281 ctgcaacagg aggttttgac gaagatgaat aagaaactga caaaaatcga caaacaagta
    11341 attttccggt ggattctcaa tggtgcaact tcattaaatt atgaaaaaat ggaagggttg
    11401 ggttatgcgt attctatgct tccttttatc aaggacacat ataaagatga tcctgaagga
    11461 atgaaacaat ccgttttagc tcacctacaa ttttttaaca ctacgccgta tacagcgcct
    11521 tacattattg gtatgaatgt tggaattgaa aaagaagaaa aaaataagtc tttggaagca
    11581 gtaagtgctc tgaaaacagg tctaatgggt cctttagcgg gaattggaga tagtgtattt
    11641 gtagttattc catggactat ttttggagca attgcagcta atatggcatt ggaaggtagt
    11701 tttgttggaa ttattttgtg gatactggca tcaattttat taaggattac tgcttatcct
    11761 ttataccttg ctgggaaaga atcgggtgcg agcctactaa ctcaaattga aacaaaatta
    11821 aagtctatta ctgatgcagt atcaatttta gggttaatgg tggtcggtgc actcattgcc
    11881 acagttgtaa aagtgaatgt tggctttgaa tttaaacaag gcgacttaac aatgaccgga
    11941 aatgaaatct ttgatcaagt tatgcctggt ttattacctg catgtgtagt agcaattgtg
    12001 tattatttgt taggacgaaa ggttaaacca gtttatgtaa ttctattaat cttagtagtt
    12061 tctattgcgt taagagcgtt aaatattttg aagtaggtgt tgaatatgga tgaaaaaatg
    12121 aaaggtatta tacatgttcg tattgatgat cgaatgattc atggacaagt agcaacacaa
    12181 tggacaaatc aattgagtgc taacagaatt atggttatta ataatgaagt agccaatgat
    12241 gacgtaaaaa aagctgtagt tcgcctcgct gcaccaccta atgttagaac ttcaataatt
    12301 acaagggaag tagcagttaa aaatattctt tctggtaaat atgaaggaca aaaagttctt
    12361 attgttgcag tttctccaat cgatgttaaa tttttgattg ataacggttt accaataaca
    12421 agtgtaaacg taggaaattt atcaagaagg aatggaacag aacgcatccg tccgacgata
    12481 aatattactg aagaagagag agaggctttt aaagaactaa ttagtgatgg agttgaagtg
    12541 acagtgatac aaactcctag agattcaaaa gaatttttaa aggattttat ttattaagaa
    12601 cagaggatga gtggatggag tttataatta catctcatgg aaatattgcc attggatttg
    12661 tagatacatt aaaaatgttt tttggcgata atttaaattg tcatgtggta acacttggag
    12721 atgcaggcat tgaagaattc cgtgaaaaca ttgaaaaaat agtttctcaa gtaaaaaatc
    12781 aagaagttat ggtatttgct gacttgattg gtggaacacc tttcaacgaa tttgctaaaa
    12841 gaagtgaagt atttcaaaat gggtttcaac ttcttggtgg catgaattta ggaattttga
    12901 ttgaggctgt caatttgaga ttacaaggaa aaaaaagcga tgatatcatc gaaaatctaa
    12961 gaaatatgaa tacaattgcg tgtcttgcag atatgcaaag acatactaac gaagaggatg
    13021 agtgataaat gcaaaaaatt ttttacaagc ctaaagattt ttggtttggg gattgcatgc
    13081 ctttttataa agatggaact ttttatctat ttcatcaacg agatacgaga aatcctaaac
    13141 ctttaactga tccttttggg tggtcactag ttacaaccac tgattttgtg aaatttgaag
    13201 aatacgggga agtaattcat cgtggtggca acgatgacat tgatcaatac atttacgctg
    13261 gaagtattgt ccaaggaatc aatgagtatt tagctttgta tactggacat aatcgcaaag
    13321 ctaagttgga tggaaaaact tcagaagtgt taatgattgc aagttctaaa gatttaattc
    13381 attggaaaaa ggatggcgaa gcagcaaaac ttgttcctca agaaggatat gataagaatg
    13441 attggcgcga tccttttgca atttttgatc aagatcatgg aaaatacgtt ttgatactag
    13501 gagctagaaa accagcaagt aagaaaaagc cgacggggag attggtctat tttgaatccg
    13561 aagatttaaa agattggaat ttcaaaggag actactgggc taataatgaa tttaacatga
    13621 ttgaaatgcc tgatatattt gaaattgatg gaacgtggta tttacttttt tcagagtatt
    13681 gtgaagataa aaagactaaa tatcgagtcg gagcaggatt attttcagat tggaaatcac
    13741 cagtagacga agctttcgac ggaaaagcct attatgcagc aagaacagtc ggaactaatg
    13801 aaactggccg ttttctaact ggctgggtgg caacaaaaga aggggagaac gatcaaaata
    13861 actgggattg gggcggtgca cttgttccac atcaaattat tcaaaagaca gacaaaactc
    13921 ttggtgttaa actgcctgaa aaaataattg agaattttaa agaaatcact ccattttcaa
    13981 gttttaagtt agagaaagaa tttggaaaaa aagaaagagt aattgttcct aaaatcgaag
    14041 attattttct atttgaaaca actttgacta ttacatcgtt aacaaaggag tttgctttaa
    14101 aattatttgt agatagtgat actcaagaag gatacgaatt tcgtatttca ttgattaata
    14161 atcagcttac tttcggaaaa actccgaact atccttggcc tcaaatgttt gataaggggc
    14221 tgcaacgacc actatttttg gaaataggca aagaatatga actaaagtta attgttgatg
    14281 atacgatagc tgttttatat attgataatg ttgctttaag tactagaatg tatgataaag
    14341 tcggaacagc attaagtatg actgttacgg agggagcaat caaggtagat aaactagact
    14401 attcaataaa ttatgaatgt ggattttaaa acaattgaag ggatgatgta agtgaaatta
    14461 aatggtttac aacatattgg aattccaaca aaagattttg gagcttcaaa aatcttttat
    14521 gaatccttag ggtttagtct gattaatgaa gaaatgaatg tgggaagtaa agtcggcttt
    14581 ttcgagttga atggaacgat aatagaaata tgggaagata aaactactga gtgtagagga
    14641 gccattgatc atctagcatt agatacggat gacatagatg aggtattcaa ttcaattcaa
    14701 gatttaggat atgaattatt agataaaaat attatggaat taccgttctg ggaaaatgga
    14761 atccgttact ttaatttcta cggaccaaat catgagatta tagagataag ccaaatgaag
    14821 aaataaatag ataacgaagt gctctaagtt ggtatgaacg aaaagtactt cattttttgg
    14881 tatcagcatt tcaatagttt aatgagaatt tactatttca aattaattca aagtgacagt
    14941 attttttact tatttggttt caaattttgt aatccttcct atttattgga atacactcca
    15001 cattttgtat acaagtcata tcatgtttta gcaaagctct taccaagcaa agttataatg
    15061 atgttttcca aagtttgatc tttcgatgga ggctaacaca tattttttgc aggacagcca
    15121 aaattagatg tatagaatag agtctgtgag gcgtatagac agtttattgt ctgtatgcct
    15181 ttttttattt tgaaaaattt ttagtatttt tcgaaaaatg ctcactccta gagtaagcgc
    15241 cccatagaac agtaccttac taacaaatgc acctcaagat atacttgagc tatcaagaag
    15301 tctggaggtt ttct
//
LOCUS       DBBGRF010000063        15258 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000063 DBBGRF010000000
VERSION     DBBGRF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.063"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            2..1021
                     /locus_tag="ACIZD4_002399"
     CDS             2..1021
                     /locus_tag="ACIZD4_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HGC5991283.1"
                     /translation="MSIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDHQLIT
                     GKLMNSDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGWLFFF
                     TSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNKSILFVVIGMI
                     ISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRPYRSV
                     FLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSMTNIL
                     LFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLFFLTV
                     RRLKR"
     gene            1018..1785
                     /locus_tag="ACIZD4_002400"
     CDS             1018..1785
                     /locus_tag="ACIZD4_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HGC5991284.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALIVLPLTCVTTAYLFTKKKEQLKME"
     gene            1885..3453
                     /gene="liaX"
                     /locus_tag="ACIZD4_002401"
     CDS             1885..3453
                     /gene="liaX"
                     /locus_tag="ACIZD4_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HGC5991285.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDKASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQALEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            3750..4070
                     /locus_tag="ACIZD4_002402"
     CDS             3750..4070
                     /locus_tag="ACIZD4_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGC5991286.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            4070..4420
                     /locus_tag="ACIZD4_002403"
     CDS             4070..4420
                     /locus_tag="ACIZD4_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HGC5991287.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            4587..5525
                     /gene="hprK"
                     /locus_tag="ACIZD4_002404"
     CDS             4587..5525
                     /gene="hprK"
                     /locus_tag="ACIZD4_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGC5991288.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            5540..6370
                     /gene="lgt"
                     /locus_tag="ACIZD4_002405"
     CDS             5540..6370
                     /gene="lgt"
                     /locus_tag="ACIZD4_002405"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGC5991289.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            6414..7439
                     /locus_tag="ACIZD4_002406"
     CDS             6414..7439
                     /locus_tag="ACIZD4_002406"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGC5991290.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            7454..8392
                     /gene="galU"
                     /locus_tag="ACIZD4_002407"
     CDS             7454..8392
                     /gene="galU"
                     /locus_tag="ACIZD4_002407"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGC5991291.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            8517..8957
                     /locus_tag="ACIZD4_002408"
     CDS             8517..8957
                     /locus_tag="ACIZD4_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HGC5991292.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            8960..9562
                     /locus_tag="ACIZD4_002409"
     CDS             8960..9562
                     /locus_tag="ACIZD4_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGC5991293.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQGLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(9625..10728)
                     /locus_tag="ACIZD4_002410"
     CDS             complement(9625..10728)
                     /locus_tag="ACIZD4_002410"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HGC5991294.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            10938..11939
                     /gene="ccpA"
                     /locus_tag="ACIZD4_002411"
     CDS             10938..11939
                     /gene="ccpA"
                     /locus_tag="ACIZD4_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGC5991295.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            12294..12689
                     /locus_tag="ACIZD4_002412"
     CDS             12294..12689
                     /locus_tag="ACIZD4_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991296.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREMQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTGSYRIVILMTNKQDQSIYFSYSFWKERNEIGSY
                     GIVDEKKQKEGNTLNKVKVTYSNGNEESI"
     gene            12689..12940
                     /locus_tag="ACIZD4_002413"
     CDS             12689..12940
                     /locus_tag="ACIZD4_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991297.1"
                     /translation="MITDKQYSELSDAVYWLDPKHRDYVPEMQENLSFKINGTMYKIL
                     KIKNSFDGMQAMAVAPIVHSKLEKNFKNKKIPANFRVLK"
     gene            12983..13378
                     /locus_tag="ACIZD4_002414"
     CDS             12983..13378
                     /locus_tag="ACIZD4_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991298.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGSYGALVTMTNNEGKSVYFDYSFWKERNELGGF
                     GIENRAVQKTGVTIKRVKVIFSNGQEELV"
     gene            13375..14631
                     /locus_tag="ACIZD4_002415"
     CDS             13375..14631
                     /locus_tag="ACIZD4_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HGC5991299.1"
                     /translation="MTINDKHYNDISEKVYWLDPKYPRYNEGYKKNSVKEFAGMEFQI
                     LQIKDSLDGMQAMSVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            14643..14966
                     /locus_tag="ACIZD4_002416"
     CDS             14643..14966
                     /locus_tag="ACIZD4_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991300.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            14959..15225
                     /locus_tag="ACIZD4_002417"
     CDS             14959..15225
                     /locus_tag="ACIZD4_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991301.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNYQ
                     MTAEEAAQEFSNRHVHLKGSVKGQFAEKLTELFQRQEKKLKQFR"
BASE COUNT         5242 a         2580 c         3227 g         4209 t
ORIGIN      
        1 aattagcatc atcactatat tttttatttg tgtgcttact tcatgggtta ttcagcatca
       61 agccgcttta tatgaagtac ctgtcatcga gatagaaaaa gtacgaataa aagaggatca
      121 tcaattgatt acaggaaaac tgatgaactc ggatcaaaaa ggagaatcga tttatttatc
      181 ggttccttat caaaaaaatc aaatagaaac agcaaatata aaagcgagac aaatgtatct
      241 agtccaaatg catggagatg aatggcagct agtagcaaaa aaaaatgatg gctggctttt
      301 cttcttcaca agtatcttca ttggcgccat gttgcttatt ggcggaaaac agggtctatt
      361 tgctttagga agtctcatca tcaatatcgt tttactttta cttttgttgc tcatctttac
      421 taaaacagaa gggatttctc tattaaataa atctatcctg ttcgtcgtta tagggatgat
      481 tattagcata ttggctttag atggatggaa tagaagcagt ataatcaaaa tttcagctgc
      541 agttacgagt gtttttttag cattttttat ttgtcttttg acaatgaatc attggaaaga
      601 ccaaggactg cgctatgagg aactgaatta tctgacacga ccgtatcgtt ctgtttttct
      661 ttctagcgta ctgattggaa cagctggagg aacactcgat accgttatca cagtcattgc
      721 gacattagaa gaattgacta agcgacaacc agaaataaca gcgaaacagt tatggctttc
      781 aggaaggcaa gtgggtcgag atgtgattgg ctcgatgacc aatatccttt tgttcgtcta
      841 tatcagtggg tcagttccat cgcttctttt atatttagga aatcaatggt ctttcaaaga
      901 aacgatagaa cagcatttat cattggaatt tttacgcgtc attgctggca gcttaggaat
      961 agtattatcg atccccatct cggtcctctt ttttctgact gtaaggaggc tgaaacgatg
     1021 aatgtactta ttatacttgt tgggatttta gcaatcagcg tgctacttat tggcggtacg
     1081 caaggtatgt atattctttt aggcttattc atcaatttag ggatcttttt cctgttgtta
     1141 ttcggttatc atcagaagtg gccgatactg gcattgtcgg tcataggatt tttattgatt
     1201 gctgtggtta tcttattttt tatcaacggt tataatctaa aaatgcgtgc agcttttgtg
     1261 agtatactga tctttttatt ttgtttccta ctattgcttc ctatcactga ttttttagcg
     1321 atccaaggtt ttacatcggt agaactagaa gaattatctg gcttagataa gactttagcg
     1381 attgatttta gattacttac gagatcgttg cttctgatta gtcttagtgg tgctgtttta
     1441 gatgcgagtg tagcaatttc tagtgggaca ttcgaagtat atcaggcaaa tccgcaatta
     1501 tctttttacc aattgcgcca ttctagtttc gctattgcta aaaaaatatt ggcgtcaaca
     1561 gtaatgacac ttctttttgc attcatggga agttctttag cgttgatcct ctggtttatt
     1621 gatttagaca ttccttttca gcaagtgatc aatgaaaaat catttgttct agaatatacg
     1681 atggctattc ttaccacatt gtccgcacta attgttcttc ctttaacctg cgtgactaca
     1741 gcatatctct ttacaaaaaa gaaagaacaa ctcaagatgg agtaaaagtt acaacttaag
     1801 tcctatgaca tttttactga atcagtgcat aatatggatg taaggaaaag cttgcaaaca
     1861 attttgctta aggaggcaat ttccatgaaa gaaagagaac gtattttaga tttagtgaaa
     1921 aaaggaatcc tttcgactga agaaggctta gatttattag aaagcatggc aactgaaaaa
     1981 gacgaaaagc aaatcaaaaa agaagcagac aaggtaactg ctagtcataa agaaaaagat
     2041 aaggcaagtc aattgatcga taaacttgaa aacggcgaag aagaaatttc tgagccagtt
     2101 gatccaaagg aaagagaaag acaagatcaa gaaaacttag aaaagatctt agatgaacta
     2161 gcaactgaag cgaataaaac ttcggcgcgt ctagatgaag taaatgctca attcgctgac
     2221 aataaggcag cacgcaatga gaaacaggaa gcattgatgc agctgaatac aaaagaagaa
     2281 ttaggcgagt tgacagaaga agaattagca cagcgtcagg cgttagaggc agaaatcaaa
     2341 gagttagaag ctagtggcga tacactgtta gaagaacaat tgaaattaga agcagaatta
     2401 aaagatatcc gtaagaatca atggtctgag aaaaaagaaa cgtttactga taagtttgaa
     2461 ttgccagatg attggaaaga tcaagcaaca gatacactga atcaagtagg cgaaaaaatg
     2521 tcagaagctg gatcacagtt aggcaaattc ttgaagaaaa cattccaaac tgtttcagaa
     2581 acagtgaatg acaacatgga atggaaagat gtcagcttac gtgtccctgg gattgcgaca
     2641 acgaaatttg agcatgaatt ttactatgaa gctcctgcag caagtatcct tgatatcaag
     2701 gcagcaaacg gaaacgtgac gttaaaaacg tgggacagca acgatgtgaa agttgaagct
     2761 aagatcaaac tttacggaaa aatgggtgct gaaccatttg aagcattctc tgaacggagc
     2821 cagattgagg ttaatgaaga tcatatctcc ttccaaattc caaataaacg tgtgcgtgca
     2881 gaccttgttt tctacttacc taaacgagta tacgaccacg cagctattaa acttctaaat
     2941 ggcaacatca tgattgaaac attggaagct aaagatattt atacaaaatc tacgaatggt
     3001 aacatcatcg tggaccaatt aactgcaacg atgctggaag tagaaggtgt aaacggcaat
     3061 atcgatattc gaaacgggaa catcttagat tctattatcg aaacagtaaa tggtacagtg
     3121 acatttggtg cgacagcaga aaatctttct gtgtctttag taaatggtga tgtacgtctt
     3181 acgattaaag aagataattt gaaaaaagta gaagcaagtt cagtgaacgg aaatgtcaaa
     3241 gtcgctttac cagatggcat cggtttggaa ggacatgcta aaacaagtct tggaagtatc
     3301 aatagccgtc tgtccaatta cgaagtagtt cgtgagaaaa aagaacggac aaaccaaatg
     3361 ttgcaattcc gtcgtgtttc agatgatgag atcgcgcaag tgcaactttc aacgacaaca
     3421 ggaagtatct atttaaaaga tacagataaa taaagaggtt gtgaaagaga tgttcagcct
     3481 tgagcaataa gaagcgattt tgtaaaatag cttcccctat tttacaaaat tgtgccttat
     3541 tgccgatagt ctatctcttg aacaccgttt accaagagat tatgaacctg ccaattatcg
     3601 ccgagtcaca aggaataatt tcagaaaaag ctcgtcacgt tttatgaata tggtaatttg
     3661 tgaccgagaa ttttgcagaa agacaccgat taagaagaag gttgtcacaa cgattttctt
     3721 catttaaaat agtagaacag aggtgagaca tgatgaaaaa aaagttgaca aaatctaata
     3781 aaaatgttgt tttgacaggg actttagcag gaataggaga atacatcggg attgatccga
     3841 ctgttatccg tgtgctttat gtattcctga gcttagttgc ttttggaagt ccaattattt
     3901 tatacatttt attagctttg attatcccat ctgcgcgttc tgcacgaaca aactatggac
     3961 ataacaatgc atattatgaa aaaaacaatt atcgtgaaca aactcgtgaa caaacaaaaa
     4021 aacgcaaaga agcggaaaaa atcgatgatg acgaatggag tgacttttaa tgtcgtactt
     4081 tcaacgtatt ttagttaata cgttaacatt catatcattg gctgttcttt ttcctgcgat
     4141 ggtccatgtg agcagtattt ggacggccgt tcttgccagc ttcgtattgt ctgtgttgaa
     4201 tatgtttgtc aaaccgattt tgacgatact gtccctgccc tttacattag tcacattggg
     4261 attgtttacg tttgttatca atgcagcgat tcttaaaatg acctcctttt ttgtgggagc
     4321 agaacatttt agtttttctt cattcggtgc agcgttgtta gtagctatct tgatgtcgct
     4381 tgtcaatgta attgtcagcg aacataacag tagaaaataa aagaaagctg tgccgaacta
     4441 tcggcgcagt ttttttattt agaatcagga atgcgttttc tattacattg gtaattaaat
     4501 aaaaacgttt tttttaattg gtagtacttt tggctagaca atgataaaat gatagagaac
     4561 actctaatag aaatgaggta gcatgaatgt cagaagttgt aaaagttagc caattagtga
     4621 aaaaattatc tttggaaatc gtgacaggcg acgagaaaag cttagaccgt gtcatcgtaa
     4681 ctggggacat ctcacgccca ggactagagt tgactggtta ttttaattat tattcccata
     4741 atcgtttaca gctatttggc agtaaagaaa tcagttttgc ggaacggatg atcccagaag
     4801 agcgtttgat catcatgaga agattatgta gtgaagatat gcccgcattt attatttcaa
     4861 gaggattacc agctccagaa gaaatgatcc aggcagcaaa tgaaaatggg atagctgtac
     4921 tgcgttctcc catctcaact tctcgtttat taggagaatt atccagttat ttagatggtc
     4981 gccttgcccc tcgaacaagt gtccacggtg ttttagtgga tgtttacgga ttaggtgtac
     5041 tgattcaagg tgacagtggg ataggaaaaa gtgaaacagc gttggagttg atcaaacgcg
     5101 gccatcgatt gatcgcagac gatcgagtag atgtttatca gcaagatgaa ttaacggtga
     5161 tcggagaacc gcctaaaatc ctggaacatc tgattgaaat ccgaggaatc gggatcattg
     5221 atgtaatgaa tctttttggt gcgagtgcgg tacgtggctc tatgcaagtc cagttggctg
     5281 tttatctgga agcatgggca aaagataaga aatacgaccg tctgggctct gaagacacga
     5341 ccgttgaaat cgcggaagtg ggcattccac aaataaaaat ccctgtcaaa acaggacgaa
     5401 acgttgcaat catcattgaa gtagccgcga tgaatttccg tgcacgtaca atgggctttg
     5461 acgcaacgaa aacatttgaa gaaagattaa gtcgcttgat tgaagaaaac tcaggcaacg
     5521 actagcaagg agtgacaata tgttagcaca aatcaatcga gttgcttttg agcttgtagg
     5581 gattcctatc tactggtatg cattgatcat cgtatcaggt atcattatcg ctatgtggct
     5641 tagcagcaga gaggctgttc gggtaggatt aaaagcagat gatgtgacag attttatgtt
     5701 gtggggattg cctatctcca ttattggcgc tcgcttatat tatgttttat ttgatcttcc
     5761 ccagtatata gctgatccaa tccaaatatt caatatccgt tcaggaggct tagctattta
     5821 tggcggactg attgcaggcg cgatcacgct gtattttttt actaaatatc attttatttc
     5881 tttgtggact tttttagata tcgctgcacc aagtgtatta ttagcacagg caatcggtcg
     5941 ttggggaaat ttcatgaacc acgaagcata tggaccagac acgacgcgaa gcttcttaga
     6001 aagtctgcat ttaccgcaat tcatcattga taatatgtat atcgaaggga tctatcgtca
     6061 accaacattt ctttatgaat cactttggag tttgattgga tttattttgc ttttgttttt
     6121 acgaaagaaa ccacaccttt tgaaaaaagg cgaagtcctt ttatgttatc taatgtggta
     6181 tagtttcggg cgtttcttta ttgaaggatt acgtacagac agtctttact ttttaggtgt
     6241 gatccgtatt tctcaattat tatctgctgt gttatttgtc ggtacattga ttctatttat
     6301 ttggcgcaga aaaaaaggaa atttaccgga ttatgaccgc tcattaggaa aaaatcaaca
     6361 aattatctga tttttagagc gttaaaaatg aaaaaaattt caggagtggt aaaatgaatt
     6421 atagagtagc ggttttagga ccaggctctt ggggtactgc tttggcacaa gtcctcgccg
     6481 aaaacggaca tgacgttcgg atttggggac atcgtgcttc acaagtagaa gaaatcaaca
     6541 cccaacacac gaatcaacgt tatttaccag atcattatct acccgattcc atccaagcat
     6601 tcaccaatat ggaagatgca gtaaaagacg cagatgcggt gctattcgtc attccaacga
     6661 aagcaatacg ttctgttgca aaagaactag tgcctaaatt gaatacaaag ccagtgatca
     6721 tccatgcaag taaaggatta gaacagggaa cacataaaag gatctctgac atcttgttag
     6781 aggaaatccc agcagaaaaa agaaaagctg ttgttgttct ttctggacca agccatgcag
     6841 aagaagtagc aaaacatgac atcactacga tcacagctgc aagtacagat gcaaaagcag
     6901 caaaatatgt acaagagctg ttcatgaata attattttcg gatctatacc aatcctgatg
     6961 tgatcggtgt agagatgggg gcagctttga aaaatattat tgctattggt gctggcgcta
     7021 ttcacggctt agggtttggc gataatgcaa aggcagcaat catgacgcgc ggattagctg
     7081 agatcagccg tttaggtgta gcaatgggtg ccaacccgct gacctttatc ggattaagcg
     7141 gaataggcga tctagtcgtt acttgcacaa gtgttcattc taggaactgg cgcgcaggca
     7201 acttgttagg acaagggcag cccctagaag aggtgctagc caatatggga atggtcgttg
     7261 aaggtgtgaa tactacccaa gcagcgatgg aactagccca aatgatggaa atcgaaatgc
     7321 ccatcactca aacaatctat gaagtgctgt atgaacaaaa agaaatcaaa acagccgcaa
     7381 aagaaatcat gttacgtgat ggaaaaaaag aaaatgaatt ctcattaaca attttttgaa
     7441 ggagcgaatg tatatgaaag ttaaaaaagc agttattcca gcagcaggat taggaacaag
     7501 atttttacca gcaacaaaag ctatggcaaa ggaaatgttg ccaattgttg ataaaccaac
     7561 aatccagttc atcgttgaag aagcgttgaa atcaggtatc gaagacatct tgatcgttac
     7621 aggaaaagct aaacgaccaa tcgaagatca ctttgattca aatattgaat tagaaacaaa
     7681 cctaagtgaa aaaggaaaga ccgaattatt gaaattagta gaagaaacga cagatgtcaa
     7741 cttgcatttc atccgtcaat ctcatccaaa gggtttagga catgccgttc ttcaagcaag
     7801 agcctttatt ggaaatgaac catttgtcgt tatgctaggc gatgatataa tggaagacga
     7861 agtaccattg acacagcaat tgatcgatga ctatgagcgt acacacgctt ctacgattgc
     7921 cgttatgcaa gttcctcacg atgaaacttc aaaatacgga atcatcaacc caggggaagt
     7981 actggaagat gggttataca atgtcaaaaa ctttgttgaa aaaccagatc caagcaaagc
     8041 accaagtgat ttagctatta ttgggcgtta cttattgact ccagaaatct ttgatgtatt
     8101 atcagaacaa caaccaggtg ctggaaatga gatccaacta actgacgcaa tcgatacgtt
     8161 gaataaaaca caacgcgtat ttgcccgtaa attcacaggt aaacgttatg acgttggtga
     8221 caaatttggt tttatgaaaa caagtattga atatggtctg acacatccag aagtaggggc
     8281 acctttgcgt gaatacatca tgtctttagg taaaacatta gaagcagaag gaagcaagat
     8341 caatcataat ccaaaaggaa taacagaaat caaagaagaa aagaaaaaat aatctttttt
     8401 tctaacgagc ttcagctgct aattgaataa aaagtagttg aagctcgttt ttatttgttt
     8461 aaaaaacacg aaaatgctat ccttatagaa aagagagaca agaagggagt ttgatcatgt
     8521 caggaggaga aattgcagga ttgatcgcag caatcgcctt tgcgatactt gtcgttttca
     8581 tcgttcgcgt attgttgcaa gtttccaaaa ctttagaaaa agtagaccag actgtcgcag
     8641 aagcaaatac gacaattgag atcgtcacac aagacgtaga tcttttatct agacaagtag
     8701 aaggcttgct agtcaaaagt aatgagctgc tcttggatat caatggaaaa gtcgcaacga
     8761 tcgatccatt gttcacagca gttgctgatt taagtgaaag tgtatcggaa cttaatcatt
     8821 ctagtaaaaa catcgtgacg aaagtcggcg gaatcggaaa aacgacagct aaagcgactg
     8881 ttgccggaaa agtcggtgga acagcgatga aattttttaa aaacaaaaaa catactgaaa
     8941 cgacaggagg aaaataagaa tggctaaaaa aggtggattt ttattaggtg cagtagttgg
     9001 aggtacagcc gcagcaatcg ccgcattatt gttagcaccc aaatctggta aagaacttcg
     9061 ggatgaattg gctgctcaag cagatgattt gatggacatg gcttcagatt acacagatat
     9121 ggcaaaagaa aaatcatctg agttaacagg tattgcaaaa gaaaaagcgc aaggtctttc
     9181 tcaacaagca ggggatctag caggcaatgt taagcagaag gtaagtgaat cagcagagga
     9241 agcaggaagt gaatcagatg atatcttgtt aaacctcaaa gaacaatcag ctgatttatc
     9301 taatcgtttc aaaaaaacag cagaagatct gaaaaagcca gcagacgaat taggtagtat
     9361 tgctaaagat acttcagaag atatcatgat cgatgtaaaa gatgctgcag ataaagcagg
     9421 agagacggtc aatgaaggaa tgtcagaagc aaaaccagtt gcagatgaca caaaagaaat
     9481 gttgaaaatg gcaaaagaag atgcaaaaga agctaaaaaa gaaatgaaag atacaatgac
     9541 agattcgact accaatcact aagattactc atttctagaa taaaaaaggt gagagcggac
     9601 cagctctcac cttttttatt ttcattactc taaaacaagt aattcttttg gtgtagtcgt
     9661 gaatggcaca caaccatcac ttgtcacata cacacaatct tcgatacgta cccctacttt
     9721 ttcaggaata tagattcctg gttcaagaga gaagcacatc ccttcttcaa tcactaagtc
     9781 gtttccttct acaagagaag ggaattcgtg gacggttgtt ccgattccgt gacctaaacg
     9841 gtgattgaaa tattcgccgt agccatagct gttgatcacg tttcgtgcga tttgatcaag
     9901 ttcacctgct gtcacacctg ggcgaactgc ctcttgtgcg gcaagctgtg cttcaagagt
     9961 gatgttatag attttttctt ggaactcagt tggtttttga taagcaactg tacgagtagc
    10021 atcactgcaa tagccattcc aaataacgcc aagatcgaat aacactagtt catttggtga
    10081 aaccttcgtg cttcctggtg taccatgagg gcttgcagca tttgctcctg caaggactaa
    10141 tgtgtcgaaa gacatttgtg aaacaccttg tttttttaat tggtattcga tttctgcgat
    10201 aattgcttgt tcagttacgc cttcttttac tgttttgaag ccaatttcaa aggcaacatc
    10261 ggcccattta ccagcttcga tcagtttgtc tttttcttct accgttttga tcagttgcag
    10321 acgctggata atagaagtta gatcggtgta agaatctgta cctgtcaaga tatcagagat
    10381 agcatcgaag cgatcgacag tcagagcatt cttttcaata cctacattac caggttgccc
    10441 atagcgtgcg cgaagctctt ttccgatgat ctcccaagga ttttcgctgt ctaagtagcc
    10501 acgtacatcg tacgcccagc tgctgttttg agcatcttca acttccagag caggagtgaa
    10561 aaggaaagga tcttgttcca gagggataaa aagagctagt acacgctcgt gaggatcact
    10621 ttcatatccg gaaaagtaag cgatgtggcc agggtcgctg atataagcca attctacttg
    10681 gtgttgtgcc atccattgac gtagttcatt gatttttacg ttattcattt ggcaacctac
    10741 tttctaaatt aattttgtat tcaataattg taccactgat tgattaaaag accaacgttc
    10801 ttaaaactga aaaaagtaaa aattttcatg aaaacagaga taaaacggtt gcaattgttg
    10861 agattatttg atatcctatt ttagaaatgt aagacgtatt ttcagaaaac atataaaata
    10921 tgaataggag aacacaaatg gaaaagcaaa caatcactat ctatgatgta gcgagagagg
    10981 caaatgtttc gatggctact gtttcacgtg tcgtaaatgg caatccaaac gtcaaaccag
    11041 caacaagaaa aaaagtcttg gaagttatcg atcgcttgga ttatcgtcca aatgcagtcg
    11101 cacgtggctt ggcaagtaag aaaacaacaa cagttggggt aatcattcct gatgtcagca
    11161 atatgttctt tgcctcttta gcacgtggta tcgacgatgt ggcaacaatg tacaaataca
    11221 atatcatctt agcaaactca gatggcaacg atcaaaaaga agtcaatgta ttgaataatt
    11281 tattggctaa gcaagtggac ggcgtgatct ttatgggtca ccatatcaca gacgaaatcc
    11341 gtggagaatt ttcacgttca aaaacgcctg ttgtactagc tggttccatt gatccagatg
    11401 aacaagtagg tagcgtaaac attgattatg tgtcagcaac aaaagatgca gtaaataaat
    11461 tagcaaaaag cggcaataaa aaaatcgctt ttgtcagcgg tgcgctgatt gatcctatca
    11521 atggtcaaaa ccgtctaaaa ggctataaag aagcattaag cgaaaacaat ctaccatata
    11581 gcgaaggatt gatttttgag gcacaataca actttaaaga tggtctgtct ctagttgacc
    11641 ggatccataa tagcggtgca acagctgtct atgtttcaga cgatgaatta gccattggta
    11701 tcttggatgg tttattagac cgcggcgtaa aagtaccaga agaattcgaa atcatcacaa
    11761 gcaacaattc tttactgaca gaagtagctc gtcctcgttt gacaagtatc acacaaccat
    11821 tatacgattt aggagcggta tccatgcgcc tattgacgaa aatgatgaat aaagaagaag
    11881 tcgaagaaaa aacgattatc ttgccttatg gaatcgaaga aaaaggatca actaaataat
    11941 aaaagatcaa tcatttaaag gttgttccaa aagtggtcaa cttctggaac aacgtttata
    12001 cgagaaaggg ggttatgaca aaattttgtc ataacccctt tttttttgtg actttaaaaa
    12061 aagagaaaat ggcggaaaca aaccttacgt ccatcgtata cgacacaatc tgtgcgtaga
    12121 tgctacattt tgttcactac tatcaaaatt actttaaaat gaaaacgtga taaaaaagaa
    12181 agtagaaaag tagataagta actctaaaaa atccaaaaaa atccaggctc gattgcgtac
    12241 ttatcttaaa ggagaaacaa tccatcatat ataacccgaa aggagacttc tatttgccta
    12301 agaaaagacg aaagaccata gtcatcattt tgaccattct tactatagga atcggaggga
    12361 aattttacat ggacaaaaga gaaatgcaaa gacagaaaga tttactcgca gtagaaaaac
    12421 agtccgtcaa agttctgaaa aatacctttg cggatatcaa ggaagtgaag attgaaaaat
    12481 ctgctcgaaa tgaaatgacg ggttcatacc ggatagttat tctaatgact aataaacaag
    12541 atcaatcgat ttatttttct tatagttttt ggaaagaaag aaatgagata ggaagttacg
    12601 gaatagttga tgaaaaaaag caaaaagaag gaaatacgct caataaagtt aaagtaactt
    12661 actctaatgg aaatgaggaa agtatttaat gattactgac aaacaatata gtgaattaag
    12721 tgatgctgtt tactggctag atcctaaaca tagagactat gtacctgaaa tgcaagaaaa
    12781 tttaagtttt aaaattaacg gcactatgta taaaatccta aaaatcaaaa actccttcga
    12841 cggcatgcag gcgatggctg tagcgccaat cgtccatagc aaattggaga aaaatttcaa
    12901 aaataaaaaa attcctgcaa actttcgcgt acttaaataa tgaaggtgtc aatacttaca
    12961 taaaaagaaa ggaggcacgt tcttgtcaag gaaaataaga aaactcagct tagccatttt
    13021 attaatcgtc atattaggga tcggagggaa agtctatatg gacaaaagag aagcacaaag
    13081 gcagaaagat ttactcgcag tagaaaaaca gtcagtcaaa gttctgaaaa atacctttgc
    13141 ggatatcagg gaagtgaagg tagaagaatt taaaaaaaac cctgttaccg gaagttatgg
    13201 tgcacttgtg acaatgacaa ataatgaagg gaaatctgtt tattttgatt atagtttttg
    13261 gaaggagaga aatgaacttg gtggttttgg cattgagaac agagcggtac aaaagacagg
    13321 agtcactata aaaagagtaa aagtaatttt ttctaacgga caggaggagt tagtatgaca
    13381 ataaacgata agcattacaa tgatattagt gagaaggttt attggctaga tcccaaatat
    13441 ccccgctaca atgagggata caaaaagaac tctgttaaag aatttgctgg tatggaattt
    13501 caaatcctac aaatcaaaga ctcattggac ggcatgcagg cgatgtctgt agcgccaatc
    13561 aagaacggta aagtggatct ttctcaagta gtgattgctt ttgcaggaac gaacttaagt
    13621 gattggaaag atttggaaac ggatgcaaga agtatcatga atctctacgg gaatagacca
    13681 ggagcaagtt tttctgaaaa agcaacaaca aacaagattt tatccgttag tggattgaaa
    13741 acagcggggc aaatcaattc agcgattgca tttgctaatg aagtaaaaaa ggaatatgga
    13801 gaagctgcta tttctactac cggccattca ttaggtggat tcttagcatt atatgtagca
    13861 gcagagaaac aatggaaaaa tgtcggcttc aacgggccgg acccgtatga tctcttatca
    13921 ccagaagcaa aaaaatgggt ggaagaaaat cccggtatgc tcaccaatta ccgaaatcac
    13981 gccgatttta tcggtaattt tggtggtaat ggcacaggtg ctgaagttcg gatcagtatg
    14041 gaaacagcat tcttgaatct gcttgcttcc cacagtttaa cctcttggaa gtttgatgaa
    14101 aatggaaagc tgattattcc tgaaaatgaa aacaatgtta aagctcgaaa acaacagaaa
    14161 gaaaaccaag cgacccagtt gttttcctat cagttgcaag aactgaacaa catacgtaaa
    14221 aaactacgat taagtggcgg ccggctgaca gttaatgaac aaatttactt agatgacaca
    14281 caagctaggt tagtagtgga aaagttatcg gcaaaaatga aaagcgctat ggaagaagtt
    14341 atccgcatca atcaaagagg aatttttgag ctagagaaaa aatggcaaga aggcttgcgg
    14401 caagcacgtg ttgtagcccc ttcgttgact gaacaggaaa tcatagaagc attagctagt
    14461 gtgggcgcca caaaagaaaa cttagtcgat tctgcgaaag aagtctatct gctacgaatc
    14521 aataaggcaa gacgtatggg ggaggccttt gatacattgg cgaaggagat ccaagacaaa
    14581 atcaatgaaa tcgtggcacg agatcgagaa ttagcacagc aattcaatta aaggagaagt
    14641 agatgaaact agaagaattg gaaagagatt atcgaagtga acgaagacaa ttagaagctc
    14701 aagaagatga attgatccac tttaagaatc aaggattacg attgatggag caagaggagc
    14761 agcgactgca tcatgtatta aagaacttag ctttagataa tgagcctctg tttcaagcaa
    14821 gacgaagtta ttcgaattat caggagcatt atcaacaagc cctacaagta gaacgacgaa
    14881 aactctatca gcagcaagat gaactagaac gttcctatcg tcaaaaaatc agacaaataa
    14941 ctatggagaa atcatcttat gaatgaattt ttaatgcaat tactaaaaga attagagaaa
    15001 aatctacatc gatcaaatgt acgttcagtt ggtatgggga tatctcagca aatttgggca
    15061 gaaaaacgat tgacagatca aaactaccaa atgactgcag aagaagctgc tcaagaattt
    15121 tctaaccgac atgtacactt gaaaggatca gtaaaagggc aatttgcaga aaaactaact
    15181 gaattattcc aaagacaaga aaagaaatta aaacagtttc gttagtaaag ttatatagaa
    15241 aaattttgtg aaaatggt
//
LOCUS       DBBGRF010000064        15134 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000064 DBBGRF010000000
VERSION     DBBGRF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.064"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(172..627)
                     /locus_tag="ACIZD4_002418"
     CDS             complement(172..627)
                     /locus_tag="ACIZD4_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991302.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(781..1989)
                     /locus_tag="ACIZD4_002419"
     CDS             complement(781..1989)
                     /locus_tag="ACIZD4_002419"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGC5991303.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2101..2433)
                     /locus_tag="ACIZD4_002420"
     CDS             complement(2101..2433)
                     /locus_tag="ACIZD4_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HGC5991304.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2581..3456
                     /locus_tag="ACIZD4_002421"
     CDS             2581..3456
                     /locus_tag="ACIZD4_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGC5991305.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3538..4119)
                     /locus_tag="ACIZD4_002422"
     CDS             complement(3538..4119)
                     /locus_tag="ACIZD4_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HGC5991306.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4125..5384)
                     /locus_tag="ACIZD4_002423"
     CDS             complement(4125..5384)
                     /locus_tag="ACIZD4_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGC5991307.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5386..6432)
                     /locus_tag="ACIZD4_002424"
     CDS             complement(5386..6432)
                     /locus_tag="ACIZD4_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991308.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(6667..6942)
                     /locus_tag="ACIZD4_002425"
     CDS             complement(6667..6942)
                     /locus_tag="ACIZD4_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGC5991309.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(7185..8495)
                     /gene="der"
                     /locus_tag="ACIZD4_002426"
     CDS             complement(7185..8495)
                     /gene="der"
                     /locus_tag="ACIZD4_002426"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGC5991310.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(8677..9890)
                     /gene="rpsA"
                     /locus_tag="ACIZD4_002427"
                     /pseudo
     CDS             complement(8677..9890)
                     /gene="rpsA"
                     /locus_tag="ACIZD4_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
     gene            complement(10025..10705)
                     /gene="cmk"
                     /locus_tag="ACIZD4_002428"
     CDS             complement(10025..10705)
                     /gene="cmk"
                     /locus_tag="ACIZD4_002428"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGC5991311.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(10754..11389)
                     /locus_tag="ACIZD4_002429"
     CDS             complement(10754..11389)
                     /locus_tag="ACIZD4_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGC5991312.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(11455..12858)
                     /locus_tag="ACIZD4_002430"
     CDS             complement(11455..12858)
                     /locus_tag="ACIZD4_002430"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HGC5991313.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(12845..13876)
                     /locus_tag="ACIZD4_002431"
     CDS             complement(12845..13876)
                     /locus_tag="ACIZD4_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991314.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            13907..14128
                     /locus_tag="ACIZD4_002432"
     CDS             13907..14128
                     /locus_tag="ACIZD4_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGC5991315.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(14293..15030)
                     /locus_tag="ACIZD4_002433"
     CDS             complement(14293..15030)
                     /locus_tag="ACIZD4_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HGC5991316.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
BASE COUNT         4205 a         3205 c         2572 g         5152 t
ORIGIN      
        1 ggttcattct gacccagatt tgattttgta caacccatca gtccttattg acaaagagcc
       61 caaaaatctt gtcacagtcc cttattctga ataaacggtg tggaagagac agcctatcag
      121 tagtaataag acacatctct ttcacagcct catttttgcg taaaaatcga tttattcgaa
      181 aaattccccg tatacatctt ctacacgttg atctggattg atcacgatat acaagttacc
      241 tgttttttcg ctgatttttg ttgattgata ttgattgtct aatccttctg ttcctttatc
      301 tagatatggg aagtacacaa gatcaggtgt gccatttcgg taaaggattt ccattcgctc
      361 gatatcttcg tatttcaatg cgcgattaaa catgcccatt tccagtccgc ctaggttgat
      421 atcatgtgtc gcaactgcgt ccccttcatg gaagatttcg attttaaatc cagcacacgg
      481 atggatttca acaaattcac tgccattgat tcgtccaaaa cttgttgtga tttgtttgat
      541 ccaaagatcg ccgatatgac ggcggttgat cgtccaggtt tctccatttc taaaataaaa
      601 ttttagcgct gtcatttctt tactcattaa aaagactcct ttatgatgta atttattctt
      661 gtactacctc agtttagcac aaatttatgt aagtggtcac atcttatgtt ttttcttcta
      721 atgacgtatc tgcccacttt aagtagccaa caaagctgag cagatacagt ctagtgtttt
      781 ttaaatcaat ttttctttcg ataaaaaatc caaaacctgt tttttatcat tttttattct
      841 ttgttctacg acggcttttt cagctaattg caaagcttca ctaacccact taccaggttt
      901 ttttccagtt tcttctagca agattttacc atctactgct aattcgctta atgacttgat
      961 aggtaaacga tcataggatt ctcctacggc atccatctga ggtgtttcgt caaaatagat
     1021 catcaattct tctacttgca gtgcatgttt tttgcctaag aagtacaatt cgaatggttc
     1081 caaagctcca gtttctcgtt gtcgtagtcc ttggacaagt gcttgaacgt ctttaatcat
     1141 ttggttagaa cacttccacg atttcaaaaa ggaacgaatc tcattttctt ttagatccag
     1201 ttggctgatc aataatgccc atgcttggct ctcttctttc aatgggacgg atggtaattc
     1261 agcaaaacgt aaaagtgctt cgccttcttc tttcaaaccg ggacagcaaa tgtagcactc
     1321 tgtttcaata aatgcatgga ttcccgcggc ccgttcattt cccaagagca tcttgatgaa
     1381 ttccacattt atacgttcta cagatatttt acctaatagc tcgtggtttt ctttgatggc
     1441 gtagaaggtt tcttcctcta atttgaaccc tagttgactg acaaaacgca acccgcgcat
     1501 cattcgtaag gcatcttcat ggaaccgctc atgaggattg cctacagctc gcaagatctg
     1561 ttcttctaga tcttgcagac catcgaacaa atcgatgatt tctccatctt ctttcaaagc
     1621 aaacgcattg atcgtaaaat ctcttctttt caaatcttct gccaacgaac gaacgaattc
     1681 gacatgatct ggtctacggt agtcctgata agttgattcc gtccgaaatg tggtgatctc
     1741 atattgttca tcattttcta ataccaacac agttccatgt tcgatcccaa tatctatcgt
     1801 ttttggaaaa agctgtttga tttcttctgg aaatgcgctt gttgcgatat ccacatcatg
     1861 gattggctgg ttcagcaaga tatcacgaac acttccacct acaaaataag cttcatatcc
     1921 tgcattctct aattttttca gaactggaat tgccttttgg tattccagag gtaattgttt
     1981 taatttcatt tttccaacct ttcctgcgtg tttcttgtcc tgagataaag actcagttgc
     2041 atggtgactg tttgacaagt ccgtttcaga gtcttcaagg ccaggaccac ttcatcttgt
     2101 ttactcgtcc ttacgctcaa agcgattatg gtctctttga ttgaattttt ccatgttttt
     2161 ttcaaaaact tcagttaagt cgatattcaa tgaattagcc atgatcatcg taacgaataa
     2221 aacatcacca agttcttctg ctaccgagtt aactggttca gaagcctttt tgcttttttc
     2281 tccataagtg tggttgactt ctcttgccaa ttcacctact tcttcagtta atcgagccat
     2341 ctgagctaat ggagagaaat accccacctt gaattgctgg atatattcat ccacttcctg
     2401 ctgcatactg tataaagaac gctttttatc catctttttc cctccaaaac tatcttacca
     2461 aaactttaac gcaaatccta gataagagca attgagaaaa tcgaatttcc atgctacatt
     2521 taggaaggaa tttctaaatg gaaattctgt gaaaatacat aattgaaagc tggaattcat
     2581 atggtcaaac gaaaaacagt aaaagaagtt ctttttatca ttataggaac aagtatttat
     2641 gcatttggtc ttgtttactt gaacatcgct aatcatttag cagaaggggg agtctcaggg
     2701 atcaccttga tcttaagagc tttatttggt attgatccag cttatacgac tttattaatc
     2761 aacatcccat tgattttact aggaggaaag atcctcggta aacgttcctt ggcctatact
     2821 gttctaggta cactttcttt gtcattcttt ttatggatct ggcaaagggt tccactagaa
     2881 atcaatttac agcatgatct actgatcgtt tctctacttg cgggtttagt tgcaggtgta
     2941 ggaagcggga tcgtctaccg catgggtgga acaacaggcg gcagtgatat tatcgctcgg
     3001 attttagaac aaaattacgg catcactatg gggcgttccc tattggcatt tgatatcatc
     3061 gtcttacttg cttcattaac ctatatcgac ttgaaacgta tgatgtatac gttgattgtt
     3121 tcgtatgttt tcagtcgtgt gattgattcg atcttagatg gcggatattc tgcaaaaggt
     3181 ctacttgtcg tctccaacaa aagcgaagag attgcaccac tactgatgac cggtctgcaa
     3241 agaggtgtga ctttcctttc tggagaaggc gcattctctg gtaattcaaa aaaaatcatc
     3301 tatatggtcg ttagctctag tgaattaact gaagctaaga ggatcgtcca cgagattgac
     3361 gaaaaagctt tcctttcaat catcaatgtg catgaagtgg aagggcaagg ctttacttat
     3421 ttgaagccac agacaagatt actgaaaaaa ctataagaaa aaagacaaag ataggctatg
     3481 aggaaagatt ccacatccag ctgacctttg tcttttttag tactatacta tttttaacta
     3541 attgttatgt tcacttaccc ggttactttt cttttgtgtc tgcaaaagga tctttcggtt
     3601 aacttcatca gataatttca aaaaagcatc cctatctcca tcttctagtg cttgatcgat
     3661 ttgagcataa agcattttta gttttgcctc ttcttctttt tcttgaaaat atcgttcaat
     3721 taattcagta tcttcttcac tgactgaaga atcccaagaa gaaaatggat tgtcttctaa
     3781 gatagataga tattctcttg tctgccaagc attttcgaat atacattcca catataaagg
     3841 ctttttccaa ttcaaacgga tttcatgaaa aatctggtct gtgtccgtaa attcttttcc
     3901 ctgcaaaaac aatttcatgg gttccccttc aacagataga tcactgatct gcagtcctcg
     3961 atccgcaaaa ttcgcccctt caacaaagtg gacattgctt aaaatcgctt catgattggc
     4021 aagataattc aagatccaaa aaacttctct tcggctaaaa gatacatgat tgaccatcca
     4081 cgttaaaaaa ttcttctttt cccgtacatc aattagcatt tttctcacct ctctgttagg
     4141 tcatctaata atgacagtgc ctccatatct cctggttcaa gtgttaaata ataagtcaat
     4201 aattcttgcg ctcttttcag ctgcccttct tctcttaaga aaaaggcata ctctttcaag
     4261 aaatctggtt catgtgatag ttcatgataa gcctgttcat agtgtacagc tgcaacggta
     4321 aagtcttcta attcattata agcatgggct aggttccatt ctgcataagg attagcagtt
     4381 tcttccatct gattgatcac ttgtatcaca tcttcatatc tttcatcatc caagtaaaga
     4441 ttacttaaag taagtaatgt ttcatcttgt ttgtctccta cttctaaagc tttcagtaaa
     4501 agttcttctg ctcgctgtct atcatgcaga cggaaagcat tttccgaggc caggtgataa
     4561 agttcgactt ggtaaggatt ttctttgatt ccttcttcta acactgtttg tgcttcttca
     4621 atcatttctt cttcttgaag agcttgtcct agatatagat ataacgattg ataatgcgga
     4681 ttaacttctc gaagttcttc cagatagttg attgcctgct gattttcttt caattgaaga
     4741 ttcgtaaaag ctagctggaa cagtcgatca tctgtccttt cttctttcag tgcttcttct
     4801 aaaggtacga tagctgcttc gaattctcct tgcatactta aggattgtcc taaacgttcc
     4861 tgcatcgaga ttcctgaaat ttcatttatc ccgcttgcca acaatgtttc ataaaccact
     4921 gctgcctctt tgaaacgatc aactgaaaaa tacaattcag ctagcgcaaa ctggatcaat
     4981 ggttcatcag gaagcaaccc agctgcttct ttcaattttg cttcactcac ttcagggatt
     5041 ccgataactt ggtacaaatc agctatcgcc aataagcttt gcggatagta atcactttgc
     5101 ttatccactt tttccaggta ttcaaaagct aagtcgatct cattatcttc gattgcaatt
     5161 tctgctaacg ggatgttcag tccgtcattt tctgggtatt ggttgatcag ttgttcaaaa
     5221 atctgttttg cttcgatcaa aaagccaata gccagcaatt cttcgcctag ttcagctaat
     5281 atatctgctg ggtcttcttt taatgctttt tctaaaaaga tttgtgcttg tgacaagtct
     5341 tcatctgata aagcttgcaa cattttttcg ctatttgtat tcatttcaat tccctcttat
     5401 ctcactgacg atttgttgaa ataccgtcat tgttctcaat aattcttttt cgtttggatg
     5461 ttggtatccg tctattatac ctattttttc taaaacaagt atttttttgc ttttttctgc
     5521 caaaaaaaga actttttcca aatactccat ctttgaaatc tgttccagcc agtggattgg
     5581 atagccaagc aagtccagcc acacaaaaaa gttttttagt tggaaatcaa aaggatatgc
     5641 ttggagattc cacacgaaat gaaacatcat tcctaaaaat tttttcatac tagcagaaag
     5701 tagatggcca ttttcggtca gataaaaagc ttgttcaaac agtttaccat aatttgacag
     5761 gttttctgcc tctaattgat aaaaatagat catttcttcg atcatcccgg caaacggccg
     5821 agtcgttaat tgctttttat ttggatagtt tttatacaga ttttgcaaaa aacgatgatc
     5881 acaaatcatt ccgcaacaga taaaagtcaa aaagtcaatc tgctttccgt ccacctgccg
     5941 ctcgctgatt gtttgatcat aaacgatgcg ttctggcaga ttgatggttt gcagcactac
     6001 acgatttggt agctgcaaaa tcgtccgctg cggtgttaat gctcggctta gagaacggat
     6061 cgatacaggg atcatccata gtgatgaatc aagggttgta tgtttttgaa aaaaacctgc
     6121 cagatccatg atcccttcat ttccaaatcc gatgataaac atggattgat tttcgggata
     6181 gcgtttgacg aaatcaagca ggttctttaa ttctgttaaa tgattgcatt gagtgttggc
     6241 acaaatatac cagtcattgt ttgcttgatt tgcaaataac gggttgatct tatctgcaaa
     6301 caaatcataa tagcgctgat tcgttaaaaa taagattggc tgatcaatgg aaagttctct
     6361 tagctgactg actagcgttt ctccgtaaaa cactttcgtc aacgcatctt ctacttgata
     6421 atcaagttcc atacgcatcc ctcctcttct tatttttatt ttaccattag taagcaaatt
     6481 ctagaaaaga taagagcaaa gctcacctca taacttggaa ataaataaaa attaaataaa
     6541 atacatgtgt tttctatgta tgacatacgg attcggaatc tctgtctctt atttattcct
     6601 tttctgctag gaaataaaaa gaaaagcact tgtagcccta gagccacaag cgctttttca
     6661 actgtcttat ttaacagcgt cttttaatgc tttacctggt ttgaatgcag gtactttgct
     6721 agctggaatt tcgatttctt caccagtttg tgggttacga cctttgcgag ctgcgcgttc
     6781 gcgaacttca aagttaccaa aaccgattaa ttgaactttt tcgccgttag ctaaagcatc
     6841 ttgaatagtt gaaaatacag catctactgc tgcagttgca tcttttttag ttaaatcagt
     6901 agctgaagca actttttcga ttaattctgc tttgtttgcc atggatagat tcacctcctc
     6961 cacaagagat atgatagaaa tatcatttag ttaaaacttt ctgagtggtc cagaagttta
     7021 aaaagaaata ttgattaact tcaatattct gttatcacga tatcatatga accgcttaat
     7081 agcaaggttt ttaccaattt tcacatgctt tttttagtca tagaaacgta acaaacgaaa
     7141 ctgtcttttt cttttgaaaa aaaaacgtcg atatggtaaa atgcctattt tctcctacga
     7201 gggataattc ggatggacgt cccttcaaaa gtaaatgctt ttctgatttg attttctaag
     7261 aaacgttcat aagaaaaatg catcaattcc tcttcattga caaaaacgac aaatgtaggt
     7321 ggtttgacag cgacttgtgt agcataaaaa atcttcaggc gttttccttt atctgttggt
     7381 gttggattga ttgctacagc atccataatg atatcattca acacagccga agagatacga
     7441 agattctggt tcatacttac ttgttcgatc atttcaggca gacgttccaa ccgttgttta
     7501 gtcactgcag aaacaaaaac gattggagcg taatcaagat accggaattc atcacgaatc
     7561 tcttgttcga aatcacgcat tgtattggtt tctttcttta caagatccca tttattcacg
     7621 acgataataa ttccacgacc agcttcatgg gcgtaacccg ctactcgctt gtcttgttcc
     7681 cgaatccctt cttcagcatt cagtaccatc aaaacgatat cagaacggtc aatggcacgc
     7741 attgcacgca tcacgctgta tttttcagta ttttcgtata cttttccgcg tttacgcata
     7801 ccagctgtat ctatcattaa gaatttctga ccactttcag aaacgaagtg ggtgtcgatt
     7861 gcgtctcggg tcgttccttc aatatccgaa acaattacac gttcttctcc taaaatcgca
     7921 ttgatcaaag aggatttacc aacatttggg cgaccaatca aactaaactt aatcgtgtcg
     7981 tcgtcctctt cttcagtctc ttcagagaaa tacttcactg cttcatctaa aatatcacca
     8041 atccctagtc catggcttcc tgaaacagga taaggatcgc ctagccctaa ggaataaaat
     8101 tcatagatat cgtttctcat ttctggatta tctactttat tgactgctaa aatcactggt
     8161 ttattacttc tgtataaaat tttcgcaacc atctcatctg cgtctgtcac gccttcgcgt
     8221 ccgctgacta cacaaatgat tacatctgct tcttcaatcg cgatttctgc ttgatgcttg
     8281 atctgatcca taaaaggttc atcgccaaga tcaattccgc ctgtgtcgat cacgctgaat
     8341 tctcgaccta accattcacc ttttgcataa atacgatcac gagttactcc aggagtatct
     8401 tcgacaatcg agatacgctc accagcgatg cggttaaaaa tcgtagactt accgacgttc
     8461 gggcggccaa cgattgcaat tgttggattt gccatattat ttcctcctca caagtttcca
     8521 atctcactta gtttaacgaa tgcattgcca actttcaagc atagattgtc aattaaacga
     8581 agtattttta ttccttattg aaatactaat cgcttttcaa aagaaaaact gagacaaaag
     8641 cagctgcttt catctcagtc acagatacaa aatcaattat ttttcagaat catcggttgc
     8701 tttttcttct acttcttctt tcaacgcatc acctaaaatg tcgtattttc ttctggtaat
     8761 tcataagact caacattttt tggttcttct tctgaagctg gtttttcttc taaagctttg
     8821 atactcaatg caatacgatg ttcttctgga tggatctcta atactttcac tttcacttcg
     8881 tcaccttcat gaagcacttc atgtggtgtc gcaatatgtt tatgtgaaat ttgagagata
     8941 tggactagcc cttctactcc agggaacact tcaacaaagg caccgaagct tgtcaaacgt
     9001 ttaactgttc cgtctaatac tgtgccaact ggagcttttg tatcgatttc tgaccaaggt
     9061 ccaggctgtg tgtctttgat tgacaaggaa acacgttctt gttcaggatt gatagacaac
     9121 actttgacat ttacatcatc attgacagcc aatacatcac ttggttttgc tacatgacta
     9181 tgtgaaatct ctgagacatg gactagaccg tcaattccgc ctaggtcgac aaatgcgcca
     9241 aaatcagtaa gacgtgcaac acgtccactg agaacatctc cctcatggat agttgaaaga
     9301 atttcttttt tcttttcttc tctttcgttt tccactaccg ctttatgcga taagatcaaa
     9361 cgattttctg atggttcgat ttcgatgatt ttaaagctca atgttttgcc tttatagtct
     9421 gaaaagtctg caacaaaatg atcttccacc attgatgcag ggacaaaacc acgtacaccg
     9481 acgtcaacga ctaaaccgcc tttgacaaca tttgtaacag gtgcttcgat gaccttgccc
     9541 tcttggaaat ctctttcgat atcttcccaa acttttttag catctaaacg gcgttttgaa
     9601 agtaggtagc tgccgttttc tttatctttg ccgatcgtac tgataacgac taaatctaat
     9661 acatcaccga cttttactac ttcgctgata tcttctaccg gcaaagttga taattctttt
     9721 gccggaacga ctccttcaac tccagcccct tcgattccga caatcacttg tttgtcttca
     9781 atgactaaaa cttcgccctt aacaacatcg ccaactttta cttcttgtac gcttttcatt
     9841 gcgtcttcca ttgactggtt gttctcttga ttttgatcaa attctgtcat aacacttgtc
     9901 ctcctaacca acattctgcc gtaagtacgg tactgttttt agtttaattg attattcaaa
     9961 aaaaataaag cgatttcgtt cgttttcctt gaaaaaacaa ttgtttttca ttttttttct
    10021 taatttaaaa aagaagataa ccttttttca aaacaacagc ttttattgct gcaacgactt
    10081 ctggaatcga tttgccagtc gtatcgatac gaacagcatc ctctgcttgc ttcagcggag
    10141 agacgtccct tgttgaatca taatggtctc tttcctgtat ctctttcgtc agtgtttcaa
    10201 gatcagtcgg aattcctttt tcttggttct ctttgaaacg tctttctgca cgctcactta
    10261 cgcttgctac taaaaagatt ttcacttctg cattcggtaa tacagctgtc ccgatgtctc
    10321 ttccgtccat gacaacgcca ccgcgttccc ctatttttcg ttggacagca actaattctt
    10381 ctctgacttt tccatgtgca gagacttcag aaacagcttt tgtgacatct ggttgacgga
    10441 tttctaaagt cacatctttt gatgctatga atacatgctg tccatcttct tgttgcgaaa
    10501 aagagatagg atactttttg atcagcgaaa ctagcccttc ttcatctgaa aaagatacat
    10561 tgttcgtaat agctaaataa gttactgcgc gatacatggc accggtatct gtataaatat
    10621 aattcaattc ttttgctaat atcttggcaa cggtactttt cccagatgaa gcaggcccgt
    10681 cgattgcaat actgatttgt gtcatgatat aactcctttt tctcagaaaa aaagccgcaa
    10741 agcgcggcta ttattattta attcttaatt cttgaccagg gtaaagcata aagttgtttg
    10801 gatctaagcc attcaattca aacaattgat cagtggtgat ccctgcacgc tcagccactt
    10861 gttttggacc ttcgcctgct tgaacagtcg ttgttgaacc ggctgcagct gatgaagaag
    10921 gtgttgtttc tgctgcattg ctgcttgaat cccctgcttg ataagttgcc tcacttgagg
    10981 aagtcggtgt tgtctctgct gcaatactgc tttctgacgt tacacctgta tcttgagaca
    11041 cagtagattc ttccgcgatt gtactagatt ctactgttga agtctcagtt gactcctctt
    11101 ttgttgtact tgtagaactt tctactactg atgtcgaagt ttcagaagaa gttgctgctg
    11161 ttgcattgtt gcttgatcca tttctgatcc agaaataagc acctgctgga atagcgatac
    11221 ataagaccag taaaatcaaa aatagcgaaa gaaataatgt atttcctttc ttttgttgtc
    11281 tctgagaact tcttgatgaa acttcatcat ctgtatcgta gattggttgt tcccatggtt
    11341 cttgtgtttc gttattttct gtagattgat gtctatcttt tctgctcact gttttacctc
    11401 ctaaactcta tcgtgtgtat tataccatag gaaaaagtgt cttgtcctaa aaaatcaatg
    11461 ttccatgttt tttttaaata aatttagtaa aatcgtttcc caatgaagtt gttcagtctt
    11521 agaaaaaagc ttcctctttg gcagaagttc tgcttttgct ccatcaatat cacaacaatt
    11581 ctgcggcttt tcggagagtt tttcgccaaa ataagctaag atgaattttc tgcggcagtt
    11641 ttcttcatta atatagcgaa gcatctgctg caggcggaat tctttttctt tttcctgacg
    11701 tttgagccgt tccacccaat tttctggttt ttcagactgc tggatcagct ccatccattt
    11761 tttttgcagc tcatcaaagg gagcttgctt tgtggcatat tccaaataaa gctcaaaact
    11821 ttgtcgctgt tctctagaaa gttgattaaa gaaataatgg atacgttcat ccccactttg
    11881 ataaaaaaga attgctgcac tttcttcctg atctctgcct gctcgaccga tttcttgtac
    11941 atagttttct agactgtctg gcaaatcata atggaccaca taacggatat cagatttatc
    12001 gatccccata ccaaatgcat tcgtagcaat gagaaactgc agctgatttt ttacaaactg
    12061 ctgttgaagt tgtcttcttt gagctgcatc aagaccaccg tgatagtatc caactgtaaa
    12121 acgttccctg aataaatgat acaatcgttc gacttctttt tttgttgcac aataaatgat
    12181 tgccgctcct tgtgctcttt ccatgaagtg ttcaagttct tgttcttttt gctgcgtttt
    12241 ccgaacaaaa agcgagatat tttgccgatt gactgattgt ctgatctctt ttggtggtcg
    12301 atcaaatagt acatgacgta tatctcttgc tactaaatct gttgctgtcg ccgttagtgc
    12361 cagtgtgacc gggtttccta aaagctttcg gatttttcct aactgttgat attctggacg
    12421 gaaatcaact ccccattgag acacgcaatg agcctcatct actacatata acgcaatatt
    12481 ttgttttttc agatgctcta aaagagaagg attagtcaac atttcgggac tcaaaaacaa
    12541 aaatttatat tgcgatagat gacggaggac gtatcttctt tcagattgcg aaagtaaact
    12601 attgaaagca gctactcgtt tctcccctcg tttttgtaat tgcgtcactt gatcttccat
    12661 tagagaaagc agcggtgaca cgatgatgac cagaccttcc attaaatacc ccgtcaattg
    12721 atagcaaagg ctttttcccg ttcctgtagg caaaatagcg agagtatctt ctccatcaag
    12781 caacgcctga ataatttctt cttggccggg acgaaatgaa tcaaatccaa aatatttttt
    12841 taattcattt attaacattc tgtatcgctt cctttctcaa tagatagatt tgatacaaac
    12901 gaaattctcc ataatctaat tgtccatcta cattccattc gctaaagcgc cactctcgca
    12961 cggaatcctt atttggttcc aaacgttcga ttgtttctgc agagagaatc cactcgtatg
    13021 gaaaatcatc aaaaaacaag gcccactcaa taagatgatc tgttactgtt cctcttttta
    13081 aatgacggat tgccatgatc tggtcaattg tctgaccatt cataaacatc tgcttggtga
    13141 tcatcatgct ttgattgaaa ttttgctgta ataatgaatc gatcaaagcg tgccaaagcg
    13201 aatctggccg tttttcgatt tgtgctaaca aaaggtggat acatctgctt tgttgcagat
    13261 aaacctctga ctcatcattg ttttttgcca gctgataagg aagcagccct gttcgctcat
    13321 ttccagataa ttggttagct aaaaaatctg ctgcttcttc tggtatctcc gaaaacagct
    13381 gcaccaaact ctcatacgca gtatcaatta aaatttcacg tggcaattgg ctttcactaa
    13441 gccatttttt tagttggaaa gtataaaaag gacttgtctc tgctggaaga tagtcttgaa
    13501 tacccgttgc cagattagaa attacttgaa cagcaaattt aatgagccgc caactagttt
    13561 cccctgttct gccatagcgg tcaaaacgca aaccagtatg ttctatttga tgttcggaca
    13621 acatatcagc ccctgcaggc gttagctttg cttcattttc atttatttcg atccaacctt
    13681 gctgcgcaat tttttgcaaa atttgataaa acttatcctg cttcaattct ggaaaactgt
    13741 tatggataaa caaaagttcg tgggtaaatc cataaataag tactgaagtc gttcgttttc
    13801 ccacaaggag ttggtaaaga gaactaatcc gcagcttgtg tcctgatgaa aatagcgata
    13861 aaataaaaac aatcatatta ttctccttaa gttaggatgg ttagaaatgt cactactatg
    13921 taaacttgta cctgaacgct gtattgcatg cggtctttgt caaatcgaag cgccagatat
    13981 tttcgattat gatgaagaag gaatcgtttt atttgcccaa gaaccagagg ctcatcaaca
    14041 gttcgtgatg ccggaagaag aaacatatgt aaaaaaagcg tatcaaaaat gtccagttcg
    14101 agcgatttta ttagaaaata aaatataaat ataaacgaaa ctttaaaaac gtacactaag
    14161 ttctctaaac ttgaaaataa gccgggatct gtttctcttg ttccgtgaaa tcccgactta
    14221 ttttgaaaga ttcatttgct atctatagtt aattgactag ttttttcacg gaccctatag
    14281 gacccattta tattatttca actttttcag ccagttttcc aatgtattga cgatcacagt
    14341 ttgctggtct gcgttagaaa tttctgcctc tccatctcct ttttgctcac catagctgcc
    14401 aaaacctcca tgatttccgc cattgattga tacatactct gttctttccg gtaaatactg
    14461 cttagcttct tgataagctt cctgattcaa tactttatct tttgtcgccg tgatcgataa
    14521 aacaggaaca gctgattctg tcaatgttcc ttttttgtcg ggataacttg ccatgaagaa
    14581 tacccctttt aaatgtttgt ctgaatgatt cttattgaca taacgacttg ccattacgcc
    14641 acctaatgaa tggccaccga tcacataatc ggaatttgga aaatcttctt tgaccttatc
    14701 cgctttgttt ccgcccatca ctgctagatc aagtggcatt ttgacaatag cgactgaaaa
    14761 gccgtttttt gctaaatctt gcgcccaaat actataactt tctggctcta cgagagcacc
    14821 aggataaaaa ataagtaatg gagactttcc atgattcttt ttctctcctt caaaaaataa
    14881 gtaatcttct ttgttttttc cttcttttac caacacttgc gcttctgacg atggttcgta
    14941 cgtattttgc tgtatatagt aataaccggc tccaccgagt aatcctaaaa tgatgactaa
    15001 gccaattagt attcgtctaa atattttcac tttctcccac cttttctatc tgagtgaccc
    15061 ctttttctta atcaagtatg attatacctt aaaaaaataa gagagaaatg caaactttcc
    15121 agcatcaaat aaaa
//
LOCUS       DBBGRF010000065        15078 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000065 DBBGRF010000000
VERSION     DBBGRF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15078
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.065"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            80..688
                     /locus_tag="ACIZD4_002434"
                     /pseudo
     CDS             80..688
                     /locus_tag="ACIZD4_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            708..1736
                     /locus_tag="ACIZD4_002435"
     CDS             708..1736
                     /locus_tag="ACIZD4_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HGC5991317.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1733..2491
                     /locus_tag="ACIZD4_002436"
     CDS             1733..2491
                     /locus_tag="ACIZD4_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HGC5991318.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2577..3317)
                     /locus_tag="ACIZD4_002437"
     CDS             complement(2577..3317)
                     /locus_tag="ACIZD4_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HGC5991319.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3378..4631
                     /locus_tag="ACIZD4_002438"
     CDS             3378..4631
                     /locus_tag="ACIZD4_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGC5991320.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4926..5180
                     /locus_tag="ACIZD4_002439"
                     /pseudo
     CDS             4926..5180
                     /locus_tag="ACIZD4_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5302..5628
                     /locus_tag="ACIZD4_002440"
     CDS             5302..5628
                     /locus_tag="ACIZD4_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HGC5991321.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5696..6409
                     /locus_tag="ACIZD4_002441"
     CDS             5696..6409
                     /locus_tag="ACIZD4_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HGC5991322.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6719..7571
                     /gene="licT"
                     /locus_tag="ACIZD4_002442"
                     /pseudo
     CDS             6719..7571
                     /gene="licT"
                     /locus_tag="ACIZD4_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
     gene            7692..9557
                     /locus_tag="ACIZD4_002443"
     CDS             7692..9557
                     /locus_tag="ACIZD4_002443"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC5991323.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9571..11017
                     /locus_tag="ACIZD4_002444"
                     /pseudo
     CDS             9571..11017
                     /locus_tag="ACIZD4_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            11125..11826
                     /locus_tag="ACIZD4_002445"
     CDS             11125..11826
                     /locus_tag="ACIZD4_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5991324.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            11952..12464
                     /locus_tag="ACIZD4_002446"
                     /pseudo
     CDS             11952..12464
                     /locus_tag="ACIZD4_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(12862..13071)
                     /locus_tag="ACIZD4_002447"
     CDS             complement(12862..13071)
                     /locus_tag="ACIZD4_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HGC5991325.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            13312..13887
                     /locus_tag="ACIZD4_002448"
     CDS             13312..13887
                     /locus_tag="ACIZD4_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HGC5991326.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            13887..14327
                     /locus_tag="ACIZD4_002449"
     CDS             13887..14327
                     /locus_tag="ACIZD4_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HGC5991327.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            14343..15044
                     /locus_tag="ACIZD4_002450"
     CDS             14343..15044
                     /locus_tag="ACIZD4_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HGC5991328.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5087 a         2501 c         3179 g         4311 t
ORIGIN      
        1 aaacctccag acttcttgat agctcaagta tatcttgagg tgcatttgtt agtaaggtac
       61 tgttctatgg ggcgcttacc cagaaaatca actttttgca ggagatgtat tagaaattgt
      121 attaaacgac caagcaggag aagctgctgc taagggtgtg cagaacaagc caagtaccaa
      181 cgatgaaatt gggaatcaca atccaagtga tacgccagtt gtttatcatg atgccccgcc
      241 ttttgcacct gctacgaaga ttgtagtaga aggtggtctc tcatttcttg ccccttccaa
      301 actcgattgt ggtcagatca aagcaactgg gttgacgcaa gaagcatttg gccaaatgga
      361 tatacaggaa aaattatgga tttatgatca gcgagaaaca aaaagtccat ggatcttaac
      421 gataaaatta tctcagcctt tcacaaccga tgcaggattt tctatgcagg atgtcctata
      481 tttcaagaaa gctgaggagt atcaattagt gaatgaagaa gaactggaaa ttgtcagagg
      541 acaaaattca acgaatgtgc aaacagatta ttcagaatat ttaaataatg gtcgggcgtt
      601 taaacttgtc ttaaccaaag aaaatcagat agctggtaat tactcagcag agatgacatg
      661 gacattagca gatgcgccga cagaataaag atcaaggaga atgattgatg aatcgaatat
      721 ggaataaaag tcatcgaaac aactgctctt tacttctgat ccttctcctt ggattcatcc
      781 tttggcagac acctgtccat gcctccgaat tcaattttgc ggtagatttt gaattaccgg
      841 ctaatcagat tgataagaac aaaacatata taaatgtaag gatggagcct gggaaaacac
      901 aggaaatccc ctacacggtc tttaaccgaa cagataaatc agtaacagtt gagacattga
      961 tccactccgc tacgacgaat tcaaacggtg tgatcgaata tggagaatca aaaagtaaat
     1021 ttgatgaaac attaagttat gatatgaaaa acttagcaaa aacagtggga gaaataactg
     1081 tccctcctca aagtgcggtc actgagacac tttcactgaa agctccagaa aaagagctgg
     1141 ctggtgtggt cgcaggagga atcacgtttc aagaaaaaaa agagaacgtt tctaacaaaa
     1201 gtacagttgg tgtcgtcaat cagttttctc aagtgaaagc aatcttgatt cgaaatagcg
     1261 aaaaagagtc ttccccaaat ttgaaattaa aaaaaactta tgcggatcaa agcgatggaa
     1321 gaaatgtgat taaggcgaat cttcaaaatc caaatgcttc ttatatgttc ggcttgacta
     1381 catcggttga aatctacaaa aaagaaacaa aagagcctta tctttcaata aaaaaagaaa
     1441 aaatagatgt agcacccaat acaaattttg atttacttgt cccattagaa ggaaaaaaat
     1501 tagctccggg acattatcaa gcggttgtga agggtgcttg gaaagaaaaa cgctggaatc
     1561 tccataccga ttttgaaata actgatgatg cagcggacca attgaatgaa aaggatattg
     1621 atttaaaaaa tcagccagaa acatttgact ggcgatggct gatacttgtt ggagtcattc
     1681 ttattggctt atttgctgga ttatttattt taaaagaaag aaggaaaaag aaatgaaaaa
     1741 aacaattgca ttaagtaccg ttctagctgg aagtctatta ttatgtacac aaagtgtttt
     1801 tgctgagaat aagagctcag ccactacaga aggaacgatt tctgtaacaa aaccagatgc
     1861 cgcaaatcct gaagacgttg ttccagttcc tcctgttgat ccaaatgatc ccgatacgcc
     1921 gtttacacct aacgaaccaa atcagggaac atccggatta ctgacgattg accaagctcc
     1981 agatcttgat tttggaacaa tcaagttagg tacagcaaaa acagtatatg ctgcattaca
     2041 aaacggaacg gacagtacag ggacagcaac acaagtacag aatttcgtac aagtaacgga
     2101 taaaagcgga atttatgccg gttggaaact atcagtcaaa cgaacagaat ttattggtac
     2161 aacatctgat acgaataaac taactggttc aaaggtgaaa ttcaaaaacg ccgtgattcg
     2221 aaatagcgca actaatagca gtggaacgcc atctactatt tctggtactg gcgctgaagg
     2281 aattgagatc ccagcagatc aggcagtaga tctagtaact gcaggagcaa atgaagggat
     2341 tggcacatgg atttattcat taggagagaa tgtggaacaa gggagacaat cagtggaatt
     2401 atttgttcct gtatccaatt atgccgtaga caactacgtt tcaacattca catggtcgtt
     2461 aacagatgct cctacagaag ggaaagcgta aaatcaaatc aatgacttca gggagtggag
     2521 ccgattcaag gccaactccc tgaaatctgc tatgcttacg tctcagctct tattcatcaa
     2581 ctcgaagcag ttttttggaa gtcatggaaa cgttcctttg tcttttcaaa gatctttcga
     2641 ccaacgagta aggagtcacc attgaaaaat tctaacacat aatgagcaga atcaattttc
     2701 tgcaattgcg ataagttgat acagtaagat tttaatagta aaaagtaagc atacttttcc
     2761 aactctgtct tcaattgttt taaagaagta ttcactaatt tatcttctgt agttgttttg
     2821 accataactt ggtttttcaa acctttgata ctttcaatat ataaaatttc ccgaggatac
     2881 aggacgagac ttccaccttt ttgatcaata aagattttat cgacatttac gatttgctgt
     2941 tctttccaat tgatctgttc tagcacttga cgaatttgtt cagataaatt cctgtctttt
     3001 ctgatatatc caatcggaag gattttccga ttgatgatct ctactgcaaa attcgtataa
     3061 gcggtgaaaa aaacaatatt actatgtgca ttttttttac gtatttgttc ggcgacatca
     3121 atacctgtga gtgattgctt caagtcgata tcgataaaga aaacatcgtg attatcaata
     3181 gtacccaact ggatcaactg attgatttga gagatagaag tgagctgcac gatattctcg
     3241 atatgatgat tgaccaattc tttgatgatc cattcgctgt gaaactggtt atcttctatg
     3301 ataaaatact ttttcatatg caggctccta ttaaaaaaat atgtgtacat tttgaaacaa
     3361 aacaatggag gaataagatg gtcgcaacag tgacacttta tttgaccttt actttgattt
     3421 tagatttagg tatctattta ttcttttcga aacaactgct agtaaaaaac agctttggtt
     3481 ttatagcttt gatggtggtg acacttttat ttcctatccc taaagtgagc tttccttacc
     3541 tagttggctt attattgatg tttctttttt attttactac gaaaaacctg tttatcagct
     3601 gtttgatcag taatcttttt tttgctatca ctggactcag cttttttctg gtttttgatc
     3661 tgatggatta tttaggaaag agacatcttg gaacagcaag tttttttgca ctacttatcg
     3721 catttatttt ctatctatta gtaaaaagta tagacaaaca gacgagattt ctcaacttgc
     3781 tttttactta tccaactgaa cactattttg gaggtatttg tattttatta agctggggcg
     3841 tgatttactt ggtattggga agtgttcact tccgctcatc taattatctg cttctatctc
     3901 ttttgtcgat agtcatcagt tttttttctt tgtttttttc cattatgttg atcagtttcc
     3961 aagtaaaaga aagacaacat caggaatcgc ttcaactgta tcaaataaat gaagaatatt
     4021 accatcatct agaggaattc aaacatgatt ataaaagtct actgttttca ttaaaaatta
     4081 ctcttcagga aaataaaaaa gaaacgttgg aatttttaga aatcttagaa gatcattctg
     4141 cagctatttt tgaaaaaccg caaatacaac agctaacaaa tattgtatcc ccagctgtca
     4201 ggggtgtctt tttaaaattt ctagaaaaag cagaatcgga gaaaatcccg atccaagtag
     4261 ttattcctgt cgaagtgaaa acaatcccga ttgatctggt tgtttttatt cgctgtttat
     4321 ctatttttat ttctaacgca ttcgatcatc gtgtagccga tcagagtccg attacgatca
     4381 atctgctgga agaaaaagag ggattacgtt ttagtatagc gaacaaggca aatccgacga
     4441 atttgacgct atcggagatg gtcaaaagag gaaaaacctc taaaaaaaat ggcgggttag
     4501 gtctatacag tgcgaaaaaa atgttggatg tttacgaaaa tgcagaacta aaaatcgaat
     4561 tttcaaaaca gaatcactat ttttttgtag aaatgtatct ggcatctaga aagagcaaat
     4621 cagcctactg acttactgtc aaaggataag cttgaggaaa gtctacacgg agatagagac
     4681 aacaacacag catattcaaa agaaacagaa gcgtgatgac cgttgtcacc cttctgtttc
     4741 ttttgctatg tagttaaaca aagtagttga cacttccgct acttagtatt agtacgaaag
     4801 tatacttcat gatactaagt agataagaag tgaaaagcgg aacccacgat cgtcaaaatg
     4861 ctaactgctt tgcttacacc agataaaggg aagagcaata tcgcttattt taggcgtgga
     4921 gaagcaagaa aatccctacg atcacacaaa aaatgctgac ccagcagtta agagagttag
     4981 aacaagatgg cattgtccat cgaaaagtct ataaccaagt cccgcctaaa gtagagtact
     5041 cgctcaccga agaaggaaaa tcattaagag agattctagt agcgatgtct gtttggggag
     5101 aagaacgtat cgaaaaacaa aaagcctcag gggaagaagt cacattactg catacacatg
     5161 gtggctacct aaattactga tttctatgac atttatttta aataaaagaa aacaggagtt
     5221 tttttaaaag catcatctat tttttatgta aaaaaatggt atgattaatc aagtaagaaa
     5281 tgattggaag aaggcaagca aatgaatagc atggaaaaag ttaaccagtt tagagatgaa
     5341 cgtaattggc gacaatttca taacgaaaaa gatttggcta tttctatttc tttggaagca
     5401 tctgaattgt tagaactttt tcaatggaaa acgccggaag aagtaaaaga aacacaatta
     5461 gaacgaatca aagaagaact ggcggatgta ttgatctatt catacatgat ggcagacaac
     5521 cttcagctgg atctagatga gatcattgaa gaaaaattga tcaaaaataa tttgaaatat
     5581 cctgtagaaa aaagcgcagg tgtacgaaaa aaatacacag agttttagaa atgtgtcatt
     5641 cggctgttgg aaagagcaaa agaaaaacag taaaatgagt ctggagggag agaaaatgaa
     5701 aaaaaaagga aaagcaaaaa gatggctagt caatatcctc ttgttcctct tgttattagt
     5761 aggactagct ttgattttca atgaacagat caaggattat cttgtcagag agacaggaga
     5821 taaatatgct atagcgaatg taacaaaaga agatctgaaa aagaataacg ataaagatgt
     5881 cagttttgac tttgatgcgg tagaaccaat gacgacagaa ggggtcatga ggtcgcagat
     5941 gagaggaaca gatctaccag tgattgctag tatcgcagtc ccttcagttt caatcaattt
     6001 accgattttc aaaggcttgg ataatacgtc actactttac ggagcaggaa cattatctcc
     6061 agatcaagaa atgggaaaag gaaattatgc cttagcaagc catcgtgcaa cgaaccctga
     6121 attgttgttt acaccgctgg aaaatttaga gatgggtgcc aagatctatt tgacagattt
     6181 agaaaatgtg tatacataca aaacattttt taaagaaaaa gttgctccta cagataccca
     6241 attactgaat gaagtcgagg aaaaagaaat tgtcacacta attacttgtg gcgacatgga
     6301 cgccgtcacg cgactagttg tacaaggaga actggaaagt gttacaccga taaaagatgc
     6361 gacagatgat atgagatctg ctttcaatct agagacaaaa acattttagg atactgggac
     6421 ataagtcgtt acagattaaa aacagccaaa ggatatgaat cgataaggaa aaaccaattt
     6481 gctgaaaaaa agaggaacgc aaagaggtgc atctctgatt tggttgtttt ctagatagac
     6541 ttgtgttcca gtttttttat tttttatatg aaaaggcttg cataaataaa aattcgatgg
     6601 tatgatgatt ttgaataaga aatggattgt tactgtacgg caggcaaaac cagaattcag
     6661 ctaagaaaca gtaggcgaat tctaggtttt tttatttttc ttgagagggc gaagcaaaat
     6721 gaaaattgat aaaattttga ataacaatgt cgtcatttcg aaaaatggat tcggggaaga
     6781 agtcgtttgt atgggaaaag gactagcttt tcaaaaaaaa gattggggac gagatttcgc
     6841 cagaagcggt ccaaaaagaa tttattttaa gagattcttt tgctaaaaac caattccagc
     6901 agctgatggc tgatattccg gcagaggaga tcgaatgggt caaacaagta gtcgaactgg
     6961 ctgaagataa actaaaagtt gaattttcgc ctaatattta tctgacattg accgatcatc
     7021 ttcattatgc gatcacacga gcaaaagaaa atatccaact gcctaatcca ttattatttg
     7081 aaacaaaaaa attttatccg aaagaatatc aagcagcgaa agaggctctt ttgttcgtga
     7141 aacaaaagac gggtgtggaa ctttctgagg atgaagccgg ttttattgcc tttcattttg
     7201 tgaatagcca acaaggaaac gaagacatgc aagtgacgat gaccgctacc acaatggtaa
     7261 gagatatact gagtatcatc agtaaattct tcggcatcgt gttcgatgaa gaatctttga
     7321 attatcagcg tatcattact catctgcagt tttttgccca gcgttatctc aaaggggaag
     7381 gatctgacga gcaagatgaa tttctctacg cattagttca aggaaagtat ccaaaagcgt
     7441 ttcattgtgt cgaacggatc aatgagtatc ttcgacaaac gcaaaaacag gaaatgggga
     7501 tcgcagagca gatttattta acgattcata ttcaaagagt agtaagtgag aaaaaaagca
     7561 tccaatcata aggattgtta ctgtatggca ggcaaaacct ggattgaaaa aataggttca
     7621 cgaatgtttg tgactgtttt tttcaatctg ggtttttatt ttttaaataa aaaagaaaga
     7681 aggaaaaaac aatggataat caagcagttg gtcgtcgtgt atgggaagcg gtaggaggac
     7741 aaaagaatgt caaaagttta gtacattgtg ctacgcggtt gcgattcaga ttaaaagatg
     7801 aatctttagc agatacgcaa aagttaaaag aagacccgga cgtgatccaa gtcgtacaaa
     7861 gtggcggtca gtatcaagta gtgattggca gtaatgtagc agatgtttat caatcgatcg
     7921 tggatgagga aggtcttgca gtttcggagg atggaaaaga agagtccaaa aatattttga
     7981 atcgtctgat cgatattatc tctagtatat ttacaccttt tctaggggcg atggcagccg
     8041 ccggggtatt gaaaggattc ttatcattgg caacggtgat gggctggctg acagctgata
     8101 gcggtactta tcaaatattg tttgctgcag cagatggtgt ctttaccttc ttacctgtca
     8161 tgcttgcttt tacagcagct aaaaagttca aagccaacca gtttttagca gtagcaattg
     8221 ctatggcact tgtgtatcca gctatcacag cagttgctgg tgcgggagaa gctatcagtt
     8281 tctttgggat cccagtgatt ctttcaccat ctggttatac ttcttctgtc ataccaatca
     8341 ttctagccgt atgggttcaa agtaaattag agccattcgt aaaaaaagtg attccgcaat
     8401 ttctgcaaat gattttagtt ccgcttgtcg ttttagtagt gatggttcca ttaacatttc
     8461 ttgctttagg accaatcggg acggttgccg gtaatgcttt aggcggtctc ttcaactcga
     8521 tttatggatt tagtccaatc gtagcaggtc taatcatggg aagtttatgg caagtattcg
     8581 tgatgttcgg catgcattgg ggattcgtac cgatcatgtt tttgaatatc gaacaatatg
     8641 ggtttgatgt attgatgcca atgcttcttc cagccatctt ggcacaaggt ggggctgctt
     8701 tagctgtagc attgcgaaca aaagatacga aacttcgagc attagggatt tcttctacag
     8761 tgacttcgtt atttggaatc actgaaccaa ctgtgtatgg tgtgacatta cctttgaaga
     8821 aaccattcat tgccgcttgt atttctggag gtattggtgg agctattatc ggattttccg
     8881 gagtaaaagc tttctccagc agtttggtca gcttattgac gattccgact ttcattaata
     8941 cggtggatgg tgtagagtca aatgtgacag tagcagtaat agctacagga attgcttttg
     9001 ttcttgcatt cgtaggtaca ttgattttag gatttgacga acaaacacaa gacaatcaat
     9061 tagaaaacaa acatgcgaat gcaggagaac cgattacttc agcacggcat accttaaaaa
     9121 gtcctttaac gggtaaagta ctgccattga gtgaagtacc agaccaagtt ttttcttctg
     9181 gcgtgatggg aaaaggtatc gctattgatc cagaagtagg agaactagtt gcacctgcag
     9241 acggagagat cacgactatt tttccaactg gacatgctgt agggatcaca acgactgacg
     9301 gagcggagat tttgattcat atcgggatgg atacagtaga attaaatggg aatggctttg
     9361 agatcttagt caaacaaggg gatctcgtca aagcaggaga tttattgatt cgttttgaca
     9421 tcgaagcaat tagagcagct ggctatagcg taatcactcc agttgtcatt acgaatactg
     9481 atgcatttgc cgatatactt gaattagacc aaaaagagat tattgcaaac gaagatgttc
     9541 tggcaattgt aaaataagga ggaaatcagg atgcaatcac gtttttcaga aaaattttta
     9601 tggggtggag caactgctgc caaatcaatt agaaggggct tatgatcgag acggaaaagg
     9661 actatccgtt gcagatgcta tgcctggagg taagcagcgc tttgcgatta tcggcagtga
     9721 agaatttgac tggacgattg atcaagaaaa atatatttac ccgaatcatc gaggaatcga
     9781 tcattacgat cgtttcaaag aagatcttgc cttgtttgcg gaaatgggat tcaaatgtta
     9841 tcgtttttcg attgcctgga cacgaatttt tccaaatgga gacgaaggta ctcctaacga
     9901 agcgggatta gaattttatg atcagctgat tgatgagtgc ttaaaatatt atgatattga
     9961 acctgtgatc acgatttctc attacgaaat gcctcttcat ttggcaaaag aatacggtgg
    10021 ctggaaaaat cgaaaactga tcgacttcta tgaacgattt gctcagacag tattagagag
    10081 atacagcagt aaagtcaaat attggatgac tttcaatgaa atcaattcgg cctttcactt
    10141 tccagcttta agtcaaggat tagtaaaaag caatggagca ggagagtacc aaaatatttt
    10201 ccaagcatgg cataatcaat tcgttgcaag tagcaaagcc gtaaaaatcg gccacgaatt
    10261 gcgttcggat atccaaatcg gctgcatgat tatctatgca acaacttaca gcatcgatgc
    10321 caatccagtc aatcaggcag caacaatgat ccaaaaccaa gaattcaatt ttttctgcac
    10381 ggatgtccaa gtacgtggag aataccctgc atacacagcg cgtacccata aaaaatatgg
    10441 agtcgatccg gaaaaattag agcaaacgga aaaagacttc cagttgctaa aagaatatcc
    10501 agtggactac atcggattta gttattatat gtctacggca atcaatgaga ctgatccaca
    10561 agcagcaact tcagaaggga acttgctggg aggagtaaaa aatccgtttc ttgaggcaag
    10621 tgaatggggc tggcagatcg atccagaagg gctgagaatc gcattgaatg aattatacaa
    10681 tcgttaccag aaaccattat tcattgttga aaacggtctt ggagccattg atcatatgga
    10741 agaggatggc acgattattg atgattatcg gatcgattat ttacgtcgtc atatcgaagc
    10801 gatggctaat gcagtagcag acggtgtaga tttgatgggc tatacgcctt ggggatgtat
    10861 cgatcttgtc agtgcatcaa caggagaaat gagtaaacgt tacggcttta tctatgtgga
    10921 tctagacgat gaaggaaatg ggacactgaa tcgatcaaag aaaaaatctt ttgattggta
    10981 taaagaagta attgcctcaa atggcgtaaa cttgtaatta aagcagctga atgaaaaaga
    11041 acacacttct cacatgtgat ttgtgttctt tttttatttt ttatgtgcta ttcttttagt
    11101 aatagtaaag caaagggtga cgttatgaaa aggacacgtg tactatactt ggaagtcgca
    11161 gataaaatta aagaagatat tttctcagga aaatatccag tcggttcgat gttgccgaca
    11221 gaaagtgaat tagaagaact gtttcaagtc agcaaaatca ctgtccgaaa ggcaatcgaa
    11281 ctgctggcat cagatgaata tgtcgcaaag aaaagtggtc gtgggacgac ggttctaagc
    11341 aatcgtcctt acaatcgatt atccaaagcg gcaagcttta cgcaaatctt ggagaactcc
    11401 cgatatgaag tccggaaaga aacgctggat ttgcaattgg tccatataaa gaaggaagat
    11461 cctttgtttt cctttttcgg tgagcaagct gtttgtttta agcgcttata ttatttgaac
    11521 aatcagcctt atatttattt tgttcattat cttccacaag aaatgatgca attcagcaga
    11581 gaagaatttg gcaaagaatc tttgtatcgt ttgctgacga aaaaaggata tactattgac
    11641 tcattttctg atgatttctc ggcagtattt ttaacagaag aagaacaagg aattctgaaa
    11701 acagacgcac agatcggcat caaacggata cggaaatcgt ctacgcaaat tggggaaatg
    11761 attgaatatt cggaggcggt ctaccatacg gagctgcatc cttaccatat tgattatgaa
    11821 acataaataa aaaaagaggt tgtgaaaaag ctgccctgca tcaagtaata agaacagcca
    11881 aacaaaaata gcttctcata tttttcgttt ggttaggctt attaccgcag atacacggct
    11941 gtttctggat taccatttat tctggataag ggggtgtggc acgattttca gaaggaatct
    12001 atgaaccaat cactgtattg attttagctt cgatggtaac cccattcggc ttgacgatcg
    12061 cttatttctt agggaaaatc attcgtaaaa atatactcaa tcgtcaagaa atcgatacat
    12121 tgaagaccgc ttttcctatg gggatctgtc agatcacaga gggatgtttc cctatcgtat
    12181 tgaacgactt ggcacgcaat gtcatagcaa cgggagtcgg tgggacagta ggtggcggat
    12241 taagcatgtt ttggggcgca gatagccgta ttccggcatc gggaatgttt gcagtcgcta
    12301 cgatgaccag accatgggca ttcattggtg cattgttagc tggttctttt gtcacaggaa
    12361 taaccatttt attattgaaa aaaccagtag atccgaatgc agaaatcatc caagaagaaa
    12421 aagaggaaga agacatatct tgggatgatt tgacaattag ttaggagagg cagaatggat
    12481 tacaagaaaa aagtacaata gatgtacctt gagacaggaa tggtatgaaa gaatcagagt
    12541 tagaaagaat cgaatataca gattttggtt taggagcgat cgaaactgtc cagagcatcg
    12601 gcaccctcct tgaaatgacg atgaaggaaa aatgagaacc tttcgttgtc gaaagggtct
    12661 ggtatacctt atgtcgaagg aaaggaaaca aaaaaacttt cctgtactat tccaaaaagg
    12721 aaagaaagtt attatacagt aaaaaaagaa attattcttc atgctagaga tcagtacacg
    12781 ttcgagccca atatcaaaca ctagttccag gcaggcgcaa caggtgcggt tatcactgaa
    12841 ttttcttcca gcagtgacga ttcaagtgat atttttacaa atccagctat ttatcgttaa
    12901 caaaaagatt tttaggagaa gctgatgaac aaaaatgatc aaattttgat cgtttagttc
    12961 gtcggctttt ttatttagag aaacatcatt tatcagtgaa acataacacg agaacaaaat
    13021 gattttttcg ttaataaaag aaacaagtat ttgttgttta aaataataca cgttattggc
    13081 atataggacg aaatcccagt atcttctata agtaagtcat ttcatatcga tgaaaacacg
    13141 ttatttattt ttgttttatc tataaaatgg ctgaaaaatg atttttttct aaatactata
    13201 tatagtggcg tctatcctat ataccactaa aaaactacaa aatctagtct tttattttaa
    13261 aaaaacacgt gtagaatgaa gatagacttt tgagttaggg agtgtttttt tatgaaactt
    13321 actgtttttt gcggttcccg ttttggtaat aaagaaagtt acaaatttat tgcgcaaacg
    13381 ttaggaaaat acatggcaca agaagaaatc gaactggttt acggtggttc atactccggg
    13441 attatgggag tgattagtaa aacagtactg gaaaataacg gaaaagtcac aggtatctat
    13501 ccgaatgggc tttttgaaac tgaattgcct ggaaaagatg ttactacatt tattcctaca
    13561 gaaacgatcg atgaaagaaa ggtattatta tttgaaaagg gagatgctgt cctcgttttc
    13621 cctggaggtc taggtacatt ggaggaattc tcacaacttc tttcttggat agcaatcggt
    13681 ctgacgcccg acaagccaat cggaatattg aatattggcg gttattacag cggcttgcaa
    13741 caattattag aaacttttgc aaaagaggat tttatggata aaaaatggtt ggatcaagta
    13801 atcttttcca acaatccatt ggaactggtc aatgaattac gagcagtatc tattaaaaat
    13861 cagttattat tgaaggaggc aaaataatga gtcaaatata tttagcagga ccattttttt
    13921 cagaggagca aatcgatcga gtaagtcgta tcgaaaaagc gttggaggaa aacaaaacag
    13981 tcacaagttt ctactctcca cgtcatcacc aagaaagcaa ttatgaacta ttcagcgctg
    14041 gatgggcgca ggaagtatac gaaaaagata tggaagaact gacaaatgca gaatttgttg
    14101 ttgctatcct tgactttgag catcaaacaa tcgatccagg aacggcttac gaattaggtg
    14161 tggcaactat gttgaaaaaa ccgatgatca ttgtacaaga agagacggta cctacgaact
    14221 tgatgattac acaaagtctc catacgtatt taaaatcaga ccaagctgta cgtgaatatg
    14281 attttgaaac attgcctgtt gaaacttacg taggcgagta cttatagaag aggaagggtt
    14341 gtatgtcagt gattttgatt tcaggaacga ttggtgcagg taagagcagt ttgacggata
    14401 tgcttgcaaa agagattgat tctaaaccat tttatgaaaa tgtcgaagat aacgaagtat
    14461 tgccgctctt ttattcaaat cctgagcagt acgctttttt attgcaaatc ttctttttga
    14521 acaagcgatt tttagcaatg aaaaatgctt tagtgaacga tgacaatgtg ctagaccgat
    14581 ccatctatga agatagcctg ttgttccatc taaacgctga tttaggtcgg gtaacggata
    14641 tcgaagtaca gcagtacgat agcttattag atacgatgct aaacgagtta gatgatgttg
    14701 ctccaaaaaa acggcctgat ttgatggtcc atatcaaagt ttctttggac acgatgctag
    14761 aacgtatcaa aaaacgtggg cgtgactatg aacagctaga aagcgatgag acgttatata
    14821 cctattatga aacgttgaac acccgctata atcaatggta tgaagatttt gatgtatgtc
    14881 ctaaaataca agtggatggg gataaattcg attttgtaga aaatccagaa gatgcaaaaa
    14941 aggtgatccg tcagatccaa gaaaaattag ctgaattgga aggaaagcct gctggaaaat
    15001 attttacgga taaccagcat gcaaaaggtc aagaattagg ctaaaaataa aaaaccaaac
    15061 gacgggaaag aaaaatta
//
LOCUS       DBBGRF010000066        14722 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000066 DBBGRF010000000
VERSION     DBBGRF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.066"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            4..978
                     /gene="bsh"
                     /locus_tag="ACIZD4_002451"
     CDS             4..978
                     /gene="bsh"
                     /locus_tag="ACIZD4_002451"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HGC5991329.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
     gene            1708..2025
                     /locus_tag="ACIZD4_002452"
     CDS             1708..2025
                     /locus_tag="ACIZD4_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HGC5991330.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(2229..2594)
                     /locus_tag="ACIZD4_002453"
     CDS             complement(2229..2594)
                     /locus_tag="ACIZD4_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991331.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            2802..3284
                     /locus_tag="ACIZD4_002454"
     CDS             2802..3284
                     /locus_tag="ACIZD4_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991332.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            3481..4371
                     /locus_tag="ACIZD4_002455"
     CDS             3481..4371
                     /locus_tag="ACIZD4_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HGC5991333.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            4696..7167
                     /locus_tag="ACIZD4_002456"
     CDS             4696..7167
                     /locus_tag="ACIZD4_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGC5991334.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7270..9006)
                     /locus_tag="ACIZD4_002457"
     CDS             complement(7270..9006)
                     /locus_tag="ACIZD4_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5991335.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9003..9707)
                     /locus_tag="ACIZD4_002458"
     CDS             complement(9003..9707)
                     /locus_tag="ACIZD4_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC5991336.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            9838..10341
                     /locus_tag="ACIZD4_002459"
     CDS             9838..10341
                     /locus_tag="ACIZD4_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HGC5991337.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10301..10639
                     /locus_tag="ACIZD4_002460"
     CDS             10301..10639
                     /locus_tag="ACIZD4_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGC5991338.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10660..12078
                     /gene="ffh"
                     /locus_tag="ACIZD4_002461"
     CDS             10660..12078
                     /gene="ffh"
                     /locus_tag="ACIZD4_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGC5991339.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12190..12768
                     /locus_tag="ACIZD4_002462"
     CDS             12190..12768
                     /locus_tag="ACIZD4_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGC5991340.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            12772..13293
                     /locus_tag="ACIZD4_002463"
     CDS             12772..13293
                     /locus_tag="ACIZD4_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HGC5991341.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(13372..13926)
                     /locus_tag="ACIZD4_002464"
     CDS             complement(13372..13926)
                     /locus_tag="ACIZD4_002464"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGC5991342.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14179..14454
                     /gene="rpsP"
                     /locus_tag="ACIZD4_002465"
     CDS             14179..14454
                     /gene="rpsP"
                     /locus_tag="ACIZD4_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGC5991343.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14466..14717
                     /locus_tag="ACIZD4_002466"
     CDS             14466..14717
                     /locus_tag="ACIZD4_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HGC5991344.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
BASE COUNT         4922 a         2529 c         2926 g         4345 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagtcact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgatgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aacatttttt cttgatgtga tatccttgtc ttttttgtaa
     1081 tgtttttaac ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg
     1141 tatattatgc tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac
     1201 ttaatccata gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca
     1261 ccccaaacca cttccccata agtgtattac gctttaaact cttttatatt tgaattcact
     1321 aagaagcata ccatattttt gaaaaaaagt gagaaaaaag gcttataatt aggatttaga
     1381 gtaattaatt agatgtttat tttataggac tgatattata gattacaaat agtatcgtat
     1441 ttcgcaatct taaaattatc ttcttactat gaataagata ataaaatttg tatttgtcct
     1501 ttttaggtaa cttattttaa tctatatacc tttctggatc aacgaaagta tactttatat
     1561 agtcataacg ccgatggtaa ctatgcactg taacgataat gctgctaaaa tatcttttta
     1621 cgaaaaacat cacaaggaaa aacttaacta tggtattatc taaacataat tttttcggta
     1681 tttaatattt aattaggagg gaatattttg cttttttata gtaattttat cttaatagta
     1741 gcgatattat tacttctgaa tatatggatt tttgatagga gtagaaatgc aagtataggt
     1801 tttagaacta aacgaagtct gtcttctaaa aaaaattggg tatactcaca aactattttt
     1861 tatggaggaa ttgttttaat tagtttactt tcttcaacac tttattcttt gaatattata
     1921 gatgtttcca cctcaaattc aatatctatt attggaatca ttattgctgc aattattaca
     1981 caactgtttt tagtgtttgg agagaagaaa agaagtaaaa aatagaaaaa ctagtgatag
     2041 ttttggtgat agtgatatta aaaatcagaa aagatagaaa aagcaggaga tagataaaat
     2101 gctgatattt cagcattttt taagagtata aaagagaaaa aaagtaataa atgtatacat
     2161 gatataagaa aaacatatat gtataaaaag aagaaagtag cttctctttg tacatatatg
     2221 gtttgttttt atggatgccg agctttttta taagataagg ctaccgccca taacgaccca
     2281 aggatttgtg gaactaagta aatacctgca agaagcaaga tcagctgggt cggttttaaa
     2341 ggatgataga agtaacgcca ttcagtaaaa ttggcgcaaa ataaatagga agtgacagta
     2401 gatataatat tggcaatgaa taaagatata atacgcctgt tcctttgaaa ataatatcca
     2461 gcaaaaagag ataaaaatat caatgtgatg aacccgctta cggaatgata acgaaaatca
     2521 agcagtaagg cgaaatgcac ataaggaaca aaagataaaa gcaacggaag gtttttccag
     2581 caagttttta tcatctttca tcaccaccta acaagtgtta ttattttgtt agttttattg
     2641 taaattgaat cctgcaataa tcaattactt tttcattatt tctagattaa atgaataaac
     2701 tctcatgcca ttatctctaa aaaaaaagtt tttcccccta atttttttag atagaaaatt
     2761 gtatagtatg atgagagaaa aagtagtttg ggggaacgtt aatgagaaga aaagcagtaa
     2821 tcgatcggct ttatttattt ttttggtttt ttcctatcgt tttgctacct tttacatggg
     2881 taaatgctgt tgtacaaggt gcggagatat taggcctgat ccaaggaagc ggatttgtgg
     2941 tttctaggaa ttttccagct ttgactgttt tctatttagt gataagtgta ggtctcttat
     3001 taccaaaatc tctgatcaat cactacaatt ggcagctgct ttacttttct tgcttattag
     3061 tatttacatc tatgttttct ttgctgcctc gcttgattat cggccctaat ggtttgagcg
     3121 agagtggatt gaaggattca gcttattcct ccatgtattt cttgacgatc aaaccatggt
     3181 tctatttagt aattgcctca tttattcttg caacattttt ttacttctgg acagaaatca
     3241 ggataaaaag tgaacgatct gtatctataa aaaataacta ttgatggtgg atcatcagta
     3301 aaaaagcata tgagctgcgt aaaatgcatg tttctcatat gcttttttta ttattatgta
     3361 aagaatgcga aaaacgttta catgattttt acataactta actatatttt tacagcaacc
     3421 atacgaggga tttacagtcg actgataaac tttagttgta aataagaaag gagcaataaa
     3481 atgaaaaaag tattgtttac tctaggtatg atgggaattc ttttagccgg atgcggctca
     3541 ggatcaggaa atacagatgg ctctgccaca caaaataatt caagtgactc aaatgaacaa
     3601 gtaaaaatcg ttgcggtagg ttcgacagca ttacagccgt tagtcgatgc agcacaagaa
     3661 agctttgtac aagaaaatcc aaattatcaa atctctgtac aaggaggagg aagcggaact
     3721 ggtttgagcc aagtcgaagc tggagcagtt actatcggaa actctgatgt atttgcagaa
     3781 gaaagagacg gagttgatgc ttcaaaatta gtggatcata aagtagcagt ggtcgggatg
     3841 gcgccaatcg tcaataaaga tacagatgtc aaagatatca ccaaacagga attgattgat
     3901 atctttacag gaaaaatcac taactggaag gaagttggcg ggaaagatca aaaaatcaac
     3961 gtcgtgaacc gtgcaaacgg cagcggtacc cgcgcgacat tcgaaaaatg gggactggat
     4021 ggtgctaccc ctgtgcagtc ccaagaacaa gattcatcag gaacagttcg gcagctggta
     4081 agtcaaacac caggagcaat cagctattta gctttctcat atctcgatga ttccacacaa
     4141 gcactaagta tcgacggtgt agaaccaaaa gaagagaatg tagcagataa cagctgggga
     4201 atctggtcat atgaacatat gtacacgaac ggaaaacctt cccctgaagt ccaaaaattc
     4261 ttagactaca tgatgacaga agaaatccaa gaaggacctg tcaaagaatt gggctattta
     4321 ccaatcacaa tgatggaagt agaacgtgat cacgaaggaa atatcaaata actagcagat
     4381 aaacatgcca cggtagtcgt tactattaag gaaaaatcaa ctatgtttcc cacatataca
     4441 tttttccttt aattgtgaaa aatagttcct catattttgc cgttttttga gctaataccg
     4501 agggtcagct gattaaacac cgtttattcg aaaaaaagag ctacgacata gaactgtcgt
     4561 agctcttttt ttgctatatg acaggaatga aaggtgtttg caagcttaat gtgaggaaca
     4621 ctttccatat ctgttctata ctggatagga gaagtttgga aatatccaga aaacgaaatc
     4681 aatcgaggta gccacatgaa gaataaatgg ataaatcgaa gtaaaaaaaa gaaagtaaca
     4741 caaagatcat cagataaagt catccgtctt tttccatcgt ataaagaagg attaacggca
     4801 gatcaagtca aggaacgaat agaaaaaggt gcagcaaata attcagtcga tcccacattc
     4861 aaaacaaatc agcaaatcgt attggaaaac atatttacgt atttcaattt gatctttctt
     4921 atcttagcca ttttgctttg tttagtagaa tcctataaga acttgacttt tttaccagtt
     4981 atcatagcca atacaggaat cgccattttt caggaaattc gatccaaaaa gatcttggac
     5041 gaactaaatg ttttaaatac agcaaaagtc aatgtcatac gggacgggat agaacaaaca
     5101 atagatatag aagaccttgt aatagatgac attgttattt tagagactgg acatcaaatt
     5161 ccagcagatg cagaggtcgt ggaaggaaaa ctgcaagtta atgaggcttt attgacaggc
     5221 gaagcagatg aaataaccaa agaaataggc gatccattaa tgtccggcag tttcattgtt
     5281 tccggaaaag cttacgcccg attagacaaa gttggagcag attcgtatat ttcccagctg
     5341 acagtcaaag ccaagacaat gggagaagga gaacagtcgg agatgattgc ttctcttaat
     5401 caattgatca aatggattgg gatcatcatt attcctatcg gtatcctgct tttttctcaa
     5461 agttactttt ttaatggaaa cacgatcaaa gaaagtgtcg ttgcaatgga agcagcattg
     5521 atcggtatga tacctgaagg actgtacttg ctgacgacga ttgcattagc attaagtgcg
     5581 actaaactag caaagcaaag agttctttta cacaatatga aaagcattga gacattggca
     5641 agggtaaatg tcctttgtgt agataaaaca ggaacgatca cagaaaataa aatgtctgtt
     5701 caaaaagtga tcgtctctaa aaaacaagaa ataatcagtc agtcagatca attggaagca
     5761 tgcattgctg actatgcaaa agcgatggca ggagacaatg caacaatgga agctgttaaa
     5821 gcatatttta caaaaaccac tgatcaatcc tatcaccatg ttattccttt ttcttctgtc
     5881 caaaaattca gcagtgtagc gttggcagac aaggtgtatg ttttaggagc gcccgaaatg
     5941 gttttgcgcg atcaattgcc ggaatatgcg gaagagtttg tttctttcgc tgaaaaaggc
     6001 tatcgcgtgt tggtctttgg tgtgtacgat gggattcttg aagaaccagt attgacagaa
     6061 gcagtcacac cattaggcta tattctgatt gctaatccta tcagaaaaga agcaagagcc
     6121 acatttgatt acttcaaaaa acagcaagta gccatcaaag tgatttctgg agataatccg
     6181 ctcaccgtat ccaatgtagc tgtccaagca gggatttcac atgctgatca gtacgttgat
     6241 gcatctaaat tatcagaaga agaatatgaa gcagctgtcg aaaaatatac agtttttgga
     6301 cgcgtcaagc cagaacaaaa gaaaatcttc gttcaattga taaagcgtaa caatacagta
     6361 gctatgacag gtgatggcgt gaatgatatt ctagccatga aagaagcaga ctgcagtata
     6421 gcgatggctt ccggaaatga agccgccatg caggcctcac aagtggtctt acttgattct
     6481 gacttttcac gcatgccaga agttgttgca gaaggacggc gcgttgtgaa caatattgag
     6541 cgatcagcca gcttgttttt agtgaagaat attttctcct ttttgctctc actgttttca
     6601 gtgatctttg ctctgaccta tcctttagaa ccatcacaaa tcacattgat tagtttgttt
     6661 actatcggac ttccatcttt cttgcttgct ctagaagaaa acaaaaagcg aatcagaggg
     6721 aaattcatca tgaatgtgat ggaaaaagct gtgccaggtg gactaacaga tatgatcgta
     6781 gtcggtgcgt tggtgatctg cggggtgact ttgaatctaa ataaaacaga tgtttctaca
     6841 gcatctacca tgcttttgat tgcagtaggg ttcctcgttc tctataaaat ctgttcaccg
     6901 ctgaataaat tcagaagtca gatcattctt ttctgtgcta gcggtaactt tttttcggtc
     6961 atctttttgc ataagctgtt ttcaatcacc ggtatctcag ctgtatcact tttgctgttg
     7021 agcattctat ttttctcggc agattcgatt tttaggcatt tgaccacatt ggtagaatat
     7081 ttgtttgaac gtaaaaatga aaaagagcaa aagccgttta gtcgcgtagc taaaaaattt
     7141 ctatcgatat ttaaacgaga aaattgacga aaagtatctc aaaaaagagt aaaaaagaac
     7201 aaccactcgt gtatctttcg aagcaggatg agtcatccaa ctttaaaacg cacgagcagt
     7261 tgctcttttt tacattttcg gaatggtaac ggtgaaagtc gaacctgttc caagatgact
     7321 gtctacagta atcgtaccat taaggagttg cacgtagtct tttacaatcg ctaaccctaa
     7381 tccggtcccg cctgaatgtc ggcttcgcgc cttgtctacg cggtaaaaac gctcaaagat
     7441 ccgttcctga tcctcaatgt cgatacctat accaaagtct tggacagaaa acgatagatc
     7501 atctgttgcc tgatagcgga taataatctc gctgtcgctt tttgaatatt ggacagcatt
     7561 ttcaatcaga tttttgataa ttggataaag gatatctgtt ttagtagtaa atggttcgtt
     7621 ctttccaatc aatcgaatcg tcaaccgttt cttttcgatg attggctgat aattttgaac
     7681 gatttgctgg aaataaggtt ctgtataaat tgtctggatc tcgtaagaat tctcgccatc
     7741 ttttgacagc tggatgattt cccgaatcag tttatctaac cggatcgcat ctttttgcat
     7801 gatctcaaga aaagaagtca gagtttgcgg gtcatctttt gcaccatcca gtaaagtctc
     7861 ggtaaaacca atcagtgaag tcacaggagt ttttaattcg tgagagacgt tgccaacgaa
     7921 atccttttgt agcttttcta aacgtcgcac tttcgttaag tcatacgcca cccctagaat
     7981 ctgtccggta ccttctgaat tagtaaagta gcgcaaactc aagtctaatg tctgccgacc
     8041 ttctgtaagg gtgatctcct gatggatcag cggatgctca ggagtcactt gatgaatcag
     8101 ctgaatgagt tttggctctt gaatgacttc tgtgtaccgc tgttcaggtt gatagcttac
     8161 cacgtttaaa tgtagctgca tctttggatt aagcagtagt aaacgagaat cagcatcatc
     8221 aatcaggaat acgccaatca tcagttcgtt cagtaacgta tataattgct cttctgtggt
     8281 agtacacgcc cgatacatct tactcatttg ttcgctcaac gcattaatcg tctgatacaa
     8341 ttcttcccat tgatcgggtg tttgcatgat tacttccgcc tgattaggat tttgcaccat
     8401 tttttttagt acgggcagca cggttttcaa tggctggttt ttttgataga tcagataata
     8461 gatcattcct gcaagaacaa ggaagaaaga cagaaagaag aaaaagaccc aacggcgaaa
     8521 actctcagtt ctcggtaaaa aaccgcttgt cggttctgcg atacgtaaaa tggcttctaa
     8581 ctggccactt tttttgactg gtaatgcgac atataaaaga tcctcattca aagtagtact
     8641 tttgcgcaaa gcgctaccta ggttcccacc attcaatacg gctttgattt cgggacggga
     8701 gtttcgctgt tcattcaatg tttcattgtt tgtgtcaaat aagatctttc cagtagcatc
     8761 cattaaagta atccgttcgt tcgactgatg gacgaattct tccaaagcag ttttgttttg
     8821 cgctgcttgg aggttttcga catctaattg ccggatcagc agttgtgctt tttttgtcag
     8881 gtagctttct tgctgttcca cgatctgctg ttgaaaataa tgggaaatca attgccagcc
     8941 accaaaaaac aaactaacta aaagaataag aaagaagaga cgttcataaa tttttttcca
     9001 tttcatcgtt ttggttcctg aaacttatag ccaaatcctc taatagtcac caagtacttt
     9061 ggatgttttg gatctcgctc gattttttct cgcaaatgac taacgtgtac atctacgatt
     9121 cggctttgtc ctgcgaagtc aaaattccaa atgcggtcta gcaatgtgtc tcggtcgatc
     9181 acacggtctt ttcgtttcat gaaataaaca agtaattcaa attctttcgg tgttagttca
     9241 atcagatggt cgtctacggt cacttgataa ttggtcaaat cagcagtgat ttgtccaatc
     9301 gatagatatt caggctcagc ttcatctttt gattgcttac gaggttcaat ccgtctgaat
     9361 attgctttca tacgggctaa tacttcgcga ggactaaatg gtttggtcaa atagtcgtca
     9421 gcacctattt ctaggccaat gatccgatcc acttggtcat ctttagccgt cagcatcaaa
     9481 atcggtgttt catttttttc ttgacgcagc cgctgagtga tctccatgcc atccatcgtt
     9541 ggaagcatca catctaaaat gatgaaatca aatgattgtt ctaatgctaa ttctaatcct
     9601 tcgcctccat ctgtggcact ggttaccttg tagccttctt tttccaaatt gaacgtcaag
     9661 agcgttacaa tagaaggttc atcatcaaca actagtattt ttttcattca aatctccttt
     9721 aaataggttt cattctgttt atattttagc atagaatcag tacaaagggc tattttacaa
     9781 aagaaataaa tggtataata ggaaggcact ttgctgaata gaaaggaaga gcagtcaatg
     9841 attggaatca gtgcatgttt aggcggtctg gcctgtcgct atgatggaca gaaaaaagaa
     9901 gtaccagaat tgatggaact agttgaaact ggagaagctg tcatggtctg tccagaagtg
     9961 atcggcggat taccaattcc tagagatccc gctgaaatca ttggtggaaa tggattcgat
    10021 gtgtggaaag atcaagcaaa agtatggacg acaagcggcg aagatgtaac ggaagcgtac
    10081 aaaaatggcg cgatcaaagc ctatcaaaaa ttgcaggaaa aacacattga tctagtcatc
    10141 atgaaggaaa aaagcccttc atgcggaacc cattcgattt atgacggaag tttttccgga
    10201 ataaaaaaaa atggtgccgg agtggctact gcttatttta ttcagcaaaa aatgactgtg
    10261 ctctctgatg aagaatggct gaaaactaga ggtgagcaga atggaaatcg aaaagaccaa
    10321 tcgaatgaac gcgctctttg aattttattc gaccttattg acagaaaaac aaatgaacta
    10381 catggaatta tattatgcag atgatttttc attaggtgag atcgcggaag aatacgaagt
    10441 aagccgacaa gcagtatatg acaatatcaa gcggacaagc aagatcttgg aggattatga
    10501 aaaaaaactc catctttttt ctaattatat tgttcgagaa caggtattgg aaaatatgac
    10561 tgcatatatt acagataagt acccggaaga taaaaaacta cttgaatatg tacagcaaat
    10621 tcaagcaatc gaagaataaa taaaaggaat gaagaaaata tggcatttga aagcttaact
    10681 gaacgtctcc agcaggcgat gggaaaaata agaaaaaaag gaaaagtatc agaagctgac
    10741 gtaaaagaaa tgatgcggga aatccgcctt gccttactag aagccgatgt taacttgcaa
    10801 gtagtcaaag attttactaa gcgcgtacgc gaacgtgcgg taggggcaga agtgctggaa
    10861 agtttatcac ctgcacaaca aatcgtaaaa atcgttgatg aagaattgac gatcacactt
    10921 ggttctgaaa cagcagagtt aaataaatca ccaaaaatac caactgttat catgatggct
    10981 ggtcttcaag gggcaggtaa aacgaccttt actggtaaat tagccaatta tttaaagaaa
    11041 aatgaaaatg ctcgtccgct cctaatcgca ggggacgtat atcgaccagc tgcgatcgac
    11101 caattgaaag tattaggtca acagctagac gttcctgtat ttgatatggg aactgaagtc
    11161 agcccggtag agatcgtccg tcaagggatg gagttagcaa aagaaaagaa aaacgactat
    11221 gtattgatcg atacggcagg acgtctgcat atcgatgaaa cattgatgga tgagttgaaa
    11281 caaatcaaag aattgacgca accaaatgag attttgcttg ttgtcgatgc catgactggt
    11341 caagatgccg tcaacgtagc tgatagcttc aaccagcaat taggtattac aggggtcgtc
    11401 atcactaaac ttgatgggga tactcgaggc ggggcagcac tatcgatccg ctcagtgaca
    11461 ggcgcaccaa tcaaattcat cggttctggt gaaaaattga ctgacttaga agtattccac
    11521 ccagatcgta tggctagccg tatccttggt atgggggata tgctgacatt gattgaaaaa
    11581 gcgcagcaag actacgacga gaaaaaagcg gaagaacttg cacagaaaat gcgggaaaat
    11641 tcattcgatt tcaatgactt tattgaacag cttgatcaag tgatgggtat gggcccactg
    11701 gaagatctaa tcaaaatgat cccaggaatg aatcaagtcc ctggaatcga aaacgtcaag
    11761 gtagatccaa aagatgttga acgcaaaaaa gcgatggttt attctatgac gccagcagaa
    11821 agagcaaatc ctgatctgtt gaacccaagc cgtcgtcgcc gaattgctgc cggttctgga
    11881 aacagtgttg ttgaagtgaa tcgaatgatc aaacaattca aggaatcaag aaaaatgatg
    11941 cagcaaatgt ccaaagggga tatgaacatc ccaggtatgg accaaatgtt tggttcaggc
    12001 gtcaaaggaa aactaggcaa aatggcgatg aatcgaatga tcaagaaaaa taagaagaaa
    12061 aagaaaaaac ggaaataaga tgaaaaaaac agcttcggta cagactgaaa atgtctactg
    12121 ccggagcttt tctatcagca atttttattc tttactaata caattactct aaacgaagag
    12181 gtggcacaga tgagatgtcc gtggagtgaa caaacagaaa gtatgcggca atatcatgat
    12241 actgtctggg gtgttcctga atatgatgac caaaagctgt tccgaaaatt gatgcttgat
    12301 attaatcaag ccggattgag ctggcagacg attttaaata aaagtgaagc attcgatgaa
    12361 gcatatgatc gattcgatat caaaaaagtc gcaaattatg gagaaacaaa aatcagtgaa
    12421 ctaatggaaa acaaaggaat tattcgtaac cgaagaaaaa tcgaagcagc cgtccaaaac
    12481 gccaaagcag tcttgaaaat tcaagaagaa atcggcagtt tttcagagta tctttggtcg
    12541 ttttctaatg gaaaaatcgt tgattcttct tatcattcac aagaagaagt cccaacaaca
    12601 agtcctcttt cagatgaatt agcaaaagat ctaaagaaaa gaggatttaa atttatcgga
    12661 agcacaacaa tctatgcttt tttagaagct gtcgggatca tcaatgatca ccttgacagt
    12721 tgtttccgca aagaagaggt cgtacgtatc ggcagaaagg gcgaataaag catgcgaaaa
    12781 atcatatttt atggtgctat aagtttagat ggctatttgg caacgaaaac ggatgatctt
    12841 caatggcttt ttgacactcc aacaggtaag caaactactt atgaagcttt ttatgaaaca
    12901 atcgatacga ccatcatggg cagaaaaact tatcaggaag caaaaaaata tttggagacc
    12961 gaagcaattt atccagagaa aaagaatttc gttttttcca cccacgcaca attacaattg
    13021 ccagatgctg aggtcgtaaa cgaagatcct gttgcttttc taaaaaatct acaaatgaca
    13081 gaaggaaaag atatctgggt tgtgggtggc ggtcgattga tcaaaccgct attggaacat
    13141 caaatgattg atgaatggta tatccagatt acccctgtat tattagggga cgggattcct
    13201 ttattccaaa aaggaacata tgaagcgcgt tttgaaatgc tagacacgac acgattcggt
    13261 gaatttatcg aattgcatta tgtacgaaag tagaagtaaa taaaataaaa aaggcaacta
    13321 tatgcagaaa tgtcctgtac atagttgcct tttttattac cgttatgctt tttactctgt
    13381 taatttgtta gaaaaatcta gatacgcatc taaaatcgtt tggaagaaac ttaatgttcc
    13441 ttcaacgata ttaccatttt catcaattag attcgcaacg tttccgatat atgcttccgg
    13501 ttgctgcaag gttggcacat tcaaaaagac aagtgattgg cgtagatggt ggtttgcgcc
    13561 aaagccgccg atcccacctg gtgatgcagt aacgactaaa cctggtttat gatcccaaac
    13621 actgtgtcca taaggtcttg agcctacatc taaagcattt ttcaatactg ctggcacaga
    13681 acggttgtat tcaggagtaa cgaaaacgac accgtctagt cccctcactt cctcacgaaa
    13741 acgagtccat tcagcaggag cctgttctgg agtttcgaga tcctcattgt aaaatggcag
    13801 atcatcgatt tttacaaata cactttcgta cccttcagga agcaatttcg caaaagcttc
    13861 tgctactttt ttgttgtaag aatcttttct taaactacca ataaaaaatc caattttttt
    13921 tgtcatacga tttttcctcc ttcaaactat ctataataat cttacaaaag ataagtaact
    13981 ggagcaaata aaaacactta ctgacaaaag ctacatagaa gatagattac ttatttttaa
    14041 caaaaaagaa gtctaaaatc ttctattttc taaaaaaaat cgaatttaat caagctgtaa
    14101 agaaaaaaag ctttacaggg taaaaaaaaa ctgttacact acatcttgtg aataaaacaa
    14161 tggaggtgga aataaataat ggcagttaaa atccgtttaa aacgtatggg ttctaaaaag
    14221 agtccgtttt accgtatcgt cgtagctgat tcacgttctc ctcgtgatgg acgtttcatc
    14281 gaaactgtag gtacttacaa tcctttgaaa gaccctgcag aagtagtttt aaaagaagac
    14341 ttagttcttg actggttatc aaaaggtgca caaccttctg acactgtacg taacatcctt
    14401 tcaaaagaag gcgttatgca aaaacaccac gaagctaaat tctcaaagaa ataaggtgac
    14461 cggatatgaa agatttaagc gacttagtct taacaatcgt tcgtccgcta gtcacttatc
    14521 ctgatcaagt caagttagac gtcgtagagt cgaaagactt ttacgagtac aatctaacag
    14581 tggctcctga agatattggc cgtatcattg gaaaacaagg gcgtgttgct aaagcaatcc
    14641 gcacaatcgt ttacggtgtt cggatcaatg caccgaaaaa agtgcgtttg aatatcatcg
    14701 atgataagga aaagtaaata aa
//
LOCUS       DBBGRF010000067        14625 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000067 DBBGRF010000000
VERSION     DBBGRF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.067"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            4..816
                     /locus_tag="ACIZD4_002467"
     CDS             4..816
                     /locus_tag="ACIZD4_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGC5991345.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="ACIZD4_002468"
     CDS             813..1613
                     /locus_tag="ACIZD4_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGC5991346.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="ACIZD4_002469"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="ACIZD4_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGC5991347.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="ACIZD4_002470"
     CDS             3110..4819
                     /locus_tag="ACIZD4_002470"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGC5991348.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9389
                     /locus_tag="ACIZD4_002471"
     CDS             5031..9389
                     /locus_tag="ACIZD4_002471"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGC5991349.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9534..10007
                     /gene="rimP"
                     /locus_tag="ACIZD4_002472"
     CDS             9534..10007
                     /gene="rimP"
                     /locus_tag="ACIZD4_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGC5991350.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10030..11205
                     /gene="nusA"
                     /locus_tag="ACIZD4_002473"
     CDS             10030..11205
                     /gene="nusA"
                     /locus_tag="ACIZD4_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGC5991351.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11227..11520
                     /locus_tag="ACIZD4_002474"
     CDS             11227..11520
                     /locus_tag="ACIZD4_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGC5991352.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11517..11828
                     /locus_tag="ACIZD4_002475"
     CDS             11517..11828
                     /locus_tag="ACIZD4_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGC5991353.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11841..14147
                     /gene="infB"
                     /locus_tag="ACIZD4_002476"
     CDS             11841..14147
                     /gene="infB"
                     /locus_tag="ACIZD4_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGC5991354.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14174..14521
                     /gene="rbfA"
                     /locus_tag="ACIZD4_002477"
     CDS             14174..14521
                     /gene="rbfA"
                     /locus_tag="ACIZD4_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGC5991355.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4983 a         2598 c         3255 g         3789 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgagtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccacatccag ctaggacgaa
     5701 atattccagc cgatgaacca acgacaccaa tgatcagtat cgttgaagaa gaacgaagag
     5761 tcacacttga ggggtacgta ttcgacaaag aagtcagaga actacgttca aaacgcaaga
     5821 tcttgacttt gaaaatcaca gattatactt catcatttat cgtcaaaaaa ttctcgaacg
     5881 gcgaaaaaga tgaacaagta tttgatgcga tcagtgtcgg tagctggtta aaggtacgag
     5941 gaagtattca agaagatacg tttgtccgtg atttggtcat gaatgcgcaa gatatcatag
     6001 aagtcaaaca tacacctcgc aaagattatg ctcctgaagg ggaaaaacga gtagagcttc
     6061 atgttcatag caatatgagt acgatggatg caacaaacag catctctgat cttgtggcac
     6121 aagcagggaa atggggacac cgagctatcg ccattacaga ccacggtggt gcgcaagcct
     6181 ttccggaagc acatagtgct ggaaaaaaag caggtgtgaa aatcttatac ggcgtggaag
     6241 cgaatgtcgt agatgatggt gtcccaattg cttataatga tgcacatgaa gcattgagtg
     6301 aagccacata tgtcgtattt gacgtggaaa cgacaggatt gtctgcagta tatgacacga
     6361 tcatcgagct agccgcagtc aaaatgtata aaggaaatgt gatcgaaagc tttgatgaat
     6421 ttatcgatcc aggacatcct ttgtcacgaa caacggtaga tctgactggt atcacggatg
     6481 gaatggttcg aggatcaaag tcggaagaag aagtattgcg gatgttcctt gaattttcaa
     6541 aagatacaat tttggtagcc cacaacgcgg cttttgatat ggggttcttg aatactagct
     6601 acgcaaggta tggtattcct gaagcggcca atccagtcat tgatacgttg gaattagcta
     6661 gatatctgta tcctcaattc aaacgtttcg gattaggtgt gttatctaaa aaatttggtg
     6721 tcagcttgga acagcatcac cgagcaatct atgatgctga agcaactggt cacttagcat
     6781 ggatctttgt gaaagaggca atggacaatc ataacatgct ttatcatgat cagctaaatg
     6841 agcatatcgg agaaggagat tcttacaaaa gggctcgacc tttccatgta acgattttag
     6901 caaaaaatca ggcaggactg aaagatttgt tcaaactgat ttcaatgtcg aatgtcgaat
     6961 acttcgaacg cgtcccacga ataccacgct cccaattgaa aaagatgcgt gaaaatctat
     7021 tgatcggctc agcttgtgat aagggagaaa tattcgaagc catgatgcaa aaaggggtag
     7081 aagaggcaag aaaccgagca aaattctacg attatattga agttatgcca aaagcggtct
     7141 atgcgccttt gatcgagcaa gaattggtaa aaaatgaaca tgatttggaa gaaattatcc
     7201 aaaatttggt agaaatcgga aaaagtttgg ataaaatcgt tgttgcaaca ggtaatgtac
     7261 attatctgaa cgaagaagat gccatttacc gaaaaatttt gatcaattct atgggcggag
     7321 cgaatccgtt gaatcgtcat agtttgccgg atgtccattt ccgaacaacc gatgagatgc
     7381 taactgcatt tcacttttta ggggaagaaa cagcgaaaga gatcgtagta gaaaatacga
     7441 ataaaatcgc agatatctgc gaagaagtga ttccagtcaa agatgaactt tatacaccga
     7501 agattccagg ttcagaagat gaaatatcag aattgagtta cacaaaagca aaacaaatgt
     7561 acggagatcc gttacctgag atcattcaaa aacgattaaa aaaagagttg aattctatta
     7621 atggtaatgg cttctcggtt atttatctga tcgcccaaaa actagtgcat aaaagtaatg
     7681 aagatggcta tctagtaggt tcacgtggct ctgttggctc tagctttgtt gcgacgatga
     7741 caggaatcac tgaagttaat ccgttagccc ctcattatta ttgtccagag tgccaatatt
     7801 ccgagttttt tgaagatggt acgtatggtt ctggatttga catgccagaa aaacaatgtc
     7861 caaaatgtgg tgcacgctta aacaaagacg gtcatgatat tccatttgag acatttttag
     7921 gattccatgg agacaaagtg cccgatattg atttgaactt ctcaggtgat tatcaagcag
     7981 aagcccataa ctatacgaaa gtattgtttg gcgaagacta tgtttaccgt gccggaacga
     8041 ttggtacagt cgccgacaaa acagcatatg gctatgtaaa aggatacgaa agggacaata
     8101 atctgcagtt tcgaagtgca gaagtcgaca gattagcaaa aggcgctact ggagtcaaac
     8161 ggacaaccgg ccagcatcca ggggggatca tcgttattcc cgattatatg gatgtctatg
     8221 attttacgcc gatccaatat ccagcagacg atcaaaattc ggaatggaaa acgactcatt
     8281 ttgattttca ctcgattcac gataatgtat tgaaattaga tattctaggg catgatgacc
     8341 caactgttat tcggatgctt caagatttat cagggatcga tccacaaacg atccctacgg
     8401 atgacccgga agtgatgcgg atatttgccg gtcctgaagt acttggagta agtcaggaac
     8461 aaatttattc caaaacaggg acattaggta ttccagaatt cggcactcgt tttgttcgag
     8521 ggatgctaga agaaacgcat cctacaactt ttgcagaact actgcaaatt tccggactat
     8581 ctcatggtac agacgtatgg ttaggaaatg cggaagaatt gattcgacga ggagatgcga
     8641 cactggcgga agtaatcggc tgtcgtgatg atattatggt ttatttgatc catgctggat
     8701 tagatagcgg gatggcattt aaaatcatgg aaactgttcg taaaggacaa tggaacaaga
     8761 tccctgatga attgcgagaa acctatctat cggcgatgaa agaaaataat gtgcccgact
     8821 ggtatatcga ttcttgttca aaaatcaaat atatgtttcc gaaagcccat gctgcagctt
     8881 acgtattgat ggctcttcgt gtcgcttatt tcaaggttta tttccctatt ttgtattact
     8941 gtgcatactt ttctgtacgt gcagacgact ttgatctagt ctccatgtgc aaaggaaaag
     9001 atgctgtgaa acaagcaatg aaagaaatca cggacaaagg attagatgct tccgtaaaag
     9061 aaaagaatca actgacagtg ctggagttag ccaatgaaat gctggaacga ggattcaaat
     9121 ttggaatgat tgatttgtat aaatcggatg ccgttaactt tgttattgaa ggtgatacgt
     9181 tgatcgcacc atttagagct gtcccaagtt tgggaaccaa cgtggcaaaa caaatcgttg
     9241 aagcaagaaa agacggtcca tttttatcca aagaagatct tgccacccgc ggtaaagttt
     9301 caaaaacatt gatcgaatat atgaacgaca atggcgtatt gaaagatcta ccagatgaaa
     9361 atcaattatc gttattcgat atgctataag catctgtttt cctgtctgct tgtaatttta
     9421 agcagagtat ggtatagttc ttataggtaa tgatactaac tgtgagtgag cggatttttc
     9481 gctcactctt tttaatggaa ttacgcactt aattttttaa ggaggcgaaa cttttgagta
     9541 gcgtcgttga aacagtcaca gaaatggtga caccgatttt agatgaacaa aattttgaac
     9601 ttgtcgaagt cgaatttgta aaagaaggaa aaagctggtt cttacgagta tttattgaca
     9661 aagaaggcgg tatcgatatc gaagaatgcg cctttgtcag tgagaaactg agtgaaaaac
     9721 ttgatgcagc agatccagat ccgattcctc aagcttattt cctggaggta tcctccccgg
     9781 gagcagagcg gccattgaaa aaagaaagcg actatgaaaa ggcacttggt gattatgtcc
     9841 atgtctcctt ataccaacca gtagatggcg aaaaacaata tgaaggattt cttcaatcat
     9901 ttgatgctga acagcttaca ttgaaaatac gcataaaaac acgagaaaaa gaattgactt
     9961 ttgaccgaaa aaatattgca aaagctcgct tagctatcca attttaatca cggagaggaa
    10021 tcagaaaaaa tgagtaaaga aatgttaaat gcgttagacg ctttagaagc tgaaaaaggg
    10081 atctcaaaag aaatcgtgat cgatgcttta gaagcagcat tggtttctgc atacaaacgt
    10141 cactatggcc aagcacaaaa cgtcgaagtg gaatttgatc agaaaaaagg aaagatccat
    10201 gtctatgcgg taaaagaagt aacggaagaa gtgatggatt cacagttgga agtctcattg
    10261 aaagatgcac ttttaatcaa tccagcatat gagatcggtg atacgatccg ttttgaagta
    10321 acaccaaaag attttgggcg gatcgctgcg caaacggcta aacaagttat tttacagcgt
    10381 gtacgtgaag cagaaagaac gattatttat aacgaattca gtgcttatga aaaagacatc
    10441 atgcaaggaa tcgtcgaacg ccaggataaa cgttatattt atgtcaatct tggtaaaatt
    10501 gaggcagttc tttctaaaca agatcaaatg ccaaatgaat tttatcaacc acatgatcga
    10561 atcaaagttt atgtttcccg agtagaaaat acgtctaaag gtccgcaagt atttgttagc
    10621 cgcagccatc cagacctatt gcgccgctta tttgagcaag aagtaccaga agtctatgat
    10681 ggaatcgttg aaattgtcag catcgcccgt gaagctggcg atcgttcaaa agtggcagtt
    10741 cgctcaaatg atccaaatat cgatgcagtc ggtacatgtg tcgggccaaa gggacaacga
    10801 gttcaagcaa tcgtcaatga attaaaaggc gaaaacatgg atatcgtcga atggaatgaa
    10861 gatccagctg tattcattgc aaatgcattg aatcctgcac aagtcatgga tgtgatcttc
    10921 gatgagacaa atccaaaggc ctgcacagtt gtcgttccag actaccaatt atcgctagca
    10981 atcggtaaac gcggacaaaa cgcacgttta gctgctaaat tgactaacca taaaatcgat
    11041 atcaaatcag aatctgacat gacggaattt tatgaaaatc aagaacaaca aaaagaaaca
    11101 gaagaactgc atgatgaagc aatcgttcag tcagatttaa cagacgatga atatgaaaca
    11161 attgcattca acaatgaaac ggtcgaagaa aaaccagaag cttaacttta gtaaggaggc
    11221 aaagagatga aacaaaggaa aattccttta cgcaaatccg tggtttcagg tgaaatgaaa
    11281 cctaaaaaag agatggtccg aatcacccgt tcaaaagaag gggaagtatc gatcgatcca
    11341 actggaaaaa tgcctggacg aggagcgtat gtctcacttg agccggaaga agtacaacaa
    11401 gcttgggata aaaaaattct cgatcgagta ctcgaaacaa cattaacaga tgagttttat
    11461 caagaacttc ttgactatgt cactcaccaa aaagcacgta aagagttatt tggaaaatga
    11521 atacagttaa tcggcaaaaa gccatgaatc tcatcggtct agcgatgcgc gcgggaaaac
    11581 taatcacggg tgaagaactg accattgctg aaatccgcaa acaaaaagca aaattggtgt
    11641 ttgtggcaac cgatgcaagc gagaatacaa gaaaaaagat aaaagataag agttcatatt
    11701 atgaagttcc ttgctttgag ctattttctg aagcagaaat cacgcagatg atcggaaaac
    11761 ctcgcaaggt attcggaata atggatgccg gatttgcgaa gaagaccaag gagctaattg
    11821 aaggttagga aggtgattgc atgggcaaca aaagaatcta tgaattagca aaagaactca
    11881 aaaaatctag taaagacgtc gtggaaaaag cacaacaact tggcatcgat gtgaaaaacc
    11941 atatgggtgc gattactagc aatgatgaga agaaattgca acaagcgttc aaaaacccaa
    12001 gcacgaaaca acaagctgca caacaagcaa gcagaaaacc agccaatcaa cagccgaacg
    12061 atcaacgtaa aaaagaaaca acgaacaatc aacaaaaaaa taaaaataac cgcagttatc
    12121 aagatcgcgg tcaagggagc ggtcaagtga atcaaggaaa aaaaccaaca acaaaccaaa
    12181 ataatacggg aaataccagc agccaaaatc gtcaaggaac gagccaaggc ggcaatcaaa
    12241 accgtactaa caataacaac aaaccaaaca ataacaatcg cggcaaattt aataataata
    12301 accgtaatcg ttataataaa aaaggtaaaa aaggcaaaca gcaacaatca actaaaccag
    12361 ctgtaccacc acgcaaattc cgtgaattgc cagatgtatt agagtatact gaaggtatga
    12421 acgtagcaga tattgcgaaa aaaattcatc gtgagccagc agaaatcatt aaaaaattat
    12481 ttatgcttgg tgtcatggtc aatcaaaacc aagcactgga taaagatacg attgaactgt
    12541 tagcgacgga ctatggcatg gaaccacaag aaaaagtcca agttgacatt gctgatatcg
    12601 ataaattctt cgaggcagaa gaagtcgatc cagataaatt agtctcacgt ccgccagtcg
    12661 taacgattat gggacacgta gaccatggga aaacaacttt attggataca ttacgccatt
    12721 cacgtgtaac aagcggcgaa gccggcggaa tcacacagca tatcggtgcc taccagatcg
    12781 atattgatgg taaaccaatc actttcttgg atacaccagg acatgcggcc tttacaagta
    12841 tgcgtgcacg tggagcaagt atcacagata tcacgatctt agttgttgct gcagatgatg
    12901 gcgtcatgcc acaaacagtt gaagcaatca accatgccaa agctgcaggc gttccaatca
    12961 tcgtcgctgt aaataaaatt gataaaccag gtgcaaaccc tcaacatgtt atgcaagaat
    13021 taagtgagta tgagttaatt cctgaagcat ggggtggaga aacgatcttt gttgagatct
    13081 cagcgaaatt cggccaaaac atcgaagaat tgctggaaat gatcctgtta gtcgcagaag
    13141 tagaagattt aaaagcagat ccaacacaac gcgcaatcgg aacagtgatc gaagcacgtc
    13201 ttgataaagg taaaggtcct gtgtcaacct tacttgtcca agaaggaaca cttcatgttg
    13261 gtgacccaat cgttgtcggt aatacttacg gacgtgtccg tgtaatgaca aacgatcttg
    13321 gccgtcgcga taaagaagca ggacctgcaa cgccagtaga aatcactggc ttgaatgatg
    13381 tacctcaagc aggtgaccgt ttcgtagtct tcgaagacga aaagacagca cgtgcagcgg
    13441 gtgaagaacg cgcgaaacgt gcattattag aaaaccgtgc tgccacaagc cgtgtgactt
    13501 tggataactt atttgaaagc ctgaaagaag gcgaattgaa agaagttaac gtaatcatca
    13561 aagcagatgt acaaggttca gcagaagcac tggctgcatc attgaagaag attgatgtgg
    13621 aaggtgtccg tgtaaaaatc gtccattcag ctgtcggagc aatcaatgaa agtgatgtaa
    13681 ccttagcagc agccagcaac gctattatca tcggtttcaa cgttcgtcct acaccgcagg
    13741 caaaagtgca agctgatact gaagaagtcg atattcgtct tcaccgtatc atctataaag
    13801 ccatcgaaga aatcgaaact gcgatgaaag ggatgctaga ccctgaattt gaagaaaaaa
    13861 tcaccggtca aatgatcgtt cgtgaaacct tcaaagtttc taaagttggt acgattgcag
    13921 gtgcctatgt aacagaagga tatattcgta gagatagcgg tgtccgtgta atccgtgacg
    13981 gaatcgtaat ctatgaaggc caacttgcaa gtctgaaacg attcaaagat gacgtgaaag
    14041 aagtcaaaat gggttatgaa tgtggtgcaa tgattgaaaa attcaatgac atcaaagtag
    14101 atgacgtaat tgaaggattt atcatggaag aagtcaaaaa tgactaaaaa ctgataaaag
    14161 gaggccaatc attatggcta actaccgtga ccgccgagtc ggtcaagaaa tcttaaaaga
    14221 agtcaatgat attttgcgca aaaaggtccg tgaccctcgt gtggagaacg taacgatcac
    14281 agatgtgaaa gttacggggg acttacagca agcaacgatc tattacagca ttttatctga
    14341 cttagcatca gataagaaaa cagcacaaga tggattgaat aaagcatcag gattgattcg
    14401 tcgagagtta gggcacaatc taagtattta taagacacct gaattgttct ttgaacttga
    14461 tgaatcagtt gtctatggca accatatcga tgaattgctt cgcgacttga acaaagacta
    14521 atcaaaaact cccgcaaatc ctgtgaaatc aggctctttg tcaataagga ctgatgagtt
    14581 gtgcaaaatc aaatctgagt cagaatgaac cacattctgg ctcag
//
LOCUS       DBBGRF010000068        13967 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000068 DBBGRF010000000
VERSION     DBBGRF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.068"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            135..455
                     /locus_tag="ACIZD4_002478"
     CDS             135..455
                     /locus_tag="ACIZD4_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991356.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            907..1107
                     /locus_tag="ACIZD4_002479"
     CDS             907..1107
                     /locus_tag="ACIZD4_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HGC5991357.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1254..4043
                     /locus_tag="ACIZD4_002480"
     CDS             1254..4043
                     /locus_tag="ACIZD4_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HGC5991358.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4090..4617
                     /locus_tag="ACIZD4_002481"
     CDS             4090..4617
                     /locus_tag="ACIZD4_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGC5991359.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4638..5828
                     /locus_tag="ACIZD4_002482"
     CDS             4638..5828
                     /locus_tag="ACIZD4_002482"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGC5991360.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5868..7166
                     /gene="asnS"
                     /locus_tag="ACIZD4_002483"
     CDS             5868..7166
                     /gene="asnS"
                     /locus_tag="ACIZD4_002483"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGC5991361.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKITFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            7961..8635
                     /locus_tag="ACIZD4_002484"
     CDS             7961..8635
                     /locus_tag="ACIZD4_002484"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGC5991362.1"
                     /translation="MKKRILFIGDSITDAGRYRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIVAVDFFSGDKNE
                     RKKSEK"
     gene            8632..8973
                     /locus_tag="ACIZD4_002485"
     CDS             8632..8973
                     /locus_tag="ACIZD4_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991363.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            9003..9362
                     /locus_tag="ACIZD4_002486"
     CDS             9003..9362
                     /locus_tag="ACIZD4_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HGC5991364.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            9622..9744
                     /locus_tag="ACIZD4_002487"
     CDS             9622..9744
                     /locus_tag="ACIZD4_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991365.1"
                     /translation="MNLDKLPATGFKLSCYPVKIKKASAGWIRAVAMIEEKKKE"
     gene            9886..11970
                     /locus_tag="ACIZD4_002488"
     CDS             9886..11970
                     /locus_tag="ACIZD4_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC5991366.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKKRNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     RAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDPTGIDPKKFMQYVASAEQFSTHPIAQSVLEGYAGPLL
                     PTANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGY
                     LVIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDK
                     VQRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQP
                     SKIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVL
                     NAMRSLHVKNKR"
     gene            12281..13747
                     /locus_tag="ACIZD4_002489"
     CDS             12281..13747
                     /locus_tag="ACIZD4_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGC5991367.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4630 a         2430 c         2973 g         3934 t
ORIGIN      
        1 gaggttgtga cgtggtcacg acctcttttt gacgattatg atacaaaaaa catcatttat
       61 gaacaaaatg tgaataacgg gcgttcttga gatatgattt taattgggaa aaacttatcg
      121 ataaggaggt ctttatgaaa aaaagactgt tatggtgttt gctgtttcta tccctaagtt
      181 taacaagtca gccagttttt gctgaagaaa cacagcggtc tcctattaca ggcacacgtc
      241 tgtacaaaaa tgtttatgta cagacaacag atcttgattc tgcgattcct gaaacagaag
      301 aacggtcttt gcagccaaga tttggttact tttggtactg tccgacctgt gattatgaaa
      361 gttgctggca tttcttacat tctacagctg cagcttttgc ttttactcat actcagaaat
      421 atgatggaca tcatcctgtt atttatgagg tatagatatg agcaaaaaag aaaaactaat
      481 ctcgttgatc gtattggttt gccttgttct tctggtaact gtcataggct atcagaaata
      541 ccatgagaac atcagaccta ctaaagaatc ttccccagcc tcgaccgttg aaacagaacc
      601 gataagtagt cagaaagaat aattttttta gtttaaagaa gaacatcaga gcaaaaaaac
      661 accaactgaa caatatgtcg tttattttaa aaaaagttcg gtttttcact ttatgtaatc
      721 gctgagaaaa ctttttttaa taaaaaaagt cgaaaaactc tagctttttt gtaaacggta
      781 tgatatacta taggagtagt ttttgttcgg taatctgtgg tagcttgttt caaataaaca
      841 tcttccagat atacaccatt caagtaattg caaaatatgt gttgatacac aaggaggatt
      901 tttattatgg aaacaggtac agtaaaatgg tttaactcag aaaaaggatt tggattcatc
      961 actgcagaaa acggaaacga tgtattcgtt catttctcag ctatccaagg cgacggattc
     1021 aaaactttag aagaaggcca agcagtaact ttcgatgttg aagaaggcca acgcggacct
     1081 caagcaacaa acgttactaa agcttaatta acctatacta aaaaataaac gcccagacat
     1141 ttgcgtgtct gggcgttttt gtctattttc tttaaaaagc gatgagagta tttttctgca
     1201 ctttgtagta taatttcaaa agaacattag aggcaggaga agaggaagat attttgaaac
     1261 caagaactta tgcagtcgtt gatatcgaaa cgactgggac gaatccaaaa gaagatcgga
     1321 tcatccaatt tggctgcgtc atgattgaat caggtcggat cacttcacgt ttttcgatcg
     1381 atattcatcc agggcggaag atttcaaaac aaatccagca tttaacaggg atcacgaatc
     1441 aacgcgtcca aaaagcgcct tatttcgaag atgtcgccca aacgatttac aatcttttgg
     1501 cagacaccat atttgtcgcg cataatattt attttgatta taattttttg aaccatgaac
     1561 tcatgcgatg cggacttcct agtttgaaga taccaggcat cgatacagta gaacttgcac
     1621 aaattttctt gccgacggaa ccaagctttc gcttagctga tttgtcagaa agccttggat
     1681 ttattcatga gaatcctcat caggcagata gtgatgccga agtgacgggt caacttcttt
     1741 tgctgatcga agaacggatg agaaaattgc caatcatcac gttagagcag attgcgcgat
     1801 taagtagaca cacaggtatg gatacgagtc gtttcattta tcatgtgatt gaagaaatga
     1861 aagaaaaacc agagccactt gatccctcat tagaaatcgt cgatgggcta gctttgcaga
     1921 aaaaagaagt ggaactattc acatccgtcc attatggcga gcggacatat ccaagaaaaa
     1981 aacaagcaaa agaaaaaatg tttggtaaaa cactgatgta tcgaaaagaa cagaacagac
     2041 tgatgaatgc ggtctacgac catttcacaa aagatgaatc aaaagatttg atgatcgaag
     2101 cagctacagg aatgggtaaa acaatcggtt atctgctgcc attgagttat ttggctacac
     2161 ctgaaaaacc cgctgtcatc agtaccgttt cgctagtttt gcagcagcag atcatagaaa
     2221 aagacattcc attgctgaat caattgctag atcagcccat acaacctgta attatcaaaa
     2281 gctatcgcca ctatattgat ttacagcgtt ttaaaggcac acttgtggaa ccgccagaac
     2341 aaaaacaata tgctttgtat caaatggcgg tcttagtttg gctgacgcaa acgaagaccg
     2401 gtgatttgga tgaattacat ttaacaaatt tgaaccattc attctttgca gatatcgcgc
     2461 acagaggtat tggattttta gcaagaaatc agtcatttta cgaacaagac tttgttcgtt
     2521 tcttgcaaaa gaaaatcagg caaagtaatt ttttgattgt caatcatgcg tttttaatac
     2581 aagaaacaca gcgaaaagaa ccattgcttc cagctagtcc atttttgttg atcgatgaag
     2641 tacatcattt gccggaaatc gctgaaaaag taaatgacaa acgattaagt attaactatt
     2701 tccataaaca aatccagcaa ttagaagaac caaatcagct gtttgaccga atacaaagct
     2761 atttaccgaa agaacatgaa gccttacgct ggttatcgat ttatcgagaa gaactttctg
     2821 cgctatgcga agcacagatt tgtatggcag aaggattaat gagtttagtg agcggcaagc
     2881 aacctaacgg acagtatcca gaagaagtca tgatgacaaa agagatgttg gatcagctgc
     2941 cactggaatc tgggacagcc attgatcacc tgcagctttt ttatcaggag atccagcagc
     3001 tacagtcaca aatgcgtctg acttttgaga ttatccaaga aagctggaca aaccagatgc
     3061 ggatcgattt agcaagttta tatagcttat ttgatcaatt agacaagcag tacttgctga
     3121 tggatcaatg gctggaagac tggcgagatc atttgatcca ttggttcgtt cctgggaaca
     3181 cagcgcagca gatgattttt catctccatg attttcaagc ggctatgttg ccgtcgactg
     3241 tttggtatcc tcgatatgat cgtattcttt atattggagg aacgctgaag atcggcccta
     3301 atcgacacta tctctctaag cggcttggca ttgaagcagc acctcttaaa gtgattgcct
     3361 ctccttatga ttatgagaaa caggcaagga tctatgtgcc aaaagaggca cctgccgtcc
     3421 atcaagtcag caatcaagca tatatcgatt atttagagac agcacttaca ggtctgatcg
     3481 aacaagaaga tcggccaata cttgtgttat tcacttctca tgatgttttg cagaaggtct
     3541 atcagaaaat gcatctgtct atgctagaaa aaggacgaga aatactagct caagggtttg
     3601 gcggaagccg ggagaagctt ttgaaacgct tcattttgtc agaaaaaagc gtattgtttg
     3661 gcgctgacag cttttgggaa ggtgtagatt tgcctgggga tgctttgcag atcgttgtag
     3721 tcacacgttt acccttcgat aatccgcttc gcccgatggt caaagctagg aacgcttatt
     3781 tagaatcaga ggggatcaat cctttttacc aggaatccgt acctaaagca gctttgaagt
     3841 tacgccaagc attaggtcgc ttgataagga cggagacaga tcgtggcgta ttgcttattt
     3901 tggatcgaag actagtcact gcaaaatatg gtgcacggat catccatgca ttaccgaaaa
     3961 aagtaccgat caaagagcta gctatggagg aaatctatca ggacatccat gaattcttaa
     4021 agaaaaatga agaaggaagt tagaggagct gtcttttttc ataattaaaa tctgctataa
     4081 tgaaaaggaa tgaagataaa ggagcgacga cccttgaaga aaaaacagac aaaggaaaaa
     4141 acgattaatc gcgtgttact tggcttgatc gtatttttat tagcggtcat cgtgatcagc
     4201 tcgatttttt acttgcgttc cagtcgtccg gcggtgcagg cgaagaaaga agcagtagaa
     4261 atcgcaaaga aatatgcaaa tcttgaggaa gccgatcatt tttattggtt tactcgaaag
     4321 aagacatact tttcactgac aggtacaaat gataaaggaa aagaaatcgc cgttatcatt
     4381 cctaaatctg gtgaaaaagt aaaagtattg gatcaaacaa agggactgac tgaaaacgaa
     4441 gcaaaacaga caattgctgc ggcccatcct gaaatccaaa tcgaaaaagc tgctttaggg
     4501 atgtatgatg atcagcctgt gtgggaagta gtaggaaaag aaacaaatgg gaaactgaat
     4561 tattacctga ttggctttga atctggagat gaagtcaaga caatcaaggg aatttaaaag
     4621 gtaaaggaat gaatgggatg gagttatcaa aaagaacaaa acgattagaa ccgtctgtca
     4681 ctttggcagc tgcggcaaag gccaaggcat taaaagcaaa aggcagagat gtgctgagtt
     4741 tgactgtggg agaaccggat tttgcgacac cagaaaacat ccaagaagca gcaatcgaag
     4801 caatccgcaa tgggaaagct agctattata caccaacagc aggaatccca gagcttcgac
     4861 aggcaatcgt tgattatctg aagaaaaact atggacttgt ctatgaacct tcacaaacag
     4921 tcgtaacaga cggagcgaaa tttgctttgt ataccctttt ccaaacgatc cttgacccgc
     4981 aagatgaagt catcattcct gtgccttact gggtcagtta cggtgagcaa gtaaaactgg
     5041 cagaaggact tcctgtcttt gtgaaagggg aagaatccaa tagctggaaa gttactgttg
     5101 aacagctaga acaagcacgt tcagaaaaaa caaaagccgt aatcatcaat tctccatcga
     5161 atccgactgg aatgatttat agcaagaatg aacttcaggc aatcggtgaa tgggcagtaa
     5221 aaaatgatat tttgatagtt gctgatgata tttatggtcg tttagtttat aatggcaatg
     5281 agtttactcc aattgcaacg atttcagaag caatcaaaaa tcagaccatc atcatcaatg
     5341 gcgtgtctaa aacatatgcg atgacaggct ggcgcattgg ttatgcggtg gggaattctg
     5401 agatcatcaa tggaatgatt gctgttgctt cccagtcaac cagtaatccg acagcagtca
     5461 gtcaatatgc agctgttgaa gcattgaaag gtgagcaaga tacagtagaa gaaatgcgga
     5521 acgcctttga agaacgcctg aatacgttat atccgcttgt ggcagaactg ccaggtgttt
     5581 ctcttgaaaa gccgcaagga gctttctatc tttttcctaa tgtaaaagaa acgctacgca
     5641 tgtgtaaata tgaaaatgtc acacaatggg tagaagatct tttagaagaa acaggggtag
     5701 cgcttgtgac tggcgaaggc tttggggcac cagaaaatgt ccgcatgagt tatgctactg
     5761 atcgcgctac gttagaagaa gcggtacgca gaatcaagca atttattgag agtaaaagtc
     5821 aaaattaatc ctgaagaaat tcaaggaata taaaaggaga gtcatacgtg gaacaaattc
     5881 aaatcatcga ttcgaaaaac catgtgggag aaacagtaac aatcggcgct tgggtcgcaa
     5941 ataagcgatc aagcggaaaa atcacatttt tacaattaag agacggaaca gcctttttcc
     6001 aaggtgtagt tgtaaaaagc gaagtgtcgg aagaagtttt ccaaacagct aaaaatctac
     6061 accaagaaac atccgtgtta gtaactggag aaatccgtga agacagtcgt tcaaaatttg
     6121 gttatgaaat cggaattaca aatgtggaag tggtaagcga gagccacgat tatccgatca
     6181 caccaaaaga acacggaaca gacttcttga tggatcatcg tcatttatgg ctgcgttctt
     6241 caagacaaca tgcgattatg cagatcagaa atgaaatcat tcgtgcaacg tatgaattct
     6301 ttaatcaaca tcattttgtc aaaattgatc cgccgatctt gactggttct gcaccagaag
     6361 gcactacgga tctattcgaa acaaattact ttgatcaaaa agcttattta tctcaaagtg
     6421 gccaattata catggaagct gctgctatgg ctttcggaaa agtcttttca ttcggtccga
     6481 ctttccgtgc tgaaaaatca aaaacacgac gtcatttgat cgaattctgg atgatcgaac
     6541 cagaaatggc tttcactcat caagaagaaa gtttagaagt acaggaacaa tatgtagcat
     6601 tcttagtaca aaatgtttta gatcattgcg aatacgcatt agatgtacta ggacgagaca
     6661 aagaagtctt aaaaacttat acaaaattgc cattccctcg tattacttac gatgatgcaa
     6721 tcgaattact gaagaaaaat ggatttgatg acatcgaatg gggcgaagac tttggttcac
     6781 ctcatgaaac gttcattgcg aattcattcg aacagcctgt ctttatccta aactatccaa
     6841 aagccatcaa gccattctac atgaaaccac atccaacaag agaagacgtg gtaatttgtg
     6901 cagatatgat cgcaccagaa ggttacggtg aaattattgg cggaagcgaa cgggcaacgg
     6961 actatgattt cttgctagaa caaatccgta atcacggttt ggatgaaaaa gaatattcat
     7021 ggtatcttga tctacgtaaa tacggttctg ttccgcactc tggttttggt ctaggtcttg
     7081 aacgaacagt cacttggatt gctggtatcg accatgtacg tgaagctatt ccattcccac
     7141 gtttgttgaa ccgaatttat ccataagagg ttgtgcgcct gccgttcagc tccgagtcac
     7201 aaggagtaat ttcaaaaaac agtttttcat gtttgatgac tattgtgact tgtggccgga
     7261 gagcaacgtt tatttaaaaa aaagaactgc gaactctcgc agttcttttt tttaaatacg
     7321 ggataatgga agtttccagc agacaagaga agaaagcaaa agaaattgct atttgattca
     7381 caaggttcta taacgaaatc gcaatcaatc aaacatttac aaagaaggta attcaaatgg
     7441 aaatctgatt tgatgatgct tctgctgttg aaataaagca gcatctagca cctgaaaaca
     7501 aactaatagt aacattcgaa gatggagtag gtccgtattt tcagcatgca ataatccata
     7561 tgtaagttca attcaccctt gaaatcatcg gaccagataa agttatgacc aatctatccc
     7621 aagcaatcta gaagagatat tagtaaaggg acatttacta gaagtcttag atgagcctat
     7681 aaatatatgt ttcgatggcg tcatcagtgg tctgattgac ggaagcttgg gtgtgatcga
     7741 tctctctgga ccaaacaacg aaggaatcaa ggggaatccg gcacgttaag aaaaaaatag
     7801 cataaaaaac tagacacttg atgagcgttc attcaattgt ttgaaggaac taggctggtg
     7861 tcatttttta tacatatatt ttctctttcg tcttgatagg gcttatggga taatataagg
     7921 aagaaaatca tcgttttatt caaaaaggag tttttgacaa atgaaaaaac gtatattatt
     7981 tatcggtgat agcattacag acgcaggaag ataccgagca gaagcaactg atctaggtaa
     8041 aggttatcca cttttgattg ccggaaaact aatctcccaa tatccaacga tggaatttga
     8101 atgcatgaac cgtgggatag gaggagacaa aattgcagat ctgcaagtac gctggcaaga
     8161 agattgttta gctttacaac ctgactatgt atcgattttg atcggaatca atgatacctg
     8221 gcataatact agcgatcagg ctatattcgg aactgagaaa tctgctcagc aatttgaatc
     8281 cgtttatcga aaattactaa atgaacttca aacagcggaa atctgcaaca tcatcttgat
     8341 ggagccgttt gtacttccta taaccgacga ccgtcatggc tggcgtaaag acttagaccc
     8401 taaaatccaa attgttcgta aacttgctaa ggaatatggc gcattgctgg ttcctttaga
     8461 tggtatattc aatgctttag ggattgctta tggtttttcg aaatatacaa gagaagatgg
     8521 ggtccaccca acgattggcg gacatgagat cattgcacaa agctggatag atgcaattgt
     8581 cgcagtcgat ttttttagtg gagataaaaa tgagcgaaag aaaagtgaaa aatgatggaa
     8641 ataaggtggg cagtaaaaga agatttacct caaatcaatc agctgattac tgatcatcca
     8701 gaatcattcg taaaagcaaa aacggcagct gacctaaatg ataagaataa actattgctc
     8761 gttgctgtaa caaaagaaaa acggattatc ggatttgcgc aagcggacgt gcaacagtca
     8821 gaagaacgat tggatcagcg accatcagga aaactaatcc aacacacatt agtaacaaaa
     8881 gaaaatacgg aagaaatcca aaaaaaattt gcagaatact tgatgctgga agctaaaaaa
     8941 agaagaataa aatcaatttt tgcccagttt taatcaaaaa cagtaataga aggagaaata
     9001 caatgagttg tttaggaaat gtcatctggt ttatattcgg cggactaatc ggtggtctta
     9061 gctggttagc agcggggata ctttggtgta tcacgatcat aggtatccca atcggtatgc
     9121 aatgttttaa gatcgcctcc ctttcttttg cgccttttgg caaagaagta atttatcacc
     9181 agtctggcat gtcattgatc gttaatatca tctggctgat cgtttcaggc ctaccaattg
     9241 ctctcgcaca tgtcgtcagc ggcatccttc tatgtatcac gatcataggg ataccttttg
     9301 ccaagcaatc tttcaaactt gctcgattgg cgttgatgcc attcggtgca gaaattgtat
     9361 aaaagagaat aataaaggtt agataaagca tagagccagg tgggatacat gtatttcacc
     9421 tgactctatg cgttttcctg tataagttct tctatgtgac ttttacgtct tttatttata
     9481 tggggttact gtttatggaa agttgaaata attttcatta aagaactctt tctatatttt
     9541 tgaaagcgta gtggagcttc gtatatctgg gaaggacatt ttgcagggat tgaaaaaaga
     9601 tattgtccta tcgaaaaatt aatgaattta gacaaattgc cagcaacagg cttcaaactt
     9661 agttgctatc ctgtcaagat caagaaggca agtgcgggtt ggataagagc agtggcaatg
     9721 atcgaagaga aaaagaaaga ataagccaaa acatctgtat ggaagaaatt ttccgatgca
     9781 gatgtttttc attttttctt tcggatacct tgacatatga ataaccattc atttataatt
     9841 agttatgaag agatattcat atgttgaggc gaggaggtca ttaaaatgaa aagttacaga
     9901 ttagaaggtt tagattgtgc gaactgtgca atgaaaatcg aaaaaggagt tcagaaaatc
     9961 aatggagtca aggaagcaac ggtaaacttc acttctggaa aactaacgat tgacgcagag
    10021 gaagatcatt tggctacgat tgaacaagaa acaaaaaaag tagtgaagga attagaacca
    10081 gatgtcaaag taacagaaat agataaggaa aaagtatctg aacatggaaa tgaaaaaaag
    10141 agaaatacgc tgttccggat tttattttcc cttgcaggta tcgctttatt gctattattt
    10201 gattttaatg aaccaattcg cttgataggg tatttattga tttatctgct gataggatat
    10261 gatgtagtga agaaggcagt gatgaatatc gtcaaaggaa aaatctttga tgagaatttt
    10321 cttatgtctg ttgctacgat tggcgctatg ttgatcggtg aatatccaga agccgtagca
    10381 gtgatgctat tttatcaaat cggcgagtat ttccaaggat tggcagtcag tcattcaaga
    10441 aaatcgattc gcgaattgat ggcgatccgt ccagaaacag ctcacgtgca gacggcggaa
    10501 ggattgatga ccgtgaaccc tgaagacgtg ctgatcggtc agtttgtact tgtgaagcct
    10561 ggtgaacgtg taccgttaga tggaacgatc atcgaaggag aatcattagt cgatacgtca
    10621 gcacttacag gagaatcagt ccctaaatct gtatatgttg gtgaaacagt attaagcgga
    10681 tttatcaata aaaataaacc atttttagtt caagtagaaa aatcttatga aaattctact
    10741 atcagcaaat tattagaatt agtagaaaat gccagcagta aaaaagcacc agctgaaaat
    10801 ttcattacta aattcgcgcg ctattacaca ccagtcgttg taggattggc cgttttatta
    10861 gctgttttac ctccacttgt tgtttctaga gcggcgtttt ctgaatggat ctatcgagca
    10921 ttgacatttt tagtgatctc atgtccatgt gcattagtga tttccgtgcc acttagtttc
    10981 tttggcggta tcggaggagc aagtaaaatc ggtgtattag taaaaggttc aaattacttg
    11041 gagttgcttg cacaaactga gacagtggta ttcgataaaa ctggcacatt aacgaaaggt
    11101 gacttttcga tccagacgat cgatccaaca ggaattgatc caaagaaatt tatgcaatat
    11161 gttgcaagtg cagaacagtt ttctacacat ccgattgctc aatctgtttt agaaggctac
    11221 gcaggtccgc ttttaccaac agctaatatc caggaatttg caggtgaagg gatcttagct
    11281 gaagttgatg gcaaacaagt attagtaggt aatcacaaat tgatggaaag atttgaaatc
    11341 tcttttcctt caagtcaaga aatcggtaca ttgctttatc tagcgatcga tcaaagttac
    11401 agtggttatc ttgttattgc agataccttg aaagaagatg ccgtagacgc attggttcaa
    11461 ttaaaacagg ctggtgtgaa aaacacagtc atgttgacgg gcgactcgaa aaaaattgct
    11521 gatcatatcg ggaagcaagt aggcgtggac aagatatata gcgaattgct tccagaagat
    11581 aaagtgcagc ggttagagga aatcttacaa agtaacaata aaaagaccgc atttgtcgga
    11641 gatggaatca acgatgcacc ggtgctagca agagcagatg taggaatcgc aatgggtgga
    11701 ttgggaagcg atgctgcaat tgaagcagca gatgtagtca tcatgaatga tcaaccatcg
    11761 aagattgcag aagcaatcca tttagcaaag aaaacattga aaatcgtcaa acagaacatt
    11821 gtctttgcta ttgggataaa aattttggta ctttccttag gtgcttttgg ttttgcatca
    11881 atgggagatg cagtatttgc agatgttggg gtgacagtat tagctgtttt gaatgccatg
    11941 cgaagcttgc atgtaaaaaa taaacgttga tcaatgaaga ggacgaatga acgtcctctt
    12001 ttttttatat ccttttctta atgaaaaatg taaagaaaat agataggatt ataaaataac
    12061 taatgttttt aattttgcag aaaattcaaa atagcttgaa attcaataag gtcaatgaaa
    12121 taaaagaaaa taacttattt ttttgatgga aaaaatatga aaaaacgatg tgtattaaat
    12181 aaaagaatac acacataaaa taacactgtc ttgtaagttt gttaaaaatt gaatatgatt
    12241 acatctggat aacaaatttt tatcataaag gagagaacga atgaacaaca aacaattacg
    12301 ctggtttact gttgcgttaa ttgcatttaa catggtttgg ggcatgggga atgtagttaa
    12361 taactatgct cagcaaggag tatcagttgt cacctcttgg ctattgattt tggccattta
    12421 ttttattcca tacgcattga tcgttggaca attaggatca gccttcaagg atagtaaagg
    12481 aggcgtcagt tcatgggtcg aaaatacgac atctaataaa cgactggcat actatgccgc
    12541 ttggacttac tgggtcgtcc atattcctta tttggcacaa aagcctcaag caattctgat
    12601 tgctggtggt tgggcagtcc aaggaaatgg aaatatcgta aatacgatgt cagtacaaat
    12661 ggtagcagtt atttcactta ttatatttct tgccttttta tatttatcaa caaaaggact
    12721 ttctactttg aaagtgattg gcggactggc cggaacagcg atgttcgtca tgtcgatctt
    12781 atttattctt ttagctgtaa cggcaccgtt catcaatcca acgatggaat ttgccacacc
    12841 acatatgaat caagtgaaaa catatattcc aacatttgat ttcagttatt tcacaaccgt
    12901 ttcgatgcta gtatttgcag ttggaggggc ggaaaaaata tccccttatg tcaactctac
    12961 aagaaatcct gcaaaggaat ttcctaaagg gatgatcttc ttagcagcaa tggtagggat
    13021 ttgtgctgta ttaggctcag tcgcaatggg tatgctgttt gctagcgata atatccctaa
    13081 agacttgatg gcaaatgggg catacagtgc ttttcaaatt ttaggtaatt actatggtat
    13141 cggtaactca ttgatgatca tttacgcatt gacaaacatg attggacaaa tctccgcatt
    13201 agccttttca attgatgcac cactaaaaat cttgttagca gatgcggatc cagaatttgt
    13261 accaaactgg ctacgtaaac gtaatcgtaa aggtacattg gtgaatggtt atcttctgac
    13321 aggtatacta gtaggaatca ttattttgtt gccgatcttt ggtatcaaag atatgaatga
    13381 attagtaaaa tggttgacga acttgaactc agttgtcatg ccaatgcgtt acctatgggt
    13441 gttcttggca tatatgatgt tgaataaagc ttataagaaa ttcaattctg aatataaatt
    13501 tgttaaaaat ccaaaaatcg gttttatctt tggtgcttgg tgctttgcct tcactgcgtt
    13561 tgcatgtatc ctaggaatgg tgccaaaagt agattatact gctgatccta aagcatggtg
    13621 gttccaatta ttcacgaata tcatcacacc aattgtcttg atcttattag gtatgatctt
    13681 gccagcaatt gctcgtcgag acaaaaacaa agaaattact gaaccagaaa cagtggttca
    13741 gccttaaaat agaaatactt gttacaagag gttgtgacag aagctacttc tggaacaccg
    13801 tgaatcagag gttgtgaaaa agctgtcctg catcaagtaa taagaacagc caaacaaaaa
    13861 tagctcctca tattttgccg ttttttgagc taatgctgaa ggtcagctga ttgaacacca
    13921 tttattcgaa acaagggact ttgacacgac ttttgtcaca gtccctt
//
LOCUS       DBBGRF010000069        13917 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000069 DBBGRF010000000
VERSION     DBBGRF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.069"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            131..505
                     /locus_tag="ACIZD4_002490"
     CDS             131..505
                     /locus_tag="ACIZD4_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HGC5991368.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACIZD4_002491"
     CDS             complement(619..1248)
                     /locus_tag="ACIZD4_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HGC5991369.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACIZD4_002492"
     tRNA            complement(1382..1454)
                     /locus_tag="ACIZD4_002492"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="ACIZD4_002493"
     tRNA            1668..1741
                     /locus_tag="ACIZD4_002493"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="ACIZD4_002494"
     CDS             complement(1879..2043)
                     /locus_tag="ACIZD4_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991370.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="ACIZD4_002495"
     CDS             2338..3666
                     /locus_tag="ACIZD4_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HGC5991371.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="ACIZD4_002496"
     CDS             3868..4701
                     /locus_tag="ACIZD4_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HGC5991372.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="ACIZD4_002497"
     CDS             4717..5454
                     /locus_tag="ACIZD4_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGC5991373.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="ACIZD4_002498"
     CDS             complement(5609..6577)
                     /locus_tag="ACIZD4_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGC5991374.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="ACIZD4_002499"
     CDS             6809..7642
                     /locus_tag="ACIZD4_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HGC5991375.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="ACIZD4_002500"
     CDS             7676..8515
                     /locus_tag="ACIZD4_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC5991376.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="ACIZD4_002501"
     CDS             8541..9101
                     /locus_tag="ACIZD4_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGC5991377.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="ACIZD4_002502"
     CDS             9300..11021
                     /locus_tag="ACIZD4_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGC5991378.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="ACIZD4_002503"
     CDS             11186..12328
                     /locus_tag="ACIZD4_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGC5991379.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="ACIZD4_002504"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="ACIZD4_002504"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGC5991380.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4751 a         2298 c         2833 g         4035 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttg
//
LOCUS       DBBGRF010000070        13796 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000070 DBBGRF010000000
VERSION     DBBGRF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.070"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(1..324)
                     /locus_tag="ACIZD4_002505"
                     /pseudo
     CDS             complement(1..324)
                     /locus_tag="ACIZD4_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(369..1495)
                     /locus_tag="ACIZD4_002506"
     CDS             complement(join(369..1267,1267..1495))
                     /locus_tag="ACIZD4_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC5991381.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(1899..2681)
                     /locus_tag="ACIZD4_002507"
     CDS             complement(1899..2681)
                     /locus_tag="ACIZD4_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991382.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(2746..3582)
                     /locus_tag="ACIZD4_002508"
     CDS             complement(2746..3582)
                     /locus_tag="ACIZD4_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC5991383.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(3600..5009)
                     /locus_tag="ACIZD4_002509"
     CDS             complement(3600..5009)
                     /locus_tag="ACIZD4_002509"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC5991384.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(5023..6846)
                     /locus_tag="ACIZD4_002510"
     CDS             complement(5023..6846)
                     /locus_tag="ACIZD4_002510"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGC5991385.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(7689..8015)
                     /locus_tag="ACIZD4_002511"
     CDS             complement(7689..8015)
                     /locus_tag="ACIZD4_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991386.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(8061..8423)
                     /locus_tag="ACIZD4_002512"
     CDS             complement(8061..8423)
                     /locus_tag="ACIZD4_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HGC5991387.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(8460..8674)
                     /locus_tag="ACIZD4_002513"
                     /pseudo
     CDS             complement(8460..8674)
                     /locus_tag="ACIZD4_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            8802..9137
                     /locus_tag="ACIZD4_002514"
     CDS             8802..9137
                     /locus_tag="ACIZD4_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5991388.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9213..11210)
                     /locus_tag="ACIZD4_002515"
     CDS             complement(9213..11210)
                     /locus_tag="ACIZD4_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991389.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(11308..11583)
                     /locus_tag="ACIZD4_002516"
     CDS             complement(11308..11583)
                     /locus_tag="ACIZD4_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991390.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            11815..12549
                     /locus_tag="ACIZD4_002517"
     CDS             11815..12549
                     /locus_tag="ACIZD4_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5991391.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12588..13730
                     /locus_tag="ACIZD4_002518"
     CDS             12588..13730
                     /locus_tag="ACIZD4_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5991392.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
BASE COUNT         4428 a         2714 c         2125 g         4529 t
ORIGIN      
        1 atagaccgaa gaagtggaaa tatttttctg acgagcgatt tccgtcatgg aagtattctc
       61 ttttaagcga gcaatgacag accaacgaac tttttgacta atgaaacagt gtttttcagc
      121 aacagaggta tccgctacga atgttctttg gcaagactta catttaaatc gttgtttctt
      181 caactccaga taagtgcgat actcagacgc atcattcagt aacaaccgaa cggttgtcgt
      241 cccccaacga atgatcctag aggggacgac acaaagacaa tgggaacact cttctggctt
      301 gtacagaaga gttcctttgt aaatcatgga tttgagtcaa tatcttggac acattttagt
      361 agagacggtt aagccatttt ttcttttgct aattcttcaa attcctgtgg ggttagatag
      421 tgaatcgagc tatggattcg atttcggtta taaaatcctt caatgtagct aaatagcgct
      481 cgatttgctt cttcaaaatc tgagtagcta gtcgtgtaga cttcttcttt tttcaatgag
      541 gcatggaaag attcgattcc agcattatca taaggtgttc cttttctact ataagaatgc
      601 cttattttgt tggttttaag ccattgttcc acttctcttg ctgtgtattg gctgcccaag
      661 tcagtgtgta gaatcattcc ttctggaatg tgataatgta tttttgcttt attcaatgtt
      721 tgaatgacac aatccacagt cattcgtttt gaaaatgtat aactaataat ttttttcgtg
      781 tgtaaatcca tgattgaaga taagtaacac caaccatttt tcttagtagg aatgtacgta
      841 atgtcagctg cccatttctc acagatcgtt tcagtagaaa agtcctgatt taagagattc
      901 tcttttgaaa tgatcggttt attagacctt tgaggtctat attttttaac tacaatcgac
      961 cttaaattta attgtttcat tagcttttgg acatgtttaa gagatactga aatcccttct
     1021 tttaataaaa cttgatggat ctttgtggca ccatagcgtt gtttattcgt aaaaaaaatt
     1081 gttgaaatct tctttttcaa cttattattt ctgatttctg tagctgtcaa cggtttattc
     1141 ttataaaaat aatagacact tctagggatt tctaataacc gacataacaa agaaacagtg
     1201 taatccttac accatttttc aataaattga acaagcgaat ttaggttttc cgagagaata
     1261 tggctgcggc tttttttaag atttcaagtt cctcatttaa acgagcattt tcttttctca
     1321 gttcagctac ttcttttcca gtcagtcctg tggactgatc aggtaaatat aaattcttcc
     1381 atttgtaaat cgttgcttca gataagccat attctttcgc taaccctcga acagaacgtc
     1441 cagtttgatt cagttcaaca atcatttgtt taaaattttc ttcatatcgg gtcataaaaa
     1501 ttcatcctct cgtagataag tttaatttat tcttgtctct acgaaaagct gtctaagatt
     1561 tgatactaac accaagttat ctttagaacc atttcagata catatgaaac aattacatat
     1621 gattttttca taaaaaaaca gtactgtcta gtagtataaa atatacaaat ttcttaaaaa
     1681 ttttttcact aaaatcacta cctgaaacag tctaaaacac ttatatatca acgtttaatg
     1741 aaactatctc cgtttcattt cagatacaaa taaatatagt cgggctccaa atccgaaaaa
     1801 aaataccccc agtagcttat cctaagctac tggagatgta taagtacggt catataacaa
     1861 cggggtaggg taaataaatg aaaaagatgg aagaatcatt attcaataac ttttttaaat
     1921 acttcgttgt aatcagttac ctgtccgttc ttaaatacca cagaataatc ttttttccca
     1981 ttttcaagta accgaagtgg aatgtcttta ccaacttgct ctgtcactgc attactgata
     2041 cctgttagat tagctaataa atctgataaa gattgagcat ctgtagaaat ctctgtatca
     2101 gtatttatcg tgattccttt atcttcattt acaagcttcc aagtaggtgg tatagctgtg
     2161 tatgtttcga tgaatgaatc aattctttca tctatcgtct tcccagtatc tacttctgtc
     2221 tcattactct tagatgaatc gattctttca tccatcgtct gctccgtaac tgcttctgtc
     2281 tcattattct caccggaaac tctcttcaca cccaaactta tatattgtcc atctttagtg
     2341 tgcatagtta aaattcccac gcttttacta ataaattcac tataaccagt tctttcaata
     2401 gagacttcaa tgtatttcac actatcatac tcaaaagaaa aatagacatg taaaagcatt
     2461 ttgttgttta catctacata ataatccttt gactctactt gagaccttcc tatacggaat
     2521 acagctttac tgtctgatat ctctatacca gcatccttat tattaatctg ccaatctcca
     2581 agtagctctt ctggcaagct agtagtttct tgtgaacact ttaccacttc actggtagag
     2641 gtcgaaacat tcacctccgc actgttagaa gaattttcca aggaatcagg agccttagca
     2701 caaccaacaa gtctttatat attgtgcagc cgatattttc ttcattcagt acacccttga
     2761 aatatgcagt gttagataaa gcagttcgtc ctgatttgct gaggcaccca tctcttcttg
     2821 aacgtactcc ttgattttca aggccgcccg atactctttc ggaaaacgct gcttcactga
     2881 agccagcaaa aaatcatcct tctccggcaa ctcttccttc ttaatcattc gggcaataaa
     2941 aaactgtaaa tgcgtcacaa atcttaagta aagcatcgaa tctttatcaa cctttttttc
     3001 gggaaacaga tatcctagca tagccaagat atcctttagt gctcttaccg agagcatggt
     3061 ttcttccata tttgcttgtt cactttgggc atttacaatg tgaaacgcaa tgtttccagc
     3121 ctcctcttct ggcaactgaa cattcatttt tttgttgatc aattggatag catagcagcc
     3181 gatctcaaat tcttttgggt aatacttttg aatttcaatc agcaggcgat tttgaaaaac
     3241 aatgcctttt tgactgcgtt caatggcatg cttcaagtga tcaaccaagg taaaaaatag
     3301 acttttattc agcttaaagt caaacttggc gttggcataa tcgataattc gcttgacgca
     3361 aataattaga tcatccggag cagcctcaaa cagtttaatg taatcctttt ttagagcatc
     3421 agaaagtgaa tctaatttaa atactttttg gattttgtca gccggaacca aatcgccttt
     3481 ctttagttga aatccaatcc ctttccccat caaaattact tctttgcctt gcttatctaa
     3541 gcaaagaatt aaactgttgt ttaacgtttt aattactctc attagattca ccgttctctc
     3601 taagctaagc catttcttgc gattactttt tgataccaaa agaagctttc tttttttatt
     3661 cgttttaatt ctttaagatt ctcatcggtt cggtcaacat atataaaacc ataacgctta
     3721 ttgaagcctt gatgggtact aacaacatca atcgctgacc aaggtaaata accaaaaaca
     3781 tctacaccat ctgttaaagc tgcttgaata gccagaatat gtttggctag ataatcaatt
     3841 cgatcctggt cattaattcg tctatcttcc tcaactatgt cgggtgcccc atagccattt
     3901 tcagtaatta aaataggtaa atcatagcga tcgtacaatt tcctcaatgt taatcgtagt
     3961 ccagtagggt caactaccca gccatatggc gttttatcta cataaggatt ttcagctgcc
     4021 cggtagacac cttcttctcc caacatgatc tgttgatccc ccgctctagc ggaaacatct
     4081 gatccgtcat ttttgctggc agcgatggtg gcagttgaat aataattaat cgcaataaaa
     4141 tcgggtttac cggaggataa aattgcctga tcctctgcct caattttagg atataatcca
     4201 cgatcattca aatagttttc aaacaaataa ttgtattttc cccgaactgc tacatctaag
     4261 aaagaccagc ctctcaatgt ttcccaatta tgggctgcaa ttgcatcttc tggactggag
     4321 gtagcttgat acatagccgt taaattgatt gctggaccga tttttccttt aagattcaac
     4381 tgatgataca agtgaattac tctagcttga gctaataaaa catggtgatt aatttgaaag
     4441 agttcttttt ttgaaggcag ctctccactt ggtggcaaac caatcgctcc aggatgaagg
     4501 atcatcgtgt tttgctcatt aattgtcagc caatagttca ccttgtcacc atactcagta
     4561 agcaatacct gtacatagtc cacaaaataa tcgatagttg ctcgatttaa ccaaccgccc
     4621 tgctcctcta gaaaataagg taaatcgaaa tggtacatgg tgacaatcgg ttcgattccc
     4681 tgattcaggc attcatcaat tacttgatga taaaaagaaa ttcccttttg attggtttta
     4741 ttattttcaa tatccataat tcgcgtccaa gcgatggaaa agcgaaaagc ttttaagcct
     4801 aattctttaa acagctgtat atcttcttta tagtgatggt aaaaatccga ggcaacttca
     4861 aaattagcta ccccttctgt atgctgatac ttgtcaataa tagacggttg tttcccatcc
     4921 tcctgatagg caccctctgc ctggtaggca ctaatggagg caccccataa aaacttctct
     4981 ggaaatgctg aaagctgttt gtattgcaca aaaatcctct ccttaactaa tttgcatcaa
     5041 tggttcgtgt tcctttaagc ttccgcttgc ttcactaatt cctgcgtaat tttcactgtt
     5101 ggtcactacc acaatcactg tatcatcgta gccagcgttt ctaatggcag cgaaatcggc
     5161 gttgattaat aattgtcctg ctgacacctg atctcctgct tttacaaata cttcaaaggg
     5221 ttcccctttt aaattcacgg tgtcgatccc cacatggatc aataattcaa taccttcttt
     5281 agaacgtaga ccaatcgcat gtttagattc taaaatagta atgacttctc cctcaacagg
     5341 tgaataaatg ctgttttctt ctggatgaat ggctacgccc tttcccaata gtcccttaga
     5401 aaagacagca tcgttcactt cagaaatagg acacacggtt ccttttaccg gattttcaac
     5461 aatgactgct tcggctattg ccgtttgctc tgattcatca gaagtatcgt caaatccaat
     5521 tagataagca atgataaagg ttgcaacaaa ggcgattaca cacgtaataa ttgcgtgaac
     5581 aatattcatt ggattttctc caataaaggc tggtaaggct gctaagccag gggaaacaaa
     5641 ggcatatctg actaaaccgc tcaagccagc atacaaacca gcaattgcac caccaatcat
     5701 ggaagcaact aatggttttt tcagcttcaa ggttactcca tagagtgaag gctcagtaat
     5761 tcccattaaa gcagtgatcc cagtggacac agctagctgc ttcaactctt tgtttttagt
     5821 tttcgcggct acagcaaagg tagcacctga ttgagcaata ttagaagcca gcattcctgg
     5881 cccattgatc atttcagaac ccgtactgct caattgcata gtagcgattg gcgtcattgc
     5941 ccaagctgta cccgtaacca ccaaaaatgg ctgcaaacca cccatcaaaa atggaattaa
     6001 ccaagctgct ttgccgttaa tccattcagc ccccattgct ataagatcgt tcagcaacgt
     6061 tccaaacggt ccaatgacaa ccaacgctaa aggccccata attaaaaata ccagcatcgg
     6121 cttagtaaag aatttaataa acgaaggcga aattcgatcc gcaaagggct ctacatagga
     6181 catgatccaa acagtaaaga taatcggtaa aactgatccc gcataatctg cagctaatac
     6241 cggaattcct agaaaagaaa cggcatcgcc agtagaaaaa agctgtgaaa tatttggatg
     6301 aagcaaaatg ccagcaacag taatcgccaa aattgggttg acatcaaact ttatggctgc
     6361 cccataggct aatagtactg gcataaaata aaaggctgca tcagcaatag tattcaaaat
     6421 gatgtaagtt tgactactgt ctgatagtac accagtcaaa gtcaagacgg ccaaaatggc
     6481 ttttaccatc ccggcacctg ttatagctgg aatcatcggt gtaaaggtgg tagaaatgac
     6541 actaatcaat cttgaaataa tactttcttg attgtctgaa gaggggccct ttttaattga
     6601 agttcccact tccttttgaa tttccttgaa ggctgtttgg acttcattgc caatcaccac
     6661 ttggtattgt ccaccgctat ccaccacact aattacacca agtgtttttt ctaaggcttt
     6721 cgtatcggct ttccttttat ctttgagttc aaaacgcagt ctggtggcac aatgggttaa
     6781 gctgaccaca ttttcttttc ccccaacctg ttgcaataca tttcttccta cttctctgta
     6841 atccattatt ctctctcctt aaagcagtaa aaaagaccaa gtcaaaccac gccccaatca
     6901 acattgaagt gttagtttgt cttggtcttg cctgcataat cagtaacatg ccaataacgt
     6961 tattttgctg taatccaata atagcacatt atgatagcgc aatcaacagg gaatttaatt
     7021 ttttatcttt tcgtttgacc gtatagggta atataacagt tagatcacat caactagggt
     7081 atatctgcgt atacttactg ctaaaataag tatatctaat attaactata ccagtaaaac
     7141 cattcctaca taaccagcgg gaaattccca aaatcgtgaa agcatcaaaa atgcatataa
     7201 cggatcacac aacttcaaca attctgctct tgggaaaaat tgatgaattt ggtgagtaaa
     7261 ggatggaata aacagcattc caacaatata ggcaacaata gtgatacttg tttttttggt
     7321 aaaaatcagt aagcaatagc caatttcaat cattccgaga tataaaggta tcgatagaat
     7381 gatttgggct agtattctta aaaattaact agcaaatgtt taaactgatt tatttctaat
     7441 ctacatgtag taagtatttc aattccacca attatcaata aaaataccaa acatatccat
     7501 aataattttt tctttttcat ttcttttata ttgttataac agtgaataac ataaaaattc
     7561 ccgacaatca ttgtaatatt tttttgtcac ctgtattagt atttaattta taggaaacta
     7621 taaaaactcc ctagtgaatt tacacctttg ggagttcctg tttggacggt atgcataata
     7681 catttaaatc aatttaacat taacacctca gcatatggta tctccacata tatacggtct
     7741 ttctttggat agtactcaat atttatgttg atagcacttc cattgtctaa tatagcttta
     7801 gcccggtatg tgttatctcc attttcatga gtaatcgtca catcatcaca tgatcgattt
     7861 aagttgtact gttcttgtaa aatctgtgtt accaatggtt tcgatgactt ctctaatcca
     7921 gatgtacctg tcatttttga aaaaatgata cctataatag ccaagacaac gataactata
     7981 atgataaact tcttgttcat atttacttta ttcaactttt tatctcctat ctccaaaata
     8041 atttgctctt atccctctta tcagtacatt gacatcccta aaagtacacc aaagattgct
     8101 ccagctaccc ctgctatcat caaaatcgta cccatttgtt catctttatc tcgatataag
     8161 tagcccataa taacagcaac agcaccaaat acaacaggaa taaatgctaa cgctactacc
     8221 atagaaatcc aaccaataat caaatacagc ttccctgtct cttgtccatg tacgatttgt
     8281 tccttcattt cattaattgt ctgctcagta cttttcttta ctgcgtctgc tccagttgtc
     8341 tcatctgttt cttgtagtgc tccgcaaaac tggcaatact tactttcatc tgttatttct
     8401 ttgccacatt ttctacaata catgtcttct cctcctaaaa acattcaatt gtttattagt
     8461 taactgttta ctttattaaa tacatcagaa aacagctcat tcattggtac acttaatatc
     8521 tcagaaagca tcttcatttg atagggttta ggaatcgttc tccctgtttg ccacgaactt
     8581 acacattgct gtgtaacatt catttttttg ctaactccgt ttgagaaagt cctttttctt
     8641 ttctgtatcg gctgagatta cttacttttt tcatgattct cccctcctgt tttattatat
     8701 acaacaatat gatgtatttc aactcataaa atataaaaaa acttcaaata ccattacaaa
     8761 tacaacaact tgttgtacta tactgagatg ggggtgtatt aatgaaacag aaacaatatg
     8821 caaaggtcat tagagaaaag cgaaaagctc tcgggtggac acaaaaagaa ttagctgaaa
     8881 aaatcttctc tacacaacag gcagtagcaa gatgggaaaa ttctgtaaca gagcctaacc
     8941 tcgatagctt aaccgctctt tctagagccc taggaacccc tgtaagccat tttctagaca
     9001 atgttgtcgt agattatgag gaagagtttt tggctctcta tcgttctctt agcactgaag
     9061 atgcagttcg aacaattgac tatatgaagc tattaaaaag gcaagaaaat gaacgcaatc
     9121 agctattgaa agattgaaaa ataaataacc caccgaactt taacggtggg tgtattgaga
     9181 tgaaataaga ttaagagcta tggataacct gtctagttta atacaattgg gtcttttctc
     9241 ttccttactc tccgtccatc atctcttgtt acacttgtaa attgataaag aggaactaat
     9301 tcaactcctg ataatatcaa ttcttttatt acttcatcta tccctgctcc ttttgctagg
     9361 tagactaaaa aactactact tgctttcaca ttgtatagtc tcttaatatc cttagaagct
     9421 cgttcaagag tgaatccttg tttaacaaag tagcctctgt tttcttttaa agcattttcc
     9481 acgctgttat tcccaacatt acgtagacgt tcacaaacag tgttagtaag ttctttctct
     9541 gtcattagat atgttccttg ccacgataag ccctgtaaaa cttcatgtgc ttcatctaaa
     9601 atcaattgtt tttccttgct aagttctgat cgggaatttt gaggaaatac tcttttagcc
     9661 tctttttcgt taaaacatat cttaacccat tcataagaaa aatattgata tgtaaaatga
     9721 aatttttcca gaagtggaag gatatcttca ttcaattttt gaatcacaga agttgcatta
     9781 aaaacgtcta atcgatagac attgcttctc ttatgattaa agtttcctaa cgctttctct
     9841 tcctttaacc tatttaggta ttcgagcatc ttcaaaggaa catcttcatc atctaatttt
     9901 tttatcaatc ctataaaagt cataagtgat agtaacttat tacatttatc tatgtcataa
     9961 gttttaccat agtaaaaact cattttttta gctaattgtt cccccgacaa aatacaagtc
    10021 acactttcct tactatcatc aaaaaaatta acatcagaaa gcaagacatc atagacacgt
    10081 cgcatttcct ctagataatt ccttattgtc ctgaaaagtt tgtctttcat tgattcaaga
    10141 gtgtcaaaaa gtacttttga ttcctctttc aattttcgaa aatgtgtagg atacaagtct
    10201 aggttctcta atagccaatt aaatgtttct acccgactgt ctttctttaa aattagcatc
    10261 acaactccaa taaaattttc actgatatca caattactgg aatgacaata aaaaatggaa
    10321 tgcccagttt tactggtaaa aatactagca gagggattat gatcgttgtg aaacagacat
    10381 cttaagtttt tacttgactt aagtaattta ttcatatcaa tggttaacaa tctttcataa
    10441 atctcattaa aagacatgtc ggaggaatca aacaggcagt ctttaaacca ctgtttcatt
    10501 tcttctttgt cgtcattttt tatcaactta acaaaatcgg tttcattgac tagttcatac
    10561 tctctccctg aatcactttg acaattttta gaacatgtca tggtaaaatc aatcggaagc
    10621 tcagtaatat ctaacatgtt gtcttcatta attattatca ctgcatctga cttatatcct
    10681 ccaaaaaaca ttctattcga agcatttaca ttgtcatcac acccggggat gttctttttc
    10741 aagtattcgt aaacagcaac cattttacca tagtcagtaa ttgcttcttt taatagaaag
    10801 acaatcttgt atttttctag attttcagag taccgaatac ttttttgtat cgcaaacgca
    10861 gaattatgaa ctaaattgat agataaaacc ttttctatgc ttaagtatct actatcatct
    10921 ttactcaaat ctactacctt ccccttctca tctttaacag tgttatcgac atccagaata
    10981 attactctgg tttccacaaa actctccttg tcattgcctt tattctttgt cttgcttgga
    11041 ataaatgatt gtgatgaatt tagtatctct acaaactcat ctcttgtaac ttctctatag
    11101 ttatctaaac acctatctct tacatcagtt ttttcttttt ttgtaactgg cttctctaat
    11161 aatttttctt tatctacata aattggaata ttaatcattg atgtttccat ttgtgtttcc
    11221 tccttataaa attctgttaa agactaaaac atacagataa taaaaacaaa ctctttatta
    11281 ctatatgttt tagtcttatt tgtttactca acctttatac cgttccatga aactatcaat
    11341 atcagatttt ttaaatctaa tgaccgtatc aatttttata acaggtaacc cgtattgaga
    11401 aacatatttt ctaatcgttc ctactgatac acctagatat tcacttgcct gctgatagtc
    11461 catatactct agagtgactc cagaaataat gtcttctagc ataggcttta gcactgtaat
    11521 tatctctttc acttgttgtt caacttgtat agaaacaatg ctatcaatga tttgtagaga
    11581 catatttccc cctcctttcg tgattgcttg aacaaatttt ctaagaatta tcttcgtatt
    11641 ttttgctcaa aataaaagta ttttgttatt aaccgattaa tcaaacaaaa aatgattacc
    11701 agttcatcga catacacata atacctcgat aaaaaagagg tgtcaatatc tttgtaaaat
    11761 ttatttacaa cacccctttt tcgaggtata ctaattttag gaggtgtggt caatatgata
    11821 aaacgtccac caataaatta tttagaacga aaaaagatac tcggaacaaa aataaaagct
    11881 ataagaaaga gtaaaaaatt aacacaacca gcatttggtc ttatgattaa caacggtcaa
    11941 ttaattgaca aaaaaactat ctacgaatgg gagaagggaa cctatttacc aataccagag
    12001 cgattatccc gaattgctga tttgggaaat atgagtatag aggagttagt ttgtggcaat
    12061 gtagaagaat atattttggg aattattctt tatagagata gcattgtact agatggtata
    12121 acatttccag ataaaaacct gttccagcat cttcgtcaac agttcccacc agtacactct
    12181 aatttagata catggctgga tagatattcc aaattagaac cagagatgca agaatttatt
    12241 gctaacaaga cttgtaataa agttaaaaat gaaaaaatta gtcttttcaa tatcttaaaa
    12301 atagaagaat tattcatcaa tgctattgta gaagaatttg acaataacat tcttttcctc
    12361 actagcagta tagaagaact actagaaaga atggtagatg aatggctacc tattcaattg
    12421 aaagacatgt cttatcccga agaagctgtg agagaaatta ctgataatat aaacaagcta
    12481 gaacaaacga tttcatcaat tgggaaaaaa tacactaaga aaaaaatgaa gggaggtgat
    12541 accatctagt ggtaagtact ccttgtaaac taagaggaga tgatttcatg gcaaaaatat
    12601 caaagtacaa aaagaaaaac ggtcaagtgg cgtggatgta taaaggacac attgccaccg
    12661 atccacgaac tggtgaaaaa ataaatacta cgagaagagg ttttagtagc aaacaagaag
    12721 ctcaaaaaga ttatgacgag tacagacatc aaatattata cggtgttaaa aagaaagcac
    12781 ctgatatgac atttgaagac ctgtataatg aatggataac tcatcagcgt accagtgtta
    12841 aagcttcaac aatcgcaatc tcagtaagat acgcaaataa tcaaatactt ccagcatttg
    12901 gtaagcttaa actatcgaat atctctgtcc catattgtca aaaagtggta gatgaatggc
    12961 acagtaaata tgaaagttac gattatatga gaaaacagac tgcacaaatt ttacgctacg
    13021 gggttgcaat gcaatatatt gacaataatc ctatggaaaa aacacttctt ccacgaaaaa
    13081 aagagtatga gaaaaatcgt aaattttact caaaagagga gcttaataat ttactggatg
    13141 cttttaaaga ttttggtaac atgaaacaat acgccttctt cagattattg gcatacacag
    13201 gtatgagaaa gagtgaagta ctcgctttac agtggaaaga catagacacg tttaataaag
    13261 aactacatgt caataaaact cttgctgtag atgaatttgg taaagttata attcaatctc
    13321 cgaaaacaag agcttctaga cgagttatct ctttagatac tgagactctt tctatcctca
    13381 acaactggaa attacagcaa aaagaagagt atttaaaact tggatacaat actagctcta
    13441 aagagcaaca tgtttttaca acagttaaaa acactctata cattccaaac actgttaatg
    13501 attggttaag atatattttg aaaaaatata acttgcctcg tattacacct catgggttta
    13561 gacatacaca tgctagttta ttattagaag caggagaatc tgtcaaggta gttcaacaac
    13621 gattagggca tgaaaatagt aaagtgacat tagacatcta tgcacatatt acaaataatg
    13681 cacctaagaa aacaggtcaa gactttgctg atatgatggc tcatcagtaa aagagctggt
    13741 caaaatctgg tcatttctag tatacaggca aaacaaaaaa gctagaaccc ttatat
//
LOCUS       DBBGRF010000071        13660 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000071 DBBGRF010000000
VERSION     DBBGRF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.071"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(14..2011)
                     /gene="tkt"
                     /locus_tag="ACIZD4_002519"
     CDS             complement(14..2011)
                     /gene="tkt"
                     /locus_tag="ACIZD4_002519"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGC5991393.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2113..2364)
                     /locus_tag="ACIZD4_002520"
     CDS             complement(2113..2364)
                     /locus_tag="ACIZD4_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGC5991394.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2511..3134
                     /gene="lexA"
                     /locus_tag="ACIZD4_002521"
     CDS             2511..3134
                     /gene="lexA"
                     /locus_tag="ACIZD4_002521"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HGC5991395.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3314..3532
                     /locus_tag="ACIZD4_002522"
     CDS             3314..3532
                     /locus_tag="ACIZD4_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991396.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3821..4333)
                     /locus_tag="ACIZD4_002523"
     CDS             complement(3821..4333)
                     /locus_tag="ACIZD4_002523"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGC5991397.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4347..6644)
                     /gene="recJ"
                     /locus_tag="ACIZD4_002524"
     CDS             complement(4347..6644)
                     /gene="recJ"
                     /locus_tag="ACIZD4_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGC5991398.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6786..7229)
                     /locus_tag="ACIZD4_002525"
     CDS             complement(6786..7229)
                     /locus_tag="ACIZD4_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HGC5991399.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7230..8018)
                     /locus_tag="ACIZD4_002526"
     CDS             complement(7230..8018)
                     /locus_tag="ACIZD4_002526"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGC5991400.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8015..8956)
                     /gene="rnz"
                     /locus_tag="ACIZD4_002527"
     CDS             complement(8015..8956)
                     /gene="rnz"
                     /locus_tag="ACIZD4_002527"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGC5991401.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9133..9720)
                     /locus_tag="ACIZD4_002528"
     CDS             complement(9133..9720)
                     /locus_tag="ACIZD4_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HGC5991402.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(9941..11254)
                     /gene="obgE"
                     /locus_tag="ACIZD4_002529"
     CDS             complement(9941..11254)
                     /gene="obgE"
                     /locus_tag="ACIZD4_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGC5991403.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11542..12552
                     /gene="gap"
                     /locus_tag="ACIZD4_002530"
     CDS             11542..12552
                     /gene="gap"
                     /locus_tag="ACIZD4_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGC5991404.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12637..13572)
                     /locus_tag="ACIZD4_002531"
     CDS             complement(12637..13572)
                     /locus_tag="ACIZD4_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC5991405.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3752 a         3067 c         2416 g         4425 t
ORIGIN      
        1 caattgcttg gatctatgat agttgattgt acgtattcac gacattttct actgtaaatc
       61 caaattcttc taaaatttta gtgccagggg cagatgcacc gaaatgatcg attgtaatcg
      121 ttgcgccctc tgttcctacg tagcgttccc atccaaatga tgcagcagct tcgatagcca
      181 cacgtttctt cactgattta ggaagtacac tttctttata ttcagaagat tgtttttcaa
      241 agaggtcaaa gcttggcata gaaacaacag aaacatcttt gcctttttca gccaattctt
      301 tttgagcttt cacagccaaa tcaacttcag aacctgttgc aatcaaaata ccttctggtg
      361 tttctccttg tgatggagaa agaacatacg cgcctttttt caccatttca tctgctactt
      421 cttttgtaga aggcaatact ggaaggtttt gacgactcaa tacaaggata gtaggcgcat
      481 ctgttgtctc catcgctact ttccaagcag cacgtgtttc atttccgtct gccggacgaa
      541 tcacttgaac accaggcatg cagcgaacag atgctagttg ttcaatcggt tcgtgcgttg
      601 gtccgtcttc tccgacagca accgagtcat gtgttaagac gtaaacaaca ggagtatgtt
      661 ggattgctgc taaacgaact gctggtctta gataatcgac aaagacaaag aatgttccac
      721 cgtagatacg agttccgcca tgaagttgga taccattcat agccgaagcc attgcaaatt
      781 cgcggacacc gaaccagatg ttgcgtcctt cataatgttc aggagtgaaa tctttatctg
      841 cagccaccat tgtattattg gaacctgaca agtccgctga accaccccag aagcttggta
      901 tagctttcga taattcttgg atgacttctt tacttgaaac acggcttgct tgactgcttc
      961 caacttcata agttggcaat tctgcatccc agttttctgg tagtttgcca tcaaaagcat
     1021 cttcaaattg ttgtgctaat tcaggataag cttttttata attggcaaac atttcattcc
     1081 atgcatcttc agctttttgt ccttcttcta tcatcgtttg atggaagcgg gcagctactt
     1141 cttctggaac agtgaaatct ggatactccc aaccataaac ttctttagcc atcttgatgc
     1201 catcttcacc aagaggagca ccatgaacag cagatgttcc ttctttagga gcaccatagc
     1261 cgatgactgt ttttacttcg atcaatgttg gtttgtctgt ttcagctttt gcttcttcaa
     1321 tcgctttaga gattgcttct aggtcatttc cgtctttcac taagatatgt tgccagccat
     1381 atgcttcata gcgagcacca acgttttctg tgaaagcttt tgaagttgga ccgtctagtg
     1441 aaatatcgtt tgaatcgtat aaaacgatca atttccctag tttcatatga cctgccatcg
     1501 aacttgcttc ttgagatacc ccttccatca agtctccgtc accgcatatt gcatacgtat
     1561 agtgatccat cacattaaag ttttctttgt tatacgttgc tgcaaggtgc gcttctgcca
     1621 ttgccatacc gacagccatt gcaatccctt gtcctaatgg ccctgtagtg gcttctacac
     1681 catctgtatg atgtacttca ggatgtcctg gtgttttaga atcccattga cggaattgtt
     1741 tcaaatcatc gattgtcact tgatagccag ctaaatgaag caagctatac aacattgctg
     1801 acccatgtcc tgccgaaaga acgaaacggt cgcggtcagc ccagtttttt gatgtcgttg
     1861 gatttacttt caggtgtttt gtccataacg catatgccat aggtgctgcg cccatcggca
     1921 atccaggatg tcctgagttt gctttttgga ctgcttcaat acttaatgta cgaattgtgt
     1981 taacgccaag ttggtcaatt ttgtcaaaca aaataacccc tcctattaat ttaggttttt
     2041 tttaccttta tttcttacac tttcattcta taagatgtca cacgaaaaag caatcttttt
     2101 cagtattttt tactaaaagt tgtcatttcg gttgtgtaag ccttttttct tttggatttc
     2161 ttttaatttt tccggggtca cgtcattgcc ctcaggatcg acgactttca ttccttcgat
     2221 atgatgacgc ataccggaac gaaaagcttc caaatactct ttgcgcaagt tgatttgttc
     2281 ttgttcttcg gcttttgaga gaccattttc cttcttttta cgtgcaagtt cattgatccg
     2341 ctctattttt tcaggtgaca gcatgctcag ccctcctttt actctccttc atattatata
     2401 aaaactgaaa aaaaaacaac tagataaact aaataaaata cgaacattcg tttgatttag
     2461 cgctttttat atggtactat ttatttatca agtgaaagaa ggtgtacctt gtggcccgac
     2521 aaactgaatc aagacaaatc gaagtcttac gatatatcca tgaacaagta acccaaaaag
     2581 gatacccgcc gactgtccgt gaaatcgggg aagctgttca gctttcttct acttctactg
     2641 ttcacggtca tcttgcacgg cttgaaaaaa aagggtttat ccaaagagat ccgacgaaac
     2701 ctcgtgcaat cgagttgaca aaacaaggtt tagaaaagat tgggattcgt ccaacaacta
     2761 ttccagtact tggcgtcgta acagctggag aacccatttt agcagtagag gatgcttcag
     2821 acttctttcc aatccctcct aatctttctt ccgaagaagg cagtctcttt atgctgacaa
     2881 ttcgtggaga tagtatgatc aatgctggga tattggatgg tgacaacgtg atcgttcgga
     2941 agcaagaaac tgctcaaaat ggcgatattg tcattgcaat gactgccgag gacgaagcga
     3001 cttgcaaacg attctataaa gaaaaaaact ttttccgtct gcagcctgaa aacgacttgc
     3061 tcgaaccaat catcttagat caagtatcta tattaggacg agtagtagga ctttatcgta
     3121 gtcatatcta ttaattgcta ctaattaaaa gaaaactttt taaaaagagt ttgagacgtt
     3181 ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc acttccctct
     3241 ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc ataaattaaa
     3301 gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg ttttgttttt
     3361 aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg ttccgttatt
     3421 tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc ggcgcagaat
     3481 tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat aataaggatt
     3541 gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga caaaaatcgg
     3601 tcacatcctt tttttcgaat aaacggtgtt ctaaagccag tttttcggta ttaagtcaaa
     3661 ttgcggaaaa agtgattttt taaacttcta ctggtctttg cttgtttcca tttataaaaa
     3721 aatagcgacc ctcaaaagtc agatagagaa tctgactttt gagggtcgct ttaaaatcgc
     3781 ttctttaaga ataacatcaa gaatagcttc ttttttctgc ttaatattcc attaatgtaa
     3841 tgatgtcata tcctttgatt ttgtcgcgtc catggagatc catcaattcg atcaaaaatg
     3901 cgcagcctac gactacaccg cctaattgtt cgatcagttc gatcgtcgct ttgattgttc
     3961 ctccagtagc tagcaaatcg tcacaaatca gcacacgttg acctggttta atggcatcct
     4021 tatgcaatgt caatgtatct gttccatatt ctaatccata agtcacttcg atggtttctc
     4081 gaggtaactt cccttttttg cggactgggg caaaaccgac tcctaactca taagcaacag
     4141 gacatcctac gatgaatcca cgggcttctg gcccaactac catatcaatt cgtttttctt
     4201 ttgcataatt tacgatttgt ttagtagctt cccgataagc gtcaccatct gccatcagtg
     4261 gggaaatatc tcgaaacaca attccttttg acggatagtc gggaatactg gcaatataat
     4321 cttttaaatc cactctttgt ttcctcctag gttgttaacc atttctttat ggtaggaata
     4381 tcgctcaaaa gcaaaaattc ctcaactttg attttattga gccgtcgctg gtataatctg
     4441 ctctcagtca aaggatgact ttctgggcta gcgacttttt gtaaaacacc gttctctatt
     4501 gtaacaaatt tcaattcaaa aaacacctgt atcataaaaa ttaataattt ttcagggata
     4561 cgcaaatatt gagctattgc ttttatttta tgacgtatat caattcgttc ttgagaatgg
     4621 atcaatttaa acaattttgc gtactgttct cttgtgccta ccccattcaa ataggcctca
     4681 tcaggtgaaa tccccatcag ataaacacga ttgaatgaat aagaccgaaa aacttctttc
     4741 agatccgcta aatcatctgg acaatccata acaactagag agtttggttt tcttttttca
     4801 attattgcct ttacagaatc tagtccttcg aaaacaatcg cagcttcctg gataatctca
     4861 ggcacgaatt tcaacgtcga agaatcaaat gctaaataaa ggctaccttc cgacgttcgg
     4921 ctctgttcac ggaaacgttt tgcccgccaa tcaaatactt gcagaccacc cacagaaaaa
     4981 tcagatacca tcagctgcgg tttcttacgc ccgttccatt cattgatcga aagctttcct
     5041 accacatcta cctgattatt cagcagttct tcttcttgag taccaaaacc aaaagcgacc
     5101 gcatcaagct gactcgatgc atcggaaagg acaaatttca gatgctgttg gtttgctccg
     5161 attcttttga tattttctgc ttggacttgt cgaaataaaa actgaggcaa aggattatcc
     5221 gtaccaaatg gcgccaatag tttcagctca tcaattcgct ctactgttac ttcatttggc
     5281 agcaatactt catcaattct caactcaggc cctctcatca agtcaatttg atgatcgact
     5341 atatattggt tcatcttctc ctgtagtata gtgacatttt cacttggcat cgttaaaccg
     5401 actgctgcat gatgtcctcc gaagtaagta aataaatctc gcatctggtc aagcatttca
     5461 aaaagattca aggcttcaat actacgtcca gatcctttag ctgatccatc ttcttttaaa
     5521 gtaaggacaa gcgttggttt acccgtttca ttcattattt tcccagcaac aatgcccaaa
     5581 acgccttcat gccatcctcg gtttaccaat agatggatat gattctcctt attgaccatc
     5641 gctaatgctt cttgtgttat ctgctctacg attgcttttc tttcttcatt gatctcattc
     5701 aatttttttg cttgaacgga tgcttcctct tcatcaaacg tcgcaagtaa cgagacggca
     5761 ggacgtggat cgcccatccg accgattgca tttagtctgg gagcaatcga aaaaccgatc
     5821 gttgtttcgt ctgcgtccct catttttacg ccgctttctt caaatagcgc ctgaagtcct
     5881 atccgttctg aatgatgaat ggcatcgatt cctaatgaaa caaggattcg attctcatca
     5941 gtcaatgaaa ctaaatcggc gatcgttcct atcgctacta aatccaaaaa ttctgcaggc
     6001 ggttcttcca ataatgcaga agctactttg aatgctactc cgactcctgc caaatctgga
     6061 aatggatagt gccccgctgg atgacgaggg tgaacaatcg cataagcgtc tggtaaattc
     6121 tcaggtagtt cgtgatgatc tgtaatgatc acgtctacac cagcttgctg agcgtatgct
     6181 accgcatcat ttcctgctac cccgttatca acagtgatga tcaactggat tccttcttcg
     6241 atcttttctt ggtataccga ttggtttggt ccatacccat gctcaaatcg atttggcagg
     6301 aatacttcta cttctgcacc aagtaattcc agtgtttctt tcattaccgt tgcactggtg
     6361 atcccatctg cgtcataatc accgtaaacg aggatttttt ctccactgat tacagcttct
     6421 tggattcggc tgattgcttt atccatatcg tgtatcagat acggatcatg taattcttgt
     6481 tcctttggat gtaaaaatcg gttgatatcc ttttcctcat ggtaacctct ttgccacagt
     6541 aacttaccga caaatggaga taatttcagt tcacggatca tttggagaaa ggattcagaa
     6601 ggctctgtct cgcttaactt ccaatcaaaa tttgcttgtc tcactttctc actcctaact
     6661 tagttattat agcaaaggaa atcagcaaaa aaaagcagaa agaaagaata aaaacagatc
     6721 agatccgcta gacagatgtt cagcaggacc tgatcttttg tacgaccatt tatgaaatat
     6781 ccctattagt caaaataatt gaagctttgt ttgggcgatt gagttttttg ttcttccggc
     6841 gctttcaatt gactgatttg tgcggttttc gcttgtaact ccgcctgata agcagcttcc
     6901 aactccgcac gttcgtttct aaactcgcgt tgctgttctt cttttgcttc ttcaattttc
     6961 ttttgaagtt ctgtttgata ttctgacatt tcctgagtca gctgtttgat ttgctttttt
     7021 tgctgccata gtgttgccga agcagtcaaa aatacaatca gtgcaccaat cagcgcagaa
     7081 ccgatgatca ctaagatcaa tggcgcagaa aaggaagtga agccaaaact tacaggaaca
     7141 tttttattgt tcaatacagc aaaaagaaca ataatcaaaa ctaaaacaaa tccaagaatc
     7201 acattgcttt gctttttcaa ttccttcacc tactttttgt taaaaattcc gctggctaaa
     7261 taatcaccaa tcgttggaaa cagcgtataa aattttgatg caacttctaa aataaacggt
     7321 tgattgattt cccgttttgg atgtctcata ttgcggacga tcatttttgc caacttggca
     7381 ggttctaaaa cgatttgtcc gactttttcc aaatagcttc cgcttggatc agccttatcg
     7441 aagaaatttg tctcgattgg acctggattc actgtcgtaa cagctacgcc aagtggtttc
     7501 aattctaatc gcaaagcgtt ggagaagcca aggactgcaa atttcgtggc agaataaacc
     7561 gttgattttg cagttgccat ttttccagcc atagaggcga tattaatgat atgaccttgt
     7621 cttctttctg ccatatcgat cgcaaatttt tgtgtcaaaa ccatcattcc taagatgttg
     7681 acttcaaaca tatcgtatgc ttttccaagg tcgaatgtaa ggaagtcttc gaaaatccca
     7741 aaacccgcat tgtttaccag aatatcgacg cgcccgactt cttccatcac cttttcatat
     7801 aattcgtcca cgctttcagg attgctgacg tctaccttga aagcataagc ctctttgccg
     7861 ctcaagcgtc tgcactcgtc tctgacacct tctacaaatg ccattcttcg tgcgcaactt
     7921 ataacgattg ctccttgctt tgctgcttca taacagattt gtgcgcccag accgcctgaa
     7981 ctacctgtta ctaaaacaac tttatcttct aaattcatgc ctcttcctcc tcgcgaaatg
     8041 gaatctcaat gctatcaaaa tctttcataa tcgtcgtgtt ttcaaacact tcttgtgctt
     8101 ctttttcaag ctctaaagct gcttttccta aatatctcgc actgatatga gtaagtagca
     8161 gccgttttgc ctgcgcttct tttgcaactt cagcagcttg atgagtcgtg gaatggaaat
     8221 agttgtgcgc cattcttgct tcatctttat taaatgtgct ttcatgtacc agaatatcgc
     8281 tattttccgc aagcacaacg gaattatgtg tttttctcgt atcgcctaaa atagtcacga
     8341 ttcgtccttt tttatctgga cctacgaaat cttttccatt gatcgtccgc ccatcttcta
     8401 gttggatcgt ttcaccttgc ttcagtttgc cgtacagtgg tccagctgga atacctaatt
     8461 cttttagacg atccacctgc aattctcctt tatgatcatg ttcaaccaca cgataaccaa
     8521 aactgtcgat cccatgattt agtttttttg tataaacaga aaattgctga tcagtaaaaa
     8581 tcggggctgt ttcatttagc tcaatgaatt tcagcggata acttaaacgc gtttgcgaaa
     8641 tacctaaaga gacttttatg tattcctcta tcccttttgg cccgtaaatc tctaatggcg
     8701 tatccccacc ttgaaatgac cggctgctga tgagcccggg aagtccaaaa atatgatcgc
     8761 cgtgtaaatg tgtaatgaaa attttaccga tttttctcgg acgaatagtc gttcgcaaaa
     8821 tctgcatttg cgtgccttcg ccacagtcga acaaccaaac ttcattgcgc tcgtctaaaa
     8881 gtttcaatgc tatacttgtc acatttctat gttttgcagg aacacctgca cctgttccta
     8941 aaaattgtaa ttccataatc tacctgactt tctttaagtt cctctttaat tttagggtaa
     9001 aaagaaggga taatcaaccg taagtcgaga atgggttcaa attaaaaata acgttctaaa
     9061 gcgatagcgt tttctttgaa aattactata aaaacagcag cgaacccgtt tgagatcctc
     9121 tgctgttttt tattaatttg aagatccaga actttcattg tcgttggaag tttgcggatg
     9181 tttgtccttc caagtctttt gtgcagcttc tttcgcatga ttttcagctt ctttcgcatc
     9241 atgcacatct ttttcgacat cttcataatc caagcgagta atttctccgc ctaattccat
     9301 cattaccaat tgattcagtg ggcgattgtc ctcttcatca gcaatcaaga tcagtcctgt
     9361 agctccttca ccgattttat ttcctacaaa gtcgaacacg gtctgggcat cttttatttc
     9421 tttggcatct tgtgtcgcac cgatcattcc tccggcaaac catcctaata aaatccctag
     9481 cggaccacct aatacaccaa ccaacattcc gattaatcca cccgtagaag atttgttatt
     9541 accggtaaag tcgataaaat cttctatttt gaattgatgt gtcccattag gatcatggct
     9601 gacaactgcc atctgttctc ctttaatcga acgaacagca tgtaactttt tgatttctga
     9661 aaatgcctga tatgcctggc tttctacttg aaaatttaaa atgattactc gtttgctcat
     9721 taaaaacgcc cctttcatac cttcttgtta tttattttac ctttaattga aaaataagaa
     9781 aagaaaagca ctcttttttt ccaataaaat agggctgtga caaaagtcgt atcacagctc
     9841 ctttttccga ataaacggcg ttcttgaagc tgatcacttc tgtcacaacc tcccttaaat
     9901 ctgaatctat attttttggt atttgttttt atttgcttgc ctattcgaca aattcaaatt
     9961 caaactcacc gatacgtaca aggtcgccat ctttcgcacc gcgtgcccga agagcttcat
    10021 ccacacccat accacgtaat tgacgagcaa aacgcatcac tgtttcatca tgatcgaaat
    10081 tcgtcatttg gaataatttt tcgatcttct caccagataa gatccacgtt gcatctgaat
    10141 cacgatcgat ttggaactca ggaccttctg gattgaatcc atagtgtaca gtttcttctt
    10201 ccagttcttc ttcgtacaat gggaattctg gcgttacttc taacaaatct gctgtagcat
    10261 tcaataacgc gtccaatcct tgtcgagtca ctccagaaat tggaaatact gggatgtcat
    10321 cagcaaattc atcttctttt tccttgttca gctgttcttt gaatttcact agattttccg
    10381 gtgcatccgg catatccatt ttgtttgcca cgatgatttg cggacgctct agcaagcgta
    10441 agttataagt agataattct ttgttgatgg caagatagtc ttcataagga tctcgtcctt
    10501 ccatcccact catatcgatc acatgtaaaa ttactcgtgt tctttcgata tgacgaagga
    10561 attgtgtacc cagcccaaca ccttgcgaag ctccttcaat caagcctggc aagtctgctg
    10621 cggcaaaact tctgccatca cttgtagtaa ccattcctag attaggtacg agcgtcgtga
    10681 aatgataagc gccgattttt ggacgagcag atgaaataac ggatagtaaa gtcgatttcc
    10741 cgacagatgg aaaacctaca agtccaacgt ctgccaatac tttcaattct agttcgattt
    10801 ttcgctcttg tcctggttca ccgttttcag caatttccgg tgcaggattc cgaggagagg
    10861 caaaacggat attccctcgt ccaccgcgtc caccttttgc cacaactagt gtttgaccat
    10921 tttcaattaa atctcctaaa agagcaccag tctccgcatc tcggacagtg gttccttgtg
    10981 gtactttaac ataggtatct tctgaaccac gaccgtgcat ccctttactc atcccatttt
    11041 cacctggctg cgctttgaaa tggcgattga accgaaaatc catcaatgta cgtaaccctt
    11101 catcgacgat caagatgaca tcgccgccac gaccaccgtc tccgccagcc ggtccgccgt
    11161 caggaacgta tttttcgcga cgaaatgcaa ccattccgtc tccgcccttg ccagctttca
    11221 catcgatcgt tacttgatct aaaaacatgg acataattaa gtcctcctat tattcattta
    11281 tttatttgac tgcctgaatt tccacaataa acaaaagtct tacttatttt atcggtgaaa
    11341 tctgattttg tctatcattt cagcaaaaag attgtttacc ttcttctttt tttatcattt
    11401 ggtaaggttt ccaacctttt ttctgctacc aagtataatt ttttgacaaa atattctttg
    11461 cgtagcagaa taacagtgta ttaattgtat taattgagga tgccgtttca cagcacccct
    11521 aataaaggag gaacttttga tatgacagta aaagtaggta ttaacggatt tgggcgtatt
    11581 ggccgtctgg ctttccgccg catcaaagaa gtctcagatg atattgaagt agtagcaatc
    11641 aacgacttaa caagtccaac tatgttagca caattattgc aatttgactc tactcatggt
    11701 acttatcctg gcacagttac tgcaacagaa gactcaatcg tagtggatgg cgaagcaact
    11761 cgtgtttatg cagaacccga cgcaagcaaa atcccttggg caaaagaaaa cggtgtagat
    11821 atcgtactag aatgtactgg tttttataca tctgaagaaa aagcaaaagc gcatttagat
    11881 gctggtgtca aacgagtagt tatttctgcc ccagctggtg ctatgaaaac catcgtctat
    11941 aacgtcaatg atgatacatt agatgaaaac gacaaaatca tctcagcagg ttcatgtaca
    12001 acaaactgtt tagcacctat ggcttatttc ttaaataatg aatttgggat cgaagttggt
    12061 acaatgacaa cagttcatgc ctacacttcc acacaaatgc tcttagatgg acctgtaaaa
    12121 ggcggtaatt tgcgtgctgc tcgttcagct gctgacaata ctatcccaca ttctactggt
    12181 gctgcgaaag caatcggctt agttatccct gagctacaag gaaaattaca aggacacgca
    12241 caacgtgttc cagtcgttga tggttcatta actgaattgg tttcagtatt gaaaacaaaa
    12301 gtaactgctg atcaagtaaa cgaagcaatc aaaaaacaca cagttgacaa tccttcattc
    12361 gggtatgatg accgtcaaat cgtttctagc gatgtcattg gaacaactca aggttcgatc
    12421 tttgacccaa cgcaaacaga agtaacaact gctggtgatt tccaacttgt taaaactgtt
    12481 gcatggtatg acaatgagta tggatttact tgccaaatga ttcgcttact agaaaaattc
    12541 gctaacttgt aatttgatag atcaatcgat aaaagaagcc tttgactgga tccagtcaaa
    12601 ggcttctttc ttttcatccc ctacttttaa actcgttcaa tgaacatatt ggcttaaaaa
    12661 ttgttggact acttgctgat atttttcagg atctgtcttg tatgcttccg catgctcggc
    12721 tccttttaca acatactttt cttttggtcc cttcgttgca cgatagacct tatctaacat
    12781 ttcaaatggt acaaatgtat cttcgtctcc atgtataaag agcattgggc gctggttttt
    12841 cttcaattgt tccactgcat ttgcttcacc gaaaaagtag ccagcacgga cttttgtcac
    12901 tagactcgtt acttgcataa gcggaaatgc tggaagacta aacatatcgt ctagctgata
    12961 agcaagctca tcatgaacgg aagaataacc gcaatcttca atgattgctt tcacattatc
    13021 tggtagtttt tctccgctag tcatcataac tgttgctgct cccatgctga caccgtatag
    13081 aacgatttct tgcgattttc cattgttttc tagcactttg tttatccact gtacatagtc
    13141 tttacgctct ggccatccaa atccaatgta atccccttcg ctttttccat gtcctcttgc
    13201 atcaggaaca aggacattgt aacccatatc atgaaacatc tttgcgtaat tggtcatcgt
    13261 ttcagcgttt cccatatagc catgagccac aagagctgtt ttttcacttt tcgtttcagc
    13321 aggaagataa atcgctgata atttcagacc gtcttttgaa gtgatggtcc aatcgcttcg
    13381 gttttctttt gaactaaacc atttatgtgc atccgtttct ttggatgtct gtgttgtacc
    13441 aggtgtatct tcgtctaaaa agtctttctc agaaggcaca acagcataat tataaaaata
    13501 attccctgca aacactaacg caacaatcag agctaaagcg acgcctaaaa ggattttcat
    13561 ccaaagtttc ataaatcatc catctcattt ctcttttttc atataacctt gaattagtat
    13621 aatcaaagaa tctctactat gcaatgttca tttttataac
//
LOCUS       DBBGRF010000072        13344 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000072 DBBGRF010000000
VERSION     DBBGRF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.072"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(43..1362)
                     /locus_tag="ACIZD4_002532"
     CDS             complement(43..1362)
                     /locus_tag="ACIZD4_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5991406.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1359..2012)
                     /locus_tag="ACIZD4_002533"
     CDS             complement(1359..2012)
                     /locus_tag="ACIZD4_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC5991407.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2300..2820
                     /locus_tag="ACIZD4_002534"
                     /pseudo
     CDS             2300..2820
                     /locus_tag="ACIZD4_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(2818..3537)
                     /locus_tag="ACIZD4_002535"
                     /pseudo
     CDS             complement(2818..3537)
                     /locus_tag="ACIZD4_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(3488..3697)
                     /locus_tag="ACIZD4_002536"
     CDS             complement(3488..3697)
                     /locus_tag="ACIZD4_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991408.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            complement(3679..3747)
                     /locus_tag="ACIZD4_002537"
                     /pseudo
     CDS             complement(3679..3747)
                     /locus_tag="ACIZD4_002537"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            3974..5247
                     /locus_tag="ACIZD4_002538"
                     /pseudo
     CDS             3974..5247
                     /locus_tag="ACIZD4_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5354..6385)
                     /locus_tag="ACIZD4_002539"
     CDS             complement(5354..6385)
                     /locus_tag="ACIZD4_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5991409.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6392..7222)
                     /locus_tag="ACIZD4_002540"
     CDS             complement(6392..7222)
                     /locus_tag="ACIZD4_002540"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5991410.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7219..8034)
                     /locus_tag="ACIZD4_002541"
     CDS             complement(7219..8034)
                     /locus_tag="ACIZD4_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5991411.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8031..8855)
                     /locus_tag="ACIZD4_002542"
     CDS             complement(8031..8855)
                     /locus_tag="ACIZD4_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HGC5991412.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8845..9945)
                     /locus_tag="ACIZD4_002543"
     CDS             complement(8845..9945)
                     /locus_tag="ACIZD4_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGC5991413.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10123..10908
                     /locus_tag="ACIZD4_002544"
     CDS             10123..10908
                     /locus_tag="ACIZD4_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HGC5991414.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10941..11324
                     /locus_tag="ACIZD4_002545"
     CDS             10941..11324
                     /locus_tag="ACIZD4_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HGC5991415.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11400..11531
                     /locus_tag="ACIZD4_002546"
     CDS             11400..11531
                     /locus_tag="ACIZD4_002546"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC5991416.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11500..11736
                     /locus_tag="ACIZD4_002547"
     CDS             11500..11736
                     /locus_tag="ACIZD4_002547"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC5991417.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            11748..11834
                     /locus_tag="ACIZD4_002548"
                     /pseudo
     CDS             11748..11834
                     /locus_tag="ACIZD4_002548"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(11814..12785)
                     /locus_tag="ACIZD4_002549"
     CDS             complement(11814..12785)
                     /locus_tag="ACIZD4_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HGC5991418.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4055 a         2912 c         2305 g         4072 t
ORIGIN      
        1 aagtctctat ttttcaataa ctattgcaaa attatatctt aattaagaaa atatttttat
       61 tttaaagata aaaaattctt catcctgcaa tactttatat tctatattgt aattattcag
      121 aatattactt acaatatata aacctaatcc attactattt tccttattta aatcaaattt
      181 aacatcaaat attttatcca tattcgaaat tttattgtta ccgtatgaat tctctatata
      241 taaccaatca ttaactatcc caatattaat taccccattt acatcagtat attttaccgc
      301 attactaatc aaattagata gaataatctt taaagctgtt tttcctatat aaacattctc
      361 gtctaatata taattattga cagttatttt cttttgattt gctaatattt catacttttt
      421 taatatgtct tctaatgtat catttatttt caaatattct tcatcattat tcaaattttc
      481 tatagaatga actgataata tttgagaaat attttttgtt aaactatcaa cgatttcaat
      541 acattcatta atataaatat ctctttcttt atattttcca atattgtatt tcatgttttc
      601 cagtattatt ttaagactag caagaggggt tttaagttca tgggatgcac ctttaaaaaa
      661 gtcatatttt aacttttcta attttaaaat ttctttattt ttaaattcca aatcgtcaat
      721 tgttcttaat aaagtagaat acaaatcatt aatttgttgt tttaattctc caacttcatc
      781 attagagcta acttttaaac tcattttttt atcaagtttc atcattttat cagtaacaat
      841 ttttatttct tgtatattat tttttattga ttttgcataa attaaagaaa taatagcaga
      901 aaataaaatt gatattaata aagaatatgg taaaaattta aggcttaaat ctttcgcatc
      961 tttttgcata tcagctgtag aaacaaattg tagatttgtt tttttaccat cattaagctt
     1021 tatttctctt tcttcaatta tcaaagaatt actatcactt tctaaattaa catttatatt
     1081 atctttgatt tgtatttcat tcttattatt tttttctttt atgaatactt ttatttcact
     1141 actcttggaa taaaactcca aagtttgttc tatatatttt atttcttttc cattcatatt
     1201 actagaaatt tcatttgcca tattatgaat cttttctttt ctcgtctcca aatatgtttt
     1261 aggaaagata aaaaaaatta atgaatgaac taatataatt attattccaa gaacagaaaa
     1321 tatttgtatg aacatttttg gaaatatctt taattttttc attttctctc caatttatat
     1381 cctacatttc ttatagtagt tatacagtct aattgtaatt tttttctaag ttcttttata
     1441 tatacatcta ttactcgatc ataaggagtt tcttcgctat ctttccatac ataatcaata
     1501 atttgcattc ttgttaacac ttgtccatta ttatccaata aacattttaa tacttctagt
     1561 tcttttgcat ttacatctat ttcttcacca tttattttag ctgtatagct attaaaatta
     1621 accgatagat ccttatattc aaacttctct aaatgtccat aattcttctt aattaaagaa
     1681 tctattctag cttttaagac cggcaatgaa aatggctttt ctacatatcc gtctactaaa
     1741 ttagtaaatg catcaatttt atattcttca tcactaaatg cagtcaagat tagaattggt
     1801 aaattgcttt tctttctaat ttctttcaac acttctaaac catttataaa aggtatctga
     1861 atgtctaaga taaccaaatt tatatcgcta ttaaattttg acaaggcttc tcttccatct
     1921 ttagcttgaa taacagtata tccaaattct gaaagatatt cacttattcc ctctcttatc
     1981 atattatcat cttcaacagt taatattttc atatatacct ccacttaagc ctatacacta
     2041 gatattatac agcatattat ggctctataa tatctagtgt tggtgacgcc ttctgttgcc
     2101 aatacttttt ctttttttta ataaatgcaa acagacacct tgaaatcctt tagaaaaaag
     2161 gcttctataa tattttgtgt tgttggaaaa tcgaaggcga ttttctacta acactttttc
     2221 ttcgtttcaa ctcaaaaaga gactcacttt tggtaaaatt tagtcgacca aaacatcacc
     2281 ctaccaaagg agtcgctcta tggataatca tactagaaaa ttactcggat taacagataa
     2341 acatttattt tttgatgaag aatggctgat tgaaaaagaa tataaaggcg ttcaagcgca
     2401 gtttattaaa gggagattgg atgactcacc ttcccattgt gaacactgtg gatcgattcg
     2461 tattatccgc aacggttcct atacgacacg tactcagatg ttgaaagtca aagaaaagtt
     2521 gactatttta gaattaaaac gtacccgttt tctatgctat gattgtgggc agaccttttc
     2581 tgcgaaaacg gacttagttg atgaacatca tcaactaaca aaggaactga agcaggcgat
     2641 tctcatagaa ctgtacgaaa atcaatcacg taatctgaaa atcagaagaa gtaccgtcgg
     2701 ctcaagcgat attggaaact cttactcaaa gattccacga cattggagcc gctcaaacgg
     2761 cattatcatc gactgtttaa acgaccaatt agtcaaacag aaatcgtcga tgaaccgttg
     2821 tgcacaatgg tgtcctgaac gtacagcgac accttccata tccagagcag tcgccacatc
     2881 acggggatgg atgccatcca aattaaaagc aaccacgcca gtatgatgtt caggatcttg
     2941 cggtccgtaa atggtgatac cgccgatcgc ttgtaattta ggtaaaacgt aggcaaccag
     3001 ttcttgctca taacgatgaa tattctccat accaatctca ttcaagtaat cgattgctcc
     3061 tgcaatgttc ggagtaccag cttcaaattt ccatggcagc tctttccatg aactatcgta
     3121 aagattgaca aaatctatca tttcaccgcc gaattcgact ggctccattt gttctaacaa
     3181 ttgacgtttg ccatataata caccgattcc tgtcggcccg cacattttat gcccgctaaa
     3241 ggcgaaaaaa tctgcatcca acgcttgtac atcaactgtc atatgcggtg ctgcttgggc
     3301 accgactgga ctatcctcaa ctacaacagc ctgttcaacc ctcagccgtt tcaagcacaa
     3361 caaataacct tctggatctg gtttgccgac ctgaagatca tcgatcgtca caaaggaatc
     3421 aattttttcc ttaatcatcg gatgtgcttc aaaaaaatag tctagctccc gcagttcaga
     3481 attgagacta ctccgatttt ccagtgctgc tgatccgctg ctcaaaatgt tcagcatcca
     3541 ctggtctccc aaccgcttga cttatccctt cataaaagga cagttctgct gccgtcccaa
     3601 caccttgttg atagtctgca aaaggaattt tatagccgaa ctgctccagt aaataggctt
     3661 cagtaaatag tgatgaatac tctcgtaaaa catccattca ctgtcaatca tcgtcccatc
     3721 aaaatcaaaa ataagtgctt tggtcatctt ctttccccct tacccaaaac aagcaaaagc
     3781 tgtgtcctgc tctctctaca gtatcagcat aaaaactgcc gtctgaaaag tcaaaggtga
     3841 aagaaatgtg gcgctataat ttctaggact gatagtaaat cattctatca gtccttttga
     3901 gcataaaaaa acaaaacata cagaagctcc gttagaattg aatcaccaca acacaatcaa
     3961 aggagcgttc tgtatgcctg atcttcatct tatcaaacta ttactaggaa tcaaagatgg
     4021 aaacattcaa atcactcatg tcgagaagaa aaaaatacat tcaatcaaca gtatcgttgt
     4081 ttctgccacg ctcattaaaa cgattcagcc ctgtcctcag tgtaaacagg tgaatcaaca
     4141 tgggctgatc gttaagaacg gaaagaaaaa atcgctggtc cttctcaata agtgtgcgaa
     4201 tcaacggact tatcttgctt tggcaaagca acggtacctc tgtcgtggct gtcacaccta
     4261 ttttacggcg aatacctaca ttgttgaaaa aaactgtttt atcgccaaac aagtacatta
     4321 taaaatattg gaggaattga ctgaaaaaca agcaatgacg acgatttcta aacattgcgg
     4381 cgtttcttgg tcaaccgttt cgcgaacact cgcttctctg ctccccatga caaacgtgaa
     4441 aataaattgg ttgcctcgct gttcattggt agatgaattt cgttcattga aaaatcaagt
     4501 cggtccctat tctttttctt gtatggatgg cgatactggg aaattactgg atattcttcc
     4561 ttcacgtaag aagaaagatc tcatttctta ttttatgcaa tttgaacgac gtgcacgttt
     4621 aaacgtaaaa atactcgtaa cagatatgaa cgcctcttat gctttgctga taaaagagtg
     4681 ctttcctcat gccaaactcg ttgtggatcg ctttcacatc gtcaagcacc tcattcgcag
     4741 ttttaaggat atttgactat gagtcatgaa aagcttcgac cgaaacgatc caatacaagc
     4801 caaacactat cgacaagtga aggctttatc tcgacttctg atcaaacgac aggacacgct
     4861 tgtttatgat aaatggacaa aatggcgtaa ttttggttgg gcctatttaa ccgaaagtga
     4921 agtcgtagaa cgtctacttt ctacttctga tgaactacga atagcttatg cttactatca
     4981 agaaattctt caagcttttt atgacaaaga agcggacatc ttctttcagc ttgtaaaaac
     5041 aatgcccaag tcggttccaa gagaactgca tcatataaaa aaagcgttta taaactatga
     5101 atccggcatt cgtttagcct tagagttgcc ttactcaaat ggcaaaatag aaaatctgca
     5161 tacccacatc aaagcattga aacgaatagc ttacgggtta ggatgagaac cagaattttc
     5221 ttaatcaatc atctgatcac ttattaaaca taaaaaaaca tctaaagcag aaaatcaatt
     5281 ctaccttaga tgttcttata tcactctatc agtcctattt gacaaagagc cagaaatgtt
     5341 tgccgactat acactagctt tgttgtgcaa aatgctgagt atcaatttcc acagggattg
     5401 ctagaatatc tttcaactga atgtataagg catcgctaat tttctcttcc cgatcgttca
     5461 accgatccac taaaatttct ttgccctcca gcgtttgaaa aacataccgt tgaatgttgc
     5521 ctaaaataaa tgattccttc catagaaccg gaatcttaac cccctgagga accggttcaa
     5581 attgaatcag ctccggtctt aaataataaa tgcagcgatt gcccttagcg gaaaactcgt
     5641 gggtatactg attcagctca taccattcga aacgattata gttgccgata aattccgcaa
     5701 caaatcggct ctgaggattc tgatacaatt ccttcgaggt ggaaacctga gccacccgcc
     5761 cagcttccat cacaaaaatc cgatcactga ttcgcatcgc ctcttcttgg tcatgagtca
     5821 caaaaatcat cgtcatccct agcgattgct ggatagcgcg caaatcccgc tgcagctgtt
     5881 ttctaattcg ggcatccaaa gcacttaatg gctcatccag cagcaggact ttcggttcag
     5941 tgaccaatga gcgagccagt gccacccgtt gtcgttgacc gccagaaaga aactggacat
     6001 ttttatctgc ctgctccgtc atatccacca atgatagcat ctcaaaaacc ttttcctgaa
     6061 tcacctcagg actcagcttc tttaccttca aaccaaaggc tacattttca aaaacagtca
     6121 tagttggaaa caatgcatac tgttgaaaaa caaagccgat attgcgatcc ttcgtaggct
     6181 tatcggcaat attctcattg tccagcacaa tctcaccgct ctttggttgt tccaatcccg
     6241 tgatacagcg cagcaacgta gactttccgc acccgctggg acctagtaaa gtaaccagct
     6301 cacccttttc aatctgaatt tcatcaatag ctaaaatctg tttttcatca aaaaacagat
     6361 tgagatcatg tatttctaaa aacattttcc gtcacaactc ctttaagggc ttctttttcg
     6421 actgcttctc ttccctcgtc tgcttaaggg acagctgttg cttttgtcga taagtcagca
     6481 taaaggtagt taaagcaatt cccaccataa acagcaaata caaaaccatc acagcgctag
     6541 ccaaatggcc gttttcgttc atccgccgca gcatatagat gcgtaccgtc tgaaatcgac
     6601 cgccaatcaa caggttcgtc agcatgtact ccccaaaaac cgaagaaaaa atcatcagag
     6661 aaactagggt cacaccgata cggatgtttg gaaacagcac ctggataata atcgtagaca
     6721 tcggggcgcc caaggtttct gctgcatcca ctaattcctt cagattaatt aagcgcatct
     6781 ggttgttaag actaagatag acaatcggca acgccgtaat aaacaatgca cctaccaaca
     6841 ctacaaacat tgggatacca gtttcagcat acgttcgaag caaagccgtt accaaaatca
     6901 ctcctggtaa agcatacggc agcaggagca gcttttccag ccaacgattc aaacgaggga
     6961 aatacaaatg aatccaaata atggtgggaa tcatcaacaa cagaatcgtc accaagacca
     7021 cacctgctaa taaaagtgag cgacccaccg cagcaataaa ttccctgtcc gtcagcagct
     7081 gttggaacca ttgcaaggta aaatcactag gtaaaagcga ttttgaccat ttagtggagc
     7141 tggcatacaa aatcgttcca ataatcggca gcaagtaata caggacaaag cagaacaaaa
     7201 tcggttttat taactttttc acgtctgcac caccttgcct ttcttttgaa taatcaacat
     7261 tgccgttacc agcaggacac ctaaagcgac tgccaacgca ctgcctaaat taggcttggc
     7321 gaacacatct cccgacacta aagccgcaat tcgaatcgtt aaaagattta cattactgct
     7381 ggtcagggca tacgctgttt cataggtccc catgccatta gcaaataaga tgacaaaggt
     7441 gctggcaatc gatggtcgca aaaaaggcaa agccaccttg aaccaagcat acgctgatga
     7501 agcgcccagc aattgtgcgg actccagcca ttcctttttc acttccttca tgctgggata
     7561 caaaaacaag acccctaacg gaatttggaa ataggtatac gtgatggtca atccccacca
     7621 agaatacaaa ttgaagtccg ctagaaatgg caaaatcatt ttcagcacac ctacattccc
     7681 caacaaaata ataaaagaga atgccagcgg aatcccagca aaattagctg ccaaattgga
     7741 aacaaaggtg attttctcct gcaatttagt cgatagattc attaagcata aacataaaat
     7801 aaacgtcccg attaacccaa tcacactgga gctgacagca atcagtacgc tgttaacaaa
     7861 ggcctgtgtg taatatttgt tgctgaaaat atcactgtaa ttggccaatg tccactggtt
     7921 agttaaatca ctgtgcaagc tgcacagaac cataaaaagc agcggcagca gtaaaaatgc
     7981 acagaagata aaggaggcag gaaccagaac caagcgtttt ttcatctctt tcatcccctc
     8041 atcaattctt gaatgtcctg cattttctct gacggtgcaa ttcctaataa ccagcaaaac
     8101 aatggagccg ccagcagctg tggtacagtt tgttccttca gcttttggcg tttatttgaa
     8161 atcaaataaa aaggaacttc acgatgtgca gccaagctgc cgccatgcag tccgtgcgca
     8221 tccatcccgt gatccgcagt caccacgact tgataacctt tttgcagcca ttcaggaagg
     8281 taaatagcca ataatctgtc cgcctgatta accgctgctg catattcatg agaatcggcg
     8341 gtaaatttgt gaccgacatc atcaatattc atcgaatgta cgaccaaaaa gtctggctga
     8401 tactgattca ctaaataatg ggcatccgca aataaatgcg aatcagggta agtgtcctca
     8461 ctataaaaga tgccatgctg aatcagtcgc tcctcctgat gctggatgcg atcaaccaaa
     8521 cgattatagg gggcttgatt gtacaactcg ctgtaccagt ggtaagcggc ggctcctgtt
     8581 tttccgccag cttccttaac taattcaaac agcgaccact ctttggatcg ctgagcatgg
     8641 taattactat agatgccatt ttcataggct ggaacgccgg tcatcagtac ttcgtataac
     8701 ggacgtgaat tgctgggcag ctcacttttt accttcaata agcttgcttg ctggtgctca
     8761 actaaatgat tcatgaaccc aagctgggcg acggctgtgt cgtagcgaca gccgtctagt
     8821 ataactacaa tcagtttgtc aagtctactt tgcataggtc agtacctccg cctgccaaag
     8881 ctctggaagc tctacagagg tcttgttcca agcttcattg tcttcaactg gcaccgccgc
     8941 ttcataagca tcctccggca gtaatttttc agctacttct ttaggcagct ctaccttgcg
     9001 aataggtcgc gcatagccct ttgccaaatt gatttgccct tcatcagata aaatatattc
     9061 ccgtgctagc tttgccgcat tgggatgagg ggcattttta ttgattaagg ttgtataccc
     9121 gctaatgatg gagccgtctg ttggcacagt tacctcaaaa cgctcggagt caatttggtc
     9181 acgataattt agtccattga agtcccaaac aactgccaca tcgatttcac ctttttcaag
     9241 atttgctacg ctggcatcaa cggtggacaa acggcctttt tctgccattt ttttgtagta
     9301 attcagacct ggctgaatat ccttttcgtc acctccgttg gcaatcgccg cagccaatac
     9361 agcaaattgt gcttggttgg caatcgtcac atcccccacg ctaacttgat agtcaccctc
     9421 ttgcagctcc ttccagctag tcggtgcttg cttcacattc tctttatcgg tgataaagga
     9481 aatggttccc gtatagctta acaaccaatc cccatcatca tcctttgccc aatccggaat
     9541 ttcctcccaa tagttggtct tataaggtaa ggttaactct ttgctttcag ccaacggacc
     9601 gaagctgata ccgacatcac caatatcggc ggttccattt tttccttctg attcaaactt
     9661 agccaattct tctgcactgg acatatccgt atccacgtga cttaagccgt attctttttc
     9721 aaggtcgttc caagtgccta cccaatttgc ccaagtatcc ggcattccca agctggcaat
     9781 ctctccttct tccttggctt tttctataat cgtatctaaa gagtcgtctg ccgcagccga
     9841 ttgcttcgtt gcttcacctg agccgcagcc tgtcagcagg atacttactg ttgctgcaca
     9901 aaataaaccg atagtcatgt tacgaatttt ttcattcatt ttcattcatt cttctcccct
     9961 ttcgataatt ccattctaac aaagctttgt aatgagagaa tcagtttctt gaaaaggttt
    10021 catgaacaat gtaaaggttg tatatggttt gtaaatttcg acgaattccc gttaaccttc
    10081 taaagctttt gcggtatgat agtagaaaaa aggaggctcc ctatgcagta ttatgatcag
    10141 catctccaca cgtatttttc ctttgattca gaggaaaaat ttgaaaacta tttagcctat
    10201 cagccggagt ttttcgtttc tacggatcac tttgatttaa acaatccatc taccggaaaa
    10261 gatgacattc cggattatcc agcctatata aacaaactgg actctttaaa agaaacctat
    10321 tccaccaaat ttctgcgagg tatcgagatt ggcgttgttc caggacaaga agagcggatc
    10381 gtggattacc tcgctcagca tccttatgat ttaaagctgg taagtattca tcaaaatggc
    10441 cgctttgatt atatggacga tgtggtttta accaaagatc ccattcaaac taccaaggaa
    10501 tattttgatc agatgttgca ggtcttgacg gattttccag aaggagatat tttgactcac
    10561 tttgattatg gattacgccg cttcaccttc acagcggaag aattcgcgga gcattttgag
    10621 gctcagctgc taacgatttt caaaaaggtt gttgaacgag aattggcgat ggagttaaat
    10681 gccaagagct tcttgaaata cggcaacgaa gacctttacc gttatgccgt tcctttgtat
    10741 caaagtgtcg gcggaaagct ctttacctta ggctcggatg ctcatgttgc cgaagattat
    10801 cagctgggct ttaaaaaaat gagtcagctg ttggcagact gtcaggtaga aaagttgcta
    10861 gtcattcaag gaaaagaacg ccgcctgacg ccgctgccga ttttgtgatt cctatataat
    10921 agaagaaagt ggtgaaaaaa atgagcaacc tgtgggacta caatcaagag gcacccatcc
    10981 attatttaat tgcgcgacat tgggatgcgt tgaaaattga ggcggtttgc cgatccttgt
    11041 tagcagccgt tccaaaacaa caactggaaa attttttggt ggctgacagc ttgcagcggg
    11101 aaaaagttca ggcttatttt gcagccttta aagatcagcc tttggaatat ttgcatgcgc
    11161 agtttcatct tttttatcaa gtagccgccc cagatgacta caacgattta cgaggacagc
    11221 tgcaattgac ctttcaagcg gatgaaaccg cctataccgt tttattggga atggctcgcc
    11281 ttggtgatca ggcgaaggtc gagtggcgga ttttcgatat ttgatggcag gatcaaggcg
    11341 tttcagttgc aaaccttcct ctctttcaat tagaaaaacc gcagcaggaa gaagtttgtg
    11401 tgctggtcac cgatgctggt gaaattcgtc tccgcttatt tcctgaccaa gctcccctgg
    11461 ctgtagccaa ctggcgctcc ctagctgagc aaggcgttta tgacaacaca cctttcggct
    11521 cgtgtcatta aggaatttgt tattcaaggt ggcgctttgg atggttctgg tgatgaagct
    11581 gtttccagct atgagggctt tttcgctgat gaagtgcatc gcggacttta tcattttaat
    11641 ggcgccttgg ccttagggga ccacggcccc cacaccaacg gcaaccagtt ttttattgtg
    11701 caaaacacaa aggcgcaggc tgacctgcta atgtaaagca agcatacttg gagcttggag
    11761 gactaccgga gctggatggt cgttatactg tttttggaca ggtataccaa gggttagaaa
    11821 tcgtagcagc gatcgcagct cagccgacaa acagtgaaga tgtaccgatt gagccagtgt
    11881 tcattcgaca aattaacttc gaaaaaacat cgtaaaaaga cactcactga cttcagcaaa
    11941 agctctattc ttgagctggc tgcagctagt gagtgtcttt catttatcca taagataaag
    12001 cttggattca ataaataaat aaatgttttg gttaaagctg tgaccagcaa atgaggaacc
    12061 gtgcgagcca gttgatctgc caatgcaaac atttctttag gtgaaggcgc tggcgtgtct
    12121 gccaacggat actccagtcc caatgcttgg taaccgtgca taccatagca gtggtacggt
    12181 agtaattcta acggtacgaa ccgatcaaga tctgccacaa aacaagcaat cgtcagcagc
    12241 tcggtcaggt tcatattgat acctggaacc acaggaactc gaattcgcac ttcgcagtta
    12301 ggatactcaa ttaaaaagcg acgaatattc ttcaaaattt gttggttatc taagccggtc
    12361 cattgtttgt ggagcttgct ggtaaacatt tttacatcca caaacaatgt atccacatag
    12421 ggagctacct tttggatttc attataagca ccacaaaagc tggtttccag tacggtattg
    12481 attccaatgt atttcgattt ttgcaaaatt tctttagcaa aatccgcctg aaccagtgcc
    12541 tcgcctccgc taatggtcac tccgccatcc gagtgaaagt aaaaaacagc atccttctca
    12601 atctcatcca ttacctcttc agcggtcatg gtctggccaa atcctttttc aatctgcttg
    12661 ctttgtgatt cgggaatcga acaccaggca cagcgtaatg ggcagccctt taaataaaca
    12721 acggtccgta aaccagcacc atcatgtaga gaaccctgtt ctattcttaa tactgttcct
    12781 tccatataga tttttgaatt acacactagt ttaaactaaa acacacaagg aaaaacttac
    12841 catttaatca taaaattagc tcatataaat atactaggat gtaaaataga ctggtcaaaa
    12901 tctggtcaaa aaagaggact aatacaggta gtcctctttt ttgttatttt aatattctaa
    12961 atcatttttt attggtttat tcccttattc gatgtagact caaatcacta tatcactaga
    13021 tatcaaacgg cgtcatacgg aatcaaaaac atcaaatttg acctgttaaa tggtcattga
    13081 ataacattca aaatcaataa aacggagtca gacacggagt caaaaacgct gagagtaaaa
    13141 aatatataca gccttgtagg taaagtacca cagggctgta tattttttat ttcagattac
    13201 cttaaatgat tccatttact ttttatctca ttttttccta ctagttagta tcaaatactc
    13261 tcctattttc tcaataaact atttttggat acatggtatc tgaaacagct aaaaccttgt
    13321 cattacagca aaaaatcacg ttat
//
LOCUS       DBBGRF010000073        13089 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000073 DBBGRF010000000
VERSION     DBBGRF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.073"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            104..1147
                     /locus_tag="ACIZD4_002550"
     CDS             104..1147
                     /locus_tag="ACIZD4_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HGC5991419.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            1320..1544
                     /locus_tag="ACIZD4_002551"
     CDS             1320..1544
                     /locus_tag="ACIZD4_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991420.1"
                     /translation="MNQRRRKRLEEISERLSKLKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            1547..1804
                     /locus_tag="ACIZD4_002552"
     CDS             1547..1804
                     /locus_tag="ACIZD4_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991421.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            2021..2896
                     /locus_tag="ACIZD4_002553"
     CDS             2021..2896
                     /locus_tag="ACIZD4_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991422.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            2906..3700
                     /locus_tag="ACIZD4_002554"
     CDS             2906..3700
                     /locus_tag="ACIZD4_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991423.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            3729..4847
                     /locus_tag="ACIZD4_002555"
     CDS             3729..4847
                     /locus_tag="ACIZD4_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991424.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            4880..5200
                     /locus_tag="ACIZD4_002556"
     CDS             4880..5200
                     /locus_tag="ACIZD4_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991425.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            5455..6144
                     /locus_tag="ACIZD4_002557"
     CDS             5455..6144
                     /locus_tag="ACIZD4_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HGC5991426.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            6181..6348
                     /locus_tag="ACIZD4_002558"
     CDS             6181..6348
                     /locus_tag="ACIZD4_002558"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991427.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            6368..8002
                     /locus_tag="ACIZD4_002559"
     CDS             6368..8002
                     /locus_tag="ACIZD4_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991428.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDSHVNMSLTIKRIYDLLYVYKH"
     gene            7974..9200
                     /locus_tag="ACIZD4_002560"
     CDS             7974..9200
                     /locus_tag="ACIZD4_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991429.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            10050..10445
                     /locus_tag="ACIZD4_002561"
                     /pseudo
     CDS             10050..10445
                     /locus_tag="ACIZD4_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            10523..11562
                     /locus_tag="ACIZD4_002562"
     CDS             join(10523..11020,11023..11562)
                     /locus_tag="ACIZD4_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611651.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGC5991430.1"
                     /translation="METERQIRELEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLLHRLGLSWTRPTYTLKKADSKKQQVFLE
                     ETFPSLKKLLNSDIDHLLFEDETMIRDYQAIGCTWFLRGHQRKIPTYGQHKGVKLIGT
                     LDYETGRIICTEEGAYDAAAFLRFLERTLREYPTGKIVMVLDNALIHHAKLIQSFLEE
                     NARRLALIFLPPYSPQLNLMEGVWKWLKESVINNVFFDHVQKIKQSVRGFLADVNERP
                     LEVIDRLCVRM"
     gene            11575..12513
                     /locus_tag="ACIZD4_002563"
                     /pseudo
     CDS             11575..12513
                     /locus_tag="ACIZD4_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            12506..12853
                     /locus_tag="ACIZD4_002564"
     CDS             12506..12853
                     /locus_tag="ACIZD4_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991431.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            12850..13032
                     /locus_tag="ACIZD4_002565"
     CDS             12850..13032
                     /locus_tag="ACIZD4_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991432.1"
                     /translation="MNIIKKYEFGYITYEQLIEELWGYGQQLINEVGIDCFCFYIESG
                     AGYHKNRYYIFPYPPK"
BASE COUNT         4970 a         1786 c         2675 g         3658 t
ORIGIN      
        1 caacaacgat tatgatctta aaacaatcgt ttatgtaatt ggcaatctta cgaataattt
       61 tcatgcaata atgacaataa aaaatgaaaa ggggtaaaat caaatgaaaa aatttttagt
      121 aggaattcta ttcacaatgg ggctagtatt attatcacct tcagtttcag cagaaagctc
      181 tatttccatg tatcgtatgt ataatcccaa tagcggagag catctataca ctagaagcgt
      241 tggagaaaga gacaatctga aacgttatgg atggcattac gaaggtgtcg catggcaagc
      301 tccaacaagt ggtactcctg tttatcgttt gtataatcgg tataacggtg aacattttta
      361 cacagttgat gccggagaaa gagataagat ttcacacaca ggatggacgt acgaaggtgt
      421 tgcgttctat tcctacaacg gagcaaatag agttcctgta acacgtttat ataacaaata
      481 cgtgaattgg catcactaca cgttagatca aaatgaaaag aacgtaatta gtaaacaagg
      541 ttggaagatt gaaggtacag gctggtatgc aatgccaaac agcgtaccaa atcctacacc
      601 tgctccaagc actgaaaaag tgttgaacgt tcctgttgta tggcaaggaa atacaatgtt
      661 atgcgaagga gcttctttat tagaaggttt acactacaaa ggtgtagcca caaatcaaag
      721 cttaaccagt tttgtaaact atatgccaaa agctaatgac aataatcctt atcatggtta
      781 ctcaggagag tggcgtcata acgttaatgg aacgtatcaa ggcatgatgg ctgacccagt
      841 agttaaatgg gcaaaaaacg ttggcggtaa tgccgtcaat atcactggtt caggaacgaa
      901 tggaatcaag aatgaaattc gcaatggtaa tccggttgta acttggatta cttataacta
      961 tgctacgcca gagttcaaac aaatgccttg gggtcgtgca gtatggaatg gacatgtagt
     1021 tctcgtggat ggcttcagaa atggtgcata ccatgttgtt gaccctgtat ttggcgcaaa
     1081 atggatcaat gcaagcacgt atgagagagc atttaatgtg actggaatgg cggttgctgt
     1141 acgttaattg atagaattat caactaaatg aaataagagc ttaattactg aaatggtaaa
     1201 taggctctta tttttttaga ggaaattttt gtaatacgaa tctataacaa aaaatattga
     1261 atgtagtaca caaaagtggt atattaaaat cgtagagatt atgcgaagag gtgattttga
     1321 tgaaccaaag aagaagaaaa aggttagaag aaataagcga gcgactttcc aagctaaagg
     1381 atgagttaga agtaattcaa gaagaagagt acaaagaaaa tatacctaaa aatctacagg
     1441 gatcagaaag atatgaaaaa gcagaagaat ccgttgatca acttgaagaa gctgttgatg
     1501 gtttatccga catattagaa ttgattgaag atatagctag ctagagatga ttaatgaaga
     1561 tttcaggagt gagaataaaa tgattgatat ttcactgata gagaagctac ttttttcaaa
     1621 taagtacaca gccaaagagt tggctacaag atggcaaata tccgaatcag ctattaaagc
     1681 ctatcgtcaa aataagggaa gcgtaggatg gcgtgattgg aaaggaatca gcattggaaa
     1741 agcagaagac ataatgaaac gtgaaggatt tcaagctgac aatgattcta aaaaagttga
     1801 atagtttaat agtcgccaag aaaagtacca ggacgagggg aaaggtagat tacaaaggaa
     1861 aacactttta aataaacttc gcaaaagcat caggttatga gtggctaggg ctatacgaat
     1921 gtgatgaaaa caaagggctt taatgtcaaa gaaaacgcaa taggggggga acaaaatttt
     1981 taaaaaagat atttatgttt ggtttaatgg aaaaaaatat atgactacta acaaaaggtg
     2041 gtcagagcta gtacaaaata cagttaaaaa agtcatgcca gatggatatc atttcaacta
     2101 tatacaatgc tcacaaacaa ctgaaagtat ttatttttca atattaaatg agaatagact
     2161 ctattatttc agggtaagtt cacaccatag gaaaaagaga gaagataatg ttacgacatt
     2221 tttatcggga aaatacaatg gcttcaaaga gttaagtgaa gccattggtg agtatctaaa
     2281 aagtaataga tttgtcagaa tttctgacaa acatatattg atcttgttac tttatttgaa
     2341 taatagcttc aaattgtttt ggagagacga cactttctac tatattgaga acggcatgga
     2401 tatttattct ggtatcaacg gcatattaaa acattatatt aaggcgttac ttcgatatgg
     2461 ggttctttat caagaagatt taagtaacca aattaagatt agtaattctg gaaagtcatt
     2521 actggcaaaa tataaaaaat tgctttctcc tatctacaaa ggaatagata tggaagctgt
     2581 aaattctgaa actttattta atttagttgt tgatgaaaag tttgcgaatg aattttttaa
     2641 aagtaaaaaa attgaaagac taaataacct gtttcctgaa aatgcaataa aagcttatgt
     2701 agataataat aaatcacgat tatacaactg gtttattccc aaacggttgc gaggaaaaat
     2761 caaaattggc gatcaagtga aagtaattaa tctaaatcat actaagatcg ttaccgtaac
     2821 ggagttgtat atagctgaaa aagaagatat tacaaaaatg aaaccagtta ttaaaatact
     2881 agataacaaa gagtgagtgg aatatatggt agcaaaaaag aatactctaa aagaagcttc
     2941 tgaaaaatat caagatatga aaagacgagg attaatacca aaggacaaaa aaggtatatg
     3001 gagagaattt gttaaggaag tcagtagtga tcgaagtggc ggtgactttg ttggacgata
     3061 tacagcaaaa ggttatagca ggcgcttaag gatcactgtt gaatatggaa cgaatgaatc
     3121 agctacagag ctgaagcaaa ggtacttaga tacacgaaga gaagcttcaa aaaaatatga
     3181 tgatttcaag agcagaggtc taattcctaa gaagaaaaag gggatttggc gtgagttttt
     3241 caaagaagaa gatagcaatc ggaataaggg agacttcatt ggacgataca cagcaaaagg
     3301 ctacactaag aatttaggga tcaaggttga atacggaact ggtgaaagtt catgggaatt
     3361 gagaaatcgc tatttaaata cattgttaga gaaatataaa gcagaattat tggagttgtt
     3421 cgatgttaat gattttatcg agatggctga aaagtatggt catgaagaag gttttatgat
     3481 caatgacatt atggttattg ataattttac ggatttatta gcacttgcga aaaaagcaag
     3541 ggatttaaga gaaacgcaga tgtatctatt cagaaataaa aacggaagaa accggagaac
     3601 tgaatcgagt gagattgaag attactatga tgcctttaca cacgatctgg gagcctttgt
     3661 agacgagata agtggtgtaa tgaacaaata tagggtctag aataaaaaag ccggagatga
     3721 gcagataaat gggaaacaat agcatataca cacctgaaat gcagaataaa attaaaagac
     3781 ttgtcggatt agggtggatg acaagaggaa aattagattc ttttagtacg atcaaatatc
     3841 ttttgatgga catttaccgt cagaacaagc aaacaggaat acattttttg ggctatgata
     3901 agccggaaga tgcacctttc tttgttccaa gttcagccta tagagccagt acctccggta
     3961 gcatgtataa cttggatttg tttgaggaag gagcaaagat gatcgaatat gatttcaacg
     4021 aagcctattc gaggatcatg agaaattatc ctttgccgtc aaacacttat ttgaaagcaa
     4081 aatataatac agatcaagct attttgagag cgataaatag accaaaagta agaccgtatg
     4141 aaaatttaaa aacgtatatg ttctttttgg ttaattttga aggaacagcc aaagaaggaa
     4201 catatgctaa tccaaaatca cagtcgatgt ttgcggatta tggcgaaaat cccaaaacag
     4261 ctaatgagcc tatttggtta tcggagattg agctaacact tatccttgat tattatgata
     4321 ttaaagagat ggaagtccta gatagccaca catttttgac gaaaaaagga ttactcaaag
     4381 aatattttga aagaatcgag ccattaaaaa ctgatcctga tacgttgaag ctttataaaa
     4441 atcttagaac gaaagtattt ggtgctatcg gacaaaaatc attaagagaa ggagaaacaa
     4501 gcaccttcga taaatacagt atgtataatc gagcgtattc ctccatggta gcaggcgtat
     4561 ttagagatcg tatggttaga tatgaacaga aatacgttca tagcgcatat gggctattaa
     4621 aaattcgtac tgatggattg tatttcagat ccgaagtacc agagtttgaa gagctgtata
     4681 aacttggagt agttaagaaa aaagttcata caatatccaa agaagaagtc gaaaaagctt
     4741 tagaatttaa aaacaaagga tttgaaaata agggctcctt tgggaaatct aaagatgaag
     4801 ttaagggtgt tgtgatagac gatgatttcg agtttgattt tgactaaata ctctttggaa
     4861 aagatggtag gaggtaaata tgaagaagaa aattgtggaa ggaaatgtag gtgttattat
     4921 tctaaaagat tcaactgact atgctaaatc aatggcacta aaagacgaaa aagttgcacg
     4981 catggataaa gatttagttg aatttctgat ggatgataca gaaagattaa aaggggatca
     5041 gtttttgagt ttaatgaaag acaaaggctt aaacacatat ggtttatttg attataagaa
     5101 attagctata gagtgggtaa aagaaggaga aatatttttt attgaagaat gggaaggtac
     5161 tgagaactta gttcttcatc agtatctttt gaaagcttaa tctaagtaaa acagttctga
     5221 ctagttatgc ttgtcagaat ttcaaaggaa gttttccata accatcatca ttcaaaaata
     5281 aaggatttga aaataagggt tcctttggga aatctaaaga tgaagttaag ggtgttgtga
     5341 tagacgatga tttcaagttt gattttgact agattttttt gcaatgttta agagtaaaca
     5401 aggtaagaac taagatcatg aagattgaga gtaaagaaga tagaggacga atgtatgaga
     5461 acacactata tttatttaga agataaaatt gtagatgaaa ttccggcaaa aagtcgagaa
     5521 caagctagaa aattatttat tgaaaaatac aaagagatca atggagatag tgaagttcca
     5581 aaagtggtcg taacagttag aaaaaggcaa acaaaaaaga gaagtacgtt tcatgtcagc
     5641 cctgatatat ataatcttat agagcgacat agaagtgaag ataatatttc tatctctcaa
     5701 tatattgcta cagttattga tgaattgatt tcaggaaagt atgactatgc ttttgatttt
     5761 gagggtgaaa aggattacaa aagtgttgct gtctttcaat ctgattttga gaagctaaaa
     5821 aactatgctg gcaggagaaa tgttaatttt gcaagactac tagaagagtt ctactccgaa
     5881 gagttgggag taggaaatga atacaagaga gaaacttatg cgaaattgtc tcataagtta
     5941 tcccaagcgc ttaaagaagt gacagaagtt aaagcggaac tagatgctaa acttgaagaa
     6001 gtgaaaaaat atcaaacaga gaggaagaac aacatgaaga atcaagtgga atttgacgaa
     6061 cagaaagaat ttgaaaaagc aagaaaacgc tataacaaaa ttatgaatga acttagctat
     6121 gaacacttaa cagttcatga ataattgagt gagggtacag aaaaatatac gatcgcagat
     6181 atggttaatg aagtggaaac tcttttagct tctttctttg aaaatggtca cgtaaacgat
     6241 gaatggcgaa aagaagaacc taaaagggtt aacgcttata ttgctcgatt aaaaaggttt
     6301 attgataaat ataaggagaa tagtgacaaa ttttctaaag ataaataagg agagagtgtg
     6361 attacatttg ccagaaatcg aaggaatatt ttcgccaaaa ataggtaaaa aacagttaga
     6421 tttcagcagt tttccgagcg taaatagaga ttataatcta ggtgatgagg tacagatact
     6481 aaatattgat ttcaaagaac tagacttcgc tgttgctgtt tccaacaaac ccaaggcatt
     6541 ggaacgagtg aaaaaaatat accaagagaa tgatcaaaat atcaaaaata tgatcaaaaa
     6601 gtatagacga gataattcaa aagttgaaga cgttttattc aacggtacgg caaaacatga
     6661 tttgaatgtt tatatggcat taggagtggc tttgtactgt aattcaatta atcagacaga
     6721 tattttggtt aatatcgtga ggaatagcta tcaaaaaata ttaaaaataa gtagcgaaac
     6781 aaacccttat tatgcaatga aatatcttgg ggataattta ttaaatgata aaaaattgat
     6841 gcacaacact gaagagctgt tatctaattt ggctgcgatt aactttctat tcaaaacagg
     6901 ttctgaagat tattttatag ataacgtact aaaaggtgct tacggaacag cattttatcc
     6961 gctttacaat atgaaacagc ataaagccga acaaaaggat aacaaacttg aaattaaaaa
     7021 gatgaaagaa ctattaggta taggatttgt aaaacccaat tcaaaagtca ctattgcttc
     7081 gttagcaact actaacaatg atgggaaaat agtaaatggg tttgacgatt cagatataga
     7141 tatattgtca aaatcatatt tttctttgta tggagatttt gcagatttga tgggtattga
     7201 tagttactta gtcaataatt ttgagatcaa gggtagcgag ctgaatgata ttgtgtattt
     7261 cgttttaatc tctctatatg caattgatca gaataccgag taccgacaaa ttgactattt
     7321 gctagttttt tatagtttgt tatatcagtt cgttttaact cggttgttta aaaatgctaa
     7381 ggaagaattg atcctgaatt ctgattatga aatagcaaaa caaattgcaa gtattagaaa
     7441 agaaaacaaa tctgaagtaa tcaaattaag aaaagaatta agtattgcga gtaaagaaaa
     7501 cggtcggtta gaatctttag tcaaatcggc aaaaaaagaa gaggaacttt tgaagcaaga
     7561 gattaaagaa ttaaaaggaa tcagaaaaga acttgaacag ctgaggtttg aaaataaagt
     7621 attaaagcaa ttgcaggagc aagaacatag acaatcatta aatggtaaaa ctgaagagcc
     7681 ttcactgtct gaaatgatag cttatctaaa acataaaaac attcttttag tgggaggaca
     7741 tgtaaatttt caaaataaat taactgaact attaccaaat attaaaatgt ttgatgtaag
     7801 cgaaaataat ggaaagatac ttaaaaattt gaatacgtgt gatgcgattt ttctatatac
     7861 agattacttg aatcatggtc tatattatcg tgttatgagt gaaatttcta ataaagataa
     7921 gatattttat ttggacagtc atgtgaatat gagcttaaca attaaacgta tttatgatct
     7981 tttatatgtt tataaacatt aatgaggtgc taaaattgac aacaataact atgacaaaaa
     8041 aaatagaagt atatgttgat ggatcacaag aagaaaggga ttcctttttt gatttttttt
     8101 ggaaaaatag tagagaatat gtaaaagcgt tgaatctggt atataaacag ctaatgtttg
     8161 aagagttgat aaaagatgca attaaagaaa tggatcaagg ttatgctgag agagaagaaa
     8221 gtattcaaaa tcggattgaa aagttagcat atactgatcc aatagatcaa aaaaaacttg
     8281 ataaagcaaa agctgaatta tctaaattga gaaatgaaaa aaataaagaa gcgagagaaa
     8341 tattaacgca agcgataggg ttgaagagtc aaacgagaac acgagatgta gcaaaaaaat
     8401 tagactttga ctttggagat tttgttgatt ccgcaaatat gaaagctagt aaagattttg
     8461 gcaatgattt tatcggaatt gtgaccggac aaagaacgcc tagaatatat aaaaatagaa
     8521 acaaatatgg attactacct tttagaggtc gagatattaa aatccataaa gatgataagt
     8581 tttatattta tttacctaaa ggctttaggt ttaaagtgaa tttaggtagc aagccaagaa
     8641 aagcaagaga tgttgcttca gttttacaac acattatgga tggcgattac aaattaaatc
     8701 aaagtaatct tatttttgat ggaagaaaat tattttttaa tctaacaatt tcttttgaaa
     8761 aaagctataa tgaaatggaa ttcaagaaag gtaatgaatt gatcgtaaac tttgcagatt
     8821 tgtgtagcgg tgaatgttta attaatgata aatctgtaat gtcttttggt gatagccaat
     8881 atataagaaa cttcaaaagt aaaattttag caatgaaatc aaaagaacaa agccgaggag
     8941 tcttttctaa gggcggtcat ggtcgaaaaa gaaaattaga tcaagatcga tgggaagcaa
     9001 taaagaaaag agaaagtaat tttgttaaaa cttataataa tcaatgttct gcaaaaatcg
     9061 ttaaaactgc tattcgcaat aaagctcaaa ttattcgtat cattgaacca gataaggctt
     9121 atggcgaatg ggcttactat caattgaaag aacaactagt aaacaaagga aaaagatatg
     9181 ggatagaagt cagaagttag taaattaaac aatcgttgat ttggcaacga aatagtgagg
     9241 gaaaatccac tcactgaagg gtaaactccg tcaagttgtg tgaccagacg gaaggacgaa
     9301 tgttgttgag gttttagaac catataaaac agcatgtttc tcaaattttt aggataaggg
     9361 aaattgctag cagtttgttt tagaaccata taaaacagca tgtttctcaa atgagtactt
     9421 taaattaatt gatggcgttc ctgctttaga accatataaa acaacatgga tttaaaacaa
     9481 gaagtaagtc agttctcctt ttactttagt aaggaaaaat aaagtattct caataaaact
     9541 taaaataagc aaacctttgt tttaatagct aatcgaagta aaacccaaag ccatatgaac
     9601 ccctgaatca gcgaaagttt atgatgattt ggattactaa tagtttagga attagatggt
     9661 aaatctaaat taaacaatcg ttgatttggc aacgaaatag tgagggaaaa tccactcact
     9721 gaagggtaaa ctccgtcaag ttatgtgacc agacggaagg acgaatgttg ttgaggtttt
     9781 agaaccatat aaaacagcat agttctcaaa ttgtttaaaa tgattgtcaa gttaaaaaaa
     9841 tctgggatca tataaaatag tatagttctc aaatatgatt agaaacccta ttaaagagca
     9901 atattaagcc aacttactta aatcgtttaa ttaagaacaa taatctcttt tagtcagact
     9961 tttagtctga cttttttgta tttccaaaat ttattcttta caaaaacgaa catacgtttg
    10021 tataattgct tgtgaatggg ggaataaaaa tgtttgatta cagtagagaa ccggtgaatg
    10081 actatttttt aatcgacatg aagtctttct atgctagcgt ggaatgtatt gaacgaaatt
    10141 tagacccaat gactacaccg ttaattgtca tgagtagatc ggacaacact ggttcaggtc
    10201 tgactctagc ttcttcacct actgcaaaga aaaaatatca tattactaat gttagtagag
    10261 ctactgattt accttatcca ttaccaaaag aacttcatat tgttccacca cgaatgaact
    10321 tatatataaa aaaaaatatg gaagttaatc agatttttag aaagtatgtc gcagatgaag
    10381 atttattgat ttattcgatt gatgaatcaa ttttaaaagt gacaaaatcc ttaaatttat
    10441 ttactatata aattgagtta aattgtattc gtttttcctc ctataggcgt atactaaaga
    10501 aaacacttga ggagtgggga acatggaaac agaacgccaa atccgtgaat tggaaaaagc
    10561 gatgaatacg acagacaacc gccggttgta cgagcgtttc ctggcagtca agttggttct
    10621 tgaaggccac acccggaaag aagccgggca caccatcggc cgcgacgagc atactgtcag
    10681 ccactatgtg aaaaactact gccataatgg aatccaaggt ttagtctcca aaaaacaaag
    10741 cggacgacct tcacggctga cagatgaaca ggaagcggaa ctggtccaaa tcgtcgccta
    10801 ccacactccg gaggaagtag gtttcaaatc ccgtgccaat tggacattgg cgattgtgtg
    10861 tgacctgatt ctccgggaat ggagttatgg atatacgcaa aaaggcgtgg cggacctcct
    10921 tcaccggcta ggactaagct ggacccgtcc gacgtatacc ctcaaaaaag cggattccaa
    10981 gaaacaacag gtatttttgg aagaaacctt cccgagccta aaaaaaaatt gctgaatagc
    11041 gatattgacc acctcctatt cgaggacgaa accatgatcc gggattacca agccattggc
    11101 tgcacctggt ttctccgcgg ccaccagcga aaaatcccca cttatggaca acacaaaggg
    11161 gtaaaattga taggcacctt ggattatgaa accggtcgga tcatttgtac agaagaaggg
    11221 gcatacgacg cagcggcctt cctccgtttt ctggagcgga cgttgcggga ataccccacc
    11281 ggaaaaatcg tgatggtatt ggataatgcc cttatccacc acgccaagct gatccagtct
    11341 tttcttgaag aaaacgctag gcgcctggca ctcatcttcc tccctcccta cagccctcag
    11401 ttgaacctaa tggaaggcgt ttggaagtgg ctcaaggaat cggtcatcaa caatgttttt
    11461 tttgaccacg tccagaaaat caaacagtcg gtccgcggtt tcttagccga tgtaaacgag
    11521 cgtccccttg aggtgattga ccgactgtgc gtgcggatgt aaagtattta attcaaccta
    11581 tatagttcag gaacaagaag cgagagaaga agagaattag ctaaaataat caaagatgag
    11641 attcagaaag aaacaggtct aatagcaaca gtcggaatag gagataaccc attattagct
    11701 aaacttgcac tggacaatga agcgaagagt agtaaagaat ttatagctga gtggacttat
    11761 gagactgtac ctgaaaaaat atggaaaata aacgagatga ctgacttttg gggcattgga
    11821 tcacgcatga aaaaaagatt gaatcatatg ggaattatga gtatagaaga tttagcaaat
    11881 tggaatccct acacaattaa aagtcagtta ggtgtaatcg gactccagtt atatttccat
    11941 accaatggaa ttgatcgtac ggatattgct attccaccag aaccaaccaa agaaaagtct
    12001 tatgggaatt cacaagttct accaaaagat tatacgagga gagaagaagt agaactagta
    12061 gtcaaggaga tggcagagca agtagccatt cgaattagac aacacaattg caaaactggt
    12121 tgtgtacgct tagcaattgg tacgtcaatt ttggaagaaa aatcaggttt ctcgcaccag
    12181 atgaaaatac caattacaga taatacgaaa gaattacaaa attattgtct ttttttattc
    12241 aataagtttt atgaggggca ggaagtacga catataggag taacttatag cagattagta
    12301 tacacagatt ccctacaatt agatttattt agtgatccaa gaaaaaagat tgctgaagaa
    12361 aatttggata ggattattga taagattaga caaaaatatg gatttacagc tattatacat
    12421 gcttcatcta tgttagaagg tgcaagaagt attacgagaa gcactttaat aggaggacac
    12481 gcaggaggat taggaggttt gcataatgat tgaatataac gatagaggac gtttaaaatg
    12541 gtcgggattt tatttgtctg atcatactga aagaatcaat gcagacaatg tacaacgtgc
    12601 taatcataat ttggcaaaag aacaaatgac gactgaagag attgcgaaaa tactgagaac
    12661 tgctgtcata aaaaatagac ccgtctgcat tcaaaaagag gaacgaaacg ctgaaggtta
    12721 ctatccagat gatgtagtag gaaaaattat tggatatgac gagcttggtg tatttgtgga
    12781 agaagaaaaa gttcactatg atgaaattag gaatgtttct ttctcggaat tattaaaatg
    12841 gagtcagata tgaacattat taaaaaatac gaattcggtt atattacgta tgaacagcta
    12901 atagaggaat tatggggata tggtcaacaa ttaattaatg aagtggggat tgattgcttt
    12961 tgtttctata ttgaatccgg agcaggatac cataagaaca gatactatat atttccatat
    13021 ccaccaaaat agtctcttag atatttttaa attttctcca aatactttca attattgtga
    13081 aatatttcc
//
LOCUS       DBBGRF010000074        12743 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000074 DBBGRF010000000
VERSION     DBBGRF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.074"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACIZD4_002566"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACIZD4_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGC5991433.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="ACIZD4_002567"
     CDS             complement(323..892)
                     /locus_tag="ACIZD4_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGC5991434.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="ACIZD4_002568"
     CDS             1078..1980
                     /locus_tag="ACIZD4_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HGC5991435.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACIZD4_002569"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACIZD4_002569"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGC5991436.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACIZD4_002570"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACIZD4_002570"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGC5991437.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8323)
                     /gene="dnaE"
                     /locus_tag="ACIZD4_002571"
     CDS             complement(5003..8323)
                     /gene="dnaE"
                     /locus_tag="ACIZD4_002571"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGC5991438.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSK
                     SIKGQLIYLLGEDNVVFK"
     gene            8554..8739
                     /locus_tag="ACIZD4_002572"
     CDS             8554..8739
                     /locus_tag="ACIZD4_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HGC5991439.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8801..9997)
                     /locus_tag="ACIZD4_002573"
     CDS             complement(8801..9997)
                     /locus_tag="ACIZD4_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGC5991440.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10167..11603)
                     /locus_tag="ACIZD4_002574"
     CDS             complement(10167..11603)
                     /locus_tag="ACIZD4_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGC5991441.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11896..12705
                     /locus_tag="ACIZD4_002575"
     CDS             11896..12705
                     /locus_tag="ACIZD4_002575"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC5991442.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3804 a         2675 c         2250 g         4014 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttactcttgc tgtcatccac ccaataagca tctgacagaa
     5101 ctacttttcg ttgcgttttt tcgtgataca taactactgg tatatatcct gggtgtttct
     5161 gaaaaatcac ttgtaattgt ttcattatct cgggatcttc ccgttcttct gtaatacgca
     5221 aatagcaagt ttgtgaagga tactgggctt ctaactggtt aggatcagca aagctttctc
     5281 caattagttg cagttcctga ttatatttgc tgatttcgct ccgcccttga acaaagatca
     5341 ctcgatcaac ggcaaacaaa ttacgatatt tacgataaag agttggaaaa actgtgacag
     5401 aaatttctcc actactgtcg gttccttcaa caaaggccat cagttctcct ttttttgtcc
     5461 gaatttctct aacttccttg atcatcacta ataaattgac tggttgatta gggacgatat
     5521 ctgtaatcag ctgaacttgt ttagctaaac gaagacgatc aaacccttct gcaggatgac
     5581 ctgacaaata aatacctaag tactcctctt ccagcttcaa gcgttcttct agtgtatagt
     5641 cagcgacttc ttcttctttt aatgccatga ttcccagcaa gtcaagactt ccaccactgt
     5701 aaacgatatt ttggattttt ccttcgagat caagcatcaa ttgtttcctg ttaggagata
     5761 attcatcaaa aactcctact gctgtcagtg attgcagtaa ctctaatttc agccaacgct
     5821 tatcgatccg tatgaggaat tgatccactg actggaacgg gccattttgt tttctttcgt
     5881 ttaatatatc ttctacaaaa tcacgccgaa taccttttat cgctgtcagt ccgaatctga
     5941 tttcttcctt attgaccaac tcaaaactgg aattactttg attaatggac ggcgaggaaa
     6001 gtttgagttt atttttacgt gcttctgcaa tatattcttt caattttgat gtgttatgcc
     6061 gaacagaatt catcaggctg gtaaagaaag cacctggatg atgggctttt agatacgcca
     6121 tttggaatcc cacgaatgaa taagcaaatg catgtgaccg attgaatcca tagtttgcaa
     6181 atttttcgat atattcatat acggtcgctg ctgttttttc cgaatatccc tgttgtaatg
     6241 ctcctgatac aaaatgcgac ttttcttcat ctaatacgtc ttttttcttt ttactcactg
     6301 cccgtcgcag aatatctgac tgccctaatg taaatccagc catagtcgag gcgatctgca
     6361 tgatttgttc ctgatagacg atcactccat atgtgttttt caaaatcggg atcagtgaat
     6421 catctgggta gcgaatggct tcttttcctt tcttcctggc aatgaaggta tctatatttt
     6481 gcatagggcc tggtcgatac aatgcattga ctgcggcaat atcttcgatg ttttctggat
     6541 ctaatcttcg taaaacgttc cggataccag cagattcaaa ttgaaatact cctgaggttt
     6601 cgcctcgttg aaacaagagc agcgtttttg catcatttag cgggatctct tttaatcgga
     6661 tctcataccc ttctactcgc ttaacagctt tcaaagtaaa atcaataatc gataagttgc
     6721 gtagtcctaa aaagtccatt ttcaaaagac cgattgcttc tacctcattc atcgtatact
     6781 gggtcagaaa agcttcatca gaaccgcgtt ggagcggaac tagttcaagt agattcttat
     6841 cgctgataac tacacctgct gcgtgagtcg aaacatgtct tggcaatcct tctaaaatca
     6901 ctgcagtttt gaataaaagt tggttttttt cgcttgcctg aactaattct actaattgat
     6961 gcgaagtttt ataagcttgg gtcaatgtga ttttcaattg attgggtatt gcttttgacc
     7021 agcggtttgc ttcactttgc gataaaccaa acactctagc tgcatctcta agaaccattt
     7081 ttgctgccat tgtgccaaat gttgcgattt gtgccatatg atattgtcca tacttttctc
     7141 gaacataatt caatacttct tcacgtcgat tgtcaggaat atccaaatcg atatctggca
     7201 tcgtaaagcg ttcggggttt aaaaagcgtt cgaacagcaa atcatattct aatggatcca
     7261 catctgtgat ttctaacaca taggctacta atgaacccgc agcagaacca cgacctgcac
     7321 cggtaacgat tttgtttcta tgagcaaaag ccattacatc ccatacgatc aagaaataat
     7381 catcgaatcc catttgatgg atgacagata actcgtagtc caaacgttct tggtattcct
     7441 ttgtatagtc agtgattcgg cgttccactt gcgaatagca taactctctt aaatattctc
     7501 cagcttgttt tccattagga actggataat gcggaagtaa tttctgatgg aactggaatt
     7561 caaatgaaat cgattcagct aaacgctggg cgcctattac agcttgggaa agacccgctt
     7621 tttcgaatcg tttgatcatt tcttgttctg aaagaagata gacatttgct gttagtggta
     7681 aagatgcaga taaattttct aaaggtattt ggcttccctc tttgatatgt ttcatcactt
     7741 caagtgcaaa aagttcttct tgttgtaaac tagcgatggg atgtaatgca caaagcgaat
     7801 aattttcttt tatcacatac tgataccatt caggcaattg atcaggcgtg ttttctgtca
     7861 agccgatata aaaatttcta gtaaaaacat tttcaagtaa aaactgccaa tgaccgaaaa
     7921 agttatcctc tttattgaaa gcctcagaaa cagaatgatt tgccggaaca acaaacgcta
     7981 gatggtcggt ttctgtcatt tctgcaagtt ccaatttttc ttggatcatt tttcggctgg
     8041 aaagtttcat cagctgctga taacctattt catcttttgc gtacgcaagc aagccataat
     8101 ttttttcttc ataagtataa ctaagatgta atccaatgat tggctgtact ccttcttcta
     8161 cacaaatacg atagaattca ggtgcaccgt ataagacatc tttatccgtt atggctaatg
     8221 aagtgtagcc ttgttttttt gcttcttgta catattctcg aatacgtatc gtactttgta
     8281 aaagagaata agaagtaatt gtataaagtt gtgggaaaaa catcttgcat tccgcctttt
     8341 ttttcgttaa aattcactag cgttaaaagg tttgatcctt ttactttcat taagatagca
     8401 ggcgctgaag ttgattattc cacttcattt gcttgcttgt aatctgtagg aatgagttct
     8461 ttcgcaagaa ctcaaatttt attgagattt ggtctcgttt ctttacattc aaagaaaatc
     8521 tggtaaaatt aagatagaaa agaggtgttc tttatgcgat atatcgttac attattctgg
     8581 gctgtcgttc taggtcaagt agtcggttat attggtgctg cattaacaag cggaacatat
     8641 gattttactt tgacaacaat catttcattc attgcgggtg tcattatcct tttgattggt
     8701 gcagttgcgc caagaaaaga aacctctgcc cattcgtaaa aaaacagcca agagcttgag
     8761 atttctcaag ctctttttta ttttctactc ctcaccacca ttataatctg ctgcgaagaa
     8821 ctttacgaaa gttgaataaa gaaagaagaa tatttgacag aacaaacaaa cttgtcacaa
     8881 taaaaacagc actgtaatta taagcatgcg cgactgtcga tcctagcatg ggacctaaaa
     8941 cttgtccaaa gttgctaaac atctgattgt agctatagat tcggctgact ccttcttgag
     9001 gcgtaatctt actgatcagt gtattgacag aaggcatcaa agcgccagtt gaaaagccta
     9061 aaataaagcg aagtatacct aattggagcg gtgtagtgac gaatgccata ggtaaataac
     9121 agcaaaatga taaaatgagt cctccaatta gaactttttg attcccaatc ttatccccta
     9181 gttttcctag tttcggtgaa gaaaagacag cggaaacacc agctatcgaa acaatcaagc
     9241 cgctgacaaa aaggatattt tctgtacttc cgctcaattc acgaatatat aaggtcaaaa
     9301 tagggctgat cgtagtgatt cctatctgta aaatcaaggt cgtaatgaag agaccgatca
     9361 aaatagagag atgatccatt tttgaaaaaa tttctttggt gcttatcaga tcttttttct
     9421 cgattggatg gaaatcttct ttgactaaga aaatggtcaa taccgttgtg atcatcaaca
     9481 aagcccctgt gatcaagaat acattttcca taccaaacca ctgagccagt gcaccgccca
     9541 ttgaaggtcc gatcagattt ccagcaatcg ctccggtaga caatgttcct aacgcccatc
     9601 cgctcttttc tctaggtgcc tgtgaagcaa tcatcgctgt ggcatttgga atatatccag
     9661 acaaaatccc attccaaaac cgcatgatca aaagccaata cgcgtttggt acaaaagcca
     9721 aagatcccat tgttaatgtc atccctgctg ctgcacggat catcatgagt tttcggcctt
     9781 ttcgatcagc tagatttccc cagattggtg caaccacggc agatgcaaaa gcagtcacag
     9841 agattgctag tcccgaaaac aattcgattt gatcttttgg tgttcctagt tgctcaacat
     9901 aaactggtat gaatggcata actaaactaa tacttgcacc agtgaaaaaa cagccaatcc
     9961 acgcaatcac taaatttttt ctccaattaa tctccatcta tcatccctct ttcgtctctt
    10021 ttatcatacc tattttcgaa taaacaagca acgatctcgc cagtaaaaag agaaaaatcc
    10081 cgcaaaggtc attttatatg taacgttctt tttatgtaaa acaaaaagag atcagaacaa
    10141 atactgttcc aatcccttct ctttagttaa attgttgcta gaatgatgaa gttgataatg
    10201 aataaaatat caacgatcca caaagcaaca gaaacttgat tgtattttcc tttgattact
    10261 ttcacaattg tatagaaaat aaatcctgct gcaatcccat aggaaatgct atagcacaat
    10321 cccataaaga tcgatgcaaa gaaggccggt aaagcttctt ccatatctag ccatttgatg
    10381 tctgcaaaag aagccatcat cattactcca actaaaatca atgctggcgc agttgcttga
    10441 tttggtacaa tggcgatcag tggagagaat aaactactta atgcgaatag cactgccact
    10501 actactgaag tcaaaccagt acgtccaccg gccccgatcc cagctgcaga ttcgacataa
    10561 gttgttgtat tcgatgtacc aaagatagcc cccacagaag tagcgatcgc atcggcaaat
    10621 agtgctttat ccatttttgt tttgaaccca cgaccatctt ccaacgcgat ctcgtcttct
    10681 tttgagaaaa tacctgtgcg gcgtcctgta ccgataaatg ttccgatcgt atcgaaagta
    10741 tcagataaac tgaatgcgat gatcgtcatc aatacttgag gaatcttgga agaatcactg
    10801 aataaagatt gcatgccttc agaaccaaat gctgcaccga aagttgttcc taattcttta
    10861 aatgaattac ctaacgaatt cgtttgccaa tcaatggaac ttaaatcaac aacacccata
    10921 aaaataccaa ggactgtggt cgctacgata ccgataagaa tagccccacg gacatttttt
    10981 acaactaaaa tggctgtcag taccaaacca atcacagcca ataagatagg agcgttgtca
    11041 aagttggcta acgcagggac gattccacca tttatcgtaa catttgtcgc ttttccgcct
    11101 tcaacgacag agctcgaaat agctgactgg tctgctgaaa aagataagaa tcctgcattt
    11161 ttgattccga catacgcaac gaaaataccg atcccgccac caatcgcatg ttgaagactt
    11221 tcgggaatcg cccgaataat catttttcga atatttgtga cagtaataaa aatattgatt
    11281 aatccgcaaa taaacaccat tgccaaggct tgttgccaag aataaccaag cccaaaaacg
    11341 accgtaaaag tgaaaaatgc gttcaatccc ataccaggtg cctgagcata tggtacattt
    11401 gcgaacaatc ccattaccag cgtaccaata atcgatgcaa tgattgtcgc tagaaatact
    11461 gcttggaagg gcatacctga tgctgacaaa atcgtcggat ttacgaataa gatataactc
    11521 atggcaaaga atgtcgttac tcccgccatt atttcagttg atacatttgt attgtttttc
    11581 tttaaaccga aaaacttttc cataaaaagt tccactccct gaattttttt ctgatggaaa
    11641 actataataa taaaaaataa gtaaaatagg gcaaatccat cgaacaattt caaattatat
    11701 agacgtttca ttcgcttttc aacgtttttt taacaaaaaa agcgaaaata atacttaacg
    11761 ttcgtgttta gcttatgttt agctatttat atagccataa ctgtagtttt tgttaggaat
    11821 agctgattgc tcttgttaat tacctaaaat atgctagact aaaacaaatg ctagttgagg
    11881 aaggaaggac ccttattgaa taaaaaatta attgccatcg atctggacgg aactaccctc
    11941 aatcaagatt cgatgattac atctaaaaca aaagagactc taaaaaaagc aatcaatgcc
    12001 ggtcatcatg tcagtattgc tacaggacgc ccattccgaa tgagccatca gttttaccaa
    12061 caattagaat taacaacacc gatggttaat tttaacggcg cattagtaca catccctaat
    12121 cagcactggg atggtgaaag agaaacgttg atcaatcgtg aaatcgcttt tgaaatctta
    12181 tcgcaaaaaa agcagctaaa tttagatttt atcgctgctg aaaatcgtga tacttttttt
    12241 attgacagtt ttgatttctt tgatgaaaaa atttttgctt cttctcgtcc aggagagaag
    12301 aatttgcttt ctcctaaaaa tttgacgaca aatcctacat ctttgcttgt ccgaacagac
    12361 aaacgttttg caggagctgt atctgctgaa ttaacacgtc aatttggcag ttatgtcgat
    12421 gttcggacat ggggtggacc tactgccatc ttagagattg tttcaaaagg aatccaaaaa
    12481 gcaaaaggcg tgcaagagat tgctaactac ctgtctatcg atcaaaaaga cgtcattgcc
    12541 tttggtgacg agcataatga tttggaattg ttggattatg caggttgggg agtagctatg
    12601 gctaacggta ctgaccaact caaaggcatt gcaaatgatg tcactccttt gagcaatcag
    12661 gaagacggtt tagctgttta tctggaaaaa ctacttaaac tataatagag aattagattc
    12721 cacaaaaaag aggttgtgac aat
//
LOCUS       DBBGRF010000075        12670 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000075 DBBGRF010000000
VERSION     DBBGRF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.075"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            6..305
                     /locus_tag="ACIZD4_002576"
     CDS             6..305
                     /locus_tag="ACIZD4_002576"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC5991443.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACIZD4_002577"
     CDS             378..1739
                     /locus_tag="ACIZD4_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HGC5991444.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACIZD4_002578"
     CDS             1761..2021
                     /locus_tag="ACIZD4_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991445.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACIZD4_002579"
     CDS             2035..2787
                     /locus_tag="ACIZD4_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HGC5991446.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACIZD4_002580"
     CDS             complement(2881..3486)
                     /locus_tag="ACIZD4_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGC5991447.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACIZD4_002581"
     CDS             complement(3539..4513)
                     /locus_tag="ACIZD4_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HGC5991448.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACIZD4_002582"
     CDS             complement(4891..5610)
                     /locus_tag="ACIZD4_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGC5991449.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACIZD4_002583"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACIZD4_002583"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGC5991450.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACIZD4_002584"
     CDS             7161..8558
                     /locus_tag="ACIZD4_002584"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC5991451.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACIZD4_002585"
     CDS             8639..9079
                     /locus_tag="ACIZD4_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC5991452.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACIZD4_002586"
     CDS             9227..9553
                     /locus_tag="ACIZD4_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC5991453.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACIZD4_002587"
     CDS             9554..10303
                     /locus_tag="ACIZD4_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HGC5991454.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACIZD4_002588"
     CDS             complement(10383..10838)
                     /locus_tag="ACIZD4_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGC5991455.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="ACIZD4_002589"
     CDS             complement(11265..11540)
                     /locus_tag="ACIZD4_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991456.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="ACIZD4_002590"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="ACIZD4_002590"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGC5991457.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         4055 a         2175 c         2587 g         3853 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag
//
LOCUS       DBBGRF010000076        12635 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000076 DBBGRF010000000
VERSION     DBBGRF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.076"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(146..1111)
                     /locus_tag="ACIZD4_002591"
     CDS             complement(146..1111)
                     /locus_tag="ACIZD4_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGC5991458.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            1345..2190
                     /locus_tag="ACIZD4_002592"
     CDS             1345..2190
                     /locus_tag="ACIZD4_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGC5991459.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            2381..3568
                     /locus_tag="ACIZD4_002593"
     CDS             2381..3568
                     /locus_tag="ACIZD4_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGC5991460.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            3574..3930
                     /locus_tag="ACIZD4_002594"
     CDS             3574..3930
                     /locus_tag="ACIZD4_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGC5991461.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            3932..4270
                     /locus_tag="ACIZD4_002595"
     CDS             3932..4270
                     /locus_tag="ACIZD4_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HGC5991462.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    4346..4602
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4665..5699
                     /locus_tag="ACIZD4_002596"
     CDS             4665..5699
                     /locus_tag="ACIZD4_002596"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGC5991463.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            5692..6378
                     /locus_tag="ACIZD4_002597"
     CDS             5692..6378
                     /locus_tag="ACIZD4_002597"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGC5991464.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            6402..7250
                     /locus_tag="ACIZD4_002598"
     CDS             6402..7250
                     /locus_tag="ACIZD4_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC5991465.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            7447..8220
                     /gene="sufC"
                     /locus_tag="ACIZD4_002599"
     CDS             7447..8220
                     /gene="sufC"
                     /locus_tag="ACIZD4_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGC5991466.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            8233..9519
                     /gene="sufD"
                     /locus_tag="ACIZD4_002600"
     CDS             8233..9519
                     /gene="sufD"
                     /locus_tag="ACIZD4_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGC5991467.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            9516..10751
                     /locus_tag="ACIZD4_002601"
     CDS             9516..10751
                     /locus_tag="ACIZD4_002601"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGC5991468.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            10738..11208
                     /gene="sufU"
                     /locus_tag="ACIZD4_002602"
     CDS             10738..11208
                     /gene="sufU"
                     /locus_tag="ACIZD4_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGC5991469.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            11213..12604
                     /gene="sufB"
                     /locus_tag="ACIZD4_002603"
     CDS             11213..12604
                     /gene="sufB"
                     /locus_tag="ACIZD4_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGC5991470.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
BASE COUNT         4179 a         2366 c         2798 g         3292 t
ORIGIN      
        1 ttacgacctc ttggtaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccag
       61 tacaaaaaca tgaacagctg tttttgtttg gccgttctta ttacttgatg cagaacagct
      121 ttttcacaac ctattgaatc gattattaag cgattttttt agaaacaaat tttccatgtt
      181 tgctatgttc tttaattaag aaacgtacgt aatgagcaag aacgtagaag acaactacac
      241 ttgcaaacag acattccgca acttttaaga aatccaatac gctactatag atacctaaac
      301 tgttgaagta atgaacagta gtaaatatag ctgttgcaga gataacaagc gggaatgtaa
      361 aggctgcata gcttggataa aaacgaagct tgaacaaacg tggaagcata gacagcacaa
      421 cgaaatacaa tacttgagat aaagcgaaca atgctacgac aagataaaaa ttaggttcag
      481 caaagttttt aagataacct gttaggcaaa gagaaccagg tgctgcaacg atcgtaatca
      541 gcggacgtgt cggatgagcc atatttctta cgaaaaagac acgtttgatg atgatcggca
      601 ataagaacgc atagcagatc aatgaaatcc aaaagaaaat ttttccaata agtgggaaga
      661 agttcccggc agttacagtg atgaccccaa atccaacgta aatgataaac cagcttggat
      721 aaattgcttc aattgaaaga tcagctttga taacatggtg ataattgaaa taaaagacaa
      781 ggatcacttg gaagataaca gcgcacagcc aaatgaattt gacaattggt gcaatacttt
      841 catatgaaac aaaataagta caaataacca tgagtgacat cgtaaaagtt ggtgaaacgg
      901 aggcgatgat tggatcatgc aacgtttgtt tcgtgtgttc gaataagata aacaatttaa
      961 caaaaatgaa tatcataaga atcatagaga taccgccagt tagattgcct aaagcaacat
     1021 ggtgatagtc tttaaacaga tttccaaggg aagctaaccc aaggatcaac ccgcagatcg
     1081 ggatcggaat aattttcaaa aagttcttca tatataatat tctccttttt atttaataga
     1141 ttttagtacc aagatgaacg aatacattgt aaaatgaata ggaatgtatg attacgagca
     1201 agcagacagc tgattgtctt catctaagtt actagttgga tcagcaactg ttttgttgta
     1261 catttctatt atagatggtt ttttgtatat ttaaatcaaa tagtttttat agtaattatc
     1321 ataaaaagtt atggaagtgg tgccatgttt aagttattaa cgacttttcg agcagtatat
     1381 gaaacaagaa atttttccag agcagcagaa gtactgtttt tatctcaacc agcagtctcg
     1441 aatcaaatca aacagttgga gcgggaattg aatatcgatc tttttcaacg taacggaaga
     1501 aaagagatgc ttccaactaa gcaagccgac ttattatatg aacggacact ggttttgtta
     1561 gaagaatggg aagaaactca gcaaaaattg ctcaatgaac aaaatgaaga agaagtatgt
     1621 cggatcgttg cttcccacac ctttgctgtc tatcttttgc ctcagttgat gaaacatctg
     1681 atcaaaaggt ttcctaaagt gcattttgag atcgaaatca cgaattctca tgaatcatta
     1741 gaacaagtag cgaaacatga atccgatttt ggttttatcg aaaagccatt agagacttcc
     1801 ggcgtacaaa gatactcttt gatggaagac cagctagtca tcgctgggga cccaaaaagc
     1861 aaattgtggc ttgtaagaga agcaaactct ggtgtttttc attacacgca gcgttatttt
     1921 gaagagatga atatccaaga taagaagatg atcgtgaaaa gtaacgatgt aattgttgcg
     1981 ttgctgaagg aaggaatcgg tcgctcgatt ttgtctaagc gctctgttcc agaaaatgtg
     2041 ccaatgactc cgttgaattt ccatcgatat ttttatttca tccaacgaac caatctggtt
     2101 tctgatcagc tgctagagat tgccgaagag atccttcgat acaatgaaag cacagaaact
     2161 tctcacagcg aggagaatct cagctggtag ataattgcat gtatcaaaaa aagttctatg
     2221 atacactaaa gataagcagt aggcttttgt actgcatttg ctcaagcaac tgcacaaacg
     2281 gaaagttaat ttttcccaaa tgtctatgga aagactttcc attatctaac tggaccgcta
     2341 taataatcag cagtatggtt tttaagaaaa gggatgaaac atggaaaaaa aattaaaagc
     2401 ttcgaacgat aatcgtattg attatggcgt gattttacca gtctttctgt tatgtttgat
     2461 tggtctgctc tcattatatg tagcacttag ccatgatccg aacaatccag cagtcttgaa
     2521 aggcgtaggg atgcaagttg tctggtattt agttggagcg gcagcaatcg ttgtcatcat
     2581 gcatttgaat tccaaatgga tctggaaact gactccttac ctttatggtt tggggttagt
     2641 ggtaatggga ctcttgctca aattctatga tcagaattta gctgcttcaa cagggtctaa
     2701 aaactggttt cgattcggtg cgtttacttt ccagccagca gagttgatga agattgcgta
     2761 catcttgatg atggcactga tcgtaactaa acataatacg caagtaaaag aacggacgat
     2821 gaaatcggac ttttggctga ttgggaagct cttgatcgtg acaataccgg ttttagcatt
     2881 gatcatggcc caagatgact ttggaacgat gcttgtcttt cttgcgatct ttggcgggat
     2941 tttcctgatg tctggaatct cttggcgcat catcgcacct gtagtaatct tggcagtagt
     3001 cgttggagca ggaacgatct tcttggttac gactgaaggc ggaagagact tgctttataa
     3061 agttggattc aaatcttatc agtttgcacg tattgattca tggctggacc ctttccatga
     3121 tacgtcagga atgagttatc agccggccca aggacttttg gcaattggta ccggtggctt
     3181 gtttggtaaa ggattcaacg taagcaatat ctatgtgcct gttcgtgagt ccgatatgat
     3241 ttttaccgtt atcggtgaaa acttcggctt tatcggtggt gcattcgtca ttttcttgta
     3301 ttttatttta atctatcgta tgattcgggt gtgtttcgat acgaataatg aattttacgc
     3361 ctatatcgca agcggtttga tcatgatgct gctgttccat gtctttgaga atattggagc
     3421 aaatatcgga ttacttcctt taacagggat cccattgcct ttcattagtc agggaggatc
     3481 ctcgatttta gggaacatga tcggtatcgg gttgatatta tcgatgagat accaaaatga
     3541 agcacctgca agatcttcaa ggaggtaaga aaattgtaca ccttttactg gtacccgaaa
     3601 tgttcaacat gcaaaaaagc caaagcgtgg ttagaccagc atggcgttag ttatcaaacc
     3661 gttgatatga tcaaagaagt accgaaggcc tcaacgattg agacttggct agaaacgagt
     3721 caagtaccaa tccgtcgcct gttcaacaca agcgggatga aatatcggga acttggactg
     3781 aaagatcaag taggcgagtt tacggcttca aaagcgagcc aagtcttatc gacagatggt
     3841 atgctgatca agcgaccact gatcttacga gaggaccagc ttgttgcaat tggattcaat
     3901 gaaaaaattt atgaaggaga actgatataa aatggcaggc aagcatttga agaaaaagga
     3961 caacctttgg atcttattta atggaaaaga atactgtgtt ggtttgacaa atgaagcgca
     4021 agaagaactt ggagacatca cgtttgccaa tctgccaaaa gcaggacaat cgctaaaaaa
     4081 agatgaacct ctgatcgaag ttgaagcgga aaaagcggtc aatgaatttg ccagcccgct
     4141 aacgggtaca gtttcttctg ttaatgataa aatcggtgaa gatatcaata tcttgaatga
     4201 ttcagatgaa atgaatgcgt ggatcttaag tttcaaagat gttgatccaa aagaatttga
     4261 cgaattataa aatcagaaaa tcacttgaaa aaagttgaca ctgattcttc cagttgctat
     4321 aatcataagc aatcctatat gaaacgagaa agctttgaaa agaagagtac atgtcacgga
     4381 cgtttgaaga gagccctgtt tgctgaaaat gggtaacgaa aatgagatgg aagatggtct
     4441 tagagcagag taagcgagcg taagcaaact tactacggga gtgcccgtta cagcgcgaca
     4501 gtatacggaa agaagctaag tccaagtact ggaagaggct gttattgcga agtaacggta
     4561 aatcaaggtg gtaacacgga agttcaagct ttcgtccttt tgcttaaggc aagagggcga
     4621 aggctttttt gtttgaaaaa ttataagaga aagatgtgaa tggcatgtca ttaatccaac
     4681 taacgaatgt caaaaagaca ttcaatggga aaaacggaaa catccaagcc gtcaatgacg
     4741 tttcactaaa cgttgaaaaa ggggatattt atggaatcgt cggctattct ggcgcaggaa
     4801 aaagtacatt agtccgtctc ctgaatggac ttgagcttcc cacgagcggc gaagtgatcg
     4861 taaacgatca agatattaca aaattaaaaa acaaagaatt acgtacattc cgaaagaaaa
     4921 tcggtatgat cttccagcat ttcaacctgt tatggtcaag aactgtactt gaaaatatcc
     4981 agctgccgct ggaattagct ggcgtaccaa agagcaaacg taaagaacgg gcagaagaac
     5041 tgttgcgttt agtcgggtta gaaggacgcg gacaagcata tccttcacaa ctttccggcg
     5101 gacagaaaca acgcgtcggt atcgcacgag cattggcaaa tgatcctgag atcctgcttt
     5161 gtgatgaggc tactagcgca ttggacccgc aaacaacaga agaagtatta gacttattgt
     5221 tagcgatcaa taagaaattg aatttgacca tcgtcttgat cacacatgaa atgaatgtga
     5281 tccgcaaaat ctgcaacaaa gtcgctgtga tggagttggg gaaagtcgta gaagaaggag
     5341 acgtattgac tgtcttcaga caaccgaaaa aagaagtaac caaacgcttt gtacaacaag
     5401 acatcgaacc agaagctgat tcgacagaac tattagctga actcatcaaa gaaaatccaa
     5461 gcggccgttt ggcaactttg acctttagcg aaagaaatgc caacgagcca gtcatttccc
     5521 aagcgattcg acgctataac atcgatgtca acgttgtgta tggaaagatc aaacaagtga
     5581 aagaaggttc ctttggttca ttgactgtct tgatgactgg tgaaaccaaa gaattagatc
     5641 aagcagaagt gttcatcaaa gaacaaggag taggaattga ggtgatccat cgtggataaa
     5701 agcttttcag aaacatatct agattttaaa caaatcaacc cggaaacgat gaatcaggct
     5761 atccttgata cactatatat gacattaatc tcaatggtct tagtgacgat catcggatta
     5821 gttttgggat tgatccttta ctctattgga cgcaaaaaca aaccgtatgc tcgaatcatt
     5881 tatggaatcg tatcgatcat cagtaatatt ttccggtcaa cgccatttat gatcctgatg
     5941 gttttgatca ttccatttac taaagcaatc gtaggcacta tgctaggtgc gcaagcagcc
     6001 attccagctc ttgttttatc cgcagcacca ttttatgccc gtctagtaga gattgctttt
     6061 cgtgaagtca gccctggtgt actggaagca gcagatgcaa tgggagcaag ttactgggaa
     6121 atcatctgga aggtcttgat acctgaaagt attcccgcat tgatttctgg attaacagtt
     6181 acaacgatct cgatgatcgg atttactgcg atggccggcg cgatcggcgc aggtggactt
     6241 ggaggtcttg cttggcagga aggctaccag cgtggtaatc taacagtgac attcgttgcg
     6301 actttaatta ttttactaat cgtatttatc gttcaaggaa tcggtgattt cttaactaag
     6361 aaaacagaca aaagataata ggatataggg ggatgtagga tatgaaaaag aaaatttttg
     6421 gatttgcagc agcgcttttg ctgactgtag gattagcagc atgcggtaac aacagcgaca
     6481 gcaaagattc agcaaataaa gcagacgaca cgacattgaa agtcggcgct tcaccgacac
     6541 cgcacgcaga gattttggaa catgtgaaac cattattgaa agatgaagga atcgatcttg
     6601 aaatcgtcaa attcgatgac tatgtattac cgaaccaatc tttggaagaa ggcgacattg
     6661 atgccaatta cttccagcat attccttatt tgaacaaaga aatcaaagaa aaaggatatg
     6721 actttgtcaa tgccggtgct gtccacatcg aaccaatggg cttgtactct aaaaaagtca
     6781 aagatgtttc cgaattaaaa gatggtgcaa caatcattac ttcaaattct gaatcagact
     6841 ggggacgcat catcacaatt ctacaagatg ctggcttagt caaagtcaaa gatggagtag
     6901 atctggaaac agcaacattc gatgatattg aagaaaaccc taagaacttg aagttcaacc
     6961 atacgatcga cccatcactt ttagcttcta cgtaccaaaa tgatgaaggt gacctagttg
     7021 caatcaacgc aaacttcgct tacggcgcag ggttgaatcc attagaagat gccgtattgc
     7081 ttgaaaagga caactctcct tacgtgaata ttattgcgac tcgtaaaggt gatgaagaca
     7141 gtgacaaaat caaaaaactg attgaagtgc ttcaccgcaa agaagtccaa gaatggatca
     7201 cagacaaatg gggcggctct gttaaaccag taaaggctga tgcaaaataa ggtatggaac
     7261 aaaaaagatg agaaataagt ctgtaatggc ttatttctca tcttttttat acctattcta
     7321 atttagaaat caaaattgtt taataataaa taaaagatat ttgattttag taaggaaggt
     7381 cattgcgctt cattctcaat tagtctaaaa tgagtgagaa cgaaagagaa tttgggggta
     7441 taatgcatgt ctgtcttaga aataaaaaat ctacatgtgt cgatcgagga aaaagaaatc
     7501 cttaaaggcg taaacctaac aatgaaaacc ggagaaatcc atgccatcat gggacctaac
     7561 ggcacaggaa aatctacctt atctgccgct atcatgggca atccaaacta tgaagtaaca
     7621 gaaggcgaaa ttttgtttga cgggaaaaat gttttagact tggaagtaga tgaacgtgcg
     7681 cgacttggct tatttttagc tatgcaatat ccaagtgaga taccaggtat cacgaatgcg
     7741 gaattcatgc gtgcagcgat caatgcgaaa cgtgatgaaa acgacaaaat ttctgttatg
     7801 gcatttttga aaaagttaga tgaaaaaatg gctttactaa atatgccaga agaaatggct
     7861 gaacgttatc tgaacgaagg tttttctggc ggagaaaaga aacggaatga gatcctgcaa
     7921 ttgttgatgt tagaacctac atttgcaatt ttagacgaaa tcgattcagg tctggatatc
     7981 gatgctttga aagtcgttgc taaaggagta aatgaaatgc gcggagacaa tttcggtgca
     8041 ttgatcatca cccactatca acgattattg aactatatca cacctgatgt cgttcacatc
     8101 atgatggaag gccgagtagt catgacaggg aatgctgacc tagctaaacg tctggaagca
     8161 gaaggctacg ctggtatcag taaagaatta ggaatcgact ataaagaaga agaagcgtaa
     8221 gggggagcaa gaatgaaaga aaaaaactgg ctcgattatc ttgacgcggt aaatgatttt
     8281 tctttaagta aaggcgaacc tgattggatg agaaccttcc gtcaagacgc actagcgaaa
     8341 gcagatgaac tgccattgcc gcatatcgat cgggtgaaat tccatcgctg gtcgttattt
     8401 gatgtgaaag aaacacaaac catcagtgaa acaggcacga ttccggcatt tgatgcaatg
     8461 aaagacaatc ctgtgcttgt ccaacaaggt tcatggacga tttttgaaca actgcctgtg
     8521 gaattagcag aaaaaggagt catttttacc gacttgttca ctgcaatgat cgaatatcca
     8581 gaactagtcc aagaatatta tatgaaaaaa gcagtaaaca tgaacgaaga ccaattgact
     8641 gcactccatg tagcttttat gaacagcggt attttcctgt atgtgcctaa aaatgtcgtg
     8701 atcgatgaac cactcgagtc cttattcatt caagatggcg catccgatga gcacttcttc
     8761 aagcatgtgt tgatcgtggc agatgaacat agtgaatttt cttatctgga acgtttccag
     8821 acaaccaaag aacaagtagc aaaatcatca ggtaatatca tcgtggaagt catcgctaaa
     8881 gctggttcaa aaatcaaata ttcagccgta gatcaattag gagaaaatat tacttcttat
     8941 atgaatcgcc gtgggcacat tttacgagat gcttctgtcg actgggcaat tggtgtcatg
     9001 aatgacggtc atgtgatcgc tgactttgac tcagatttag caggagaagg tgcacacgca
     9061 gaagtcaaaa tcgtggcaat cagctcgggc agacaaatcc aaggaatcga tacacgagta
     9121 accaataaag cccctcatac gatcgggcat attttgcaac acggagtgat ccgagaaaaa
     9181 ggaacattga cctttaatgg tatcggccac atcttgaaag gggcaaaagg tgcagatgcc
     9241 caacaagaaa gtcgtgtctt gatgctttct gataaagcac gtggtgatgc gaatcctatt
     9301 cttttgatcg atgaaaacga agtaactgct ggacatgctg ccagtgtagg acgagttgat
     9361 ccagaagaaa tgtactatct gatgagtaga ggattgcata aagaagaagc agagcgctta
     9421 gtgattcgag gattcctcgg ttctgtctta acagcaatcc ctgtagaaca agttcggaaa
     9481 gaattagtcg aagtaatcga agggaagttg aatggatgat cgatgctaaa aagctacgca
     9541 atgattttcc tatcttattt caagacgtca atgatgaacc tttagtttat ctggataatg
     9601 cagcgacgac ccaaaagcca aaacaagtac tccaggcatt agcgtactat tacgaacacg
     9661 ataacgccaa tgttcatcgc ggtgtccata cgttagcaga acgcgcgacc catgattatg
     9721 aacaagcaag agaaaaagta cgggcgttca tccatgcaaa agaaacagca gaagtgctgt
     9781 ttactcgtgg tacgacgaca agcttgaatt gggtagccag aaccttcggc gaccgctata
     9841 tcaaagcagg agacgagata gtgctctctt acatggaaca tcattctaat gttatcccgt
     9901 ggcagcagtt ggcaaaacga acaggtgctg tcttgaaata tatcgaacta acagaagaag
     9961 gcttcctgga tatggaggat gcagcgaaaa agattacgga caaaaccaaa atcgtctcca
    10021 ttgctcatgt atccaatgtc ttaggtgtct tcaatcctgt tcaagaatta gctgaacttg
    10081 tccatgaaaa cggcggggtc atcgtagtag atggtgctca atctgccccg cacatggcca
    10141 ttgatgtcca agcactagac tgtgatttct ttgctttcag cggacacaaa atgtgcggac
    10201 caacaggtat tggtgtttta tatggtaaac gaaaatggtt agaagaaatg gaacctgttg
    10261 aatttggtgg cgaaatgatc gattttgtcg aattatacga cagtacatgg aaagaactac
    10321 cttggaaatt cgaagcaggg acaccaaata tcgccggcgc tatcgcatta ggccatgcaa
    10381 tcgattattt gcaaaaactc ggtatggaca atatccatcg atatgaagaa gaactagccg
    10441 cttatgtgtt gccaaaatta caagcaattg atggattgac tgtttatggt ccacaagacc
    10501 cgaattttcg gacaggagtc gttgcattca atttggatgg gttacatccc catgatgtcg
    10561 cgacagcttt agacatggaa ggggtagccg tcagagcagg tcatcattgt gcgcaaccgc
    10621 tattgaagta ccttgaagta tcagcgactg ctcgcgcgag cttttatttc tacaacacaa
    10681 cgcaagacgc cgaccgttta gttgaagcaa tcatggcaac aaaggagttt ttccaacatg
    10741 ggactatcta aattagacaa tttataccgt caagtgatct tggatcattc ttcccatccg
    10801 catcatcgtg gaagcttgac tgactcgaca agcaagatcg aattgaacaa ccccacatgt
    10861 ggagatgtga tcgaattgca agtcgatgta aaagacggaa tcatcaaaaa tatcgccttt
    10921 gacggcagtg gctgctccat cagtacggca agtgcctcga tgatgacaga cgccgtcatc
    10981 ggaaaatcaa tagaagaagc agaacattta actgtagact ttctacagct tgtccaagga
    11041 aaagaagtca aagatcccga ccaattaggc gatgctgcta tgcttggtgg tgtagctaaa
    11101 tttcccgctc ggatcaaatg tgcgacactt gcctggaaag cactaggaaa agcaatggaa
    11161 aacgatggta ccgcagcttt ccatcattac cacaaggaag aggagtgaga acatgggcgt
    11221 accagaatta gaagaatata aattcgggtt tcacgatgat gtcgaaccgg ttttcagtac
    11281 aggagaaggc ttgacagaag aagtgatccg tgagatgtca agaatcaaag gcgaaccaga
    11341 atggatgctt gaattccgtc tgaaatctct agaaacattt aacaaaatgc caatgcaaac
    11401 atggggcccc gacctttcag acatcgattt cgatgccatc aaatattacc aaaaaccaag
    11461 tgacaaaccc gctcgtgact gggaagacgt accagaaaaa atcaaagata catttgaaaa
    11521 gattggtata ccagaagctg aacgagctta tctagccggt gcttccgcac aatatgaatc
    11581 agaagtcgtg taccataata tgaaagatga attcgaaaag ttaggaatcg tctttactga
    11641 cactgactct gctttgaaag aataccctga attattcaaa gagtactttt caaaacttgt
    11701 accgccaacc gacaacaaat tagcagcgct gaattcagcc gtatggtcag gtgggacctt
    11761 tatttacgtg ccaaaaggcg tcaaagtcga tgttccatta caaacgtact tccggatcaa
    11821 tgcggaaaac acggggcaat tcgaacgtac gctgatcatt gttgacgaag gagcaagcat
    11881 ccactatgtc gaaggttgta cggcacctac ttattcaagt aacagcctgc atgccgccat
    11941 cgtagaaatc tttacaagaa aagatgcgta ttgccgttac acaacgatcc aaaactggtc
    12001 agacaatgtg tacaacttag taaccaaacg agcaaaagca tacgaaggcg caaccgttga
    12061 atggatcgac ggaaacctag gtgcaaaaac aacgatgaaa tacccaagtg tttacttaga
    12121 tggaaaaggt gcacgaggca ccatgctctc catcgccttt gcaggagcaa accaaatcca
    12181 agatacgggt gcaaaaatga tccacaatgc accaaataca tctagctcta tcgtctctaa
    12241 atcaatttca aaagacggcg gagaagtaaa ctatcgagga caagtaacct ttgccaaaaa
    12301 cagtgcgggt tcgatctctc atatcgaatg tgacacgatc atcatggacg aatggtcgaa
    12361 atccgatacg atcccattca atgagatcca caacagccaa gtctctttag aacacgaagc
    12421 caaagtctca aaaatctcag aagaacaact ctactatctg atgagccgag gcctgaccga
    12481 atctgaagca actgaaatga tcgtcatggg ctttgttgaa ccattcacca aagaacttcc
    12541 aatggaatat gcagtcgaac tcaatcgatt gatcagttat gagatggaag gcagtgttgg
    12601 gtaaacctgt tataggagct agaacccttg atata
//
LOCUS       DBBGRF010000077        12600 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000077 DBBGRF010000000
VERSION     DBBGRF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.077"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..375
                     /locus_tag="ACIZD4_002604"
     CDS             <1..375
                     /locus_tag="ACIZD4_002604"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991471.1"
                     /translation="VKDNRNSIRKEVLHLIKFVKKTVAIPSEKKINESTRKLYRRANK
                     KALKLSAFLSSLSLKLSLILFISEHVSITDFLNLAKNPYLKGVRSILWQGLQSLACLE
                     VRTWFSYSSCRKIFLMMILSIN"
     gene            complement(324..893)
                     /locus_tag="ACIZD4_002605"
     CDS             complement(324..893)
                     /locus_tag="ACIZD4_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC5991472.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(967..2256)
                     /locus_tag="ACIZD4_002606"
     CDS             complement(967..2256)
                     /locus_tag="ACIZD4_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991473.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESENKSKLTKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQAFAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            2514..3458
                     /locus_tag="ACIZD4_002607"
     CDS             2514..3458
                     /locus_tag="ACIZD4_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5991474.1"
                     /translation="MEEKIEESKQKIDQLIQELEKAVIGKRSTIQLMIVALLAGGHVL
                     FEDIPGVGKTLLVKALAKAVQGTFSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPI
                     FTTILLADEINRTTPRTQSALLEAMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTY
                     PLPEAQLDRFLFRLQIGYPSFDDELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANV
                     FVSPEVASYALQLVSATRSHAAIQLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQD
                     LVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQIPVPVR"
     gene            3472..4545
                     /locus_tag="ACIZD4_002608"
     CDS             3472..4545
                     /locus_tag="ACIZD4_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HGC5991475.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKREISFPVTVL
                     PAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKLSAHTQEWLY
                     REYDYQEEECSPLFCFWGSHSPKFEPLLDLYFSLWHLRKEKQPELLILGNRAFHGKDP
                     GHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKDRTVYLVYFV
                     EKQLMVQEKDKICSLPGGEWIDD"
     gene            4535..6706
                     /locus_tag="ACIZD4_002609"
     CDS             4535..6706
                     /locus_tag="ACIZD4_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HGC5991476.1"
                     /translation="MTIKWEKWLCGVYSFVILSVGAPIFVVANQLQNSYLLILTIGVL
                     CLIVCCIPKKWVRLLLSLPVMIGCLFLYFPSKTFSLLWILQFFSSVTEEFFHLSQGKL
                     YYLPEKTAFFLIMLLIYLFITLTVDYDYLYAPFLSLMAYFMMLTVFREKDLLYEMIAV
                     VTVLFVYLAARQFFSMRLLSRNTRFQSLTTVLLICFLTISAILPLYLPKVHQSLEETS
                     EPIREYLNDEGLYDTLHEYQLTGSARTGFSENDEQLGGPLYDNGEVVFTANQKGNGYW
                     KIENKNHYTGSGWIEDQDAPIQPIQEFPVDITSYQTVMEDKENITLTLKKQAFLPYPY
                     GNTTLTDFSLASGQTLYYLPESQRFIPVPNESTRSATLQTERLVFTREELKSSQLKAD
                     DLENQQTNLQLPKSLPKRIEDLAVELTKNEATLIRKVEAVEQYLKTSGNFRYSKTDTG
                     HTPKEHDYVDYFLFDSKVGYCDNFSTSMVVLLRTLGIPARWTKGFTNGLRTGTDNQGN
                     EEYSILNSHAHSWPEVYFPGFGWLPFEPTPSFANPMGSQPVAETTETVQPAIEQPNES
                     ENMAETISSERSEVIPSEETTLTPAYKIVLFSLGVCLYVLLFFLLLFRKSLRWTSYLI
                     YLHFFASTNTIAYQKLLNHLETLVPRKPAESLQEYSLRIEQEFKLDLRFIRLTTQYEA
                     EIYGRQADPVNFDKKTYLEITHIIRKTVYKKVLTKGSRFKK"
     gene            complement(6818..8986)
                     /gene="copB"
                     /locus_tag="ACIZD4_002610"
     CDS             complement(6818..8986)
                     /gene="copB"
                     /locus_tag="ACIZD4_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HGC5991477.1"
                     /translation="MDHSMHMGHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHMG
                     HNHGDIANSKQMDHSMHMDHDHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGME
                     FPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYIY
                     SVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPES
                     VKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGIK
                     KQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAKW
                     LFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAAK
                     NGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGALE
                     ANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKNQQVKIVNEKEVERLGL
                     NVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVMLT
                     GDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLARA
                     SIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILAI
                     PLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9117..11303)
                     /locus_tag="ACIZD4_002611"
     CDS             complement(9117..11303)
                     /locus_tag="ACIZD4_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGC5991478.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKSKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMSSSLASIAQTIELSRVTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11303..11512)
                     /gene="copZ"
                     /locus_tag="ACIZD4_002612"
     CDS             complement(11303..11512)
                     /gene="copZ"
                     /locus_tag="ACIZD4_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HGC5991479.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(11525..11965)
                     /locus_tag="ACIZD4_002613"
     CDS             complement(11525..11965)
                     /locus_tag="ACIZD4_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGC5991480.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12039..12537)
                     /locus_tag="ACIZD4_002614"
                     /pseudo
     CDS             complement(12039..12537)
                     /locus_tag="ACIZD4_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
BASE COUNT         3538 a         2652 c         2234 g         4176 t
ORIGIN      
        1 gtcaaggaca atcggaatag catacggaaa gaagttctgc accttataaa atttgtcaaa
       61 aaaactgttg ccattccaag tgaaaaaaag atcaatgaat caactagaaa actatataga
      121 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
      181 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
      241 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
      301 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
      361 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
      421 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
      481 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
      541 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
      601 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
      661 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
      721 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
      781 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
      841 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
      901 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
      961 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     1021 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     1081 atcggtgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     1141 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     1201 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     1261 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaaatgc
     1321 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     1381 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     1441 aagccattct tggtaaagta cttttgtcag ctttgatttg ttttcgctct caaattcgct
     1501 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     1561 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     1621 tgctagataa tttttttctt ttattggcaa aatctgctct tctctaaata gcaattcagg
     1681 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     1741 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     1801 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     1861 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     1921 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     1981 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     2041 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgga tgggacagtc
     2101 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     2161 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     2221 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     2281 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     2341 tatttaaata cgcaaatttt cctcattatt tttaatttta ctcaatttaa tcgtattctc
     2401 atttcaaaac gaatgtactt taaaaaaaca taataaaatc actttgcttg taggatgtat
     2461 tcccttccat tacaatgaaa taaatagcaa ttttatgaga aggtgatgtg aaaatggaag
     2521 aaaaaatcga agaatccaaa caaaaaatcg atcagttgat acaagaatta gaaaaagcgg
     2581 tcatcggcaa acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg
     2641 tcttattcga agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag
     2701 ctgtacaggg aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc
     2761 ttggtttttc cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct
     2821 ttaccacgat cttgttggca gatgagatca atcgcacgac tcctcgtact cagtcagcac
     2881 ttttagaagc aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca
     2941 atcatttttt tgtcttagct acgcaaaatc caatcgagta tgaaggaaca tatcctttgc
     3001 cggaagcaca gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg
     3061 acgaactttt gctactttta gataaattcg aaaaagtgtt ggataactta aatgaagtat
     3121 tgaacagtta tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg
     3181 aagtggcatc ttatgccttg cagttagtgt cagcaacaag aagccatgct gccatccagc
     3241 ttggcatcag tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa
     3301 tccatgggag aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt
     3361 cccatcgcct gattttttac gatcgttcat tgaaggaaga cgaaaaaaaa caaatcattc
     3421 atactcttgt tgcacaaatt cctgttcctg tgaggtagat tgaggtagat aatggaaaaa
     3481 atcaaagatt atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt
     3541 gctcttgtat tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta
     3601 tcatggagct tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg
     3661 cagccactcg tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga
     3721 actttttctt tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa
     3781 aaacaagaga ttttgattct tacaaataaa ccgcaagaag tccaattgct ttggcagcca
     3841 aaagaaagag gatgccatga aacattaact gtcattttta cagcctatga tagtctagga
     3901 cttttcagaa aaagtgcaaa aagagagatc tcttttcctg tgactgttct gcctgctttt
     3961 tgtaagattc aagcagaaaa attacagaga gttctggaaa aaaaacagca gctgaacgcg
     4021 taccaaagag gtcttgattt tcgggaacat cgcgcttatc gtccaggtga ttctttcaac
     4081 cgaatcgatt ggaaattgtc tgctcatact caagagtggt tataccgtga atacgattat
     4141 caagaagaag aatgttctcc tcttttttgc ttttggggtt cgcacagtcc aaaatttgaa
     4201 cctctgctag acttgtattt ttctttatgg catttgagaa aagaaaagca gccggaactt
     4261 ctgatattag gcaaccgcgc ctttcatggc aaagaccccg gtcataccta ttttgcttct
     4321 ttggaagctg gcgatgagaa agcttttttc gcacacctaa aaaaatatgc aaaaaaacaa
     4381 atcgtcctct ttgttcctga gaattctcct gaagtctcag aagctattga aacattgtca
     4441 aaagatcgaa cggtttatct tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa
     4501 gacaagatat gttcattgcc aggaggtgaa tggattgacg attaaatggg aaaaatggct
     4561 gtgtggcgtt tactcctttg tgatactaag tgtaggtgct ccgatatttg tagtagctaa
     4621 tcaattgcaa aacagctacc ttcttatcct aactattggt gtcctatgcc ttattgtctg
     4681 ctgtattcct aaaaaatggg tacgtttgct gctttctttg ccagtaatga taggttgttt
     4741 gtttttgtat tttccttcga agacattttc cttattatgg atcttacagt ttttttcgtc
     4801 agtcacagag gaattcttcc atctatccca aggtaaactt tattatttgc cagaaaagac
     4861 agcttttttt ctcataatgt tgctgatcta tttatttatt acattgaccg tggattacga
     4921 ctatttgtac gcaccctttc tttctttgat ggcttacttc atgatgctta ccgtttttcg
     4981 ggaaaaagat ttactgtacg aaatgattgc ggtagtaact gttttgttcg tgtatctggc
     5041 agcaaggcaa tttttctcca tgcggttgtt gtcgagaaac actcgattcc agtcattgac
     5101 tacagttctg cttatttgtt tcttaactat tagcgctatc ttgcctttat atcttccgaa
     5161 agtacaccaa tctctcgagg aaacgagtga accgatccga gaatatctta atgatgaagg
     5221 gctttatgat acactccatg agtatcaatt aaccggaagt gcaagaacag gcttcagtga
     5281 gaatgatgaa cagcttggtg gacctttata tgataatggc gaagttgttt ttacagcgaa
     5341 ccaaaaagga aatggctatt ggaagatcga aaataaaaat cattacaccg gttctggatg
     5401 gatagaagat caggacgcac ccatccaacc aatccaagaa ttccctgttg acatcacgag
     5461 ctaccaaacc gttatggaag acaaagaaaa cattacattg accctaaaaa aacaagcttt
     5521 cttaccttat ccttatggaa atactacctt gactgatttt tcattagcta gtggacaaac
     5581 gctttactat ttgcctgaaa gccagcgatt cattcctgtc ccgaatgaat cgacacgttc
     5641 tgcaacttta caaacagaaa ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt
     5701 aaaagctgat gatttagaaa atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa
     5761 acgtattgag gacttggcgg tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt
     5821 cgaagctgtc gaacagtatt taaaaacaag cggaaatttc cgctattcca aaacggatac
     5881 cggacatact ccgaaagaac acgattatgt ggattatttc ctctttgatt caaaagtcgg
     5941 ctattgtgac aacttttcaa cttctatggt cgtccttctt cgaacacttg gtatcccagc
     6001 tcgctggaca aaaggtttta caaatgggct cagaacaggc acagataatc aagggaatga
     6061 ggaatacagc attctcaata gtcatgctca ttcttggcca gaggtatact ttcctggatt
     6121 tggctggctt ccatttgaac caaccccttc atttgccaat ccaatgggtt cacaaccagt
     6181 tgctgaaaca accgaaaccg tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat
     6241 ggcagaaact atttccagtg agagatctga ggtcattcca tcagaagaaa caacactcac
     6301 accagcttat aaaatcgtct tattcagcct tggggtgtgt ttatacgtct tgttgttctt
     6361 tctattgtta ttcagaaaat ctctgcgctg gacaagttat cttatctatc ttcatttttt
     6421 tgcttctact aatacgattg catatcaaaa acttcttaac catttggaaa cattggtacc
     6481 gcgcaaaccc gcagaatctt tgcaggaata tagcctgcga atagaacaag aattcaagct
     6541 agatctgcgt ttcattcgat taactactca atatgaagca gaaatatatg gacgacaagc
     6601 agatccggta aatttcgata aaaaaaccta tttagaaatt acgcatataa taagaaaaac
     6661 ggtatacaaa aaagttctga caaaagggag ccgcttcaaa aaataagata aaatttctgg
     6721 agaatctact tctggaatgc cgagaaccag ctgcttgagt atcgattatt cgaaaaaaag
     6781 gttgtgacac gttttttgtc acaacctttt ttcattatta tttgattttc aatgtcaaag
     6841 catttagagc tacaactacc gtacttaacg acatcaagac agcaccaact gctggactta
     6901 atatgatacc aattggcgca agaattccgg ctgctagcgg aattgcaaga atattgtaac
     6961 ctgcccccca ccagaggttc tggatcattt tctttcgcgt ttgcttggct agatcaagaa
     7021 aatgcaaaat atcttttgga tcgctgtttg tcaatacgac atccgcagaa tcgattgcga
     7081 tatctgtccc tgcaccgatt gccatcccga ttgaagcacg ggctaaactt ggcgcatcat
     7141 tgatcccatc acccaccatg attacttttt tcccttggtc aaggtatttc tggacaacag
     7201 cttctttatc atctggtaat aaaccgccat aatattcttc gatccctaaa taatctgcta
     7261 ctgcttgggc agcgttttta ttgtcaccag taagcatgac aggagtgatt tttctttctt
     7321 tcaatgttcg gataaattct tttgcttctg tttttactac gtcacctaaa gcaacgattg
     7381 cagctagatg attttctaaa atcaggaagc tgatggtatt tccttgttct tggtaaggtt
     7441 tcaataatgc ttgttctacg tttaatccga gacgctcaac ttctttttca ttaactattt
     7501 tcacttgttg gtttttgact gttgcctcta gcccaactcc tgaaagattt tttagatttt
     7561 cggcttgata aggcttgatt tcatgttctt tcaaataatt cataatacca acagccaatg
     7621 gatgattggc attcgcttcc aatgctccta aatattgaag gatttcattt ttattgaacg
     7681 catcatcaag tacttcgaca cccgttacag taaattttcc ttctgttagt gttcctgttt
     7741 tgtccagcat gatcacatct agatcattgg cttgctccag tgcattgcgg tttttcaaaa
     7801 gtaatccgtt tttagctgct attgatgtag agcgagcaac aactaatggg atagctaaac
     7861 ctagagcatg aggacaggcg atgataaaga ctgttaccat acgttctaat gcattaggaa
     7921 gatctgtcaa gaacaaccag gcgatgaatg ccaggatacc cacaattaat gcgacataaa
     7981 acagccattt tgccactttg tcagataatg actctagctt ggatttttct ccttgtgctt
     8041 ttcgcaccat ttccataacc ttcgctagat aaccattttc accagttcca gttacttcga
     8101 tttcgatcgt tccatcccca ttgatagaac cgccaatcac tttgtcattg gcttgttttt
     8161 tgattcctct tgattcgcca gtcacagctg attcgtcaac aattgtttca cctttcaaga
     8221 ttacaccatc tgttggcatt ttatcaccag accggacgat caaacgatca ccttcgttta
     8281 cttctttcaa tgaaactgtc tcttcttttc catctttcgt caagcgtttt actgattctg
     8341 gcagtaattc tgctagtttt tgtaaagcat tgctggcatt cgacacagca ttcatttcaa
     8401 tccagtgacc tagtagcata ataacgatca aagtagccaa ttcccagaag aaatccatga
     8461 cgtgtgtatg tggattgagc agatttgcga taaacgaata gacactataa atatatgcaa
     8521 ctgtaatccc catcgcgatc agtgtcatca tagcaggact tttttgtttc aattccatct
     8581 tagctccact taaaaatggc tgaccgccat agataaatag tatagttgct aagatcaata
     8641 cgagccaatc agaaccagga aacgttactt gaaatggaaa ttccattccc atcattggtg
     8701 aaaaaagaat gattgggata gctaggataa gcgatagcca aaatttttgt ttgaaatttc
     8761 ccatgtgcat ggaatgatcc atgccgccat gatcgtgatc catgtgcatc gaatggtcca
     8821 tttgtttgct gtttgctata tctccatggt tatgtcccat gtgcatggaa tggtccatct
     8881 ggctatggtc atgtttcatc tccatctgtt tttcatgaga ttctgtactt tctttgttta
     8941 ctacttcttt tttatgttca tgtcccatgt gcatggaatg gtccatctgg ctatggtcat
     9001 gtttcatctc catctgtttt tcatgagatt ctgtactttc tttgtttact acttcttttt
     9061 tatgttcatg ttttttctcc atatcgttcc cattcatttt tactccatcc cttctcttac
     9121 tttttcatgt gccgatttaa gctcagggag ttcaacaata cactgacgga actaaacgcc
     9181 atcgctcctc ctgcaatgat tggattcaaa aagcctagtg cggcaaaagg aataccaatc
     9241 gtattataga caaaagccca gaaaagattt tgtttgattt ttctcaatgt caccctagac
     9301 aactcgattg tttgtgcaat ggatgccaaa ctgctactca tcagcgtcac atcggctgtt
     9361 tccatcgcga tatccgttcc acttcccatt gccataccaa catcagctaa tgctaaagcc
     9421 ggtgcatcat tgattccatc gcctgccata ccgacttttt tgccatcttt ctgaagtttt
     9481 tctacgtagg ctgctttatc ctctggaagt acttcagcaa agatatgctt tggatcaata
     9541 ccaacttgtt taccaatcgt ttcggctgcc agtttgttgt ctcctgtcag cataaaaaca
     9601 tctaatcctt tattctggag ctgcttgatt gcttgtttgg cttctagttt gatttgatca
     9661 gccacggcaa tcaacccgat cacttgcttt tcatcagcta aaaacatgac tgtttttccc
     9721 tgctgttcta attctaacgc gtgttcttgg tattcatcaa atgataggtt caattcaatt
     9781 aatcgtttac gtgtacccgc aaaatagcgt actccgttaa tcgtaccgct gattccagca
     9841 cctgggtgag ctgtaaaatc aatcatatcg tatgttgctg cttcttgcag ttttccgtat
     9901 tccacgattg ctttacctag tggatgttca gaagcttgtt ctaaagtata aaaaatagat
     9961 aggacttctt tagaaccgac tagatctgta actttgggct ttccttctgt aatcgtccca
    10021 gttttatcca aaacaatgct gtctaagtga gcagctgctt ctaatgcttc tccgccttta
    10081 attaaaattc catttcgtgc accaacaccc gttcctacca taatagctgt tggagtcgct
    10141 aaacctaatg cacatggaca cgcaatgact aatacagaga cactatggat caatgcgagt
    10201 tgccaatcac cagtgatcaa acctgtagct atgagcgtga taaacgcgat gactaatacg
    10261 atcggaacaa aaatccctga gatccgatct gcgatttttt ggattggggc tttgctccct
    10321 tgagcatctt ccaccatttg aatgatttgc gctaatactg tctgcttgcc gacttgtgtg
    10381 acttccatgt gtagcagacc attcgtattg attgtcccgc caaaaagcgt gtcatccgga
    10441 ttcttttcta caggaagatt ttcaccagta agcatacttt catctatcgc actgcttcct
    10501 gaaataattc gaccatctgc tggaatctgc tcaccaggac ggatgactag ttgatcacca
    10561 acgactactt cttcaatcgc taacgtttct tctttcccgt ttcttatcac ttgggcggtt
    10621 tttgtttgaa gagacatcaa ttgtttgatt gcattacctg ttttcgtttt tgctgtatgt
    10681 tccaaatatt tgccgagcaa aatcagcgtg atgatcatac tgctgctttc aaaataaaga
    10741 tcttgggggt gtccacggaa aaatccgttg taaatgctca atgcaaaggc agccgatgtt
    10801 ccaattgcta ccaatacatc catatttggt gctttcgact tgattgcatg gtacgcacct
    10861 ttataaaaac gagcaccgac ataaaattgg acaggagcag acagcactaa ctggacgatt
    10921 ggaaaatgaa aaaagtgaac aatcgccgca tggcttccta acatcatagc aatcattgac
    10981 aacatcaacg gcaaagtcaa aaccgtactc aatataagat cgaatagcat ttttttcaaa
    11041 tacgcttgct tttcttctgc aattttttgt ttgtgggctt catcgtacaa aattgcacca
    11101 tagccgatgt tttctacgct ttggattaat ttttcagtgg tcgtcccttc atatttgaca
    11161 cttgcttttt cagtggccaa gttgactgtg gcattgacca caccaggttg tccgttcagc
    11221 tctttttcga tcctagcaga acaatttgca caagtcatac ctgtaatgac gaacgtatcc
    11281 attttggttt ctgctgttgc catcaaatca cctctgcttt ataacccaat ccattgattg
    11341 cttgacaaat cttttcggat tgaacttttg tttcatcaaa cttgaccgta ccgtttgctt
    11401 ttttcaaatt tactttcact ttttgcacgc cgtcaagtgc gcttactgtt tcttctactc
    11461 ttgctgcaca atgattgcag ctcatacctt cgattgaaaa ttgttgtttc attttttctt
    11521 cctcctattg atgttgttta cattcacatt gacctgggat acagttacat tcgatcgtat
    11581 ctactggttg cttttgttcc agttgtttca aaatctcatt gatatcttct tgagtcaaag
    11641 tggcttcttc tactagatcc gcaatcgtct ctccaatcct ttttgcacag atatgggaaa
    11701 aaagattttc cgtcgcactg cgaactgttt ccatctccga gacagctgga tgataaatga
    11761 atttttttcc ttcttgttct gtccagatca cttctttttt taccaaacga cccagcaaag
    11821 ttttgatcgt tgctggtttc caatccatcg aatcagctaa gatctgcgtg atttcttggg
    11881 ctgtcgtctg tccaagtgtc caaataacac gcatgatctc ccactctgaa tcactaatct
    11941 ttactggcgt tttgactttt tccatttatt tcacaccttt cgtttacaaa tgtaatcatt
    12001 aacttatgaa tacagattac acttgtaaac aaaaactgtc aattattttt gctctctatt
    12061 ttcaatttag ttaaaaattc ttgtttctct cgtcttgttt taaggatgat cagtttattt
    12121 cttgcattag ctacttggat cagctgctgt atttttggtt cattgtttcc ttcaaaatgc
    12181 cagataaaag ataaaaattc taagtatttc ctgtttagtt tctccgaaaa tgattcaggc
    12241 atatctggcc gagatttttt gtttatcttt ctttttagag aacgccaaac tactcggtag
    12301 atggcgagat aacgcggcac tttaagccaa atgatcttat ctgcttcttt aatcctttcc
    12361 tctaacgtag aagtataatt tccttcaacg atccatgacg gattagatac cataaacgat
    12421 tgctgttctt gcaaaaacca cttttttgcc tgaatgcgga aagccggtga tttctttgat
    12481 cttccttgcg agggacgatt ttcccgaccc actttgtcca atcacgatga tcttcattct
    12541 tctccctcac ttctctttgg aatttggttc gatcatacca cttataacgc cgcaaaaaaa
//
LOCUS       DBBGRF010000078        11782 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000078 DBBGRF010000000
VERSION     DBBGRF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.078"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            508..1071
                     /locus_tag="ACIZD4_002615"
     CDS             508..1071
                     /locus_tag="ACIZD4_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991481.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1132..1497)
                     /locus_tag="ACIZD4_002616"
     CDS             complement(1132..1497)
                     /locus_tag="ACIZD4_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HGC5991482.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1573..1818)
                     /locus_tag="ACIZD4_002617"
     CDS             complement(1573..1818)
                     /locus_tag="ACIZD4_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5991483.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1888..2142)
                     /locus_tag="ACIZD4_002618"
     CDS             complement(1888..2142)
                     /locus_tag="ACIZD4_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991484.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2306..2629)
                     /locus_tag="ACIZD4_002619"
     CDS             complement(2306..2629)
                     /locus_tag="ACIZD4_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991485.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2816..2889
                     /locus_tag="ACIZD4_002620"
     tRNA            2816..2889
                     /locus_tag="ACIZD4_002620"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2850..2852,aa:Ile,seq:cat)
     gene            complement(3274..3771)
                     /locus_tag="ACIZD4_002621"
     CDS             complement(3274..3771)
                     /locus_tag="ACIZD4_002621"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HGC5991486.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3811..4620)
                     /locus_tag="ACIZD4_002622"
     CDS             complement(3811..4620)
                     /locus_tag="ACIZD4_002622"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC5991487.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4954..5811
                     /locus_tag="ACIZD4_002623"
     CDS             4954..5811
                     /locus_tag="ACIZD4_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGC5991488.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5804..6706
                     /locus_tag="ACIZD4_002624"
     CDS             5804..6706
                     /locus_tag="ACIZD4_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGC5991489.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6739..7089
                     /locus_tag="ACIZD4_002625"
     CDS             6739..7089
                     /locus_tag="ACIZD4_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HGC5991490.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7138..8061
                     /locus_tag="ACIZD4_002626"
     CDS             7138..8061
                     /locus_tag="ACIZD4_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGC5991491.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8139..9032
                     /locus_tag="ACIZD4_002627"
     CDS             8139..9032
                     /locus_tag="ACIZD4_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC5991492.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9070..9633
                     /gene="amaP"
                     /locus_tag="ACIZD4_002628"
     CDS             9070..9633
                     /gene="amaP"
                     /locus_tag="ACIZD4_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGC5991493.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9647..9835
                     /locus_tag="ACIZD4_002629"
     CDS             9647..9835
                     /locus_tag="ACIZD4_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGC5991494.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9848..10750
                     /locus_tag="ACIZD4_002630"
     CDS             9848..10750
                     /locus_tag="ACIZD4_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC5991495.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10782..11024
                     /locus_tag="ACIZD4_002631"
     CDS             10782..11024
                     /locus_tag="ACIZD4_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC5991496.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11280..11651)
                     /locus_tag="ACIZD4_002632"
     CDS             complement(11280..11651)
                     /locus_tag="ACIZD4_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991497.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4175 a         1985 c         2233 g         3389 t
ORIGIN      
        1 tcattggtcg ttgaatgggc tgaatagtag tgtataaaac aattttgtgg agcgtgaagc
       61 ttttatggta gaggaaaata cgaataaagt gatgttgata aaaagattcc tatcttgaat
      121 atgaatcgag atgtcttgaa aatgaatgag tttgaccaat cattatccta tcgaaattta
      181 cagtttcgtt cgattggtct gtcaattaat gaaaaagtaa aaaagaatat gttctaggaa
      241 gagggcggca catctaaatt tttaagtaac ggacagttca aatatcaagc attgaaagag
      301 gctatcctac tgtttgaagg aatacgaata tataaaaacg acaaagagga aaaagtagtt
      361 cattaaatcc cttcaagtga tgaaagaatg agatctaata aaacctgatc tttcatctgt
      421 ttttttaata acgtaataat ttttttattt tttgtgcttt cgccgttatt gtagagtgat
      481 ttagcattct tatttttaaa aataactgtg ttatatatta aaaaaggcat aatagttata
      541 agctttttta aagaatattt agaaattatt aattttcgtc tgaaaacaaa aaaagaaagc
      601 gttattattt tagtctattt tcaggggggg aaccttatga taaaaaaact atttttacta
      661 tcaatattaa cgctagcaat ggcaggttgt tctgactctg gcttagcaac tgaactgatc
      721 acaaaatcaa ctgaagccac gacagaggag ttaaaatgtg gaaacgatca cagtgactac
      781 agaggcttaa atcgacgatg catgggaata ttaggcagaa gcaattgtaa gcatcgatgt
      841 agtaatcgaa gaaggtgtag aagaagcaac agaaaaatca aaagaaagat caaaagaagc
      901 aatctgtgct gtgcatcgta tacagacgtc gaagatgcgg tacttttaaa ccacgtcagg
      961 agatgttcat ttatgtctag ggaagttggc gatgaaccaa aactagagta cgcttttagt
     1021 tttgcacgtg aggatgaaga taaccctaaa acttacgaca ttttagcttg atctaagatg
     1081 gttaaagctt tttaatgaag taagaggaga tagaaggctt ttctagttat attaggtaag
     1141 ataaattcct ttttgctcca aatttgctaa acattctgct agataaactt catcgtgttc
     1201 cggataaatc ggcacgttgc gctctacagt aggtaaatca aaaaatgctt cgcatgattt
     1261 gccacgatac ataggatttt tccactctgg tgctgggctg taaccacgtt tttccatttc
     1321 atccatgaca agctgatgat attggaataa tctataagga gaatagtgaa aaacataatc
     1381 cacagtagca tgtttctttc cccagccatt tcctcttaat gcacagcatt cccgatgttg
     1441 tcctaaaagc tgttgacgag gaagctttga aatcaatttt tcatgccata atcgcataga
     1501 aatgtctcct ttatatatag attgttaacc ttagacgtta aatgaaaaaa ccagcaccaa
     1561 ggctggaaaa aatcacttca gtttgcttgc tgtttctgag cgaccaatta ggtaatcaac
     1621 ggaaatatcg taaaagtcag cgatatagat taattcaatg atgcttggaa tttcttctcc
     1681 ttcttcgtac ttacgatatt tgaataaagg aatacttaac gcgctagaaa cagctacttg
     1741 agataaagat cggccagttc ttaagaaatt cagacgacaa cgtaaagtat ccagtaaaat
     1801 agcttcttcg atactcattt aatcaccttt cattatagta gaatagttat aatgactata
     1861 gaaagctaca catgcaatca atagtactca atgtttttta tttaaacgta tcaaataaag
     1921 aatgacgatc aataaagaca aaaccagtcc tgataattct tctataaaaa cactatcggg
     1981 ttcaaagtag ttgtaattaa aaactttcca cataaagtag atagccggaa gagtcaaaat
     2041 agctaaataa aaccgttctt tgttccaatt cataagataa acaatacttg cgaccagtgc
     2101 gaccgcaggc acccaaaaca aaactctcac caacgtaatc atgtaacgga ctcctcaacg
     2161 attcatataa taaaagataa catgttattg catacatcac aaatgaaatg ctaggaaaat
     2221 aaaagaagaa tagatcaatg aaaaatgaaa aagcagaaca gttttctgct gataagcagg
     2281 aactgttccg ctgaatgtgt cttatctatc gagaaaaaat caatggattg atatctaagt
     2341 aattcaatac atataaaaag aggacgatcg cattcactaa aaaggaaaga atgatgatcc
     2401 catagcgaat ggaaacatat ttaacaaata cttttgtttg aatacgggca tatctttttc
     2461 ctttatagct gagcatcatg acaagaagca aaagggtaat cacaccttga aaaatcattc
     2521 caataaacag aattcctgag gtttgataat ttaattggag aaaataagct gctgccgcaa
     2581 ctaaatcgaa taaaatcgca ataaatggca aaataatcac tcctaacatt gagaataaat
     2641 aaaagaataa cattttttct aaaataagca aataaaaatt aaagtaacaa aatagttatg
     2701 acacaagtaa aagaaataag aataacaata ttattttact tatattttga aacttgtgag
     2761 agtttgtcat tcgtgctata gttgaaaagt aacaaaaata aattttattt atgatgtacc
     2821 tttagctcag ttggttagag cagacggctc ataaccgtcc ggtcgtaggt tcgagtccta
     2881 caaggtacat aagaggttgt gaaaaagctg ccctgcatca agtaataaga acagccaagt
     2941 aaaaacagct tcttatgttt ttacttggct gttcttatta ctgcagatgc aagcttttga
     3001 ataccgttta aggaagaggt tgtgaaatca gcgttttgac ctgagtatta gcttaacaaa
     3061 cggaaaaata gttcctcata ttttgccgtt tgttaagcta ataccgaggg tcagctgatt
     3121 gaacaccatt taagaaagag gtcgtgagcc tgccgtttca ctctgtgtca taaaaaagcc
     3181 aatctacttt gatagaaaaa gcacgtagga ctaaaacagt tctgcgtgct ttttttattg
     3241 tgtgttaaat atcgtaaatg aagatagata tttttatgat tcgacgatag agacgttgaa
     3301 atctttcaac agctctaaag cggattctcc gtgttttcta ctggagacta acattggatc
     3361 aacaaaaaag tctgcttcag gaaaagcact ctgcaggcct atcagattag agagtacaca
     3421 caagtttgtt tcaatcccga ctacttcgat ctctttttgt tcttctttgc tttcaaataa
     3481 agtttcctgg atttcagcta aagtttcagg tggaatcgta aagtaatact ttttaatcac
     3541 tcgttcattt tcttgtggag aaagaagagg gatcaattgc aaatcttctc gttcttcttc
     3601 tttgtccttc agttcaactg gtatatcccg tgtgaagaga atatattcat tattttggcg
     3661 tgctttagct aatctttgag caatacgttc tgccaattga tctgactctg gaatataaaa
     3721 ttcgctgttt ggatcaagaa tatgattttg catatcaata ataactaaca ttttctttcc
     3781 tcctacattc atatcgtcat tttattcttt ttaatagaag ttttttaaaa tataagcaac
     3841 accagcttct tcattcgtca gtgttacttg gtttgcaatt tcttttactt gtcgctgtgc
     3901 attccccatc gcaatactca acccgctgta attcaacata gcaatgtcgt tttcttgatc
     3961 gccaaaagcc atgatgtcac tcgattcgat tccaaggtaa tccgccagaa aaacaagtga
     4021 atgagcttta gtgatacctg taggcgtgat ttctaagaaa tgcggatcag agaatactga
     4081 ttggatacca tctgcttgca gatctctttg tagcttctgt agtttttctt cactcttatc
     4141 tgttaatgct aatttaagat agctaagaga aggatcttcc aacatattta aaatttgatc
     4201 aaaagaatgg ttctgtaaat tgaaatgttc ataataaggg tcatctttga ctagatttga
     4261 ttcatcgaat gtcagctgat catcttgggt ttctcggcta gcaatgatgg atattttcgc
     4321 ttcttgagca tagaagaagg cttttctcag tgtatcgcta tctatttttg aacgtctgag
     4381 aactttcgcc atttttccat ccttcatttc agcaatcagt gaaccattgg aagaaatcaa
     4441 atagccaccg attcctaatt cggaaaaaat atctttagca gaaatgctgt tccttccggt
     4501 agcgacggtt acgattccgc cattttcatc aaatttccga agtgcttgga tattttcttc
     4561 tggtatcttt ccatttcgat caagcaaggt accgtctaaa tcaatcgctg ctagtttcat
     4621 tttatcttcc tactttcttt ttacatatct attttcctgt taccttaaga ttaaatgaga
     4681 atttaaaaaa atgaaactaa cttgctttgt cattatgaat tttttcaaaa aacattctta
     4741 agaaaaaggt ggctatatat agtagttttt ggtcaatacc tttgaataaa aagccatgaa
     4801 aaacgaatag ttagcgctta ccgatgcgtt ttgtgataaa aaaattttaa aatattcaat
     4861 gaaaacaaag catatatttt gctttaaaac caaatgagga atattctaga tgtagaacag
     4921 gttagaaaaa gattagaaaa aggagtgatt ttgatggaga agagatacgg cgtagttcct
     4981 gtggtaactg cttcagacga aaattatgct ccttacttga gcgtgatgat cgcaactgca
     5041 ttagaaaatt gcaataaaac aagacgcata aaattttatg tgattgacga tggtctatca
     5101 gaatatagta aagaaggatt ggaagaaacg gtaaataaat attcaagtaa tgcaagtatc
     5161 caattcctga cagtggaaaa agatatctac gaagacttcc tagtcagtga ccatatcaca
     5221 actaccgctt acttaagaat ttctttacca aacttattag ctaaagagga ttataagaaa
     5281 gtcctttact tagattcaga tgtgttagta ctagacgata tcgtaaaact atatgatgag
     5341 ccgttaaatg gaaaaacaat cggcgctatt atcgatccag gccaagtgaa agctttggaa
     5401 agattaggaa tcgattccga tgacttgtac ttcaattcag gagtgatggt gattgacatt
     5461 gatcaatgga ataaaaaaga aattacagaa aaaactatcc attacctcag tgaaaatggc
     5521 gatcgaatca tctatcacga ccaagatgct ttgaatgctg tactttatga agattgggaa
     5581 caacttcatc caaaatggaa catgcagact tcgctgattt ttgaacgtca tccagcacca
     5641 aatgaaaaat atgaacgtca gtataaagaa ggaaatgaaa aaccttcgat cgttcacttt
     5701 acaggacatg ataaaccttg gaatacgttg aaagatcatc cgtataccaa tttatactta
     5761 aaaaaattag cacacagtac tctaacgaaa gtaggcgaga tcaatgaata aaaaagaaat
     5821 agcagtagtc gcaagttgta acacaaaatt cgtaccacat ttagctgcat tatttgtctc
     5881 agtattagat aattgcaacc cgtctaaatt tgttcggttc tatgtgattg acgatgatat
     5941 cgattttgaa agtaaacagc ttttacgctt ctcagtgaaa aacgcacgaa tgaactcaga
     6001 tgtggaattc ttgaaaatca ataaagaatt ctttacaaat gtggtaatca gcgatcgtat
     6061 tccagaaaca gcttattatc gtattgcgat tccggaattg ttccgcggca cagaagttga
     6121 acgtatctta tatatggatt gcgacatgat cgctttacaa gatatctcta aattatggcg
     6181 tcttgacttc ggtgattcaa tcgtagcagc tgttgaagac gctgggttcc atcaacgact
     6241 ggaaaaaatg aaaatttcag ctaaatcaat gcgttatttc aactcaggtt tgatgctgat
     6301 caatgtgaaa aaatggttag atgaaaatat tacgcaaaaa gtattagatt tcatcgaaca
     6361 taatccagaa aaattacgat tccatgacca agatgcatta aatgctatct tacatgaccg
     6421 ttggttacca cttcatccgc gttggaatgc acaaggctat atcatggcaa aagcaaaaaa
     6481 acatccaaca gcagcaggtg aacgtgaata cgaagaaact cgcaacaatc cttacattat
     6541 ccatttttca ggacatgtga aaccgtggag caaggatttt gaagggccaa cgaagaaata
     6601 ttacgaaaaa tatgcaggga tgacggcttt ccgttgtgta gctaaattcc ctaaatatcc
     6661 aaaatatgca aaagttcaac caaaaacaga tgtagttgtt aaataataga agacaacaac
     6721 tgaagagggg gagtaggaat ggaaattaca atgtctaaaa atgcagtaga gacgttaatt
     6781 gaaaaggttg gggaaaatac aaaaatcgca ctcgcgctta tcaatgattc cgatccattt
     6841 ctaagggaca aaggtgcttt tgcaaaaggc agcttttttc aaatcattcc ttttgtttcg
     6901 gaatttggag aatatgcgac taaaatcgag catccattat tggacatcta tacatctaaa
     6961 ttagagcaaa attatttcgg taaacgattg aacatggact tcaacaaaca gcttgacagc
     7021 ttttcattag aaaatgaaat cgcagtactc gattataata tcaaattaaa gaactgcttc
     7081 ttcagctaat agtttcgaga aagtccaaaa aggaggtata cattgagata ctactttgtg
     7141 gatgaagaaa agaatgtaat agaaacagat gaaaaaaaat ataattggct cgtacttgat
     7201 agtgcaaagc ccgaagagat tgagcaagca atcgaagaat tcgagcttcc tgatgatatt
     7261 ttcgtaggaa ccgaatatcc ggaagaagtt tctcggatgg agcgccttta tgagacgaaa
     7321 ctagagcatc cattttcttt ggtagtgatt aatctagatc agtcagataa tcgtatcgaa
     7381 aaaaaattaa cgccaatatc ttttgtactt tccgataatc tcttgattac ttgtatcgat
     7441 agaaaaaccg aatttgtgga tcggctgctg acaaagcatg gaaatcattt aaactcgttt
     7501 gaaaagatca tcacgtatac attattagat atttacaccc attacgtgaa agaactaaga
     7561 gagatgaaaa agcgaattga cgctttggat aaagcagctc gtaaaacaac ggaaaatgaa
     7621 gaactgtata aacaggcaga tcttgaaaga gacatcgtat atatcgatca taccttaaga
     7681 gatcaacggg aaacaatgga tcaattatgg aattctgaaa ctttcatcaa acgtttagac
     7741 gatgaacagc tactctatga tgtccatttg agacagcgac aaacagaaaa aatgatcgag
     7801 atctatcgag atttattaga gagtattggt gatctattca acgggatgat ggacaataat
     7861 ctaaatcata tcatgaaata tctagattca gctgcattaa tcatttccgt tccggcgttg
     7921 ttcgcaggga tttggggaat gaatacagga ggattaccgg gtaaaagttc tgctctaggc
     7981 tttatactcg tagtctttgg ctctttgata gcagcagtag ttttaggtta ccatttatac
     8041 cggaaagatt atacaaatta aagaatctat ttaaaacagg tatcaaacaa agaaatttgt
     8101 tttggcaata caatttaaaa actaggagga atacagcaat gacagaacca aaattaatcg
     8161 acccgcgaaa cttgtaccat acggagaaat ttcctaaaca agatcaggat acaccagctt
     8221 tacagcagaa tatgattcct gttcctgatt gtggagaaga atcctatgaa ggcaataatc
     8281 aactagaaaa ccgccgtgta ctaatcactg gtggagattc agggatcggt cgtgcagcag
     8341 cgattgcatt tgctagagaa ggggcagata tcgctcttca attcttccca ggagaagaaa
     8401 aagatgcaga ggaagtagca aaatacgtga aagttgcagg acgtaagatt gtcttactac
     8461 cttttgatct tcgtgacgaa caagcaccta aagaaatcat agataaagcc gtgagtgaac
     8521 ttggcgggct agatacgatg gtactaaacg caggacagca aatttcttgt cagtctattg
     8581 ctgagttacc acttgagcaa gtcaaagaca catttatgat aaacatcatc gctatgtttg
     8641 ctttagtgaa agaagctgtt ccgcatatcc cagcaggagg agcaatcgta acaacaactt
     8701 ctgttcaagc attcaatcca agcgaacatt tattagatta cgcagcaaca aaagcttcaa
     8761 tcgctaactt tacgatcggt ttagcaaaac agcttgcacc taaaggaatc cgtgtaaatg
     8821 gtgtagcacc tggtccaatc tggacaccat tacaactaga cgaaggacaa ccttctgatt
     8881 cgatccctga atttggtcag caaagtttac tagaacgtgc aggtcagcca ggagaattag
     8941 caccagttta tgttttctta gcatcgaata aagcaagtta tgttacagcc caaatttacg
     9001 gagtaactgg tggagaagcg atcaacttat aagaagttga tcgtttcacc cctatgagga
     9061 ggtgcgaaaa tgaataaagg tgtaaaaacg atcggagtga tcggaacatt acttttgcta
     9121 tctgtgcttt tgtttgcgat actattaagt gcaacctatc cattgccttt tcagctagag
     9181 aagtttcgat tcttttccat cactaattca tacgtgcaac aatatgtatt ttggcttgcc
     9241 gttgcatttg ctattttgac aattatcacg ttacttgttt tcctgtttta tccaaaaaca
     9301 atcggaaact ttctactgaa acatggtgat ggggagttga cgttggataa aaaagcaatt
     9361 gaaggaatgg ttcgttctca cttgcatgaa gatgaattca tccattcacc aaaagtaaat
     9421 gtcaaagcaa cgaaaaacaa gatcgccgtc aatgtaaaag gggagttgaa acgaacttca
     9481 gcactcattg gtaaaacagg aacattgatg aaagaaatcg aaaatgaagt acaacacata
     9541 ttgggaacaa aagagccagt gaaagtatcg gtgaaataca caggctttga agaaccagct
     9601 aaacgaagca atgaccgcaa acgagtagaa taggggggga ccaaaaatga aagaactatt
     9661 ttcgacatac aagctcccta tcatctttgg ggtacttgga ttgatattag ccgttttatg
     9721 gatcaccgtg ggctttttca agaccttatt gatcttgatc atggcagcga tcggcgtcgc
     9781 tatcggtttt tatctgaaac aaacgaaaat cttagatcac tattttaaat cttaggagga
     9841 aacatccatg aataacaata acaaaaataa taacaataaa atgaacaacc aaaaaccagt
     9901 gtctgcacat ccagacccaa cgacaccaaa ccaatcaaat ggtgtgaacg atgaaaagaa
     9961 caaaacagca ccagtatctg cacatccaga tccagtagtc cctaacgttc aacaaggagt
    10021 agaagagaag aaacatgatg cagaaaagca tgcacctcat catccaggaa ctccagaatc
    10081 taaagttcca gaacaacatg atgcaatcga tccttctaaa cctgtggaag agcaaaaaca
    10141 tccttctgac catgcgaaag cacaagaaaa acttagttct gaccacacaa acggacaagg
    10201 aaaacttggt tctgatcata caaataacca aggaaagcat gattctgaac aggaagattc
    10261 aatgcgcggt gagctgaatt atgaagataa agttgtgcaa aaaatcatcg gaatcgcaat
    10321 tgaacaagta gacggtttat tatctgcaaa cggtggtttc ttctctaatg tggcaggaaa
    10381 acttgtgaat acagataatg taacggctgg gatcgaaaca gaagtcggta aaaaacaagt
    10441 agcagttgat atggatgtca ttgtggaata tggcaaagat atcgaaaaaa tctttgaaga
    10501 aatgcaagaa gtaatcggca aagaagtaaa aaatatgaca catttagaag tgatcgaagt
    10561 caacgctaac gtagtggaca tcaaaacaaa agaagaattt gaaaaagatc aagaaacggt
    10621 gcaagacaaa gtaactgacg cagcgaaaaa aaccggtgaa tttgcttcga atcaaacaga
    10681 taaagtaaaa tcagcagctg gaagcggcgc acaaaaagta aaagaaaata cagaaccacg
    10741 ggttcagtaa taaggaagta aaacattagg aggaacgaaa catgggattt atttggtcac
    10801 ttatcgtcgg aggaattatc ggagcaattg caggagcaat cacgaataaa ggttcttcga
    10861 tggggattat tgcaaatgtc gtagcaggtt tagttggatc agcacttggt caagcattat
    10921 taggttcttg gggaccaagt attgcaggaa tggcaatcgt gccatcattg attggtgcca
    10981 tcattttagt actaatcgta tcattctttg ctcgaaaact gtaaaaagac ttttaaaaag
    11041 aggtcgtgaa aaagctgttc ttcatcaagt aataagaaca gccaaacaaa aatagcttct
    11101 catatttttc atttggttgg gcatattatc gaagatgcaa gcttttgaac actgtttata
    11161 cggaataaga ggctgtgaca agacttttgt cacagcctct tatttatgcg ggcaaattcc
    11221 caattagatt tttaaaagtt tttccttaaa tgtgtcttta ttgatacaga gaagcttctt
    11281 taataaaaca atgcctccct aaattttctt gagataggaa aggtgaacat acaaaataat
    11341 acgaccactt tgaaaaccca gatgatccac aaatggatcg tatgatactg atgaagtaaa
    11401 aagcaatgga tcagaaactc aaagagattg aaaaagacaa ggaagaaata atatctcttt
    11461 tttactcttg tctgttttag ccaataatag ctcgtaaagt aatctagaca aacaaataga
    11521 agtaaacaaa gtttcgtaag agcagcaatc gtatcatgtt gctctgctag acgattgacg
    11581 agcaggaaaa atgttggtaa tggaatatag atcacgagta atgaaagaaa aaagtaaaca
    11641 ataaatggca tactattcct cctaattgtg tgagttcgcc ctcattttaa aataacgata
    11701 tttgtttgtg aagctttttc gtgtcgtaac aaatgttatc taatgtattt ttaaataaat
    11761 aatcattatt atcaaaataa tg
//
LOCUS       DBBGRF010000079        11445 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000079 DBBGRF010000000
VERSION     DBBGRF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.079"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            185..1183
                     /locus_tag="ACIZD4_002633"
     CDS             185..1183
                     /locus_tag="ACIZD4_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC5991498.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="ACIZD4_002634"
     CDS             1295..1804
                     /locus_tag="ACIZD4_002634"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HGC5991499.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="ACIZD4_002635"
     CDS             complement(1834..2493)
                     /locus_tag="ACIZD4_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGC5991500.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="ACIZD4_002636"
     CDS             complement(2495..3259)
                     /locus_tag="ACIZD4_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGC5991501.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="ACIZD4_002637"
     CDS             complement(3267..3944)
                     /locus_tag="ACIZD4_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGC5991502.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="ACIZD4_002638"
     CDS             complement(3981..5366)
                     /locus_tag="ACIZD4_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HGC5991503.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="ACIZD4_002639"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACIZD4_002639"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACIZD4_002640"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACIZD4_002640"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGC5991504.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="ACIZD4_002641"
     CDS             6305..7162
                     /locus_tag="ACIZD4_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991505.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDGTEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="ACIZD4_002642"
     CDS             complement(7243..7578)
                     /locus_tag="ACIZD4_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991506.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="ACIZD4_002643"
     CDS             complement(7645..9015)
                     /locus_tag="ACIZD4_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGC5991507.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="ACIZD4_002644"
     CDS             complement(9093..9629)
                     /locus_tag="ACIZD4_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGC5991508.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="ACIZD4_002645"
     CDS             9938..11419
                     /locus_tag="ACIZD4_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991509.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3517 a         2300 c         1855 g         3773 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatggtactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttatt
//
LOCUS       DBBGRF010000080        11337 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000080 DBBGRF010000000
VERSION     DBBGRF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.080"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(364..1482)
                     /locus_tag="ACIZD4_002646"
     CDS             complement(364..1482)
                     /locus_tag="ACIZD4_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991510.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1715..1837
                     /locus_tag="ACIZD4_002647"
     CDS             1715..1837
                     /locus_tag="ACIZD4_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991511.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            1953..3260
                     /locus_tag="ACIZD4_002648"
     CDS             1953..3260
                     /locus_tag="ACIZD4_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGC5991512.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3379..4578
                     /locus_tag="ACIZD4_002649"
     CDS             3379..4578
                     /locus_tag="ACIZD4_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HGC5991513.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4605..5873)
                     /locus_tag="ACIZD4_002650"
     CDS             complement(4605..5873)
                     /locus_tag="ACIZD4_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HGC5991514.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(5928..5994)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(6036..6682)
                     /locus_tag="ACIZD4_002651"
                     /pseudo
     CDS             complement(6036..6682)
                     /locus_tag="ACIZD4_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7090..7593)
                     /locus_tag="ACIZD4_002652"
     CDS             complement(7090..7593)
                     /locus_tag="ACIZD4_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGC5991515.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7716..8480)
                     /locus_tag="ACIZD4_002653"
     CDS             complement(7716..8480)
                     /locus_tag="ACIZD4_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGC5991516.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVISLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8588..8863
                     /locus_tag="ACIZD4_002654"
     CDS             8588..8863
                     /locus_tag="ACIZD4_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGC5991517.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9301..10251
                     /gene="yidC"
                     /locus_tag="ACIZD4_002655"
     CDS             9301..10251
                     /gene="yidC"
                     /locus_tag="ACIZD4_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGC5991518.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     IDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(10430..10609)
                     /locus_tag="ACIZD4_002656"
                     /pseudo
     CDS             complement(10430..10609)
                     /locus_tag="ACIZD4_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3401 a         2386 c         2002 g         3548 t
ORIGIN      
        1 taaacggtgt tccagaagta gcttcttcgg aaataagccg aaatttcaca aaaatttgag
       61 aaataatttt tgtcaatctc ttcttatttc ttgaagctga ccacttctgt cacaacctct
      121 tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaccaaa caaaaaatat
      181 gaagagctat ttttgcttgc tgttcttatt acttgatgca gaacagcttt ttcacaacct
      241 ctcatacacg gtgtttaatc agctgacctt cggtattagc tcaaaaaacg gaaaaatatg
      301 tgaaactatt tttccgtttg tttctctaat actcaggtca aaacactgat ttcacaacct
      361 cttttaataa cgaagaatcg ctgtcagact cttttcatct ggcgcatctt tttgatccaa
      421 aataaacact ttcccgccat taatgatcac atcatctgct aatgcattca gcacttgacg
      481 ccgatcatat tctgtttcag gatcttcacc gaaaccatca gctaagtttg acgtagcgat
      541 aaataaatgt gacacttttc cttctttcgc agctggaacg atatcaacta actgatcgat
      601 gaatttctta tctaagagtt tattgtattc ttttgattct tgagctgcga gttcacttga
      661 cagcttcttc gccccttctt cgatatctct aaaggatagc tgcgcaggag aagcagaaat
      721 cgcaacgtct gcacaataat agggattttt agcaattttt ttgaacatcg tctgattttc
      781 tggtaatgca aataaataaa tcggccattg ttcaggattt tcgaaagaat ccttcaagta
      841 cgtatcaaca gcttggtaat agttgaccca atcgatctct acttcttcat cttttggatt
      901 tacgccatgg aaagttactc catctcgggc tccgcctcct ccattagaag agaagttcaa
      961 accgccacct gtcagttcag atcccaatgc agtaacgaca tcaaccggtg ccccttctgg
     1021 tagagatact tcttttactt gtttgttgct gacctcatac aatttcatgg agtcgcggtt
     1081 caatcccaat aaataataag aatagttgaa ctgcccattt ttgataatag ccagtaaata
     1141 aggaagatca cttacatagt attgatcgtc taccgggata ctcaaacgat ggatataggt
     1201 ctggtcagca gttataatga ccgctacact cgtagttgca ctacgccaaa acgaaggatc
     1261 tcctaacaaa ttttcaattt tttcttggaa cggggaccag tcatgttcgg aatatttttt
     1321 ctcaaaacgt ttctttgctt ctttcgcaaa atttttgaat ttgatctgat ctttttccac
     1381 atcttgatgg gcgacatgcg tattcagcat gatcgtgacg aatggtcctt tagcgccttc
     1441 tgaagtcaat tgtgtcaata attctttatc cttttttgcc ataaacgtac ccctcctaaa
     1501 aaaatcattc ctttgtttct atctaaagtc taccacaaca ctatttttcc atacaataaa
     1561 acgtatctaa aaaaataaaa cggtttctac ggttttaaat ttagctattt ttttaagtta
     1621 tcttcataat ttcctcaatt atttagcccc agtcttcaac tattcttcat gaaatgctga
     1681 taaactaaga aaaagaataa aagaggtgga tcttatgcat ttgattatga ttttcagttt
     1741 attaagtatt atcagtttat ttgctttcag cgcttcccgc ttattagatg cggaaacaca
     1801 gcctattcct gtaaaagtac gtaaaaacga ccgctaaact tccataacgc gcgttcttat
     1861 cctaaagttt tttcagaaac attgaaactc tctcccctct ctgataaaat tttaatttgt
     1921 agcgaaacaa attaattaca aggagatcgg atatgtccat aaaaaaaaca cgtctagtcc
     1981 tattattggc tagtctcatt ctttgccttg cttcttttct accagctgtt gctgtgcaag
     2041 ctgaagatac gttcaaagta aatgcaaaag cagcttttgc tgtagatgcg caaagcggta
     2101 agattcttta tgatcaagat ggagaaaaaa ccatggggat cgcttcaatc acaaaaatca
     2161 tcggtcttta catcgtcctt gatcaagtaa aagaaggaaa actgtcatgg ggtgataaag
     2221 tttcgatttc agattatgca gaaaatttga gtatcacccc agatttatcg aatgttcctt
     2281 tgcataaaga aaacacctac actgtcaaag aattattcga ctctgcaatc atccagtcag
     2341 ccaatgcttc aatggtggcc ttggcagaaa aaatctctgg cagcgaagct aaattcactg
     2401 aacgaatgaa agaacaattg aaagattggg gaatcaaaga tgcaacaatc gttaatgcat
     2461 caggattgaa caactcttat cttggcgaaa accgaccaga aggcactgga gaaaacgacg
     2521 aaaatcaaat gtctgctcaa gatgtggcca tcgttgcccg ccatttgatc ttggatttcc
     2581 cagaaatact ggatgtatca agtactacga cccaaatgtt tggcgaaaat acgcaatcac
     2641 cagtggaaat ggtcaactgg aactggatgc tcccaggatt cgttaattac aaggaaggcg
     2701 tggacggatt aaaaactggt acgactgagc ttgcaggtgc ttgtttcgtt ggtacgatca
     2761 ctaaaaacga tcaacggatc atcactgtcg tattgaatgc ggacggccat gcggaaaacc
     2821 cgagtgcccg cttcaatgaa acagaccgtt tgatggacta ctgctatgac aattggtcag
     2881 aaaaagagct cggaaaagct aacgcaagta ttcctagtct aaaaaccatt gatgtaaaag
     2941 acggaaaaga atcaacagtt cctgttgtgc ttaaaagccc tgtaaaagta tgggtacgaa
     3001 acgatatgga tactggcaaa ttaacgatca cgccaacact tgacaagaag caagtcactg
     3061 acaatgagat ccaagcacct atggataaag gtacaaaaat cggtaccgct acgatcacct
     3121 tggcagacga taaattaggc tatttagaag acaacaatgc accatcaaca gagatcatta
     3181 cggataaaac agtggaaaaa gcgaatatat tcgtgattgg ctggcgacgc gtcgcagaat
     3241 ttttcggcaa cttgttttaa ttgaacaata agaaaaacat ctttccatcg gaaagatgtt
     3301 tttttgcttt ttctagttta aataacagct tttttcatct attttcgtta tactgtataa
     3361 gaaaaaggag ttgaatttat gaatctaacc agagatctga tctttttagt tctctatctt
     3421 attggggtat tctctatcgt ttattggcga aaacagaaga aggatccttc cttgttcttt
     3481 tacggcagta cgtggacatt tacggtaatc ttaacttatt ttgtcgtgtt ggaaattttt
     3541 tattcgacct tttatttttt gattccattg ttgttcttta gtatctttgc tttttcttat
     3601 ttcacagaaa aacgaaggct actgaatggt cttttattca atgttttact catcagtttc
     3661 ggcatctact tgtttgtctt gctgtatgaa acgcaaaata tttttcttgg cggactgatc
     3721 gccttgatca cgattccatt gctacttgtc cttttatttg gtatttatgg attgattgtt
     3781 tttctttttt ggaacggggt cacagtttta cgtagagaat cgcattcatt agctaatctt
     3841 ttaacgttga tactagccat ttttcttaca ctgtttcttg tttttgactt tttcttgtta
     3901 aaatatttgc cgcaatggat aaatgctttg tttttctgcg ttcccctgat cttgatctat
     3961 ctatttatcg tattctacaa ctttttgact gtctcattct tgtatcagtt caaccggcct
     4021 cgatacaatc aagacttcat cgttgtgtta ggcgctggat tgatcaatgg agaaacagtt
     4081 tctcctcttc tagccaagcg aatcaataag gcaattgctt tttatcgggc tcaaagccgt
     4141 gctacattaa atccgcccat cttattgatg tctggcgggc aaggagcaga cgaaaaagta
     4201 ccagaggcca ttgcgatgaa acaatatgcc atggaacaag gaatccctga aagagacatt
     4261 cttgtcgaaa ccaattcgac aaccactttg gaaaacatgc tctattcaaa ggaaatcatg
     4321 gatcagcaaa tgaaagggcc ataccgcgcg atctttagtt ccaacaatta ccacattttt
     4381 agagccggtc tttatgcgcg gcaagccaaa ttgaaagcaa atggtattgg tgcaaaaaca
     4441 gctttctact acttgcctaa tgcgttttta agagaatacc tcgccatctt gatgatgaac
     4501 aaaaaaagac atatgatcat ttgcggattg cttttcgcag gctccgcatt cttatcgctg
     4561 attactttac ttttctaaaa aaacaaggtg tgacaaaaca tatgtcacac cttgtttttt
     4621 tctttcattc tcttaactat tggcaaaaag agtatccctt ttttgaccgc tacttgctga
     4681 gcagaataaa taccgctgtt gcctgaacac ataaagctga tcaagcagat cataaagaag
     4741 tatactgccg cttgtgaacc gaacaattcg atccccatca caaagcaggc aatcggtgta
     4801 tttgtcgcac cagaaaatac tccgataaag cccaatcctg caagaaaagg aacagaaaca
     4861 tggagcaaag gcgctagtgc tgcaccaagc gttgcaccaa tttcaaacaa tggtgtcact
     4921 tctccccctt gatatcccgc gcctaaagac aaaactgtga agaataactt cccaataaaa
     4981 tcatagacat gtgcctgtcc attaaatgat tcttgaagta acggaagact caatccgaga
     5041 taacgttgtg tttgcaaaat caatgctgct gccacaacta cagctccacc tatcgtattt
     5101 cgacaaacag gatgaggaat ccattgtgca tatcgcgctt ttaaaaagac gatcgaacgg
     5161 ctgaataccc aaccaatcaa accaaaagca atcccagcaa caaaaacttt gaagaacagc
     5221 aacatactcc attcaggaat cacacccatt tggtaatgta gatgagaaac accatagctt
     5281 tctgtcatga aatttgcaaa cagtgcagca aagaagctag ggaagatcgc ttctgttcgg
     5341 actttcccga ttgccaacac ttctaatcca aataatgttc cagctaaagg tgtgccaaat
     5401 acagaactaa aacccgcact gattccactg ataatcaaga tttcccgttc tgatttatcc
     5461 aatcggaaca aacgtgccgt attatctgct aacgctcccc ccatttggac tgctgttcct
     5521 tcacggccaa cagatccccc aaataaatgg gtagttatgg ttccaaacag tgtaagtgga
     5581 ataagccgca acgggatttt ttcttctcca ccatttcctt gatcgatcac taagttgttt
     5641 ccacgactag aaagtccgcc gtgatacgca tagagataag caaaaagcgc accactaact
     5701 ggtagtagac aaaggagcca aggatgtgat agtcggatat ctgtcacaac tgtcaggcta
     5761 tttaagaaaa aagcagacaa gctccccatg aatataccga gaatcgctgt gatcaccagc
     5821 cacttcagca tatacactaa aatgcgtact ggactcggta attgtttttc cataaaaaat
     5881 tcctcctcaa taaaaaaacg cctactaaag aaaggggctg tccccagact ttagtaggcg
     5941 tcattagcta tctttcgtta gcatttaaag gcgaacacca tcacctattc acttccatta
     6001 aaagatagca tatttttctg taaaaaacaa taaaattatc gttctttctt tacacgttca
     6061 gcaaattcat agaaaggagc caatttcgtt aactgttgat tacattggtc actatcatga
     6121 caaatataat tccccttttt cgtatacgtg ccatcagaac ctgctttcgt tgtagaaaga
     6181 aaaagcgaaa cattcgatgt tttctgacag attgcacaga ttcccttatt tatcgttggt
     6241 gataaagtac cgctaatccc ttttaatttt tcatcttcgt aatagaccat gaattttttc
     6301 tgcgtacctg gatcattcca gccgatgtac gtatgttctt gcaagtcgat ttcattccaa
     6361 gctggttgtt tgagtttttt cacttttcgg aataatttct cgatttgtgg tttgctaggc
     6421 tgcataaacg gctgaacgat ttgcttcagc tcctccaatg ctctttctgc ttgcgctttt
     6481 gtcagtttta cgtctaaaac tgtcgttaaa aatgtatcga ttctggcagt tcgtgatcta
     6541 atatgtctcg aatcttttca gctgctagtg cctgaactgt ttgtaccgtt tttggatcat
     6601 tgacagatga gtacgcattt aataactgtt ctacttctct tattataaaa aaatattggt
     6661 atggttttat tgtttgttcc atgattttaa agtcctttct tctaaccaaa gtgcatactt
     6721 tgtagaaaaa agtgatcttc tgcaaagtat gtgttacctg aagatcccgg actcttttaa
     6781 ataagatacg ttttgcatct tatcatcacc ccctttaatg cttattattc tatgtacatg
     6841 attcattcga taaataaaag taaaccgtat cttgaacaga tagtcaactg caaacagaaa
     6901 aaaggactgt gacaaaagtc gtgtcaaagt cccttgtttc gaatgaatgg tgttcaaaag
     6961 ctggcatctg cggtaataag ccgaaacttc acaaaaattt gagaagcaat tttcgtaaat
     7021 tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tcaatatggt ctattattgg
     7081 ttttatctat taaatcgagg attctttccc aaagtaacgt tgccatctct tacgcatact
     7141 tgctgacata ggctgagcgg cttctttgac tgcgcagtat ttgtctacga atgttacgat
     7201 atatccttct ttgtacttag gcggtgcaat cgttgcgccc cacatgtgct tcaaaatgat
     7261 atctcgctca agatccgaca attcggtgat cttttctgca ttctttacag caattcttgg
     7321 atggatatac gcatgtgtgc cttcatcaaa tttcgtcgta cgccaatcat agtagaacag
     7381 atcatgcaaa agtccagcac gcgctgttgc tttagcattg ccaccccatt tttttgcgag
     7441 cagataacta tagtaagaaa cactgatgga atgctccaaa cgagtggaat gaacatgctg
     7501 tgtgtaattc gctaattttt tcactgcttc tgtttctaaa agatcttcta cataagacat
     7561 atattcttcg tcttcacgcc atttttctgt cataattatc gatctgccac ctttttgaat
     7621 ttcattttct tctgaaattg atctaagtat accaccagtg ttcggattat tctagtcgcc
     7681 ttggataaaa tagccaaagc ttaatagttc cttaatcata aagaaaaatg ataaagaaca
     7741 atccctgccg caaccccaac attcaacgat tccgcatttc ctttcatcgg gatatatacg
     7801 ttctgatcag tcaaagacaa gatttcctga cttaccccct gaccttcgtt ccccatgatt
     7861 attgcgaagt tatctgattt ttctactttg tctaatgcgt gtgcttcttc atttaattct
     7921 gtgccataca ctgtaaaccc tttgtctttc attaaagaaa tcacttctgt caaatctttt
     7981 tgcaacacag gcaaatgata attgcttccc tgcatgctgc gcagcacctt tgtactataa
     8041 atatctgccg ttcctttgcc taataaaaca ccagccatat caaatgcatc tgccgtacgg
     8101 atcatcgtcc ctacatttcc aggatcttgt acattatcta acaacagcca tcctcctgaa
     8161 aaatctggcg tgccttcagc cgttaacgcc atcactgcta agattccttg tggtgtaggt
     8221 agatccgata cagcatccat gacctcatcc gaaactagaa aagtagaaat ctctttgttt
     8281 gcggccagcc agtctcccca ttctttcatg cctcgctgtg tcacaaaaag ttcttttatt
     8341 tctgcatcag acgacgcagc ttcttcaatc agatggaacc cttccaaaag atattcttcc
     8401 ttttcttccc gatatttctt tttatgtagt ttttttaatt ctttgattct tggatttttt
     8461 gctgattgga tctctttcac attcctcacc tccccatgat tatatcatgg aataggtgct
     8521 tgagcttgtt tcatcctaaa aaaatcggta tcattaattt ataaaatagg aaagaaaggt
     8581 gacgaacatg cgcaaagtta aaatgaacgt ccaaggacgc gtccaaggcg taggatttcg
     8641 ctatatgacc aagatggtcg ctgatcaact aggcgtgact ggaacggtaa aaaacgaaga
     8701 tgacggctca gtcacgatcg aagcaatcgg caatgacgac atcatccaga aatttattga
     8761 agaagtcaag aaatctccga gcccaagtgg acgagtgcag tatgtggatg tccaagaaga
     8821 cccgatgatt gaggaacgaa agaaatttga tgtggtggga taaggttgtg aaaaagctgg
     8881 tctgcatcaa gcattaagga caggttgtga aaaatagctc tccatatttt tcaacaggct
     8941 ggacttaatg ccgtagatgc aagcttttga acaccgtcga taaggttatt cttgaggcgc
     9001 tttgcctcaa aaattaagga cagcagtgaa aaagctgatc tatcacttgc agtgagttca
     9061 tttgactccg ctttttcggg cagaaaaaaa gtttttagtt tattaaagta agaaagaaac
     9121 acttggaatc attctacttt ttcctagtat ttctttcttg attttttgtc tttttttcaa
     9181 aatttttcgc tacgtaaaag aacgaatatt tatatgaaat ttctatgaag ttgattgaat
     9241 tccatgcgct tttttagtat agttaagttt gtgtaaaaat tatagaagag gaagtattct
     9301 atgaataaat ggaaaaactg gttattggga tccggacttg tcagtatcct gctcttttta
     9361 tctggctgtg tgcggatgga ttcaaacgga aaccctgaca cttcgggaat cgtttatcga
     9421 gtactcgtcc atcctatggg ccaagcgatt acatatctag ttgaaaattt caattggtct
     9481 tatggctggg cagttattgc aatgactgtg atcgtccgta tcatcatctt gccactaggt
     9541 attagtcaat cgaaaaaaac aatgatccaa tctgaaaaaa tgcaagcgtt aaaaccacaa
     9601 gttgaagcag cccaacaaaa attgaaagct gcaacaacac gtgaagaaca aatggcagca
     9661 caagcagaaa tgcagcaagt ataccgcgaa aacggattga gtatgaccgg cggaatcggc
     9721 tgtctgcctc tattgatcca aatgccgatc ttctctgcct tgtactttac ggcacgttat
     9781 acagaaggta tccgggaatc atctttctac ggcatcgatt taggctcacc aagtatggta
     9841 cttgttgcca ttgcaggggt cgcttatctg cttcaaggat acatctcaac gatcggtatt
     9901 cctgaagaac agaaaaagac gatgcgtacg atgctgatcg tctctcctgc tatgatcgtc
     9961 ttcatgtcga tcagtgcgcc agccggtgtt acactttact gggtagtcgg tggtgtgttc
    10021 agctgtctgc aaacattcat cacaaacgtt atgatgaaac cacgtttgaa agcacaagtg
    10081 gcagaagagt tgaaacaaaa cccaccaaaa caagtcgtca ctccaagaat tgatgtgaca
    10141 gaatcagcta aaccagctga cagcaaacaa gcaaccaaac aaatcaagca acccaaaaac
    10201 agtacaaaca ataaaggccg caacgcagga aagcagcaga agcggaagta gatagtaaat
    10261 aagagtgtaa taaaaattca ttaacagttt tagcaattaa aaatatcgac caagattttt
    10321 gaaaaagaaa tctggtcgat atttttattt aagtgaatgt ttaatttgaa tcatcgattg
    10381 atcgctatct aattgcagca gcatcttttt atgaagaaac aactttttct tatctatcaa
    10441 cgtagacagg tgttgctgtt tcttctaata gtgtacttaa ttccttaata ttttgttttc
    10501 cttcttctaa catccaacta ctcgcttttt cttcgccttc ggtaacaaaa ggcgccactc
    10561 ccttcgccca tgttgctcgc ccacataaga caccattctc cataaaggac aacgcggaga
    10621 taccacccat ctaaataaca tccataaacc tttctagtag aagaatagtg atagtatcca
    10681 tccctttttc tactgggaat acaattacac gattcaaagc ttgatacaca acatttccct
    10741 tcttataaac cgctattgta accgaattgt tttgaatcac ctttttggga tagaaactgg
    10801 ctcctttccg caacttctta aatgttggtt tcttttatac tttctttgta gcaactacaa
    10861 atttcttcaa atctctaaat gtttgcataa caaccgcctt tctgactttt actcaggatg
    10921 gtatttaaaa atcagcaaaa taaggcttct ctccatcttt tttatttcct agctgcttta
    10981 aagacactct tgctgttttt taatctctat caagggggct ctgaatctat tttgatgaac
    11041 ttatcttatt aatttctcaa atgagctgtc agacacaact gtattttttc aatctcatac
    11101 cggacaacta tgccagctta aaaaaatttc ctctggcaaa acttctttat tgaaaaatga
    11161 caatgaaaaa agaccattct ttttgttgaa tgctcattgt gtaaacatat ttcctgcgac
    11221 tgctcttcga accattctca gtgcaatccc taatttatct attaaatctt cttttagttc
    11281 ctcatctttc atattcaaaa tttcctttgt atgttacaca agtttgttct ctaaata
//
LOCUS       DBBGRF010000081        11319 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000081 DBBGRF010000000
VERSION     DBBGRF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.081"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            142..747
                     /gene="fic"
                     /locus_tag="ACIZD4_002657"
     CDS             142..747
                     /gene="fic"
                     /locus_tag="ACIZD4_002657"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HGC5991519.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            763..1335
                     /locus_tag="ACIZD4_002658"
     CDS             763..1335
                     /locus_tag="ACIZD4_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5991520.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1587..1844)
                     /locus_tag="ACIZD4_002659"
     CDS             complement(1587..1844)
                     /locus_tag="ACIZD4_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991521.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1970..2785)
                     /locus_tag="ACIZD4_002660"
     CDS             complement(1970..2785)
                     /locus_tag="ACIZD4_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991522.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            3302..4627
                     /locus_tag="ACIZD4_002661"
     CDS             3302..4627
                     /locus_tag="ACIZD4_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HGC5991523.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            4620..4970
                     /locus_tag="ACIZD4_002662"
     CDS             4620..4970
                     /locus_tag="ACIZD4_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991524.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            4967..5137
                     /locus_tag="ACIZD4_002663"
     CDS             4967..5137
                     /locus_tag="ACIZD4_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991525.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
     gene            complement(6041..6316)
                     /gene="prgO"
                     /locus_tag="ACIZD4_002664"
     CDS             complement(6041..6316)
                     /gene="prgO"
                     /locus_tag="ACIZD4_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HGC5991526.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(6288..7241)
                     /locus_tag="ACIZD4_002665"
     CDS             complement(6288..7241)
                     /locus_tag="ACIZD4_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5991527.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            7853..9346
                     /locus_tag="ACIZD4_002666"
     CDS             7853..9346
                     /locus_tag="ACIZD4_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HGC5991528.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            9481..9777
                     /locus_tag="ACIZD4_002667"
     CDS             9481..9777
                     /locus_tag="ACIZD4_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HGC5991529.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            9878..10729
                     /locus_tag="ACIZD4_002668"
     CDS             9878..10729
                     /locus_tag="ACIZD4_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991530.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            10750..10962
                     /locus_tag="ACIZD4_002669"
     CDS             10750..10962
                     /locus_tag="ACIZD4_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991531.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         3906 a         1756 c         2092 g         3565 t
ORIGIN      
        1 ctagactgtg caaaatagag acacttgaaa aatctatcgg gggtcagaaa cttaatagtt
       61 tttgacacat aaacaaaatc gcgatataat ggggttgaga gtgtttcata aacttatgtc
      121 ataaagttaa ggagatttcg catgatttta gagaataaat tgggattaac caatcaagtt
      181 gagttggcta aggttgaaga aaaactcagt aaacaaaaag cgaaagaatt gtacgattgt
      241 ggaaaaataa atgaaatcga agttggtaca tttaaaggtt tatctgaaat tcatgaattt
      301 ctattttcgg atatttacga ttttgccgga aaaatccgat cggtcaatat tgcaaaagga
      361 aattttcgat ttgcaccagt tatgtattta gaacattcgt tacagcatat tgatcagatg
      421 ccacaaactt cttttgaaga gattatcaag aaatatgtgg agatgaatat cgctcaccca
      481 tttcgagaag gaaatggccg aagtactaga atttggctgg atctcatttt aaaggaagaa
      541 ttgcaaaaag ttgtagattg gaacttaatc gataaagcag actatctttc tgcaatggag
      601 cgaagtccca taaacgattt ggaaatacgc tatctaattt ccaatgctct gactgataaa
      661 attgacgatc gcgagttata tatgaaagga atcgatgtca gctatttcta tgaagggtat
      721 tctgagtata cgatagatga tttgtaaaag taggtggacc aaatgacgaa atatggatat
      781 gcacgtgtct caaccgcttc tcaaagtaca aaagaacaaa ttcaacagtt gcttgagaac
      841 ggcgtagaga agaagaatat tttttcagaa aaatttacgg gtacaaaacg ggatcggcca
      901 aaattcaatc agctgttggc tggtctgaag cctggagatg aaatagttgt tacgaagctt
      961 gatcgatttg ctcgtaacac gagagaagca ttagagatca ttgaaccttt actcgatgat
     1021 aacgtaacga tcaaggtttt gaatctagga acgattgaaa atacgtccat ggggcgaatg
     1081 gtgacacgga cgttgttgag tgtagcagaa atggaacgtg atatgattgt ggaacgtacc
     1141 caagaaggaa aaatgtttgc aagaaagaat aatcctaatt tcagagaagg acgtccgaaa
     1201 gcaacaatca caccgaagaa gaggcacgca tatgaactgc ttacttcagg taaatcgtat
     1261 aaggaagttg aagctataac cggtttcagt cgcagtacgc tttttagaat aaagaagaaa
     1321 attgaagaaa gttaaaaaag aagtctcagc gaaccagaca ggtaaatact taatgcgttc
     1381 tagatatgag tctattagca tgttgtgaaa tataatattt ttttatttac ttgatttctg
     1441 ctcaaaaaat gtgtatggta actgtaaaag gtaaagtaat taaaggtatg ctagccacgc
     1501 ttactatatt aggataccat catatattta taatgaacga tttgttcgtc taccaaacaa
     1561 cacatatcgt tcagcgtaag tcacgtttag gaacgtggct tttttagtgt tattatcgat
     1621 aaataatcta ttgactctat tgattttatc tccatatccc tacggtgttg attgtcttta
     1681 gatctttcat ttaagaacca aataactatc ataaaaatca gcactgctgc taatataata
     1741 aacagcattc ctattgtgat attacctatt gattttacca taactacgat taaagtaata
     1801 atggcattca agtctccttt gttctctata tataaattag ccataaatca tcttcctttc
     1861 aaattaagat acttgtttga taccaataaa tagtaagcgt ggctagcata cctttttctg
     1921 taatagcaag tgttctaata gtccaaactt aatgatggac cgatgctagt tatagtacag
     1981 taatgttttc tttcttatct agatttttag taagctctat cagcaaatct aacaaatctg
     2041 agtccttttc agaaactaaa ttaaatctag tgtttacaac aaagttttca tgttctatat
     2101 tgtttagatt atttgcggaa aggagggctt ctagatcttg acattcaaat ctatatgcat
     2161 cgtcataaat cttactagaa ggagtgctta attcgaaatt acttattttc tcatcttgga
     2221 ccaagataaa tttatagata gtatcttttt gtgtttttct tttaaaaaca caacagagtg
     2281 tgttataagg aacgttataa ttttcatcag cctcattttt tctccattca aacaaatgat
     2341 aaactgcaac caagttgcca tcaatttcat ggacagtgct ctcggtaaca tcctttaaag
     2401 aactatcaag ggctaattta tagtaactag agagaggaag taaaattgtc gatttactga
     2461 gatggttatc gtctatacgt gcaatcatac ctaaatcaac taaggtttta ttccaggtgt
     2521 ttatagtttt agttgtcact cctagagact ctgctatggt attgaccgaa tgccaggaat
     2581 ccccgccttc attctttgcc ttaaaacagt aatacagata taaattaata gctttgttat
     2641 tcggtaaata tttttcaagt tctgttggta gaataaagta agaatcctta atgttttttc
     2701 tgaactgtct ccagtctctg tagttttgtt tataaagttg tgaaacggtt tttccacctt
     2761 tagaaagtcc tgctatctta accaatctta ttgctccttt cttgaatctg tcatgatcat
     2821 acagtatttt ttacttgtag tccagcacct taatatatta tcctatgtaa ttaatttcgt
     2881 actagatagt aattattttt tatttaattc tctagtcact tacaaataag ttatataaac
     2941 tacgattaat aaattattac aaaaactatt aagaaaactt ctacatacaa ctattacaaa
     3001 actattaaga aactgaatac tcctattttt tgtttttaag gaaagttttt tcttttttga
     3061 atttcttatt tttttctaat ataactaagc aaaactggat aatacgacac ttattttcaa
     3121 attttcacaa gactaatagt aaatatccat ttaataaagt gatacaatgt gttgatttta
     3181 caaatcaaca gaagaagtag ggaaataact tacctatgct tctttttttg tacatttaat
     3241 cgattcttct ttacaaaaac gaacgtatgt ttgtataatg tggaagaatg gagtgttatt
     3301 tatgatggat tattcaaaag agccagtaaa tgattacttt ttgatcgata tgaaaagctt
     3361 ttacgcaagt gtcgaatgta tagaaaggaa tttagatcca ttaacgactg aattagtcgt
     3421 catgagtcga gcggataata caggatcagg gttgatttta gcttcttcac cagctgcaaa
     3481 gaagaagtac ggtatttcta atgtcagtcg accacgagat ctaccgcaac cttttcctaa
     3541 aacgttacat gtcgttccac cacgcatgaa tctctatatt aagcgaaata tgcaggtaaa
     3601 caatattttc agaaggtatg tagcagacga agatttattg atttactcga tcgatgaatc
     3661 gatcttaaaa gtgaccagat caatgaatct ttttacgact gaaggaacaa gaagtcaacg
     3721 gagaaagaag ctggctcaaa tgatccagga gaatattaaa gaagagctag gattgcttgc
     3781 tacagtaggt gtcggagata atcccttatt agctaaactt gctttagaca atgaagcaaa
     3841 acataatgat ggattccttg ctgaatggac gtatcaaaat gttcctgata aagtatggaa
     3901 tattcctgaa atgacagacc tttggggtat tggatctcga atgaaaaaaa gactcaacca
     3961 aattggtatc atgagtatta aagacttagc taattggaat ccatacacta ttaagagcca
     4021 tttaggtgtg attggcttac agctgtattt tcatgcgaac gggatcgatc gaacagatat
     4081 agcgatccca ccagaaccga caaaggaaaa atcatatggt aattcacaag tgttaccacg
     4141 agattatacc aggagaaatg aaatcgaact ggtggtaaaa gaaatggcgg aacaagtagc
     4201 tattcgtatc aggcaacata actgtaaaac aggttgtgtc catttataca ttggcacgtc
     4261 gatcttagaa acgagaccag gtttttcaca ccagatgaag atccctataa cagataatac
     4321 aaaggaattg cagaattact gtcttttctt gtttgataag tattatgaag gacaagaagt
     4381 aaggcacgtt ggaataacct atagcaagct tgtgtacact gattcgcttc agctggattt
     4441 atttagtgat ccacaaaagc aaattgacga agaaaattta gataaaatta ttgacaagat
     4501 tcggcaaaaa tatggtttta cgtcgattgt acatgcttct tctatgttag aaggcgctcg
     4561 tagtattact agaagtacat tggttggtgg ccatgcaggc ggcgcaggag ggcttaaaaa
     4621 tgattgatta taatgatcgt ggacgtttaa agtgggcagg tttttattta tctgatcata
     4681 ctgaaaaaat tgatgccgac aatgaacaac gagccaatca aaatttggca aaagaacaaa
     4741 tgacgactga agaggttgcg gaagtattga acgctgcagt cataaaaaat agatcagtat
     4801 gtattcaaaa agaagaacga aacgctgaag gatactatcc agaagatatt gttagcaaga
     4861 tcttaggtag tgatgagctg gggatctacg ttggaaaaaa caaagttcac tacgacgaaa
     4921 tacgtcatat cgaattttac caggataata aatggggtcg attagaatga acattatcca
     4981 gcaatatgag ctaaagtata taacctttga tcagctatca gaagagattt ggggttatgg
     5041 ccagcgtttg ataaatgagg ttggtgttga acgcttctct ttctatgtag aagctgcagc
     5101 aggataccat aaatacgaat actatattgg ctattaaagt gcaataaaat tatatttctt
     5161 ttatgtttta cattttgtat caattctgat aaaattacct ataggtaatt aaaaaatata
     5221 aaaaaactag ttacaacctt aggacgttgt aactagcttg aagcatacta gagctaacta
     5281 aaatagcact agaaagcaat gttaaacccg tccaacaaac ttgatttaac attgagacca
     5341 gcttattcag ctaaatatag ttgaataagc ttcttttgtt ttaaaaaaac aaaaggtgta
     5401 ctacgaataa cgcaagtaaa agaaatacta ttacaaccag taggctacaa gtaagtatta
     5461 ctaaacattg cgtagttaga acctttgctc tattgtctaa agccacaaaa ttagagatca
     5521 gctttatgat gctaagagcg agctgcatcc atgcggacat aggttctttt gacactatta
     5581 attctccttt ttaggataag ggaaattgct agtagttttt tcattagcac catccccctt
     5641 catttgattg agtctagtgc tgctgtgata gtttgctgtt taatatgctt acattcttat
     5701 tataacataa atgaaacaaa cacatggtta gaggtcgtat caatcaaaat agtgtctcac
     5761 aaacgattta ttacttactc ctgctgacta acggactgtt cttcagtaac tgtaactata
     5821 tgtttgttaa aaccaccatt acctgtagat aaaaaccaat atatttacta tactcactat
     5881 attaaatata tttagtatag taaaaactag aaacaataaa atttgtgaat gttgtatacc
     5941 cccaaacaat acacatattt tgaaggatta ggattaataa agctaaaaat atagtaagta
     6001 tactaaatat atttactata tctagtatac ttactatatt ttaatctttt gatcgtctat
     6061 tatatataat ccgttcctcg tcgtttaaag tatcaacata ggcgtccatt gcaagtttga
     6121 ctatttcata cataggaata tcttttgcat aactaagatc ccgaatggtt tttagtacgg
     6181 gaggatctac ttgaactggt tttctttctt tcgcagtgta ctttcgttcc cctaactcga
     6241 cattaatatc atctttaatt gaaatatctt cagcaccaat tttcttctta tctttgttcg
     6301 ttggtaataa tgccatttag tttaatctcc tttccaagag gtaggatatg attggccatt
     6361 gagtcagcat atttaggtgt ataatcaaat ccttcaatat caccatgttg ttcatagtat
     6421 tcaattcttt cttctaattc tgtaaagatg tctgcaaaaa tagcccacca tcttcgatct
     6481 acataatcat ttaattggat accattctca ccatacattt ctaaccgatc cgagccttta
     6541 acaatgcttt taaaaatgtt tgattcacca tacttatcaa ttgttttttg atagtttgcg
     6601 tgttgagagg aacgtcgcac tgagaaaaga acaggcaaaa ttccaatgat ttgaagatga
     6661 gactcttcaa aattcgtgac aatcggaact aaaactttat taataaaatc ttctgttcct
     6721 tccattgcgt accgttttaa ttcttgcatt gcaataatat aatctgcagc agttaagaat
     6781 gcacgaacca cattatctgt tgatggtggg cagtcgataa agatataatc gaaatttttt
     6841 ctcaattctt ctaaaggttt aatgaaggcc aatgatctct tacgacgatc aggatatttt
     6901 tcggacaagt attcattaag ttcttcagat ccaggagagc cagccataat atataaatgt
     6961 ggacttactt gagtaatacc tgaaacccag tccccttttt tgattgctgc agacatggat
     7021 cgatcaaagc tagtaatttg atacgttgat ccaatgttgg aagtagtatt tctttgttgg
     7081 tcataatcaa ttagcaacac gtctttttca aaaagttgac tagaaacaat cgctaataaa
     7141 tcattgtctg tagtcttacc aatgccgcct tttctacctg taagcattac aacttttcct
     7201 agtttatctg atgttttaaa tgcagtccgt aagttttcca tagttccctc caatttccta
     7261 tactaaatat atttagtata cttcatatac ttaatatatt cgatatatct aatatactcc
     7321 aaattgataa gaattcagac tttataagga atatagtgga tatactaaat atatttgcta
     7381 tattcagtat atcagatata ttcaaaatgt caaaatatat ttgtgcgttt tgcgttgaca
     7441 atttagagtg aaaagaggta aacttaattc tatagaaacc acagataatt cactatttac
     7501 aaagtagcaa aagcagtggt actctttaaa cagaaaaatt acataaaaaa aagagacgga
     7561 aataattgat tttagcagaa tcaattattt ctgaatcaca tggttaggac atgtgttcac
     7621 gctcgtctca agaatatgta agtagctacc aactacttat attaaaagtt gatcggatac
     7681 cttttccgat tgcctttatt ctaccaaaaa aaggcgagca actcaacaga agaacgttta
     7741 tttagtgtac ttaaattaaa tattcttaaa cactgaagag agaacacata ctatggctga
     7801 gattaaagct aaactgtgtt ctctttttgt ttgagaaagg acgttacaat cgatgttgag
     7861 cgaaatttat tcagctattc ttaaaaacgg cttacgtaca tacaaatatc gaaacagcac
     7921 catgaaacct gcaggtcata ttgattccag taggagtggt gctatctttg cgtaccgtag
     7981 caagcaatta atgaatgttg ggcgtggtat ggtcattact tcggaagaag ctattttaga
     8041 gaacgaaaag aaactaacgc attggacacc taatacctat cgctttggta cttatgcgga
     8101 tgattatcga acagtggtta aaggtcattc tgagaaaaac ttaagtcaaa tcaacacatt
     8161 tgtagttgat atcgattcaa aagagaacca tcaaggcgaa attattttag cctgtttaga
     8221 tcaagtgggc tacatgccaa cgctaatttt agaatcagat catggttatc aagtttattt
     8281 tgtactaaag acaccaggct atgtcacaaa gaaaagcaat ttcaaggtga tcgatgtagc
     8341 aaaaaaaatt tcaaaaacaa ttcgtctaca gttggctgaa aaattgtccg gagtggatct
     8401 aggatgtaac cacttcggaa ttgctcgatt cccacaagaa aataatattg tttttaaaga
     8461 aatgaactat cagtattctt ttgctgactg gattcaatgg tcgatgaagc ttgaatcaga
     8521 tcaaaaaaca aaagaagatc gagaacgaaa actaattgtc tttcctgaga aaaaagaaat
     8581 tcgtcaagta gatgaaccgt ggttcgatat gttacttcat aaagcaaaca tcgtcggcgg
     8641 agaaggacgt cttggtcgaa ataatgtgat tttcacgctt tctttagctt attactcttc
     8701 aggttatgca ttggatactt gcgaatacaa tatgttcaca ttcaacgaac ggttacagga
     8761 accgctatct gaagcagaat tagtaaagat tgtacgtagt gcttattctg gtaattatca
     8821 agcagcaagc agagaattca ttattgaatt gtgccagcaa tgggtttcac caaccttaaa
     8881 aaataatgat ctgttcattc aacgacgtgg ctggtggaaa tttaaaaagc cacgagatca
     8941 aagaaaatat agtcataaaa atgaatggaa agaagatcta ttggcttatc taagcgaaaa
     9001 aagtcttgct agtgagcctt atttgaacct gtcaaaaaaa gaattggctt cacaactaac
     9061 gatgcccaag cgaacacttg ataagatctt aaatgagtta cgagaggaga ataaagtctt
     9121 ctacaaggta acacgaggaa gaaatggcgg aatgatcatt gcttcagtca aaacgttgtt
     9181 cgcgagggtt attcaactaa gtaaagaaaa gagactagat tattcaacaa ggatcacaga
     9241 ggtatttgga ctcaacgaga gcttagtaga agagacattt agacaattat caaccccctt
     9301 gaaccctctt aaagaagtga atctttttga agtagataca ggttgaaaaa taaaaggtgc
     9361 aaattgccct atacaatata tctatgatac ttctgtaggt gttgctccct ttgcctagct
     9421 acgtgtaggt ggtatactta taactgcgta tgcagtctta tgtatcatgg aggaagttgt
     9481 atgtcgttaa aaaattatgt ctattcacat cctgttaatg tgtttatcat tggtcgtttg
     9541 ggattatctg tggaagtgtt ctgtgagctt tatggtttta agcaggggac tttgtcttct
     9601 tgggttacca gggaaaaaac agttgcttct ttgccgattg agtttcttca tgggttgtcc
     9661 ttagcttctg gggagactat ggatcaggta tatgattgtt tgtgtgtgtt agagcaggag
     9721 tatattgagt ataaaatagc taacgagtta agaaaaagga agaagtatat ccagtagtag
     9781 tttttattta cttaaaaaat tggttcattg agcaacctat cgctgctaaa gtagcaaagg
     9841 aaaacgttaa aggaaagaat ttagggaaga aatcgaaatg aaatcggacg actggattga
     9901 acacacctgg cttcctctga aaagaaatag caaacgaaag aaattttggg tattgcaatt
     9961 atggccatta ggaaaacttt gtagttacgg ggcacgactt attcttgatt taaccgttta
    10021 ctcgattgga gtatttggaa cggcttatta cttgataaat gatcccaata ggattgcagc
    10081 atcagacatt tttacagtgc taatgacgtt gatttttgtc atgctattgt ctatttttac
    10141 tcaattagtc atgcaattta ccaggcaaaa attaacagca ggaaaacttt tcaaaagcct
    10201 attcgattta attgttgtaa atgcaattct agcgacttta ataaaacaaa ttgaacaatc
    10261 tggaagaaca acaaaaggag tgaaggattt tttattgacg tttattcact ttgtaaatgg
    10321 acacatgtat ttgtttgaag tgggtattat tctctttttt gtcgggtatg tatccacgaa
    10381 acttattaaa cgttcaattg aaaaagaaat tgaaattgac ctgattccga cacttcttgg
    10441 ttatgagtac aatgttgatt ttggaagata tgacgaattg atcaatacgg atatcgttca
    10501 cacgagtatc catgaatcta ctgttaaggg catcagatct attttaaaaa atggccagga
    10561 aatgaaagca atagatcgaa gaaaagagat ctacaatttt tatgaagtcg aagcaagcct
    10621 acgatatggc atcggaaaat tgtggttaga tggaagtaat attcgtcaaa acaaaccata
    10681 cattttttgg aacagtagtg atttagaact tccaatgaaa gataaataat tatggagaat
    10741 cgtttgaaaa tgattcctct atacaggatt gtgcttatag ttggcatgga gttaaaaacc
    10801 ttaaagaagg agcagttatt caaagtgaaa gaacgtcata atcagttact atgtagtaaa
    10861 acgggtacga tgaacattga ataccgaaca gaatatttag aattaacgaa tcaaactgat
    10921 tttttgttga ttcgaaagca acaagagcaa gaaaaaaatt aatggctact tatagccaat
    10981 tgattgatga atgggaacaa ttcaaggaat ctaaaattcc agaacgtctc taaaagcctt
    11041 tatttgtaaa gagcataagg aaacgtggga acacttttta aaaaaagtgt tccaataggc
    11101 tgtgcctatt acgtttctca aaaataaatg tgggaacaaa atatttaaaa ataggatagt
    11161 gaaaggatag tgaaggatag taaaaggagg gtagtaggat agcaaaaagg ataggctcct
    11221 tttcgctatc ctttttaaat tggaggaatt aatatggaag taagaataag aaatgtggat
    11281 gagaaaatcg taagagaaat tgatcgaaga tgtgacgaa
//
LOCUS       DBBGRF010000082        11196 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000082 DBBGRF010000000
VERSION     DBBGRF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.082"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            148..1551
                     /locus_tag="ACIZD4_002670"
     CDS             148..1551
                     /locus_tag="ACIZD4_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC5991532.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            1900..2532
                     /locus_tag="ACIZD4_002671"
     CDS             1900..2532
                     /locus_tag="ACIZD4_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HGC5991533.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            3120..4559
                     /locus_tag="ACIZD4_002672"
     CDS             3120..4559
                     /locus_tag="ACIZD4_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5991534.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4854..5072
                     /locus_tag="ACIZD4_002673"
                     /pseudo
     CDS             4854..5072
                     /locus_tag="ACIZD4_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            5321..5536
                     /locus_tag="ACIZD4_002674"
     CDS             5321..5536
                     /locus_tag="ACIZD4_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991535.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5753..6009)
                     /locus_tag="ACIZD4_002675"
                     /pseudo
     CDS             complement(5753..6009)
                     /locus_tag="ACIZD4_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6196..7107)
                     /locus_tag="ACIZD4_002676"
     CDS             complement(6196..7107)
                     /locus_tag="ACIZD4_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC5991536.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(7126..8130)
                     /locus_tag="ACIZD4_002677"
     CDS             complement(7126..8130)
                     /locus_tag="ACIZD4_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HGC5991537.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(8127..10250)
                     /locus_tag="ACIZD4_002678"
     CDS             complement(8127..10250)
                     /locus_tag="ACIZD4_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HGC5991538.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10255..>11196)
                     /locus_tag="ACIZD4_002679"
     CDS             complement(10255..>11196)
                     /locus_tag="ACIZD4_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5991539.1"
                     /translation="RGGWKETLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSES
                     LAIDILTFLTGISSRDGEKFPVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIAD
                     HIESFTDYDFAHLLFSDGSITQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSV
                     SMLIVISTFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYF
                     VTQNSDDLLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQ
                     CLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         3471 a         2106 c         2084 g         3535 t
ORIGIN      
        1 ttaaaggcag taacaggatt aaacattgaa acataatcgt tactaaatga aatcaagaaa
       61 tatactgtat tactcaattc attgaaaata tttatcataa tttttaatag aaaacactat
      121 taaagagaaa aaagagaggt aaatcaaatg aaaaaatctt taaaacttgc atcagcagtt
      181 atattaatgt cccaactcct tatagcaaca cctttccatg tgttggcaag cgaaaattca
      241 acatacaaaa ttgcaaaaga aagaaccgag acgactgaaa tgagtaattc cgatgtaaca
      301 gcagagagta gtgaactttt gacaacttca tcaagtgaaa gtagtacgac ttcaaatgcc
      361 gagtcttcaa caacttcatc aagtgaaagt agtacgactt caaatgccga gtcttcaaca
      421 acttcgtcaa gtgaaagtag tacgatttca agtaccgaat cttcaacaac ttcaagtagt
      481 acaagtgaaa taacttcttc gaaagtgaca aaaccaaacc atatagaatc ttcaaaaaag
      541 gaagcgccaa aaacggaagg acaaacaaaa actttttcga caccacagca aatagaatca
      601 acagaatctt tccaatcaca accaatacta tctggtaatg aagaaattca ttttgacaaa
      661 aatgaatctg tagaaaattt tattatgaaa attggtgagt ctgcgagaaa aattggtcag
      721 aaatatgatt tatatgcttc tgttatgatt gcacaagcga tcttagaatc tgccagtggt
      781 caaagccagt tagctcaggc accgaattac aatttatttg ggataaaagg aacttataat
      841 ggaaactttg tcattatggt aacaaacgaa gatttgggta atggaacgct ttatacgacc
      901 caatcaaaat ttagagtgta tgaaaactat gaggaaagct ttgaagatta tgccaaatta
      961 ttaactaagg gaattagtgg aaataaagat ttttatgcag gagcattaaa agctaatagt
     1021 aaaacatatc gagaagcaac taaattcctt acaggacggt atgcaacaga tacacaatac
     1081 tatttgaagc taaatgaatt aattaaaacc tacgatttaa ccaactatga taaagaagtt
     1141 aaaggtccac aaatgagtaa gactggatac caagtgccta ttcataatta ttcaataacc
     1201 agtttgtttg gaaatcgtgg aaatgaattt caccgaggac ttgatatggc agctacacag
     1261 ggtgagccga ttcatgcagt taaagctggt aaggttgtta aagcagagtt tcactactct
     1321 tggggaaatt acgtggtgat acaacacgaa gatggatcaa ccgcgttata tgctcaccag
     1381 caacaatacc tagtaaaaac tggagataat gttttgcaag gacaaataat tggctatgta
     1441 ggaagtactg ggaatagtac tggcccacac cttcatttgg aaatttgcaa agatagtagt
     1501 ctttctcaga gcatgttagt tgatccgaaa accttattat tcggagacta aaaaaggtaa
     1561 tcaatctgac aaagtaacaa gaaaatggtt ggattcttag acctttgatc aggatattga
     1621 gactggaatt gatatctcga ttacgatggg tttgacaaat aaaacaagtc cattatcgaa
     1681 tatcgagtgt attattgccg tctttatgct catattttga gcaggtttca ctagatgaaa
     1741 acaatttatc tatcttgagg atttcgtgta cgtatcgttc agtcttgtat tgtaaattag
     1801 tcataaaatc agactaagaa aaattggaaa tatttttttc tgatttatta aaagttaatt
     1861 gaaattatat ggtacttctt tcttgggagg gtaggtgcag tgaaggaaag atatggtcac
     1921 cttactgttg ttgaggagat tactcataat ggatataaaa aatatcgttg cctatgtgac
     1981 tgtgggaatg aaacgattgt atatcgatca aacttactaa caggtagaac caaaagttgt
     2041 ggatgtggaa attataaaaa taggcataaa tataaaaatt tgacaaataa aacttttggt
     2101 aagttagttg caatcaagcc aactaaactg cgaagtgaag gaactgttgt ttgggaatgt
     2161 caatgtctgt gtgggagaaa aaagttagta tcggcaaagc gacttctaaa aggtgatgta
     2221 aaaagctgtg gatgtttgaa atcaaaaaag catcacattg aaaataaaaa attcggatta
     2281 cttactgcaa agtatccttt ggacaataac tgttcatgga aaacaaaatg ggtttgtcat
     2341 tgtgagtgtg gcagtatgtg tgagataagt tatagtaact tattttttgg acatactcaa
     2401 agttgtggat gtttaaaaag gcaagaaaca aggacatgtg ttgaagggac agtaatagag
     2461 tgtctaacgt caaaattacc gaaaaataat acaagtggtg ttaagggagt ttatcgttct
     2521 aaagagaaat agattgcgta tataacttta aaaaaaaaga ggtactattt aggatcgtat
     2581 gattctatta agagtgcagc tcaagctaga aaagatgctg aaaataaatt gtttcaacct
     2641 ttgattgaca aatatcgagg taatcattaa ttattgtgga taataattaa cagtgatata
     2701 taaacatcta taatatatta ttcatactat tgatatttag tataatccta tggaattgaa
     2761 tatcatagca atgtatttga aaagcaaatt ggaaaacaaa taggtgcaac accataaata
     2821 tgaaaaaatt gggaaaaagt agaatggaaa tttgcttacg tctcacgaga tagctcacac
     2881 tattaatctg aagaacaatg aagtcgactt ttagaaattg ctagaagaaa gtaaagcgaa
     2941 ttatcactag ttactataga gtaagttcaa ataaagcatc tccaacttac atggttacat
     3001 gaggatatca aatcgaaatt actcaagctt cctatggcta gagtcgcgag aagttgttgg
     3061 gcagtagaca taggttatat tgttcttagc tacacgatca ttagaaagga aatcctatta
     3121 tgtatagtta tcaagaagat gcaaaagtcc aaaaaaatcg ctggtggatt ttgattgcta
     3181 tatctatgtt taccttcatg tccacattgg atggcagtat tgtcaatatt gcactaccta
     3241 ccatctcaga tgatatgggc ataccaatga atcaagcgga atgggtagtg tccgtttatc
     3301 tgatgattgt ctgttcttgt ttgttgctgt ttggtaaaat tggcgatagc cgtgggaaaa
     3361 tcaaagtatt tcggattggt acgctgatct ttgtcttggg atcgctgttg tgtgggttca
     3421 atcattcgct aggtatttta ttgttcgcac gggtggtaca agccattggt gctagtatga
     3481 ctatggctac aaatgccgga atcatcacgg aagtctttcc catacatgaa cgtggtcggg
     3541 cattgggagc aataggtgcg tttgtttcat taggctcgat tgctggacca ggtcttggcg
     3601 gcttgatttt gtcccaattt tcttgggcgt acattttttg gatcaatgta ccggtgggaa
     3661 tcgtaacgat gttgattgct gaaaaattct taccaaaaga tatcaccatg agcggccata
     3721 caatcgatgg agggggcttt gctgccattg cggctacgat tatcagcttt tttggagcaa
     3781 tctttttggg gcaagaaagt ggctttttcc atccagtccc ccttgtactg ttcgtaattt
     3841 cagtgattgc ctttgtcagc tttttaaaag ttgaaaagaa agcagcctct ccattgattt
     3901 ctttcggtat ttttaagaac aagattttta ccatgagctt gattacagcc ttgttgattt
     3961 tttcttccaa cttctttgtc aatgtagtga ttccttttta tctgcaaaat gctcgcgggt
     4021 tgagtcctag ctatgctggg ctgttgatga tggtctttcc tttgatgatg gtcgtcgggg
     4081 cgcctttaag cggctacctg accgaccggg ttggcccgga gattttggta ttagtaggct
     4141 tgggcttatt gtcggtaacc caggtcatgt atatgttttt gtcagtggac tctcctttgt
     4201 ggctatacat tgtcgctact gccatcatgg gtgccggcaa tgccttgttc cagtccccca
     4261 ataatacgat ggttatgagc tcggtcacta tcgaaaactt gggactggca ggctcgatga
     4321 attcctttgc ccgaaatttg gggatggtca gcgggatttc gctttctacg acggtcttat
     4381 atcaagcgat gtctgctaag atgggccagc aagtaactaa ctatatcgca aatcggccgg
     4441 atgtcttttt atatggaatg aagattacct ttttaggcag ctttgttttg tgttttgttg
     4501 cctttttcct gactatctgg cgtatcaaaa aacaaggagg tattcagaaa aatgtctgaa
     4561 aaaaccactg ttgaagaatt tttggaggcc tgcgtatggg tgagtgggat ttccatggat
     4621 gatggaagat gaagtgaact tctaaaagcc gaaaaactca agtattatct tcaaaatact
     4681 agtgctcaat gagatgcttg atttgatcac aagaagactg cgaaagccgc tggcaaccgc
     4741 aagctaggta tcccaccgat ggactacgtt ttagaggcta ctggttatga atacggagcc
     4801 aacgctctca tctgcataag aatacatcac ccagattatg taaagatttt cgatacttct
     4861 gtcaaaaaat cattaagata gataaatgat ttccgtctag tcaaattggt tcagaatgta
     4921 gacacacaga tggtaagaag tcactcacaa ttcgagaatg gacttgtcct atttgccgta
     4981 tacatcataa tcgaaacgtc aacgatagta tcaatatttt gaccaagggc tatgaataca
     5041 agcattgcct tagaaaacat caagaacctt aggaacaacg gggatagctt ggttaataag
     5101 agataccgct gtttaggctt gcaagtatac tcttttatca agaattccgt ggctttagtc
     5161 atgagaggct taatactatg aaaattttct ttagcatttt tgatttaggt tccttttcta
     5221 attataataa gatgaccact acagtaacct actgaaatat ataaacagcc actgtagtac
     5281 cattttcaaa gtagtctatg agaggagaat cttcattctt atgaacgctg gaattgcgga
     5341 tatgaattta ataaaaaaaa cccttaatga ttttacttcc aattcaatat caaaaggtac
     5401 tggtatcaat ttaagcacaa taaaaaagct gaaaagtggt gaaagatcag tggaaaagct
     5461 gaatctttta gatgctataa aaataacgga atttgctatg aaaaatggaa aagctgagat
     5521 tgaaatatgg agataattat cgtctagtga attacttgcc acttagctga atttaacgat
     5581 ccttggtgct tgaaggggga gattcttggg aatagagcat acttgcaagc ctatgtcttt
     5641 actaacaacg atatctctta ttaaccaagc tatccccgta gttctaaggc ttttactttt
     5701 atctaagcaa taatcgtatt caaaggaaat ttttgaccct tagaaagtct cattttatca
     5761 gacgtgagct taggcattgc tgaattttgt taattcggtt ttaggttgtg ctttgagcat
     5821 aatatgaaag tattctttat cacgatttca ttcatctaag gtaatgtgat gtgattctga
     5881 aattctttca aaggcagttt ttgcataagc tgacattaca tcatcaatga catgtttaca
     5941 atgtttcact actaaaataa gggggtaacc aagaagaaaa actgaatgat tatttgtatc
     6001 taattccatg gtatatcaac catttcctat atagactgat tatgacatgg attaaaataa
     6061 aaaggcacta tgtcttaatt gtcggttttc gagttaccga atggcattca tcacccacct
     6121 atagaggatg ggcgacttct gcctgaaata agttacacta cttataactt ctaataaaat
     6181 tagattgagt cattattatt taacatcaac gattttccag tttccatttt tttgtaatac
     6241 taatttgtac tgaaagtagc tagtggtttt tgatacatta tcaaggtatt ttatctttgt
     6301 actcactaga aaattttttc cgttttgtag ataaactgga ttctctaact ccgaaaactt
     6361 taagtcaata ttgattggtc gcatcgcacc attttcaaca taatactcca attctttttc
     6421 agaagctgat ggataaagtt taaaaaatgt ttctaaaaaa tcggtgattt cttccgttgt
     6481 tttggcatca atttctgaat cgttttctac ttgttttgct tcatattttg ccttgtctgg
     6541 ctttccaatc attgttggca aactagttac taaatgattc ctgttttcat cttcaaagat
     6601 tgtcactcga tatgcagaag aaattgattg cgtctttttt ccctctgtaa tatgttgctc
     6661 cactaaaaat gaaacgacaa attcttccga gtgtttttca acatctagaa tttttacaga
     6721 ttgaacttcg gaactcgtgg gaatatctgc tcgaaccata tcttggatta aagcgagacc
     6781 gttttctgta aggtactgtt cgagattact cattctcttt tcaattgctt ctttgttatt
     6841 tttccatgaa aaatattctt tcgcaaaatc ctctgtaaaa ctttcaacgc cagaagtatt
     6901 cactaccttc tcttttataa ccactttttc atgagttgta tgttgatcaa tggcggtgaa
     6961 atttttataa acgccaaaag caagactaca agacaataaa agccaaaggg caagcaccat
     7021 ttttcgatgc ttacccacgg atacaactcg ttcttttttc ttttttgggc tcttttcctt
     7081 ttgattccgt tcaattttta tcttcattct ttttcctctt ttctcttatt tgtatcggcc
     7141 agctccgata agatgctgcc gccaatagtt ttccgttaga ttcgtccacc ccactggatc
     7201 tcctgcatga aacatgcgat tctcccctgc gtaaatgccc acatgggtca cataagtacc
     7261 ggcatcatag gttgaatgaa agaaaactaa atcacctggt ttggcatctt ttagatcaat
     7321 atgagtcatg gcatcatatt gatcctgagc cacccgagga agtttcaggt caactttggc
     7381 ataacaccat tgggtcaagc cactacaatc aaaccccgtt tctggacttg agccaccaaa
     7441 cacataggcc gttccttcat acttaaatgc ctcatcaaaa atttcttgga ctattttgtc
     7501 atcaaactga gttgtagtta ggtattgctt cactaataaa cagtaaaaca tattgccata
     7561 attataccgc cacccaccat tttccttaat cgcgattggg ttggggtaat cgactttttg
     7621 accacctgat ttttcctttg aaaaagattc agctaaagca aaactatgct tcttcccgtt
     7681 tttcccgaca tgatctagat acccgccacc atagttatag gcctgaataa tactatcttg
     7741 atcacaccct agttctttgg aacgcttaac caaagacgca aaatagagac agccttgttt
     7801 gatggatgcc tcggtactta atgaattagg tggtaatccg gctgactcag aactttgcat
     7861 aacgtcttcc attgtgccac cagattccac ttgaataatc gccaaaagaa ttggaatata
     7921 ctctgttata tccgattctt tggcatactt ttccaccatt gcacggtgtt tcaatacttc
     7981 ttctgagaca ctagttccgc caggagaagt gccagaacta ccatttccct cactgtcttc
     8041 accaaacaac aaacccacac acatcaaaat acccataaaa gagatggtca gaaaagttaa
     8101 tgaaataaca cccactttct tcaagttcat tttttctcac ctgaccttga ttttggacga
     8161 tggttcattc ttttttgtac tttttgattg gtctgctttg gcagagtgga cctctgtttc
     8221 acttgttgga aagaattttt cttacttgct gattggcttt tcccttttga aatgatttct
     8281 tgactagtta gttttcgttt gatttcggga ttcagatttg ctctcacaat ccgctttggt
     8341 gcttcttttt tcagcatcat atctttctga ggttgagctg ctttatctat tggaatattc
     8401 gcccttcttt ttccctgacg atttgttgct tcactcagta tcttgcgttt ttcgtccatt
     8461 ttcgcatttc ttcgttgtcg ttgtttttct cgcaaatcca ctcgatccgc tttttcttgg
     8521 aacagtccgc gcttgaattc ttctggtgct tttttcgact tttcgattcc tttatggaga
     8581 ttgtatttca aattcgttgg cgtattcctt acctgatcct ttacttgttt agtcttatct
     8641 ttcaccaaag cttgggtatc caaaactttg ccgatttttc tcccagccaa attcattcgg
     8701 gattgtttct tattatttga aactggattc tccttagtta agtcagatag tatttcgtga
     8761 tcgttcggta atcgtgaatt ctttcgtaga gaagaaccgg atggcttaaa tttggatttt
     8821 gattgttcct ttgccaactt atttccgact gctgcaccac caccaaaagc caaagctcgt
     8881 cccacatttc gattgagttg ccgcaatttt cgattcatta acatttgcgg ttttcgcatg
     8941 acgcgtcttc ccattgactg gctatcatta ctctggaggt tgaacatact cataatgtcg
     9001 cccaatttga aatagatacc ggcaaaggtc acaatttgca gaaaagcaac catgaaaaat
     9061 ggataggttg ccgaaatatt gaaaaacatc gtggagatgc taaatgcagt cgtaatcacc
     9121 aaagtaacac ccgctcgcat cataatcgta ttgaataaac gaataatcgc cttctttcct
     9181 aaactttcat aagtcggcaa catggacaat aagaaactaa ttggcagaaa catcgcaaag
     9241 ataatgaaga gaatttgcga gaacaacata atccctgtta gaagaaaaac aaagaaggaa
     9301 atgccaatat tgaacaatac caaaaagacc acggtcccta aacggttcat ggtcttggta
     9361 atactgagat tcgcattgtc attgtcttca atctctgcct tgaccgcttc ttcccgatct
     9421 ttgcctttgt tttcatctgg actcacagat agaatcttgt tgacccggtc ttcaccaatt
     9481 tcttctatgt tggaatcatc aaattgcagt agtaaccaag gttgttggac ttgaatcgaa
     9541 aacaaactat cccgaatcaa atccacacta tcttttcctt ggctttctga attgggtaca
     9601 acgatctcgg ttccaagggt aagggccgct tcactaacat ctgagctaaa gtcattgatt
     9661 tttgtgatat aggtaggcgc ataagcaatg aacgaacccg atagtagaaa aatcatcaca
     9721 aaattaatca cggctcgaac tgctttcgtg gtttctcgtt ttaataatcc ggtatacgcc
     9781 acatacaccc ccagagctaa aatcatcaat aatagaaacc caaaataaaa tccggaggtc
     9841 tggagtccat tttcagtaat accagccaat gtttggatat tctttccaat actttcagcc
     9901 gtatccgaaa tgaaatctaa tttgtaagcc tcttgaacca cataacccgt ggcgttcgac
     9961 aaatacaaac tcaccgtcca aatgaaatta gtaatggcat aaagaccata catcacgctt
    10021 ttccctaagc catcacccca attccaaggc aaccaatccc aagagctatc cacaaagaaa
    10081 tctagttgat agttgttcag tgaatatttg gaatatagat ttcctgcttc aactgtatca
    10141 tcaactagcc ctgtcgcctc ggctaccgta ccaactaaac tcaatagaac tatcagagtg
    10201 agtatgctaa taaaaacgat tcccacaatc cgaaaaagtt tctttttcat cccctcactc
    10261 cattctctct tgaacaggtg gacgggtatc aaaggcatgg aagagttctt caaagactgg
    10321 atgtacctga accacgccta cccgaccata caaatcctgc atcaagcatt ggccattttc
    10381 caaatctcgt aggcgttttt gattgctttc atcttctcga tccaagccaa agaattccaa
    10441 ggttttcttg atttcatgaa tatcggtact gcgaaacgca aacttcaacc cgatattatt
    10501 cttcaagcgt tcatccagta aatcatcact attttgcgtg acaaagtaaa ccccggcatt
    10561 catagcccgc ccagcacgaa cgagcttatt cgataatgtt ttcccttgcg ctacttgaag
    10621 aaaactccac gcctcatcta agtctacaat tttgaagatt tctcgattac tatggataaa
    10681 gtccaaggca aaagtggaaa tgacgattag catggaaaca ctaagcaatt ccatggtggt
    10741 atattcttca aaagtggttt ctgcatctgg taaaaccaaa tccgctactt gaatgatatt
    10801 taactgccta tctaaactaa tcgactgggt aatcgaacca tctgagaaaa gcaaatgggc
    10861 aaaatcataa tcggtaaagg actcgatgtg atccgcgata ttttccgcaa ctggtgagcc
    10921 ttcttttcga agctcattaa ttacttgtaa taatccccgt tgattgcttt gggtaaccgt
    10981 ccgaatggcc ttacgcaaca ctggaaactt ctccccatct cgactagaaa ttcctgttaa
    11041 aaaggtcaga atatcaattg ctagactttc agaatccttc tttttctcca taatcacata
    11101 aggatcaagt aatccttgat tttttggctt actagttaag ttgagaatat tgatttcatc
    11161 cgcaatttct ggcaaggttt ctttccagcc accccg
//
LOCUS       DBBGRF010000083        10711 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000083 DBBGRF010000000
VERSION     DBBGRF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.084"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(1..957)
                     /locus_tag="ACIZD4_002680"
                     /pseudo
     CDS             complement(1..957)
                     /locus_tag="ACIZD4_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            1448..2386
                     /locus_tag="ACIZD4_002681"
     CDS             1448..2386
                     /locus_tag="ACIZD4_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC5991540.1"
                     /translation="MKKIDEKLAAEISLKKPAVSNSRLSNSRLSGQTLGKSQPALSFD
                     AMTIVGNLNKTNAKKLSDFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWD
                     RRNMRVEFNPNKLTHEEMIWLKQNIIDYMEDDGFTRLDLAFDFEDDLSDYYAMTDKAV
                     KKTVFYGRNGKPETKYFGVRDSDRFIRIYNKKQERKDNADVEVVSEHLWRVEVELKRD
                     MVDYWNDCFNDLHILKPAWATLEKINEQAMVYTLLHEESMWGKLSKNTKTKFKKLIRE
                     ISPIDLTELMKSTLKANEKQLQKQIDFWQREFRFWK"
     gene            2516..3163
                     /locus_tag="ACIZD4_002682"
     CDS             2516..3163
                     /locus_tag="ACIZD4_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-7 chloramphenicol O-acetyltransferase"
                     /protein_id="HGC5991541.1"
                     /translation="MTFNIIELENWDRKEYFEHYFNQQTTYSITKEIDITLFKDMIKK
                     KGYEIYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWT
                     ESDKNFISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNS
                     SFLLPIITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDIIHRVDDWI"
     gene            complement(3856..4794)
                     /locus_tag="ACIZD4_002683"
                     /pseudo
     CDS             complement(3856..4794)
                     /locus_tag="ACIZD4_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            complement(4794..5411)
                     /locus_tag="ACIZD4_002684"
     CDS             complement(4794..5411)
                     /locus_tag="ACIZD4_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5991542.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVIVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINSLVIELYKYQAESERKKIKERQAQGIEIAKKKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
     gene            complement(5425..5595)
                     /locus_tag="ACIZD4_002685"
     CDS             complement(5425..5595)
                     /locus_tag="ACIZD4_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991543.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            complement(5943..7433)
                     /locus_tag="ACIZD4_002686"
     CDS             complement(5943..7433)
                     /locus_tag="ACIZD4_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HGC5991544.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            complement(7476..7775)
                     /locus_tag="ACIZD4_002687"
     CDS             complement(7476..7775)
                     /locus_tag="ACIZD4_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991545.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            complement(8141..8425)
                     /locus_tag="ACIZD4_002688"
     CDS             complement(8141..8425)
                     /locus_tag="ACIZD4_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5991546.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            complement(8944..9429)
                     /gene="vanZ-A"
                     /locus_tag="ACIZD4_002689"
     CDS             complement(8944..9429)
                     /gene="vanZ-A"
                     /locus_tag="ACIZD4_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HGC5991547.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(9582..10493)
                     /locus_tag="ACIZD4_002690"
     CDS             complement(9582..10493)
                     /locus_tag="ACIZD4_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HGC5991548.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         3308 a         1864 c         1658 g         3881 t
ORIGIN      
        1 acttttttct gcttcttttt ctttctgttc ctggtaatca gaaaaattta gtttttctat
       61 atcgttaggt acagcttcca gtaaatgaac aatgaatttt ttgatattcg taataaagtt
      121 ctcttgattg ccttctcttt taccgatttt ttttaaatac gtttcccatt tagccgtcat
      181 ttcagcactc gttaaaaggt gctgactttc aactgcctgg cacaataatt ttcctttttc
      241 agttacaaca agcttattct taatcacttg gatatattct ttttgtttta acgcttcaat
      301 aatacttgct cttgtcgctt ctgttccaat cccctcaact tcttgtaaaa tcttgattgc
      361 ttcttcatca tcaaccgttt tattcgccgt tttcatagca gttaataatg taccctctgt
      421 aaaagctttt ggcggttgcg tttctttttc aacactctta acaccaactt cggcacgttc
      481 gccaatgata acgagtggta acgtttgaac gtcctctttt tcttctttgg tttgttgttt
      541 gaaaagaatt ttccaccctt cttgctttgg tgtctttccg atcgattgaa acagcaaatc
      601 agctactttc gtttgtatct tggtttcttc atacaagtaa tcaggtaaaa acatggcaac
      661 ggtcgtttta acgactaaag cataaatttt tcgttgtaaa tcgtccattt tcgctaatgc
      721 agattcggta ggtacttgtt ttgttgggat aatggcgtgg tgttcctgta ccttactacc
      781 gtccacataa cgctttctag gctctgtttg aaccatttca agatcaagtc ctaaaaaacc
      841 gctatatttg ccaaaattcg cttttaaata agcaaattcg ttctctgtaa taaatggtgt
      901 atctgttctt ggataactca ataattttgc ttcatacagt ccttgcatag cttttaaacg
      961 taaaattttg cgttctaaga cgttttaaat atatctgcgt atatttttat gtgttttatc
     1021 ttttcgtcgg caaatgcgtt aaaatttgcg aaataaaata gctcaagggc gaacgcagtg
     1081 agtgcattta cccttgatct atttttttga gtaaattagc ttttgaaacc gacggaaagg
     1141 aaacacaaaa cttttcagag gcaaggggtt tttaaggggc gcttttagcc ccttgaattt
     1201 atttgcttta agatatattt agttttaaaa tagttttaac gaaaaaaaga cataaaaaaa
     1261 gacgagcaac gctaccaacg ttctcgcccg gaataacaaa ccacacttgt tattcattcg
     1321 atgattagta tatcaatttt tgattttgaa tacaaaacaa aatggacgaa tggatacagg
     1381 cgaaatttat tttgcgattc cactcgtcct tttttcgttc caaaaattat tttaggagcg
     1441 ataaaaaatg aagaaaattg atgaaaaatt agctgcagaa atctcactaa aaaaaccggc
     1501 cgtctctaat agccggttaa gtaatagccg gttaagtggt caaactttgg gaaaatctca
     1561 acccgcatta agttttgatg ccatgacaat cgttggaaat ttgaacaaaa ctaatgctaa
     1621 aaagctatct gactttatga gtgtagagcc acaaatacga ctttgggata tacttcaaac
     1681 aaagtttaaa gctaaggcac ttcaagaaaa agtttatatc gaatatgaca aagtaaaagc
     1741 agatacttgg gatagacgta atatgcgtgt tgaatttaat cccaataaac tcacacatga
     1801 agaaatgatt tggttaaaac aaaatattat cgactacatg gaagatgacg gttttacaag
     1861 attagactta gcttttgatt ttgaagatga tttgagcgat tactatgcaa tgactgataa
     1921 agcagttaag aaaactgttt tttatggtcg taatggcaag ccagaaacaa aatattttgg
     1981 tgtccgtgat agtgatagat ttattagaat ttataataaa aaacaagaac gtaaagataa
     2041 cgcagatgtt gaagttgtgt ctgaacattt atggcgtgta gaagttgaat taaaaagaga
     2101 tatggttgat tactggaatg attgttttaa tgatttacac atcttgaaac ctgcgtgggc
     2161 tactttagaa aaaattaatg agcaagctat ggtttatact ttgttgcatg aagaaagtat
     2221 gtggggaaag ctaagtaaga atactaagac taaatttaaa aaattgatta gagaaatatc
     2281 tccaattgat ttaacggaat taatgaaatc gactttaaaa gcgaacgaaa aacaattgca
     2341 aaagcagatt gatttttggc aacgtgaatt taggttttgg aagtaaaata agttttattt
     2401 gataaaaatt gctaattcag tataattaat atttacgagg tgacataacg tatgaaaaaa
     2461 tcagaggatt attcctccta aatataaaaa tttaaaattt aggaggaagt tatatatgac
     2521 ttttaatatt attgaattag aaaattggga tagaaaagaa tattttgaac actattttaa
     2581 tcagcaaact acttatagca ttactaaaga aattgatatt actttgttta aagatatgat
     2641 aaaaaagaaa ggatatgaaa tttatccctc tttaatttat gcaattatgg aagttgtaaa
     2701 taaaaataaa gtgtttagaa caggaattaa tagtgagaat aaattaggtt attgggataa
     2761 gttaaatcct ttgtatacag tttttaataa gcaaactgaa aaatttacta acatttggac
     2821 tgaatctgat aaaaacttca tttcttttta taataattat aaaaatgact tgcttgaata
     2881 taaagataaa gaagaaatgt ttcctaaaaa accgatacct gaaaacacca taccgatttc
     2941 aatgattcct tggattgatt ttagttcatt taatttaaat attggtaaca atagcagctt
     3001 tttattgcct attattacga taggtaaatt ttatagtgag aataataaaa tttatatacc
     3061 agttgctctg caacttcatc attctgtatg tgatggttac catgcttcac tatttatgaa
     3121 tgaatttcaa gatataattc atagggtaga tgattggatt tagtttttag attttgaaag
     3181 tgaatttaat tttatacacg taagtgatca taaaatttat gaacgtataa caaccacatt
     3241 ttttggttgc ttgtggtttt gattttgaat ttggttttga acttatggac tgatttattc
     3301 agtccatttt ttgtgcttgc acaaaaacta gcctcgcaga gcacacgcat taatgactta
     3361 tgaaacgtag taaataagtc tagtgtgtta tactttactt ggaagatgca ccgaataaaa
     3421 aatattgaag aacaactagc aaaagatttt aaagagttat tttattttaa gtctttataa
     3481 catgagtgaa gcgaattttt aaatttcgat agaaattttt acatcaaaaa gccccctgtc
     3541 aaaattgacg aagggggttt tttggcgcac gcttttcgtt agaaatatac aagattgaaa
     3601 atcgtgtata agtgcgccct ttgttttgaa cttagcacgt tacatcaatt ttttaaaatg
     3661 atgtataagt gcgccctttt aaattttgag tgattatatt ttttgagtta gaaaaaggga
     3721 ttgggaaaat ttcccaaaat aatttaaaaa ataagcaaaa attttcgata gagaatgtgc
     3781 tattttttgt caaaggtgta taccttgact gtgcttgctg ttacattaag tttattttta
     3841 agttattaaa aaagaaatag cttttaaagt ttggctcgct gtcgctttat aaagctgatt
     3901 gacttttgat tgcaaactac ttaaagaaaa caaactcgga ctattcgttt tcttctcttt
     3961 ggtttgaaca tcagcaatta tcccctcttg attgcctatt ttagcttgtt tagaagaaac
     4021 aaaagctaaa agctcctctt gggttttaaa acgctgtgtg gggcttagaa cgcccttaaa
     4081 cgacccttgg tttactttta tactagcttc cacctcgaaa aaaggttctt ttttaaaatt
     4141 ctctatggct tcctggcgct gaaaaataag gtataaggtg ggcgtttgaa cacgtcctag
     4201 tgaaaatgta ccttgtacgc ccttctgttg taaatttaac gtatacaaag ggcttgcgtt
     4261 catgccgatc aaccaatcgg caatttggcg tgtttgcgct tcttgataaa agggatagta
     4321 attcattcca ggttgcaaat tttgaaaacc gcttcggatt acatcttttt ctaagctatt
     4381 gatccatagt cttttaaatg ttttatcttt tgaaaaggca tttgctttat ggataatcga
     4441 ccaggcgata ttttcacctt ctctgtcgct atctgttgca acaataattg tatttgcctt
     4501 tttgagaagt tctgcaacaa ttttaaactg ctttccctta tcttttgcaa cttcaaaatc
     4561 gtatcgatca ggaaaaatcg gcaaagattc aagtttccaa ttttgccact tttcgtcata
     4621 atgacctggt tctgctaatt ccactaaatg cccaaaacca aaggtgataa acgtttcatc
     4681 tgtaaatagt gggtctttga tctcaaaata accgtctttt ttggtgcttt gttttaaagc
     4741 acttgcgtag gctaatgcct ggcttggttt ttcagctaaa ataaccgtac tcattaacta
     4801 tccctctttt cattgttttt tctttgatcg actgtcacgt tatatcttgc tcgatacctt
     4861 ctaaacgttc ggcgattgat tccagtttgt tcttcaactt ctttatcgga taaaccattc
     4921 aaaaacaaat cgaaagcatg ctttaaacgt ggatcatttt ctttaaattt atgctgacga
     4981 cctttgaatt tgcctttttt cttagcaatt tcgattcctt gtgcctgacg ttccttaatt
     5041 ttttttcgtt ctgattctgc ttgatacttg tacaattcaa tgacaaggct attaatcaaa
     5101 cgccttaaat tttcatcttc aataccattc attgagggta aatttaagac ttccagggtt
     5161 gcccccttaa tttgaatttg attcatcaat tctgttaatt ctttattatt tcgtcctaat
     5221 cgatctaatt cagtaacaat aacaatatcc ccttcacgaa tatagttaag catagcttgt
     5281 aattgtgggc gttcgaccga ttgaccgctt aatttgtctg aaaagacctt agaaacgccc
     5341 tgtaacgctt gtaattgccg atctaagttc tgttctttgc tactgacacg tgcataacca
     5401 attttagcca ttttcaacca acctctaaaa ttctctcggt tgcaataacc aatcagcaat
     5461 atctactttt tcaatttcaa attgcttatc agaaattgtc ttttcgtaag cgataaaatc
     5521 ttgcgcatat tgttgctcat taaaaatagc caccacttcg tcattttcta aaactcgata
     5581 aataaatttt ttcattttac tcctcctatt atgcccaact taaatgacct attcaccaag
     5641 tcaattatac tgctaaaatc atattaggac aaataggtat actctaatga cctataaaag
     5701 atagaaaatt aaaaaatcaa gtgttcgctt cgctctcact gcccctcgac gttttagtag
     5761 cctttccctc acttcgttca gtccaagcca actaaaagtt ttcgggctac tctctccttc
     5821 tccccctaat aattaattaa aatcttactc tgtatatttc tgctaatcat tcgctaaaca
     5881 gcaaagaaaa aacaaacacg tatcatagat ataaatgtaa tggcatagtg cgggttttat
     5941 tttcagcctg tatcatagct aaacaaatcg agttgtgtgt ccgttttagg gcgttctgct
     6001 agcttgttta aagtctcttg aatgaatgta tgctctaagt caaaagaatt tgtcagcgcc
     6061 tttatatagc tttctttttc ttcttttttt actttaatga tcgatagcaa caatgattta
     6121 acactagcaa gttgaatgcc accatttctt cctggtttaa tcttaaagaa aatttcctga
     6181 ttcgccttca gtaccttcag caatttatct aatgtccgtt caggaatgcc tagcacttct
     6241 ctaatctctt ttttggtcgt cactaaataa ggcttgtata catcgctttt ttcgctaata
     6301 taagccatta aatcttcttt ccattctgac aaatgaacac gttgacgttc gcttcttttt
     6361 ttcttgaatt taaaccaccc ttgacggaca aataaatctt tactggttaa atcacttgat
     6421 acccaagctt tgcaaagaat ggtaatgtat tccctattag ccccttgata gttttctgaa
     6481 taggcacttc taacaatttt gattacttct ttttcttcta agggttgatc taatcgatta
     6541 ttaaactcaa acatattata ttcgcacgtt tcgattgaat agcctgaact aaagtaggct
     6601 aaagagaggg taaacatgac gttattacgc cctattaaac ccttttctcc tgaaaatttc
     6661 gtttcgtgca ataagagatt aaaccagggt tcatctactt gttttttgcc ttctgtaccg
     6721 cttaaaaccg ttagacttga acgagtaaag cccttattat ctgtttgttt gaaagaccaa
     6781 tcttgccatt ctttgaaaga ataacggtaa ttaggatcaa aaaattctac attgtccgtt
     6841 cttggtatgc gagcaatacc aaaatgatta cacgttagat caactggcaa agactttcca
     6901 aaatattctc ggatattttg cgaaattatt ttggctgctt tgacagattt aaattctgat
     6961 tttgaagtca catagactgg cgtttctaaa acaaaatatg cttgataacc tttatcagat
     7021 ttgataatca tagtaggcat aaaacctaaa tcaatagcgg ttgttaaaat atcgcttgct
     7081 gaaatagttt cttttgccgt gtgaatatca aaatcaataa agaaggtatt gatttgtctt
     7141 aaattgtttt cagaatgtcc tttcgtgtat gaacggtttt cgtctgcata cgttccataa
     7201 cgataaacgt tgggtgtcca atgtgtaaat gtatcttgat tttcttgaat cgcttcctcg
     7261 gaagtcagaa caacaccacg accgccaatc atgcttgatt ttgagcgata cgcaaaaata
     7321 gcccctttgc ttttacctgg cttggtagtg attgagcgaa ttttactatt tttaaatttg
     7381 tactttaaca agccgtcatg aagcacagtt tctacaacaa aagggatatt cattcagctg
     7441 ttctcctttc ctataaatcc tataaaatag gttgtttaat taacttggtt tgctttttca
     7501 ttcaactgtt tcaatattgc atgttttgaa aaagattttt ttcctttata agtcaatttt
     7561 tttccactaa tcgaataaat tattttgtta ttttctatta acttatatat ataatcttcc
     7621 ccctccgaag aaaaatactt atctgatttt gtttctaagt agatatttct cttttctaac
     7681 tctttcttaa acgtttctag tgtatagata tttgctaatt ttcttatctc caataaacta
     7741 ttttttatat aagttttaca ttcatcatga ttcatacaaa ctccaccttc tataaatgaa
     7801 tacaaaaaaa gcaatcaaac gatttccgat tgattgctta acaattctta aattcagtag
     7861 cttagatact tgaaaactct ctgatttccc tatataatga tagtacggtt atataccgtc
     7921 ttcaaacaaa gttaattaaa taacttctta cgagggaaga gttcatctga ctaactgata
     7981 agcgttggtt tggcaatctt atcgggctat gcatttataa aatgtcgtca aacattttat
     8041 aaatgtgtca tggctctttt ttcgtttcta ttcagttcgt tgtttcgtta tatctagtat
     8101 accgctttta aaaaaaataa gcaacgattt cgtgcattat tcacacgaag tcattgcttt
     8161 tttcttcttc catttctaaa tccaatgtta cttgttctga ttctgtttct ggttctggtt
     8221 ctgttggctc atttgggatt aaatccacta ctagcgttga gttagttaac tttgcaattt
     8281 gttctagtgt ttttatggtt ggatctgatt ttcctgattc tattcgtgaa taatttgatc
     8341 tactcatttc taattcttgg gagaattttt cttttgattt ggtacctctc atctttttta
     8401 agctttctct aaatgctagt tccaagtttc tcccccctct ttttgtgtaa taaaattcac
     8461 gctttattta aattatagct tttaatatct taataaacaa gtgattaatc acttgtgatt
     8521 tgtgattatt ccaaaagtag gtaatttcac caaccttttt caaaagtttt tatcgacgat
     8581 tattggactg gatcgtgttt cctaaagcga ttctaagcgc atgtttaatt ttaaagtggg
     8641 taattctctt taaaacgtcc tacaaagatt caaaaaaagc atggctgcta gtgggggtac
     8701 cgtcaggaaa atgcggattt acaacgttaa ggaaatttat taaagagacc aattcctcag
     8761 cactaaaatt gataattggg ctttctttgt tactatagtg ttaggtaagc tttttacttt
     8821 atcaccggtt ttcccctcac ttcacaccta cgggcgagtt tccccacatc ccgttttcca
     8881 tctaatccaa ttcattcaat atctttatgt gtatgaaaga tcagattgct tgatttagac
     8941 atcttacacg taatttattc ttaaatgggt acggtaaacg agcaataata cgagcaaaag
     9001 tatacctaca aaaataataa ctctgtctaa ttttttttga ttcatatgct tattgcttaa
     9061 accatataat ttcagtccaa gaaagcctcc aacagtattt gtaattacat ctgttatgtc
     9121 tgtcgctcca atagcgaaga taaattgaat tatttcaaaa gtaagactta aaaccagtac
     9181 aaaagcaaac ttaggtaaaa atccgatttc tttaaaattg acattcaaaa gcaagccaaa
     9241 tggaataaag attataacat tatctatcat ctctctgaaa ttcccagtag cagtaaatgg
     9301 agtcaagtta agacttcttt gatgataatt aaatactgat aaaatattgt attgtaattt
     9361 gaataacact aaccagatta gtgtcactaa atataaagct agcaatcctc tagataatat
     9421 ttttcccaat ataatttcct ctaattcttt tgtttaagtt gtatcattag tatagcaatg
     9481 tcctagttaa cgtgggtttt aaattaaaaa gctaacgtta ccccaaaagt gctagtacaa
     9541 taatgctgtt cattaatttc gttggtttca ttccgccatc cttacctcct tgaattagta
     9601 tgtgttgatc cgggaaacac tgtcacaatt acaccgtcta tattgtttcc tgatatctca
     9661 taacgaagat tagtcggcac atgaatggtg gtatttttag taacaggata ataaaagatc
     9721 tcatattttt ccccatttac actaacagaa atggtttttt cttcttttag gtaatccata
     9781 tattcctcga gaacgaaatt cttttctttc ataatcgcac tatgtggtaa accaacatag
     9841 cgaatatgcc atggttcata ttgaattcct gttaactctg ttttgtcctc tggataacgt
     9901 aaaatgaacc cgtatttcca agcattttct tctatccact ttccttcagg ggctcgttcc
     9961 attttcgtca agcttgatcc tacatctagt gataaacctg aattatgctc actataacct
    10021 gctggtaagg catactcagc ccccatttct tggtaaagca cactttgctc atcaaagtct
    10081 cgatagccac tattaataat aaaatgacta acgccaccct ttacagcatc attgaccatc
    10141 tctgaaaatt tttgtgctat ttcttttgac atataaatat tactatcaag caacccgtat
    10201 ccatttatta attcgtcatg tttagataaa ttcacgatat ctgacttcac actttcttgg
    10261 cgaacaggat atttactatt gattaatagc agatttcctt gataaacctg ttcttctgta
    10321 attgttttct cttgggtatt ttcagaagtc ccactatttt ctaaatgttc tttgggattt
    10381 tgatcataat tttgaaattc gactttttcc tgagaaaaca gtgcttcatt aacgtagtca
    10441 taacctaagt atattaagaa taacaataac aataaaaaaa acaacttctt cattttcagt
    10501 ctcctcctta actatatagt tggaagtatg aaatatttct agaatcttcc ccttaaacgg
    10561 cacaatctcg tttgagattg tgccgttttg ccccgtaaat tacagtcaat tatttcgccc
    10621 tactggattt actattatca ccaatgtaga tgaattttca taagtgatac ccatgctgaa
    10681 tttaacgagg ctgaactgcc tgttgacaat g
//
LOCUS       DBBGRF010000084         9811 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000084 DBBGRF010000000
VERSION     DBBGRF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.085"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(34..2154)
                     /locus_tag="ACIZD4_002691"
     CDS             complement(34..2154)
                     /locus_tag="ACIZD4_002691"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HGC5991549.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2384..3562
                     /locus_tag="ACIZD4_002692"
     CDS             2384..3562
                     /locus_tag="ACIZD4_002692"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGC5991550.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3578..4336
                     /gene="aroD"
                     /locus_tag="ACIZD4_002693"
     CDS             3578..4336
                     /gene="aroD"
                     /locus_tag="ACIZD4_002693"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGC5991551.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFFSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4359..4844
                     /gene="ybaK"
                     /locus_tag="ACIZD4_002694"
     CDS             4359..4844
                     /gene="ybaK"
                     /locus_tag="ACIZD4_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HGC5991552.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4915..6168)
                     /locus_tag="ACIZD4_002695"
     CDS             complement(4915..6168)
                     /locus_tag="ACIZD4_002695"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC5991553.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6285..7634
                     /gene="gdhA"
                     /locus_tag="ACIZD4_002696"
     CDS             6285..7634
                     /gene="gdhA"
                     /locus_tag="ACIZD4_002696"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGC5991554.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7746..9092
                     /locus_tag="ACIZD4_002697"
     CDS             7746..9092
                     /locus_tag="ACIZD4_002697"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGC5991555.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9400..9786)
                     /locus_tag="ACIZD4_002698"
     CDS             complement(9400..9786)
                     /locus_tag="ACIZD4_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC5991556.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3128 a         1782 c         2009 g         2892 t
ORIGIN      
        1 aattttgtcg ctgctccttt taaatttatt ttatcattcg gaagaacttg tggtcgttcc
       61 gtgaagttct tggtacgttt gcgttttata aagatcaaca gttgattgtc cgttgtgttc
      121 actaaagaca ctagttgact tgtcaccaag agatttttca gcttctttta atttctctaa
      181 gccattcttg tagtcataat cactggtatc aattgggtct aatccactat tcgtatagaa
      241 ccgaagaaga tcaccattat tgatttggtc agaaacagct aactgtttat caactttttc
      301 tttcagtgaa tcaatttcat tctgtacttc ctcagtaggt tcagtaatag cttcaccagt
      361 ttcgttacta tagatcgtac caccgtagta agtatatttt ggtgtaacaa aatcaccatc
      421 acggaaagaa acaagctgtt catgatcttt cgagaataga tcttgtccta actgaatata
      481 attttttgta tctacaccta gtaagtgaag taatgtaggc aaggcatcaa cttgtccgcc
      541 gtaagtgtga ttgattccgc cctgtgtttg tccagggata tggatcatat aagggacacg
      601 ctgcatttgt gcattgtcgt agtttgtcca agtagaactt gtttttccaa ctaattcagc
      661 tagattttta tttcttgaat tcgagacacc gtaatggtca ccgtaaagga cgatgactga
      721 attatcatac aagccgcttt ctttcaaata attgaagaat tcttgtacgg cggtatctaa
      781 ataattggct gtcgcaaagt aaccgttgat cgtttcatca tttgtattgg ctaacgggaa
      841 tcctgcttcg tcattggtga attttgaata aggataatgg ttagatacag caatgaattt
      901 tgaataaaat ggttgttgca gacgttccaa gtattgtacg gattgttgga aaaatggttt
      961 atcatgcaac ccgtattgga acgaattgtc atcattaaca tcataataag aagaatcaaa
     1021 gaaataatca tatcctaaat tcttgtatgt ctcgtttcga ttccagaatg taccagcgtt
     1081 cccatggaat accgcactaa tgtaaccttg tgtttgactt aaaatatcag gtgcagcttg
     1141 gaaagtattt tttccgccta attgtgtgaa caaggagcct tgattcaagc caaacaatga
     1201 attttccatc agcgtttccg catcgcttgt ttttcctgct tttacttgat ggaaaaagtt
     1261 gtcaaaactg aacgtgctgt tgctgtggta aagactattg atgaaaggtg taacttcatg
     1321 ctggagacca ttctcatctg tcaatttata atcgatcagg aattgctgga agctttctaa
     1381 atggatataa atcacatttt ttcctctagc gagcccgaac aaatcgtcat ttggtgctgc
     1441 ataatgttct tttacataat tttctacttc tttcatatca ttgggacttg cttctgcccg
     1501 cacttggttt gtctggtaag tttgaacacc gtcataaacc atgaaagcat tcaagccaag
     1561 atatttgacc aaataatcac gagagaatgt tcgagtcagc aattctggac gatcagcttc
     1621 cgccataaaa agatttcctg agaaaatcat aactgctaat gtagagatcg caaaagccat
     1681 tcttgctcgg atcgggcgag ggtccaactt gatttttttt gcaatcagca gaacagtcaa
     1741 gataataaaa tcgatccaat agatcacatc atatgggcga aacagtcgaa tggcactttc
     1801 tcccagacca ctcgctactt tcccagcacc taaaatcgtg ttgatcgtaa tgaagtccgt
     1861 gaattctcga taataagtga cattcgaaaa aacaagcaat gtcaaaagaa aataaatgac
     1921 catcatcgtg atataagcaa ctctagggcg tctgatataa agagcaattc caagtaataa
     1981 caatgtagtt gcaatagggt tgataaacaa gataaagtat tgaatgccac tttcgattcc
     2041 gagatggaaa tcaactaaat aggcaaaaat cgttttcaac caaagtaaaa cgactagtaa
     2101 agaaaaaaat ccgagcctct tattcaaaaa ggcaggtgtt tttatacatt tcaagataat
     2161 cttcctttct gcacttctta atcacagaag tgtcctgaaa ccatgttaca cagctcactt
     2221 attctcattt attttactag tatgacaata tagtgtcaat tgaaaccaga agtttatgct
     2281 gtttcattaa ggttttcttt aagcttcatg aaaaaatgag cagtaagaca agtcctatgt
     2341 tttttgttat acttgggaag agaaagctaa agcaggtgaa ggaatgaaag taaaagtaaa
     2401 aaaaagagca agcaatcgat tgaaaaaagg atatccactg atccaaaaag aagaccttgc
     2461 tcatccccaa aaagaaacca cgcaatgggt ggaattagtt gattcgcaaa accaatttat
     2521 cgcaaaagga tatctaggaa agcagaataa gggaatcggt tgggtattga gccagcagaa
     2581 catcccattt gatcaatctt tttttgaaga attttttgtg aagtcaaaag aaaaaagaac
     2641 tttctttttt tcagatgatt ctactaccgc ttttcgtata ttcaatggag aaggagacgg
     2701 gatcggcggt ctgattgttg attattatgc aggttatgct gttttttctt ggtataacga
     2761 aacgttatat gcacatcgtg aattattgat tcaagctttt cgtgaaatct acccggaaat
     2821 cataggaggc tatgagaaaa ttcgatttga atcagtaaat ctgcctgaga gccagttcat
     2881 ttacggaaaa gaggcaccgg aacccttgat cgtaaaagaa aacggagtaa aatttgccgt
     2941 ttatttaaat gaaggattaa tgactgggat ctttttagac caaaaagaag tacggggatc
     3001 attagcagaa ggtttcgctt ctgggaaaac agttttgaac atgtttagtt ataccggcgc
     3061 cttttctgtt gctgccgcaa tgggaggggc aatcgaaaca acaagtgtcg atctagcaaa
     3121 acgcagttta aaaaaaacac aggaacagtt tgaagtgaat ggtttggatg tcgatcagca
     3181 aaaaatcatt gttatggacg tattcgagta tttcaaatac gccaaaagaa aacaattttt
     3241 atatgacatg attgtattgg atccaccaag ttttgccaga aataagaaaa aagtctttcg
     3301 cgtagcaaaa gattatgggg aactggtcaa ggatagtctg gatattttag cagaagacgg
     3361 gatacttatt gcgtctacaa atgctgcgaa tgtctcgata gaacaattcc aaacaatgat
     3421 tgaagaggaa ttccatgcca aaaatgtttc ttttgaacaa cttgctttat atcgtctgcc
     3481 aaaagatttc cagacgacgg ataccttttt agaaggcaat tatctgaaag tgtttgttta
     3541 tcaaattaaa aataaccatt agaaggagcg atgcagaatg gttcgggtaa agggattgaa
     3601 tataggaagc ggtagaccaa agatttgtgc gcctcttatc ggggccgtcc gagaggaagt
     3661 attacgtgaa gcagttcttg cacgtgaagc aggggccgat ttagtcgaat ggcgagtcga
     3721 tcattatcgt gaagtttttt cttttgatga agtagcagaa acattggttc ttatccatga
     3781 gatgcttgat ggactgccgt tattatttac gtttcgtacc ttagctgaag gcggagaaca
     3841 agacatatcg atccgtcagt atcgcgacct ttatgaacat gtgatacaca caggattagt
     3901 agatatggtc gatatcgagt tgttcaaagt agaaagtcta ggaaaaagac tgatagagga
     3961 aatcaagtct ttaaacattc ctttaattat cagtagtcat gattttaaag aaacaccagc
     4021 agaccctgtc ttgctttacc gattgaatgt tatggaacat tttggagccg atatcggaaa
     4081 actggcagta actcccaata atgaacgaga tgttttgcgg ttgatggagt tgactagacg
     4141 ggcaaatgct tttttctcca tgcctattat tacgatgtcc atgggaaatc ttggtaaaat
     4201 ttctcgtctg gttggcggaa cgacgggttc cgttatgaca tttggttcct taagcagcga
     4261 ttctacttct gctccaggac aattaccggt caaagcattg aagcaaatta ttcaattatt
     4321 aaatgaaccg ttgtagaaca agtttgaggt gatatttttt ggcaaagaaa aaaatagtaa
     4381 aaacgaatgc aatccgtatg gtcgaacaaa aaaagattcc ctatacagag cacgaatatg
     4441 agtgggacga aagccaccta agtgcgtcat cggtcgctga acagcttcca gaaagccaat
     4501 ctcgtatatt taaaacactg gttgctgtgg gcaatgtgac ggggcctctt gttgctgtga
     4561 taccgggaga agccgaattg aatctaaaaa aattagcaaa agtttcaggg aataaaaaag
     4621 tagaaatgct ccatttaaaa gatttggaag caacgaccgg atacatacgt ggtggctgct
     4681 cgcctatagg tatgaaaaaa ctatttccta cttatttaga tcaaattgca gaaagctatg
     4741 aacaaatcat tgtctcggct ggcagaagag ggctacagat ggagttagca cctcaagata
     4801 tctgtgcatt aacgagcgga caatttgcag atataaaaca ataaatcata cgtataaaag
     4861 aaagaaggag gccgggatgt tgtttgtcca gtctccttct ttctttttta tacattatgc
     4921 tctttgcccg gcattcattc ctgctacatg ccctgtagcg aaagccgctg tgatattaaa
     4981 gccgccagta taaccattga catccagtaa ttctcccgca aaatacagac catcaatgat
     5041 tttactctcc aatgttttag gataaatttc ctttagagaa acccctccgc cagttacaaa
     5101 tgatttctca ataggaaaag ttttgttgat tgatagctta aactctttgc atagttgaac
     5161 aaaatcttga atttgttttt gagaggcttg ttgtcctgtc agatgatcca tttcaagccg
     5221 ctcaagaaag aaaactaaca atcgctcagg caatatacca tgccaagcat tgaccaagtt
     5281 ctttttggtt gctttacttt tttctgtcaa tatatgaata agctcttgtt tggtttgtgt
     5341 agggaaacaa tccagagaaa gtgtcactgg ttctcccgtt ttctctaatt ctttattgac
     5401 aaaacttgaa caacgcagtg cagccggacc agaaataccg aaatgggtga aaagtaaatc
     5461 catcgtatgt tcagtcaata cacgaccttt tttatttaaa acgcgtaaag tgatgtcttg
     5521 taaagaaagc ccttgaagtg ttttctcctg aatatacggt tcatccgata tcaaggggga
     5581 ctctgtcgca taaagaggcg tcaccgtgtg acccactcgc ttcacgatct tgtacccatc
     5641 tccagtagaa ccagtagatg gataagtccg tccaccagtt gttaagataa tggcaggagc
     5701 atggaactct tcgaattccg tgcgtatacc gtaaatttta tgttctttgt ggatcaattt
     5761 ctctactcga gtagagaata gaagcgtcac atctagttct ttcagacgat tgagcaatgc
     5821 ttcgataatc gtttttgatt tatttgttac aggaaacatc cgtccatgat cctcttcttt
     5881 taaatgtacg ccttgtgatt caaagaagtt catgatatcg aaattattcc attgcgcaaa
     5941 cgtactatat aaaaactttc catttccagg aatatgtgca atcaaatcat caacaggacg
     6001 attgttcgta acattgcacc gaccaccacc tgtcatcagt agtttttttc ctgctttttt
     6061 gtttttttcg atcaagagta cgcgtgcgcc ttgttcagct gcactgatcg ctgccatcat
     6121 cccgcttgtt ccagcgccga ctacgatcac atcatacagt ttttccattc cctcacctca
     6181 aggaaagtgt agcatatctg aagaaagaaa acagaaaaaa atgttttgag ccaaaagaga
     6241 aaatgagcta aaatgaggga agataagcaa aggagcgtgg aacgatgaca aacgcaacag
     6301 aatatgttca agcaattcaa gaaaagctac atcaaaagga tcaagggcaa gaagaatttt
     6361 tacaagcaat cgatgaattc atgcccacgg ttatgtcttt tttggacact catcccgaat
     6421 atatcgaaaa gaatatctta gaacttttaa cggaaccaga aagagttatt caatttcgag
     6481 tgccttggca agatgatgaa ggaaactggc gagtaaatag agggtaccgt atccaataca
     6541 actcagctat cggcccttat aaaggtggat tgcgcttcca tcctagtgtc aatctaagta
     6601 tcttgaaatt tttggctttt gaacagattt tcaagaatag tttaaccggt ctgccaatcg
     6661 gtggaggaaa aggcggaagt gacttcgatc ctaaaggaaa atctgataat gagatcatgc
     6721 gtttttgtca aagtttcatg ctggaattgt caaaacatat cggcccatcg attgatgttc
     6781 ctgcgggaga tatcggtgta ggagctagag aaatcggcta tttgttcggc gaatataaac
     6841 gattgaaaaa atatgatact ggtgtgttga caggtaaacc tttggatttt tggggaagta
     6901 agatacgtac ggaagctact ggttatggat tagtgtatta tgtcaaacat ctattgaacg
     6961 aagaaaaaga ttcatttaat caaaaaacag tttttgtttc cggaagcggg aatgtagcca
     7021 tttatgcaat cgaaaaagtg caagagctag gcgggaaagt tgttacatgt tcagattcta
     7081 gcgggtacat ctatgatcca gaaggaatag atgtgaaact attgaaagaa gtcaaagaaa
     7141 tcaatagaca acgtttgacg gaatacgcaa accaacgtcc ttctgctatt tatcatgctg
     7201 gagaatctgt ttggacattg aaagaaaaag cggatatcgc tttgccatgt gctactcaaa
     7261 atgaaataga cgaaagcttg gccgaaatct tagtagaaaa tgggatcaaa atcgtagcag
     7321 aaggcgctaa tatgccatgt acagtaaaag ctgtttctgt tcttcatgaa gcaggcgtgt
     7381 ggtattgtcc aggaaaagct gctaatgctg gaggagtagc agtatctgct ttagaaatga
     7441 gtcagaacgt ccagcgattg acttgggaaa gagagcaagt ggatgagcag ctggatcaaa
     7501 tcatggaaac gatttaccat acgtgtcgcc aaacagcagc cgagtacggc gacgaaaaaa
     7561 atctgcttct tggagcaaat gttgctggat ttgaaaaagt tgccaaagca atggcagcag
     7621 aaggtttagt ttgaaaaatg aaactttctt ggaaatattg tcagcatttt gtttatttgc
     7681 ttgaaaaata ataaaaaaaa acgtaaagta ttacctgtag agtaaaccta taaggaggag
     7741 aacaaatggc acacattcat tttgactatt caaaagtagc accgtttgtc aacgaacaag
     7801 agttagggta catgcaaagc caagtaacag cagcccacaa cgaattacgg gaaggtactg
     7861 gcgcaggaag cgacttccgc ggctggatcg atttaccaac gaactatgac aaagaagaat
     7921 ttgcacgtat caaagaagca gctaaaaaaa tccaatctga ttctgaagta ttagttgtta
     7981 tcggtatcgg tggttcttat ttaggcgctc gtgcagcgat cgacttcttg aatcacacat
     8041 tcttcaattt attagatagc aacacaagaa aagcaccaca aatcttcttt gccggaaatt
     8101 caatcagctc aacatatatt gctgacttga tcgaagtaat cggtgatcgc gacttttcag
     8161 taaacgttat ttcaaaatct ggaacaacta ctgaaccagc gattgcgttc cgtgtattca
     8221 aagagcttct tgttaagaaa tatggacaag aagaagcaaa caaacgtatc tacgctacaa
     8281 cagataaagc aaaaggtgca gttaaagtag aagcagatgc agaaggttgg gaaactttcg
     8341 tgattcctga tgacatcggc ggacgtttct ctgtattaac tgctgttggt ttgttaccaa
     8401 tcgctgttag tggtgcagat atcgatgcat tgatgcaagg tgccgctgat gcaagcaaag
     8461 catactcaag cgacaaacta gaagaaaacg aagcttacca atacgcagca atgcgcaaca
     8521 ttctttaccg taaaggcaaa gtaactgagt tgttgatcaa ctatgaacca ggaatgcaat
     8581 acttctcaga atggtggaaa caattgtatg gtgaatctga aggaaaagac caaaaaggca
     8641 tctatccttc aagcgcaaac ttctcaactg atttgcactc tttaggacaa ttcatccaag
     8701 aaggacgtcg caatattttt gaaacagttg tgaaggttga aaaacctcgt aaatcaatca
     8761 caattcctga acaagcagaa gatttagacg gtctaggcta cttgcaagga aaagaagtgg
     8821 acttcgtaaa tacaaaagca tttgaaggaa cattgcttgc tcatacagac ggtgacgtgc
     8881 ctaacttgct agtcaaaatt ccagaaatgg atgcttatac attgggttat acaatgtact
     8941 tctttgaaat tgctgtaggt atttcaggtt acttgaatgg aatcaaccca ttcgaccaac
     9001 caggtgtaga agcttacaag aaaaacatgt tcgcacttct aggcaaacca ggctttgaag
     9061 atcttgctaa agaattgaac gaacgcctgt aagataaggg tttttcgcta gatttaaata
     9121 atcagtgata gaaacatgtt cgctttaaaa tgaaaactgg tacccattta ggtactcaaa
     9181 catactgcat cgtttattca gaataagggg ctgtgacaag acgtttgtca cagtcccttg
     9241 tttgtataga aatcgattga ttgccttgct ctttagtttg ttttaggact ttaagaacag
     9301 tgaggctgac ttcgaaggtt aattctgttt ttttgttttc tagaatcagt aagcaaaaaa
     9361 gcactcactt cgagtgcttt tttgcgatat attcttagct taagataggc ctaatttttc
     9421 ttttacagat gagggtacct tatcgctggt aattactttt ttctctatga tccgcttttc
     9481 gcttgctttc aactgcaaga tcgttccttc ggggtaagca gaaccattgg cagagtcacc
     9541 agaagtaatg acatcgaaat ctaactgtct tttttcaccg ttttcagcat aagcatctac
     9601 gttgtattta aaacctcttc caattacttc cccattatct gctttgatat cagtttctgc
     9661 aggcattgga gctttgacta ccgcataata atctttacct acataagtag actgatagta
     9721 gtcccaacct ttccatccta taaaagcaat caatatgata acgatcaacc ctaaaatttt
     9781 tttcatgaaa gatctccttt tttattttta t
//
LOCUS       DBBGRF010000085         9570 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000085 DBBGRF010000000
VERSION     DBBGRF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.086"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..818
                     /locus_tag="ACIZD4_002699"
     CDS             <1..818
                     /locus_tag="ACIZD4_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC5991557.1"
                     /translation="LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYL
                     ECYFSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHR
                     VKETTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIVD
                     RLLSACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETYTTTLRTFKKFLP
                     QIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGKTFLTK"
     gene            938..1138
                     /locus_tag="ACIZD4_002700"
     CDS             938..1138
                     /locus_tag="ACIZD4_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HGC5991558.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1214..1411
                     /locus_tag="ACIZD4_002701"
     CDS             1214..1411
                     /locus_tag="ACIZD4_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991559.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1708..3255)
                     /locus_tag="ACIZD4_002702"
     CDS             complement(1708..3255)
                     /locus_tag="ACIZD4_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HGC5991560.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3339..4142)
                     /locus_tag="ACIZD4_002703"
     CDS             complement(3339..4142)
                     /locus_tag="ACIZD4_002703"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGC5991561.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4145..4927)
                     /gene="phnE"
                     /locus_tag="ACIZD4_002704"
     CDS             complement(4145..4927)
                     /gene="phnE"
                     /locus_tag="ACIZD4_002704"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HGC5991562.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4924..5703)
                     /gene="phnE"
                     /locus_tag="ACIZD4_002705"
     CDS             complement(4924..5703)
                     /gene="phnE"
                     /locus_tag="ACIZD4_002705"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HGC5991563.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5675..6466)
                     /gene="phnC"
                     /locus_tag="ACIZD4_002706"
     CDS             complement(5675..6466)
                     /gene="phnC"
                     /locus_tag="ACIZD4_002706"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HGC5991564.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6527..7456)
                     /locus_tag="ACIZD4_002707"
     CDS             complement(6527..7456)
                     /locus_tag="ACIZD4_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HGC5991565.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7651..8334
                     /locus_tag="ACIZD4_002708"
     CDS             7651..8334
                     /locus_tag="ACIZD4_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HGC5991566.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8495..9538
                     /locus_tag="ACIZD4_002709"
     CDS             8495..9538
                     /locus_tag="ACIZD4_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HGC5991567.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         2931 a         1956 c         1900 g         2783 t
ORIGIN      
        1 ctttgccaaa ggtcttatgc tttgatgaat tcaaatcggt tcgaagtgtt gccagtgcaa
       61 tgagttttat catgatggac ggacaaagcc atgcattatt ggatattgtc gaaaatcgac
      121 gcttgcctta tttagaatgc tatttttctc ggttttcatt agcgactcgt gaagccgttc
      181 aatggattgt tattgatatg tatgcgcctt atgtttcatt ggtgaaaaag cttttcccga
      241 atgctcagtt gatcatcgac cgtttccaca tcgtccaaca tattggcaga accttcttga
      301 atcatcgagt gaaagaaacc acggcacggc ttaaaggaac ttcccactct caacgagggt
      361 tagggaaaaa attgaaacgc tattggaaac tcctacaaaa agaagaagca aagttaaact
      421 acgaaaaaag ggtttggcgt gccagtttta aagattattt gactgaaagt gagattgtcg
      481 atcgactgtt atctgcttgt cccaacctgc gccaaggcta tcagttatac caagacattc
      541 tttatgcggt aaagaaaaga gatcagtcat tatttgagga ctgtttaaac agagaagtca
      601 gcggtcttcc tgaaacctat acaaccactt tacgaacgtt taaaaagttt ctgccacaga
      661 tccaaaatgc gcttcactac agctattcaa atggaccatt ggaatgttta aacaaccaca
      721 tcaaagtatt aaaacgcaat gcgtacggct ttcgcagctt ttacaatttc aaactacgga
      781 tcatgattcg tcatggcaaa acatttttaa ccaaataaac agaacagaaa gagagtttct
      841 tctttctgtt ctgtccaaat tattctaaga tttctcttta ccaacatcat ttgacaaaga
      901 gcctgtattt attactgtcg aggacaatgg catcggcatg attgaagagg aacaaaaaaa
      961 catttgggat cgctattata aagccgatcc gtcaagtaaa aatacaaaga taggcgagtc
     1021 aggtcttgga ttatcaatcg tgaaggaact agtgcgcctg caccacggtt caattgaagt
     1081 gaccagccga aaaaatgaag gaacgacctt cctgatacaa tttccaaaag aaaaataaaa
     1141 ttaccagtaa aaaaccgtgg agagatagct gctattgatt tttgctatgt cttttctttg
     1201 agaggtatcc ggtatggtgg agtgtctgaa aaataaaaaa atggaggcca attttgtgaa
     1261 agctgttatt tctggaagta ttgttttcca agaagaatat cgagatatgg aaaaagattt
     1321 cagtaaaaaa ggcattgaat taattgatta tcctcgctca tgtccgatcc tagacaaaga
     1381 gtatccagaa atcttgacga ctttttttta aatatcgcag cagcggattt attttttgta
     1441 tttaatcaag atcggaaagg ggtattaggc tatattggtg ccgcaacttt ttcagaaatg
     1501 aagtattgtc tgatgcaaaa tcttattcat ggaaaaagga tcaaaatagt cttatttaag
     1561 gaaccatcag aggaaaattt tttgttttga tgaggtagat cgctggctaa agaatggctg
     1621 gatggaaatc agacagccta acaatttggc ataacaaagg tgtgggcaaa aaactgctca
     1681 cacctttttg aattttttat ttatatacta caaaatcact tgaaaattat gattcacttt
     1741 tgcttcgatg cgtgggtgaa tattcaaata gtcggcaatt aattcggtca tgtcgatttg
     1801 gatttctcgg acaattttct ccgcaccaaa catcgcataa tttcctccgc cgattgcccg
     1861 atattgattt gtcaccactt ccagcatttg ttgcggaaga acggggtgac ctttaaaacg
     1921 aagttcggta atccgttgtc caacaggctg tttcatatca atagtgtact gaatcccttc
     1981 atacatgtca taattgtagt actggggctt aggctgaata aaggctggat tgaatacgat
     2041 ttggttattt tctacagcta aataatttgc ggtctgctcc aacgccgctc tcaaatctgc
     2101 accatttatt tgaatcactg ccagagtatt cggataaata tagttggtga tgacgtcccg
     2161 catcgtgatc gtctcaccaa agccttttcc ttcattattg aataacgcag ttccagaaat
     2221 ctctgagccg ctggcaaata attgtacacg attaataaac tctacatagg gatgttcctc
     2281 aagacgagcc tgcatcggat cattaatacg catatttccg ttcactttac ctaagggttg
     2341 atccaaccat ttctctagtt tttcttctac cggtacgatc gctgcaagaa tttctggatc
     2401 aggctctgat ttttcaactg agtgtaaagc aacctggtga tctgtaacaa ccacttgccc
     2461 ctcttttttc tcgacggtaa gacgaatttc accgatgaac tcgccacgat agcctggttg
     2521 aacaacggga actccatgaa ccgtttcagc aattttccgg tgctgatgac cggtgaaaag
     2581 ggcgtcaatg ccttcaacct gctgcaatag ctcgtagcct tcattctctc cagttagcgc
     2641 ttctgtgtcc tcaccggtta acaagtcttt ttcaaatccg ccgtggtaac taacgattac
     2701 caagtctgct tgtttcctta atagaggaac atattctttt gctgtttcga cgatactctt
     2761 aaacgtaatt cctgctaagg tttctggctt ttcccagtga ggaatgtatt gtgtcgttaa
     2821 tcccaagata gcaattttta cacccacctt ttcgataatc ttataggcgt ttccaaagta
     2881 tggttggtca tttttgttca ccatattggc tcctaatata ggcgcttgat aattcttaat
     2941 cgcttcctcg agataatcca caccatagtt aaactcatga tttcccaaca cttgaacatc
     3001 atagctcatt tggttaatca agtctgtaag ctctttggct gaaccatatt ctttagcaag
     3061 ataataactc aaaggagacc cttggatgaa atcaccattt tcgatcgtaa ttaccggtcc
     3121 atctgctttt gcccgtaatt ccttcagttt cgacgatact ttagccgttc ctaaggccag
     3181 atcggttctg ccggaatagt ctgttggtga aacatagcca tgcatatcac ttgtctctaa
     3241 aaacgtaatg ttcattctgc gtgctccttt agctgactca aaatagaaaa accgaagcgt
     3301 attcagctgt tcggtctctt tttttgattt ataatgcctt aatccttcat ttgaagtgtt
     3361 tttaaaatgt tgcctggaat aaagttttct gttgtctggc gaacaatcct tccttgatcg
     3421 agatgataaa ggttataccc atgacgttct tcaaagcgta cgaagccatc gccttcatct
     3481 tcaccaacaa aggacatact cgatacagta aaatagggga tcccattaat ttcatcagta
     3541 aatgtgtgat gggtatgacc gtttaggata cagcgaatat cgtaaggtgc gattagcttc
     3601 aagaaacgtt cggtaccagg ccattttggt atactgcttt ggtgagacag tagatgatga
     3661 tgggtgacca agaaaatcgg ttggtctttt tcttgctcta aggctttttt cagccattga
     3721 aattgctgat cgtccactat accatctgcg tatccatagc ttgaattatc aaaggaaatc
     3781 actgtaaact caggatattt gactatctgg ttgtacgggg cagaagaggc ggcttcatcg
     3841 caccagccta cccaaaaatg ttctttgata tcgtgattgc ctagagtaac aagaatcgtc
     3901 gtttctccta gcgcattttc cagccaagtc ttcaagtatc gataatcgtc tatttcgcca
     3961 tcttcggtta aatctccgct gataatcaca aggtccaagg gtgtttgctg caggagatga
     4021 tgaatgcatt gctccagagg gataagggga ttctgcatcg tagccagcat tcccttatag
     4081 ccttcttcac aagcctcata ctctctgcga aagtgtatat ctgatatatg caatatattc
     4141 attcttatct caatctcttt cttataattc cggttatttg atctaaaata aacacggtta
     4201 cgactacgcc aatcaaaata atactcactt tgctccaaga ccgagtttga atcgcgaata
     4261 tcaatggagc accgattccg ccagcgccaa ctaagcctaa ggtagccgca ctacgaaccg
     4321 ctatttcaaa atgatttaat gctaaagaac aataaatcgg catcaaatag gggatgcgaa
     4381 caaagaaaat cgtttgccaa aaatttgctc ctaccgcatg catttcttca acaagtcgct
     4441 catccatcgc ttccatttct tctgtaaaaa gtttgccaag cattccgatc tgatggacgc
     4501 caatcgccat aacaccagca aaggggccag gtccgacgac tttcacaaaa ataattgcaa
     4561 aaactagttc aggaaaagct cgtaaaacat tacagataag cttgccaatt tttgttaccc
     4621 atggatgtgc ttgccagagg ttaaccgcac tgatcaaggt aatgggaatc gctaataccg
     4681 tagcgatcat tgtccctaaa caggcgattc caatggttaa taatagcaaa ctaatcaaat
     4741 cctcgccgct gccatcatat agaaactgcc aatcaggctg acctaaccct ctcaaaacgt
     4801 ccattcccat ggaaggagag aaggtgctta atccagagta atccagagta gcggccgaca
     4861 aaataacgag aatcactaaa gcaactaatg ataaaagggt tcttctgttc atttcacgaa
     4921 gcatcataac agggacctcc tgacacgttc acttaattta tcaacgatcg cgacagttac
     4981 taggatcgtt agaataatga ttgaaactcg ttcataattc aaaagcgcaa gtgaggaatt
     5041 tagaataacg ccaataccac cagctccgac atatccaagg acagtagaag cacgaacatt
     5101 cacctcaaac gcgtaaaaag catagctcgc aaactgactc aaaacttgtg gagcgatcga
     5161 ccaaatagcg atttgcattt tatttgctcc aacagccgca gcggcttcaa tcgggccaaa
     5221 gtcaatggtt tcaattgctt gaaacattaa ttgtgacacc ataccaaaag taaagacagc
     5281 gatagtcaac acgccagtcg cttcaccaat tccaaacaca gcaacaaaaa gcgcggctaa
     5341 aagcagggta gggatggtcc gtactaaacc taaaagaaaa cgaaagatgg tagaaagaag
     5401 acggttttct gtcactacag tggtcgctaa aaaactaaca gggatcgcta aaattaagcc
     5461 aatgaccgtt ccaagcaaag acatttgaag tgttttcacc ataggctcga ctaatttagg
     5521 taaatagcta aagtctggat gaatgaagcg tgataaaaag acagtcattt gattggagtt
     5581 ttgaaaaacc tgagaaaaat cagctgacgt gatccaggca cttccttgaa aacaaacaat
     5641 taagaacaga agaataagca ggtgtttata ccatttaaag tgaacggttt ctttcaagct
     5701 catcgatttc gcctgccttt tcttcaaaga ttgcattgcc ataaatttgc tctaagcgtt
     5761 catcggttaa gtcgtctgga cgaccatcaa agacaacctg agcagctttt aacgcgagca
     5821 cacgcgtaga aaactcacga gccagaggga ctgaatgcag attgacaatg actgttttat
     5881 ccatcgtttg attgatattt tttaggtcca tcataacctt ttgagtcgtg attggatcta
     5941 atgatgcaac gggttcatcc gctaaaataa tgggggcttg ctgcacgagt gctcgcgcaa
     6001 tggatactcg ctgttgttgc ccaccactga gctcatcact gcgtgtctgc aatttatcag
     6061 acaaaccaac tttttccagt gcttcctttg tctgctggta gtcttccttc gtaaaaagac
     6121 ctaaaatact tttccaagtg gagtaatagc ccaaacgtcc agatagcaca tttttctgaa
     6181 ccgtactacg ctttaccaga ttgaagcttt gcgagattag accaatctgg cggcgaatct
     6241 gtcgcagctc ttttttattc gcttttgtaa tagaggttcc attaatgcga atatctcctt
     6301 tggtggtttc tgccaagcga ttgatactgc gcagcagagt gctctttcca gcaccactca
     6361 accctatgat ggaaacaaat tctccatctt caattgttaa gtcaatatcc ttcaagccaa
     6421 caacgccatt gggatagacc ttcgaaacat tgtcaaaaat aatcattatc cttctccatt
     6481 tttttaagtg taagcaaaaa aaagcttgct gacacttact gatgttttat tctgctgctt
     6541 ttttcgtgta gtctctgatc gtgtcatagg cagaatcagc agcttcttca tagccctgat
     6601 gcccccacaa agccattgct tctttgccat ctttatcatc cttcatattt aagaaggtct
     6661 ctttaatttt cgcttttaaa tcttttgaca tgtcaggctg tacagcgatt gcgtcattcg
     6721 gaatatcgcc ttttgtcagg tacaggactt ttaaatcctt aaataaatca ttatctggga
     6781 aattcgaagc aaaaacattt cgcgcgcctt caaaaacaaa cgccgcatcc atttgcttgt
     6841 tcaacactgc ggtaatctca ctcggaatat cattcacagt ggtcatcttt gtatctgcag
     6901 taggatcaat cccagcatct ttcaattcag cgacaggata gatgtagccg ctagcagagt
     6961 taggacttaa ggttgcgata ttttttcctt ttaaatcagt taacttattc aatccgctat
     7021 cggcacgaac caatacttct cctttaaagg tgttcgtaag tttgtccttt aatggcaagc
     7081 cagtttcttg atcataatcg ccgagctgag aagtcaggat tgcatctgca gctccagcat
     7141 cctttgcttg aacataggct gcaggcggca taattccgac atcgacttga ccagaagaca
     7201 tcgcttcgac gatcgttgaa taatcagtag ctaacgtcac ttctacctca cgatctaact
     7261 ttttcgataa atacttagca aatggttttg cttttgcctc catactacca tcattgtttg
     7321 ttggaacgaa ttgaacaact aatttttctt tgctctcttt ttctgagctg ctacttgtat
     7381 tcccagaacc gcaggccgcc aaagtggtca ataacatgac tccgatgaac ccttttgcta
     7441 actgtttgaa ctgcattttt ctcctcctgt tggatataat ttctaatacg tctaaatcat
     7501 agcagggaat caaaatcaat gaagtgacgc acgtcctatt ttacacaact tttacataca
     7561 atttacaaac aattataaat aattattcgt attgagccga aaaacaatct aagctataat
     7621 aaagaaaaac ttcttagagg tgacgatttc atgaaaaaaa tccatgatac gaagcaatta
     7681 actgcttacg ttgagaagca caacctgcag gattatatgg attcagatat attggcaatg
     7741 gcttctttac ttttttttga aaaggaagag cacctcattc aaacgggaaa aacctcagat
     7801 tatttgtatt ttttagtgga tgggacggta atggtgtact cgtattcttc tgatacacaa
     7861 aatatttgca tcgattacgc aaagcccgct acaccactcg gcgaagcctc ttcattgtgg
     7921 gaattatcgc cgaaaagcag cgttaaagca gtgactaagt gcatctgtat cagcattccg
     7981 ctaaatcaat atcgaacaca gcttcaaaaa gatgttcgct ttttgcagaa tatttgccag
     8041 ttactaagtt atcgtttaaa ttccgggata aatttggcga actcactgac agaacctgtt
     8101 gaaactcgtt tagcaaagtt tattttgacc catcacgaaa acgaacgttt ctcatttcgg
     8161 ttaaccacct gcgcctcaat cttaaatgtc agttatcgac atcttttacg aacaatcacg
     8221 aattttcgtg aggagaatat tatcgaaaag aaaaagaatt attacttgat tcatgatatc
     8281 gaagctttag aggacttagc tgagaatata agtagtccag taaaagcaga ataacagcta
     8341 taaaaaaaca gcagtcagaa gtgattgctg gttttttgat agtggagaaa ttgggaaacg
     8401 gaaaatcttc gttgaagagt agtgttctat atattggtat gctatacttt taaaagttca
     8461 atgtgtcaag acacataaaa aggggagaaa aattttgaag aaaatacttg tttcattgtt
     8521 gtttttggtg tcattagtaa cgttagtcgg ctgtagtcag tctcaggggg agaagcaaag
     8581 tgaaaaagag aaaagtaaaa tcgctttggt tcttggattt ggcggggttg atgaccgctc
     8641 cttcaatcaa gctggctggg aaggattaga ggcttgggga aaagagaaaa agctgacagc
     8701 aaaaaaagat tttacgtata tagaaacgaa caatccagag gataacagta ccaatatcga
     8761 tcaggcaatc agaaacggct ttaccaccat tattagcttg agctacttgc aagcagagga
     8821 actggaaaat gctgctaaag ataatccaaa gttgaaattt gccttggtag atggtgagat
     8881 tactgggaaa aagaatatct catcagcaac ctttaaagat caagaaagtg cgtatttagc
     8941 aggactagct gccgcatata cgacaaaaag tgatcaagta ggctttattg gtggaatgga
     9001 agggcccgtg atccaacgtt tccaaagcgg atttgaagct ggcgttaagg caggggccac
     9061 agcactgaac aaggaaatta ctgttaacgt acaatatgct gcatcctatg attcgctaga
     9121 taaaggaaaa gctattgctg cttctatgta caaagaggga gtcgatattc tttatcaggc
     9181 ggcaggaagt actggagctg gggtgttcca agaagcaaaa gcccgcaatg aaaacgacta
     9241 tagcagaaaa gtatgggtga ttggtgtaga tcgcgatcaa gcggatgaag gggattataa
     9301 aatggagaac ggcgagacag ggaatttcac gttgacttct acaaagaaaa atgtcggtgc
     9361 agaagtcaaa gaatttgcag aaacttctca taacgataaa tttcctggcg gcaagcattt
     9421 gacctttggt ttgaaagaag aaggggtaga tctgacaaaa ggacaattat cagaggaagc
     9481 ctatcaggca gtttcagacg caaaagagaa aatcatcagt ggtgatttca gactgtagac
     9541 aaagtccatt ttatggatga tgtctacagt
//
LOCUS       DBBGRF010000086         8536 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000086 DBBGRF010000000
VERSION     DBBGRF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.087"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(132..1085)
                     /gene="menA"
                     /locus_tag="ACIZD4_002710"
     CDS             complement(132..1085)
                     /gene="menA"
                     /locus_tag="ACIZD4_002710"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HGC5991568.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1098..2201)
                     /locus_tag="ACIZD4_002711"
     CDS             complement(1098..2201)
                     /locus_tag="ACIZD4_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGC5991569.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2291..3226)
                     /gene="pplA"
                     /locus_tag="ACIZD4_002712"
     CDS             complement(2291..3226)
                     /gene="pplA"
                     /locus_tag="ACIZD4_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HGC5991570.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3528..5462
                     /locus_tag="ACIZD4_002713"
     CDS             3528..5462
                     /locus_tag="ACIZD4_002713"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGC5991571.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGKSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5919..6335
                     /locus_tag="ACIZD4_002714"
     CDS             5919..6335
                     /locus_tag="ACIZD4_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HGC5991572.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6349..6915
                     /locus_tag="ACIZD4_002715"
     CDS             6349..6915
                     /locus_tag="ACIZD4_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HGC5991573.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6938..7924
                     /locus_tag="ACIZD4_002716"
     CDS             6938..7924
                     /locus_tag="ACIZD4_002716"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGC5991574.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8079..>8536)
                     /gene="scm"
                     /locus_tag="ACIZD4_002717"
     CDS             complement(8079..>8536)
                     /gene="scm"
                     /locus_tag="ACIZD4_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HGC5991575.1"
                     /translation="SDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTD
                     TSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTN
                     KTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         2517 a         1642 c         1732 g         2645 t
ORIGIN      
        1 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat
       61 aaggagctat ttttatttgg ctgttcttat tacttgatgc agggcagttt tttcacaacc
      121 tcttcatgct gttaaatggc ttgcataatg attgttagta atagccccaa tacataactg
      181 gcattgaata agaccatatt tttgatggaa tagctgaaac tgataggctg gggtaacgtt
      241 tgcttgaatt gatccaaatg cttcttcaca attggcaagg tcaagaaggt gaccaagatc
      301 ggccattcat agataccgct caacaacccc attaaaatca cgaaatagca agcatacatc
      361 aatagctgga ataagactgt tcccgcagga cgtccgatat aaaaaactag tgtatagcga
      421 tgattttcaa tatcacggtc aagatcccgc aaattattag ccaacatgat attggcaatc
      481 gtaaacacca agggtaagga agctaatacg attgctgcta tagcccaaag atttcctacc
      541 aaagcaaatt gtccagatga aaagttgact gtcagatcat agacatctga accgaatgta
      601 ttgacataaa cgaccatggc aaaaattcca aggcccatag tcaccccact gaaaatttcc
      661 cctaaaggca ttcgagataa aggaatcggt ccgaatgtat agaatactcc aataaaacaa
      721 cagataaatc ccatcaaaag taaaagccaa cccgtattga tcgttagaat aacgccgata
      781 acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa tcaatacagg agatagattt
      841 ctgcggccaa tgacattttc ttcatactta tatacttcag aatgagcctt ttcataatcc
      901 atgtaattat tgatagcggt agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa
      961 aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag agaataatac ccctaccgca
     1021 aaaggaaata cactagccac ctttgttcgt atttcaacta cttctaaaaa gatttttagt
     1081 gtcatggttc gtactcctta ttttagttca gaacggtcac ccatcgtgta atgggagtcc
     1141 tccgataatt tgaaggtgtc tttgattgga tcggtcacat atactttatc gtcttttgtc
     1201 acgaagatcg cttccgtccc gttattcaat tcgctttcga cgtattccag tccttttttc
     1261 acacccattg aaaagactgc tgtagacaac ccgtcaccat caattgattt atctgttatg
     1321 atcgtgacac ttgcgatatc attgtcgaac ggataacccg tttttggatc aaacaaatga
     1381 tggtattttt tgccatctac ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt
     1441 ttgttccgtt ctttaataga acctaaaaca gatccgcgag ccatgttcgg atcttggatg
     1501 ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc ctaagacata gacattaccg
     1561 cccaagtcaa cgatggcagt ggtcactcct tgttttttca agactttcac tacttcgtcc
     1621 gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca ttcctttttc ttttagataa
     1681 acagtttttt ctttgtcatt tagttcgatc ttatgataat ccactaattt caatgcctga
     1741 tcgatttctt cttgggaagg ttttctggcg tcatcaaaac cgattcgcca taattgtgtg
     1801 attgcaccaa tcgccatatc gaatccgcct tgagaatctt ggctatattc gtaggcccgc
     1861 ttgactaacg tgtagacgtc atcagaaact tttactggtt tgatcccagc ttgctcattc
     1921 acttcatcga tctcagaacc tttttgattg atcgtgattt tatcaccaag ttcttttact
     1981 cgatcgaagg caggtttcaa tgctgattct ttgccttcat catacacacg gatacgaacg
     2041 taagtcccta acaagaactg ttcatcagaa tatggatctt tcaatatctt ggtagctgct
     2101 gaactttcag tggttgtttt atttgctgag ttgctgcagc cagttagcac cataaaagag
     2161 atgcccagtg tgattaagga aaatagtagt tttttccgca tctttttcct ctcttcattt
     2221 tgaaaggtga gacgactgcc taatctggct atcgtcccac cctccaactt ttattagtat
     2281 gattatgtga ttatttttct gttacgatat tatctacttc gattgtttga gtgtcgcctt
     2341 tttcagctgc attcactaat tgttgtgcgt acatgatgaa tgaatgtgag ctgtgtgtag
     2401 cacctgtaac aacttctaca ttagcaggtg agccatcttc ttcgcccatt gctttgacga
     2461 attcgtcgtt cagagtaggg atgtaagttt ttggttctgt accgcttttt gctttcatat
     2521 tttcattata ttctgtatca tcttgttttg atttaccgtc tttgtcgata taatcaaagt
     2581 ttgattcagt tactttgccg ccagcaactg tcatttcgaa ttgcacacgg tagccgttag
     2641 agtagttctt ttcttcaagc ttgtaagtgc cgtctttcaa atcagcacca ttgtcgattt
     2701 cgattgtatc tgtgttacca gcttgagcag cttggatcaa ttgttgtgcg tagttttgga
     2761 agctttcaga tgagtgagta gctccagtta cgacttccac accgcttgcg ctttgtgctt
     2821 ttaagaattg gtcattcaac tcaggaatgt atttttctgg gtttgtgcca gattttgctt
     2881 ccatgttttt gttgtattct gcatcttttg tttttgattc gccgttttca ttgacgttat
     2941 catattttga ttcagtgatt ttgccgtctt ttacaaccat ttcaaagact gcacggtaac
     3001 catttgaata atttttttct tctaatttat atgtgccgtc ttgcaaatct ccgccagcta
     3061 caacttttgc agatgattct gttgtgcttt ttgcagtcga agattgtgct gtagatgatt
     3121 cagaagaaga gtttgagctt ccgttgtcat ctgcgccgca agcgcctaac actagagctg
     3181 aaaatgctaa tacggcaaat ccagttacaa aacgtttttt cttcatttta ataccccacc
     3241 attccatttc tagtccacaa tttttctttg tgattcatta tacattctaa tctttttagc
     3301 ctataagtca actatttttg ataaataacc catgtaatat ttcaaacgtt ttctttcagc
     3361 aaatttcgtg aaaaaacgct ttattttaaa atttgaaaaa aatccaaaag gagttagaca
     3421 aaagaacaga acatctatat aatatatgga gattgtgtaa taagtatcaa actaaaagaa
     3481 ttatcatata ttcattatat agatagtcta taaggagcgg atgatcaatg gcaaagcaaa
     3541 atattgtcgt tgtaggagca ggatatgccg gtgtttcagc tacaaaatac ttggcaaaga
     3601 aactgaaaaa agaagatgta gcaattactc tgatcgatcg tcattcgtac catactatga
     3661 tgaccgagtt gcatgaagta gctggcggac gtgtagaacc agaagcaatc caatacgatc
     3721 tgcagcattt gtttgctcgt caaaagaatg tacaacttgt cacagacact gtaatcggta
     3781 tcgataaaga acgaaaaatc gtcaagacca aattaggttc ctatcctttt gatcagctga
     3841 tccttggaat gggcggagag ccgaatgact ttggtacacc tggtgtcaaa gcacacggat
     3901 tcaccctttg gtcatttgaa gattctgtaa ggattcggga acatattgag aagacagtag
     3961 caaaagctgc attggaacca gatgatgaac tgcgtaaagc catgctgact ttcgttgtct
     4021 gtggttctgg atttaccggt attgaaatga ttggggaact gatcgactgg aaaaatcgcc
     4081 tagccaaaga ttataaatta gatccaaacg aaatcacact gatggtcgta gaggcaatgc
     4141 cgacgatctt gaatatgttg gatcgaaatg atgctgcaaa agctgaacgc tatttgcgta
     4201 agcacaacgt ggaattatta ttgaatgcac caatcgtaga agtggctgct gatcatatca
     4261 aattgaaaga cggacgcaac attccgactc acacactgat ttggacagct ggtgtcaaag
     4321 gaacttctga cgctgctgac tttggattag aatcagcacg cggacagcgg ttgatcgcca
     4381 atgaatatat gcaggcaaaa ggctacgaag ataaaaacat ctatatcatt ggtgatttag
     4441 tcttttatga agaattccca ggaacaccga caccgcagat cgttcaagct gctgaacaaa
     4501 caggacacac agccgcagcg aatatcgtgg cttcgatcaa aggcggagaa aagcataaat
     4561 ttaaaggaaa ctatcaagga tttatggttt ctattggtgc caaatggggg gtagctaacc
     4621 tatttgataa gatccattta agcggatttt tagctatcgt aatgaaacat atcgtgaatt
     4681 tgaaatactt ctttgatatt cgttctggtt attatatgtt ccaatattta atgcatgagt
     4741 ttttccatat caaagatgat cgcaacgtga ctcgaggaca ttcttctcgt tacggcaatg
     4801 tcttatggag tgtgccactt cgtattttct atggtttagt ttggttcgtt gaagcttcca
     4861 aaaaaatcat tgggaatggt gaagtgttca aaccaagtac ttggtttggt gaaggatcat
     4921 ggttcactgg aaaaagtgtg ttcccttgga catgggaata caatgtaaca gatgttgcca
     4981 gtggtgcttc tgctgctggt gatgcaacca cagctgccag cggagcaggg gcaagtgccg
     5041 gagaagcagc gactcaagct gcacattttg gtttgagtta tgcatacggt gaagaaccaa
     5101 tggctgtgat tgagaagtca ccagactggt tcacaaagat catgcaagtg atcatgccaa
     5161 acaatgatgt agcaatgttc ttccaaaaat tcatggtatt ctttgaaatt gccttggcat
     5221 tagcattgat tgctggatta ttcacatggc tatgcagtgc gacaacgatt gtattggtga
     5281 tcacgttctg cttatcaggc atgttttact gggtaaacat ttggttcatt tttgttgctt
     5341 tcgcattgat gaacggttcc ggacgtgcga ttgggttgga tcgctgggta attccatggc
     5401 tacaacgtac actaggtaat tggtggtacg gtagaccaag ttcccagtac ggcaagaaat
     5461 aaatagataa agaacgttat ttgaatgcaa gatttcaata gaaaggggct gagacaaacc
     5521 gtcacagcct cctttttatg taaaattaaa ggaataagat gcccgagata agcctccatg
     5581 agcaagacac aggtgtcaca acctctgtta caacctcttg ttataaacgg tgttccagaa
     5641 gtagcttctt cgaaaaataa gccgaaattt cacaaaaact tgaaaagtaa ttttcgtaaa
     5701 ttccttctta tttcttgaag ttgcccactt ctgtcacaac ctcttgttat aaacggtgtt
     5761 ccacctgctg cttctcggta ataagcccaa agaattagaa aacatggaaa gctgttttct
     5821 attcttcgtt cttattactc aaagcaagac acaggtgtca caacctcttg tttttatgct
     5881 aaaattgggt gagttaatct ggaaaaagga gaacaaaaat gagccttaaa gaatttgctg
     5941 aaaaaagtct gctcaaacct tgggatgttt ttattatttt gcttttgact gttctttctt
     6001 ttttaccagt catgattttt ggtcttcagc aaaacaccgc aacagcagaa aaagaagcgg
     6061 tactgcgtgt ggatggcaca gaaatcaaaa cattcccttt gatggctgga gaagagagca
     6121 acacatatac ttacaaagat gaacacggag attataactt gatcgagata gatggcgatc
     6181 gagtacggat aaaagaagca gattgcgatg accagatctg cgtacgtcga ggctgggcaa
     6241 cgaaaaatgg cgaaaccatc gtctgtttgc cacataaatt agtgatcgaa gtccgttcaa
     6301 cagatggagg tgacgaagac agtctgattt attagacctt tacacaccat gagtaaatta
     6361 caaaaaatga tttatatttc gctacttgtt gcacaaggag tgatcattgg tttattggaa
     6421 aatatgatcc cttatccttt ttcttttgcg cctggtgcaa aactaggctt agccaatcta
     6481 atcacgatcg ttgccatttt taccatgaaa aaacaagaca gcttcttact actttggcta
     6541 cgactattcc tgactacttt gctaggcgga acgatttcca cattccttta tagtatgagt
     6601 ggtgctttgc ttagttattt tggaatgtta ttggtcaagc aattaggacc aaaacgtgtc
     6661 agtatcatcg gaattagtgc ggccggcggt ttcatgcata atgtcggaca gcttttgatg
     6721 gcttctttca ttgcacaatc atggacagtc atgttgtact tgccagtcct ttcagtttta
     6781 gggattttat cagggattgc aatcgggatc gcagcgaatt atcttttacg acatgtgcag
     6841 acacttcaac gattccaaaa agattatgag cagggaacca aacaaaaatg gagcccaatg
     6901 tttaccaaaa aataatcgtc acacaaggag tttttttatg aagctacatc caatgtggga
     6961 aaactatcct gctttaagta aagaattgac agaaacacta aaacggatgg aagaaactgt
     7021 ccgcctgaaa aacaaacctg tcgaacaagc aatcaaagaa acgatccatg ccggcggaaa
     7081 gctgttgcgt cctgcctatc agctattgtt ctcacaattt ggaccagagc aagatcgaga
     7141 caaagccatc gctttggcag cttctatcga aatgctccat acggccacac tgatccatga
     7201 tgatatcgtt gatgaagcgg atctgcgacg tggtcagcct aatatccgta gtcagtttgg
     7261 taatgtcgtt tctgtctatg caggagacta tttatttgtc tgctgtttta aactattgtc
     7321 tgattactcc acttccttga aaagtctcca attgaattct cgcagtatgg aaaaagtatt
     7381 gaatggcgaa ttagggcaga tggatgatcg ctataattat gaactttctg taaaagaata
     7441 tttggaaaat atttcaggta agacagctga actgttccaa ttaagttgtt ctgttggcgc
     7501 ttttgaaagt ggaacaagcg agcgcttcgc aaaaaaagca ggagatatcg gactttctat
     7561 cgggatggcc tttcagatta tcgatgatat tttagattat acaaaagaga gccaggaaat
     7621 cggcaaacct gtactagaag acatgcgtca aggggtctat tctttaccgt tgatctactc
     7681 tttgcaaaaa aacaaaccaa agctactacc ttatttagag aagaaagcgg caatgacaga
     7741 agaagatgtc gacgccgtac gcaaaatcgt tgaacataca ggaggcgtgg aagaagctag
     7801 gaagttagcg gcctcttaca cagaaaaggc tttgaaggaa ataaagaaat tacctgccac
     7861 ctctcttcga acaaaagaga atctcttttc ccttacccaa ctgattttgg atcgcaaaga
     7921 ctgaataggg aaaggttcga tacgtaaata aatttctcag aaggaaatct acgtgttttt
     7981 tgacaaattg aattgtagtt cttgtattta tgataaaaag caaaaataaa gagcaacgtc
     8041 cgttagcgac gttgctcttt tttatcttga atattttttt accttttcga tttcttataa
     8101 ctcataaaag tgattcttaa accgattaca agtaatataa cgcctgcgag tgttatccaa
     8161 ttattcgatt gacttccagt tttaggaagt gctctttttg atttgtttcc attgtcattg
     8221 cttgttttat tagttaagtt aaagttcgtc ctgttatccg aacttgtttt tgagaaggag
     8281 acacttgcat gacgtgtatc gcttgtggta gacgacgtgt ctgtactatc gcttgaagtt
     8341 gatgaatctg agctatcact tgtggtagag gatgtatctg tactgtcact tgaagctgac
     8401 gtgtccgtgc tatcacttgt agtggtagat gaatctgagc tatcacttgt ggtagaggta
     8461 gtatctgtac tgtcacttga agctgacgtg tccgtgctat cacttgtggt agaggtagta
     8521 tctgtactgt cacttg
//
LOCUS       DBBGRF010000087         8494 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000087 DBBGRF010000000
VERSION     DBBGRF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.088"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..149)
                     /locus_tag="ACIZD4_002718"
     CDS             complement(<1..149)
                     /locus_tag="ACIZD4_002718"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991576.1"
                     /translation="MENHVLETGMQKITTHASITAKPFFEKRGYKVINEQTVELRGQL
                     FTNFL"
     gene            complement(593..1714)
                     /locus_tag="ACIZD4_002719"
     CDS             complement(593..1714)
                     /locus_tag="ACIZD4_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HGC5991577.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVMDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYKPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="ACIZD4_002720"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="ACIZD4_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HGC5991578.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="ACIZD4_002721"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="ACIZD4_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HGC5991579.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="ACIZD4_002722"
     CDS             complement(4304..5215)
                     /locus_tag="ACIZD4_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HGC5991580.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="ACIZD4_002723"
     CDS             complement(5232..6239)
                     /locus_tag="ACIZD4_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HGC5991581.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="ACIZD4_002724"
     CDS             complement(6236..8365)
                     /locus_tag="ACIZD4_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HGC5991582.1"
                     /translation="MKKKLFRIVGIVFISIVLLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8480)
                     /locus_tag="ACIZD4_002725"
     CDS             complement(8370..8480)
                     /locus_tag="ACIZD4_002725"
                     /inference="COORDINATES: protein motif:HMM:NF024254.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991583.1"
                     /translation="MMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2600 a         1726 c         1485 g         2683 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtttgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccatca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca ataggacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DBBGRF010000088         8292 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000088 DBBGRF010000000
VERSION     DBBGRF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.089"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(45..1513)
                     /locus_tag="ACIZD4_002726"
                     /pseudo
     CDS             complement(45..1513)
                     /locus_tag="ACIZD4_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
     gene            1900..2496
                     /locus_tag="ACIZD4_002727"
     CDS             1900..2496
                     /locus_tag="ACIZD4_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGC5991584.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2554..3036)
                     /locus_tag="ACIZD4_002728"
     CDS             complement(2554..3036)
                     /locus_tag="ACIZD4_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991585.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3142..3339)
                     /locus_tag="ACIZD4_002729"
     CDS             complement(3142..3339)
                     /locus_tag="ACIZD4_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991586.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3634..4392
                     /locus_tag="ACIZD4_002730"
     CDS             3634..4392
                     /locus_tag="ACIZD4_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HGC5991587.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4452..4880
                     /locus_tag="ACIZD4_002731"
     CDS             4452..4880
                     /locus_tag="ACIZD4_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991588.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4926..4998
                     /locus_tag="ACIZD4_002732"
     tRNA            4926..4998
                     /locus_tag="ACIZD4_002732"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4959..4961,aa:Gln,seq:ctg)
     gene            complement(5148..5519)
                     /locus_tag="ACIZD4_002733"
     CDS             complement(5148..5519)
                     /locus_tag="ACIZD4_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HGC5991589.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5734..5919
                     /locus_tag="ACIZD4_002734"
     CDS             5734..5919
                     /locus_tag="ACIZD4_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991590.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6002..6190)
                     /locus_tag="ACIZD4_002735"
     CDS             complement(6002..6190)
                     /locus_tag="ACIZD4_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991591.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6214..6477)
                     /locus_tag="ACIZD4_002736"
     CDS             complement(6214..6477)
                     /locus_tag="ACIZD4_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991592.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6635..6892
                     /locus_tag="ACIZD4_002737"
     CDS             6635..6892
                     /locus_tag="ACIZD4_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HGC5991593.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6963..7154)
                     /locus_tag="ACIZD4_002738"
     CDS             complement(6963..7154)
                     /locus_tag="ACIZD4_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991594.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7295..7615)
                     /locus_tag="ACIZD4_002739"
     CDS             complement(7295..7615)
                     /locus_tag="ACIZD4_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991595.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7638..8072)
                     /locus_tag="ACIZD4_002740"
     CDS             complement(7638..8072)
                     /locus_tag="ACIZD4_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGC5991596.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
BASE COUNT         2629 a         1635 c         1314 g         2714 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaatataaa gctaagatag
      601 atgaaccttg ttcttgtaat gaccagaaaa tgattgctgc aaggaataat gggatataag
      661 cccatactct tggtttttct tcagcagtta catcttttga agtcagcatt ttgataaagt
      721 aatacaacgg taagataatc cccaatacac tgattgtatt gacaaaaaag tcaattgtca
      781 gatgaccagt tagttgtgcc ccgccgaata ctgcagcgat aacaacaagt gcgatgatca
      841 agttacggat gaatccttta cgttcttcag ttgtcaaagg attcggcggt gttgtaccca
      901 ctccgtctaa tgtcttgcgt ccttggatga tgtattgtaa taatccaaag aacatcccaa
      961 tagcagctaa agagaaccct aaatgatagt tatattcttg accgattgta ccaacgatta
     1021 gtggtgctaa taatgcccct aagttgacac ccatgtaaaa aatcgaaaat cctgcatctc
     1081 ttcgcaagtc agtctttgaa taaagatgtc cgaccatgcc agaaacattt ggtttcaaaa
     1141 aggcggttcc gataataatc aatgccatcg aaacaaacaa tgtacttaca ccaaatggta
     1201 aagccaagac gatgtggcca agcataatga aaactccacc gaagaataca gtgcgttttg
     1261 ctcctaacac tcggtcagat acccatccgc cgacgatact agacatgtag atcaaagatc
     1321 cgtagatcga catgatagct aatgctgttg ctcgtggtaa tccaagtccc ccgttggcaa
     1381 ctgtatcgta catataatag ataagtaatg cacgcatacc gtaataacta aatcgttccc
     1441 acatctcagt gaagaacaaa gttgacaatc ccttcggctg cccgaagaag cccttgtctt
     1501 gctgtttttc cataatctat accccaattc tttaaatttt cagaaaatat tatacatctt
     1561 taccgaaaaa tttaactaaa aaacttattt aagaaatata aactaatttt ctataaaagc
     1621 aagtaatttt taatggcaat atcataaaaa aaagaagata gagatttaat aattatatat
     1681 cagctgtttt tttcaaataa gcaaaaattc ctaaaacaca acaatgaaag cgataactaa
     1741 gaaaatcctt acataacgat ttttcttatt aaaattgttt tttgaacttc gcttattttt
     1801 tgtgagcata tctgtttact tactttttgt aaggtgctat acttcatttc gtaatcaatt
     1861 aaaaaaatgc aaaacgcaaa tcaaaggaga aattttatta tgacaacttt tactgacact
     1921 ttgaaaaacc gccgttcaat ctatcatcta ggacgtaatg tttcactttc taatgaagaa
     1981 ttaacaactt tgatcaaaga agcaattaaa gaaagcccaa ctgctttcaa tgctcaatca
     2041 acacgcgcag ttatcctttt cggagatgca catgaaaaac tttgggaaat cactgaagaa
     2101 gcacttcgcc cattgactcc agcagaagct ttcccaaata cacaaaacaa attagctggt
     2161 ttcaaaaatg gttatggtac agtattattc ttcaaagata ctgacgtggt aaaaggtcta
     2221 caagaacaat ttgaattata tgcagacaac ttcccagatt ggtcagaaca atcaaacgga
     2281 atcgcaacag ctaatacttg ggtagcatta gttgataaag gattgggcgc aaacttgcaa
     2341 cattacaacc cagttattga cgaagcagtt gcaaaagaat ggaatatccc ttcaaactgg
     2401 aaactacgtt cgcaattagt attcggttca ccagaaacac cggctgggga aaaagaatac
     2461 atgaacgatg ccgatcgctt ccgcgtattt ggataatttt atttgaaata aaaaacagag
     2521 gttgtgacaa acatcttgtc gcaacctctg tttttattct ggatcaatca taatatcaat
     2581 ctctgcctca tcgtttaagc gttgggacaa aaatggaact aattcttcta atgatgcaga
     2641 aaatttcagc atcggtcctc gccatccgtt tcggaaaaaa ttcattttta cgattttaga
     2701 accttttggc tgatataata caattttatt gatctcagaa aaaggaacac cttttttgtc
     2761 aaagctattc aaaacaagtc cttcttctgt gattcctcta ctgtccaaca aaaaactaat
     2821 aaaaatcatt gctgacaaga tcccttttgc caattcatct gctgtaggat gactgatgag
     2881 tgtataccaa atgactagtg acactaagaa gggtatcacc aagtagaccc atcgatttcg
     2941 cacagtccga taaataattt cttttcgaac cagccaaaga aataaaaaca tcacaacaac
     3001 gaataaaaac aatagaaccg taaagaatgt taccatgaca actcgcctcg ctttttcttc
     3061 tccagaaaat aggaaaagaa tactgattta ccttctcaaa gaaattggac ttgcagcacg
     3121 ccgcacgtcc aattgttttc tttattcaaa tgtatcatat tttgcaacaa ccatgcttgc
     3181 tttttcatct aataattctt ggtcctctgc agcacattgg gcaactttga ccacggcgca
     3241 gtttgtcatt tttgatacaa cttcaccaat gaccgttttt gtaaaaccaa ttggtttgca
     3301 tgcatattgt tctcctaaat taatcatttc ttccgtcatc aaaatcctcc taaactgctg
     3361 gaacttttct ccacattacc actgctattt ctttggagat ttaactcatt gatttttatt
     3421 tacagttaaa aatcaacctt acaggcatta tagcgtactg ttttcgtttt cacaattaaa
     3481 acagctgttg tatttagaag aatttttttc aaaaaattaa aacatattcc ttaaaaacta
     3541 attatttcct acatattaaa atataatact tccatttcca ataaaaatac atttataata
     3601 ggaaagataa acagctgaaa agggagattt caaatgaaga aaaaaacgtt caaaaaacta
     3661 ttgtttctag ggggcacagc tgctctttta ttaagcggta caagttatta cctacatatc
     3721 cattctccag aacatacaat gaacactgca caaaaaagtt caacacaaaa aacgaaaaag
     3781 acaaaagaga aagcagaagt tttactagat gttccattag agagccagtt tgattctcct
     3841 tctttagaaa atggctgtga agtcacttcg ctttctatgc ttttatcttt ttatggttat
     3901 gaaacaacta aaaaccagtt agctgagcaa ttggattacg tccctgtttt caatgcagat
     3961 gggactcatg gcgatcctaa tgaaggattt gttggtgata tcagtggcgg agactgggct
     4021 atggtcgtct atgttccccc agttgcctcc cttgctcagc aaatcgtcca aacggattat
     4081 cacacttttc caaaaaccga tgctcaactc gatgatatca aaaaagcact atctaaagga
     4141 aatcctgtct ggacttctgt gactatcaat tttgaagtcc cagatgaaac tgattttatg
     4201 acttggacca caaataatgg agaagtaaga gtcactcctc ttgttcatgc ttgtgtagtc
     4261 actggatatg acaaagaaaa tatttatgtc aacgatccct atggtgtaaa aaatcgagca
     4321 gtaccgatca acgatttttc ggcgattttc actgcaatgg gtggacagat gctaactttg
     4381 gagaaaagct agtaattcaa acaaaaatcc cttatactca agataccaaa cctttgaagg
     4441 gagcgtagat aatggaaaaa ttcacacata aaaaaatgga tccaaatgaa attccgatta
     4501 tttttgtccg tgactgcaag ggaaatgttc aaggtaaagt ctctattaat gagtggaacg
     4561 agcgtcgcag acctgctacc ctcaatgaac tggaaatcaa attgtatcgt caatctcttg
     4621 tttattacgc agatcaagag tacgagaaag ccaccgattt attgaaattt ctaattgctc
     4681 gaacagagta tactcgcttt gaatatattg aacgtttagc aaacatctat catattatga
     4741 atgaacctgt caaagaatat cagttattgg acaccgtctt gtcagtagca gaactgattg
     4801 cccttcctgc tggattagaa aagaaactag tacgccgcct tttacgagta aagcaacaac
     4861 tatccgatca agaaaaataa cttgcgtttt tttaggaaag tgctatgatt attttgttga
     4921 ataaatggga tgtagccaaa ctggtaaggc acttgactct gaatcaagca attgtaggtt
     4981 cgaaccctgc catcccaatt tgatgtgctt gctgaaaaaa tgaaccccct gtaaaagaac
     5041 aatctttttg cagggggatt attgtattat ttttactact tgtatttagt ttacataatt
     5101 aaattatgaa taataaaatc gggcgtattc ttaatacaaa aactgattta cccaataatt
     5161 gctaatgctt tctccggaac tttttctcta ggaacttcct catacgtttc tatgtgtgct
     5221 cctttattgc taattttcaa ataatgattt tcttttaaca cagaaagacc attaaattca
     5281 accgttcgtt ctttcccatt ggcatcagca gctttctgca cataccttgc tgtaccatat
     5341 tcatttactt cctctggttt ttgtgtcttt acatagacct ctcctttttc aactaatgga
     5401 tttagctgat caagtatacc agggatttct ccataacttc cttcagtata atatttcagt
     5461 ccaaatagca aaataccact aatcgccgcc agtccaatca aatatttaat cactttcatc
     5521 tttctacctc cttgttatat attcagtata tgggtcagtt aaagaaattc catccgtccc
     5581 aagttggaga tttttctcct actttagaag cgagaatcga gtgttttttt agtaaaaatg
     5641 atcgttattt gatattattg acgtgtggat aaatcagttt ttctcgtttt gtccatgtaa
     5701 aaaatcatgt tgatagcaaa ggatgtgttc aaaatgaatc aagaagaatt atttcaaaaa
     5761 gtcaaggaaa tgattaagaa cggcaatttc gatggcgcaa aacgatttat cgaagaacat
     5821 aaagaacaat taggacctta taaagagaaa gcccaaaatc ttttaaaaga tgtaaatatc
     5881 gacagtgtca aaaacaaatt taaaaatcta ttcaaataag taaaactttc acttttgtaa
     5941 aatcaaagga ggacaatgct gctgcatcgt cctcctttgg ttcttttctg aatacttcat
     6001 actaaaataa acgtgtcgga tcgtaatgat aagtcacatt gccgttcagt gaggcttttc
     6061 ccaccacata tttacgattc tccaacttca gccacgcttc tcgaaaagcc attaattctt
     6121 ctctttttac atcaatcttt tcgatttttc catcgatcaa atcttgaata agttgttcat
     6181 atggattcat ttttttcctc catctgctgt caatcaataa gttgtaaaaa taggttcata
     6241 tgcttttttg gtatctagat cttctctgac tttgactgtc gtataaataa ttttttctac
     6301 tgggatacta taataacttc cttcaccatt attgaatcgg tgaacgtctt tctttgctaa
     6361 aataccattt attttattcg tcagtacacg ttgttcgaca ctgttactta caacatagta
     6421 aatcacccga atattattga tcaaatgcaa atcgatttct aacactacat gatccatgaa
     6481 aatcccactc cttctttcac tttgattata gcaagtttct cctctaattt caaaatcgat
     6541 acagatttta ccggataaat ccacaaaact gcttgcgcca tttcgcacaa agtgttattt
     6601 tgtatcatgg actttattta tcggaggcaa tagtatgatc gcgatcggtc aatttgtttt
     6661 ttatattcct ttttttatta tgataagcat tcttttctat tacataaaat ggacaaaaaa
     6721 gaagttttca gttttactgg cctctttacc tgctgtatat tttacttatc aaattttttc
     6781 ttttaggcat tgggaaacaa cgtctgtatt aataacacac atcatcgaat tgacgctttc
     6841 agtaattttt cttattattt ggatctattt tttatataag aatcagaatt gaatccctcg
     6901 catgtttaaa aagaaaacga ttaaagatgc agcaaatttc tgccgatctt taatcgtttt
     6961 ttctattctg ttataccaaa aaaatgtttg aatcggtgaa ggatcgttcc ttgttttaat
     7021 tctataaatt cttgtgcgat cgggtacttt tcttccaaat tttctttgtt cttttcgatc
     7081 aggcttttcg cttcttcata ttttttatct gcacatagtg cttttacttc ctgtaatact
     7141 tttcctgctt ccatttgcct caccctcttg ccattttatt gctttaagtt ttatttaagt
     7201 tatacgcatt attctagttt catcccaaat aacctttttt catttttact cctcgaacta
     7261 atcagttttc taaaggctga ttggttcgtc ttttttattt ttcctccatt tcattctgct
     7321 cttctgttaa tttatctaat gctttgattg atgctgcggc tcttgcataa tcatagctgt
     7381 ataattccat aaatttatca ggcagaacaa accacgctgg atgataaccg ttagctgtga
     7441 cagggaatcc tttatcttgt tggttatctc catcccatct cagagcaaca cctttttttc
     7501 ctttccactt tactaaagcg atcgagtatc ccttctttgt ttgtgtgccg tcttcaataa
     7561 ttgctaaaat ttctattttt tcttttggcg cacggacttc ttgaggacga accattttct
     7621 attcctccct tatctcatta cttcacgacc aacacactgc aaggggcatg tgatacgaca
     7681 taagaagcgg tcgatccaac taatgcttgt tgtatagcac cttttcctgt cgctcccata
     7741 acgatcaaat caatattttc ttgtccaggg atgacattgg caatcaaatt tcttggatct
     7801 ccagtttcaa ctattgcgtg gatctcagca atgccgtact ctttggcatc attgattttt
     7861 ttcagcatgg ctacttctgt tctttgtttt tcatctgcat agatttttga aaaggcatag
     7921 gcactatggg tcagctcaac tttgttgatg attgacacga taaataagtg ggcttcattg
     7981 tcctttgcta agtcaagggc ttcagcgaac gctttgatcg attgtcttga tccgtcaact
     8041 gctaccatga tgttctggta tcttttactc attggaaccg cctccttttt cttttattgt
     8101 aacatctcaa gcaaaaatac aaaaaatata cgcaatatgt aaataaaatg atgaacaaaa
     8161 gcaatttctt tcaagttatt tatacatttc ttttctcatc agaacacctg ttctaatccc
     8221 attatttctg cattatgtga aattcctcat catttttcac atcgagcgaa catcattctg
     8281 ttacaaaaaa cg
//
LOCUS       DBBGRF010000089         7870 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000089 DBBGRF010000000
VERSION     DBBGRF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.090"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(51..1391)
                     /locus_tag="ACIZD4_002741"
     CDS             complement(51..1391)
                     /locus_tag="ACIZD4_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HGC5991597.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(1628..3151)
                     /locus_tag="ACIZD4_002742"
     CDS             complement(1628..3151)
                     /locus_tag="ACIZD4_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGC5991598.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(3529..4140)
                     /locus_tag="ACIZD4_002743"
     CDS             complement(3529..4140)
                     /locus_tag="ACIZD4_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGC5991599.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(4263..4388)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(4470..5186)
                     /locus_tag="ACIZD4_002744"
     CDS             complement(4470..5186)
                     /locus_tag="ACIZD4_002744"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGC5991600.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(5192..5761)
                     /gene="scpB"
                     /locus_tag="ACIZD4_002745"
     CDS             complement(5192..5761)
                     /gene="scpB"
                     /locus_tag="ACIZD4_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGC5991601.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(5745..6515)
                     /locus_tag="ACIZD4_002746"
     CDS             complement(5745..6515)
                     /locus_tag="ACIZD4_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGC5991602.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(6512..6883)
                     /locus_tag="ACIZD4_002747"
     CDS             complement(6512..6883)
                     /locus_tag="ACIZD4_002747"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991603.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(6902..7789)
                     /gene="xerD"
                     /locus_tag="ACIZD4_002748"
     CDS             complement(6902..7789)
                     /gene="xerD"
                     /locus_tag="ACIZD4_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGC5991604.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         2247 a         1710 c         1329 g         2584 t
ORIGIN      
        1 aaaaagacgg aatatccatt tgaatatccg ccctttttgt atgtttattt ttatttagca
       61 cataaacgat acacagcttc tgcataaatt tccattgctt tatacatact acttaattcc
      121 catcgttcat tcgcctggtg cataaagtca ggagtatcag ggaacatcgc accgaatgcc
      181 acacactggt tcatcgtacg agcaaaagta gcgccgcctg atacaaacgg ttcagtcatg
      241 tctccagtaa tatcgcgata tgtccccaat agatttttca ctaactcact gtctagtggc
      301 acgtataatg aatcaaggaa gtcaaattct tcataagtca acccatattt ttctgctgtt
      361 ttagttaatt tagctactaa atcatctttc ttgaatgtaa cagggattct catatctaca
      421 ccgatttttg tttgttctgg tgtgatttcc aaacttgcaa agttcatcgt tagctcgccg
      481 gattgttcat cttctgtttt gcccacgaca gcttcaccag ttgcattttc ttgaactaat
      541 tttcctaaga aattgattgg gccaaaatca aatacttctg aaagagcaat tgccagacga
      601 gaaatagcat tcactccttg tgctgcatct ttcgcgtgga tacttttacc aagaacgacg
      661 atgccttcac cttgttcttc gaaatcgaat tcgtgttttt tcaatgcttc ttttacttca
      721 gaaagctttt ctccagagta aggagctgca tcaggaacaa cattcaacgc tcctccagct
      781 tttacagaaa actcgttcgt tcctggtcct gtcaagtaag cttgcaataa gcctttttct
      841 gcataaatta aaggaaattc agcatctggc gcaaatcctt gcgtaattcc ttcttctttt
      901 tcgttatatt tttctaaaca acgccataaa ttttcttcat ctgtaccaaa gataaaacga
      961 atacgtgtct tgaattccac gccagcatca atcaaagctt tgacggcata cattgccgca
     1021 atagaaggac ctttgtcatc ttgggatccg cgaccaacta accagccgtc ttttatagtt
     1081 ggatcgaatg gttttgtttc ccaattattt tcgtcccctg ctggaacaac gtccatatga
     1141 cacaagatac cgaataattc atctccagag ccaatctctg aataaccgta atagccttct
     1201 ggatctttaa atgttctaaa tcctagcttt tcactgattt ccaatacttt atccaaagct
     1261 tcaatcactt ttttaccgaa gggatgtcct tgtcctgaat ctgcttcatc tagtacggaa
     1321 ggaattcgga tcaattcgct caatgattct aatgcttgtt catgatgttg ttctgtcaca
     1381 aattttttca tgatattatc ctcctaatat gttaaaaagg gtcatgtcaa attcctccga
     1441 cacaacctct tcttctcaaa taatgacgtt ttaagcctgc tccatcagca agcagaatgt
     1501 tcttaacaaa tgatgaaaga aaaaacactc actgaatgga gctattgact tgtccacgtg
     1561 cttatcgata gccgtttatc ggtttcttca ttcttatgat agaccttgta cctgtatttg
     1621 tctaggttta gaacattgct gctacaccta ggatcacaca gatggctaca aataatatcg
     1681 caattaattt accggtaaat ttccaccaca ctgaaacatc gaaacgagca attgctacag
     1741 cacccattac gatagcagat gttggtgtaa ttaagtttac taaaccagat gcagattgat
     1801 aagcagtgat tactaaatcc ttaccgacgc cggcaaattc acccataggt cccatgattc
     1861 ccattgttgc agcagctaag ccggaagttg aaggaatcaa gaatgacata gggatataga
     1921 aaataaatgt aataatgatg aatacacttg aagataatga acttaatcct tgttcgcccc
     1981 aatgtaagat ggtgtctgtg attaatccat tgttcataac cacttggata ccacgagcaa
     2041 cagctactac gattgctaca ccgatcaaat cagaagcacc agctaaaaat tcagagacaa
     2101 attcagactc tttcatgcca taagtgattg ctactacgat ggacattact aagaataaca
     2161 tagtaatttc tgggaagtac cagtcaccta atggaagcat gcttttacct agaaccgtac
     2221 ctagtaccgg aaggtttgtt aaccagtttg tcaatgattc aaaaatcgtg aaattcgcat
     2281 tcaaggttgt ccaaggaatc aaactgatga tcatgatacc aaaagtaata aagaacaata
     2341 cattaacatg tttttgtttt ttcgtgatta cttcttgacg accgattgct tcaatatcga
     2401 aatgcttcat atcttcttta cgttggttgt atactaatga ttttgttgga tctttttcga
     2461 tctttgatgc ataacgatac acatatacaa tagaaatagc taacaaaata acgaacatca
     2521 agaatcgaag accaatacct tcacccatcg aaatcccaac agcttgtgaa gctacgcctg
     2581 ttgcaaaagg atttaccgtt gaagctagac agcctacttg agaccctact aatacgattg
     2641 ctacagctac tactgtatca aagcctacag ccatcatgac tgggatcagt aaagcataga
     2701 atggaatcgt ttcttctgcc attccgtaag tagagccgcc taatgcaaat aacagcatca
     2761 atactggaat aagcattttt tcttttcctt tgaatttctt cacaactgaa gcaatcccgg
     2821 catctagtgc ccctgttttg ttgataatac ctaaaaatcc accaacaacc aaaatgaaga
     2881 aagagattgg gattgcagca ggtgtttctt tagttagctc ccccgctggt acacctagca
     2941 tcccattgat tggcgccatg aaaatatccc acagcccttg aggattttgt tgtactcgtt
     3001 catatgatcc agcgacgatg ttgcctgcat cgtctacact atagtgccca gctggtataa
     3061 accaagtaag tacagcgatt actgcaataa taataaataa gaccgtatac gctgaaggca
     3121 tttgaaattt tttctttttt gtttgttcca tcttcttctt cctttctttt ccgttagaga
     3181 caacaatttt ggctctaatg ttattttatc aaaaagagta tcagaacaaa aataataaca
     3241 cgcattttgt aaaacttttg ttcaaaaagt tcgtttttcc ctattccctc ctcttttttc
     3301 aggtttttaa agctttcttc tttttcattg tagcgtttcc ttttttttat aaacaaacat
     3361 tttcgtcttt taaaaggaga agaatttcac atttgcaaag aattgattga tttttatgca
     3421 taaatcaaaa aaatactcaa aacaaacaaa taaaacgttt acattattgc atgtcttgta
     3481 tttttttcca aaaaaaaaga ccaagaaatt tcttgatctt tttgatattt atttgactgc
     3541 tgtatgacgt tgttcgaact gatgttgttt tcgacttaac catggaagaa gttgcgcatg
     3601 cagcactaaa aagacagcac tcacgatgaa tcctttgatc aagttgaaag gaacgatccc
     3661 aatcagtaca tagtttgcta aagacatgcc cagcatctgt gttgcgttca gccctaaaaa
     3721 cattaagtaa agaggcgtaa taacgaaata atttgcgata ctcataaaaa tagttagagc
     3781 gatggttcct gtaatgacac ctaaaaattt gtttcttcct ttatgctgtt tctttacact
     3841 aaagaaataa taaatcggga atgtaaagat cgttgttgat aagaaactag cagtgtctcc
     3901 taccaaatta tccggagaaa aacctgtagt cagcagatgt aatactgaac gcaagaacgc
     3961 tgttgcaact ccggccgctg gaccgaataa gaacatgctg atcaataccg agatatcact
     4021 aaaatcgatc ttcaaaaaac taaaagccgg catgatcgga aaagcaaaat actgtaaaac
     4081 taatgcgatc gcagcaaaca tcgctactgc aaccattttc tgtacacggg tgttcttcat
     4141 ttgaaatcct cctgttagga ctcctcttca gcgaactttt tgacgtttct ctccaaatga
     4201 aaaaactcta ttttccaggg aaaatagagt tagagttatt tgatcaagcg tcgtcaaata
     4261 agctctatct tctttatcca gactatactg tcggtatcgg aatttcaccg attcagctat
     4321 ttttttgcaa aataggtcgt ggactataac caccggtcgg gaatttcacc ctgcccctga
     4381 agacgaacct tatataattt ttgtttacat attcattata catatctatt caaaaaacgc
     4441 aacatctaac acttataaaa agtaagtgtt cattttgagt ggttcagcaa actgctgact
     4501 tcttttttgt tcagttcacg gtaatcccca ggacgtaggc cttgtaaagt cagatctccg
     4561 tatttttcac gttttagttt ttgcacagga agaccaactg cttgaagcat atttttcact
     4621 tgatgattac gtccttcgtg gatcgtcaat tccacgatac tgtggtttgt cttaggatcc
     4681 actgataaaa tttggaattt agctggagat gtttttcgtc cttcgatctt tattcctttt
     4741 gtcaaaggtg caagcatcga ttttgtagcg atccctttta cctttgcaac gtaaacttta
     4801 tccacttcat gttttggatg tgtcaggcgc tgagcaaaat ctccatcatt tgtcagtagc
     4861 aagatccccg aagtatcgta atccagtcga cctacaggat agatacgttc ttttaccatc
     4921 ggcaaaagat ccgtaacaac ttttcttcct ttgtcatctg caacagcaga aataactcct
     4981 ttaggtttgt acaataaata gtaaccgtat tcttcttgat aaattgggac ttcatccact
     5041 tccacagtgt catgtttccc aacttttatc cctaattccc ttacaacttg tccgtttact
     5101 tttacacgtc ctgcaaggat gaattcttct gcttttcgac gagaagtgat gccagcgtgg
     5161 gcaattactt tctgcaatct ctccattaca attattctcc tttattcatt ccatcaaaga
     5221 atagatctgg tgacacgtct tcttcaagtg aaatttccat ttcttgtgta tcaggcagtt
     5281 cttctaatga tttcaaacca aaataatcta agaagtagcc agttgttcca tataatatcg
     5341 gccgacctgg tccttctact ctaccttttt cttcaatcag tttatgggca gctagacgct
     5401 gtaccgctcc tgaaacctga actcctcgaa tctgctcgat ttcagctctt gtgattggct
     5461 gtttataagc gatgattgct aaggtttcga cggcggcttg agataatgtg tttgatgtcc
     5521 cttgcgcata tcgcttaagt aagggagcca gctctttttt agtcgttaat acataatggc
     5581 tttccgtttc aaaaatatgc aaagctgagt gcgagttttg agtgtaagat tcttttaatt
     5641 ctttcactaa acttgtgact tctgcttcgc tgagatttaa cagtccgctt aattcttcat
     5701 tactgatccc ttcctcgcca acaataaaaa gaagggcttc aagttcactt aatttcgtca
     5761 tgttcggtat ctcctactgc tggataaagc ataattgatt catagttttc tttttgttgc
     5821 gcaatgatct gccctttttt catcaattct agcaaagcca taaaagtagt gacaacttca
     5881 cttttagaag gtgactcaaa aaaagaatcg aaagtacagc catgcgcatt tctttttata
     5941 cgctcttcga taaataccat tcgttcttcg atcgttgtgt catcgggcgt gatcgttttt
     6001 tccacttttt gagaaaattt cttacgttct aagattttct gcatggcacg gatcaaatcg
     6061 atttttttga cttgtcctcg cttcaacggc ttttcagcat ccgctaaccc atcgatgttc
     6121 ataggttctt ttgtgtaata aagacttcgt tcctctgctt tttctgtcag tctttcagct
     6181 gcatatttat atttacggta ttctaaaagc tgagtgacca attcttctcg aggatcttct
     6241 tcccataatt cttcatcgtc tgtgccgaat tcttggacag gaagcaatgt cttgcttttg
     6301 attgccatca atgtagcagc catcactaag tattctcctg caacagctag ctcgagtgtt
     6361 ttcattgtat ggatataatt catatattgc tccgtgatcg tagcgatcgg tatatcatat
     6421 atatcgattt ccatttgctg aatcagatga agcagcagat cgagaggacc ctcgaataca
     6481 tctaatttaa tattgatctc cgtcaactca ttcactcttt cttctttttc tttgctagcc
     6541 attttccaat gtaaggctct gtgatttcag ttgcacggat ggagacatcc gggtactttt
     6601 cctgtaattc atctaacatt tgaaagccca tattctcacc gcgataagac ggattcaaag
     6661 aaatgtcatg gatgatcagc tgatcgttcg ttgcccagta aataccaata atcccttgaa
     6721 tgttggttga accttctggc gtaaagaaaa aaagttcata atcgtcttca gattcgtacg
     6781 tatcaatctc cttcaacaaa gaagttttac ctgtcagttt cttatggaaa ctcaatagtc
     6841 ccatagcaat tttacggttt tctttccggt aatgtgttaa catcttctca ccttcctatg
     6901 actaagccct tggaaaatgc tgcttataaa catccgtcat tcttttcttc gtgatatgtg
     6961 tataaatctg agtcgtagag atatccgcgt gacctaacaa ttcctgtact gtccgcaaat
     7021 cagctccatt ttctagcaga tgtgtggcaa agctatgccg cagcgtatgt ggtgttactt
     7081 ctttgtaaat cccagcctct cgtactaact gcttcagatt tttccagatt ccttgccgag
     7141 aaagaccttt cccatgatta ttgacaaata catgcatttc agatgcgtcc tttacaagta
     7201 atggacgtgc ttcgtctaag tagcgttcca gccattggat cgcataatca cctaaaggaa
     7261 tgatccgctc tttatctcct tttccaactg tctgtaccag tccaagagaa agatgaagat
     7321 ctcccaattt caatccaatc aattcactga cgcgcatccc agtagcatac atgacttcca
     7381 agattgcacg atctcttatc cctaacgttt ttgtcgtatc aggtgcttca atcagctttt
     7441 ctacttctgt cagagtcaat gtacttggta atttctgtgc tttcttcggc gtatcgatat
     7501 gttgcatcgg atcatgatca gtgatacgct cttgccgtaa aaactgatgg aatcttctga
     7561 gacttgagat catccgagta acagttgctg tcgctttttt ttcttcatgc aacttctcca
     7621 gaaaacggat gactaaaaag cgatcgacat cctgccatga agcaattttc tgctcctgta
     7681 gaaaatgcaa gtactgttcc aaatcacgtt catagctttg tcgtgtattg gcggacaatc
     7741 cccgttcaat attcaagtag tggagataat cgttgatttg ctctttcata ataatccccc
     7801 tcatgcctct ctatcatatc agataccgct tcattctgat agtctttttc cataatctga
     7861 gcaaagaaaa
//
LOCUS       DBBGRF010000090         7760 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000090 DBBGRF010000000
VERSION     DBBGRF010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.091"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="ACIZD4_002749"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="ACIZD4_002749"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGC5991605.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3285)
                     /locus_tag="ACIZD4_002750"
     CDS             complement(2032..3285)
                     /locus_tag="ACIZD4_002750"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGC5991606.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="ACIZD4_002751"
     CDS             complement(3291..4214)
                     /locus_tag="ACIZD4_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGC5991607.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="ACIZD4_002752"
     CDS             complement(4435..6927)
                     /locus_tag="ACIZD4_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGC5991608.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="ACIZD4_002753"
     CDS             complement(6934..7401)
                     /locus_tag="ACIZD4_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGC5991609.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="ACIZD4_002754"
     tRNA            complement(7537..7610)
                     /locus_tag="ACIZD4_002754"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="ACIZD4_002755"
     tRNA            complement(7668..7741)
                     /locus_tag="ACIZD4_002755"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2161 a         1691 c         1247 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acgaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DBBGRF010000091         7722 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000091 DBBGRF010000000
VERSION     DBBGRF010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.092"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(107..631)
                     /locus_tag="ACIZD4_002756"
     CDS             complement(107..631)
                     /locus_tag="ACIZD4_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGC5991610.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(624..1097)
                     /gene="tsaE"
                     /locus_tag="ACIZD4_002757"
     CDS             complement(624..1097)
                     /gene="tsaE"
                     /locus_tag="ACIZD4_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGC5991611.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1220..2200)
                     /gene="pta"
                     /locus_tag="ACIZD4_002758"
     CDS             complement(1220..2200)
                     /gene="pta"
                     /locus_tag="ACIZD4_002758"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGC5991612.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2353..3033)
                     /locus_tag="ACIZD4_002759"
     CDS             complement(2353..3033)
                     /locus_tag="ACIZD4_002759"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGC5991613.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3159..4028
                     /locus_tag="ACIZD4_002760"
     CDS             3159..4028
                     /locus_tag="ACIZD4_002760"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC5991614.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4054..4569
                     /locus_tag="ACIZD4_002761"
     CDS             4054..4569
                     /locus_tag="ACIZD4_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGC5991615.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4616..5179)
                     /locus_tag="ACIZD4_002762"
     CDS             complement(4616..5179)
                     /locus_tag="ACIZD4_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991616.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5234..5413)
                     /locus_tag="ACIZD4_002763"
     CDS             complement(5234..5413)
                     /locus_tag="ACIZD4_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991617.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5490..5999)
                     /locus_tag="ACIZD4_002764"
     CDS             complement(5490..5999)
                     /locus_tag="ACIZD4_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991618.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6095..6475)
                     /locus_tag="ACIZD4_002765"
     CDS             complement(6095..6475)
                     /locus_tag="ACIZD4_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGC5991619.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6805..7554
                     /gene="pnuC"
                     /locus_tag="ACIZD4_002766"
     CDS             6805..7554
                     /gene="pnuC"
                     /locus_tag="ACIZD4_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGC5991620.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
BASE COUNT         2200 a         1597 c         1369 g         2556 t
ORIGIN      
        1 tttattcaaa aaaaatggac tgcgacacga cttttgtcac agtcccttcg tgtgtttttc
       61 tgccttctca aaaggatgac agtttctcac tcttttccta tttcttctat tcaatcaaat
      121 aactcatttt atatacatct aaaaattcac ctagatctgt tcttgcccct ctaggcatga
      181 ccgcttcgat ttggaagccc atttttcggt aaaggtgtac ggctctttca ttacgaactt
      241 gaacgtcaag ctccaatcga aaaagtacac ccatttcctt cgcccaactg atgatttctt
      301 ctagcataag agtgcctagt cccattcccc aatattcctg cagaatactg ataccgactt
      361 ctcccacgtg agacaaacga aattgactgt ctgccttgac agatgctgtt ccaataatcg
      421 tcccttcata gattgcaagc agcaataaat tattattgct ttcgtatata taatccaact
      481 cttcttctaa ggtttctggt ggtaacagga gttctgcttc atccaaaact aaaaattctg
      541 tctccttatt aacttgtccc atcatcaaaa gaatgtcttt tgcatctcct ggcactgctt
      601 cccgcaagat gatcccaact tcttcactca tgattttcag cccatttttc tagaattcgc
      661 tgtttgaagg tttcactttg ctccccgtat gagattagtt tcacataccg cttttctaaa
      721 tctgtatcac ttttttctaa aatcagttcc aaataatcct ccggcagtgc ttcttctaat
      781 agatttcccc attcaacaac ggaaagccca tcaccttcaa aatattcatc taaccctaaa
      841 tctgctccgc tagctgctac ccgataaata tccatatgat acaacggaat ccgaccttga
      901 ctatattctc taataatcgt gtatgtcgga cttttgatca tttgcgttat ccctaatcct
      961 tgggcaattc ctttcgtcaa cgttgtttta cccgcaccta gatcaccagt caatatcaga
     1021 ttgtcacctg gcattgcgga atgaccaatt gcctctgcga attgttctgt cattgttaat
     1081 cctgatagtt cgatcatttt tcatcttctc ccgctcttct ttctttttgc cagtatatcg
     1141 cgtaatgaag tttttttaaa gaaaaaatga actagtcaag aacagcagct gctgtttttg
     1201 gctagttcgc gtgtatttgt taatcaatca atgtttgtgc tgctgtgata atcgataatt
     1261 tatatacatc ttcttcattt gctccacgag acaaatcaga aaccggtttg ttcaagcctt
     1321 gtagaattgg tccgattgct tcaaagttac cgaaacgctg agcaatttta tagccgatat
     1381 ttcctgactg caattctgga aatacaaaga ctgttgcttg accagctact tctgaatctg
     1441 gcgctttcag ttgtgcaact gaaggaacat aagaagcatc aaattgcaat tcgccgtcga
     1501 tcatgtattg tggcgctagt tttttagcga ttttagttgc ttcaactact ttgtctactt
     1561 ctggcgattt cgctgagcct tttgtcgaga agctcatcat tgctactttt ggttcgatat
     1621 cgaacaattc tgctgttttt gcagaatcta cggcgatttc agccaattct tgcgcagttg
     1681 gattcacgtt gatcgcacaa tccgaaaaga catatttttc ttgatctctt ccacgtacca
     1741 tgatcatcgc tccgcttgtc cgactgatgc caggctttgt tttgatgatc tgaagtgctg
     1801 ggcgaacagt gtcgccagtc gaatggatcg ctccagagac cattccgtct gcaatcccca
     1861 tatacgtaag catcgtacca aagtaattca catcttttaa aatcttttct gcttgttctt
     1921 tggatgcctt tccatttcta cgttcaacaa aagtatccac catttcatcc cacttatcgt
     1981 aattatcagg gctgatgatc gtaaagctag atgttttgat tcctctggca tgcgctgcat
     2041 ttcttatttc ttcttcgttc cctactaaaa tgggttccac aagttcttct gctttcaacc
     2101 gggcagctgc gcctaaaata cgagcatcag tagcttccgg gaaaacgatt ttgatcccac
     2161 ggcgaacaat tttaaatctt aaactatcaa acaattccac aagatgacct ccagacgttt
     2221 ttatatgtat tatcatacac tattccagaa aaaaagaaca gtttatttta tctgtatcag
     2281 tcaaaaatgc tggaaaaatt aagtttttca catacaaagc gaactgcact ataacaggaa
     2341 agcgctgttt tattacactg tttcaggcag ttgccaatca atcggttctt ctcctaacgc
     2401 aaggagcgca tcattcgttt tcgagaaggg tttggaacca aaaaagccac gacttgcaga
     2461 taacggactg ggatgtggag atgttatgat gatatggcga ctcttatcga tcattttgat
     2521 tttttcttgt gccggttttc cccacaagat aaacacgatt ggtttttccc gttcatttaa
     2581 tttttcaatg atcgtgtctg ttaatctttc ccaacctttc ccgcgatgag aatacgcttg
     2641 cccttcccga acggtaagaa cggtgttgag taaaaggact ccctgtttag cccatgacac
     2701 tagatttcca tgttgaacag gtgcgattcc aagatcatca taaagctctt tatagatatt
     2761 tcttaacgat ggcgggatct ttacgccagg ttgcacagaa aaagataagc catgagcttg
     2821 attttctcca tgataaggat cttgtcctaa aatcaccact ttaacttctt cataaggagt
     2881 caattccaat gcttcataga tatgatacat atctggatgg atcttttggg acgcatattc
     2941 tttttttaaa aattctctta gatgcagata ataatctttt gaaaattctg aggacaaaac
     3001 ttcttgccaa ctgttatgaa tgatttcttt caaaaactcc acctcctaat aaaaagaata
     3061 actcacattt tcttcaatca caagggacaa tcttcaccct cagcacttga ttaatatggt
     3121 aaactaggaa caagaagcag aaaggaacga taatcattat gatcaaatta attgcatcag
     3181 atatggacgg cacattatta gatgcccata tgagtgtttc tcctgaaaat gccgaggcga
     3241 tacgttttgc aaatgatgcc ggtgttgagt tcatggtcgc tactggtcga aactatcaag
     3301 aagctcgcgc agctttagat gaggtaggaa tcgattgtgc gatgatcact ttgaacgggg
     3361 cacaggtatt tgataaagaa ggaaattcat tgtttaccgt gtcgattcca aataatcaag
     3421 caatctctgt tttagatatt ctagatgcta acggtattta ctatgaagta gcaaccaacg
     3481 atggtcttta ttctgaaaat caagcgaaac gaattgaaag ttttgcttcc atggtggcta
     3541 cccatttacc tcaccttacg tataaaatgg cgattgccat ggcctcagct aagctggagt
     3601 tattgcacat cacatacgtg gacagtattc gtgctatttt ggaagaaaag aatctggaag
     3661 ttttaaaaat tatttgtttt catacagaag ggccagctgt attaggtcca gttggaaagc
     3721 agatttctct tttaggcgat ctagccgtta cttcctctgg tcaaaacaat atcgaagtga
     3781 accataaaaa cgctcaaaaa ggaattgctg ttgcccatgt cgctcacgag cgtgggattt
     3841 ctttagaaga agtcatgacg attggcgata acttcaatga tgtcagcatg ctgcaagtag
     3901 caggagtcag tttcgcaatg ggaaatgcag aaatcgaagt aaaagattat gccaaatata
     3961 caacggacac aaaccttgaa tctggcgtag gaaaagccat attgcgcgcg attgcagaag
     4021 acttgtagtt ttatctagaa aagagggata tagatgtcag aatttttcat tcaggaaaag
     4081 cagcttggac gtgcaactcg gacaattgtc aaaaacgaaa aaggacattc cctgtttttg
     4141 atggttggtc gctggggaac aaagggcgat gcattgtctc tttatgccat gaatggcgat
     4201 ctcgttgctc acatcaagca gataagcctg acattcggta cgcgttttga gctgtataaa
     4261 gagttcgaaa aggtgggaac catgcagaaa atattcaatt ggcccggtga cttttattat
     4321 attcgtagac ttcactggac agtccaaggt gatatctata atcatcaata tcaaatccat
     4381 catttcaatc agcaaatcat gaaaatggat aaagcaacac ttttttcagg agattactat
     4441 gtattggatg tctcaaatga tgaagatgct ccagtttgta tttgtattgc tgcggtttta
     4501 gattactggc tctaccgtaa agacaaaagt cgcgataagc ctgtttctta ccgacttaac
     4561 ttaagttaaa aagatgtacc tgaaatgcgg aaatacgcat ttcaggtaca tctttttaga
     4621 tattcttttg catatgatca taaagatgac cactgatcat ccgctgaccg acaactttga
     4681 agtcatggcg ttcgtataat tttttagcct ttggattttt ttcatccaca cttagaccga
     4741 tgacggagcg attagctttc ttcgccaatt taggtaatgc ttctaataat cgcgaaccga
     4801 tgccttgtcc tctaaaatct tctgatacac tgatagagtc caaataccat tcgttgggaa
     4861 acgtttcttt atcaatgaac aaacgtgtag acgcatctag ctgatatttc tctaagatag
     4921 gtaccagtgg ctgatcgatg attgattctt cttcatctgt ataaccgtaa gcaactcctg
     4981 caactttacc gtctatttct tctacgatac ctcgtgaata actgtaacga taatttggat
     5041 cagtgattgc ttcttctaaa atctctaaag tcttttgttc ccctgtctgc ttcaaaaatg
     5101 gcagttccat atcttttaga atcactaaga tcaatggggc gatttctgga gcatcttctt
     5161 ttctcgcaaa acgaatcata gtttcctctc cttttctcca ttctaacatg cagaaaaaga
     5221 aatcgcaaaa tcgttatttt aaaaaatctt caatcttttc agtaatgaaa taaccatgag
     5281 taacgattct tgccgcttca gttcggcaat aagggcagac gactggcatt tctttatcat
     5341 tatgttcgac tacattattg acttcttcgt atgcaaattt ttttccgcaa ttagggcatt
     5401 tcattttttc catgttatct caacttcctt tcatctttac tctcttagct tactcttata
     5461 ttgtaaaaaa gagaagcaat atccttcttc tatgcagata tccatacctg acggtcctgt
     5521 tctccatcta ttaatcggac tttataataa ggacgttcat ctttgactag aagtgtccac
     5581 tctttcactt ttgctttttt cccgtagtag ctgactgctt ccttcatcgc tgcttgcggt
     5641 tgtttgaact cttccgtttt ttctatatca aaaagatgtt ctgcggcctt ttccgtgtca
     5701 tttcgtacgg ttgttttccc agtggatgga ttgactgcta tgacttgtcc ttcacaaaaa
     5761 aactggtatt catatgttgc attcgtagga ttctccaaat ctttttcaac tgcaaaatga
     5821 atagcagata tgttatgttc ttttgtttcg ttttttacga ttgctgctgc ttttttcaat
     5881 gagatccgat attcctggtc actaatatca tccatgtgaa aagcggcatt gagcagtccc
     5941 gtcataccgg taatccctat tacgatgagg gcagcaacac caaacatcat ttttttcatt
     6001 cttcattctc ctgtttcttt tttttaaaga atatcaagaa atgaacgaat gaaaaatcga
     6061 atgaaacgaa aaaaaagtga caattttgtt atctttattc gtgcagttct aatggcaatc
     6121 cgtctggatc aaagaaaaac gtcatttttt ttcctgtaaa ggtatcttct ctaatcggtt
     6181 ctgattcgat ccctaaggac tgcaattctg caattgtttc ttcaatatcg tctactttga
     6241 aagcaagatg acgcaagcca caagcttctg gatagtttgg tcgttgtggc gcattagcaa
     6301 ttccaaaaat ctccaattca gcacttccta gtttcagatc taatttatag tcatctcgtt
     6361 ctttgcggta attttctctg attacttcaa atcctaattt attaacataa aaatcacgtg
     6421 atttctgata atctgaaaca atgatggcta tatgatggat cgttgtaagg ttcatatgag
     6481 cactcctatt cttcgtttaa gctcggatct atattaatct ccagttccat tgtaaatgtg
     6541 tcagattgaa aaaaatagct gtttttcctt tttataagaa aaaaggcaaa aaaaacagaa
     6601 agtaggtcct ccaagacact cttcctgttc ccaatataat aaatgaaagt aagaaattat
     6661 attttcaaga aaacaaacag aaaattatca taacacaaat tatttataat tgaaagacta
     6721 gttttttttc aagaaaagca tacaatagat tgtgttagta aatacagaac acactacatt
     6781 tagtgtctta aggagtcctc atacatgaag tcatattttc agtttttagc tcatcagcta
     6841 aaaggctggc cgcaacaaaa ttattatctt ttctttttca gtcttggctg ccaggtcatg
     6901 actcttgtca atagtcccat cacttggctg tccgttatta catttatcgg taccacgctt
     6961 ggtgtattgt gtattttatc catcaatgcg gcaaaatcag tcaacggtat tttaggtatt
     7021 ttgtctgcga tttgttttat tatcgttggg ttttcagcaa agaactattt aagtatcggt
     7081 gaacagattg cttatatgat cacattggat atccccgtat tgttaagtaa agaatggaat
     7141 cataatatgg cttcaaaaat ccgaaaattc actggaaaaa gctggtttat cgcaatcatc
     7201 agtactttcc ttgtctatct tgtttcagga ttcctgattg gtcgttatac agatgatcct
     7261 cggccgtggg tagatgccat tgctttttct attagcttga ctgctggtat catcagtttc
     7321 ttgcgttaca acaaccaata ttactggtgg ttagcttcag ggcttgctca aatggtcctt
     7381 tggtatattt catttacgca tggatctgca agtttggcga tgttcgtgaa cagctctgtt
     7441 tacttgctga atgatgtcct tgcatttacc gtttcacctt ggtataacca aaaagaacgt
     7501 gaacgtatgc aaaaaatgga agaagaatac tacaacgcac aacaacacgc ataaaaaaac
     7561 tgagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc
     7621 ggaatcagaa gcaactcctt cggaaataag ctgaaattca caaaaatttg aaaagcaatt
     7681 ttcgtgaatt tcttcttatt tcttggagtt aaacgcttct gt
//
LOCUS       DBBGRF010000092         7599 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000092 DBBGRF010000000
VERSION     DBBGRF010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.093"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(137..427)
                     /locus_tag="ACIZD4_002767"
     CDS             complement(137..427)
                     /locus_tag="ACIZD4_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991621.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(545..805)
                     /locus_tag="ACIZD4_002768"
     CDS             complement(545..805)
                     /locus_tag="ACIZD4_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991622.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(942..1355)
                     /locus_tag="ACIZD4_002769"
     CDS             complement(942..1355)
                     /locus_tag="ACIZD4_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HGC5991623.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1811..2296)
                     /locus_tag="ACIZD4_002770"
     CDS             complement(1811..2296)
                     /locus_tag="ACIZD4_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991624.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2435..2650)
                     /locus_tag="ACIZD4_002771"
     CDS             complement(2435..2650)
                     /locus_tag="ACIZD4_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HGC5991625.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2874..3674
                     /locus_tag="ACIZD4_002772"
     CDS             2874..3674
                     /locus_tag="ACIZD4_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGC5991626.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3693..5561
                     /locus_tag="ACIZD4_002773"
     CDS             3693..5561
                     /locus_tag="ACIZD4_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGC5991627.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5554..6045
                     /locus_tag="ACIZD4_002774"
     CDS             5554..6045
                     /locus_tag="ACIZD4_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HGC5991628.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6033..6587
                     /locus_tag="ACIZD4_002775"
     CDS             6033..6587
                     /locus_tag="ACIZD4_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HGC5991629.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6605..>7599
                     /locus_tag="ACIZD4_002776"
     CDS             6605..>7599
                     /locus_tag="ACIZD4_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HGC5991630.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2236 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagctttgtg aatatttcat ctaatacgat acaaaggcta tctttctaat ttgaaaaagg
     1501 gatcattaaa ataataagaa gaaaatatgt caaaaggtaa aaaagtaaat tcttctatcc
     1561 aaatatagaa aaattgaatc tagaaaaccg cccgacaata aatttcatta actcagttga
     1621 ccgaaaatga agtagatacc aaaaatttat caagagagca agtagagaag tgagtatatt
     1681 cataagagaa atagctgtaa cgaattatta ggttaatgca aatgcttatt tatactccgt
     1741 ataactttct cagaaaaaat gataccaata atgacttgct agtactgtaa atccgtataa
     1801 tatcatctaa tcaaaatggt gttccatttg catctgtcat cgtaatcgat ccttcgggtg
     1861 acactcgata aaaaccaacg cttccagatc ctccttggga acggatttgt ttgctggaag
     1921 ctgtgaacaa ataatctcga tcaatttttt gataaaagct aataacaata tcgtcacttt
     1981 gtaattcgga acggtgggca ataagaaata gaagtgcttt gtcagagttt tctaatggaa
     2041 gagaaggtac agtgctttct tgcatttcag atgttgaaga aatgctaaac gactgaatac
     2101 ttgattggct atgttgcgaa tctacattac cagtagaagt attagtaatg gaagtagtag
     2161 aagtactttt agttgaacca acctcagttg ttgaaatggc tgctgaagat tctttaacag
     2221 aattctttgt tttatatcca caggcagaaa aaagtattac agttcccaac aagcctgcgt
     2281 aaatcccttt atgcatgata gctcctccta aaatagatta tctttattca gtatatcact
     2341 taaacaaaga aaagcagatg gtttaaaatg aaaaaacctt cccaataaag ggaaggttca
     2401 tgaagataat aactttttta ataattatag ctttctaata tctttcatca acttttctag
     2461 taatcattgg gaaaaatttc aagcagtaga tcgcacaaat acctacgacg atataaatga
     2521 tcttcgcaaa aatagttgtt gaaccaccag caatcatagc tactaaatca agttcgaaca
     2581 agcctaccaa cagccagttc aaccctccca caatcaataa agttaatgca atagcatcta
     2641 aagttttcat tagaattctc ctttcttaaa tgataaaaca attatatatc aaaaagagaa
     2701 acattgctta tataacgctc aggaatttta gcaatctatg caaaaagatg aaaatttttt
     2761 ttgctcttcc attagtacac attttttagc tgaagctgta aatttcatgt cttaattttt
     2821 tttagtgagc ttttatactg gatttgtaag aaaaaagaag gagaggatca catatgtcgg
     2881 attggttgga tattgcagga aaagtagtaa ttgtaactgg aggttcctca ggaattggaa
     2941 gaagtatcgt cgaaaatttg ttgaagcaga atgcacaagt agcgaatttt gatgtaactg
     3001 aatgccgtat acagcatgaa aacctactat ctttaaaagt cgatgtgtct tctaaaacgg
     3061 acatagaaga agggatatat aaagtaatga aacatttcaa gacgatcgat ggtctagtca
     3121 ataatgcagg aataaatatt ccttctcttc taatagatag aaatcatcca aaaagcaagt
     3181 atgaattatc agaacaagtt tttgataaga tgatcgctgt caatcaaaaa agtgtatatt
     3241 tgatgagcca agcagttgga agaatcttgg tgcaaaaggg atcaggagtg atcgtgaatc
     3301 tttcttctga atcaggattg gaaggatcag aaggacagag ctgttatgct gctacaaaag
     3361 cagcgatgaa cagttttact cgttcttggg caaaagagtt aggaaagagg aatgttcgtg
     3421 tggtaggtgt tgcaccaggg atactggaag aaaccggttt gagaacacaa gaatatgaag
     3481 aagctctttc ttatacgaga ggtataagcg tcgaacagct gagaaacggt tacagtcgaa
     3541 caagtacgat ccctctagga aggagtggta agctgcaaga agtggcggat ctagtctgct
     3601 attatctttc agaaagatca agttatatca ctggagtcac gactaatatt tcaggaggta
     3661 aaacaagagg ataaaggata ggggggacgc acgtgacgct agtaaacaga tggtaccaat
     3721 tattgaaatt actagtcact cacaagaaag tttcaatcca ggaagtgcaa aaagaaatca
     3781 aaaccagtaa tcaaaccata aaaaaagata ttggggagtt gaatgaagaa attgccggta
     3841 ttgcaaaaat catccaaaaa aacaaacatt ttgaacttga aatttatgat tttgattttt
     3901 ttgatgagat catgcaagga aaattgaaaa cagccagtga tttcaattcg gcatccaaaa
     3961 gaatcgctta tttactaaat aggctgatcg aaacagagga tttcttacgt atggatgatt
     4021 tgtctgaaga agtcggtgtc agcagaggaa cagtggtcaa ggatctaaag acattaaaag
     4081 agatgatcaa tgattttgat gtaaagatta caggcacacc aaataaagga ctaagaataa
     4141 taggagatga gctagaatta cgactacttt tattttattt tgtttctccc tacttttcag
     4201 agacgaaaac agaacagttt ctagaagaaa aacaagcaat caaacatttt cagaagaaga
     4261 cgaatgctag taaacaagaa atcacccttt taacgaaagt tatcggtatt tctttgaata
     4321 gaatctctag taactatctg ttgaagaagc ccatcaatcg ttacagtggg tgttttgaat
     4381 atatccaaga attcaatgaa ctgatcaatc agttggaaga aatctatgaa ctaactttga
     4441 gccaatatga aaaagatttt atcagttttc ctttgaacat catcaacaca agtataacga
     4501 tgataaggaa agctaactct gatttgcgct tatatttcga ccccatgatg atgcgtattc
     4561 gacgattaga tctcattgat ctggatgagt ccttcttata tcaagagatg aaacagcacc
     4621 tctctttatt gataaatcgg gtaatttttc gttatcgatt gactgattta ttttatggtg
     4681 agatagaaaa aaagtatcct ttttcttacc aaatcgctag cgaatgcata caagcattag
     4741 aagctatctt gcaacataag atctctaaag tagagatcag ctacctaacg ttgtatttgg
     4801 agttagcatt tcgatatcaa aaagagcatt tttcctctaa aaaagtagcc attgttcata
     4861 cgacaggaaa aggaacagca ttaatgatcc aaagacaaat caaaaggata ttggggaggg
     4921 atatacaaat aacacatgtt tcagaagaac aatatgaaaa agtagatcta aacaaatatt
     4981 tcgctgtttt tacaacgatt ccgttaaaaa atgtaaatga agagacaccg gtgatccatt
     5041 tgactaatct ttttgatgac tcttggttaa gggcacaatg gcaaaaagca aaaaaaaagc
     5101 gattagccgg gtttcattct actgtttttt tctatcaaat atggaaagaa aaaaagacgt
     5161 atcaagaata tttaaacaaa ttagtcgctc ctttgatcag aggctattat gtggatgaag
     5221 aatttgaaaa aaggatcttg aaaagagaat atcagcaaag cacatttgtt aacaaagaat
     5281 ttgcttttcc tcacacaacc aaccagctat ctcaacacat tgttttatca gtagggctaa
     5341 taactgatca aggtttagca gaaacaggag gaaatggagt tattttttta tttgccatac
     5401 ctgaagaaat gacggctgaa gttgagaatg aattatttga gctatacgat atcctatttg
     5461 aactcataaa aatgggaata gatgagttta ttgaattagc accgacacaa gaatcatttt
     5521 taaaactaat caaaagtaaa ggagagagac ttcatgaatg atatgtatct attcatagtt
     5581 ttcgcagctt cagcttatgt gctgcaagca gttatcagtt ggaagcaact aaagcatttc
     5641 aatcaaacat atagcgaact gcgaagaaaa ggaaaagtag cgattggtaa acgacctggg
     5701 aaaatccgtt caggcacgat tgttatgcta gctatagacg atcatgatca agttttagaa
     5761 gtcagaaaaa tgcaaggggt tacatctttg gcaaaatttc attcattacc tgtctatgcg
     5821 ggtgaagata tccattacat cgatcgttac catccctcag ttcgagcgga agatcgtttg
     5881 acacaagcag ctttagaaaa tgccagagaa gtatacttac gaatagaggc aggaaatgaa
     5941 aaaagtgaac aaccttcatt gccttttatt gctatgctca ataattttcg gatatggaaa
     6001 agtacgatca aagaaaaaag gagtgacaaa cgatggatat cataacaaaa tttgctgagg
     6061 gatttatgag gctgttccaa acaggtgcag aaacattcat aagctggatg acaggaatcg
     6121 taccagttgt cttgatgctg atggttgcaa tgaatacgct gattgctttt ttaggtgaag
     6181 accgagtaac gaaagtagcc aaattatcag cgaaaaatcc gcttactcgt taccttgtgt
     6241 taccgttctt atctgctttt atgttgggaa atcctatgtc atttacaatg gctcgtttcc
     6301 ttccagaata ctacaaacca agctattatg ctgctcaagc tcaattttgt catacgagca
     6361 atggtgtatt cccccatatt aatcctggag aattgtttgt atggatgggg attgctcaag
     6421 ggatcgaaac cttagggcta aattcgatgg agctggctat ccgatacttg cttgtgggac
     6481 tgctgatgaa ctttattggt ggttggataa ctgattttac tactggattt gtatgcagac
     6541 agcaaggaat cgttcttagc aaaaaagtag agctttcagt tgattagaga aaggagagtt
     6601 ttaaatgtat ggtgatatta agatcgtaag aggaaacggc gggtatggag gtcctttgat
     6661 tattaggccg acaaaagata aacacaagtt catctatgtc acaggtggag gtgagaggcc
     6721 aatgatcgta gataaaatag aagaactgac aggtatggag tctatcaatg ggttcaaaac
     6781 atcaatacct gatagtgaaa tcgcgcttgc aatcgttgac tgtggaggga ctcttagatg
     6841 tggaatttat cctaaaaaag ggataccaac catcaatatc gtttccacag gaaaaagtgg
     6901 cccattagca caatatatca ctgaagatat ttatgtttca gcagtagggt tagaacaaat
     6961 acagccacta atggaaactg atgataacaa agaaacagta aatactgcat ctccagataa
     7021 aaagtacaaa tatgatactt ctaaaaagat aaccgagcaa aaagcagagc agcaaaactg
     7081 gatagcaaaa attggaatgg gcgcgggaaa agtagttgct acattcaatc aatcagcaag
     7141 agaagcagta gatacgatga tccggacagt gatccctttt atggctttcg tttccctttt
     7201 gattggtgtg atacaaggtt ctgggatcgg taatgtattt gctaacatta tggcaccttt
     7261 agcaggaaat gcagttggat taacaatcat tggctttatt tgttcactgc catttttatc
     7321 tcctttgctt ggtccagggg cagttattag ccaagtgatt ggaacattga tcggtgtaga
     7381 gattgggaaa ggaaatattc ctccccaatt agcattaccg gcactatttg ctatcaatac
     7441 tcaaaatgca tgtgatttta ttccagtcgg tctaggtttg gaagaagcaa aagctgagac
     7501 agtagaagta ggtgtaccat cagttcttta ttcaagattt cttaacggca tcccacgagt
     7561 tatcattgct tgggtagcaa gttttggatt atatagctg
//
LOCUS       DBBGRF010000093         7537 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000093 DBBGRF010000000
VERSION     DBBGRF010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.094"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            107..1248
                     /locus_tag="ACIZD4_002777"
     CDS             join(107..335,335..1248)
                     /locus_tag="ACIZD4_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC5991631.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1483..1935
                     /locus_tag="ACIZD4_002778"
     CDS             1483..1935
                     /locus_tag="ACIZD4_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991632.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1949..2638
                     /locus_tag="ACIZD4_002779"
     CDS             1949..2638
                     /locus_tag="ACIZD4_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991633.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2763..5114
                     /locus_tag="ACIZD4_002780"
     CDS             2763..5114
                     /locus_tag="ACIZD4_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HGC5991634.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            5194..5589
                     /locus_tag="ACIZD4_002781"
     CDS             5194..5589
                     /locus_tag="ACIZD4_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991635.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            5914..6531
                     /locus_tag="ACIZD4_002782"
     CDS             5914..6531
                     /locus_tag="ACIZD4_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5991636.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            6572..6871
                     /locus_tag="ACIZD4_002783"
     CDS             6572..6871
                     /locus_tag="ACIZD4_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HGC5991637.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            6905..7072
                     /locus_tag="ACIZD4_002784"
     CDS             6905..7072
                     /locus_tag="ACIZD4_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGC5991638.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(7117..>7537)
                     /locus_tag="ACIZD4_002785"
     CDS             complement(7117..>7537)
                     /locus_tag="ACIZD4_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5991639.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2594 a         1138 c         1502 g         2303 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc gtagaatcta actactaaga aaaggacgtg tccacgatgg caaaagccaa
      121 gaaaaaattt gatgaagact ttaagaagat gatcttagat ttaaaccagt ctggccaatc
      181 ggtcgaagaa ctggcagcgc aatatggtat cgctacacaa acgatttatc gttggaagaa
      241 gcttcataca aagaatgtag caaccggcat gactgaggca gaaatcctag cgatgaaaaa
      301 ggaaatggcc cgcatgcagg aggaaaacac tatcctaaaa aaggctttaa ccatattcgc
      361 tcaaaagtaa aaatgagtga tgtcttcgaa tttattcaat caaatgttca tgatcatgac
      421 gtaaaacaaa tgtgtaccgt tttggaagca ccgaaatcca gctactatga ctggaagaaa
      481 aagaaacctt ccaagcgcca atcagaaaac aaacgcttaa accgcttgat ttcaggaatc
      541 tactttgaaa acaagggtat ctatggtgcg cctaaaattc ataagattct tgttggccgt
      601 ggcgagacct tgtccttaaa gaaagtacaa atactgatga gaaaattagg cttgcgttca
      661 gtcaccctca agaagtacaa gcctggcaaa caagcgaaag ttaaaagtga aggacgtaaa
      721 aacctgttaa accaagattt taccactacg tcgatcaatc aaaaatgggt gacagatatt
      781 acctatattc ataccctaaa agatggctgg acctacctct ccactattca agacctccac
      841 acaaagaaag tcatcggttg gaagtttggc aagcagatga cgaaagaatt ggttatcgaa
      901 acccttgaca atgcgctctt aaaccaaaca ccctccgaga acttgatcat ccactcagat
      961 ttgggttctc agtacactag cgaagcctat gaggcaaagc tgaatgaatt gaacattcgg
     1021 cactccttca gtcgtaaggg ctgtccctac gataatgccg gtatcgaatc gtttcacgcc
     1081 tcactcaaaa aagaagaagt ctatccatca aaagcgtatg aaaactttga agctgcttat
     1141 ttagcgttat ttcaatacat tgaaggattt tacaatcgca agcgaatcca tagtagtatc
     1201 aactatttaa caccaaatca gatggaggag ttggcattgc aagcttagtt cctagctacc
     1261 acttacattt ttttggcgag atttccacag ggtttcaact tcatcgcttc gatcagcggt
     1321 caaacggttt tggtttgacc gctggtcgaa acgatgagat actcacccgc tggaatctcg
     1381 aaaaaattct cacaaatcgt gtccgaggta ttgactcaaa tccaccaatt atcttatcgt
     1441 agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa aacgatacta
     1501 agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa tttagattct
     1561 gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa taaaaaaatg
     1621 agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga atttggtgat
     1681 ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga taaaattgtt
     1741 gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt tagttataaa
     1801 caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc gattaaggat
     1861 ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga aactaattca
     1921 gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt ctgttgggct
     1981 acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag ttatttcaga
     2041 tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata aagtacttgc
     2101 attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg ataatccaga
     2161 tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag tgacagaagc
     2221 aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa ttatgcctcg
     2281 aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag caggaggagg
     2341 aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta tgggtgtaaa
     2401 accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg atggaagagt
     2461 aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa tggcattgta
     2521 tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa tgaatatagg
     2581 tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa atatttaata
     2641 aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg acaaacacta
     2701 aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag caggggattt
     2761 ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac agtaatgtta
     2821 cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc tatggactta
     2881 ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt ggacctacca
     2941 ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta cctaaaaata
     3001 ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt ggcttcgatg
     3061 gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat gcagggttta
     3121 atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta tttgatatga
     3181 gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag caatggttaa
     3241 atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat caaagaaatt
     3301 caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc agtgaagcaa
     3361 cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa ggtaactcgg
     3421 gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt gaagacggta
     3481 cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc cgaaaattta
     3541 tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga ctattgtcta
     3601 gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa ttaactagat
     3661 ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat cttactggta
     3721 ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa ttgaataata
     3781 ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca gcattagctt
     3841 attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca gcaaaaaatc
     3901 taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg ttaggggaag
     3961 aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg tcatatagcg
     4021 ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc aataacgggt
     4081 atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat ttaggttttc
     4141 ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga agtggcaacg
     4201 gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt aatgagttat
     4261 caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt ataaatcaga
     4321 tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg aaccctcatt
     4381 tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt tcttctcctg
     4441 taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact aatagcgagg
     4501 gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg cctcacttaa
     4561 ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt gtttctgact
     4621 ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa ttaggaatac
     4681 aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca tttagtctag
     4741 aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa agaaattctg
     4801 attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct attgatagat
     4861 ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca gtaacaaata
     4921 gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt tcatttttca
     4981 ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat tttattggag
     5041 atgaggggaa agttgcaaat ggattttctg aaaaaattat tcaatttcaa gaaaatagaa
     5101 gtaaacttaa ttaagaatcg tttactattt aaacagtgtc cttttccttt ttaaatatat
     5161 acgataaaat aagtatatga attgtaaaag gacatgatga ttatggaaga aatagaatgg
     5221 aataatctga ctcaaaataa taaaaataat tctggatgtg gaattatctt tatgtttgtt
     5281 atagttttgg gaatagtagt acttttaata actgtcaaga tagtagatta ctttgcgaat
     5341 actcctgaag aacaaataca gagaaaactt cctgagtttg aaagagtacc accttatgat
     5401 ccaagagata attcatttca agtaaaaaaa ttaaaagagt ctccaaatga aatgtggttt
     5461 gaagttacag ttgaatcaag cgacttcaaa gaaaaaaaga aagaatacaa ttatattgta
     5521 aaggcaaaag tatcaaaaag atttattttt aaccctaaat tagaaatata tagtgttgta
     5581 atagaataat agtgttaaaa aaattgtaaa agttaaagaa gtcaaattct gatgtgaaaa
     5641 ataaaatata ccatggaaga cataaaagaa aaactggata actagtttat ttaatggcag
     5701 accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca tgcgggagtg
     5761 taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt tgtttatgta
     5821 tggcataata accacataat acaatttgaa acgtttctga tttaatctga ttgttttgaa
     5881 acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta tatccgggtc
     5941 agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt aggaatccct
     6001 gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc tgaatatcaa
     6061 ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt agatagacta
     6121 ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga aaagcagatt
     6181 gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca actagatggg
     6241 ttagagacgc ttatctctga cttaattctg caattactca gctatatggc cgaagacgag
     6301 cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca aaagggtgta
     6361 aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta ttctgactgg
     6421 aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa acgaaatacc
     6481 ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg atagatataa
     6541 cagctattag acgggaaggg agagtttgaa aatggactta acgaatcaaa gggtcgtttt
     6601 tactggaacg ctgcagcaaa tgacacgaac ccaagccatc ggtttggttc actctttaaa
     6661 cggccattgt caatcaagtg ttacttcaaa aacaaatttc ctggtttgtg gtcagtattc
     6721 taagtcgttg tttgatgatt ctctctatac aaaaaaggaa caaaccgcgc gggacttgat
     6781 tgcgttaggt catgagatta ccattttatc agaagtcgaa ttttatgcgt taattagtca
     6841 acagttgaaa gaatggcaac ggtatttata atcgttagta aaatttacaa ggaggaaaat
     6901 ttttatgaag cgaaaatctt atgatcgttg gggcattgaa ataactagtt ttaatcgaaa
     6961 tattgctttt cacgtggagt gtgactgtgg ggaattagca aaaagtgttt atcaaaaaaa
     7021 ttacttttac tgtcctaaat gccatcgccg atacggggta catggaacat agaaacgaaa
     7081 tagtgcggta gaaaagcgaa tgaatgtagt atatttctac aaatcattcg ctttctttat
     7141 tttataaata gttggtcgag agatcccgtt ttcttttgca atctctgcaa ctggaatgcc
     7201 ttgctttaac atgtccacca cggttttaaa aactaagcgt ttttgcggat ctgttgagtt
     7261 aatagaatac tcgattggtc gtcccttata tcggccggct ttttgagcca ataatactcc
     7321 ttgccgctga cgttcacgaa ttttctcacg ctcgttttgt gcaatataac ttagcagtga
     7381 taaaaacata tcgaacatag cggtatccag gagttcattt ccagtattaa aatctaaaaa
     7441 ctgtgcatct aatattttta acgctacttt tttctgtttc ataaaagcaa ctgtattttt
     7501 tatatcttca taatctcttc ctaaacgatc tagtgat
//
LOCUS       DBBGRF010000094         7474 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000094 DBBGRF010000000
VERSION     DBBGRF010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.095"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            275..1753
                     /locus_tag="ACIZD4_002786"
     CDS             275..1753
                     /locus_tag="ACIZD4_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991640.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            2030..4090
                     /locus_tag="ACIZD4_002787"
     CDS             2030..4090
                     /locus_tag="ACIZD4_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGC5991641.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            4173..4742
                     /locus_tag="ACIZD4_002788"
     CDS             4173..4742
                     /locus_tag="ACIZD4_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991642.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4917..5723)
                     /locus_tag="ACIZD4_002789"
     CDS             complement(4917..5723)
                     /locus_tag="ACIZD4_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991643.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5861..7375
                     /locus_tag="ACIZD4_002790"
     CDS             5861..7375
                     /locus_tag="ACIZD4_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HGC5991644.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
BASE COUNT         2683 a         1226 c         1459 g         2106 t
ORIGIN      
        1 taaaagagca ggacggtggc cgtcctgctc ttttttgtgg ttgtttacgc aaatggcgca
       61 aatcttgtac attttaacac aataaaacaa aaaatataga atatttcctc ataaattttt
      121 ccattttttg caatattctc aaaaaaaaga taaaaaatga gaataactga tgaaaaaaca
      181 agcataatcc atcataaaat cagtataggt gaaaagatga actttcatct gcatatcaag
      241 taattggtat gaggcatttt ttgaggtgta ggatatgaag ttggattacc ttatagaaga
      301 ggaagataga gaaaaactgc tgctagctag atatttagaa tttgagaaaa agaattatgt
      361 agtgctgcct aagttatatg aaacattagg tttgtctaaa tttaaaacaa gaaattatat
      421 catagaatta aataaagaat ttactgaatt caaaacaaag ccagagatcc aaatttcaga
      481 agaagcagag atccatgtcg aacgtctgaa tttgacggat atcaaaaatt taagaagaat
      541 ctactttcaa cgatcaaaaa ttgctcgact gttaacggag atcgtggatt caaaagtaac
      601 gatcgaaaaa tttgcagaga atcatttttt aagcatatca agagcctatg taaaaagaag
      661 agaattagtc tcttttcttg aacagcatca aataaagtta aagaaaaaca tattagttgg
      721 ggaagaaata aacatacgga acgtattatt tggggtatat ttcggggtct ttaatggttt
      781 ttctatgcca tttagagaaa gcgtcatgaa tgaagcaaag agtatcgtgc aatattttga
      841 atatctgttc aatttaaaac tgtctgcaac aaaacgaatc aaattcaatt tgctaaccac
      901 tattagtttg ttgagggcct atgggaatca accaatcgga aaacgtttct tttcagatga
      961 atactttaag agctcagaag gaatgaagat catcaaggat ttatcacata tttcttttct
     1021 tcatatccct aaagagcaga tcattgatga gatttcttat atcatgttgt ttttgatcac
     1081 ggaagaagaa tttgaattag atggcgcatt tggacttgcg gaagctcatt ttcatgatat
     1141 ccacatgatt agtcaaaaaa tgtcagtgga attgattgat caattaccat tttcgattga
     1201 aatctctgaa gaagaaagac tatatatacg aaaagaactt cgtatgggta tgatgcatgt
     1261 caatcgaaaa aattggatat tcgactttga gatgactagc tttacgtcta aaaagcagct
     1321 acagtttttc ttcgagacgt atccaatatt cagtacagca atccaaaagg tcatacaaga
     1381 gaataaacgc tatttcttgg gaaaagatga acgtttcatg attcgcttat tttatgatta
     1441 tctcttttta ttggtcggta tttgtccggt atcatatttt gaagcaccga ttcatgtctg
     1501 tattgatttt tcgcaaggat ctgcttatac cgattacatt atttctcaag tgaaaggatt
     1561 taaaaattac aatattgtga ttgagagtcg aatcacttct cgtacgaata tttatttatc
     1621 tgattgttta cttgaaaaat ttaataaaga acagataatt tggaaaaatc caccgactcc
     1681 agatgactgg gaatattttg gaaataccat catcagagaa aaaaatagac atttaactga
     1741 aaaaatcagc tagtatttat ggatggcagc tttgtctcac atatttatta gctgatttat
     1801 gtttttttca aagaaaaggt aactagatat aactagatat aactagatat attacttaac
     1861 aaaattaaaa agtacataag ttattattcc gattttcttg aaacaataaa aaatcaaaaa
     1921 aaatactctc ctaatagtcc atcttctttt gattttattt atataatgaa atcatcttat
     1981 gaaaattact acttcatgtt tagacaagag tagggaggac taagaataaa tgtgttcaaa
     2041 aagacgttca aaacaactaa ataaacacgc ttgtcgttta gataaggaac ggtcgtgttc
     2101 tgaaaaacac tacgttaagt ttatgatgcg cacgatgctg atcagtttat ctgtaggtgt
     2161 ctatatgcat gtacccgttc aggcaacgac acaaaccatc aaggtcgtac gtacctctgt
     2221 ttctgagacc actgattccc ctatcactat tactcatact ttcactgatg caaatggaaa
     2281 acagctactt cctgcattga cttcctataa taaagtcagt tatcctccaa cgataaacca
     2341 ctactggtta attcctaaca aaacattatg gacatcggaa accggaagca gtgtgccgct
     2401 ttctatcttt tccgatatga ctgatcctac aaaaggtgat cagttaaaac agatcactga
     2461 tattttgaat catgctttga cagatataaa ggacggtgga agcgcacaag tttcttatgt
     2521 atatgaaaaa gattattcac agtttgaaag aaagaaaatc gatgttctgg cagggacaaa
     2581 agtttcgata tctgatctgg tagaaaggct gaagaacgca gatggaacac aaggagatat
     2641 gtccaaagta atttcaaaca atgggaatat cgtggatacg actaatacag gaacatctac
     2701 tatttccttg tcctattttg atccaattgc tttaaaaaca atgactgcat ctgctgtgat
     2761 ccatgttcgt gctgatcaaa cagctatcaa aggaaaagat cttcacttaa gaacaggaga
     2821 gagttacgcc cctaaagatc ttgttgaata tgtaacaaaa agcgatggaa cttcaggaaa
     2881 taaagaagaa atcaaaatga acgggacagt agatactaca actccgggag aatatcccgt
     2941 tgtattaact tatatagact cgaaaacatc aaatgtggca gaaacaacag ctgtagttta
     3001 tgtagaagca tctgctgctt catcgactgt catcactcat tttatagata gtcaaacaaa
     3061 taaagaactt caagcagaaa cacatatgag tagtgtaaat cgtattcctg atttgcgcct
     3121 acctgctgaa ttttctgatc gagtgccaaa tatagattta tcgacttatg aacaaaatgg
     3181 gaaagtcact tctatttctg attggatgca agcaaacgga ttagacagaa aaagtcactg
     3241 gtcggagatc cttgaagtac ttcactcaga actgatgaat aataggaagc aatcaggagg
     3301 ggaaattacc tttacttatg tttatatacc agacaatcgt tcattagaag gtcatgatct
     3361 tattgttcat ccaaacgaaa aaataaacaa agaagagttg atccaatcag caacaaattc
     3421 cttaggtaaa cccgtaccgt taaaggatgt atcggttaca atcaatgaag taccattgga
     3481 ggatggttat ttgaccaaac aaacaggtga ttttacgatt atgtatagtt atcatgaccc
     3541 gtattcactc caagaactcc atgctcagtc actattacat gttttaccat taaacaaaca
     3601 gatagatcaa aaagaacaaa aaagacaaga agaaagcttg tcagaaaaaa aacaacaaat
     3661 ggctcatgca gtttctccaa cagggaaagt aaaacaaaca agaagcctag agttagcaag
     3721 aatatctaga aaaatctcag aatctaataa aacgataagg caagaagctc atttggcccc
     3781 acaagtttct ggattggaaa atgaaatttt agagcctaaa ataaaacaac aatcagaaaa
     3841 agaatttgtt gctaaacagt cggaagatca gaaggaatca gatgaccaga aggaaacgaa
     3901 gaaaaaacgc ttgtcaacta ttgattccac cgatgagcat ctgcagccgc aagtaccact
     3961 tcctagtccg ggaacacccg cacctggtgg aggtattcct tcttctgctt taggagattt
     4021 catgcgaggt atggcaggaa catgggtata cgctaatcga aatgaatttg acgcagatga
     4081 ctggttctga tttatatctc tatctgttat agtcaaataa gtagctgagt catatgttat
     4141 ttggcataat ggagacgagg agggatagaa aaatgttaga taaaacgtta ccttacgcag
     4201 aaatctggat gacaagacca cttcaacaaa atgttccaat cacgccttta gcggaaggtt
     4261 ttgaatttcg attttatcaa aaagaagatg aatctgcttg ggcggagatt gagacttccg
     4321 ttggggaatt tcaaacgaca gatgaagcac ttgagtattt tcaacaaaac tttgctcctt
     4381 atcctgaaga acttgaaaga aggatgtttt ttgtagagac aaaaaaagga gaaaaagtag
     4441 caacctgtac cgcttggcga aaaaaatcaa gagagcaagt gtatccggtt tttcattggt
     4501 tagcagtgaa accagattac caaggaaaag ggctcgcaaa agcattgact gccagagtct
     4561 tgcaagaatt tcctaccctc catacggacg gaccaatcta tcttcacaca cagacatgga
     4621 gccatcaggc gattgctctt tataaaaaaa tgggttttac ttttattgct gaaaatctag
     4681 acggcacacc taatccagat tatgaaaaag ttatgcaggt tttaagtaaa ttagataaat
     4741 aacgaaatgg tgaaataagt cctcagtatt gggataaaaa acgaaatagt cattcctcat
     4801 atcttacttt tttgagttaa tactatcgga taactaatgg catgccatac attcaaaaaa
     4861 gaaggggcag tgacaaaagt attgtcactg ccccttctct tgttttttag catgttttat
     4921 cgtttgattt ttttaggaat aaaattcttg atgaacgtaa atttttggta atcgtttcga
     4981 ctatagaggt aaccaaatac actgaaaaca actgctccaa taaaattaac aaataaatcc
     5041 ttcatagtat ccatgattcc cacgtctaag taaccatttt ggatgattgt tttatctgtt
     5101 ttaccatctg cattttgact ttcaatgatt gtccgagtga tatctggaac atgatagaca
     5161 gtgtttccgt ctttacttaa ctccacacta ttgatttgct ggatgatcgt atctttttgc
     5221 atatcgaatt gcagtaattt atctgctgaa aattccacaa actcccacat aacaccaact
     5281 gtcatcgaaa aacagaagga aacaactgct agtaataaag gagtcaagtt catggttttt
     5341 gtatttttat tgagcaaata aacaagggaa aagccgacac ccccagctaa aaatccgctg
     5401 aatgcatgta gaaaagtatc ccacattgaa aaatagccat aaaaatcact taactctcct
     5461 aaaactgttg aactaaaaat aaaagataac aaaatgattt ctagcatatt tggaatctgt
     5521 atctttaata tcttttccag aaaataaggg atttcaaata aaattaatgt cagtaataaa
     5581 agcattgtat ttccccagtg ttggttccag acctgatcca ctagcataat aacgacgatg
     5641 atacgtaata aaatatagat tccgtttgtg attctacctg cagtttttgt actgttcgta
     5701 aaaaaggttt tcaaatgatt cataaaataa ctccttcatg tatatcctta attatactaa
     5761 gaagcgtgtg tttaccaaag ctatatgact taaagaaaaa cagagttgat attgtgaaaa
     5821 aaatcactta atatagtata aggagaaaag ggggatacaa atgaaaaaat tagttgctgg
     5881 tttattaaca gccgttgcac ttcttgctat gagcgcatgc ggcgcagatc agaaaaatac
     5941 agcgcagaca agttctagta cgaaggaatc tgccgaagta tcatcaggcg cttctgaaca
     6001 agtatataca gatccaaaag aaatgaaaga atcttatgat gtcgtgatta ttggagctgg
     6061 tggtgcaggg atggcagcag ctatcgaagc aaaagatgct gggttgaatc cagtaatttt
     6121 ggaaaagatg cctgttgccg gaggaaacac atctaaatca tcaagcggta tgaatgcttc
     6181 agaaacaaaa tttcaaaaag aagaaggaat caaagactcg aatgatgcct tctatgaaga
     6241 aacgctaaaa ggtggtggag gaacgaatga taaagaaatg cttcgatact ttgtcgatca
     6301 ctctgctgat gcggtcgatt ggctagatca aaacggtatc aaactggaca acttaacgat
     6361 cactggaggg atgagtgaaa agaggacaca tcgtccgtct gatggctcgg ctattggtgg
     6421 atacttagtg gaggggttat tgaataacgt ccatgagcgg gaaatcccta tttttgtcaa
     6481 cgcagatgtg acagacatta agaaaaatgg ggaaacggtc aatgaagtga ctgtacatgt
     6541 tcaaggagaa gaaccaaaag aggtcaccgg aaaagcaatc gtagttacca caggcggttt
     6601 tggtgccagc aaagaattta ttgaaaaata tcgtcccgat ttagctgatt atattacgac
     6661 aaatcaagaa ggatcaactg gagatggtat caccatgatt gaaaaattag gtggacaaac
     6721 cgttgatatg gataaaatac aaattcatcc aactgtgcag caggatgagg gggtcttgat
     6781 tggtgaggtt gttcgcggag aaggagcaat cttggtcgat caagagggga aaagatttgt
     6841 caatgaaatg gatacaaggg ataaagtatc tgcagcaatt acagcattgc ctgaaaaatc
     6901 agcttatttg atttttgacc aaggcgtgcg tgatcgtgcc acagctattg aattttatga
     6961 ccaaaaagga tatgtcacaa ctggaaagac aatggaagaa ttagcagaaa aaatcgattt
     7021 accaaaagaa acactagcaa aaacagttga tggatggaat acggatgttg cggagaaaaa
     7081 agatgctcaa ttcaaccgtg ccacagccat ggaacatgac ttatcgtctc cgaattatta
     7141 tgcgatcaaa atcgcaccag gaatccatta cacgatgggc ggtgtgaaaa tcaatacgaa
     7201 cactgaagta ttagataaag aaaaccagcc aattaggggg ttatatgctg ctggtgaagt
     7261 cacaggtggc ttacatggaa acaaccggat cggtggaaat tcagttgcgg agatcattat
     7321 ttttgggcga caagcgggca tacaagcagc tcgatttgct tcggaaaatg aatgaaatag
     7381 aacgtaaata aaaagaggtt gtgaaatcag cgttttgagc taataccgag ggtcagctga
     7441 ttgaacactg tttagtgaag aggttgtgaa aaag
//
LOCUS       DBBGRF010000095         7153 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000095 DBBGRF010000000
VERSION     DBBGRF010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.096"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(1..1368)
                     /locus_tag="ACIZD4_002791"
                     /pseudo
     CDS             complement(1..1368)
                     /locus_tag="ACIZD4_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1611..2066
                     /gene="tnpA"
                     /locus_tag="ACIZD4_002792"
     CDS             1611..2066
                     /gene="tnpA"
                     /locus_tag="ACIZD4_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HGC5991645.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2331..2429
                     /locus_tag="ACIZD4_002793"
                     /pseudo
     CDS             2331..2429
                     /locus_tag="ACIZD4_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2652..2882)
                     /locus_tag="ACIZD4_002794"
     CDS             complement(2652..2882)
                     /locus_tag="ACIZD4_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HGC5991646.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(3112..3930)
                     /locus_tag="ACIZD4_002795"
     CDS             complement(3112..3930)
                     /locus_tag="ACIZD4_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGC5991647.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            4091..4780
                     /locus_tag="ACIZD4_002796"
     CDS             4091..4780
                     /locus_tag="ACIZD4_002796"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGC5991648.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4794..6296
                     /locus_tag="ACIZD4_002797"
     CDS             4794..6296
                     /locus_tag="ACIZD4_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGC5991649.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            6309..6785
                     /locus_tag="ACIZD4_002798"
     CDS             6309..6785
                     /locus_tag="ACIZD4_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HGC5991650.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6882..6992)
                     /locus_tag="ACIZD4_002799"
                     /pseudo
     CDS             complement(6882..6992)
                     /locus_tag="ACIZD4_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2318 a         1131 c         1294 g         2410 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggatccg atttttggct actgctccga cttgtcctcg ataagaattg tagcgccgtg
      541 atttacgtgt gtatgtcgtt acttttattc ctagcttctt gatcaggcgc tgaactttct
      601 ttttattgat agagaaaccg cggtttctta gttcattggt catccgtaaa cagccataat
      661 ccttgtgctt ctcccgaact ttaagcattt ccgcttcaat ctcttgatct ggatttttac
      721 ggtccaatcg tttttgccag tacataaaga ttgccttagg gaactttaaa gtttctagaa
      781 gctcaactaa tttaaacggt cctcggaggc ttgcgatgat tcgtgcgatt gcttcattcg
      841 tcgttgttgg gcttcctgtt ttcgcagctt cctcaattct tttaaaaagg cattttcaat
      901 ttgaagggaa cggactcgtt tctccaactc ctcgatgcgt tcacgttctt tagacgttgc
      961 tttagttgta gattttttct tatttttggg ttcatttttc ttagacaaga taggtggaca
     1021 tcctttcgtt tttgagagtc catcgatccc accctcacgg aattgacgca tccaactagc
     1081 gatcaaatta gggttgttca tgttaagtgt gttggcaact tcacgatagg acagctcact
     1141 tgttagatat aactctatcg catccagctt aaattgaaca gaatattttt tcttttgtcg
     1201 ctttcttact agaccctctt caccaaattc ttgataggca ttgatccagc gcttcacttg
     1261 tgatggagcc ttaatggaat atttctttgc cagataatca cttccgcctt taccatccaa
     1321 gtaatcatga acgatcttta atttaagttc aaaagtatac ttagccataa aaaataccga
     1381 cctccaaaag ttagattttt tggtctaact tttgggggtc ggtacaaaac ttaaaagttt
     1441 tagacccttt tattttctta atgacttcag tcagttttgt gcgtaaagcg tgcgaaacaa
     1501 gaaaaccgcg cgtttctacg cgtggaagaa gtatctttag cgataaaaac tcctttcgat
     1561 atactagtga gtggctacca accgctcatc agatcgaaag gagttttttc atgtcaaatg
     1621 acgataaaag tttagcatat actcgttgga attgtaagta tcatattatt tttacaccaa
     1681 aatatcaacg aaaagtaatc tatgggcaat tacgaaaaga tcttggaaaa atacttagga
     1741 agttgtgcga aatgaaagat gtggaaatca tagaagcaca tgcaatgcta gatcatattc
     1801 acatgcttgt tcgagtacca ccaaaaatat gtatatccag ttttatgggg tatctgaaag
     1861 gtcgtagtgc ggtactaatc cacgagcagc acgcaaatct caaatataaa tacggaaaca
     1921 aatccttttg gtcgaagaga tactatgtga gtacagtcgg attgaatcaa aagacaaatg
     1981 aaaaatacat ccgtgaacaa gaagctgatg atcgcattcg atatattata agtaaaagag
     2041 agtacgtaga accatttaaa aaataaagag aagtaagtga gtgaagatga gcagttggcg
     2101 gtcttttaaa aatccccttt taaggggcag cgagtgtcga ccccttctag ggggattaaa
     2161 aatacacccg tcctcacggg tgtatgggtt actgatagac ttgattttaa ctggtgtcag
     2221 aaacttatgt ccagaaaggg tgatgaaatt ttggcaattt acggctattc aagaattagc
     2281 acaagcaacc aagattacaa aacacaaatt caaacattag aaaatgctgg cgcagaaata
     2341 atcttcctag aaaatcactg gattatcgaa cacctttgga agtatttttg agttacgtaa
     2401 gtattgatga tctgtctaac ttaatttgac aattaagagt atatttactt cagatggtaa
     2461 ggcaacaaaa taaaatacaa taggcagatg aactaataaa taaaatctgt attaaataca
     2521 gataaattaa tataaaaatc aaaaggatca taaactttta acaagtgatg aaatgggtgg
     2581 aaattgattc ttatagacag tttgtctcat aacattgaag tattttgcaa ttttagcatt
     2641 gaaacacttt tttaatcttc aacgttgttc ttataaacaa gatgattggg aatcttttga
     2701 attaacactg tatagcttag aacacccttt atagaaaaca ttcgcttagc aatcttaata
     2761 attccttgtg cccgatgtcg tttagattca gtaggttcct gctcatcgat catggaaaaa
     2821 atttgaagga tcagatcctt aataaattta tttaagagag gatgatccat tgcttcatcc
     2881 atactcgata aactagtgat aatgagctac acgtttttct ttcaagttga tcaatagctt
     2941 ccacgataaa aatatcttta gataaaatca agaaccgtag gaactacagg gatatttggt
     3001 caataagagc caccgctatt agtaaaaaat aagctatcaa gtatgctctc atcccaagaa
     3061 ttgcctactt caatcgttaa aaaccgttag gtttagctaa gtgggggtag ttcactcaat
     3121 acttttatca ataatagagc gcaaaacttt ttctcttaat tcaactgaat caatattatt
     3181 gttttgttca taaccatgaa ctaatagatc acaaatataa agttgtgata tttttccagc
     3241 taaagatcca ccattaagaa attcttcaat ggctgtttgt aaaactaagt ctgcagactt
     3301 tcctataggt gaatgaatat agttagttat agcaataatt tttgcgccat tttttttagc
     3361 tattttcaat gaatcataag tatctttcgt tttcccagat aaagaaaaaa tgattactaa
     3421 atcattaact gttaataaag aagcgacttg ggcttgaaaa tgagggtcta gtacagcttt
     3481 tgcttgaact cctacgcgaa gaaacatatt ttctaaatca agactagtat ttccactaga
     3541 tcccactcca aatatatata tgttttttga ttgagtgatc attttaatgg cttcattcaa
     3601 tttttcttcg tctaaaagcc taatagtgga atagagagct tctgttaaac tattagcaat
     3661 ttcatcatag tactttacac tagtcggatg ttcttttttt tgactaaagt cttcctttgc
     3721 aatttcaatt tttaaatcag aaaaaccaga aaaaccaatt ttttgacaaa agcgaataat
     3781 agtagcatcg ccaacttttg tgtttttctt aatatcactc atcgtactat aaataatagt
     3841 tttcccagaa tttaaaataa aatcagcgac ttttttttca gacttcgtta aaaatggata
     3901 attttcttta attaaataga tataactcat acaaactcct ctacaatttc aacttttctc
     3961 cattatactc caaaataata aaaaaaactc ctaaatactc catttttatc tttactttta
     4021 tgaaagcgga tgctatattg tttttggagt tattatccaa aaataataaa aaattggagc
     4081 gtttaggata atggataaaa agaggttttt agatcttatt tcaaaaggtt tgattgtttc
     4141 atgtcaagca ttacctggtg aaccatttta caaagaggaa gaaagtttaa tgccttattt
     4201 tgctttggct gctcaaaggg ctggagcagt tggtatacgt gcaaattctg ttcgagatat
     4261 tattgaaatt agaaagtgtg tatcattacc aatgattgga attattaaaa gagattatcc
     4321 accagaatct ccattcatta ctgccactat gagagaagta gatgaattag tagaaaccgg
     4381 tgttgaggta atcgctcttg attgcactct tagaaatcga catgatggac tatctataaa
     4441 ttcttttatt actaaaataa aagaaaaata tcctcatcag ttatttatgg cagatatttc
     4501 tacatttgaa gaaggcaaaa atgcatataa agcaggaata gattttgtag gaactacttt
     4561 aagtggatat actgaggaaa gtaaaaaaca agatgggcca gatatagatt tgattaaaaa
     4621 attggtagaa gaagggattt gtgtaattgc tgagggaagg attcatactc cagaacaagc
     4681 aaaagagata aaaaaaatag gagttgcagg tattgttgtg ggtggtgcta ttactcgacc
     4741 acaggaaatt gcatcaagat ttgttaaagc attaagttag ggggagaaat aaaatgttta
     4801 aaaaattttc acaattagga cgcgctttca tgttaccaat tgctatatta ccagtagccg
     4861 gattactatt gggactggga ggagcgttaa caaatgagag tgctataaat gcttatccat
     4921 ttttagatca accgtggttg catacaattt taagtattat gagttatgct ggaaatgcag
     4981 tttttgcaaa cctagcacta atttttgcaa ttggtattgc tgtaggactt gcaaatggag
     5041 ataaaggaac agctggttta gctggtggag tagcttatct agtatatact gcaactatta
     5101 gtgggtttct tgaacttttt tcagcaaaag atgcaacact agatacaggt gtagtgggat
     5161 caattgttgt tggtggtact gttgcatttt tacacaatcg ttatagaaaa attgaattac
     5221 cacaattctt aggttttttt ggaggatcaa gatttattcc gattgtttct agtttagctg
     5281 caatcattat tggttctttc ttttatttaa tttggccacc aattcaaaat ggtttagtag
     5341 ttgctggtga acaaattgcc caaatgggta gtttaggaac ttttttatat ggttttttat
     5401 tgcgtttaac aggtgctgtt ggactacacc acaccattta ccctttgttc tggtatacat
     5461 ctttaggtgg taccgaaact gtagctggat caacaattgc tggagcccaa aatattttct
     5521 ttgcccaact agctgatcca aaccacactg gtctgtttac ttatggtact agattttttg
     5581 caggaagatt tgcaacaatg atgtttggat taccagcagc atgttatgca atgtatcgtg
     5641 caattcctaa gaaaaatcgt aaaaagaatg gtgggcttta ttttagcggg gcccttacat
     5701 catttttaac tggaattact gaaccagttg aatatatgtt tttatttgtt gctccttggc
     5761 tttatgtgat tcatgcattc ttagatggat tatcttttta ttttgctgat atcttaaata
     5821 ttcgtgtagg gaattccttt tcaggtggtt tgatcgactt tttattattc ggtgtacttc
     5881 aagggaatga caaaactaat tggttaaaat taattccttt tggtattgca tgggcattta
     5941 tatatttctt tgtttttaca ttctttatca aaaaatttaa ggtagctatt cctggaatgg
     6001 aagaagaatc agaagttcat tctgaaaaag taataaacaa aaatacatca ttacatgaag
     6061 agtctcttat cattattgaa gctcttggtg gaaaagaaaa tattgagtct gttgaagctt
     6121 gtgcaactcg tttgcgtgtt gctgttacga atggggagat tattcaaaaa caaacaataa
     6181 aagacactgg tgcaactgct gtcttcgaag tgaagggtgg catccaagct gtttttggag
     6241 ggaaagctga cttattaagt caagaaatca atcaaatatt aggaaaagat aattaggagg
     6301 tttttaatat gtttgaaatt ttcaaaaaga aaaaacaaga aactttttat gcaccttgtt
     6361 ccggaaaaat catttccatc acagaagtaa atgatcctgt cttttcacaa aaattactag
     6421 gtgatggttt tgccgtcata cctgatggtt caaaaattta tgctccattg gctggtcgag
     6481 taacaaatat atttcctact aaacatgcta ttaatataaa aagcaactca ggcattgatt
     6541 atttgattca tattggaatt gatacagttg aattacaagg agagcctttt tcgatttgtg
     6601 ttcaagaaaa tgatgaggtt actcctgaaa cctcgttggt tgatgtggat tttgacaaaa
     6661 taataaaatc tggtaaagat acttctgtta tagttgtttt tccggagaaa aatcagttca
     6721 atgatttaat aatagataat ggtcgaattg ctcatgggaa ttcatgtgga aaaatcactt
     6781 tttaaaaaag tgtatataaa aagctataaa ataagctaaa taggatattt gtcaaatgaa
     6841 gttggtgaac agaaagaact gttttctttc tgttcatttt tttattttat tagtaatgat
     6901 tccccatgcc aaatcatgat ccgtaattta aagttataaa agcttcgaaa tccattggca
     6961 tttcgttgga ataccttgat atgattattc aaatataaaa tatagagaga agagagagag
     7021 ggaagatatt tataaagggc aaagttatgt ttactcaact taggaaatag aaatagatca
     7081 atttatattc tcttgtcaat cgaatatgaa ccttagcact atataccaaa tatagtaaaa
     7141 tgctgaaaga tgt
//
LOCUS       DBBGRF010000096         6173 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000096 DBBGRF010000000
VERSION     DBBGRF010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.097"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            725..811
                     /locus_tag="ACIZD4_002800"
     CDS             725..811
                     /locus_tag="ACIZD4_002800"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGC5991651.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACIZD4_002801"
     CDS             complement(932..1621)
                     /locus_tag="ACIZD4_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991652.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="ACIZD4_002802"
     CDS             complement(1866..2780)
                     /locus_tag="ACIZD4_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HGC5991653.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACIZD4_002803"
     CDS             complement(2762..3142)
                     /locus_tag="ACIZD4_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HGC5991654.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACIZD4_002804"
     CDS             complement(3592..3879)
                     /locus_tag="ACIZD4_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGC5991655.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACIZD4_002805"
     CDS             complement(3899..4123)
                     /locus_tag="ACIZD4_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HGC5991656.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="ACIZD4_002806"
     CDS             complement(4578..4748)
                     /locus_tag="ACIZD4_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991657.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="ACIZD4_002807"
     CDS             complement(4763..5296)
                     /locus_tag="ACIZD4_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HGC5991658.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..>6173)
                     /locus_tag="ACIZD4_002808"
     CDS             complement(5317..>6173)
                     /locus_tag="ACIZD4_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HGC5991659.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DBBGRF010000097         6167 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000097 DBBGRF010000000
VERSION     DBBGRF010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.098"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            90..710
                     /locus_tag="ACIZD4_002809"
     CDS             90..710
                     /locus_tag="ACIZD4_002809"
                     /inference="COORDINATES: protein motif:HMM:NF037736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGC5991660.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFFRNSN"
     gene            953..1513
                     /locus_tag="ACIZD4_002810"
     CDS             953..1513
                     /locus_tag="ACIZD4_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HGC5991661.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            2402..3169
                     /locus_tag="ACIZD4_002811"
     CDS             2402..3169
                     /locus_tag="ACIZD4_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HGC5991662.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            3195..3740
                     /locus_tag="ACIZD4_002812"
     CDS             3195..3740
                     /locus_tag="ACIZD4_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991663.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            3741..4307
                     /locus_tag="ACIZD4_002813"
     CDS             3741..4307
                     /locus_tag="ACIZD4_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991664.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            4322..4570
                     /locus_tag="ACIZD4_002814"
     CDS             4322..4570
                     /locus_tag="ACIZD4_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991665.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            4589..4828
                     /locus_tag="ACIZD4_002815"
     CDS             4589..4828
                     /locus_tag="ACIZD4_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991666.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            4845..5429
                     /locus_tag="ACIZD4_002816"
     CDS             4845..5429
                     /locus_tag="ACIZD4_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991667.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            5536..5817
                     /locus_tag="ACIZD4_002817"
     CDS             5536..5817
                     /locus_tag="ACIZD4_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGC5991668.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            5807..6148
                     /locus_tag="ACIZD4_002818"
     CDS             5807..6148
                     /locus_tag="ACIZD4_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGC5991669.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
BASE COUNT         2315 a          801 c         1275 g         1776 t
ORIGIN      
        1 gaaatatttc cctttaatta atcaaatttt ttataaaagt aatatataaa ataaattgct
       61 tgaagtatta tatttagata tcataattta tggaagaaaa attaattaaa aaggatgaga
      121 ttataatggg gttactggtt ccgagagcta atacttatac tataccttta acgaaacgcc
      181 aattaattgc taaaagatat caaaggatta ctagagccat caatagagag ttttggaatt
      241 ctgaaagtga tactgctcac agtttatacg taggttctta tgggagagga acggcaatta
      301 gtactagtga tatagatata atagttgaat taccgatggc agaatttgac agattcaaaa
      361 attatttatc aaatggcccg tctaagttat tacaagttat aaaaaacgca tttcaggaaa
      421 tactaccaaa tagtgatatt agagctgatg gacaagttgt taaaataaat ttccatgatg
      481 gaatcaaatt tgaaatagtt ccagctttta atgaaaaaga ttattggggt gagtcaaaag
      541 ggtttattta tccagattca aacatgggag ggaactggaa agctacaaat cccaaaaaag
      601 agcaagaagc catgaaatta aagaatacaa aaagtaataa tttattatat gctacgtgta
      661 aacattttcg acatgtacga gatacagaat ttttcaggaa tagtaattga cagtttcgta
      721 tatgaggcta tgggaaattg gaaattcgtt gaaaataaca gtgggggtca aaacattagt
      781 tctgtatctt atgagacagc tttattagaa tactataact cacataaagt tatgggcggt
      841 ttaaatttat actctcctgg aagcaatcaa tttgttaatt ctgatagtag tatcatatgt
      901 ttagaaaaag tattaaaaaa aatagcttta taaagtttta tggaggaaca acatgggaga
      961 cgaaaaaaag cgcttggaag ttcaattacg tgaagcatat ggacgagtaa cgtatactta
     1021 caccactcat ttaaagcaag ccgataatat tatttctgac aataaaattt taaggtgtct
     1081 tcaaattggt ttgtcagccc ttactactgg aggggtactt agtaccatta ttactgataa
     1141 tagtgagtta acctttgttg ctggattatg ttcaacaatt tctcttggat taaacttata
     1201 ctttaagaat tttgatcttg ctgaagaagc taaaaatcat caaattgttg ccgataaatt
     1261 atggttgatc agagaagaat acgtaagctt actaacagat ttaaatcgtt taagtgttga
     1321 agatattgtg aaaaaaagag atcaattaat gaacgaaact catgaagcat ataaaaatgc
     1381 ccctaaaaca aatagtaaaa gctatgaatc agctcagaaa gcattaaaat ctgaagaaga
     1441 gcaatttttt acagaagagg aattggataa gatgttacca gagcatctta gaaaaaagag
     1501 ttctaaatat tgaactcttt ttttatgctt aaaattctct tgtaattttt ctattcatct
     1561 atatttaaga agaaatatga tgatagaaac atctcctaaa gccaccgcaa gccgttctaa
     1621 gcatagctta gcccgacatt gctagatatg ctcatctcac catgaacgtt tcctaaagcc
     1681 accgcaagcc gtcctagcca ttgcctagtc cgacatcgct agattagtgc atctcgccat
     1741 aaaagttttc taaagccacc gcaagccgtt ctaagcatag cttagcccga cattgctaga
     1801 tatgctcatc tcaccatgaa cgtttcctaa agccaccgca aaccgtccta gccatcgcct
     1861 agtccgattt tgcttgatcg gttccatttc tgtttattta gtgggtcaac accgtaatct
     1921 taaatagcca tcgcctattt aagattacta ggtctgcttt gaaggtaaaa agtctttcat
     1981 tcttcaagac ttttaggctt tcaagctacg cctgaaagca ttgaaattca tcgctcttta
     2041 tttggttttg ccatttataa ttccttacgc ccattatctt tttcgcctgt cataccttgt
     2101 cagaagtgtt tagagcttat ctcatctttg gattaataca agtggcgtaa atttttttct
     2161 aaacgcaagc gttacgaaaa taatttactt aaacacttgt attaatccgg cagataagaa
     2221 cgcattctaa tcactcccga caaggcaaga caggcgaaaa agataaataa atgaacgaaa
     2281 ggaagaaaca taaaatgcaa aaccaaatag cgatgaagaa aaaaccacct ccctctaaaa
     2341 caatccaaac aaaaaagaat tttgaaaaac caaaaatcaa aaacagaaag aagcgttcaa
     2401 catgagagat agaattttag aagttaatca agaaatggta aacaagttaa caaatatcag
     2461 tgggaactat gaaaagtacg atggtacttt acttgataac tatatttttc acgatacaca
     2521 aaatatcaga attggcagaa gtaaaccgag agcgttcatt ctcatcaaag agaaatattt
     2581 gaatgaatgg aatagcacct atgaaatggt tatgactgat aactttgaaa aggtattgga
     2641 tttcagaaat gctttgttgg gttctgatat gggaaatagc agtcttgaat ctattgaagt
     2701 tgaaaacaag accgagaatg aaggtgaagg attgattaag aatgtcttga aaatcgaaca
     2761 aaaatatatc agtgaagata gaagttttta tagagtcaca agctcggttg gtctagcaaa
     2821 ctttgctact aacttaattg gaaacaatgc tagtgaatct ttgctagtga tgtgtctgaa
     2881 tacaaagaat gaggtcattg cttatagcga agttttcaaa ggtggaatta atcaatcagt
     2941 agcgatacca agagagattt ttcaactagc tttgctaaac aattcagcaa aaatcgcagt
     3001 atcacataat catccgagcg gatatgaatt tccaagtgaa aatgacaaaa gttttactac
     3061 gaatttgaaa aacgcaggaa aaacaattgg tattgaattg ttagaccata tcatcgtaac
     3121 aagtaaaaac acaagctatt actcatttca agaaaatggt tctttataaa aattagagaa
     3181 aagaggaaaa caagatgggc gaaagaacac aagcgttaat tacagtcaaa tatggtaaca
     3241 gcaaaacgaa agcaagcgtg tcgattcatt atcagtgggg gtatggtcga tatatgctga
     3301 tggacgtatt gaatcaagga atttatttaa tcaataaagc atacgactta cgagataaat
     3361 caagagaaga attagcaaaa ggaatctttg atagaagtac aggagttatc aattttgtca
     3421 cctatgaatc tggagtgagt gcttatgatg aaacagggtt tggtgggcgc tatgaacctt
     3481 atcaagaaac gattgaagat gtgatgaagt tttcagataa caatgatggc tatgctcatt
     3541 tagagatggt gttcgatgaa aatggattta gtctagatga taaaaccaga ttgcgattgt
     3601 ttgattttga gggtcaacag ataggactaa acaagttttg tgaaagcgga aaagagtttg
     3661 ctacgaaaga ttttattaag ggatacagat tattgctaga aaattatgga ataaacctag
     3721 aagaagagag cgtgaaataa gtgtttgaaa aaagaaaaga ccagttccct aatttagaag
     3781 cgaaaagtca aaaagtgatt gatggtgaaa tgattgaatt attccaaaaa agttatggaa
     3841 ccatagaaac taccgcaagt tgcaaatact actttcaagg aaagagaaac acgtttaaag
     3901 gctttgccga ttctgatgaa gaattggcaa agaaaatcat tgattggctt gtcagcagtg
     3961 aacacgtagc aagagaagat accgttagaa caacgattaa tggggaagtc ctaacaggta
     4021 ctagatgtgt ttgttgtaat catgaatttg tagaagatga aggttgctac cgaatcaatg
     4081 aatatggtga ttttatttgc cagagttgcc acgagataga atttccaacc gaaagaagtt
     4141 ggtttgaata catgctacaa gattatgaga tggaaacaga aaatggtgaa gtagtttttt
     4201 gtaccaaaga ggaattgagt aagagaagcg atgatgaaat tgaagattgg tgtgtgtggt
     4261 tagtagggac agatgattgc gttgcatatt acacaacagc agaataggag tgtgaatcag
     4321 catggaagga atggatttta tagatcatga agatttgatt gattttggtt atacatggaa
     4381 aggaatggta ggtattagca gaagtcttgc taatgccttt tacgaaagaa attatgcagt
     4441 ctatgtcctt tatgatgaca atacagaaag ccttgttgat gaagagtata aattggattt
     4501 agagaatgtt ttatatggga tagaaaaaga agatttagca aaatatattt tttcatggtt
     4561 gggtcaataa acgaaagagg gtagcaacat gacaaaattc aaaagtaaag gtatgcaatg
     4621 gtgttcttat tattatgttg ggaatgatga agagcttttg agaaaagcca aacaaaaagg
     4681 ttatccagat aagatgttaa aacagattgg ctattacatg ccagaagaga gaatagaaaa
     4741 agaatcttgt aaggttcttt ttgatagtga acagctatta gttttgttaa ctcaaaataa
     4801 attgatttgt caatttgaaa ataattaata tggggtgaag aaccatgaat gagaataaga
     4861 tggtattaag tgaatacgca agattgagaa ccattaattg gttgaatggt atgcaaagta
     4921 gtggcgcttt tgatggattt gatgaggaga atatggactt tgaaagttta tcgaatgagg
     4981 atattagata ttattttatc gaatggtatt ttacagaacc agatgaagag gtggaagatg
     5041 aaccagaatt aattttagaa cgtcaaagaa ttttattcag tgaacaagat agtaagaggt
     5101 tgtatggttt atatgactta caactgaaag gattaaaagc gcagtatgtt gctgatagtt
     5161 acgatgatat ggtagaacag ggggcagata gggttgtcac ttattcagaa gatgatgaag
     5221 aggaatggga aaactattca gatgatgaga tatgctttaa tgatgggtat atgcctattg
     5281 aaatcaccga agaagaatat gataaagtgt cggatagcga tgagattggt atgtgtacgg
     5341 ttgtaagtgg attggatata gatgtccaaa gagtagaggt tgcataccag aagatgaaag
     5401 aacgtataaa aagtaaagta gaatcttgat ttgattggat tgtttgcaaa gtagctaatt
     5461 aagagtataa tataatcata aatgtagtta atggatataa taatgagtat attatactca
     5521 aaagaggtga acgaaatgaa ggtaaaaaat ccaaaagaaa aaagcagaat tcaagtcgga
     5581 atagacaagg atttaaaaga aaacgcagaa atgatattgg aagagctagg gttaaatcca
     5641 acaacagcaa tcacaatcct ttataagcaa gtggtcgcta gaggtgagtt tccagtagag
     5701 ataaagctaa gcgaagagga aaagcaagga atcagattgc aacagctaac tatggatatg
     5761 ccagttgatg ttctagatac agatgaaaag ttagaagagt ggttcaatga agcctaatga
     5821 gatagtaacg gtctatgttg catttacaga taaaaatggt ggtaaaagaa gacctatttt
     5881 ggtggttagt gataaagaag atagagtaga attttttgga atcacaagtc aatatgagaa
     5941 taaatcagac caaataaaga gagtgtattt tcctattgca gaatgggaaa aagtaggtct
     6001 aaagaagcaa tcatggattg acgtagggtc tttaaaggct attcccaaaa gccgagagaa
     6061 catatcattt aaaaaggttg gtatgctatc agctattgat acgaaaaagc taaataggtt
     6121 tatcgagaga ttacaaagaa aagtctaaca aggcttttct ttttttg
//
LOCUS       DBBGRF010000098         6064 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000098 DBBGRF010000000
VERSION     DBBGRF010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.099"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(136..1098)
                     /locus_tag="ACIZD4_002819"
     CDS             complement(136..1098)
                     /locus_tag="ACIZD4_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5991670.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1100..2539)
                     /locus_tag="ACIZD4_002820"
     CDS             complement(1100..2539)
                     /locus_tag="ACIZD4_002820"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HGC5991671.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2724..4670
                     /locus_tag="ACIZD4_002821"
     CDS             2724..4670
                     /locus_tag="ACIZD4_002821"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGC5991672.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4934..5806
                     /gene="scrK"
                     /locus_tag="ACIZD4_002822"
     CDS             4934..5806
                     /gene="scrK"
                     /locus_tag="ACIZD4_002822"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGC5991673.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1917 a         1043 c         1071 g         2033 t
ORIGIN      
        1 tttctccact ccaaaaaagt ctaacttttg ggggtcacta caagttgaca actccttttt
       61 gtttacaaat caattggata tctacaaatt gtattttcta acgaatttta tagacattaa
      121 aaaattaatt taacgttaaa tacttcctcc agaaagtatt gagattggta aaatataatc
      181 cttatttgtc ttttcgcctt taattttttt cagaagaata tcaacaataa gacttgcaat
      241 ttcatcaatt ggttgtctta ttgttgtcaa ttgtgggaaa aatttctcaa taaaagaggt
      301 accatcgtat ccaataattt ttaaatcttc tgggatatta agtttaagtt gatgagcaat
      361 tttcatagtg agaatggctg ttaaatcatc agaaacaaaa ataccatctg gtttgtgatt
      421 tataatagtt gactttattt ccatttcacg acggatagta gacagattat taggaatttt
      481 gaaaattttt ccatttggat tttgaaaaga aaaacctagt gcacgtaatt ctgtgggaga
      541 atccgtgtta tcatttcctg taatcataat ggtattttga caaccatttt tttgtaaagt
      601 cttagctgca agttttcccc cttcaaagtt atctgaagaa acaatggaaa cattaggagc
      661 taaatttcta tcaaaagcaa caataggtgc tctcacacgc tcataatcag caattccaag
      721 attatggctt gatgagatta tgccatcaac ttggttggct tcaagcattt caatgtattc
      781 tctctcttta gcaggatcat tttgactatt gcaaataatc gttttatatc catgtttaaa
      841 taactctatt tcgagatact caatgagttc agagtaaaag atattactaa tattaggaaa
      901 aataagacca ataagctgag gtgactttcc ttgaagtcca cgtgctaaat tatttggttt
      961 ataaccaaga gttttcatag cttcatgaac tttttgtttt gttttttctg ataaatatcc
     1021 cttattatta atgacgcgtg aaacggttgt tgggctaact ccagctaatt cagcgacatc
     1081 agttaatttt gctaccattt taatatttta attcaaagta ttttccagta ggttcgcctg
     1141 atttgatttg aataccattt tggtgatttt cagggaatac acgactagta aacacttttt
     1201 ctcctttatt aataaaaatc tcaatgattg agttatctac aaaaatgtta gcagttgttt
     1261 ctttagtatc aattgagcat tcacgaatcg taccaaagtc agtggcatat tgaatgcctg
     1321 ctttgctgcg atctaaaata atttttcctt ctttggtatc tacaatcaag ctaagtccat
     1381 ttcctttact atcagagaaa agaagtaact ccgatttctg atttggagga aaagttagtt
     1441 caagctcata agtattattt gtttctgctt ttgctgtaaa ttgttcagaa ctagcacgta
     1501 atgatgtaat agcttctact ggatattggt aaagtttacc atcttttatt gaaagttctt
     1561 ttacaagact cattgctccc tgataatcat acttatcagt tggataatcg atatcaggta
     1621 gtccaatcca actgacaatc agagcacgac catcaggagt attgaatcct tgagtcgcat
     1681 acgcttcaaa tccataatca agattttgaa tttctgaagc gcccacaagt tttacttttt
     1741 ctatgtcaag cgattgacag atcttaaaag tattcggata gatattccca taatttagct
     1801 cagatttatc caacccttga ggacaataaa tgagaacagg ttttttgtct acaaatacta
     1861 gatttggaca ctcaatcatg tattctgaac cagtgccgcc aaaatcaagg ttgccaactt
     1921 cctcccatgt ttccacgtta ttgtcatccg ctttgtaaag tttgataaag cctgattttt
     1981 ctaaattttg tgctccaaca atcgcataca attgtccttc ataattaaac atttgtggat
     2041 cacgaaaatg atcagttaca tcagcaggtt tatgaataag aacattctca cctttcgtaa
     2101 tgttgtagtc tttatccatc catgctccga tttgaagtgt atcacgttcc caattttcat
     2161 ttcgaacgtt tcctgtatag agtaagaata gattcccctc tatttcatat gcagaaccgg
     2221 aataagcgcc gtggctatct cgttttgtgt ctggaagaag ttctgctcct gttacatgaa
     2281 aatgaactaa atcatctgat tcattgtgta cccattcttt caacccatga gcagctccaa
     2341 atggccaatt ttgataaaaa agcgtatatt ttccgttaaa aaaagaaaaa ccattaggat
     2401 cgtttaacaa tcctgtttta ggttcgatat gatagctagc acgccaaggt gatcgtttta
     2461 cattatcctt aattttatcc atctcatctt tagtccaatc agaataagca cgatatcgta
     2521 tttctcgagg taagttcata ttttactcct tcaatttatc tttttacaac tagtatggta
     2581 aacgttttcc gttgaaaaat caatcatttc atttaaaaaa ataaactata tgacaaacgt
     2641 ttgacatatt tttaagatat gctaaaataa atttgcattt cagtgaaccg ttttcacgta
     2701 aaaataaaaa aggagtgatt cgaatgaatt acagtaaagt agcttccgac gtaatacaag
     2761 cggtcggaaa agataacctt attgcagctg cacactgcgc tacacgtctt cgtctcgtac
     2821 taaaagatga cacgaaagtg aatcaaaaag ctttagacga aaatccagat gtgaaaggca
     2881 catttaaaat tgatggacaa tatcaagtga ttatcggtgc aggtgatgtt aatttcgttt
     2941 atgacgaact tatcaaaaaa actggacttt cggaaatttc aacagatgat ttaaaacaaa
     3001 ttgctagtaa agataaaaaa ttcaacccca ttatggcatt aattaaatta ttatcagata
     3061 tttttgttcc aattatacct gcccttgttg caggtggttt attaatggca ttacaaaact
     3121 ttttaacagc tgctggactt tttggaccaa aatcaattga agaaatgtat cctgcgattg
     3181 aaggtatttc ctcaatgatc caactgatgt ccgctgcacc attcatgttc ttaccaattt
     3241 tagtaggtat ttcagctgct aaacgttttg gagcaaacca atttcttggt gctgcaattg
     3301 gtatgatcat gacaacacca gatcttggtg gctcaactga atattggaat atttttggtt
     3361 atcatgtttc acaaacaaac tatgcttatc aagttattcc agttttagca gctgtttgga
     3421 tattatctat attagaaaaa ttctttcata aaaaattgcc atcatctatt gactttacat
     3481 tcacgccatt attatcagta atgattactg gatttttgac tttcacagtt attggccctg
     3541 taatgttatt gttgtctaat ggaattacag acattattgt ttggctatat aacactactg
     3601 gatttattgg aatgggtatt tttggaggaa catattcact tatagtcatg actggtttac
     3661 atcaatcatt tccagctatt gaaactcaat tactttcagc gtggacaaat ggtatcggac
     3721 atggagactt tatctttgta gttgcatcta tggcaaacgt tgctcaaggt gctgcaacat
     3781 ttgccatttg gttcttaact aaaaattcta agacaaaaag tcttgcttcc tctgcgggtg
     3841 tctcagcact tcttggaatt acagagcctg ccttgttcgg agttaactta aaataccgct
     3901 ttccattctt ttgtgcttta attggttcag gaattgctac agcagtagca ggattactta
     3961 aagtagttgc tgtttcactt ggttcagcag gtttcttggg atttctttca attaatgcaa
     4021 catctattcc attttacgta ttgtgtgaat tgattagctt tgtagttgct tttgcaatta
     4081 cttacttcta cggtaaaaca aaagctgctg gtatctttaa agcagaagaa attgctgaac
     4141 aaacaccagt taattcttca aaagtagcaa caacagatcc aatatctact gatgttgaat
     4201 caacacaaac aaaagtttca tcagaaacaa ttgttagtcc catttctggt aaagtgatta
     4261 gtctttcttc agtaaatgat ccagtctttt catcagaagc tatgggaaaa gggattgcca
     4321 ttaaaccaaa tggaaacacg gtccattctc cagtagatgg tactattcaa ctcacgtttg
     4381 aaactggaca tgcttatggt attaaatcaa ataatggtgc tgaagttcta attcatattg
     4441 gtattgatac tgtatcaatg ggaggaaaag gatttacaca aaaagttact actaatcaaa
     4501 aagttagaaa aggcgatatt cttggagcat ttgaccgttc aatgattgag aaagaaggtc
     4561 ttgatgatac aacaatgatt attgtgacca atacttcgga ttattcagaa gtaaatatag
     4621 tagctgaaaa tacagtcact gagggtactg atttacttga aatcaaataa atatatttcc
     4681 ctgagtaaag atggaatttt ctttccaaaa tcaaataata tagattaatc aaatatttga
     4741 gaataacatt ttatttaatc ttttcatata tcaattgtat gaaaaattat tagaatttta
     4801 aaaaatgata aaaattcaaa aagaaaaaat agtagttatt tacttgtcat gttactaaat
     4861 aaaaaaataa tttaaatatg atatatagtc atttatttag tgatttcatt ctaaaataaa
     4921 gggagaaatg tctatgctat acggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc
     4981 cattggcgat gaagaaatga cgatcaagga aagagtgagc tttccgacaa cgacacctga
     5041 ggaaacaatg cctttagtca ttgacttctt caaacaatac caagcagatt tagcagggat
     5101 tgggattggc tcatttgggc ctatcgatat ccatcgcgat tccgccactt atgggtacat
     5161 tacctcgacc ccgaaattgg catggcaaaa ttttgatttc atcggtacca tgaaaaaaga
     5221 atttccgatc ccgatttctt ggacaacaga tgtcaatgcg gctgcctatg gtgagtatgt
     5281 cttcggcagt ggcaaaggat tgagcagtgt cgtttactat acgatcggta cgggtgttgg
     5341 cggcggtgcc ttacaagaag ggcgctttat cgaagggttt agtcatccag aaatggggca
     5401 tatgctcgtc gtccctcatc caaaagatga ctttgctggc agctgtccat ttcatggcaa
     5461 ctgtttagaa gggatggccg ctggacccgc catcgaaaaa cgcttaggga aaaaaggaca
     5521 agaggttgca gaagatgatc cttattggga aatcgaagcc tcctatattg ctcaatgtgc
     5581 ctacaataca accttgatgt tttctccaga tgtgatcatt tttggcggtg gtgtgatgaa
     5641 acaacgccat atgctgcaaa acgtccacga cgcatttgca aaattggtca atgggtatgt
     5701 cgaaacacct gagttaagca aatatatcgt gaccccagca ttagaagaca acgctggaac
     5761 gctcggttgt ttggcattgg ctcgagaagc ggtcttacat tcataaacga aaaaaggctc
     5821 ttcgacattt agtgttggta gagaaagata caactgaaaa tttagtcata accagttagg
     5881 cagagtgctt aactggtttt tgttttactt ggaagatcaa gccttgaatg agataaattc
     5941 ttgctcgaaa gttatggaaa tttcgatagc cgtaggccac ttgtattgtg caatagtttt
     6001 ttacaaaaaa aagggggtgc ggatattttt ttggaccttt ttaacaaata tatctttgct
     6061 tctt
//
LOCUS       DBBGRF010000099         5683 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000099 DBBGRF010000000
VERSION     DBBGRF010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.100"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..109
                     /locus_tag="ACIZD4_002823"
     CDS             <1..109
                     /locus_tag="ACIZD4_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGC5991674.1"
                     /translation="YIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            237..317
                     /locus_tag="ACIZD4_002824"
                     /pseudo
     CDS             237..317
                     /locus_tag="ACIZD4_002824"
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            324..1451
                     /locus_tag="ACIZD4_002825"
     CDS             324..1451
                     /locus_tag="ACIZD4_002825"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC5991675.1"
                     /translation="MSREYYNRIEKGKQPLNDELREIIEKQIERFNPQEPLFLLIDYF
                     RVRFPTTDALAIIRDVLQLKSNYMLYEDYGKYGYESKYVLGDINIMCSMQEHLGVLLE
                     LKGKGCRQMECYLLAQERSWYDFMLDCMTAGGVMKRLDLAINDKAGILDIPKLKEKYK
                     AGECMSYFRMQKDYSGTEKCGSDLPKNTGETLYLGSTSSELYMCAYQKNYEQYVKNGT
                     EIEDTEIKNRFEIRMKNERAYYAVVDLLTYRDAERTAFSIINHYVRFVDREDDKPKSQ
                     WITNDDWAWFVGENREPIRLTTKPEPYTLQKALHWLQRQVAPTIKMVQALDRENRTTI
                     LKDMIEQAELKDKHKHLLQLEKSTIEERIDTAVPQENDGIF"
     gene            2440..2649
                     /locus_tag="ACIZD4_002826"
     CDS             2440..2649
                     /locus_tag="ACIZD4_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HGC5991676.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            2761..4374
                     /locus_tag="ACIZD4_002827"
     CDS             2761..4374
                     /locus_tag="ACIZD4_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5991677.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            4403..4756
                     /locus_tag="ACIZD4_002828"
                     /pseudo
     CDS             4403..4756
                     /locus_tag="ACIZD4_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359794.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         2036 a          828 c         1231 g         1588 t
ORIGIN      
        1 gtatattcct ataaaagata ttatcctaca ctttgaaaaa tacgattatc gttttcattg
       61 gaatagtgat aattcagtta ttgaaatttg gatacctatt caagattaga agcaatttta
      121 tatccataca cacaaagcag ttagtcttag gattgactgc tttttctata cagattttta
      181 atgacaggca attatcaatt atggtagttg ccttttttga ttggaggaat tgaagaatga
      241 atgataaaaa ctttattgaa gaactaagac aaaagcgtga ggaatacgga gtaacacaaa
      301 caaggcttgc tgttgcctgt ggtatcagcc gtgaatatta caaccgcatt gaaaaaggaa
      361 aacagccatt gaatgacgaa ttaagagaaa tcatagaaaa acagattgag cgtttcaatc
      421 cgcaagaacc actattctta ttgattgatt actttcgtgt ccgctttcct actacggacg
      481 cattggcgat tatccgtgat gtattacaac tgaaatctaa ttacatgctt tatgaagatt
      541 atggaaaata cggatatgaa agcaaatatg tacttggcga catcaatatc atgtgttcca
      601 tgcaggagca tttaggtgtt ttattggaac tgaaaggcaa aggctgtcgg caaatggaat
      661 gttatctgct ggcacaggaa cgctcatggt atgacttcat gctggattgt atgacggctg
      721 gtggtgtgat gaaacggctt gatttggcta tcaatgataa agcaggaata ttggatattc
      781 caaagttaaa ggaaaaatac aaggctggcg aatgtatgtc ctacttccgt atgcagaaag
      841 attacagcgg tacagaaaaa tgcggtagcg atttaccaaa gaatacagga gaaaccttat
      901 atctcggttc aacaagtagc gaattatata tgtgtgctta tcagaaaaat tatgagcagt
      961 atgtcaagaa tggcacagaa attgaagata cggagattaa gaaccgtttt gaaatacgca
     1021 tgaagaacga acgagcctat tatgcggttg tagatttact gacctatcgg gacgctgaac
     1081 gcaccgcttt ttctatcatc aatcattatg tccgctttgt tgacagagag gacgacaagc
     1141 caaaaagtca atggataaca aatgatgatt gggcatggtt tgtaggggaa aacagagagc
     1201 cgatacgctt aaccacaaag ccagagcctt acactttaca aaaagcgttg cattggctac
     1261 aaagacaagt cgcaccaacc ataaaaatgg tacaggcatt agacagagaa aatcgtacaa
     1321 cgatactgaa agatatgatt gagcaggcag aactaaaaga caagcataaa catttattac
     1381 aattagagaa atcaaccata gaagaacgta tagataccgc tgttccacaa gagaatgacg
     1441 gtatttttta atgtaattga aaaatttcag atttagtcag caaagagctg ttttcattcc
     1501 ctatgtgaag tgaaagaaga aaaataaatt ttttattaaa tctgcaacaa aatggctact
     1561 tgcgtacaga tatggtgcga gaaaaggaaa tctaaacttt ttttgaaaat aggtcattaa
     1621 atcggggctt gctgtcccta tatgaagtga aagaagaaaa aagttttgaa aaaatgacgg
     1681 aaattcgtga ttagtggaca gtcttctgtg aaaagaggaa aaacatcatc attttgtatt
     1741 caaacaggca ttagcagttg agtgttgatg tgaaaagatg aaaatacttt gttctcaact
     1801 taacaattta aggtttccgt tccctatatg gtgcaaagaa aatatttcat tctattgttg
     1861 gcagtaacgg tatggtttgg gtagttaggg tgtgaaaagg aaaatattct tttttcatca
     1921 tcaacttagc aaaatgacat tttctatccc tatatggtgc atgaaaagaa gttaaaattt
     1981 ttccatttaa acttagcaaa tggacgtttg ctgtacagat agtagtgaaa aaggagaaaa
     2041 tcaaccgttg attgccaaaa tgaaccgttc catttgtact aataatggaa aaagttttgg
     2101 attttggtta cgtttctcct cttttccaac gcgatatata ggaaagacga tttttttctt
     2161 tcaatcgttc tttgacaact gaataaagct attcaatacg tttgacagac agctagccgt
     2221 tgaaacaaat acgccacgac ctttcccctg caagagcgag cgaaaaccta tttgtgttct
     2281 tgtaaaagat ttgtcctctt ttatcgccat gacctgtact gtcagataat gatactcccg
     2341 tacagccaca gcttgagcat taagagcgtc gcacgcaatg ggtacggcta cataagaact
     2401 atgcagaggt ggaactcctg tgggctatga caaaagccgt tgaattgctt agaaagattt
     2461 tacagaaagg gggtatgtgt tattgataat gctgtaaaaa caattcaaaa gaaaaatggc
     2521 aagtgtggca ttggcaacag aggaaagaca aagattgtag taaaagagca tttttccgaa
     2581 aagggcaaaa caatggaaga acttctaact gatgtcatgc tggaaaaagc aaagcagaca
     2641 atcgcataaa atcggtgcag ttgtaagaaa tagattgaat gacaaaaagt acccgtgtta
     2701 tactttactt gcaagcaggt attgtaaaca cgggttagtt ataaaggagg ataactgaca
     2761 atgaaacaac agatttacaa tactgcactt tatcttaggt taagccgaga tgatgaatta
     2821 cagggcgaaa gttccagcat taccacacag agaagtatgt tgcgtttata tgcaaaagaa
     2881 catcatttga atgtcattga tgaatatatt gatgacggct ggtcgggaac aaattttgac
     2941 agaccgagtt ttcaaagaat gattgaggat atagaggcag gaaaaatcaa ctgtgttgta
     3001 acgaaagacc tttcccgtct tggcagaaat tatattatga caggacaata tacagaattg
     3061 tatttcccta gtcataatgt ccgctacata gcgattgatg acggtgtaga cagcgaaaaa
     3121 ggcgaaagtg agattgcacc atttaagaac atcatcaatg aatgggtggc aagagataca
     3181 agccgtaaag tcaaatcagc atttaagaca aagtttgcgg agggggctca ttacggtgct
     3241 tatgctccgt taggatataa gaaacaccct gacatcaaag gaaaactgtt ggttgatgat
     3301 gaaacaaaat ggattattga aaaaatcttt tccctagcct atcaaggtta cggaagtgca
     3361 aaaatcacaa agcagttaag agcagaaaaa gttccgacag cgtcatggct aaattttaca
     3421 agatacggta cttttgcaca tatctttgag ggaaaacccg aaagtaagcg ttatgagtgg
     3481 acgattgctc atgtcaaggc gatattgaaa agtgaggttt atatcggaaa cagtgttcac
     3541 aatatgcagt ctacggtatc gttcaagagc aaaaagaaag tgcgtaagcc cgaaagtgaa
     3601 tggtttcgag tagaaaacac tcacgagccg attattgaca aggaagtgtt ctatcgtgtg
     3661 caggagcaga taaaatcaag acgcagacag acaaaggaaa aggcaacgcc gatttttgca
     3721 gggcttgtca agtgtgcgga ttgtggttgg tctatgagat ttggaacgaa taagacaaat
     3781 aaaacgcctt acagttatta tgcttgcagt tactacgggc agtttggcaa aggtaattgt
     3841 tctatgcact acattcgtta tgatgtgctg tatcaagccg tattggaacg cttgcagtat
     3901 tgggctaagg cagtacagca ggacgaagaa aaggtattga acaagataca gaaagctggc
     3961 aatgcagaga gaatacggga aaagaagaaa aaggcaagta cattgaagaa agccgagaac
     4021 agacaaaatg agattgaccg tttatttgcg aaaatgtatg aagatagagc ctgtgagaag
     4081 ataacagagc gaaattttgt gatgttgtcc agcaagtacc aaaaagaaca gatagaactg
     4141 gaacagcaga taacaagcct aagagaagaa ctaagtaaaa tggaacagga tatgataggt
     4201 gctgaaaagt ggattgagtt aatcaaggaa tattccgtac caaaggaact gacagcacca
     4261 ttattaaatg ccatgataga aaaaatcctc atacatgaag caacaacgaa tgaggataac
     4321 gaaagaatac aggaaattga gatatattac cgatttattg gaagagttga gtaatcaaca
     4381 agagtaatat ttttaactaa gggaaaccgg tattaatatt ccagatattg aaaaactaat
     4441 gaatattgcc tatcttggta aggtcactgt tccttacctt atgtacggag aagattataa
     4501 gaatatactt ccaaaagatg aaagagttag cgattttaaa aagataaatt cttttagtat
     4561 gggattaagg atgaggaaaa ttaggaaaga ttattatcta gaaagggagg agtttggaaa
     4621 gcttttttct ccttcaattt caaaatggtc catagatagg tatgagaatg gtagagatat
     4681 acccaatact aatcgaatta tccaatatgc ttatatagga aatctttctt tagaattttt
     4741 gatttacggg atataaaaat agtttacgtc gatacttatt aagttatcga cgttttttat
     4801 tatagaaaaa atttataaaa ggaggtttct tgatatgata agaaacaaaa agggtttgtt
     4861 gaaagttgct ttactggcag cttttttcta agtaactttt tgacaagctc aatggcaaca
     4921 caagcggaag aagtaataca agaactaact gttatgaata acagctagat aaaatgggct
     4981 atgtatgtta tccaacaatt tagtaatcac tagaagccta gcgaaagttc gcttgataag
     5041 ttatagatga gtattgattt gtagtgtttc caaatcaaaa gggtacagag ccacatgaaa
     5101 tatgttgtcc tctgcagcgt caggatggga atccatacca tggagattcg gagatctgtg
     5161 agggaatact tacgtggtta atatgtcagt tgtgttggac gtagtaatgg tcatagtggg
     5221 tagattgact gaattcttat atgagaaaat gaaaccaaca agaagatagg gttatttata
     5281 cagaattggg gatcttttct ggaaaagtaa tcggataatg cgagattcgt acggtctttt
     5341 ttaaatttct ctaaaaaaaa cggcatcgaa tgggttgggt gattgataag caatgaatca
     5401 tagactgata tagaataaaa aatgattcta tttatctttt tacatctatc gttttttcaa
     5461 gtagccgcaa attatatcag cattcaacaa tttttgtata caagttctag taaaaggatc
     5521 tgaagaaaaa gttggttgtt gtgaagataa aaaaagaatc aggttttact gagtttttct
     5581 tcaaaatttg tgttattagg ttaggacaaa gataagaaga agtatgaaga tttaaaaaag
     5641 gaatgaggaa aagatagtaa tttccgatta ttggagtttt ttt
//
LOCUS       DBBGRF010000100         5646 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000100 DBBGRF010000000
VERSION     DBBGRF010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.101"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(90..308)
                     /locus_tag="ACIZD4_002829"
                     /pseudo
     CDS             complement(90..308)
                     /locus_tag="ACIZD4_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            549..731
                     /locus_tag="ACIZD4_002830"
     CDS             549..731
                     /locus_tag="ACIZD4_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991678.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            715..900
                     /gene="tnpB"
                     /locus_tag="ACIZD4_002831"
     CDS             715..900
                     /gene="tnpB"
                     /locus_tag="ACIZD4_002831"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGC5991679.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            1143..2663
                     /locus_tag="ACIZD4_002832"
     CDS             1143..2663
                     /locus_tag="ACIZD4_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HGC5991680.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(2850..3422)
                     /gene="hxlB"
                     /locus_tag="ACIZD4_002833"
     CDS             complement(2850..3422)
                     /gene="hxlB"
                     /locus_tag="ACIZD4_002833"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HGC5991681.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(3429..4091)
                     /gene="rpe"
                     /locus_tag="ACIZD4_002834"
     CDS             complement(3429..4091)
                     /gene="rpe"
                     /locus_tag="ACIZD4_002834"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGC5991682.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(4107..4622)
                     /locus_tag="ACIZD4_002835"
     CDS             complement(4107..4622)
                     /locus_tag="ACIZD4_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HGC5991683.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(4624..4908)
                     /locus_tag="ACIZD4_002836"
     CDS             complement(4624..4908)
                     /locus_tag="ACIZD4_002836"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGC5991684.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(4942..>5646)
                     /locus_tag="ACIZD4_002837"
     CDS             complement(4942..>5646)
                     /locus_tag="ACIZD4_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HGC5991685.1"
                     /translation="IDADAETLTKRFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLG
                     IMTAAVMKIMPKMVAMFMEGLMPIAEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMS
                     TSLLLVPISLLLALILPGNKVLPFGDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVT
                     TLYMATWLAPIITDVFTLASFDVGTAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLG
                     VVLVGASIYMNKVKKA"
BASE COUNT         1819 a         1053 c          964 g         1810 t
ORIGIN      
        1 aactaaatga tttcatcatt attttgacac ttttagttgg gagcgtcaat aattttgtgt
       61 caatggttct tccctactgt agattgtttc taattctcca tcggttgact cagcatttgt
      121 tcgagctcgc cttcggcctg ttggaaacct ttatgactgc gacctaggaa tttttggttg
      181 taagtatcaa aagacgagac taagaaacgt tccatcgact cttcattttg gaactgttcc
      241 ttgcggtggc tgtatttctt gatttgttta ttgaaagatt cgattaaatt agttgagtaa
      301 atgcttcgta cgaacatagt tgatttattc accatacttc ccattacatc gtaaaacgct
      361 atatttaaga tttcaaacaa ctatattaat aggaagaaaa cttcattttt cctcttagtt
      421 ctataaaaag tgtggctaat ttgaggcaaa atattaaatt aaatgtaagc gtgtcatagg
      481 atagtatctc gtacgccgat tatctttctt ctataattaa actatcaaat atagaaggag
      541 aaaaacgaat gaataaaaaa gatattgtac cagttcaatt ttcaagtgcg gctcaaaaat
      601 cgcaaattga caccaagcca aaactagctt gcagaatcaa atcggaagat aaggaaatat
      661 ttatttataa tggaatggat aaatatcttt tgtatacctt gttaaaagag ttgaatgcca
      721 atgctcattg atgcaactgc attgaaacat atttttatcg tttgtggaaa aacagatctt
      781 cgaaaaggaa ttgatggact agcagctttc gttatagaag aatatgacct tgatgtttac
      841 gatcaagcgc ttttcttatt ttgcggtacg aagaaagatc gcttcaaggc tctttactag
      901 gatcaaaatg gatttgtatt aatgtacaaa agatttgaaa gtgggtacct tcaatggccg
      961 cgttccagaa aagaagtctt actgactggc ctttcaatcg aagaaaaatg tacgctaaaa
     1021 gaaacgaaaa aaggtgcgat atattagacg aaaaccttgt taaatcaagg attttgtctg
     1081 tttttcgttg tcataaaatg gtataataga tgtaagaaaa tcgctagaat ggtggtgtaa
     1141 aaatgacaaa aatggaatct gaacttcttg tacaaatcaa gcaattaaca cagttgcttg
     1201 aaatccagca acaggaaaat actcttctta gagaacaaat tgctgaaatg aatcgacgct
     1261 tgtttggacg aaaaaaagaa acaccacccg tagatgggca aatcgattta ttagacgact
     1321 caacttttaa tgaaccagag cacactggac aagaaagcca ggaacccatt acggtatctt
     1381 cttttaaacg cagaaaacgc aagggactca aagcactttc attagaaggt ctgcctgaag
     1441 ttcctattca ttatgaatta aaaggtgccg attgtttgtg tgaagactgt ggtcatactt
     1501 tacatgatat cggtgcgaca aggcttagag aagagccatt gtatgttcct gcccatatag
     1561 aaaaacaagt catctaccaa catgcctatc attgcagaga atgtgaagca ttaggagaaa
     1621 caaaaatcaa aaaagcgcct gttcctaaac cgttgatcaa taatagtcta ggttcctctt
     1681 caattgtgac acagagtatt tgggaaaaat ttgttaaaaa ggtgccggca tatcgacaag
     1741 aaaaagaatg gcatgcactt ggtttccctc ttgatcgtaa aaaaatcact aattggcata
     1801 tcaaggtaag tgaaatggtt ttagagccaa tctacaattg ccttcatcaa gaattaagca
     1861 atcaggaggt cttacacgcg gatgagacaa gctatcgggt attgaatact cataaagaaa
     1921 agacctttta ctggttatat gcttcaggta aaagcgaaga aaaacaagtt gtgctctacg
     1981 agcacgcaaa ttcgcgttcc gttgatgagc caaaaagttt tttagaatca tttagcggtt
     2041 tcttgcatac tgatggttac gcggcctatg gaaagctgcc ggtaaacaat gtttattgtt
     2101 gggcgcatgt tcgcagaaag ttttttgaag cattgggtaa acaaccgtcc ccaaaaagtc
     2161 atgccaaaat aggattagac ttctgtgaca agatgtttcg aatcgaacgg acctttaata
     2221 agcttagcgc agaagaaagg tttgtagcga ggaaggaaac gttgcagcct gtgatgactg
     2281 aattttttca ttggtgtgag agttttgctt atttgccaaa atcgcagctt ggaaaggcgg
     2341 ttcaatacgc agtcaatcat aaagacggac ttcagattgt gttgcttgat ggacgcttgg
     2401 aactttcaaa taaccgagca gagcgtgcca tcaaagagtt agtgatcggt cgaaaaaact
     2461 ggctattttc taaaagctta aaaggcgcta gatcaaatgg aattatattg agtattatcc
     2521 agacagctgt tgcgaatggg ttaaacatcc gcaaatattt aaatcatctt tttacagaga
     2581 ttcccaatct gtcttcgatg acacctgaag cgctacgcgc ttatttgcca tggaatcagc
     2641 agatacaaga aatctgtaaa taatataagc cacaaataac ctgatttgag tgtatcaaat
     2701 cgggctattt gtgtttaggt accattctat gacacgctta cgctcaaaac tactgaatta
     2761 ttaagttatg tctaatcaaa taaaaaaacc attctcatat ttgctgaata attagcattt
     2821 agagaatggt tttttatctt taaaatctac tactcaaaat ctgcatgtcg agcaaacatc
     2881 gtttctgagc tttcacctgt tttatccatt aaagataaca ctaaactatc aaaggtgaga
     2941 aatgctaatt gttcaaaact tgaacccata ggttgtgaaa aagtatcttc ttctcgttga
     3001 ttttcatctt tggtaatacc tggtaataca agaacagaat ctgctaattg accaatcgac
     3061 gagtcttttt tcatggtaac taaagcaatg cttacaccac tttgatttgc tttggccgct
     3121 aaatttttta aactacctgt ttcacctgag ccagaacaga taattaataa atctccaggt
     3181 tgcgaatgtg gtgaactaat ttcaccgaca aggctgactg aaaaacctaa atgcattaag
     3241 cgattcgtaa atgcttgcat ggcaattcca gagcgtcctg caccagctag aaagatgtgt
     3301 ttagcttgaa caattttctc actaaattgt tctaactcta cagaattaat acgttttgag
     3361 ttattttgta attctaagat aatcgcttct aaatagtttt tattttggtc tttattggtc
     3421 atgatctttt acttcacttc ctctaatgat tgatttagtt tatcaatttg ttcttgcggg
     3481 gtatttttcc cattgaagat gaaaccgcct gatacaaaaa tatccgcccc tgctttagaa
     3541 caaactttaa tcgtttgatt atcaatcttg ccatctactt caatatcata cgtataatca
     3601 ttttgtttgc gtattacatc taactgttcg attttaacta ctgtctcttg aataaaatgc
     3661 ttattctctg ttcctggatt gattgtcatt actaatactt gatcgactaa agataatact
     3721 ggttcaataa aactgactgg tgttgcagga ttaaaagtaa tccctacttt tgctcctgct
     3781 tccttgacta actgaatgac cttcattgcg tgtttggtag cttcaatgtg gaaggtaaca
     3841 atatctgctc ctgcttctac aaatcttgtg acaatttttt ctggtgtatc aatcatcaaa
     3901 tgaacatcaa acacaacgtc tgttagtgga cgaatatctt taataacact tggtccaaaa
     3961 gccatatctg gtacaaaaca gccatccatt acatcaatat gcaaataatc aacattcttt
     4021 tcttttaaga tttcaaataa ctctttaact tctgcgatag gtgcatttaa caatgatgga
     4081 gcaattgtca ttctctattc ccccgtttat tctcccataa tcatgagatt gattgttcta
     4141 gttcgctctc ttagttgatc ccaatcgaca aaatagacac ggcccatttc tcctaataaa
     4201 agtttacctt cttgaacaat taaagtcatt gagttggttc cataaataga tgaacgtaaa
     4261 tgtgcatcgg tatttagcat gacccatttt tctgcagggt aattgggatc agataatctt
     4321 gttccaaaat caatgtgttt tggccccgga ctgttgtatt gattttcact cgtcattttt
     4381 ggaataatcg tttccattac attgttgatg tctacatgta aataatcatc accaaaaaag
     4441 tttgtgtcat gcatcgtttc ttcaaaaaag agtgagcaag ttgtatgcgg gctcgaaatt
     4501 actaacattc cattctcaat acctgctgta tcaactgtat ctaaaagttc ttttcgaata
     4561 tcatgatacg aaggacgccc tgaaactgtt tcaatagtca aagtgtcatg atgaaaacgc
     4621 atattaaaca cctaatcttt cttttacatc tgcataaatg gcatctgtac caatacctgt
     4681 taataagccc aagccattcg ttactttagc tttaattaca tcagggacaa ttgttgtact
     4741 tactacagca tcatattcat caattttatt tagctcatca gcaattttag attgataaat
     4801 tttcacttga tctgttaatc cttcttcttc caaccatttt gataattttg ctactgcaat
     4861 tgtagaagta gcatgacctg ctccacaaat aactaataat tttttcatat tgatctcttc
     4921 tttcttattt taattttatg attaagcttt cttcactttg ttcatgtaga tagaagcacc
     4981 tactaaaaca actcctaatc cacctattcc aattacacca aagtaagatg ctaataaaac
     5041 aaacaaccct actggccata atccacataa caacatagtt actaatcctg ctgtccccac
     5101 atcgaaactt gctaatgtaa acacatcagt gataattggt gccaaccatg ttgccatata
     5161 taatgttgta acaacataca acgaacatcc tactaatgat ctcacaatat ttcctttaaa
     5221 ataaggaatc attaaacaga tggcgaaagc aaagaatgct aaatctccaa aaggtaatac
     5281 tttatttcct ggaagaatta gtgctagcaa taatgagatt ggtacaagca atagagaagt
     5341 tgacataata gttggatgac ccacagttaa cgctgcatcc attccaatgt ttacttggcg
     5401 accatttaac tttttattcg taaattcttt cgccgcttct gcaattggca ttaaaccttc
     5461 cataaacatt gctaccattt taggcataat cttcatcact gccgcagtca taattcctaa
     5521 gtttccaatt cctgctacgt catagcctgc cataataccc actacaatac cgataattag
     5581 gccaataaca actgtgtcac ctaaaacacc gaaacgtttt gttaatgttt ctgcatctgc
     5641 atctat
//
LOCUS       DBBGRF010000101         5479 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000101 DBBGRF010000000
VERSION     DBBGRF010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.102"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(43..409)
                     /gene="ssrA"
                     /locus_tag="ACIZD4_002838"
     tmRNA           complement(43..409)
                     /gene="ssrA"
                     /locus_tag="ACIZD4_002838"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(580..1353)
                     /locus_tag="ACIZD4_002839"
     CDS             complement(580..1353)
                     /locus_tag="ACIZD4_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGC5991686.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1497..1847
                     /locus_tag="ACIZD4_002840"
     CDS             1497..1847
                     /locus_tag="ACIZD4_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HGC5991687.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1828..2544
                     /locus_tag="ACIZD4_002841"
     CDS             1828..2544
                     /locus_tag="ACIZD4_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HGC5991688.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2544..3992
                     /locus_tag="ACIZD4_002842"
     CDS             2544..3992
                     /locus_tag="ACIZD4_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5991689.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4062..4571)
                     /locus_tag="ACIZD4_002843"
     CDS             complement(4062..4571)
                     /locus_tag="ACIZD4_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991690.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4561..5285)
                     /locus_tag="ACIZD4_002844"
                     /pseudo
     CDS             complement(4561..5285)
                     /locus_tag="ACIZD4_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1863 a          955 c         1095 g         1566 t
ORIGIN      
        1 aaataaggat ttaagcatct agcgaaatct gctgaaatct cacaatggag acggcgggag
       61 tcgaacccgc gtccaaacac atcgccactt aaaaatctac gttcatagtc aactcattta
      121 aggattcact ttacagcttg ccgagtgaca ggcattctgt atcgctagtc tgatgttctc
      181 tttttcaact tacagacgga aagttgaaac gtatcccact aaagttagga cccttactcg
      241 agcacatggg cgatgccgag aggatctacg ctaactgttt ttaggcagct aaagcgtaag
      301 agttgttttc gtttttagca gttatattta actgtaacgt ttttacgtag acgtaaccta
      361 cgaaacgcaa ttcaagctcg actgtgcctg tcgaatccgt aacgtccccg ttagctaaca
      421 agggttacgt gtatttttca tacaaaatta gtatagcata tattgggata aattcaataa
      481 aaaagcgaat catatcccat tatttatata ataactgccc ctttcttaag aaaaaataag
      541 cgattttctt aagaaaagag gtagcttcaa aaaaagatct taaatcagat caaaatactt
      601 caatgcgtgg acaattccgc cttctgtatt tttctttgtg ataaaggtag aaagttcttt
      661 taatccgtca taggcgttgc ccatagcgat tttgttgtcg caagcttcca acaaggcaaa
      721 atcattcgga ccatcgccaa atccaaaagt aggaactttt tccagctgaa gttctttttg
      781 cagacgtttg acacctgccc cttttgagat tcctttcttc actgtatcga tcgagtaagg
      841 accattccga taaaaagtta gctcaggaaa atgttcgtga tagtattcgt cacctgattg
      901 agataagatc agcaacatat ttactgtgtt ttctttaaag cctaaaggat caatttccgg
      961 aacatctgaa tgaatgaagt cgtaagcatt gatcattgtt tggctatgac cggtacacca
     1021 gattttctga tcgttatagt aagaaagttc atgaccgttc aactgtacat gatcatacat
     1081 tttttgacat tcttctgaag aaaatgtttg agaatagatt tcttcgccgt ctactcgaat
     1141 gaaagaacca ttcatggtga ccgcagaagt aatgcccgca tcttccatga tagagtggat
     1201 ttctgcttct gtacgtcctg tagcgatgac ggggagaaca ttgttttctt ttaatgcgtt
     1261 catagctttt gccacttcgg gtgtgatttt tgatttcgca tctagtaatg ttccatcaag
     1321 atcaaagaaa gtgattgcac gataatttga cacaaataaa actccttttt tattggaata
     1381 agtttatctt aacaaagaat gaacaaaaga caaacctttc gtgaagaatt cctgaacata
     1441 ttggttcagt caacaattta gagtatacta taagaagaga atttaggagg gaaagaatga
     1501 tttttttcag tattggtatc ttattcttaa taattggcag tctttttcgg attctgccct
     1561 caaaaggaaa tctgcctttt tatgggtatc attcgcctct tgccgcaaaa acagacgctc
     1621 attggcggct ggctcaaaag acaagcggaa actggttttt tcttatgggc ttactgatgg
     1681 cattgatcgg ctattattta aagacatctg ggcatacgaa ttattttctg attgaaatgc
     1741 ttctgctagt atttccaatt atgcctattt ttattatgac agaaaagaaa ttacagaaat
     1801 atgacctgga aactggaggg aacgataatg aatattttaa tgattgaaga taatcaatct
     1861 gtttctgaaa tgatgcagat gtttttctta aatgaaggtt gggaagcaac tttcaagtat
     1921 gatggaaaag aagggctcga tgccttttta gaaaacccac aacattggga tatgattaca
     1981 ctagacctga atttgcccac actggacggt atgctagtag gaagagagat ccgcaaagtt
     2041 tcaagtactg tgccgattat catgctgaca gctagagatt ctgaaagcga tcaggtgatc
     2101 ggcttagaga tgggggcaga tgattatgtc acaaaacctt tcagtcctct gacgcttatt
     2161 gctcgaatga aagctttgca tcgccgtagt gagttggcag aagcaagaga agaagcagta
     2221 gtttcagatg atcattttga tatcgagact agtcatttca agatgaatac gaaaacacga
     2281 gaagcgtatc tggacaaccg gccaattgaa ggactgacgc ctaaagagtt cgatctattg
     2341 tttactttag caaaaaaacc acgtcaagta ttctctcggg agcagttgct tgaattagtc
     2401 tgggattatc agtactttgg tgatgaacgg acagtggacg cccatatcaa gaaattacga
     2461 caaaaaatcg aaaaggtcgg accacaagtc atccaaactg tttggggagt cggctacaaa
     2521 ttcgatgatt ctggtgttgc ctaatgcgtt atttgtatca gcaactctta gctttctgcg
     2581 gaatggtcgc gttgatctta ttgatcgttg gagtttcttt tacacaactg acaaaacaaa
     2641 cgattgaaga aaacaattac cagcaactgt ttggatatgc tgaatcagtt gaaaagacaa
     2701 cgcaaaccta tgccgatacg ctcccgcagt ttagtcaaga tcaggcgttt caaaatgcat
     2761 tgctgctgac agagcaagta ctgacagaac aaaatgtgaa ctttatattt atcgataaaa
     2821 acgaacgtgt catttatccg actaatacag ctttactgaa ttttacctta acagctgatc
     2881 aatggaaaaa tctgaggaat ggacgtcaag aaaaattcac atcgaataaa aatattttag
     2941 gacaagcaca ggcgacctct tacgcacttg tgccatttaa tttgaatcat gaattctatg
     3001 gagcacttgt agttagtcaa cctgcgcgaa atatcgataa cagcgttcgt ccaattacac
     3061 tgaacctgtt caaaggattt attttttcca gtatcgttgc agttattgcc agctatgctt
     3121 ttgcagcatt ccaagttaag cgtatcaatc ggttaaggaa tgcgacgaaa gaagtgacga
     3181 atggtaattt tgatgtacag ctccccgtac atgacaaaga tgaatttgat gagttagcag
     3241 atgatttcaa taaaatgacg aattcattga aagaatctca agcagaaatt gaagaacaag
     3301 aaaatcgtcg aagacaattt atggcagatg cttctcacga gatgagaaca cctcttacga
     3361 caatcaacgg acttctggaa gggttagaat acaatgcaat ccctgaaaat cagcgagaaa
     3421 acgcgattaa attgatgaaa aatgaaacag agcgtctgat ccgtttggtg aatgaaaact
     3481 tggattatga aaaaatccgt acgaatcaaa tcagtatggt cattaaaaaa ttcaatggaa
     3541 cagaaacatt gaaaaatatt gttgcacagt tagaagctaa agcagaagca gcaggagata
     3601 cattgacatt gaaagccgtt gatgatattg atgtttacgc tgattatgac cgatttgtcc
     3661 aaatcatggt caatattatt caaaacgcga tacagtttac tgaaaacggc caaatcacga
     3721 ttactttaga aaaaggctat cttgaaacga tcatcacgat tgaagatacg ggaattggaa
     3781 tgtctgaaca acaaatgaaa agtatctggg atcgttatta taaagtagat ccttcaagaa
     3841 aaaatacaaa atatggtgaa tcaggattag gtttaccaat cgtgcagcaa cttgtacgct
     3901 tgcataaagg aaaattagaa gtagaaagcg aactaggaaa aggaacaaaa ttcgctgttc
     3961 gtttgcctga cgtagaaatc aaaaaagagt aaaaaacaag cggtataaaa gatcatgaat
     4021 cgatcttcta taccgcttgt ttttactata aaatgattga tttagcccgc gggctctaaa
     4081 cgatcaatat aaggactttg agcaatagta gcatcatgag taaagagtaa gataccttga
     4141 ttttcttcat gagctaaata agaaagcaag tggagtagct cttggatctc caatacacta
     4201 agttcatcaa atgtatcttc aataacaata ttgtttcgct tggaaagcaa ggcatgaagt
     4261 aattgcagct ttactttttc aaaagacgtc aactcagctg ccgcacaatt aagcaaggaa
     4321 ggagagatat caagtttttc ttgataggcc aaacgatctt gtttgatttc tttttccggt
     4381 acatccaaca ggacatggtc tttaagattc agataaggaa acatcggcca atttttttgg
     4441 atgatcgcaa aattatccag ttttgcaaca agaacctctt ttttcaagtg ctccaatatt
     4501 ttatgctgtt tttcgagagg acacaaaata acggtcaagt gttcagcatg aatcaaatat
     4561 tcaggtttca ttacgtccag gcctcctact ttgcaaatga tggataaaaa agtgaaaggg
     4621 aatagactaa gaatgagaca gcatccactg agcccaataa gagtttgggc aaatccctta
     4681 agtatatctg tgaaaaaaag atcattttgg aaatcgatgg taaaaaaagt ctgttgatcc
     4741 atcggaattg taagtccgct taccgaagtc aagatatcac ggatatctgg cagttcagta
     4801 gtctttaaga caagaaaatt gatcctttga agaagcgctt cataaactga ctggaagctt
     4861 acgatccaca ataaaaccaa gatacaacaa agaaagagag gaaagaacag ctgccagaaa
     4921 ataaaaagga ataatttggt tttagaaaga ccagtcaggt gccaattgat caattcctgc
     4981 ttgttttgcc tgactgaata gtaaaagaaa aagataaaaa ggaaggcaaa tagaaaaaat
     5041 aaactgaata tgccttttat ataaaatcgg ctagctaatt ctaaagccgg aagaagctct
     5101 gtagatgcag aagcgccaat aaatgaaagc cgatcttgga cttgattggc taaagccgat
     5161 tgcaaatggt aaagagtcag gcatgctatc aataaaaaag cagaaaagct tgaaaataaa
     5221 caatagagta ttgtctgctt tttgtaataa attaatcgag cagtagcata gcggattatt
     5281 ttcatacttt tcacctctat aaaaagtata gaaaatgaat atgaataaag tatgaaattc
     5341 ctttagtgaa atcacgaatt aaaaccagaa aatattttgt aaaaagcaag aggttgtgaa
     5401 gaagctgccc tattctatta ccgtagatgc aagcttttga acactgttta ttcgaaaaga
     5461 ggagcagcga caataattt
//
LOCUS       DBBGRF010000102         5340 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000102 DBBGRF010000000
VERSION     DBBGRF010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.103"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(61..285)
                     /locus_tag="ACIZD4_002845"
                     /pseudo
     CDS             complement(61..285)
                     /locus_tag="ACIZD4_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(839..925)
                     /locus_tag="ACIZD4_002846"
                     /pseudo
     CDS             complement(839..925)
                     /locus_tag="ACIZD4_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2091..3131
                     /locus_tag="ACIZD4_002847"
     CDS             2091..3131
                     /locus_tag="ACIZD4_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGC5991691.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3955..4287
                     /gene="traE"
                     /locus_tag="ACIZD4_002848"
     CDS             3955..4287
                     /gene="traE"
                     /locus_tag="ACIZD4_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HGC5991692.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4906..5247
                     /locus_tag="ACIZD4_002849"
     CDS             4906..5247
                     /locus_tag="ACIZD4_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HGC5991693.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1769 t
ORIGIN      
        1 aggtattttt attatatata gatttaacat atgtcggtcg gttgattgat atagctaaag
       61 ttataactca accgaagccg attcatctac acgaataaag ttgcgagtgt tctcggctaa
      121 ttcataaaaa ttgttatgtg ttccatatag caatactgga ataactttat tttcttgaat
      181 ctcataagca actctataca cggtgaccgc atacttaaat ccattagacc aattacctga
      241 taaacctcca gttttttgct cttacttaaa tggatcaatg gcaatttcat cacaaaccta
      301 tagaggatga gtgacttctg cctaattacg ttaaaaaata ttgaaagtaa ctctatgtag
      361 caaaaaatat ctagaatttc atttcctcaa aactgatcga tattgtatct aaaaatatat
      421 actacctaaa ataggtagta tatattaaaa tatgtgcttt tgttagaaaa atcaatacat
      481 aaattatcat atctgtatat gtcatttagg tatttcagtt atgttataat agttttgctg
      541 tctgctaccc cggcctaatc tggcaagggg aggaggagat ataatgaaat acctttttga
      601 ttttgttttt gcaatcaagc cacttgcaga tgtagtgtgc agttacctct gcaaatggct
      661 tgattgcaaa attgccaaaa aagacagtaa gcctacccgt taattctata atatagaaac
      721 gtaaaaaaaa ccccatcagc ctgcacgctg atggggtttg gtgatataat gaaatacctc
      781 tttgttactc ataattatac cataattagt cacgaatgca accaatagaa aaaactactt
      841 agaacggtag atcatcgcta ataacaatgc attgtccacc aaatggattt tgtgaagcat
      901 taaatacatt gttattaatt gtcgctgctt ttaactaggc ctctcccctt ctattataaa
      961 agaagatata tatcatttct taattaccta ctaccttaaa ccaaaattta agtactacct
     1021 aatttaagta gtacttaaac aatctaaaaa atagttatcc caattgttat gcttttataa
     1081 tacgattatt tgtaacaaaa tgaatattat ataattaaac actaccatat ttaggtagtg
     1141 tttaattatt agcaaaacaa aaaatattta ttctattctc ttaacttcaa ctaagttatg
     1201 ctgcacacct ttatataaat catatgcaac tcattagcta gacaaactac aagcatgtag
     1261 ttttatctgt taattatgta ctacctaaat aaagtagttt ataattagca agtatatata
     1321 tttaaaaatt taagattaat ttttttatga cttgtacaaa tttatctgat attctcttat
     1381 taagaactac ctaatttggg tagttcttat tttttacatt ttaagtagta tttaattgca
     1441 atttggtagt atttttttat tatcttattc ttagaacggt agtacttaat ataaatatag
     1501 gtagtatcta atttaagtat taatggtagt atctaaatta acaggtagta tgtaactact
     1561 ttaaagtaat ttttttcaga ttaacacagt agtatcttat taaataagtt aattttaatg
     1621 gtagtacata attattatat atatctgaca ttggtagtac ttattgtatt ttttagtagt
     1681 atataatcta ttgttttcta gcctaaagcc ttgtcttata agaataatat aatatatact
     1741 actgaaataa ggtagtatat attactagta atggtagtat gttttatatg cataaggtag
     1801 ttcttaattt attttttgtt ttgacactgg tagtacttaa ttatctttaa ttttaaaact
     1861 aaattttatt catacgtttt tctggtagta tttaattata aataatattt atttaaagta
     1921 gttcttaatg actttaaagg tagtacataa ttcattttat ttctgatttt aggtagtatt
     1981 taattaaaaa acagttttaa tgcgtttgca ttttttattt atctttgcta ttttcgaaaa
     2041 gagtaggtaa ttttacataa ataaaacaac gtgaaagtag aggatctaca atgactgatt
     2101 ttaaattttt taaggcggat agagtttaca acgaattatt ttatcaattt ccaaaagtct
     2161 ttattgtttc tgacgaatac aaaaaaatga aagattcaac taagattgcc tatatgcttt
     2221 taaaagcaag attagagatc gcaatcagca aacggcaaat cgatgaagaa ggtaatgttt
     2281 attttactta tacgacaaat gaactatgta gagtattaaa ctgccaaaaa caaaaagcga
     2341 tagcaatcaa aaaagagttg gaatcctttg gtttattatt acaaaagcag atgggattta
     2401 acaaacagtt agggaaaaat aatcctaata gactatatct agcagaatta aaagtctcag
     2461 aaaatgatat ctacttactc gaaaaatttg atagagagaa tagggaaaac gttgataaat
     2521 cagagggtat gaaaatcata cccaccctcg acgaaaaatc agacgctgaa tcccttgggg
     2581 ctcaagaggg tatgaaaatc ataccgtgcc aaaacgttga taaatcagag ggtatgaaaa
     2641 tcataccaga acttaataat aatatattag acactaatag acacaatata gacactgaaa
     2701 aagaccgcct acaagatcaa ttgttgttag acaattttga gacaattatg acaaacgaca
     2761 gcattgctac gtttgtccct gaacgagtat taaatttgat aaaaacattt tcttcaagtt
     2821 acagtgaagc tcaaaaaacc gtccagacta ttcataatgc aaagaaaaaa gctgaaatag
     2881 aaagtgatat ttcgatagtt tttgaagaac tcgatagtta ttatgtcaat gcagaacaag
     2941 aattatacac gacactgtta aaagcctatc aaaaattaaa aaccgaaaaa gtcgaaaata
     3001 tccagaacct gatttttgtc tatgtaaaaa attggtttat cgaaaaacca atagctgcta
     3061 aagtatcaag tgaaaaacgt ttgaattatg caagctcccc aagcactatt acgaaagact
     3121 ggttagagtg aaactttact gacaaagtga ttgttgcttc atggagtaac attaaaatta
     3181 aaaatttttt attattctaa ttatattacg aatattacaa aataatagct attttaatag
     3241 aatttataag ttaaaatatt atgataaaaa tcacaaacgt agccttttac gtcataagtg
     3301 ttaaaagaaa taattaattt caaatataga aaagggaacg tatgtttgca tactcctttt
     3361 ttttgagtta taataatacg cgaagagaga taatttcatt atttaaacaa gctaaaaatc
     3421 ttgatattac ttcttttcag gcaatacgaa tattattcgc ttacattttt tgtataaatt
     3481 taattgtctg ctatgcttgt gatgaattga ttttcgtttt gcacttttgg atgataaatt
     3541 tggacaattg aaaatacaaa aaaaagaaag gcggtatgaa ctcggaaggc tggtaacctt
     3601 cgtcagcgtt catacacggc attaagattt ggcccttaat gcgttaacct ttcagtgtta
     3661 cggtattacc cgcaatggat ttagtataac agatattcaa aagtgatacc actttttttg
     3721 gctgtgttaa ggttaaaaat acgtgatatt acgatgaatc tatgcctaag cataatgtta
     3781 taaaaatgtc cgtgtggctc tttgccgtat gacgaacgct gaaattagag ggaacgcatg
     3841 tttggatgcg ttccctcttt tttgtttgtc atgaacgaaa atcaattctc tatttttgaa
     3901 aaataacaag aaaaacttgt taaaaatatt taaagaaatt gggtggttta ttttatgtca
     3961 tatacaggaa ttttgagtct caaagatatt tgtcactacg gtaaacggtg taccgctaca
     4021 gagaaaatca cgaagaaact atcaactggc caaagtaaaa ccgttgtgca gtgtaagaaa
     4081 tatataatcc agaaagacaa agtctcagag gaaatgattt attacattgg gaaacaaaag
     4141 caaataattt taaaagatcc tatcccctta aaagagctat atccaacaat caaacatgtt
     4201 tatgaccaaa acggtgtact gattggtcga agaaaaaatg gagtcttgcg ttgtaccgca
     4261 aaagggatgg ggcgtttgat cggctgaatt gatcattctc ataacttgta ttttatcgtt
     4321 tttcgcttgc ttgaaaatat tgtcgagact tctaaaggaa cttagagtca ctagaaaaat
     4381 aaggagtaga cttgatctat caacaattcc cttcggggag tgacggggta ggttttaacg
     4441 attggtaacg taaaaaattg gtcaatcgag taaatgcgct tgtttggata gtggtgaaat
     4501 gaatttgtgt aaataataag cgcagagtaa acaagaggga atttagaagt tagacaagtt
     4561 agaatagcgt ctagattaat catgagcagc tactaaggga tctagacttt gacgcaaact
     4621 catggaataa ggagtaggtc ttctcgtaat ggggaggacg cacaagaaat tgtgtcgtgt
     4681 gctgcagtac atgtagatac ttgcgaggac gttgattatt ggatcaatcg agcatttacc
     4741 gctgtctact agggtttctc gtttcggacg ccataaacga gtcgaaattt tttatgtatt
     4801 tttaagtaaa cgaaaaacga taaaatatga acaagtcctg aataaagtga aaaaattaat
     4861 ataaagcata gagaaaatga aatttacgta atggaggaat gacaaatgaa aaattatgat
     4921 ccgaatatac gattgggcac acatactatt aaggtttctt tccaacgttg ggattacaaa
     4981 ggatttgtga cgtttagaag gggcggaaat tgtaaaggat tagatgtttt agcattagac
     5041 gaggatgatt tatacgatca aacattgact gataatccaa ttggattcgg cttgctacct
     5101 gaagatgatg aaggtaatga atggtttaaa atgacgctta tgaatgataa tggagacgaa
     5161 ttatctgttg aagatacttg gtcatatttg agtgattata ttgtcagctt tgaaatcatt
     5221 gaatttgtag cggataaaga agaataaaaa ctggaggaat aaattttaca gataaaggct
     5281 tagaaggagt cacgacgatt aataaaaagg tagtattacc ttaggcattg agtaaggaat
//
LOCUS       DBBGRF010000103         4945 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000103 DBBGRF010000000
VERSION     DBBGRF010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.104"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            132..2705
                     /locus_tag="ACIZD4_002850"
     CDS             132..2705
                     /locus_tag="ACIZD4_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HGC5991694.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIPE
                     K"
     gene            complement(2778..4325)
                     /locus_tag="ACIZD4_002851"
     CDS             complement(2778..4325)
                     /locus_tag="ACIZD4_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HGC5991695.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(4427..4780)
                     /gene="tnpB"
                     /locus_tag="ACIZD4_002852"
     CDS             complement(4427..4780)
                     /gene="tnpB"
                     /locus_tag="ACIZD4_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGC5991696.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT         1524 a          954 c         1035 g         1432 t
ORIGIN      
        1 tacaaaaaag aaattttcac ctaacagaaa aatttgccat aaaaatacat attttaaata
       61 tgaaagtaca attacaaata aattaaaacg ttaaaataaa attgtcaaaa cgtcagagag
      121 gatggtggag aatgaatcaa tatgtaaaaa agctgattgc gtcgattttg tttgtcttcc
      181 ctctcttgat ggtgacatcc gtttttgccg atgtagagaa aacaagcgaa tcaacgcaat
      241 cagagaatca aagttttgac aagactactt tttcagaaga atcaattact tctgaaacta
      301 cagaatccca aagtgaggcg cctacttcta atacaaggca agaagaaaat aagacaagtg
      361 agacctcaga agtagctgaa caaacgtctg atagcagtga agaggtacag gttagagttg
      421 tttcagcgga tgggtacagc gaagctgcca caacagaaga actgacgcag cttctcgcag
      481 acgaatcagt agctaagatt cgtttaactc agcctttgac tttagacagg gaattggaga
      541 tcaagcgaga tatcgttatc gattttggcg gacttgctca taatttcggc acacatcaca
      601 tctatatcaa tgagacacct cagtcgatcg agtttcagaa ttttaaagga acggcagctc
      661 atccaggtgg gttgatacca aatatcgatg gaaatgccat tatcattgct tatatgtccg
      721 atttttgggg aaacagatat cattttacgg gagaaataaa atttaccggg acacttgact
      781 tatatgatgg ttctaaatta ggcctgattt acgcccctcg tgcaactgtc acattagatg
      841 gtgtttccgg tgtattggat gtccaaccag tgaaagaagg gatgaatgcc gctccgggta
      901 aagcttattt ttgtagaagc tatcagctaa atgtaatcaa tggtagtcag ctttatggac
      961 catatctagg aaaattctat ggttttctag attcaggtga tgagacgggc agtggaaaaa
     1021 cagcaccagg actccatatc ttgagtggtt caaaggtctc tcttgactat gatcgggcag
     1081 atggcgtcag cgatgaagga gaggctgtcg atacgctacc cgggaatgtc acatttaaag
     1141 tcagtggctc aggaagtgaa ttttcggtaa atacaaagat caatattacc aacgacaaca
     1201 atcgcggaat tatccaaatg agaggctcag gatcaagagt cgctgtgtcg aatgatggga
     1261 aaatcacaat caatacagcg actactggcg gatttcgcct gcaaggagat tctagtcaaa
     1321 tccatgtatc aagtggtgga caaatctcgg tcaaaatggc tggagatggc gaccaacctg
     1381 gaaacaatgg gatgcgtttt gtagggaaag gactttcttt gatcgtagaa ggagccggat
     1441 cagtcatcga tattgataag caaagtggtc gttctagcgc agttcgtttt gagaacggta
     1501 cgcaaaaact aacagtaact aatggaggct cattgaaggt aagaaatgca ggggatggca
     1561 aatcttatgt gaacagactc aatcaaggaa accaagcgat ccaattttat gacgcttctg
     1621 gttttctaga aagtccaggg tcagctgatt ttacggttac tggagaaaaa tcaaatatcg
     1681 atatacgcgc agattccgga gctaccgtag atacaactgg agatattgat ttgaacttta
     1741 tggctggcga aaaaacttat ttagtcatgg tcgggaaaac tggggaagat aagactggca
     1801 tcatcagtgg ggatgtgttg aatgtagact tagaatctcc tacctatttc gatttccaaa
     1861 acaaacggat cggaagcgag actaatggca taggtggctg ggtatttcaa ggaaatggcg
     1921 attcttcttt gaagatcgct cattcagaaa ttgctttatg gcgaaaggca ggagtaacgt
     1981 tcgataactt tgaaaaagat ccggattatt tttctgatat gacagactta tcgatcaatg
     2041 gaaccgactt aggtaatttt gtatcaagcc ctagtgcagg tttaacaaat gaatttgctc
     2101 agacaggtgc cggaatgaaa aattataatc gaatcagtgc caataaccag cttccgatga
     2161 ttgaatcctt aagagtacca acgaatgcag ataaaaaaat ctatgggcat gtcgttgttc
     2221 ccgaaggtgt cgaggcaaag ccaagagatg cttggacagg cgaagtagaa gtgactttac
     2281 gtattactta tgcagatacg acgaaatcac ctgtagaaat tactgctctc acacaaggac
     2341 aaacagatga aaatgaaggg acaggatata atccgtgggg agaaggcgaa caaggcggtt
     2401 tgtttgaggt tcaagtaccc aacgaagaaa gactaacaac gggggatcaa gtgcaaatag
     2461 ttgctgctaa aaaagtaaga ggcggccaag aagtgacaga actggactct gccaaaacga
     2521 cagtcgatgt gattcctcct gagcctgcta aattaagtac cacattgatc aatgcagctt
     2581 ctcgctcaat cacaggtaca ggcgaagcag gagctttggt ttcattgaaa aaaaatcaag
     2641 ctgttttgtc cgaaacaact attgatgata caggtaaatt tgttctttct atcccagaaa
     2701 agtaagcgcc ccatagaaca gtacctgtac gtcaaataac ccgacctata gaatagaatc
     2761 gggaatgttt ggcgttttta gttacgagaa aaatgttgtt gtacatcctt gttccaaggc
     2821 aacagttgat ctaaagtttc tgctgaaagt acgggaagat ttggtatctt atcaaataga
     2881 aactctagat actttacagg attcaatccg ttaagttctg ctgttttata tacactcaga
     2941 atgattcctg aagttcgtgc tccttcaaga cttgtggaat gcaaccaatt tttccgtcct
     3001 atcaccagct ctttgatatt tcgctccgca cgattatttg tgagttctaa acgaccatct
     3061 tcaaaaatag gttcaaaacc acttcgtagt ttacacgcat attgaacggc tgcatccaac
     3121 ttggattttg caacaggatc tatcgttgcc atccactcat aaaaagcaat aaataatgga
     3181 cgcagttctt gttgccgaca gcttaatcgc ttctcaggag aaaagtcttt ccatttcttt
     3241 tctaggacaa accatttatc caattgtttg actgcttgag ctgcgggaat atccgtgttt
     3301 ttctttcctt ttggaattgc ttcgaaaaat ttccgccgaa catgcgcgaa acaatagaca
     3361 agtcgtacac tttccacggc attatacccg ctatagccgt cacagtgtaa ataccctgta
     3421 aactccttga gaaaagtttt cggaacatct ccagcacgac tttcgtcgtg gtgataataa
     3481 acgatgggat gctgactgtc ttttcctgta caaaactgcc agtaataggt atctgttttg
     3541 gcactttcaa tcacacgata acttgtttca tccccgtgta gaatctcttc ttgattaaga
     3601 tagactctta atcgttctcc taaagggtct aacgcgtttt gcactgcttt aatatgccaa
     3661 ttggtgatat tatctctcga aatatccaac ccatgtgttt gtttccaata gttctcttgc
     3721 cgataggcag gaactttctg accaaatttc atccggatcg tttccgccac taaactattg
     3781 gaacctaagc tattagaaat caaaggttta ggaacgatcg cttttttaaa agaagaaagt
     3841 ccttcttttt cgcagctttt acaacaatag gtatgttgat aatgggtgag acaatccaac
     3901 atagcctgat ggaaacgaat ttcttctcgt acttttgtcc gtccgatatc tttcatctgt
     3961 gaaccgcaat gttcacaaaa ttgttcttcc aaaggaagga gatgttcttt ctctgttata
     4021 ggtaagtgtt tgattttgtc tgctttcgtt cctacaactc gttgatgtcc ttttactgga
     4081 ataatggtgg cagctgcttc tggaacactt acagaaattt cttcatcact aaaaagattc
     4141 aattgcccat tcgtttcctc aaagagagtc tctttagagc gtccaaataa tttgttggtt
     4201 aaataattga ccttttcatt caatagttgg atttcagttg taagattctg aatggtttgt
     4261 tgttgtgctt gattggtttt atgggcttct tgaagcaact gaagcaacgt atctgtagtt
     4321 tccaaaattt ttcaccacct tgaatcgaac tgattttgtt acagaatacc acaagaaacg
     4381 cacaagaaat aggggttcaa cacatttttt gtgttaaccc cccagcttaa aaaactcctt
     4441 tttttcctgg caaaatagct cgaggttgat cgatacttaa tccttctaac aaccatcgaa
     4501 cctgttggtt cgttaaggtt cgaacttcgt ctttcgtccg aggccatttt aacttgccgt
     4561 tttctatccg cttataacag agaagaaaac catcaccgtc ccaatagaga agtttgaaac
     4621 ggtcttgacg gttcccgcaa aataaaaaaa cggcatcttc gtaaagctcg agttgatact
     4681 cttgttgaat aagactggca agaccatcaa ttccttttcg caaatctgtt tttccgcaca
     4741 caatataaat atgtttggtt tgaagtaaat cataaagcat tggacaacag ttctttcaaa
     4801 atagcttgaa gaatataatt gttaataccg ttatagatca aaacttcaga accattctct
     4861 cttttgatgc gcatcgctaa cttggcagcc gcgggtttac ctttttctgg tgcactcttt
     4921 tcgtttccta attggacagg aacaa
//
LOCUS       DBBGRF010000104         4869 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000104 DBBGRF010000000
VERSION     DBBGRF010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4869
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.106"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            49..744
                     /gene="vanR-A"
                     /locus_tag="ACIZD4_002853"
     CDS             49..744
                     /gene="vanR-A"
                     /locus_tag="ACIZD4_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HGC5991697.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            722..1876
                     /locus_tag="ACIZD4_002854"
     CDS             722..1876
                     /locus_tag="ACIZD4_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HGC5991698.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2091..3059
                     /locus_tag="ACIZD4_002855"
     CDS             2091..3059
                     /locus_tag="ACIZD4_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HGC5991699.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3052..4083
                     /gene="vanA"
                     /locus_tag="ACIZD4_002856"
     CDS             3052..4083
                     /gene="vanA"
                     /locus_tag="ACIZD4_002856"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HGC5991700.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4089..4697
                     /locus_tag="ACIZD4_002857"
     CDS             4089..4697
                     /locus_tag="ACIZD4_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HGC5991701.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(4777..>4869)
                     /locus_tag="ACIZD4_002858"
     CDS             complement(4777..>4869)
                     /locus_tag="ACIZD4_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HGC5991702.1"
                     /translation="RGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT         1500 a          936 c         1135 g         1298 t
ORIGIN      
        1 taatctgata aattattaag ggcaaactta tgtgaaaggg tgataactat gagcgataaa
       61 atacttattg tggatgatga acatgaaatt gccgatttgg ttgaattata cttaaaaaac
      121 gagaattata cggttttcaa atactatacc gccaaagaag cattggaatg tatagacaag
      181 tctgagattg accttgccat attggacatc atgcttcccg gcacaagcgg ccttactatc
      241 tgtcaaaaaa taagggacaa gcacacctat ccgattatca tgctgaccgg gaaagataca
      301 gaggtagata aaattacagg gttaacaatc ggcgcggatg attatataac gaagcccttt
      361 cgcccactgg agttaattgc tcgggtaaag gcccagttgc gccgatacaa aaaattcagt
      421 ggagtaaagg agcagaacga aaatgttatc gtccactccg gccttgtcat taatgttaac
      481 acccatgagt gttatctgaa cgagaagcag ttatccctta ctcccaccga gttttcaata
      541 ctgcgaatcc tctgtgaaaa caaggggaat gtggttagct ccgagctgct atttcatgag
      601 atatggggcg acgaatattt cagcaagagc aacaacacca tcaccgtgca tatccggcat
      661 ttgcgcgaaa aaatgaacga caccattgat aatccgaaat atataaaaac ggtatggggg
      721 gttggttata aaattgaaaa ataaaaaaaa cgactattcc aaactagaac gaaaacttta
      781 catgtatatc gttgcaattg ttgtggtagc aattgtattc gtgttgtata ttcgttcaat
      841 gatccgaggg aaacttgggg attggatctt aagtattttg gaaaacaaat atgacttaaa
      901 tcacctggac gcgatgaaat tatatcaata ttccatacgg aacaatatag atatctttat
      961 ttatgtggcg attgtcatta gtattcttat tctatgtcgc gtcatgcttt caaaattcgc
     1021 aaaatacttt gacgagataa ataccggcat tgatgtactt attcagaacg aagataaaca
     1081 aattgagctt tctgcggaaa tggatgttat ggaacaaaag ctcaacacat taaaacggac
     1141 tctggaaaag cgagagcagg atgcaaagct ggccgaacaa agaaaaaatg acgttgttat
     1201 gtacttggcg cacgatatta aaacgcccct tacatccatt atcggttatt tgagcctgct
     1261 tgacgaggct ccagacatgc cggtagatca aaaggcaaag tatgtgcata tcacgttgga
     1321 caaagcgtat cgactcgaac agctaatcga cgagtttttt gagattacac ggtataacct
     1381 acaaacgata acgctaacaa aaacgcacat agacctatac tatatgctgg tgcagatgac
     1441 cgatgaattt tatcctcagc tttccgcaca tggaaaacag gcggttattc acgcccccga
     1501 ggatctgacc gtgtccggcg accctgataa actcgcgaga gtctttaaca acattttgaa
     1561 aaacgccgct gcatacagtg aggataacag catcattgac attaccgcgg gcctctccgg
     1621 ggatgtggtg tcaatcgaat tcaagaacac tggaagcatc ccaaaagata agctagctgc
     1681 catatttgaa aagttctata ggctggacaa tgctcgttct tccgatacgg gtggcgcggg
     1741 acttggattg gcgattgcaa aagaaattat tgttcagcat ggagggcaga tttacgcgga
     1801 aagcaatgat aactatacga cgtttagggt agagcttcca gcgatgccag acttggttga
     1861 taaaaggagg tcctaagaga tgtatataat tttttaggaa aatctcaagg ttatctttac
     1921 tttttcttag gaaattaaca atttaatatt aagaaacggc tcgttcttac acggtagact
     1981 taataccgta agaacgagcc gttttcgttc ttcagagaaa gatttgacaa gattaccatt
     2041 ggcatccccg ttttatttgg tgcctttcac agaaagggtt ggtcttaatt atgaataaca
     2101 tcggcattac tgtttatgga tgtgagcagg atgaggcaga tgcattccat gctctttcgc
     2161 ctcgctttgg cgttatggca acgataatta acgccaacgt gtcggaatcc aacgccaaat
     2221 ccgcgccttt caatcaatgt atcagtgtgg gacataaatc agagatttcc gcctctattc
     2281 ttcttgcgct gaagagagcc ggtgtgaaat atatttctac ccgaagcatc ggctgcaatc
     2341 atatagatac aactgctgct aagagaatgg gcatcactgt cgacaatgtg gcgtactcgc
     2401 cggatagcgt tgccgattat actatgatgc taattcttat ggcagtacgc aacgtaaaat
     2461 cgattgtgcg ctctgtggaa aaacatgatt tcaggttgga cagcgaccgt ggcaaggtac
     2521 tcagcgacat gacagttggt gtggtgggaa cgggccagat aggcaaagcg gttattgagc
     2581 ggctgcgagg atttggatgt aaagtgttgg cttatagtcg cagccgaagt atagaggtaa
     2641 actatgtacc gtttgatgag ttgctgcaaa atagcgatat cgttacgctt catgtgccgc
     2701 tcaatacgga tacgcactat attatcagcc acgaacaaat acagagaatg aagcaaggag
     2761 catttcttat caatactggg cgcggtccac ttgtagatac ctatgagttg gttaaagcat
     2821 tagaaaacgg gaaactgggc ggtgccgcat tggatgtatt ggaaggagag gaagagtttt
     2881 tctactctga ttgcacccaa aaaccaattg ataatcaatt tttacttaaa cttcaaagaa
     2941 tgcctaacgt gataatcaca ccgcatacgg cctattatac cgagcaagcg ttgcgtgata
     3001 ccgttgaaaa aaccattaaa aactgtttgg attttgaaag gagacaggag catgaataga
     3061 ataaaagttg caatactgtt tgggggttgc tcagaggagc atgacgtatc ggtaaaatct
     3121 gcaatagaga tagccgctaa cattaataaa gaaaaatacg agccgttata cattggaatt
     3181 acgaaatctg gtgtatggaa aatgtgcgaa aaaccttgcg cggaatggga aaacgacaat
     3241 tgctattcag ctgtactctc gccggataaa aaaatgcacg gattacttgt taaaaagaac
     3301 catgaatatg aaatcaacca tgttgatgta gcattttcag ctttgcatgg caagtcaggt
     3361 gaagatggat ccatacaagg tctgtttgaa ttgtccggta tcccttttgt aggctgcgat
     3421 attcaaagct cagcaatttg tatggacaaa tcgttgacat acatcgttgc gaaaaatgct
     3481 gggatagcta ctcccgcctt ttgggttatt aataaagatg ataggccggt ggcagctacg
     3541 tttacctatc ctgtttttgt taagccggcg cgttcaggct catccttcgg tgtgaaaaaa
     3601 gtcaatagcg cggacgaatt ggactacgca attgaatcgg caagacaata tgacagcaaa
     3661 atcttaattg agcaggctgt ttcgggctgt gaggtcggtt gtgcggtatt gggaaacagt
     3721 gccgcgttag ttgttggcga ggtggaccaa atcaggctgc agtacggaat ctttcgtatt
     3781 catcaggaag tcgagccgga aaaaggctct gaaaacgcag ttataaccgt tcccgcagac
     3841 ctttcagcag aggagcgagg acggatacag gaaacggcaa aaaaaatata taaagcgctc
     3901 ggctgtagag gtctagcccg tgtggatatg tttttacaag ataacggccg cattgtactg
     3961 aacgaagtca atactctgcc cggtttcacg tcatacagtc gttatccccg tatgatggcc
     4021 gctgcaggta ttgcacttcc cgaactgatt gaccgcttga tcgtattagc gttaaagggg
     4081 tgataagcat ggaaatagga tttacttttt tagatgaaat agtacacggt gttcgttggg
     4141 acgctaaata tgccacttgg gataatttca ccggaaaacc ggttgacggt tatgaagtaa
     4201 atcgcattgt agggacatac gagttggctg aatcgctttt gaaggcaaaa gaactggctg
     4261 ctacccaagg gtacggattg cttctatggg acggttaccg tcctaagcgt gctgtaaact
     4321 gttttatgca atgggctgca cagccggaaa ataacctgac aaaggaaagt tattatccca
     4381 atattgaccg aactgagatg atttcaaaag gatacgtggc ttcaaaatca agccatagcc
     4441 gcggcagtgc cattgatctt acgctttatc gattagacac gggtgagctt gtaccaatgg
     4501 ggagccgatt tgattttatg gatgaacgct ctcatcatgc ggcaaatgga atatcatgca
     4561 atgaagcgca aaatcgcaga cgtttgcgct ccatcatgga aaacagtggg tttgaagcat
     4621 atagcctcga atggtggcac tatgtattaa gagacgaacc ataccccaat agctattttg
     4681 atttccccgt taaataaact tttaaccgtt gcacggacaa acggttctgt tgcaaagttt
     4741 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     4801 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     4861 taatcctcg
//
LOCUS       DBBGRF010000105         4742 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000105 DBBGRF010000000
VERSION     DBBGRF010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.108"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(26..1024)
                     /locus_tag="ACIZD4_002859"
     CDS             complement(26..1024)
                     /locus_tag="ACIZD4_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HGC5991703.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1099..1395)
                     /locus_tag="ACIZD4_002860"
     CDS             complement(1099..1395)
                     /locus_tag="ACIZD4_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991704.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1388..1681)
                     /locus_tag="ACIZD4_002861"
     CDS             complement(1388..1681)
                     /locus_tag="ACIZD4_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HGC5991705.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1827..2378)
                     /locus_tag="ACIZD4_002862"
     CDS             complement(1827..2378)
                     /locus_tag="ACIZD4_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HGC5991706.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2552..2851)
                     /locus_tag="ACIZD4_002863"
     CDS             complement(2552..2851)
                     /locus_tag="ACIZD4_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HGC5991707.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2878..3153)
                     /locus_tag="ACIZD4_002864"
                     /pseudo
     CDS             complement(2878..3153)
                     /locus_tag="ACIZD4_002864"
                     /inference="COORDINATES: protein motif:HMM:NF017894.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
     gene            3491..4174
                     /locus_tag="ACIZD4_002865"
     CDS             3491..4174
                     /locus_tag="ACIZD4_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HGC5991708.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4211..4708)
                     /locus_tag="ACIZD4_002866"
     CDS             complement(4211..4708)
                     /locus_tag="ACIZD4_002866"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991709.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1404 a          907 c          694 g         1737 t
ORIGIN      
        1 tttctttgat aaataatatt ttcaattatt taatcatttg aaaattgtta gtcattccaa
       61 tacgttgaga aattcttcca tctgtataaa cacgaaattg ttttccacca gccatggtcg
      121 tgtttccatc atcatccgtt acaatattaa ttgaatagta gcttccattt tcatcttgca
      181 ttagatcttt catatattca tttgtgctaa ttaaattagt atttgataca tttttatcag
      241 gagaatcata caaccataaa gctttattat ttagcacaga ttctttagca gcttcccaac
      301 ttgaaattcc tgaactactt gtagattgtg tcgttgtagt tgttgcttgt tgagtagatt
      361 cttctactac tggtgtttga ggagtttgtc cattcacaat atcactgaaa ccttgtttta
      421 actgttgatt ttgagtttcg ttaaagtaca gataattatt ttcattacct tgattttgtt
      481 gcgttaaata aactttaggt tgtccatttt gaaaaccgaa aaagtaaaca tgctgcccta
      541 aatattctcc agtttctaca tcagaataaa ctgctactaa attgaaatct gcatgaccag
      601 ttccatcttc tgaccattgt acggtaactg gtgcttcatt gattgccatt ttccaatcgc
      661 cattaatcac ggcttgtggt aaaggagtgc catacagact tacattattc tgaagattgt
      721 agcttttata ttcttgacct aatgtctttc cccattgtgt gacaaaagtt tctaatttgg
      781 aagctttatt cgtatcccac aaagtattct taacctcttc agaagaagat tcagtgattg
      841 aacttgcact tgtttccaca gattgcttca tttctgttgt agtttgttca gttgattgcg
      901 ttttactttt tttagtctca attgttgtat cagtttctat agtcgcttta gtcctcgtat
      961 tctcagatgt acaaccagtg aataaaattc ccattcctat tagtaataac agccattttt
     1021 tcattatatt tccccctttc aatttctccc tcacgtactt attctatcag acaattaatt
     1081 gatctaaatg gtaatctttt aatcgattct ttcccaataa tgtcgatagc ccgtatggca
     1141 gcggtctctt ccttgaggac tctcagatgg attaaaacta gtagaaattt cccttccaca
     1201 tcctctacag cgataagttc tcattatttt tgggctatta gtattatttt tcttagttag
     1261 agctatgagt ccaactatga ttaccccaac tgtcttaatt acttttcctt tatctatatt
     1321 cggatgcgca agcatatatt gatataacca atatccaccg taaattaaac cacctaatac
     1381 aatcagctta gccatgtact cgtctccttt ctttttgttt aattactttt tgaatccatc
     1441 ttgcagagaa accataaact tctgtcaatt gacggatatc tacagttttt tcctgttcta
     1501 tcatgttttc gattcttttt ctaactaact cacgatcgta cattttcatt ggaaaagaaa
     1561 tctgttgccc tcgaaaagca agataaaatt gatagagcaa ttctgaatcc agttccattt
     1621 cctcaaaaaa gtcattcata cttttataag agttactcaa acaagtttca tcaatctcca
     1681 tctacacacc ccctgttatt ttttacataa tgaaaatagc atattactgg gtacattgat
     1741 aattcatata acatgtatca tcacatgtat ttttaaagtc aaaaagcatg taaaactact
     1801 tataagtaac atgagaaaat aaaatgttat ttttcttgaa ataataattg actatctgcc
     1861 aattgccatt cattacgaac atgaatactt agtgggtggg ataacttacc ttctgcattt
     1921 atcaatactt tggtcatctt cttttgtttc gcactcaatt gatcgtaaat agtctttgct
     1981 tgttcataag ccacttgact cgtcgctgta atcgaaccac aagcaaaaat aatggtattg
     2041 attttctttt ctgtaaaaac agtcgttaat atttccaaag attgttcatc atttcctcga
     2101 agaaataccc gaggactttt cgcttttgtg tacgaaaaaa gattcacagc aataaaacca
     2161 gtaaatccta attgtcggat attcttttcg attaataaca tactcaaatc attcgtaaat
     2221 ggttctgtat ctgttggacg aatagtaatg actactgcta atttatcttc cgcttctttt
     2281 cctttgatcg cccattgtcg tttgaaaaca tagcgatggg tatgatgagg atctcgccaa
     2341 acttctgttt gtgtggtcac taattctttt tcaatcatct ctttttctcc tatgctattt
     2401 tttgttcaag cacttcaatt accattgccg ttataagtgt caatactagt tgaaaatatt
     2461 tcatattctt tctccttttt tcttcagaat ttgatgaatc gcggtaagga tatcttctaa
     2521 acatttcgca atcattctca aataatcgat cttattcatc cgttcctcca atctgactcc
     2581 aaaccaatcg tccttctacc agtaacccac gaacaaattc tcgctggctg gtaatatctg
     2641 taatgaaata aactacatag tcttttccat cttctggtgc gcaataaata taaagatgtg
     2701 tcatcactaa acgtggtaga tgaacatctt caggaagcat acccatttca atttcctctt
     2761 tttccatcgt aacggattca tagccccact cttcagaagc agtgaccagc tgtgcacact
     2821 tttccagtac ttcgatagcc gtttctaaca agtcctttcg ttcctttctt ttagatacta
     2881 gtattcttct ggtaataaca tcgtttgata ctcacccgaa tcaatggccc atattttttg
     2941 agacactgat ttcaaacgaa gcttaggtga aatcagatac tcttttcttt cttccggttc
     3001 ttcttgacga tgaaccaact tttgatttcc tttttccgta gaaaattcaa aaatttgaag
     3061 atagtctaaa ggaaattgct tttgaacgtt ttgatcgatt agattccaac ataaagcttg
     3121 taattccacc ggcaaactgt ccattactcc ctttgtgaca taacgttatc ctttattttg
     3181 aaacatttct tttccctcct ttgccataaa aatagcccaa tcttctatta aagaagattg
     3241 ggcttcatgg atataatata tatttgtaaa taaagttaat tcagttataa ttatcaaaac
     3301 tacacaatta ttaaagtttt tcatatctct ttgtttagta agtttttcta aatcttaacc
     3361 cgtggtgcta gttaattttt tcctagagga aaatgtctaa acatgttggt aaatcaacaa
     3421 aaaaacgcat atagtagtct caaaactccc aagaaatgag gactatttaa caaactacga
     3481 tggttacgtc gtgacaactg aacattttga cttagccaat cctgttacta aagtcgatga
     3541 tatccccgat tatgaaatgt acagtcaaac aatcgatagc ttaaataagc gttttggcaa
     3601 tcgtgtttta aaaggcatca aaatcggtta catcgcttct gaaaaggatc ggatcatcga
     3661 ctatttagcc gataaagatt acgatttaaa attactcagt gtgcatcata atgggcaatt
     3721 tgattattta gatgacgaag tcaaagatat ggatcctgct attgtgattc ctcagtattt
     3781 tgcacaactt tcagaagcac tagttgttat agaagcagat gtctttgctc attttgacta
     3841 tggttttcgg gtatttggtc tatccgttgc tgaatttaaa caatatgaag cgcagttttt
     3901 accgattcta gatcaagtaa tcaaaaataa attggcattc gaattaaatg ctaagagcgc
     3961 ttacttgtat gacaatttag cgttatatga atatgtcatc gatttatatc tttcacgtgg
     4021 tggtaccttg tttagtgttg gatcagatgg gcattacctt gaacatttcc gtttccattt
     4081 cgatgatctt tttgctctgt taaaagcaaa tggtgtgacg gaattagcga tttatcaaaa
     4141 aggaaagcga attatggttc cattaccagt ctaaaaaaac gtcctcagca tcaaaagtga
     4201 ggacgttttt ttagatttct ttttctaaaa tcggacaaat acgatcttgt tttcctaaag
     4261 gaaaatgttt gatcccgatt tttttaaatc catgacgttc ataaaaacga atacctgcat
     4321 gatttttttc ataaacagtc aaacgtaaat aacgtttttg tttcgtttta gcataacgat
     4381 tcgcttcatc gagtaaccgt tgccctaacc ctttgttttg ataatctttg agcagataga
     4441 gccgttgaat ctctatagca tctttttcat cattgacttt catataacca atgagtattt
     4501 gatgatcctt aataccaata aatttactgg ttgactgtgc caattctact gccaatattt
     4561 cagttgtcaa ttgtgtctgt aaatatcctt gcatatcaag tggatctgcg ccatcgataa
     4621 acgattcata aaaactgaca acacttacaa cttgtaaagc atctagatca tcataatcta
     4681 aatacgctag tgtgatttga ttgttcatct aactcctcct tttgacatag tatactataa
     4741 at
//
LOCUS       DBBGRF010000106         4631 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000106 DBBGRF010000000
VERSION     DBBGRF010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.109"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(977..1150)
                     /locus_tag="ACIZD4_002867"
     CDS             complement(977..1150)
                     /locus_tag="ACIZD4_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991710.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(1153..1551)
                     /locus_tag="ACIZD4_002868"
     CDS             complement(1153..1551)
                     /locus_tag="ACIZD4_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991711.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1767..2822
                     /locus_tag="ACIZD4_002869"
     CDS             1767..2822
                     /locus_tag="ACIZD4_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991712.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2842..3195
                     /locus_tag="ACIZD4_002870"
     CDS             2842..3195
                     /locus_tag="ACIZD4_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991713.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3377..3664)
                     /locus_tag="ACIZD4_002871"
     CDS             complement(3377..3664)
                     /locus_tag="ACIZD4_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991714.1"
                     /translation="MKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAKLKS
                     DSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3677..4495)
                     /locus_tag="ACIZD4_002872"
     CDS             complement(3677..4495)
                     /locus_tag="ACIZD4_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5991715.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAVNENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWMVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
BASE COUNT         1589 a          790 c          637 g         1615 t
ORIGIN      
        1 acttttgttt cgtgttaagt ttctttacat tcctacgcac ctcgagtgta aaatttcttt
       61 attcctccca cgctccatgt tattttatat ttcctttttc atgttatttt tatccagaaa
      121 ccgatcaagt ttttacctat tcccaaaatc catttattcg ttattttttt cactgattaa
      181 gaataattat ttgatgctta aattagctaa aaaagcgatt tgttactgat ataatcatga
      241 tattgcagct gaattaggcg gaaagataaa atgttcgcaa aatcaaagta tcaattatct
      301 tgttttttta taaatttgta agtaaaaatc taaaaaagtt ttcttttaat tggtatatgt
      361 attaaaatca catttaatca cccataaagt atgcgctttc atttttttgg atgagattaa
      421 tatcaataaa taacgatgta aaaatcattt attatgctct tttataagga tattaattga
      481 tctaatttga aaaaaaatca aaatttaaat gttttaatat tacaaataaa atcatgttat
      541 tgtaaaatgg tataaaaaag ctaaatattt tatttttgtt attttattag caggaaaatt
      601 taaatagttt tacaagaatc cgtagaaata tattggtttt gccttcagat taatactgga
      661 tcatattaat ctgaatataa tatatgaact aataaatagc ttaacctcgc tattttgttt
      721 tttctgatca ctatctatac agcattagta aatagaattt taaaaataaa aaaattaaga
      781 caaaaaagta tcaacataaa catatacata tacacgttta tgttgattca cttaatttgt
      841 cctttaaaaa gcacttattt taatataatg ttattttata atcttattac aagctgattg
      901 ttaggcgttg tcctttcatt acatttatta acggttattt tattgtttaa tttattaatt
      961 atttttgatc taaaacttag cttaacaaat aaataattaa ccaaccgcca gataaaaatg
     1021 cgatcattgc taatacataa gcaaagataa aaatatgttc gatcagctta aaccctgatg
     1081 cgattaagca gaccaagtaa aatagaaatt ctcttacaga taatggtaat tttctaacta
     1141 gcatactcat aattaacacc ccaaagtaat attgtatttt gaacatttta catccaatac
     1201 agcatcaatc aaccattgcc aatcaaaaat acaaggcttc attgaagtat gtttttcaga
     1261 tgaaaagata taatataatt tcttcggaat aatattttca gttgttggga tcaagctaaa
     1321 tctaataccg tctaactcat agctaccagc tttctctcca ttaaaaattt ccttagcact
     1381 ttcttctaaa gaatcaaaat atttttcgac agcaatcttt gaagctttta ctattgaagc
     1441 atttcccttt tcgataaaat ctgcttttgt tttaccgaca ataagtaatt cttgatcagt
     1501 aaaatcttct aaaataatgg tagtgtaatt cttatttctt ctcaatcgca tcaggatcac
     1561 tccttaatat aatttatgtt tttataatat cataataaga taaatttgca agcatttatt
     1621 tacacctttt tatttacact ttattataat taattagact tttatgattg catttttttc
     1681 ttataaacag ttgcaactaa tagtaaatag gtgtaaacta ttttcgtacc gaaataccat
     1741 aaacacaaac agaaagaggt cataccatga aagaaccatt attgttttcc gttgacttag
     1801 ggaataaatc agtaaaagaa atgagtacac acgtttctcc actctcactt ccctctcgta
     1861 ttttgaacaa aaatatcatt aattcaggac gtttttctaa tataggttcc tcattaaaac
     1921 gatcactaaa cgtttctgaa tatagcctag taaacactac tgaaagctat tactttggga
     1981 aggatataca cgagctagga aaagatgact acgtgataga atcactaggt tttgggatca
     2041 gcagatacaa gcaggaaacc taccaaaata tcctatcttt ctctttagct aacctagcac
     2101 gtttagaaga tcaatctgat gacgttttaa ccgctaatct agttttaggt ctgccttcat
     2161 ccgactatac cgaaacaatc gtcaaatacg tgatgcaaca agccacacga caacattcag
     2221 ttgaagttga cggtaaagct tataatataa acgtagatac cgtttgggta ctgccacagc
     2281 cgattggaac actatataac ctcctacttg ctgatgatgg tagtgtacaa gatgaaacat
     2341 tgatcagtca gaagatcggt tttgttgata ttggcggtgg cacgaaactt tttgatgttg
     2401 tccaaaattt tgaaattgac gaaaacaatc gtgaacaaaa ggataccggc atttttactt
     2461 tatataatcg tatcgtaaat atgcttgacc ttccgatcag tcctaatgct ttccaacttg
     2521 aaaagattat ccgagaaggc aaagaaaaag gcgtatatct atttaagcca agcggaaatg
     2581 aaagttttga tatttcagaa gtagttgaaa gagaaataaa aacatacacc aatatggttg
     2641 ttgcagaagt tttagctaca ttcaaaaact tcacaacctt agataaagtt gtctttactg
     2701 gtggtggagc ttctattatc gacaaacaac ttgtaaaaga taaaattccg cataccttgt
     2761 ttgttgaaga cagtgaattt tctaatgtaa aaggctttta caagtttggt ttaactcaat
     2821 aaaacagcga aggagatcaa catgaataag ggaaaatcag agcgttatgt agttataatc
     2881 aatagagaaa aggttagcga gttaccttta gcagagtttc ttgaatccga atatgaaaca
     2941 ctaggcgtta aatactctca gacgatcaaa aaagctttga acctatatcg gcgtgtaaag
     3001 aacaatgaag ttacaattat tgaagcaggc aacgatagaa acgatagcaa agtagcagaa
     3061 gtaaagaata aaccaactga tcataaccct attcaacaag agcatccttc aacggttaca
     3121 tccgatcatt cagcaaagaa agaaaagcca atgctgaaag ggttcaatgc accaagtaac
     3181 aaagacttac tttaaaaata aaaaggcgag gttacaatac ctagcctttt tattatgtac
     3241 aaatataaac ataaacatat acgtatacat gtatataaac atgtatacgt atatatccat
     3301 aaacacgtat attaaattta gttaagctat acctaaccgc ttattccaat aaaaaaagtg
     3361 atcagcttta aactgatcac tcaccaaaaa cttcatcata caagttatct atcatttcac
     3421 caagtaaagc tgaatctgat cgaattccta acttttcgct gattttagat agtttctttc
     3481 tttgcgatgg ttgaagcgtg aattgataat ttttcttctt ttcagaacta tcacttttta
     3541 gtttagctac caaagaactt gttgtttctt taggtgtttg tttaggttct tcaactgctt
     3601 caaccacttc aggaacttct tctacttcag cttcagcgaa ttttttaaat ctattttctt
     3661 tcacttcaat cactccttat tcttgtgccg tatcaattat tttgttgtat agcgtaaacg
     3721 tgctttcaaa gaaatcctta ttcttacgat agatattctt atccttagcg aactcagcaa
     3781 tattcttacc ttctaagcta gttgcattaa gcaattcctt ctcttgtaca tatccaagat
     3841 aattagataa cgttggtacc agttctagga actcacgact tgaattagta ttatgtttga
     3901 tcctgctacc gatcgtagcg tatttagttt ccatcagtgt ttcaccagtc ttaatatcaa
     3961 tcaactgttt tgctagtgca tcaatatctt taccaagctt cagcaaagct tcaaaaccat
     4021 ctttagatgg atcagaaatg cctacgacaa gatcagatac agcccaagca ttttgagcta
     4081 gtagacctgc atcattatga gtatcaatca gaattagatc atacttctct ttaagctgtt
     4141 catagttaac aaccatccat ctaaacagta gggttctgtt gttaggcata tcacgcattt
     4201 gcatctcaac ttgttttaaa tcttcacctg ctactaaaat atccatgttc tcatttacag
     4261 ctaaaggttc agctgatcca tgaagatata aatgattgat tgtattctct cttttcgctt
     4321 tactgaaagc atcaggaaat cgttttgata ggttttgcga cttatcttca tcaatataca
     4381 gcaccttcat acctaaattt tcgacagcat atccacctag attgtagatt gttgttgttt
     4441 tacctgttcc acctttttca atgtttccag taatgattga caacttcttt tccatgatta
     4501 aacctccctt attaaccttt tgtaactcca ttatacacta taaacacgtt tatgtatatg
     4561 tttatataca taaacgtgtt tatatttata tttgctttta tattctacaa cataaacata
     4621 tatatgtata t
//
LOCUS       DBBGRF010000107         4593 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000107 DBBGRF010000000
VERSION     DBBGRF010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.110"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            189..2858
                     /locus_tag="ACIZD4_002873"
     CDS             189..2858
                     /locus_tag="ACIZD4_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGC5991716.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2949..3563)
                     /locus_tag="ACIZD4_002874"
     CDS             complement(2949..3563)
                     /locus_tag="ACIZD4_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGC5991717.1"
                     /translation="MINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKAMH
                     MVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPGIE
                     KRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTIIK
                     ITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3683..4222
                     /locus_tag="ACIZD4_002875"
     CDS             3683..4222
                     /locus_tag="ACIZD4_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991718.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4219..4557
                     /locus_tag="ACIZD4_002876"
     CDS             4219..4557
                     /locus_tag="ACIZD4_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HGC5991719.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1423 a          790 c          860 g         1520 t
ORIGIN      
        1 aaaattttta agggtgggac ttttgattcc tacccttttt ttgcgtttat ttttgttata
       61 cgaacaaatt atgaagttat ttattctaaa ttttattttt ttgtgaaaat tagactcttt
      121 ttaagcagag aaaaacaagg atatgataaa ctgaatacaa cttcatagaa atttggtgga
      181 aaataaatat gaaaaaaaat ttaaagtcat tctttagaga aaacggacgc tacgcagcag
      241 ctagtttcct gattccgttt ttgattttag cacttgttta tctaagtatc gggatctatc
      301 ctggaagcag cagaagtatt ttggcaagtg atgccttttc acagttttct aattttcatg
      361 ccagcttccg aaatgttctt cttggaaagc aaagtatttt ttatacatgg aatgcttctc
      421 taggattgaa ttatttatct ttaatttctt actatctagg cgggatcttc acgccactgg
      481 tgttcttttt tccaaaccag atgatgccag atgcactgta tgttctgact ttgcttaagg
      541 tcggctgtgc cggattggct ttttggtttc ttgcacgtac gttcaagatt cctcgctggg
      601 ggcatgttgc acttagcgtc agttacgcat tgatctcatt tatcactgca cattcggaga
      661 tcatcatgtg gctggatgca tttgtttatc ttccattagt gattttgggg attcatcgtg
      721 ttatggatct taaacggccg aaacttttat ttatcagtta tttactcttg tttttatcca
      781 gtttttatat gggttttatg attggcgtat tttctttctt atattttatc gcccgtctat
      841 tgacaaactg gtcagaatat aaaaaaacga ttgttcctta tggtatcact tctttactgg
      901 caggcggcgc ttcaatgatc attgtattgc cagcagtgct ggatcttcgg tcaaatggcg
      961 aggcactgag tcagatcact acgttgaaaa cagaagcgac ttcttatctg gatctaatca
     1021 tgaaaaatat gattggtgtt tatgacacga caaaatacgg atcgattccg ttcgtttacg
     1081 caggtctgct accattagtc ctctgtctgt tttattttgc cagtcggaaa gtaccgttga
     1141 aaaataaatt tttgtacggc agtcttttcg ccatacttat cgcaagtttc tatcttgttc
     1201 cattgaattt gttctggcat ggtatgcatg caccgaatat gtttttattc cgttatgcct
     1261 atctgttctc tttcttagtg ctcctgcttg caggaaaagg atgggaaaag atagaacaag
     1321 acgatcgtgg gctgttgtta ggaatcattt tggtcgtagc tgctctcttt gcggtggcat
     1381 ggggcatcaa acctgaagga agctacacct atgtgacgat gacttccttt gtattgacag
     1441 tggttttctt agggatttat gcttttgctg tgggatttta tcagcataaa aaactttcat
     1501 tcaatcatct gagtatattg ttattattga tcatgtctgc tgaagcactg gtcaatacga
     1561 acagtatgat ccatggcatt cttgatgatt ggaattatgc ttcccgcagt ttatatactg
     1621 atccttatcc tgacttgaaa gctcttgtaa atgaaacaaa aaaagattcc gactcgtttt
     1681 accgcttgga aaatctggat ccagtatctg caaacgattc gatcaactat ggttacagtg
     1741 gtatcagttt gttttcttct ataagaaatc gtaattcttc ctcttacctg gataaattag
     1801 gtttccgttc aagagggaca aatttgaata tccgttataa caataatact ttgctaatgg
     1861 atgggtttac aggaatcaaa tataacattt ctaaaaacga aagcacgttc agtaaatatg
     1921 gcttccgcca agctggtcaa agtggcgact atacactgta tcagaatgtc aatgcattgc
     1981 cactagcatt tactgcaccg ttgtccgtta atgatgttga gcagccagtg acagataatt
     2041 tgaccagtca gacaaacttg atcaatacat tgtctggttt aaatgaacag tattttacat
     2101 tctatacacc tactttgaag aatcagttga atacgacgat cacaaagaca acgactggcg
     2161 tcacttactc agaaacagca gataaccagc caaaagagct cacttgggaa gtccatgtgc
     2221 ctgcaaatac acaagcttac ttaagtttgt tcccaaccaa ttttgcacaa ttagaaagtt
     2281 ctagtgcgac gatcactgtc aatggtacat cgcgaaaaac gcaaatcaac atttctggtc
     2341 aatactatga tcttggctat tatcctcaag agacaacagt gacatttact gcaagttttt
     2401 atggaacgaa agaagtaagt ttcatggagc ctaaagtcgt tggtctagat gttgtagcct
     2461 atcaagccgc aatgaatcag atcaaagaaa aaggtgtcga aatggaagcc actggcagaa
     2521 aagcttctgg gactgtaaat accgctgaag attccatgtt ggtgacaact attccttatg
     2581 acaaaggatg gaaagctaaa attgatggga aaccagtcaa ggtcagcaat ttcaaagacg
     2641 cattcttgat gataaaagtt ccagcaggta aacatactgt cactttcagt tacttgcctg
     2701 aaggatttac gataggtgca atcctttttg tcctatgtat tgcattgttt attctttatg
     2761 tctggtacct tgaccgcaat cgcccctttt atggcacgat tgatccagca atagaagaaa
     2821 aaccgcgaaa tacacacaga agaagacgaa gaaaataaag aaacgatgga atctgtgtca
     2881 ctcttctatt taaatggcaa aaatttcaat ctttaaatga caaaaaccac ctgatttttg
     2941 gtggtttttt atatacctat gactaaacta tctcttgctg cttcgacaac ttctacagtg
     3001 atcttatcca tttgattgat tcttaaaatc cgatcaatct gcgcaaataa acgatgaata
     3061 agcctaaaat ttccttttgt gatcttaatg atagttgtga tagcctcata atcagaaaaa
     3121 tcttctagct tgatatcaat tcctaaatct gcccatttgt attccaaaat atgatgtgtt
     3181 tcgtccttac taaggttatc aaattcatgt gcaaatccta tgcgagagta aagctgcgga
     3241 taacgagaca atcttttttc aataccaggc ataccgataa gaaccattgc cagatcattt
     3301 ctatcgtaaa tatctcttag ctgttctaaa tgctgaagct ttaaacgatc aatttcatcg
     3361 acaataatta agtcaattgc ttcataggtt ttaggcacag gaggatcttc ttgattgtat
     3421 tttagtacca tatgcattgc tttagtcaga cctattctac tagttattgt gttaatatcc
     3481 gaactgacac gagacatctt ttcagctggt acagtataaa aaactttatt tacacttaat
     3541 atttcatctg ttgcatttat caagaacaag aaaaagtctg aatattcaaa aaaaataacg
     3601 gtgtacattt ttaaaaggag atgtataatc gagatttaga aagcgttttc ctcaaaattt
     3661 aatgaattag gaagtgatta ctatgaaaaa attatttagc gcacttttta ttctgttatt
     3721 tggctttatt ggtattggga cttctggaaa tatagttaaa gctagcacga tggttgaaca
     3781 aacaagtgaa atggcaaaaa cttttagtca attaacacca gaagaacaaa gttacttcaa
     3841 atccaaagga tttagtgata aagatacttt ttacactcaa aagatagagc ctcaagatcc
     3901 gaaaacacgt ttttctgcaa atgtattgcg gttaaccgca tctactaaaa aaattactaa
     3961 tacgcagggg cggacagaat atattataac aagtcccaat tcggcgatgt atcgtatttc
     4021 tacacgcttg agtttaggta gtgcaaaatc atatactcaa acagtaaatc tagctaattc
     4081 ttatggttat ggtggaggaa tgtattttac atttactggg aaaagacaat attacagtgt
     4141 aaaattagct atgcaagttt ataatacatt tggtgtaggg tcagtctctt gcactgcggg
     4201 aggattgaca ataggaaaat gataatttct tactatgtct taaatagaag tgatgatgaa
     4261 ggactcttcg tttttcaatc attacatgag gatacgatgc taaaagagtt ttataatcgg
     4321 attaagaata aacagataga aacaaattta tattttttaa gtgactctat cttgcctttt
     4381 attagcaacc ctaaaattct taacttgttg cagacaaaag atttgaaaag tttaccgatt
     4441 attgtcattg atgaggaaat tgtaaaatat ggcgcttatc taagcgtaga agaattagaa
     4501 aaattaacta acattggaat gagtattcag gaggataatg gggtacatgg aacatagaat
     4561 gaatatgcac agttgagaac ggaatttgac att
//
LOCUS       DBBGRF010000108         4476 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000108 DBBGRF010000000
VERSION     DBBGRF010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.111"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(459..884)
                     /locus_tag="ACIZD4_002877"
     CDS             complement(459..884)
                     /locus_tag="ACIZD4_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991720.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1258..2229
                     /locus_tag="ACIZD4_002878"
     CDS             1258..2229
                     /locus_tag="ACIZD4_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGC5991721.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2261..3658
                     /locus_tag="ACIZD4_002879"
     CDS             2261..3658
                     /locus_tag="ACIZD4_002879"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGC5991722.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3817..4440
                     /locus_tag="ACIZD4_002880"
     CDS             3817..4440
                     /locus_tag="ACIZD4_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991723.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1564 a          719 c          914 g         1279 t
ORIGIN      
        1 aattactacg tgatgtagaa taagcctttc tatcgtttgg ttattttata ttcaaatatt
       61 tgaaataaat aaatctttac tctttgattt gtaaactgaa atgatccact gtttgtttta
      121 ctgatgaagc ttgatcaaag gaagaagctg agtttgaagt tcataaaaat cagccatagt
      181 gagttttgct tggatttgtt tatcttcttc tactttttac ataattttga acaggataag
      241 attcaaatgt tttaaatgaa tctttgacta gtttgtgaca gttgtcgcat atgctcaagc
      301 ttccttggtc attaaattct gtatggatat ttttgttgtt attacatgta caataatcag
      361 gactatcgat catccatttc gtctccttta caatcatctt gcttctttac tatagcagaa
      421 aagaagggga gaaacaaaag aagatccaac agacggcact atagactgta gatgttgcca
      481 tcctcatcct tcaaacggta attaccgatt tttgtaaata tgactgttgt ttctttttta
      541 ttttcttttc ctgaaataat atattcgtca tctttggtag tgatcttgat atctgtcagc
      601 actgtttttt cttcagatga ttcagaagaa tcagttcctt gtgtctgata cgtgcgtgtc
      661 cattccattt ttttatctgt aaatgtcaac tgtcccgcgg ataaatccat atctttacgt
      721 acttttagcg tatatacact gttggtggta tctgcttttt ccgcttttaa gacagaagaa
      781 tcggttgttt cgtccgagga ttggtcagag ccgccaaaca aatcacagcc agtcaatgtc
      841 aaaagtcccg cagacaaaat aaatagtacg attaatttct tcaaaatact tcccccattt
      901 gataggataa agaaattata ccattggaat gtaaaacttc aaacggatgg aagagaaaaa
      961 cgcacaaaac acccacaaat agagtaaatt ttagaataaa attttaaaaa ggcaaaaaat
     1021 ccgccacttt cagaaagcgt tttaaaaaag tgttgcaatc ttttaaaaaa atgctatatt
     1081 aaaaatgaac cggttcaaat acttgtttaa gtataattaa tagtgagagg aagttgctct
     1141 actgaagact ttagttatat ggatattgat gacaagcaac actatgcaaa gaatgcggtc
     1201 atcataatcg aacaacaaga aagagaaatc aaatgtaact ggcaggagtg agaatgtatg
     1261 gcatcgatcc gtgatgtggc taagatggct ggtgtttcag tgggaacagt ttcccgttac
     1321 ttgaatggtc agcaactgaa ggaaaagaac atgaaaaaaa tagcagaagc gatttcagcg
     1381 ttggactata aagaaaacat cattgctaaa gggttgaaga ataatcgaag cttctctatt
     1441 ggacttttga taaacgggat ttccagccgt tttgggtcgg aagttgtctc agggatcgaa
     1501 agagtagctg aagaaaatgg gtatagctta ttattaagcg ggtttgccga tcagccagaa
     1561 aaaattgaac aaaaaattga atacctgatg aagcatgtga tcgatgggct gattgtcttc
     1621 ttatccgaag aagagtggtc tggatttgaa atgctcacaa aaatgagtat tccagttatc
     1681 gcattgaatt gtccagaagg accagcaggt attgatacaa tattagtgaa tgatcgagaa
     1741 agtgtagcaa aagtgatcgc tcatcatggt gaacaaggac ataaaaaaat cggatttatt
     1801 gctgccactc aaacagacta cgtagcaaga gaacgtttag caggagccaa agaagcggtc
     1861 caaaatgatc catcgatcca attagaggtc tttacaggag actattctag aaaaagcggc
     1921 tattacgggg caaaagcatt attagaaaaa ggggcaactg ctatttttgt cagcaattac
     1981 aatatgtcga ttggtgccat cgaatgtttc aatcaagaag gtgtcagaat cgggaaggat
     2041 attgcgttca gtcactatga ttatttagat aaaaacgatc tgagtatcct tccgaaaatc
     2101 acgatcacgc caccaacaga taaaatcggg gaacgagcag cagaacagct gttaaaacga
     2161 atcaaaaaag aagaggaaga aaatgaaaaa gtgattgtga tggaaaatat catacatgga
     2221 atcaactaaa acgaactaaa aaagaaaaag aggtgctttg atgaaaaaat atcaatttcc
     2281 agcaaatttt tggtggggtt ctgcagcaag tggcccacaa acagaaggaa ggatttcagg
     2341 cgatggaaaa ggagagaaca tttttgatta ttggtacaaa aaagaaccgc aaaagttctt
     2401 tgatcaagta ggacctgaaa aaacctcgca agtttatacg aagtatcaag aggatgtaca
     2461 gttgatgaaa cagactgggc ataattcatt tcgaacatct atccaatgga gccgtttgat
     2521 acctgatgaa tctggaacaa tcaacgaaga agccgttcgt ttctatcatc gttattttga
     2581 tgagttgatt gaaaacggta tcgaaccctt tgtgaatctg tatcatttcg atatgccgat
     2641 gtatctgcaa gaaaaaggcg gatggttgaa ccgagaaacg gttgaagcct atgaaaaata
     2701 tgccaaaagt tgttttgaat tgtttggttc gaaagtaaaa aaatggttta ctcataatga
     2761 accaatcgtt ccagtcgaag caggttattt atatcgatgg cattatccag aagagtcaga
     2821 tatgaaaaaa gcgatccaag ttggctatca tgaagcgttg gcttcagcgt tagccatcaa
     2881 atcttaccat gaaatggagc aaggtggtgt tattggtatc atcttgaatc tgacaccaag
     2941 ctatccaaga gacgaatcaa accctgaaga tgttaaagca gcgcaaatag cagatgcgtt
     3001 cttcaatcgt tcattccttg atccagctgt aaaaggcgag tttccaagtg aattgattga
     3061 gatagtaaaa gaacttgatc tcatgcctgt gatccatgca gaggatttga cggttatcaa
     3121 agaaaataca gtagatcttt taggtatcaa ttattaccag ccacgccggg taaaagcaaa
     3181 agaaacacca atcgatacta aaaacggtcc aatgcctgag gattatttcg acaattatga
     3241 aatgcctggt cgtaaaatga atccttatcg cggatgggag atctatgaac aaggaatcta
     3301 tgatattttg atcaatgtac gagatcatta tggaaatatc gactgcttta tttctgaaaa
     3361 cggtatgggt gtagaaaacg aagcacgatt tatcaaagaa gatggcatga tccacgatga
     3421 ttatcggatc gaatttgtcc aatctcatct gaaatatgtc catcaagcca ttcaagaagg
     3481 tgccaattgt ttaggctatc atatgtggac atgtatggat aactggtcgt ggaccaatgc
     3541 atataagaat cgatatggct ttatttcagt agacttagca caagatggaa aaagaacaat
     3601 caaaaaatcg ggtcattggt tcaaagacgt atcagataaa aacggatttg aggcttaaga
     3661 aagaatagtt gagagcaaat gcgtgaaatt ctccattctt accattttgt gaaaaagaag
     3721 ttcaattatt tacgatcttt ttcaactttt ttgtctttct atttcatttt ttgtatataa
     3781 tagaatagtc aaaattaaat aggagtggag gaaagcatga ggaaaaaaag accgtttctt
     3841 ctcttttggt tattcggttt tttcttactg cttattttat ccgcagcatt ttcaggaaaa
     3901 atgacagcag atcttgctca gaaagaaaca gaaaaaatcg tagcaagcaa agaatcagta
     3961 gataatttca aaaaagaatt ctcaacttat tggtgggcgg agtataaaat aactgccaat
     4021 tacgaaaaag gcgaattgga catttatttg ccaaaaggaa aagaagaaaa tcaatttatt
     4081 aatatcgatg acgtacttag tgcgatttct ctcagacaat atcaatttaa agacaagcat
     4141 ttgaccgttt tgcttttgac tcatgatggc gacaaagtag cccgtttgaa aaatggaaaa
     4201 gtgatcaccg cttattctga aaaagtagac aaaaaagtgg tcgccgatcg tttagcggaa
     4261 tggaaaaaga caaatgaaca agtcaagaaa acaactgtct cttctcaaaa aaacgagtcg
     4321 acaggaacaa gtccttcaga ttctggcagt ggacaaacga taacgggaag tgaagaaaat
     4381 caagcctcaa ttattacgaa tgagtcatca caaggacaat atcaatccta tggacaatga
     4441 aaaacagagg ttgtgaaatc agcgttttga cctgag
//
LOCUS       DBBGRF010000109         4430 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000109 DBBGRF010000000
VERSION     DBBGRF010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.112"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(543..2048)
                     /locus_tag="ACIZD4_002881"
     CDS             complement(543..2048)
                     /locus_tag="ACIZD4_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5991724.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDN
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="ACIZD4_002882"
     CDS             complement(2045..2731)
                     /locus_tag="ACIZD4_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGC5991725.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACIZD4_002883"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACIZD4_002883"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGC5991726.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1543 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgcat tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DBBGRF010000110         4409 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000110 DBBGRF010000000
VERSION     DBBGRF010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.113"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="ACIZD4_002884"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="ACIZD4_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HGC5991727.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2945..3379)
                     /locus_tag="ACIZD4_002885"
     CDS             complement(2945..3379)
                     /locus_tag="ACIZD4_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991728.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3396..>4409)
                     /locus_tag="ACIZD4_002886"
     CDS             complement(3396..>4409)
                     /locus_tag="ACIZD4_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HGC5991729.1"
                     /translation="DFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNLNVAMAD
                     RERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKTIEQIKI
                     DNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKN
                     YSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEI
                     GKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNY
                     ISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFN
                     NIS"
BASE COUNT         1363 a          821 c          607 g         1618 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa aagtacattt cttcatgttt ttttcggata tttgtgcttt ttaaccattc
     2521 agcagctgaa aacatataaa aagatatgta tgtattcttt ctgaaattaa gttcatttct
     2581 atgcgatgaa gcatgttttc aaaatattac cctttcttag attaaacttc agagtattca
     2641 aataacggaa taaggagcct tatcccgcat tactgaatga gactgtgaca taagtaaaaa
     2701 ggtgacttca aattccttct tcggaatttg aaatcacctt ctttataatt ataaagtatc
     2761 ggtttcacag catttctgaa tgattcctag aatcttaaac gaatgattgg agttatcaac
     2821 attttttcac tcgtttttag cgaaacaaaa aatgacattt gtcacagcct cattaaatta
     2881 ttgattcttt ttctttataa ttgaattgtc catatttaaa gtgtctagta ctctacatga
     2941 ataattaatt gctttcactc aaatacttat aatctattaa cttgtagttg tttaactttt
     3001 ctgaaaaagt tagacccacg taataatctt cccagctttc tctttcaatt aactgatcca
     3061 atttttgata atccataaat tcatcatgta tcaaaaagaa taaataactt gatattttag
     3121 catctagctt aatcagatta aataatgttt gtttaaaatt gctaccatta atatgactga
     3181 tagattctct agcttcttca cataaacttt ttactttatt aattactact ttgtcatatt
     3241 catttaacac actattatta ccattactta gacgctcaga ttctacgaaa caactcaaat
     3301 cagaaatttc ccaaaaaaat tttttgttaa aatccaattt cctcaactcc tccaaactac
     3361 gtaaatgata tagtctcata ataaaataaa acctctcagc taatgttgtt gaaattgtcc
     3421 actaaaccta attgatattg cttaggagat acacctgcgt actttttgaa tactctcgaa
     3481 aagtgtgaag aatctgaaaa tcctaaacct aaagaaactt cactgatagt atggtttgat
     3541 ttcaacatta ttttagccgt agaaattttt cgcttagaga tataattata aatcgtaata
     3601 tgcatttcat tcttaaagct ttctcttaat ttagtttcac ttacagaaaa ataattagct
     3661 atttccttta cagtaattct tttatagata tttaagccga tgaattgaac gacagaagaa
     3721 attaagggag aaagatgctc tatcttagtt tttccgattt ccttagtata ataaacaatc
     3781 ccagaatccc tcacttttaa gacctcaggt aacgatacag ctaattcgtt ttcttgtatc
     3841 aaagcatctc tactttgata cgcttctatt atatccattc ctaatgttat agacgtttgt
     3901 gctaactttt caaaaacaat gatagaataa tttttttcag accgaatcgt atctccacta
     3961 acacttggaa ttattccatt actcagatta aaaaccatgt tttctaaatt tcgaatatct
     4021 ccatttttaa catattccag tattttattt tcataaagaa acagatatat ttctggatcg
     4081 taattttgtg ataacagatt atctattttg atttgctcga tagttttact tagattttct
     4141 gtatattcaa ttaacggttc atggaataga tcttctattt ttccagtaaa aaaataatga
     4201 actaaaatca gaatatctcg aatgtctcct aaagaataca aagtcaaatt ttgcaatgaa
     4261 ttatagagtc gttctctatc agccattgca acattcaaat tgttcatttt tagtttaaaa
     4321 aaaactttat caatattatt tgctctaaat ggaccaaata agtaatatct ggttttaaac
     4381 atgtatagaa gaaacatctc attaaaatc
//
LOCUS       DBBGRF010000111         4393 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000111 DBBGRF010000000
VERSION     DBBGRF010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.114"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            514..660
                     /locus_tag="ACIZD4_002887"
                     /pseudo
     CDS             514..660
                     /locus_tag="ACIZD4_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            complement(748..1041)
                     /locus_tag="ACIZD4_002888"
     CDS             complement(748..1041)
                     /locus_tag="ACIZD4_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HGC5991730.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            1078..1263
                     /locus_tag="ACIZD4_002889"
     CDS             1078..1263
                     /locus_tag="ACIZD4_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991731.1"
                     /translation="MLEYSGFFIKAVTLKKDIIIVLFFLLLLIGRFILIHYSPLPIIK
                     EKTGSGCSNYMLRKKNP"
     gene            complement(1444..2622)
                     /locus_tag="ACIZD4_002890"
     CDS             complement(1444..2622)
                     /locus_tag="ACIZD4_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5991732.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(2726..3040)
                     /locus_tag="ACIZD4_002891"
     CDS             complement(2726..3040)
                     /locus_tag="ACIZD4_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991733.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3147..3362
                     /locus_tag="ACIZD4_002892"
     CDS             3147..3362
                     /locus_tag="ACIZD4_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991734.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3662..3904)
                     /locus_tag="ACIZD4_002893"
     CDS             complement(3662..3904)
                     /locus_tag="ACIZD4_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991735.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3891..4319)
                     /locus_tag="ACIZD4_002894"
     CDS             complement(3891..4319)
                     /locus_tag="ACIZD4_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HGC5991736.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1388 a          834 c          654 g         1517 t
ORIGIN      
        1 tttttctctt tttattctaa ggttatttta gtcttgtcct ttaatacaaa gattttattt
       61 ttaaataaaa aatactcttt ttttacgatt attgaaaaaa aaagataaaa cttgattaat
      121 tgaagtattg cttaaatttg gaagctatga gggaagaata aaagagttag gacgggatta
      181 tctactattt ttctttgttt taaatatttg ttatctttga acataaaaga gaaatgtgtc
      241 gactgcagtg ttgtgtccct catcacgaat aaacggtgtt caactagctg atcttgtatt
      301 cacttaaaaa atggtaaagt acgagttgct attccccatt ttcaattttc taacgctcag
      361 gacaaaatac tgttttcaca acctcattgg aataaaagca tatatattgt ttcaagaacg
      421 aaatcttgtt atctttttaa agggcatctg tccaaaatct aattttagga ggtacgtttt
      481 ggtatttatt cgtacaaata aaagagaatt atctttattc atgtaacgca tccaattgat
      541 tttttcatgt acgctcctgg aacgatttta ctgacgattg cttatttaac tgcgaatcgc
      601 tcattagctt ttatcatagc tatccatatt ttgaataacg ttcttggctt tgtattatag
      661 atacagatga caaaaaaagt tcaagtatgc ggtgtagaac caatatcgca tacttgaact
      721 tttttcaatg agtataaatt aaaacttcta attttcaatt cccatcatct gatatgcccg
      781 accgtctgaa cttcttttga aaaagccaaa tgtgattaga taacgtcttt gttcgacata
      841 atcgccacta gaaaatacgt tcagcagtat cgaattaacc tctgtttctg tataagtcac
      901 tccatggtca aagcgtttca agacttcttt caataggatg tatttctttt ttgttgaact
      961 tggtacttgt tttacttttc catcattcat gaatgtgtct aaaactttca tcttttcttg
     1021 ctccgtataa gtataaacca tcttctttct ccttttgatt ctaagaatac tccatttatg
     1081 ttagaatatt ctggattttt tattaaagcg gttactctta agaaagatat tatcatagtg
     1141 ctcttttttt tactactact tataggtaga tttattctaa tccattattc tcccctacca
     1201 ataattaaag aaaaaactgg atcagggtgt tcaaattaca tgctaagaaa aaagaaccct
     1261 tgaataccaa gggttctttc tcagtctgat aacaatgatt aacgacggat ttctttgata
     1321 cttgtgaaaa gtcgttaaag tattgatata aaaggatttt tattacctct gactacatat
     1381 tgactaattt gttaaaaaat cgtttttcaa gaatcctgta ataccagtgc tttcaccgtt
     1441 tttttaactc tctaaagaac taaaagcaat cagaggtttt accttttcat ttgacgttaa
     1501 gtggcgataa attttcgaag ttgtttggtc agtatggcct aagcgatctt tcaagacttc
     1561 ccagctacag tgttccgcta ctaagcttgc cattgtatga cgagctaaat gagtatgaaa
     1621 tggcttatta attcctgagc gattcacgca ccgtttgacg tgatcattta catactctcg
     1681 acgataagga acaccacgtt tactagaatc aagatacaca aacaaatatg tttcttctat
     1741 aataaacctg taatgttgcc tcatctcacc caaagcctta atcaactgtt gtagcttttc
     1801 cataactaga ggagttacta gaactcgtct agcagaacta actgtcttag tagtttcaat
     1861 tcgaaaatcc ttactcttac ctttaactgc cgtttgctta tagaacagaa tttcatttct
     1921 tttgaaatct atatctccag gctgtagagc aagcgcctcg ctgactcggc agccagtgta
     1981 aaatagaaca tggaaaagta cagacatcgg taattcctca tgaacaatgc cataattcaa
     2041 aaaagttctc aattcatcga cagtaagaaa cttgtcctca atattattta tggcttcttt
     2101 taaatcagtt accgttaact gatattttgg cattctcaca gacttcattg gattttcact
     2161 tatcaaattc tttctttgac aatatttaaa aatcatattt agaacttgaa taagtgattg
     2221 taaactattt ttggcatagc caacatttgt tccattaacg ccacattcct ttaaggtaaa
     2281 aagcaattct tgaaggcact ctggtgtcaa atcagacaac tttttatcac caatccatcg
     2341 aacaataatt tttaattgtt cctctcgctt atcataggtt atttcctttt gttcatttaa
     2401 cgaacggtaa tattggaacc attgctcacc tacaacacta aacttgtcat tgcttgcaac
     2461 aatttttttc ttaagccttt gttgtttctc catttccaga taagcgagtt gcgcctcacg
     2521 ttttgaatta aagccacgtc ttgttgttcg atatgcttga aagtaccatg tgatcctacc
     2581 agtagaactg atttgcttct tgaatcgatc tgttttttcc atttattgat tcctcctatt
     2641 ttgaaggaac ccaacaagca gaaacccttt ggaaatcttt ctatctatgt catcattgta
     2701 ccgcatctta gaaagaaaat gtaacttata aagatcgaag tagtcgcaat ttttctcgat
     2761 agtcattcga atcactcttt ctcatccatt ctaaaacatc atcacgaaaa tagtgtcctc
     2821 gaatcccgta ccaacaggga ggaaactcac caagttttac taaacggttc agtgtactat
     2881 cacttatctg aaatagtcgc tttaaatcag tatttgttaa taccagaggt aaatgactga
     2941 ctgcaagcaa tttttccgtg taatcttcca gttttttttg taaaattgaa tagaactcta
     3001 tttccagaga attaacattt gttttaactt ccaactccat cacccttctc tctcaaaatc
     3061 aaaacgacca ccacggtacc ccttaaaatt gtaaaaaaac actccagtac tccatcaaaa
     3121 cggactagaa aagaggaatt tttaatatga aacaaggaat tgcagacata aaaataatta
     3181 aagaaattct tgaaaaatct acggctaatg caatagcatt cggaacagga atcaacttga
     3241 gtacagtaaa aaaacttaaa agtggagaga gagctgaaga aaaattaaat cttgccgatg
     3301 ctattaaaat cacagaattt ggcatgaaaa atatgccaac caaaatcgaa atatggaaat
     3361 agtagttttt ctgatctatc agctgttttg ccaaagcaca taggaatctc acctcccccc
     3421 agtaatggcg ggccgatttg gttacggaag tatcattatc gtagtcgcga ttctcatatt
     3481 aaaatttgtc gcttaaaagc taaccttgtc atggcgtaac tagagaatca aaatctacat
     3541 gtactgatag atttgctatt catttgtcaa agagcgctag gctattttca gcctatggaa
     3601 atcctttatt ttgacccgat aaaaaacttc catagaatga aaaggaaagg gaaaaaatac
     3661 tttaacgagt tgtatcaaat tcaagtatct tctcaatcaa ttttgtttcc agttgtctac
     3721 gcatatattc atctacatac ataaccattc ctttttcttc ttcataaact ggtttcatgg
     3781 ctaaccgtga aatataattt tgatattttg acagaacgat ggacatggca attgaatcac
     3841 cagaagctgc ggctttgatt gtcgttagtg gtatgaatgg tatatatcgt ttattttgct
     3901 tcatatttga cacccaaata ctttcctagc tcttccaaag ccatttgtcg ttggtaccaa
     3961 acactgccga gacttttccc aataatatcg ccaatttcac gatcattaag accgatgaag
     4021 aaggacataa aaatgatttc ttgtctttga ctaggtaatg ctgcaatcgc atttgccaac
     4081 tcctcattgg aaataaagat tttcatacca aggacaataa aagtaccact actattcaaa
     4141 tttggttcca aataatagaa ctctgtacct aacccttttt gttccaatat ttccattgat
     4201 atttgccgtt ggcgaaatct agcgtacttc ttttgaatat ttaacgcctc attgcagact
     4261 actttcttac aaaaactgtc aaacgtatgt tgaatgtggg tttcctctga gtcgcccata
     4321 atattctccc cctcaaaaaa ttcattcaac tcgttttact tctatccctt tccattatta
     4381 ctacaatcta gga
//
LOCUS       DBBGRF010000112         4295 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000112 DBBGRF010000000
VERSION     DBBGRF010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.115"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..792
                     /locus_tag="ACIZD4_002895"
     CDS             <1..792
                     /locus_tag="ACIZD4_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGC5991737.1"
                     /translation="FCGYSKTEPRHSFGPAIREQYLIHIVLEGEGYYSINDQKYFLKK
                     GQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYYLKEIGVGKNHLTFKVENLNSF
                     KGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSASYLNEGIITKKMNPFVRQTIEI
                     IRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISIKEYISEIKISIANDLLSSTEY
                     SIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRLGLGIINGE"
     gene            889..3138
                     /locus_tag="ACIZD4_002896"
     CDS             889..3138
                     /locus_tag="ACIZD4_002896"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGC5991738.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3141..>4295
                     /locus_tag="ACIZD4_002897"
     CDS             3141..>4295
                     /locus_tag="ACIZD4_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGC5991739.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1501 a          610 c          790 g         1394 t
ORIGIN      
        1 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
       61 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      121 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      181 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      241 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      301 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      361 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      421 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      481 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      541 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      601 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      661 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      721 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      781 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      841 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
      901 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
      961 ataagttaca tttttaagat atcggaagat ggtaaattat tgcatttata ttatggtgag
     1021 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1081 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1141 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1201 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1261 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1321 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1381 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1441 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1501 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1561 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1621 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1681 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1741 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1801 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1861 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     1921 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     1981 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2041 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2101 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2161 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2221 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2281 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2341 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2401 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2461 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2521 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2581 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2641 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2701 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2761 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2821 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     2881 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     2941 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3001 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3061 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3121 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3181 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3241 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3301 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3361 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3421 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3481 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3541 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3601 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3661 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3721 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3781 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3841 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     3901 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     3961 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4021 cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc tttagtaact
     4081 tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt tttattggct
     4141 gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt ctaacaagaa
     4201 gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg atcctatttg
     4261 taacattttt tgcgacaaat aaaaaaaata ctaga
//
LOCUS       DBBGRF010000113         4179 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000113 DBBGRF010000000
VERSION     DBBGRF010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.117"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..184
                     /locus_tag="ACIZD4_002898"
     CDS             <1..184
                     /locus_tag="ACIZD4_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991740.1"
                     /translation="TILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRR
                     NSSYGSDYTFAITYTI"
     gene            201..350
                     /locus_tag="ACIZD4_002899"
     CDS             201..350
                     /locus_tag="ACIZD4_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991741.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            347..793
                     /locus_tag="ACIZD4_002900"
     CDS             347..793
                     /locus_tag="ACIZD4_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991742.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGVRSDGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYEALEHENGNLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            795..932
                     /locus_tag="ACIZD4_002901"
     CDS             795..932
                     /locus_tag="ACIZD4_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HGC5991743.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADRIISKEESA
                     S"
     gene            967..1209
                     /locus_tag="ACIZD4_002902"
     CDS             967..1209
                     /locus_tag="ACIZD4_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HGC5991744.1"
                     /translation="MKEEALQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
     gene            1225..1422
                     /locus_tag="ACIZD4_002903"
     CDS             1225..1422
                     /locus_tag="ACIZD4_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGC5991745.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            1433..2449
                     /locus_tag="ACIZD4_002904"
     CDS             1433..2449
                     /locus_tag="ACIZD4_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGC5991746.1"
                     /translation="MKKKIILSLSLIMALFLLPINGFAYTINNEFNLGVNEGSSQVAN
                     NQYILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSY
                     ANANSPVQIELQHTHDKVTFEKNYKAYVELARDSANKYGIPLTLDTPYNQPGIKSHLW
                     VTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANP
                     TLSDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYR
                     PDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLN
                     IPKR"
     gene            2564..3772
                     /locus_tag="ACIZD4_002905"
     CDS             2564..3772
                     /locus_tag="ACIZD4_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991747.1"
                     /translation="MTAEIGIMNKSGIVLASDSASTIGDSKVYNTAKKLFTLDSMHSV
                     GIMIYGNAEFNGIPWEIIITQYKKSIGSSVFNTLEEYADNFIEFVKTASFIRSEQTEQ
                     EQMIGVFQKIISGLFESIEVDINFLISQGTQIDKDVLVKLLQTKMNTNLSQQSQTFIL
                     DIEKALFLSNYGEILKDILNSISTMEGVSEAISEEIQSYVYEIIIRDDVYSSPTGIVI
                     AGYGRMDIFPKLYSYNMFGFVMNILKYSEYESAQIGNDNGSLRSTILPFAQSDVVNTV
                     VQGVDPQITNYLSSQVDSFDDNGKNTYINIIKNISEFQQNQFIFPLLNMIALLPVEET
                     AIIAETLLNLTSFKRKYTTSVETVGGPIDVLAITPNDGPIWIKRKHYFDIDNNIGYRL
                     RKERANDYNN"
     gene            3756..3926
                     /locus_tag="ACIZD4_002906"
     CDS             3756..3926
                     /locus_tag="ACIZD4_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991748.1"
                     /translation="MITIIKPQEKSPVLKFNESNLAHNKMSITDTVFDVMVEQQKKIN
                     NNNRQRKEINQY"
BASE COUNT         1520 a          641 c          808 g         1210 t
ORIGIN      
        1 aacgatacta acaattccag aaggctatcg gccaccaatt agttttgagc aactggttgg
       61 ctcgatagac cgttctactt tgaacagtgc tcagttatct attggtgcag atggagccat
      121 taaatggcga agaaactcaa gttatggatc ggattatacc tttgcaatta cttacacgat
      181 ttagaaaggc gtgaatcgat atgaaggcag catatagacc aattgaacct tacggattcg
      241 agcaaatcat tgtgaatgat gaagaacatt taccggaaga atgcacagaa gtcgaaccac
      301 cgattccaaa ttggaaaccg aaattcaatt actgggaggg aaataaatga aaaacatttg
      361 gaaatatggc cgtactggcg gagagtatgc aggaaaagta ttggacgaca tgcttgtatc
      421 cgttccttac acagatcagc caccgctcga aggggttcgt tcagatggcg aaccgctaac
      481 gattgctgat cagatgtttg atcctaaatt gaaccaatgg attattttag cgaacgcgtt
      541 agatcacaac gatttaaaca atctcaaagc gatgtacgag gctcttgaac atgaaaacgg
      601 caacctaaaa cagctaaatg ccaaactcat gctaagcgat gtagcgatta aacaggaaaa
      661 tactgcattg aaagaaaaag ctgacagttt agcacaaatc aattcaaaaa tgatgcttgc
      721 ttcgttacaa aatagcaaag acatttcaga aattaaagag caactaaatc cagcttcaaa
      781 gggaggtgag tagtatgttt agttttagcg atgtgaaaat gatgtatgat tggggctgtt
      841 ttactgacga tcaagttcgt ctattcgttc cactatgtat cacagatgaa gaagcagata
      901 gaattattag caaagaagag agcgcatctt aagtgatgcg tttttttgtt ggaaagttgg
      961 tggaacatga aagaagaagc gctccaagac gttgtggaga gattagtaag aattgaaaca
     1021 aaattagaca actacgaatc acttagagaa aaagctgata gtgcaaaaga tttggcagac
     1081 aaagcctact cagtagcgct aaacaacgca gaagatatca aagaaatgaa agccaataat
     1141 aaatggtcgt ggggttacat gatcggttta ggcattacga tcattggcta tttcttgact
     1201 aaattgtaaa ggagttaaga agaaatgatt ttacccgata agtattatca agtcattaaa
     1261 tggacggttt taacagtatt accagctgca tctgttttag tagccacgtt aggaaaagcg
     1321 tatggatgga atggaacaga tatgacagta ctcactatca atgcagtagc aacattttta
     1381 ggcgttatca ctggtgtgtc tgcatataac ttaaaaaaat aggaggaaaa aaatgaagaa
     1441 gaaaatcatt ttatcattga gcctaataat ggctcttttt ttattgccaa ttaacgggtt
     1501 cgcctatacg atcaacaatg aatttaattt aggtgtaaat gaaggtagct cacaagtagc
     1561 aaataaccaa tacatcctat tgcatgaaac agcaaacgaa actgcgacag gacgaaatga
     1621 agcgcagtac atgaaacgtt cttggtacaa tgcctataca gcgtatattg ttggcgatgg
     1681 tgggatcgtt taccaagttg gacaacctgg ttatgtacaa tatggcgctg gttcatatgc
     1741 taatgcaaat agtcctgtgc aaatcgaact gcaacatacg cacgataaag taacgtttga
     1801 aaagaactac aaggcatatg ttgaattagc gagagattcc gctaataaat acggtattcc
     1861 acttacatta gacacaccgt ataatcaacc aggaatcaaa tcacatttat gggtaactca
     1921 aaacatttgg ggcgatcaca ctgatccgta tggatactta tcagaaatgg gtgtaagtaa
     1981 ggaaaaactg gcttacgatt tagctcatgg atttacagac gaaaacccaa cgacttctga
     2041 gaacaagcct gtcattgatc caacccgagc aggtgcagca aatccaactt tatcagatgg
     2101 aacgaaccat tctcacattg atcagtttgg agaaatcgaa aatgcgaact tacacgtcgc
     2161 tggatggcac atcgctaact ataaatacga gtatattttc attatggact acaatactgg
     2221 gaaagaatta gctcgagtaa gagctgatgg aatttataga ccggatgtaa atcaagctta
     2281 taatacttct ggaaacgttg gctatcatgt atcttttaac atgcgcaatt tccctaataa
     2341 gaaagtatac gtcatgatgc gggcaacgaa tgatccagaa ggaaacacta aaggcggtgc
     2401 gcaagatttc catgacaaac gttggtattt aaatattcct aaacgataaa aatagctcct
     2461 cgttgaggag cagtacatag aattgaaaat taacgttaaa tcaaaaaaat atttacaaga
     2521 tgtttattta agtagataat aaaagaaaaa agcaggtgaa attgtgacag cagaaattgg
     2581 tattatgaat aaaagtggaa tcgtgttagc ttcagattca gcatctacga ttggagatag
     2641 caaagtatat aatactgcaa aaaaattatt tactttggat tccatgcatt ctgtaggtat
     2701 catgatatat ggtaatgctg aatttaatgg tattccttgg gaaataatca ttactcaata
     2761 taagaaaagc attggtagtt ctgtttttaa tactttggaa gaatacgcgg ataattttat
     2821 agaatttgtc aaaacagcat cttttattag aagtgaacag accgagcaag aacaaatgat
     2881 tggggttttt caaaaaataa tttcaggttt atttgagagt atagaagtag atattaactt
     2941 tttaataagc caaggtacac aaatagacaa agatgtccta gtgaagttat tacaaacaaa
     3001 aatgaatacc aatttgtctc aacagtccca gacattcatt ttagatattg aaaaggcgtt
     3061 atttcttagt aactatggag aaatattaaa agatattctt aatagtattt ctacaatgga
     3121 aggtgtttca gaagctatat cagaggaaat tcaaagttac gtttatgaaa ttataattag
     3181 agacgatgtt tattcttccc ctacaggaat agttatagca ggatatggaa gaatggatat
     3241 tttccctaaa ctatattctt ataatatgtt tggatttgtt atgaatattc tgaaatactc
     3301 agaatatgaa agtgctcaaa taggaaatga caatggttca ttaagatcta ctatattacc
     3361 atttgctcag tctgatgtgg taaatactgt agttcaaggg gtagatccac aaattactaa
     3421 ttatctgtcg agtcaagtcg atagttttga cgataacgga aaaaatacct atattaatat
     3481 tataaagaat atttcagagt ttcaacaaaa tcaattcata tttccgttac taaacatgat
     3541 tgctttactc ccagttgaag aaacagcaat tatcgcagag actttattaa atttaaccag
     3601 ttttaaacga aaatatacta cttctgtaga aacagtaggt ggcccaattg atgttttagc
     3661 tattacacct aatgatggcc ctatttggat taaaagaaaa cattattttg atattgataa
     3721 taatattgga tacagattgc gaaaggagag agcgaatgat tacaataatt aaacctcagg
     3781 aaaaatcccc tgttttgaaa tttaatgaga gcaatctagc ccataataaa atgagtataa
     3841 ctgatacagt atttgatgta atggttgagc aacaaaaaaa aattaataat aacaatagac
     3901 aaagaaaaga aattaaccaa tattaatgtt ttttctgttg cgttttttgc agtcataatt
     3961 taaaacctcg ctcaatcttg ggcgaggtct ttttttattt ttctgaaaag ttaaagtaaa
     4021 taatagcata aaataatata ttttacaaag aataagtaca atctagtttt ttgctattaa
     4081 atgtgtaata ataaatatgc catcacaaca tgaagaatga aatccattat tatctagtct
     4141 agtccattct ttttgtttgc agtatttgtg atggctttc
//
LOCUS       DBBGRF010000114         4158 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000114 DBBGRF010000000
VERSION     DBBGRF010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.118"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            180..776
                     /locus_tag="ACIZD4_002907"
     CDS             180..776
                     /locus_tag="ACIZD4_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HGC5991749.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            900..2699
                     /locus_tag="ACIZD4_002908"
     CDS             900..2699
                     /locus_tag="ACIZD4_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGC5991750.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2977..3189)
                     /locus_tag="ACIZD4_002909"
     CDS             complement(2977..3189)
                     /locus_tag="ACIZD4_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991751.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3651..3800
                     /locus_tag="ACIZD4_002910"
     CDS             3651..3800
                     /locus_tag="ACIZD4_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991752.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4053..>4158)
                     /locus_tag="ACIZD4_002911"
     CDS             complement(4053..>4158)
                     /locus_tag="ACIZD4_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC5991753.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1229 a          707 c          728 g         1494 t
ORIGIN      
        1 ttttaaaaaa aacaagttat taaataagtc tttagttgga tgtttttttg agatcaatct
       61 tttatactta tgatgaactt acaaaattgt ttgttttctg tcatatcaaa aaatggcgca
      121 gttagttgct tttctagtaa agtatagtta acaaagaacc tctaaggagt tgatgaataa
      181 tgaatattgc tgcctctcga aaactgataa atttcatatc cattatcgga ttaggcctat
      241 caatcgcgct gacgatttat tttattaatt taggtgtttt caaagatttg aatgcgttaa
      301 gaggattagt aggtgattcc atcattttag gaccgattat ttttgtcttc atccaaatcc
      361 tgcaagtagt tattccaatc attcctggag ggatcagtac tgcagctggt gtcctgatat
      421 ttggccctta tgctggattt atctataact atattggaat ctgcattggt tcgattatca
      481 tttttctgct agggcgtcgt tatggaaagc cattcatact ttccatgatt agcgataaga
      541 catataacaa atatattggc tggctggata atcaaaaccg ttttgagaag ctgtttgctc
      601 tagctatttt tcttccagtt gctcctgacg atgcgttatg tttgatggct ggattgacaa
      661 acatgtcagt gaaacgatat acactaatca ttttgattgc taaaccactg tcgattttct
      721 tatatagtat ggccttgatt tatggaggtc aatatctaag tggtcttctt ggataatatt
      781 tattttgtaa aattagtcat tgattgacaa tgttaaatct gggaaagggt ctgcaaaaca
      841 cactgcaccc tttccttttt cattagattt gcgctacaat gtgaagagca ggtgatagga
      901 tgaattattt gaaacgtagc ttaggtaatg cttgggactt tttaaaagga acacaagctt
      961 atttccgtga tgtcttgctg atgcatggct ttattttatt tatttgttta cccttattga
     1021 gcagtacgac ccgttttatt ttacaccgag gggcaattga ctatttgtct tatgacaata
     1081 ttccttcaat tttttctcaa catcctgggg ttctactctc gttaatcgta gttttgatga
     1141 cgattttact gttagtttat ttcgaattta cttttctttt gatgagtgtt ttttttatta
     1201 aaaagaaaga accaatctct ttgaagcaac tcttacactt gacgatactt cagctgaaga
     1261 aagtgagacc cattactttt ttgtttttcc ttgcttattt tttattgatt ctaccgatca
     1321 gcggattaag ttttaattct gatctactgt caaaaataaa aatccccgct ttcattatgg
     1381 attttatttt tgctaatcgt tggatcatcg tcagttcctt tttactcgtt tatattttcc
     1441 ttggctatat tgggattcga ctgatttttg ctttaccgga aatgattcta cgagatcgtc
     1501 cttttcgagc agccattcgg gaaagctggt cattgaccaa atcgcgtctt ttggccatca
     1561 cgggccaatt tattgtgatt ggcggtacga ttttactcct ttcttcttta ggatatatcg
     1621 ttgttatttt ggcacaaagt atggttgaac aatttttccc agactatgca ttgatcagcg
     1681 ctgtgtttgc tatgacgctt ttacaaggga ttttattatt caatatcgtg atgtctaccg
     1741 tagggatttt ttatatcatt gttgatttca tggatgacga aggcttcttg cctgagatcc
     1801 ctaagtggtt tatcccacaa gcccccaact tgcgtttctc tgcgctgaaa aacactggtt
     1861 tgactctttt tgcagttttt ttcggtattg gcgtctgtct ttacaatatg gattatctga
     1921 cttcagctgt tcagacaaaa ccagtgactg tctctcacag aggtgtgagt acccaaaatg
     1981 gggcgcaaaa tactttagaa gcacttgaaa aaacaagcag agactatcat cctgattatg
     2041 tagagatgga tgttcaggaa acaaaagatg gtcatttcgt agtgatgcat gatgcaaatc
     2101 ttcgtcactt aacaggggta aatggaacac cacaggatct tacattgaaa gaattgacaa
     2161 atcttacagt tactgaaaac ggagtgcaag cccctgtttg ttcttttgat tcttatttgg
     2221 aaaaagcaca taagctaaac caaaaattac ttattgagat caagacctct aaaaaagatt
     2281 cggatgacct tgtcgaacga tttgtccata aataccgcaa agttatctta gagaaccatc
     2341 atattttgca aagtttgacg taccaaaccg tttcagattt aaaagaagca gaaccaaact
     2401 tttatgtggg ctacatctta cctttcaata ttgttgggcc ccctgtgacg cctgctgatt
     2461 ttctgacaat ggaatatagt acgatcaacc gtaacttcat taattctgcc caccaagacg
     2521 gaaaagaagt atatgtatgg acaatcaacg attcagatgc tatgagtcgc atgatgtttt
     2581 atggtgtgga tggtatcata accgatgaga tgggactact aaatgaaagt gtgaaacaaa
     2641 cagatgaaga aatcacttat tcagataaac tgctaaattt tgttttggga gtcggctaat
     2701 caaaaatcgt taatgaaaaa agtctttata caacaaaaaa cgcataacct gccaccgcag
     2761 gtatatgcgt tttttgtttg acgctcataa tgtgtgctta actttctctt gattccttca
     2821 tcgcacgaac aatagctaaa atagcaggaa ttgcagagat cactgcaaga ataattccca
     2881 ttttccctga actttttctt tttggcatat cttctcgctc ccttctgtct ttatttatat
     2941 tataagggag ttcttgcgaa ttctcaaaaa tactgtttaa gaaaccaatt cagcaggtgc
     3001 gctaatatca cagaatttta cgagcatgcg atacttgctt tcattgataa gttgatagtc
     3061 tcgttggtca taactttcaa catacacgac agccgtgttg atatatgtac gttcaataca
     3121 gccgattagt tcatgagata ctccgatcgg tttgcatata taagatcttc ctacttctgc
     3181 ttttaccatt tcattccctc ttttctttat ttttattttg ttttttcttt attttataat
     3241 aacaaattac cttgtatttg aaaacgtttt tatccatttt tttatttttt attttgagta
     3301 tctttctgct ttttagataa ctatttttta acacgatctt agacgttgtg acaaaaacgt
     3361 ttgtttatat tcctatgttg ttcgtgcgtt tttttcttta tattgctaag ttatttataa
     3421 agaggtgagc atatgattta tattcaagca atagtatttg taaccttgat gattgggcta
     3481 cttatcggat taaaagaaaa tagctaaacc atttaagaaa aaataaataa ggaaaatgat
     3541 aaatgctttt taattgcatc aaaaaacgta cgatgctaaa cttggtataa gttcgaaagt
     3601 ttaaaggaaa ctttcaagaa ctaaattaca ttacaaagga gatgaatttt atgacgttta
     3661 caaaaacaaa tatgcaatac cgcgtagctt ttgatacaac ttctaaccgt tttatggcga
     3721 ttgatgcaca aaacgaaaat aacgttgcgt ttggtattac aatcgaacaa gcagtccgag
     3781 cattaaacga atctagataa ggagtgaacc attccaaatg gcgactgatg agatctcgga
     3841 aaatcaataa aagacgtttg taacggtaat ccgcgacaaa cgtctttttg tattcattac
     3901 atatatttgg aaattgtctc tctttatctc tagacctaaa caaaaacaca agttctaata
     3961 tcaaccatct cgttttttat gacaattttg ttagctgttt cgatgataat attccgttat
     4021 tatctgtata atatttaata taatcttaat tgtcaaatta agttagacag atcatcaata
     4081 cttacgtaac tcaaaaatac ttccaaaggt gttcgataat ccagtgattt tctaggaata
     4141 ttatttcgtt tagatgcg
//
LOCUS       DBBGRF010000115         4108 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000115 DBBGRF010000000
VERSION     DBBGRF010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.119"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(35..277)
                     /locus_tag="ACIZD4_002912"
     CDS             complement(35..277)
                     /locus_tag="ACIZD4_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGC5991754.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(309..866)
                     /locus_tag="ACIZD4_002913"
     CDS             complement(309..866)
                     /locus_tag="ACIZD4_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGC5991755.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(879..1067)
                     /locus_tag="ACIZD4_002914"
     CDS             complement(879..1067)
                     /locus_tag="ACIZD4_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGC5991756.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(1080..1646)
                     /gene="amaP"
                     /locus_tag="ACIZD4_002915"
     CDS             complement(1080..1646)
                     /gene="amaP"
                     /locus_tag="ACIZD4_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGC5991757.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            2063..2236
                     /locus_tag="ACIZD4_002916"
     CDS             2063..2236
                     /locus_tag="ACIZD4_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991758.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2876..3349
                     /locus_tag="ACIZD4_002917"
     CDS             2876..3349
                     /locus_tag="ACIZD4_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HGC5991759.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            3358..3585
                     /locus_tag="ACIZD4_002918"
     CDS             3358..3585
                     /locus_tag="ACIZD4_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991760.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         1234 a          740 c          616 g         1518 t
ORIGIN      
        1 tcttcatttc aacataagtt tttcttcaat ttgcttataa tttacgtgca aagaatgaaa
       61 cgactaatac taaaatgatt gcaccgatca atgatggaat gatagccatt cctgcaattg
      121 ttggtcccca agttcctagt aaagcttgtc caattgctga acctactaaa ccagcaatga
      181 tgtttgcgat gatccccatt gatgatcctt tattcgtgat tgctcctgca attgctccaa
      241 tgataccgcc gacgattaat gcccaaataa atcccatttt aaattcctcc taactgactt
      301 cttacttctt attgtacacg tggttcgtta ttttctttga ctttttgtgc acctttgcct
      361 acagcagatt ttgctttatc tgtttggcgt gaagcaaatt gtcctgtgga ttttgctgct
      421 tctgttactt tgtcttgtac tgtttcttga tctttttggt attcttcttg tgttttgatg
      481 tctgcaacat tcacattcac ttcgataaca tctaaatgtg tcatattgtt tacttcagta
      541 ctgatcaatt ctttgatttg gttgtaaata tcttcgatgt ctttaccgta ttctacgatc
      601 acatctagat ccacagctac ttgtttctta cctacttctg tattgatacc tgctgttacg
      661 ttatctgtgt tgactaattt ttcagccata tttgagaaaa atccgccatc taatgtcaat
      721 agaccatcta catctttcaa tgcataaccg atgatttttt ggatgacttt gtcttcataa
      781 gtcaattcac cattcatcat gcggttttct cctttttcat ttgccaaaac tgatccattt
      841 gttgtattca tgtttttgtt ttccatcttt gtttcctcct atgatttaaa aaattgatca
      901 actattcctg actgtttcaa ataaaaaccg attcctgcgc caattgctgt catgattatg
      961 atcaacaatg tcttgaaaaa tccaatcgtt aaccataaaa cagctagcag tagtccaaga
     1021 cccccaaaga taatagggag cttgtatgct gaaaatagtt ctttcattat ttggccctcc
     1081 tattccactc gagagtgctt gtagtctctt gtatcttctt gttcttcata accgctgtat
     1141 gtgactgcca ctttgaccgt ttcttttgtt ccgagtactt tagttacttc ttcttcgata
     1201 tcttgcatca atacacctgt tttccctact aatgaagaag ttcgtttcaa gtctccgttg
     1261 acatggatat ggattcgatt tttcgttgaa cgtatccgta ctttaggtga atgaatgaac
     1321 tcttcttcgt gtaaatggga acgtaccaac ccttcgatcg cttttttgtc gattgttagt
     1381 ttgccatctt cccgtttcat aacgaaagtt cctcttgact ttggatagaa aagaacgact
     1441 agcaagatga taatagcaag aacggcaaat actacagctg cccagaaaat atattgttgc
     1501 atgtagtaat tcgttaaagt aaagaagcga aatcgttcca attgttcagg cataatatac
     1561 ggcgcattga tcaacgcaat cgctagaaat actgaaagta gcagtaaact catgataaca
     1621 ccgattattt ttaacccctt attcattttc cacctcctat aaacttattt ttaccctgta
     1681 aataactcta ccgacaatca cagtatagat agcgaacagt tagcatagca tcagtaaata
     1741 aagcgctacc aaacattgct ggatcataac ggcgttttat tgccagtctg atactgaaat
     1801 aacaattgct tacttattct ctatttactt ttgattgctg gctatactta aaggatatta
     1861 ttcaagatta aaaattgcaa agattatgct cagttattat tacaagattc tatttattta
     1921 ttaaattttt tcggagaatt aaaaaataca ataaataact ttagttactt taatgcgttc
     1981 ttactttatt tttatattat catttttctt attcacttct ttggtttata ctattcttat
     2041 aaataaaaac gaggtatgtc ctatgatgaa aagattgtac tattcattga tcataacgat
     2101 tggctatttg attgtatcaa atctaggaaa tatggtattt ggtatcagta aagaattcag
     2161 ttggactact acattatggg aatctctatt ctttttcatc ttcgtatttt tgttacaaaa
     2221 ttatcgaaaa aaataaacat gtgccatcta tctgttggca catgttttag gatttatggt
     2281 actttttatt cggcaatcca ttttattttt ctacttcttc ttaatacctc taacactttt
     2341 gatttataaa ctaatccaat gcatctactt gcgcttatta agctatttca gctagatagt
     2401 accaccccat gcgtcaatgc ttgattttcc ttttgtataa cattgtataa gcaataaagg
     2461 acaaataagt ggtgattaca ccaaaccatt gaataagaaa aattctgata cgtaaataaa
     2521 catgaacttg aaaaaattaa tgaatcggtt agctactacg tagttgtctt ttttctcata
     2581 cagttctgtt aacttacact tctcttcgct agataataaa aaatcctcca actgtattgt
     2641 ccaatataat cccaggcatc taaactagca ttatagaaga gacacacata gaatctaaaa
     2701 taactggttt taaatgtttc ttacaatcaa aaaaagctgt taaatgcact ccacaccttc
     2761 atactctatc attttttata aacgatatat ttttattgtt tttcgataaa aaatagttgt
     2821 tttacaataa ttattctgct atattttagc tatcaaagat aaaagaggga taaaaatgaa
     2881 atttaaaaca ttgctattaa aatttgtcgt tttaggtata agtgccgtat ttattttgtt
     2941 cggcgtactt ttttatactc agatcgctac aagcgaaaaa ggattcaatt ttgattggca
     3001 gaccacatta tttgtttctg tcatttactt tgcccttctc ctagggatcg ttattgctta
     3061 tttcttattg aaactattga aaaaaatcga agataaccaa gctttttcca ctcaaagctt
     3121 aaacatacta aaaaaaatcg aacgaaccat tttgtttatt ggtttcgcct tttttggctt
     3181 acttcctaaa tttatgaaag tagcggattt agacgatgct ccaggtttga tgttggtagg
     3241 aatcgctgtc gtattcattc cttttgcagt atacacatta acaagcgtgc tggaaaaact
     3301 gcttgaacat gcgattttac ttaagacaga tcatgatttg acagtgtgag gtgcgacatg
     3361 gcaattatcg ttaatttaga tgtagtatta gctcaaaaaa aaatgagtgt gactgaattg
     3421 agtgagaaag tgggcattac gatggcaaac atctctattc taaaaaatgg aaaagcaaaa
     3481 gccatccgtt tttccactct cgaaaaaatc tgccaagttt tggagtgtca accaggtgat
     3541 ttgttgacct ataaaaatga ctcgaatact ataccagaag aataaaataa agtagaacaa
     3601 acagtaaata aaaaataatc tgaatgatag atgtgtgaga cttttagaag ttatttacgt
     3661 ctattattca gattttttat ttcgattgaa taccgtttta tctataaata agatatgtac
     3721 tgactcatac aaagggggcc ttttcttctc catgtactat cacttttcct gatacaactg
     3781 gtttcctgtt acgttgtagt tggatctgct tttagtataa tactttattc attccaccag
     3841 actgatagca gtttgagcag tctaaataat catgtagtat tacaggccat tctgtttcat
     3901 accttgaagt gcttaaaact tcagctaatg gcccattgtg ttaactctta ctccattctt
     3961 ttttagtaag ctcccatata tactgtaaag ccttctatat attatgtcat gttgcttttt
     4021 aacatttact atgtagtttt gataaaatga tttgaataac agtgatggac aattcttttt
     4081 tatttttaac attattttga taataatg
//
LOCUS       DBBGRF010000116         4082 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000116 DBBGRF010000000
VERSION     DBBGRF010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.120"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..143)
                     /locus_tag="ACIZD4_002919"
     CDS             complement(<1..143)
                     /locus_tag="ACIZD4_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HGC5991761.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTI"
     gene            complement(465..686)
                     /locus_tag="ACIZD4_002920"
     CDS             complement(465..686)
                     /locus_tag="ACIZD4_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991762.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(784..1029)
                     /locus_tag="ACIZD4_002921"
     CDS             complement(784..1029)
                     /locus_tag="ACIZD4_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991763.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1269..1883
                     /locus_tag="ACIZD4_002922"
                     /pseudo
     CDS             1269..1883
                     /locus_tag="ACIZD4_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2253..3254)
                     /locus_tag="ACIZD4_002923"
     CDS             complement(2253..3254)
                     /locus_tag="ACIZD4_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HGC5991764.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3413..3679)
                     /locus_tag="ACIZD4_002924"
     CDS             complement(3413..3679)
                     /locus_tag="ACIZD4_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5991765.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3669..4025)
                     /locus_tag="ACIZD4_002925"
     CDS             complement(3669..4025)
                     /locus_tag="ACIZD4_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC5991766.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1291 a          740 c          541 g         1510 t
ORIGIN      
        1 taaatcgtag tatgacaaac atttattcca cgatcatata acaattcctg aacttcacga
       61 tagcttagat tgtaacgcag gtagtaacca acagcgacaa taatgacgtc ttttttgaat
      121 tgtttgcctt taaaatgatt cattactctg tcctctctgt cttttttctc aattttacac
      181 taaaatagat tttttggaaa actttgcaac agaaccgttt ttactatata cttcttccca
      241 gaacttgtcc gtctccttca aattatctct acctctcgag ttcattgggt ggtttgccca
      301 tttattaaac atggaatcac ctttctcata ctcatatatt tatgtcctat ttcaattata
      361 tttatatatg cttaaataaa tttgtatcct gaaatttatt gtaatatgaa gctgtatttt
      421 acatatagta accaaagagt taataaaata aaaagagcga accattatag atcagctctt
      481 ttttcattgc tgtttttaat cttatctaga atcacttcaa atgtttcaaa ggtatttaca
      541 tctaactgac ataaccaaag caagtacttc ttttctttgt aagtccaatc aatattacgg
      601 taagaggaca ttagattatg gtaccttgct ctttgttcaa ctgaagccaa ttcccagcgt
      661 ttttcaaata ttttttcttc ttccattatt gatccctcgc aagacgctac ctcaaactta
      721 aataatgggc agcgaaagtc taattcctta gatctaagta tagcaaacaa atatgaaaaa
      781 aacttagaag gtagtaaaag ttcttccgtc ttttgctttg cttctattct taatgtgttt
      841 cgttatcggt gccctacaaa gattttcatt aattacacac tcatttattg ttgtgtattt
      901 tctgacattt ctctcttgat caattatttt aattccatgg gcatcctgat agttcatagg
      961 agaggagcgg ctatcagaaa tagttgcacc tatctcttga acttctttta caacttctgg
     1021 aaaatccatc catcctgctt cagctgtcaa aagtaataat ctataatatt tatctttcct
     1081 tttcaatcta agaaatcgtc accccattct ttttcttcta ttataaacta tttaactttt
     1141 agaattcaaa aaccgtttgt ctatttagag tttaccctaa atagacaaaa atataacatt
     1201 gaaaaattta gagttctaac gtatgattag ggtgtattat aaacgttata gaaaagtagg
     1261 gaataaattt gaaaattgct tatattagag tttcatccat cgatcaaaat gaacaacgtc
     1321 aaattgaaga aatgaaaaag tttggcgctg aaaaaatttt tatcgaaaaa caatctggag
     1381 cgacgattag tcatcggccg attttccagg aagctttaga ttttgtcaga gagcaagata
     1441 tttttattgt agaagccatt gatcgacttg gacgcaatta tgacgagatt atcgattcag
     1501 tgaattatct aaagaagaag aatgtgcgac ttattatcac cagtttaccg atcatggctg
     1561 aagcaattgg aaatcctctc ctagataaat tcatcaaaga cttaatcatt taaatctcag
     1621 ccatgattgc tgaacaagaa cgtactgaat cgaaacgacg ccaggcacaa ggaattaaaa
     1681 tcgctaaagc aaacggcgtc tataaaggtc gtcctaagtt atacagtgca gacaccaaag
     1741 atcctcaacg tcgccttgtc tataggagta tcgttcagga tcttgagaat ggggttgcta
     1801 tctcaaagat tgcaacagac tacaatgtga ctaggcaaac aatttaccga ataaaaaaag
     1861 aaatcgacca actaattgta tgatttcttt tttgaatcac gtaattatta attagctttg
     1921 tcatcaatac agacaatcat tttagattca tctagctaag ttgattacat ttatgttaaa
     1981 aagaatttag ttaacataaa tataattgat gcataaatcg tccttattta aaggcattta
     2041 acattgacaa cttagtataa tgtatcttat gtaaactaat aagatttgaa ttttatttta
     2101 tacacactcg ataatagatc aattttatgg tcccccgcat ttacgattgc acaagagaaa
     2161 cataaagtcg acctattagc atttcttttc aattcaaaca ttaaaaaagt ttatacctct
     2221 gctactaaaa aatgaaatta tctatttaaa atttaaaacg gtaaatctga ttcatccaaa
     2281 ttggaaaatg gatcagcctg tattggagct ttgtatttct ccataataac agatatcttt
     2341 ttttcatttt ttaaaaaata ccttttaaat ttcttatagt cctctgaaat caaaatatag
     2401 cgtgatggat actcatcaaa agaagaatcg tattcttcct ttaaaattcc cgatttactt
     2461 aatttttcta gtacatcaaa tactctatca ctcaagtaac tccttaaatt gttatcactt
     2521 tcccattgaa ctacttttct ataagttgaa ttatcagttg aaaagataga attttcatcc
     2581 ataaacgcat atattagcag caatctttca tcattgtcaa attctattgg atcaaaaata
     2641 tctaagttgt catcaaaatc tttatcagtt ccggtaactt ttttgttaat tactgaaggt
     2701 gtcttgtaag aaatagaatc taaatcaaag cgttttgatt ctaaattatt ttgtgctttc
     2761 tcaattaaat aattcacttt ttttgtgaga aaccttctga tattgtcttt gctatatgtt
     2821 ccataaaaac ccttatcttc taaagagtcc ctgtacttct taacttctat atactcttca
     2881 gccaaaactt gtggaactgg ttcatctaag aaaaaaaccc ctacctcgcc tttgctattt
     2941 ttataaaagt aatcaatttc tgctatagtt cccgatctat aattatcaac tggagaaccc
     3001 aacttatggc caaaaatcgc taataatata tcactatttt ctacaatttg tttattaata
     3061 acactttgcc cagagctatt atttatataa gtaggaatcg cattcgtttc ccatcgaatt
     3121 ggcatcaaaa ttacttttgt attatctgta ttttctatat tccatctata tatggtttct
     3181 tctacttcat tcctctttgc tgctatatca cctggtgatg ctataaatac ttttattaga
     3241 tttatggttt tcatttattg tacctttctc tttatgtctc tttaaagtaa tttttgtata
     3301 aaatttattg acttttacac tataggacaa cttttatcta tttagtacaa aaaggcccac
     3361 taaactaatt gattagttag gagcctatta caggtatatt ttcaactcgc ttttaagcaa
     3421 attctactac cagctttttg cctaatgccc tagcgatatc atcaagttta tcgaaagata
     3481 cgttatcccc tctctcaatt cgagcaatag tagattgagt tgtatgtgct ttttgtgcaa
     3541 gctccgcttg agttaggcct gcttcctccc gtgcatgata aagagcaacc gcagtttcga
     3601 gttttcttcc ttcacggtca tatgcttctg caaaatcttt gtctttttgc ttttcttcaa
     3661 tcaatttttt aatcatcatt tgtgaaccac tcctctctaa gttcttttgc atgtttaagt
     3721 tcacttattg gtgttttctc cgttttttta gtaaatccat gggtaatgac ataccttcca
     3781 ttgaccacat ggaaatagat agctctttgg atgtttgatc ctaccttact tcttaattcg
     3841 tacaaattag tgtctaattt tttcacccat ttcaaccgtt gagctactag catcccattc
     3901 ttttctgttt cttctattgt acgtaaaagc ttcgcactat ctttttttgg taatgtttcc
     3961 aaccattcta aaaattcatc atgaccatta ggtcttttaa atgtttcaaa agatattttt
     4021 tccataccca attatatcat atattgattt tatattatag tatataacat aaaaattcga
     4081 at
//
LOCUS       DBBGRF010000117         4063 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000117 DBBGRF010000000
VERSION     DBBGRF010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.121"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            82..1431
                     /locus_tag="ACIZD4_002926"
     CDS             82..1431
                     /locus_tag="ACIZD4_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HGC5991767.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1559..2149)
                     /locus_tag="ACIZD4_002927"
     CDS             complement(1559..2149)
                     /locus_tag="ACIZD4_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HGC5991768.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2296..3648
                     /gene="brnQ"
                     /locus_tag="ACIZD4_002928"
     CDS             2296..3648
                     /gene="brnQ"
                     /locus_tag="ACIZD4_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGC5991769.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1169 a          744 c          789 g         1361 t
ORIGIN      
        1 ttttggaatc ttagttgtgt ttttcagaaa actctcttaa tatggaagta attaaacttt
       61 tttagttagg atgatttaaa aatgaatgaa gagcaagaac tgcagcgtgg actgaaaaat
      121 agacatgtcc aactgatttc tattggcgga gcgattggaa cggggttgtt tttaggttcc
      181 ggaaagtcta tccagctagc tggcccttcg atattgctcg cctatcttat tactggatgc
      241 atctgttttt tcattatgcg tgcgttaggc gaacttctgt tatcaaacac caataaccat
      301 tcttttctgg attttgttgc agaatatctt ggcaaaaaag cggctttcat cactggctgg
      361 acgtattggt tctgctgggt atcgattgca atggccgatt taacagccat cggaatgtat
      421 gtacgctact gggcgcctgg tgttcctcag tggcttcctg aactgattgc attaggtctt
      481 cttctttgct tgaatatggt ggctgtctca ttgtttggtg agttagagtt ttggtttgca
      541 ttgatcaaag ttgtagcgat cattgccttt atcctcgtag gagcttatat gatcctcacc
      601 cactatacga cagatattgg cacagccagt atcacgaatc tatggtctca tggcggattc
      661 tttccaactg gtgcaaaagg atttatctta gctttccaaa tggtaacctt tgcttttgct
      721 gggatagaat tagttggatt agtcgctgga gaaacagaaa atcctgaaaa agtgttgccg
      781 gaagctatca ataatattcc tatcaggatc atcttatttt acttaggatc tctttttgtc
      841 attatggcaa tctatccatg gaacagcttg aatccagata acagtccatt tgtagaagta
      901 ttttcggaaa ttgggatcac gattgctgct tccttgatca atttagtcgt attaagtgca
      961 gcagcttctg cctgcaacag tgcaatatat agtacaggac gtatgcttcg ttctttagcg
     1021 caagaaggca gtgcccctaa aaaattcaaa aagttaacaa cacatcatgt gccagggaat
     1081 gctttgacat tttctactat cgtcattttc atttctgtta tcttgaatta cgtgatgcct
     1141 agtgaagtat tcacactagt aagcagtatt gccactactt gtttcttgtt tatctggagt
     1201 atgcttgtct acacgcacat gaaatatcgt aaaagtatcc tcggcaaaaa agctcattca
     1261 tttaaaatgc cgttgtaccc atttagtaat tatctggtat ttctttacat ggcctttgtg
     1321 tgtgtcgtct tgttcctagg aaaagatacg agaatcgctt tattactaac acctgtgtgg
     1381 ttcttgcttc tattactaat ctatcatatg aaatatgaac gtaagaagta agaaagtagt
     1441 tgtgacagaa gtggtcagct tcgagaaata agaaggaatt tacgaaaatt gcttcttaaa
     1501 tttttgtgaa atttcggctt atttcttgga gataaaagct tctgtcccag cctcttttct
     1561 atttccccgg aaacaaccgc tgataatagg catctgcttt tttataggaa aaaatccaaa
     1621 taccagatac aaaaaaacgt ccgaataacc cgatcaacgg tacaaaaaag acaccggcaa
     1681 tcaagcataa gttaatcatc atggagataa gacttcgacg gtcctttgac aaaactctca
     1741 cgacatggga atctggttta tttgctttca tgatttgcct catcaagata ccaaaagaaa
     1801 aactccacat cgtgtatact aagacataag ccatctcagg ccaaaaagct tcagggttac
     1861 gcccgaccca actagtaaca gaaggacata aagtcagcca aaagagcaaa aagatattcg
     1921 accagaccac tcggtaatta attcgttctg ccatctgaaa tatacgatga tggttcaccc
     1981 agatcaccgc aacaaatata aagctgatgg tataagctaa taatgtattt cggatgaccc
     2041 ataaagaatg aaagctagat gtattaggga tcttgatctc taatacaaga actctcaaaa
     2101 caatggctac cactccatca gtaaatgctt ctaatctcga ctttgtcacg atgattcctc
     2161 ctcagatgat tcagcgcttt tattttatca cttacgttat taaataacca tcgttttata
     2221 tagggaattt tctgaaaatt gttgcatatt tttcgaaatt ttgttacttt taaaaaaacc
     2281 gtaaaggagt tatgtatgac aaaaaaatta tcatttaaag actatctttt tataggctcc
     2341 atgcttttcg gtctattttt tggtgctgga aatcttatct ttcccgttca tttgggtcaa
     2401 gaagcaggcg ctgctacctt ttgggcgaat ctaggtttct tggttaccgg tatcggtctt
     2461 cccttcttag gggtgattgc cattggtgta tcgaaaagct caggtgtata tgaattagca
     2521 aaacggataa atcaaacata tgcgatggtt tttaccatct tgctttactt agttatcgga
     2581 ccgttttttg ctttacctcg ccttgcaacc acatctttcg agattggttt agcaccattt
     2641 atcgatccta gcagacagac gctatatcta gcaattttca gtattgtatt ttttgtgctg
     2701 gcttggtggt tttcaagaaa accgacaaag atattagatt atgttggaaa gttcctgaat
     2761 cctgcatttt tggttttatt aggtgctttg cttctccttg cttttttgaa tccactaggt
     2821 tctgtaaatc aagcgcctat tcagccaaat tatcaagagc atgctttttt cacagggttt
     2881 actcaaggat ataacacatt agatgcgctt gctgctttag catttgggat catcattgtc
     2941 acaacaatcc aaaacatggg tgtaacaaaa cctgctgaaa tcgctaaaga cacgatcaaa
     3001 tctggtgcga tcagcattat attgatggga atcatttata ctttgctcgc ttatttaggt
     3061 gctatgagct taggtagctt tgctctaagt gaaaatggcg ggatcacgct ggctcagatt
     3121 gctgatcatt atttaggtac ttatggcagt atcttattag catttatcgt tatattagct
     3181 tgcttgaaga ccggtattgg tttgattaca gcttttgcag aaacattcac agatttgttt
     3241 ccgcaaagaa attacgcatt ctttgttgca cttgctagta tccttccttg tttagcggca
     3301 aacgtaggct tgacgaatat cattcaattt tcgttgcctg ttttgatgtt catctatcca
     3361 ttagcaatga cactgatttt actagtgtta gttggtcctt tgtttaagca gcgtacggct
     3421 gtttatcgaa tgactactta ttttacattg attgcttcga tttttgatgg gttgaacgct
     3481 tgcccagaaa ctatcaaaca aacacctatt gttcaaaatc ttttatatgt tgcggaaagc
     3541 tacttgccgt ttttcaaatt ggggatgggg tggatcgtac cagcagttat cggttttgtt
     3601 atcggactga tttggagttt cgctaagaaa gaagaagtag cagattgata aaagaggttg
     3661 tgaaagagac gttcagcctt gagcaataaa aagtaatttt gaaaaatggc ttctcacatt
     3721 tttgcataaa tttgacttaa taccgagaaa ctgacttttg aacaccgttt attgagaggt
     3781 cgtgaaaaag ccgcttagtt tcaagtatta agaaatattt tgtgaaaatg gcttctcaca
     3841 tttttgcata aatttgactt aataccgaga aactggcttt tgaacaccgt ttattgagcg
     3901 tctataaact gacctgagta ttagagaaac aaaacggcaa agtagctcca tatactttgc
     3961 cgttttgttt tgaactaata ccgaagagaa gctgatcaaa caacatttct tttataatat
     4021 agattttaga catatatatg atataaaaat agttttcgca aaa
//
LOCUS       DBBGRF010000118         4034 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000118 DBBGRF010000000
VERSION     DBBGRF010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.122"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            73..234
                     /locus_tag="ACIZD4_002929"
     CDS             73..234
                     /locus_tag="ACIZD4_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HGC5991770.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..1530
                     /locus_tag="ACIZD4_002930"
     CDS             253..1530
                     /locus_tag="ACIZD4_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5991771.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="ACIZD4_002931"
     CDS             1540..2196
                     /locus_tag="ACIZD4_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGC5991772.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="ACIZD4_002932"
     CDS             2196..3572
                     /locus_tag="ACIZD4_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGC5991773.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3702..>4034
                     /locus_tag="ACIZD4_002933"
     CDS             3702..>4034
                     /locus_tag="ACIZD4_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HGC5991774.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1612 a          440 c          704 g         1278 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catc
//
LOCUS       DBBGRF010000119         3923 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000119 DBBGRF010000000
VERSION     DBBGRF010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.123"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(573..1130)
                     /locus_tag="ACIZD4_002934"
     CDS             complement(573..1130)
                     /locus_tag="ACIZD4_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991775.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1309..1920)
                     /locus_tag="ACIZD4_002935"
     CDS             complement(1309..1920)
                     /locus_tag="ACIZD4_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991776.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2033..2290)
                     /locus_tag="ACIZD4_002936"
     CDS             complement(2033..2290)
                     /locus_tag="ACIZD4_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991777.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2887..3165)
                     /locus_tag="ACIZD4_002937"
     CDS             complement(2887..3165)
                     /locus_tag="ACIZD4_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991778.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3199..3450)
                     /locus_tag="ACIZD4_002938"
     CDS             complement(3199..3450)
                     /locus_tag="ACIZD4_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991779.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1194 a          799 c          520 g         1410 t
ORIGIN      
        1 ttattccgaa taaatggtgt ccaaaagctt gcatctgcca gattatctca tttcttatga
       61 caagctaagc aaattatctc caccaaataa tttattcata tttttgactt gcgcatacta
      121 actaattctt aaattttcat acaaaatttc tcaatttccc ttaacgagta atatttatgt
      181 acggtgattc tcactagtat cccaatcact ttttaagtta tcccgatttc aattctactt
      241 caaaaatagt tgcttttatg tatgctgtta gttgattaga tggtcatttg ttgagctagg
      301 tcgtttattt taaacaagtt gtttctttag cttataccta tctcgtctac caaacgcaag
      361 atggcaaaca caaatgcata cgcatctgta tttgccactt tgattcgtat aaagctaaca
      421 actattaact cctctcagct aatagttgct ctctttttta ttcagattca tttttgctga
      481 tcacagccta gtatttcaat ggttttgaac actaaaccaa attgttccat tacaacattc
      541 actggctgat gaaatggatt agtagatttc gattattcaa agcgattttc tattggtgga
      601 tcgtgttccc aactaataag acggattcca aacctatcgt acagatcttc taaaccactt
      661 ataaattttg cacctatttc aggtgtttta ttgcgtggat attctattgt tacgccatta
      721 aatggatacc aattaggatt aggctctctt tttttctgta catctcccat agaatagtta
      781 gcactttctg ggacataata tattcttcga ccatcctcta attcatctaa taagatattt
      841 cgtgatcgtc tatcacttgc taaatgtaga cgccacgtgc gataccatgc catgctacct
      901 gcatctgcag aaaatccatc aaataatgca acaattgtat cttctatcac aatcctttcc
      961 ccatctactt catattctaa tctaaaatca aactcccctc gggtaatttc tggtcttggt
     1021 ggcttaggac ccaatattat tctacttaaa accgcattcg ttcccagatg aaacacagct
     1081 ataacaacaa taatgattaa tattttgttt ctatttgata aatttctcat tattcgcaca
     1141 tcacctctac attctcacat attagttcgt aatactcctt taatatcaaa atatctactg
     1201 gtcgtaataa tattcgctat gaattcctac tactcgtata agaaaggcca aatcatcagc
     1261 ttttacttgc tgatgatttg gcttgtttct atttatcgta attgttttct aatcaccaaa
     1321 attgttaaca atcggttcag atatttccca gttgattaag gtaattccgt attgtgtcaa
     1381 aacttcttgc gcttctccga aattaagtac agttcttatg tatccacttt ctcctaatat
     1441 aaagtctacc tctcttttaa aaccttcctc gagatttcta agggctatat gtggttttaa
     1501 tgacattgat tgtacatttt cccccatata atattgcgca cttcctcgac taaaatagat
     1561 tcctagatcg tccccaaaag gtagatcttc tctaccacta gctaatctac ttctccatct
     1621 tcgttctctt ttcatagaac ctgcgctgaa ctcacacccg ttaaactcag ctatgacagt
     1681 atcttcaatt atgttaatct gtccatctag ttcgtattca atcctaaatg gaaattctcc
     1741 ataggtgatt tccggttcgg gtattttagg tgagattaat gcaaagaaag gaaatattaa
     1801 gcttggcaac atcaaaaaaa ctcctcctat gatcacaatt cccgatgtaa tccaaaatat
     1861 aatttgtaca attctcattg atccattgta ttccatttta ttccccctat tactattcat
     1921 atccgcctat ctatatcgat cttccaatgc agagataatt gcttccatac cttgattttt
     1981 tactgagtta cctatgcgag atatcattct ccactaaggt gcatcatatt gtctatctaa
     2041 catgattaat tctccaatag gtgtatactc ctccaaaaac aacatttaat gcatctccct
     2101 cgacaacata agctaccatg tttgctgtat atgtgtttga gtctaattca taagcagata
     2161 aatttactgt cgctggatta aatataatcg cattcgtatt tatagctact gaatttgctg
     2221 cttcagcacc accttttgaa tgtccgatca ttgtgatttc aatagtagga tttacgtgga
     2281 cagccctcac cgtttaccct gaccattata gaaatcgctt acttttttga actacgcaac
     2341 aaaggataca atgctcctaa cttcactgtc tccatttttg tccactaagg aatataaaaa
     2401 ataggcatta attcatttaa ttcggtcaca acacgttacc ttttaaatca ttatactgta
     2461 tctcatacat tattatcaat aaactattat aaaaatgcaa aaaatgcttt atcaatctat
     2521 tttgtaattg gtcataatat cattgaaatc ataccctgta tcgatttttc ctatgaatct
     2581 cgtctatttg tgattgacga aaaagaggca agacagacac tggaatggta attttaccca
     2641 ctattttgct ccaactattt gtaatcgtac ccacttttga aataccgaga tgatcatttt
     2701 aattgatatg ctgattccca agcaaaaccc caagaaatta aatgctctat cgcatctagc
     2761 ttcttgggtt ttgcttatat aaattccaac atttaaattt tttatgctgt tcggtctcag
     2821 aaatgccgtt tttgcttata tcacaatatc aagatgtcaa attattcgtg ttgccgatga
     2881 ctttgattaa tttttttcaa attgtttatt aagactaatg ctgtcttttt gcagatacca
     2941 atgttcgaac tttttaacat tatcatatga tcctgcaagt tttaacttct taccattaga
     3001 tgttatcaaa gttataatta accttgcctt tttcccatta ggatctttta ttttatgaat
     3061 tttctgcagg taatctctcc taatggcagc tatttttacc tcatcagtgc tgataaacca
     3121 ttgatcatcc acatacatac tgcctgttat gttgtgtttt tccatttctt ccgagaacga
     3181 aaagtttaag gctcgttctt acttccaaag ttgaatgagt ccatggattg gacttagtgt
     3241 gagaattgag aacaacaata agaatccata tcctcccgca aacatcccta aggctatact
     3301 gtctctccat ccataagtag gattagaaga gaaaagagtc accgtttgta ataatatgaa
     3361 aaggaataat ccagcacaaa caccaaagat aacaactcca aacattgaat ttttatacaa
     3421 tgaccattta tttataggct tttctttcat tttacttccc cctactgttc tgttcacacg
     3481 gaatgaattc aaagttcata agccctcctc tttgaacata tgaatacgac ttgctaacta
     3541 tactttaaaa aagcttgttt taagcggtta taggcgagtt gtaatctcta ttcatctcat
     3601 tagcaaataa cttgccgaaa agtctactga aattaaagca gatagtggaa gaattattta
     3661 gccaggatag acactatttg tgaaacacat gtctttactt ttgaaattct atgatgaaaa
     3721 gccttggaat acagtagctc ttaattggta atactttttc cattataaat aacctctttt
     3781 cattttatat ttatcccctc taaaaataat atctaatcta atattttaaa cttatatttc
     3841 cctcgctgtg ctaatagagc attactaaat aaatagaaac tagaaaaaag cattacgcct
     3901 gccagaataa accaattatt tgt
//
LOCUS       DBBGRF010000120         3617 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000120 DBBGRF010000000
VERSION     DBBGRF010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.125"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            154..417
                     /locus_tag="ACIZD4_002939"
     CDS             154..417
                     /locus_tag="ACIZD4_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGC5991780.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="ACIZD4_002940"
     CDS             417..689
                     /locus_tag="ACIZD4_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGC5991781.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            766..1095
                     /locus_tag="ACIZD4_002941"
     CDS             766..1095
                     /locus_tag="ACIZD4_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC5991782.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1085..1372
                     /locus_tag="ACIZD4_002942"
     CDS             1085..1372
                     /locus_tag="ACIZD4_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC5991783.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1656..2513
                     /locus_tag="ACIZD4_002943"
     CDS             1656..2513
                     /locus_tag="ACIZD4_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HGC5991784.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            2514..3062
                     /locus_tag="ACIZD4_002944"
     CDS             2514..3062
                     /locus_tag="ACIZD4_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991785.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            3322..3617
                     /locus_tag="ACIZD4_002945"
                     /pseudo
     CDS             3322..3617
                     /locus_tag="ACIZD4_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1368 a          466 c          733 g         1050 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga
      841 gtcgaagttg aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa
      901 aaagaatttt atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat
      961 aaagatgaga ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga
     1021 gatattgctg aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca
     1081 gaaattggct tatgaaatcg ttccttcaaa acatgtcatt aagtatttaa aaaagctaaa
     1141 agagaagcca ttgaaagaaa aatttttgaa tttaatttat gatgaaattg cgattgatcc
     1201 atataagggt gaacaaaaaa ctggggattt atcaggtatt tggtctagtg ggttcaaata
     1261 tgcgggcaca acatatagag tagcttacga gattatagaa aacaaggtta ttccagtatt
     1321 gttatgtgga acgcatgaaa acttttatga acagttgaaa aaattaatct agtgatttgt
     1381 tgtcgttctt aagaaggacg gcttcttttt atcgaaaatc tgattcgtct acatgactaa
     1441 agtcgcgagt attctctgct tctcgataaa ttaaataacg tcattacttt gaggaaagct
     1501 ataaatcaat atatttcagc ttttccttat ttatgtacta ccttttactt attaattata
     1561 aggtagtaca tatatatctt tttttggtag taactaaaaa taaatatgtt ataatagtat
     1621 caaatgaata ttgctaaaag aaaagaggta ggaacgtggt agcgaagaaa tatgtaatcg
     1681 gtaattttaa aggtggcgta ggtaaaagta cgtgcgcgca aatgttaggg tttgaatcag
     1741 cagttaatga aggaaaaaga accttgataa ttgacttgga tatgcaagga aatacttctg
     1801 atgtgatgaa cttaacgcat atgaacttca ctaacgaaga aggaggcgga gaaggtgaac
     1861 cgattgttta cgaaaatact gtgactgacg tgttgataaa caatcttcca cctaaagagg
     1921 ctgtctataa agtaatcaat aacctctata tacttccagc agacatgtcc tttgaaatgt
     1981 atgatgattg gatcaaagac caatataatg attcattatc ccaattcaaa tatatgaaag
     2041 aaaagctaga accattattt gatgagtttg acgtcatcta tttagatgtc ccaccttcta
     2101 tttctgtata tagtaaatcc gcgatgtaca ttgcggactg ggcaatcgtc gtcttacaga
     2161 cccaagtaaa atcgatgaga aatgcgatgc aatatcttga gtatatggac ttttttgtga
     2221 aagaatttga tacaaattta tatgttgctg gtgttattcc tttcatgttg gaaagcggtg
     2281 acgcagtaga tcaggaaatg tataaacaag cccaagagat ttatggggaa catttgatta
     2341 aaaatgttgt actcaaaaat gcgcgcttaa aacgatacga cggatcaggt attacgatgg
     2401 agaagacaaa gaaaggtctc ttaaaacaat gggatcgcaa aagccacgaa ttatttatca
     2461 gtattttgaa agaattggaa gaacacgaga attggtatgc ggaggtggag taattggctg
     2521 acatcaaagg acttgatatt tttgggaaca acaaaggact cgccaaaata aaaaaagaag
     2581 cagaagcaaa gaaaaagcag caagcaatta caccatctga aaataagcaa ttagaagtgc
     2641 accaagttca agaaataaaa acttcctcca atgttgaaag acagagtaga ggaagaacaa
     2701 aaaaagttgg cgcaccaatc agaaagtttg ataaggttta ttccaccaag catcctttaa
     2761 aactgtcgac tttgttaaat gcgacttcca gagttttagt agaaaagtat gagactaata
     2821 tgacaagaga tgaattgctt agaaaagctt tagatgagta tattaaacag aatcttacgc
     2881 aagaagataa gcaagatttg tttaatgacg tggtgaaaga actagacttg ttcagagaaa
     2941 aatatccaat tgttccagaa ttagatgatc gtggagaaat aataagaact accagtcaga
     3001 taaaacaaga taccgaagac tcactgcgca aagggtgggg aatgaataat aaagttagat
     3061 aataatcaaa gaagaactaa gtaactacct ttaaacggta gttacttagt tcttctttga
     3121 tttgcatgaa atagagggga tttatttttc tggttacgtg attaaaaaat ccaaaaaatg
     3181 agcataggaa cggttatgat tttagggtgt gttttaatga gatattgtga tttcattaac
     3241 aagtgtatga taatctgttg ttgagttagt aaataagtaa tagagctaac tctaaaataa
     3301 aactattagg aggagatgta ggtgaaaaag tttaaaaaga aaatatattt aggattggtt
     3361 gttggggtga gtatgtttgg gttcatggct catactaaac aagtaactgc agatactaac
     3421 caaaaagaaa ggattatgag ccaattagat gactctcaaa taagtatgta cccaatgagc
     3481 taattgtcag tttaaaggct acacaaagaa tttcaacaga gaaaaataaa ccgcaaaatt
     3541 tattgggtgt aaaagttatg gtggaaaaag atttgactct taggacaaat gaaagcgatt
     3601 gtaataagcg agatcaa
//
LOCUS       DBBGRF010000121         3605 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000121 DBBGRF010000000
VERSION     DBBGRF010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.126"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..191
                     /locus_tag="ACIZD4_002946"
     CDS             <1..191
                     /locus_tag="ACIZD4_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5991786.1"
                     /translation="LVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVT
                     VYEGHFVIAFKSGIEMEI"
     gene            334..558
                     /locus_tag="ACIZD4_002947"
     CDS             334..558
                     /locus_tag="ACIZD4_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991787.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            573..1442
                     /locus_tag="ACIZD4_002948"
     CDS             573..1442
                     /locus_tag="ACIZD4_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGC5991788.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1423..2157
                     /locus_tag="ACIZD4_002949"
     CDS             1423..2157
                     /locus_tag="ACIZD4_002949"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC5991789.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2190..3098
                     /locus_tag="ACIZD4_002950"
     CDS             2190..3098
                     /locus_tag="ACIZD4_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HGC5991790.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3095..3575
                     /locus_tag="ACIZD4_002951"
                     /pseudo
     CDS             3095..3575
                     /locus_tag="ACIZD4_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1252 a          521 c          789 g         1043 t
ORIGIN      
        1 ttttagtaga agatgcctcc ctcagtggcg agaacgagcg aatcaatgag ctgattgaat
       61 ttatccgcaa gaacaaattc cgcaccttag aatatgatga taagcttgta aggaagataa
      121 tccagagcgt tacagtctat gaaggccact tcgtcatagc cttcaaatct ggcatcgaaa
      181 tggaaatatg aaaaccagaa gtaaatagcc catgactcta cagtagagtt gtgggttttc
      241 ttttgcttgc tgattataat aatattttaa taactattgt gtttatcaac caaatggttt
      301 ataatattct tagcgtaaac ttggaggtgc tgtatgacta cggcagaaat gattaaagaa
      361 ctgtgtgagc aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca
      421 cagaatttca ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt
      481 gctgatgtgc taggtgtcaa gtttgtgcag gcatttattt taccagatgg agaagaaata
      541 aaaatatcta acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa
      601 cagagaaatt atcatctttg ccttttatag aaggcatcgt attagggggc tcacgtgcaa
      661 gaggcaccca tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat
      721 ttgacctgac agcgattaat caaattgcta cagaattgga tgataaaaat agaaacaacc
      781 ttgttgtgcc tcccggagcg tggggtgatt ggattaatgg cggcggatgg ttatttataa
      841 atgggtatca tgttgacttg attttacgtg atataaaacg ggtagaacaa ataatcaaag
      901 atacggagca aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa
      961 gtgcaatgta tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct
     1021 tatgcgaatt aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga
     1081 acttttttat atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggtag
     1141 aggataaata ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac
     1201 tatttgcatg taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa
     1261 cttttgaata taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg
     1321 gtctttctct ttttgaatgc tacgatatga ccgagaaact ttataaagaa gtgaatgaaa
     1381 ttgtatcgga gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat
     1441 gatgataata tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct
     1501 ggtgcgggag aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg
     1561 cttgatttag gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc
     1621 tctgtagtag gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat
     1681 tttccacaga ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc
     1741 tttgatgtaa tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata
     1801 aaaaagatat ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct
     1861 gtttttactg ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat
     1921 ttcccggtgg acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag
     1981 gttacaaaat atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt
     2041 ataataaatc agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg
     2101 gcggatgaaa tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa
     2161 tatagaaaaa ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag
     2221 tactttcttt agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg
     2281 caaatattaa tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg
     2341 atatagaacc gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga
     2401 tgcaaaagcc ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta
     2461 tgctatttga tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata
     2521 attacctaaa gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa
     2581 gggacatagt tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg
     2641 atgattgctg caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta
     2701 aggaaatttt atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa
     2761 tgatatcatg gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata
     2821 agtttattga aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga
     2881 tggattccta tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg
     2941 tatccggtga ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa
     3001 caaaatatac cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca
     3061 catatgccgc tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca
     3121 cctgaaagat atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag
     3181 gtatgaaaac gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag
     3241 ctaccaagac gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa
     3301 tactgataag ataatatatc ttttatatag aagatatcgc cgtatgtaag gatttcaggg
     3361 ggcaaggcat aggcagcgcg cttatcaata tatctataga atgggcaaag cataaaaact
     3421 tgcatggact aatgcttgaa acccaggaca ataaccttat agcttgtaaa ttctatcata
     3481 attgtggttt caaaatcggc tccgtcgata ctatgttata cgccaacttt gaaaacaact
     3541 ttgaaaaagc tgttttctgg tatttaaggt tttagaatgc aaggaacagt gaattggagt
     3601 tcgtc
//
LOCUS       DBBGRF010000122         3270 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000122 DBBGRF010000000
VERSION     DBBGRF010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.127"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            4..588
                     /locus_tag="ACIZD4_002952"
     CDS             4..588
                     /locus_tag="ACIZD4_002952"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGC5991791.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(664..1839)
                     /locus_tag="ACIZD4_002953"
     CDS             complement(664..1839)
                     /locus_tag="ACIZD4_002953"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGC5991792.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            1921..2301
                     /locus_tag="ACIZD4_002954"
     CDS             1921..2301
                     /locus_tag="ACIZD4_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HGC5991793.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2375..2737
                     /locus_tag="ACIZD4_002955"
     CDS             2375..2737
                     /locus_tag="ACIZD4_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991794.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1112 a          534 c          618 g         1006 t
ORIGIN      
        1 aatatggcat tcccacaact agatttaaaa agtgaaaaag gaccaaaagc tgttatcaaa
       61 acaaaccgtg gtgacattac tgttcaatta ttccctgaac tagcaccgaa gacggttcaa
      121 aatttcattg aactttccaa aaaaggttat tatgatggcg tgatttttca ccgcgttatt
      181 cctgatttca tgatccaagg cggcgatcca actggaacag gaatgggtgg cgaaagtatt
      241 tatggcgaaa gttttgaaga tgaattcagt cgtgaactgt tcaaccttcg cggagcttta
      301 tctatggcaa attcaggtcc aaacacaaac ggaagccaat tctttattgt aaataacaca
      361 aatgtgccag ctaatatgct tggacaacta gaaggtgctg gattcccatc agaaatcatt
      421 gaagcgtata aaggtggcgg aactccttgg ctagatttcc gacatacagt ctttggacat
      481 gtactagaag ggatggacac agtagatgaa atcgcaaatg tacaacgtgg tccacaagac
      541 cgacctgtac atgatgtagt gattgaaaca attgaaattt cagaatagtt tggtatggta
      601 cggagtaatt atgaaaaagg acgaaaccta gtaaggtctc gtccttttat tttgaataaa
      661 tatttaatcg attgtctcta aagcatactt gattcgatta agtccttcca gtaaagtttc
      721 ttctggacaa gcaatattca agcgcatatg cccatgaccg gaaggaccaa acgtgatgcc
      781 aggatttaat acgacttttc ctttccgaac aagagtgttc tccaattctt ggtcgtctga
      841 aatataggcg gtaaaatcta accacattaa gtaagttcct tcagggttca ttattctcac
      901 tttcggaaga tactgttcaa aaaactgatt aactgtttga acattttttt ctagataagg
      961 aatcagttgg cttaaccatt ctccacccgt ctcataagcc gcttgggttc caatcagtcc
     1021 aaaagtgttg atttcgtgct gttggttcat cactaaatgt ttttcaaaat cagctttcat
     1081 ctctggattt ttgataaata ccattgaatt tttgattgca gctagattga aagtcttggt
     1141 tgcggaagta aaagcaacta gtagatcatc taaattagga tcaatcgtta gcatggaagt
     1201 aaatgtatga tcgaataaag ttaaatcttg atggatctcg tcactaaaca gaatcacttg
     1261 atgttttaaa cacaattcgc ttaactgttt caattcttct ttgctccaaa cacgccctcc
     1321 aggattgtga ggattgcata aaatcattgc ttttacattg ttttcttcga tttttttctc
     1381 catgtcagac aagtccatga tgaaatgatt atttttttct agcaaagagc ttcgaacgat
     1441 gtgacgttga tttgtttcta taatagagga aaatggagga taaactgggt catgaatcaa
     1501 aatagaatcg cctggttttg taaaagtttg tactgctgca gctaaactgg ttaacacacc
     1561 acttgtaaaa acgatatttt ctttcgtcaa ctccacagca tggtgttggc gttcccaatg
     1621 aatgatagcc tgatatagtt tatcagacag agtggcataa ccaaagattc catgtttgat
     1681 gtattcacta aacgctttag ctaccccacc gggagacaag aagtccatat ctgctaccca
     1741 caaaggaagt aagtcatcca tttgatatgt ctcagcaatt gcgtcccatt ttacactttc
     1801 tgtatctttt cttgaaatct gtttatcaaa ttcgatcatc ttaagacctc cagtcatttt
     1861 cgtcgcttct ttttttgagc tatttacagt ataatgataa atgcgaagag agggaagtag
     1921 atgacttata aaattggaca aataattgaa ggaaaagtga cagggataca gccttatggc
     1981 gcattcgttt ctcttgataa cgagacgcaa ggacttattc atgtttcaga agtacaatcc
     2041 ggttatacga aaaatatcca ttcattgtta aaagtcggac agccagtaac agttcagatc
     2101 atcgacattg atgaatattc caaaaaaatc agtttatctt taagaacgtt agaaaaaaca
     2161 aatccagctg ttccatatcg cagaaaaagg tatttcacga ataaaaatcg taagatcgga
     2221 tttaccacta ttgcggagca gttacctatt tggatagaag aagcattatc tgaactagaa
     2281 cggaaagaaa ataagaaata aaaagtgtat tttttctgaa aatgtgctag aatttttatg
     2341 taagccatag aacaagttga tcgaggtgga aattttggca agcaaaagag ttgctggtac
     2401 aattatgttg catttggagg atggtactaa aaaatttttg gtccattcaa ttgatgacaa
     2461 gttggaattt gcgttagcgg aactttctga aggaaagact ggtttagcga atatacttaa
     2521 tttcttaaaa gaaatagttc atatcgatgt tagcaagatt agtttgatgg aattgacaaa
     2581 tacacatatt aaagaggaaa atgttccgtt gtttgtcttt gaaactgaac aaaagaatca
     2641 aagagaagaa ttaggcgaag gatatatttg ggaagaacca ggtcaaatgc gctctgttct
     2701 tggaacttac gaagtagagg gagtgccttt cttctaaaat acagattaag cgaacaaaga
     2761 agtttgaatt tttttcaaac ttcttttttt attgtttggt ccaaaaaata caatgaaatg
     2821 ttctgctaaa gatagttttt tagtgcattt tattttcaaa atatgttgaa aacggttgta
     2881 taacgaataa taataattga tcgaaaaatc atttcacaaa gtaatgctta atttatagtt
     2941 gaccaaggaa gaaatacatg ataaatttaa cagcgttgat tctgaagtgg atgttatatc
     3001 acatttctaa aaaatttaaa aaatagttat tgacatgtta ctaacgacat gataagataa
     3061 ctgagtcgtt aaaaaagaac cacttgcgaa gcttgattct atcgaaaaaa acttcaaaaa
     3121 agttcttgac aaataacaaa cgataagtta tgataaatga gttgctgaaa gatttcgaaa
     3181 aacgaaatcg aaaaaaactt ttaaaaaaga gttgacaatc gcttgtctct ctgatatgat
     3241 ataaaagttg ctacggcagc caaaaacgaa
//
LOCUS       DBBGRF010000123         3200 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000123 DBBGRF010000000
VERSION     DBBGRF010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.128"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..546)
                     /locus_tag="ACIZD4_002956"
     CDS             complement(<1..546)
                     /locus_tag="ACIZD4_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGC5991795.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNI"
     gene            1208..1294
                     /locus_tag="ACIZD4_002957"
     CDS             1208..1294
                     /locus_tag="ACIZD4_002957"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGC5991796.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1596..1820)
                     /locus_tag="ACIZD4_002958"
     CDS             complement(1596..1820)
                     /locus_tag="ACIZD4_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991797.1"
                     /translation="MEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNMTPERKRS
                     LEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            2186..2470
                     /locus_tag="ACIZD4_002959"
     CDS             2186..2470
                     /locus_tag="ACIZD4_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991798.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            2473..2889
                     /locus_tag="ACIZD4_002960"
     CDS             2473..2889
                     /locus_tag="ACIZD4_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991799.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(3026..>3200)
                     /locus_tag="ACIZD4_002961"
     CDS             complement(3026..>3200)
                     /locus_tag="ACIZD4_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HGC5991800.1"
                     /translation="DQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSSLTS
                     DLPKISLRNWLEE"
BASE COUNT         1066 a          597 c          499 g         1038 t
ORIGIN      
        1 aatgttaccc atttgatagt attctgggat atccattaag ctcctaaact cttcaatacg
       61 aactacataa taaccagtag aacggtactg cataagcagt cggaatagag tttttgcata
      121 cgtagaacgc aacgacgtga aagcagataa ttcaaatcta ctaaattcag ctgttaaacc
      181 attaataata tattctaggt ccggattaac actgacttca acaaactttt ttgttttatt
      241 gatttcaaaa ccagtaaaca aaacaaagta gcgaatagaa tcctcatctt cagtacggta
      301 agtaagatta agcatatctt tatagagctt ttctaaatca ccgacaaagg cttttgtagc
      361 agtcatctta taatcactta actcttttaa ttcctcgaaa gaaaatctaa cttttttcaa
      421 accacgatct ttcatacgag cgcataatgc aaaaaataaa tccatctgct tagcattgaa
      481 atttttcagc ggtactaaat tcaattcatt ttgatatttg actgttaatt ccgttttttc
      541 atccattcct ttcttccccc cttacaaata aataataacc tttaacaacc aactcgtaaa
      601 taggttggtt gttattatac aaaaggatat tagtactcag ataaaaagtt gttagtactc
      661 agataaaaag ttgttagtac tcagataaaa agttgttagt actcagataa aaagttgtta
      721 gtacccttct gtatccgttg ggagagtaag gctcaactgc cccctaaaaa gggttctaaa
      781 aaatctttaa aaaataaata aaataaacgc gcgcgcgcga gcaaaatttc ccgccaaaaa
      841 atcacccact ttttaaaata aacaggttcg cgcatgatat taaactgcca atctagctcc
      901 ctatggtcgc tgtaagaagg agtgatcgct acgctctcac attttacttg cagcagtcgc
      961 ctttaggctc cttcgccaaa aataattcat tagggactcc tttgtggcgt cctgagagct
     1021 cgtctaagcc gttctaagac aagattcgat aaaaactatg tccttcgttc taaagcgcct
     1081 tacaggcggt cagggcaagc cctaacaacc ccaaggcaat aaaaaactta ggcttatttt
     1141 tgctttttta ttgtataatt gattgtcgcc tatccgacag tcttgcgact ggaaggaggt
     1201 gtgtttcgtg ttcactaact ttatttgctc ccttcttgtt gggcttttaa gcgctttgtt
     1261 cagttactgg ttgaataacc gaaacaagaa gtaaaactta attaaggcga ctcagcccac
     1321 aaaaaaagcc ccagagaatc cgacctctct ggggctttcg tgtgtttcgt gttcacttat
     1381 ttgcaatcaa attataacag aaataaatat ttatttcaaa aatatcctac aaaagtctaa
     1441 aatccgtaat tatttcttat atgcaacatt tacaaataaa gtcgctctga gagctcgtat
     1501 ttttcgattt aagacgtttt atttagtttt tggtgtattt cattggtcca agctaaaaaa
     1561 ctcttagaag cgattttaga gccatttaaa cccacttaat tatattctcc atgaaattcg
     1621 ctccatgcgt caaaagctgc gtctgaaatt ccgccgtctt cgttcactag ttgcattaat
     1681 ttttccaacg atcgttttct ttcgggtgtc atatttttat attccaacaa tttttcgtct
     1741 gttaaatcga acttgattgc ttgaattgct tgctctaatt tttctaagtt ttgaaaatat
     1801 tcgtaaggaa atttttccat tttttctttc tccagtctca caatttttct agaaataaaa
     1861 tcacttcttt gccgtctata ctctcaaaaa aaatgtcgtt tgaaaaacta aataaatttt
     1921 tgatcgtgca tttttaaatt tggttatcga ttacacgtgc agcactcccc cccgaatttt
     1981 aaagagcata aggaaacgtg tacccacttt ctaaaaaaag tgggtagata ggctgtgcct
     2041 atcacgtttc tcagaaaaaa atttgatatc actttttcgc catcgtgggt agcttatgta
     2101 tagcattttg gcaaaaaaca gctatacaaa tatagtattt gtatggtata cataaattat
     2161 acataattgc aaaaggagat tttttatgga cattttagtt cggaatattg atccaaagtt
     2221 tgttgcaaca atagacaaac gttgccaaga actcacgaat aaaacaggag aaaaatggag
     2281 tcgaaataaa tatctaaaag ttttaatcga aagtgatttt gaccgtcaac ttacgactta
     2341 caaaaaagac caattcgatt tattgctcga taaatttatt gctatccaaa cagaaaatac
     2401 tcaaatatta agcgagtatg tctacacaaa taatcaaatc attgaaatgc ttatcggagg
     2461 aatgatataa ccatgagaaa aacttctgtc caaaaacatg ttactttgta ccctagtcat
     2521 gttgacgttt tagattccat catcgaaaaa aatccagata tcaataacta ctcggaagcc
     2581 attcgctttt tatgtatgag ttatgaaccc gataccaaca cgaccactac cagcaatcag
     2641 gcaaaactaa atgctatggg aaaagaaatt tccatcatga ctgaaatcat cgcagaattt
     2701 gctgatttat atctaaaaga tacaggcgtt cttattggca caaattctaa agtatatcaa
     2761 gaagtgaaag aaaaaatcga agctaaacta aatccatcaa atcgaaatcg accaaagaat
     2821 catcaaaaag aaaccagtca aacagtcact tctagaaatt tcgacccaac aaattttcta
     2881 aaacgataaa aaacagatag gagttattcc tatctgtttt ttatttagaa gccccataca
     2941 atatgctaga atgtactagc aatcttagtc ggttgtaagg gacttgtcta cttgcttaat
     3001 gtaagggggg cgagttcttt tttatttatt cttctaacca gttacgcaga gaaatctttg
     3061 gcaaatctga cgttaggctt gaaaaagtaa attctaattt ggcgatttta ttgccctttt
     3121 ttgcttttat ttttgtgact ttaagatcat tgaagtattt ttttagttct cgtaatgcag
     3181 gatttaatac tttttgatca
//
LOCUS       DBBGRF010000124         3078 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000124 DBBGRF010000000
VERSION     DBBGRF010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3078
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.129"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..193)
                     /locus_tag="ACIZD4_002962"
     CDS             complement(<1..193)
                     /locus_tag="ACIZD4_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HGC5991801.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTG"
     gene            887..1273
                     /locus_tag="ACIZD4_002963"
     CDS             887..1273
                     /locus_tag="ACIZD4_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGC5991802.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            1367..1557
                     /locus_tag="ACIZD4_002964"
                     /pseudo
     CDS             1367..1557
                     /locus_tag="ACIZD4_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            2071..2403
                     /locus_tag="ACIZD4_002965"
     CDS             2071..2403
                     /locus_tag="ACIZD4_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC5991803.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            2313..2507
                     /locus_tag="ACIZD4_002966"
     CDS             2313..2507
                     /locus_tag="ACIZD4_002966"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGC5991804.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            2546..2692
                     /locus_tag="ACIZD4_002967"
     CDS             2546..2692
                     /locus_tag="ACIZD4_002967"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991805.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            2699..2854
                     /locus_tag="ACIZD4_002968"
     CDS             2699..2854
                     /locus_tag="ACIZD4_002968"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HGC5991806.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
BASE COUNT         1119 a          500 c          474 g          985 t
ORIGIN      
        1 caccagtaaa gaaatggaaa tctttagttt ttttaatatt atcagttagt aactttttat
       61 aatcataaaa aaaataagta gttctatctg agcgatactc ttttataata ctgaattcgg
      121 aattaaaaac cacgataggt aactttaaac aaacatgaag agactttaat aagacttctt
      181 tatctgaaaa cacttttgtt tctctctttc ctttctacat cattaaatag tattttatac
      241 gttatctaaa atactattcc tctgtcaaaa taagctaact tacttcatta taaaatatcc
      301 acttatcgct ttcatgtata ttccaccgta aaaagtacat tttatcaccg agaactcatc
      361 atttttcatc atgatgaata ctatttacat atatctagtt caaagacaat aattattatg
      421 atccgttatt atctaagcac tatacagata ataggaattt ttcgtttcta aatattccaa
      481 tttgggaatc caataaaaat tttcgttcaa atacgtgtct attcgaactc ttttctagtt
      541 gttaattatg aagggggaag aaataaaaaa tacaatctat acacgaataa gaatattatc
      601 caaaaggagg ttttagaaaa gatttattat acgtaaaaag ctcaagacat tttcttagcc
      661 ataaggacat gtttgatatt taagaagata tatgaatttt cttttctaag tataaagata
      721 actatccatt atcaactaaa aaaacatttt tgaaaataaa catcagcagt cctatcaatg
      781 catgtgagct tatagaagtt attcgcagcg cagcataatt gcattagctt cttttcgtgt
      841 tttttgcctc ttttcccttt aaatcttaat ggaggaggtg tgcaatatgt cagataacga
      901 cgaacgcgta aatgcccagt tgattcgatt ctttgaaaag gtcattttga acaccgctaa
      961 tacttattat aaaaaacaag aagaaattca aaaacatgaa caacttgatc aactcccacc
     1021 atatttgttt actaaagata ctataaaatt taaacaaccg attaatgttt taaatgtgac
     1081 tctccttgtt gaagatataa aattagcaaa aatccttcct ttgttgaaag aacctgaaca
     1141 aatttttctt atcgaaaaat ttatctttga taaaactgat aaagaaattg gaaaggttct
     1201 ggggattaca agacagggtg cgacaaattt aaaacatcga ctttacaaaa aaattcaaaa
     1261 aatgctggtt taatatctgc ataataacta attttgtatg cttctttgct cgttctcctc
     1321 cttcccaaag aaatagatta taagtccatg ggaagaaggt agatttatga attctttaaa
     1381 agaagatttc attttagcaa aggctggaaa tgaagaagct gttgaggcaa ttctcaaaag
     1441 atttagctct ttgattcata agcaatcctg agaactggaa aatatgatca agattgttat
     1501 caagaatgta tgcttgcaat atatctagct atctcgaaat tcgaaattaa agaataactc
     1561 aactaaggga gtctgtgaca taagtaaaaa gatagtttca aatttcgaac aataaatttg
     1621 aaactatctt ctttataatt ataaagtatc gattttacag cgttctataa tgattcatag
     1681 aatctaaaac gaatgatttt aattatcaac gttttttaat tcgtttttag cttaaaaata
     1741 acttttgtca cagtctcact cctaaaatta ctttatttac gtatgaagtg ggcaggaggt
     1801 cgaatccaga actgggctat ggtacttcaa cgaggacttc tcctctagaa ttgaaaagca
     1861 tgcgatttac cttccgtaac gacggtagat ttattcaact atgtgtccaa tcaaaatttg
     1921 tctgatttca aaaatagtca agagaatttt ggttgttaaa aactcttatc tatcaacttc
     1981 cacagtttag ttgacaaacc ctgatactaa gttgggctat gatacacttt tcttgactat
     2041 cagttacgtt accggaagga atgaactcta ttgagaaaaa catatgatcg taaatttaaa
     2101 ctaaagattt cacaggatat ccttgagaaa aaagtaacta ccaagaaaat tgctgaagaa
     2161 tacaatatct ctcgtccaac aatttcccga tgggtttcag aatatcgtcg atacgggaaa
     2221 aatgcttttg ctggacaagg aaaaagatta cctgataaag cagatttcta cattcttgaa
     2281 caggaaaata aacgactaaa agaggaagac gagtgttcta cgaacacaaa gatcgatacg
     2341 gatctccagg gatcactcaa aaactttacg atgaaggaat cgaaatcaat aaacgtgttg
     2401 tagctgttct tatgcgtgaa atgaatttat gcacaagagg atttcatcga cgcaaatctt
     2461 ctcatggtag agaaaaaaca atcaaagaaa tggtaaaaaa atgttgaatc gataatttga
     2521 acagaaccaa attgatgctg tttgggtgat ggatattact tacattccat gtaatgacgg
     2581 tcgcctctat ttgtccacct atattgactt agcaactcgt attctacgtt actatatggt
     2641 agattcacac atgaaaaaag agattgtcgt ccgtccatta caaatttatt aaggagaatt
     2701 gcctacggta attcattccg atagaggtag ccagcatcgg tcttttattt atcaagagct
     2761 gttgaacgac caccacatca cacattcagt gagccaaact gggactcctg ttgacaatgc
     2821 agtaattgaa gcgtttcatc gatcaatcaa atgagaatta atcgactcca acaaatataa
     2881 aagtaaaata gagatgaagg tgttaatcca agattattta gaagactact acccaaacaa
     2941 aagaatccat acaaaattta tgatgactcc ttgacaattt gaagcgaaga aaataaggga
     3001 tctataatat ctagtgttgg tgacgccttc tgttgccaat actttttctt ttttctaata
     3061 aacgcaaaca gacacctt
//
LOCUS       DBBGRF010000125         3038 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000125 DBBGRF010000000
VERSION     DBBGRF010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.130"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(26..961)
                     /gene="murB"
                     /locus_tag="ACIZD4_002969"
     CDS             complement(26..961)
                     /gene="murB"
                     /locus_tag="ACIZD4_002969"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGC5991807.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1034..1954)
                     /locus_tag="ACIZD4_002970"
     CDS             complement(1034..1954)
                     /locus_tag="ACIZD4_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC5991808.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2067..2819
                     /locus_tag="ACIZD4_002971"
     CDS             2067..2819
                     /locus_tag="ACIZD4_002971"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGC5991809.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
BASE COUNT          856 a          612 c          526 g         1044 t
ORIGIN      
        1 tacttatttt aagttccatt acttattaat tggctaaact tctgcttgtt tctgatattg
       61 cttgtttttc tccaatgatc cgcacttctg tttctaaaga cacatcaaat ttttctttga
      121 ttacttcttg gatgtgcgca atcaattcaa tataatctgt cgctgtcgca tgatcgatat
      181 tgacgatgaa tccagcatgt ttttcagaga cttgtgcacc gccccatttc aggccttgca
      241 atcctgcttg ttggatcagc tgacctgtat agtgtcctac tgggcgctta aagacacttc
      301 cgcatgaagg gtattctaat ggctgttttg attgacgcaa ttcggtcaac tcatccattc
      361 ttgctttgat tgcttcataa tcccctgttt gcaaactgaa tcgagcttcc aatacgatag
      421 cacgtaattc ttggacttta ctgtgacgat aagaaaatac catttcgtct tttgtcaaag
      481 ttttcaatgt tccatcttca agcaaaagat ccacttcagc aaaaacatct ttgatctctc
      541 cgccatacgc acctgcattc atataaaccg ctccaccgac acttcccggg atgccgcaag
      601 caaattcaaa tccagtcaat gattctgcca aagctgcata agtcgtatca atcagtgagg
      661 cacctgcttc cgcaatgacc atcgttcctt tgacatgaat ctgtttcatt tcagtcagca
      721 tgatgactac accgcgaatc ccgccatctt gaacgatcag attgcttgca tttcctaata
      781 ccatccaagg tatatcatgg attcggcaat aatcgatgat ttgctttact tcttcttgtt
      841 ttttcgggaa tgcaaggaca tcagctggtc cacctgtttt cgtaaacgta tagttcatca
      901 atggttcatc aaacaatata gtaatcgtgg ctaagctttc aactatttct tctttattca
      961 ctgaggattt tcctttcttt tctcaaacgt cctcattatt ctatcacgct taatacaatc
     1021 ttgccagtct tgttcaaagt tgatgacggt agtgatcttt aagcacttcc tcacataatt
     1081 catgacttct tacaacttct ttttgtttaa gcaattctgt ttccgattta cctaaacgga
     1141 tctgagaaaa gaaggcctct accattggct caaacccgcg tttgactagc gtgtttgtcc
     1201 agtcgccaaa ttctttcact ttttttccat cagcatcttg aatgacaagc tgggtcagat
     1261 cgtttacttc ataagtacca tttttacttg ttacttgata tttttctata ttagcgccac
     1321 ttgctaaatc catcgttaaa atagccgttt gattttgtgt ttctaattgt aaaatggcat
     1381 attccaaaaa ttcctttgtt tctcttatct ggtattttgt tctcaaaatg ggttcatcta
     1441 ataaatacac agctgtatca ataagatgta aaaacaaatc ataaaggacg aactctgtcg
     1501 tttcttttgc cgctattcga tttttttgca ggtggatcaa ccgcttatct gggatacgtt
     1561 tcaattcttc taccatagga gcaaagcgcc ggttgaaacc gatcatcaaa attatttggt
     1621 tcttatcagc taattcttgc aattcacgaa cttcatttag atggacactc agtggtttgt
     1681 caatataaac atggatacca ttttctagac attttttggc taattcataa tgtacttttg
     1741 ttgctgcgtg gatcatacat gcttcgattt tttcttctaa aagctcatcg atcgtttcat
     1801 atagatgttg gaacccgtac tctttttgaa ttctttcttt tgtttcttta tttcttgttg
     1861 caaaataaaa atcaagtgtt ccttgttttt tcgcataagt tggtaaatat gctttttctg
     1921 cgatattccc tacaccgatt acaccaatct tcatctactt tcctcctgga tcatttagtt
     1981 actttcatct tacaccattt tttactaaaa tgaggtacaa tagtatcgca aaggtaagga
     2041 aattaattcg aaggagtgtg cttttattga aatttatctc ttggaacgta aacgggcttc
     2101 gtgccatcgt aaataaaaat tttttagaag tttttcatga gttagacgcc gattttttct
     2161 gtctgcagga aacgaaactc caagcaggac aaattgattt agatcttcca ggttattatc
     2221 aatattggaa ttacgcggaa cgaaaaggct attccggcac agcgattttt gctaaaaaac
     2281 cagcattgaa tgccacttac ggaatgggta tcgatatcca tgatacagaa ggccgtctga
     2341 ttactttgga atattccgat ttctttcttg taacctgtta cacgccaaat tctcaaagcg
     2401 aattaaaacg tttagattac cgattagaat gggaagaagc cttttataat tatttggaaa
     2461 atctaaaaaa acaaaaacca gtcatcgtgt gtggggatct aaatgtcgct catcaaaaga
     2521 ttgatttgaa aaactggaaa acgaatcaaa aaaatgctgg attcactcca gaagaaagag
     2581 cggctctttc tcgactgttg gataacgggt ttatcgatac attccgttat ttttatccaa
     2641 cccaggaagg tgtctactct tggtggaact accgattcaa ttcaaggaaa aacaatgctg
     2701 gttggcggat cgattacttt ttgacgagca aagatttaga gccaggacta gctgatgcaa
     2761 agatccatac ggacattatg ggcagtgatc attgtccagt agaattagat ttgaaataaa
     2821 gaggttgtga aaaagtcgtt tagtttcgag tattaagaaa aattttgtga aaatggcttt
     2881 ccacattttg cataaatttg gcataatacc gagaaactgg cttttgaaca ctgtttatcg
     2941 agagattgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc
     3001 ctcatatttt tcgtttggtt gggcttatta ccgcagat
//
LOCUS       DBBGRF010000126         2932 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000126 DBBGRF010000000
VERSION     DBBGRF010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.131"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            88..984
                     /locus_tag="ACIZD4_002972"
     CDS             88..984
                     /locus_tag="ACIZD4_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HGC5991810.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIVHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
     gene            1076..1291
                     /locus_tag="ACIZD4_002973"
     CDS             1076..1291
                     /locus_tag="ACIZD4_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HGC5991811.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
     gene            1309..1581
                     /locus_tag="ACIZD4_002974"
     CDS             1309..1581
                     /locus_tag="ACIZD4_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HGC5991812.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILTKEKVA"
     gene            1583..2446
                     /locus_tag="ACIZD4_002975"
     CDS             1583..2446
                     /locus_tag="ACIZD4_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HGC5991813.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAISEETQGNVVIIDNDTFKQQHPNFDELVKLYEKDVVKYVTPYSNRMTEAI
                     ISRLRDKGYNLVIEGTGRTTDVPIQTATMLQAKDYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQPPTP
                     PIPKTPKLPGI"
BASE COUNT         1163 a          464 c          510 g          795 t
ORIGIN      
        1 aaagagggct tttatatatt aatcacaaat cacttatcac aaatcacaag tgattaatca
       61 caaatcactt gtgatttgtg attcttaatg atacaatatt actatacaaa aaaagaatgg
      121 ggcgtagtta tggagaagga aaaactaaaa atacttgaag aattaagacg tattttaaac
      181 aataaaaatg aagcaattat tatcttgaat aattacttta aaggtggtgt tggaaagtcc
      241 aaattatcga ctatgtttgc ttacttgaca gacaaattga atttaaaagt tttaatgatc
      301 gataaggact tacaggcaac attgacaaaa gacttagcaa aaacttttga ggtagaattg
      361 ccacgtgtca atttttatga aggcttgaaa aatggaaact tggcttcttc tattgttcat
      421 ttgactgata atttagactt gatccctggc acgtttgatt tgatgttact gccaaaatta
      481 actcgctcat ggacttttga aaatgaaagt agattgcttg ctactctttt agcaccttta
      541 aaaagtgact atgatctcat tattattgat actgtaccaa cgccaagcgt ttatacaaat
      601 aatgcaatcg tggcgagtga ttacgttatg atccctttac aagcagaaga agaaagtaca
      661 aacaacattc aaaactatat ttcctatttg attgatttac aagaacaatt taaccctgga
      721 ctagatatga tcggttttgt tccttattta gttgatacgg acagcgcaac gataaaatca
      781 aacctggaag aactgtacaa gcaacataaa gaagataact tggttttcca aaatattatc
      841 aagcgaagta ataaagtaag tacctggtct aaaaatggaa ttacagaaca caaaggctat
      901 gacaaaaaag ttttatccat gtatgagaac gtattttttg aaatgcttga gcgaattatt
      961 caattagaaa acgaaaaaga atagaatcac aaatcacaag tgattaatca caaatcactt
     1021 gtgatttgtg attgttgatg ataaaataag aataagaaga aatagaaaga agtgagtgat
     1081 tgtgggaaat ttaggcgcac aaaaagcaaa acgaaatgat acaccaatca gtgcaaaaaa
     1141 agatataatg ggagataaga cggttcgtgt tcgtgctgac ttacaccata ttataaaaat
     1201 tgaaacagca aaaaatggcg gaaacgtaaa agaagttatg gatcaagcct tagaagaata
     1261 tatacggaaa tatttacctg ataaacttta aaaaggagtg aaaatgaaat ggcagttacg
     1321 tatgaaaaaa catttgaaat agagatcatt aacgaattat cggcaagcgt ttataatcga
     1381 gtattaaact atgttttgaa ccatgaacta gatactaaaa atactcgttt actagaagtg
     1441 aatcttttaa atcaattaga agtggcacaa gaagttgatt tatttcaaca accatttgaa
     1501 gaattacaag ctattcatga gtattggcgg tcaatgaatc aatattcaaa acaaattttg
     1561 acaaaagaga aagtggctta acatggcgaa tattactgac ttcaccgaaa agcaatttga
     1621 agatcgttta gaaaagaatg ttgaacgact aactaaaaat agactagcgg ttgaatcgcc
     1681 aaccgctttt ttacttggtg ggcaaccagg atcaggtaaa actagtttgc gatcggcaat
     1741 ttccgaagag acacaaggaa atgttgttat cattgataat gatacgttca aacaacagca
     1801 ccctaatttt gatgaactag tgaaacttta tgaaaaagac gtagtaaaat acgttacccc
     1861 ttattctaat cgcatgacag aagcgatcat aagccgtttg agagataaag ggtataattt
     1921 agtgattgaa ggtacaggac gaacaacaga cgttcctatt caaaccgcaa caatgcttca
     1981 agccaaagat tatgaaacaa aaatgtatgt catggcagta cctaaaatca actcatattt
     2041 aggaacaatt gaacggtatg aaactatgta tgcagatgat ccaatgacag ccagggcaac
     2101 accaaaacaa gcgcatgata ttgttgtcaa aaacttaccg accaatttag aaacccttca
     2161 taaaacgggc ttatttagcg atataaggct ttacaataga gaaggagtga aactctattc
     2221 aagcttagaa acgccttcca ttagtccgaa agagacctta gaaagagaat taaatcgtaa
     2281 agtatcaggg aaagaaattc aaccgacttt ggagagaata gagcaaaaaa tggttcaaaa
     2341 tcaacaccaa gaaacccctg aatttaaagc aattcaacaa aaaatggaaa gcttgcagcc
     2401 acctacacca ccaataccca aaacacctaa acttccaggg atttaaacct taaaaaagta
     2461 aaagagtagt taccaaaaaa cggtaactac tcttttttta taaaaacatt tcctcatttt
     2521 ttaaaagctg atcgagaaat aaagcacaca actgtattct ttcttttttc agttggtaca
     2581 ttttgcagtc tgtaacgtgc catttactgt ttgttacctt aacatatcca gtcgaaaaca
     2641 caagggtata taaacgagca agctcgccct tgtgttttct ttgtgtctat gttgcgttct
     2701 cgtcacagca aacgacacga acacactggc gaaaatgaac caacaaaacg aaaaaagaaa
     2761 ggagcgtaca ctgtaattta tttctagctt ttaaaacatg aggaaaacag cttcacttcc
     2821 tcaaacgcct aacaaaaatg gttgtcaaaa aactaaaaat caaaaaaaga aaagaggaaa
     2881 agaaaatgga aaaaacaaaa aaattacaat tagaagattt tacagaaaat gg
//
LOCUS       DBBGRF010000127         2833 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000127 DBBGRF010000000
VERSION     DBBGRF010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.132"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..1394
                     /locus_tag="ACIZD4_002976"
     CDS             <1..1394
                     /locus_tag="ACIZD4_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HGC5991814.1"
                     /translation="KVEVGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYE
                     GVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPAL
                     PEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPE
                     GQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSD
                     EVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVD
                     VSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNA
                     EVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNK
                     KDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTL
                     GLLGYKNRKKENE"
     gene            1528..>2833
                     /locus_tag="ACIZD4_002977"
     CDS             1528..>2833
                     /locus_tag="ACIZD4_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGC5991815.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNF"
BASE COUNT         1110 a          387 c          554 g          782 t
ORIGIN      
        1 aaaaagtaga agttgggggc acagtagatc taacagataa tgttactaac ttgccagcgt
       61 taccagaagg aacaacagta acagatgtta ctcccggcgg tacaattgat accaacacac
      121 caggtaatta cgaaggtgtc attgaagtaa cgtatccaga cggtacgaaa gatacggtga
      181 aagttccagt agaagtgaca gacaatcgtt ctgacgccga taaatatgaa ccaacagtag
      241 aaggcgaaaa agtagaaatt ggaggcacag tagatttaac agataatgtt actaacttgc
      301 cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca attgatacca
      361 acacaccagg caattatgaa ggtgtcattg aagtaacgta tccagacggt acgaaagata
      421 cggtgaaagt tccagtagaa gtgacagaca atcgttctaa tgcagataaa tacaatcctg
      481 aaggacaaaa agtgactaca gacttaaata aagagccaga tgcatctgag ggaattaaga
      541 acaaagaaga tttaccaaaa ggaactactt atgcttggaa agagaaagta gatgttagca
      601 cagctggaaa taaaaaaggt actattgtag tgacatatcc agatggatca tctgatgaag
      661 ttgaagtaga cgttacagtg acagatactc gttccgatgc agataaatat aatcctgaag
      721 gacaaaaagt gactacagac ttaaataaag agccagatgc atctgaggga attaagaaca
      781 aagaagatct accaaaagga actacttata cttggaaaga aaaagtagat gttagtacag
      841 ctggaaacaa aaaaggtact gtagtagtaa catatccaga tggatctaaa gaagaagtag
      901 aagttactat ttctgtagta gataaaaaag caccgaataa acctcaagtt gatcctatta
      961 cagagggtga ccaaattgtt actggtaaaa ctgaaccaaa tgcagaggtg acagttacat
     1021 taccagacgg aagtcaacac catgggacag ctgataaaaa tggtaatttt acagttaaag
     1081 ttcctaaatt agaggcaggg acaaaagtga tagtaactgc aactgatgaa tctggtaata
     1141 ctagtgaacc tactaatgta gttgtttctt ccaacaaaaa agacagtgga aaaaacggta
     1201 gtaaaggtag taagactgac aatcaaggta gcaacagcaa tcaagacaaa aatagaggca
     1261 aaagccagtc ctcaaaagtt tttcctaaga cgggagagag tgacagtaat atctttacta
     1321 ttagcggtgg tttaatactg ttaggaacgt taggattatt agggtataaa aatcgaaaaa
     1381 aagagaatga atagaaaatc aatttcttaa gtcttctctg agaagaggaa gaatcttttt
     1441 cttcctcttt ttgctttttt atgatgggaa ataagtgtta gttaaagatg aatatacttt
     1501 ttatagaaag gaaaagaatg taattaagtg gaaaaaatag taattattgg ttcaaaccat
     1561 tcagggctag ccgcagctcg atttctaaac ttaagcgatt caaattatga agttattcta
     1621 atcgataaaa aatcagaaat tagttacttg gaatgtggga catcgttatt tataaaagga
     1681 gaagtaagta atttagaaga tcttttttat caaaatagaa tgacactaaa ttctgagata
     1741 aaaaagttat ttctagagac agaagttgac aaaattgata ttcaaaataa aaagattagt
     1801 tgtgtaaaaa aagatggtac aagattctct caagaatatg acaaagttat attagctaca
     1861 ggttcaaagc aaattatgct agatataccg gggaataatt tagctaatat tttttcgata
     1921 aagaattttc caaatgcaaa agagattttt aaagctttgg atgatagtac tattaaaaaa
     1981 gtaggaatta ttggagcagg atatattgga gttgaaattg ctgaagccat aagaaaaaga
     2041 gggaaagaag tatatctttt cgatgttgca gatagagtgt tgtcgactta ttacgaccgt
     2101 agtttttcag ataaagttga agaaatacta tcaaaaaatg gaatacatct ttgtctatca
     2161 gaaagtccta aaaaatattt aggaagaaaa aagattgaaa aaatagtcac tacaagtggt
     2221 acccaatact ctatggatat ggtcgtacaa gctataggat ttctatctaa tagtccaatt
     2281 ggggaaaagg aactcttgag agatgttagt ggagcatatc taactaatga ataccagcaa
     2341 acaaatataa aagatatata tgctattggg gattgtgcta caactttttt tacgtccatt
     2401 aatagaagta gtgttgattt ttctatttct aatgctctaa gaacagctta tattgcaact
     2461 caacatatta acaatcaaga ttttacacct tctggttccc aatttacaaa tggcttttct
     2521 atatttaatt acaattttta cgcagcaggt ttgaatttaa aaacagcacg attattaagt
     2581 gagtctatag attatataga aatagaagat ttcattagac ctgctttttt gagaaaaaat
     2641 agtcgtgtaa aattaagaat tagctttgaa aaaaatacaa agagaatagt aggtgtacaa
     2701 ctttgtagtc aagaagattt atctggacta ttatcaatgt tttctcttgc tatagaagaa
     2761 caaattacat tagacaaatt gaaaatgtta gattatttat ttcatcctag ttttagccaa
     2821 ccctataatt tta
//
LOCUS       DBBGRF010000128         2667 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000128 DBBGRF010000000
VERSION     DBBGRF010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.134"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            751..2577
                     /gene="ltrA"
                     /locus_tag="ACIZD4_002978"
     CDS             751..2577
                     /gene="ltrA"
                     /locus_tag="ACIZD4_002978"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGC5991816.1"
                     /translation="MLKKNKLRYNEYYDMQHIYDELYAQSKNGNNFYKLLEIIGSEQN
                     ICLAYRNLKSNSGSKTAGTDGMTIDDIKQLSNAEIVATVRESLSNYRPKSVRRVFIPK
                     AGSDKMRPLGIPCIWDRLVQQCILQVLEPICEPKFHNHSYGFRANRSAHHAVSRVTTL
                     INLSKYHYCVDVDIKGFFDNVNHGKLLKQIWTLGIRDKRLICIISKMLKAEIDGEGVP
                     EKGTPQGGLLSPLLSLIVLNELDWWVSSQWETFQPKNRSKNGWLQYAKKYTKLKSGFI
                     VRYADDFKIMCSTYGEAQRFYHSTVDFLNKRLKLEISPEKSKVVNLKKNSSDFLGFKI
                     KVIPKGRTKHGYVAKTDMNQKALKKAKTNLKLKVKDIARHTTGFNISRYNLTVIGMQN
                     YYCIATNVYNNLTEVSYALLPTIRIRLRNIAKSVPFESTSSEFQSRTKGIRPKTKIVM
                     IADNPLLPIQGVQHKNPMNFSQDICNFTKQGRNKVHEDVVVVTKEEIRALLENENPAD
                     SVEFNDNRISAYIAQQGNCYVMNRRGTPSTLICIHKSDKGDNLDRYSNLAFVEIPIAK
                     AILTESADEAKSLLKGYVLNSQQKKKLNRIRTNYGYQTITGK"
BASE COUNT          955 a          466 c          593 g          653 t
ORIGIN      
        1 aaagggggtg cgaaacgttc ctacttgaaa agagtaggca cagcacttca ttaaatcaat
       61 atttaatgtg tgttggagaa ctaaacacac gaatagtcga atgacggggt aacgccctga
      121 aaggctactt taatactctg actggcagaa acttgagtaa acaaggctct gtcagaagct
      181 cggtgaagtc ggcagacaga caccgtaaca gataatgctg acgaaagatt cccagaggtg
      241 ggcgttgtgt cctatatgcc ggaagtctat aaaatatcta tggttagaat gtagatgaga
      301 ggtctactga cgaatccttg aatgtacagg tctatatcgg ggctggatag aaatgtccag
      361 tgacacaaac agtgtcgcta ctgtgggtga gtaagactcc gcatttatga aaatccatat
      421 aacgttaaag gcgttatcaa ggtagcaggc ttatagagga aacctaagga tatatgtaca
      481 gatagtgtgt ttggaacgtt gaaagctgac aacatggaga ttttactgtc tgtgaagtgt
      541 tcacatcaga aagttattgt gagattagca atgatataag gtgtgttaat gtcagtgaga
      601 gtggtggcac agtacctatg aaaccgtgat aacaagcggt ggagggatag ccactagtca
      661 tatgaagaat agaattacta agaaaaatgg tatgggttcg agtaagacta agagatgtac
      721 ttgctcctgc aaacaaggag ggtacagacc atgctaaaga aaaacaagct ccgctataac
      781 gagtattatg atatgcaaca tatttatgac gagttatacg cacagagcaa gaacggtaat
      841 aacttttata agttacttga aattattggt tcggaacaaa atatttgttt agcttaccgt
      901 aatctgaaat caaacagtgg cagtaaaacg gctggaacgg atggaatgac gatagacgat
      961 ataaaacaac tcagcaatgc tgagattgtt gctaccgttc gggaaagcct tagcaactac
     1021 cgccccaaat cagtcagacg tgttttcatt ccaaaagctg ggagcgataa aatgcgtcca
     1081 ttggggattc cgtgtatctg ggacaggctg gtacaacaat gtatcctgca agtcctagag
     1141 ccgatatgcg aaccaaagtt ccataatcat tcctatggat tccgtgcgaa tcgaagtgcc
     1201 caccatgcag tcagcagagt aacgacactg ataaatttat caaaatatca ttactgtgtt
     1261 gacgtagaca ttaaaggatt tttcgataat gtcaatcatg gaaaactatt aaaacaaatc
     1321 tggacacttg gtattcggga taaaagattg atttgcatta tcagcaaaat gctgaaagcc
     1381 gaaattgacg gcgagggtgt cccagaaaaa ggaacgccac aaggcggtct gttaagtcca
     1441 ctgctctccc tcatagtcct taatgaatta gactggtggg taagcagtca gtgggaaaca
     1501 ttccagccga agaaccgcag taaaaatggg tggcttcaat acgcaaagaa atataccaaa
     1561 ctgaaaagcg gttttattgt acgttacgct gatgatttta aaatcatgtg ttcaacctat
     1621 ggagaagcac aaagatttta ccacagtacc gtagattttc ttaataaaag gctgaaatta
     1681 gaaatcagtc cagagaaatc aaaggtagta aatctgaaga aaaattcatc agattttctg
     1741 gggttcaaaa tcaaagtcat tccaaaagga agaacgaaac acggttatgt tgccaaaaca
     1801 gatatgaacc aaaaagcatt aaagaaagcg aaaacaaatc taaagttaaa ggtaaaagat
     1861 atagccagac atacgactgg cttcaatatc agcagatata atctgacagt tatcggtatg
     1921 cagaattact actgcatagc aactaacgta tataacaacc tgacagaagt aagttacgct
     1981 ctcttaccga ccatacgaat ccgtttaagg aacattgcaa aatcagttcc atttgaaagt
     2041 acaagttcag aatttcagag caggacaaaa ggaatcagac caaaaacaaa aatagtgatg
     2101 attgcggata atccgctatt gccgattcaa ggagtacaac acaaaaatcc tatgaatttc
     2161 tcgcaagata tttgtaattt tacaaagcaa gggagaaaca aggtgcatga ggacgttgta
     2221 gttgtaacaa aagaagaaat ccgagcgttg ttggaaaatg aaaaccctgc cgatagcgta
     2281 gagtttaacg acaatcgtat ttcggcatat atcgcacaac aaggcaactg ctatgtaatg
     2341 aatcgtcgag gaactccgtc cactctgata tgtattcaca aatcagacaa aggagataac
     2401 cttgacagat attctaatct ggcatttgtg gaaattccca ttgcaaaggc aatcctaaca
     2461 gaatcagcag acgaagcaaa atcactgtta aaaggttatg ttcttaatag tcagcagaag
     2521 aaaaaactga acagaatacg gacgaattac ggataccaga caataactgg gaaataactt
     2581 ataaatctat ttggatatga tggaacgccg tatgaagcga aagtttcatg tacggtgtga
     2641 agcgggggaa aacttggaga taacatc
//
LOCUS       DBBGRF010000129         2483 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000129 DBBGRF010000000
VERSION     DBBGRF010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.136"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..300)
                     /locus_tag="ACIZD4_002979"
     CDS             complement(<1..300)
                     /locus_tag="ACIZD4_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HGC5991817.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACIZD4_002980"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACIZD4_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACIZD4_002981"
     CDS             complement(1014..1304)
                     /locus_tag="ACIZD4_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991818.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2203)
                     /locus_tag="ACIZD4_002982"
                     /pseudo
     CDS             complement(1512..2203)
                     /locus_tag="ACIZD4_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          734 a          458 c          348 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgatttct acatttgttt
     1681 tttcttgtgt cagtgttgcg atttgttgat tcaaaccatt tacagtattt tgtaattctg
     1741 aaagttttgc ttgtgcttct tgtagtcttg ctgtccaatc tgcattcaga tgattgattt
     1801 catcattttt ttggttgatc tcatctagtt tgacattgat ttcattttgt ttgctttgta
     1861 gttgtgcatc cttgctgact aattgacttt ctaagttttg tttttctgct gccgattgat
     1921 ttttttggtt ttctaattca tttacttttg tttggtattc ttggacatct gcctttgaat
     1981 cttgcaatgt ctgttctttt tgtgctagtc gagcggtaag atctgtaatc gcttgctctt
     2041 tatctgtcaa tgtatgatca agctgtgtca gattctcatt gattgtatca atatctgtct
     2101 ctccacccca caaaataatt tcatttgcgt accgcgtgcc tgtgtagcca attagacata
     2161 gaaatgcaac gacaatccca ccagtaataa atttcttttt catttgcata gctccttaat
     2221 ccaatacttt tacatgctaa aagtaagtga tctcaaacac aatgtcaagc gtttttaaat
     2281 tacatatgta attttaatat aaatactatc aaatactcat ttaatcctcc ttttttatct
     2341 atttaaaaaa tcttttttat agagaaaaat gcaggttaat actttcttaa ataaatattt
     2401 atggtgaaca aaaacaaaaa agcaagtttt attaaacgta acccttttca tttcatagat
     2461 tactgtattt attacaaaaa acg
//
LOCUS       DBBGRF010000130         2458 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000130 DBBGRF010000000
VERSION     DBBGRF010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.137"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(77..397)
                     /locus_tag="ACIZD4_002983"
     CDS             complement(77..397)
                     /locus_tag="ACIZD4_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5991819.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENK"
     gene            697..837
                     /locus_tag="ACIZD4_002984"
     CDS             697..837
                     /locus_tag="ACIZD4_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991820.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            1135..1392
                     /locus_tag="ACIZD4_002985"
     CDS             1135..1392
                     /locus_tag="ACIZD4_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HGC5991821.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(1363..1671)
                     /locus_tag="ACIZD4_002986"
     CDS             complement(1363..1671)
                     /locus_tag="ACIZD4_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991822.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            1749..>2458
                     /locus_tag="ACIZD4_002987"
     CDS             1749..>2458
                     /locus_tag="ACIZD4_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HGC5991823.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEG"
BASE COUNT          894 a          433 c          414 g          717 t
ORIGIN      
        1 tccatataaa ctactttcaa attgtattcg ctcaacattt ctttcaattt caaatacata
       61 taaaccatca ctccaactat ttgttttctt ctaaagcttt agcaattgca atcgctttac
      121 gcattgtctc cttagatatt tcttttccgt caaaagagaa tacagtatcg tcttctgata
      181 aatccacatg tttaggggtt tctctttctt ctctacctag aagatagtct acagagactc
      241 caaagtaatc agctaaccga gctaactcaa tagaattagg agtttgtctt ttccaacttc
      301 ctaaatatcc attcgaatac ccgaaattca tttcgagctg tctaatggat aatccttttt
      361 cttttgctaa ctcctttatt atttcgtaag tattcattga taaatcaacc tttctgaatg
      421 cttacaaaaa aagtttagat aaataatgta aaaatagttg acttatatac attattaatc
      481 tatactatgt tttgtaaaca agtttaacaa ctaaaaagac aacaaaaaat actattgatt
      541 aataaatgcc aaccgccaag aaagcttttt aaatcaaagt ttatatgtct tatttaacta
      601 tgcatttagt atagattatt aatctaataa agtcaacgca gttttttaaa aagttgttaa
      661 atttgtttac gaatataaaa gaaaggagag aagaatatgg aaaaaacagt ctcggcaaaa
      721 atcgaagatt tgaaattaga catactgaaa caagcaaaag tggcgatgga acacgcggta
      781 gataaagaag actctgccat ggttgcagcc atagcagaga ttttagctca cgtttagtca
      841 tcgtttttac ggtcttctgg aagctgacca tagataacag cataatgaat atctaaataa
      901 gcttgaacaa tttcttttgg cgaaattgat tcgcctttag tagatacttg tgattcgtga
      961 tttagccatg caacaactaa atccgcagcg atttcaaacg gcgttacact ttgtgtcagt
     1021 tgccataaag aatttcacaa tatgtatggt cgtggtaata ataccaaaga gcaatttgag
     1081 gaatttatgg aaattaaaaa atacaaaaaa tcatttatta aaggaggcta aacaatgaac
     1141 aaggaaatga gccaaacaat caaggtacaa aaaatgatag atgatctaac acatggaatt
     1201 gatagccaag ccgataaaat catcaaggaa ttgcaaggac aaaaagttaa ggatgcaaaa
     1261 atgcttctca agactatcaa ctttgaaatg aatccaacaa aaagaaagct cgccgatgtg
     1321 ttggaagaaa agttggcttc cgctatcaac gagcaagaat tactatttga aaccgatact
     1381 tttaacagct gatgttttat agatgacagt ttcatccgaa tctatatcat cgccgagaga
     1441 aaagaatgtt gcttttgaca aaaagccgat aagacctaca agcggtcttg atgttgcaag
     1501 agtagatacc ccaatatcac cttgcaaggt attcacgtaa atttgagaag aatagaacat
     1561 tccatctttt tcttcgatat ttgacgcatc atcgtatcca acgaccaaag tatcggcaaa
     1621 tattttgatt ttttctccat caagcatagt aattacaaat tctggtttca taaattttca
     1681 cctccttaac aattatttca gcctgtcaca ctgataagga aattatacca aagaaaggaa
     1741 tgagaaatat gaatacacca caaattttta atttcgagca aaacgaagtt cgaactattt
     1801 tagtaaatga tgaaccatat tttgtaggaa aagatgtagc agacgttcta ggatattcga
     1861 atccgcaaaa agctattcga gatcatgtgg acttggagga taagacgcag aacgattcgt
     1921 tcaccgtcaa tggaacagca gttgttttga ttaacgagtc aggcctttac agtttaatct
     1981 taaaatcaaa acttccctct gccaaaaaat ttaaacgttg ggtaacgagt gaagtccttc
     2041 caacaattag aaaaacaggt agctattcaa acgtacctca aagttttgca caagcattgc
     2101 gtttagcagc ggatttagaa gaaaagaacc aattactcga acaacaaatt gccgagtacg
     2161 aaccaaagat tagctactta gatacgattc tttcatcgac agatacggta gctacttctc
     2221 aaattgcagc tgattacgga atgtcggcaa ttgctctaaa caaattgcta aacgagttag
     2281 gtgttcagca taaagttagc ggacaatgga tactttaccg aaaacatatg aaccaaggat
     2341 acacaaaatc gcacacaagt gagataccga aagccgatgg cggcactaaa gttgtaatga
     2401 ataccaaatg gacacagaaa gggcgagtgt ttatttacaa cttattaatc gcagaggg
//
LOCUS       DBBGRF010000131         2291 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000131 DBBGRF010000000
VERSION     DBBGRF010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.138"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..2148
                     /locus_tag="ACIZD4_002988"
     CDS             <1..2148
                     /locus_tag="ACIZD4_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HGC5991824.1"
                     /translation="KDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFFII
                     FTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKANQ
                     AITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKRLS
                     AKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGVTD
                     QELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLAKG
                     YSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSMNA
                     EFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEITE
                     NALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRSGQ
                     VALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFGLG
                     TTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQYA
                     STVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGFHQ
                     VVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEIAI
                     SVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          782 a          413 c          509 g          587 t
ORIGIN      
        1 aaagatttta tgaaaaaaat attaaatact tcttggttag aaaaaataag aaaaggtgca
       61 caagaaccta agaacaaaac gtttcgccgg tcccatgttc cttttcgctt aaattttctt
      121 tttttcatta tatttacgtt atttgttgcg ttgattgcta gattgggtta tttgcagatc
      181 gtgaacggcg aagagatgga ggcgcgagtg aagtctactt ctacgattac ggtccaagaa
      241 agtactcctc gcggaatgat ctacgactcc acaggaaaag ctttagttac gaataaagcg
      301 aatcaggcca tcacatatac gagaggaaca caagttacgg ctaaagattt gcttgaaatc
      361 gcaacgaagc tgaactcgct gatcgatgtt ccggtagatg aaaatctgac agatagagat
      421 aaaaaagatt tttggctggc tgatcccaaa catttgaaag aagccacaaa aagactttcg
      481 gcaaaagaaa agcaattagg gaacagcgaa caatatagtg cgatggtcaa taaagtcaca
      541 gctgatgaga ttaatttaaa cgaggagcaa ttaaaaattg ctaccatctt taaacggatg
      601 aatagtgcat atgaattaaa cactgtctat atcaaaaact ctggtgttac tgatcaagag
      661 ttagctgttg tggcagaacg cgcttctgaa cttccaggag tttcgactgg cacagactgg
      721 acacgagaat ataatgcagc aagttcactg aaaagtattc ttggcagtgt gacgactgaa
      781 aagcaaggac ttccagcaga tgaagcagag aaatacctag caaaaggtta ttctcggaat
      841 gaccgtgtag gacaaagtta tttggaaaaa caatatgaag atgtcctgca aggaaccaaa
      901 acccaatatg aagtttccct tgataatgaa ggaaatgttt cgaatcaaaa agaaatcttc
      961 tctggggaaa aaggttctaa tttaatgtta tctatgaatg cagaattcca atcaaaagta
     1021 gaagaaattt tgaaaaggaa ttatcaaaca ttgatcaaca acggcaaagc acagtattcg
     1081 cctggtgctt atgcagtggc tatgaatcct cagacaggag aagtgctagc aatgactggt
     1141 ttcagtcatg aacaaggttc caaagaaatc accgagaatg ctttaggcac gattactagc
     1201 gcctttgatc cagggtctgt agtcaaggct ggtactttga cagcaggctg ggcaagtaac
     1261 gcgatcagcg gaaatcaagt tttgattgat gagccgattc gtctgcaagg tgcttcagaa
     1321 aaaagctctg tctttaatcg aagcggacaa gttgctcttg atgcagtcaa agcatcggaa
     1381 ttgtcttcta atacgtatat gatcaaagtg gcgttaaaga tgttaggact agactataca
     1441 cctggaatgg gactacctag tttagatgaa gaagctaaag cttatcagca attgagagac
     1501 tctttcaaag agtttggtct tggtacaacg actgggatcg atttgccgaa tgaatctcct
     1561 gggatctcac gttctgttga ttatatgaag aagttcaatg cggataatgg caaagaatgg
     1621 tatgctccag gtaactttac cgatttggca tttggacagt ttgacacata tacaccaatc
     1681 caattagctc aatatgcttc aacagtcgct aatggcggga aacgagtaca gccgcaccta
     1741 gtcaaagcga tctatggcaa tgacgaaaat ggaaacttgg gtgaagtgaa gaaagaaatt
     1801 ggcacaacag tagaaaatac ggtcaatatt tctgcagaaa atatggcgat cctccgtgaa
     1861 ggattccacc aagttgtcca tggtaccgat ccttacacaa cagccaaacc attagccagt
     1921 gcgaaaatgg acctttccgc aaaaacaggg actgcagaaa cggttgcgga aggtcatcca
     1981 gatattgcga cagtcaatag taatatcgtg gcatacggac caacagacaa tccggaaatt
     2041 gccatcagtg ttgtcttgcc gaacttatta gacgaacaag accacataaa cttgacgatt
     2101 gctaaagaaa taatggacgc gtattatgat atgttcatgg caaaataaaa aagaggtcgt
     2161 gaaaaagccg cttagtttcg agtatgaaga aaaattttgt gaaaatagct tctcacattt
     2221 ttgcttaaat ttgacttcat accgagaaac tggcttttga acaccgttta ctcggcaaaa
     2281 aaggttgtga c
//
LOCUS       DBBGRF010000132         2270 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000132 DBBGRF010000000
VERSION     DBBGRF010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.139"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            191..445
                     /locus_tag="ACIZD4_002989"
     CDS             191..445
                     /locus_tag="ACIZD4_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGC5991825.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="ACIZD4_002990"
     CDS             446..763
                     /locus_tag="ACIZD4_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGC5991826.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="ACIZD4_002991"
     CDS             1322..2257
                     /locus_tag="ACIZD4_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991827.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          429 g          711 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag
//
LOCUS       DBBGRF010000133         2261 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000133 DBBGRF010000000
VERSION     DBBGRF010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.140"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            278..820
                     /locus_tag="ACIZD4_002992"
     CDS             278..820
                     /locus_tag="ACIZD4_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991828.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            976..1425
                     /locus_tag="ACIZD4_002993"
     CDS             976..1425
                     /locus_tag="ACIZD4_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HGC5991829.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMATIALDNEHPRI"
     gene            complement(1455..>2261)
                     /locus_tag="ACIZD4_002994"
     CDS             complement(1455..>2261)
                     /locus_tag="ACIZD4_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HGC5991830.1"
                     /translation="TYYYQAKPIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGL
                     QLSRRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQPLEAIVTDL
                     TYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDR
                     GKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQFETLAQLR
                     LELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          784 a          372 c          429 g          676 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcaaat tgatgaagca gatcccaaag ggctgcttca tcaatttttt
      121 cgtaagtgtc cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt
      181 gtaagaacaa ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa
      241 attatatttc atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa
      301 atgctattgt gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc
      361 atgcctatta cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga
      421 aaacaataaa ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa
      481 tgcaaatggc aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga
      541 atatgtttat gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat
      601 agctgataaa aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta
      661 tgctattttg acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat
      721 gggcgatgga tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt
      781 tgaaaaaaat acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa
      841 ataggagttt caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa
      901 agtaatcttc tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt
      961 cctaaaaatg gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac
     1021 aaagaatcgg ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt
     1081 acaagtaaag attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt
     1141 acagcttgtg taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag
     1201 ggtgtaaata tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa
     1261 gcaattgaaa agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg
     1321 ccagatggaa tggcaacact ttttttgaca aaaattataa ggtgttgtga atgctgcggt
     1381 gttatggcta cgattgccct tgacaatgag catcctcgga tctgattttc tccggcagaa
     1441 gcacaatcat tcaattacgc tgcctctcca gaggtatcag atccgcgctc attatcaagg
     1501 attcgcttcg ccaatctctg ttgtcgaatt tggatcggtg tttcatacgc caacgtgcca
     1561 tgtaagcgta gatagttcca ccaatgcaca taatcaaaca attctagacg tagctgtgcc
     1621 agtgtctcaa attggtattg atgcacgaat tctactttga cagatttata ggttgattcc
     1681 acaacggcat tatcatacgg acaacccttc ctactcaatg aacgagtaat tccaaaacca
     1741 ttcagaatct catgaatggt ttggttatca aattcctttc cccggtctgt atgaaaaagc
     1801 ttgacgtctg ttaaagaata cggtatccgt ccaaaggctt cttttaccaa tgaggcatct
     1861 ttcttctcac cacaggaata accaataatt tctcgattaa acaaatcaag tattaagcag
     1921 atataatgcc actttttccc cacgcgaaca taagtaagat ccgtaacgat ggcttccaat
     1981 ggctgttctt gtgtaaaggt ccgatctaat acattcgctg ttttcgcttc attacaagct
     2041 gttcgttgcc ctttaaaatg agcgatcgta taggtagatg tcaatccgcg gcgtttcatg
     2101 attcgaccga ttcggcgccg actgagttga agcccacgct ttgctaaaca cttcttcaat
     2161 tttcgggtac cgtaagcctt tcggtttcga ataaactctt cctgaacgat ctcttctaag
     2221 tcggactcat tttcgatcgg tttcgcttga taatagtagg t
//
LOCUS       DBBGRF010000134         2019 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000134 DBBGRF010000000
VERSION     DBBGRF010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.142"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            100..570
                     /locus_tag="ACIZD4_002995"
     CDS             100..570
                     /locus_tag="ACIZD4_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HGC5991831.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            792..1895
                     /locus_tag="ACIZD4_002996"
     CDS             792..1895
                     /locus_tag="ACIZD4_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HGC5991832.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          686 a          328 c          460 g          545 t
ORIGIN      
        1 gaatctctga agaataaatc acgtgatcgt gacgataaaa tacacttacg tcaggtgata
       61 aaaaatacat aagtagaaaa ctaagaggag gaacagaaaa tgaaagaagt tcaattgatc
      121 agaaaaagcg aactatcaga aggtggttgc aatgcatgcg gcgtagtaga agcaacaagc
      181 tatacattaa agcttggtgc caacaaagcg ataatctctg agttgacagt aggcggtctt
      241 gtggacagtc tggcgcttgc tgaaggtttt attggagaag atatttatga gatgttttca
      301 gaaatccgtc agttaaaaaa aggggaaaac tgcatagagg ttcatcatga gagcccgaat
      361 gtgagattca aacgtggtga taatgagatg atcttcaata atcatgtgtc cgatcacacc
      421 gagctatatg gaatcgtgaa tcaaatacta actgagcttt ttggattggg accttatgcg
      481 ttcaaggaag aaaacggtaa tccaaaatta aacgaagaat ggcaagaaac gattgaaata
      541 caaagaaaca acccgcactt atttcaatag gcatccacag tatttcgtaa aagggacttt
      601 gacacgactt ttgtcaaaat cccatcgttt tttatctatt tgtgttctaa acatttcttt
      661 cagagtagta acaactggaa tgactgaaat gtaaacagat tatttgcctg tatcaatacg
      721 gaagagtaat ataaagtgtg taaacgctat catattattc attcaatttt ttatagaggg
      781 aaggcattga aatggaaaaa acgtatcaag caggtacaaa tgaaggaata gtggatttta
      841 tcaatatgga agatttagaa atagccgctt cacaagtgat tccagctggt ggttatggtt
      901 acatcagcag tggtgctggc gacttattta cttatcaaga aaatgaacgg gcattcaatc
      961 atcagctgat tattcctcat gtattaagag atgtagaatt acccgataca actacacatt
     1021 ttgacaaaga aacgctgact gcaccaatca tcatggcacc agttgctgct catggcttag
     1081 ctcatgtgaa ggcggagaaa gcttctgcaa aaggtgtagc agattttggg acgatctata
     1141 cagcaagttc ttacgcttct tgtacattag aagagataag agaagcaggc ggggagaaag
     1201 caccgcaatg gtttcaattt tatatgagca aagatgatgg gatcaatttg gatattcttg
     1261 aagtggccaa gcgtaatgga gcaaaagcaa tcgtattgac agcggatgca acagttggcg
     1321 gaaaccgtga aacagaccgc agaaatgggt ttaccttccc actgccaatg ccgatcgttc
     1381 aggcttatca atcaggagta ggccaaacga tggatgctgt gtacaaatct tccaaacaga
     1441 agcttagtcc aaaagatgta gaatttattg ctgctcattc tgatttgcca gtctatgtga
     1501 aaggtgtcca gtcagaagaa gatgtctatc gttcattaga atctggtgct ggcggaatct
     1561 gggtatctaa tcatggtggc cgtcaactag atggtggtcc agcagcgttt gattcgttgc
     1621 aatatgtggc agaagcagta gataaacgtg taccaatcgt gtttgacagc ggtgtacgac
     1681 gcggacagca tgttttcaaa gcaatcgcat caggtgcaga tcttgttgct attggcagac
     1741 ccgttattta tggattgtct ttaggaggaa gtacaggagt ccatcaagtg tttgatttct
     1801 ttaaaacaga attggaaatg gtcatgcaat tagctggaac acaaacagta gaagatatca
     1861 aaaaaataaa attgcgtgag aatcgtttta tttaagaaac aaatgacgaa aaaaatagga
     1921 gtgcggcaga tgatgccgta ctcctatttt tatagttcaa ggatgtcact aatagaataa
     1981 tttgaaacga aaaaataaaa ttgaaatatt ttttcatac
//
LOCUS       DBBGRF010000135         1979 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000135 DBBGRF010000000
VERSION     DBBGRF010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.143"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(346..528)
                     /locus_tag="ACIZD4_002997"
                     /pseudo
     CDS             complement(346..528)
                     /locus_tag="ACIZD4_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(728..1744)
                     /locus_tag="ACIZD4_002998"
     CDS             complement(728..1744)
                     /locus_tag="ACIZD4_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC5991833.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          556 a          460 c          310 g          653 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaacg ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaacgct ctccgaggga tttcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt catgcaaaat attcgcttat
      661 cgtgaattta cgtcactaaa cattgacgca aatccactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DBBGRF010000136         1947 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000136 DBBGRF010000000
VERSION     DBBGRF010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.144"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            181..483
                     /locus_tag="ACIZD4_002999"
     CDS             181..483
                     /locus_tag="ACIZD4_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC5991834.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(999..1072)
                     /locus_tag="ACIZD4_003000"
     tRNA            complement(999..1072)
                     /locus_tag="ACIZD4_003000"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1036..1038),aa:Ile,seq:cat)
     gene            complement(1627..1941)
                     /locus_tag="ACIZD4_003001"
     CDS             complement(1627..1941)
                     /locus_tag="ACIZD4_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991835.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          708 a          289 c          301 g          649 t
ORIGIN      
        1 ttttataagg gtttgagcat tttttatttt cgcagatttt cgttaaatga atgaaaatgg
       61 cattcaaaat agcattcaaa aagaacactt tttaatatat atgttccatc catattatca
      121 atgatattcc tactttacaa aaagaacatt agttcgtata ctctttttga ggtgaacatt
      181 atgttgatgg aaggaaaaac acaattatgg tttaaatttg atccttcgaa tagatttgtc
      241 aaagattttt ataaggtgtg ggattcagaa gttttctttt tagcaatcga agatagctta
      301 ttaatcaatc tctattactc taataagaac tactttaaaa ttccggcaac aaaaaccaga
      361 atgaagaaag atgtgtattt tttgtttgat atcgtgactg atgtgccaga cgcacggagc
      421 gatcatcggc gttatgacta tttgaagtat actttcgttg atccagaaag gtataaagat
      481 taaagtaggc tacctaaaaa aggtagcccg gaacggattt tatcaccata cttataaaag
      541 ggatattttt taagttagta ttaagattgt gtaatatgat gatatctata ttttatagta
      601 tcagtgctat aaaatcaaaa ataagtcact aattaactac cactccaatt ataagtcttt
      661 ttcccattat tttttacagt tatatggtat gctttttaat ggcttcaaat ataaaagagt
      721 ttaaagcgta acacacttat ggggaagtgg tttttgggga acgctttaaa ctcttcttta
      781 ttattatctc acaatataac ccaaatgtct ttccatttaa aaatcaaagt aaaacttttc
      841 aaatatacag aagtataact atgtgaaaca tcctttcatt aatccataaa aggatacata
      901 aaaaagccac tcatttgagt ggcaatgaag aaaagcttta gcttgtataa tactcttcaa
      961 aaaattctaa cacagaacga ttcaattggc tacattaatg taccctgtag gactcgaacc
     1021 tacgaccgga cggttatgag ccgtctgctc tgaccaactg agctaagggt agtggttgtt
     1081 gccacataaa gccataaaca atcaaccagt agaatgcgtg gcaacaaacc tgttatcgca
     1141 tatcttggag tgtgactatt tatgagtgat agtgaagata tgcgtctcca tatatgtatg
     1201 gttgagacag ataaacatgt atgaaaaacg ttgttaaatc aacgtttttt tattttggtc
     1261 aaggagagaa aagtagagaa atacaaaatt ttttgcattg attttgcatt caaaaaaaca
     1321 ttcaaacatt tagaaatccc caatacgtat tcaggaaaat ctattttaag gtttacaaaa
     1381 agaacttttg ttcgtacact ctttttgagg tgaactttta tgctgatgga aggaaaaaca
     1441 caattatggt ttaagcatgt tccttcaaat aagtttttta attataaact ctagagaaat
     1501 taattcatcc taacataaaa taattgttca ctcaaaagtt tttctagaac aattaaaaca
     1561 gcaggcttca cattcgctat acatttgtaa gaagtaataa ttcctgtact aaaaggcata
     1621 attgctttaa ttattttttg acttctcttc aaacacaaga agtagttgtg taataattgc
     1681 agaaataagg attccaataa tagatataaa atttgacatg gaaacgtcta taacattaaa
     1741 agaataaagt gttgaagaaa gtaaactgat tgaaataacc cctccgtaaa aaatagtctg
     1801 tgaatatacc cacttttttt cagaagacgt acttcgtttg gttctaaaac ctatccctgc
     1861 atttctactc ttatcaaaaa accaaatatt tagaagtaat aatattgcta ttattaagat
     1921 aaaattactg taaaaatcca aaagcta
//
LOCUS       DBBGRF010000137         1933 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000137 DBBGRF010000000
VERSION     DBBGRF010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.145"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..245)
                     /locus_tag="ACIZD4_003002"
     CDS             complement(<1..245)
                     /locus_tag="ACIZD4_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGC5991836.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQ"
     gene            483..1652
                     /locus_tag="ACIZD4_003003"
     CDS             483..1652
                     /locus_tag="ACIZD4_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HGC5991837.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          687 a          323 c          300 g          623 t
ORIGIN      
        1 tcttgccata cctcctgaat ttgaccatca ggagtcgtaa tgaaaatagt atcattttca
       61 tctactaatt ctcttaagtt taaatattgt ttactagatg taaaattcga agctgctaat
      121 gacgagtctt cgcttttact ataaaatcct gttacttgta ttttatgttc ctggaaatac
      181 ttcccgaatg aacaacctac cttgccggct ccaataaaac caacgttcat aattatcacc
      241 tccataaaga agtgagacta caagtcccat tcttacgata tgagcttaaa aataaaaatt
      301 aaatcaaata tacagtatgt ttttttcaaa tatcatccat agttaattta tcataatatc
      361 ccatatttta aaataaaaga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
      421 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      481 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      541 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      601 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      661 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      721 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      781 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      841 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      901 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      961 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
     1021 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
     1081 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
     1141 aagaagtttt attagtagtg acagacggat taagctgtat tgaagaaagt atccatagtg
     1201 tgtatccgaa tgcccaattt caacaatgtt gtgtgcatgt atctagaaat atcgctcata
     1261 aagttcgtgt tcgaggtcga aaagaaattt gtgaggattt caaattggtt taccaagcga
     1321 attcaaaaga agaggcattg gatcacatcg actttatgac taggaaatgg aaaaagcagt
     1381 atccaagagt cgtcaattta ctcttgaatc ctgccctatt aaccttttat aatttccctc
     1441 acgccatcag acgaacaatt tattcgacga acctgattga aggctttaat aagcagctaa
     1501 aacgatatac tcgaagaaaa gaacaattcc ctaatgaaga atctctagag agattcttca
     1561 tttctcaatt taatcaatat aaccaaaaat ttttaggtag aattcacaag ggatttaaag
     1621 aaattcagga tacattagag tcgatgattt aactgtaatt aacagaatgg attttccatt
     1681 tacatataat tcttgacgct accataatct aaataaccat catattcatc tactacttat
     1741 ataattgagt tttattaaac tttttaagtt tctattctat caaatattta aacaatctct
     1801 gcatccgaaa agactacctc gtatagtttt actaacaata tttttattag cgtgttcaaa
     1861 tcctgatttc ttgtatcaat tattttctgt tcactttcaa taagaaaaaa gtctttactt
     1921 ccatggataa taa
//
LOCUS       DBBGRF010000138         1911 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000138 DBBGRF010000000
VERSION     DBBGRF010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.146"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..1582
                     /locus_tag="ACIZD4_003004"
     CDS             <1..1582
                     /locus_tag="ACIZD4_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGC5991838.1"
                     /translation="RIKRLLIMLLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFL
                     KEGLTLNRQARKGFWIIGEERLVRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEM
                     YSATATPIQEVFNQVIIRMRHLLEFENLEKLNYAELLNILIRVTIATVRLRKEATIGR
                     YQLVAEQELDKNDLSYRVMQQVFDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENV
                     IYKVSKAINHSFYQDPQLLTNLYAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAI
                     KQAVRQEISEQNILINDSFVAYIALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQ
                     KINEELNNITIVAFASVLNAQEMIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLK
                     KIQQIIKKILASSNQQERHNLNLRETSINKDTLEDFSKELILKAYTIYERLLVILEAE
                     LIQEYREAFLLHVFLMVHRITFDQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGI
                     NQSEISALFSYIKEGASS"
     gene            1582..>1911
                     /locus_tag="ACIZD4_003005"
     CDS             1582..>1911
                     /locus_tag="ACIZD4_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGC5991839.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          680 a          297 c          366 g          568 t
ORIGIN      
        1 ccgaatcaaa cgtttactaa ttatgctttt agtaacaaaa gaagctatta ctggaatgaa
       61 aatggccaac gcattagatg tcagcaaaga tacgatcatg aatgatttag atgtgctgga
      121 aaataatttt cttaaggaag gattgacctt gaatcgtcag gcgcgaaagg gtttttggat
      181 cataggagaa gaacgtctag ttcgattaac gattgaagag attcttcaaa aagagttcac
      241 ggattatgac atttataaat taatgtcatt gttattgaat ggcggtgaga ctgaatactt
      301 tgaaatgtat tctgctactg ctacacctat ccaagaggta tttaatcaag taatcattcg
      361 aatgcgacac ttactggaat ttgaaaatct agagaaactg aattacgcgg aattactaaa
      421 tattctgatt cgagtgacaa ttgctaccgt tcgcttacgc aaagaggcta cgattggtcg
      481 ttatcaattg gttgctgaac aagaattaga caaaaacgat ctttcttatc gcgtcatgca
      541 gcaggtcttt gattattatc agttgccact gttcgaggat gaatatcatt atatctatag
      601 tgatacattc gacacgattc accagcaaga cgtcatgaaa ctagttgaga atgtgattta
      661 taaagtaagt aaagcaatca accattcttt ttatcaagat ccacaattgt tgacgaatct
      721 gtatgctcat ttatccatgc gattatcgag aaagaaaaaa tttgtcaatg aatataatcc
      781 ttttaaagaa gatatcaagc agaaataccc ggaattattt gatgcgatca agcaagcagt
      841 tcgacaagaa ataagtgaac aaaatattct gatcaatgat tctttcgtgg catatattgc
      901 cttacacttt ttggtttcct acgaaagaga agaagatcta cgaagcgtta gagccgtcta
      961 catttgttca acagggttgg gtgtgactag tctgatcaag caaaagatca atgaagaatt
     1021 aaataatatc actatcgtgg catttgcttc agtattgaat gcgcaagaaa tgattgctac
     1081 caaagatcct gatttggtga ttagtatttt tccaattaat ggcatcgatc gtcctttcat
     1141 caaagtccat ccattaccca ctgaacagga cttgaaaaaa attcaacaaa taataaaaaa
     1201 aatacttgct tcttccaatc agcaggaaag gcataacttg aatcttagag aaacgtccat
     1261 caataaagat actttagaag actttagcaa ggaattgatt ttgaaagctt atacgattta
     1321 tgaacgttta cttgtcattt tggaagcaga attgatccaa gaatatcgag aagctttttt
     1381 gcttcatgta ttcttaatgg ttcatcgtat cacatttgat caacaatata tggcagaagg
     1441 tcgtcaagta gaccagatta ttttagacaa aggaacactg gtaggaaaaa tcgaagcagt
     1501 ttttgcagaa aataatttag gaatcaatca gtcagaaatc agtgcattat tctcatatat
     1561 aaaagaagga gcgtcaagtt agtgaaaatg tcagacgagg ctttaaaaat tatcgaggaa
     1621 agtcaaaatc gggaaaagtt aaaacaagtg attgatctaa ttgaagagcg attagtagaa
     1681 catgctattg taccaaccga gttgcagtgg accattctaa ttaatcactt gaatgagatg
     1741 ctgaaacgtt ctcaaagaaa ggaaacgatt cccgtagtcg atcgggattt gttcaaagaa
     1801 gtatccaaag aagccataac tatttctgat gaaatagtta gaagtatcgg taatttaacc
     1861 gatgatgaaa tatatgtttt gtcgattcat tttgaaacag caaaaaataa t
//
LOCUS       DBBGRF010000139         1758 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000139 DBBGRF010000000
VERSION     DBBGRF010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.148"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..106
                     /locus_tag="ACIZD4_003006"
     CDS             <1..106
                     /locus_tag="ACIZD4_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC5991840.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            523..1122
                     /locus_tag="ACIZD4_003007"
     CDS             523..1122
                     /locus_tag="ACIZD4_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGC5991841.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            1186..>1758
                     /locus_tag="ACIZD4_003008"
     CDS             1186..>1758
                     /locus_tag="ACIZD4_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiH family protein"
                     /protein_id="HGC5991842.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT          627 a          264 c          332 g          535 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt
       61 atttttgagt tacgtaagta ttgatgatct gtctaactta atttgacaat taagattctt
      121 ataaattaga aaagagaaaa taaatattcc atatctactt tattggatcc gtaacatgac
      181 taaattctga atacttttta aagcttatca tttggtaaaa ctgaatataa gttaattata
      241 tagactgaaa attttgaatt ttcagaatag aataacttaa aagtactgac aaaatttttt
      301 aaaggggcaa tattaatgtt ctgagataat caaatcctac cgaaaatatc aaaaatccaa
      361 tgtgacacaa tcagattgtg tctcattcga gggaatcaca caatcccacg tggctctagg
      421 cagaattgaa tttttgcttg gggctttttc cttatattga ttttgaatga gacttattat
      481 atgttataat gcaattaagt atcattggag agggcgaaga aaatgaagac ggtagaacct
      541 attcgagaca aaaaaaagat cgatgcgatg aaggcaatct tggcttcggg aaaatatggc
      601 caacgaaatt tggttctttt ttcgattggg atcaacaccg cctatcgcat ttctgatttg
      661 cgtcaattga agctggccga cgtgctggaa atttcacgcg gtcgcgtggt ggtcaaagat
      721 cgattagcga tgaaggaaca aaaaacagct aaacataatt cggtctatat ttccaacaaa
      781 ttgcgaaaaa cgattttgga gtacgttcaa caggaatttc ctgatcaact ccttcagcaa
      841 gattttgacg gttatttgtt ccctagtcga aaagggacga atgaaccgct caaccgccaa
      901 agtctgtggc gaatcattca tgatgctggc acggcaatcg gattgaaaga cattggccca
      961 cattccatgc gaaaaacgtt cggttacttt ctctataaac aggggaccaa aacagaaatc
     1021 attcagtcct tgttgaacca ttcttctcag cgcgaaacat tgcggtatat tggtattaca
     1081 caagaagaca aagatacagc tgtaaaaagc ttagatttat aatataaaag ttaagtttaa
     1141 acatggatag ttttaaatta gtagattgag tgttgggagg aaagaatgag tacattatat
     1201 attataggaa acggttttga tttaagtcat ggtttaaaaa ctagatacac tgatttttca
     1261 aaatgggttg aaaaaagtca tagtgaaata ttcgataaaa tagacacaat gataaatgaa
     1321 aataatgagg tgagaagtac agctgatgat aagataggtt ggtttaattt tgaaagtagt
     1381 ttgcatgagt taattcaaag tccagtcttt gaagattatg tagaagagtc taaggattat
     1441 ctcataggtt atggacatga agattggtca gattctgccc atcatgattt tcaaaatatg
     1501 gtttatgatt atgttgtttc tctagaagaa ttacaacaac ttttcaagga atggatacgc
     1561 aaagaaatac agccgacaat agaacataaa attccaaaat accaattttc gtccgatgta
     1621 ctattcttta cattcaatta tacagatgtt ttggaaattc tatacaagca accgaaagaa
     1681 aacatatatc atattcatgg cagttatgac gatataataa tcggccactc cgagaatttt
     1741 gacaacttta taggagat
//
LOCUS       DBBGRF010000140         1637 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000140 DBBGRF010000000
VERSION     DBBGRF010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.149"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(183..1502)
                     /locus_tag="ACIZD4_003009"
     CDS             complement(183..1502)
                     /locus_tag="ACIZD4_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HGC5991843.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT          485 a          301 c          325 g          526 t
ORIGIN      
        1 attctttggc acattttatt gaaatatgta tcactaatat ccctatcaac tgattttgac
       61 taaaaagtta cttcaaacat tcactgttca aaaatattga ggaataaatt ttgggtgtaa
      121 ggcattttga gcatacttct ccctggataa cttcccagta aaaaaatcgt tagattgttg
      181 gattagatcc attgactggc tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga
      241 tacacatgat aactagataa tttgagatag actcgtctac ccgtttggac taatttccca
      301 gcaactttca gaaacttcaa tcgaatagaa tgaatggtca ttcccttttg gacttcttca
      361 aagccaatcg ttcttaagaa gttgactaag ttgtaagcta tcaagctgag catcattcgg
      421 acatgattct ccaaaaagcg aggactgtct gttttgtcaa agtaaaagcc agctttcgct
      481 tctttaatga agttctccat tgtgccacgt ttggcataga tagaaaagat ggtatcagga
      541 gaaacatttt ctgatagatt cgtcacgata aattcatgtc gaaagagtag ttcgcccgct
      601 tcacgtgttg agcgtataca cacgcgacga ctttgtgacc aggattgtgc ttgataagtg
      661 gtcgagaagt actgaacttc tcgttcttcc cacttttgat tatcgccata aagtactgat
      721 ttctcagcta tttgacctag tctacgatta ttcttcagtc gaataacata atgactcttt
      781 tttgattcac acgaatcata cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag
      841 atgtcagtgt ttggtagaga gtgattatag tgctctaata aaggtgtgag aaactccttt
      901 acgccttttg atgtatattg atttcctgaa cgtagttcag cttttaagaa gtcaccagtc
      961 aatccgtcaa aagctaccaa tggatggtaa ccataggttt ggtagtgtgt attataattc
     1021 gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc
     1081 gtatcattac ggatgaggcg tgctttatcg ataagttctt ggttcaaagc ttgaagttca
     1141 tggatattct cctcagatag tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt
     1201 tctttcctat ctaaaacagc tttaaacaca ggatcttgtc tcaggagatt agctgcagaa
     1261 tcagctgagt aaccagcaat taattgcata atgaactgct caagtatgga taagttgtca
     1321 tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa
     1381 ccaaagatgt tcatcagctc tttcactagg acgagacccg aatcactcga taattgacca
     1441 cctgtatgag aaatagtgat atttgaattg aattttactt ggtttttgtg taagctagtc
     1501 atgaaaagaa ctcctttctt ttggttggtt tagtcacttt aaccatagca gaaaggggtt
     1561 cttttttcat cacttaacgg gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt
     1621 ttcacatggt tttaatt
//
LOCUS       DBBGRF010000141         1579 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000141 DBBGRF010000000
VERSION     DBBGRF010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.150"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..>1579)
                     /locus_tag="ACIZD4_003010"
     rRNA            complement(<1..>1579)
                     /locus_tag="ACIZD4_003010"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          333 a          486 c          342 g          418 t
ORIGIN      
        1 tctacctgat catctctcag ggatcttact ttcttaaaga aatgggaaat ctcatcttga
       61 ggtgggcttc acacttagat gctttcagcg tttatccctt ccctacatag ctacccagca
      121 atgcccttgg cagaacaact ggtacaccag cggtaagtcc atcccggtcc tctcgtacta
      181 aggacagctc ctctcaaatt tccaacgccc gcgacggata gggaccgaac tgtctcacga
      241 cgttctgaac ccagctcgcg tgccgcttta atgggcgaac agcccaaccc ttgggaccga
      301 ctacagcccc aggatgcgac gagccgacat cgaggtgcca aacctccccg tcgatgtgga
      361 ctcttggggg agataagcct gttatcccca gggtagcttt tatccgttga gcgatggccc
      421 ttccatgcgg aaccaccgga tcactaagcc cgactttcgt ccctgctcga cttgttggtc
      481 tcgcagtcaa gctcccttct gcctttacac tcttcgaatg atttccaacc attctgaggg
      541 aacctttggg cgcctccgtt accttttagg aggcgaccgc cccagtcaaa ctgcccatct
      601 gacactgtct cccaccacga ttagtggtgc gggttagagt ggccataacg caggggtagt
      661 atcccaccag cgcctccatc gaaactagcg ttccgatttc tacggctcct acctatcctg
      721 tacatgcggt acagacactc aatatcaaac tacagtaaag ctccatgggg tctttccgtc
      781 ctgtcgcggg taacctgcat cttcacaggt actaaaattt caccgagtct ctcgttgaga
      841 cagtgcccaa atcgttacgc ctttcgtgcg ggtcggaact tacccgacaa ggaatttcgc
      901 taccttagga ccgttatagt tacggccgcc gtttactggg gcttcaattc gtaccttcgc
      961 ttgcgctaag cactcctctt aaccttccag caccgggcag gcgtcagccc ctatacttca
     1021 tcttacgatt ttgcagagac ctgtgttttt gataaacagt cgcttgggcc tattcactgc
     1081 ggctgatcgt atgatcagca ccccttctcc cgaagttacg gggtcatttt gccgagttcc
     1141 ttaacgagag ttctctcgct caccttagga ttctctcctc gactacctgt gtcggtttgc
     1201 ggtacgggcc gctgttttct cactagaagc ttttctcggc agtgtgacat caggaacttc
     1261 ggtactatta tttccctccc catcacagct tgtccttaag aaaagaagca tttgactcct
     1321 cttcagactt actgcttgga cagacatttc cgatcgtctg cattccttag cctcctgcgt
     1381 ccctccattg ctcaaacaaa aacaacgggt acaggaatat caacctgtta tccatcgcct
     1441 acgcctgtcg gcctcggctt aggtcccgac taaccctggg cggacgagcc ttccccagga
     1501 aaccttagtc attcggtgga caggattctc acctgtcttt cgctactcat accggcattc
     1561 tcacttctaa gcgctccag
//
LOCUS       DBBGRF010000142         1571 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000142 DBBGRF010000000
VERSION     DBBGRF010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.151"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(68..538)
                     /locus_tag="ACIZD4_003011"
     CDS             complement(68..538)
                     /locus_tag="ACIZD4_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991844.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            625..1323
                     /locus_tag="ACIZD4_003012"
     CDS             625..1323
                     /locus_tag="ACIZD4_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HGC5991845.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
BASE COUNT          587 a          223 c          302 g          459 t
ORIGIN      
        1 aaagccaacc gagggggctg actaaaaatg aatagaaaag agaaactaga atgtatatta
       61 ctattactca gtttaattct ttcactaatt tctctattgg gaagtttgta tttttgatat
      121 caacaatttt gtggatttgg gttctattta gagtaaatat catttttgtt tggtgattaa
      181 ggagtttatt aaaattaatt ttccctactt caaatgcaag gtaacaagat atagcacttt
      241 taggaggaat atttagcggt acagcttcag agtatattct attatcatcg actgatcctc
      301 ctttagcaat taatttctta aatggagtag ctgaccatct gcggtttaag ttagcggatg
      361 aaagttctaa attaactaac atagctggtt ctgttgaata gttagaaatg attacttttg
      421 tataaatcat atctgcagcg aagtaagaag cattaagttc aacttctagt tgagggcgca
      481 ttccttttat ttttatccct gttaaaaacg tactcaatat aaaacttatt attgacatcc
      541 attgaaaaat tgttaagtga aaaaaattca aaataaacac caccagtttt taactaaatt
      601 ataccaaaaa ggagagaaga aataatgcaa gaattagtaa ttttgaaaaa taaagaagct
      661 gtgactacga gcttacaagt ggcagaaagc ttcgagaaaa aacatcaaca tgttttaaga
      721 gatattgatg cactaaaaaa agatgtgtcc aattttggac agatgtttgt agaaggtaat
      781 gaaccagatt catatggcag aaatcgacga gttttcttca ttagtagaga tggatttttc
      841 ttgctggcta tggggtttac aggaaagaaa gctatctact tcaaacaaaa atacattgaa
      901 gcattcaacg aaatggaaga tgttattcgc aagaatactg ttcctcaaac aattgaagat
      961 atgatgatct atcaattaga agaaatgaaa gatgttaaaa aagatgtttc catgcttaaa
     1021 gatactatgc gaattagcgg acaacaagag tttgaaatta agcaaaaagg aaatatgaaa
     1081 gttatgggag ttctaggggg aaaagaaagc cgagcttatg aagaaatcag caaaaaagta
     1141 ttctcaaaat tttggtctga atttaaacgt accttttcaa tcccaagata tggcgagtta
     1201 cctcgtaaga gattcgatga tgctgtttca tttattgaaa tgtggttgcc agaaactgcg
     1261 atccgtatgg aaattgatca actgaacaga caacagagac tttttggtga tgacaatgaa
     1321 tagagctgaa gcgctaagaa tagggacggc aattgctaat tgctggtgga aatactataa
     1381 accaatcatc ctaagccaac aacatattga caagcaaaaa gcatggcaac aaataaaaaa
     1441 gtgactccgc cggcaagcaa agagtcacaa agaaaacaca tcataaggag attttagcat
     1501 atggaaaaag aactttccac tctagatcaa tatttgattg atcctgattg gggcaagccg
     1561 aaaattgagg a
//
LOCUS       DBBGRF010000143         1562 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000143 DBBGRF010000000
VERSION     DBBGRF010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1562
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.152"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            132..344
                     /locus_tag="ACIZD4_003013"
     CDS             132..344
                     /locus_tag="ACIZD4_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991846.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAA
                     AVVITAVAKASDSILAWLKFKKEQKK"
     gene            506..1024
                     /locus_tag="ACIZD4_003014"
     CDS             506..1024
                     /locus_tag="ACIZD4_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HGC5991847.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSE
                     IFENISDPLPEEDSRFVLDILNMYRDITFSKNKLKDINSIDNYYIQFKGFDFNSSTEF
                     KLALYAQFFIEKLNRFQEIVEDSDFNTFNSHKPMRGTYIKFLENYNDLKSTNNYQFGN
                     LSYEMISKVLSL"
     gene            1031..1543
                     /locus_tag="ACIZD4_003015"
     CDS             1031..1543
                     /locus_tag="ACIZD4_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991848.1"
                     /translation="MKLNSINDLFAIIGVIANILFSCLNFRFTQKNKKNKLSIEQMKK
                     DIETDLKNDHKERRKIEEYTSLMEKCKATDAIFSFLRKSDEIITRENIDLENEISKLE
                     SIFSDINSLKYLIVEENSDSFLEFEKYLTDLIDNRNNELMRQNIARFLTKLVSEWKSI
                     ISQNMDKLRY"
BASE COUNT          616 a          181 c          242 g          523 t
ORIGIN      
        1 aaaacactat atattccgaa aagtgagtat ctccattcat aaaataatca acatatttaa
       61 aaaatctaat tagctttttt agtcaatcta aagttcttta ttctatgata taatgttact
      121 gtagaaagtt tgtggcggtt tggcaaatcc aattgaagga gcgtggtgcc tatgggctta
      181 ttagcttatc ggacgtactc tgtagaaagg aaatgcctga tttgttctca ttggatcaaa
      241 tcattgctat tatcggagca gcagcagtag ttattactgc cgtagcgaaa gctagcgatt
      301 cgattttagc ttggttaaag ttcaaaaaag aacaaaaaaa atagagccgt ctcaactttt
      361 ggcgaggtag acgagctcta aagctttatt tacatgccat ccgctttgaa cggactacac
      421 tgggcatgtg acagcatgcc ctttcattta tattatatct cattctttta tataatgaaa
      481 gtaaataaat catggaggat aaaatatgga taaatttaat agattaacat taataaatca
      541 gtttgaaatt ttaaaagctt taaatcctaa cgaagaaaaa tactatgctg aaaaaataga
      601 aatactaaca gaaggttacg aatatcacta tagtgaaata tttgaaaata tttctgatcc
      661 attgccagaa gaagattcgc ggtttgttct agacatatta aatatgtata gagatattac
      721 ttttagtaaa aataaattaa aagatataaa ttcaattgat aattattata tacaatttaa
      781 aggttttgac tttaatagct ctaccgaatt taagttagca ctttatgcac aattttttat
      841 tgaaaaatta aataggtttc aagaaatagt tgaagatagt gattttaaca cttttaatag
      901 ccataaaccg atgagaggta cttatataaa atttctcgaa aattataatg atttaaaatc
      961 taccaataat tatcaatttg gaaacttgtc ttatgagatg ataagtaaag ttctaagttt
     1021 gtgatgataa atgaaattaa atagtataaa tgatttattt gctattatag gtgttattgc
     1081 taacatactt ttttcgtgtt tgaattttag atttactcaa aagaacaaaa agaacaaact
     1141 cagtatagaa caaatgaaaa aagacattga aactgattta aaaaatgacc ataaagaaag
     1201 aagaaaaatt gaagaatata cttctttaat ggaaaagtgt aaagcaactg atgcaatttt
     1261 tagcttttta agaaaaagtg atgagataat cacacgtgaa aatatagatt tagaaaatga
     1321 gattagtaaa cttgaatcta tcttttccga tataaattct cttaagtatt taatcgtcga
     1381 agaaaattcg gatagctttt tagaatttga aaaatatcta acagatctta tagataatag
     1441 aaataatgaa ttaatgagac aaaacattgc aagattcctt actaaattag tttctgaatg
     1501 gaaaagtatt atttctcaaa atatggataa attaagatat taaggatgtt agttttaaaa
     1561 ta
//
LOCUS       DBBGRF010000144         1504 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000144 DBBGRF010000000
VERSION     DBBGRF010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.154"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(312..611)
                     /locus_tag="ACIZD4_003016"
     CDS             complement(312..611)
                     /locus_tag="ACIZD4_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC5991849.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(617..847)
                     /locus_tag="ACIZD4_003017"
     CDS             complement(617..847)
                     /locus_tag="ACIZD4_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991850.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1106..1219)
                     /locus_tag="ACIZD4_003018"
                     /pseudo
     CDS             complement(1106..1219)
                     /locus_tag="ACIZD4_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          535 a          243 c          219 g          507 t
ORIGIN      
        1 attgtgagat aataataaag aagagtttaa agcgttcccc aaaaaccact gccccataag
       61 tgtgttacgc tttaaactct tttatatttg aagccattaa aaagcatacc atatttttga
      121 aaaaaagtga gaaaaaaggc ttataattgg agtggtagtt aattagtgac ttatttttga
      181 ttttatagca ctgatactat aaaatataga tatcatcata ttacacaatc ttaatactaa
      241 cttaaaaaat atctcctttc ataagtatgg tgataaaatc cgttccgggc taccttttta
      301 ggtagcctac tttaatcttt gtatctttct ggatcaacga aagtatactt tatatagtca
      361 taacgccgat gatcgcttcg agcgtctagc acatcagtca cgatatcaaa caaaaaatat
      421 acgtctttct tcattctagt tttcgcagca gggattttaa agtagttctt attagaatag
      481 tagagattaa ttaataagct atcttcgatt gctaaaaaga aaacttctga atcccacacc
      541 ttataaaaat ctttgacaaa tctattcgaa ggatcaaatt taaaccataa ttgcgtctca
      601 ttaaaaagca taaccattac tccgatctat ttttaaactt agtctctacc tctaatatat
      661 atcgagtttt tattttgcct tcagagaata ctgtttcttt ttttgcagtt acaggttgtt
      721 tattttcgga aaaagctaat atagctaaaa ttgaaacatc catctggaat ttgtcttttt
      781 cgttgctttg ctcataaaaa tctgcatatt catcactaat attttttcta ataaattctt
      841 ccatcataaa gatcacctcg aaaagagtat acgaacaaac gttctttttg taaaggtgga
      901 atttattata ctaaataaat aggtgaacaa gtacttgtgc caaattatgt gccaaaaaaa
      961 atcgaattta ataaaacaca aacaaaaaga aatcctatta tgataacatt tcttataata
     1021 acaaacacaa cagaagacgt gtaatagtta gtcaggaacg tacaaataac ccctgtatcc
     1081 tttgcggtac agggggttat tttgtataag tagacattgt agtttctaaa ctgctatgtc
     1141 ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata gatgcatgcg
     1201 tatgtcttag tccatcaata aacagtcgaa gagaaaatag ggaaaaattg attactaaag
     1261 aaaaacttac taggtcgacg gtgtagttga ttttcatact tcaatagatt cgaattaaac
     1321 gatttcgatt ggcttatacc agtcctatcc aacgaaagat atatcgttct taactctagc
     1381 ggtataactt gaagctttac gtaaagccaa tgggaatgaa ctggagatga ctttttatta
     1441 tttttagtaa tagctgatgg gttaatactt acaactttcc ttttcaaagt accatataaa
     1501 aaaa
//
LOCUS       DBBGRF010000145         1435 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000145 DBBGRF010000000
VERSION     DBBGRF010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.155"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(77..397)
                     /locus_tag="ACIZD4_003019"
     CDS             complement(77..397)
                     /locus_tag="ACIZD4_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5991851.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            696..>1435
                     /locus_tag="ACIZD4_003020"
     CDS             696..>1435
                     /locus_tag="ACIZD4_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HGC5991852.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEG"
BASE COUNT          537 a          247 c          222 g          429 t
ORIGIN      
        1 tccatataaa ctactttcaa attgtattcg ctcaacattt ctttcaattt caaatacata
       61 caaaccatca ctccaactat tcattttcct ctaaagcttt agcaattgca atcgctttac
      121 gcattgtctc cttagatatt tcttttccat caaaagaaaa aacagtatcg tcttctgata
      181 aatccacatg tttaggggtt tctctttctt ctctacctag aaggtagtct acagagacat
      241 cgaaatagtc agcaatccga cttaattcat ctgaattagg agtattattt ttccactttg
      301 ctagataacc gttagaatat ccaaaattaa tttctaactg ccgtatagat atctttttcc
      361 tcttcgccaa gtcttttatt atttcatagg tattcatcga taaaacaacc tttctaaatg
      421 tttacaaaaa aagtttagaa aaatacgcag aaataatttg actaattctg agtaatgagc
      481 tatactatat cttgtaaaca gatttaacaa ctaaaaagac aacaaaaaac actattgata
      541 tgtaaatgca gaccgccaag aaagctttaa aatcaatgtt tttatgtctt atttaattat
      601 gctcttagta tagagtatta ctcagatact gtcaattgaa tttagaaaaa agttgttaaa
      661 tttgtttacg aatataaaag aaaggaatga gaaatatgaa cacaccgcaa atttttaatt
      721 tcgaacaaaa cgaagttcgg acaattttag taaatgatga accatatttt gtaggcaaag
      781 acgttgcgag tgttttgggt tattcaaaca ctaaagatgc tttgtcgcgg catgtagatt
      841 tggaagataa gatggggtcg cgaatcacga cctcaggtca atcaagagag atgacaatca
      901 tcaacgaatc tggtttgtac agtttaatct taaaatcaaa acttccctct gccaaaaaat
      961 ttaaacgttg ggtaacaagt gaagtgttgc cagcaattag aaaacatgga ggttatctaa
     1021 ctccagaaaa agtagaagaa gctttgctta atccagatac aatcattcaa ttagcaactc
     1081 aactaaaaga agaaagaact ggaagattaa tcgcagaaca aaagattgca gagtacgaac
     1141 ctaaaatctc ctatttagat agcatattat cttctacaga ttcagtaaca attagtcaga
     1201 ttgcagcaga ttatgggatg tctccacaac agatgaataa attacttcat aaactaggta
     1261 ttcagaaaaa agtcggtaac caatggttat tgtgcaaaaa acacatgaac caaggataca
     1321 caaaatctca tacaactgag atcccgaaag ccgatggtgg cactaaaatt gtaatgaata
     1381 ccaaatggac acagaaaggg cgtctattta tctacgaatt actaaaaaaa gaagg
//
LOCUS       DBBGRF010000146         1417 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000146 DBBGRF010000000
VERSION     DBBGRF010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.156"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(150..1337)
                     /locus_tag="ACIZD4_003021"
     CDS             complement(150..1337)
                     /locus_tag="ACIZD4_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HGC5991853.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          412 a          308 c          249 g          448 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttc
//
LOCUS       DBBGRF010000147         1374 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000147 DBBGRF010000000
VERSION     DBBGRF010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.157"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            33..1372
                     /locus_tag="ACIZD4_003022"
     CDS             join(33..474,474..1372)
                     /locus_tag="ACIZD4_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HGC5991854.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          576 a          177 c          239 g          382 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggactatctc cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DBBGRF010000148         1372 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000148 DBBGRF010000000
VERSION     DBBGRF010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.158"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            37..1338
                     /locus_tag="ACIZD4_003023"
     CDS             37..1338
                     /locus_tag="ACIZD4_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC5991855.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          446 a          275 c          253 g          398 t
ORIGIN      
        1 ttgaatcacc acaacacaat caaaggagcg ttctgtatgc ctgatcttca tcatatcaaa
       61 ctactacttg gaatcaaaga taaaaacatt ttcatcacaa atgtggaatc gaagagcatt
      121 aagaatatca agagtcttgt tgtttctgcg acgttaagta aagaaattcg tcgctgtcct
      181 ttgtgtaaac agatgaatca tgaaggcatg atcgttaaga acggaaagaa aaaatcgctc
      241 attcaactta ataaatgtgc gaaccaactg acttatcttg ctttagcgaa acaacgctac
      301 cactgtcgtg gctgccacac ctattttacg gcgaatacct acattgtcga tagaaactgc
      361 tttatcgcta aacaagtgcg ctataaaatt ttagaagagc taactgaaaa acaagcaatg
      421 acgacaattg ctaagcattg cggcgtttct tggtcgaccg tttctcggac actcgcttct
      481 ctgatcccca tgacaaaagt aaaaagaaat tggttaccgc gttgtttatt aatggatgaa
      541 tttcgttcac tgaaaaatca agtcggtccc tactcctttt cttgtatgga tggcgatact
      601 ggaaaattac tggatattct tccttcacgg aagaaaaagg ctctcgtttc ttattttatg
      661 caatttgaac gacgcgcacg attgaaggta aaggtcatcg tgacggacat gaatgtttct
      721 tatgcctctc tgataaagga atgttttcca aaggcaaaac tcgttgtgga tcgttttcac
      781 attgtcaaac atctcattcg taaatttgag gatattcgcg tacgaatcat gaaaagcttt
      841 gatcgaaacg atccaacaca agccaaatat tatcgacaat taaaggcgtt gtctcggctt
      901 ctgatcaaac gacaggacaa gcttgtttat gacaaatgga ccaaatggcg caattttggt
      961 tgggcgtatc tcaccgaaag tgaagtggtg gatcgtctgc tttcgatctc tgacgaatta
     1021 cgaatcgcct atttttacta tcaagaaatt cttcaagcgt ttcacgacaa agaggcggac
     1081 actttcttta aacttgtaag aacgatgccc aattccgttc caaaagaact gcattctata
     1141 aaaaaagctt ttataaacta tgaatccggc attcgtttag ccctcgaatt gccttattca
     1201 aatgccaaaa tagaaaatct gcatacccac atcaaagcat tgaaacgagt cgcttatggc
     1261 tttcgaagct ttcggaaaat gaagaccaga attttcttac taaataatct gattacctat
     1321 gaatcaaaaa acatctaaag tagaaaagga attctacctt agatgttctt at
//
LOCUS       DBBGRF010000149         1362 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000149 DBBGRF010000000
VERSION     DBBGRF010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.159"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            82..>1362
                     /locus_tag="ACIZD4_003024"
     CDS             82..>1362
                     /locus_tag="ACIZD4_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HGC5991856.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          464 a          262 c          257 g          379 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat ta
//
LOCUS       DBBGRF010000150         1359 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000150 DBBGRF010000000
VERSION     DBBGRF010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.160"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..208)
                     /locus_tag="ACIZD4_003025"
     CDS             complement(<1..208)
                     /locus_tag="ACIZD4_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991857.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIG"
     gene            complement(305..757)
                     /locus_tag="ACIZD4_003026"
     CDS             complement(305..757)
                     /locus_tag="ACIZD4_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991858.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(764..1312)
                     /locus_tag="ACIZD4_003027"
     CDS             complement(764..1312)
                     /locus_tag="ACIZD4_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HGC5991859.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
BASE COUNT          487 a          264 c          132 g          476 t
ORIGIN      
        1 tgcctatctt ttttacaaat atttcatttg gtgtacagac taataaaaca atatttgtaa
       61 tcaatccttg cactaaagaa ttaaaaggaa gactatttaa aacagggtgt gcataactat
      121 aacatgtgaa gtagttattt tgaactttaa cttttaaaaa ctttaaaaat aatcttattt
      181 gttcttctaa acaatcatct atactcatat aatcactcca ctaattaatc tccccaaaaa
      241 gacacagcat taagagatat accaacacaa cagtgcaaat aactctacat cttccttcgc
      301 aaccttattt caataaacca taaaaattat tttttaatag aaactgaaaa ttaaaactag
      361 aaaaagtagt tttaccgaat gtaagagcat catcaccatc aatatagaaa tacattcttt
      421 tccagttaca tttaattttt aaacaaaatt ctccccaaaa aggaactttt tctagtgaaa
      481 acttggtaat ctctttgtaa ttaattcttg ttaaagaata attaaacact tcatttttac
      541 ttgttatttt ttcattgact ataactagtt catctggtaa aaaaattaac caacaaacat
      601 cgacaaacag taaatgatat aatccatttc cacctccaag catattcaat actggtgaac
      661 atgccttaga aacacgaata tagttatggt ttaaatagat attttcttta aacattgctt
      721 gtttaaaagc catatgctct tgttctaaac ttttcataaa cttttactct aatgcacagc
      781 tagcagcagc tgctgcaatt cctgctacaa tatttacctt agctaactct ttagctgcag
      841 cttttcctaa ttgtttttct gcaattttta ataataaatc cgcagctttt tcaaaattaa
      901 aagcttttaa tgcttcaata aaatctccct gcgtacctat agcccaagcc actcctcctc
      961 caggaagaga attaatggct acacatccag catatcgttt ccaatcaact ttctccattc
     1021 taggaacaat aatatgttca taaaagactc ttgctgctct tccttgttcg ttatcttgac
     1081 tgattcgttc acgaatagca ccaaaatcct ttatatggta tacaccatgt tcgtctaaaa
     1141 aaccaactgt atcaaaataa aaagttaatt catctactaa tttattcttt atttctaaat
     1201 caactgtatt cactttttct gtggcataca cacttgttcc agtactaaca aaagtactta
     1261 aacctaataa gaaaacacct aaaacaccaa atattttaat tattcttttc ataatttctc
     1321 ctccataaaa aataagttac tttttaaata tcttgttta
//
LOCUS       DBBGRF010000151         1338 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000151 DBBGRF010000000
VERSION     DBBGRF010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.161"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            82..>1338
                     /locus_tag="ACIZD4_003028"
     CDS             82..>1338
                     /locus_tag="ACIZD4_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HGC5991860.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRI"
BASE COUNT          453 a          252 c          257 g          376 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa gctccaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcgatgatct atccttacac caatggaaaa
     1261 atagaagcga agaataccca tataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaatt
//
LOCUS       DBBGRF010000152         1336 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000152 DBBGRF010000000
VERSION     DBBGRF010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.162"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            90..1169
                     /locus_tag="ACIZD4_003029"
     CDS             90..1169
                     /locus_tag="ACIZD4_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC5991861.1"
                     /translation="MTHSNDNTLRRKGKHLSYSERAQIAILKKENYSNRQIAKVIGCV
                     PQTINNEIHRGTITQLKRQKQKGKTYDYYIERYDADAGQAAYDRHRLNSGRRPKWADT
                     SAFIDWADEKMLNDKWSPDVVVGFARKHDLFDPSIIPCTTTLYGWIDKGIMRTKNMDL
                     LEKLSRKSKVSTQVKRSHKRVLGQSIDKRPAEVDSRQTFGHWEIDTVVGNKEKSDAVL
                     LTLVERQTRFEIILKVNGKDQASVNQAIQSLQTRSGDAFSTLFKTITSDNGSEFAGLH
                     DALKDSLDVYFSHPYASFERGTSENQHKFIRRFIPKGKPISQIADVQCLRIQQWMNDY
                     PRKILGYRTPHDCFVHALRSERQAA"
BASE COUNT          435 a          290 c          282 g          329 t
ORIGIN      
        1 agccacttaa gctaacataa aaaaacgcca tgtgaatttc atgttatatt gaagttacca
       61 ctaactctca atagacagga tgaattcaca tgacgcactc taacgataac acattaagac
      121 gcaaaggaaa acacttatct tattcagaac gggctcaaat tgctattttg aagaaagaaa
      181 actactccaa tagacaaatt gccaaagtga ttggttgcgt tcctcaaaca atcaataatg
      241 aaatacatcg cggaaccatc actcaactta agcgtcaaaa acaaaaggga aagacgtacg
      301 attactatat cgaacgatat gatgccgatg ccggacaagc agcgtatgat agacaccgat
      361 tgaactctgg ccgtcggcca aaatgggcgg atacgagtgc atttatcgac tgggctgatg
      421 agaaaatgct aaacgataaa tggtcaccgg atgtggttgt cggatttgct agaaaacatg
      481 acttgttcga tccctctatt attccttgta caaccaccct ttatggttgg atagacaaag
      541 gaatcatgcg tacaaagaat atggacttgt tagaaaaact gtctcgcaaa tcgaaggttt
      601 ccacacaagt taaacgatca cataaacgcg ttcttggcca gtcgattgat aagcgtccag
      661 ctgaggtcga cagccgccaa accttcgggc attgggaaat cgatactgtc gtaggaaata
      721 aagaaaaatc ggatgccgtg ttgcttacat tggttgaacg acagacacgt tttgaaatca
      781 ttttgaaggt gaacggtaaa gatcaagcgt ctgttaatca ggcgatacag tctcttcaaa
      841 cacgctcagg tgatgccttt tctactttat ttaagacgat aacgtctgac aatggttcag
      901 agtttgcggg ccttcatgac gctctgaagg actcgctgga tgtctatttc agtcacccct
      961 atgcctcatt tgaacgaggc acgagtgaga atcaacacaa atttattcga cggttcatcc
     1021 ctaaagggaa gcccatcagc caaatcgcgg acgttcagtg cttacgtata caacaatgga
     1081 tgaacgatta tccaagaaaa atactaggct acagaacacc acatgactgt ttcgttcatg
     1141 cgctaaggtc agaacggcaa gcggcttaac ccgtgagggc ttgacaacga gcctccttcg
     1201 acatgacttg aatgctggaa agctggccta ggccagcttg tcaaaagact atcatgtctc
     1261 agctcattat caagccctca ctatataggc gaaacgacta acaatttcac aaggaattaa
     1321 ataatatcaa gtggct
//
LOCUS       DBBGRF010000153         1311 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000153 DBBGRF010000000
VERSION     DBBGRF010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.163"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            102..>1311
                     /locus_tag="ACIZD4_003030"
     CDS             102..>1311
                     /locus_tag="ACIZD4_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC5991862.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVL"
BASE COUNT          412 a          258 c          252 g          389 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      661 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      721 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      781 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      841 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      901 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      961 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
     1021 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1081 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1141 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1201 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
     1261 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta a
//
LOCUS       DBBGRF010000154         1297 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000154 DBBGRF010000000
VERSION     DBBGRF010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.164"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            141..398
                     /locus_tag="ACIZD4_003031"
     CDS             141..398
                     /locus_tag="ACIZD4_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991863.1"
                     /translation="MSKLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="ACIZD4_003032"
     CDS             complement(630..1061)
                     /locus_tag="ACIZD4_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGC5991864.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          492 a          169 c          161 g          475 t
ORIGIN      
        1 ttctgtccac gttcatatta ctccaaagtt ttcctcattc caaaagaaaa gcacagaata
       61 cacaaagaag cgtttttatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaaat tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 acaaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatccc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca cacataaaaa taaaaaacat
     1141 ttgtatttta tcaaagtttt attatacttg tcaatttgtg tacatcctaa aatataagct
     1201 atttgtttac ttctgtagaa tatatacttt gttgttagat aagttgcaca tgtttataga
     1261 atctaaataa taaattttta tgtaccgccc ctccaaa
//
LOCUS       DBBGRF010000155         1275 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000155 DBBGRF010000000
VERSION     DBBGRF010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.165"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(31..1203)
                     /locus_tag="ACIZD4_003033"
     CDS             complement(31..1203)
                     /locus_tag="ACIZD4_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HGC5991865.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIGNSHNRL
                     KSTNLLERLNQEVRRREKIIRIFPNRTSANRLIGAVLMDLHDEWLSSTRKYIKFDQ"
BASE COUNT          345 a          265 c          245 g          420 t
ORIGIN      
        1 taaaatacta tacaatgttt taccggtctc tcattgatca aacttaatat attttcttgt
       61 agaactgagc cattcgtcat gaaggtccat aaggacagct ccaattaatc gattggcaga
      121 cgttcggttg ggaaaaatcc gaataatctt ttctcttctg cggacttcct ggttcagtcg
      181 ttcaagaagg ttggtgcttt ttagccgatt atgactattt ccgataaccg tgtattgaaa
      241 ggcatcttcg aagccattat ccaatatttc gcaggctttt gtatatttag gctggtcgat
      301 atattcaccg actaaggcat tcttagctgt tcgagcgagt tcaatatccg taaacttaaa
      361 gatcgctttt actgcttctc taaacggttt tgaattcttt tttggaatgg aactgaagat
      421 gtttcttaaa aaatggacct ggcatctctg ccaacttgcg ttggtaaatg acttacgaat
      481 cgcagacact aggcctttat gggcatcaga aatgatgagt tctgtcccct ttaggccgcg
      541 ttcttttaag tattcaaaga agatggacca tgtgtcatca ctttcttcat tttgaatcat
      601 gaagccaatg atttcacggt cgccaccttc tgttatcccg atcgcaatat ggcagctttt
      661 agaaagcact cgatggtcct cacggacttt tatgtagaga acatcagtca tcagataagg
      721 ataattcgta cctgagagtg aacggttctg ccattcgttg accatcgggt ctaactgctc
      781 agtcaggcta gaaacaaaag atttcgatac agattttcca catagctctt caacaatctt
      841 tgaaacttta cgtgtcgaaa cgcccgaaac atacatctca agcattgaag cgagcagtgc
      901 cttttcattt cgctgataac gctcaaacac cgtcggtgaa aattcaccat cacgtgttct
      961 aggcactttt aattcgagtg tacccacacg agtcgtaaag tctcgctcat aatagccatt
     1021 tctttgactc tgacgacttt ctgaacgttc atagtcatcg gcttgaatat attctgttcg
     1081 ttgattttcc atcaattggt tgaaaacagt ggttaaaata tttttagaaa catcatcttt
     1141 taccgaatgt tcaataatac tttgaacctc ttcgttgttc agtgtaaaat gtacttgggt
     1201 catgtaacgt cctcctgggt atgtttttgt ggttaaaaac attgtaccgt aaaagggctg
     1261 ttacatggcc tttta
//
LOCUS       DBBGRF010000156         1215 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000156 DBBGRF010000000
VERSION     DBBGRF010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.166"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            414..947
                     /locus_tag="ACIZD4_003034"
     CDS             414..947
                     /locus_tag="ACIZD4_003034"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGC5991866.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          389 a          226 c          225 g          375 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttattg agaagttgtg aaatcagcgt
       61 cctgacctga gtattagaga aacaaatggc aaaatagttc ctcatatttt gctatttttt
      121 gagctaatac cgagggtcag ctgattgaac accgtttagt ggagaagttg tgaaaaagtc
      181 gcctactttc gagtcgtaag aaattttttt gaaaatggtt cctcacaact ttgcataaat
      241 ttgacttaat accgagaagt catgatcccc atctaactcc aaatcacaag gaatgagttc
      301 aaaaactagc ttttctcaac aaatattaca taaaaaattc tatgtttttt gttaaattta
      361 tttgcttttt tcaaaagtat gttacagtaa tttcccaagg aggttttaca gaaatgaatt
      421 ttgttgccat ggattttgaa actgccaatc atcagcctta tagtgcttgt tctcttgcgc
      481 tagtcatggt aaaaaatagc cagatcgttg atgaattcta tacattgata cagcctgaga
      541 ctcctttttt ctggcgaaat gtccaaattc acggaatcca tcaagaagac gtacgcaatg
      601 cgccgaaatt cccagaagtc tggcaaacta tccaaccata ttttcaaaaa aatcgtttag
      661 tcgttgcaca taatgctgct tttgatacaa aggtcttagc gggatgctta gattattatc
      721 atcttgaaca gcctaattat ctttctttat gtacagtgaa aagtagccgt cgcctgtttc
      781 ctgaatttcc aaatcatcga ttgaacactg tgtgcgaaaa tttgaacatc caattagatc
      841 atcaccatga tgcattggaa gatagtcgtg catgtgcgga aatcctgctt tatcaagaaa
      901 aaaaattcgg gacagatcca ttgaaaaaac ttgtgactat aaagtaaaag aatacttatg
      961 aaacacacaa agaggtcgtg agcctgccgt ttcactccga gtcacaagga gcaatttcaa
     1021 aaaatagctt ctcatgttta ttaaatattg tgactggtga ccgaggagct ggcaggagaa
     1081 caccgtttat tggagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
     1141 acaaaaatag cttctcatat ttttcatttg gttggactta ttaccgcaga tgcaagcttt
     1201 tggacaccgt ttacc
//
LOCUS       DBBGRF010000157         1193 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000157 DBBGRF010000000
VERSION     DBBGRF010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.167"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..1076
                     /locus_tag="ACIZD4_003035"
     CDS             <1..1076
                     /locus_tag="ACIZD4_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGC5991867.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DBBGRF010000158         1111 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000158 DBBGRF010000000
VERSION     DBBGRF010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.169"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            85..624
                     /locus_tag="ACIZD4_003036"
     CDS             85..624
                     /locus_tag="ACIZD4_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991868.1"
                     /translation="MWSLVGIVLIIFTVTAATEANYSHKIQSYKGRLVMTKKDVTRYT
                     SSRTGGLYDYAPLDALKYKDHLKKHEVKVGDRWENASHKAYNSKIVYTVEDADEQNIT
                     LPVFNYWGTVVKVNGKKSTIENDNGLVSIKGTGKRTIVEVSSTYPTTMILSLLISSIT
                     FIFLFTRYLIRCCGEMKID"
BASE COUNT          397 a          150 c          186 g          378 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagagc aaatataaaa tttaatgaaa atatagaact aaataggaaa
      781 acgtagacgt aattttctac gttttccttt tcatatatat taaatattac ggaaaattat
      841 ataaactaat ttagtgtttt gtttgtaatt cctaattttg ctccactttt agataatttt
      901 taggtctatt taactcatca gacattctat gctcattttt ctccaaattt gtttcaactc
      961 tttcgtactt aattttgcgt atttgaaaat tcttctttta gagtactttt attacgatac
     1021 tagtatgata tatatctata gcaaacaggt gaactactca ccacttagct aaacctgacg
     1081 gttcttaacg cttgaagtgg gagcttcttg g
//
LOCUS       DBBGRF010000159         1067 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000159 DBBGRF010000000
VERSION     DBBGRF010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.170"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(170..907)
                     /gene="erm(B)"
                     /locus_tag="ACIZD4_003037"
     CDS             complement(170..907)
                     /gene="erm(B)"
                     /locus_tag="ACIZD4_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HGC5991869.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
BASE COUNT          311 a          171 c          187 g          398 t
ORIGIN      
        1 gggtcccgag cgcttagtgg gaatttgtac cccttatcga tacaaattcc ccgtaggcgc
       61 tagggacctc tttagcttct tggaagctgt cagtagtata tctaataatt tatctccatt
      121 ccctttagta acgtgtaact ttccaaattt aaaaaagcga ctcatagaat tatttcctcc
      181 cgttaaataa tagataacta ttaaaaatag acaatacttg ctcataagta atggtactta
      241 aattgtttac tttggcgtgt ttcattgctt gatgaaactg atttttagta aacagttgac
      301 gatattctcg attgacccat tttgaaacaa agtacgtata tagcttccaa tatttatctg
      361 gaacatctgt ggtatggcgg gtaagtttta ttaagacact gtttactttt ggtttaggat
      421 gaaagcattc cgctggcagc ttaagcaatt gctgaatcga gacttgagtg tgcaagagca
      481 accctagtgt tcggtgaata tccaaggtac gcttgtagaa tccttcttca acaatcagat
      541 agatgtcaga cgcacggctt tcaaaaacca cttttttaat aatttgtgtg cttaaatggt
      601 aaggaatatt cccaacaatt ttatacctct gtttgttagg gaattgaaac tgtagaatat
      661 cttggtgaat taaagtgaca cgagtattca gttttaattt ttctgacgat aagttgaata
      721 gatgactgtc taattcaata gacgttacct gtttacttat tttagccagt ttcgtcgtta
      781 aatgcccttt acctgttcca atttcgtaaa cggtatcggt ttcttttaaa ttcaattgtt
      841 ttattatttg gttgagtact ttttcactcg ttaaaaagtt ttgagaatat tttatatttt
      901 tgttcatgta atctctcctg aagtgattac atctataaac aaatacagaa gttaaacgat
      961 ttgtttgtaa ttttagttat ctgtttaaaa agtcataaga ttagtcactg gtaggaatta
     1021 atctaacgta tttatttatc tgcgtaatca ctgtttttag tctgttt
//
LOCUS       DBBGRF010000160         1062 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000160 DBBGRF010000000
VERSION     DBBGRF010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.171"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(36..>1062)
                     /locus_tag="ACIZD4_003038"
     CDS             complement(36..>1062)
                     /locus_tag="ACIZD4_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HGC5991870.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          178 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca ac
//
LOCUS       DBBGRF010000161         1001 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000161 DBBGRF010000000
VERSION     DBBGRF010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.172"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            369..1001
                     /locus_tag="ACIZD4_003039"
                     /pseudo
     CDS             369..1001
                     /locus_tag="ACIZD4_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac c
//
LOCUS       DBBGRF010000162          991 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000162 DBBGRF010000000
VERSION     DBBGRF010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.173"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            52..>991
                     /locus_tag="ACIZD4_003040"
     CDS             52..>991
                     /locus_tag="ACIZD4_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC5991871.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKD"
BASE COUNT          355 a          180 c          190 g          266 t
ORIGIN      
        1 gtgctacact caaaatagtt ccgacgaaag aattataagg agtgagtaca aatgacctat
       61 aaccatctta caccaactga actcgtaatg atagaagctt atttcaatca atcacaacct
      121 gtttcaaaag tagccaatct gttacaacgt tctcgacaaa ctatttataa ggtctatcgt
      181 tttcttaaat ctggtggaag cgcaatgagc tactataaac aatataagaa aaacaaacgt
      241 aactgcggaa gacatccgat tgttttacct gatgagcaac aggaatacat tcaaaaaaag
      301 gttgttcaag ggtgggctcc tgatgtcctt attggtcgag cagagtttcc tattgcttgt
      361 tcggtacgca cactgtatcg aatgtttaaa gataaaacct ttgacactca cgatttacca
      421 atgaagggaa aaagaaaacc aaacggtcat aaagaaaaaa gaggaaaaca agggtttcgc
      481 cggtcaatcc gagacagaaa gacagactat acccagtttg atcatgaatt tggtcacctg
      541 gaaggtgaca ctatcgtggg tggaaaacat aaaagcgcgg tcatcacatt agttgaacgg
      601 ctatctaaag tcatcattac cttgaaaccc gaaggcagac aggctaaaga cattgaaaat
      661 aggctgaatc aatggtttcg ttgtgtccca aaaaacttat ttaaatccat cacatttgat
      721 tgtggaaaag aattctcaaa ttggaaaaag attagtaata ccaacgatat ttcaatttat
      781 tttgcggatc caggaacacc ttctcaacga ggattgaatg aacattcaaa tggcttatta
      841 cgtaaagatg gtttgtataa agctatggat tttaatggtg tatctgaaac ctttatccaa
      901 tcggtggcat cgaaacgaaa tcatattcct agaaaatcat tacactatcg gacaccaatg
      961 gaagtatttt tgagttacgt cacaaaagat g
//
LOCUS       DBBGRF010000163          978 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000163 DBBGRF010000000
VERSION     DBBGRF010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.174"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..>978)
                     /gene="aph(2'')-I"
                     /locus_tag="ACIZD4_003041"
     CDS             complement(<1..>978)
                     /gene="aph(2'')-I"
                     /locus_tag="ACIZD4_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HGC5991872.1"
                     /translation="FLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHE
                     GKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYI
                     FKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFL
                     TPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSG
                     IIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYY"
BASE COUNT          322 a          166 c           76 g          414 t
ORIGIN      
        1 ataatattct tcaactatat cttgatattc ttttgctttc tcaatatcta tatttccata
       61 cattcttaat atatcttctc caaaatttgt tcctatttct tcttcactat cttcaagtaa
      121 gtatataaaa tcacaatatt catctataat tccagaatct ccaaaatcaa ttattccagt
      181 taatctatta ttgccatcta acaatagatg attacaacta aaatcattat ggcataaaca
      241 ctttttaccc tcaaaaactg ttgttgcatt tagtctttcc ataaaacttt ctatataatc
      301 tttttctata tcagttaaat cattataaat agtttcacgc aacaatatat actcttctaa
      361 tacattttgt ttattatcaa tagtacattc actaatatct gtataatcta aaccgtgcat
      421 ttgtcttaaa aaactggcaa tatctcgttt taacaaattt tgttcttctt ctgacatagt
      481 agaataaatt tctggtgtta aaaaagttcc tttaatttct ttataaccta gtatagataa
      541 ttcatcacta atatacgaat attcaatatt aggaattttt acattagttt ctaaatttgt
      601 atttaaaaaa ttatatattg ctttttcttt tgcataacct tttttcttat tagtactaaa
      661 ttttgtttta aaaatgtatt cattattaac taaatatgcc acactatcat aaccactacc
      721 gattatttca atactatcta ctttgaaatt atcaaagtaa tgctcaatta aatatttcat
      781 tgccttaaca tttgtggcat tatcatcata tctatattcc attaaataac aatcttcttt
      841 tttgccctcg tgtaattcat gttctggcaa atcttcaata attctaaaac cagatttttg
      901 gtatgccctt attgctcttg gattattttt atgagggtct aaaataactg cattagcatt
      961 tctttctttt ttcaaaaa
//
LOCUS       DBBGRF010000164          973 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000164 DBBGRF010000000
VERSION     DBBGRF010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.175"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..>973
                     /locus_tag="ACIZD4_003042"
     rRNA            <1..>973
                     /locus_tag="ACIZD4_003042"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          303 a          193 c          280 g          197 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaa
//
LOCUS       DBBGRF010000165          907 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000165 DBBGRF010000000
VERSION     DBBGRF010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.176"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..878
                     /locus_tag="ACIZD4_003043"
     CDS             <1..878
                     /locus_tag="ACIZD4_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGC5991873.1"
                     /translation="SLNQPLPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENR
                     QLNPLRDYFLRYPRKVREQVRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRA
                     FTNHRIQVMKTFKKRDRRSKHLKKYWRLLQKNAWELKGQHRYWRPSFRDHLTEAEIVD
                     RLLSYDDSLKRGYEVYQDFLSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRT
                     EIKRALRVPYSNGPIECLNNHIKVLKRIAYGFRNFQNYQERIFLYRGKYFKKTKNTTQ
                     LTKARTTTRLDKIAV"
BASE COUNT          290 a          202 c          184 g          231 t
ORIGIN      
        1 tttctttgaa ccagccgtta ccagaagtgg tgtgtttcga tgaattcaaa tcggtgaaaa
       61 acgtctcggg agccatgagc tttgtcatga tggacggcaa gacccatcaa ctgattgata
      121 ttgtggaaaa tcggcaacta aatcctttac gcgactattt cttgcgctac cctagaaaag
      181 tccgtgaaca agtacgtcta gtggtttcag atttctatac accctatcgc acattggtga
      241 aagagtgctt tccgaatgcc cgaatcgtcg ccgatcgctt tcatattagc caacacatcg
      301 gtcgggcctt taccaaccac cgaattcaag taatgaagac ctttaaaaaa agggatcgtc
      361 ggtcgaagca cttaaagaaa tactggagac tacttcaaaa gaatgcgtgg gaattgaaag
      421 gtcagcatcg ctactggcgt ccgtcatttc gagatcatct gacagaagca gagatagtcg
      481 atcggctatt atcttatgat gactccttaa agcgaggcta cgaagtctac caggattttc
      541 tttccgctat cagaagacaa gatgttcctg aattcgtcgc gctcctaaaa gaagactaca
      601 aggagttgcc agagcactac caaccagtgt tcacgacctt caagaaatat cgaacagaaa
      661 tcaaacgagc gttgcgagtt ccctattcca acggccctat agaatgtttg aacaaccata
      721 tcaaagtact aaaacgaatt gcctatggct ttagaaactt tcaaaactac caagaacgaa
      781 tctttttata tcgaggaaaa tattttaaga aaactaagaa cactacccaa ctgactaaag
      841 ctagaacaac aacacggcta gacaagatag ctgtctagcc gtgtgagtat ctcgattatt
      901 ctattga
//
LOCUS       DBBGRF010000166          894 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000166 DBBGRF010000000
VERSION     DBBGRF010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.177"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            253..876
                     /locus_tag="ACIZD4_003044"
     CDS             253..876
                     /locus_tag="ACIZD4_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5991874.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
BASE COUNT          329 a          129 c          167 g          269 t
ORIGIN      
        1 aaactaatgt ccttattttt gtgttcacat ttctgttacc taagaaatac ttaaaggagg
       61 tgatgtagcc agcaacgact acaacttgaa cccgctatct acagtttatt tgttgtttct
      121 tttgggtata ctctaatggt acaaatccat atttgcttaa agcgttgatt tttcagcggt
      181 ttttctttat tgcaaagtgt accctaagac ctgtatacta atagtaaata gattggatag
      241 gaatgatggc aaatgtattt agcttattta agagtttctt ccgacgatca aagtttagct
      301 cggcaacata agctaattga aaattggtca gtcaaaaata atattgctga agacgattta
      361 aaaattttcg aggaaaaagt ctctggaaaa aatattgaaa acagaccaga gctgcaagag
      421 cttatttctt tcatacgtga acgagatacg attattattc ctagtcttga tcgattagca
      481 agaaatagta aagatacaaa agacttactt caattgtttc gtagtaaagg tgcttctatt
      541 gaaatattag acctaccgtc gtttaatggg gtaactgacc ctgcattaag agacttgcta
      601 acaaatttag tcatagaagt gtttagctat gttgctgaaa acgaacggaa aaaaatcaaa
      661 gagcgtcaaa aacaaggcat tgaaattgca aagaaaaatg gtcgttatac tggtaaaaag
      721 attcaatacc atgccaatgc aacaggaaaa aacaaattga tttacgatga aattgttgat
      781 ggtctgaaga aaaaagaaac tatttctaaa atagcaaaga acgcaggagt tacaagaaaa
      841 accgtttatc gagtaaaaag agatttagga atgtaatatg ttccagttag aaag
//
LOCUS       DBBGRF010000167          882 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000167 DBBGRF010000000
VERSION     DBBGRF010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.178"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            51..>882
                     /locus_tag="ACIZD4_003045"
     CDS             51..>882
                     /locus_tag="ACIZD4_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC5991875.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     V"
BASE COUNT          305 a          155 c          168 g          254 t
ORIGIN      
        1 tgctacactc aaaatagttc cgaccaaaga attataagga gtgagtacaa atgacctata
       61 cccatcttac aacggatgaa cttgtaataa tagagtctta tttcaaaatg aatcaatctg
      121 ttgctaaaac tgcccattgc ttgaatcgtt caagacaaac gatccataaa gtatatctgt
      181 tcttcaagca aggaaaatca gccttagaat attatcaaca gtataagaaa aacaaatcaa
      241 actgtggtag acgtccgctt gttttacccg aggaacaatc agaatatatt caaagaaagg
      301 ttgttcaagg atggacaccc gatgtgattg ttggtcgtgc agcgtttcct attagttgtt
      361 ctgctcgtac catttatcgt atgttcaaaa aggggctatt tgattcttct gacttaccga
      421 tgaaaggcaa gcgtaaaccg aatggacatc aagaaagacg tggaaaacaa actttccgcc
      481 gctctattca tgaacgtgaa aaggattata gccaattctc aaatgagttt ggtcaccttg
      541 aaggtgacac tatcgtaggt ctgaaacata aaagtgctgt aattacctta gttgaacgat
      601 tatcaaaagt tatcatcaca ttgaaaccgt gtggtagaca agcgattgat attgaaaaaa
      661 aattaaatca atggtttgaa tctgtaccga aaaacctatt caaatccatc acttttgatt
      721 gtggaaagga attttcaaat tggaaacaga tcagtaatgt caatgatatt gccatttatt
      781 tcgctgatcc aggaacgccg tctcaaagag gcctaaacga gaattctaac ggattgttac
      841 gtagagatgg tttattgaaa tctatggatt tcaattcagt ag
//
LOCUS       DBBGRF010000168          867 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000168 DBBGRF010000000
VERSION     DBBGRF010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.179"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..>867
                     /locus_tag="ACIZD4_003046"
     CDS             <1..>867
                     /locus_tag="ACIZD4_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991876.1"
                     /translation="LGEIEMSYDIKIEEGSTATPFQPNLLAEPYNMCREYPNENIADH
                     TVKFPIESGDHQIYQGYTEEELMIGQTYTITLKGTKPASQTFVAYNHWTARLGELKPV
                     DGLTDVWSLTFTPTNVVASSPKLFRVYQYPQSTVGACRIDWLKIEKGDTRTPNISEYK
                     YRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTA
                     SINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREG
                     KTVSIYFVALNG"
BASE COUNT          311 a          169 c          171 g          216 t
ORIGIN      
        1 tacttgggga aatagaaatg agctatgaca tcaaaatcga agaaggctca acagctacac
       61 cattccaacc taacttatta gcagaacctt acaacatgtg tcgcgaatat cctaacgaaa
      121 atattgccga tcatacagtt aagttcccaa tcgaatctgg cgaccaccaa atatatcaag
      181 gttacacaga agaagagctt atgataggtc aaacgtatac tatcacgctt aaaggaacaa
      241 aacccgcaag tcaaaccttt gtagcgtata atcattggac tgctcgttta ggagaactaa
      301 agccagttga tgggttgaca gacgtatggt ctctaacatt cacaccaacg aatgttgtgg
      361 cgagttcacc taaacttttt cgtgtttatc agtatccaca atcaacagta ggcgcatgcc
      421 ggatcgactg gctcaagatt gaaaaaggcg acacacgaac cccgaatatt agtgagtata
      481 aatatcgtgg tactggtatg cgtgattcaa acaatccaaa agattatgtt tgggatctag
      541 caccagaata tgtcgaagat aacttggcca cagatattaa aatttctgaa attactggta
      601 aagcaaacaa ttataccgat gggaaagtat cggagattaa ttcgcagttg actgcttcaa
      661 ttaatgaagt agacaccaca gctaaggatg ctcaaacaaa agcgaatgct aatgcgactg
      721 ctatagatga attagacaat aagatcgatg aacgcattaa tgatacagct actaccacat
      781 taacagttac aaacgggaat accggatcag caaagcttta tcgtgaagga aaaacagttt
      841 ctatatattt tgtggcttta aacggaa
//
LOCUS       DBBGRF010000169          862 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000169 DBBGRF010000000
VERSION     DBBGRF010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.180"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(310..609)
                     /locus_tag="ACIZD4_003047"
     CDS             complement(310..609)
                     /locus_tag="ACIZD4_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HGC5991877.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(615..845)
                     /locus_tag="ACIZD4_003048"
     CDS             complement(615..845)
                     /locus_tag="ACIZD4_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991878.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENNQ
                     PVIAKKETVLSEGKIKTRYILEVETKFKNRSE"
BASE COUNT          290 a          147 c          117 g          308 t
ORIGIN      
        1 attgtgagat aataataaag aagagtttaa agcgcacctc aaaccacttc cccataagtg
       61 tgttacgctt taaactcttt tatatttgaa gctattaaaa ggcataccat atttttgaaa
      121 aaaagtgaga aaaaaggctt acaattggag tggtagttaa ttagtgactt atttttgatt
      181 ttatagcact gatactataa aatatagata tcatcatatt acacaatctt aatactaact
      241 taaaaaatat ctcctttcac aagtatggtg ataaaattcg ttccgggcta cctttttagg
      301 tagcctactt taatctttat acctttctgg atcaacgaaa gtatacttta tatagtcata
      361 acgccgatga tcgctacgtg cgtccggcac gtcagtcacg atatcaaaca aaaagtatac
      421 atctttcttc attctagttt ttgcagcagg gattttaaag tagttcttat tagaatagta
      481 gagattgatt aataagctat cttcgattgc tagaaagaaa acttctgaat cccacacctt
      541 ataaaaatct ttgataaatc tattcgaagg atcaaattta aaccataatt gtgtctcatt
      601 aaaaagcata gccattactc cgatctattt ttaaacttag tttctacctc taatatatat
      661 cgagttttta ttttgccttc agataatact gtttcttttt tcgcaattac aggttggtta
      721 ttttcggaaa aagctaatat agctaagatt gaaacatcca tctggaattt atcttttttg
      781 ctgctttgct cataaaagtc tgcatattca tcactgatat tttttctaat aaagtcttcc
      841 atcataaaaa tcacctcaaa ac
//
LOCUS       DBBGRF010000170          823 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000170 DBBGRF010000000
VERSION     DBBGRF010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.182"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..>823
                     /locus_tag="ACIZD4_003049"
     CDS             <1..>823
                     /locus_tag="ACIZD4_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGC5991879.1"
                     /translation="RGGWKETLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSES
                     LAIDILTFLTGISSRDGEKFPVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIAD
                     HIESFTDYDFAHLLFSDGSITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSV
                     SMLIVISTFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYF
                     VTQNSDDLLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT          253 a          142 c          186 g          242 t
ORIGIN      
        1 cgaggagggt ggaaagaaac cttgccagaa attgcggatg aaatcagtat cctcaacttg
       61 acgagtaagt cagaaaatca aggtctgctt gatccttatg tgattatgaa gaaaaagaaa
      121 gactcggaaa gtttagcaat tgatattctg acttttttaa caggaatttc aagtcgagac
      181 ggggagaagt ttcctgtgtt acgtaaagcc attcgaacgg tgactcaaag tgatcaacgg
      241 gggttattac aagttattaa cgaattgcga aaagacgggt caccaatcgc ggaaaatatc
      301 gccgatcata tcgagtcctt taccgattat gattttgctc atttgctttt ctcagacggc
      361 tcgattaccc aatcgattag tttagataaa cagctaaata tcattcaagt ggcggatttg
      421 gttttaccgg atgcagaaac gacttttgaa gaatatacca ccatggaatt gcttagtgtt
      481 tcgatgctaa tcgtcatttc cacttttgcc ttggacttta tccatagtaa ccgagaaatc
      541 ttcaaaattg tcgatttgga tgaggcttgg agttttcttc aagtggctca aggaaaaacg
      601 ttatcgaata agcttgttcg tgctggtcgg gccatgaatg ctggggtcta tttcgtcact
      661 caaaatagcg acgatttatt agatgaacgt ttaaaaaata atatcgggtt gaagtttgct
      721 tttcgcagta ccgatattca tgaaatcaag aaaaccttgg aattctttgg tttggatcag
      781 gaggatcaaa gcaatcaaaa acgcctgcga gatttggaaa acg
//
LOCUS       DBBGRF010000171          795 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000171 DBBGRF010000000
VERSION     DBBGRF010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.183"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..778)
                     /locus_tag="ACIZD4_003050"
     CDS             complement(<1..778)
                     /locus_tag="ACIZD4_003050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991880.1"
                     /translation="MSYDIKIEEGSTATPYQPNLLDDSYWLGKTPLGENLITNAKFPI
                     ITRSNPISGFDISEELIIGETYTVSLKGTKPATKEFHLYYGEANYQQLQYQATLLPVE
                     GLTDVWSATFTARNTSETTNLLRVALWQKPNSATYDTVQIDWLKIEKGDTRTPNISQF
                     KYFGEGLKDSNNPNDYSWDVTPEYTEKSLNNTVSLTEPQSIEGLKNFEDGIQSKGKSV
                     LTSDDNKYEVVTLTVTNGNTGSAKLYREGKTVTIYFFALNG"
BASE COUNT          205 a          157 c          145 g          288 t
ORIGIN      
        1 tcccattcaa cgcaaaaaaa taaatagtga cggtttttcc ttcacgataa agctttgctg
       61 atccggtatt cccgtttgta actgttaagg ttacgacttc atatttgttg tcgtctgatg
      121 tcaatacaga ttttcctttt gattgaatac catcttcgaa atttttcaat ccttcgatgg
      181 attgcggttc agtcagacta accgtattat tcaagctttt ttcagtatac tctggtgtga
      241 catcccagct gtagtcgttc ggattgttac tgtctttcaa gccttcacca aagtatttaa
      301 actgactgat atttggtgtg cgtgtgtcgc ctttttcaat cttgagccag tcaatttgaa
      361 cagtatcata tgttgcagaa ttaggttttt gccataacgc tactctaagt aaatttgtcg
      421 tttcactagt atttctggct gtaaaagtgg cactccacac atctgttaat ccttccacag
      481 gaagtaaagt tgcctgatac tgcaactgct ggtaatttgc ttctccgtag tataagtgga
      541 attctttagt agctggctta gtccctttta aagataccgt ataagtttca cctattatta
      601 attcttctga aatatcaaaa ccagaaatag gattgcttcg tgttataatt gggaacttgg
      661 cattcgttat caaattctca cccaacggtg ttttacctag ccagtaagag tcatcaagta
      721 agttaggctg atatggtgta gctgtagagc cttcttcgat tttgatgtca tagctcattt
      781 ctatttcccc aagta
//
LOCUS       DBBGRF010000172          787 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000172 DBBGRF010000000
VERSION     DBBGRF010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.184"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..716
                     /locus_tag="ACIZD4_003051"
     CDS             <1..716
                     /locus_tag="ACIZD4_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HGC5991881.1"
                     /translation="KKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTST
                     ESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADK
                     SAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWS
                     ESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNE
                     TANNELKNGFNQIVYGQAN"
BASE COUNT          282 a          151 c          159 g          195 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 cttttat
//
LOCUS       DBBGRF010000173          741 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000173 DBBGRF010000000
VERSION     DBBGRF010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.185"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..>741)
                     /locus_tag="ACIZD4_003052"
     rRNA            complement(<1..>741)
                     /locus_tag="ACIZD4_003052"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          150 a          231 c          164 g          196 t
ORIGIN      
        1 ggaagctcta tctctagagt ggtcaaagga tgtcaagacc tggtaaggtt cttcgcgttg
       61 cttcgaatta aaccacatgc tccaccgctt gtgcgggccc ccgtcaattc ctttgagttt
      121 caaccttgcg gtcgtactcc ccaggcggag tgcttaatgc gttagctgca gcactgaagg
      181 gcggaaaccc tccaacactt agcactcatc gtttacggcg tggactacca gggtatctaa
      241 tcctgtttgc tccccacgct ttcgagcctc agcgtcagtt acagaccaga gagccgcctt
      301 cgccactggt gttcctccat atatctacgc atttcaccgc tacacatgga attccactct
      361 cctcttctgc actcaagtct cccagtttcc aatgaccctc cccggttgag ccgggggctt
      421 tcacatcaga cttaagaaac cgcctgcgct cgctttacgc ccaataaatc cggacaacgc
      481 ttgccaccta cgtattaccg cggctgctgg cacgtagtta gccgtggctt tctggttaga
      541 taccgtcaag ggatgaacag ttactctcat ccttgttctt ctctaacaac agagttttac
      601 gatccgaaaa ccttcttcac tcacgcggcg ttgctcggtc agactttcgt ccattgccga
      661 agattcccta ctgctgcctc ccgtaggagt ttgggccgtg tctcagtccc aatgtggccg
      721 atcaccctct caggtcggct a
//
LOCUS       DBBGRF010000174          739 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000174 DBBGRF010000000
VERSION     DBBGRF010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.186"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..672
                     /locus_tag="ACIZD4_003053"
     CDS             <1..672
                     /locus_tag="ACIZD4_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HGC5991882.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          274 a          108 c          140 g          217 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagta
//
LOCUS       DBBGRF010000175          722 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000175 DBBGRF010000000
VERSION     DBBGRF010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.187"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..>722
                     /locus_tag="ACIZD4_003054"
     CDS             <1..>722
                     /locus_tag="ACIZD4_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HGC5991883.1"
                     /translation="KTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDV
                     IIGRKERPVSCGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRP
                     DNYPDFNSEFGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQW
                     FSRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRN
                     GLPKSMDFRKVNQTFISSVSNQR"
BASE COUNT          244 a          135 c          136 g          207 t
ORIGIN      
        1 aagactgctc ttgattattg gcaccagtat aaagaaaata agaaaaaatg tggtagaaaa
       61 gtcattcaat tacctgctca tgaagtagat tacattaaag agaaagtcac tcttggttgg
      121 acgcctgacg tcattatcgg gcgaaaagaa aggcctgttt catgcggtat gagaacactt
      181 tatcgtttat tttctaaagg aatatttgat attgacacac taccgatgaa aggtaaaaga
      241 aaacccaatg gccatcagga aaaacgggga aaacaacagt atcagcgctc aatccatgat
      301 cgacctgata attatcctga tttcaattct gagtttggtc accttgaagg tgatacgatc
      361 gttggcattc atcataaaag tgccgtcatt actttagttg aaagattatc taaagtcatt
      421 atcacgatta aacccaacgg ccgtaaggca ttagatattg aaactgccct taatcaatgg
      481 ttttctcgct tccctaaaaa cttctttaaa tctattacgt ttgactgtgg aaaagaattt
      541 tctaactgga aagccattag taaccaacat gatattgata tatattttgc ggaccctgga
      601 acaccttctc aacgcccatt aaacgagaat tctaacggga ttctgcgtcg taatggactg
      661 ccgaaatcaa tggattttag aaaagtgaat cagacattta tttccagtgt cagcaatcaa
      721 cg
//
LOCUS       DBBGRF010000176          711 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000176 DBBGRF010000000
VERSION     DBBGRF010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.188"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..375
                     /locus_tag="ACIZD4_003055"
     CDS             <1..375
                     /locus_tag="ACIZD4_003055"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991884.1"
                     /translation="DDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPD
                     GKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACHVYEK
                     LGGKNDYKDEIVYVYDYEKGDK"
     gene            376..>711
                     /locus_tag="ACIZD4_003056"
     CDS             376..>711
                     /locus_tag="ACIZD4_003056"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991885.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGI"
BASE COUNT          285 a           53 c          125 g          248 t
ORIGIN      
        1 gatgataata tggtttttga tattgataat ttaaaaggat ttcttaatga taccagttca
       61 tttgggttta tagctaaaga aaataataaa attataggat ttgcatattg ctatacactt
      121 ttaagacctg atggaaaaac aatgttttat ttacactcaa taggaatgtt acctaactat
      181 caagacaaag gttatggttc aaaattatta tcttttatta aggaatattc taaagagatt
      241 ggttgttctg aaatgttttt aataactgat aaaggtaatc ctagagcttg ccatgtatat
      301 gaaaaattag gtggtaaaaa tgattataaa gatgaaatag tatatgtata tgattatgaa
      361 aaaggtgata aataaatgaa tatagttgaa aatgaaatat gtataagaac tttaatagat
      421 gatgattttc ctttgatgtt aaaatggtta actgatgaaa gagtattaga attttatgat
      481 ggtagagata aaaaatatac attagaatca ttaaaaaaac attatacaga gccttgggaa
      541 gatgaagttt ttagagtaat tattgaatat aacaatgttc ctattggata tggacaaata
      601 tataaaatgt atgatgagtt atatactgat tatcattatc caaaaactga tgagatagtc
      661 tatggtatgg atcaatttat aggagagcca aattattgga gtaaaggaat t
//
LOCUS       DBBGRF010000177          696 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000177 DBBGRF010000000
VERSION     DBBGRF010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.189"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..249
                     /locus_tag="ACIZD4_003057"
     CDS             <1..249
                     /locus_tag="ACIZD4_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991886.1"
                     /translation="RNLLTNEELAWDQDDLGNHVTIWDHVYLIHLSKHSNKPEYIYVI
                     EDGLIDALEEYDRDNLIDISYYGPGKKYIAEMEAEFDE"
     gene            242..>696
                     /locus_tag="ACIZD4_003058"
     CDS             242..>696
                     /locus_tag="ACIZD4_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HGC5991887.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDT"
BASE COUNT          241 a          112 c          141 g          202 t
ORIGIN      
        1 cgaaatcttt tgacgaatga agaactagct tgggatcaag atgatttagg caaccatgta
       61 actatttggg atcatgttta tcttatccat ctatcgaagc attcgaataa acctgaatat
      121 atttacgtca tcgaagatgg cttgattgat gcgctagaag agtacgacag agataacttg
      181 attgatatct cttattacgg accaggtaag aaatacattg ctgaaatgga ggcagaattt
      241 gatgagtgaa atcaaaggga caacgaactt tgaaaaactt tttagtcgta agttaaataa
      301 aattctcaag aaaaaaggaa attttgatta tttatcttgg gctcacgcgt gggagattat
      361 gaaaaagaat gatccacagg caacggtaac tattaatgag tacaaacact acagggttgt
      421 ttctggaact catcaagact ttcttgttga ggaatataaa ccttttctta tggatgaaac
      481 tgggacttat gtatctgtct cagtaacggt taaaggacac acggaaaccg aattatttcc
      541 tgttttagat tatcgaaacc aaccagttgt taaaccaaat gcaatgcaaa tcaataactc
      601 attgaagcga tgctttgtga aagcattggc tctacacgga ctgggattat atgtatttca
      661 aggggaagat attccaacac cacctagaat cgatac
//
LOCUS       DBBGRF010000178          696 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000178 DBBGRF010000000
VERSION     DBBGRF010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.190"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            1..249
                     /locus_tag="ACIZD4_003059"
                     /pseudo
     CDS             1..249
                     /locus_tag="ACIZD4_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375509.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            242..>696
                     /locus_tag="ACIZD4_003060"
     CDS             242..>696
                     /locus_tag="ACIZD4_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HGC5991888.1"
                     /translation="MSENKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDT"
BASE COUNT          245 a          110 c          137 g          204 t
ORIGIN      
        1 cgaaatcttt tgacgaatga agaactagct tgtgatcaag atgatttagg taaccttgta
       61 actatttgag atcatgttta tcttatccat ttatcgaagc attcgaataa acctgaatat
      121 atttacgtca tcgaagatgg cttgattgat gcattagaag agtacgaaag ggataacttg
      181 atcgatatct cttattacgg accaggtaag aaatacattg ctgaattgga ggcagaattt
      241 gatgagtgaa aacaaaggga caacgaattt tgaaaaactt tttagtcgca agttaaataa
      301 aattctcaag aaaaaaggaa attttgatta tttatcttgg gctcacgcat gggagattat
      361 gaaaaagaat gatccacagg caacagtaac tattaatgag tacaaacact acagagttgt
      421 ttctggaact catcaagact ttcttgttga ggaatacaaa ccttttctta tggatgaaac
      481 agggacttat gtatctgtct cagtaacggt taaaggacac acggaaaccg agttatttcc
      541 tgttttagat tatcgaaacc aaccagttgt taaaccaaat gcaatgcaaa tcaataactc
      601 attgaagcga tgctttgtga aagcattggc tctacacgga ctgggattat atgtatttca
      661 aggggaagat attccaacac cacctagaat cgatac
//
LOCUS       DBBGRF010000179          683 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000179 DBBGRF010000000
VERSION     DBBGRF010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.191"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            10..>683
                     /locus_tag="ACIZD4_003061"
     CDS             10..>683
                     /locus_tag="ACIZD4_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HGC5991889.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPPFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKG"
BASE COUNT          224 a          124 c          144 g          191 t
ORIGIN      
        1 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
       61 caatttgcga tgcttacgat tgatgatcta gttcctcaag atcatctcgt tcgaaagatt
      121 gatgccgcgc ttgattttga atttatttat ccaatcgtcg aagccactta ctccgattta
      181 ggtcgcccaa gtatcgatcc agtgattctg atcaaattgg tgtttattca gtatttattc
      241 ggtatccgtt ccatgcgaca aaccattaag gaagtcgata ccaatgtcgc ttaccgctgg
      301 tttttaggct actccttcga ggagaaaatc ccccctttct caacttttgg aaagaattat
      361 gttcgccgat ttagagaaac gacggtgttt gaggatattt ttgcctatat tttagaacaa
      421 gcagttaaag caggttttgt aacagaggat aatttgtatc tggattctac ccacatcaaa
      481 gctaacgcca ataaacataa gtttacgaaa gaaatgaccc atgatgaagc gaaagcctat
      541 caggatgaat tagaagatga gatcaatcgt caacgaatag aggctggaaa acgccctttt
      601 actttggact tagaaaagga agtgaagctg aaagaaagaa aaataagtaa agctgatccg
      661 gaaagcggct actacgtcaa agg
//
LOCUS       DBBGRF010000180          664 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000180 DBBGRF010000000
VERSION     DBBGRF010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.192"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            51..>664
                     /locus_tag="ACIZD4_003062"
     CDS             51..>664
                     /locus_tag="ACIZD4_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HGC5991890.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTR"
BASE COUNT          244 a          110 c          131 g          179 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccacgatt aaaggcatgg aagccattcg aggattatat aagaaaaccc
      661 gaaa
//
LOCUS       DBBGRF010000181          595 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000181 DBBGRF010000000
VERSION     DBBGRF010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.193"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..580
                     /locus_tag="ACIZD4_003063"
     CDS             <1..580
                     /locus_tag="ACIZD4_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGC5991891.1"
                     /translation="GIKSHLWVTQNIWGDHTDPCGYLSEMGVSKEKLAYDLAHGFTDD
                     NPTTSDDNPTTSEDKPVIDPTRAGAANSTLTDGTNYAHVDQFGEIENANLHVAGWHIA
                     NYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVY
                     VMMRATNDPEGNTKGGAQDFHDKRWYLNIPQR"
BASE COUNT          204 a          106 c          122 g          163 t
ORIGIN      
        1 aggaatcaaa tcgcatttat gggtaacaca aaatatttgg ggcgatcata cagatccttg
       61 cggttatctt tctgaaatgg gtgtaagtaa agaaaaacta gcctatgatt tggctcatgg
      121 ttttacggat gataatccaa ctacttcgga tgataatcca actacttcgg aggataaacc
      181 agtaattgat ccaactcgag caggtgctgc aaattctacg ctgacagatg gaacaaatta
      241 cgcccacgtt gatcagttcg gagaaatcga aaacgcaaac ttgcatgtag ctggatggca
      301 cattgctaat tataaatacg agtatatttt cattatggac tacaatactg gaaaagaact
      361 agctagagta agagctgatg ggatttatag accagacgta aatcaagctt ataatacttt
      421 aggaaatgtt ggctatcatg tatctttcaa tatgcgtgat ttccctaata agaaagtata
      481 cgtcatgatg cgtgcgacaa acgatccaga aggaaatact aagggtggag cacaagattt
      541 tcatgacaag cgttggtatt taaatattcc acaacgataa aaaattcccc cctct
//
LOCUS       DBBGRF010000182          583 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000182 DBBGRF010000000
VERSION     DBBGRF010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.194"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            87..>583
                     /locus_tag="ACIZD4_003064"
     CDS             87..>583
                     /locus_tag="ACIZD4_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HGC5991892.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          221 a          106 c           94 g          162 t
ORIGIN      
        1 taaatgaaaa aatccataca aaaaaggaag tcccttctgt agaataaagt taacgacaac
       61 caattcacag aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc
      121 tagtcactaa aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca
      181 cactcctacg gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt
      241 ttaattcagg taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg
      301 aattaacatt ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag
      361 cctacaaaag aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg
      421 ttacgatgtc tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac
      481 aaaccatgtc caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag
      541 ccttaaatga taagtatgtc gctattttta tggacgctac tta
//
LOCUS       DBBGRF010000183          539 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000183 DBBGRF010000000
VERSION     DBBGRF010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.195"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..506
                     /locus_tag="ACIZD4_003065"
     CDS             <1..506
                     /locus_tag="ACIZD4_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HGC5991893.1"
                     /translation="YLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDIW
                     LRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVKY
                     LNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEIK
                     VLMGITA"
BASE COUNT          183 a           99 c          114 g          143 t
ORIGIN      
        1 attatctttg gaagaagaaa aatagacaat ccttctattc atggaaaatg gacgaaacct
       61 atatcaaaat taagggacgt tggcattatc tttatcgtgc aattgatgcg gacggcttaa
      121 ccttagatat ctggttacga aagaaacggg atacgcaagc agcctatgct ttcttaaaac
      181 gactccataa acagtttggt gagccgaaag caattgtgac cgataaagca ccttctcttg
      241 gctccgcctt tagaaagtta cagagtgtgg gtttatatac taagacagag caccgaactg
      301 tgaagtatct taacaattta atagaacaag accatcgacc tattaaacga cgaaataaat
      361 tttatcaaag tctccgtaca gcctcttcca cgattaaggg catggagacc attcgaggaa
      421 tatataaaaa gaaccgaaga aatggaacgc tcttcggctt ttcggtgtct actgaaatca
      481 aggtattaat gggaataaca gcctaagata tttggagttc agagagggcg cgtttgatt
//
LOCUS       DBBGRF010000184          530 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000184 DBBGRF010000000
VERSION     DBBGRF010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.196"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            105..404
                     /locus_tag="ACIZD4_003066"
     CDS             105..404
                     /locus_tag="ACIZD4_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991894.1"
                     /translation="MKKPTLSELIEAAEKAVKPDDWYRQSLILEKFHGMSKTTLVEYC
                     KEMETIPEFAEGILRPGHSTTFIHYHTFIWFLKWKDANKYRVKSLSPSDILKEAS"
BASE COUNT          186 a           87 c          115 g          142 t
ORIGIN      
        1 agggaggtaa agtcgttgga agataaaatc attcttacaa aatcagagct tcaagaaatg
       61 ttaaacatcg agtatggaac gataattttt aggagggata ataagtgaaa aaaccaacac
      121 tttcagagct gatagaagct gctgagaagg cagtaaaacc agacgactgg taccgacaaa
      181 gtttaatctt ggagaagttc cacggcatgt caaaaactac tttagttgaa tactgcaagg
      241 aaatggaaac aattcctgaa tttgcagaag gaatacttcg tccaggtcac tcaaccacat
      301 ttattcatta ccatactttt atttggtttt taaagtggaa agacgcaaac aaatatcgtg
      361 taaaaagttt atcgccttca gatattttga aggaggcaag ctaatgggca aattcaacag
      421 agcactagta ttcagcgcac cactaatcat ctacgcttta ggactttggg gaagcaaaca
      481 agcgttgata gggacaatcg tttacatggt ttggattttt atggggcttg
//
LOCUS       DBBGRF010000185          528 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000185 DBBGRF010000000
VERSION     DBBGRF010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.197"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(5..90)
                     /locus_tag="ACIZD4_003067"
     tRNA            complement(5..90)
                     /locus_tag="ACIZD4_003067"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="ACIZD4_003068"
     tRNA            complement(107..178)
                     /locus_tag="ACIZD4_003068"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="ACIZD4_003069"
     tRNA            complement(190..262)
                     /locus_tag="ACIZD4_003069"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="ACIZD4_003070"
     tRNA            complement(280..361)
                     /locus_tag="ACIZD4_003070"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="ACIZD4_003071"
     tRNA            complement(369..441)
                     /locus_tag="ACIZD4_003071"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="ACIZD4_003072"
     tRNA            complement(445..517)
                     /locus_tag="ACIZD4_003072"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DBBGRF010000186          514 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000186 DBBGRF010000000
VERSION     DBBGRF010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.198"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..132)
                     /locus_tag="ACIZD4_003073"
     CDS             complement(<1..132)
                     /locus_tag="ACIZD4_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGC5991895.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DBBGRF010000187          511 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000187 DBBGRF010000000
VERSION     DBBGRF010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.199"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..342
                     /locus_tag="ACIZD4_003074"
     CDS             <1..342
                     /locus_tag="ACIZD4_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991896.1"
                     /translation="DNIRDKKASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDL
                     IRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRA
                     SLYRKLSEVNN"
BASE COUNT          206 a           68 c           93 g          144 t
ORIGIN      
        1 gataacatac gagataaaaa ggcaagttta aaatcactaa aagatacatg gcttgattta
       61 tcagaagata atccatacag ccaattctta attactgtaa tggctggtgt taaccaatta
      121 gagcgagatc ttattcggat gagacaacgt gaagggattg aattggctaa gaaagaagga
      181 aagtttaaag gtcgattaaa gaagtatcat aaaaatcacg caggaatgaa ttatgcggta
      241 aagctatata aagaaggaaa tatgactgta aatcaaattt gtgaaattac taatgtatct
      301 agggcttcat tatacaggaa attatcagaa gtgaataatt agccattctg tattccgcta
      361 atgggcaata tttttaaaga agaaaaggaa actataaaat attaacagcc tcctagcgat
      421 gccgaaaagc cctttgataa aaaaagaatc atcatcttaa gaaattctta gtcatttatt
      481 atgtaaatgc ttataaattc ggccctataa t
//
LOCUS       DBBGRF010000188          506 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000188 DBBGRF010000000
VERSION     DBBGRF010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.200"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..>506
                     /locus_tag="ACIZD4_003075"
     CDS             <1..>506
                     /locus_tag="ACIZD4_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HGC5991897.1"
                     /translation="DLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFS
                     RIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLK
                     VEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELG
                     CANASEAV"
BASE COUNT          153 a           89 c          110 g          154 t
ORIGIN      
        1 agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca ttttggatct
       61 gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg ttctagtaaa
      121 aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc atactgatcg
      181 tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg acatcaatcg
      241 atcattgagt cataaaggct gtccttttga taatgccgta gctgaatcaa cttataagtc
      301 gttgaaagta gaatttgtct atcaatacac atttgaaacc ttacaacaat tggatttgga
      361 gttatttgac tatgtcaatt ggtggaacca ccttcggttg cacggtacac ttggctacga
      421 gacaccggtt ggttaccgta accagagatt ggcgcagcga atccttgata atgagctcgg
      481 atgtgctaac gctagcgagg cagtct
//
LOCUS       DBBGRF010000189          498 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000189 DBBGRF010000000
VERSION     DBBGRF010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.201"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            207..>498
                     /locus_tag="ACIZD4_003076"
     CDS             207..>498
                     /locus_tag="ACIZD4_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HGC5991898.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIK"
BASE COUNT          190 a           60 c          101 g          147 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaac
//
LOCUS       DBBGRF010000190          490 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000190 DBBGRF010000000
VERSION     DBBGRF010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.202"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            149..388
                     /locus_tag="ACIZD4_003077"
     CDS             149..388
                     /locus_tag="ACIZD4_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HGC5991899.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
BASE COUNT          204 a           58 c           94 g          134 t
ORIGIN      
        1 tctttctcaa aataaacata aaagcccttt aaagagggct tttatatatt aatcacaaat
       61 cacttatcac aaatcactta tcacaaatca caagtgattt gtgattgttg atgataaaat
      121 aagaataaga agaaatagaa agaagtgagt gattgtggga aatttaggcg cacaaaaaga
      181 aaaacgaaat gatacaccaa tcagtgcaaa aaaagatata atgggagata agacggttcg
      241 tgttcgtgct gacttgcacc atatcataaa aatcgaaaca gcaaagaatg gcggaaacgt
      301 aaaagaagtt atggaaataa gacttagaag caaacttaag agtgtgttga tagtgcatta
      361 tcttaaaatt ttgtataata ggaattgaag ttaaattaga tgctaaaaat ttgtaattaa
      421 gaaggaggga ttcgtcatgt tggtattcca aatgcgtaat gtagataaaa catctactgt
      481 tttgaaacag
//
LOCUS       DBBGRF010000191          487 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000191 DBBGRF010000000
VERSION     DBBGRF010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.203"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..>487)
                     /locus_tag="ACIZD4_003078"
     CDS             complement(<1..>487)
                     /locus_tag="ACIZD4_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991900.1"
                     /translation="VFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAFS
                     LLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRY
                     NYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKP
                     F"
BASE COUNT          184 a           78 c           62 g          163 t
ORIGIN      
        1 aaaaacggct ttccaaatga tgaaatacct aaatctaact tattaagaaa gttgaaattt
       61 ttatattcag gaaaccattt attaatttca tgtgcagcac gtaatgcatt ccctggagtt
      121 gtcaaagaga aaattaattc tgctaagctt attattgaaa atactgataa cttataatta
      181 tatcgtccat tgacaatcaa atataaacta actatacttg ttagaacaaa aaaacaggcg
      241 ttgacttgtt cttgattagt taaaaatatc aataaaggaa tacttaccca atatattttt
      301 ctatttattt cttctcctct taagagttga aaaaacggat aaaaagttag taaactaaat
      361 gctactggcc actgatagtt caaggtggtt gctctccaac cggtttcccc cattactgtc
      421 aatggtatta aacagtatat agagcaaacc aataataaat ttttaacatt tattttctca
      481 aaaacat
//
LOCUS       DBBGRF010000192          481 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000192 DBBGRF010000000
VERSION     DBBGRF010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.204"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..>481
                     /locus_tag="ACIZD4_003079"
     CDS             <1..>481
                     /locus_tag="ACIZD4_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HGC5991901.1"
                     /translation="TFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKW
                     PEEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDL
                     PKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG
                     "
BASE COUNT          194 a           74 c          112 g          101 t
ORIGIN      
        1 taaccttcac cgcaggagaa ggaacaagta ttgaaagtgg aacaacagtc tttgcagtga
       61 aagacggcgt aagcttacca gaagataaac ttccagtgtt gaaagcaaaa gatggttata
      121 cagatgcgaa atggccagag gaagcaactc aaccaattac agcagatgat acagaatttg
      181 tatcaagtgc aacaaaactg gatgataaat ctgacgctga caaatataat cctgaaggtc
      241 aaaaagtgac tacagaattg aataaggaac cagacgcatt tgagggaatt aagaacaaag
      301 aagatttacc aaaagatact aagtatactt ggaaagaaaa agtagatgtt agcgcagctg
      361 gaaataaaaa agggactgtt gtagtgacat atccagatgg atcatctgat gaagttgaag
      421 tagatgttac agtgacagac aatcgttctg acgccgataa atatgagcca acagtagaag
      481 g
//
LOCUS       DBBGRF010000193          473 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000193 DBBGRF010000000
VERSION     DBBGRF010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.205"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            16..354
                     /locus_tag="ACIZD4_003080"
     CDS             16..354
                     /locus_tag="ACIZD4_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HGC5991902.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
BASE COUNT          169 a           63 c          110 g          131 t
ORIGIN      
        1 agggaggaac agctaatgca atatctagaa gcaaaaatcc caattccaga aggctatgta
       61 attatctccc aagtggatta tgaggagtta aaaaaagctg atgatactgg tagatggatg
      121 acgttgccag aagtgctaga acggattaac agaaaatatg attggtttac ttctagagtt
      181 ttaaagaacc caagatatag aaatattatc gatatcgaga aaaacaaaaa tggatttgtc
      241 tattatccag ttgaaggaag agacacatat ctatttttaa gaagtaaaac acttgaattt
      301 ttagaaacaa atttttcgga aatcttaagg aggcaagcgg atgggaaaat ttaatagagc
      361 gctagtgttc agcgcaccgc taatcatcta cgctttagga ctttggggaa gcaggcaagc
      421 gttgatagga acgattgttt acatggtttg gatttttatg gggcttgatg aag
//
LOCUS       DBBGRF010000194          447 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000194 DBBGRF010000000
VERSION     DBBGRF010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.206"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(204..>447)
                     /locus_tag="ACIZD4_003081"
     CDS             complement(204..>447)
                     /locus_tag="ACIZD4_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC5991903.1"
                     /translation="CASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKII
                     RIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          162 a           58 c           77 g          150 t
ORIGIN      
        1 gaattaaaaa tattaaacag gaatttatcg aaaatggtag aaaagaaatt tataaaagga
       61 cttataaaga ttgattatat aatatatgaa aagctattat aaaagacatt agtattaaat
      121 agtttaaaaa aatgaaaaat aataaaggaa gtgagtcaat tccagactcc tgtgtaaaat
      181 gctatacaat gtttttacca tttctactta tcaaaattga tgtattttct tgaagaataa
      241 atccattcat catgtaggtc cataagaacg gctccaatta agcgattggc tgatgtttga
      301 ttggggaaga tgcgaataat cttttctctt ctgcgtactt cttgattcag tcgttcaatt
      361 agattggtac tctttagtcg attgtgggaa tttccttgta cggtatattg aaaggcgtct
      421 tcgaatccat catccaatga tgcgcaa
//
LOCUS       DBBGRF010000195          437 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000195 DBBGRF010000000
VERSION     DBBGRF010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.207"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            1..437
                     /locus_tag="ACIZD4_003082"
                     /pseudo
     CDS             1..437
                     /locus_tag="ACIZD4_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612146.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          179 a           77 c           80 g          101 t
ORIGIN      
        1 atcttacgcc tgaacaaaaa gaattgttag aactacgtaa aagaaaccag caattagaaa
       61 tggaaaatga tattttaaag caagcagcgc tgatattcgg acgaagagac aagtaatcga
      121 tgcgaataag catctttacc ctatatcagc gatgtgcaga atattaggtc tatcacgtca
      181 gtcctattat tatcaatcaa aaccaaagaa agacgaatca gaacttgaag aagtagtcgc
      241 tgaagaattt atccgcagcc gaaaggccta cggctcaaga aaaataaaaa aagccttatc
      301 aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa atagaggatt
      361 aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca atgaagccaa
      421 aacgacaaac gtattga
//
LOCUS       DBBGRF010000196          430 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000196 DBBGRF010000000
VERSION     DBBGRF010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.208"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            1..430
                     /locus_tag="ACIZD4_003083"
                     /pseudo
     CDS             1..430
                     /locus_tag="ACIZD4_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          165 a           84 c           85 g           96 t
ORIGIN      
        1 aaacaacaaa tcgtcgatct ctatctcgct ggtaagcctc gcgcagaaat tattcgagag
       61 tatgagctta cgccttcttc tttcgataaa tggatgaagc aagcacaatc aacgggctca
      121 ttcaaagaaa gagacaactt aacaccagaa caagcagaat tgatcgcact aagaaagaaa
      181 aataagcaac tcgaaatgga gaatgatatt ttaaagcaag cggcgctgat attcggacga
      241 aaagacaagt aattgatgcc aacaagcata aatattccat atcagcgatg tgcaaaattc
      301 taaatatttc tcgtcaaacc tactattatc aagcgaaacc gatcgaaaat gagtccgact
      361 tagaagagat cgttcaggaa gagtttattc gaaaccgaaa ggcttacggt acccgaaaat
      421 tgaagaagtg
//
LOCUS       DBBGRF010000197          415 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000197 DBBGRF010000000
VERSION     DBBGRF010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.209"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..339)
                     /locus_tag="ACIZD4_003084"
     CDS             complement(<1..339)
                     /locus_tag="ACIZD4_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991904.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DBBGRF010000198          408 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000198 DBBGRF010000000
VERSION     DBBGRF010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.210"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..>408
                     /locus_tag="ACIZD4_003085"
     CDS             <1..>408
                     /locus_tag="ACIZD4_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HGC5991905.1"
                     /translation="CSVLFPNGDFPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELV
                     GIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSI
                     TNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          137 a           76 c           67 g          128 t
ORIGIN      
        1 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
       61 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      121 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      181 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      241 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      301 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      361 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DBBGRF010000199          363 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000199 DBBGRF010000000
VERSION     DBBGRF010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.211"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..>363
                     /locus_tag="ACIZD4_003086"
     CDS             <1..>363
                     /locus_tag="ACIZD4_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC5991906.1"
                     /translation="IHVSRNIAHKVRVKDRKEICDDFKAVYQANSKEEANTFLSGMIE
                     KWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQN
                     EESLERFLVSIFDTYNQK"
BASE COUNT          139 a           70 c           56 g           98 t
ORIGIN      
        1 gtatccatgt atctcgtaac atcgctcata aagtacgtgt caaagaccga aaagaaatct
       61 gtgatgactt taaggctgtt tatcaagcta actcaaaaga agaagcgaat accttcttat
      121 ccggcatgat tgagaaatgg aagaaaaact atcctaaagt gacgcagtca ctcatagaaa
      181 accaagactt attaactttt tatgattttc cacctagcat tcgtagaacc atttactcaa
      241 ccaatctaat cgagtctttc aataagcaaa ttaaaagata cagccgtaga aaagagcagt
      301 ttcaaaatga agaatcacta gaacgctttc tagtcagcat ttttgataca tacaatcaaa
      361 aat
//
LOCUS       DBBGRF010000200          355 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000200 DBBGRF010000000
VERSION     DBBGRF010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.212"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(170..>355)
                     /locus_tag="ACIZD4_003087"
     CDS             complement(170..>355)
                     /locus_tag="ACIZD4_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HGC5991907.1"
                     /translation="LQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKRA
                     WRKMLDDELIPLENELR"
BASE COUNT          102 a           70 c           49 g          134 t
ORIGIN      
        1 tgcaacagaa ccggtaaatg aatgaaaaag atggaagaat cattattcaa tagctttctt
       61 aaatactccg ttataaaatg tgaacaagta aaaagacatc tatccctatt ttctacactt
      121 ccactttact actatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
      181 cattttcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
      241 gtgggtattt aaatggtttc gcttctggat gtttggcttt atatccttcg taatccttac
      301 tgttgataat tgctttcata ttaggaattg gatcttcacc tggcatatat tgcag
//
LOCUS       DBBGRF010000201          321 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000201 DBBGRF010000000
VERSION     DBBGRF010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.213"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..>321)
                     /locus_tag="ACIZD4_003088"
     CDS             complement(<1..>321)
                     /locus_tag="ACIZD4_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC5991908.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSL"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DBBGRF010000202          320 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000202 DBBGRF010000000
VERSION     DBBGRF010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.214"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(34..270)
                     /locus_tag="ACIZD4_003089"
                     /pseudo
     CDS             complement(34..270)
                     /locus_tag="ACIZD4_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           99 a           49 c           55 g          117 t
ORIGIN      
        1 agaaggactg accttctgtc tcagattttt ttgttatttc acttgaatca attgattgat
       61 caaaaaaatc ctgattttca tgttctcaaa tgatttaaat ccataagata atcgtttcag
      121 tgtcttgata tggggaatct tggcctctat tttgccatta gaatacgggt aaatcatagc
      181 attgtaaata ccttcttcat acgttaaaag gttttgaagt ttcgtgcgaa gttgtgcatc
      241 aagtgtttca ggaagatttt ttaataacgc cgtttgtata attaagcgag acaaataaaa
      301 aagccattta tgttacactc
//
LOCUS       DBBGRF010000203          315 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000203 DBBGRF010000000
VERSION     DBBGRF010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.215"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
BASE COUNT          127 a           41 c           62 g           85 t
ORIGIN      
        1 aatagtgata attagtaata tacgaattat aagatacatt ttatatttaa tgtatgtaaa
       61 taaataaaat gactgacgga tattgaatag taataaataa caataattca gacggataca
      121 gtgagtgaag tagcttgcta cgaacgaaca ggcagaatga aacggtagtt tcattagagc
      181 aagtcgcttg cgacgtagcg ttaccactga tgtaactggc aagttacata gagagagttt
      241 gcttgcaaac gaacgttacc cacttgaata gaaaacaaaa ataacatatt agtgaatttt
      301 gaataggagc cacaa
//
LOCUS       DBBGRF010000204          309 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000204 DBBGRF010000000
VERSION     DBBGRF010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.216"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACIZD4_003090"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACIZD4_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HGC5991909.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           97 a           45 c           50 g          117 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatat
//
LOCUS       DBBGRF010000205          300 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000205 DBBGRF010000000
VERSION     DBBGRF010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.217"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
BASE COUNT          106 a           33 c           48 g          113 t
ORIGIN      
        1 gaggactacc tgtattagtc ctcttttttg accagatttt gaccagtcta ttttacattc
       61 taatatattc atatgagcta attttatgat taaatggtaa gtttttcctt gtttgtttta
      121 gtttaaacta gtgtgtaatt caaaaatcta tatggaagga tctgtggggt aaatcattat
      181 acaaaagtaa aattttactt attaacaggc tgtagaaata taaaaaagaa ctaaaattta
      241 actaaattat gtgctattct taaggaaagc caagtgtatg agaaagtttc tgagaatata
//
LOCUS       DBBGRF010000206          299 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000206 DBBGRF010000000
VERSION     DBBGRF010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.218"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..>299
                     /locus_tag="ACIZD4_003091"
     CDS             <1..>299
                     /locus_tag="ACIZD4_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC5991910.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT          102 a           63 c           54 g           80 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DBBGRF010000207          268 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000207 DBBGRF010000000
VERSION     DBBGRF010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.219"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..247)
                     /locus_tag="ACIZD4_003092"
     CDS             complement(<1..247)
                     /locus_tag="ACIZD4_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGC5991911.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEK"
BASE COUNT           67 a           50 c           48 g          103 t
ORIGIN      
        1 ttttttcaat gtattctttt tcctcagcag gaaaaatgat ttcggttctc ccacaacgtc
       61 gcttattttc tttgtattgt tcaaagtatt caagtgctgt tccaccacat ttgagaaagt
      121 tatagacatt gtaaattgtt tggcgtccac gtttaagctg cttcgcaacg atagcaaccg
      181 gagtttcttg atgaaaatat gcttctatca ttacaagctc gtttggtgta agatgggtat
      241 aagtcattta tgttcactct ccttgtat
//
LOCUS       DBBGRF010000208          266 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000208 DBBGRF010000000
VERSION     DBBGRF010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.220"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            85..>266
                     /locus_tag="ACIZD4_003093"
     CDS             85..>266
                     /locus_tag="ACIZD4_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGC5991912.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT           84 a           55 c           43 g           84 t
ORIGIN      
        1 tacctatgaa atattttcac gtgttaaagt attcctcgtt gaacacaaca aataaaactt
       61 tttaacgaat aaaggagatt tttcatgaca tcacttaaaa ctttactttt tggaacaact
      121 ttggctgccg gcgctgcatt cttcatggga acgactgctc atgcggacga agcttatacc
      181 gttcaatcag gtgatactct atcaacgatt tctcaaaaat acgttggtga taactccttg
      241 atcaatgcca ttgcagaatc aaattc
//
LOCUS       DBBGRF010000209          242 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000209 DBBGRF010000000
VERSION     DBBGRF010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.221"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..195
                     /locus_tag="ACIZD4_003094"
     CDS             <1..195
                     /locus_tag="ACIZD4_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HGC5991913.1"
                     /translation="TILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSY
                     EQCALMERAIAAKRKELDKK"
BASE COUNT           91 a           33 c           54 g           64 t
ORIGIN      
        1 acgattctag aagctttcaa tgagcagatg ggtaaagata tgaccaaaac cttaatcgaa
       61 tatgttaatg agcagacaga taaattaggg ctcttagctg ataacgttga aactattgaa
      121 cagttaagct atgagcaatg tgccttgatg gagcgagcaa tagcagctaa gagaaaagaa
      181 ttagataaga agtgatatga gtgtttaaac cattaatcga ttcatattca gcggttctga
      241 aa
//
LOCUS       DBBGRF010000210          235 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000210 DBBGRF010000000
VERSION     DBBGRF010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..235
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.222"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..>235)
                     /locus_tag="ACIZD4_003095"
     CDS             complement(<1..>235)
                     /locus_tag="ACIZD4_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC5991914.1"
                     /translation="PRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVK
                     GLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT           69 a           45 c           36 g           85 t
ORIGIN      
        1 atatcctaaa gaatatctca aagttccttc aaaacgtcgt tgtgctcgac ttaatagaac
       61 actgtaagcc agtaatatgc tttcaaatct actctctagc cctttaacag aacgtgagtt
      121 gaaattttga caacctaatt tttctaagga agaaaaaaca gtctcaactg tttttctttg
      181 ttttccaagt aagctgtggt ctagtttttc tgatttatcc atgtttttac gtggc
//
LOCUS       DBBGRF010000211          232 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000211 DBBGRF010000000
VERSION     DBBGRF010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.denovo.223"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..>232)
                     /locus_tag="ACIZD4_003096"
     CDS             complement(<1..>232)
                     /locus_tag="ACIZD4_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991915.1"
                     /translation="LLNDVSNYKTILRINKQRFKCKHCGKTFLAEDSVSDRRCSIARR
                     VKQAILELLSEPLSMSLIARMKHISPTTVIRIL"
BASE COUNT           70 a           42 c           53 g           67 t
ORIGIN      
        1 aagtattcga atgacagtgg tcggagaaat gtgcttcata cgtgcgatca aagacataga
       61 aagaggttcg cttaatagct caagaatggc ttgtttgact ctgcgagcaa tggagcagcg
      121 acgatcacta actgaatctt ctgctaaaaa agtctttcca cagtgtttac atttgaagcg
      181 ctgtttgtta atccgcagaa tggtcttgta gttactgaca tcattcaata ag
//
LOCUS       DBBGRF010000212        10793 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.083, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000212 DBBGRF010000000
VERSION     DBBGRF010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.083"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            260..1171
                     /locus_tag="ACIZD4_003097"
     CDS             260..1171
                     /locus_tag="ACIZD4_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HGC5991916.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACIZD4_003098"
     CDS             1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACIZD4_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HGC5991917.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            2328..2612
                     /locus_tag="ACIZD4_003099"
     CDS             2328..2612
                     /locus_tag="ACIZD4_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGC5991918.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            2978..3277
                     /locus_tag="ACIZD4_003100"
     CDS             2978..3277
                     /locus_tag="ACIZD4_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991919.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            3320..4810
                     /locus_tag="ACIZD4_003101"
     CDS             3320..4810
                     /locus_tag="ACIZD4_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HGC5991920.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            5158..5328
                     /locus_tag="ACIZD4_003102"
     CDS             5158..5328
                     /locus_tag="ACIZD4_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991921.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            5342..5959
                     /locus_tag="ACIZD4_003103"
     CDS             5342..5959
                     /locus_tag="ACIZD4_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGC5991922.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVIVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINSLVIELYKYQAESERKKIKERQAQGIEIAKKKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
     gene            5959..6897
                     /locus_tag="ACIZD4_003104"
                     /pseudo
     CDS             5959..6897
                     /locus_tag="ACIZD4_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            complement(7590..8237)
                     /locus_tag="ACIZD4_003105"
     CDS             complement(7590..8237)
                     /locus_tag="ACIZD4_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-7 chloramphenicol O-acetyltransferase"
                     /protein_id="HGC5991923.1"
                     /translation="MTFNIIELENWDRKEYFEHYFNQQTTYSITKEIDITLFKDMIKK
                     KGYEIYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWT
                     ESDKNFISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNS
                     SFLLPIITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDIIHRVDDWI"
     gene            complement(8367..9305)
                     /locus_tag="ACIZD4_003106"
     CDS             complement(8367..9305)
                     /locus_tag="ACIZD4_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGC5991924.1"
                     /translation="MKKIDEKLAAEISLKKPAVSNSRLSNSRLSGQTLGKSQPALSFD
                     AMTIVGNLNKTNAKKLSDFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWD
                     RRNMRVEFNPNKLTHEEMIWLKQNIIDYMEDDGFTRLDLAFDFEDDLSDYYAMTDKAV
                     KKTVFYGRNGKPETKYFGVRDSDRFIRIYNKKQERKDNADVEVVSEHLWRVEVELKRD
                     MVDYWNDCFNDLHILKPAWATLEKINEQAMVYTLLHEESMWGKLSKNTKTKFKKLIRE
                     ISPIDLTELMKSTLKANEKQLQKQIDFWQREFRFWK"
     gene            9796..10793
                     /locus_tag="ACIZD4_003107"
                     /pseudo
     CDS             9796..10793
                     /locus_tag="ACIZD4_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
BASE COUNT         3909 a         1671 c         1878 g         3335 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccc ccattgtcaa caggcagttc
       61 agcctcgtta aattcagcat gggtatcact tatgaaaatt catctacatt ggtgataata
      121 gtaaatccag tagggcgaaa taattgactg taatttacgg ggcaaaacgg cacaatctca
      181 aacgagattg tgccgtttaa ggggaagatt ctagaaatat ttcatacttc caactatata
      241 gttaaggagg agactgaaaa tgaagaagtt gtttttttta ttgttattgt tattcttaat
      301 atacttaggt tatgactacg ttaatgaagc actgttttct caggaaaaag tcgaatttca
      361 aaattatgat caaaatccca aagaacattt agaaaatagt gggacttctg aaaataccca
      421 agagaaaaca attacagaag aacaggttta tcaaggaaat ctgctattaa tcaatagtaa
      481 atatcctgtt cgccaagaaa gtgtgaagtc agatatcgtg aatttatcta aacatgacga
      541 attaataaat ggatacgggt tgcttgatag taatatttat atgtcaaaag aaatagcaca
      601 aaaattttca gagatggtca atgatgctgt aaagggtggc gttagtcatt ttattattaa
      661 tagtggctat cgagactttg atgagcaaag tgtgctttac caagaaatgg gggctgagta
      721 tgccttacca gcaggttata gtgagcataa ttcaggttta tcactagatg taggatcaag
      781 cttgacgaaa atggaacgag cccctgaagg aaagtggata gaagaaaatg cttggaaata
      841 cgggttcatt ttacgttatc cagaggacaa aacagagtta acaggaattc aatatgaacc
      901 atggcatatt cgctatgttg gtttaccaca tagtgcgatt atgaaagaaa agaatttcgt
      961 tctcgaggaa tatatggatt acctaaaaga agaaaaaacc atttctgtta gtgtaaatgg
     1021 ggaaaaatat gagatctttt attatcctgt tactaaaaat accaccattc atgtgccgac
     1081 taatcttcgt tatgagatat caggaaacaa tatagacggt gtaattgtga cagtgtttcc
     1141 cggatcaaca catactaatt caaggaggta aggatggcgg aatgaaacca acgaaattaa
     1201 tgaacagcat tattgtacta gcacttttgg ggtaacgtta gctttttaat ttaaaaccca
     1261 cgttaactag gacattgcta tactaatgat acaacttaaa caaaagaatt agaggaaatt
     1321 atattgggaa aaatattatc tagaggattg ctagctttat atttagtgac actaatctgg
     1381 ttagtgttat tcaaattaca atacaatatt ttatcagtat ttaattatca tcaaagaagt
     1441 cttaacttga ctccatttac tgctactggg aatttcagag agatgataga taatgttata
     1501 atctttattc catttggctt gcttttgaat gtcaatttta aagaaatcgg atttttacct
     1561 aagtttgctt ttgtactggt tttaagtctt acttttgaaa taattcaatt tatcttcgct
     1621 attggagcga cagacataac agatgtaatt acaaatactg ttggaggctt tcttggactg
     1681 aaattatatg gtttaagcaa taagcatatg aatcaaaaaa aattagacag agttattatt
     1741 tttgtaggta tacttttgct cgtattattg ctcgtttacc gtacccattt aagaataaat
     1801 tacgtgtaag atgtctaaat caagcaatct gatctttcat acacataaag atattgaatg
     1861 aattggatta gatggaaaac gggatgtggg gaaactcgcc cgtaggtgtg aagtgagggg
     1921 aaaaccggtg ataaagtaaa aagcttacct aacactatag taacaaagaa agcccaatta
     1981 tcaattttag tgctgaggaa ttggtctctt taataaattt ccttaacgtt gtaaatccgc
     2041 attttcctga cggtaccccc actagcagcc atgctttttt tgaatctttg taggacgttt
     2101 taaagagaat tacccacttt aaaattaaac atgcgcttag aatcgcttta ggaaacacga
     2161 tccagtccaa taatcgtcga taaaaacttt tgaaaaaggt tggtgaaatt acctactttt
     2221 ggaataatca caaatcacaa gtgattaatc acttgtttat taagatatta aaagctataa
     2281 tttaaataaa gcgtgaattt tattacacaa aaagaggggg gagaaacttg gaactagcat
     2341 ttagagaaag cttaaaaaag atgagaggta ccaaatcaaa agaaaaattc tcccaagaat
     2401 tagaaatgag tagatcaaat tattcacgaa tagaatcagg aaaatcagat ccaaccataa
     2461 aaacactaga acaaattgca aagttaacta actcaacgct agtagtggat ttaatcccaa
     2521 atgagccaac agaaccagaa ccagaaacag aatcagaaca agtaacattg gatttagaaa
     2581 tggaagaaga aaaaagcaat gacttcgtgt gaataatgca cgaaatcgtt gcttattttt
     2641 tttaaaagcg gtatactaga tataacgaaa caacgaactg aatagaaacg aaaaaagagc
     2701 catgacacat ttataaaatg tttgacgaca ttttataaat gcatagcccg ataagattgc
     2761 caaaccaacg cttatcagtt agtcagatga actcttccct cgtaagaagt tatttaatta
     2821 actttgtttg aagacggtat ataaccgtac tatcattata tagggaaatc agagagtttt
     2881 caagtatcta agctactgaa tttaagaatt gttaagcaat caatcggaaa tcgtttgatt
     2941 gctttttttg tattcattta tagaaggtgg agtttgtatg aatcatgatg aatgtaaaac
     3001 ttatataaaa aatagtttat tggagataag aaaattagca aatatctata cactagaaac
     3061 gtttaagaaa gagttagaaa agagaaatat ctacttagaa acaaaatcag ataagtattt
     3121 ttcttcggag ggggaagatt atatatataa gttaatagaa aataacaaaa taatttattc
     3181 gattagtgga aaaaaattga cttataaagg aaaaaaatct ttttcaaaac atgcaatatt
     3241 gaaacagttg aatgaaaaag caaaccaagt taattaaaca acctatttta taggatttat
     3301 aggaaaggag aacagctgaa tgaatatccc ttttgttgta gaaactgtgc ttcatgacgg
     3361 cttgttaaag tacaaattta aaaatagtaa aattcgctca atcactacca agccaggtaa
     3421 aagcaaaggg gctatttttg cgtatcgctc aaaatcaagc atgattggcg gtcgtggtgt
     3481 tgttctgact tccgaggaag cgattcaaga aaatcaagat acatttacac attggacacc
     3541 caacgtttat cgttatggaa cgtatgcaga cgaaaaccgt tcatacacga aaggacattc
     3601 tgaaaacaat ttaagacaaa tcaatacctt ctttattgat tttgatattc acacggcaaa
     3661 agaaactatt tcagcaagcg atattttaac aaccgctatt gatttaggtt ttatgcctac
     3721 tatgattatc aaatctgata aaggttatca agcatatttt gttttagaaa cgccagtcta
     3781 tgtgacttca aaatcagaat ttaaatctgt caaagcagcc aaaataattt cgcaaaatat
     3841 ccgagaatat tttggaaagt ctttgccagt tgatctaacg tgtaatcatt ttggtattgc
     3901 tcgcatacca agaacggaca atgtagaatt ttttgatcct aattaccgtt attctttcaa
     3961 agaatggcaa gattggtctt tcaaacaaac agataataag ggctttactc gttcaagtct
     4021 aacggtttta agcggtacag aaggcaaaaa acaagtagat gaaccctggt ttaatctctt
     4081 attgcacgaa acgaaatttt caggagaaaa gggtttaata gggcgtaata acgtcatgtt
     4141 taccctctct ttagcctact ttagttcagg ctattcaatc gaaacgtgcg aatataatat
     4201 gtttgagttt aataatcgat tagatcaacc cttagaagaa aaagaagtaa tcaaaattgt
     4261 tagaagtgcc tattcagaaa actatcaagg ggctaatagg gaatacatta ccattctttg
     4321 caaagcttgg gtatcaagtg atttaaccag taaagattta tttgtccgtc aagggtggtt
     4381 taaattcaag aaaaaaagaa gcgaacgtca acgtgttcat ttgtcagaat ggaaagaaga
     4441 tttaatggct tatattagcg aaaaaagcga tgtatacaag ccttatttag tgacgaccaa
     4501 aaaagagatt agagaagtgc taggcattcc tgaacggaca ttagataaat tgctgaaggt
     4561 actgaaggcg aatcaggaaa ttttctttaa gattaaacca ggaagaaatg gtggcattca
     4621 acttgctagt gttaaatcat tgttgctatc gatcattaaa gtaaaaaaag aagaaaaaga
     4681 aagctatata aaggcgctga caaattcttt tgacttagag catacattca ttcaagagac
     4741 tttaaacaag ctagcagaac gccctaaaac ggacacacaa ctcgatttgt ttagctatga
     4801 tacaggctga aaataaaacc cgcactatgc cattacattt atatctatga tacgtgtttg
     4861 ttttttcttt gctgtttagc gaatgattag cagaaatata cagagtaaga ttttaattaa
     4921 ttattagggg gagaaggaga gagtagcccg aaaactttta gttggcttgg actgaacgaa
     4981 gtgagggaaa ggctactaaa acgtcgaggg gcagtgagag cgaagcgaac acttgatttt
     5041 ttaattttct atcttttata ggtcattaga gtatacctat ttgtcctaat atgattttag
     5101 cagtataatt gacttggtga ataggtcatt taagttgggc ataataggag gagtaaaatg
     5161 aaaaaattta tttatcgagt tttagaaaat gacgaagtgg tggctatttt taatgagcaa
     5221 caatatgcgc aagattttat cgcttacgaa aagacaattt ctgataagca atttgaaatt
     5281 gaaaaagtag atattgctga ttggttattg caaccgagag aattttagag gttggttgaa
     5341 aatggctaaa attggttatg cacgtgtcag tagcaaagaa cagaacttag atcggcaatt
     5401 acaagcgtta cagggcgttt ctaaggtctt ttcagacaaa ttaagcggtc aatcggtcga
     5461 acgcccacaa ttacaagcta tgcttaacta tattcgtgaa ggggatattg ttattgttac
     5521 tgaattagat cgattaggac gaaataataa agaattaaca gaattgatga atcaaattca
     5581 aattaagggg gcaaccctgg aagtcttaaa tttaccctca atgaatggta ttgaagatga
     5641 aaatttaagg cgtttgatta atagccttgt cattgaattg tacaagtatc aagcagaatc
     5701 agaacgaaaa aaaattaagg aacgtcaggc acaaggaatc gaaattgcta agaaaaaagg
     5761 caaattcaaa ggtcgtcagc ataaatttaa agaaaatgat ccacgtttaa agcatgcttt
     5821 cgatttgttt ttgaatggtt tatccgataa agaagttgaa gaacaaactg gaatcaatcg
     5881 ccgaacgttt agaaggtatc gagcaagata taacgtgaca gtcgatcaaa gaaaaaacaa
     5941 tgaaaagagg gatagttaat gagtacggtt attttagctg aaaaaccaag ccaggcatta
     6001 gcctacgcaa gtgctttaaa acaaagcacc aaaaaagacg gttattttga gatcaaagac
     6061 ccactattta cagatgaaac gtttatcacc tttggttttg ggcatttagt ggaattagca
     6121 gaaccaggtc attatgacga aaagtggcaa aattggaaac ttgaatcttt gccgattttt
     6181 cctgatcgat acgattttga agttgcaaaa gataagggaa agcagtttaa aattgttgca
     6241 gaacttctca aaaaggcaaa tacaattatt gttgcaacag atagcgacag agaaggtgaa
     6301 aatatcgcct ggtcgattat ccataaagca aatgcctttt caaaagataa aacatttaaa
     6361 agactatgga tcaatagctt agaaaaagat gtaatccgaa gcggttttca aaatttgcaa
     6421 cctggaatga attactatcc cttttatcaa gaagcgcaaa cacgccaaat tgccgattgg
     6481 ttgatcggca tgaacgcaag ccctttgtat acgttaaatt tacaacagaa gggcgtacaa
     6541 ggtacatttt cactaggacg tgttcaaacg cccaccttat accttatttt tcagcgccag
     6601 gaagccatag agaattttaa aaaagaacct tttttcgagg tggaagctag tataaaagta
     6661 aaccaagggt cgtttaaggg cgttctaagc cccacacagc gttttaaaac ccaagaggag
     6721 cttttagctt ttgtttcttc taaacaagct aaaataggca atcaagaggg gataattgct
     6781 gatgttcaaa ccaaagagaa gaaaacgaat agtccgagtt tgttttcttt aagtagtttg
     6841 caatcaaaag tcaatcagct ttataaagcg acagcgagcc aaactttaaa agctatttct
     6901 tttttaataa cttaaaaata aacttaatgt aacagcaagc acagtcaagg tatacacctt
     6961 tgacaaaaaa tagcacattc tctatcgaaa atttttgctt attttttaaa ttattttggg
     7021 aaattttccc aatccctttt tctaactcaa aaaatataat cactcaaaat ttaaaagggc
     7081 gcacttatac atcattttaa aaaattgatg taacgtgcta agttcaaaac aaagggcgca
     7141 cttatacacg attttcaatc ttgtatattt ctaacgaaaa gcgtgcgcca aaaaaccccc
     7201 ttcgtcaatt ttgacagggg gctttttgat gtaaaaattt ctatcgaaat ttaaaaattc
     7261 gcttcactca tgttataaag acttaaaata aaataactct ttaaaatctt ttgctagttg
     7321 ttcttcaata ttttttattc ggtgcatctt ccaagtaaag tataacacac tagacttatt
     7381 tactacgttt cataagtcat taatgcgtgt gctctgcgag gctagttttt gtgcaagcac
     7441 aaaaaatgga ctgaataaat cagtccataa gttcaaaacc aaattcaaaa tcaaaaccac
     7501 aagcaaccaa aaaatgtggt tgttatacgt tcataaattt tatgatcact tacgtgtata
     7561 aaattaaatt cactttcaaa atctaaaaac taaatccaat catctaccct atgaattata
     7621 tcttgaaatt cattcataaa tagtgaagca tggtaaccat cacatacaga atgatgaagt
     7681 tgcagagcaa ctggtatata aattttatta ttctcactat aaaatttacc tatcgtaata
     7741 ataggcaata aaaagctgct attgttacca atatttaaat taaatgaact aaaatcaatc
     7801 caaggaatca ttgaaatcgg tatggtgttt tcaggtatcg gttttttagg aaacatttct
     7861 tctttatctt tatattcaag caagtcattt ttataattat tataaaaaga aatgaagttt
     7921 ttatcagatt cagtccaaat gttagtaaat ttttcagttt gcttattaaa aactgtatac
     7981 aaaggattta acttatccca ataacctaat ttattctcac tattaattcc tgttctaaac
     8041 actttatttt tatttacaac ttccataatt gcataaatta aagagggata aatttcatat
     8101 cctttctttt ttatcatatc tttaaacaaa gtaatatcaa tttctttagt aatgctataa
     8161 gtagtttgct gattaaaata gtgttcaaaa tattcttttc tatcccaatt ttctaattca
     8221 ataatattaa aagtcatata taacttcctc ctaaatttta aatttttata tttaggagga
     8281 ataatcctct gattttttca tacgttatgt cacctcgtaa atattaatta tactgaatta
     8341 gcaattttta tcaaataaaa cttattttac ttccaaaacc taaattcacg ttgccaaaaa
     8401 tcaatctgct tttgcaattg tttttcgttc gcttttaaag tcgatttcat taattccgtt
     8461 aaatcaattg gagatatttc tctaatcaat tttttaaatt tagtcttagt attcttactt
     8521 agctttcccc acatactttc ttcatgcaac aaagtataaa ccatagcttg ctcattaatt
     8581 ttttctaaag tagcccacgc aggtttcaag atgtgtaaat cattaaaaca atcattccag
     8641 taatcaacca tatctctttt taattcaact tctacacgcc ataaatgttc agacacaact
     8701 tcaacatctg cgttatcttt acgttcttgt tttttattat aaattctaat aaatctatca
     8761 ctatcacgga caccaaaata ttttgtttct ggcttgccat tacgaccata aaaaacagtt
     8821 ttcttaactg ctttatcagt cattgcatag taatcgctca aatcatcttc aaaatcaaaa
     8881 gctaagtcta atcttgtaaa accgtcatct tccatgtagt cgataatatt ttgttttaac
     8941 caaatcattt cttcatgtgt gagtttattg ggattaaatt caacacgcat attacgtcta
     9001 tcccaagtat ctgcttttac tttgtcatat tcgatataaa ctttttcttg aagtgcctta
     9061 gctttaaact ttgtttgaag tatatcccaa agtcgtattt gtggctctac actcataaag
     9121 tcagatagct ttttagcatt agttttgttc aaatttccaa cgattgtcat ggcatcaaaa
     9181 cttaatgcgg gttgagattt tcccaaagtt tgaccactta accggctatt acttaaccgg
     9241 ctattagaga cggccggttt ttttagtgag atttctgcag ctaatttttc atcaattttc
     9301 ttcatttttt atcgctccta aaataatttt tggaacgaaa aaaggacgag tggaatcgca
     9361 aaataaattt cgcctgtatc cattcgtcca ttttgttttg tattcaaaat caaaaattga
     9421 tatactaatc atcgaatgaa taacaagtgt ggtttgttat tccgggcgag aacgttggta
     9481 gcgttgctcg tcttttttta tgtctttttt tcgttaaaac tattttaaaa ctaaatatat
     9541 cttaaagcaa ataaattcaa ggggctaaaa gcgcccctta aaaacccctt gcctctgaaa
     9601 agttttgtgt ttcctttccg tcggtttcaa aagctaattt actcaaaaaa atagatcaag
     9661 ggtaaatgca ctcactgcgt tcgcccttga gctattttat ttcgcaaatt ttaacgcatt
     9721 tgccgacgaa aagataaaac acataaaaat atacgcagat atatttaaaa cgtcttagaa
     9781 cgcaaaattt tacgtttaaa agctatgcaa ggactgtatg aagcaaaatt attgagttat
     9841 ccaagaacag atacaccatt tattacagag aacgaatttg cttatttaaa agcgaatttt
     9901 ggcaaatata gcggtttttt aggacttgat cttgaaatgg ttcaaacaga gcctagaaag
     9961 cgttatgtgg acggtagtaa ggtacaggaa caccacgcca ttatcccaac aaaacaagta
    10021 cctaccgaat ctgcattagc gaaaatggac gatttacaac gaaaaattta tgctttagtc
    10081 gttaaaacga ccgttgccat gtttttacct gattacttgt atgaagaaac caagatacaa
    10141 acgaaagtag ctgatttgct gtttcaatcg atcggaaaga caccaaagca agaagggtgg
    10201 aaaattcttt tcaaacaaca aaccaaagaa gaaaaagagg acgttcaaac gttaccactc
    10261 gttatcattg gcgaacgtgc cgaagttggt gttaagagtg ttgaaaaaga aacgcaaccg
    10321 ccaaaagctt ttacagaggg tacattatta actgctatga aaacggcgaa taaaacggtt
    10381 gatgatgaag aagcaatcaa gattttacaa gaagttgagg ggattggaac agaagcgaca
    10441 agagcaagta ttattgaagc gttaaaacaa aaagaatata tccaagtgat taagaataag
    10501 cttgttgtaa ctgaaaaagg aaaattattg tgccaggcag ttgaaagtca gcacctttta
    10561 acgagtgctg aaatgacggc taaatgggaa acgtatttaa aaaaaatcgg taaaagagaa
    10621 ggcaatcaag agaactttat tacgaatatc aaaaaattca ttgttcattt actggaagct
    10681 gtacctaacg atatagaaaa actaaatttt tctgattacc aggaacagaa agaaaaagaa
    10741 gcagaaaaaa gtattgtagg aaaatgtcct aagtgtggca acaatattgt att
//
LOCUS       DBBGRF010000213         4893 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.105, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000213 DBBGRF010000000
VERSION     DBBGRF010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.105"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..652
                     /locus_tag="ACIZD4_003108"
     CDS             <1..652
                     /locus_tag="ACIZD4_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGC5991925.1"
                     /translation="TVNAAFRKYPSYKESLQDNVTVLKTTSFQPGVYYYSGAWKSNTN
                     SYKDATAWLTGRYATAPNYGSTLNNVIETYNLTQYDTAPTSTSPMYRLYNRHTGEHLY
                     TLNAGEKNYLPTVGWEYEGIAWQAPNSGQPVYRLYNPYSGDHHYTMAQSEINSLTKIG
                     WRYEGLSFYSGGSKPIYRLFNPNEKTGTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            1139..1603
                     /locus_tag="ACIZD4_003109"
     CDS             1139..1603
                     /locus_tag="ACIZD4_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGC5991926.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            1587..2216
                     /locus_tag="ACIZD4_003110"
     CDS             1587..2216
                     /locus_tag="ACIZD4_003110"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGC5991927.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            2570..4048
                     /gene="msr(C)"
                     /locus_tag="ACIZD4_003111"
     CDS             2570..4048
                     /gene="msr(C)"
                     /locus_tag="ACIZD4_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HGC5991928.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            4095..4541
                     /locus_tag="ACIZD4_003112"
     CDS             4095..4541
                     /locus_tag="ACIZD4_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HGC5991929.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(4740..>4893)
                     /locus_tag="ACIZD4_003113"
     CDS             complement(4740..>4893)
                     /locus_tag="ACIZD4_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGC5991930.1"
                     /translation="QKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQQVREQ
                     MQQFFE"
BASE COUNT         1613 a          829 c          994 g         1457 t
ORIGIN      
        1 tacggtgaat gccgctttta gaaaatatcc ttcgtacaaa gaatcattgc aagataacgt
       61 aacggtattg aagacgactt cttttcagcc aggcgtttac tactattccg gtgcatggaa
      121 aagcaatacg aactcttaca aagatgctac ggcttggcta acaggtcgtt atgccactgc
      181 gcctaattat ggttctacat tgaacaatgt aatcgaaacc tataatctga cacagtatga
      241 tacagcacca acttcaactt ctccgatgta tcgtctgtat aaccgtcata caggagaaca
      301 tttatataca ttgaatgccg gagaaaaaaa ttatctgcca actgtaggct gggaatatga
      361 agggattgct tggcaagcac caaacagcgg acaacctgtc taccgtttat acaatcctta
      421 cagtggagac catcattaca caatggcaca atctgagatc aactctttaa caaaaatcgg
      481 ttggcgttat gaaggtctaa gtttttattc tggtggttcc aagccaattt atcgactatt
      541 taatccaaat gaaaaaactg gtacccatca ctataccttg agtgctaagg aaagagattg
      601 gctaacaccg atgggctgga gatatgaagg aataggattt tatggttatt aaaaagaggt
      661 agtgaaaaag ctgccctgca tcaagtagta agaacagcca aacaaaaaca gattttcatg
      721 ttttttgttt ggttgaactt attaccgcag atgcaagttt ttgaacaccg tttactcaaa
      781 aaaggttgtg acaacatctt gtcataactt ttttattact gtttaagcat actgatccaa
      841 tttctaatat tcgacgggat tcttgcaaaa ggcgatttcg gaaatttttg gcggtgtaaa
      901 attatctact gcagaagagc tatcttctat agtttgataa gaatcaataa tcttggtttt
      961 agcgttgtgc tttctttatc attttttccg ttcattctac aaaaaatttc ttttctctat
     1021 acttttctat tgagagcgtt ttttttatta cacagctgat tctttgactt ttttcttttt
     1081 ttattctatt attgacaagt caatcgttga cgagtcaatt attagaaagg aggaaattat
     1141 gtctttagaa gagattagtc accttttata tcaaatcaaa ttagccgatc aaaaaatcgt
     1201 ccagatcttt gaagaaaata tcggtataag tcttactaga tacgagatca tgatgagact
     1261 gaaagaagaa aatccattgc tacaaagcag tttgcaagaa aagttgcaga ttgatcaagg
     1321 agcagttact cgtcatctga aggtattgga agcaaatggc tatgtttcgc gtcagagaaa
     1381 tcctcagaac aaccgggaag tgtatgtagc gctaacagaa aaagcccaga agaaaatcaa
     1441 gcattgtgaa atggaccata aagatacagg ttccgtgcta tccccggctt tcagcgatgt
     1501 agaaatgaaa caatttctaa cacttttaga taaattgaat acccaacttt gcaatataac
     1561 aacagaaacg aaagaggtta ataataatgg aacaaaaaaa tgatttttca acaattatga
     1621 ctggtagaag atccgttcgc gtatatgatg aaacatacaa aatcccacac gaagaaatgc
     1681 tggaaatgat caaagaagcg acgactgcac cttcttctgt caatatgaaa ccatggcgct
     1741 ttgtggtcgc tgaaagcgag gaagcaaaag aaatcttgcg tcctttgatc cgtttcaata
     1801 cgagacaaaa tgatacttct tctgcaatgg tcatgatttt tggcgatatg caatgttacg
     1861 aatatggcga agaaatctac aaccaagctt acgaatcagg gaagatgcca aaagaagtca
     1921 gagatcaaca attagctgcg atcattcctt attacaagag tttttcaaga gaagaaatga
     1981 acgatgtagt caaagtcgat tctagcttag cggctatgca attcatgtta gttgcgcgtg
     2041 atcatggcta tgaaacaaat ccaattggtg gattcgaagc agatcagttg gcagaggcat
     2101 ttggtttgga taaagaccgt tatgttccag ttattatttt atcaatagga aaagcggtag
     2161 aagaaggtta cgagtctgtt cgtttagcac cagaaaagat cactatgttc gaataaaagg
     2221 ttttcagtta ctattcagta gctattgctt tttttgaatc gtgtgtggta acctaataaa
     2281 aaaggaggtc ggaaaaatga ctgcatcgat gaaattacgt ttcgaacttt tgaataacaa
     2341 ctaaataaat tcaaaagaca tgtataaaca acaatttcat ggatggagta tgtccatttt
     2401 ttcgaacgac agtagaatag gtgaaagcta tgacagattt ggtgatttag tcatagttat
     2461 ttcgttcaga gtaggaaaag atgtgatgca gtttttttgc aaacagattt ttctgctctt
     2521 ttttagtatc gataattgtt gttttacatg aaataggagt gtaaaacata tggaaaattt
     2581 agcagtaaat ataacaaatc tacaagtcag ctttggcaac cagctagaac tatctattga
     2641 ttctcttcgt gtctatcagc aagatcgtat agggatcata ggagaaaatg gtgtcggtaa
     2701 atcgactttg ctcaaactaa tagccggtga actttttccc gatcatggga aaatccaaac
     2761 agagatcacc ttcaactacc tgcctcaatt aacctatctc gctgaagcaa aggacctaaa
     2821 tttggaatta gccagtcatt tccagttaag actggaagaa acttcagagc ggaaatggag
     2881 cggaggggaa gaacgaaaga tcgagttgat acgtcttctt tcttcttatg aacaagggat
     2941 gcttctagac gagccaacaa cccatctaga tagaaaaagt attgatcgac tgattgaaga
     3001 gcttcgttat tattatggta cgctggtttt tgttagtcat gatcgctatt ttctagatga
     3061 gctagcatcg aaaatctggg aagtaaaaga cggagaaatc cgagagtttt cggggaatta
     3121 tagtgcctat ctcactcaaa aggaattgga gaaaaagact cagctacgag aagcagagtc
     3181 gatcatgaaa gagaaaaaac gattggaaaa atcgatccaa gaaaagaaaa aacaagcgga
     3241 aaagttggaa aaagtgtcca gtaaaaagaa aaagcaacaa atcagactgg atcggttgtc
     3301 ttcctctaaa caaaaagaca gtgtacaaaa agccatccaa aagaatgcga aaacattaga
     3361 gagaagactc caaaaaatag gagaaacaac caagccgcag cagatgaaac aaatccgttt
     3421 tccagtacca aaatctcttg aactccacag ccgctatccc atcatgggac aaaatgtcca
     3481 attggaaaga agtgggagaa cattactggt aaatggtgat tttcagtttt ctttaggtaa
     3541 aaaaatcgcg attgtcggtg aaaatggttc aggtaagaca accttattag aacatatccg
     3601 caaacaagga gaaggaatcc ttctctctcc gaaagtaagc tttcaagtat atcagcaaaa
     3661 gggttatcaa atgacatctg aagaatccat cattcgtttt gtcatgagac aaacagagtt
     3721 ttcagaatcg cttgtccgta gtttgctgaa tcacttaggg tttgctcagg aaactttgac
     3781 gaaaccgtta tgtacattaa gtgggggaga agcgacccgt ctgacgattg ctttgctttt
     3841 tactaagcca agtaatgtgt tgctgttaga tgaaccgact aattttattg atatggcaac
     3901 gatcgaagct ttagagaagc taatgcaaat atatccggga acgattttgt ttacttctca
     3961 tgattcttac tttgtcgagc gtacggctga tgaagtttat gaaataaaag ggcagaaaat
     4021 aaaaaaagta cttacgagaa atttttaaat gtgctacgat gattttcgtg acaaatttaa
     4081 aggagtggta cagattgcct acaaataaaa aagaaggaat aatttttaca acaatgatgt
     4141 gttttttgat ggtcttgggg atgagcgcgt ataatttatg gctgcatcaa gatcttcatt
     4201 tatcaagttt gttgattggt ctagtgcctg gattcgtggt ggctttcatt ttggatgtct
     4261 tcatcatcgg tgtgctggcg aaaaaaattg cctttaaact accagtaaat ccagaaagca
     4321 aggtccaaat gatcttaact atttcatgct tgatggtttt aggaatggtg acatgtatgt
     4381 ctttattcgg tgtgatcatg gaacaaggaa tacctgatca attattctct gcttatatga
     4441 atgcttggaa aatgaatgtg attgccgctt taccgttgca gttgatcatc gttggcccgc
     4501 tttcaagaag tgtgctaaaa gcaattcaaa gtaatgaatg atggaacact gttatttgaa
     4561 aaaaggcctt ggcatgcttt ttgtcatagt ctcttgaatg cagttctaga aaaatagtga
     4621 tccgaacgat aggttttggc ctgtcgttcg gatcgctttt tcttttccaa ctgtattgct
     4681 cttttattga agataatttg ctcttcaata gatatttcta gaaaggttct gtttatccct
     4741 tactcaaaaa actgctgcat ttgttctctt acttgctgac accattggag ttcctgctga
     4801 caaagcataa ttctgcgctg gatcacaaca taacgtccaa attcttgttt cttgtctagc
     4861 gagaggtcat tcaatttttt ttgatttttt tgc
//
LOCUS       DBBGRF010000214         4801 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.107, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000214 DBBGRF010000000
VERSION     DBBGRF010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.107"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            90..785
                     /gene="vanR-A"
                     /locus_tag="ACIZD4_003114"
     CDS             90..785
                     /gene="vanR-A"
                     /locus_tag="ACIZD4_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HGC5991931.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            763..1917
                     /locus_tag="ACIZD4_003115"
     CDS             763..1917
                     /locus_tag="ACIZD4_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HGC5991932.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2132..3100
                     /locus_tag="ACIZD4_003116"
     CDS             2132..3100
                     /locus_tag="ACIZD4_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HGC5991933.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3093..4124
                     /gene="vanA"
                     /locus_tag="ACIZD4_003117"
     CDS             3093..4124
                     /gene="vanA"
                     /locus_tag="ACIZD4_003117"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HGC5991934.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4130..4738
                     /locus_tag="ACIZD4_003118"
     CDS             4130..4738
                     /locus_tag="ACIZD4_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HGC5991935.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1481 a          921 c         1119 g         1280 t
ORIGIN      
        1 tggcctttta tcttttacac aattatatgg actttatcct ataatctgat aaattattaa
       61 gggcaaactt atgtgaaagg gtgataacta tgagcgataa aatacttatt gtggatgatg
      121 aacatgaaat tgccgatttg gttgaattat acttaaaaaa cgagaattat acggttttca
      181 aatactatac cgccaaagaa gcattggaat gtatagacaa gtctgagatt gaccttgcca
      241 tattggacat catgcttccc ggcacaagcg gccttactat ctgtcaaaaa ataagggaca
      301 agcacaccta tccgattatc atgctgaccg ggaaagatac agaggtagat aaaattacag
      361 ggttaacaat cggcgcggat gattatataa cgaagccctt tcgcccactg gagttaattg
      421 ctcgggtaaa ggcccagttg cgccgataca aaaaattcag tggagtaaag gagcagaacg
      481 aaaatgttat cgtccactcc ggccttgtca ttaatgttaa cacccatgag tgttatctga
      541 acgagaagca gttatccctt actcccaccg agttttcaat actgcgaatc ctctgtgaaa
      601 acaaggggaa tgtggttagc tccgagctgc tatttcatga gatatggggc gacgaatatt
      661 tcagcaagag caacaacacc atcaccgtgc atatccggca tttgcgcgaa aaaatgaacg
      721 acaccattga taatccgaaa tatataaaaa cggtatgggg ggttggttat aaaattgaaa
      781 aataaaaaaa acgactattc caaactagaa cgaaaacttt acatgtatat cgttgcaatt
      841 gttgtggtag caattgtatt cgtgttgtat attcgttcaa tgatccgagg gaaacttggg
      901 gattggatct taagtatttt ggaaaacaaa tatgacttaa atcacctgga cgcgatgaaa
      961 ttatatcaat attccatacg gaacaatata gatatcttta tttatgtggc gattgtcatt
     1021 agtattctta ttctatgtcg cgtcatgctt tcaaaattcg caaaatactt tgacgagata
     1081 aataccggca ttgatgtact tattcagaac gaagataaac aaattgagct ttctgcggaa
     1141 atggatgtta tggaacaaaa gctcaacaca ttaaaacgga ctctggaaaa gcgagagcag
     1201 gatgcaaagc tggccgaaca aagaaaaaat gacgttgtta tgtacttggc gcacgatatt
     1261 aaaacgcccc ttacatccat tatcggttat ttgagcctgc ttgacgaggc tccagacatg
     1321 ccggtagatc aaaaggcaaa gtatgtgcat atcacgttgg acaaagcgta tcgactcgaa
     1381 cagctaatcg acgagttttt tgagattaca cggtataacc tacaaacgat aacgctaaca
     1441 aaaacgcaca tagacctata ctatatgctg gtgcagatga ccgatgaatt ttatcctcag
     1501 ctttccgcac atggaaaaca ggcggttatt cacgcccccg aggatctgac cgtgtccggc
     1561 gaccctgata aactcgcgag agtctttaac aacattttga aaaacgccgc tgcatacagt
     1621 gaggataaca gcatcattga cattaccgcg ggcctctccg gggatgtggt gtcaatcgaa
     1681 ttcaagaaca ctggaagcat cccaaaagat aagctagctg ccatatttga aaagttctat
     1741 aggctggaca atgctcgttc ttccgatacg ggtggcgcgg gacttggatt ggcgattgca
     1801 aaagaaatta ttgttcagca tggagggcag atttacgcgg aaagcaatga taactatacg
     1861 acgtttaggg tagagcttcc agcgatgcca gacttggttg ataaaaggag gtcctaagag
     1921 atgtatataa ttttttagga aaatctcaag gttatcttta ctttttctta ggaaattaac
     1981 aatttaatat taagaaacgg ctcgttctta cacggtagac ttaataccgt aagaacgagc
     2041 cgttttcgtt cttcagagaa agatttgaca agattaccat tggcatcccc gttttatttg
     2101 gtgcctttca cagaaagggt tggtcttaat tatgaataac atcggcatta ctgtttatgg
     2161 atgtgagcag gatgaggcag atgcattcca tgctctttcg cctcgctttg gcgttatggc
     2221 aacgataatt aacgccaacg tgtcggaatc caacgccaaa tccgcgcctt tcaatcaatg
     2281 tatcagtgtg ggacataaat cagagatttc cgcctctatt cttcttgcgc tgaagagagc
     2341 cggtgtgaaa tatatttcta cccgaagcat cggctgcaat catatagata caactgctgc
     2401 taagagaatg ggcatcactg tcgacaatgt ggcgtactcg ccggatagcg ttgccgatta
     2461 tactatgatg ctaattctta tggcagtacg caacgtaaaa tcgattgtgc gctctgtgga
     2521 aaaacatgat ttcaggttgg acagcgaccg tggcaaggta ctcagcgaca tgacagttgg
     2581 tgtggtggga acgggccaga taggcaaagc ggttattgag cggctgcgag gatttggatg
     2641 taaagtgttg gcttatagtc gcagccgaag tatagaggta aactatgtac cgtttgatga
     2701 gttgctgcaa aatagcgata tcgttacgct tcatgtgccg ctcaatacgg atacgcacta
     2761 tattatcagc cacgaacaaa tacagagaat gaagcaagga gcatttctta tcaatactgg
     2821 gcgcggtcca cttgtagata cctatgagtt ggttaaagca ttagaaaacg ggaaactggg
     2881 cggtgccgca ttggatgtat tggaaggaga ggaagagttt ttctactctg attgcaccca
     2941 aaaaccaatt gataatcaat ttttacttaa acttcaaaga atgcctaacg tgataatcac
     3001 accgcatacg gcctattata ccgagcaagc gttgcgtgat accgttgaaa aaaccattaa
     3061 aaactgtttg gattttgaaa ggagacagga gcatgaatag aataaaagtt gcaatactgt
     3121 ttgggggttg ctcagaggag catgacgtat cggtaaaatc tgcaatagag atagccgcta
     3181 acattaataa agaaaaatac gagccgttat acattggaat tacgaaatct ggtgtatgga
     3241 aaatgtgcga aaaaccttgc gcggaatggg aaaacgacaa ttgctattca gctgtactct
     3301 cgccggataa aaaaatgcac ggattacttg ttaaaaagaa ccatgaatat gaaatcaacc
     3361 atgttgatgt agcattttca gctttgcatg gcaagtcagg tgaagatgga tccatacaag
     3421 gtctgtttga attgtccggt atcccttttg taggctgcga tattcaaagc tcagcaattt
     3481 gtatggacaa atcgttgaca tacatcgttg cgaaaaatgc tgggatagct actcccgcct
     3541 tttgggttat taataaagat gataggccgg tggcagctac gtttacctat cctgtttttg
     3601 ttaagccggc gcgttcaggc tcatccttcg gtgtgaaaaa agtcaatagc gcggacgaat
     3661 tggactacgc aattgaatcg gcaagacaat atgacagcaa aatcttaatt gagcaggctg
     3721 tttcgggctg tgaggtcggt tgtgcggtat tgggaaacag tgccgcgtta gttgttggcg
     3781 aggtggacca aatcaggctg cagtacggaa tctttcgtat tcatcaggaa gtcgagccgg
     3841 aaaaaggctc tgaaaacgca gttataaccg ttcccgcaga cctttcagca gaggagcgag
     3901 gacggataca ggaaacggca aaaaaaatat ataaagcgct cggctgtaga ggtctagccc
     3961 gtgtggatat gtttttacaa gataacggcc gcattgtact gaacgaagtc aatactctgc
     4021 ccggtttcac gtcatacagt cgttatcccc gtatgatggc cgctgcaggt attgcacttc
     4081 ccgaactgat tgaccgcttg atcgtattag cgttaaaggg gtgataagca tggaaatagg
     4141 atttactttt ttagatgaaa tagtacacgg tgttcgttgg gacgctaaat atgccacttg
     4201 ggataatttc accggaaaac cggttgacgg ttatgaagta aatcgcattg tagggacata
     4261 cgagttggct gaatcgcttt tgaaggcaaa agaactggct gctacccaag ggtacggatt
     4321 gcttctatgg gacggttacc gtcctaagcg tgctgtaaac tgttttatgc aatgggctgc
     4381 acagccggaa aataacctga caaaggaaag ttattatccc aatattgacc gaactgagat
     4441 gatttcaaaa ggatacgtgg cttcaaaatc aagccatagc cgcggcagtg ccattgatct
     4501 tacgctttat cgattagaca cgggtgagct tgtaccaatg gggagccgat ttgattttat
     4561 ggatgaacgc tctcatcatg cggcaaatgg aatatcatgc aatgaagcgc aaaatcgcag
     4621 acgtttgcgc tccatcatgg aaaacagtgg gtttgaagca tatagcctcg aatggtggca
     4681 ctatgtatta agagacgaac cataccccaa tagctatttt gatttccccg ttaaataaac
     4741 ttttaaccgt tgcacggaca aacggttctg ttgcaaagtt ttaaataaag aataaaatcc
     4801 c
//
LOCUS       DBBGRF010000215         4246 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.116, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000215 DBBGRF010000000
VERSION     DBBGRF010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.116"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(<1..681)
                     /locus_tag="ACIZD4_003119"
     CDS             complement(<1..681)
                     /locus_tag="ACIZD4_003119"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HGC5991936.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFA"
     gene            807..1928
                     /locus_tag="ACIZD4_003120"
     CDS             807..1928
                     /locus_tag="ACIZD4_003120"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGC5991937.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2186..3688
                     /gene="eat(A)"
                     /locus_tag="ACIZD4_003121"
     CDS             2186..3688
                     /gene="eat(A)"
                     /locus_tag="ACIZD4_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HGC5991938.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            3755..>4246
                     /locus_tag="ACIZD4_003122"
     CDS             3755..>4246
                     /locus_tag="ACIZD4_003122"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGC5991939.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTF"
BASE COUNT         1400 a          777 c          915 g         1154 t
ORIGIN      
        1 agcaaattca gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc
       61 agcaatatta caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt
      121 tcgccaaatg gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa
      181 gacttctaca actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat
      241 ttctccatca cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt
      301 gatcccaaat aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa
      361 tccatttagt aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa
      421 catatcatct aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct
      481 ttcgatgatt tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa
      541 gtcagcaatc aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa
      601 gaggacctca tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc
      661 cccagctatt gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta
      721 tatagaaaaa tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt
      781 acttaagaag aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag
      841 gaagtgcttc ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag
      901 gaagaaaaat caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt
      961 acgcgctcag gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa
     1021 aaatcagcta tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac
     1081 aagcattggg gttagatcta cttgataaac caacggatca aactatccga cttgcttcca
     1141 gttatgcctt aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg
     1201 tcactttagg aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg
     1261 cttctttaga agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg
     1321 atcgaagaaa cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc
     1381 catatacagg tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata
     1441 cgacgctagc tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct
     1501 gggaggtgga tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc
     1561 tttttttgtt gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat
     1621 tggaaaaaaa gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc
     1681 aaacgatcca cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac
     1741 caataatcgc tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc
     1801 caattgtctt aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc
     1861 aaacattaga aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc
     1921 cgaagtagtt gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt
     1981 gagggatccg tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct
     2041 tgtggagaca aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg
     2101 ggtctttttg tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg
     2161 gtcttttttt acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg
     2221 ctacgacagc caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg
     2281 gaaactagga cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca
     2341 aaacaaacta ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca
     2401 acagacaaaa gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga
     2461 gatatgggaa atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag
     2521 agaattcagc acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt
     2581 ggatgacact catttcccgt taatcgatga accaacgaat catttggata tctctggtag
     2641 aaaacaagta gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga
     2701 ccggggattt atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga
     2761 actttatcaa gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga
     2821 aatggctcaa aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga
     2881 aaaagccgaa tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat
     2941 cgatactgaa tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat
     3001 gaaacgatcc aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact
     3061 attaaaagat atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa
     3121 gcgactttta agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat
     3181 tcattttaca atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa
     3241 gtcatccatt atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata
     3301 ccagccaaaa catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac
     3361 gttggcggaa tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg
     3421 aaagcttggg atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca
     3481 acggaaaaaa gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga
     3541 tgaaccattg aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa
     3601 cgtgaaacct gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac
     3661 tgagattatt tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt
     3721 taaggggaac tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga
     3781 aacaacttgg aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa
     3841 aggacagatg caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac
     3901 gaaaatcatc cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg
     3961 tctcagcttg ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga
     4021 tggactgcca agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt
     4081 cccaaatggg gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg
     4141 catcgaagac gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat
     4201 caatgcttat tttcatccga tgcctaatga ggggttcttt acattc
//
LOCUS       DBBGRF010000216         3684 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.124, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000216 DBBGRF010000000
VERSION     DBBGRF010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3684
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.124"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..229
                     /locus_tag="ACIZD4_003123"
     CDS             <1..229
                     /locus_tag="ACIZD4_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991940.1"
                     /translation="DFILYLKLCNRTLLVEDASLSGENERINELIEFIRKNKFRTLEY
                     DDKLVRKIIQSVTVYEGHFVIAFKSGIEMEI"
     gene            372..596
                     /locus_tag="ACIZD4_003124"
     CDS             372..596
                     /locus_tag="ACIZD4_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991941.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            611..1480
                     /locus_tag="ACIZD4_003125"
     CDS             611..1480
                     /locus_tag="ACIZD4_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HGC5991942.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1461..2195
                     /locus_tag="ACIZD4_003126"
     CDS             1461..2195
                     /locus_tag="ACIZD4_003126"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGC5991943.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2228..3136
                     /locus_tag="ACIZD4_003127"
     CDS             2228..3136
                     /locus_tag="ACIZD4_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HGC5991944.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3133..3613
                     /locus_tag="ACIZD4_003128"
                     /pseudo
     CDS             3133..3613
                     /locus_tag="ACIZD4_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1279 a          532 c          800 g         1073 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccctt ttagtagaag atgcctccct
       61 cagtggcgag aacgagcgaa tcaatgagct gattgaattt atccgcaaga acaaattccg
      121 caccttagaa tatgatgata agcttgtaag gaagataatc cagagcgtta cagtctatga
      181 aggccacttc gtcatagcct tcaaatctgg catcgaaatg gaaatatgaa aaccagaagt
      241 aaatagccca tgactctaca gtagagttgt gggttttctt ttgcttgctg attataataa
      301 tattttaata actattgtgt ttatcaacca aatggtttat aatattctta gcgtaaactt
      361 ggaggtgctg tatgactacg gcagaaatga ttaaagaact gtgtgagcaa atgaatataa
      421 gtgtttccga acttgctaga cgtattggcc agactccaca gaatttcaat aaaaaattac
      481 aacgagaaac agtaaccttg gatgagttga aggccattgc tgatgtgcta ggtgtcaagt
      541 ttgtgcaggc atttatttta ccagatggag aagaaataaa aatatctaac gaataaagga
      601 ggatgtttat atggtaggta atgttattca aatagtaaca gagaaattat catctttgcc
      661 ttttatagaa ggcatcgtat tagggggctc acgtgcaaga ggcacccata cagaaaattc
      721 tgatatagat atcggaatct attacaattc agactcattt gacctgacag cgattaatca
      781 aattgctaca gaattggatg ataaaaatag aaacaacctt gttgtgcctc ccggagcgtg
      841 gggtgattgg attaatggcg gcggatggtt atttataaat gggtatcatg ttgacttgat
      901 tttacgtgat ataaaacggg tagaacaaat aatcaaagat acggagcaag gaattgttac
      961 tgccaattat cagaccgggc atccccatgg ttatataagt gcaatgtatc gtggagaatt
     1021 agcgattagt aaaatactat atgctaagaa cgaaagctta tgcgaattaa aaaagcaggc
     1081 agaaatttac cctactgctc taaagaaaag cttgatgaac ttttttatat ttgaagctga
     1141 attctcttta atgtttgtaa aagcaaatgc gggggtagag gataaatatt atattgcagg
     1201 ccatgttttt cgtattattt catgcttaaa tcaagtacta tttgcatgta ataatgctta
     1261 ttgcattaac gaaaagaaag ctataaaact gcttgaaact tttgaatata aacctgaaaa
     1321 atatgccgaa agagttaatc atatttttga agtactcggt ctttctcttt ttgaatgcta
     1381 cgatatgacc gagaaacttt ataaagaagt gaatgaaatt gtatcggaga taaataactt
     1441 tttaaacgag gagagttcag atgaaagaaa acaaatatga tgataatata ttttttcaaa
     1501 aatacagtca aatgagtcgc tcgcagaaag gactggctgg tgcgggagaa tgggagactt
     1561 tgaaaaagat gctacctgat tttaagggta agcgtgtgct tgatttagga tgcggctatg
     1621 gatggcactg tatatatgcg atggaaaacg gtgcttcctc tgtagtaggt gttgatattt
     1681 ctcataaaat gctcgaagta gcaaaaggaa aaacccattt tccacagatt gaatatgaat
     1741 gctgtgccat agaagatgtg gatttcccag aggagagctt tgatgtaata ctaagttcgc
     1801 ttgcgtttca ttatgtagca gactatgaga atttaataaa aaagatatat aggatgctga
     1861 aggctggtgg caatttagtt tttacagttg aacatcctgt ttttactgct catggaacac
     1921 aagactggta ttataacgaa aaaggagaaa tactgcattt cccggtggac aattattatt
     1981 atgagggcaa acggacagct atgtttttgg aagaaaaggt tacaaaatat catagaacac
     2041 tgaccacata tctaaataca ctgctttcaa atagttttat aataaatcag attgtggagc
     2101 cacagccgcc agagaacatg atggatattc cggggatggc ggatgaaatg cgacgcccaa
     2161 tgatgctgat tgtatcggca aaaaagaaga tgtaataata tagaaaaaat aaacgaggag
     2221 tatgtaaatg agatcagaaa aagaaatgat ggatttagta ctttctttag cagaacagga
     2281 tgaacgtatt cgaattgtga cccttgaggg gtcacgcgca aatattaata tacctaaaga
     2341 tgaatttcag gattatgata ttacatattt tgtaagtgat atagaaccgt ttatatctaa
     2401 tgatgactgg cttaatcaat ttgggaatat aataatgatg caaaagccgg aggatatgga
     2461 attattccca cctgaagaaa agggattttc ctatcttatg ctatttgatg attacaataa
     2521 aattgatctt accttattgc ccttggaaga gttagataat tacctaaagg gcgataaatt
     2581 aataaaggtt ctaattgata aagattgtag aattaaaagg gacatagttc cgactgatat
     2641 agattatcat gtaagaaagc caagcgcaag ggagtatgat gattgctgca atgaattttg
     2701 gaatgtaaca ccttatgtta ttaaaggatt gtgccgtaag gaaattttat ttgctattga
     2761 tcattttaat cagattgttc gccatgagct gctgagaatg atatcatgga aggtcggcat
     2821 cgaaacaggc tttaaattaa gtgtaggcaa gaactataag tttattgaaa ggtatatatc
     2881 cgaggatttg tgggagaaac ttttgtccac ctaccggatg gattcctatg aaaacatatg
     2941 ggaagcatta tttctatgcc atcaattgtt cagggcggta tccggtgagg tggcggaaag
     3001 gcttcattat gcctatccgg agtatgatag gaatataaca aaatatacca gggacatgta
     3061 taaaaaatac actggtaaaa ccggctgcct ggatagcaca tatgccgctg atatagaaga
     3121 gaggcgggaa cagtgattac agaaatgaaa gcagggcacc tgaaagatat cgataaaccc
     3181 agcgaaccat ttgaggtgat aggtaagatt ataccgaggt atgaaaacga gaattggacc
     3241 tttacagaat tactctatga agcgccatat ttaaaaagct accaagacga agaggatgaa
     3301 gaggatgagg aggcagattg ccttgaatat attgacaata ctgataagat aatatatctt
     3361 ttatatagaa gatatcgccg tatgtaagga tttcaggggg caaggcatag gcagcgcgct
     3421 tatcaatata tctatagaat gggcaaagca taaaaacttg catggactaa tgcttgaaac
     3481 ccaggacaat aaccttatag cttgtaaatt ctatcataat tgtggtttca aaatcggctc
     3541 cgtcgatact atgttatacg ccaactttga aaacaacttt gaaaaagctg ttttctggta
     3601 tttaaggttt tagaatgcaa ggaacagtga attggagttc gtcttgtggt tctgttgcaa
     3661 agttttaaat aaagaataaa atcc
//
LOCUS       DBBGRF010000217         2766 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.133, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000217 DBBGRF010000000
VERSION     DBBGRF010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.133"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            54..1973
                     /gene="tet(M)"
                     /locus_tag="ACIZD4_003129"
     CDS             54..1973
                     /gene="tet(M)"
                     /locus_tag="ACIZD4_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HGC5991945.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2092..2259
                     /locus_tag="ACIZD4_003130"
     CDS             2092..2259
                     /locus_tag="ACIZD4_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HGC5991946.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(2319..2672)
                     /locus_tag="ACIZD4_003131"
     CDS             complement(2319..2672)
                     /locus_tag="ACIZD4_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGC5991947.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
BASE COUNT          937 a          426 c          540 g          863 t
ORIGIN      
        1 tttatcactg ggatttttat gcccttttgg gtttttgaat ggaggaaaat cacatgaaaa
       61 ttattaatat tggagtttta gctcatgttg atgcaggaaa aactacctta acagaaagct
      121 tattatataa cagtggagcg attacagaat taggaagcgt ggacaaaggt acaacgagga
      181 cggataatac gcttttagaa cgtcagagag gaattacaat tcagacagga ataacctctt
      241 ttcagtggga aaatacgaag gtgaacatca tagacacgcc aggacatatg gatttcttag
      301 cagaagtata tcgttcatta tcagttttag atggggcaat tctactgatt tctgcaaaag
      361 atggcgtaca agcacaaact cgtatattat ttcatgcact taggaaaatg gggattccca
      421 caatcttttt tatcaataag attgaccaaa atggaattga tttatcaacg gtttatcagg
      481 atattaaaga gaaactttct gccgaaattg taatcaaaca gaaggtagaa ctgtatccta
      541 atatgtgtgt gacgaacttt accgaatctg aacaatggga tacggtaata gagggaaacg
      601 atgacctttt agagaaatat atgtccggta aatcattaga agcattggaa ctcgaacaag
      661 aggaaagcat aagatttcag aattgttctc tgttccctct ttatcatgga agtgcaaaaa
      721 gtaatatagg gattgataac cttatagaag ttattactaa taaattttat tcatcaacac
      781 atcgaggtcc gtctgaactt tgcggaaatg ttttcaaaat tgaatataca aaaaaaagac
      841 aacgtcttgc atatatacgc ctttatagtg gagtactaca tttacgagat tcggttagag
      901 tatcagaaaa agaaaaaata aaagttacag aaatgtatac ttcaataaat ggtgaattat
      961 gtaagattga tagagcttat tctggagaaa ttgttatttt gcaaaatgag tttttgaagt
     1021 taaatagtgt tcttggagat acaaaactat tgccacagag aaaaaagatt gaaaatccgc
     1081 accctctact acaaacaact gttgaaccga gtaaacctga acagagagaa atgttgcttg
     1141 atgccctttt ggaaatctca gatagtgatc cgcttctacg atattacgtg gattctacga
     1201 cacatgaaat tatactttct ttcttaggga aagtacaaat ggaagtgatt agtgcactgt
     1261 tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc tacagtcatt tatatggaga
     1321 gaccgttaaa aaatgcagaa tataccattc acatcgaagt gccgccaaat cctttctggg
     1381 cttccattgg tttatctgta tcaccgcttc cgttgggaag tggaatgcag tatgagagct
     1441 cggtttctct tggatactta aatcaatcgt ttcaaaatgc agttatggag gggatacgct
     1501 atggctgtga acaaggattg tatggttgga atgtgacgga ctgtaaaatc tgttttaagt
     1561 atggcttata ctatagccct gttagtaccc cagcagattt tcggatgctt gctcctattg
     1621 tattggaaca agtcttaaaa aaagctggaa cagaattgtt agagccatat cttagtttta
     1681 aaatttatgc gccacaggaa tatctttcac gagcatacaa cgatgctcct aaatattgtg
     1741 cgaacatcgt agacactcaa ttgaaaaata atgaggtcat tcttagtgga gaaatccctg
     1801 ctcggtgtat tcaagaatat cgtagtgatt taactttctt tacaaatgga cgtagtgttt
     1861 gtttaacaga gttaaaaggg taccatgtta ctaccggtga acctgtttgc cagccccgtc
     1921 gtccaaatag tcggatagat aaagtacgat atatgttcaa taaaataact tagtgtattt
     1981 tatgttgtta tataaatatg gtttcttgtt aaataagatg aaatattttt taataaagat
     2041 ttgaattaaa gtgtaaagga ggagatagtt attataaact acaagtggat attgtgtcct
     2101 gtatgtggaa ataaaacacg attaaagata agggaagata ctgaattaaa aaaattcccc
     2161 ctctattgtc cgaaatgcag acaagaaaat ttaattgaaa taaagcagtt caaagtaact
     2221 gtgattacag agccagacgc aaagacgcag agccgataaa atgagattaa tacaatctca
     2281 ttttatcggc tctttccgtt atgtatggat tcttttaatt agtcttcgat gtttcttgct
     2341 tcgttgatac cgctggctaa agattccatt aaggatagtt ctttgtctgt aaagctatcc
     2401 atgtatttct ctatctgtaa tcgtcgggtg ctttttacca agttattagc aggtaagaaa
     2461 aattcatcaa cggaaacatg aagtaacgat acaaggtcat aaagaacttg tatgctgggg
     2521 tgttgccctt tattttcaat attagttaag taccgtgggt caatttcaat caatgctccc
     2581 acttgttcac gagttaaacc tcgtttcaat cgagcttctt taatggctaa accaaaggct
     2641 ctaaaatcat atttatcttc ttttttacgc atagtagacc acctctatac attttattgt
     2701 tcctactgaa ttaaaaacag gtatagaaaa acgtgttata tggtttatag gtttatattt
     2761 aataaa
//
LOCUS       DBBGRF010000218         2663 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.135, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000218 DBBGRF010000000
VERSION     DBBGRF010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.135"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            333..828
                     /gene="dfrF"
                     /locus_tag="ACIZD4_003132"
                     /pseudo
     CDS             333..828
                     /gene="dfrF"
                     /locus_tag="ACIZD4_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322211.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
     gene            933..1589
                     /locus_tag="ACIZD4_003133"
     CDS             933..1589
                     /locus_tag="ACIZD4_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HGC5991948.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            1771..2301
                     /locus_tag="ACIZD4_003134"
     CDS             1771..2301
                     /locus_tag="ACIZD4_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HGC5991949.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT          962 a          340 c          556 g          805 t
ORIGIN      
        1 acataagtgt gttggtatct cttttttgtt gccgtgaaac agcagactat ttcatttctg
       61 cttgattacc ttaaaactta ttagtctatg gtttgtcaag ggcttgttgc gtgagaaatg
      121 ctgaatatca ccctttacaa aacataggct gataagtaac ttttcaaaag cagaaaagaa
      181 atggcaatgc ttataacaat atgatataat gcagatgaag acaaaaaagg aatttgtcga
      241 gctggttagt tcgagataat tttgagtttg ttaagatgtg gtgcacttga tggaatcaca
      301 ggtacgacat catattatgg aggatgaaat agatgatagg tttgattgtt gcgaggtcaa
      361 agaataatgt tataggcaag aatggtaata taccatggaa aataaaggga gaacaaaagc
      421 aatttagaga gttaacaacg ggtaatgtgg ttattatggg gcgaaagtct tatgaagaaa
      481 tcggtcatcc gttgcctaat agaatgaata ttgttgtttc caccacaaca gagtatcaag
      541 gagataattt agtttcagtt aaatcattag aagatgcatt attattggct aaaggacgag
      601 atgtatacat atctggtgga tatggactat ttaaggaagc tttgcaaata gtagataaaa
      661 tgtatatcac agaagtagat ttaaatattg aagatggaga tacattcttt ccagaatttg
      721 atatcaatga ttttgaagtt ttgatagggg aaacacttgg tgaggaagtg aaatatacga
      781 gaacatttta tgtaaggaaa aaatgaattg agtaaatttt ggatttaggg tgttttcata
      841 aatatattgc tttttatgca tatataaatt gttgtaagac aaattccagt ttgtatgggg
      901 cgataaaatc agaatttgag agaggattga atatgaataa ggaatggtct gaacttaata
      961 aaacaatgca ggcacaaata aaaaagaaag atacttataa gaggggtatt gatactttac
     1021 ttactttacg aagtcagtta atacaaacct tagtatcttt caaagaagaa ttatgcagag
     1081 aagattttaa ctcaatcccc ttcataaacg ctgatggtta tcatagtaag acgattgctt
     1141 attctatttg gcatattttc cgcattgaag atatagttgt gcatacagtg ataaatgaag
     1201 atgaacaagt attttttgca ggcaattatc aagagcgtat caattcacct atcattacaa
     1261 caggaaatga actcatgaaa cagcagattg cagacttttc aaaacagctt aatctggaag
     1321 aattatattt atatattttc gaagtatggg aaagcactga gaaaatgctt gaacggttat
     1381 cttatgatga attgaaaaga aaaataccga aagaaagaaa aggatactta gaatcgttga
     1441 atgtagtaaa cgacaatgaa aaagcaattt ggctgattga ttattggtgt aataaagata
     1501 tttgtggact aattcaaatg ccgttttcaa gacattggat tatgcacaca gaagcctgtt
     1561 tgcgtataaa gaacaagata cattcatagg caaaaatttc agtttgtaga actaaggaaa
     1621 ttggaattta aggaggaata aagtatggtt agtgatttta taagagcagc atttccatgg
     1681 attttaatgg gtttatttgt agcaatcagt tgttccctta tgagtaaaaa agagaaataa
     1741 attcctgttt gtatttataa aagagaaaaa atgagaaaag tagttttatt tattgccatg
     1801 agccttgacg gatatattgc ggacggtaat ggtggagtag cttggctaaa tggtcatgga
     1861 aatgacaatg aaaacatcga cacttataca gaatttacca aagatataga tactgtctta
     1921 atggggtgga atacttctca tcaggttgtt actgaacttt ctccgcaaga atgggtatat
     1981 aataaattta caacttatgt attaacacat aaagagtgca attcttccca acaaattcat
     2041 tttacaagtg aaaatcctgt tttattattg gaacggctaa aacaagaagc aggaaaggat
     2101 atttggattt gtggcggagc aaatcttgtt cagcagttgg taagcaaaaa tatgattgat
     2161 aaatattaca tttctgttat tcctactctg ttaggaaatg gggttcgtct tttgggcaac
     2221 atagacaggg aaataaagtt aaggctttgt aaaacacaga cttataacgg aataaccgat
     2281 ttgatttata tgcgtagata actagagaga aacagaaaag ctgttaaacc gacggagcga
     2341 tccgaccacg ttggcgggaa aatccttaag atttttccgc catgcttgca agggggcggt
     2401 tcgcttcggc ggttcggcga gcttgcgagc cgttcaaagc ccccgttatc taacaagggg
     2461 ggcacaaaaa acaagaaaca ctatacacta acaagcggaa aacgctgtat ttataaggca
     2521 aaaccccatt tttacagtag tgatataaat tgtacctata tcactatgaa aattgaatag
     2581 taaatatgag aaagacagtt gatttcaaaa aataagaaat tgattgtcgt tttcttttgc
     2641 agaaatttaa gtgcaggcaa tta
//
LOCUS       DBBGRF010000219         2110 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.141, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000219 DBBGRF010000000
VERSION     DBBGRF010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.141"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            complement(39..341)
                     /locus_tag="ACIZD4_003135"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="ACIZD4_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            434..783
                     /locus_tag="ACIZD4_003136"
                     /pseudo
     CDS             434..783
                     /locus_tag="ACIZD4_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1055..1345)
                     /locus_tag="ACIZD4_003137"
     CDS             complement(1055..1345)
                     /locus_tag="ACIZD4_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGC5991950.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1553..2110)
                     /locus_tag="ACIZD4_003138"
                     /pseudo
     CDS             complement(1553..2110)
                     /locus_tag="ACIZD4_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321659.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          597 a          391 c          309 g          813 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagatta ctgttgcttc tttactaatt taggtttact tgttaagaaa gattatttac
     1561 gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt atcttccact tcatcttttg
     1621 ctttttctaa cttttgaata tattgtttca agcttgagtt ttcagcagtt gcttcgtcta
     1681 atttcttttg tgtatctgtt aactgatttc tacatttgtt ttttcttgtg tcagtgttgc
     1741 gatttgttga ttcaaaccat ttacagtatt ttgtaattct gaaagttttg cttgtgcttc
     1801 ttgtagtctt gctgtccaat ctgcattcag atgattgatt tcatcatttt tttggttgat
     1861 ctcatctagt ttgacattga tttcattttg tttgctttgt agttgtgcat ccttgctgac
     1921 taattgactt tctaagtttt gtttttctgc tgccgattga tttttttggt tttctaattc
     1981 atttactttt gtttggtatt cttggacatc tgcctttgaa tcttgcaatg tctgttcttt
     2041 ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct ttatctgtca atgtatgatc
     2101 aagctgtgtc
//
LOCUS       DBBGRF010000220         1781 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.147, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000220 DBBGRF010000000
VERSION     DBBGRF010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.147"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            24..416
                     /locus_tag="ACIZD4_003139"
     CDS             24..416
                     /locus_tag="ACIZD4_003139"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGC5991951.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            417..>1781
                     /gene="aph(2'')-I"
                     /locus_tag="ACIZD4_003140"
     CDS             417..>1781
                     /gene="aph(2'')-I"
                     /locus_tag="ACIZD4_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HGC5991952.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVY"
BASE COUNT          731 a          136 c          303 g          611 t
ORIGIN      
        1 tatagttgaa gaatattatc ctattgaaac tattgtttat tgatgataat atggtttttg
       61 atattgataa tttaaaagga tttcttaatg ataccagttc atttgggttt atagctaaag
      121 aaaataataa aattatagga tttgcatatt gctatacact tttaagacct gatggaaaaa
      181 caatgtttta tttacactca ataggaatgt tacctaacta tcaagacaaa ggttatggtt
      241 caaaattatt atcttttatt aaggaatatt ctaaagagat tggttgttct gaaatgtttt
      301 taataactga taaaggtaat cctagagctt gccatgtata tgaaaaatta ggtggtaaaa
      361 atgattataa agatgaaata gtatatgtat atgattatga aaaaggtgat aaataaatga
      421 atatagttga aaatgaaata tgtataagaa ctttaataga tgatgatttt cctttgatgt
      481 taaaatggtt aactgatgaa agagtattag aattttatga tggtagagat aaaaaatata
      541 cattagaatc attaaaaaaa cattatacag agccttggga agatgaagtt tttagagtaa
      601 ttattgaata taacaatgtt cctattggat atggacaaat atataaaatg tatgatgagt
      661 tatatactga ttatcattat ccaaaaactg atgagatagt ctatggtatg gatcaattta
      721 taggagagcc aaattattgg agtaaaggaa ttggtacaag atatattaaa ttgatttttg
      781 aatttttgaa aaaagaaaga aatgctaatg cagttatttt agaccctcat aaaaataatc
      841 caagagcaat aagggcatac caaaaatctg gttttagaat tattgaagat ttgccagaac
      901 atgaattaca cgagggcaaa aaagaagatt gttatttaat ggaatataga tatgatgata
      961 atgccacaaa tgttaaggca atgaaatatt taattgagca ttactttgat aatttcaaag
     1021 tagatagtat tgaaataatc ggtagtggtt atgatagtgt ggcatattta gttaataatg
     1081 aatacatttt taaaacaaaa tttagtacta ataagaaaaa aggttatgca aaagaaaaag
     1141 caatatataa ttttttaaat acaaatttag aaactaatgt aaaaattcct aatattgaat
     1201 attcgtatat tagtgatgaa ttatctatac taggttataa agaaattaaa ggaacttttt
     1261 taacaccaga aatttattct actatgtcag aagaagaaca aaatttgtta aaacgagata
     1321 ttgccagttt tttaagacaa atgcacggtt tagattatac agatattagt gaatgtacta
     1381 ttgataataa acaaaatgta ttagaagagt atatattgtt gcgtgaaact atttataatg
     1441 atttaactga tatagaaaaa gattatatag aaagttttat ggaaagacta aatgcaacaa
     1501 cagtttttga gggtaaaaag tgtttatgcc ataatgattt tagttgtaat catctattgt
     1561 tagatggcaa taatagatta actggaataa ttgattttgg agattctgga attatagatg
     1621 aatattgtga ttttatatac ttacttgaag atagtgaaga agaaatagga acaaattttg
     1681 gagaagatat attaagaatg tatggaaata tagatattga gaaagcaaaa gaatatcaag
     1741 atatagttga agaatattat cctattgaaa ctattgttta t
//
LOCUS       DBBGRF010000221         1517 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.153, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000221 DBBGRF010000000
VERSION     DBBGRF010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.153"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            <1..1103
                     /locus_tag="ACIZD4_003141"
                     /note="aph(2'')-Ia"
     CDS             <1..1103
                     /locus_tag="ACIZD4_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HGC5991953.1"
                     /translation="TRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIE
                     DLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSV
                     AYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILG
                     YKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEE
                     YILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLT
                     GIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEY
                     YPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1233..>1517)
                     /locus_tag="ACIZD4_003142"
     CDS             complement(1233..>1517)
                     /locus_tag="ACIZD4_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGC5991954.1"
                     /translation="PYLIVDLKLCNRTACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          607 a          144 c          258 g          508 t
ORIGIN      
        1 gtacaagata tattaaattg atttttgaat ttttgaaaaa agaaagaaat gctaatgcag
       61 ttattttaga ccctcataaa aataatccaa gagcaataag ggcataccaa aaatctggtt
      121 ttagaattat tgaagatttg ccagaacatg aattacacga gggcaaaaaa gaagattgtt
      181 atttaatgga atatagatat gatgataatg ccacaaatgt taaggcaatg aaatatttaa
      241 ttgagcatta ctttgataat ttcaaagtag atagtattga aataatcggt agtggttatg
      301 atagtgtggc atatttagtt aataatgaat acatttttaa aacaaaattt agtactaata
      361 agaaaaaagg ttatgcaaaa gaaaaagcaa tatataattt tttaaataca aatttagaaa
      421 ctaatgtaaa aattcctaat attgaatatt cgtatattag tgatgaatta tctatactag
      481 gttataaaga aattaaagga acttttttaa caccagaaat ttattctact atgtcagaag
      541 aagaacaaaa tttgttaaaa cgagatattg ccagtttttt aagacaaatg cacggtttag
      601 attatacaga tattagtgaa tgtactattg ataataaaca aaatgtatta gaagagtata
      661 tattgttgcg tgaaactatt tataatgatt taactgatat agaaaaagat tatatagaaa
      721 gttttatgga aagactaaat gcaacaacag tttttgaggg taaaaagtgt ttatgccata
      781 atgattttag ttgtaatcat ctattgttag atggcaataa tagattaact ggaataattg
      841 attttggaga ttctggaatt atagatgaat attgtgattt tatatactta cttgaagata
      901 gtgaagaaga aataggaaca aattttggag aagatatatt aagaatgtat ggaaatatag
      961 atattgagaa agcaaaagaa tatcaagata tagttgaaga atattatcct attgaaacta
     1021 ttgtttatgg aattaaaaat attaaacagg aatttatcga aaatggtaga aaagaaattt
     1081 ataaaaggac ttataaagat tgattatata atatatgaaa agctattata aaagacatta
     1141 gtattaaata gtttaaaaaa atgaaaaata ataaaggaag tgagtcaatt ccagactcct
     1201 gtgtaaaatg ctatacaatg tttttaccat ttctacttat caaaattgat gtattttctt
     1261 gaagaataaa tccattcatc atgtaggtcc ataagaacgg ctccaattaa gcgattggct
     1321 gatgtttgat tggggaagat gcgaataatc ttttctcttc tgcgtacttc ttgattcagt
     1381 cgttcaatta gattggtact ctttagtcga ttgtgggaat ttccttgtac ggtatattga
     1441 aaggcgtctt cgaatccatc atccaatgat gcgcaagcgg ttctgttgca aagttttaaa
     1501 tctactatca aataagg
//
LOCUS       DBBGRF010000222         1149 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.168, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000222 DBBGRF010000000
VERSION     DBBGRF010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.168"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            27..77
                     /locus_tag="ACIZD4_003143"
     CDS             27..77
                     /locus_tag="ACIZD4_003143"
                     /inference="COORDINATES: protein motif:HMM:NF018061.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HGC5991955.1"
                     /translation="MWTLSKQTKNSDYADK"
     gene            202..939
                     /gene="erm(B)"
                     /locus_tag="ACIZD4_003144"
     CDS             202..939
                     /gene="erm(B)"
                     /locus_tag="ACIZD4_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HGC5991956.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
BASE COUNT          421 a          200 c          185 g          343 t
ORIGIN      
        1 catggccttt tatcttttac acaattatat ggactttatc gaaacagact aaaaacagtg
       61 attacgcaga taaataaata cgttagatta attcctacca gtgactaatc ttatgacttt
      121 ttaaacagat aactaaaatt acaaacaaat cgtttaactt ctgtatttgt ttatagatgt
      181 aatcacttca ggagagatta catgaacaaa aatataaaat attctcaaaa ctttttaacg
      241 agtgaaaaag tactcaacca aataataaaa caattgaatt taaaagaaac cgataccgtt
      301 tacgaaattg gaacaggtaa agggcattta acgacgaaac tggctaaaat aagtaaacag
      361 gtaacgtcta ttgaattaga cagtcatcta ttcaacttat cgtcagaaaa attaaaactg
      421 aatactcgtg tcactttaat tcaccaagat attctacagt ttcaattccc taacaaacag
      481 aggtataaaa ttgttgggaa tattccttac catttaagca cacaaattat taaaaaagtg
      541 gtttttgaaa gccgtgcgtc tgacatctat ctgattgttg aagaaggatt ctacaagcgt
      601 accttggata ttcaccgaac actagggttg ctcttgcaca ctcaagtctc gattcagcaa
      661 ttgcttaagc tgccagcgga atgctttcat cctaaaccaa aagtaaacag tgtcttaata
      721 aaacttaccc gccataccac agatgttcca gataaatatt ggaagctata tacgtacttt
      781 gtttcaaaat gggtcaatcg agaatatcgt caactgttta ctaaaaatca gtttcatcaa
      841 gcaatgaaac acgccaaagt aaacaattta agtaccatta cttatgagca agtattgtct
      901 atttttaata gttatctatt atttaacggg aggaaataat tctatgagtc gcttttttaa
      961 atttggaaag ttacacgtta ctaaagggaa tggagataaa ttattagata tactactgac
     1021 agcttccaag aagctaaaga ggtccctagc gcctacgggg aatttgtatc gataaggggt
     1081 acaaattccc actaagcgct cgggacccct tgtaggaaaa tgtcctaagt gtggcaacaa
     1141 tattgtatt
//
LOCUS       DBBGRF010000223          828 bp    DNA     linear   BCT 08-NOV-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate clinical isolate
            SAMEA115345671-rid23690733.guided.181, whole genome shotgun
            sequence.
ACCESSION   DBBGRF010000223 DBBGRF010000000
VERSION     DBBGRF010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115345671
            Sequence Read Archive: ERR12711010
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-OCT-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002429634.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002429634.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/06/2024 15:17:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,145
            CDSs (total)                      :: 3,080
            Genes (coding)                    :: 2,985
            CDSs (with protein)               :: 2,985
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 95
            CDSs (without protein)            :: 95
            Pseudo Genes (ambiguous residues) :: 0 of 95
            Pseudo Genes (frameshifted)       :: 43 of 95
            Pseudo Genes (incomplete)         :: 46 of 95
            Pseudo Genes (internal stop)      :: 21 of 95
            Pseudo Genes (multiple problems)  :: 12 of 95
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115345671-rid23690733.guided.181"
                     /isolate="clinical isolate"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /lat_lon="47.4 N 8.5 E"
                     /collection_date="1905-07-13"
     gene            215..763
                     /gene="aac(6')"
                     /locus_tag="ACIZD4_003145"
     CDS             215..763
                     /gene="aac(6')"
                     /locus_tag="ACIZD4_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HGC5991957.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          294 a          124 c          178 g          232 t
ORIGIN      
        1 tcatgatgaa caaacagagt tttttcctcc aattgatggc tttcctgatc tttcctattt
       61 tgaataaagt gtttctgtat aattttttta ttttataagt aagataaata atgaaagaat
      121 agagatactg attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga
      181 ctgttagaat aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa
      241 taatccagta ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata
      301 tggagacagc tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc
      361 agcggtagac caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac
      421 aggttgggaa ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac
      481 tcgattagtc aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt
      541 aggtacggat gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac
      601 atttgataaa gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa
      661 attaggttat aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat
      721 ttggatggca aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac
      781 agaagtaatc agcttcaaga aataagaagg aatttacgaa aattactt
//
